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Search of human proteins with 122937269
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]
(430 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens] 904 0.0
gi|7657307 LIM domains containing 1 [Homo sapiens] 384 e-107
gi|14249622 ajuba isoform 1 [Homo sapiens] 349 2e-96
gi|5031887 LIM domain containing preferred translocation partner... 243 3e-64
gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens] 223 3e-58
gi|58530845 zyxin [Homo sapiens] 202 5e-52
gi|4508047 zyxin [Homo sapiens] 202 5e-52
gi|37675280 ajuba isoform 2 [Homo sapiens] 192 6e-49
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens] 173 2e-43
gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens] 166 4e-41
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens] 107 2e-23
gi|109638745 transforming growth factor beta 1 induced transcrip... 91 2e-18
gi|21361591 transforming growth factor beta 1 induced transcript... 91 2e-18
gi|170932518 paxillin isoform 3 [Homo sapiens] 90 4e-18
gi|170932516 paxillin isoform 2 [Homo sapiens] 90 4e-18
gi|170932514 paxillin isoform 1 [Homo sapiens] 90 4e-18
gi|221316659 leupaxin isoform 1 [Homo sapiens] 89 6e-18
gi|4758670 leupaxin isoform 2 [Homo sapiens] 89 6e-18
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 88 1e-17
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 88 1e-17
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 88 1e-17
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 88 1e-17
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 88 1e-17
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 88 1e-17
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 86 6e-17
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 86 6e-17
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens] 86 6e-17
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 84 2e-16
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 84 2e-16
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 84 2e-16
>gi|122937269 Wilms tumor 1 interacting protein [Homo sapiens]
Length = 430
Score = 904 bits (2337), Expect = 0.0
Identities = 430/430 (100%), Positives = 430/430 (100%)
Query: 1 MQRSRAGADEAALLLAGLALRELEPGCGSPGRGRRGPRPGPGDEAAPALGRRGKGSGGPE 60
MQRSRAGADEAALLLAGLALRELEPGCGSPGRGRRGPRPGPGDEAAPALGRRGKGSGGPE
Sbjct: 1 MQRSRAGADEAALLLAGLALRELEPGCGSPGRGRRGPRPGPGDEAAPALGRRGKGSGGPE 60
Query: 61 AGADGLSRGERGPRRAAVPELSAQPAGSPRASLAGSDGGGGGGSARSSGISLGYDQRHGS 120
AGADGLSRGERGPRRAAVPELSAQPAGSPRASLAGSDGGGGGGSARSSGISLGYDQRHGS
Sbjct: 61 AGADGLSRGERGPRRAAVPELSAQPAGSPRASLAGSDGGGGGGSARSSGISLGYDQRHGS 120
Query: 121 PRSGRSDPRPGPGPPSVGSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEPAGPAPF 180
PRSGRSDPRPGPGPPSVGSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEPAGPAPF
Sbjct: 121 PRSGRSDPRPGPGPPSVGSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEPAGPAPF 180
Query: 181 PLPALPLPPGREGGPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQACQ 240
PLPALPLPPGREGGPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQACQ
Sbjct: 181 PLPALPLPPGREGGPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQACQ 240
Query: 241 AMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEM 300
AMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEM
Sbjct: 241 AMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEM 300
Query: 301 ILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPA 360
ILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPA
Sbjct: 301 ILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPA 360
Query: 361 QGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRRCHLRRLQPGPL 420
QGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRRCHLRRLQPGPL
Sbjct: 361 QGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRRCHLRRLQPGPL 420
Query: 421 PSPTVHVTEL 430
PSPTVHVTEL
Sbjct: 421 PSPTVHVTEL 430
>gi|7657307 LIM domains containing 1 [Homo sapiens]
Length = 676
Score = 384 bits (987), Expect = e-107
Identities = 202/413 (48%), Positives = 246/413 (59%), Gaps = 29/413 (7%)
Query: 21 RELEPGCGSPGRGRRGPRPGPGDEAAPA--------------LGRRGKGSGGPEAGADGL 66
+ + PG SP P GP P+ L R G GG +G +
Sbjct: 269 QRVSPGLPSPNLENGAPAVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGV--M 326
Query: 67 SRGERGPRRAAVPELSAQPAGSPRASLAGSDGGGGGGSARSSGISLGYDQRHGSPRSGRS 126
S+ P+ P P +S S G GS + + LG P+ G +
Sbjct: 327 SKPNVDPQ----PWFQDGPKSYLSSSAPSSSPAGLDGSQQGAVPGLG-------PKPGCT 375
Query: 127 DPRPGPGPPSVGSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEPAGPAPFPLPALP 186
D GP +S+L + G+ + P+ P LP P
Sbjct: 376 DLGTGPKLSPTSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLD-SPSSPR-VRLPCQP 433
Query: 187 LPPGREGGPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQACQAMGSLY 246
L PG E PSAAE +LEALT+ LER ++A DYFG C+KC G++GA QACQAMG+LY
Sbjct: 434 LVPGPELRPSAAELKLEALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLY 493
Query: 247 HTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALG 306
H CFTC +C R+LRGKAFY V KV+C+EDFLYSGFQQ+AD+C +CGHLIM+MILQALG
Sbjct: 494 HDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALG 553
Query: 307 KSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETT 366
KSYHPGCFRC +CNECLDGVPFTVD EN IYCVRDYH V APKCA+C PILP +G + T
Sbjct: 554 KSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDET 613
Query: 367 IRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRRCHLRRLQPGP 419
IRVVSMDRDYHV CYHCEDCGL+L+ E+G RCYPL HL C CH++RL+ P
Sbjct: 614 IRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKRP 666
>gi|14249622 ajuba isoform 1 [Homo sapiens]
Length = 538
Score = 349 bits (896), Expect = 2e-96
Identities = 217/498 (43%), Positives = 252/498 (50%), Gaps = 103/498 (20%)
Query: 26 GCGSPGR-GRRGPRPGPGDEAAPALGRRGKGSGGPEAGADGLSRGER-------GP---R 74
G G P + G RG GPGDE P R +GS E G R GP R
Sbjct: 40 GLGGPRKSGPRGATGGPGDE--PLEPAREQGSLDAERNQRGSFEAPRYEGSFPAGPPPTR 97
Query: 75 RAAVPEL--------SAQPAGSPRASLAGS-----------------DGGGGGG------ 103
+P+ PA SPR+S A S DG G GG
Sbjct: 98 ALPLPQSLPPDFRLEPTAPALSPRSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRP 157
Query: 104 -SARSSGISLGYDQRHGS-----------PRSGRSDPRPGPGPPSV-------------- 137
S R+SGIS+GYDQRHGS P +G G PS
Sbjct: 158 CSNRTSGISMGYDQRHGSPLPAGPCLFGPPLAGAPAGYSPGGVPSAYPELHAALDRLYAQ 217
Query: 138 -----GSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEP-----------AGPAPFP 181
G S S + GS GA A A P R +P A A +
Sbjct: 218 RPAGFGCQESRHSYPPALGSPGALAGAGVGAAGPLERRGAQPGRHSVTGYGDCAVGARYQ 277
Query: 182 LPALPL------PPGREGG---------PSAAERRLEALTRELERAL--EARTARDYFGI 224
L GRE G PS E E RA E DYFG
Sbjct: 278 DELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPGPFVPEAARARMREPEAREDYFGT 337
Query: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284
CIKC GIYG ACQA+ SLYHT CF C SCGR LR KAFY+V VYC+ED+L+SGFQ
Sbjct: 338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQ 397
Query: 285 QTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHT 344
+ A+KC VCGHLI+E ILQA+GKSYHPGCFRC VCN+CLDG+PFTVD N +YCV DYH
Sbjct: 398 EAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHK 457
Query: 345 VFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGH 404
+APKCA+C +PILP++GCE +RV+SMDRDYH CYHCEDC +QLS EEG C+PL GH
Sbjct: 458 NYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGH 517
Query: 405 LLCRRCHLRRLQPGPLPS 422
LLC CH++RL P+
Sbjct: 518 LLCHGCHMQRLNARQPPA 535
Score = 36.6 bits (83), Expect = 0.045
Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 17/98 (17%)
Query: 91 ASLAGSDGGGGGGSARSSGISLGYDQRHGSPRSGRSDPRPGPGPPSVGSARSSVSSLGSR 150
+S +GSDG G G R SG+ G +SG GPG + AR S R
Sbjct: 22 SSRSGSDGTPGPGKGRLSGLG-------GPRKSGPRGATGGPGDEPLEPAREQGSLDAER 74
Query: 151 GSAGAYADFLPPGACPAPARSPEPAGPAPFPLPALPLP 188
G++ G+ PA P P ALPLP
Sbjct: 75 NQRGSFEAPRYEGSFPA----------GPPPTRALPLP 102
>gi|5031887 LIM domain containing preferred translocation partner in
