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Search of human proteins with 122937281
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
(435 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937281 solute carrier family 38, member 8 [Homo sapiens] 872 0.0
gi|8922692 solute carrier family 38, member 7 [Homo sapiens] 338 4e-93
gi|117168277 amino acid transporter system A1 [Homo sapiens] 106 4e-23
gi|117168275 amino acid transporter system A1 [Homo sapiens] 106 4e-23
gi|193788624 solute carrier family 38, member 5 [Homo sapiens] 106 4e-23
gi|21361602 solute carrier family 38, member 2 [Homo sapiens] 106 5e-23
gi|24429574 solute carrier family 38, member 6 [Homo sapiens] 105 6e-23
gi|5870893 solute carrier family 38, member 3 [Homo sapiens] 103 4e-22
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ... 87 3e-17
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ... 87 3e-17
gi|27735137 solute carrier family 38, member 11 [Homo sapiens] 73 4e-13
gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo ... 65 2e-10
gi|219689132 solute carrier family 38, member 4 [Homo sapiens] 60 5e-09
gi|18482385 solute carrier family 38, member 4 [Homo sapiens] 60 5e-09
gi|222418631 solute carrier family 36, member 2 [Homo sapiens] 58 2e-08
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ... 56 7e-08
gi|41352721 solute carrier family 36 member 1 [Homo sapiens] 56 7e-08
gi|222418629 solute carrier family 38, member 9 [Homo sapiens] 55 1e-07
gi|17999520 solute carrier family 32, member 1 [Homo sapiens] 49 9e-06
gi|21389443 transmembrane protein 125 [Homo sapiens] 33 0.39
gi|23592222 olfactory receptor, family 5, subfamily P, member 2 ... 33 0.66
gi|31542943 solute carrier family 35, member F2 [Homo sapiens] 32 1.1
gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo ... 30 3.3
gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo ... 30 3.3
gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo ... 30 3.3
gi|197927133 hypothetical protein LOC84970 isoform a [Homo sapiens] 29 7.3
>gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
Length = 435
Score = 872 bits (2253), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MEGQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFL 60
MEGQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFL
Sbjct: 1 MEGQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFL 60
Query: 61 VELVSLVFLISGLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFL 120
VELVSLVFLISGLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFL
Sbjct: 61 VELVSLVFLISGLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFL 120
Query: 121 RVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILG 180
RVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILG
Sbjct: 121 RVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILG 180
Query: 181 TLAACYLALVITVQYYLWPQGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYC 240
TLAACYLALVITVQYYLWPQGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYC
Sbjct: 181 TLAACYLALVITVQYYLWPQGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYC 240
Query: 241 SMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARV 300
SMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARV
Sbjct: 241 SMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARV 300
Query: 301 LFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLA 360
LFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLA
Sbjct: 301 LFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLA 360
Query: 361 MALFMPDLSEIVSIIGGISSFFIFIFPGLCLICAMGVEPIGPRVKCCLEVWGVVSVLVGT 420
MALFMPDLSEIVSIIGGISSFFIFIFPGLCLICAMGVEPIGPRVKCCLEVWGVVSVLVGT
Sbjct: 361 MALFMPDLSEIVSIIGGISSFFIFIFPGLCLICAMGVEPIGPRVKCCLEVWGVVSVLVGT 420
Query: 421 FIFGQSTAAAVWEMF 435
FIFGQSTAAAVWEMF
Sbjct: 421 FIFGQSTAAAVWEMF 435
>gi|8922692 solute carrier family 38, member 7 [Homo sapiens]
Length = 462
Score = 338 bits (868), Expect = 4e-93
Identities = 177/413 (42%), Positives = 254/413 (61%), Gaps = 8/413 (1%)
Query: 23 TLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAAAV 82
T S++GA+FI++ + LGAGLLNFP AFS AGGV +++ LVF+ISGLVIL Y +
Sbjct: 50 TTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQA 109
Query: 83 SGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAP 142
S + TYQ VV +CG G LCE + +AFL +IGDQ +K+ + A
Sbjct: 110 SNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGAS 169
Query: 143 QPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGL 202
PWY D++FT+ L + L ILPLS PREI FQKY S L + Y+ ++ ++ Y+WP
Sbjct: 170 GPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIK-YIWPDKE 228
