Guide to the Human Genome
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Search of human proteins with 29570782

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29570782 additional sex combs like 1 [Homo sapiens]
         (1541 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29570782 additional sex combs like 1 [Homo sapiens]               3101   0.0  
gi|153792780 additional sex combs like 2 [Homo sapiens]               381   e-105
gi|149944526 additional sex combs like 3 [Homo sapiens]               335   2e-91
gi|9966841 cell death regulator aven [Homo sapiens]                    52   6e-06
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa...    49   5e-05
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    48   8e-05
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    48   8e-05
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]     47   1e-04
gi|21396480 RNA binding protein (autoantigenic, hnRNP-associated...    47   1e-04
gi|13994190 frizzled 8 [Homo sapiens]                                  47   2e-04
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]    47   2e-04
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                       45   4e-04
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]               45   5e-04
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]               45   5e-04
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]               45   5e-04
gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precurs...    45   5e-04
gi|33620755 YEATS domain containing 2 [Homo sapiens]                   45   5e-04
gi|238859557 regulatory factor X1 [Homo sapiens]                       45   7e-04
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    45   7e-04
gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo...    45   7e-04
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]          45   7e-04
gi|194363768 homeobox D9 [Homo sapiens]                                44   0.001
gi|109255251 loricrin [Homo sapiens]                                   44   0.001
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    44   0.001
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]      44   0.001
gi|8051631 RNA binding protein (autoantigenic, hnRNP-associated ...    44   0.001
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 44   0.002
gi|239748639 PREDICTED: hypothetical protein XP_002346752 [Homo ...    44   0.002
gi|54860079 nadrin isoform 1 [Homo sapiens]                            44   0.002
gi|31657109 zinc finger protein 282 [Homo sapiens]                     44   0.002

>gi|29570782 additional sex combs like 1 [Homo sapiens]
          Length = 1541

 Score = 3102 bits (8041), Expect = 0.0
 Identities = 1541/1541 (100%), Positives = 1541/1541 (100%)

Query: 1    MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAML 60
            MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAML
Sbjct: 1    MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAML 60

Query: 61   HSNSRGGEGLFYKLPGRISLFTLKKDALQWSRHPATVEGEEPEDTADVESCGSNEASTVS 120
            HSNSRGGEGLFYKLPGRISLFTLKKDALQWSRHPATVEGEEPEDTADVESCGSNEASTVS
Sbjct: 61   HSNSRGGEGLFYKLPGRISLFTLKKDALQWSRHPATVEGEEPEDTADVESCGSNEASTVS 120

Query: 121  GENDVSLDETSSNASCSTESQSRPLSNPRDSYRASSQANKQKKKTGVMLPRVVLTPLKVN 180
            GENDVSLDETSSNASCSTESQSRPLSNPRDSYRASSQANKQKKKTGVMLPRVVLTPLKVN
Sbjct: 121  GENDVSLDETSSNASCSTESQSRPLSNPRDSYRASSQANKQKKKTGVMLPRVVLTPLKVN 180

Query: 181  GAHVESASGFSGCHADGESGSPSSSSSGSLALGSAAIRGQAEVTQDPAPLLRGFRKPATG 240
            GAHVESASGFSGCHADGESGSPSSSSSGSLALGSAAIRGQAEVTQDPAPLLRGFRKPATG
Sbjct: 181  GAHVESASGFSGCHADGESGSPSSSSSGSLALGSAAIRGQAEVTQDPAPLLRGFRKPATG 240

Query: 241  QMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGL 300
            QMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGL
Sbjct: 241  QMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGL 300

Query: 301  LRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYG 360
            LRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYG
Sbjct: 301  LRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYG 360

Query: 361  QKLGLTKEESLQQNVGQEEAEIKSGLCVPGESVRIQRGPATRQRDGHFKKRSRPDLRTRA 420
            QKLGLTKEESLQQNVGQEEAEIKSGLCVPGESVRIQRGPATRQRDGHFKKRSRPDLRTRA
Sbjct: 361  QKLGLTKEESLQQNVGQEEAEIKSGLCVPGESVRIQRGPATRQRDGHFKKRSRPDLRTRA 420

Query: 421  RRNLYKKQESEQAGVAKDAKSVASDVPLYKDGEAKTDPAGLSSPHLPGTSSAAPDLEGPE 480
            RRNLYKKQESEQAGVAKDAKSVASDVPLYKDGEAKTDPAGLSSPHLPGTSSAAPDLEGPE
Sbjct: 421  RRNLYKKQESEQAGVAKDAKSVASDVPLYKDGEAKTDPAGLSSPHLPGTSSAAPDLEGPE 480

Query: 481  FPVESVASRIQAEPDNLARASASPDRIPSLPQETVDQEPKDQKRKSFEQAASASFPEKKP 540
            FPVESVASRIQAEPDNLARASASPDRIPSLPQETVDQEPKDQKRKSFEQAASASFPEKKP
Sbjct: 481  FPVESVASRIQAEPDNLARASASPDRIPSLPQETVDQEPKDQKRKSFEQAASASFPEKKP 540

Query: 541  RLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPT 600
            RLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPT
Sbjct: 541  RLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPT 600

Query: 601  TESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGG 660
            TESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGG
Sbjct: 601  TESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGG 660

Query: 661  RGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARRED 720
            RGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARRED
Sbjct: 661  RGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARRED 720

Query: 721  LPSLRKEESCLLQRATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVEQPQ 780
            LPSLRKEESCLLQRATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVEQPQ
Sbjct: 721  LPSLRKEESCLLQRATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVEQPQ 780

Query: 781  LHPDVRTECESGTTSWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPTMKDP 840
            LHPDVRTECESGTTSWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPTMKDP
Sbjct: 781  LHPDVRTECESGTTSWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPTMKDP 840

Query: 841  VNVTPSSTPESSPTDCLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSLHWIP 900
            VNVTPSSTPESSPTDCLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSLHWIP
Sbjct: 841  VNVTPSSTPESSPTDCLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSLHWIP 900

Query: 901  IPSNDEVVKQPKPESREHIPSVEPQVGEEWEKAAPTPPALPGDLTAEEGLDPLDSLTSLW 960
            IPSNDEVVKQPKPESREHIPSVEPQVGEEWEKAAPTPPALPGDLTAEEGLDPLDSLTSLW
Sbjct: 901  IPSNDEVVKQPKPESREHIPSVEPQVGEEWEKAAPTPPALPGDLTAEEGLDPLDSLTSLW 960

Query: 961  TVPSRGGSDSNGSYCQQVDIEKLKINGDSEALSPHGESTDTASDFEGHLTEDSSEADTRE 1020
            TVPSRGGSDSNGSYCQQVDIEKLKINGDSEALSPHGESTDTASDFEGHLTEDSSEADTRE
Sbjct: 961  TVPSRGGSDSNGSYCQQVDIEKLKINGDSEALSPHGESTDTASDFEGHLTEDSSEADTRE 1020

Query: 1021 AAVTKGSSVDKDEKPNWNQSAPLSKVNGDMRLVTRTDGMVAPQSWVSRVCAVRQKIPDSL 1080
            AAVTKGSSVDKDEKPNWNQSAPLSKVNGDMRLVTRTDGMVAPQSWVSRVCAVRQKIPDSL
Sbjct: 1021 AAVTKGSSVDKDEKPNWNQSAPLSKVNGDMRLVTRTDGMVAPQSWVSRVCAVRQKIPDSL 1080

Query: 1081 LLASTEYQPRAVCLSMPGSSVEATNPLVMQLLQGSLPLEKVLPPAHDDSMSESPQVPLTK 1140
            LLASTEYQPRAVCLSMPGSSVEATNPLVMQLLQGSLPLEKVLPPAHDDSMSESPQVPLTK
Sbjct: 1081 LLASTEYQPRAVCLSMPGSSVEATNPLVMQLLQGSLPLEKVLPPAHDDSMSESPQVPLTK 1140

Query: 1141 DQSHGSLRMGSLHGLGKNSGMVDGSSPSSLRALKEPLLPDSCETGTGLARIEATQAPGAP 1200
            DQSHGSLRMGSLHGLGKNSGMVDGSSPSSLRALKEPLLPDSCETGTGLARIEATQAPGAP
Sbjct: 1141 DQSHGSLRMGSLHGLGKNSGMVDGSSPSSLRALKEPLLPDSCETGTGLARIEATQAPGAP 1200

Query: 1201 QKNCKAVPSFDSLHPVTNPITSSRKLEEMDSKEQFSSFSCEDQKEVRAMSQDSNSNAAPG 1260
            QKNCKAVPSFDSLHPVTNPITSSRKLEEMDSKEQFSSFSCEDQKEVRAMSQDSNSNAAPG
Sbjct: 1201 QKNCKAVPSFDSLHPVTNPITSSRKLEEMDSKEQFSSFSCEDQKEVRAMSQDSNSNAAPG 1260

Query: 1261 KSPGDLTTSRTPRFSSPNVISFGPEQTGRALGDQSNVTGQGKKLFGSGNVAATLQRPRPA 1320
            KSPGDLTTSRTPRFSSPNVISFGPEQTGRALGDQSNVTGQGKKLFGSGNVAATLQRPRPA
Sbjct: 1261 KSPGDLTTSRTPRFSSPNVISFGPEQTGRALGDQSNVTGQGKKLFGSGNVAATLQRPRPA 1320

Query: 1321 DPMPLPAEIPPVFPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEKTFVGGPLKA 1380
            DPMPLPAEIPPVFPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEKTFVGGPLKA
Sbjct: 1321 DPMPLPAEIPPVFPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEKTFVGGPLKA 1380

Query: 1381 NAENRKATGHSPLELVGHLEGMPFVMDLPFWKLPREPGKGLSEPLEPSSLPSQLSIKQAF 1440
            NAENRKATGHSPLELVGHLEGMPFVMDLPFWKLPREPGKGLSEPLEPSSLPSQLSIKQAF
Sbjct: 1381 NAENRKATGHSPLELVGHLEGMPFVMDLPFWKLPREPGKGLSEPLEPSSLPSQLSIKQAF 1440

