Guide to the Human Genome
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Search of human proteins with 30181246

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30181246 doublecortin isoform a [Homo sapiens]
         (441 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30181246 doublecortin isoform a [Homo sapiens]                     890   0.0  
gi|30181244 doublecortin isoform c [Homo sapiens]                     721   0.0  
gi|30181240 doublecortin isoform c [Homo sapiens]                     721   0.0  
gi|30181242 doublecortin isoform b [Homo sapiens]                     715   0.0  
gi|4758128 doublecortin-like kinase 1 [Homo sapiens]                  508   e-144
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]      473   e-133
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]      473   e-133
gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]             96   6e-20
gi|117938307 doublecortin domain containing 2 [Homo sapiens]           96   8e-20
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              82   1e-15
gi|239753110 PREDICTED: doublecortin domain-containing protein E...    71   2e-12
gi|239747673 PREDICTED: doublecortin domain-containing protein E...    71   2e-12
gi|239741542 PREDICTED: doublecortin domain-containing protein E...    71   2e-12
gi|150456471 doublecortin domain containing 2B [Homo sapiens]          70   5e-12
gi|38569480 megakaryoblastic leukemia 2 protein [Homo sapiens]         40   0.006
gi|153070260 myristoylated alanine-rich protein kinase C substra...    37   0.027
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    37   0.047
gi|239754761 PREDICTED: hypothetical protein [Homo sapiens]            37   0.047
gi|239749289 PREDICTED: hypothetical protein XP_002346983 [Homo ...    37   0.047
gi|239743379 PREDICTED: hypothetical protein XP_002342845 [Homo ...    37   0.047
gi|239509073 PREDICTED: hypothetical protein [Homo sapiens]            37   0.047
gi|163965366 nascent polypeptide-associated complex alpha subuni...    36   0.061
gi|118572603 ubinuclein 1 [Homo sapiens]                               36   0.080
gi|118572601 ubinuclein 1 [Homo sapiens]                               36   0.080
gi|41281612 zinc finger protein 828 [Homo sapiens]                     35   0.10 
gi|42716277 transmembrane protein 24 [Homo sapiens]                    35   0.10 
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s...    35   0.14 
gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo s...    35   0.14 
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          35   0.18 
gi|149408146 TOX high mobility group box family member 2 isoform...    35   0.18 

>gi|30181246 doublecortin isoform a [Homo sapiens]
          Length = 441

 Score =  890 bits (2300), Expect = 0.0
 Identities = 441/441 (100%), Positives = 441/441 (100%)

Query: 1   MKTLPLHSHCTEMQRLLPKLEMLTLGSSFCSLQGEFCQAMDSFTTVSHVGMCEETDASFN 60
           MKTLPLHSHCTEMQRLLPKLEMLTLGSSFCSLQGEFCQAMDSFTTVSHVGMCEETDASFN
Sbjct: 1   MKTLPLHSHCTEMQRLLPKLEMLTLGSSFCSLQGEFCQAMDSFTTVSHVGMCEETDASFN 60

Query: 61  VFSPKFQFDRSHCQSLRFHQNMELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYR 120
           VFSPKFQFDRSHCQSLRFHQNMELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYR
Sbjct: 61  VFSPKFQFDRSHCQSLRFHQNMELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYR 120

Query: 121 TRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQ 180
           TRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQ
Sbjct: 121 TRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQ 180

Query: 181 GVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAP 240
           GVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAP
Sbjct: 181 GVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAP 240

Query: 241 QSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIK 300
           QSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIK
Sbjct: 241 QSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIK 300

Query: 301 LETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPS 360
           LETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPS
Sbjct: 301 LETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPS 360

Query: 361 ATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLR 420
           ATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLR
Sbjct: 361 ATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLR 420

Query: 421 KHKDLYLPLSLDDSDSLGDSM 441
           KHKDLYLPLSLDDSDSLGDSM
Sbjct: 421 KHKDLYLPLSLDDSDSLGDSM 441


>gi|30181244 doublecortin isoform c [Homo sapiens]
          Length = 360

 Score =  721 bits (1862), Expect = 0.0
 Identities = 360/360 (100%), Positives = 360/360 (100%)

Query: 82  MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRN 141
           MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRN
Sbjct: 1   MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRN 60

Query: 142 GDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELE 201
           GDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELE
Sbjct: 61  GDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELE 120

