BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|29789373 hypothetical protein LOC92689 [Homo sapiens] (563 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|29789373 hypothetical protein LOC92689 [Homo sapiens] 1100 0.0 gi|93102375 hypothetical protein LOC10827 [Homo sapiens] 371 e-103 gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 49 9e-06 gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 49 9e-06 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 49 2e-05 gi|55741661 hypothetical protein LOC57653 [Homo sapiens] 47 4e-05 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 47 6e-05 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 47 6e-05 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 47 6e-05 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 46 8e-05 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 46 8e-05 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 46 8e-05 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 46 8e-05 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 46 1e-04 gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 45 1e-04 gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 45 1e-04 gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 45 2e-04 gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 45 2e-04 gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 45 2e-04 gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 45 2e-04 gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 45 2e-04 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 45 2e-04 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 45 2e-04 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 44 3e-04 gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 44 3e-04 gi|221219020 NYD-SP11 protein [Homo sapiens] 44 4e-04 gi|224458301 family with sequence similarity 186, member A [Homo... 44 5e-04 gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 43 7e-04 gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 43 7e-04 gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 43 7e-04 >gi|29789373 hypothetical protein LOC92689 [Homo sapiens] Length = 563 Score = 1100 bits (2845), Expect = 0.0 Identities = 563/563 (100%), Positives = 563/563 (100%) Query: 1 MSDDAGDTLATGDKAEVTEMPNSDSLPEDAEVHCDSAAVSHEPTPADPRGEGHENAAVQG 60 MSDDAGDTLATGDKAEVTEMPNSDSLPEDAEVHCDSAAVSHEPTPADPRGEGHENAAVQG Sbjct: 1 MSDDAGDTLATGDKAEVTEMPNSDSLPEDAEVHCDSAAVSHEPTPADPRGEGHENAAVQG 60 Query: 61 AGAAAIGPPVQPQDANALEPPLNRDVTEDTLAECIDSVSLEAEPRSEIPLQEQNYPAVDS 120 AGAAAIGPPVQPQDANALEPPLNRDVTEDTLAECIDSVSLEAEPRSEIPLQEQNYPAVDS Sbjct: 61 AGAAAIGPPVQPQDANALEPPLNRDVTEDTLAECIDSVSLEAEPRSEIPLQEQNYPAVDS 120 Query: 121 PPSGGGWAGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHGVNSGSSEGAQPNTENG 180 PPSGGGWAGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHGVNSGSSEGAQPNTENG Sbjct: 121 PPSGGGWAGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHGVNSGSSEGAQPNTENG 180 Query: 181 VPEITDAATDQGPAESPPTSPSSASRGMLSAITNVVQNTGKSVLTGGLDALEFIGKKTMN 240 VPEITDAATDQGPAESPPTSPSSASRGMLSAITNVVQNTGKSVLTGGLDALEFIGKKTMN Sbjct: 181 VPEITDAATDQGPAESPPTSPSSASRGMLSAITNVVQNTGKSVLTGGLDALEFIGKKTMN 240 Query: 241 VLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLS 300 VLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLS Sbjct: 241 VLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLS 300 Query: 301 HLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEE 360 HLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEE Sbjct: 301 HLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEE 360 Query: 361 KGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEK 420 KGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEK Sbjct: 361 KGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEK 420 Query: 421 EEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQ 480 EEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQ Sbjct: 421 EEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQ 480 Query: 481 DQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSVLLEGCNSTTYIQD 540 DQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSVLLEGCNSTTYIQD Sbjct: 481 DQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSVLLEGCNSTTYIQD 540 Query: 541 AFQLLLPVLQVSHIQTSCLKAQP 563 AFQLLLPVLQVSHIQTSCLKAQP Sbjct: 541 AFQLLLPVLQVSHIQTSCLKAQP 563 >gi|93102375 hypothetical protein LOC10827 [Homo sapiens] Length = 505 Score = 371 bits (953), Expect = e-103 Identities = 211/462 (45%), Positives = 300/462 (64%), Gaps = 38/462 (8%) Query: 99 SLEAEPRSEIPLQEQNYPAVDSPPSGGGWAGWGSWGKSLLSSASATV---GHGLTAVKEK 155 S + E +P+Q+ + D P + W WGSWGKS+LSSASATV G G++ V EK Sbjct: 58 SSDLETSKVLPIQDN--VSKDVPQTR--WGYWGSWGKSILSSASATVATVGQGISNVIEK 113 Query: 156 AGATLRIHGVNSGSSEGAQPNTENGVPEITDAATDQGPAESPPTSPSSASRGMLSAITNV 215 A +L I G + S+E + A + E+ +SP + + G+ S I+ Sbjct: 114 AETSLGIPGPSEISTE------------VKYVAGETNAKENENSSPVAGAFGVFSTISTA 161 Query: 216 VQNTGKSVLTGGLDALEFIGKKTMNVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQ 275 VQ+TGKSV++GGLDALEFIGKKTM+V+AE DPGFKRTK LM R +LSQ+LREAKEKE+ Sbjct: 162 VQSTGKSVISGGLDALEFIGKKTMDVIAEGDPGFKRTKGLMNRNATLSQVLREAKEKEEI 221 Query: 276 RLAQQLTME--RTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASLDGEKLELLKN 333 R + ++T+E + HYG+LFDE+QGLSHLEALE+LS ESE KV+S L SL GE+LE LK Sbjct: 222 RTSNEVTVETDKKTHYGLLFDEFQGLSHLEALEMLSQESEIKVKSILNSLSGEELETLKV 281 Query: 334 DLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAH 393 +L +K+ F+ E EE +E++G E+F + +TEL +LHV++ P+KL +A AH Sbjct: 282 ELEQLKETFSLAEFCEEEEEEKKG----DEDFTKDITELFSQLHVSSKPEKLARARNTAH 337 Query: 394 DWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAE 453 +W+ + T E EE + + + E+ +IE+++ +I SLAE Sbjct: 338 EWIRKSLT-------------KPLAENEEGEKQSEAENTEQVNKNSIEDIHAFAIRSLAE 384 Query: 454 VTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGS 513 +TA IE HK A L+LHG+++E A ++++ L ++T +C E++SLSK+FT LTT G Sbjct: 385 LTACSIELFHKTAALVLHGRKQEVTAIERSQTLSQMTIVLCKELSSLSKEFTTCLTTAGV 444 Query: 514 NKKAEVLNPMISSVLLEGCNSTTYIQDAFQLLLPVLQVSHIQ 555 + A+VLNP+I++V LE NS +YIQDAFQLLLPVL++S I+ Sbjct: 445 KEMADVLNPLITAVFLEASNSASYIQDAFQLLLPVLEISLIE 486 >gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin repeats isoform 2 [Homo sapiens] Length = 1403 Score = 49.3 bits (116), Expect = 9e-06 Identities = 67/282 (23%), Positives = 122/282 (43%), Gaps = 38/282 (13%) Query: 249 FKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEIL 308 F K L ++TV + K E +R + T E L +Y + +++ E L Sbjct: 1025 FTLQKDLRDKTVLIE------KSHEMERALSRKTDELNKQLKDLSQKYTEVKNVK--EKL 1076 Query: 309 SNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKE-----LEN--EENQEEQGLEEK 361 E+ + LA + LL+ + ++ + A K+ +EN EE + Q EK Sbjct: 1077 VEENAKQTSEILAVQN-----LLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEK 1131 Query: 362 GEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKE 421 ++ L +LL ++ P + +K A E++ ++ + + EE K E+ Sbjct: 1132 EQQTVTKLHQLLENQKNSSVPLAEHLQIKEAF---EKEVGIIKASLREKEEESQNKMEEV 1188 Query: 422 EKSQ-DPQEDKKEEKKTKTIEEVYMSS-----------IESLAEVTARCIEQLHKVAELI 469 K Q + Q K+ KK +T E V +S I SL E A + +V E + Sbjct: 1189 SKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEV 1248 Query: 470 LHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTV 511 LH +++E A+D+ ++ L ++ E+ ++ SLTT+ Sbjct: 1249 LHAKKKEISAKDEKEL---LHFSIEQEIKDQKERCDKSLTTI 1287 Score = 42.0 bits (97), Expect = 0.002 Identities = 66/285 (23%), Positives = 114/285 (40%), Gaps = 44/285 (15%) Query: 250 KRTKTLMERTVSLSQMLREAKEK--EKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEI 307 K L V L + L E K+K E Q LT E T M+ ++Y + E +++ Sbjct: 798 KEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKM 857 Query: 308 LSNESESKVQSFLASLDGEKLELLKNDLISIKDI--FAAKELENEENQEEQGLEEKGEEF 365 N++ +K L + +K E + + + IKD + LEN +NQ + E Sbjct: 858 TLNDTLAKTNRELLDVK-KKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHE 916 Query: 366 ARM--LTELLFELHVAATPDKLN---------------KAMKRAHDWVEEDQTVVSVDVA 408 A+M L++ + ++ + N KA K+ D ++E V + Sbjct: 917 AKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIV 976 Query: 409 KVSEEE-----TKKEEKEEKSQDPQE---DKKEEKKTKTIEEVYMSSIESLAEVTARCIE 460 E E T+KE K++ S+ Q+ ++E KK K + I +L + Sbjct: 977 SFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQ-------K 1029 Query: 461 QLHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFT 505 L LI E E + L + T + ++ LS+K+T Sbjct: 1030 DLRDKTVLIEKSHEME-------RALSRKTDELNKQLKDLSQKYT 1067 Score = 41.6 bits (96), Expect = 0.002 Identities = 63/307 (20%), Positives = 124/307 (40%), Gaps = 65/307 (21%) Query: 256 MERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLF--DEYQGLSHLEALEILSNESE 313 +++ +S+ +M RE K ++ + Q E +A + ++++ + LSNE Sbjct: 578 LQKELSMCEMEREKKGRKVTEMEGQ-AKELSAKLALSIPAEKFENMK-----SSLSNEVN 631 Query: 314 SKVQSFLASLDGE------KLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFAR 367 K + L ++ E ++ LK +L ++K A E Q + LE+K E + Sbjct: 632 EKAKK-LVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGK 690 Query: 368 MLTE----------------------------LLFELHVAATPDKLNKAMKRAHDWVEED 399 +TE L E+ P K+++ MK++HD + +D Sbjct: 691 KITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDD 750 Query: 400 QTVVSVDVA-KVSEEETKKE----EKEEKSQDPQE-------DKKEEKKTKTIEEVYMSS 447 +DV K +E++ + E E + S+D +K EK+ ++ + Sbjct: 751 LNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVEL 810 Query: 448 IESLAEVTARCIEQLHKVAEL---------ILHGQEEEKPAQDQAKVLIKLTTAMCN-EV 497 + L+E+ +C E K+ L ++ Q ++ K+ + T A N E+ Sbjct: 811 KKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNREL 870 Query: 498 ASLSKKF 504 + KKF Sbjct: 871 LDVKKKF 877 >gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin repeats isoform 1 [Homo sapiens] Length = 1416 Score = 49.3 bits (116), Expect = 9e-06 Identities = 67/282 (23%), Positives = 122/282 (43%), Gaps = 38/282 (13%) Query: 249 FKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEIL 308 F K L ++TV + K E +R + T E L +Y + +++ E L Sbjct: 1038 FTLQKDLRDKTVLIE------KSHEMERALSRKTDELNKQLKDLSQKYTEVKNVK--EKL 1089 Query: 309 SNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKE-----LEN--EENQEEQGLEEK 361 E+ + LA + LL+ + ++ + A K+ +EN EE + Q EK Sbjct: 1090 VEENAKQTSEILAVQN-----LLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEK 1144 Query: 362 GEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKE 421 ++ L +LL ++ P + +K A E++ ++ + + EE K E+ Sbjct: 1145 EQQTVTKLHQLLENQKNSSVPLAEHLQIKEAF---EKEVGIIKASLREKEEESQNKMEEV 1201 Query: 422 EKSQ-DPQEDKKEEKKTKTIEEVYMSS-----------IESLAEVTARCIEQLHKVAELI 469 K Q + Q K+ KK +T E V +S I SL E A + +V E + Sbjct: 1202 SKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEV 1261 Query: 470 LHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTV 511 LH +++E A+D+ ++ L ++ E+ ++ SLTT+ Sbjct: 1262 LHAKKKEISAKDEKEL---LHFSIEQEIKDQKERCDKSLTTI 1300 Score = 42.0 bits (97), Expect = 0.002 Identities = 66/285 (23%), Positives = 114/285 (40%), Gaps = 44/285 (15%) Query: 250 KRTKTLMERTVSLSQMLREAKEK--EKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEI 307 K L V L + L E K+K E Q LT E T M+ ++Y + E +++ Sbjct: 811 KEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKM 870 Query: 308 LSNESESKVQSFLASLDGEKLELLKNDLISIKDI--FAAKELENEENQEEQGLEEKGEEF 365 N++ +K L + +K E + + + IKD + LEN +NQ + E Sbjct: 871 TLNDTLAKTNRELLDVK-KKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHE 929 Query: 366 ARM--LTELLFELHVAATPDKLN---------------KAMKRAHDWVEEDQTVVSVDVA 408 A+M L++ + ++ + N KA