Query: 1441 YGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSLQMFTDSSTVE 1500
            YGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSLQMFTDSSTVE
Sbjct: 1441 YGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSLQMFTDSSTVE 1500

Query: 1501 SISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR 1541
            SISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR
Sbjct: 1501 SISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR 1541


>gi|153792780 additional sex combs like 2 [Homo sapiens]
          Length = 1435

 Score =  381 bits (979), Expect = e-105
 Identities = 330/1022 (32%), Positives = 471/1022 (46%), Gaps = 120/1022 (11%)

Query: 1   MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAML 60
           M++K ++KK RTWAEAA+ VLE Y + PM+ K+ILQVI+ EGLKE+RSGTSPLACLNAML
Sbjct: 1   MREKGRRKKGRTWAEAAKTVLEKYPNTPMSHKEILQVIQREGLKEIRSGTSPLACLNAML 60

Query: 61  HSNSRGGEGLFYKLPGRISLFTLKKDALQWSRHPATVEGEEPEDTADVESCGSNEASTVS 120
           H+NSRG EG+FYK+PGR+ ++TLKKD     +  +    E  +  +D +S  ++ +S+  
Sbjct: 61  HTNSRGEEGIFYKVPGRMGVYTLKKDVPDGVKELSEGSEESSDGQSDSQSSENSSSSSDG 120

Query: 121 GEND----------VSLDETSSNASCSTESQSRPLS-NPRDSYRASSQANKQ---KKKTG 166
           G N           VS     S     T    + +S + + S +A  QA KQ   KK+  
Sbjct: 121 GSNKEGKKSRWKRKVSSSSPQSGCPSPTIPAGKVISPSQKHSKKALKQALKQQQQKKQQQ 180

Query: 167 VMLPRVVLTP-----LKVNGAHVESASG----FSGCHADGESGSPSSSSSGSLALGSAAI 217
              P + ++      LK   A  +S       + G  +DG++GSP +S+S      S+++
Sbjct: 181 QCRPSISISSNQHLSLKTVKAASDSVPAKPATWEGKQSDGQTGSPQNSNSSF----SSSV 236

Query: 218 RGQAEVTQDPAPLLRGFRKPATGQMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALP 277
           + +  +        +   +  T QMKR +  +ID ETP SILVNTNLRALIN  TF  LP
Sbjct: 237 KVENTLLGLGKKSFQRSERLHTRQMKRTKCADIDVETPDSILVNTNLRALINKHTFSVLP 296

Query: 278 SHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRI 337
              QQ+LL LLPEVDRQVG DGL++L+ SALNNEFFT AAQ W+ERL++GEFT EMQVRI
Sbjct: 297 GDCQQRLLLLLPEVDRQVGPDGLMKLNGSALNNEFFTSAAQGWKERLSEGEFTPEMQVRI 356

Query: 338 RQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQNVGQEEAEIKSGLCVPGESVRIQR 397
           RQE+EKEKKVE WKE+FFE YYGQ  GL+ E+S +      + ++K       +S+ +  
Sbjct: 357 RQEIEKEKKVEPWKEQFFESYYGQSSGLSLEDSKKLTASPSDPKVKKTPAEQPKSMPVSE 416

Query: 398 GPATRQRDGHFKKRSRPDLRTRARRNLYKKQESEQAGVAKDAKSVASDVPLYKDGEAKTD 457
               R      +   + +    +     +K+E E  G  +   S +S+ PL        +
Sbjct: 417 ASLIRIVPVVSQSECKEEALQMSSPG--RKEECESQGEVQPNFSTSSE-PLLSSALNTHE 473

Query: 458 PAGLSSPHLPGTSS-------AAPDLEGPEFPVESVASRIQAEPDNLARASASPDRIPSL 510
            + +     P            + + E  +  + + ++  ++E       S S  + P +
Sbjct: 474 LSSILPIKCPKDEDLLEQKPVTSAEQESEKNHLTTASNYNKSESQESLVTSPSKPKSPGV 533

Query: 511 ------------PQET---------VDQEPKDQKRKS--FEQAASASFPEKKPRLEDRQS 547
                       PQET         VDQ P+  KRKS   ++ A  S+ EK+PR+ + + 
Sbjct: 534 EKPIVKPTAGAGPQETNMKEPLATLVDQSPESLKRKSSLTQEEAPVSW-EKRPRVTENRQ 592

Query: 548 FRNTIESVHTEKPQP------TKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPTT 601
            +   +      PQP        +  KVPP++I +SRI P   +   P+ Q+ PR     
Sbjct: 593 HQQPFQ----VSPQPFLNRGDRIQVRKVPPLKIPVSRISP---MPFHPS-QVSPRARFPV 644

Query: 602 ESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGG---GPGGGGGGATDEG 658
             +    TGARTLADIKA+A  V+  R       AA  A   GG   GPG GGG    EG
Sbjct: 645 SITSPNRTGARTLADIKAKAQLVKAQRAAAAAAAAAAAAASVGGTIPGPGPGGGQGPGEG 704

Query: 659 GGRGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRT-QLLPPYPLNGEHTQAGTAMSRAR 717
           G   ++ G    +    E   GP+     T     T +LLP  P     ++  T  S+A+
Sbjct: 705 GEGQTARGGSPGSDRVSETGKGPTLELAGTGSRGGTRELLPCGPETQPQSETKTTPSQAQ 764

Query: 718 REDLPSLRKEESCLLQRATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVE 777
              +   +     L Q   V  T  +  A     +P   +      L  ++ +     V 
Sbjct: 765 PHSVSGAQ-----LQQTPPVPPTPAVSGACTSVPSPAHIEKLDNEKLNPTRATATVASVS 819

Query: 778 QPQLHPDVRTECESGTTSWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTG-------QA 830
            PQ     R E     T         GP + +   P+     D T+E   G        +
Sbjct: 820 HPQGPSSCRQEKAPSPT---------GPALISGASPV-HCAADGTVELKAGPSKNIPNPS 869

Query: 831 LDSHPTMKDPVNVTPSSTPESSPTDCLQNRAFDD---ELGLGGSCPPMRESDTRQENLKT 887
             S      PV VTPS       T  L+              GS PP            +
Sbjct: 870 ASSKTDASVPVAVTPSPLTSLLTTATLEKLPVPQVSATTAPAGSAPP------------S 917

Query: 888 KALVSNSSLHWIPIPSNDEVVKQPKPESREHIPSVEPQVGEEWE-KAAPTPPALPGDLTA 946
             L + SSL     P     +  P       IP+  P V +  + K  P    LP  LT 
Sbjct: 918 STLPAASSL---KTPGTSLNMNGPTLRPTSSIPANNPLVTQLLQGKDVPMEQILPKPLTK 974

Query: 947 EE 948
            E
Sbjct: 975 VE 976



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 37/60 (61%), Positives = 48/60 (80%)

Query: 1482 ASHSASLSLQMFTDSSTVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR 1541
            +SH  ++ +Q F++ +++E    +C C LKAMIMC+GCGAFCHDDCIGPSKLCV CLVVR
Sbjct: 1376 SSHGQTIPVQAFSEENSIEGTPSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLVVR 1435



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 32/83 (38%), Positives = 44/83 (53%), Gaps = 12/83 (14%)

Query: 1077 PDSLLLASTEYQPRAVCLSM------PGSSVEATNPLVMQLLQG-SLPLEKVLPPAHDDS 1129
            P S L A++  +     L+M      P SS+ A NPLV QLLQG  +P+E++LP     +
Sbjct: 916  PSSTLPAASSLKTPGTSLNMNGPTLRPTSSIPANNPLVTQLLQGKDVPMEQILPKPL--T 973

Query: 1130 MSESPQVPLTKDQSHGSLRMGSL 1152
              E   VPLT  +  G   MG+L
Sbjct: 974  KVEMKTVPLTAKEERG---MGAL 993


>gi|149944526 additional sex combs like 3 [Homo sapiens]
          Length = 2248

 Score =  335 bits (859), Expect = 2e-91
 Identities = 300/988 (30%), Positives = 440/988 (44%), Gaps = 148/988 (14%)

Query: 1   MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAML 60
           MKDK +KKK+RTWAEAARL LE + ++PMT KQIL+VI+ EGLKE  SGTSPLACLNAML
Sbjct: 1   MKDK-RKKKDRTWAEAARLALEKHPNSPMTAKQILEVIQKEGLKET-SGTSPLACLNAML 58

Query: 61  HSNSRGGEGLFYKLPGRISLFTLKKDALQWSRHPATVEGEEPED-------TADVESCGS 113
           H+N+R G+G F+K+PG+  L+ LKK+           E   P D        ++++    
Sbjct: 59  HTNTRIGDGTFFKIPGKSGLYALKKE-----------ESSCPADGTLDLVCESELDGTDM 107

Query: 114 NEASTVSGENDVSLDETSSNASCSTES-------QSRPLSN-PRDSYRASSQA--NKQKK 163
            EA+    EN V   + +  AS + +S       QS+ +S+  + + +A  QA   +QK+
Sbjct: 108 AEANAHGEENGVCSKQVTDEASSTRDSSLTNTAVQSKLVSSFQQHTKKALKQALRQQQKR 167

Query: 164 KTGVML------PRVVLTPLKVNGAHVESASGFSGCHADGESGSPSSSSSGSLALGSAAI 217
           + GV +      PRVVLTPLKV+    +S SG    + + +S                  
Sbjct: 168 RNGVSMMVNKTVPRVVLTPLKVSDEQSDSPSGSESKNGEADSSDKEMK------------ 215