Query: 203 VRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACC 262
+ + PASW +VF+ PTICFGFQCH ++V ++ SM++ + W V +++
Sbjct: 229 MTPGNILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIAL 288
Query: 263 LIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQ 322
+Y TG+ GFLTFG V DVL+SYP DM + VAR +S++T YPI+ F GR+V++
Sbjct: 289 AVYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVE 348
Query: 323 DFWRRSCLGGWGPSALADPSGLWVRMPL-TILWVTVTLAMALFMPDLSEIVSIIGGISSF 381
W R G D R L T++W +TL +ALF+PD+ +++S+IGG+++
Sbjct: 349 GLWLRY----QGVPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAAC 404
Query: 382 FIFIFPGLCLICA--MGVEPIGPRVKCCLEVWGVVSVLVGTFIFGQSTAAAVW 432
FIF+FPGLCLI A +E + P L +GV+ V +G FIFGQ+TA A++
Sbjct: 405 FIFVFPGLCLIQAKLSEMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIF 457
>gi|117168277 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 106 bits (265), Expect = 4e-23
Identities = 89/380 (23%), Positives = 173/380 (45%), Gaps = 33/380 (8%)
Query: 25 SSMG-AVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFL-ISGLVILGYAAAV 82
+S+G +VF L + +G+G+L +A + G + FLV L S+ L I + +L +
Sbjct: 71 TSLGMSVFNLSNAIMGSGILGLAFALANTG--ILLFLVLLTSVTLLSIYSINLLLICSKE 128
Query: 83 SGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAP 142
+G Y+ + + G + L +++L ++ ++L L+ G
Sbjct: 129 TGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLM-GKEETF 187
Query: 143 QPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGL 202
WY D R + +++ +ILPL + + + YTS + +V+ + + P +
Sbjct: 188 SAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPC-I 246
Query: 203 VRESHPSLSPASWTS-------------VFSVFPTICFGFQCHEAAVSIYCSMRKRSLSH 249
V E + ++S S + PTI F F CH + + IY ++ RS
Sbjct: 247 VPELNSTISANSTNADTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKK 306
Query: 250 WALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPG-NDMVIIVARVLFAVSIVT 308
+VS +S A ++Y LT ++G+LTF V +D+L Y +D++I+ R+ V+++
Sbjct: 307 MQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAVIVAVIL 366
Query: 309 VYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDL 368
P++ F RS + + +++ L +T + + V + +F+P +
Sbjct: 367 TVPVLFFTVRSSLFELAKKT------------KFNLCRHTVVTCILLVVINLLVIFIPSM 414
Query: 369 SEIVSIIGGIS-SFFIFIFP 387
+I ++G S + IFI P
Sbjct: 415 KDIFGVVGVTSANMLIFILP 434
>gi|117168275 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 106 bits (265), Expect = 4e-23
Identities = 89/380 (23%), Positives = 173/380 (45%), Gaps = 33/380 (8%)
Query: 25 SSMG-AVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFL-ISGLVILGYAAAV 82
+S+G +VF L + +G+G+L +A + G + FLV L S+ L I + +L +
Sbjct: 71 TSLGMSVFNLSNAIMGSGILGLAFALANTG--ILLFLVLLTSVTLLSIYSINLLLICSKE 128
Query: 83 SGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAP 142
+G Y+ + + G + L +++L ++ ++L L+ G
Sbjct: 129 TGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLM-GKEETF 187
Query: 143 QPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGL 202
WY D R + +++ +ILPL + + + YTS + +V+ + + P +
Sbjct: 188 SAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPC-I 246
Query: 203 VRESHPSLSPASWTS-------------VFSVFPTICFGFQCHEAAVSIYCSMRKRSLSH 249
V E + ++S S + PTI F F CH + + IY ++ RS
Sbjct: 247 VPELNSTISANSTNADTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKK 306
Query: 250 WALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPG-NDMVIIVARVLFAVSIVT 308
+VS +S A ++Y LT ++G+LTF V +D+L Y +D++I+ R+ V+++
Sbjct: 307 MQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAVIVAVIL 366
Query: 309 VYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDL 368
P++ F RS + + +++ L +T + + V + +F+P +
Sbjct: 367 TVPVLFFTVRSSLFELAKKT------------KFNLCRHTVVTCILLVVINLLVIFIPSM 414
Query: 369 SEIVSIIGGIS-SFFIFIFP 387
+I ++G S + IFI P
Sbjct: 415 KDIFGVVGVTSANMLIFILP 434
>gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
Length = 472
Score = 106 bits (265), Expect = 4e-23
Identities = 106/444 (23%), Positives = 192/444 (43%), Gaps = 49/444 (11%)
Query: 3 GQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVE 62
G PGS+ + + +S VF L + +G+G+L +A + G + FL
Sbjct: 31 GPAPGSKPVQFMDFEGKTSFGMS----VFNLSNAIMGSGILGLAYAMAHTGVIF--FLAL 84
Query: 63 LVSLVFLIS-GLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLR 121
L+ + L S + +L A ++G Y+ + + GPA + L+ + ++L
Sbjct: 85 LLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLF 144
Query: 122 VIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGT 181
+I +L + + L P W+ + ++SVL+ILPL+ + + + YTS G
Sbjct: 145 IIKSELPLVIGTFLYMDPEGD--WFLKGNLLIIIVSVLIILPLALMKHLGYLGYTS--GL 200
Query: 182 LAACYLALVITVQYYLWPQG--------------LVRESHPSLSPASWTSVFSV------ 221