Query: 202 EGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPK 261
           EGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPK
Sbjct: 121 EGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPK 180

Query: 262 LVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLH 321
           LVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLH
Sbjct: 181 LVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLH 240

Query: 322 DFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGP 381
           DFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGP
Sbjct: 241 DFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGP 300

Query: 382 MRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM 441
           MRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM
Sbjct: 301 MRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM 360


>gi|30181240 doublecortin isoform c [Homo sapiens]
          Length = 360

 Score =  721 bits (1862), Expect = 0.0
 Identities = 360/360 (100%), Positives = 360/360 (100%)

Query: 82  MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRN 141
           MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRN
Sbjct: 1   MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRN 60

Query: 142 GDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELE 201
           GDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELE
Sbjct: 61  GDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELE 120

Query: 202 EGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPK 261
           EGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPK
Sbjct: 121 EGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPK 180

Query: 262 LVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLH 321
           LVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLH
Sbjct: 181 LVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLH 240

Query: 322 DFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGP 381
           DFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGP
Sbjct: 241 DFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGP 300

Query: 382 MRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM 441
           MRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM
Sbjct: 301 MRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM 360


>gi|30181242 doublecortin isoform b [Homo sapiens]
          Length = 365

 Score =  715 bits (1846), Expect = 0.0
 Identities = 360/365 (98%), Positives = 360/365 (98%), Gaps = 5/365 (1%)

Query: 82  MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRN 141
           MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRN
Sbjct: 1   MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRN 60

Query: 142 GDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELE 201
           GDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELE
Sbjct: 61  GDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELE 120

Query: 202 EGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPK 261
           EGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPK
Sbjct: 121 EGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPK 180

Query: 262 LVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLH 321
           LVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLH
Sbjct: 181 LVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLH 240

Query: 322 DFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGP 381
           DFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGP
Sbjct: 241 DFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGP 300

Query: 382 MRRSKSPADS-----ANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDS 436
           MRRSKSPADS     ANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDS
Sbjct: 301 MRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDS 360

Query: 437 LGDSM 441
           LGDSM
Sbjct: 361 LGDSM 365


>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
          Length = 729

 Score =  508 bits (1308), Expect = e-144
 Identities = 258/352 (73%), Positives = 301/352 (85%), Gaps = 11/352 (3%)

Query: 76  LRFHQNMELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKK 135
           + F ++MEL+  HFDERDK  R  RGSR+NGLPSPTHSAHCSFYRTRTLQ LS+EKKAKK
Sbjct: 1   MSFGRDMELE--HFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKK 58

Query: 136 VRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIG 195
           VRFYRNGDRYFKGIVYA+S DRFRSF+ALLADLTR+LSDN+NLPQGVR IYTIDG +KI 
Sbjct: 59  VRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKIS 118

Query: 196 SMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASS--NSAQARE 253
           S+D+L EGESYVC S   FKK+EYTKNVNPNWSVNVKT++  +A  SLA++  + ++ RE
Sbjct: 119 SLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRE 178

Query: 254 NKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLD 313
           NKDF+RPKLVTIIRSGVKPRKAVR+LLNKKTAHSFEQVLTDIT+AIKL++GVVK+LYTLD
Sbjct: 179 NKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLD 238

Query: 314 GKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQK 373
           GKQV CL DFFGDDD+FIACGPEKFRY QDDF LDE+ECRV+K    +T+  K + + ++
Sbjct: 239 GKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVK----STSYTKIASSSRR 293

Query: 374 TSAKSPGPMRRSKSPA--DSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHK 423
           ++ KSPGP RRSKSPA   S NGT  SQLSTP+S +SP  +PTSPGSLRK +
Sbjct: 294 STTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQR 345


>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
          Length = 766

 Score =  473 bits (1218), Expect = e-133
 Identities = 245/357 (68%), Positives = 286/357 (80%), Gaps = 24/357 (6%)

Query: 84  LDFGHFDERDKTSR--------------NMRGSRMNGL-PSPTHSAHCSFYRTRTLQALS 128
           ++  HF+ERDK  R              +  G + NGL PSP HSAHCSFYRTRTLQALS
Sbjct: 7   IELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTRTLQALS 66

Query: 129 NEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTI 188
           +EKKAKK RFYRNGDRYFKG+V+A+SSDRFRSFDALL +LTRSLSDN+NLPQGVR IYTI
Sbjct: 67  SEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTI 126