Query: 218 RGQAEVT-QDPAPLLRGFRKPATGQMKRNRGEEIDFETPGSILVNTNLRALINSRTFHAL 276
            GQ   T +  +  L+  +K   G +K  + E+ID ETPGSILVNTNLRALIN  TF +L
Sbjct: 216 HGQKSPTGKQTSQHLKRLKKSGLGHLKWTKAEDIDIETPGSILVNTNLRALINKHTFASL 275

Query: 277 PSHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVR 336
           P HFQQ LL LLPEVDRQ+G+DG+LRLS+SALNNEFF +AAQ W++RLA+GEFT EMQ+R
Sbjct: 276 PQHFQQYLLLLLPEVDRQMGSDGILRLSTSALNNEFFAYAAQGWKQRLAEGEFTPEMQLR 335

Query: 337 IRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQNVGQEEAEIKSGLCVPGESVRIQ 396
           IRQE+EKEKK E WKEKFFE +YG+KLG+++EES++   G   A  +S        + + 
Sbjct: 336 IRQEIEKEKKTEPWKEKFFERFYGEKLGMSREESVKLTTGPNNAGAQSSSSCGTSGLPVS 395

Query: 397 RGPA-TRQRDGHFKKRSRPDLRTRAR---------RNLYKKQESEQAGVAKD-------A 439
              A   Q+    K  + P+    A          +++  + ESE   + ++       A
Sbjct: 396 AQTALAEQQPKSMKSPASPEPGFCATLCPMVEIPPKDIMAELESEDILIPEESVIQEEIA 455

Query: 440 KSVASDVPLYKDGEAKTDPAGLSSPHLPGTSSAAPDLEGPEFPVESVASRIQAEPDNLAR 499
           + V + +   +D   KT P           S   P +  PE              DNL  
Sbjct: 456 EEVETSICECQDENHKTIPEFSEEAESLTNSHEEPQIAPPE--------------DNLES 501

Query: 500 ASASPDRIPSLPQETVDQEPKDQKRKSFEQAASASFPEKKPRLEDRQSFRNTIESVHTEK 559
                D + +LP   V  E K +  +                +    S  +  ++ H  K
Sbjct: 502 CVMMNDVLETLPHIEVKIEGKSESPQEEMTVVIDQLEVCDSLIPSTSSMTHVSDTEH--K 559

Query: 560 PQPTKEEPKVPPIRIQLSRIKPPWVVKG---------QPTYQICPR-IIPTTESSCRGWT 609
              T  E   P I+   S ++  +  +G          P  Q+     I  T  S     
Sbjct: 560 ESETAVETSTPKIKTGSSSLEGQFPNEGIAIDMELQSDPEEQLSENACISETSFSSESPE 619

Query: 610 GARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGG 669
           GA T       +L   G        E+ T A                +   + +S+ +  
Sbjct: 620 GACT-------SLPSPGGETQSTSEESCTPASLETTFCSEVSSTENTDKYNQRNSTDENF 672

Query: 670 EACGHPEPRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGT---AMSRARREDLPSLRK 726
            A    E      +P   + ++    L+   PL  E +           +   DLP L  
Sbjct: 673 HASLMSE-----ISPISTSPEISEASLMSNLPLTSEASPVSNLPLTSETSPMSDLP-LTS 726

Query: 727 EESCLLQRATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVEQPQLHPDVR 786
           E S +   +++ LT      S LP+      P +  P+  S +S+ ER+  Q +  P V 
Sbjct: 727 ETSSV---SSMLLTSETTFVSSLPL------PSETSPI--SNSSINERMAHQQRKSPSVS 775

Query: 787 TECESGTTSWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPTMKDPVNVTPS 846
            E  S        DE      P               E  T Q  +   T +  +  + S
Sbjct: 776 EEPLS-----PQKDESSATAKPLG-------------ENLTSQQKNLSNTPEPIIMSSSS 817

Query: 847 STPESSPTDCLQNRAF---------DDELGLGGSCPPMRESDTRQENLKTKALVSNSSLH 897
             PE+ P++ L N+           D E     S P +  + T    +K  +++  +   
Sbjct: 818 IAPEAFPSEDLHNKTLSQQTCKSHVDTEKPYPASIPEL--ASTEMIKVKNHSVLQRTEKK 875

Query: 898 WIPIPSNDEVVKQPKPESREHIPSVEPQ 925
            +P P    V  +        +PS + Q
Sbjct: 876 VLPSPLELSVFSEGTDNKGNELPSAKLQ 903



 Score =  110 bits (275), Expect = 1e-23
 Identities = 78/231 (33%), Positives = 111/231 (48%), Gaps = 21/231 (9%)

Query: 1317 PRPADPMPLPAEIPPV-FPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEKTFVG 1375
            P P  P PLP  +P    PS +  P     +    T R  W P+      ++K+E     
Sbjct: 2033 PPPPPPPPLPPPLPNAEVPSDQKQPPVTMET----TKRLSW-PQSTGICSNIKSEPLSFE 2087

Query: 1376 GPLKANAE-NRKATGHSPLELVGHLEGMPFVMDLPFWKLPREPGKGLSEPLEP----SSL 1430
              L ++ E   K   +   E+   L+           K        LSEP +P    ++ 
Sbjct: 2088 EGLSSSCELGMKQVSYDQNEMKEQLKAFAL-------KSADFSSYLLSEPQKPFTQLAAQ 2140

Query: 1431 PSQLSIKQAFYGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSL 1490
              Q+  +Q   G    +   STSF  ++S+     G+ GS    S+ A   +  +A + +
Sbjct: 2141 KMQVQQQQQLCGNYPTIHFGSTSFKRAASAIEKSIGILGSG---SNPATGLSGQNAQMPV 2197

Query: 1491 QMFTDSSTVESISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR 1541
            Q F DSS  + + L+C+C LKAMI+C+GCGAFCHDDCIGPSKLCV CLVVR
Sbjct: 2198 QNFADSSNADELELKCSCRLKAMIVCKGCGAFCHDDCIGPSKLCVACLVVR 2248



 Score =  106 bits (265), Expect = 2e-22
 Identities = 68/166 (40%), Positives = 88/166 (53%), Gaps = 8/166 (4%)

Query: 497  LARASASPDRIPSLPQETVDQEPKDQ---KRKSFEQAASASFPEKKPRLEDRQSFRNTIE 553
            L  +  S    PS   + +  E +D    KRK+ EQ +     EK+ R+ED QS RN   
Sbjct: 934  LETSHTSKSSEPSKSPDGIRNESRDSEISKRKTAEQHSFGICKEKRARIEDDQSTRNISS 993

Query: 554  SVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPTTESSCRGWTGART 613
            S   EK QP +EEP+VPP++IQLS+I PP+++K QP  +   R   +T  S    TGART
Sbjct: 994  SSPPEKEQPPREEPRVPPLKIQLSKIGPPFIIKSQPVSKPESRASTSTSVSGGRNTGART 1053

Query: 614  LADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGG 659
            LADIKARA Q R  R       AA  A+        G  G+  EGG
Sbjct: 1054 LADIKARAQQARAQR-----EAAAAAAVAAAASIVSGAMGSPGEGG 1094



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 106/494 (21%), Positives = 168/494 (34%), Gaps = 85/494 (17%)

Query: 675  PEPRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARREDLPSLRKEESCLLQR 734
            P P  G + P   TS +    L+PP  +N        A+  +  +   S+         R
Sbjct: 1342 PTPSIGNNLPNLSTSSV----LIPPMGINNRFPSEKIAIPGSEEQATVSMGTTV-----R 1392

Query: 735  ATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVEQPQLHPDVRTECESGTT 794
            A +  +D +     L   PT       + + +            P+L             
Sbjct: 1393 AALSCSDSVAVTDSLVAHPT-------VAMFTGNMLTINSYDSPPKL------------- 1432

Query: 795  SWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQAL------DSHPTMKDPVNVTPSST 848
            S ES D+  GP   ADN   P             +++      D   T+   +++T S  
Sbjct: 1433 SAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIVDHSTTLTSSLSLTVSVE 1492

Query: 849  PESSPTDCLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSLHWIPIPSNDEVV 908
               +  D LQ R    E  +     P     +R E +  + +  +S+         D   
Sbjct: 1493 SSEASLD-LQGRPVRTEASVQPVACPQVSVISRPEPVANEGIDHSSTFIAASAAKQDSKT 1551

Query: 909  KQPKPESREHIPSVEPQVGEEW--------EKAAPTPPALPGDLTAEEGLDPLDSLTSLW 960
                  S   +P V  ++ E          +   P P     D T     +P + +   W
Sbjct: 1552 LPATCTSLRELPLVPDKLNEPTAPSHNFAEQARGPAPFKSEADTTCSNQYNPSNRIC--W 1609

Query: 961  T----------VPSRGGSDSNGSYCQQVDIEKLKINGDS----EALSPHGESTDTASDFE 1006
                       + +  GS     Y +Q   + +K    +      L P    T+ A   +
Sbjct: 1610 NDDGMRSTGQPLVTHSGSSKQKEYLEQSCPKAIKTEHANYLNVSELHPRNLVTNVALPVK 1669

Query: 1007 GHLTEDSSEADTREAAVTKGSSVDKDEKPNWNQSAPLSKVNGDMRLVTRTDGMVAPQSWV 1066
              L     EAD       KG  +D ++ P      P ++       V +T  M A  S  
Sbjct: 1670 SEL----HEAD-------KGFRMDTEDFPGPELPPPAAEGASS---VQQTQNMKASTS-- 1713

Query: 1067 SRVCAVRQKIPDSLLLASTEYQ--PRAVCLSMPGSSVEATNPLVMQLLQGSLPLEKVLPP 1124
                     + +++ LA+   +  P A       SSVEA NPLV QLLQG+LPLEKVLP 
Sbjct: 1714 -------SPMEEAISLATDALKRVPGAGSSGCRLSSVEANNPLVTQLLQGNLPLEKVLPQ 1766

