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Search of human proteins with 29294627
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29294627 PTPRF interacting protein binding protein 1 isoform
1 [Homo sapiens]
(1005 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29294627 PTPRF interacting protein binding protein 1 isoform ... 1989 0.0
gi|170784854 PTPRF interacting protein, binding protein 2 (lipri... 693 0.0
gi|29294629 PTPRF interacting protein binding protein 1 isoform ... 311 2e-84
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 159 1e-38
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 159 1e-38
gi|157837985 kazrin isoform E [Homo sapiens] 158 2e-38
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 155 1e-37
gi|55769554 protein tyrosine phosphatase, receptor type, f polyp... 146 1e-34
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] 143 9e-34
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 70 1e-11
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 69 3e-11
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 69 3e-11
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 69 3e-11
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 69 3e-11
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 68 4e-11
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 68 4e-11
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 68 4e-11
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 68 4e-11
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 67 6e-11
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 67 8e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 64 5e-10
gi|156104908 myosin heavy chain 6 [Homo sapiens] 64 9e-10
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 63 1e-09
gi|42794779 myosin 18A isoform b [Homo sapiens] 63 2e-09
gi|28416946 myosin 18A isoform a [Homo sapiens] 63 2e-09
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 62 3e-09
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 62 3e-09
gi|34577114 cytomatrix protein p110 [Homo sapiens] 62 3e-09
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 61 5e-09
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 61 5e-09
>gi|29294627 PTPRF interacting protein binding protein 1 isoform 1
[Homo sapiens]
Length = 1005
Score = 1989 bits (5152), Expect = 0.0
Identities = 1005/1005 (100%), Positives = 1005/1005 (100%)
Query: 1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE 60
MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
Sbjct: 1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE 60
Query: 61 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV 120
MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
Sbjct: 61 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV 120
Query: 121 SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLK 180
SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLK
Sbjct: 121 SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLK 180
Query: 181 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKE 240
LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKE
Sbjct: 181 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKE 240
Query: 241 QLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANE 300
QLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANE
Sbjct: 241 QLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANE 300
Query: 301 EKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNSSSISSLLDAQGFSDLEKS 360
EKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNSSSISSLLDAQGFSDLEKS
Sbjct: 301 EKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNSSSISSLLDAQGFSDLEKS 360
Query: 361 PSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETSEKSKLTPKPETSFEE 420
PSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETSEKSKLTPKPETSFEE
Sbjct: 361 PSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETSEKSKLTPKPETSFEE 420
Query: 421 NDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESRPF 480
NDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESRPF
Sbjct: 421 NDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESRPF 480
Query: 481 GTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAE 540
GTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAE
Sbjct: 481 GTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAE 540
Query: 541 TEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTTFNP 600
TEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTTFNP
Sbjct: 541 TEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTTFNP 600
Query: 601 DDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQGLGSYLN 660
DDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQGLGSYLN
Sbjct: 601 DDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQGLGSYLN 660
Query: 661 SGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLDFNWVTR 720
SGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLDFNWVTR
Sbjct: 661 SGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLDFNWVTR 720
Query: 721 WLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEP 780
WLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEP
Sbjct: 721 WLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEP 780
Query: 781 NCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNV 840
NCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNV
Sbjct: 781 NCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNV 840
Query: 841 ETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLA 900
ETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLA
Sbjct: 841 ETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLA 900
Query: 901 FSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLEQMEDSE 960
FSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLEQMEDSE
Sbjct: 901 FSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLEQMEDSE 960
Query: 961 GTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV 1005
GTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
Sbjct: 961 GTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV 1005
>gi|170784854 PTPRF interacting protein, binding protein 2 (liprin
beta 2) [Homo sapiens]
Length = 876
Score = 693 bits (1789), Expect = 0.0
Identities = 432/977 (44%), Positives = 568/977 (58%), Gaps = 123/977 (12%)
Query: 1 MMSDASDMLAAALEQMDGIIAGSKA-LEYSNGIFD--CQSPTSPFMGSLRALHLVEDLRG 57
M SDAS L AALEQMDGIIAG+K + S+G + SP S +M LHL+EDLR
Sbjct: 1 MASDASHALEAALEQMDGIIAGTKTGADLSDGTCEPGLASPAS-YMNPFPVLHLIEDLRL 59
Query: 58 LLEMMET-DEKEGLRCQIPDSTAETLVEWLQSQMT--NGHLPGNGDVYQERLARLENDKE 114
LEM+E E+ L QIP TA + EW + ++ N H + + YQERLARLE DKE
Sbjct: 60 ALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKE 119
Query: 115 SLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMA 174
SL+LQVSVLTDQVEAQGEKIRDLE CLE H+ K+NA EEMLQQELLSRTSLETQKLDLM
Sbjct: 120 SLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMT 179
Query: 175 EISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDE 234
E+S LKLKL +EK++ + E+K R E L+QE+ L++KV E+++ER QYE KLK+TK
Sbjct: 180 EVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK-- 237
Query: 235 LASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVES 294
+EV +LQE++ K + E++++ +
Sbjct: 238 ------------AEVAQLQEQVALK----------------------DAEIERLHSQLSR 263
Query: 295 LMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEEL---LNS--SSISSLL 349
A + E + + Q + R K +T++LA + KD EEL LN ++
Sbjct: 264 TAALHSESHTERD---QEIQRLKMGMETLLLAN--EDKDRRIEELTGLLNQYRKVKEIVM 318
Query: 350 DAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTIL--QVSIPSLLPATVSMETSEK 407
QG S+ S + G S PEE + + S P++ P
Sbjct: 319 VTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPP--------- 369
Query: 408 SKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQK 467
P P+ S E K L+ SL E ++
Sbjct: 370 ----PLPQKSLETR--------------AQKKLSCSL------------------EDLRS 393
Query: 468 TSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNL 527
S D+ ++PF L P+ D+PF + N A +P
Sbjct: 394 ESVDKCMDGNQPFPVLEPK---------DSPFLAEHKYPTLPGKLSGATPNGEAAKSPPT 444
Query: 528 DRKRSASAPTLA---ETEK---ETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSR 581
+ A+ +L +TE +TA DL+ SS + ++ P +PD K+ +
Sbjct: 445 ICQPDATGSSLLRLRDTESGWDDTAVVNDLSSTSSGTESGPQS------PLTPDGKRNPK 498
Query: 582 GIMKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKW 641
GI K +GK+RR+QS F D + EF+RGG RATAGPRL +RD SD + PFA+W
Sbjct: 499 GIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSRTRDSKGQKSDANAPFAQW 558
Query: 642 TKEQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQA 701
+ E+VC WL + GL Y+ + W++SG TLL A+ QD+EKELGIKH LHRKKL LA++A
Sbjct: 559 STERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKA 618
Query: 702 LGSEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVL 761
+ +++E LD WVTRWLDDIGLPQYK QF E RVDGRML Y+TV+DLL LKV S L
Sbjct: 619 INTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQL 678