lipoma [Homo sapiens]
Length = 612
Score = 243 bits (619), Expect = 3e-64
Identities = 127/320 (39%), Positives = 174/320 (54%), Gaps = 30/320 (9%)
Query: 120 SPRSGRSDPRPGPGPPSVGSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEPAGPAP 179
+P GR P G S + G +G + PG P A + P G P
Sbjct: 290 APNQGRYYEGYYAAGPGYGGRNDSDPTYGQQGHPNTWKR--EPGYTPPGAGNQNPPGMYP 347
Query: 180 FPLP-------------ALPLPP--GREG--GPSAA------ERRLEALTRELERALEAR 216
P A PL P G G GPS+ E LE LT+++ +E
Sbjct: 348 VTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPSSVAPSFRPEDELEHLTKKMLYDMENP 407
Query: 217 TARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQE 276
A +YFG C +CG + G C AM ++H DCFTC C +LRG+ FY V +K YC+
Sbjct: 408 PADEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEP 467
Query: 277 DFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNI 336
++ T ++C+VC IME IL+A GK+YHP CF C +C+ LDG+PFTVD I
Sbjct: 468 CYI-----NTLEQCNVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLI 522
Query: 337 YCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGR 396
+C+ D+H FAP+C+ C PI+PA G E T+R+V++DRD+HV CY CEDCG LS + +
Sbjct: 523 HCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQ 582
Query: 397 RCYPLAGHLLCRRCHLRRLQ 416
CYPL GH+LC+ C+ R++
Sbjct: 583 GCYPLDGHILCKTCNSARIR 602
>gi|91208423 thyroid receptor-interacting protein 6 [Homo sapiens]
Length = 476
Score = 223 bits (567), Expect = 3e-58
Identities = 142/407 (34%), Positives = 194/407 (47%), Gaps = 49/407 (12%)
Query: 34 RRGPRPGPGDEAAPAL--------GRRGKGSGGPEAGA------DGLSRGERGPRRAAVP 79
R G RPG D L G RG S P+ A G P A+
Sbjct: 85 RGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRPDRQAYEPPPPPAYRTGSLKPNPAS-- 142
Query: 80 ELSAQPAGSPRASLAGSDGGGGGGSARSSGISLGYDQRH-GSPRSGRSD---PRPGPGPP 135
L A P G P + + + G A + + R G PR G S P PGP P
Sbjct: 143 PLPASPYGGPTPA-SYTTASTPAGPAFPVQVKVAQPVRGCGPPRRGASQASGPLPGPHFP 201
Query: 136 SVGSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEPAGPAPFPLPALPLPPGREGGP 195
G S+ G PGA A PAG G E GP
Sbjct: 202 LPGRGEVWGPGYRSQREPG-------PGAKEEAAGVSGPAGRGR----------GGEHGP 244
Query: 196 SAA-----ERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQACQAMGSLYHTDC 250
E L+ LT++L + + +YFG C CG + G A+ ++H C
Sbjct: 245 QVPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGC 304
Query: 251 FTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYH 310
F C +C +LRG+ FY V + YC+ ++ T +KC+ C I++ IL+A+GK+YH
Sbjct: 305 FVCSTCRAQLRGQHFYAVERRAYCEGCYV-----ATLEKCATCSQPILDRILRAMGKAYH 359
Query: 311 PGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVV 370
PGCF C VC+ LDG+PFTVD + I+C+ D+H FAP+C+ C I+P G E T+R+V
Sbjct: 360 PGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIV 419
Query: 371 SMDRDYHVACYHCEDCGLQLSGE-EGRRCYPLAGHLLCRRCHLRRLQ 416
++DR +H+ CY CE+CGL LS E E + CYPL GH+LC+ C R+Q
Sbjct: 420 ALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQ 466
Score = 31.2 bits (69), Expect = 1.9
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 4/81 (4%)
Query: 25 PGCGS---PG-RGRRGPRPGPGDEAAPALGRRGKGSGGPEAGADGLSRGERGPRRAAVPE 80
PG G PG R +R P PG +EAA G G+G GG LS+ +
Sbjct: 203 PGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGGEHGPQVPLSQPPEDELDRLTKK 262
Query: 81 LSAQPAGSPRASLAGSDGGGG 101
L P G GG G
Sbjct: 263 LVHDMNHPPSGEYFGQCGGCG 283
>gi|58530845 zyxin [Homo sapiens]
Length = 572
Score = 202 bits (514), Expect = 5e-52
Identities = 119/338 (35%), Positives = 176/338 (52%), Gaps = 32/338 (9%)
Query: 105 ARSSGISLGYDQRHGSPRSGRSD-PRPGPGPPSVGSARSSVSSLGSRGSAGAYAD--FLP 161
+++ +SL Q G P S + P+ P P S S G+ G +G+ +
Sbjct: 240 SQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSP-GAPGGSGSQPNQKLGH 298
Query: 162 PGACPAPARSPEPAG---------------PAPFPLPALPL----PPGREGGPSAAE-RR 201
P A A SP+P P P PA PG G + E
Sbjct: 299 PEALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEE 358
Query: 202 LEALTRELERALEARTARDYF--GICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRR 259
LE LT++L + +E ++ +C +C + AQ A +A+G L+H CFTC C ++
Sbjct: 359 LEQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQ 418
Query: 260 LRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVC 319
L+G+ FY++ YC+ + T +KC+ CG I + +L+A GK+YHP CF C VC
Sbjct: 419 LQGQQFYSLEGAPYCE-----GCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVC 473
Query: 320 NECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVA 379
L+G F VD N +CV DYH +AP+C+ C+ PI+P G + T+RVV++D+++H+
Sbjct: 474 ARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMK 533
Query: 380 CYHCEDCGLQLSGE-EGRRCYPLAGHLLCRRCHLRRLQ 416
CY CEDCG LS E + C+PL GH+LCR+CH R Q
Sbjct: 534 CYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARAQ 571
Score = 32.0 bits (71), Expect = 1.1
Identities = 23/68 (33%), Positives = 26/68 (38%), Gaps = 10/68 (14%)
Query: 130 PGPGPPSVGSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEPAGPAPFPLPALPLPP 189
P P PP G + +LG F PP + P P FP P P PP
Sbjct: 72 PLPPPPLAGDGDDAEGALGGA--------FPPPPPPIEESFPPAPLEEEIFPSP--PPPP 121
Query: 190 GREGGPSA 197
EGGP A
Sbjct: 122 EEEGGPEA 129
>gi|4508047 zyxin [Homo sapiens]
Length = 572
Score = 202 bits (514), Expect = 5e-52
Identities = 119/338 (35%), Positives = 176/338 (52%), Gaps = 32/338 (9%)
Query: 105 ARSSGISLGYDQRHGSPRSGRSD-PRPGPGPPSVGSARSSVSSLGSRGSAGAYAD--FLP 161
+++ +SL Q G P S + P+ P P S S G+ G +G+ +
Sbjct: 240 SQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSP-GAPGGSGSQPNQKLGH 298
Query: 162 PGACPAPARSPEPAG---------------PAPFPLPALPL----PPGREGGPSAAE-RR 201
P A A SP+P P P PA PG G + E
Sbjct: 299 PEALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEE 358
Query: 202 LEALTRELERALEARTARDYF--GICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRR 259
LE LT++L + +E ++ +C +C + AQ A +A+G L+H CFTC C ++
Sbjct: 359 LEQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQ 418
Query: 260 LRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVC 319
L+G+ FY++ YC+ + T +KC+ CG I + +L+A GK+YHP CF C VC
Sbjct: 419 LQGQQFYSLEGAPYCE-----GCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVC 473
Query: 320 NECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVA 379
L+G F VD N +CV DYH +AP+C+ C+ PI+P G + T+RVV++D+++H+
Sbjct: 474 ARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMK 533
Query: 380 CYHCEDCGLQLSGE-EGRRCYPLAGHLLCRRCHLRRLQ 416
CY CEDCG LS E + C+PL GH+LCR+CH R Q
Sbjct: 534 CYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARAQ 571
Score = 32.0 bits (71), Expect = 1.1
Identities = 23/68 (33%), Positives = 26/68 (38%), Gaps = 10/68 (14%)
Query: 130 PGPGPPSVGSARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEPAGPAPFPLPALPLPP 189
P P PP G + +LG F PP + P P FP P P PP
Sbjct: 72 PLPPPPLAGDGDDAEGALGGA--------FPPPPPPIEESFPPAPLEEEIFPSP--PPPP 121
Query: 190 GREGGPSA 197
EGGP A
Sbjct: 122 EEEGGPEA 129
>gi|37675280 ajuba isoform 2 [Homo sapiens]
Length = 121
Score = 192 bits (487), Expect = 6e-49
Identities = 78/118 (66%), Positives = 94/118 (79%)
Query: 305 LGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCE 364
+GKSYHPGCFRC VCN+CLDG+PFTVD N +YCV DYH +APKCA+C +PILP++GCE
Sbjct: 1 MGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCE 60
Query: 365 TTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRRCHLRRLQPGPLPS 422
+RV+SMDRDYH CYHCEDC +QLS EEG C+PL GHLLC CH++RL P+
Sbjct: 61 DIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLNARQPPA 118
>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
Length = 373
Score = 173 bits (439), Expect = 2e-43
Identities = 94/279 (33%), Positives = 136/279 (48%), Gaps = 27/279 (9%)
Query: 158 DFLPPGACPAPARSP-EPAGPAPFPL------------PALPLPPGREGGPSAAERRLEA 204
D LPP P P P E PAP P P P GPS L
Sbjct: 102 DLLPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRP 161
Query: 205 LTRELE----RALEARTARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRL 260
+ EL +E + D IC C + + A +AM YH CFTC +C R+L
Sbjct: 162 MEEELPPPPAEPVEKGASTD---ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQL 218