Query: 1125 AHDDSMSESPQVPL 1138
                +  E  ++PL
Sbjct: 1767 PRLGAKLEINRLPL 1780


>gi|9966841 cell death regulator aven [Homo sapiens]
          Length = 362

 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 103/374 (27%), Positives = 141/374 (37%), Gaps = 68/374 (18%)

Query: 625 RGARGHHCHRE----AATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGG 680
           RG  G   H E    AA  A GGGGG GG GGG    G GRG     GG   G   PRG 
Sbjct: 17  RGRPGGDRHSERPGAAAAVARGGGGGGGGDGGGRRGRGRGRGFRGARGGRG-GGGAPRGS 75

Query: 681 PSTPG--------KCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARREDLPSLRKEESCLL 732
              PG            D             G +++     +  R +D+      ES   
Sbjct: 76  RREPGGWGAGASAPVEDDSDAETYGEENDEQGNYSKRKIVSNWDRYQDIEKEVNNESGES 135

Query: 733 QRAT--VGLTDGLGDA-SQLPVAPTGDQPCQA-LPLLSSQTSV-AERLVEQPQ-----LH 782
           QR T    L    GD+ SQ   A   +   +A  P  +S   V +E LV   Q     L 
Sbjct: 136 QRGTDFSVLLSSAGDSFSQFRFAEEKEWDSEASCPKQNSAFYVDSELLVRALQELPLCLR 195

Query: 783 PDVRTECESGTTSWE--------SDD------EEQGPTVPADNGPIPSLVGDDTLEKGTG 828
            +V  E   GT   E        +DD      + +GP  P   GPI  L    ++  G  
Sbjct: 196 LNVAAELVQGTVPLEVPQVKPKRTDDGKGLGMQLKGPLGPGGRGPIFEL---KSVAAGC- 251

Query: 829 QALDSHPTMKDPVNVTPSSTPES-SPTDCLQNRA--FDDELGLGGSC-PPMRESDTRQEN 884
                 P +    N +P  + +S  PT  LQ+     ++EL L  +   P++E D    +
Sbjct: 252 ------PVLLGKDNPSPGPSRDSQKPTSPLQSAGDHLEEELDLLLNLDAPIKEGDNILPD 305

Query: 885 LKTKALVSNSSLHWIPIPSNDEVVKQPKPESREHIPSVEPQVGEEWEKAAPTPPALPGDL 944
             ++ L S           + EVV       +E     +P V EE +   P  P+   ++
Sbjct: 306 QTSQDLKSK---------EDGEVV-------QEEEVCAKPSVTEE-KNMEPEQPSTSKNV 348

Query: 945 TAEEGLDPLDSLTS 958
           T EE  D LDS+ S
Sbjct: 349 TEEELEDWLDSMIS 362


>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
           sapiens]
          Length = 443

 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 27/70 (38%), Positives = 33/70 (47%)

Query: 607 GWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSG 666
           G+  A++L      ALQ  G    H H+     + GGGGG GGGGGG    GGG G  S 
Sbjct: 33  GYREAQSLVQGDYGALQSNGHPLSHAHQWITALSHGGGGGGGGGGGGGGGGGGGGGDGSP 92

Query: 667 DGGEACGHPE 676
                 G P+
Sbjct: 93  WSTSPLGQPD 102


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
            [Homo sapiens]
          Length = 1412

 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 198/951 (20%), Positives = 331/951 (34%), Gaps = 150/951 (15%)

Query: 522  QKRKSFEQAASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKP 581
            +KRK+ E AA  +   KK R+ D  S   + E     + +  K  P++      +     
Sbjct: 61   RKRKAEEDAALQA---KKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADL 117

Query: 582  PWVVKGQPTYQICPRIIPTTESSCRGWTGARTLADIKARALQVRGARGH-------HCHR 634
            P  +K +   +   +   T  S     TG +T+A++ +     + A              
Sbjct: 118  PSSMKEKAKAET-EKAGKTGNSMPHPATG-KTVANLLSGKSPRKSAEPSANTTLVSETEE 175

Query: 635  EAATTAIGGGGGPGGGGGGATDEGGGRGSSSGD------------------GGEACGHPE 676
            E +  A G    PG    G  D      SSS D                     A G P 
Sbjct: 176  EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPG 235

Query: 677  PRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARREDLPSLRKEESCLLQRAT 736
                P+ PGK  +   +T+   P     E +++ +  S    E+ P+ +     LLQ   
Sbjct: 236  KGATPAPPGKAGAVASQTKAGKPE----EDSESSSEESSDSEEETPAAK----ALLQAKA 287

Query: 737  VGLTDGLGDASQLPVAPTGDQPCQ-ALPLLSSQTSVAERLVEQPQLHPDVRTECESGTTS 795
             G T  +G AS    AP  + P + A P    +T  A    +  +   D      S ++S
Sbjct: 288  SGKTSQVGAAS----APAKESPRKGAAPAPPGKTGPAVAKAQAGKREED------SQSSS 337

Query: 796  WESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPTMKDPVNVTPSSTPESSPTD 855
             ESD EE+ P     +G  P +               S P  + P      + P  +   
Sbjct: 338  EESDSEEEAPAQAKPSGKAPQV------------RAASAPAKESPRKGAAPAPPRKTGPA 385

Query: 856  CLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSLHWIPIPSNDEVVKQPKPES 915
              Q +    E     S     ESD+ +E     AL + ++    P+  + +V        
Sbjct: 386  AAQVQVGKQE---EDSRSSSEESDSDRE-----ALAAMNAAQVKPLGKSPQVK------- 430

Query: 916  REHIPSVEPQVGEEWEKAAPTPPALPGDLT--AEEGLDPLDSLTSLWTVPSRGGSDSNGS 973
                P+    +G   + A P PP   G  T  A+ G    DS +S     S   SDS+  
Sbjct: 431  ----PASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS-----SEESSDSSDG 481

Query: 974  YCQQVDIEKLKINGDSEALSPHGESTDTASDFEGHLTEDSSEADTREAAVTKGSSVDKDE 1033
                 ++         ++L    ++  T+S  +G   +    A   +A     +S   +E
Sbjct: 482  -----EVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 536

Query: 1034 KPNWNQSAPLSKVNGDMRLVTRTDGMVAPQSWVSRVCAVRQKIPDSLLLASTEYQPRAVC 1093
                + SA   +    M        +  PQ   ++ C  +         AS +  P  V 
Sbjct: 537  S---SDSADSEEAPAAMTAAQAKPALKIPQ---TKACPKKTN-----TTASAKVAPVRVG 585

Query: 1094 LSMPGSSVEATNPLVMQLLQGSLPLEK--VLPPAHDDSMSESPQVPLTKDQSHG-SLRMG 1150
               P  +  AT+P       GS P        PA D S SE      ++++  G ++ +G
Sbjct: 586  TQAPRKAGTATSP------AGSSPAVAGGTQRPAEDSSSSEESD---SEEEKTGLAVTVG 636

Query: 1151 SLHGLGKNSGMVDGSSP--SSLRALKEPLLPDSCETGTGLARIEATQAPGAPQKNCKAVP 1208
                +GK   +   S P   SL     P+LP   +TG  + +++A +   +     ++  
Sbjct: 637  QAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG--KTGPTVTQVKAEKQEDSESSEEES-- 692

Query: 1209 SFDSLHPVTNPITSSRKLEEMDSKEQFSSFSCEDQKEVRAMSQDSNSNAAPGK--SPGDL 1266
              DS     +P      +++  +K   ++      K   +      + AA  K  SP  +
Sbjct: 693  --DSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKV 750

Query: 1267 TTS-RTPRFSSPNVISFGP---EQTGRALGDQSNVTGQGKKLFGSGNVAATLQRPRPADP 1322
                R P+ S+  V++ GP      G+A+   +      ++  GS            +D 
Sbjct: 751  KPPVRNPQNST--VLARGPASVPSVGKAVATAAQAQTGPEEDSGSSE--------EESDS 800

Query: 1323 MPLPAEIPPVFPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEKTFVGGPLKANA 1382
                  +  V PSGK      +++   ++PR+  AP P          KT   GP  A A
Sbjct: 801  EEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG--------KT---GPSAAQA 849

Query: 1383 ENRKATGHSPLELVGHLEGMPFVMDLPFWKLPREPGKGLSEPLEPSSLPSQ 1433
              +  +G S  E     E    V      K P         P  P++ P+Q
Sbjct: 850  GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 900


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
            sapiens]
          Length = 1411

 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 198/951 (20%), Positives = 331/951 (34%), Gaps = 150/951 (15%)

Query: 522  QKRKSFEQAASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKP 581
            +KRK+ E AA  +   KK R+ D  S   + E     + +  K  P++      +     
Sbjct: 61   RKRKAEEDAALQA---KKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADL 117

Query: 582  PWVVKGQPTYQICPRIIPTTESSCRGWTGARTLADIKARALQVRGARGH-------HCHR 634
            P  +K +   +   +   T  S     TG +T+A++ +     + A              
Sbjct: 118  PSSMKEKAKAET-EKAGKTGNSMPHPATG-KTVANLLSGKSPRKSAEPSANTTLVSETEE 175

Query: 635  EAATTAIGGGGGPGGGGGGATDEGGGRGSSSGD------------------GGEACGHPE 676
            E +  A G    PG    G  D      SSS D                     A G P 
Sbjct: 176  EGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPG 235

Query: 677  PRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARREDLPSLRKEESCLLQRAT 736
                P+ PGK  +   +T+   P     E +++ +  S    E+ P+ +     LLQ   
Sbjct: 236  KGATPAPPGKAGAVASQTKAGKPE----EDSESSSEESSDSEEETPAAK----ALLQAKA 287

Query: 737  VGLTDGLGDASQLPVAPTGDQPCQ-ALPLLSSQTSVAERLVEQPQLHPDVRTECESGTTS 795
             G T  +G AS    AP  + P + A P    +T  A    +  +   D      S ++S
Sbjct: 288  SGKTSQVGAAS----APAKESPRKGAAPAPPGKTGPAVAKAQAGKREED------SQSSS 337