C L +++V Y + G LV L+ + +F+V
Sbjct: 201 SLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSY 260
Query: 222 -FPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEV 280
P + F F CH + IY + + S V+ +S+ A +Y LT +G+LTF + V
Sbjct: 261 TVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSV 320
Query: 281 SADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALAD 340
A++L Y D +I+ R+ +++ P+VLF R +Q W P +A
Sbjct: 321 KAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSW-PRHVA- 378
Query: 341 PSGLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGISS-FFIFIFPGL--CLICAMGV 397
+ ++ + + + + +P + +I +IG S+ IFI P + I V
Sbjct: 379 ---------IALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEV 429
Query: 398 EPI--GPRVKC-CLEVWGVVSVLV 418
EP P+++ C V GV+ + V
Sbjct: 430 EPFLSWPKIQALCFGVLGVLFMAV 453
>gi|21361602 solute carrier family 38, member 2 [Homo sapiens]
Length = 506
Score = 106 bits (264), Expect = 5e-23
Identities = 110/451 (24%), Positives = 194/451 (43%), Gaps = 58/451 (12%)
Query: 16 HPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVI 75
HP T + +S VF L + +G+G+L +A + G + L+ VS+ L S ++
Sbjct: 67 HPGTTSFGMS----VFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLL 122
Query: 76 LGYAAAVSGQATYQGVVRGLCGPAIGKLCEA--CFLLNLLMISVAFLRVIGDQLEKLCDS 133
L A G Y+ + G +GKL + + N+ +S ++L ++ +L + +
Sbjct: 123 LK-TANEGGSLLYEQLGYKAFG-LVGKLAASGSITMQNIGAMS-SYLFIVKYELPLVIQA 179
Query: 134 LLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITV 193
L + WY + + + L+S++VILPLS R + + YTS L L + +V+
Sbjct: 180 L-TNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVIC 238
Query: 194 QYY--------------------LWPQGLVRE-SHPSLSPASWTSVFSVF--------PT 224
+ + P LV SH S + +F P
Sbjct: 239 KKFQVPCPVEAALIINETINTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPI 298
Query: 225 ICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADV 284
+ F F CH A + IY ++ RS VS +S A L+Y L ++G+LTF V +++
Sbjct: 299 LIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESEL 358
Query: 285 LMSYP---GNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADP 341
L +Y G D+++++ R+ +++ P+V+F RS + S W
Sbjct: 359 LHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIRSSVTHLLCASKDFSW-------- 410
Query: 342 SGLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIG-GISSFFIFIFPGLCLICAMGVEPI 400
W +T+ + T + +F+P + +I IG +S IFI P I + EP
Sbjct: 411 ---WRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLVKKEP- 466
Query: 401 GPRVKCCLEVWGVVSVLVGTFIFGQSTAAAV 431
+K ++ + +L G + S A V
Sbjct: 467 ---MKSVQKIGALFFLLSGVLVMTGSMALIV 494
>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
Length = 456
Score = 105 bits (263), Expect = 6e-23
Identities = 89/382 (23%), Positives = 176/382 (46%), Gaps = 39/382 (10%)
Query: 29 AVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYA--AAVSGQA 86
+VF LM + +G+G+L + + G +FL+ V+L+ S ++L AV+
Sbjct: 50 SVFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYE 109
Query: 87 TYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWY 146
GL G + + + N+ +S ++L +I +L L+G + WY
Sbjct: 110 DLGLFAFGLPGKLV--VAGTIIIQNIGAMS-SYLLIIKTELPAAIAEFLTGD--YSRYWY 164
Query: 147 ADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWP------- 199
D + L ++ V ++ PL+ +I F YTS L + ALV+ ++ + P
Sbjct: 165 LDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNY 224
Query: 200 -------QGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWAL 252
+ + P L S S +++ PT+ F F CH + + IYC ++ S
Sbjct: 225 VEKGFQISNVTDDCKPKLFHFSKESAYAL-PTMAFSFLCHTSILPIYCELQSPSKKRMQN 283
Query: 253 VSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYP---GNDMVIIVARVLFAVSIVTV 309
V+ ++ LIY ++ ++G+LTF +V +++L Y +D+V++ ++ +++
Sbjct: 284 VTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLT 343
Query: 310 YPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLA-MALFMPDL 368
P++ F R + + ++ W+R L L + + + +A+++PD+
Sbjct: 344 VPLIHFPARKAVTMMF------------FSNFPFSWIRHFLITLALNIIIVLLAIYVPDI 391
Query: 369 SEIVSIIG-GISSFFIFIFPGL 389
+ ++G S+ IFIFPGL
Sbjct: 392 RNVFGVVGASTSTCLIFIFPGL 413
>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
Length = 504
Score = 103 bits (256), Expect = 4e-22
Identities = 106/434 (24%), Positives = 188/434 (43%), Gaps = 53/434 (12%)
Query: 1 MEGQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFL 60
MEG++ + ++PH S +VF L + +G+G+L +A + G ++ FL
Sbjct: 43 MEGKSFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFL 102
Query: 61 VELVSLVFLISGLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFL-LNLLMISVAF 119
+ V+L+ S ++L + V +A Q R P GKL A + L + ++