Query: 261 RGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCN 320
G++FY + C+ + Q T ++C CG ++ + I++ALG+++HP CF C C
Sbjct: 219 AGQSFYQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCA 273
Query: 321 ECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVAC 380
C+ F + +N +YC+ D++ FAP C+ C PI+P G + ++ M R++H C
Sbjct: 274 RCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDG-KDAFKIECMGRNFHENC 332
Query: 381 YHCEDCGLQLSGE-EGRRCYPLAGHLLCRRCHLRRLQPG 418
Y CEDC + LS E + CYPL HL C+ CH++R G
Sbjct: 333 YRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAG 371
>gi|66932988 filamin-binding LIM protein-1 isoform c [Homo sapiens]
Length = 276
Score = 166 bits (420), Expect = 4e-41
Identities = 89/258 (34%), Positives = 132/258 (51%), Gaps = 26/258 (10%)
Query: 162 PGACPAPARSPEPAGPAPFPLPALPLPPGREGGPSAAERRLEALTRELERALEARTARDY 221
P PAP ++PE AG A P P PGR A + A +L
Sbjct: 42 PWEAPAPMKTPE-AGLAGRPSPWTT--PGR------AAATVPAAPMQLFNG--------- 83
Query: 222 FGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYS 281
IC C + + A +AM YH CFTC +C R+L G++FY + C+ +
Sbjct: 84 -DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCY--- 139
Query: 282 GFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRD 341
Q T ++C CG ++ + I++ALG+++HP CF C C C+ F + +N +YC+ D
Sbjct: 140 --QDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDD 197
Query: 342 YHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGE-EGRRCYP 400
++ FAP C+ C PI+P G + ++ M R++H CY CEDC + LS E + CYP
Sbjct: 198 FYRKFAPVCSICENPIIPRDG-KDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYP 256
Query: 401 LAGHLLCRRCHLRRLQPG 418
L HL C+ CH++R G
Sbjct: 257 LNNHLFCKPCHVKRSAAG 274
>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
Length = 374
Score = 107 bits (268), Expect = 2e-23
Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 25/203 (12%)
Query: 158 DFLPPGACPAPARSP-EPAGPAPFPL------------PALPLPPGREGGPSAAERRLEA 204
D LPP P P P E PAP P P P GPS L
Sbjct: 102 DLLPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRP 161
Query: 205 LTRELE----RALEARTARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRL 260
+ EL +E + D IC C + + A +AM YH CFTC +C R+L
Sbjct: 162 MEEELPPPPAEPVEKGASTD---ICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQL 218
Query: 261 RGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCN 320
G++FY + C+ + Q T ++C CG ++ + I++ALG+++HP CF C C
Sbjct: 219 AGQSFYQKDGRPLCEPCY-----QDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCA 273
Query: 321 ECLDGVPFTVDVENNIYCVRDYH 343
C+ F + +N +YC+ D++
Sbjct: 274 RCIGDESFALGSQNEVYCLDDFY 296
Score = 40.0 bits (92), Expect = 0.004
Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 8/67 (11%)
Query: 350 CASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRR 409
CA C + + P + + V +M R YH C+ C C QL+G+ Y G LC
Sbjct: 183 CAFCHKTVSPRE-----LAVEAMKRQYHAQCFTCRTCRRQLAGQS---FYQKDGRPLCEP 234
Query: 410 CHLRRLQ 416
C+ L+
Sbjct: 235 CYQDTLE 241
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 91.3 bits (225), Expect = 2e-18
Identities = 100/397 (25%), Positives = 144/397 (36%), Gaps = 68/397 (17%)
Query: 30 PGRGRRGPRPGPGDEAAPALGRRGKGSGGPEAGADGLSRG-------ERGPRRAAVPELS 82
P G RP P+ G + + G +GA G R P+ AA
Sbjct: 19 PRSGAPKERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAA----- 73
Query: 83 AQPAGSPRASLAGSDGGGGGGSAR---------------------SSGISLGYDQRHGSP 121
PA P +S +G G G R SS ++ G + S
Sbjct: 74 --PAAPPFSSSSGVLGTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSE 131
Query: 122 RSGR----SDPRPGPGPPSVGSARSSVSSLGSRGSAGAYADFLPPGACPAP--ARSPEPA 175
R S P PG S SA + L + S + LP P S
Sbjct: 132 DKKRPSLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEG 191
Query: 176 GPAPFPLPALPLPPGREGGPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGA 235
P+P P P G+ + + L L +L R A+ G+C C I G
Sbjct: 192 SPSP------PEPTGK----GSLDTMLGLLQSDLSRRGVPTQAK---GLCGSCNKPIAG- 237
Query: 236 QQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGH 295
Q A+G +H + F C C L G +F+ +C E + F++ + +C C
Sbjct: 238 -QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECY----FERFSPRCGFCNQ 292
Query: 296 LIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCAR 355
I ++ ALG +HP F C C E F + E YC RD+ +FAP+C C
Sbjct: 293 PIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFH-EREGRPYCRRDFLQLFAPRCQGCQG 351
Query: 356 PILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSG 392
PIL + ++ +H C+ C +C SG
Sbjct: 352 PILDNY-------ISALSALWHPDCFVCRECFAPFSG 381
Score = 69.3 bits (168), Expect = 6e-12
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 17/174 (9%)
Query: 241 AMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEM 300
A+G+ +H + F C SCG + F+ + YC+ DFL Q A +C C I++
Sbjct: 301 ALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFL----QLFAPRCQGCQGPILDN 356
Query: 301 ILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPA 360
+ AL +HP CF C C G F + E C +H CA+C P+
Sbjct: 357 YISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGSLCATCGLPV--- 412
Query: 361 QGCETTIRVVSMDRDYHVACYHCEDCGLQLS-GEEGRRCYPLAGHLLCRRCHLR 413
T V ++ R +H + C C L+ G R AG C+ C L+
Sbjct: 413 ----TGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQER----AGKPYCQPCFLK 458
Score = 55.1 bits (131), Expect = 1e-07
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 11/133 (8%)
Query: 285 QTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHT 344
Q C C I ++ ALG+++HP F C C+ L G F + + +C Y
Sbjct: 223 QAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSF-FEKDGAPFCPECYFE 281
Query: 345 VFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGH 404
F+P+C C +PI V ++ +H + C CG + G+EG + G
Sbjct: 282 RFSPRCGFCNQPIRHKM-------VTALGTHWHPEHFCCVSCG-EPFGDEG--FHEREGR 331
Query: 405 LLCRRCHLRRLQP 417
CRR L+ P
Sbjct: 332 PYCRRDFLQLFAP 344
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 91.3 bits (225), Expect = 2e-18
Identities = 100/397 (25%), Positives = 144/397 (36%), Gaps = 68/397 (17%)
Query: 30 PGRGRRGPRPGPGDEAAPALGRRGKGSGGPEAGADGLSRG-------ERGPRRAAVPELS 82
P G RP P+ G + + G +GA G R P+ AA
Sbjct: 2 PRSGAPKERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAA----- 56
Query: 83 AQPAGSPRASLAGSDGGGGGGSAR---------------------SSGISLGYDQRHGSP 121
PA P +S +G G G R SS ++ G + S
Sbjct: 57 --PAAPPFSSSSGVLGTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSE 114
Query: 122 RSGR----SDPRPGPGPPSVGSARSSVSSLGSRGSAGAYADFLPPGACPAP--ARSPEPA 175
R S P PG S SA + L + S + LP P S
Sbjct: 115 DKKRPSLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEG 174
Query: 176 GPAPFPLPALPLPPGREGGPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGA 235
P+P P P G+ + + L L +L R A+ G+C C I G
Sbjct: 175 SPSP------PEPTGK----GSLDTMLGLLQSDLSRRGVPTQAK---GLCGSCNKPIAG- 220
Query: 236 QQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGH 295
Q A+G +H + F C C L G +F+ +C E + F++ + +C C
Sbjct: 221 -QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECY----FERFSPRCGFCNQ 275
Query: 296 LIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCAR 355
I ++ ALG +HP F C C E F + E YC RD+ +FAP+C C
Sbjct: 276 PIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFH-EREGRPYCRRDFLQLFAPRCQGCQG 334
Query: 356 PILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSG 392
PIL + ++ +H C+ C +C SG
Sbjct: 335 PILDNY-------ISALSALWHPDCFVCRECFAPFSG 364
Score = 69.3 bits (168), Expect = 6e-12
Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 17/174 (9%)
Query: 241 AMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEM 300
A+G+ +H + F C SCG + F+ + YC+ DFL Q A +C C I++
Sbjct: 284 ALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFL----QLFAPRCQGCQGPILDN 339
Query: 301 ILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPA 360
+ AL +HP CF C C G F + E C +H CA+C P+
Sbjct: 340 YISALSALWHPDCFVCRECFAPFSGGSF-FEHEGRPLCENHFHARRGSLCATCGLPV--- 395