Query: 189 DGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNS 248
           DGSRK+ S+DEL EGESYVC+S+  F+KV+YTKN+NPNWSVN+K   +     + ASS  
Sbjct: 127 DGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRAL--AAASSVK 184

Query: 249 AQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKK 308
           ++ +E+KDF++PKLVT+IRSGVKPRKAVR+LLNKKTAHSFEQVLTDITEAIKL++GVVK+
Sbjct: 185 SEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKR 244

Query: 309 LYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKAS 368
           L TLDGKQVTCL DFFGDDDVFIACGPEKFRYAQDDF LD +ECRV+K + S ++  K S
Sbjct: 245 LCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYS 304

Query: 369 PTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDL 425
                  +KSPGP RRSKSPA S NGT SSQLSTPKS +S  S+PTSPGS R  K +
Sbjct: 305 ------GSKSPGPSRRSKSPA-SVNGTPSSQLSTPKSTKSSSSSPTSPGSFRGLKQI 354


>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
          Length = 765

 Score =  473 bits (1216), Expect = e-133
 Identities = 244/352 (69%), Positives = 284/352 (80%), Gaps = 24/352 (6%)

Query: 84  LDFGHFDERDKTSR--------------NMRGSRMNGL-PSPTHSAHCSFYRTRTLQALS 128
           ++  HF+ERDK  R              +  G + NGL PSP HSAHCSFYRTRTLQALS
Sbjct: 7   IELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTRTLQALS 66

Query: 129 NEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTI 188
           +EKKAKK RFYRNGDRYFKG+V+A+SSDRFRSFDALL +LTRSLSDN+NLPQGVR IYTI
Sbjct: 67  SEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTI 126

Query: 189 DGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNS 248
           DGSRK+ S+DEL EGESYVC+S+  F+KV+YTKN+NPNWSVN+K   +     + ASS  
Sbjct: 127 DGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRAL--AAASSVK 184

Query: 249 AQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKK 308
           ++ +E+KDF++PKLVT+IRSGVKPRKAVR+LLNKKTAHSFEQVLTDITEAIKL++GVVK+
Sbjct: 185 SEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKR 244

Query: 309 LYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKAS 368
           L TLDGKQVTCL DFFGDDDVFIACGPEKFRYAQDDF LD +ECRV+K + S ++  K S
Sbjct: 245 LCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYS 304

Query: 369 PTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLR 420
                  +KSPGP RRSKSPA S NGT SSQLSTPKS +S  S+PTSPGS R
Sbjct: 305 ------GSKSPGPSRRSKSPA-SVNGTPSSQLSTPKSTKSSSSSPTSPGSFR 349


>gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
          Length = 2156

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 68/215 (31%), Positives = 108/215 (50%), Gaps = 15/215 (6%)

Query: 126 ALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYI 185
           +L++   AK++ FY++GD  F G+   V+   F+SFDALL +L+R     + LP GVR I
Sbjct: 28  SLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRK----VPLPFGVRNI 83

Query: 186 YTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTK-NVNPNWSVNVKTSANMKAPQSLA 244
            T  G   I  ++ELE+GESY+CS     + V+  K    P   ++ +  +    P  +A
Sbjct: 84  STPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVA 143

Query: 245 SSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETG 304
            +     R       P+ + + R+G  P+    VLL+++   SFE  L  +TE ++    
Sbjct: 144 VAAPGMPRP------PRSLVVFRNG-DPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRP-- 194

Query: 305 VVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 339
            V KLY  DG++V  L          +A G E F+
Sbjct: 195 -VVKLYATDGRRVPSLQAVILSSGAVVAAGREPFK 228


>gi|117938307 doublecortin domain containing 2 [Homo sapiens]
          Length = 476

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 80/282 (28%), Positives = 123/282 (43%), Gaps = 25/282 (8%)

Query: 134 KKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQG-VRYIYTIDGSR 192
           K V  YRNGD ++ G    +   +  SF+  L ++T      +  P G VR IYT     
Sbjct: 17  KSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVT----GGVQAPFGAVRNIYTPRTGH 72

Query: 193 KIGSMDELEEGESYVCSSDNFFKKVEYTK----NVNPNWSVNVKTSANMKAPQSLASSNS 248
           +I  +D+++ G +YV      FKK+ Y         P   VN +          + S  +
Sbjct: 73  RIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKP------VIHSRIN 126