Sbjct: 103 LTAVALLSSYSIHLLLKSSGVVGIRAYEQLGYRAFGTP--GKLAAALAITLQNIGAMSSY 160
Query: 120 LRVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSIL 179
L +I +L + + L+ WY + + + L+SV +ILPL+ R++ + Y+S
Sbjct: 161 LYIIKSELPLVIQTFLN-LEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSS-- 217
Query: 180 GTLAACYLALVITVQYYLW------PQG------------LVRES-----HPSLSPASWT 216
G +C + +I V Y + P +V+E P S
Sbjct: 218 GFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTP 277
Query: 217 SVFSV-------FPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTG 269
S F++ P + F F CH + IY ++ S +S LS+ ++Y L
Sbjct: 278 SYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAA 337
Query: 270 VYGFLTFGTEVSADVLMSY---PGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWR 326
++G+LTF V +++L +Y D++I+ RV ++ PIVLF R +Q
Sbjct: 338 LFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQM-- 395
Query: 327 RSCLGGWGPSALADPSGLWVR-MPLTILWVTVTLAMALFMPDLSEIVSIIGGISS-FFIF 384
+ W+R + + + +T + +F P++ I +IG S+ F IF
Sbjct: 396 ----------LFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIF 445
Query: 385 IFPGLCLICAMGVE 398
IFP + M E
Sbjct: 446 IFPAIFYFRIMPTE 459
>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
sapiens]
Length = 1119
Score = 87.0 bits (214), Expect = 3e-17
Identities = 87/380 (22%), Positives = 169/380 (44%), Gaps = 29/380 (7%)
Query: 21 AATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAA 80
AA S+ G + ++ S +G +L P+ F + G V+ A L+ S + S + ++ +A
Sbjct: 3 AAAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVK-SA 61
Query: 81 AVSGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQ----LEKLCDSLLS 136
++S + TY G+ G A L E + +L +AF VIGD +L +
Sbjct: 62 SLSKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVG 121
Query: 137 GTPPAPQPWYADQRFTLPLLSVLVILPLSAPREI--AFQKYTSILGTLAACYLALVI--T 192
GT + F L +S+ ++LPLS R + + Q ++++ ++ +++ +
Sbjct: 122 GT---------FRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSS 172
Query: 193 VQYYLWPQGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWAL 252
+++ L+ +R +S W VF P F C + Y S+ + S+ +
Sbjct: 173 LKHGLFSGQWLRR----VSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSS 228
Query: 253 VSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPI 312
+ SL Y + G +G+++F + +VLM +P N +V + RV F +S+ +P+
Sbjct: 229 IFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSN-LVTEMLRVGFMMSVAVGFPM 287
Query: 313 VLFLGRSVMQDFW--RRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDLSE 370
++ R + ++ G + P LT+ V T+ + +P++
Sbjct: 288 MILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRF---KALTLSVVFGTMVGGILIPNVET 344
Query: 371 IVSIIGG-ISSFFIFIFPGL 389
I+ + G + S FI P L
Sbjct: 345 ILGLTGATMGSLICFICPAL 364
>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
sapiens]
Length = 780
Score = 87.0 bits (214), Expect = 3e-17
Identities = 87/380 (22%), Positives = 169/380 (44%), Gaps = 29/380 (7%)
Query: 21 AATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAA 80
AA S+ G + ++ S +G +L P+ F + G V+ A L+ S + S + ++ +A
Sbjct: 3 AAAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVK-SA 61
Query: 81 AVSGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQ----LEKLCDSLLS 136
++S + TY G+ G A L E + +L +AF VIGD +L +
Sbjct: 62 SLSKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVG 121
Query: 137 GTPPAPQPWYADQRFTLPLLSVLVILPLSAPREI--AFQKYTSILGTLAACYLALVI--T 192
GT + F L +S+ ++LPLS R + + Q ++++ ++ +++ +
Sbjct: 122 GT---------FRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSS 172
Query: 193 VQYYLWPQGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWAL 252
+++ L+ +R +S W VF P F C + Y S+ + S+ +
Sbjct: 173 LKHGLFSGQWLRR----VSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSS 228
Query: 253 VSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPI 312
+ SL Y + G +G+++F + +VLM +P N +V + RV F +S+ +P+
Sbjct: 229 IFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSN-LVTEMLRVGFMMSVAVGFPM 287
Query: 313 VLFLGRSVMQDFW--RRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDLSE 370
++ R + ++ G + P LT+ V T+ + +P++
Sbjct: 288 MILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRF---KALTLSVVFGTMVGGILIPNVET 344
Query: 371 IVSIIGG-ISSFFIFIFPGL 389
I+ + G + S FI P L
Sbjct: 345 ILGLTGATMGSLICFICPAL 364
>gi|27735137 solute carrier family 38, member 11 [Homo sapiens]
Length = 384
Score = 73.2 bits (178), Expect = 4e-13
Identities = 80/348 (22%), Positives = 141/348 (40%), Gaps = 60/348 (17%)
Query: 54 GVVPAFLVELV---SLVFLISGLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFLL 110
G++ F V V SLV LI G A+SG TYQ +V G LL
Sbjct: 9 GILLLFWVSYVTDFSLVLLIKG-------GALSGTDTYQSLVNKTFG------FPGYLLL 55