K+ D ++E V + Sbjct: 930 AKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIV 989 Query: 409 KVSEEE-----TKKEEKEEKSQDPQE---DKKEEKKTKTIEEVYMSSIESLAEVTARCIE 460 E E T+KE K++ S+ Q+ ++E KK K + I +L + Sbjct: 990 SFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQ-------K 1042 Query: 461 QLHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFT 505 L LI E E + L + T + ++ LS+K+T Sbjct: 1043 DLRDKTVLIEKSHEME-------RALSRKTDELNKQLKDLSQKYT 1080 Score = 41.6 bits (96), Expect = 0.002 Identities = 63/307 (20%), Positives = 124/307 (40%), Gaps = 65/307 (21%) Query: 256 MERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLF--DEYQGLSHLEALEILSNESE 313 +++ +S+ +M RE K ++ + Q E +A + ++++ + LSNE Sbjct: 591 LQKELSMCEMEREKKGRKVTEMEGQ-AKELSAKLALSIPAEKFENMK-----SSLSNEVN 644 Query: 314 SKVQSFLASLDGE------KLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFAR 367 K + L ++ E ++ LK +L ++K A E Q + LE+K E + Sbjct: 645 EKAKK-LVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGK 703 Query: 368 MLTE----------------------------LLFELHVAATPDKLNKAMKRAHDWVEED 399 +TE L E+ P K+++ MK++HD + +D Sbjct: 704 KITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDD 763 Query: 400 QTVVSVDVA-KVSEEETKKE----EKEEKSQDPQE-------DKKEEKKTKTIEEVYMSS 447 +DV K +E++ + E E + S+D +K EK+ ++ + Sbjct: 764 LNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVEL 823 Query: 448 IESLAEVTARCIEQLHKVAEL---------ILHGQEEEKPAQDQAKVLIKLTTAMCN-EV 497 + L+E+ +C E K+ L ++ Q ++ K+ + T A N E+ Sbjct: 824 KKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNREL 883 Query: 498 ASLSKKF 504 + KKF Sbjct: 884 LDVKKKF 890 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 48.5 bits (114), Expect = 2e-05 Identities = 51/220 (23%), Positives = 100/220 (45%), Gaps = 13/220 (5%) Query: 270 KEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASLDGEKLE 329 ++K+ R ++LT ER A + + Y+ E L+ E +K+Q L ++ EK E Sbjct: 248 QKKKADRYIEELTKERDA---LSLELYRNTITDEELK----EKNAKLQEKLQLVESEKSE 300 Query: 330 LLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKA- 388 + N + +K +L + Q + + G+E + +L ++ ++LN+ Sbjct: 301 IQLN-VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 359 Query: 389 ---MKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDK-KEEKKTKTIEEVY 444 M R + ++E + + K+ E+E K E+EEK + +E ++E+K + EE+ Sbjct: 360 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 419 Query: 445 MSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAK 484 E + E+ K+ EL E+EK + + K Sbjct: 420 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459 Score = 38.9 bits (89), Expect = 0.013 Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 16/175 (9%) Query: 345 KELENEENQEEQGLEEKG----EEFARMLTELLF-ELHVAATPDKLNKAMKRAHDWVE-- 397 +E E + QEE +E+ EE R ++ E + +K+ + ++ HD E Sbjct: 514 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKI 573 Query: 398 -EDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKE--------EKKTKTIEEVYMSSI 448 E + V K+ E+E K E+EEK ++ +E +E E+K EE Sbjct: 574 REQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 633 Query: 449 ESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKK 503 E + + EQ K+ E +E+E+ Q+Q + + + MC + + ++ Sbjct: 634 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 688 Score = 37.4 bits (85), Expect = 0.037 Identities = 33/160 (20%), Positives = 72/160 (45%), Gaps = 17/160 (10%) Query: 348 ENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKA---MKRAHDWVEEDQTVVS 404 E + + +E+ + E+ E+ R E + +K+ + ++ + +E + + Sbjct: 563 EEKMHDQEEKIREQEEKVWRQ------EEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616 Query: 405 VDVAKVSEEETKKEEKEEKSQDPQED-KKEEKKTKTIEEVYMSSIESLAEVTARCIEQLH 463 K+ E+E K +E+EEK + +E +++EKK + EE E + E + EQ Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 676 Query: 464 KVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKK 503 K+ E +E+ Q+Q + + + M + L ++ Sbjct: 677 KMCE-------QEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709 Score = 36.2 bits (82), Expect = 0.082 Identities = 45/247 (18%), Positives = 108/247 (43%), Gaps = 13/247 (5%) Query: 249 FKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEIL 308 +++ + + E + + + +E+E++ Q+ M R M++++ + + E + + Sbjct: 364 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE--MMWEKEEKMRRQEEM-MW 420 Query: 309 SNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKEL--------ENEENQEEQGLEE 360 E + + Q + EK+ L+ + + I +E E E+ QE++ Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 480 Query: 361 KGEEFARMLTELLFELH--VAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKE 418 + EE R E + E + +K+++ K + ++Q + K+ E+E Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540 Query: 419 EKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKP 478 +KE+ + ++ +K+E+K EE E + E + Q K+ E +E+E+ Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600 Query: 479 AQDQAKV 485 ++Q ++ Sbjct: 601 IREQEEM 607 Score = 32.7 bits (73), Expect = 0.91 Identities = 21/104 (20%), Positives = 50/104 (48%), Gaps = 10/104 (9%) Query: 346 ELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSV 405 E E + ++E+ ++E+ E+ R ++ + K ++ + + E + ++ Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQ----------EKKIREQEEKIREQEEMMQE 666 Query: 406 DVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIE 449 K+ E+E K E+EEK Q+ +E + +++ +EV + E Sbjct: 667 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 710 Score = 32.0 bits (71), Expect = 1.6 Identities = 28/121 (23%), Positives = 55/121 (45%), Gaps = 9/121 (7%) Query: 348 ENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDV 407 E EE +EQ E+ GE+ +M + + + M+R + + E + + Sbjct: 603 EQEEMTQEQE-EKMGEQEEKMCEQ-------EEKMQEQEEKMRRQEEKIREQEKKIREQE 654 Query: 408 AKVSE-EETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVA 466 K+ E EE +E++E+ + ++ ++E+K + EE E + E R +Q K+ Sbjct: 655 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714 Query: 467 E 467 E Sbjct: 715 E 715 >gi|55741661 hypothetical protein LOC57653 [Homo sapiens] Length = 1646 Score = 47.4 bits (111), Expect = 4e-05 Identities = 48/186 (25%), Positives = 83/186 (44%), Gaps = 22/186 (11%) Query: 268 EAKEKEKQRLAQQLTMERTAHYGMLFDEYQ---GLSHLEALEILSNESESKVQSFLASLD 324 EA EK Q+ ++L ++ + M E G S ++E + E++ +++SF+ Sbjct: 793 EAHEKPSQKRVKKLRKKQGSKEDMTRSEESISSGTSTARSVEEVEEENDQEMESFITE-- 850 Query: 325 GEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDK 384 E L K + K ++ + QGLEE E L L E +V +K Sbjct: 851 -EVLGQQKKSPLHAK-------MDESKEGSIQGLEEMQVEREGSLNPSLNEENVKGQGEK 902 Query: 385 LNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVY 444 ++ EED+ + K+ EE+ +KE +EE Q+ +EE K + +EE+Y Sbjct: 903 KEESE-------EEDEKEEEEEEEKLEEEKEEKEAQEE--QESLSVGEEEDKEEGLEEIY 953 Query: 445 MSSIES 450 +ES Sbjct: 954 YEDMES 959 Score = 31.2 bits (69), Expect = 2.6 Identities = 31/147 (21%), Positives = 68/147 (46%), Gaps = 13/147 (8%) Query: 312 SESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTE 371 S+ +V+ L G K ++ +++ A+ +E E + +Q +E E E Sbjct: 799 SQKRVKK-LRKKQGSKEDMTRSEESISSGTSTARSVEEVEEENDQEMESFITE------E 851 Query: 372 LLFELHVAATPDKLNKAMKRAHDWVEEDQTV------VSVDVAKVSEEETKKEEKEEKSQ 425 +L + + K++++ + + +EE Q S++ V + KKEE EE+ + Sbjct: 852 VLGQQKKSPLHAKMDESKEGSIQGLEEMQVEREGSLNPSLNEENVKGQGEKKEESEEEDE 911 Query: 426 DPQEDKKEEKKTKTIEEVYMSSIESLA 452 +E+++E+ + + E+ ESL+ Sbjct: 912 KEEEEEEEKLEEEKEEKEAQEEQESLS 938 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 46.6 bits (109), Expect = 6e-05 Identities = 38/180 (21%), Positives = 78/180 (43%), Gaps = 21/180 (11%) Query: 345 KELENEENQEEQGLEEKG----EEFARMLTELLFELHVAATPDKLNKAMKRAHD------ 394 +E E + QEE +E+ EE R ++ + + +K+ + ++ HD Sbjct: 453 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIR 512 Query: 395 ------W-----VEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEV 443 W + E + + K+ E+E +E+EEK + +E +E++K + EE Sbjct: 513 EQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK 572 Query: 444 YMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKK 503 E + E + EQ K+ E +E+E+ Q+Q + + + MC + + ++ Sbjct: 573 IREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632 Score = 45.8 bits (107), Expect = 1e-04 Identities = 48/220 (21%), Positives = 101/220 (45%), Gaps = 13/220 (5%) Query: 270 KEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASLDGEKLE 329 ++K+ R ++LT ER A + + Y+ E L+ E +K+Q L ++ EK E Sbjct: 187 QKKKADRYIEELTKERDA---LSLELYRNTITDEELK----EKNAKLQEKLQLVESEKSE 239 Query: 330 LLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKA- 388 + N + +K +L + Q + + G+E + +L ++ ++LN+ Sbjct: 240 IQLN-VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298 Query: 389 ---MKRAHDWVEEDQTVVSVDVAKVSEEETK-KEEKEEKSQDPQEDKKEEKKTKTIEEVY 444 M R + ++E + + K+ E+E K +E++E+ + + ++E+K + EE+ Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358 Query: 445 MSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAK 484 E + + E+ K+ EL E+EK + + K Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398 Score = 39.7 bits (91), Expect = 0.007 Identities = 46/234 (19%), Positives = 108/234 (46%), Gaps = 20/234 (8%) Query: 249 FKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEIL 308 +++ + + E + + + +E+E++ Q+ M R M++++ + + E + Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE--MMWEKEEKMRRQEEMMWE 360 Query: 309 SNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARM 368 E +++ + + EK+ L+ + + I +E EE + + E++ E+ A+M Sbjct: 361 KEEKMRRLEEMMWEKE-EKIRELEEKMHEQEKIREQEEKRQEEEKIREQ-EKRQEQEAKM 418 Query: 369 LTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQ 428 + E + +K+ + K+ W +E+ K+ E+E +EE EK Q+ + Sbjct: 419 WRQ---EEKIREQEEKIREQEKKM--WRQEE---------KIHEQEKIREE--EKRQEQE 462 Query: 429 EDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQ 482 E ++E+K + EE++ + + R E+ E +H QEE+ Q++ Sbjct: 463 EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516 Score = 35.4 bits (80), Expect = 0.14 Identities = 27/129 (20%), Positives = 57/129 (44%), Gaps = 14/129 (10%) Query: 389 MKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSI 448 ++ + + E + + + E+E K E+EEK Q+ ++ +++E+K + EE Sbjct: 525 IREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584 Query: 449 ESLAEVTARCIEQLHKVAEL--ILHGQEE------------EKPAQDQAKVLIKLTTAMC 494 E + E + EQ K+ E ++ QEE E+ Q+Q + + + M Sbjct: 585 EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 644 Query: 495 NEVASLSKK 503 + L ++ Sbjct: 645 EQEVRLRQQ 653 Score = 35.0 bits (79), Expect = 0.18 Identities = 29/142 (20%), Positives = 68/142 (47%), Gaps = 10/142 (7%) Query: 345 KELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVS 404 +E E + ++E+ ++E+ E+ ++ + + +K+ + ++ + E + + Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK----IREQKEKIR 588 Query: 405 VDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHK 464 K+ E+E K E+EE Q+ QE+K E++ K E+ E + E + Q K Sbjct: 589 EQEEKIWEQEEKIREQEEMMQE-QEEKMWEQEEKMCEQE-----EKMQEQEEKMRRQEEK 642 Query: 465 VAELILHGQEEEKPAQDQAKVL 486 + E + +++E+ Q+ + L Sbjct: 643 MWEQEVRLRQQEEKMQEHQEHL 664 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 46.6 bits (109), Expect = 6e-05 Identities = 60/292 (20%), Positives = 121/292 (41%), Gaps = 37/292 (12%) Query: 216 VQNTGKSVLTGGLDALEFIGKKTMNVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQ 275 +++ G S + D ++ KK + E + F++ + + + L ++ + K E Sbjct: 116 IEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQ-KRPENS 174 Query: 276 RLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSN--------ESESKVQSFLASLDGEK 327 L + L + G ++ +LE+ N E +++Q L ++ EK Sbjct: 175 LLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEK 234 Query: 328 LELLKNDLISIKDIFAAKELENEENQ-EEQGLEEKGEEFARMLTELLFELHVAATPDKL- 385 E+ N +KD+ ++LE + +Q L+ + + + L + +L ++L Sbjct: 235 SEIQLN----VKDL--KRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288 Query: 386 -------NKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQD------PQEDK- 431 + M R + ++E + + K+ E+E K +EEK + QEDK Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348 Query: 432 -KEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQ 482 ++E+K + EE E + + EQ K+ E QEEE Q++ Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQE-----QEEEMWRQEE 395 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 4/125 (3%) Query: 345 KELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVS 404 +E+E + +EE+ ++E+ E+ R ++ + +KL K ++ W +E++ Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKI--WEQEEKMWRQ 508 Query: 405 VDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHK 464 + K+ E+E K +E+EEK Q +E +E++ +E M E + + +L + Sbjct: 509 EE--KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQ 566 Query: 465 VAELI 469 AEL+ Sbjct: 567 KAELL 571 Score = 36.2 bits (82), Expect = 0.082 Identities = 35/159 (22%), Positives = 74/159 (46%), Gaps = 12/159 (7%) Query: 326 EKLELLKNDLISIKDIFAAKELENEEN--QEEQGLEEKGEEFARMLTELLFELHVAATPD 383 EK++ + ++ ++ +E + +E ++E+ + E+ E+ E+ + + Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQ------EE 434 Query: 384 KLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEV 443 K+ + + D E+ + V K+ EEE K +E+EEK Q +E +E+++ +E Sbjct: 435 KIRELEEMMQDQEEKLREVEE----KMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490 Query: 444 YMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQ 482 + E + E + Q K+ E QE+E+ Q Q Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529 Score = 35.4 bits (80), Expect = 0.14 Identities = 28/135 (20%), Positives = 60/135 (44%), Gaps = 10/135 (7%) Query: 348 ENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDV 407 E + ++++ + E+ EE R ++ +L + M+ + + E + + + Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIR----------ELEEMMQDQEEKLREVEEKMQEEE 461 Query: 408 AKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAE 467 K+ E+E K + +EEK Q+ +E ++K EE E + + EQ K+ E Sbjct: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521 Query: 468 LILHGQEEEKPAQDQ 482 Q +E+ ++Q Sbjct: 522 QEEKMQRQEEKMREQ 536 Score = 33.5 bits (75), Expect = 0.53 Identities = 29/138 (21%), Positives = 56/138 (40%), Gaps = 12/138 (8%) Query: 348 ENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDV 407 E + ++++ ++E+ EE R E + +K + M R + E + Sbjct: 373 EEKIREQDEKIQEQEEEMWRQ------EEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426 Query: 408 AKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAE 467 ++ +E K E EE QD +E+K + +EE E + E + Q K+ E Sbjct: 427 EEMWRQEEKIRELEEMMQD------QEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480 Query: 468 LILHGQEEEKPAQDQAKV 485 +EK + + K+ Sbjct: 481 QEEKTWRQEKLLKQEEKI 498 Score = 33.5 bits (75), Expect = 0.53 Identities = 27/133 (20%), Positives = 59/133 (44%), Gaps = 6/133 (4%) Query: 350 EENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAK 409 E+ +E EEK E M+ + +L ++ + M+ + ++E + + K Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLR------EVEEKMQEEEEKMQEQEEKIQRQEEK 477 Query: 410 VSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELI 469 + E+E K +E+ + ++ ++E+K EE E + E + Q K+ E Sbjct: 478 IQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537 Query: 470 LHGQEEEKPAQDQ 482 + ++E+ Q+Q Sbjct: 538 VRLWQQEEKMQEQ 550 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 46.6 bits (109), Expect = 6e-05 Identities = 59/251 (23%), Positives = 104/251 (41%), Gaps = 32/251 (12%) Query: 261 SLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEY--------QGLSHLEALEILSNES 312 S+ + E +EK +Q+ T+ + G + E QG + E + E Sbjct: 202 SIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEED 261 Query: 313 ESKVQSFLASLDGEKLELLKNDL----------ISIKDIFAAKELENEENQEEQGLEEK- 361 + + ++ A L+ E+ E +K + I ++ AA+E E E +E + + E+ Sbjct: 262 KERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEE 321 Query: 362 ---GEEFARMLTELLFELHVAATPDKLNKAMKRAHDW-----VEEDQTVVSVDVAKVSEE 413 EE R+ E E A ++ + KRA + EE + A+ EE Sbjct: 322 KRAAEERQRIKEE---EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE 378 Query: 414 ETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQ 473 E K E++++++ +E K ++TK E IE + E K+ +L Q Sbjct: 379 EKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQED--KLQTAVLKKQ 436 Query: 474 EEEKPAQDQAK 484 EEK + QAK Sbjct: 437 GEEKGTKVQAK 447 Score = 33.5 bits (75), Expect = 0.53 Identities = 52/264 (19%), Positives = 111/264 (42%), Gaps = 38/264 (14%) Query: 257 ERTVSLSQMLREAKEKEKQRLAQQLTME----------RTAHYGMLFDEYQGLSHLEALE 306 ER L + RE E +R+A Q + R A L + + S + + Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64 Query: 307 ILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFA 366 + +++ V A ++ +D + + A +E E + + ++ LE + +EF Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARRE-ERRQKRLQEALERQ-KEFD 122 Query: 367 RMLTELLFELHVAA---------TPDKLNKAMKRAHDWVEEDQTVVSVDVAKVS---EEE 414 +T+ L T +K K+ R + E+ V+ K EE Sbjct: 123 PTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEE 182 Query: 415 TKKEEKEEKSQDPQEDKK------------EEKKTKTIEEVYMSSIES--LAEVTARCIE 460 KKE+KE++ ++ ++ K+ EEK T++ EE + S+++ ++ + E Sbjct: 183 NKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEE 242 Query: 461 QLHKVAELILHGQEEEKPAQDQAK 484 + + ++ I H ++ E+ +++A+ Sbjct: 243 EREQGSDEISHHEKMEEEDKERAE 266 Score = 30.4 bits (67), Expect = 4.5 Identities = 43/189 (22%), Positives = 81/189 (42%), Gaps = 21/189 (11%) Query: 257 ERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESES-- 314 E+ + + REA+E+E+ R ++ R A E + + E I E + Sbjct: 299 EKAAAQERERREAEERERMREEEK----RAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 354 Query: 315 -----KVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARML 369 K + A+ + ++ + + +++ K+LE E+ Q + KGE+ + + Sbjct: 355 ERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLE-EKKHAMQETKIKGEKVEQKI 413 Query: 370 TELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEE------ETKKEEKEEK 423 E + A DKL A+ + EE T V K+ E+ E K+EK +K Sbjct: 414 -EGKWVNEKKAQEDKLQTAVLKKQG--EEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 470 Query: 424 SQDPQEDKK 432 ++P+E+ K Sbjct: 471 DKEPKEEVK 479 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 46.2 bits (108), Expect = 8e-05 Identities = 56/223 (25%), Positives = 103/223 (46%), Gaps = 26/223 (11%) Query: 232 EFIGKKTMNVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGM 291 E I T N+ E + TK + +S++ K++EK R Q+L + G Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR--QELEKLKRKLEGD 1063 Query: 292 LFDEYQGLSHLEA----LEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFA---- 343 D ++ ++ L+A L++ + E ++Q+ LA LD E + N L I+++ Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE-IAQKNNALKKIRELEGHISD 1122 Query: 344 -AKELENEE---NQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEED 399 ++L++E N+ E+ + GEE + TEL L AT +L KR E++ Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR--AKR-----EQE 1175 Query: 400 QTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEE 442 TV+ K +EET+ E + + + + E+ T+ +E+ Sbjct: 1176 VTVLK----KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1214 Score = 44.7 bits (104), Expect = 2e-04 Identities = 80/351 (22%), Positives = 141/351 (40%), Gaps = 51/351 (14%) Query: 150 TAVKEKA--GATLRIHGVNSGSSEGAQPNTENGVPEITDAATDQGPAESPPTSPSSASRG 207 T KE A LR+ G E + E V E+ +D +R Sbjct: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD-----------GERARA 1276 Query: 208 MLSAITNVVQNTGKSVLTGGLDALEFIGKKTMNVLAESDPGFKRTKTLME----RTVSLS 263 L+ + +QN +SV TG L+ E K +A + T+ L++ + +++S Sbjct: 1277 ELNDKVHKLQNEVESV-TGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVS 1335 Query: 264 QMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASL 323 LR+ +E E+ L QL E A + H+ L I ++S+ K+Q F +++ Sbjct: 1336 TKLRQLEE-ERNSLQDQLDEEMEAKQNLE-------RHISTLNIQLSDSKKKLQDFASTV 1387 Query: 324 DGEKLELLKNDLISIKDIFAAKELENEENQEEQG------LEEKGEEFARMLTELLFEL- 376 E LE K KE+EN Q E+ LE+ + L +L+ +L Sbjct: 1388 --EALEEGKKRF--------QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437 Query: 377 HVAATPDKLNKAMKRAHDWVEEDQTVVSVDV-------AKVSEEETKKEEKEEKSQDPQE 429 + L K ++ + E++ + S A+ E+ETK ++ E Sbjct: 1438 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1497 Query: 430 DKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQ 480 K+E ++T + + M + S + + + +L K ++ L Q EE Q Sbjct: 1498 AKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK-SKRALETQMEEMKTQ 1547 Score = 37.7 bits (86), Expect = 0.028 Identities = 43/197 (21%), Positives = 87/197 (44%), Gaps = 16/197 (8%) Query: 309 SNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARM 368 + E + K ++ L L+ + +L + + + + A EL E + L K +E + Sbjct: 864 TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEI 923 Query: 369 LTELLFELH--------VAATPDKLNKAMKRAHDWVEEDQTV-VSVDVAKVSEEETKKEE 419 L E+ L + A K+ + M + +EE++ + + KV+ E K+ Sbjct: 924 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 983 Query: 420 KEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARC-----IEQLHK--VAELILHG 472 ++E ++ K K+ K +EE +LAE + ++ H+ ++EL + Sbjct: 984 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1043 Query: 473 QEEEKPAQDQAKVLIKL 489 ++EEK Q+ K+ KL Sbjct: 1044 KKEEKSRQELEKLKRKL 1060 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 46.2 bits (108), Expect = 8e-05 Identities = 56/223 (25%), Positives = 103/223 (46%), Gaps = 26/223 (11%) Query: 232 EFIGKKTMNVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGM 291 E I T N+ E + TK + +S++ K++EK R Q+L + G Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR--QELEKLKRKLEGD 1070 Query: 292 LFDEYQGLSHLEA----LEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFA---- 343 D ++ ++ L+A L++ + E ++Q+ LA LD E + N L I+++ Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE-IAQKNNALKKIRELEGHISD 1129 Query: 344 -AKELENEE---NQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEED 399 ++L++E N+ E+ + GEE + TEL L AT +L KR E++ Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR--AKR-----EQE 1182 Query: 400 QTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEE 442 TV+ K +EET+ E + + + + E+ T+ +E+ Sbjct: 1183 VTVLK----KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1221 Score = 44.7 bits (104), Expect = 2e-04 Identities = 80/351 (22%), Positives = 141/351 (40%), Gaps = 51/351 (14%) Query: 150 TAVKEKA--GATLRIHGVNSGSSEGAQPNTENGVPEITDAATDQGPAESPPTSPSSASRG 207 T KE A LR+ G E + E V E+ +D +R Sbjct: 1235 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD-----------GERARA 1283 Query: 208 MLSAITNVVQNTGKSVLTGGLDALEFIGKKTMNVLAESDPGFKRTKTLME----RTVSLS 263 L+ + +QN +SV TG L+ E K +A + T+ L++ + +++S Sbjct: 1284 ELNDKVHKLQNEVESV-TGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVS 1342 Query: 264 QMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASL 323 LR+ +E E+ L QL E A + H+ L I ++S+ K+Q F +++ Sbjct: 1343 TKLRQLEE-ERNSLQDQLDEEMEAKQNLE-------RHISTLNIQLSDSKKKLQDFASTV 1394 Query: 324 DGEKLELLKNDLISIKDIFAAKELENEENQEEQG------LEEKGEEFARMLTELLFEL- 376 E LE K KE+EN Q E+ LE+ + L +L+ +L Sbjct: 1395 --EALEEGKKRF--------QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1444 Query: 377 HVAATPDKLNKAMKRAHDWVEEDQTVVSVDV-------AKVSEEETKKEEKEEKSQDPQE 429 + L K ++ + E++ + S A+ E+ETK ++ E Sbjct: 1445 