Query: 249 AQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKK 308
             AR  K    P  + +I +G     A R+L+ +KT + ++ VL  +TE I L +G V +
Sbjct: 127 VSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHR 186

Query: 309 LYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKAS 368
           LYTL+GK V    +   +   ++A G +KF+       L  +E    K       G KAS
Sbjct: 187 LYTLEGKLVESGAE-LENGQFYVAVGRDKFK------KLPYSELLFDKSTMRRPFGQKAS 239

Query: 369 PTPQ---KTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQ 407
             P       +K  G  R SKS   S++ +S   L     K+
Sbjct: 240 SLPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKE 281


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 85/353 (24%), Positives = 145/353 (41%), Gaps = 43/353 (12%)

Query: 104 MNGLP----SPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFR 159
           MN  P    +P+H   C         +++    AKK+ F + GD  F G+  AV    F+
Sbjct: 1   MNSTPRNAQAPSHR-ECFLPSVARTPSVTKVTPAKKITFLKRGDPRFAGVRLAVHQRAFK 59

Query: 160 SFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEY 219
           +F AL+ +    LS  + L  GVR + T  G   + ++++LE+G  Y+CS     KK   
Sbjct: 60  TFSALMDE----LSQRVPLSFGVRSVTTPRGLHSLSALEQLEDGGCYLCSD----KKPPK 111

Query: 220 T-------KNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKP 272
           T       +  NP            +AP + +S  S +         P+ + +I++ + P
Sbjct: 112 TPSGPGRPQERNPTAQQLRDVEGQREAPGTSSSRKSLKT--------PRRILLIKN-MDP 162

Query: 273 RKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIA 332
           R    V+L+ +   +    L   ++ ++     VK+LYT  GK+V  L        V + 
Sbjct: 163 RLQQTVVLSHRNTRNLAAFLGKASDLLRFP---VKQLYTTSGKKVDSLQALLHSPSVLVC 219

Query: 333 CGPEKFRYAQDDFSLDENECRVMKG----NPSATAGPKASPTPQKTSAKSPGPMRRSKSP 388
            G E FR      +   +E   + G    N + + GPK  P+   + +      R  + P
Sbjct: 220 AGHEAFRTPAMK-NARRSEAETLSGLTSRNKNGSWGPKTKPSVIHSRSPPGSTPRLPERP 278

Query: 389 ADSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM 441
                G S+  +  P   + P  TP   G L    D+   + +++  SL   M
Sbjct: 279 -----GPSNPPVG-PAPGRHPQDTPAQSGPLVAGDDMKKKVRMNEDGSLSVEM 325


>gi|239753110 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 530

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 59/241 (24%), Positives = 111/241 (46%), Gaps = 9/241 (3%)

Query: 100 RGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFR 159
           R  R   L +P      +   TR   A  +   AK +  YRNGD ++ G  + +S  R  
Sbjct: 52  RCPRCRSLSAPASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAA 111

Query: 160 SFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEY 219
           +F+ALL  LT    + +++P GVR ++T     ++  +D L+ G  YV +    FK+++Y
Sbjct: 112 TFEALLEQLT----EQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDY 167

Query: 220 TKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVL 279
             ++ P     ++    +K P      N     +    +  + + +  +G       +++
Sbjct: 168 I-HIVPRKPAKIRKLKEIK-PVVHCDINVPSKWQTYHRI-SRHINVFTNGRLFIPPAKII 224

Query: 280 LNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 339
           + K +   ++ VL  I E +    G V+KL+T++G  +    D   D+  ++A G E F+
Sbjct: 225 IPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLLGDSKD-LQDNHFYVAVGLETFK 282

Query: 340 Y 340
           Y
Sbjct: 283 Y 283


>gi|239747673 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 714

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 59/241 (24%), Positives = 111/241 (46%), Gaps = 9/241 (3%)

Query: 100 RGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFR 159
           R  R   L +P      +   TR   A  +   AK +  YRNGD ++ G  + +S  R  
Sbjct: 158 RCPRCRSLSAPASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAA 217

Query: 160 SFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEY 219
           +F+ALL  LT    + +++P GVR ++T     ++  +D L+ G  YV +    FK+++Y
Sbjct: 218 TFEALLEQLT----EQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDY 273