Query: 111 NLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREI 170
++L F+ P+ + + F + L +V LPLS R I
Sbjct: 56 SVLQFLYPFI-------------------VDPENVFIGRHFIIGLSTVTFTLPLSLYRNI 96
Query: 171 AFQKYTSILGT-LAACYLALVITVQYYLWPQGLVRESHPSLSPASWT----SVFSVFPTI 225
A S++ T L L +V+ L P H + +W + +
Sbjct: 97 AKLGKVSLISTGLTTLILGIVMARAISLGP-------HIPKTEDAWVFAKPNAIQAVGVM 149
Query: 226 CFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVL 285
F F CH + +Y S+ + +++ W+ + +S++ I G+LTF D+
Sbjct: 150 SFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCGYLTFTGFTQGDLF 209
Query: 286 MSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLW 345
+Y ND ++ R + V+++ YP+ F+ R V+ + + GG S
Sbjct: 210 ENYCRNDDLVTFGRFCYGVTVILTYPMECFVTREVIANVF----FGGNLSSVF------- 258
Query: 346 VRMPLTILWVTVTLAMALFMPDLSEIVSIIGGI-SSFFIFIFPGLCLI 392
+ +T++ +TV ++L + L ++ + G + ++ IFI P C +
Sbjct: 259 -HIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYL 305
>gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
sapiens]
Length = 470
Score = 64.7 bits (156), Expect = 2e-10
Identities = 87/406 (21%), Positives = 166/406 (40%), Gaps = 53/406 (13%)
Query: 13 EKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISG 72
E HPA A LS M + L+K +G GLL P A AG +V + + ++ +
Sbjct: 32 ENVHPAGEAG-LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCM 90
Query: 73 LVILGYAAAVS----------GQATYQGVV----RGLCGPAIGKLCEACFLLNLLMISV- 117
+++L A +S G+AT G+ L A+ FLL + +
Sbjct: 91 VILLNCAQHLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFC 150
Query: 118 -AFLRVIGDQLEKLCD------------SLLSGTPPAPQPWYADQRFTLPLLSVLVILPL 164
+ + D L+++ + +L+ TP +Y LP L +LV
Sbjct: 151 SVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFY--MLIILPFLILLVF--- 205
Query: 165 SAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRESHPSLSPASWTSVFSVFPT 224
I K S+ TLA + + + +G+ S+ L A+W + F T
Sbjct: 206 -----IQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPSNLPLM-ANWKTFLLFFGT 259
Query: 225 ICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADV 284
F F+ + + M+ ++ V L + ++Y L G G++ FG++ A +
Sbjct: 260 AIFTFEGVGMVLPLKNQMKHP--QQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASI 317
Query: 285 LMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGL 344
++ P N + ++++++ I Y + + ++ F S +++ L
Sbjct: 318 TLNLP-NCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPF---------AISQVSESWAL 367
Query: 345 WVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGISSFFI-FIFPGL 389
+V + + V +T A+ +P L ++S++G +SS + I P L
Sbjct: 368 FVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPAL 413
>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 59.7 bits (143), Expect = 5e-09
Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 23/215 (10%)
Query: 223 PTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSA 282
P + F F CH + IY ++ RS VS +S+ ++Y L ++G+LTF EV
Sbjct: 337 PILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVED 396
Query: 283 DVLMSYP---GNDMVIIVARVLFAVSIVTVYPIVLF-LGRSVMQDFWRRSCLGGWGPSAL 338
++L +Y D+ +++ R+ V++ PIVLF + SV+ + +
Sbjct: 397 ELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFS------- 449
Query: 339 ADPSGLWVR-MPLTILWVTVTLAMALFMPDLSEIVSIIGGIS-SFFIFIFPGLCLICAMG 396
W+R + + + + + + +P + I IG S + IFI P + + +
Sbjct: 450 ------WIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVK 503
Query: 397 VEPIGPRVKCCLEVWGVVSVLVGTFIFGQSTAAAV 431
E K V ++ ++VG F S A +
Sbjct: 504 KETFRSPQK----VGALIFLVVGIFFMIGSMALII 534
Score = 42.7 bits (99), Expect = 6e-04
Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 10/184 (5%)
Query: 13 EKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISG 72
++ HP T + +SS F L + +G+G+L +A + G ++ ++ V+++ L S
Sbjct: 68 DEHHPGTTSFGMSS----FNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSV 123
Query: 73 LVILGYAAAVSGQATYQGVVRGLCG-PAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLC 131
++L A G Y+ + G P + + N+ +S ++L +I +L ++
Sbjct: 124 HLLLK-TAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMS-SYLFIIKYELPEVI 181
Query: 132 DSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVI 191
+ + G WY + + + +SV +ILPLS + + + YTS G C + V
Sbjct: 182 RAFM-GLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTS--GFSLTCMVFFVS 238
Query: 192 TVQY 195
V Y
Sbjct: 239 VVIY 242
>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 59.7 bits (143), Expect = 5e-09
Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 23/215 (10%)
Query: 223 PTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSA 282
P + F F CH + IY ++ RS VS +S+ ++Y L ++G+LTF EV