Query: 361 QGCETTIRVVSMDRDYHVACYHCEDCGLQLS-GEEGRRCYPLAGHLLCRRCHLR 413
T V ++ R +H + C C L+ G R AG C+ C L+
Sbjct: 396 ----TGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQER----AGKPYCQPCFLK 441
Score = 55.1 bits (131), Expect = 1e-07
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 11/133 (8%)
Query: 285 QTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHT 344
Q C C I ++ ALG+++HP F C C+ L G F + + +C Y
Sbjct: 206 QAKGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSF-FEKDGAPFCPECYFE 264
Query: 345 VFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGH 404
F+P+C C +PI V ++ +H + C CG + G+EG + G
Sbjct: 265 RFSPRCGFCNQPIRHKM-------VTALGTHWHPEHFCCVSCG-EPFGDEG--FHEREGR 314
Query: 405 LLCRRCHLRRLQP 417
CRR L+ P
Sbjct: 315 PYCRRDFLQLFAP 327
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 89.7 bits (221), Expect = 4e-18
Identities = 56/200 (28%), Positives = 92/200 (46%), Gaps = 18/200 (9%)
Query: 188 PPGREGGP-SAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQACQAMGSLY 246
PPG P S + L +L +L + A A+ G+C C I G Q AMG +
Sbjct: 156 PPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAK---GVCGACKKPIAG--QVVTAMGKTW 210
Query: 247 HTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALG 306
H + F C C + + F+ + YC++D+ + +C C I++ ++ AL
Sbjct: 211 HPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY----HNLFSPRCYYCNGPILDKVVTALD 266
Query: 307 KSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETT 366
+++HP F C+ C F + + YC +DY +FAPKC CAR IL
Sbjct: 267 RTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFAPKCGGCARAILENY----- 320
Query: 367 IRVVSMDRDYHVACYHCEDC 386
+ +++ +H C+ C +C
Sbjct: 321 --ISALNTLWHPECFVCREC 338
Score = 70.9 bits (172), Expect = 2e-12
Identities = 45/155 (29%), Positives = 66/155 (42%), Gaps = 20/155 (12%)
Query: 241 AMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEM 300
A+ +H + F C CG + F+ K YC++D+ F A KC C I+E
Sbjct: 264 ALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDY----FDMFAPKCGGCARAILEN 319
Query: 301 ILQALGKSYHPGCFRCSVCNECLDGVPFT----VDVENNIYCVRDYHTVFAPKCASCARP 356
+ AL +HP CF VC EC PF + + YC YH C+ C +P
Sbjct: 320 YISALNTLWHPECF---VCRECF--TPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKP 374
Query: 357 ILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLS 391
I T + +M + +H + C C QL+
Sbjct: 375 I-------TGRCITAMAKKFHPEHFVCAFCLKQLN 402
Score = 66.2 bits (160), Expect = 5e-11
Identities = 39/128 (30%), Positives = 59/128 (46%), Gaps = 11/128 (8%)
Query: 290 CSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPK 349
C C I ++ A+GK++HP F C+ C E + F + + YC +DYH +F+P+
Sbjct: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNF-FERDGQPYCEKDYHNLFSPR 249
Query: 350 CASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRR 409
C C PIL V ++DR +H + C CG G EG + G CR+
Sbjct: 250 CYYCNGPILDKV-------VTALDRTWHPEHFFCAQCG-AFFGPEG--FHEKDGKAYCRK 299
Query: 410 CHLRRLQP 417
+ P
Sbjct: 300 DYFDMFAP 307
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/140 (25%), Positives = 62/140 (44%), Gaps = 9/140 (6%)
Query: 210 ERALEARTARDYFGICI-KCGLGIYGA--QQACQAMGSLYHTDCFTCDSCGRRLRGKAFY 266
E+ +A +DYF + KCG G A + A+ +L+H +CF C C +F+
Sbjct: 290 EKDGKAYCRKDYFDMFAPKCG-GCARAILENYISALNTLWHPECFVCRECFTPFVNGSFF 348
Query: 267 NVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGV 326
+ YC+ + ++ CS C I + A+ K +HP F C+ C + L+
Sbjct: 349 EHDGQPYCEVHY----HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404
Query: 327 PFTVDVENNIYCVRDYHTVF 346
F + + YC + +F
Sbjct: 405 TFK-EQNDKPYCQNCFLKLF 423
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 89.7 bits (221), Expect = 4e-18
Identities = 56/200 (28%), Positives = 92/200 (46%), Gaps = 18/200 (9%)
Query: 188 PPGREGGP-SAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQACQAMGSLY 246
PPG P S + L +L +L + A A+ G+C C I G Q AMG +
Sbjct: 289 PPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAK---GVCGACKKPIAG--QVVTAMGKTW 343
Query: 247 HTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALG 306
H + F C C + + F+ + YC++D+ + +C C I++ ++ AL
Sbjct: 344 HPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY----HNLFSPRCYYCNGPILDKVVTALD 399
Query: 307 KSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETT 366
+++HP F C+ C F + + YC +DY +FAPKC CAR IL
Sbjct: 400 RTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFAPKCGGCARAILENY----- 453
Query: 367 IRVVSMDRDYHVACYHCEDC 386
+ +++ +H C+ C +C
Sbjct: 454 --ISALNTLWHPECFVCREC 471
Score = 70.9 bits (172), Expect = 2e-12
Identities = 45/155 (29%), Positives = 66/155 (42%), Gaps = 20/155 (12%)
Query: 241 AMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEM 300
A+ +H + F C CG + F+ K YC++D+ F A KC C I+E
Sbjct: 397 ALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDY----FDMFAPKCGGCARAILEN 452
Query: 301 ILQALGKSYHPGCFRCSVCNECLDGVPFT----VDVENNIYCVRDYHTVFAPKCASCARP 356
+ AL +HP CF VC EC PF + + YC YH C+ C +P
Sbjct: 453 YISALNTLWHPECF---VCRECF--TPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKP 507
Query: 357 ILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLS 391
I T + +M + +H + C C QL+
Sbjct: 508 I-------TGRCITAMAKKFHPEHFVCAFCLKQLN 535
Score = 66.2 bits (160), Expect = 5e-11
Identities = 39/128 (30%), Positives = 59/128 (46%), Gaps = 11/128 (8%)
Query: 290 CSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPK 349
C C I ++ A+GK++HP F C+ C E + F + + YC +DYH +F+P+
Sbjct: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNF-FERDGQPYCEKDYHNLFSPR 382
Query: 350 CASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRR 409
C C PIL V ++DR +H + C CG G EG + G CR+
Sbjct: 383 CYYCNGPILDKV-------VTALDRTWHPEHFFCAQCG-AFFGPEG--FHEKDGKAYCRK 432
Query: 410 CHLRRLQP 417
+ P
Sbjct: 433 DYFDMFAP 440
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/140 (25%), Positives = 62/140 (44%), Gaps = 9/140 (6%)
Query: 210 ERALEARTARDYFGICI-KCGLGIYGA--QQACQAMGSLYHTDCFTCDSCGRRLRGKAFY 266
E+ +A +DYF + KCG G A + A+ +L+H +CF C C +F+
Sbjct: 423 EKDGKAYCRKDYFDMFAPKCG-GCARAILENYISALNTLWHPECFVCRECFTPFVNGSFF 481
Query: 267 NVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGV 326
+ YC+ + ++ CS C I + A+ K +HP F C+ C + L+
Sbjct: 482 EHDGQPYCEVHY----HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537
Query: 327 PFTVDVENNIYCVRDYHTVF 346
F + + YC + +F
Sbjct: 538 TFK-EQNDKPYCQNCFLKLF 556
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 89.7 bits (221), Expect = 4e-18
Identities = 56/200 (28%), Positives = 92/200 (46%), Gaps = 18/200 (9%)
Query: 188 PPGREGGP-SAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQACQAMGSLY 246
PPG P S + L +L +L + A A+ G+C C I G Q AMG +
Sbjct: 323 PPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAK---GVCGACKKPIAG--QVVTAMGKTW 377
Query: 247 HTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALG 306
H + F C C + + F+ + YC++D+ + +C C I++ ++ AL
Sbjct: 378 HPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY----HNLFSPRCYYCNGPILDKVVTALD 433
Query: 307 KSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETT 366
+++HP F C+ C F + + YC +DY +FAPKC CAR IL
Sbjct: 434 RTWHPEHFFCAQCGAFFGPEGFH-EKDGKAYCRKDYFDMFAPKCGGCARAILENY----- 487
Query: 367 IRVVSMDRDYHVACYHCEDC 386
+ +++ +H C+ C +C
Sbjct: 488 --ISALNTLWHPECFVCREC 505
Score = 74.3 bits (181), Expect = 2e-13
Identities = 83/324 (25%), Positives = 119/324 (36%), Gaps = 65/324 (20%)
Query: 86 AGSPRASLAGSDGGGGGGSARSSGISLGYDQRHGSPRSGRSDPRPGPGPPS------VGS 139
AG PR S GG G + G ++G S P GP P +GS
Sbjct: 293 AGWPRDGGRSSPGGQDEGGFMAQG------------KTGSSSPPGGPPKPGSQLDSMLGS 340
Query: 140 ARSSVSSLGSRGSAGAYADFLPPGACPAPARSPEPAGPAPFPLPALPLPPGREGGPS--- 196
+S ++ LG A GAC P AG + G+ P
Sbjct: 341 LQSDLNKLGVATVAKGVC-----GACKKPI-----AGQVVTAM-------GKTWHPEHFV 383
Query: 197 AAERRLEALTREL-ERALEARTARDYFGI----CIKCGLGIYGAQQACQAMGSLYHTDCF 251
+ E +R ER + +DY + C C I + A+ +H + F
Sbjct: 384 CTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWHPEHF 441