Query: 762 HHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPN 821
HHLSIK AI VL +N F P+CL RRP+DE+ ++PSEV +W+NHRVMEWLRSVDLAEYAPN
Sbjct: 679 HHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPN 738
Query: 822 LRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAME 881
LRGSGVHGGL++LEPRF +T+A LLNIPP KTLLRRHL T FN LIG EA+ +KR+ M
Sbjct: 739 LRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKREKMA 798
Query: 882 LPDYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASK--KGFKPG 939
P Y LT TAKV+P+KL FS+FGN+RKKK ++ +Y+CPME + + G++
Sbjct: 799 SPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPMEPSDGVSDSHRVYSGYRGL 858
Query: 940 LDMRLYEEDDLDRLEQM 956
+ E D LD++ Q+
Sbjct: 859 SPLDAPELDGLDQVGQI 875
>gi|29294629 PTPRF interacting protein binding protein 1 isoform 2
[Homo sapiens]
Length = 170
Score = 311 bits (797), Expect = 2e-84
Identities = 157/157 (100%), Positives = 157/157 (100%)
Query: 1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE 60
MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
Sbjct: 1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE 60
Query: 61 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV 120
MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
Sbjct: 61 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV 120
Query: 121 SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQ 157
SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQ
Sbjct: 121 SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQ 157
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 159 bits (402), Expect = 1e-38
Identities = 218/920 (23%), Positives = 378/920 (41%), Gaps = 130/920 (14%)
Query: 53 EDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLEND 112
EDL ++E+ E K+ S + + L S +T L + D ++ L + E
Sbjct: 247 EDLAKVIELQEIISKQSRE----QSQMKERLASLSSHVTE--LEEDLDTARKDLIKSEEM 300
Query: 113 KESLVLQVSVLTDQVEAQGEKIRDLE---FCLEEHREKVNATEEMLQQELLSRTSLETQK 169
L V Q E E+I LE + V+ + L+ E+ ++ S+ Q
Sbjct: 301 NTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQT 360
Query: 170 LDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLK 229
D ++ +L+L E K + T + + ++ ++++ + + E++
Sbjct: 361 EDKNRQLQE-RLELA---------EQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHG 410
Query: 230 STKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMK 289
+ ++ L ++ QLEEK E++R +++ KM E + + + K L E N ++++
Sbjct: 411 NIEERLRQMEAQLEEKNQELQRARQRE--KMNEEHNKRLS--DTVDKLLSESN---ERLQ 463
Query: 290 KAVESLMAANEEKD---RKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNSSSIS 346
++ MAA E+K+ R++E ++ L + +D +VL + ++ L +S
Sbjct: 464 LHLKERMAALEDKNSLLREVESAKKQLEETQHDKDQLVLNIEALRAELDHMRLRGASL-- 521
Query: 347 SLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSV----PEEFHTTILQVSIPSLLPATVSM 402
G L P M D ++TS P++ L+ PS +
Sbjct: 522 ----HHGRPHLGSVPDFRFPMADGHTDSYSTSAVLRRPQKGRLAALRDE-PSKVQTLNEQ 576
Query: 403 --ETSEKSKLTPKPETSFEENDGNIILGATV-DTQLC--DKLLTSSLQKSSSLGNLKKET 457
E ++++ + +FE +D ++ G DT L D L S + +L + +E
Sbjct: 577 DWERAQQASVLANVAQAFE-SDADVSDGEDDRDTLLSSVDLLSPSGQADAHTLAMMLQEQ 635
Query: 458 SDGEKETIQKTSEDRAPAESRP--------------------FGTLPPRPPGQDTSMDDN 497
D + I+ E++ E R ++PP P S
Sbjct: 636 LDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPPYPASSLASSSPP 695
Query: 498 PFGT---RKVRSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAETEK----------- 543
G R++ S R ++ T P+ + R ET
Sbjct: 696 GSGRSTPRRIPHSPAREVDRL--GVMTLLPPSREEVRDDKTTIKCETSPPSSPRALRLDR 753
Query: 544 ------ETAEHLDL------AGASSRP--KDSQRNSPFQIPPPSPDSKKKSRGIMKLFGK 589
T H D+ G+ P S NS +P K I +LFGK
Sbjct: 754 LHKGALHTVSHEDIRDIRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGK 813
Query: 590 LRRS-----------QSTTFNPDDMSEPEF---KRGGTRATAGPRLGWSRDLGQSNSDLD 635
+ Q+ D+ S+ K GG +A +L +L +
Sbjct: 814 KEKGRPGQTGKEALGQAGVSETDNSSQDALGLSKLGG-QAEKNRKLQKKHELLEEARRQG 872
Query: 636 MPFAKWTKEQVCNWLMEQGLGS---YLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHR 692
+PFA+W V WL E +G Y+ + + + SG + S ++++E+GI + LHR
Sbjct: 873 LPFAQWDGPTVVVWL-ELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHR 931
Query: 693 KKLQLALQALGSEEETN----------HGKLDFNWV-TRWLDDIGLPQYKTQFDEGRVDG 741
KL+LA+Q + S + +G ++ W+ WL +GLPQY++ F E VD
Sbjct: 932 LKLRLAIQEIMSLTSPSAPPTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDA 991
Query: 742 RMLHYMTVDDLLS-LKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQK 800
RML ++T DL LK+V H S + I LR N++ L R+ +E+ +V
Sbjct: 992 RMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERK-REESQSEIKDVLV 1050
Query: 801 WTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHL 860
W+N RV+ W+ S+ L EYA NL SGVHG L+ L+ F+ +A LL IP T R L
Sbjct: 1051 WSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVL 1110
Query: 861 ATHFN--LLIGAEAQHQKRD 878
FN L++G + + + D
Sbjct: 1111 EREFNNLLVMGTDRRFDEDD 1130
Score = 52.8 bits (125), Expect = 2e-06
Identities = 175/850 (20%), Positives = 327/850 (38%), Gaps = 162/850 (19%)
Query: 60 EMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDV-YQERLARLENDKESLVL 118
E+M E+ + + D + E + T+G +G + ++E LA++ +E +
Sbjct: 202 ELMILKEQNNQKKTLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISK 261
Query: 119 QV---SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAE 175
Q S + +++ + + +LE L+ R+ + +EEM T L+ + MA+
Sbjct: 262 QSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEM-------NTKLQRDVREAMAQ 314
Query: 176 ISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEIND-LRLKVSEMDSERLQYEKKLKSTKDE 234
+++ ++T +EK L + + + ++ND L +++ DS Q E K + ++
Sbjct: 315 KEDMEERITTLEKRYLAAQREATS----VHDLNDKLENEIANKDSMHRQTEDKNRQLQER 370
Query: 235 LASLKEQLEEKESEVKRLQE---------KLVCKMKGEGVEIVDRDENFKKKLKEKNIEV 285
L +++L++ + + L E + K + I +R + +L+EKN E+
Sbjct: 371 LELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQEL 430
Query: 286 QKMKKAVESLMAANEEKDRKIEDLRQCL-------------NRYKKMQDTVVLAQGKKGK 332
Q+ ++ + NEE ++++ D L R ++D L + +
Sbjct: 431 QRARQREK----MNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVESA 486
Query: 333 DGEYEE--------LLNSSSISSLLD---------AQGFSDLEKSPSPTPVMGSPSCDPF 375
+ EE +LN ++ + LD G L P M D +
Sbjct: 487 KKQLEETQHDKDQLVLNIEALRAELDHMRLRGASLHHGRPHLGSVPDFRFPMADGHTDSY 546
Query: 376 NTSV----PEEFHTTILQVSIPSLLPA--TVSMETSEKSKLTPKPETSFEENDGNIILGA 429
+TS P++ L+ PS + E ++++ + +F E+D ++ G
Sbjct: 547 STSAVLRRPQKGRLAALR-DEPSKVQTLNEQDWERAQQASVLANVAQAF-ESDADVSDGE 604
Query: 430 -TVDTQL--CDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESRPFGTLPPR 486
DT L D L S + +L + +E D + I+ E++ E R
Sbjct: 605 DDRDTLLSSVDLLSPSGQADAHTLAMMLQEQLDAINKEIRLIQEEKENTEQR-------- 656
Query: 487 PPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAETEKETA 546
++ S G G S NL R RS S+ A
Sbjct: 657 --------------AEEIESRVGSG-----------SLDNLGRFRSMSS-----IPPYPA 686
Query: 547 EHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLR---RSQSTTF----- 598
L ASS P S R++P +I P SP + G+M L R R TT
Sbjct: 687 SSL----ASSSPPGSGRSTPRRI-PHSPAREVDRLGVMTLLPPSREEVRDDKTTIKCETS 741
Query: 599 ---NPDDMSEPEFKRGG-----------TRATAGPRLGWSRDLGQSNSDLD----MPFAK 640
+P + +G R + G + G + SNS D P K
Sbjct: 742 PPSSPRALRLDRLHKGALHTVSHEDIRDIRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKK 801
Query: 641 WTKEQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIK----HSLHRKKLQ 696
K + ++ G +GK A GQ + + + LG+ + +KLQ
Sbjct: 802 GIKSSIGRLFGKKEKGRPGQTGKE--ALGQAGVSETDNSSQDALGLSKLGGQAEKNRKLQ 859
Query: 697 LALQALGSEEETNHGKLDFNW----VTRWLD-DIGLPQYKTQFDEGRV-DGRMLHYMTVD 750
+ L EE G W V WL+ +G+P + V G ++ ++
Sbjct: 860 KKHELL--EEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDT 917
Query: 751 DL-LSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEV-QKWTNHRVME 808
++ + + + LH L ++ AIQ + ++ P+ P+ T+A ++ +W + E
Sbjct: 918 EIQREIGISNPLHRLKLRLAIQEI-MSLTSPSA---PPTSRTTLAYGDMNHEWIGN---E 970
Query: 809 WLRSVDLAEY 818
WL S+ L +Y
Sbjct: 971 WLPSLGLPQY 980
Score = 35.0 bits (79), Expect = 0.35
Identities = 56/282 (19%), Positives = 114/282 (40%), Gaps = 31/282 (10%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR 162
Q +L + ++++SL Q++ Q A K +L C E+ E+ E+ + +
Sbjct: 65 QGKLHEVGHERDSLQRQLNTALPQEFAALTK--ELNVCREQLLEREEEIAELKAER--NN 120
Query: 163 TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGL--IQEINDLRLKVSEMDSE 220
T L + L+ + L++T V++ + E L ++ + + + E E
Sbjct: 121 TRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRE 180
Query: 221 RLQY--------EKKLKSTKDELASLKEQLEEKES------EVKRLQEKLVC---KMKGE 263
RL+ E++L +T EL LKEQ +K++ ++ QE K +
Sbjct: 181 RLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINHEQENTPSTSGKRSSD 240
Query: 264 G--------VEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNR 315
G ++++ E K+ +E++ +++ + E+ D +DL +
Sbjct: 241 GSLSHEEDLAKVIELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEM 300
Query: 316 YKKMQDTVVLAQGKKGKDGEYEELLNSSSISSLLDAQGFSDL 357
K+Q V A +K E L +++ +A DL
Sbjct: 301 NTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDL 342
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sapiens]