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1504 Query: 430 DKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQ 480 K+E ++T + + M + S + + + +L K ++ L Q EE Q Sbjct: 1505 AKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK-SKRALETQMEEMKTQ 1554 Score = 37.7 bits (86), Expect = 0.028 Identities = 43/197 (21%), Positives = 87/197 (44%), Gaps = 16/197 (8%) Query: 309 SNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARM 368 + E + K ++ L L+ + +L + + + + A EL E + L K +E + Sbjct: 871 TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEI 930 Query: 369 LTELLFELH--------VAATPDKLNKAMKRAHDWVEEDQTV-VSVDVAKVSEEETKKEE 419 L E+ L + A K+ + M + +EE++ + + KV+ E K+ Sbjct: 931 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 990 Query: 420 KEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARC-----IEQLHK--VAELILHG 472 ++E ++ K K+ K +EE +LAE + ++ H+ ++EL + Sbjct: 991 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1050 Query: 473 QEEEKPAQDQAKVLIKL 489 ++EEK Q+ K+ KL Sbjct: 1051 KKEEKSRQELEKLKRKL 1067 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 46.2 bits (108), Expect = 8e-05 Identities = 56/223 (25%), Positives = 103/223 (46%), Gaps = 26/223 (11%) Query: 232 EFIGKKTMNVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGM 291 E I T N+ E + TK + +S++ K++EK R Q+L + G Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR--QELEKLKRKLEGD 1070 Query: 292 LFDEYQGLSHLEA----LEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFA---- 343 D ++ ++ L+A L++ + E ++Q+ LA LD E + N L I+++ Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE-IAQKNNALKKIRELEGHISD 1129 Query: 344 -AKELENEE---NQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEED 399 ++L++E N+ E+ + GEE + TEL L AT +L KR E++ Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR--AKR-----EQE 1182 Query: 400 QTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEE 442 TV+ K +EET+ E + + + + E+ T+ +E+ Sbjct: 1183 VTVLK----KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1221 Score = 44.7 bits (104), Expect = 2e-04 Identities = 80/351 (22%), Positives = 141/351 (40%), Gaps = 51/351 (14%) Query: 150 TAVKEKA--GATLRIHGVNSGSSEGAQPNTENGVPEITDAATDQGPAESPPTSPSSASRG 207 T KE A LR+ G E + E V E+ +D +R Sbjct: 1235 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD-----------GERARA 1283 Query: 208 MLSAITNVVQNTGKSVLTGGLDALEFIGKKTMNVLAESDPGFKRTKTLME----RTVSLS 263 L+ + +QN +SV TG L+ E K +A + T+ L++ + +++S Sbjct: 1284 ELNDKVHKLQNEVESV-TGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVS 1342 Query: 264 QMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASL 323 LR+ +E E+ L QL E A + H+ L I ++S+ K+Q F +++ Sbjct: 1343 TKLRQLEE-ERNSLQDQLDEEMEAKQNLE-------RHISTLNIQLSDSKKKLQDFASTV 1394 Query: 324 DGEKLELLKNDLISIKDIFAAKELENEENQEEQG------LEEKGEEFARMLTELLFEL- 376 E LE K KE+EN Q E+ LE+ + L +L+ +L Sbjct: 1395 --EALEEGKKRF--------QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1444 Query: 377 HVAATPDKLNKAMKRAHDWVEEDQTVVSVDV-------AKVSEEETKKEEKEEKSQDPQE 429 + L K ++ + E++ + S A+ E+ETK ++ E Sbjct: 1445 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1504 Query: 430 DKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQ 480 K+E ++T + + M + S + + + +L K ++ L Q EE Q Sbjct: 1505 AKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK-SKRALETQMEEMKTQ 1554 Score = 37.7 bits (86), Expect = 0.028 Identities = 43/197 (21%), Positives = 87/197 (44%), Gaps = 16/197 (8%) Query: 309 SNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARM 368 + E + K ++ L L+ + +L + + + + A EL E + L K +E + Sbjct: 871 TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEI 930 Query: 369 LTELLFELH--------VAATPDKLNKAMKRAHDWVEEDQTV-VSVDVAKVSEEETKKEE 419 L E+ L + A K+ + M + +EE++ + + KV+ E K+ Sbjct: 931 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 990 Query: 420 KEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARC-----IEQLHK--VAELILHG 472 ++E ++ K K+ K +EE +LAE + ++ H+ ++EL + Sbjct: 991 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1050 Query: 473 QEEEKPAQDQAKVLIKL 489 ++EEK Q+ K+ KL Sbjct: 1051 KKEEKSRQELEKLKRKL 1067 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 46.2 bits (108), Expect = 8e-05 Identities = 56/223 (25%), Positives = 103/223 (46%), Gaps = 26/223 (11%) Query: 232 EFIGKKTMNVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGM 291 E I T N+ E + TK + +S++ K++EK R Q+L + G Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR--QELEKLKRKLEGD 1063 Query: 292 LFDEYQGLSHLEA----LEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFA---- 343 D ++ ++ L+A L++ + E ++Q+ LA LD E + N L I+++ Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE-IAQKNNALKKIRELEGHISD 1122 Query: 344 -AKELENEE---NQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEED 399 ++L++E N+ E+ + GEE + TEL L AT +L KR E++ Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR--AKR-----EQE 1175 Query: 400 QTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEE 442 TV+ K +EET+ E + + + + E+ T+ +E+ Sbjct: 1176 VTVLK----KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1214 Score = 44.7 bits (104), Expect = 2e-04 Identities = 80/351 (22%), Positives = 141/351 (40%), Gaps = 51/351 (14%) Query: 150 TAVKEKA--GATLRIHGVNSGSSEGAQPNTENGVPEITDAATDQGPAESPPTSPSSASRG 207 T KE A LR+ G E + E V E+ +D +R Sbjct: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD-----------GERARA 1276 Query: 208 MLSAITNVVQNTGKSVLTGGLDALEFIGKKTMNVLAESDPGFKRTKTLME----RTVSLS 263 L+ + +QN +SV TG L+ E K +A + T+ L++ + +++S Sbjct: 1277 ELNDKVHKLQNEVESV-TGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVS 1335 Query: 264 QMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASL 323 LR+ +E E+ L QL E A + H+ L I ++S+ K+Q F +++ Sbjct: 1336 TKLRQLEE-ERNSLQDQLDEEMEAKQNLE-------RHISTLNIQLSDSKKKLQDFASTV 1387 Query: 324 DGEKLELLKNDLISIKDIFAAKELENEENQEEQG------LEEKGEEFARMLTELLFEL- 376 E LE K KE+EN Q E+ LE+ + L +L+ +L Sbjct: 1388 --EALEEGKKRF--------QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437 Query: 377 HVAATPDKLNKAMKRAHDWVEEDQTVVSVDV-------AKVSEEETKKEEKEEKSQDPQE 429 + L K ++ + E++ + S A+ E+ETK ++ E Sbjct: 1438 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1497 Query: 430 DKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQ 480 K+E ++T + + M + S + + + +L K ++ L Q EE Q Sbjct: 1498 AKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK-SKRALETQMEEMKTQ 1547 Score = 37.7 bits (86), Expect = 0.028 Identities = 43/197 (21%), Positives = 87/197 (44%), Gaps = 16/197 (8%) Query: 309 SNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARM 368 + E + K ++ L L+ + +L + + + + A EL E + L K +E + Sbjct: 864 TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEI 923 Query: 369 LTELLFELH--------VAATPDKLNKAMKRAHDWVEEDQTV-VSVDVAKVSEEETKKEE 419 L E+ L + A K+ + M + +EE++ + + KV+ E K+ Sbjct: 924 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 983 Query: 420 KEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARC-----IEQLHK--VAELILHG 472 ++E ++ K K+ K +EE +LAE + ++ H+ ++EL + Sbjct: 984 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1043 Query: 473 QEEEKPAQDQAKVLIKL 489 ++EEK Q+ K+ KL Sbjct: 1044 KKEEKSRQELEKLKRKL 1060 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 45.8 bits (107), Expect = 1e-04 Identities = 60/292 (20%), Positives = 121/292 (41%), Gaps = 37/292 (12%) Query: 216 VQNTGKSVLTGGLDALEFIGKKTMNVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQ 275 +++ G S + D ++ KK + E + F++ + + + L ++ + K E Sbjct: 116 IEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQ-KRPENS 174 Query: 276 RLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSN--------ESESKVQSFLASLDGEK 327 L + L + G ++ +LE+ N E +++Q L ++ EK Sbjct: 175 LLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEK 234 Query: 328 LELLKNDLISIKDIFAAKELENEENQ-EEQGLEEKGEEFARMLTELLFELHVAATPDKL- 385 E+ N +KD+ ++LE + +Q L+ + + + L + +L ++L Sbjct: 235 SEIQLN----VKDL--KRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELW 288 Query: 386 -------NKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQD------PQEDK- 431 + M R + ++E + + K+ E+E K +EEK + QEDK Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348 Query: 432 -KEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQ 482 ++E+K + EE E + + EQ K+ E QEEE Q++ Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQE-----QEEEMWRQEE 395 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/125 (24%), Positives = 63/125 (50%), Gaps = 4/125 (3%) Query: 345 KELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVS 404 +E+E + +EE+ ++E+ E+ R ++ + +KL K ++ W +E++ Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKI--WEQEEKMWRQ 508 Query: 405 VDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHK 464 + K+ E+E K +E+EEK Q +E +E++ +E M E + + +L + Sbjct: 509 EE--KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQ 566 Query: 465 VAELI 469 AEL+ Sbjct: 567 KAELL 571 Score = 36.2 bits (82), Expect = 0.082 Identities = 35/159 (22%), Positives = 74/159 (46%), Gaps = 12/159 (7%) Query: 326 EKLELLKNDLISIKDIFAAKELENEEN--QEEQGLEEKGEEFARMLTELLFELHVAATPD 383 EK++ + ++ ++ +E + +E ++E+ + E+ E+ E+ + + Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQ------EE 434 Query: 384 KLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEV 443 K+ + + D E+ + V K+ EEE K +E+EEK Q +E +E+++ +E Sbjct: 435 KIRELEEMMQDQEEKLREVEE----KMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490 Query: 444 YMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQ 482 + E + E + Q K+ E QE+E+ Q Q Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529 Score = 35.4 bits (80), Expect = 0.14 Identities = 28/135 (20%), Positives = 60/135 (44%), Gaps = 10/135 (7%) Query: 348 ENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDV 407 E + ++++ + E+ EE R ++ +L + M+ + + E + + + Sbjct: 412 EKKMREQDEKIREQEEEMWRQEEKIR----------ELEEMMQDQEEKLREVEEKMQEEE 461 Query: 408 AKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAE 467 K+ E+E K + +EEK Q+ +E ++K EE E + + EQ K+ E Sbjct: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521 Query: 468 LILHGQEEEKPAQDQ 482 Q +E+ ++Q Sbjct: 522 QEEKMQRQEEKMREQ 536 Score = 33.5 bits (75), Expect = 0.53 Identities = 29/138 (21%), Positives = 56/138 (40%), Gaps = 12/138 (8%) Query: 348 ENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDV 407 E + ++++ ++E+ EE R E + +K + M R + E + Sbjct: 373 EEKIREQDEKIQEQEEEMWRQ------EEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426 Query: 408 AKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAE 467 ++ +E K E EE QD +E+K + +EE E + E + Q K+ E Sbjct: 427 EEMWRQEEKIRELEEMMQD------QEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480 Query: 468 LILHGQEEEKPAQDQAKV 485 +EK + + K+ Sbjct: 481 QEEKTWRQEKLLKQEEKI 498 Score = 33.5 bits (75), Expect = 0.53 Identities = 27/133 (20%), Positives = 59/133 (44%), Gaps = 6/133 (4%) Query: 350 EENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAK 409 E+ +E EEK E M+ + +L ++ + M+ + ++E + + K Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLR------EVEEKMQEEEEKMQEQEEKIQRQEEK 477 Query: 410 VSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELI 469 + E+E K +E+ + ++ ++E+K EE E + E + Q K+ E Sbjct: 478 IQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537 Query: 470 LHGQEEEKPAQDQ 482 + ++E+ Q+Q Sbjct: 538 VRLWQQEEKMQEQ 550 >gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] Length = 1220 Score = 45.4 bits (106), Expect = 1e-04 Identities = 49/194 (25%), Positives = 89/194 (45%), Gaps = 33/194 (17%) Query: 262 