Query: 252 TCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHP 311
C CG + F+ K YC++D+ F A KC C I+E + AL +HP
Sbjct: 442 FCAQCGAFFGPEGFHEKDGKAYCRKDY----FDMFAPKCGGCARAILENYISALNTLWHP 497
Query: 312 GCFRCSVCNECLDGVPFT----VDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTI 367
CF VC EC PF + + YC YH C+ C +PI T
Sbjct: 498 ECF---VCRECF--TPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-------TGR 545
Query: 368 RVVSMDRDYHVACYHCEDCGLQLS 391
+ +M + +H + C C QL+
Sbjct: 546 CITAMAKKFHPEHFVCAFCLKQLN 569
Score = 66.2 bits (160), Expect = 5e-11
Identities = 39/128 (30%), Positives = 59/128 (46%), Gaps = 11/128 (8%)
Query: 290 CSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPK 349
C C I ++ A+GK++HP F C+ C E + F + + YC +DYH +F+P+
Sbjct: 358 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNF-FERDGQPYCEKDYHNLFSPR 416
Query: 350 CASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRR 409
C C PIL V ++DR +H + C CG G EG + G CR+
Sbjct: 417 CYYCNGPILDKV-------VTALDRTWHPEHFFCAQCG-AFFGPEG--FHEKDGKAYCRK 466
Query: 410 CHLRRLQP 417
+ P
Sbjct: 467 DYFDMFAP 474
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/140 (25%), Positives = 62/140 (44%), Gaps = 9/140 (6%)
Query: 210 ERALEARTARDYFGICI-KCGLGIYGA--QQACQAMGSLYHTDCFTCDSCGRRLRGKAFY 266
E+ +A +DYF + KCG G A + A+ +L+H +CF C C +F+
Sbjct: 457 EKDGKAYCRKDYFDMFAPKCG-GCARAILENYISALNTLWHPECFVCRECFTPFVNGSFF 515
Query: 267 NVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGV 326
+ YC+ + ++ CS C I + A+ K +HP F C+ C + L+
Sbjct: 516 EHDGQPYCEVHY----HERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 571
Query: 327 PFTVDVENNIYCVRDYHTVF 346
F + + YC + +F
Sbjct: 572 TFK-EQNDKPYCQNCFLKLF 590
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 89.4 bits (220), Expect = 6e-18
Identities = 53/198 (26%), Positives = 89/198 (44%), Gaps = 17/198 (8%)
Query: 189 PGREGGPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQACQAMGSLYHT 248
P ++ ++ + L L +EL+ A + G C C I G + A+G +H
Sbjct: 124 PDKQDHKASLDSMLGGLEQELQDLGIATVPK---GHCASCQKPIAG--KVIHALGQSWHP 178
Query: 249 DCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKS 308
+ F C C + F+ YC D+ Q + +C+ C I++ +L A+ ++
Sbjct: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDY----HQLFSPRCAYCAAPILDKVLTAMNQT 234
Query: 309 YHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIR 368
+HP F CS C E F + + YC +D+ +F+PKC C RP+L
Sbjct: 235 WHPEHFFCSHCGEVFGAEGFH-EKDKKPYCRKDFLAMFSPKCGGCNRPVLENY------- 286
Query: 369 VVSMDRDYHVACYHCEDC 386
+ +MD +H C+ C DC
Sbjct: 287 LSAMDTVWHPECFVCGDC 304
Score = 70.1 bits (170), Expect = 4e-12
Identities = 37/106 (34%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 290 CSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPK 349
C+ C I ++ ALG+S+HP F C+ C E + PF + YC DYH +F+P+
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPF-FERSGLAYCPNDYHQLFSPR 215
Query: 350 CASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEG 395
CA CA PIL + +M++ +H + C CG ++ G EG
Sbjct: 216 CAYCAAPILDKV-------LTAMNQTWHPEHFFCSHCG-EVFGAEG 253
Score = 70.1 bits (170), Expect = 4e-12
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 18/186 (9%)
Query: 210 ERALEARTARDYFGI----CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAF 265
ER+ A DY + C C I + AM +H + F C CG + F
Sbjct: 197 ERSGLAYCPNDYHQLFSPRCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGF 254
Query: 266 YNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDG 325
+ +K YC++DFL + KC C ++E L A+ +HP CF C C
Sbjct: 255 HEKDKKPYCRKDFL----AMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFST 310
Query: 326 VPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCED 385
F +++ +C YH C C +PI T + +M +H + C
Sbjct: 311 GSF-FELDGRPFCELHYHHRRGTLCHGCGQPI-------TGRCISAMGYKFHPEHFVCAF 362
Query: 386 CGLQLS 391
C QLS
Sbjct: 363 CLTQLS 368
Score = 34.7 bits (78), Expect = 0.17
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
Query: 224 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDF 278
+C CG I G + AMG +H + F C C +L F +K YCQ F
Sbjct: 333 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 89.4 bits (220), Expect = 6e-18
Identities = 53/198 (26%), Positives = 89/198 (44%), Gaps = 17/198 (8%)
Query: 189 PGREGGPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGAQQACQAMGSLYHT 248
P ++ ++ + L L +EL+ A + G C C I G + A+G +H
Sbjct: 119 PDKQDHKASLDSMLGGLEQELQDLGIATVPK---GHCASCQKPIAG--KVIHALGQSWHP 173
Query: 249 DCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKS 308
+ F C C + F+ YC D+ Q + +C+ C I++ +L A+ ++
Sbjct: 174 EHFVCTHCKEEIGSSPFFERSGLAYCPNDY----HQLFSPRCAYCAAPILDKVLTAMNQT 229
Query: 309 YHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIR 368
+HP F CS C E F + + YC +D+ +F+PKC C RP+L
Sbjct: 230 WHPEHFFCSHCGEVFGAEGFH-EKDKKPYCRKDFLAMFSPKCGGCNRPVLENY------- 281
Query: 369 VVSMDRDYHVACYHCEDC 386
+ +MD +H C+ C DC
Sbjct: 282 LSAMDTVWHPECFVCGDC 299
Score = 70.1 bits (170), Expect = 4e-12
Identities = 37/106 (34%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 290 CSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPK 349
C+ C I ++ ALG+S+HP F C+ C E + PF + YC DYH +F+P+
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPF-FERSGLAYCPNDYHQLFSPR 210
Query: 350 CASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEG 395
CA CA PIL + +M++ +H + C CG ++ G EG
Sbjct: 211 CAYCAAPILDKV-------LTAMNQTWHPEHFFCSHCG-EVFGAEG 248
Score = 70.1 bits (170), Expect = 4e-12
Identities = 50/186 (26%), Positives = 74/186 (39%), Gaps = 18/186 (9%)
Query: 210 ERALEARTARDYFGI----CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAF 265
ER+ A DY + C C I + AM +H + F C CG + F
Sbjct: 192 ERSGLAYCPNDYHQLFSPRCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGF 249
Query: 266 YNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDG 325
+ +K YC++DFL + KC C ++E L A+ +HP CF C C
Sbjct: 250 HEKDKKPYCRKDFL----AMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFST 305
Query: 326 VPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCED 385
F +++ +C YH C C +PI T + +M +H + C
Sbjct: 306 GSF-FELDGRPFCELHYHHRRGTLCHGCGQPI-------TGRCISAMGYKFHPEHFVCAF 357
Query: 386 CGLQLS 391
C QLS
Sbjct: 358 CLTQLS 363
Score = 34.7 bits (78), Expect = 0.17
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
Query: 224 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDF 278
+C CG I G + AMG +H + F C C +L F +K YCQ F
Sbjct: 328 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 380
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 88.2 bits (217), Expect = 1e-17
Identities = 54/178 (30%), Positives = 81/178 (45%), Gaps = 9/178 (5%)
Query: 217 TARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQE 276
T R+ C C I Q + G+++H DCFTC +C + + +F+ GE YC
Sbjct: 93 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYC-- 150
Query: 277 DFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNI 336
+ + A C C I + + +H CF C C++ L G FT VE+
Sbjct: 151 --VTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTA-VEDQY 207
Query: 337 YCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMD-RDYHVACYHCEDCGLQLSGE 393
YCV Y A KCA C PI G VV+ + + +H C+HC+ C + L+ +
Sbjct: 208 YCVDCYKNFVAKKCAGCKNPI---TGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANK 262
Score = 68.2 bits (165), Expect = 1e-11
Identities = 42/171 (24%), Positives = 70/171 (40%), Gaps = 14/171 (8%)
Query: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284
C++C I + +H CF C C L + F K+ C + +
Sbjct: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNK----CTTR 95
Query: 285 QTADKCSVCGHLIM--EMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDY 342
+ + KC C I+ + ++ G +H CF CS C + + F E + YCV +
Sbjct: 96 EDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGE-DFYCVTCH 154
Query: 343 HTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGE 393
T FA C C + I T+ + D+ +H C+ C C +L+G+
Sbjct: 155 ETKFAKHCVKCNKAI-------TSGGITYQDQPWHADCFVCVTCSKKLAGQ 198