Query: 796  WESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPTMKDPVNVTPSSTPESSPTD 855
             ESD EE+ P     +G  P +               S P  + P      + P  +   
Sbjct: 338  EESDSEEEAPAQAKPSGKAPQV------------RAASAPAKESPRKGAAPAPPRKTGPA 385

Query: 856  CLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSLHWIPIPSNDEVVKQPKPES 915
              Q +    E     S     ESD+ +E     AL + ++    P+  + +V        
Sbjct: 386  AAQVQVGKQE---EDSRSSSEESDSDRE-----ALAAMNAAQVKPLGKSPQVK------- 430

Query: 916  REHIPSVEPQVGEEWEKAAPTPPALPGDLT--AEEGLDPLDSLTSLWTVPSRGGSDSNGS 973
                P+    +G   + A P PP   G  T  A+ G    DS +S     S   SDS+  
Sbjct: 431  ----PASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS-----SEESSDSSDG 481

Query: 974  YCQQVDIEKLKINGDSEALSPHGESTDTASDFEGHLTEDSSEADTREAAVTKGSSVDKDE 1033
                 ++         ++L    ++  T+S  +G   +    A   +A     +S   +E
Sbjct: 482  -----EVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE 536

Query: 1034 KPNWNQSAPLSKVNGDMRLVTRTDGMVAPQSWVSRVCAVRQKIPDSLLLASTEYQPRAVC 1093
                + SA   +    M        +  PQ   ++ C  +         AS +  P  V 
Sbjct: 537  S---SDSADSEEAPAAMTAAQAKPALKIPQ---TKACPKKTN-----TTASAKVAPVRVG 585

Query: 1094 LSMPGSSVEATNPLVMQLLQGSLPLEK--VLPPAHDDSMSESPQVPLTKDQSHG-SLRMG 1150
               P  +  AT+P       GS P        PA D S SE      ++++  G ++ +G
Sbjct: 586  TQAPRKAGTATSP------AGSSPAVAGGTQRPAEDSSSSEESD---SEEEKTGLAVTVG 636

Query: 1151 SLHGLGKNSGMVDGSSP--SSLRALKEPLLPDSCETGTGLARIEATQAPGAPQKNCKAVP 1208
                +GK   +   S P   SL     P+LP   +TG  + +++A +   +     ++  
Sbjct: 637  QAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG--KTGPTVTQVKAEKQEDSESSEEES-- 692

Query: 1209 SFDSLHPVTNPITSSRKLEEMDSKEQFSSFSCEDQKEVRAMSQDSNSNAAPGK--SPGDL 1266
              DS     +P      +++  +K   ++      K   +      + AA  K  SP  +
Sbjct: 693  --DSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKV 750

Query: 1267 TTS-RTPRFSSPNVISFGP---EQTGRALGDQSNVTGQGKKLFGSGNVAATLQRPRPADP 1322
                R P+ S+  V++ GP      G+A+   +      ++  GS            +D 
Sbjct: 751  KPPVRNPQNST--VLARGPASVPSVGKAVATAAQAQTGPEEDSGSSE--------EESDS 800

Query: 1323 MPLPAEIPPVFPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEKTFVGGPLKANA 1382
                  +  V PSGK      +++   ++PR+  AP P          KT   GP  A A
Sbjct: 801  EEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPG--------KT---GPSAAQA 849

Query: 1383 ENRKATGHSPLELVGHLEGMPFVMDLPFWKLPREPGKGLSEPLEPSSLPSQ 1433
              +  +G S  E     E    V      K P         P  P++ P+Q
Sbjct: 850  GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQ 900


>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
          Length = 532

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 40/120 (33%), Positives = 45/120 (37%), Gaps = 13/120 (10%)

Query: 555 VHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPTTESSCRGWTGARTL 614
           VH   PQ ++  P             PP +V         P   P + S+      A   
Sbjct: 414 VHESSPQGSESSPAASS---GYESSTPPGLVS--------PSAEPQSSSNLSPAAAAAAA 462

Query: 615 ADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGH 674
           A   A A      RG       A    GGG G GGGGGGA   GGG GSS G  G A GH
Sbjct: 463 AAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGA--GGGGGGSSGGGSGTAGGH 520



 Score = 41.2 bits (95), Expect = 0.008
 Identities = 24/49 (48%), Positives = 27/49 (55%), Gaps = 5/49 (10%)

Query: 636 AATTAI--GGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPS 682
           AA +A+  GGG G GG GGG+   GGG GS  G GG   G     GG S
Sbjct: 469 AAVSAVHRGGGSGSGGAGGGS---GGGSGSGGGGGGAGGGGGGSSGGGS 514



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 19/41 (46%), Positives = 22/41 (53%)

Query: 642 GGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPS 682
           G GG  GG GGG+   GGG G+  G GG + G     GG S
Sbjct: 481 GSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHS 521



 Score = 37.7 bits (86), Expect = 0.087
 Identities = 15/27 (55%), Positives = 17/27 (62%)

Query: 643 GGGGPGGGGGGATDEGGGRGSSSGDGG 669
           GGGG G GGGG    GGG G++ G  G
Sbjct: 496 GGGGGGAGGGGGGSSGGGSGTAGGHSG 522


>gi|21396480 RNA binding protein (autoantigenic, hnRNP-associated
           with lethal yellow) short isoform [Homo sapiens]
          Length = 290

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 62/238 (26%), Positives = 86/238 (36%), Gaps = 36/238 (15%)

Query: 490 IQAEPDNLARASASPDRIPSLPQETVD----QEPKDQKRKSFEQAASASFPEKKPRLEDR 545
           +Q   +  ARA+   +    L  +T+D     EPK  + K  ++AASA +     RL D 
Sbjct: 60  VQYSNERHARAAVLGENGRVLAGQTLDINMAGEPKPDRPKGLKRAASAIY-----RLFD- 113

Query: 546 QSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPTTESSC 605
             +R  +  V   +  P K     P + + L R      VK     ++  R    T SS 
Sbjct: 114 --YRGRLSPVPVPRAVPVKR----PRVTVPLVRR-----VKTNVPVKLFARSTAVTTSSA 162

Query: 606 RGWTGARTLADIKARALQVRGARGHHCHREAATTAI----------GGGGGPGGGGGGAT 655
           +    +  L  IK    Q++        R     A           G GGG GGGGGG  
Sbjct: 163 KIKLKSSELQAIKTELTQIKSNIDALLSRLEQIAAEQKANPDGKKKGDGGGAGGGGGGGG 222

Query: 656 DEGGGRGSSSGDGGEACGHPEPR-----GGPSTPGKCTSDLQRTQLLPPYPLNGEHTQ 708
             GGG G   G G      P+       G P    +   D     LL       EH+Q
Sbjct: 223 SGGGGSGGGGGGGSSRPPAPQENTTSEAGLPQGEARTRDDGDEEGLLTHSEEELEHSQ 280


>gi|13994190 frizzled 8 [Homo sapiens]
          Length = 694

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 20/31 (64%), Positives = 20/31 (64%)

Query: 636 AATTAIGGGGGPGGGGGGATDEGGGRGSSSG 666
           A  TA GGGGGPGGGGGG    GGG G   G
Sbjct: 633 AGATAAGGGGGPGGGGGGGPGGGGGPGGGGG 663



 Score = 35.8 bits (81), Expect = 0.33
 Identities = 18/36 (50%), Positives = 18/36 (50%)

Query: 645 GGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGG 680
           G   GGG GAT  GGG G   G GG   G   P GG
Sbjct: 626 GAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGG 661



 Score = 35.8 bits (81), Expect = 0.33
 Identities = 16/34 (47%), Positives = 17/34 (50%)

Query: 640 AIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACG 673
           A+GGG G    GGG    GGG G   G GG   G
Sbjct: 628 AVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGGG 661



 Score = 31.6 bits (70), Expect = 6.2
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 2/46 (4%)

Query: 624 VRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGG 669
           VR   GH   + A +    G GG GG GG A   G     + G GG
Sbjct: 329 VRLVAGHE--KVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGG 372



 Score = 31.2 bits (69), Expect = 8.1
 Identities = 15/36 (41%), Positives = 17/36 (47%), Gaps = 3/36 (8%)

Query: 644 GGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRG 679
           GG PG GG G     GG  + +G  G   G P  RG
Sbjct: 342 GGAPGAGGAGGA---GGAAAGAGAAGAGAGGPGGRG 374


>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
          Length = 753

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 128/619 (20%), Positives = 206/619 (33%), Gaps = 101/619 (16%)

Query: 337 IRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKE-------------------ESLQQNVGQ 377
           I  +ME+ K VE  +E   + Y  + LGL ++                   ++L   V Q
Sbjct: 84  IETQMERFKVVE--RETKTKAYSKEGLGLAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQ 141

Query: 378 EEAEIKSGLCVPGESVRIQRGPATRQRDGHFKKRSRPD-LRTRARRNLYKKQESEQAGVA 436
            E+E+        ES+ +Q    TR++ G   K+ R + L+    ++ Y  +  E     
Sbjct: 142 FESEV--------ESLSVQ----TRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRM 189

Query: 437 KDAKSVASDV--PLYKDGEAKTDPAGLSSPHLPGTSSAAPDLEGPEFPVESVA----SRI 490
            D  S+  D    +  D E   D +    P          DL+  + P   VA    S  
Sbjct: 190 LDNDSILVDAIRKIKDDVEYYVDSS--QDPDFEENEFLYDDLDLEDIPQALVATSPPSHS 247

Query: 491 QAEPDNLARASASPDR------IPSLPQETVDQEPKDQKRKSFEQAASASFPEKKPRLED 544
             E +   ++S++P        IP  P     +  +D K++     +  S    K   + 
Sbjct: 248 HMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKP 307