Sbjct: 337 PILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVED 396
Query: 283 DVLMSYP---GNDMVIIVARVLFAVSIVTVYPIVLF-LGRSVMQDFWRRSCLGGWGPSAL 338
++L +Y D+ +++ R+ V++ PIVLF + SV+ + +
Sbjct: 397 ELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFS------- 449
Query: 339 ADPSGLWVR-MPLTILWVTVTLAMALFMPDLSEIVSIIGGIS-SFFIFIFPGLCLICAMG 396
W+R + + + + + + +P + I IG S + IFI P + + +
Sbjct: 450 ------WIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVK 503
Query: 397 VEPIGPRVKCCLEVWGVVSVLVGTFIFGQSTAAAV 431
E K V ++ ++VG F S A +
Sbjct: 504 KETFRSPQK----VGALIFLVVGIFFMIGSMALII 534
Score = 42.7 bits (99), Expect = 6e-04
Identities = 44/184 (23%), Positives = 86/184 (46%), Gaps = 10/184 (5%)
Query: 13 EKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISG 72
++ HP T + +SS F L + +G+G+L +A + G ++ ++ V+++ L S
Sbjct: 68 DEHHPGTTSFGMSS----FNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSV 123
Query: 73 LVILGYAAAVSGQATYQGVVRGLCG-PAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLC 131
++L A G Y+ + G P + + N+ +S ++L +I +L ++
Sbjct: 124 HLLLK-TAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMS-SYLFIIKYELPEVI 181
Query: 132 DSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVI 191
+ + G WY + + + +SV +ILPLS + + + YTS G C + V
Sbjct: 182 RAFM-GLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTS--GFSLTCMVFFVS 238
Query: 192 TVQY 195
V Y
Sbjct: 239 VVIY 242
>gi|222418631 solute carrier family 36, member 2 [Homo sapiens]
Length = 483
Score = 57.8 bits (138), Expect = 2e-08
Identities = 60/279 (21%), Positives = 122/279 (43%), Gaps = 37/279 (13%)
Query: 153 LPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRE-SHPSLS 211
LP L +LV++ R + S+L ++ ++LVI +QY + +E PS
Sbjct: 209 LPFLVLLVLI-----RNLRILTIFSMLANISML-VSLVIIIQY------ITQEIPDPSRL 256
Query: 212 P--ASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTG 269
P ASW + F T F F+ V + + ++ H+ + L + +Y
Sbjct: 257 PLVASWKTYPLFFGTAIFSFE--SIGVVLPLENKMKNARHFPAILSLGMSIVTSLYIGMA 314
Query: 270 VYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSC 329
G+L FG ++ A + ++ P N + ++L+ I+ Y + ++ ++
Sbjct: 315 ALGYLRFGDDIKASISLNLP-NCWLYQSVKLLYIAGILCTYALQFYVPAEIII------- 366
Query: 330 LGGWGPSALADPSGLW---VRMPLTILWVTVTLAMALFMPDLSEIVSIIGGIS-SFFIFI 385
P A++ S W + + + ++ V +T +A+ +P L ++S++G +S + I
Sbjct: 367 -----PFAISRVSTRWALPLDLSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALALI 421
Query: 386 FPGLCLICAM---GVEPIGPRVKCCLEVWGVVSVLVGTF 421
P L + G+ P+ + + G V +VGT+
Sbjct: 422 IPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTY 460
>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
sapiens]
Length = 511
Score = 55.8 bits (133), Expect = 7e-08
Identities = 90/447 (20%), Positives = 171/447 (38%), Gaps = 94/447 (21%)
Query: 13 EKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISG 72
E HPA A LS M + L+K +G GLL P A AG +V + + ++ +
Sbjct: 32 ENVHPAGEAG-LSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCM 90
Query: 73 LVILGYAAAVS----------GQATYQGV------------------------------V 92
+++L A +S G+AT G+ +
Sbjct: 91 VILLNCAQHLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRWNLALSPRLECSGKI 150
Query: 93 RGLCGPAI----GKLCEACFLLNLLMISVAFLRVI-------------GDQLEKLCDS-- 133
C P + +A + + +V+FL VI D L+++ +
Sbjct: 151 SAHCNPHLQGSSNSPAQASRVAGIYRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAH 210
Query: 134 ----------LLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLA 183
+L+ TP +Y LP L +LV I K S+ TLA
Sbjct: 211 VTSNICQPREILTLTPILDIRFY--MLIILPFLILLVF--------IQNLKVLSVFSTLA 260
Query: 184 ACYLALVITVQYYLWPQGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYCSMR 243
+ + + +G+ S+ L A+W + F T F F+ + + M+
Sbjct: 261 NITTLGSMALIFEYIMEGIPYPSNLPLM-ANWKTFLLFFGTAIFTFEGVGMVLPLKNQMK 319
Query: 244 KRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFA 303
++ V L + ++Y L G G++ FG++ A + ++ P N + +++++
Sbjct: 320 HPQ--QFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLP-NCWLYQSVKLMYS 376
Query: 304 VSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMAL 363
+ I Y + + ++ F S +++ L+V + + V +T A+
Sbjct: 377 IGIFFTYALQFHVPAEIIIPF---------AISQVSESWALFVDLSVRSALVCLTCVSAI 427
Query: 364 FMPDLSEIVSIIGGISSFFI-FIFPGL 389
+P L ++S++G +SS + I P L
Sbjct: 428 LIPRLDLVISLVGSVSSSALALIIPAL 454
>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
Length = 476
Score = 55.8 bits (133), Expect = 7e-08
Identities = 79/416 (18%), Positives = 162/416 (38%), Gaps = 45/416 (10%)
Query: 33 LMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFL-ISGLVI---------LGYAAAV 82
L+K +G GLL P A AG V+ + ++ +V + G+++ L +