Query: 220 TKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVL 279
             ++ P     ++    +K P      N     +    +  + + +  +G       +++
Sbjct: 274 I-HIVPRKPAKIRKLKEIK-PVVHCDINVPSKWQTYHRI-SRHINVFTNGRLFIPPAKII 330

Query: 280 LNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 339
           + K +   ++ VL  I E +    G V+KL+T++G  +    D   D+  ++A G E F+
Sbjct: 331 IPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLLGDSKD-LQDNHFYVAVGLETFK 388

Query: 340 Y 340
           Y
Sbjct: 389 Y 389


>gi|239741542 PREDICTED: doublecortin domain-containing protein
           ENSP00000382097-like [Homo sapiens]
          Length = 510

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 59/241 (24%), Positives = 111/241 (46%), Gaps = 9/241 (3%)

Query: 100 RGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFR 159
           R  R   L +P      +   TR   A  +   AK +  YRNGD ++ G  + +S  R  
Sbjct: 158 RCPRCRSLSAPASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAA 217

Query: 160 SFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEY 219
           +F+ALL  LT    + +++P GVR ++T     ++  +D L+ G  YV +    FK+++Y
Sbjct: 218 TFEALLEQLT----EQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDY 273

Query: 220 TKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVL 279
             ++ P     ++    +K P      N     +    +  + + +  +G       +++
Sbjct: 274 I-HIVPRKPAKIRKLKEIK-PVVHCDINVPSKWQTYHRI-SRHINVFTNGRLFIPPAKII 330

Query: 280 LNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 339
           + K +   ++ VL  I E +    G V+KL+T++G  +    D   D+  ++A G E F+
Sbjct: 331 IPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLLGDSKD-LQDNHFYVAVGLETFK 388

Query: 340 Y 340
           Y
Sbjct: 389 Y 389


>gi|150456471 doublecortin domain containing 2B [Homo sapiens]
          Length = 349

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 68/294 (23%), Positives = 120/294 (40%), Gaps = 30/294 (10%)

Query: 133 AKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSR 192
           AK+V  YRNGD +F G    V+  RF + +A L ++T +    +  P  VR +YT     
Sbjct: 8   AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSA----VQAPLAVRALYTPCHGH 63

Query: 193 KIGSMDELEEGESYVCSSDNFFKKVEYT--KNVNPNWSVNVKTSANMKAPQSLASSNSAQ 250
            + ++ +L+    YV +    F K+ Y   +  +P        S  ++ P          
Sbjct: 64  PVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGK-----SCRLQGPPVTRHLCDGA 118

Query: 251 ARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLY 310
                    P  + + R+G        + L++  +  +E VL  +TE +KL++G V KL 
Sbjct: 119 IGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLC 178

Query: 311 TLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAG----PK 366
           TL+G  ++   +       ++A G ++F+        D     ++  +PS   G    P 
Sbjct: 179 TLEGLPLSAGKELV-TGHYYVAVGEDEFK--------DLPYLELLVPSPSLPRGCWQPPG 229

Query: 367 ASPTPQKTSAKSPGPMRRSKSPAD------SANGTSSSQLSTPKSKQSPISTPT 414
           +   P +  A+         SP +      SA      Q   P+SK   +S P+
Sbjct: 230 SKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPS 283


>gi|38569480 megakaryoblastic leukemia 2 protein [Homo sapiens]
          Length = 1049

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 7/94 (7%)

Query: 328 DVFIACGPEKFRYAQDDFSLDENECRVMKGNPSA---TAGPKASPTPQKTSAKSPGPMRR 384
           +  I  G E + + Q DFS DE+    +  +  A   + G  ASP+  K S +SP P+  
Sbjct: 168 EAIIGVGKEDYPHTQGDFSFDEDSSDALSPDQPASQESQGSAASPSEPKVS-ESPSPV-T 225

Query: 385 SKSPAD--SANGTSSSQLSTPKSKQSPISTPTSP 416
           + +PA   S + T    L TP +   P   P +P
Sbjct: 226 TNTPAQFASVSPTVPEFLKTPPTADQPPPRPAAP 259


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 37.4 bits (85), Expect = 0.027
 Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%)

Query: 356 KGNPSATAGPKASPTPQKTSAKSPGPMRRSKSP--ADSANGTSSSQLSTPKSKQSPISTP 413
           KG P+A A P+A  +P +  A + G      SP  A+    +++S  S+PK++     +P
Sbjct: 87  KGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSP 146