Score = 30.8 bits (68), Expect = 2.5
Identities = 13/34 (38%), Positives = 16/34 (47%)
Query: 243 GSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQE 276
G +H CF C C L K F E+VYC +
Sbjct: 242 GQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 88.2 bits (217), Expect = 1e-17
Identities = 54/178 (30%), Positives = 81/178 (45%), Gaps = 9/178 (5%)
Query: 217 TARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQE 276
T R+ C C I Q + G+++H DCFTC +C + + +F+ GE YC
Sbjct: 93 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYC-- 150
Query: 277 DFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNI 336
+ + A C C I + + +H CF C C++ L G FT VE+
Sbjct: 151 --VTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTA-VEDQY 207
Query: 337 YCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMD-RDYHVACYHCEDCGLQLSGE 393
YCV Y A KCA C PI G VV+ + + +H C+HC+ C + L+ +
Sbjct: 208 YCVDCYKNFVAKKCAGCKNPI---TGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANK 262
Score = 68.2 bits (165), Expect = 1e-11
Identities = 42/171 (24%), Positives = 70/171 (40%), Gaps = 14/171 (8%)
Query: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284
C++C I + +H CF C C L + F K+ C + +
Sbjct: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNK----CTTR 95
Query: 285 QTADKCSVCGHLIM--EMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDY 342
+ + KC C I+ + ++ G +H CF CS C + + F E + YCV +
Sbjct: 96 EDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGE-DFYCVTCH 154
Query: 343 HTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGE 393
T FA C C + I T+ + D+ +H C+ C C +L+G+
Sbjct: 155 ETKFAKHCVKCNKAI-------TSGGITYQDQPWHADCFVCVTCSKKLAGQ 198
Score = 30.8 bits (68), Expect = 2.5
Identities = 13/34 (38%), Positives = 16/34 (47%)
Query: 243 GSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQE 276
G +H CF C C L K F E+VYC +
Sbjct: 242 GQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 88.2 bits (217), Expect = 1e-17
Identities = 54/178 (30%), Positives = 81/178 (45%), Gaps = 9/178 (5%)
Query: 217 TARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQE 276
T R+ C C I Q + G+++H DCFTC +C + + +F+ GE YC
Sbjct: 122 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYC-- 179
Query: 277 DFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNI 336
+ + A C C I + + +H CF C C++ L G FT VE+
Sbjct: 180 --VTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTA-VEDQY 236
Query: 337 YCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMD-RDYHVACYHCEDCGLQLSGE 393
YCV Y A KCA C PI G VV+ + + +H C+HC+ C + L+ +
Sbjct: 237 YCVDCYKNFVAKKCAGCKNPI---TGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANK 291
Score = 68.2 bits (165), Expect = 1e-11
Identities = 42/171 (24%), Positives = 70/171 (40%), Gaps = 14/171 (8%)
Query: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284
C++C I + +H CF C C L + F K+ C + +
Sbjct: 69 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNK----CTTR 124
Query: 285 QTADKCSVCGHLIM--EMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDY 342
+ + KC C I+ + ++ G +H CF CS C + + F E + YCV +
Sbjct: 125 EDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGE-DFYCVTCH 183
Query: 343 HTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGE 393
T FA C C + I T+ + D+ +H C+ C C +L+G+
Sbjct: 184 ETKFAKHCVKCNKAI-------TSGGITYQDQPWHADCFVCVTCSKKLAGQ 227
Score = 30.8 bits (68), Expect = 2.5
Identities = 13/34 (38%), Positives = 16/34 (47%)
Query: 243 GSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQE 276
G +H CF C C L K F E+VYC +
Sbjct: 271 GQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 304
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 88.2 bits (217), Expect = 1e-17
Identities = 54/178 (30%), Positives = 81/178 (45%), Gaps = 9/178 (5%)
Query: 217 TARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQE 276
T R+ C C I Q + G+++H DCFTC +C + + +F+ GE YC
Sbjct: 109 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYC-- 166
Query: 277 DFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNI 336
+ + A C C I + + +H CF C C++ L G FT VE+
Sbjct: 167 --VTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTA-VEDQY 223
Query: 337 YCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMD-RDYHVACYHCEDCGLQLSGE 393
YCV Y A KCA C PI G VV+ + + +H C+HC+ C + L+ +
Sbjct: 224 YCVDCYKNFVAKKCAGCKNPI---TGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANK 278
Score = 68.2 bits (165), Expect = 1e-11
Identities = 42/171 (24%), Positives = 70/171 (40%), Gaps = 14/171 (8%)
Query: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284
C++C I + +H CF C C L + F K+ C + +
Sbjct: 56 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNK----CTTR 111
Query: 285 QTADKCSVCGHLIM--EMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDY 342
+ + KC C I+ + ++ G +H CF CS C + + F E + YCV +
Sbjct: 112 EDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGE-DFYCVTCH 170
Query: 343 HTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGE 393
T FA C C + I T+ + D+ +H C+ C C +L+G+
Sbjct: 171 ETKFAKHCVKCNKAI-------TSGGITYQDQPWHADCFVCVTCSKKLAGQ 214
Score = 30.8 bits (68), Expect = 2.5
Identities = 13/34 (38%), Positives = 16/34 (47%)
Query: 243 GSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQE 276
G +H CF C C L K F E+VYC +
Sbjct: 258 GQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 291
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 88.2 bits (217), Expect = 1e-17
Identities = 54/178 (30%), Positives = 81/178 (45%), Gaps = 9/178 (5%)
Query: 217 TARDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQE 276
T R+ C C I Q + G+++H DCFTC +C + + +F+ GE YC
Sbjct: 93 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYC-- 150
Query: 277 DFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNI 336
+ + A C C I + + +H CF C C++ L G FT VE+
Sbjct: 151 --VTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTA-VEDQY 207
Query: 337 YCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMD-RDYHVACYHCEDCGLQLSGE 393
YCV Y A KCA C PI G VV+ + + +H C+HC+ C + L+ +
Sbjct: 208 YCVDCYKNFVAKKCAGCKNPI---TGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANK 262
Score = 68.2 bits (165), Expect = 1e-11
Identities = 42/171 (24%), Positives = 70/171 (40%), Gaps = 14/171 (8%)
Query: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284
C++C I + +H CF C C L + F K+ C + +
Sbjct: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNK----CTTR 95
Query: 285 QTADKCSVCGHLIM--EMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDY 342
+ + KC C I+ + ++ G +H CF CS C + + F E + YCV +
Sbjct: 96 EDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGE-DFYCVTCH 154
Query: 343 HTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGE 393
T FA C C + I T+ + D+ +H C+ C C +L+G+
Sbjct: 155 ETKFAKHCVKCNKAI-------TSGGITYQDQPWHADCFVCVTCSKKLAGQ 198
Score = 30.8 bits (68), Expect = 2.5
Identities = 13/34 (38%), Positives = 16/34 (47%)
Query: 243 GSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQE 276
G +H CF C C L K F E+VYC +
Sbjct: 242 GQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 88.2 bits (217), Expect = 1e-17
Identities = 54/190 (28%), Positives = 83/190 (43%), Gaps = 17/190 (8%)
Query: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284
C +C G A++ + G LYH CF C C ++ FY + YC+ DF
Sbjct: 10 CERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ----M 65
Query: 285 QTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHT 344
A C CG I+ +++A+ S+HP CFRC +C E L + F + ++ R H
Sbjct: 66 LFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHL--CRPCHN 123
Query: 345 VFAPKCASCARPILPAQGCETTI---RVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPL 401
K + I Q C I ++ + YH ++C +CG +L+ + L
Sbjct: 124 --REKARGLGKYI--CQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTAD----AREL 175
Query: 402 AGHLLCRRCH 411
G L C CH