Length = 1202
Score = 159 bits (402), Expect = 1e-38
Identities = 218/920 (23%), Positives = 378/920 (41%), Gaps = 130/920 (14%)
Query: 53 EDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLEND 112
EDL ++E+ E K+ S + + L S +T L + D ++ L + E
Sbjct: 247 EDLAKVIELQEIISKQSRE----QSQMKERLASLSSHVTE--LEEDLDTARKDLIKSEEM 300
Query: 113 KESLVLQVSVLTDQVEAQGEKIRDLE---FCLEEHREKVNATEEMLQQELLSRTSLETQK 169
L V Q E E+I LE + V+ + L+ E+ ++ S+ Q
Sbjct: 301 NTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQT 360
Query: 170 LDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLK 229
D ++ +L+L E K + T + + ++ ++++ + + E++
Sbjct: 361 EDKNRQLQE-RLELA---------EQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHG 410
Query: 230 STKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMK 289
+ ++ L ++ QLEEK E++R +++ KM E + + + K L E N ++++
Sbjct: 411 NIEERLRQMEAQLEEKNQELQRARQRE--KMNEEHNKRLS--DTVDKLLSESN---ERLQ 463
Query: 290 KAVESLMAANEEKD---RKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNSSSIS 346
++ MAA E+K+ R++E ++ L + +D +VL + ++ L +S
Sbjct: 464 LHLKERMAALEDKNSLLREVESAKKQLEETQHDKDQLVLNIEALRAELDHMRLRGASL-- 521
Query: 347 SLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSV----PEEFHTTILQVSIPSLLPATVSM 402
G L P M D ++TS P++ L+ PS +
Sbjct: 522 ----HHGRPHLGSVPDFRFPMADGHTDSYSTSAVLRRPQKGRLAALRDE-PSKVQTLNEQ 576
Query: 403 --ETSEKSKLTPKPETSFEENDGNIILGATV-DTQLC--DKLLTSSLQKSSSLGNLKKET 457
E ++++ + +FE +D ++ G DT L D L S + +L + +E
Sbjct: 577 DWERAQQASVLANVAQAFE-SDADVSDGEDDRDTLLSSVDLLSPSGQADAHTLAMMLQEQ 635
Query: 458 SDGEKETIQKTSEDRAPAESRP--------------------FGTLPPRPPGQDTSMDDN 497
D + I+ E++ E R ++PP P S
Sbjct: 636 LDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPPYPASSLASSSPP 695
Query: 498 PFGT---RKVRSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAETEK----------- 543
G R++ S R ++ T P+ + R ET
Sbjct: 696 GSGRSTPRRIPHSPAREVDRL--GVMTLLPPSREEVRDDKTTIKCETSPPSSPRALRLDR 753
Query: 544 ------ETAEHLDL------AGASSRP--KDSQRNSPFQIPPPSPDSKKKSRGIMKLFGK 589
T H D+ G+ P S NS +P K I +LFGK
Sbjct: 754 LHKGALHTVSHEDIRDIRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGK 813
Query: 590 LRRS-----------QSTTFNPDDMSEPEF---KRGGTRATAGPRLGWSRDLGQSNSDLD 635
+ Q+ D+ S+ K GG +A +L +L +
Sbjct: 814 KEKGRPGQTGKEALGQAGVSETDNSSQDALGLSKLGG-QAEKNRKLQKKHELLEEARRQG 872
Query: 636 MPFAKWTKEQVCNWLMEQGLGS---YLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHR 692
+PFA+W V WL E +G Y+ + + + SG + S ++++E+GI + LHR
Sbjct: 873 LPFAQWDGPTVVVWL-ELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHR 931
Query: 693 KKLQLALQALGSEEETN----------HGKLDFNWV-TRWLDDIGLPQYKTQFDEGRVDG 741
KL+LA+Q + S + +G ++ W+ WL +GLPQY++ F E VD
Sbjct: 932 LKLRLAIQEIMSLTSPSAPPTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDA 991
Query: 742 RMLHYMTVDDLLS-LKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQK 800
RML ++T DL LK+V H S + I LR N++ L R+ +E+ +V
Sbjct: 992 RMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERK-REESQSEIKDVLV 1050
Query: 801 WTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHL 860
W+N RV+ W+ S+ L EYA NL SGVHG L+ L+ F+ +A LL IP T R L
Sbjct: 1051 WSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVL 1110
Query: 861 ATHFN--LLIGAEAQHQKRD 878
FN L++G + + + D
Sbjct: 1111 EREFNNLLVMGTDRRFDEDD 1130
Score = 52.8 bits (125), Expect = 2e-06
Identities = 175/850 (20%), Positives = 327/850 (38%), Gaps = 162/850 (19%)
Query: 60 EMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDV-YQERLARLENDKESLVL 118
E+M E+ + + D + E + T+G +G + ++E LA++ +E +
Sbjct: 202 ELMILKEQNNQKKTLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISK 261
Query: 119 QV---SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAE 175
Q S + +++ + + +LE L+ R+ + +EEM T L+ + MA+
Sbjct: 262 QSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEM-------NTKLQRDVREAMAQ 314
Query: 176 ISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEIND-LRLKVSEMDSERLQYEKKLKSTKDE 234
+++ ++T +EK L + + + ++ND L +++ DS Q E K + ++
Sbjct: 315 KEDMEERITTLEKRYLAAQREATS----VHDLNDKLENEIANKDSMHRQTEDKNRQLQER 370
Query: 235 LASLKEQLEEKESEVKRLQE---------KLVCKMKGEGVEIVDRDENFKKKLKEKNIEV 285
L +++L++ + + L E + K + I +R + +L+EKN E+
Sbjct: 371 LELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQEL 430
Query: 286 QKMKKAVESLMAANEEKDRKIEDLRQCL-------------NRYKKMQDTVVLAQGKKGK 332
Q+ ++ + NEE ++++ D L R ++D L + +
Sbjct: 431 QRARQREK----MNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVESA 486
Query: 333 DGEYEE--------LLNSSSISSLLD---------AQGFSDLEKSPSPTPVMGSPSCDPF 375
+ EE +LN ++ + LD G L P M D +
Sbjct: 487 KKQLEETQHDKDQLVLNIEALRAELDHMRLRGASLHHGRPHLGSVPDFRFPMADGHTDSY 546
Query: 376 NTSV----PEEFHTTILQVSIPSLLPA--TVSMETSEKSKLTPKPETSFEENDGNIILGA 429
+TS P++ L+ PS + E ++++ + +F E+D ++ G
Sbjct: 547 STSAVLRRPQKGRLAALR-DEPSKVQTLNEQDWERAQQASVLANVAQAF-ESDADVSDGE 604
Query: 430 -TVDTQL--CDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESRPFGTLPPR 486
DT L D L S + +L + +E D + I+ E++ E R
Sbjct: 605 DDRDTLLSSVDLLSPSGQADAHTLAMMLQEQLDAINKEIRLIQEEKENTEQR-------- 656
Query: 487 PPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAETEKETA 546
++ S G G S NL R RS S+ A
Sbjct: 657 --------------AEEIESRVGSG-----------SLDNLGRFRSMSS-----IPPYPA 686
Query: 547 EHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLR---RSQSTTF----- 598
L ASS P S R++P +I P SP + G+M L R R TT
Sbjct: 687 SSL----ASSSPPGSGRSTPRRI-PHSPAREVDRLGVMTLLPPSREEVRDDKTTIKCETS 741
Query: 599 ---NPDDMSEPEFKRGG-----------TRATAGPRLGWSRDLGQSNSDLD----MPFAK 640
+P + +G R + G + G + SNS D P K
Sbjct: 742 PPSSPRALRLDRLHKGALHTVSHEDIRDIRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKK 801
Query: 641 WTKEQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIK----HSLHRKKLQ 696
K + ++ G +GK A GQ + + + LG+ + +KLQ
Sbjct: 802 GIKSSIGRLFGKKEKGRPGQTGKE--ALGQAGVSETDNSSQDALGLSKLGGQAEKNRKLQ 859
Query: 697 LALQALGSEEETNHGKLDFNW----VTRWLD-DIGLPQYKTQFDEGRV-DGRMLHYMTVD 750
+ L EE G W V WL+ +G+P + V G ++ ++
Sbjct: 860 KKHELL--EEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDT 917
Query: 751 DL-LSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEV-QKWTNHRVME 808
++ + + + LH L ++ AIQ + ++ P+ P+ T+A ++ +W + E
Sbjct: 918 EIQREIGISNPLHRLKLRLAIQEI-MSLTSPSA---PPTSRTTLAYGDMNHEWIGN---E 970
Query: 809 WLRSVDLAEY 818
WL S+ L +Y
Sbjct: 971 WLPSLGLPQY 980
Score = 35.0 bits (79), Expect = 0.35
Identities = 56/282 (19%), Positives = 114/282 (40%), Gaps = 31/282 (10%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR 162
Q +L + ++++SL Q++ Q A K +L C E+ E+ E+ + +
Sbjct: 65 QGKLHEVGHERDSLQRQLNTALPQEFAALTK--ELNVCREQLLEREEEIAELKAER--NN 120
Query: 163 TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGL--IQEINDLRLKVSEMDSE 220
T L + L+ + L++T V++ + E L ++ + + + E E
Sbjct: 121 TRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRE 180
Query: 221 RLQY--------EKKLKSTKDELASLKEQLEEKES------EVKRLQEKLVC---KMKGE 263
RL+ E++L +T EL LKEQ +K++ ++ QE K +
Sbjct: 181 RLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINHEQENTPSTSGKRSSD 240
Query: 264 G--------VEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNR 315
G ++++ E K+ +E++ +++ + E+ D +DL +
Sbjct: 241 GSLSHEEDLAKVIELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEM 300
Query: 316 YKKMQDTVVLAQGKKGKDGEYEELLNSSSISSLLDAQGFSDL 357
K+Q V A +K E L +++ +A DL
Sbjct: 301 NTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDL 342
>gi|157837985 kazrin isoform E [Homo sapiens]
Length = 775
Score = 158 bits (400), Expect = 2e-38
Identities = 122/355 (34%), Positives = 171/355 (48%), Gaps = 20/355 (5%)
Query: 522 ASAPNLDRKRSASAPTLAETEKETAEHLDLAGASSRPKDSQRNSPF-QIPPPSPDSKKKS 580
ASA DR +S P+ + + L G S P ++P Q D K+K
Sbjct: 323 ASAAEGDR---SSTPSDINSPRHRTHSL-CNGDSPGPVQKNLHNPIVQSLEDLEDQKRKK 378
Query: 581 RGIMKLFGKLRR-----SQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSR--DLGQSNSD 633
+ FG + R Q + +P + + + TR + G + L Q
Sbjct: 379 KKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCSPTRQSLSLSEGEEQMDRLQQVELV 438
Query: 634 LDMPFAKWTKEQVCNWL-MEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHR 692
P + W V WL + + Y+ + + SG+ LL S +DL+ LG+ SLHR
Sbjct: 439 RTTPMSHWKAGTVQAWLEVVMAMPMYVKACTENVKSGKVLLSLSDEDLQLGLGVCSSLHR 498
Query: 693 KKLQLALQALGSEEE----TNHGKLDFNWVTR-WLDDIGLPQYKTQFDEGRVDGRMLHYM 747
+KL+LA++ E + +LD +WV + WL+DIGL QY F VDGRML+ +
Sbjct: 499 RKLRLAIEDYRDAEAGRSLSKAAELDHHWVAKAWLNDIGLSQYSQAFQNHLVDGRMLNSL 558
Query: 748 TVDDLLS-LKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRV 806
DL L V H +SI I++L NF L+ R + T V WTN RV
Sbjct: 559 MKRDLEKHLNVSKKFHQVSILLGIELLYQVNFSREALQERRARCETQNIDPVV-WTNQRV 617
Query: 807 MEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLA 861
++W+R +DL EYA NL SGVHG ++VLEP FN E MA L IP K +LRRHLA
Sbjct: 618 LKWVRDIDLKEYADNLTNSGVHGAVLVLEPTFNAEAMATALGIPSGKHILRRHLA 672
Score = 37.4 bits (85), Expect = 0.071
Identities = 34/147 (23%), Positives = 67/147 (45%), Gaps = 5/147 (3%)
Query: 49 LHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLAR 108