Sbjct: 56 LLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVD 115
Query: 83 SGQATYQGVVRGLCGPAIG------KLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLS 136
G G+ C ++ + ++ L + + D +++ ++
Sbjct: 116 YGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANG 175
Query: 137 GTPPAPQ-------PWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLAL 189
T P + + L L LV+L I + SI LA + +
Sbjct: 176 TTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVF-----IRNLRALSIFSLLANITMLV 230
Query: 190 VITVQYYLWPQGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSH 249
+ + Y Q + SH L A W + F T F F+ + + M+
Sbjct: 231 SLVMIYQFIVQRIPDPSHLPLV-APWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPR--K 287
Query: 250 WALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTV 309
+ L+ L ++ ++Y G G+L FG + + ++ P N + ++L+++ I
Sbjct: 288 FPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLP-NCWLYQSVKLLYSIGIFFT 346
Query: 310 YPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDLS 369
Y + ++ ++ F+ S + L V + + + V +T +A+ +P L
Sbjct: 347 YALQFYVPAEIIIPFF---------VSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLD 397
Query: 370 EIVSIIGGISSFFI-FIFPGLCLICAM---GVEPIGPRVKCCLEVWGVVSVLVGTF 421
++S++G +SS + I P L + G+ P+ + + G V +VGT+
Sbjct: 398 LVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTY 453
>gi|222418629 solute carrier family 38, member 9 [Homo sapiens]
Length = 561
Score = 55.5 bits (132), Expect = 1e-07
Identities = 87/431 (20%), Positives = 164/431 (38%), Gaps = 72/431 (16%)
Query: 25 SSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAAAVSG 84
+S+ +F++ + +G +L+ PW +AG ++ L+ L+ L ++ +
Sbjct: 118 TSLVTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLYCCYRVVKSRTMMFS 177
Query: 85 QATYQGVVRGLCGPAIGKLCE----------------------ACFLLNLLMISVAFLRV 122
T +C G + + FL N F+
Sbjct: 178 LDTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLFNTGKFIFNFIHH 237
Query: 123 IGD---------QLEKLCDSLLSGTPP--APQPWYA------------DQRFTLPLLSVL 159
I D +C S SG P + +YA D+ T+P V
Sbjct: 238 INDTDTILSTNNSNPVICPSAGSGGHPDNSSMIFYANDTGAQQFEKWWDKSRTVPFYLVG 297
Query: 160 VILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRESHPSLSPASWT-SV 218
++LPL + +F +ILGT++ YL ++T + G E H + + +
Sbjct: 298 LLLPLLNFKSPSFFSKFNILGTVSVLYLIFLVTFKAVRL--GFHLEFHWFIPTEFFVPEI 355
Query: 219 FSVFP----TICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFL 274
FP + F H +++ + +K+ + L L+ L Y GV F
Sbjct: 356 RFQFPQLTGVLTLAFFIHNCIITLLKNNKKQENNVRDLCIAYMLVT--LTYLYIGVLVFA 413
Query: 275 TFGTE------VSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRS 328
+F + + + L ++P +D + +AR+ ++TVYP++ +L R +
Sbjct: 414 SFPSPPLSKDCIEQNFLDNFPSSDTLSFIARIFLLFQMMTVYPLLGYLARVQLLG----H 469
Query: 329 CLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGISSF-FIFIFP 387
G PS ++ + L ++ V + MA F P++ I+ G F+FI+P
Sbjct: 470 IFGDIYPS-------IFHVLILNLIIVGAGVIMACFYPNIGGIIRYSGAACGLAFVFIYP 522
Query: 388 GLCLICAMGVE 398
L I ++ E
Sbjct: 523 SLIYIISLHQE 533
>gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
Length = 525
Score = 48.9 bits (115), Expect = 9e-06
Identities = 73/372 (19%), Positives = 149/372 (40%), Gaps = 48/372 (12%)
Query: 39 GAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILG--YAAAVSGQA-----TYQGV 91
G +L P+A GG + FL+ ++V +G +++ Y G+ +Y +
Sbjct: 131 GMFVLGLPYAILH-GGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSYVAI 189
Query: 92 VRGLCGPAI----GKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWYA 147
C P G++ ++ L+M + ++ V G+ L + G P + + W
Sbjct: 190 ANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGN----LMYNSFPGLPVSQKSW-- 243
Query: 148 DQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRESH 207
+++ V+LP + + + S+L TLA ++ ++ + Y L R
Sbjct: 244 ------SIIATAVLLPCAFLKNLKAVSKFSLLCTLAH-FVINILVIAYCL-----SRARD 291
Query: 208 PSLSPASWTSVFSVFPT----ICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCL 263
+ + FP I F + S+ +M++ S H + + +A C+
Sbjct: 292 WAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMN--WTHIAACV 349
Query: 264 IYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLF-----LGR 318
+ L + +LT+ E + + PG+ + V + + YP+ F L +
Sbjct: 350 LKGLFALVAYLTWADETKEVITDNLPGS--IRAVVNIFLVAKALLSYPLPFFAAVEVLEK 407
Query: 319 SVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGI 378
S+ Q+ R + GL +R L V TL MA+++P + ++ + G +
Sbjct: 408 SLFQEGSRAFFPACYSGDGRLKSWGLTLRCAL----VVFTLLMAIYVPHFALLMGLTGSL 463
Query: 379 S-SFFIFIFPGL 389
+ + F+ P L
Sbjct: 464 TGAGLCFLLPSL 475
>gi|21389443 transmembrane protein 125 [Homo sapiens]
Length = 219
Score = 33.5 bits (75), Expect = 0.39
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 20/128 (15%)