Sbjct: 176 KGELYCLPCH 185
Score = 56.2 bits (134), Expect = 6e-08
Identities = 38/123 (30%), Positives = 51/123 (41%), Gaps = 8/123 (6%)
Query: 200 RRLEALTRELERALEARTARDYFG--ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCG 257
+ L A REL+ L D G IC C I G + AMG +H + F C C
Sbjct: 166 KELTADARELKGELYCLPCHDKMGVPICGACRRPIEG--RVVNAMGKQWHVEHFVCAKCE 223
Query: 258 RRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCS 317
+ G Y YC+ + Q D C C +I ++ AL K++ CF CS
Sbjct: 224 KPFLGHRHYERKGLAYCETHYN----QLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACS 279
Query: 318 VCN 320
CN
Sbjct: 280 TCN 282
Score = 55.5 bits (132), Expect = 9e-08
Identities = 41/136 (30%), Positives = 60/136 (44%), Gaps = 18/136 (13%)
Query: 286 TADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVP--FTVDVENNIYCVRDYH 343
T ++C G E I+ + G+ YH CF VC +C P + E YC D+
Sbjct: 9 TCERCKG-GFAPAEKIVNSNGELYHEQCF---VCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
Query: 344 TVFAPKCASCARPILPAQGCETTIRVV-SMDRDYHVACYHCEDCGLQLSGEEGRRCYPLA 402
+FAP C C I+ RV+ +M+ +H C+ C+ C ++ + G A
Sbjct: 65 MLFAPCCHQCGEFIIG--------RVIKAMNNSWHPECFRCDLCQ-EVLADIG--FVKNA 113
Query: 403 GHLLCRRCHLRRLQPG 418
G LCR CH R G
Sbjct: 114 GRHLCRPCHNREKARG 129
Score = 53.9 bits (128), Expect = 3e-07
Identities = 46/168 (27%), Positives = 70/168 (41%), Gaps = 15/168 (8%)
Query: 224 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGF 283
IC KC I +Q YH D F C +CG+ L A GE +YC L
Sbjct: 134 ICQKCHAII--DEQPLIFKNDPYHPDHFNCANCGKELTADARELKGE-LYC----LPCHD 186
Query: 284 QQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYH 343
+ C C I ++ A+GK +H F C+ C + G + + YC Y+
Sbjct: 187 KMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRH-YERKGLAYCETHYN 245
Query: 344 TVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLS 391
+F C C R I E + V ++++ + V C+ C C +L+
Sbjct: 246 QLFGDVCFHCNRVI------EGDV-VSALNKAWCVNCFACSTCNTKLT 286
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 85.9 bits (211), Expect = 6e-17
Identities = 51/177 (28%), Positives = 77/177 (43%), Gaps = 20/177 (11%)
Query: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284
C KCG G + + +H CFTC CG L F+ + C D+ +
Sbjct: 39 CHKCGEPCKG--EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQ----R 92
Query: 285 QTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECL---DGVPFTVDVENNIYCVRD 341
+C CG + ++ ALGK+YHP CF C++C D V F C +
Sbjct: 93 MYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQP 152
Query: 342 Y-----HTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGE 393
T F+ CA C R I Q ++++D+ +H+ C+ C+ CG L+GE
Sbjct: 153 MSSSPKETTFSSNCAGCGRDIKNGQA------LLALDKQWHLGCFKCKSCGKVLTGE 203
Score = 72.8 bits (177), Expect = 6e-13
Identities = 57/184 (30%), Positives = 81/184 (44%), Gaps = 20/184 (10%)
Query: 219 RDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLR--GKAFYNVGEKVYCQ- 275
R Y C CG + G + A+G YH +CF C C R + +N G CQ
Sbjct: 92 RMYGTRCHGCGEFVEG--EVVTALGKTYHPNCFACTICKRPFPPGDRVTFN-GRDCLCQL 148
Query: 276 -EDFLYSGFQQT--ADKCSVCGHLIME-MILQALGKSYHPGCFRCSVCNECLDGVPFTVD 331
+ S ++T + C+ CG I L AL K +H GCF+C C + L G + D
Sbjct: 149 CAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKD 208
Query: 332 VENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLS 391
YC +DY +F KC +C + I T + + D+ YH +C C C +
Sbjct: 209 --GAPYCEKDYQGLFGVKCEACHQFI-------TGKVLEAGDKHYHPSCARCSRCNQMFT 259
Query: 392 -GEE 394
GEE
Sbjct: 260 EGEE 263
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 85.9 bits (211), Expect = 6e-17
Identities = 51/177 (28%), Positives = 77/177 (43%), Gaps = 20/177 (11%)
Query: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284
C KCG G + + +H CFTC CG L F+ + C D+ +
Sbjct: 39 CHKCGEPCKG--EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQ----R 92
Query: 285 QTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECL---DGVPFTVDVENNIYCVRD 341
+C CG + ++ ALGK+YHP CF C++C D V F C +
Sbjct: 93 MYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQP 152
Query: 342 Y-----HTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGE 393
T F+ CA C R I Q ++++D+ +H+ C+ C+ CG L+GE
Sbjct: 153 MSSSPKETTFSSNCAGCGRDIKNGQA------LLALDKQWHLGCFKCKSCGKVLTGE 203
Score = 72.8 bits (177), Expect = 6e-13
Identities = 57/184 (30%), Positives = 81/184 (44%), Gaps = 20/184 (10%)
Query: 219 RDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLR--GKAFYNVGEKVYCQ- 275
R Y C CG + G + A+G YH +CF C C R + +N G CQ
Sbjct: 92 RMYGTRCHGCGEFVEG--EVVTALGKTYHPNCFACTICKRPFPPGDRVTFN-GRDCLCQL 148
Query: 276 -EDFLYSGFQQT--ADKCSVCGHLIME-MILQALGKSYHPGCFRCSVCNECLDGVPFTVD 331
+ S ++T + C+ CG I L AL K +H GCF+C C + L G + D
Sbjct: 149 CAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKD 208
Query: 332 VENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLS 391
YC +DY +F KC +C + I T + + D+ YH +C C C +
Sbjct: 209 --GAPYCEKDYQGLFGVKCEACHQFI-------TGKVLEAGDKHYHPSCARCSRCNQMFT 259
Query: 392 -GEE 394
GEE
Sbjct: 260 EGEE 263
>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
Length = 778
Score = 85.9 bits (211), Expect = 6e-17
Identities = 51/177 (28%), Positives = 77/177 (43%), Gaps = 20/177 (11%)
Query: 225 CIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQ 284
C KCG G + + +H CFTC CG L F+ + C D+ +
Sbjct: 99 CHKCGEPCKG--EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQ----R 152
Query: 285 QTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECL---DGVPFTVDVENNIYCVRD 341
+C CG + ++ ALGK+YHP CF C++C D V F C +
Sbjct: 153 MYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQP 212
Query: 342 Y-----HTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGE 393
T F+ CA C R I Q ++++D+ +H+ C+ C+ CG L+GE
Sbjct: 213 MSSSPKETTFSSNCAGCGRDIKNGQA------LLALDKQWHLGCFKCKSCGKVLTGE 263
Score = 72.8 bits (177), Expect = 6e-13
Identities = 57/184 (30%), Positives = 81/184 (44%), Gaps = 20/184 (10%)
Query: 219 RDYFGICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLR--GKAFYNVGEKVYCQ- 275
R Y C CG + G + A+G YH +CF C C R + +N G CQ
Sbjct: 152 RMYGTRCHGCGEFVEG--EVVTALGKTYHPNCFACTICKRPFPPGDRVTFN-GRDCLCQL 208
Query: 276 -EDFLYSGFQQT--ADKCSVCGHLIME-MILQALGKSYHPGCFRCSVCNECLDGVPFTVD 331
+ S ++T + C+ CG I L AL K +H GCF+C C + L G + D
Sbjct: 209 CAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKD 268
Query: 332 VENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLS 391
YC +DY +F KC +C + I T + + D+ YH +C C C +
Sbjct: 269 --GAPYCEKDYQGLFGVKCEACHQFI-------TGKVLEAGDKHYHPSCARCSRCNQMFT 319
Query: 392 -GEE 394
GEE
Sbjct: 320 EGEE 323
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 84.3 bits (207), Expect = 2e-16
Identities = 54/191 (28%), Positives = 81/191 (42%), Gaps = 17/191 (8%)
Query: 224 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGF 283
+C +C A++ + G LYH CF C C R FY + YC+ DF
Sbjct: 36 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQ---- 91
Query: 284 QQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYH 343
A C CG I+ +++A+ ++HPGCFRC +C+ L + F + ++ R H
Sbjct: 92 MLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHL--CRPCH 149
Query: 344 TVFAPKCASCARPILPAQGCETTI---RVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYP 400
K + I Q C I ++ YH ++C CG +L+ E
Sbjct: 150 N--REKAKGLGKYI--CQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAE----ARE 201
Query: 401 LAGHLLCRRCH 411
L G L C CH
Sbjct: 202 LKGELYCLPCH 212
Score = 61.6 bits (148), Expect = 1e-09
Identities = 40/123 (32%), Positives = 57/123 (46%), Gaps = 17/123 (13%)
Query: 299 EMILQALGKSYHPGCFRCSVCNECLDGVP--FTVDVENNIYCVRDYHTVFAPKCASCARP 356
E I+ + G+ YH CF VC +C P + E YC D+ +FAP C SC
Sbjct: 48 ERIVNSNGELYHEHCF---VCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEF 104
Query: 357 ILPAQGCETTIRVV-SMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRRCHLRRL 415
I+ RV+ +M+ ++H C+ CE C ++L+ AG LCR CH R
Sbjct: 105 IIG--------RVIKAMNNNWHPGCFRCELCDVELAD---LGFVKNAGRHLCRPCHNREK 153