+HL+ ++ +L + +E +G + S E V+ Q + + R
Sbjct: 89 VHLLRQMKEMLAK-DLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQAMKADRKR 147
Query: 109 LENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQ 168
L+ +K LV Q+ L +E++ E++RD E+HR++ + L +E + LE +
Sbjct: 148 LKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKE---KDLLERE 204
Query: 169 KLDLMAEISNLKLKLTAVEKDRLDYED 195
K +L + TA+ + +LD +D
Sbjct: 205 KWELRRQAKEATDHATAL-RSQLDLKD 230
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 155 bits (393), Expect = 1e-37
Identities = 206/878 (23%), Positives = 363/878 (41%), Gaps = 129/878 (14%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQ--QELL 160
+ER+ LE S + + + D + ++ + E L + EK +E L+ ++ L
Sbjct: 337 EERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKL 396
Query: 161 SRTSLETQKL-DLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDS 219
+T + + L ++ AE++ LT E+ + E++ R EG ++E N + + +
Sbjct: 397 QQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREK 456
Query: 220 ERLQYEKKLKSTKDELAS---------LKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDR 270
++ K+L T D L + LKE++ E + +QE + E E +
Sbjct: 457 MNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLE--ESLHD 514
Query: 271 DENFKKKLKEKNIEVQKMKKAVESLMAANEEK---DRKIE---DLRQCLNRYKKMQDTVV 324
E +++++ E+ ++K SL+ + D E + ++ + T V
Sbjct: 515 KERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELRYSVGSLVDSQSDYRTTKV 574
Query: 325 LAQGKKGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTS-----V 379
+ + ++G+ G + + SL D + + T +G S PF + +
Sbjct: 575 IRRPRRGRMGVRRD---EPKVKSLGDHEW--------NRTQQIGVLSSHPFESDTEMSDI 623
Query: 380 PEEFHTTILQVSIPSLLPA------TVSMETSEKSKLTPKPETSFEENDGNIILGATVDT 433
++ TI S+ L P+ T++M E+ K +E + L A
Sbjct: 624 DDDDRETIFS-SMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAE--- 679
Query: 434 QLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPA-ESRPFGTLPPRPPGQDT 492
++ +++ + SL+ +L + TS T + P+ S P L PR P ++
Sbjct: 680 EIENRVASVSLE-GLNLARVHPGTSITASVTASSLASSSPPSGHSTP--KLTPRSPAREM 736
Query: 493 SMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAETEKET-----AE 547
G + S + KI + K S P + T +
Sbjct: 737 DR----MGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRALRMTHTLPSSY 792
Query: 548 HLDLAGASSRPKDSQR------NSPFQIPPPSPDSKKKSRGIMKLFGK---LRRSQSTTF 598
H D + S + + NS +P K I +LFGK R Q F
Sbjct: 793 HNDARSSLSVSLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGF 852
Query: 599 NPDDMSEPE---FKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQGL 655
+ + E + GT+A RL +L + +PFA+W V WL E L
Sbjct: 853 METEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWL-ELWL 911
Query: 656 GS---YLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGS-------- 704
G Y+ + + + SG + S ++++E+GI + LHR KL+LA+Q + S
Sbjct: 912 GMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPP 971
Query: 705 -------------EEETN--------------------------HGKLDFNWV-TRWLDD 724
EE N +G ++ W+ WL
Sbjct: 972 TSRTPSGNVWVTHEEMENLAAPAKTKESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPS 1031
Query: 725 IGLPQYKTQFDEGRVDGRMLHYMTVDDL-LSLKVVSVLHHLSIKRAIQVLRINNFEPNCL 783
+GLPQY++ F E VD RML ++T DL + LK+V H S++ I L+ N++ L
Sbjct: 1032 LGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKEL 1091
Query: 784 -RRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVET 842
RRR + ++ I +V W+N RV+ W++++ L EYA N+ SGVHG L+ L+ F+ +
Sbjct: 1092 ERRREASQHEI--KDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSS 1149
Query: 843 MAQLLNIPPNKTLLRRHLATHFN--LLIGAEAQHQKRD 878
+A LL IP T R+ L +N L +G E + + D
Sbjct: 1150 LALLLQIPTQNTQARQILEREYNNLLALGTERRLDESD 1187
>gi|55769554 protein tyrosine phosphatase, receptor type, f
polypeptide (PTPRF), interacting protein (liprin), alpha
4 [Homo sapiens]
Length = 701
Score = 146 bits (368), Expect = 1e-34
Identities = 141/521 (27%), Positives = 221/521 (42%), Gaps = 84/521 (16%)
Query: 419 EENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESR 478
EE + + ++T++ TS ++ +L L+K S T + P R
Sbjct: 108 EEKESTELRAEEIETRV-----TSGSMEALNLKQLRKRGSIPTSLTALSLASASPPLSGR 162
Query: 479 PFGTLPPRPPGQD-------TSMDDNPFGTRKVRSSFGRGFFK-----IKSNKRTASAPN 526
L R QD T D RK+ S R + IK S+P
Sbjct: 163 STPKLTSRSAAQDLDRMGVMTLPSDLRKHRRKLLSPVSREENREDKATIKCETSPPSSPR 222
Query: 527 LDRKRSASAPTLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKL 586
R P L++ E ++A L S P S NS K I +L
Sbjct: 223 TLRLEKLGHPALSQEEGKSA----LEDQGSNPSSS--NSSQDSLHKGAKRKGIKSSIGRL 276
Query: 587 FGKLRRSQSTTFNPDD------MSEPEFK--------RGGTRATAGPRLGWSRDLGQSNS 632
FGK + + + D +++ EF + GT+A RL L +
Sbjct: 277 FGKKEKGRLIQLSRDGATGHVLLTDSEFSMQEPMVPAKLGTQAEKDRRLKKKHQLLEDAR 336
Query: 633 DLDMPFAKWTKEQVCNWLMEQGLGS---YLNSGKHWIASGQTLLQASQQDLEKELGIKHS 689
MPFA+W V +WL E +G Y+ + + + SG + S ++++E+GI ++
Sbjct: 337 RKGMPFAQWDGPTVVSWL-ELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNA 395
Query: 690 LHRKKLQLALQALGS----------------------EEET------------------N 709
LHR KL+LA+Q + S E ET
Sbjct: 396 LHRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEMETLETSTKTDSEEGSWAQTLA 455
Query: 710 HGKLDFNWV-TRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDL-LSLKVVSVLHHLSIK 767
+G ++ W+ WL +GLPQY++ F E VD RML ++T DL + LK+V H S++
Sbjct: 456 YGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQ 515
Query: 768 RAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGV 827
I L+ N++ L +R +E+ +V WTN +V+ W++S+ L +YA NL SGV
Sbjct: 516 YGIMCLKRLNYDRKELEKR-REESQHEIKDVLVWTNDQVVHWVQSIGLRDYAGNLHESGV 574
Query: 828 HGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLI 868
HG L+ L+ F+ T+A +L IP T R+ + FN L+
Sbjct: 575 HGALLALDENFDHNTLALILQIPTQNTQARQVMEREFNNLL 615
>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
Length = 1194
Score = 143 bits (360), Expect = 9e-34
Identities = 201/857 (23%), Positives = 338/857 (39%), Gaps = 146/857 (17%)
Query: 128 EAQGEKIRDLEFCL---EEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLK-LKL 183
EA + RDL+ L E+ E++ E+ TSL L E+++ + L
Sbjct: 282 EANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYR 341
Query: 184 TAVEKDRL------DYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELAS 237
+ EK R D + K + T + + ++ ++++ + + E++ + ++ L
Sbjct: 342 QSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQ 401
Query: 238 LKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMA 297
L+ QLEEK E++R +++ KM + + + E K L E N ++++ ++ M
Sbjct: 402 LEAQLEEKNQELQRARQRE--KMNDDHNKRLS--ETVDKLLSESN---ERLQLHLKERMG 454
Query: 298 ANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEEL----LNSSSISSLLDAQG 353
A EEK+ E++ KK+QD ++L + + + E ++ L SS +
Sbjct: 455 ALEEKNSLSEEIANM----KKLQDELLLNKEQLLAEMERMQMEIDQLRGRPPSSYSRSLP 510
Query: 354 FSDLEKSPSPTPVMGSPS-CDPFN------------TSVPEE----FHTTILQVSIPSLL 396
S LE S P + S + DP+ + V EE + + SIP
Sbjct: 511 GSALELRYSQAPTLPSGAHLDPYVAGSGRAGKRGRWSGVKEEPSKDWERSAPAGSIPPPF 570
Query: 397 PATVSMETSEKSK-------LTPKPETSFE-------------ENDGNIILGATVDTQLC 436
P + E+++ L+P + + + +I T+
Sbjct: 571 PGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQR 630
Query: 437 DKLLTSSLQKSS--SLGNLKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSM 494
+ L S + S SLG + S T + P+ L P P ++ +
Sbjct: 631 AEELESRVSSSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTD 690
Query: 495 DDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAETEKETAEHLDLAGA 554
N + + G G P + P A E+ T AG+
Sbjct: 691 KANHVPKEEAGAPRGEG-------------PAIPGDTPPPTPRSARLERMTQALALQAGS 737
Query: 555 ---SSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTTFNPDDMSEPEFKRG 611
P+ S+ P S K S G +LFGK + + D S
Sbjct: 738 LEDGGPPRGSEGTPDSLHKAPKKKSIKSSIG--RLFGKKEKGRMGPPGRDSSSLAGTPSD 795
Query: 612 GTRATAGPRLGWSRDLGQSNSDL---------------DMPFAKWTKEQVCNWLMEQGLG 656
T AT LG ++ G + D +PFA W V +WL E +G
Sbjct: 796 ETLAT--DPLGLAKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWL-ELWVG 852
Query: 657 S---YLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGS--------- 704
Y+ + + + SG + S ++++E+GI + LHR KL+LA+Q + S
Sbjct: 853 MPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPAS 912
Query: 705 -------------------------------EEETNHGKLDFNWVTR-WLDDIGLPQYKT 732
E+ +G ++ WV WL +GLPQY++
Sbjct: 913 SRTSTGNVWMTHEEMESLTATTKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRS 972
Query: 733 QFDEGRVDGRMLHYMTVDDLLS-LKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDEN 791
F E VD RML ++ +L LK+V H +S+ I L+ N++ L RR +
Sbjct: 973 YFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQ 1032
Query: 792 TIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPP 851
T +V W+N RVM W+ + L E+A NL SGVHG L+ L+ F+ +A LL IP
Sbjct: 1033 TQI-RDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPT 1091
Query: 852 NKTLLRRHLATHFNLLI 868
R+ L F+ LI
Sbjct: 1092 QNAQARQLLEKEFSNLI 1108
Score = 32.7 bits (73), Expect = 1.8
Identities = 41/210 (19%), Positives = 93/210 (44%), Gaps = 22/210 (10%)
Query: 152 EEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKF----RDTEGLIQEI 207