Query: 545 RQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPTTESS 604
             S      + H + P      P  PP         P     G P     P  +    S 
Sbjct: 308 VHS------NQHPQSPAVPPTYPSGPPPAASALSTTPG--NNGVPAPAAPPSALGPKASP 359

Query: 605 CRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSS 664
                        +A A            R  +    GGGGG  GGGG ++      G  
Sbjct: 360 APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG 419

Query: 665 SGDGGEACGHPE-PRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARREDLPS 723
           +G    A  +       P+     +S           P +G H               PS
Sbjct: 420 AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPP------------PS 467

Query: 724 LRKEESCLLQRATVGLTDGLGDAS-------QLPVAPTGDQPCQALPLLSSQTSVAERLV 776
             KE S        G+  G G+ S        LPV P    P    P  S   +    L 
Sbjct: 468 TSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNP----PSSPTPSFSDAKAAGALLN 523

Query: 777 EQPQLHPDVRTECESGTTSWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPT 836
             PQ       +     +S +S  E    +   ++ P+P+L                H T
Sbjct: 524 GPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIED-PVPTL----------------HLT 566

Query: 837 MKDPVNVTPSSTPESSPTDCLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSL 896
            +D + ++ +S P +S    LQ    +  L LG    P+      +E L  +A+   ++ 
Sbjct: 567 ERD-IILSSTSAPPASAQPPLQLSEVNIPLSLG--VCPLGPVPLTKEQLYQQAM-EEAAW 622

Query: 897 HWIPIPSNDEVVKQPKPES 915
           H +P PS+ E ++Q  P +
Sbjct: 623 HHMPHPSDSERIRQYLPRN 641


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 29/67 (43%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 627 ARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGK 686
           A G   H +AA    GGGGG GGGGGGA   GGG G   G      G    RG PS+   
Sbjct: 17  AAGSIVHSDAAGAGGGGGGGGGGGGGGA--GGGGGGMQPGSAAVTSG--AYRGDPSSVKM 72

Query: 687 CTSDLQR 693
             SD  +
Sbjct: 73  VQSDFMQ 79


>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
          Length = 558

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 19/37 (51%), Positives = 20/37 (54%)

Query: 636 AATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEAC 672
           A  T+ GGGGG GG GGG    G G G   G GG  C
Sbjct: 68  ATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNC 104



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 19/44 (43%), Positives = 20/44 (45%), Gaps = 10/44 (22%)

Query: 642 GGGGGPGGGGGG----------ATDEGGGRGSSSGDGGEACGHP 675
           G GGG GGGGGG          +   GGG G  S  GG A   P
Sbjct: 90  GNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTP 133



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 18/43 (41%), Positives = 19/43 (44%), Gaps = 11/43 (25%)

Query: 642 GGGGGPGGGGGGATDEGGG-----------RGSSSGDGGEACG 673
           GGGGG  G GGG    GGG            GS  G GG + G
Sbjct: 83  GGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAG 125



 Score = 32.0 bits (71), Expect = 4.8
 Identities = 20/67 (29%), Positives = 26/67 (38%), Gaps = 5/67 (7%)

Query: 626 GARGHHCHREAATTAIGGGGGPGG---GGG--GATDEGGGRGSSSGDGGEACGHPEPRGG 680
           G  G +C+   A  + G GGG GG   GGG   +T      GSSS     +         
Sbjct: 98  GGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSS 157

Query: 681 PSTPGKC 687
            S+   C
Sbjct: 158 SSSSSSC 164


>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
          Length = 706

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 19/37 (51%), Positives = 20/37 (54%)

Query: 636 AATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEAC 672
           A  T+ GGGGG GG GGG    G G G   G GG  C
Sbjct: 68  ATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNC 104



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 19/44 (43%), Positives = 20/44 (45%), Gaps = 10/44 (22%)

Query: 642 GGGGGPGGGGGG----------ATDEGGGRGSSSGDGGEACGHP 675
           G GGG GGGGGG          +   GGG G  S  GG A   P
Sbjct: 90  GNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTP 133



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 18/43 (41%), Positives = 19/43 (44%), Gaps = 11/43 (25%)

Query: 642 GGGGGPGGGGGGATDEGGG-----------RGSSSGDGGEACG 673
           GGGGG  G GGG    GGG            GS  G GG + G
Sbjct: 83  GGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAG 125



 Score = 32.0 bits (71), Expect = 4.8
 Identities = 20/67 (29%), Positives = 26/67 (38%), Gaps = 5/67 (7%)

Query: 626 GARGHHCHREAATTAIGGGGGPGG---GGG--GATDEGGGRGSSSGDGGEACGHPEPRGG 680
           G  G +C+   A  + G GGG GG   GGG   +T      GSSS     +         
Sbjct: 98  GGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSS 157

Query: 681 PSTPGKC 687
            S+   C
Sbjct: 158 SSSSSSC 164


>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
          Length = 504

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 19/37 (51%), Positives = 20/37 (54%)

Query: 636 AATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEAC 672
           A  T+ GGGGG GG GGG    G G G   G GG  C
Sbjct: 68  ATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNC 104



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 19/44 (43%), Positives = 20/44 (45%), Gaps = 10/44 (22%)

Query: 642 GGGGGPGGGGGG----------ATDEGGGRGSSSGDGGEACGHP 675
           G GGG GGGGGG          +   GGG G  S  GG A   P
Sbjct: 90  GNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTP 133



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 18/43 (41%), Positives = 19/43 (44%), Gaps = 11/43 (25%)

Query: 642 GGGGGPGGGGGGATDEGGG-----------RGSSSGDGGEACG 673
           GGGGG  G GGG    GGG            GS  G GG + G
Sbjct: 83  GGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAG 125



 Score = 32.0 bits (71), Expect = 4.8
 Identities = 20/67 (29%), Positives = 26/67 (38%), Gaps = 5/67 (7%)

Query: 626 GARGHHCHREAATTAIGGGGGPGG---GGG--GATDEGGGRGSSSGDGGEACGHPEPRGG 680
           G  G +C+   A  + G GGG GG   GGG   +T      GSSS     +         
Sbjct: 98  GGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSS 157

Query: 681 PSTPGKC 687
            S+   C
Sbjct: 158 SSSSSSC 164


>gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precursor
           [Homo sapiens]
          Length = 864

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 1/64 (1%)

Query: 607 GWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSG 666
           GWT +R  +    R+LQ     G  C    AT      GG GGGGG  T  GGG G   G
Sbjct: 276 GWT-SRAPSPQAGRSLQEGAEGGQGCSEAWATLGWAAAGGFGGGGGACTAGGGGGGYRGG 334

Query: 667 DGGE 670
           D  E
Sbjct: 335 DASE 338


>gi|33620755 YEATS domain containing 2 [Homo sapiens]
          Length = 1422

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 22/58 (37%), Positives = 28/58 (48%)

Query: 624 VRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGP 681
           +R     +    +A +   G GG GGGGGG     GG GS+ G GG A G  +   GP
Sbjct: 783 LRATNNANLQSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGP 840



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 16/28 (57%), Positives = 18/28 (64%), Gaps = 1/28 (3%)

Query: 642 GGGGGPGGGGGGATDEGGGRGSSSGDGG 669
           G GGG   GGGG T  GGG  S++G GG
Sbjct: 816 GSGGGGSTGGGGGT-AGGGTQSTAGPGG 842


>gi|238859557 regulatory factor X1 [Homo sapiens]
          Length = 979

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 636 AATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRTQ 695
           A  +   GGGG GGGGGG    GGG   S+G GG   G    +GG        S    T+
Sbjct: 374 AGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGGYMLGSASQSYSHTTR 433

Query: 696 LLP---PYPLNGEHTQAGTAMSRA 716
             P    + L+   T  G ++ R+
Sbjct: 434 ASPATVQWLLDNYETAEGVSLPRS 457


>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform b [Homo sapiens]
          Length = 373

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 27/66 (40%), Positives = 29/66 (43%), Gaps = 12/66 (18%)

Query: 627 ARGHHCHREA-------ATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACG-----H 674
           A GHH H  A       +  A  GG G  GGGG A+  GGG G   G GG A G     H
Sbjct: 188 AAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALH 247

Query: 675 PEPRGG 680
           P    G
Sbjct: 248 PHHAAG 253



 Score = 36.2 bits (82), Expect = 0.25
 Identities = 17/33 (51%), Positives = 18/33 (54%)

Query: 637 ATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGG 669
           A+   GGGGG GGGGGGA   GG        GG
Sbjct: 222 ASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGG 254



 Score = 31.2 bits (69), Expect = 8.1
 Identities = 20/62 (32%), Positives = 22/62 (35%)

Query: 619 ARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPR 678
           A A    G   HH H  AA        G  G  G A    GG G + G G  + G     
Sbjct: 171 AAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGG 230

Query: 679 GG 680
           GG
Sbjct: 231 GG 232


>gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform a [Homo sapiens]
          Length = 403

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 27/66 (40%), Positives = 29/66 (43%), Gaps = 12/66 (18%)

Query: 627 ARGHHCHREA-------ATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACG-----H 674
           A GHH H  A       +  A  GG G  GGGG A+  GGG G   G GG A G     H
Sbjct: 188 AAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALH 247

Query: 675 PEPRGG 680
           P    G
Sbjct: 248 PHHAAG 253



 Score = 36.2 bits (82), Expect = 0.25
 Identities = 17/33 (51%), Positives = 18/33 (54%)

Query: 637 ATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGG 669
           A+   GGGGG GGGGGGA   GG        GG
Sbjct: 222 ASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGG 254



 Score = 31.2 bits (69), Expect = 8.1
 Identities = 20/62 (32%), Positives = 22/62 (35%)

Query: 619 ARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPR 678
           A A    G   HH H  AA        G  G  G A    GG G + G G  + G     
Sbjct: 171 AAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGG 230