Query: 416 QPG 418
G
Sbjct: 154 AKG 156
Score = 60.5 bits (145), Expect = 3e-09
Identities = 43/145 (29%), Positives = 59/145 (40%), Gaps = 8/145 (5%)
Query: 200 RRLEALTRELERALEARTARDYFG--ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCG 257
+ L A REL+ L D G IC C I G + A+G +H + F C C
Sbjct: 193 KELTAEARELKGELYCLPCHDKMGVPICGACRRPIEG--RVVNALGKQWHVEHFVCAKCE 250
Query: 258 RRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCS 317
+ G Y YC+ + Q D C C H+I ++ AL K++ CF CS
Sbjct: 251 KPFLGHRHYEKKGLAYCETHYN----QLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 306
Query: 318 VCNECLDGVPFTVDVENNIYCVRDY 342
CN L V+ + C R Y
Sbjct: 307 TCNSKLTLKNKFVEFDMKPVCKRCY 331
Score = 60.1 bits (144), Expect = 4e-09
Identities = 49/188 (26%), Positives = 81/188 (43%), Gaps = 17/188 (9%)
Query: 224 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGF 283
IC +C L I +Q YH D F C CG+ L +A GE +YC L
Sbjct: 161 ICQRCHLVI--DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYC----LPCHD 213
Query: 284 QQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYH 343
+ C C I ++ ALGK +H F C+ C + G + + YC Y+
Sbjct: 214 KMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRH-YEKKGLAYCETHYN 272
Query: 344 TVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAG 403
+F C +C+ I E + V ++++ + V+C+ C C +L+ + +
Sbjct: 273 QLFGDVCYNCSHVI------EGDV-VSALNKAWCVSCFSCSTCNSKLTLK--NKFVEFDM 323
Query: 404 HLLCRRCH 411
+C+RC+
Sbjct: 324 KPVCKRCY 331
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 84.3 bits (207), Expect = 2e-16
Identities = 54/191 (28%), Positives = 81/191 (42%), Gaps = 17/191 (8%)
Query: 224 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGF 283
+C +C A++ + G LYH CF C C R FY + YC+ DF
Sbjct: 9 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQ---- 64
Query: 284 QQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYH 343
A C CG I+ +++A+ ++HPGCFRC +C+ L + F + ++ R H
Sbjct: 65 MLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHL--CRPCH 122
Query: 344 TVFAPKCASCARPILPAQGCETTI---RVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYP 400
K + I Q C I ++ YH ++C CG +L+ E
Sbjct: 123 N--REKAKGLGKYI--CQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAE----ARE 174
Query: 401 LAGHLLCRRCH 411
L G L C CH
Sbjct: 175 LKGELYCLPCH 185
Score = 61.6 bits (148), Expect = 1e-09
Identities = 40/123 (32%), Positives = 57/123 (46%), Gaps = 17/123 (13%)
Query: 299 EMILQALGKSYHPGCFRCSVCNECLDGVP--FTVDVENNIYCVRDYHTVFAPKCASCARP 356
E I+ + G+ YH CF VC +C P + E YC D+ +FAP C SC
Sbjct: 21 ERIVNSNGELYHEHCF---VCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEF 77
Query: 357 ILPAQGCETTIRVV-SMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRRCHLRRL 415
I+ RV+ +M+ ++H C+ CE C ++L+ AG LCR CH R
Sbjct: 78 IIG--------RVIKAMNNNWHPGCFRCELCDVELAD---LGFVKNAGRHLCRPCHNREK 126
Query: 416 QPG 418
G
Sbjct: 127 AKG 129
Score = 60.5 bits (145), Expect = 3e-09
Identities = 43/145 (29%), Positives = 59/145 (40%), Gaps = 8/145 (5%)
Query: 200 RRLEALTRELERALEARTARDYFG--ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCG 257
+ L A REL+ L D G IC C I G + A+G +H + F C C
Sbjct: 166 KELTAEARELKGELYCLPCHDKMGVPICGACRRPIEG--RVVNALGKQWHVEHFVCAKCE 223
Query: 258 RRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCS 317
+ G Y YC+ + Q D C C H+I ++ AL K++ CF CS
Sbjct: 224 KPFLGHRHYEKKGLAYCETHYN----QLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 279
Query: 318 VCNECLDGVPFTVDVENNIYCVRDY 342
CN L V+ + C R Y
Sbjct: 280 TCNSKLTLKNKFVEFDMKPVCKRCY 304
Score = 60.1 bits (144), Expect = 4e-09
Identities = 49/188 (26%), Positives = 81/188 (43%), Gaps = 17/188 (9%)
Query: 224 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGF 283
IC +C L I +Q YH D F C CG+ L +A GE +YC L
Sbjct: 134 ICQRCHLVI--DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYC----LPCHD 186
Query: 284 QQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYH 343
+ C C I ++ ALGK +H F C+ C + G + + YC Y+
Sbjct: 187 KMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRH-YEKKGLAYCETHYN 245
Query: 344 TVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAG 403
+F C +C+ I E + V ++++ + V+C+ C C +L+ + +
Sbjct: 246 QLFGDVCYNCSHVI------EGDV-VSALNKAWCVSCFSCSTCNSKLTLK--NKFVEFDM 296
Query: 404 HLLCRRCH 411
+C+RC+
Sbjct: 297 KPVCKRCY 304
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 84.3 bits (207), Expect = 2e-16
Identities = 54/191 (28%), Positives = 81/191 (42%), Gaps = 17/191 (8%)
Query: 224 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGF 283
+C +C A++ + G LYH CF C C R FY + YC+ DF
Sbjct: 14 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQ---- 69
Query: 284 QQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYH 343
A C CG I+ +++A+ ++HPGCFRC +C+ L + F + ++ R H
Sbjct: 70 MLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHL--CRPCH 127
Query: 344 TVFAPKCASCARPILPAQGCETTI---RVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYP 400
K + I Q C I ++ YH ++C CG +L+ E
Sbjct: 128 N--REKAKGLGKYI--CQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAE----ARE 179
Query: 401 LAGHLLCRRCH 411
L G L C CH
Sbjct: 180 LKGELYCLPCH 190
Score = 61.6 bits (148), Expect = 1e-09
Identities = 40/123 (32%), Positives = 57/123 (46%), Gaps = 17/123 (13%)
Query: 299 EMILQALGKSYHPGCFRCSVCNECLDGVP--FTVDVENNIYCVRDYHTVFAPKCASCARP 356
E I+ + G+ YH CF VC +C P + E YC D+ +FAP C SC
Sbjct: 26 ERIVNSNGELYHEHCF---VCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEF 82
Query: 357 ILPAQGCETTIRVV-SMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAGHLLCRRCHLRRL 415
I+ RV+ +M+ ++H C+ CE C ++L+ AG LCR CH R
Sbjct: 83 IIG--------RVIKAMNNNWHPGCFRCELCDVELAD---LGFVKNAGRHLCRPCHNREK 131
Query: 416 QPG 418
G
Sbjct: 132 AKG 134
Score = 60.5 bits (145), Expect = 3e-09
Identities = 43/145 (29%), Positives = 59/145 (40%), Gaps = 8/145 (5%)
Query: 200 RRLEALTRELERALEARTARDYFG--ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCG 257
+ L A REL+ L D G IC C I G + A+G +H + F C C
Sbjct: 171 KELTAEARELKGELYCLPCHDKMGVPICGACRRPIEG--RVVNALGKQWHVEHFVCAKCE 228
Query: 258 RRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCS 317
+ G Y YC+ + Q D C C H+I ++ AL K++ CF CS
Sbjct: 229 KPFLGHRHYEKKGLAYCETHYN----QLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCS 284
Query: 318 VCNECLDGVPFTVDVENNIYCVRDY 342
CN L V+ + C R Y
Sbjct: 285 TCNSKLTLKNKFVEFDMKPVCKRCY 309
Score = 60.1 bits (144), Expect = 4e-09
Identities = 49/188 (26%), Positives = 81/188 (43%), Gaps = 17/188 (9%)
Query: 224 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGF 283
IC +C L I +Q YH D F C CG+ L +A GE +YC L
Sbjct: 139 ICQRCHLVI--DEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYC----LPCHD 191
Query: 284 QQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYH 343
+ C C I ++ ALGK +H F C+ C + G + + YC Y+
Sbjct: 192 KMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRH-YEKKGLAYCETHYN 250
Query: 344 TVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYHCEDCGLQLSGEEGRRCYPLAG 403
+F C +C+ I E + V ++++ + V+C+ C C +L+ + +
Sbjct: 251 QLFGDVCYNCSHVI------EGDV-VSALNKAWCVSCFSCSTCNSKLTLK--NKFVEFDM 301
Query: 404 HLLCRRCH 411
+C+RC+
Sbjct: 302 KPVCKRCY 309
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.139 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,356,855
Number of Sequences: 37866
Number of extensions: 1635409
Number of successful extensions: 26373
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 506
Number of HSP's successfully gapped in prelim test: 2044
Number of HSP's that attempted gapping in prelim test: 13404
Number of HSP's gapped (non-prelim): 9631
length of query: 430
length of database: 18,247,518
effective HSP length: 105
effective length of query: 325
effective length of database: 14,271,588
effective search space: 4638266100
effective search space used: 4638266100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.