EE L+++ L + L ++S L+ +L ++ E+ RD + + +
Sbjct: 239 EEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQR 298
Query: 208 NDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEI 267
D+ +++ ++ L +++ S D L+ +L KES ++ +EK ++
Sbjct: 299 EDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEK--------SRQL 350
Query: 268 VDRDENFKKKLKE--------KNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKM 319
+ ++ K+KL++ IE Q + + V +L A E E LRQ + ++
Sbjct: 351 AEWLDDAKQKLQQTLQKAETLPEIEAQ-LAQRVAALNKAEERHGNFEERLRQLEAQLEEK 409
Query: 320 QDTVVLAQGKKGKDGEYEELLNSSSISSLL 349
+ A+ ++ + ++ + L S ++ LL
Sbjct: 410 NQELQRARQREKMNDDHNKRL-SETVDKLL 438
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 69.7 bits (169), Expect = 1e-11
Identities = 93/435 (21%), Positives = 189/435 (43%), Gaps = 55/435 (12%)
Query: 1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE 60
+ S A A EQ++G++A + AL S L AL ++ +
Sbjct: 313 LQDQVSIQSADAQEQVEGLLAENNALRTS----------------LAALEQIQTAKTQEL 356
Query: 61 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGN---GDVYQERLARLENDKESLV 117
M ++ GL ++ AE Q N L + E+L + +KE L
Sbjct: 357 NMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLT 416
Query: 118 LQVSVLTDQVEAQGEKIRDLEF-CLEE---HREKVNATEEMLQQELLS-RTSLETQKLDL 172
++ E + + +L L+E H+E++ A ++E+L R E + +L
Sbjct: 417 QELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYERELREL 476
Query: 173 MAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTK 232
+ + +L ++ + + R+ E L Q + +L+ +V MD + +E++LK +
Sbjct: 477 HEDKKRQEEELRGQIREE---KARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAE 533
Query: 233 DELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEV------- 285
+ SL++Q +E+E +K+ +E+ ++KG+ E+ D + ++ +E++ +
Sbjct: 534 E---SLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLK 590
Query: 286 QKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNSSSI 345
Q++K V+ ++ ++DL++ L+ +K D + +++L +S
Sbjct: 591 QEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKL---------QERLQDILTNSKS 641
Query: 346 SSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETS 405
S L+ S++ SPS T S S F+ + IL+ S +PA S+ +S
Sbjct: 642 RSGLEELVLSEM-NSPSRTQTGDSSSISSFS-------YREILREKESSAVPAR-SLSSS 692
Query: 406 EKSKLTPKPETSFEE 420
+++ E S EE
Sbjct: 693 PQAQPPRPAELSDEE 707
Score = 32.7 bits (73), Expect = 1.8
Identities = 54/265 (20%), Positives = 105/265 (39%), Gaps = 35/265 (13%)
Query: 223 QYEKKLKSTKDELASLKEQLE----EKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKL 278
+ E K + K+E L EQL+ K++E RLQE+L + ++ + E+F +
Sbjct: 191 EVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSE----KLKKKQESFCRLQ 246
Query: 279 KEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTV-----VLAQGKKGKD 333
EK + +E L + RK D + L R +K+Q + LA+ + +
Sbjct: 247 TEKETLFNDSRNKIEEL------QQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQ 300
Query: 334 GEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIP 393
G E L +++++ +L D + ++ + + + E+ T Q +
Sbjct: 301 G--ERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQ-ELN 357
Query: 394 SLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNL 453
L T + + + + +++D N L SL+ +S L
Sbjct: 358 MLREQTTGLAAELQQQQAEYEDLMGQKDDLN-------------SQLQESLRANSRLLEQ 404
Query: 454 KKETSDGEKETIQKTSEDRAPAESR 478
+E +++ Q+ E R AE R
Sbjct: 405 LQEIGQEKEQLTQELQEARKSAEKR 429
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 68.6 bits (166), Expect = 3e-11
Identities = 70/297 (23%), Positives = 139/297 (46%), Gaps = 46/297 (15%)
Query: 102 YQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHR-------EKVNATEEM 154
Y E ++ + E L ++ L + ++ + ++I L+ LEE+ E +N ++
Sbjct: 150 YIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQL 209
Query: 155 LQQELLSRTSLETQKLD-LMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLK 213
L++E + + + L AE+ NLK K +++R + K + L+Q+ +L
Sbjct: 210 LEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSS 269
Query: 214 V--------SEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGV 265
+ EM E+ +E++LK T DEL L+++ E+ E VK+L+E+ K + E +
Sbjct: 270 LHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEE--AKSRAEEL 327
Query: 266 EIVDRDENFKKKLKEKNIEVQKMKKA-VESLMAANEEKD---RKIEDLRQCLNRYKKMQD 321
++++ +KLK K E++K A ++ + E+ D + +ED+ YK +
Sbjct: 328 KLLE------EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTA 381
Query: 322 TVV--------------LAQGKKGKDGEYEELLNSSS----ISSLLDAQGFSDLEKS 360
+ + GK +D +++ L SS + LLD Q S L+++
Sbjct: 382 SEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKET 438
Score = 53.9 bits (128), Expect = 7e-07
Identities = 55/237 (23%), Positives = 109/237 (45%), Gaps = 17/237 (7%)
Query: 95 LPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEM 154
L N +++L L E L + S +Q + +I LE ++ + M
Sbjct: 43 LSANNATLEKQLIELTRTNELLKSKFSENGNQ---KNLRILSLELMKLRNKRETKMRGMM 99
Query: 155 LQQELLSRTSLETQKL--DLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRL 212
+QE + TQ+ + +I+ L+ KL ++EK+++D + +TE L++ I ++
Sbjct: 100 AKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKS---ETEKLLEYIEEISC 156
Query: 213 KVSEMDSERL---QYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCK---MKGEGVE 266
+++ +L Q E+ LK DE+ SLK+ LEE + + E L K ++ E +
Sbjct: 157 ASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKED 216
Query: 267 IVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTV 323
V+R+ + L N E+Q +K+ E+ +K + L + K++ ++
Sbjct: 217 HVNRNREHNENL---NAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSL 270
Score = 52.4 bits (124), Expect = 2e-06
Identities = 68/247 (27%), Positives = 115/247 (46%), Gaps = 37/247 (14%)
Query: 116 LVLQVSVLTDQVEAQGEKIRDLEFCLEEH--------REKV-----NATEEMLQQELLSR 162
+ L + VL + AQ +I+DLE LE+ REK NAT E EL
Sbjct: 1 MTLLIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRT 60
Query: 163 TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERL 222
L K NL++ + K R E K R QE +++L+V++ E
Sbjct: 61 NELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAK-QEGMEMKLQVTQRSLEES 119
Query: 223 QYEKKLKSTKDELASL-KEQLEEKESEVKRLQ--EKLVC---KMKGEGVEIVDRDENFKK 276
Q K+ + +L S+ KE+++EK K L+ E++ C +++ ++I +EN
Sbjct: 120 Q--GKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEEN--- 174
Query: 277 KLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLR-QCLNRYKKMQDTVVLAQGKKGKDGE 335
LKEKN E+ +K+++E + +++EDL +C K+ +D V ++ E
Sbjct: 175 -LKEKNDEILSLKQSLEENIVI---LSKQVEDLNVKCQLLEKEKEDHV-------NRNRE 223
Query: 336 YEELLNS 342
+ E LN+
Sbjct: 224 HNENLNA 230
Score = 39.7 bits (91), Expect = 0.014
Identities = 55/289 (19%), Positives = 127/289 (43%), Gaps = 34/289 (11%)
Query: 50 HLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARL 109
+L +++ L + +++E + Q + ++L++ Q + + L +QE + +
Sbjct: 227 NLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQ--QEKELSSSLHQKLCSFQEEMVKE 284
Query: 110 ENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK 169
+N E + Q D+++ + E+ L LEE K A E L +E L E +K
Sbjct: 285 KNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEA-KSRAEELKLLEEKLKGKEAELEK 343
Query: 170 LDLMAEISNLKL--KLTAVEKDRLDYEDKFRDTEGLI-QEINDLRLKVSEMDSERLQYEK 226
+ L L K ++ + D +F + L EI DL+L+ S + + + K
Sbjct: 344 SSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGK 403
Query: 227 KLKSTKDELASLKEQLEE--------------KESEVKRLQEKLVCKMKGEGVEIVDRDE 272
+ + ++ + + +E KE+E+K + + K+ ++ ++E
Sbjct: 404 NAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEE 463
Query: 273 NFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQD 321
+F+K+L++ ++ +KA EK+ +L + +N+++ + +
Sbjct: 464 DFRKQLED-----EEGRKA---------EKENTTAELTEEINKWRLLYE 498
Score = 35.0 bits (79), Expect = 0.35
Identities = 34/161 (21%), Positives = 71/161 (44%), Gaps = 18/161 (11%)
Query: 49 LHLVEDLRGLLEMMETD------EKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVY 102
L + DL+ L+ E D ++EG + + ++TAE E + ++ L +
Sbjct: 448 LQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPF 507
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR 162
Q +L E +K++L+ + +Q+ KIRD L H+ L+Q++
Sbjct: 508 QLQLDAFEVEKQALLNEHGAAQEQL----NKIRDSYAKLLGHQN--------LKQKIKHV 555
Query: 163 TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGL 203
L+ + L +E+S L+ +L ++ +++ G+
Sbjct: 556 VKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGI 596
Score = 30.4 bits (67), Expect = 8.7
Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 15/151 (9%)
Query: 115 SLVLQVSVLTDQVEAQGEKIR-DLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLM 173
S + +++ L +Q++ Q E R LE EK N T E+ ++ +++ L ++L
Sbjct: 446 SFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEE--INKWRLLYEELYNK 503
Query: 174 AEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQE-INDLRLKVSEMDSERLQYEKKLKSTK 232
+ L+L VEK L E G QE +N +R + +L + LK
Sbjct: 504 TKPFQLQLDAFEVEKQALLNE------HGAAQEQLNKIRDSYA-----KLLGHQNLKQKI 552
Query: 233 DELASLKEQLEEKESEVKRLQEKLVCKMKGE 263
+ LK++ + +SEV +L+ +L K + E
Sbjct: 553 KHVVKLKDENSQLKSEVSKLRCQLAKKKQSE 583
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 68.6 bits (166), Expect = 3e-11