Query: 414 TSPGSLRKHK 423
           ++    +K K
Sbjct: 147 SNETPKKKKK 156


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 10/107 (9%)

Query: 328  DVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKS 387
            D+  A GP+   + Q   ++D      ++ N + ++  +ASPT    S  SP   +RS S
Sbjct: 3471 DLDSASGPQVSNFTQ---TVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSAS 3527

Query: 388  PADSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDS 434
            P  S  G +      PK K      P   G+ +KHK  +L  S  ++
Sbjct: 3528 P--SVPGPTK-----PKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEA 3567


>gi|239754761 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 154

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 7/72 (9%)

Query: 357 GNPSATAG------PKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPI 410
           G P  T+G      P +   P    + SPGP  + K+P  S +G S S   TP    + +
Sbjct: 7   GGPPTTSGSYTYQCPSSLDVPPLLHSPSPGPTGQDKAPLPSLSGLSPSSSPTPGCPGATL 66

Query: 411 -STPTSPGSLRK 421
            ++P  PG  RK
Sbjct: 67  GASPLLPGGSRK 78


>gi|239749289 PREDICTED: hypothetical protein XP_002346983 [Homo
           sapiens]
          Length = 154

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 7/72 (9%)

Query: 357 GNPSATAG------PKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPI 410
           G P  T+G      P +   P    + SPGP  + K+P  S +G S S   TP    + +
Sbjct: 7   GGPPTTSGSYTYQCPSSLDVPPLLHSPSPGPTGQDKAPLPSLSGLSPSSSPTPGCPGATL 66

Query: 411 -STPTSPGSLRK 421
            ++P  PG  RK
Sbjct: 67  GASPLLPGGSRK 78


>gi|239743379 PREDICTED: hypothetical protein XP_002342845 [Homo
           sapiens]
          Length = 154

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 7/72 (9%)

Query: 357 GNPSATAG------PKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPI 410
           G P  T+G      P +   P    + SPGP  + K+P  S +G S S   TP    + +
Sbjct: 7   GGPPTTSGSYTYQCPSSLDVPPLLHSPSPGPTGQDKAPLPSLSGLSPSSSPTPGCPGATL 66

Query: 411 -STPTSPGSLRK 421
            ++P  PG  RK
Sbjct: 67  GASPLLPGGSRK 78


>gi|239509073 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 154

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 7/72 (9%)

Query: 357 GNPSATAG------PKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPI 410
           G P  T+G      P +   P    + SPGP  + K+P  S +G S S   TP    + +
Sbjct: 7   GGPPTTSGSYTYQCPSSLDVPPLLHSPSPGPTGQDKAPLPSLSGLSPSSSPTPGCPGATL 66

Query: 411 -STPTSPGSLRK 421
            ++P  PG  RK
Sbjct: 67  GASPLLPGGSRK 78


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 36.2 bits (82), Expect = 0.061
 Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 16/83 (19%)

Query: 356  KGNPSATAGPKASPTP-------QKTSAKSPGPMRRSKSPA---DSANGTSSSQLSTPKS 405
            KG P AT+ PK +PTP        K S  +P P      PA    S  GT +   +TP S
Sbjct: 1298 KGGP-ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS 1356

Query: 406  KQSPIST-----PTSPGSLRKHK 423
            K  P +      PT P +   HK
Sbjct: 1357 KGGPTTPSSKEGPTPPAATPSHK 1379



 Score = 35.8 bits (81), Expect = 0.080
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 5/64 (7%)

Query: 356  KGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKS-KQSPISTPT 414
            KG P AT  PK +PTP   +  SP   + S +      G S+   +TP S K SP +TP 
Sbjct: 997  KGGP-ATPSPKGAPTPPAVTPPSP---KGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052

Query: 415  SPGS 418
              G+
Sbjct: 1053 PKGA 1056



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 10/70 (14%)

Query: 356  KGNPSATAGPKASPTPQKTSAKSPG--PMRRSKSPADSANGTSSSQ-------LSTPKSK 406
            KG+P  T  PK +PTP   +  SP   P   + +P+     T+ S         +TP  K
Sbjct: 1321 KGSPG-TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK 1379

Query: 407  QSPISTPTSP 416
              P  TP SP
Sbjct: 1380 GGPAMTPPSP 1389



 Score = 33.1 bits (74), Expect = 0.52
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)