LSQMLREAKEK------EKQRLAQQL--TMERTAHYGMLFDEYQGLS-------HL-EAL 305 L Q L+E+++ EKQ L QL + + H L + L HL + L Sbjct: 527 LQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQL 586 Query: 306 EILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEF 365 + + E+ SK+Q ++++ N L +++I ++L+ +++ E + L++K +E Sbjct: 587 DEVEKETRSKLQ---------EIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQE- 636 Query: 366 ARMLTELLFELHVAATPDKLNKAMKRAHDWVEE-DQTVVSVDVAKVSEEETKKEEKEEKS 424 R + EL + A +A +R W+E Q K+ EEE K E+ K Sbjct: 637 -RKIIELEKQKEEAQ-----RRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKK 690 Query: 425 QDPQEDKKEEKKTK 438 +D +E K+E + K Sbjct: 691 KDGEEKGKQEAQDK 704 >gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] Length = 1721 Score = 45.4 bits (106), Expect = 1e-04 Identities = 49/194 (25%), Positives = 89/194 (45%), Gaps = 33/194 (17%) Query: 262 LSQMLREAKEK------EKQRLAQQL--TMERTAHYGMLFDEYQGLS-------HL-EAL 305 L Q L+E+++ EKQ L QL + + H L + L HL + L Sbjct: 527 LQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQL 586 Query: 306 EILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEF 365 + + E+ SK+Q ++++ N L +++I ++L+ +++ E + L++K +E Sbjct: 587 DEVEKETRSKLQ---------EIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQE- 636 Query: 366 ARMLTELLFELHVAATPDKLNKAMKRAHDWVEE-DQTVVSVDVAKVSEEETKKEEKEEKS 424 R + EL + A +A +R W+E Q K+ EEE K E+ K Sbjct: 637 -RKIIELEKQKEEAQ-----RRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKK 690 Query: 425 QDPQEDKKEEKKTK 438 +D +E K+E + K Sbjct: 691 KDGEEKGKQEAQDK 704 >gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] Length = 983 Score = 45.1 bits (105), Expect = 2e-04 Identities = 95/478 (19%), Positives = 176/478 (36%), Gaps = 77/478 (16%) Query: 68 PPVQPQDANALEPPLNRDVTEDTLAECIDSVSLEAEPRSEIPLQEQNYPAVDSPPSGGGW 127 PP+ P + + P R +T L+ E ++EI +N + +G Sbjct: 281 PPISPTQLSDVSSP--RSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGAD- 337 Query: 128 AGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHGVNSGSSEGAQPNTENGVPEITDA 187 SLL +S L ++ + A+L +H A+ E D+ Sbjct: 338 --------SLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDS 389 Query: 188 ----ATDQGPAESPP--TSPSSASRGMLSAITNVVQNTGKSVLTGG--LDALEFIGKKTM 239 TD GP+ P TSP + S+ + ++ + GKS + L+ I + Sbjct: 390 YHSTQTDLGPSLGKPGETSPPDSK----SSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQ 445 Query: 240 NVLAESDPGFKRTKT----------------LMERTVSLSQMLREAKEKEKQRLAQQLTM 283 L S+ K+ + + E + LSQ L+E + K ++ + + L++ Sbjct: 446 KRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSV 505 Query: 284 ERTAHYGMLFDE-YQGLSHLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIF 342 ++ G++ E SH L + E Q +L+ + K Sbjct: 506 QKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEK---------- 555 Query: 343 AAKELENEENQEEQG--LEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQ 400 +ELE + + E+G ++ EE+ M + + + +NK + +E Q Sbjct: 556 -VRELEEKLVEREKGTVIKPPVEEYEEMKSS------YCSVIENMNKEKAFLFEKYQEAQ 608 Query: 401 TVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKE---------EKKTKTIEEVYMSSIESL 451 + + ++T K + +++ D ED KE K+ + ++Y + L Sbjct: 609 EEI------MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL 662 Query: 452 AEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLT 509 + R + L V +H E EK Q K A+ +E+ S K N LT Sbjct: 663 EDYRKR--KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL-SEMKSQYSKVLNELT 717 Score = 43.5 bits (101), Expect = 5e-04 Identities = 56/296 (18%), Positives = 128/296 (43%), Gaps = 34/296 (11%) Query: 255 LMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESES 314 L ++ LSQ+ +EA+ + + ++ + TA EY + E L L+N S + Sbjct: 644 LNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA-------EYIHKAEHEKLMQLTNVSRA 696 Query: 315 KVQSFLASLDGEKLELLKNDLISIKDIF----------------------AAKELENEEN 352 K + L+ + + ++L N+L +K + AAKE+E + + Sbjct: 697 KAEDALSEMKSQYSKVL-NELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKIS 755 Query: 353 QEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAK-VS 411 ++ L K E A++ +LL E + ++ +E + +V++ + + V Sbjct: 756 NLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVK 815 Query: 412 EEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILH 471 E+E E + + + K+E++ +T+ + + L + + E+L AE+ + Sbjct: 816 EKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEEL---AEMKRY 872 Query: 472 GQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSV 527 + K +D+ K + +++ + +L+ S +T S ++++ L + V Sbjct: 873 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQV 928 >gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] Length = 972 Score = 45.1 bits (105), Expect = 2e-04 Identities = 95/478 (19%), Positives = 176/478 (36%), Gaps = 77/478 (16%) Query: 68 PPVQPQDANALEPPLNRDVTEDTLAECIDSVSLEAEPRSEIPLQEQNYPAVDSPPSGGGW 127 PP+ P + + P R +T L+ E ++EI +N + +G Sbjct: 270 PPISPTQLSDVSSP--RSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGAD- 326 Query: 128 AGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHGVNSGSSEGAQPNTENGVPEITDA 187 SLL +S L ++ + A+L +H A+ E D+ Sbjct: 327 --------SLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDS 378 Query: 188 ----ATDQGPAESPP--TSPSSASRGMLSAITNVVQNTGKSVLTGG--LDALEFIGKKTM 239 TD GP+ P TSP + S+ + ++ + GKS + L+ I + Sbjct: 379 YHSTQTDLGPSLGKPGETSPPDSK----SSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQ 434 Query: 240 NVLAESDPGFKRTKT----------------LMERTVSLSQMLREAKEKEKQRLAQQLTM 283 L S+ K+ + + E + LSQ L+E + K ++ + + L++ Sbjct: 435 KRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSV 494 Query: 284 ERTAHYGMLFDE-YQGLSHLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIF 342 ++ G++ E SH L + E Q +L+ + K Sbjct: 495 QKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEK---------- 544 Query: 343 AAKELENEENQEEQG--LEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQ 400 +ELE + + E+G ++ EE+ M + + + +NK + +E Q Sbjct: 545 -VRELEEKLVEREKGTVIKPPVEEYEEMKSS------YCSVIENMNKEKAFLFEKYQEAQ 597 Query: 401 TVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKE---------EKKTKTIEEVYMSSIESL 451 + + ++T K + +++ D ED KE K+ + ++Y + L Sbjct: 598 EEI------MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL 651 Query: 452 AEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLT 509 + R + L V +H E EK Q K A+ +E+ S K N LT Sbjct: 652 EDYRKR--KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL-SEMKSQYSKVLNELT 706 Score = 43.5 bits (101), Expect = 5e-04 Identities = 56/296 (18%), Positives = 128/296 (43%), Gaps = 34/296 (11%) Query: 255 LMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESES 314 L ++ LSQ+ +EA+ + + ++ + TA EY + E L L+N S + Sbjct: 633 LNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA-------EYIHKAEHEKLMQLTNVSRA 685 Query: 315 KVQSFLASLDGEKLELLKNDLISIKDIF----------------------AAKELENEEN 352 K + L+ + + ++L N+L +K + AAKE+E + + Sbjct: 686 KAEDALSEMKSQYSKVL-NELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKIS 744 Query: 353 QEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAK-VS 411 ++ L K E A++ +LL E + ++ +E + +V++ + + V Sbjct: 745 NLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVK 804 Query: 412 EEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILH 471 E+E E + + + K+E++ +T+ + + L + + E+L AE+ + Sbjct: 805 EKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEEL---AEMKRY 861 Query: 472 GQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSV 527 + K +D+ K + +++ + +L+ S +T S ++++ L + V Sbjct: 862 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQV 917 >gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] Length = 980 Score = 45.1 bits (105), Expect = 2e-04 Identities = 95/478 (19%), Positives = 176/478 (36%), Gaps = 77/478 (16%) Query: 68 PPVQPQDANALEPPLNRDVTEDTLAECIDSVSLEAEPRSEIPLQEQNYPAVDSPPSGGGW 127 PP+ P + + P R +T L+ E ++EI +N + +G Sbjct: 278 PPISPTQLSDVSSP--RSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGAD- 334 Query: 128 AGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHGVNSGSSEGAQPNTENGVPEITDA 187 SLL +S L ++ + A+L +H A+ E D+ Sbjct: 335 --------SLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDS 386 Query: 188 ----ATDQGPAESPP--TSPSSASRGMLSAITNVVQNTGKSVLTGG--LDALEFIGKKTM 239 TD GP+ P TSP + S+ + ++ + GKS + L+ I + Sbjct: 387 YHSTQTDLGPSLGKPGETSPPDSK----SSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQ 442 Query: 240 NVLAESDPGFKRTKT----------------LMERTVSLSQMLREAKEKEKQRLAQQLTM 283 L S+ K+ + + E + LSQ L+E + K ++ + + L++ Sbjct: 443 KRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSV 502 Query: 284 ERTAHYGMLFDE-YQGLSHLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIF 342 ++ G++ E SH L + E Q +L+ + K Sbjct: 503 QKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEK---------- 552 Query: 343 AAKELENEENQEEQG--LEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQ 400 +ELE + + E+G ++ EE+ M + + + +NK + +E Q Sbjct: 553 -VRELEEKLVEREKGTVIKPPVEEYEEMKSS------YCSVIENMNKEKAFLFEKYQEAQ 605 Query: 401 TVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKE---------EKKTKTIEEVYMSSIESL 451 + + ++T K + +++ D ED KE K+ + ++Y + L Sbjct: 606 EEI------MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL 659 Query: 452 AEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLT 509 + R + L V +H E EK Q K A+ +E+ S K N LT Sbjct: 660 EDYRKR--KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL-SEMKSQYSKVLNELT 714 Score = 43.5 bits (101), Expect = 5e-04 Identities = 56/296 (18%), Positives = 128/296 (43%), Gaps = 34/296 (11%) Query: 255 LMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESES 314 L ++ LSQ+ +EA+ + + ++ + TA EY + E L L+N S + Sbjct: 641 LNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA-------EYIHKAEHEKLMQLTNVSRA 693 Query: 315 KVQSFLASLDGEKLELLKNDLISIKDIF----------------------AAKELENEEN 352 K + L+ + + ++L N+L +K + AAKE+E + + Sbjct: 694 KAEDALSEMKSQYSKVL-NELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKIS 752 Query: 353 QEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAK-VS 411 ++ L K E A++ +LL E + ++ +E + +V++ + + V Sbjct: 753 NLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVK 812 Query: 412 EEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILH 471 E+E E + + + K+E++ +T+ + + L + + E+L AE+ + Sbjct: 813 EKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEEL---AEMKRY 869 Query: 472 GQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSV 527 + K +D+ K + +++ + +L+ S +T S ++++ L + V Sbjct: 870 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQV 925 >gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] Length = 980 Score = 45.1 bits (105), Expect = 2e-04 Identities = 95/478 (19%), Positives = 176/478 (36%), Gaps = 77/478 (16%) Query: 68 PPVQPQDANALEPPLNRDVTEDTLAECIDSVSLEAEPRSEIPLQEQNYPAVDSPPSGGGW 127 PP+ P + + P R +T L+ E ++EI +N + +G Sbjct: 278 PPISPTQLSDVSSP--RSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGAD- 334 Query: 128 AGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHGVNSGSSEGAQPNTENGVPEITDA 187 SLL +S L ++ + A+L +H A+ E D+ Sbjct: 335 --------SLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDS 386 Query: 188 ----ATDQGPAESPP--TSPSSASRGMLSAITNVVQNTGKSVLTGG--LDALEFIGKKTM 239 TD GP+ P TSP + S+ + ++ + GKS + L+ I + Sbjct: 387 YHSTQTDLGPSLGKPGETSPPDSK----SSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQ 442 Query: 240 NVLAESDPGFKRTKT----------------LMERTVSLSQMLREAKEKEKQRLAQQLTM 283 L S+ K+ + + E + LSQ L+E + K ++ + + L++ Sbjct: 443 KRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSV 502 Query: 284 