Identities = 70/297 (23%), Positives = 139/297 (46%), Gaps = 46/297 (15%)
Query: 102 YQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHR-------EKVNATEEM 154
Y E ++ + E L ++ L + ++ + ++I L+ LEE+ E +N ++
Sbjct: 237 YIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQL 296
Query: 155 LQQELLSRTSLETQKLD-LMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLK 213
L++E + + + L AE+ NLK K +++R + K + L+Q+ +L
Sbjct: 297 LEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSS 356
Query: 214 V--------SEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGV 265
+ EM E+ +E++LK T DEL L+++ E+ E VK+L+E+ K + E +
Sbjct: 357 LHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEE--AKSRAEEL 414
Query: 266 EIVDRDENFKKKLKEKNIEVQKMKKA-VESLMAANEEKD---RKIEDLRQCLNRYKKMQD 321
++++ +KLK K E++K A ++ + E+ D + +ED+ YK +
Sbjct: 415 KLLE------EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTA 468
Query: 322 TVV--------------LAQGKKGKDGEYEELLNSSS----ISSLLDAQGFSDLEKS 360
+ + GK +D +++ L SS + LLD Q S L+++
Sbjct: 469 SEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKET 525
Score = 55.5 bits (132), Expect = 3e-07
Identities = 71/255 (27%), Positives = 121/255 (47%), Gaps = 39/255 (15%)
Query: 110 ENDKESLVLQ--VSVLTDQVEAQGEKIRDLEFCLEEH--------REKV-----NATEEM 154
+NDK+ +L+ + VL + AQ +I+DLE LE+ REK NAT E
Sbjct: 80 KNDKDLKILEKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEK 139
Query: 155 LQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKV 214
EL L K NL++ + K R E K R QE +++L+V
Sbjct: 140 QLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAK-QEGMEMKLQV 198
Query: 215 SEMDSERLQYEKKLKSTKDELASL-KEQLEEKESEVKRLQ--EKLVC---KMKGEGVEIV 268
++ E Q K+ + +L S+ KE+++EK K L+ E++ C +++ ++I
Sbjct: 199 TQRSLEESQ--GKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIA 256
Query: 269 DRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLR-QCLNRYKKMQDTVVLAQ 327
+EN LKEKN E+ +K+++E + +++EDL +C K+ +D V
Sbjct: 257 QLEEN----LKEKNDEILSLKQSLEENIVI---LSKQVEDLNVKCQLLEKEKEDHV---- 305
Query: 328 GKKGKDGEYEELLNS 342
++ E+ E LN+
Sbjct: 306 ---NRNREHNENLNA 317
Score = 53.9 bits (128), Expect = 7e-07
Identities = 55/237 (23%), Positives = 109/237 (45%), Gaps = 17/237 (7%)
Query: 95 LPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEM 154
L N +++L L E L + S +Q + +I LE ++ + M
Sbjct: 130 LSANNATLEKQLIELTRTNELLKSKFSENGNQ---KNLRILSLELMKLRNKRETKMRGMM 186
Query: 155 LQQELLSRTSLETQKL--DLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRL 212
+QE + TQ+ + +I+ L+ KL ++EK+++D + +TE L++ I ++
Sbjct: 187 AKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKS---ETEKLLEYIEEISC 243
Query: 213 KVSEMDSERL---QYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCK---MKGEGVE 266
+++ +L Q E+ LK DE+ SLK+ LEE + + E L K ++ E +
Sbjct: 244 ASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKED 303
Query: 267 IVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTV 323
V+R+ + L N E+Q +K+ E+ +K + L + K++ ++
Sbjct: 304 HVNRNREHNENL---NAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSL 357
Score = 39.7 bits (91), Expect = 0.014
Identities = 55/289 (19%), Positives = 127/289 (43%), Gaps = 34/289 (11%)
Query: 50 HLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARL 109
+L +++ L + +++E + Q + ++L++ Q + + L +QE + +
Sbjct: 314 NLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQ--QEKELSSSLHQKLCSFQEEMVKE 371
Query: 110 ENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK 169
+N E + Q D+++ + E+ L LEE K A E L +E L E +K
Sbjct: 372 KNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEA-KSRAEELKLLEEKLKGKEAELEK 430
Query: 170 LDLMAEISNLKL--KLTAVEKDRLDYEDKFRDTEGLI-QEINDLRLKVSEMDSERLQYEK 226
+ L L K ++ + D +F + L EI DL+L+ S + + + K
Sbjct: 431 SSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGK 490
Query: 227 KLKSTKDELASLKEQLEE--------------KESEVKRLQEKLVCKMKGEGVEIVDRDE 272
+ + ++ + + +E KE+E+K + + K+ ++ ++E
Sbjct: 491 NAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEE 550
Query: 273 NFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQD 321
+F+K+L++ ++ +KA EK+ +L + +N+++ + +
Sbjct: 551 DFRKQLED-----EEGRKA---------EKENTTAELTEEINKWRLLYE 585
Score = 35.0 bits (79), Expect = 0.35
Identities = 34/161 (21%), Positives = 71/161 (44%), Gaps = 18/161 (11%)
Query: 49 LHLVEDLRGLLEMMETD------EKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVY 102
L + DL+ L+ E D ++EG + + ++TAE E + ++ L +
Sbjct: 535 LQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPF 594
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR 162
Q +L E +K++L+ + +Q+ KIRD L H+ L+Q++
Sbjct: 595 QLQLDAFEVEKQALLNEHGAAQEQL----NKIRDSYAKLLGHQN--------LKQKIKHV 642
Query: 163 TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGL 203
L+ + L +E+S L+ +L ++ +++ G+
Sbjct: 643 VKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGI 683
Score = 30.4 bits (67), Expect = 8.7
Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 15/151 (9%)
Query: 115 SLVLQVSVLTDQVEAQGEKIR-DLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLM 173
S + +++ L +Q++ Q E R LE EK N T E+ ++ +++ L ++L
Sbjct: 533 SFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEE--INKWRLLYEELYNK 590
Query: 174 AEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQE-INDLRLKVSEMDSERLQYEKKLKSTK 232
+ L+L VEK L E G QE +N +R + +L + LK
Sbjct: 591 TKPFQLQLDAFEVEKQALLNE------HGAAQEQLNKIRDSYA-----KLLGHQNLKQKI 639
Query: 233 DELASLKEQLEEKESEVKRLQEKLVCKMKGE 263
+ LK++ + +SEV +L+ +L K + E
Sbjct: 640 KHVVKLKDENSQLKSEVSKLRCQLAKKKQSE 670
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 68.6 bits (166), Expect = 3e-11
Identities = 70/297 (23%), Positives = 139/297 (46%), Gaps = 46/297 (15%)
Query: 102 YQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHR-------EKVNATEEM 154
Y E ++ + E L ++ L + ++ + ++I L+ LEE+ E +N ++
Sbjct: 221 YIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQL 280
Query: 155 LQQELLSRTSLETQKLD-LMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLK 213
L++E + + + L AE+ NLK K +++R + K + L+Q+ +L
Sbjct: 281 LEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSS 340
Query: 214 V--------SEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGV 265
+ EM E+ +E++LK T DEL L+++ E+ E VK+L+E+ K + E +
Sbjct: 341 LHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEE--AKSRAEEL 398
Query: 266 EIVDRDENFKKKLKEKNIEVQKMKKA-VESLMAANEEKD---RKIEDLRQCLNRYKKMQD 321
++++ +KLK K E++K A ++ + E+ D + +ED+ YK +
Sbjct: 399 KLLE------EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTA 452
Query: 322 TVV--------------LAQGKKGKDGEYEELLNSSS----ISSLLDAQGFSDLEKS 360
+ + GK +D +++ L SS + LLD Q S L+++
Sbjct: 453 SEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKET 509
Score = 53.9 bits (128), Expect = 7e-07
Identities = 55/237 (23%), Positives = 109/237 (45%), Gaps = 17/237 (7%)
Query: 95 LPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEM 154
L N +++L L E L + S +Q + +I LE ++ + M
Sbjct: 114 LSANNATLEKQLIELTRTNELLKSKFSENGNQ---KNLRILSLELMKLRNKRETKMRGMM 170
Query: 155 LQQELLSRTSLETQKL--DLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRL 212
+QE + TQ+ + +I+ L+ KL ++EK+++D + +TE L++ I ++
Sbjct: 171 AKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKS---ETEKLLEYIEEISC 227
Query: 213 KVSEMDSERL---QYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCK---MKGEGVE 266
+++ +L Q E+ LK DE+ SLK+ LEE + + E L K ++ E +
Sbjct: 228 ASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKED 287
Query: 267 IVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTV 323
V+R+ + L N E+Q +K+ E+ +K + L + K++ ++
Sbjct: 288 HVNRNREHNENL---NAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSL 341
Score = 51.2 bits (121), Expect = 5e-06
Identities = 67/244 (27%), Positives = 114/244 (46%), Gaps = 37/244 (15%)
Query: 119 QVSVLTDQVEAQGEKIRDLEFCLEEH--------REKV-----NATEEMLQQELLSRTSL 165
++ VL + AQ +I+DLE LE+ REK NAT E EL L
Sbjct: 75 KIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNEL 134
Query: 166 ETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYE 225
K NL++ + K R E K R QE +++L+V++ E Q
Sbjct: 135 LKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAK-QEGMEMKLQVTQRSLEESQ-- 191
Query: 226 KKLKSTKDELASL-KEQLEEKESEVKRLQ--EKLVC---KMKGEGVEIVDRDENFKKKLK 279
K+ + +L S+ KE+++EK K L+ E++ C +++ ++I +EN LK
Sbjct: 192 GKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEEN----LK 247
Query: 280 EKNIEVQKMKKAVESLMAANEEKDRKIEDLR-QCLNRYKKMQDTVVLAQGKKGKDGEYEE 338
EKN E+ +K+++E + +++EDL +C K+ +D V ++ E+ E
Sbjct: 248 EKNDEILSLKQSLEENIVI---LSKQVEDLNVKCQLLEKEKEDHV-------NRNREHNE 297
Query: 339 LLNS 342
LN+
Sbjct: 298 NLNA 301
Score = 39.7 bits (91), Expect = 0.014
Identities = 55/289 (19%), Positives = 127/289 (43%), Gaps = 34/289 (11%)
Query: 50 HLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARL 109
+L +++ L + +++E + Q + ++L++ Q + + L +QE + +
Sbjct: 298 NLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQ--QEKELSSSLHQKLCSFQEEMVKE 355