Query: 356  KGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTS 415
            KG P AT  PK +PTP   +A  P P     +P+     T  + ++ P  K SP +TP  
Sbjct: 974  KGGP-ATPSPKGAPTP--PAATPPSPKGGPATPSPKGAPTPPA-VTPPSPKGSPAATPFP 1029

Query: 416  PGS 418
             G+
Sbjct: 1030 KGA 1032



 Score = 33.1 bits (74), Expect = 0.52
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%)

Query: 356  KGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTS 415
            KG+P+AT  PK +PT    +  SP    +      S  G  +   +TP S +   +TP+ 
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSP----KGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099

Query: 416  PGS 418
             G+
Sbjct: 1100 KGA 1102



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 5/63 (7%)

Query: 356  KGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTS 415
            KG P AT  PK +PTP   +A  P P     +P  S  G  +   +TP S +   +TP+ 
Sbjct: 951  KGGP-ATPSPKWAPTP--PAATPPSPKGGPATP--SPKGAPTPPAATPPSPKGGPATPSP 1005

Query: 416  PGS 418
             G+
Sbjct: 1006 KGA 1008



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 10/71 (14%)

Query: 356  KGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPK----------S 405
            KG+P+AT  PK + TP   +  SP     +      A  T ++ L +PK          +
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079

Query: 406  KQSPISTPTSP 416
               P +TP SP
Sbjct: 1080 PTPPAATPPSP 1090



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 10/63 (15%)

Query: 359  PSATA-GPKASPTPQKTSAKSPGPMRRSKSPADSA-NGTSSSQLSTPKSKQSPISTPTSP 416
            P+ T+  PK +PTP   +  SP      K PA  A  GT +S   TP S +    +PTSP
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSP-----EKGPATPAPKGTPTSPPVTPSSLK---DSPTSP 1654

Query: 417  GSL 419
             S+
Sbjct: 1655 ASV 1657



 Score = 30.0 bits (66), Expect = 4.4
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 5/63 (7%)

Query: 356  KGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTS 415
            KG P AT  PK +P P   +A  P P     +P     G  ++  +TP S +  ++TP  
Sbjct: 1091 KGGP-ATPSPKGAPMP--PAATPPSPKGGLATPPH--KGAPTTPAATPPSPKGGLATPPP 1145

Query: 416  PGS 418
             G+
Sbjct: 1146 KGA 1148



 Score = 30.0 bits (66), Expect = 4.4
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 4/58 (6%)

Query: 361  ATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGS 418
            AT  PK +PT    +  SP     + SP     G  ++  +TP S +  ++TP+  G+
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSP----KGAPTTPAATPPSPKGGLATPSPKGA 1240



 Score = 29.3 bits (64), Expect = 7.5
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 4/58 (6%)

Query: 361  ATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGS 418
            AT  PK +PT    +  SP     + SP     G  ++  +TP S +  ++TP+  G+
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSP----KGAPTTPAATPPSPKGGLATPSPKGA 1217


>gi|118572603 ubinuclein 1 [Homo sapiens]
          Length = 1134

 Score = 35.8 bits (81), Expect = 0.080
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 8/64 (12%)

Query: 364 GPKASPTP--------QKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTS 415
           GPKASPT          KT+AK  G    + + +   + +SSS   TP S  S +S P  
Sbjct: 829 GPKASPTQCHRSLLQLVKTAAKGQGFHPSAPATSGGLSASSSSSHKTPASSSSALSHPAK 888

Query: 416 PGSL 419
           P S+
Sbjct: 889 PHSV 892


>gi|118572601 ubinuclein 1 [Homo sapiens]
          Length = 1134

 Score = 35.8 bits (81), Expect = 0.080
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 8/64 (12%)

Query: 364 GPKASPTP--------QKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTS 415
           GPKASPT          KT+AK  G    + + +   + +SSS   TP S  S +S P  
Sbjct: 829 GPKASPTQCHRSLLQLVKTAAKGQGFHPSAPATSGGLSASSSSSHKTPASSSSALSHPAK 888

Query: 416 PGSL 419
           P S+
Sbjct: 889 PHSV 892


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 35.4 bits (80), Expect = 0.10
 Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 16/82 (19%)