ERTAHYGMLFDE-YQGLSHLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIF 342 ++ G++ E SH L + E Q +L+ + K Sbjct: 503 QKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEK---------- 552 Query: 343 AAKELENEENQEEQG--LEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQ 400 +ELE + + E+G ++ EE+ M + + + +NK + +E Q Sbjct: 553 -VRELEEKLVEREKGTVIKPPVEEYEEMKSS------YCSVIENMNKEKAFLFEKYQEAQ 605 Query: 401 TVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKE---------EKKTKTIEEVYMSSIESL 451 + + ++T K + +++ D ED KE K+ + ++Y + L Sbjct: 606 EEI------MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL 659 Query: 452 AEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLT 509 + R + L V +H E EK Q K A+ +E+ S K N LT Sbjct: 660 EDYRKR--KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL-SEMKSQYSKVLNELT 714 Score = 43.5 bits (101), Expect = 5e-04 Identities = 56/296 (18%), Positives = 128/296 (43%), Gaps = 34/296 (11%) Query: 255 LMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESES 314 L ++ LSQ+ +EA+ + + ++ + TA EY + E L L+N S + Sbjct: 641 LNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA-------EYIHKAEHEKLMQLTNVSRA 693 Query: 315 KVQSFLASLDGEKLELLKNDLISIKDIF----------------------AAKELENEEN 352 K + L+ + + ++L N+L +K + AAKE+E + + Sbjct: 694 KAEDALSEMKSQYSKVL-NELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKIS 752 Query: 353 QEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAK-VS 411 ++ L K E A++ +LL E + ++ +E + +V++ + + V Sbjct: 753 NLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVK 812 Query: 412 EEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILH 471 E+E E + + + K+E++ +T+ + + L + + E+L AE+ + Sbjct: 813 EKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEEL---AEMKRY 869 Query: 472 GQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSV 527 + K +D+ K + +++ + +L+ S +T S ++++ L + V Sbjct: 870 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQV 925 >gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] Length = 980 Score = 45.1 bits (105), Expect = 2e-04 Identities = 95/478 (19%), Positives = 176/478 (36%), Gaps = 77/478 (16%) Query: 68 PPVQPQDANALEPPLNRDVTEDTLAECIDSVSLEAEPRSEIPLQEQNYPAVDSPPSGGGW 127 PP+ P + + P R +T L+ E ++EI +N + +G Sbjct: 278 PPISPTQLSDVSSP--RSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGAD- 334 Query: 128 AGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHGVNSGSSEGAQPNTENGVPEITDA 187 SLL +S L ++ + A+L +H A+ E D+ Sbjct: 335 --------SLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDS 386 Query: 188 ----ATDQGPAESPP--TSPSSASRGMLSAITNVVQNTGKSVLTGG--LDALEFIGKKTM 239 TD GP+ P TSP + S+ + ++ + GKS + L+ I + Sbjct: 387 YHSTQTDLGPSLGKPGETSPPDSK----SSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQ 442 Query: 240 NVLAESDPGFKRTKT----------------LMERTVSLSQMLREAKEKEKQRLAQQLTM 283 L S+ K+ + + E + LSQ L+E + K ++ + + L++ Sbjct: 443 KRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSV 502 Query: 284 ERTAHYGMLFDE-YQGLSHLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIF 342 ++ G++ E SH L + E Q +L+ + K Sbjct: 503 QKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEK---------- 552 Query: 343 AAKELENEENQEEQG--LEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQ 400 +ELE + + E+G ++ EE+ M + + + +NK + +E Q Sbjct: 553 -VRELEEKLVEREKGTVIKPPVEEYEEMKSS------YCSVIENMNKEKAFLFEKYQEAQ 605 Query: 401 TVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKE---------EKKTKTIEEVYMSSIESL 451 + + ++T K + +++ D ED KE K+ + ++Y + L Sbjct: 606 EEI------MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL 659 Query: 452 AEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLT 509 + R + L V +H E EK Q K A+ +E+ S K N LT Sbjct: 660 EDYRKR--KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL-SEMKSQYSKVLNELT 714 Score = 43.5 bits (101), Expect = 5e-04 Identities = 56/296 (18%), Positives = 128/296 (43%), Gaps = 34/296 (11%) Query: 255 LMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESES 314 L ++ LSQ+ +EA+ + + ++ + TA EY + E L L+N S + Sbjct: 641 LNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA-------EYIHKAEHEKLMQLTNVSRA 693 Query: 315 KVQSFLASLDGEKLELLKNDLISIKDIF----------------------AAKELENEEN 352 K + L+ + + ++L N+L +K + AAKE+E + + Sbjct: 694 KAEDALSEMKSQYSKVL-NELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKIS 752 Query: 353 QEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAK-VS 411 ++ L K E A++ +LL E + ++ +E + +V++ + + V Sbjct: 753 NLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVK 812 Query: 412 EEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILH 471 E+E E + + + K+E++ +T+ + + L + + E+L AE+ + Sbjct: 813 EKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEEL---AEMKRY 869 Query: 472 GQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSV 527 + K +D+ K + +++ + +L+ S +T S ++++ L + V Sbjct: 870 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQV 925 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 45.1 bits (105), Expect = 2e-04 Identities = 72/332 (21%), Positives = 141/332 (42%), Gaps = 57/332 (17%) Query: 253 KTLMERTVSLSQMLR----EAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEIL 308 K L+++ L + L E +KEKQ A+ L M + G+ +A+ L Sbjct: 972 KKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGIS----------DAVSRL 1021 Query: 309 SNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARM 368 + +++S + + EL ND+ISI + ++ E + E L+EK +E A + Sbjct: 1022 ETNQKEQIESLT---EVHRREL--NDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAEL 1076 Query: 369 LTELLFELHVAATPDKLNKAMK-RAHDWVEEDQTV---------VSVDVAKVSEEETKKE 418 ++L +++NK + + V++D T+ S V ++++ETK + Sbjct: 1077 KQKILL---FGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLK 1133 Query: 419 EKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQL--------HKVAELIL 470 EK + D + K T + + ++ LAE R + +L + L Sbjct: 1134 AHLEKL---EVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKS 1190 Query: 471 HGQEEEKPAQDQAKVLIKLTTAM-------CNEVASLSKKFTNSLTTVGSNKKAEVLNPM 523 ++ K +D++ KL+ + C + +L + TN L + S+K +L Sbjct: 1191 SHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAIL--- 1247 Query: 524 ISSVLLEGCNSTTYIQDAFQLLLPVLQVSHIQ 555 S + + TT +++A LL+ VS ++ Sbjct: 1248 --SRISHCQHRTTKVKEA--LLIKTCTVSELE 1275 Score = 43.1 bits (100), Expect = 7e-04 Identities = 62/278 (22%), Positives = 115/278 (41%), Gaps = 27/278 (9%) Query: 243 AESDPGFKRT-KTLMERTVSLSQMLREAKEKE----KQRLAQQLTMERTAHYGMLFDEYQ 297 AE D K KT E +SL Q L K++ K+ +Q+ + H L + Q Sbjct: 435 AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQ 494 Query: 298 GLSHLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELE-------NE 350 L+ + L+ E + +++ L E L++ + ++ A +ELE E Sbjct: 495 ELT--KKLQTREREFQEQMKVALEKSQSEYLKISQEK--EQQESLALEELELQKKAILTE 550 Query: 351 ENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKV 410 + + L+++ E + + EL L + +K H E+++ + V Sbjct: 551 SENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVM-- 608 Query: 411 SEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELIL 470 +K + E +S Q+D +K + +++ Y + +E L E + E L K E+I Sbjct: 609 ----VEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIF 664 Query: 471 HGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSL 508 EE + K+ +K T E+ SLS + + L Sbjct: 665 QAHIEEMNEKTLEKLDVKQT-----ELESLSSELSEVL 697 Score = 37.4 bits (85), Expect = 0.037 Identities = 63/290 (21%), Positives = 119/290 (41%), Gaps = 43/290 (14%) Query: 214 NVVQNTGKSVLTGGLDALEFIGKKTMNVLAESDPGFKRTKTLMERTVS--LSQMLREAKE 271 ++++ KSV + + L + + NV A ++ ++ +++T +S + R E Sbjct: 1689 HILEEKLKSVESSQSETL-IVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTE 1747 Query: 272 KEK--QRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASLDGEKLE 329 KEK QR+ Q+ ++H+ M + L LE E +E +S + L+ + Sbjct: 1748 KEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKN-- 1805 Query: 330 LLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAM 389 K LI + + KE Q +Q LE ++ + L E + L + + Sbjct: 1806 -KKYSLIVAQHV--EKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQI------LEQKI 1856 Query: 390 KRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDP----------QEDKKEEKKTKT 439 K + + V V++ EE T K EK + Q +E+ +E+ K+ Sbjct: 1857 KELDSCLVRQKEVHRVEM----EELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHL 1912 Query: 440 IEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKL 489 ++ +S++E+ H E L G E EK Q K +++L Sbjct: 1913 VQPKLLSNMEA-----------QHNDLEFKLAGAEREK--QKLGKEIVRL 1949 Score = 35.4 bits (80), Expect = 0.14 Identities = 51/222 (22%), Positives = 99/222 (44%), Gaps = 38/222 (17%) Query: 230 ALEFIGKKTMNVLAESDPGFK---------RTKTLMERTVSLSQMLREAKEKEKQRLAQQ 280 ALE + + +L ES+ + RT+ ++E SL + L+E K + K LA Sbjct: 536 ALEELELQKKAILTESENKLRDLQQEAETYRTR-ILELESSLEKSLQENKNQSKD-LAVH 593 Query: 281 LTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKD 340 L E+ H + + H LE L ++ ++ L EKL++LK + + Sbjct: 594 LEAEKNKHNKEITVMVE--KHKTELESLKHQQDA--------LWTEKLQVLKQQYQTEME 643 Query: 341 IFAAKELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQ 400 K E E ++E L++K E++F+ H+ +++N+ D + + Sbjct: 644 ----KLREKCEQEKETLLKDK---------EIIFQAHI----EEMNEKTLEKLDVKQTEL 686 Query: 401 TVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEE 442 +S ++++V + K EE+ +D + K+E + K E+ Sbjct: 687 ESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQ 728 Score = 34.3 bits (77), Expect = 0.31 Identities = 53/226 (23%), Positives = 101/226 (44%), Gaps = 23/226 (10%) Query: 254 TLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESE 313 T+ E + L +EA EK++Q L E FD +G +E + + E Sbjct: 1459 TVKELQIQLELKSKEAYEKDEQI---NLLKEELDQQNKRFDCLKG--EMEDDKSKMEKKE 1513 Query: 314 SKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELL 373 S +++ L S +EL + +I + E+ NQ++ +E K EL+ Sbjct: 1514 SNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKD-IEHK---------ELV 1563 Query: 374 FEL-HVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKK 432 +L H ++ + +K A E+ T+ + + +E ETKK+E E + K Sbjct: 1564 QKLQHFQELGEEKDNRVKEAE---EKILTLENQVYSMKAELETKKKELEHVNLSV---KS 1617 Query: 433 EEKKTKTIEEVYMS-SIESLAEVTARCIEQLHKVAELILHGQEEEK 477 +E++ K +E+ S S LAE+ + +++ + + +L EE++ Sbjct: 1618 KEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKE 1663 Score = 30.4 bits (67), Expect = 4.5 Identities = 46/280 (16%), Positives = 121/280 (43%), Gaps = 26/280 (9%) Query: 231 LEFIGKKTMNVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYG 290 LE + + VL + L ++T + Q L +++K QQ+ H Sbjct: 686 LESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEV 745 Query: 291 MLFDEYQGLS-HLEALEILSNESESKVQSFLASLDGEKLELLKND----LISIK-DIFAA 344 + + L + LE+L E + ++ A ++ + ++ +++ S K D+F Sbjct: 746 SIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVF-- 803 Query: 345 KELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVS 404 + ++ +++ + EE+ + + L +L E ++ + A ++ Sbjct: 804 QSYQSATHEQTKAYEEQLAQLQQKLLDLETE--------RILLTKQVAEVEAQKKDVCTE 855 Query: 405 VDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHK 464 +D K+ ++ ++ +++ S+ E+K K++ +VY S +E + + + L + Sbjct: 856 LDAHKIQVQDLMQQLEKQNSE-------MEQKVKSLTQVYESKLEDGNKEQEQTKQILVE 908 Query: 465 VAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKF 504 +IL +E +K + ++L + +A + + L++++ Sbjct: 909 KENMILQMREGQK---KEIEILTQKLSAKEDSIHILNEEY 945 Score = 29.6 bits (65), Expect = 7.7 Identities = 64/352 (18%), Positives = 137/352 (38%), Gaps = 63/352 (17%) Query: 240 NVLAESDPGFKRT-KTLMERTVSLSQMLREAKE--KEKQRLAQQLTMERTAHYGML---- 292 +++ E + +RT K L ++ L +L+E + KE Q + L + G L Sbjct: 738 SIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQAS 797 Query: 293 -----FDEYQGLSHLEALEILSNESESKVQSFLASLDGEKL---------ELLKNDL--- 335 F YQ +H + E +++Q L L+ E++ E K D+ Sbjct: 798 AKLDVFQSYQSATHEQTKAY--EEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTE 855 Query: 336 -----ISIKDIFAAKELENEENQEE--------QGLEEKGEEFARMLTELLFELHVAATP 382 I ++D+ E +N E +++ + E G + ++L E Sbjct: 856 LDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMIL- 914 Query: 383 DKLNKAMKRAHDWVEEDQTVVSVDVAKVSEE-ETKKEEKEEKSQDPQEDKKEEKKT---- 437 ++ + K+ + + + + + ++EE ETK + +E+K + ++ KE ++T Sbjct: 915 -QMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKK 973 Query: 438 ---------KTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEE-EKPAQDQAKVLI 487 K +E + + + A+ +E + I E ++Q + L Sbjct: 974 LLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLT 1033 Query: 488 KLTTAMCNEVASLSKKFTN-------SLTTVGSNKKAEVLNPMISSVLLEGC 532 ++ N+V S+ +K N + + +K + + + +LL GC Sbjct: 1034 EVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGC 1085 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 44.7 bits (104), Expect = 2e-04 Identities = 53/234 (22%), Positives = 102/234 (43%), Gaps = 27/234 (11%) Query: 270 KEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASLDGEKLE 329 ++K+ R ++LT ER A + + Y+ E L+ E +K+Q L ++ EK E Sbjct: 187 QKKKADRYIEELTKERDA---LSLELYRNTITDEELK----EKNAKLQEKLQLVESEKSE 239 Query: 330 LLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKA- 388 + N + +K +L + Q + + G+E + +L ++ ++LN+ Sbjct: 240 IQLN-VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298 Query: 389 ---MKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQE---DKKE--------- 433 M R + ++E + + K+ E+E K E+EEK + +E +K+E Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358 Query: 434 ---EKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAK 484 E+K + EE+ E + E+ K+ EL E+EK + + K Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412 Score = 40.4 bits (93), Expect = 0.004 Identities = 35/143 (24%), Positives = 62/143 (43%), Gaps = 17/143 (11%) Query: 348 ENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDV 407 + E+ QE++ K EE R E + E + ++ + + E + + Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQE---------EKIREQEEKIREQEEMTQEQE 646 Query: 408 AKVSEEETKKEEKEEKSQDPQED--------KKEEKKTKTIEEVYMSSIESLAEVTARCI 459 K+ E+E K E+EEK Q+ +E +++EKK + EE E + E + Sbjct: 647 EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 706 Query: 460 EQLHKVAELILHGQEEEKPAQDQ 482 EQ K+ E QE+E+ + Q Sbjct: 707 EQEEKMCEQEEKMQEQEEKMRRQ 729 Score = 38.1 bits (87), Expect = 0.022 Identities = 51/248 (20%), Positives = 105/248 (42%), Gaps = 21/248 (8%) Query: 257 ERTVSLSQMLREAKEK-----EKQRLAQQLTMERTAHYG----MLFDEYQGLSHLEALEI 307 E+ + +RE +EK EK R +++ E+ M++++ + + E + + Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM-M 372 Query: 308 LSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKEL--------ENEENQEEQGLE 359 E + + Q + EK+ L+ + + I +E E E+ QE++ Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432 Query: 360 EKGEEFARMLTELLFELH--VAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKK 417 + EE R E + E + +K+++ K + ++Q + K+ E+E Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW 492 Query: 418 EEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEK 477 +KE+ + ++ +K+E+K EE E + E + Q K+ E +EEEK Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552 Query: 478 PAQDQAKV 485 +Q K+ Sbjct: 553 -MHEQEKI 559 Score = 37.4 bits (85), Expect = 0.037 Identities = 30/156 (19%), Positives = 75/156 (48%), Gaps = 5/156 (3%) Query: 348 ENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDV 407 E + ++E+ + E+ E+ R ++ + + +K+++ K W EE + + Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI---WEEEKRQEQEDKM 572 Query: 408 AKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAE 467 + +EE +E++E+ + ++ +++E+K + EE E + E + EQ K+ E Sbjct: 573 WR--QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630 Query: 468 LILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKK 503 +E+E+ Q+Q + + + MC + + ++ Sbjct: 631 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666 Score = 36.2 bits (82), Expect = 0.082 Identities = 31/162 (19%), Positives = 69/162 (42%), Gaps = 6/162 (3%) Query: 348 ENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDW-----VEEDQTV 402 E E+ QE++ + EE R E ++ + + + W + E + Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620 Query: 403 VSVDVAKVSEEETK-KEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQ 461 + K+ E+E K +E++E + ++ ++E+K EE E++ + EQ Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQ 680 Query: 462 LHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKK 503 K+ E +E+E+ Q+Q + + + MC + + ++ Sbjct: 681 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 722 Score = 33.1 bits (74), Expect = 0.70 Identities = 25/139 (17%), Positives = 64/139 (46%), Gaps = 10/139 (7%) Query: 311 ESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLT 370 E E K+Q + ++ ++ + + ++ + E E + ++E+ ++E+ E R Sbjct: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE 675 Query: 371 ELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQED 430 ++ + K ++ + + E + ++ K+ E+E K E+EEK Q+ +E Sbjct: 676 KIREQ----------EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725 Query: 431 KKEEKKTKTIEEVYMSSIE 449 + +++ +EV + E Sbjct: 726 MRRQEEKMWEQEVRLRQQE 744 Score = 30.4 bits (67), Expect = 4.5 Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 9/121 (7%) Query: 348 ENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDV 407 E EE +EQ E+ GE+ +M + + + M R + + E + + Sbjct: 637 EQEEMTQEQE-EKMGEQEEKMCEQ-------EEKMQEQEETMWRQEEKIREQEKKIREQE 688 Query: 408 AKVSE-EETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVA 466 K+ E EE +E++E+ + ++ ++E+K + EE E + E R +Q K+ Sbjct: 689 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748 Query: 467 E 467 E Sbjct: 749 E 749 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 44.3 bits (103), Expect = 3e-04 Identities = 58/251 (23%), Positives = 109/251 (43%), Gaps = 30/251 (11%) Query: 259 TVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQS 318 T + Q LR +E+E L + L E H + D Q H ALE LS + E + + Sbjct: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ--RHATALEELSEQLE-QAKR 1217 Query: 319 FLASLDGEK--LELLKNDLISIKDIFAAKELENEENQEE-----QGLEEKGEEFARMLTE 371 F A+L+ K LE +L + + E+E +++ Q L K E R+ E Sbjct: 1218 FKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVE 1277 Query: 372 LL-----FELHVAATPDKLNKAMKRAHDWVEEDQTVVSV--DVAKVSEEETK-------- 416 L + + L +A K+ + ++ ++ S D ++ +EET+ Sbjct: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR 1337 Query: 417 -KEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEE 475 ++ +EEK+ ++ ++EE+ K +E+ ++ LA+ + + L + L +E Sbjct: 1338 IRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESL----EEA 1393 Query: 476 EKPAQDQAKVL 486 +K A+ L Sbjct: 1394 KKKLLKDAEAL 1404 Score = 35.8 bits (81), Expect = 0.11 Identities = 61/252 (24%), Positives = 109/252 (43%), Gaps = 37/252 (14%) Query: 258 RTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQ 317 + V + R+A K++Q+L+ ++R Y L H + + + KV+ Sbjct: 794 QAVCRGYLARKAFAKKQQQLSALKVLQRNCA------AYLKLRHWQWWRVFT-----KVK 842 Query: 318 SFL-ASLDGEKLELLKNDLISIKD--IFAAKELENEENQEEQGLEEKGEEFARMLTELLF 374 L + E+L+ +L+ +K+ ELE E + +Q LEEK + +L Sbjct: 843 PLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNI----LAEQLQA 898 Query: 375 ELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKE- 433 E + A +++ + +EE + + E++ EE+EE++Q Q +KK+ Sbjct: 899 ETELFAEAEEMRARLAAKKQELEEI----------LHDLESRVEEEEERNQILQNEKKKM 948 Query: 434 EKKTKTIEEVYMSSIESLAEVTARCIEQLHKV-AELILHGQEEE-KPAQDQAKVLIKLTT 491 + + +EE + E AR QL KV AE + EEE +DQ IK Sbjct: 949 QAHIQDLEE------QLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK 1002 Query: 492 AMCNEVASLSKK 503 M + +A S + Sbjct: 1003 LMEDRIAECSSQ 1014 Score = 30.4 bits (67), Expect = 4.5 Identities = 65/297 (21%), Positives = 123/297 (41%), Gaps = 51/297 (17%) Query: 250 KRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGL-----SHLEA 304 K +T +E + + + +EK LA+QL E LF E + + + + Sbjct: 865 KEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETE-----LFAEAEEMRARLAAKKQE 919 Query: 305 LEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGE- 363 LE + ++ ES+V+ + E+ ++L+N+ K + A + E+ EE+G +K + Sbjct: 920 LEEILHDLESRVEE-----EEERNQILQNEK---KKMQAHIQDLEEQLDEEEGARQKLQL 971 Query: 364 -------EFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETK 416 + +M E+L + K K K D + E + ++ + K Sbjct: 972 EKVTAEAKIKKMEEEILL---LEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKI 1028 Query: 417 KEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSI--------ESLAEVTARCIE---QLHKV 465 + ++E D +E K+E+KT+ E + + +AE+ A+ E QL K Sbjct: 1029 RNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKK 1088 Query: 466 AE----LILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAE 518 E + G +E + KV+ +L ++A L + F + S KAE Sbjct: 1089 EEELQGALARGDDETLHKNNALKVVRELQA----QIAELQEDFESE---KASRNKAE 1138 >gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] Length = 951 Score = 44.3 bits (103), Expect = 3e-04 Identities = 102/501 (20%), Positives = 186/501 (37%), Gaps = 89/501 (17%) Query: 54 ENAAVQGAGAAAIGPPVQPQDANALEPPLNRDVTEDTLAECIDSVSLE-------AEP-- 104 ENA +Q + I QDA+ P + +++ + I S L AEP Sbjct: 229 ENAGIQSLLLSKIS-----QDADLKTPTKPKQLSDVSSPRSITSTPLSGKESVFFAEPPF 283 Query: 105 RSEIPLQEQNYPAVDSPPSGGGWAGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHG 164 ++EI +N + +G SLL +S L ++ + A+L +H Sbjct: 284 KAEISSIRENKDRLSDSTTGAD---------SLLDISSEADQQDLLSLLQAKVASLTLHN 334 Query: 165 VNSGSSEGAQPNTENGVPEITDA----ATDQGPAESPP--TSPSSASRGMLSAITNVVQN 218 A+ E D+ TD GP+ P TSP + S+ + ++ + Sbjct: 335 KELQDKLQAKSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSPPDSK----SSPSVLIHS 390 Query: 219 TGKSVLTGG--LDALEFIGKKTMNVLAESDPGFKRTKT----------------LMERTV 260 GKS + L+ I + L S+ K+ + + E + Sbjct: 391 LGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS 450 Query: 261 SLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDE-YQGLSHLEALEILSNESESKVQSF 319 LSQ L+E + K ++ + + L++++ G++ E SH L + E Q Sbjct: 451 DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDL 510 Query: 320 LASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQG--LEEKGEEFARMLTELLFELH 377 +L+ + K +ELE + + E+G ++ EE+ M + Sbjct: 511 QNALEESERNKEK-----------VRELEEKLVEREKGTVIKPPVEEYEEMKSS------ 553 Query: 378 VAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKE---- 433 + + +NK + +E Q + + ++T K + +++ D ED KE Sbjct: 554 YCSVIENMNKEKAFLFEKYQEAQEEI------MKLKDTLKSQMTQEASDEAEDMKEAMNR 607 Query: 434 -----EKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIK 488 K+ + ++Y + L + R + L V +H E EK Q K Sbjct: 608 MIDELNKQVSELSQLYKEAQAELEDYRKR--KSLEDVTAEYIHKAEHEKLMQLTNVSRAK 665 Query: 489 LTTAMCNEVASLSKKFTNSLT 509 A+ +E+ S K N LT Sbjct: 666 AEDAL-SEMKSQYSKVLNELT 685 Score = 43.5 bits (101), Expect = 5e-04 Identities = 56/296 (18%), Positives = 128/296 (43%), Gaps = 34/296 (11%) Query: 255 LMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESES 314 L ++ LSQ+ +EA+ + + ++ + TA EY + E L L+N S + Sbjct: 612 LNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA-------EYIHKAEHEKLMQLTNVSRA 664 Query: 315 KVQSFLASLDGEKLELLKNDLISIKDIF----------------------AAKELENEEN 352 K + L+ + + ++L N+L +K + AAKE+E + + Sbjct: 665 KAEDALSEMKSQYSKVL-NELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKIS 723 Query: 