Query: 110 ENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK 169
+N E + Q D+++ + E+ L LEE K A E L +E L E +K
Sbjct: 356 KNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEA-KSRAEELKLLEEKLKGKEAELEK 414
Query: 170 LDLMAEISNLKL--KLTAVEKDRLDYEDKFRDTEGLI-QEINDLRLKVSEMDSERLQYEK 226
+ L L K ++ + D +F + L EI DL+L+ S + + + K
Sbjct: 415 SSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGK 474
Query: 227 KLKSTKDELASLKEQLEE--------------KESEVKRLQEKLVCKMKGEGVEIVDRDE 272
+ + ++ + + +E KE+E+K + + K+ ++ ++E
Sbjct: 475 NAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEE 534
Query: 273 NFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQD 321
+F+K+L++ ++ +KA EK+ +L + +N+++ + +
Sbjct: 535 DFRKQLED-----EEGRKA---------EKENTTAELTEEINKWRLLYE 569
Score = 35.0 bits (79), Expect = 0.35
Identities = 34/161 (21%), Positives = 71/161 (44%), Gaps = 18/161 (11%)
Query: 49 LHLVEDLRGLLEMMETD------EKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVY 102
L + DL+ L+ E D ++EG + + ++TAE E + ++ L +
Sbjct: 519 LQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPF 578
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR 162
Q +L E +K++L+ + +Q+ KIRD L H+ L+Q++
Sbjct: 579 QLQLDAFEVEKQALLNEHGAAQEQL----NKIRDSYAKLLGHQN--------LKQKIKHV 626
Query: 163 TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGL 203
L+ + L +E+S L+ +L ++ +++ G+
Sbjct: 627 VKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGI 667
Score = 30.4 bits (67), Expect = 8.7
Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 15/151 (9%)
Query: 115 SLVLQVSVLTDQVEAQGEKIR-DLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLM 173
S + +++ L +Q++ Q E R LE EK N T E+ ++ +++ L ++L
Sbjct: 517 SFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEE--INKWRLLYEELYNK 574
Query: 174 AEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQE-INDLRLKVSEMDSERLQYEKKLKSTK 232
+ L+L VEK L E G QE +N +R + +L + LK
Sbjct: 575 TKPFQLQLDAFEVEKQALLNE------HGAAQEQLNKIRDSYA-----KLLGHQNLKQKI 623
Query: 233 DELASLKEQLEEKESEVKRLQEKLVCKMKGE 263
+ LK++ + +SEV +L+ +L K + E
Sbjct: 624 KHVVKLKDENSQLKSEVSKLRCQLAKKKQSE 654
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 68.6 bits (166), Expect = 3e-11
Identities = 70/297 (23%), Positives = 139/297 (46%), Gaps = 46/297 (15%)
Query: 102 YQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHR-------EKVNATEEM 154
Y E ++ + E L ++ L + ++ + ++I L+ LEE+ E +N ++
Sbjct: 236 YIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQL 295
Query: 155 LQQELLSRTSLETQKLD-LMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLK 213
L++E + + + L AE+ NLK K +++R + K + L+Q+ +L
Sbjct: 296 LEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSS 355
Query: 214 V--------SEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGV 265
+ EM E+ +E++LK T DEL L+++ E+ E VK+L+E+ K + E +
Sbjct: 356 LHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEE--AKSRAEEL 413
Query: 266 EIVDRDENFKKKLKEKNIEVQKMKKA-VESLMAANEEKD---RKIEDLRQCLNRYKKMQD 321
++++ +KLK K E++K A ++ + E+ D + +ED+ YK +
Sbjct: 414 KLLE------EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTA 467
Query: 322 TVV--------------LAQGKKGKDGEYEELLNSSS----ISSLLDAQGFSDLEKS 360
+ + GK +D +++ L SS + LLD Q S L+++
Sbjct: 468 SEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKET 524
Score = 55.5 bits (132), Expect = 3e-07
Identities = 71/255 (27%), Positives = 121/255 (47%), Gaps = 39/255 (15%)
Query: 110 ENDKESLVLQ--VSVLTDQVEAQGEKIRDLEFCLEEH--------REKV-----NATEEM 154
+NDK+ +L+ + VL + AQ +I+DLE LE+ REK NAT E
Sbjct: 79 KNDKDLKILEKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEK 138
Query: 155 LQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKV 214
EL L K NL++ + K R E K R QE +++L+V
Sbjct: 139 QLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAK-QEGMEMKLQV 197
Query: 215 SEMDSERLQYEKKLKSTKDELASL-KEQLEEKESEVKRLQ--EKLVC---KMKGEGVEIV 268
++ E Q K+ + +L S+ KE+++EK K L+ E++ C +++ ++I
Sbjct: 198 TQRSLEESQ--GKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIA 255
Query: 269 DRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLR-QCLNRYKKMQDTVVLAQ 327
+EN LKEKN E+ +K+++E + +++EDL +C K+ +D V
Sbjct: 256 QLEEN----LKEKNDEILSLKQSLEENIVI---LSKQVEDLNVKCQLLEKEKEDHV---- 304
Query: 328 GKKGKDGEYEELLNS 342
++ E+ E LN+
Sbjct: 305 ---NRNREHNENLNA 316
Score = 53.9 bits (128), Expect = 7e-07
Identities = 55/237 (23%), Positives = 109/237 (45%), Gaps = 17/237 (7%)
Query: 95 LPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEM 154
L N +++L L E L + S +Q + +I LE ++ + M
Sbjct: 129 LSANNATLEKQLIELTRTNELLKSKFSENGNQ---KNLRILSLELMKLRNKRETKMRGMM 185
Query: 155 LQQELLSRTSLETQKL--DLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRL 212
+QE + TQ+ + +I+ L+ KL ++EK+++D + +TE L++ I ++
Sbjct: 186 AKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKS---ETEKLLEYIEEISC 242
Query: 213 KVSEMDSERL---QYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCK---MKGEGVE 266
+++ +L Q E+ LK DE+ SLK+ LEE + + E L K ++ E +
Sbjct: 243 ASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKED 302
Query: 267 IVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTV 323
V+R+ + L N E+Q +K+ E+ +K + L + K++ ++
Sbjct: 303 HVNRNREHNENL---NAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSL 356
Score = 39.7 bits (91), Expect = 0.014
Identities = 55/289 (19%), Positives = 127/289 (43%), Gaps = 34/289 (11%)
Query: 50 HLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARL 109
+L +++ L + +++E + Q + ++L++ Q + + L +QE + +
Sbjct: 313 NLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQ--QEKELSSSLHQKLCSFQEEMVKE 370
Query: 110 ENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK 169
+N E + Q D+++ + E+ L LEE K A E L +E L E +K
Sbjct: 371 KNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEA-KSRAEELKLLEEKLKGKEAELEK 429
Query: 170 LDLMAEISNLKL--KLTAVEKDRLDYEDKFRDTEGLI-QEINDLRLKVSEMDSERLQYEK 226
+ L L K ++ + D +F + L EI DL+L+ S + + + K
Sbjct: 430 SSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGK 489
Query: 227 KLKSTKDELASLKEQLEE--------------KESEVKRLQEKLVCKMKGEGVEIVDRDE 272
+ + ++ + + +E KE+E+K + + K+ ++ ++E
Sbjct: 490 NAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEE 549
Query: 273 NFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQD 321
+F+K+L++ ++ +KA EK+ +L + +N+++ + +
Sbjct: 550 DFRKQLED-----EEGRKA---------EKENTTAELTEEINKWRLLYE 584
Score = 35.0 bits (79), Expect = 0.35
Identities = 34/161 (21%), Positives = 71/161 (44%), Gaps = 18/161 (11%)
Query: 49 LHLVEDLRGLLEMMETD------EKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVY 102
L + DL+ L+ E D ++EG + + ++TAE E + ++ L +
Sbjct: 534 LQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPF 593
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR 162
Q +L E +K++L+ + +Q+ KIRD L H+ L+Q++
Sbjct: 594 QLQLDAFEVEKQALLNEHGAAQEQL----NKIRDSYAKLLGHQN--------LKQKIKHV 641
Query: 163 TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGL 203
L+ + L +E+S L+ +L ++ +++ G+
Sbjct: 642 VKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGI 682
Score = 30.4 bits (67), Expect = 8.7
Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 15/151 (9%)
Query: 115 SLVLQVSVLTDQVEAQGEKIR-DLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLM 173
S + +++ L +Q++ Q E R LE EK N T E+ ++ +++ L ++L
Sbjct: 532 SFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEE--INKWRLLYEELYNK 589
Query: 174 AEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQE-INDLRLKVSEMDSERLQYEKKLKSTK 232
+ L+L VEK L E G QE +N +R + +L + LK
Sbjct: 590 TKPFQLQLDAFEVEKQALLNE------HGAAQEQLNKIRDSYA-----KLLGHQNLKQKI 638
Query: 233 DELASLKEQLEEKESEVKRLQEKLVCKMKGE 263
+ LK++ + +SEV +L+ +L K + E
Sbjct: 639 KHVVKLKDENSQLKSEVSKLRCQLAKKKQSE 669
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 68.2 bits (165), Expect = 4e-11
Identities = 76/340 (22%), Positives = 146/340 (42%), Gaps = 70/340 (20%)
Query: 51 LVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLE 110
+ + + L E +E +E + Q+ TAE ++ L+ ++ V ++ +L
Sbjct: 948 MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEIL---------VMDDQNNKLS 998
Query: 111 NDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK- 169
+++ L ++S LT + + EK ++L +H ++ E L++E SR LE K
Sbjct: 999 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1058
Query: 170 -------------LDLMAEISNLKLKLTAVEKD------RLDYE--------DKFRDTEG 202
DL A+I+ LK++L E++ RLD E K R+ EG
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
Query: 203 LIQEINDLRLKVSEMDSERLQYEKKLKSTKD---ELASLKEQLEE--------------K 245
I ++ + ++DSER K K +D EL +LK +LE+ +
Sbjct: 1119 HISDLQE------DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1172
Query: 246 ESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRK 305
E EV L++ L + + ++ + + + ++E ++++ K+A +L + +++
Sbjct: 1173 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Query: 306 IEDL----------RQCLNRYKKMQDTVVLAQGKKGKDGE 335
DL +Q + KK + V K DGE
Sbjct: 1233 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE 1272