Query: 679 GG 680
           GG
Sbjct: 231 GG 232


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 44/205 (21%), Positives = 65/205 (31%), Gaps = 41/205 (20%)

Query: 642  GGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRTQLLPPYP 701
            GGGGG  GGGGG    GGG                  GG      C S L   + L  + 
Sbjct: 3507 GGGGGGSGGGGGGGGGGGG------------------GGSYHCLACESALCGEEALSQHL 3548

Query: 702  LNGEHTQAGTAMSRARREDLPSLRKEESCLLQRATVGLTDGLGDASQLPVAPTGDQPCQA 761
             +  H       +    ++ PSL    +C    +T   +     ++  P  P+   P  A
Sbjct: 3549 ESALHKHRTITRAARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSPPPPSAAAPSSA 3608

Query: 762  -----------------------LPLLSSQTSVAERLVEQPQLHPDVRTECESGTTSWES 798
                                    P LSS ++V         + P + T+  S  +  + 
Sbjct: 3609 SPHASRKSWPQVVSRASAAKPPSFPPLSSSSTVTSSSCSTSGVQPSMPTDDYSEESDTDL 3668

Query: 799  DDEEQGPTVPADNGPIPSLVGDDTL 823
              +  GP  P +    PS   D  L
Sbjct: 3669 SQKSDGPASPVEGPKDPSCPKDSGL 3693



 Score = 32.3 bits (72), Expect = 3.6
 Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 30/161 (18%)

Query: 427  KQESEQAGVAKDAKSVASDVPLYKDGEAKTDPA----------GLSSPHLPGTSSAAPDL 476
            K+ +E  G+A   + +  + PL         PA          GL+SP LPG + +   L
Sbjct: 3085 KKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSLPGFTPSNTAL 3144

Query: 477  EGPEFPVESVASRIQAEPDNLARASASPDRIPSLPQETVDQEPKDQKRKS--FEQAASAS 534
              P+               NL    ++    P LP   +  +P      S    QA  A 
Sbjct: 3145 TSPK--------------PNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAM 3190

Query: 535  FPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQ 575
             P++ P+ + +Q        V    P P  + P  P + +Q
Sbjct: 3191 GPQQPPQQQQQQQ----QPQVQQPPPPPAAQPPPTPQLPLQ 3227


>gi|194363768 homeobox D9 [Homo sapiens]
          Length = 352

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 48/152 (31%), Positives = 57/152 (37%), Gaps = 26/152 (17%)

Query: 642 GGGGGPGGGGGGATDEGGGRGSSSGDGGEACGH-----PEPRGGPS-TPGKCTSDLQRTQ 695
           GG GG GGGGGG    G GRG S G  G A G      PE R  P+      T+    T 
Sbjct: 128 GGAGGGGGGGGG----GPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTS 183

Query: 696 LLPPYPLNGEHTQAGTAMSRARREDLPSLRKEESC--LLQRATVGLTDGLGDASQLPVAP 753
           L      + + T+   A     RE   S   E SC   LQ      T G G  + +  A 
Sbjct: 184 L----SSSSKRTECSVA-----RESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAAT 234

Query: 754 -TG----DQPCQALPLLSSQTSVAERLVEQPQ 780
            TG       C   P+        E+   QPQ
Sbjct: 235 GTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQ 266



 Score = 31.6 bits (70), Expect = 6.2
 Identities = 23/62 (37%), Positives = 25/62 (40%), Gaps = 5/62 (8%)

Query: 640 AIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRTQLLPP 699
           A  GG GPG G G AT  GG     S +      HP P        K  S  Q+ QL P 
Sbjct: 219 AATGGTGPGAGIGAATGTGG-----SSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPN 273

Query: 700 YP 701
            P
Sbjct: 274 NP 275


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 22/46 (47%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 642 GGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGKC 687
           GGGGG GG GGG     GG GS  G  G  CG+    GG  + G C
Sbjct: 21  GGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGY--SGGGGYSGGGC 64



 Score = 40.4 bits (93), Expect = 0.013
 Identities = 20/44 (45%), Positives = 24/44 (54%)

Query: 642 GGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPG 685
           GGGG  GGG GG +  GGG G   G GG + G  +  GG  + G
Sbjct: 55  GGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSG 98



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 3/43 (6%)

Query: 644 GGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGK 686
           GGG  GGGGG +  GG   S SG G   C   + +  P+ P K
Sbjct: 273 GGGSSGGGGGGSSVGG---SGSGKGVPICHQTQQKQAPTWPSK 312



 Score = 36.2 bits (82), Expect = 0.25
 Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 6/50 (12%)

Query: 642 GGGGGPGGGGGGATDEGGGRGSSSG------DGGEACGHPEPRGGPSTPG 685
           GG GG GGG GG+    GG GSS G       GG   G     GG S+ G
Sbjct: 75  GGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGG 124



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 19/49 (38%), Positives = 21/49 (42%), Gaps = 10/49 (20%)

Query: 642 GGGGGPGGGG----------GGATDEGGGRGSSSGDGGEACGHPEPRGG 680
           GGGGG GGGG          GG++  G G     G  G  CG     GG
Sbjct: 24  GGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGG 72



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 16/32 (50%), Positives = 17/32 (53%)

Query: 642 GGGGGPGGGGGGATDEGGGRGSSSGDGGEACG 673
           GG  G GG GG      GG G SSG GG + G
Sbjct: 227 GGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSG 258



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 24/68 (35%), Positives = 26/68 (38%), Gaps = 4/68 (5%)

Query: 645 GGPGGGGGGATDEGGGRGSSSG--DGGEACGHPEPRGGPSTPGKCTSDLQRTQLLPPYPL 702
           GG  GGG G    GGG GS  G   GG  CG      G S  G  +S         P P 
Sbjct: 167 GGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGS--SGGSGSGYVSSQQVTQTSCAPQPS 224

Query: 703 NGEHTQAG 710
            G  +  G
Sbjct: 225 YGGGSSGG 232



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 18/39 (46%), Positives = 20/39 (51%), Gaps = 2/39 (5%)

Query: 642 GGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGG 680
           GGGGG  G GGG++  G G G     GG  CG     GG
Sbjct: 244 GGGGGSSGCGGGSS--GIGSGCIISGGGSVCGGGSSGGG 280



 Score = 34.3 bits (77), Expect = 0.96
 Identities = 14/26 (53%), Positives = 14/26 (53%)

Query: 643 GGGGPGGGGGGATDEGGGRGSSSGDG 668
           GGGG  GGG G    GGG  S  G G
Sbjct: 117 GGGGSSGGGSGCFSSGGGGSSGGGSG 142



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 23/55 (41%), Positives = 25/55 (45%), Gaps = 7/55 (12%)

Query: 626 GARGHHCHREAATTAIGGGGGP----GGGGGGATDEGGGRGSS---SGDGGEACG 673
           G+ G  C         GGG G     GGGGGG    GGG G S   SG GG + G
Sbjct: 45  GSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGG 99



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 11/42 (26%)

Query: 642 GGGGGPGGGGGGAT----------DEGGGRGS-SSGDGGEAC 672
           GGGGG GG GGG+             GGG G  SSG GG  C
Sbjct: 72  GGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGC 113



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 22/48 (45%), Positives = 24/48 (50%), Gaps = 4/48 (8%)

Query: 642 GGGGGPGGGGGGATDEGGGRG--SSSGDG--GEACGHPEPRGGPSTPG 685
           GGGG  GGG G  +  GGG G  SS G G  G   G     GG S+ G
Sbjct: 92  GGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGG 139



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 19/44 (43%), Positives = 20/44 (45%), Gaps = 3/44 (6%)

Query: 642 GGGGG---PGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPS 682
           GGG G    GGGG G    GGG  S  G G  + G     GG S
Sbjct: 98  GGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGS 141



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 17/44 (38%), Positives = 19/44 (43%)

Query: 626 GARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGG 669
           G  G  C       + GGG G    GGG +  GG    SSG GG
Sbjct: 107 GGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG 150



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 21/52 (40%), Positives = 23/52 (44%), Gaps = 8/52 (15%)

Query: 642 GGGGGPGGGGG-----GATDEGGGRGSSSGDGGEACGHP---EPRGGPSTPG 685
           GGGG  GGG G     G    GGG G  S  GG   G     +  GG S+ G
Sbjct: 117 GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGG 168



 Score = 32.3 bits (72), Expect = 3.6
 Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 4/46 (8%)

Query: 642 GGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGKC 687
           GGG G G  G G    GGG  S  G GG + G     GG    G C
Sbjct: 39  GGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSG----GGGGGGIGGC 80



 Score = 32.0 bits (71), Expect = 4.8
 Identities = 20/51 (39%), Positives = 23/51 (45%), Gaps = 3/51 (5%)

Query: 626 GARGHHCHREAATTAIGGGGGPG---GGGGGATDEGGGRGSSSGDGGEACG 673
           G+ G  C       + GG  G G    GGGG +  G G GSS G GG   G
Sbjct: 28  GSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIG 78



 Score = 31.6 bits (70), Expect = 6.2
 Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 19/65 (29%)

Query: 629 GHHCHREAATTAIGGGGG---PGGGG----------------GGATDEGGGRGSSSGDGG 669
           G  C       + GGG G    GGGG                GG++  G G  SS G GG
Sbjct: 125 GSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGG 184

Query: 670 EACGH 674
             CG+
Sbjct: 185 SVCGY 189



 Score = 31.2 bits (69), Expect = 8.1
 Identities = 21/79 (26%), Positives = 26/79 (32%), Gaps = 13/79 (16%)

Query: 626 GARGHHCHREAATTAIGGGGGPGGGGGGATDE-------------GGGRGSSSGDGGEAC 672
           G  G  C      +  GGG   G G G  + +             GGG     G GG  C
Sbjct: 181 GGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGC 240

Query: 673 GHPEPRGGPSTPGKCTSDL 691
                 GG S  G  +S +
Sbjct: 241 FSSGGGGGSSGCGGGSSGI 259


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 22/44 (50%), Positives = 22/44 (50%), Gaps = 8/44 (18%)