353 QEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAK-VS 411 ++ L K E A++ +LL E + ++ +E + +V++ + + V Sbjct: 724 NLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVK 783 Query: 412 EEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILH 471 E+E E + + + K+E++ +T+ + + L + + E+L AE+ + Sbjct: 784 EKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEEL---AEMKRY 840 Query: 472 GQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSV 527 + K +D+ K + +++ + +L+ S +T S ++++ L + V Sbjct: 841 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQV 896 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 43.9 bits (102), Expect = 4e-04 Identities = 47/190 (24%), Positives = 92/190 (48%), Gaps = 21/190 (11%) Query: 326 EKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELLFELH-VAATPDK 384 EKL L +K+I A K E Q EQ L+ + +E A+ L EL +++ ++ ++ Sbjct: 1677 EKLAKKGGKLAEVKNILAQKV--EELPQREQNLDWQEKELAQELEELEWDMEELSWKEEE 1734 Query: 385 LNKA---MKRAHDWVEEDQTVVSVDVAKVSEEETKK--------EEKEEKSQDPQEDKKE 433 LN+ + + E++ ++ K+SEEETK +EKE+ +Q ++ +E Sbjct: 1735 LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEE 1794 Query: 434 EKKTKTIEEVYMSSIESLAEVTARCIEQLHKVA--ELILH-----GQEEEKPAQDQAKVL 486 E++ E + LA+ R I + ++ ++IL+ QE++ AQ++ K+ Sbjct: 1795 EERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLA 1854 Query: 487 IKLTTAMCNE 496 + + N+ Sbjct: 1855 QRKENLLYNK 1864 Score = 43.1 bits (100), Expect = 7e-04 Identities = 52/233 (22%), Positives = 105/233 (45%), Gaps = 10/233 (4%) Query: 250 KRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILS 309 KR + ER +S+ Q + KE + +LT + L + + L++ I Sbjct: 2101 KRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKK----LARKQRKLANKMRRMINK 2156 Query: 310 NESESKVQSFLASLDGEK-LELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARM 368 E ++ +S LA E L+ + I +++ + + +E + ++ E+F+ Sbjct: 2157 EEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQ 2216 Query: 369 LTELLFELHVA----ATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKS 424 + E+ E H + + D+L K + + EE + + +V EEE +++E EE+ Sbjct: 2217 VDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKE-EEEG 2275 Query: 425 QDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEK 477 ++ Q +K+EE+K K +E ++ EV E + + L +EEE+ Sbjct: 2276 EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEE 2328 Score = 41.6 bits (96), Expect = 0.002 Identities = 53/247 (21%), Positives = 105/247 (42%), Gaps = 35/247 (14%) Query: 250 KRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQG-LSHLEALEIL 308 K K L + L+ +R KE++ ++ + R +L DE +G + E + L Sbjct: 2134 KDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFL 2193 Query: 309 ---------SNESESKVQSFLASLDG-EKLELLKNDLISIKDIFAAKE-LENEENQEEQG 357 + + + F + +D E E ++ S+ D +E L +EE +E + Sbjct: 2194 KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREE 2253 Query: 358 LEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKK 417 EE+ EE R E E EE+ V+ + +++ KK Sbjct: 2254 EEEREEEEVREEEEERKE---------------------EEEGEEKQVEKEEEEKKKKKK 2292 Query: 418 EEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEK 477 E+K+E+ Q+ +E +E+++ + EE S E E + E++ + E++ +E++ Sbjct: 2293 EKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEIL--KKEKQF 2350 Query: 478 PAQDQAK 484 Q+Q + Sbjct: 2351 KLQEQRR 2357 Score = 35.4 bits (80), Expect = 0.14 Identities = 53/232 (22%), Positives = 96/232 (41%), Gaps = 39/232 (16%) Query: 303 EALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQE---EQGLE 359 +A E LS E E + L E+ + + +++S K +KE + ++ +E E+ + Sbjct: 1498 QAGEKLSPEEEMLQED--KKLKWEEWKQVWENMLSSK----SKEQQYKDEEEVTLEEEVS 1551 Query: 360 EKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEE 419 +GEE + +TE + ++ H W + + + EE +E Sbjct: 1552 REGEEKEQQVTEE-------------QRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE 1598 Query: 420 KEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHG----QEE 475 +E+ +Q+ ++ +EE+K + + Y+ + E+ + K L G QE Sbjct: 1599 EEKLAQEERQLAQEERK---LAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEA 1655 Query: 476 EKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSV 527 EK AQ + K L K + E L+KK K AEV N + V Sbjct: 1656 EKLAQKRKK-LAKKWEKVAREEEKLAKK---------GGKLAEVKNILAQKV 1697 Score = 32.0 bits (71), Expect = 1.6 Identities = 25/122 (20%), Positives = 58/122 (47%), Gaps = 21/122 (17%) Query: 377 HVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAK-----------VSEEETKKEEKEEKSQ 425 H P + +A K+A D + ++T V + K + +E +KKEEK+ + Sbjct: 1339 HKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQK 1398 Query: 426 DPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAKV 485 P++ +K +K + + ++ + +++ E++ ++A L EEK + + K+ Sbjct: 1399 SPKQGRKAVQKERKVGKIKREMTKEERDMS----EEVEEMATL------EEKVVKQEGKL 1448 Query: 486 LI 487 ++ Sbjct: 1449 VM 1450 Score = 32.0 bits (71), Expect = 1.6 Identities = 34/142 (23%), Positives = 65/142 (45%), Gaps = 16/142 (11%) Query: 345 KELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVS 404 +E E QEE+ L + GE+ + E+L E +K +K W E Q + Sbjct: 1483 EEWEKRLLQEEEKLHQAGEKLSPE-EEMLQE----------DKKLK----WEEWKQVWEN 1527 Query: 405 VDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEV-TARCIEQLH 463 + +K E++ K EE+ ++ + +E+++ T E+ ++ A + R + Sbjct: 1528 MLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKK 1587 Query: 464 KVAELILHGQEEEKPAQDQAKV 485 + E QEEEK AQ++ ++ Sbjct: 1588 RAQEERKLAQEEEKLAQEERQL 1609 Score = 30.4 bits (67), Expect = 4.5 Identities = 31/135 (22%), Positives = 61/135 (45%), Gaps = 14/135 (10%) Query: 348 ENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDV 407 E + QEE+ L ++ E+ A+ E +A KL +A + ++D+ + + Sbjct: 1585 EKKRAQEERKLAQEEEKLAQE------ERQLAQEERKLAQAYVKI---TQDDREMAQAEG 1635 Query: 408 AKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAE 467 +EET + E+ SQ+ ++ ++ KK E E LA+ + E + +A+ Sbjct: 1636 KFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQ 1695 Query: 468 LILHGQEEEKPAQDQ 482 + EE P ++Q Sbjct: 1696 KV-----EELPQREQ 1705 >gi|224458301 family with sequence similarity 186, member A [Homo sapiens] Length = 2351 Score = 43.5 bits (101), Expect = 5e-04 Identities = 79/398 (19%), Positives = 172/398 (43%), Gaps = 38/398 (9%) Query: 79 EPPLNRDVTEDTLAECIDSVSLEAEPRSEIPLQEQNYPAVDSPPSGGGWAGWGSWGKSLL 138 E P ++ T + + SL+ E + EI + + + G K + Sbjct: 553 ESPFDKRPTAAEIKVEPTTESLDKEGKGEIRSLVEPLSMIQFDDTAEPQKGKIKGKKHHI 612 Query: 139 SSASATVGHGLTAVKEKAGATLRIHGVNSGSSEGAQPNTENG-VPEITDAATDQGPAESP 197 SS + T T KE+ ++ H + S A+ +E+ V E D ++Q E Sbjct: 613 SSGTITSKEEKTEEKEELTKQVKSHQLVKSLSRVAKETSESTRVLESPDGKSEQSNLEE- 671 Query: 198 PTSPSSASRGMLSAITNVVQNTGKSVLTGGLDALEFIGKKTMNVLAESDP----GFKRTK 253 +++ + + N GK+ + E + K+ AE++ K + Sbjct: 672 ------FQEAIMAFLKQKIDNIGKAFDKKTVPKEEELLKR-----AEAEKLGIIKAKMEE 720 Query: 254 TLMERTVSLSQMLREAKE--KEKQRLAQQLTMERTAHY--GMLFDEYQGLSHLEALEILS 309 + +++++LR+ K+ KE+Q + + ++ + G+ F + + E+ +LS Sbjct: 721 YFQKVAETVTKILRKYKDTKKEEQVGEKPIKQKKVVSFMPGLHFQKSPISAKSESSTLLS 780 Query: 310 NESESKV-----QSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEE 364 ES V Q LA ++ E+ D+ ++ + E E+ ++EQ L+E E+ Sbjct: 781 YESTDPVINNLIQMILAEIESER------DIPTVSTV-QKDHKEKEKQRQEQYLQEGQEQ 833 Query: 365 FARMLT--ELLFELHVAATP-DKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEET--KKEE 419 + M +LL E ++ +K+++ + W++ + K +EE K+E+ Sbjct: 834 MSGMSLKQQLLGERNLLKEHYEKISENWEEKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQ 893 Query: 420 KEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTAR 457 K+ + ++++K++++ + EE+ SS++ L E T + Sbjct: 894 KQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQK 931 >gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] Length = 2003 Score = 43.1 bits (100), Expect = 7e-04 Identities = 49/251 (19%), Positives = 112/251 (44%), Gaps = 8/251 (3%) Query: 258 RTVSLSQMLREAKE--KEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESK 315 R +SL++ L E +E +E +R + L E A D + + LE ++ ++ + Sbjct: 1509 RALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAND 1568 Query: 316 VQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELLFE 375 +++ + L+ E L + ++ + L+ + ++ QG +E GEE R L + L + Sbjct: 1569 LRAQVTELEDE---LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRD 1625 Query: 376 LHVAATPDKLNKAMK-RAHDWVEEDQTVVSVDVAKVSE--EETKKEEKEEKSQDPQEDKK 432 V ++ + + A +E + + +A + EE K+ ++ ++Q + ++ Sbjct: 1626 AEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWRE 1685 Query: 433 EEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTA 492 E+ + EE++ + ES + E L EL + + QD+ ++ ++ Sbjct: 1686 VEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 1745 Query: 493 MCNEVASLSKK 503 ++ A L +K Sbjct: 1746 NLSKAAILEEK 1756 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 43.1 bits (100), Expect = 7e-04 Identities = 49/251 (19%), Positives = 112/251 (44%), Gaps = 8/251 (3%) Query: 258 RTVSLSQMLREAKE--KEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESK 315 R +SL++ L E +E +E +R + L E A D + + LE ++ ++ + Sbjct: 1501 RALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAND 1560 Query: 316 VQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELLFE 375 +++ + L+ E L + ++ + L+ + ++ QG +E GEE R L + L + Sbjct: 1561 LRAQVTELEDE---LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRD 1617 Query: 376 LHVAATPDKLNKAMK-RAHDWVEEDQTVVSVDVAKVSE--EETKKEEKEEKSQDPQEDKK 432 V ++ + + A +E + + +A + EE K+ ++ ++Q + ++ Sbjct: 1618 AEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWRE 1677 Query: 433 EEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTA 492 E+ + EE++ + ES + E L EL + + QD+ ++ ++ Sbjct: 1678 VEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 1737 Query: 493 MCNEVASLSKK 503 ++ A L +K Sbjct: 1738 NLSKAAILEEK 1748 >gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] Length = 2036 Score = 43.1 bits (100), Expect = 7e-04 Identities = 49/251 (19%), Positives = 112/251 (44%), Gaps = 8/251 (3%) Query: 258 RTVSLSQMLREAKE--KEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESK 315 R +SL++ L E +E +E +R + L E A D + + LE ++ ++ + Sbjct: 1542 RALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAND 1601 Query: 316 VQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELLFE 375 +++ + L+ E L + ++ + L+ + ++ QG +E GEE R L + L + Sbjct: 1602 LRAQVTELEDE---LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRD 1658 Query: 376 LHVAATPDKLNKAMK-RAHDWVEEDQTVVSVDVAKVSE--EETKKEEKEEKSQDPQEDKK 432 V ++ + + A +E + + +A + EE K+ ++ ++Q + ++ Sbjct: 1659 AEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWRE 1718 Query: 433 EEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTA 492 E+ + EE++ + ES + E L EL + + QD+ ++ ++ Sbjct: 1719 VEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 1778 Query: 493 MCNEVASLSKK 503 ++ A L +K Sbjct: 1779 NLSKAAILEEK 1789 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.306 0.124 0.337 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,500,905 Number of Sequences: 37866 Number of extensions: 1042291 Number of successful extensions: 15397 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 189 Number of HSP's successfully gapped in prelim test: 616 Number of HSP's that attempted gapping in prelim test: 9614 Number of HSP's gapped (non-prelim): 3659 length of query: 563 length of database: 18,247,518 effective HSP length: 107 effective length of query: 456 effective length of database: 14,195,856 effective search space: 6473310336 effective search space used: 6473310336 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.