Query: 353 RVMKGNPSATAG--------PKASPTPQK-TSAKSPGPMRRSKSPADSANGTSSSQLSTP 403
           R  K NPSA++G        P  SP P K   + SPGP + + S   SA+  SSS   +P
Sbjct: 321 RPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPS-VSSASWKSSS--VSP 377

Query: 404 KSKQSPISTPTS----PGSLRK 421
            S +SP ++P S    P  LRK
Sbjct: 378 SSWKSPPASPESWKSGPPELRK 399


>gi|42716277 transmembrane protein 24 [Homo sapiens]
          Length = 707

 Score = 35.4 bits (80), Expect = 0.10
 Identities = 47/223 (21%), Positives = 81/223 (36%), Gaps = 22/223 (9%)

Query: 215 KKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRK 274
           KK+E  + + P+ ++    +     P+     +S     +K  V  K  T++     P  
Sbjct: 431 KKIELDRTIMPDGTIVTTVTTVQSRPRIDGKLDSPSRSPSKVEVTEKTTTVLSESSGP-- 488

Query: 275 AVRVLLNKKTAHSFEQVLTDITEAIK-LETGVVKKLYTLDGKQVTCLHDFFGDDDVFIAC 333
                    T+HS     + ++  +  +    +++L    G+               I  
Sbjct: 489 -------SNTSHSSSPGDSHLSNGLDPVAETAIRQLTEPSGRVAKKTPT---KRSTLIIS 538

Query: 334 GPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPT--PQKTSAKSPGPMRRSKSP--A 389
           G  K   AQD+ +L       ++ +    AG    P+  P    A SPGP+    SP   
Sbjct: 539 GVSKVPIAQDELALSLGYAASLEASVQDDAGTSGGPSSPPSDPPAMSPGPLDALSSPTSV 598

Query: 390 DSANGTSSSQLSTPKSKQSPISTPTSPG-----SLRKHKDLYL 427
             A+ T+ S +S   S     S   S G     SL+ HK  +L
Sbjct: 599 QEADETTRSDISERPSVDDIESETGSTGALETRSLKDHKVSFL 641


>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
            sapiens]
          Length = 1719

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 360  SATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSS-SQLSTPKSKQSPISTPTSPGS 418
            S +A  +  P+P + S  S G  + S +PA   +G  S S   +  S  S +S+P SP S
Sbjct: 1641 SYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPAS 1700

Query: 419  LRKHKDLYL 427
             RK K L L
Sbjct: 1701 PRKTKSLSL 1709


>gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo
            sapiens]
          Length = 1638

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 360  SATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSS-SQLSTPKSKQSPISTPTSPGS 418
            S +A  +  P+P + S  S G  + S +PA   +G  S S   +  S  S +S+P SP S
Sbjct: 1560 SYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASNSSNLSSPPSPAS 1619

Query: 419  LRKHKDLYL 427
             RK K L L
Sbjct: 1620 PRKTKSLSL 1628


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 6/63 (9%)

Query: 359  PSATAGPKASPTPQKTSAKSPGP------MRRSKSPADSANGTSSSQLSTPKSKQSPIST 412
            PS  A P++SP    TSA +  P        R  +P+ +A  T+SS+L TP SK   +  
Sbjct: 1263 PSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLF 1322

Query: 413  PTS 415
            P+S
Sbjct: 1323 PSS 1325


>gi|149408146 TOX high mobility group box family member 2 isoform b
           [Homo sapiens]
          Length = 488

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 31/110 (28%), Positives = 44/110 (40%), Gaps = 5/110 (4%)

Query: 324 FGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASP---TPQKTSAKSPG 380
           FGD    +A   +     Q   S D+ E +  + NP A   P   P    P   S  +P 
Sbjct: 282 FGDVSKIVASMWDSLGEEQKQSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPS 341

Query: 381 PMRRSKSPADSAN--GTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLP 428
            ++  +S A  A+   T  S+   P    SP   P+ P S   H+ L LP
Sbjct: 342 DLQAFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLP 391


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.130    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,110,789
Number of Sequences: 37866
Number of extensions: 808406
Number of successful extensions: 6656
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 195
Number of HSP's that attempted gapping in prelim test: 5622
Number of HSP's gapped (non-prelim): 1142
length of query: 441
length of database: 18,247,518
effective HSP length: 105
effective length of query: 336
effective length of database: 14,271,588
effective search space: 4795253568
effective search space used: 4795253568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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