Query: 20 AAATLSSMGAVFILMKSALGAGLLNFPW-------AFSKAGGVVPAFLVELVSLVFLISG 72
A T+ + A+ +L+K + + + + A ++GG A +V L LV L++G
Sbjct: 69 ATGTVLCLLALLVLVKQLMSSAVQDMNCIRQAHHVALLRSGGGADALVVLLSGLVLLVTG 128
Query: 73 LVILGYAAAVSGQATYQGVVR-GLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLC 131
L + G AAA + ++ G+ A+G L LL LL+ V + C
Sbjct: 129 LTLAGLAAAPAPARPLAAMLSVGIALAALGSL----LLLGLLLYQVG--------VSGHC 176
Query: 132 DSLLSGTP 139
S+ TP
Sbjct: 177 PSICMATP 184
>gi|23592222 olfactory receptor, family 5, subfamily P, member 2
[Homo sapiens]
Length = 322
Score = 32.7 bits (73), Expect = 0.66
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 7/121 (5%)
Query: 206 SHPSLSPASWTSVFSVFPTICFGFQCHEAAVS-IYCSMRKRSLSHWALVSVLSLLACCLI 264
SH + + +++S SV P + F VS + C+++ S + +A V + LLA
Sbjct: 60 SHLAFADMAYSS--SVTPNMLVNFLVERNTVSYLGCAIQLGSAAFFATVECV-LLAAMAY 116
Query: 265 YSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDF 324
+ L + T++S V + +V+ +A L AVS T + +LF G + + F
Sbjct: 117 DRFVAICSPLLYSTKMSTQVSVQLL---LVVYIAGFLIAVSYTTSFYFLLFCGPNQVNHF 173
Query: 325 W 325
+
Sbjct: 174 F 174
>gi|31542943 solute carrier family 35, member F2 [Homo sapiens]
Length = 374
Score = 32.0 bits (71), Expect = 1.1
Identities = 42/165 (25%), Positives = 66/165 (40%), Gaps = 40/165 (24%)
Query: 274 LTFGTEVSADVLMSYPGN--------DMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFW 325
L GT V AD+L N D+++++ L+A+S V IV L R Q+F
Sbjct: 173 LGVGTMVGADILAGREDNSGSDVLIGDILVLLGASLYAISNVCEEYIVKKLSR---QEF- 228
Query: 326 RRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGISSFFIFI 385
LG G L+ T+ + L + + +I SI +F+
Sbjct: 229 ----LGMVG------------------LFGTIISGIQLLIVEYKDIASIHWDWKIALLFV 266
Query: 386 FPGLCLICAMGVEPIGPRVKCCLEV-WGVV-----SVLVGTFIFG 424
LC+ C P+ +V V G++ S+ VG F+FG
Sbjct: 267 AFALCMFCLYSFMPLVIKVTSATSVNLGILTADLYSLFVGLFLFG 311
>gi|186910319 solute carrier family 12, member 3 isoform 3 [Homo
sapiens]
Length = 1021
Score = 30.4 bits (67), Expect = 3.3
Identities = 33/134 (24%), Positives = 54/134 (40%), Gaps = 6/134 (4%)
Query: 2 EGQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGL-LNFPWAFSKAGGVVPAFL 60
+G G G + +P G + M + G L L PW ++AG V+ +
Sbjct: 115 DGLVEGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWII 174
Query: 61 VELVSLVFLISGLVI--LGYAAAVSGQATYQGVVRGL---CGPAIGKLCEACFLLNLLMI 115
+ L V I+GL I + V TY + R L G +IG + + + M
Sbjct: 175 ILLSVTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMH 234
Query: 116 SVAFLRVIGDQLEK 129
+V F + D L++
Sbjct: 235 TVGFAETVRDLLQE 248
>gi|186910317 solute carrier family 12, member 3 isoform 2 [Homo
sapiens]
Length = 1029
Score = 30.4 bits (67), Expect = 3.3
Identities = 33/134 (24%), Positives = 54/134 (40%), Gaps = 6/134 (4%)
Query: 2 EGQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGL-LNFPWAFSKAGGVVPAFL 60
+G G G + +P G + M + G L L PW ++AG V+ +
Sbjct: 114 DGLVEGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWII 173
Query: 61 VELVSLVFLISGLVI--LGYAAAVSGQATYQGVVRGL---CGPAIGKLCEACFLLNLLMI 115
+ L V I+GL I + V TY + R L G +IG + + + M
Sbjct: 174 ILLSVTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMH 233
Query: 116 SVAFLRVIGDQLEK 129
+V F + D L++
Sbjct: 234 TVGFAETVRDLLQE 247
>gi|186910315 solute carrier family 12, member 3 isoform 1 [Homo
sapiens]
Length = 1030
Score = 30.4 bits (67), Expect = 3.3
Identities = 33/134 (24%), Positives = 54/134 (40%), Gaps = 6/134 (4%)
Query: 2 EGQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGL-LNFPWAFSKAGGVVPAFL 60
+G G G + +P G + M + G L L PW ++AG V+ +
Sbjct: 115 DGLVEGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWII 174
Query: 61 VELVSLVFLISGLVI--LGYAAAVSGQATYQGVVRGL---CGPAIGKLCEACFLLNLLMI 115
+ L V I+GL I + V TY + R L G +IG + + + M
Sbjct: 175 ILLSVTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMH 234
Query: 116 SVAFLRVIGDQLEK 129
+V F + D L++
Sbjct: 235 TVGFAETVRDLLQE 248
>gi|197927133 hypothetical protein LOC84970 isoform a [Homo sapiens]
Length = 598
Score = 29.3 bits (64), Expect = 7.3
Identities = 12/38 (31%), Positives = 22/38 (57%), Gaps = 3/38 (7%)
Query: 125 DQLEKLCDSL---LSGTPPAPQPWYADQRFTLPLLSVL 159
D L+K C + + G P A QPW + ++ ++P++ L
Sbjct: 60 DSLDKTCHEIWKRVQGLPEASQPWTSMEQLSVPVVGTL 97
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.141 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,383,742
Number of Sequences: 37866
Number of extensions: 701618
Number of successful extensions: 2378
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2321
Number of HSP's gapped (non-prelim): 37
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.