Query: 642 GGGGGPGGGGGGATDEGGGRGSSSGDGGEACG--------HPEP 677
           GGGGGPGGGGG     GGG G   G GG   G        HP P
Sbjct: 148 GGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHP 191



 Score = 40.0 bits (92), Expect = 0.017
 Identities = 24/47 (51%), Positives = 24/47 (51%), Gaps = 7/47 (14%)

Query: 637 ATTAIGGGG---GPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGG 680
           A  A GGGG   GPGGGGG     GGG G   G GG   G P   GG
Sbjct: 134 AGAAAGGGGAHDGPGGGGG----PGGGGGPGGGPGGGGGGGPGGGGG 176



 Score = 38.9 bits (89), Expect = 0.039
 Identities = 25/66 (37%), Positives = 27/66 (40%), Gaps = 7/66 (10%)

Query: 620 RALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRG 679
           +AL+      H      A  A  GG G   GGGGA D  GG G   G GG       P G
Sbjct: 109 QALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGG-------PGG 161

Query: 680 GPSTPG 685
           GP   G
Sbjct: 162 GPGGGG 167


>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
          Length = 1312

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 53/204 (25%), Positives = 85/204 (41%), Gaps = 33/204 (16%)

Query: 321 RERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQNVGQEEA 380
           + RL D +     + R + E E+E K +Q +E+             + E LQ+ + QE A
Sbjct: 427 QRRLEDMQALRREEERRQAEREQEYKRKQLEEQ------------RQSERLQRQLQQEHA 474

Query: 381 EIKSGLCVPGESVRIQRG------PATRQRDGHFKKRSRPDLRTRARRNLYKKQESEQAG 434
            +KS L    +  ++Q+       P  R+   H+ +   P     A +  + ++  E+  
Sbjct: 475 YLKS-LQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNP-----ADKPAWAREVEERTR 528

Query: 435 VAKDAKSVASDVPLYKDGEAKTDPAG---LSSPHLPGTSSAAPDLEGPEFPVESVASRIQ 491
           + K   S     PL K     T P      +SP  PG  S  P ++ P  P E     +Q
Sbjct: 529 MNKQQNS-----PLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLQ 583

Query: 492 AEPD-NLARASASPDRIPSLPQET 514
            +P  NLA   AS D  P++P  T
Sbjct: 584 DQPTRNLAAFPASHDPDPAIPAPT 607


>gi|8051631 RNA binding protein (autoantigenic, hnRNP-associated
           with lethal yellow) long isoform [Homo sapiens]
          Length = 306

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 61/246 (24%), Positives = 86/246 (34%), Gaps = 36/246 (14%)

Query: 490 IQAEPDNLARASASPDRIPSLPQETVD----QEPKDQKRKSFEQAASA-------SFPEK 538
           +Q   +  ARA+   +    L  +T+D     EPK  + K  ++AASA        +   
Sbjct: 60  VQYSNERHARAAVLGENGRVLAGQTLDINMAGEPKPDRPKGLKRAASAIYSGYIFDYDYY 119

Query: 539 KPRLEDRQ-SFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRI 597
           +    DR   +R  +  V   +  P K     P + + L R      VK     ++  R 
Sbjct: 120 RDDFYDRLFDYRGRLSPVPVPRAVPVKR----PRVTVPLVRR-----VKTNVPVKLFARS 170

Query: 598 IPTTESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAI----------GGGGGP 647
              T SS +    +  L  IK    Q++        R     A           G GGG 
Sbjct: 171 TAVTTSSAKIKLKSSELQAIKTELTQIKSNIDALLSRLEQIAAEQKANPDGKKKGDGGGA 230

Query: 648 GGGGGGATDEGGGRGSSSGDGGEACGHPEPR-----GGPSTPGKCTSDLQRTQLLPPYPL 702
           GGGGGG    GGG G   G G      P+       G P    +   D     LL     
Sbjct: 231 GGGGGGGGSGGGGSGGGGGGGSSRPPAPQENTTSEAGLPQGEARTRDDGDEEGLLTHSEE 290

Query: 703 NGEHTQ 708
             EH+Q
Sbjct: 291 ELEHSQ 296


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 25/99 (25%)

Query: 625 RGARGHHCHREAATTA----------------IGGGGGPGGG--GGGATDEGGGRGSSSG 666
           +G+ G+ C R+   TA                 GGG GPG G   GG  + GGG+GS SG
Sbjct: 538 QGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSG 597

Query: 667 DGGEACGHPEPRGGP----STPGKCTSDLQRTQLLPPYP 701
            G +  G    RG      S  GK T   Q+    PP P
Sbjct: 598 KGSDGDGE---RGKSLKKRSYFGKLTQSKQQQMPPPPPP 633



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 18/53 (33%), Positives = 24/53 (45%)

Query: 642 GGGGGPGGGGGGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRT 694
           G GGG G  G G++    G    SG+G  + G     G  S   +C+ D Q T
Sbjct: 500 GSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGT 552


>gi|239748639 PREDICTED: hypothetical protein XP_002346752 [Homo
           sapiens]
          Length = 286

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 26/65 (40%), Positives = 28/65 (43%)

Query: 611 ARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGE 670
           AR  A + A A       G      A    +GGG    GGGGG    GGGRGS  G GG 
Sbjct: 138 ARGAATLPAAAATTTALDGPGAGGGAEAQFLGGGRSSAGGGGGGGGGGGGRGSRRGRGGG 197

Query: 671 ACGHP 675
             G P
Sbjct: 198 ERGGP 202



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 16/34 (47%), Positives = 20/34 (58%)

Query: 638 TTAIGGGGGPGGGGGGATDEGGGRGSSSGDGGEA 671
           ++A GGGGG GGGGG  +  G G G   G   +A
Sbjct: 173 SSAGGGGGGGGGGGGRGSRRGRGGGERGGPRAQA 206



 Score = 34.3 bits (77), Expect = 0.96
 Identities = 34/120 (28%), Positives = 45/120 (37%), Gaps = 31/120 (25%)

Query: 636 AATTAIGGGGGPGGGG--------GGATDEGGGRGSSSGDGGEACGHPEPRGGPSTPGKC 687
           A TTA+ G   PG GG        GG +  GGG G   G GG   G    RGG    G  
Sbjct: 149 ATTTALDG---PGAGGGAEAQFLGGGRSSAGGGGGGGGGGGGR--GSRRGRGGGERGGPR 203

Query: 688 TSDLQRTQLLPPYPLNGEHTQAGTAMSRARREDLPSLRKEE----SCLLQRATVGLTDGL 743
              ++R              +      R RR  L  LR+ +    +  L+RA   + + L
Sbjct: 204 AQAVRR--------------RLSALRGRGRRRRLKRLRRAQETRGAAALERACASVREEL 249


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 71/313 (22%), Positives = 109/313 (34%), Gaps = 28/313 (8%)

Query: 1136 VPLTKDQSHGSLRMGSLHGLGKNSGMVDGSSPSSLRALKEPLLPDSCETGTGLARIEATQ 1195
            VPLT   S+ S   G+      +SG ++   P+S+  ++  L+      G  L   +A +
Sbjct: 455  VPLTTPSSNHSFHTGN----DSDSGTLERKRPASMAVMEGDLVKKE-SFGVKLMDFQAHR 509

Query: 1196 APGAPQKNCKAVPSFDSLHPVTNPIT---SSRKLEEMDSKEQFSSFSCEDQKEVRAMSQD 1252
              G   +     P+F    P T+  T   +  +     S+ + SS           + Q 
Sbjct: 510  RGGTLNRK-HISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQG 568

Query: 1253 SNSNAAPGKSPGDLTTSRTPRFSSPNV-ISFGPEQTGRALGDQSNVTGQGKKLFGSGNVA 1311
             +        P D  ++  P     N  I+ G  Q   A G      GQ     G     
Sbjct: 569  PSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHT 628

Query: 1312 ATLQRPRPADPMPLPAEIPPVFPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEK 1371
                  +PA   P P   PP  P G+      S SG  Q P    +PKP     S   + 
Sbjct: 629  LRRAVKKPAPAPPKPGNPPPGHPGGQ------SSSGTSQHP-PSLSPKPPTRSPSPPTQH 681

Query: 1372 T-----FVGGPLKANAENRKATGHSPLELVGHLEGMPFVMDLPFWKL-PREPGKGLSEPL 1425
            T         P + +A  R ++  SP++   H    P     P     P   G     P 
Sbjct: 682  TGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQG-----PP 736

Query: 1426 EPSSLPSQLSIKQ 1438
             P +LPS+  ++Q
Sbjct: 737  NPMALPSEHGLEQ 749


>gi|31657109 zinc finger protein 282 [Homo sapiens]
          Length = 671

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 35/112 (31%), Positives = 45/112 (40%), Gaps = 14/112 (12%)

Query: 555 VHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPTTESSCRGWTGARTL 614
           V    P P + +P+  P + QL         + QP  Q  P   P   +   G   +R L
Sbjct: 400 VKNPPPAPPQPQPQPQPPQPQL---------QSQPQPQSLP---PIAVAENPGGPPSRGL 447

Query: 615 ADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGGRGSSSG 666
            D   + L   G RG          + GGGGG GGGGGG  + G G G   G
Sbjct: 448 LDDGFQVLP--GERGSGEAPPGGDRSTGGGGGDGGGGGGGAEAGTGAGGGCG 497


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,318,217
Number of Sequences: 37866
Number of extensions: 3835553
Number of successful extensions: 27367
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 206
Number of HSP's successfully gapped in prelim test: 464
Number of HSP's that attempted gapping in prelim test: 19215
Number of HSP's gapped (non-prelim): 5107
length of query: 1541
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1426
effective length of database: 13,892,928
effective search space: 19811315328
effective search space used: 19811315328
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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