Score = 56.6 bits (135), Expect = 1e-07
Identities = 57/219 (26%), Positives = 114/219 (52%), Gaps = 12/219 (5%)
Query: 126 QVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTA 185
QV Q E+++ E L++ +E+ E L+ EL + S T++ +L+ E + +L A
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQEQLQAETELYA 904
Query: 186 -VEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEE 244
E+ R+ K ++ E ++ E+ + RL+ E ++LQ E+K + ++ L+EQLEE
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEM-EARLEEEEDRGQQLQAERKKMA--QQMLDLEEQLEE 961
Query: 245 KESEVKRLQEKLV---CKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEE 301
+E+ ++LQ + V K+K EI+ D+ K KE+ + +++ + L E
Sbjct: 962 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL----LEERISDLTTNLAE 1017
Query: 302 KDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELL 340
++ K ++L + N+++ M + + K+ K + E L
Sbjct: 1018 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL 1056
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/237 (21%), Positives = 119/237 (50%), Gaps = 13/237 (5%)
Query: 86 LQSQM-TNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEH 144
LQ Q+ L + + RLA + + E ++ ++ ++ E +G++++ ++
Sbjct: 892 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER---KKM 948
Query: 145 REKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLI 204
+++ EE L++E +R L+ +K+ A+I L+ ++ ++ D +K L+
Sbjct: 949 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD----DQNNKLSKERKLL 1004
Query: 205 QE-INDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGE 263
+E I+DL ++E + E+ + KLK+ + + S E +KE + ++ EKL K++G+
Sbjct: 1005 EERISDLTTNLAE-EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1063
Query: 264 GVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQ 320
+ ++ + + ++ E +++ K + E L AA D +I L + ++++
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKE---EELQAALARLDDEIAQKNNALKKIRELE 1117
Score = 56.2 bits (134), Expect = 1e-07
Identities = 66/304 (21%), Positives = 135/304 (44%), Gaps = 20/304 (6%)
Query: 48 ALHLVEDLRGLLEMMETD-EKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERL 106
AL + +L G + ++ D + E + L E L++ T + Q+ L
Sbjct: 1109 ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQEL 1168
Query: 107 ARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLE 166
R + ++E VL+ L ++ + +++++ ++H + V E L+Q ++ +L+
Sbjct: 1169 -RAKREQEVTVLK-KALDEETRSHEAQVQEMR---QKHAQAVEELTEQLEQFKRAKANLD 1223
Query: 167 TQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEK 226
K L E ++L +L + + + + E K + E +QE L+ K S+ + R +
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE---LQSKCSDGERARAELND 1280
Query: 227 KLKSTKDELASLKEQLEEKESEVKRLQEKL--VCKMKGEGVEIVDRDE----NFKKKLKE 280
K+ ++E+ S+ L E E + +L + + + + E++ + N KL++
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
Query: 281 KNIEVQKMKKAVESLMAANEEKDRKIEDLR-QCLNRYKKMQD----TVVLAQGKKGKDGE 335
E ++ ++ M A + +R I L Q + KK+QD L +GKK E
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 336 YEEL 339
E L
Sbjct: 1401 IENL 1404
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/255 (19%), Positives = 114/255 (44%), Gaps = 13/255 (5%)
Query: 102 YQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLS 161
++ A L+ +K++L + + L ++ G+ +++E ++ +V + +
Sbjct: 1215 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1274
Query: 162 RTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSER 221
R L + L E+ ++ L E + +D L ++ D + + E ++
Sbjct: 1275 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA---KDVASLSSQLQDTQELLQEETRQK 1331
Query: 222 LQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEK 281
L KL+ ++E SL++QL+E E E K+ E+ + + + + + ++F ++
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL 1390
Query: 282 NIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVV--------LAQGKKGKD 333
++ +K +E+L EEK + L + NR ++ D +V L + K
Sbjct: 1391 EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1450
Query: 334 GEYEELL-NSSSISS 347
++++LL +ISS
Sbjct: 1451 RKFDQLLAEEKNISS 1465
Score = 48.1 bits (113), Expect = 4e-05
Identities = 62/282 (21%), Positives = 116/282 (41%), Gaps = 46/282 (16%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEF---CLEEHREKVNATEEMLQQEL 159
Q++L K++L +S L Q+ +K++D LEE +++ E L Q+
Sbjct: 1349 QDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY 1408
Query: 160 LSRTS----LETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVS 215
+ + LE K L E+ +L + L + + E K R + L+ E ++ K +
Sbjct: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
Query: 216 EMDSERLQYEKKLKSTK--------DELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEI 267
+ + +R + E + K TK +E KE+LE +K E LV G +
Sbjct: 1469 D-ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNV 1527
Query: 268 VDRD----------ENFKKKLKEKNIEVQKMKKA---------------VESLMAANEEK 302
+ + E K +L+E E+Q + A L A +E+
Sbjct: 1528 HELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN 1587
Query: 303 DRKIEDLRQCLNRYK-----KMQDTVVLAQGKKGKDGEYEEL 339
+ K L++ L+ Y+ + + + A KK +G+ ++L
Sbjct: 1588 EEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1629
Score = 44.3 bits (103), Expect = 6e-04
Identities = 66/287 (22%), Positives = 122/287 (42%), Gaps = 28/287 (9%)
Query: 47 RALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGH-LPGNGDVYQER 105
+A L DL L E + E+ + D E L E L S ++ + L + R
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQA---DLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
Query: 106 LARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSL 165
+A+LE + E + ++D+V ++ L L R E QQ L
Sbjct: 1738 IAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKEL 1797
Query: 166 ETQ--------KLDLMAEISNLKLKLTAVEKD-RLDYEDKFRDTEGLIQEINDLRLKVSE 216
++ K + I+ L+ K+ +E+ + +K T+ L Q+ L+ + +
Sbjct: 1798 RSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQ 1857
Query: 217 MDSERL---QYEKKLKSTKDELASLKEQLEEKESEVKRL---QEKLVCKM--KGEGVEIV 268
++ ER QY+++ + + LK QLEE E E +R+ + KL ++ E E +
Sbjct: 1858 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1917
Query: 269 DRDEN-FKKKLKEKN----IEVQKM--KKAVESLMAANEEKDRKIED 308
R+ N K KL+ N + ++ ++ +E+ + EE D + D
Sbjct: 1918 GREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDAD 1964
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/222 (21%), Positives = 101/222 (45%), Gaps = 35/222 (15%)
Query: 110 ENDKESLVLQVSVLTDQVE-AQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQ 168
EN+K++ L+ ++ Q + A E+ R + EK EE L L R +L+ +
Sbjct: 1677 ENEKKAKSLEADLMQLQEDLAAAERARK-----QADLEKEELAEE-LASSLSGRNALQDE 1730
Query: 169 KLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKL 228
K L A I+ L E++ + +G ++ ++D R++ + +E+L E
Sbjct: 1731 KRRLEARIAQL--------------EEELEEEQGNMEAMSD-RVRKATQQAEQLSNELAT 1775
Query: 229 -KSTKDELASLKEQLEEKESEVK--------RLQEKLVCKMKGEGVEIVDRDENFKKKLK 279
+ST + S ++QLE + E++ ++ K + +I +E +++ +
Sbjct: 1776 ERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAR 1835
Query: 280 EKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQD 321
EK + +K+ + L +E ++ED R+ +YK+ +
Sbjct: 1836 EKQAATKSLKQKDKKL----KEILLQVEDERKMAEQYKEQAE 1873
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 68.2 bits (165), Expect = 4e-11
Identities = 76/340 (22%), Positives = 146/340 (42%), Gaps = 70/340 (20%)
Query: 51 LVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLE 110
+ + + L E +E +E + Q+ TAE ++ L+ ++ V ++ +L
Sbjct: 955 MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEIL---------VMDDQNNKLS 1005
Query: 111 NDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK- 169
+++ L ++S LT + + EK ++L +H ++ E L++E SR LE K
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1065
Query: 170 -------------LDLMAEISNLKLKLTAVEKD------RLDYE--------DKFRDTEG 202
DL A+I+ LK++L E++ RLD E K R+ EG
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1125
Query: 203 LIQEINDLRLKVSEMDSERLQYEKKLKSTKD---ELASLKEQLEE--------------K 245
I ++ + ++DSER K K +D EL +LK +LE+ +
Sbjct: 1126 HISDLQE------DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1179
Query: 246 ESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRK 305
E EV L++ L + + ++ + + + ++E ++++ K+A +L + +++
Sbjct: 1180 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Query: 306 IEDL----------RQCLNRYKKMQDTVVLAQGKKGKDGE 335
DL +Q + KK + V K DGE
Sbjct: 1240 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE 1279
Score = 56.6 bits (135), Expect = 1e-07
Identities = 57/219 (26%), Positives = 114/219 (52%), Gaps = 12/219 (5%)
Query: 126 QVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTA 185
QV Q E+++ E L++ +E+ E L+ EL + S T++ +L+ E + +L A
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQEQLQAETELYA 911
Query: 186 -VEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEE 244
E+ R+ K ++ E ++ E+ + RL+ E ++LQ E+K + ++ L+EQLEE
Sbjct: 912 EAEEMRVRLAAKKQELEEILHEM-EARLEEEEDRGQQLQAERKKMA--QQMLDLEEQLEE 968
Query: 245 KESEVKRLQEKLV---CKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEE 301
+E+ ++LQ + V K+K EI+ D+ K KE+ + +++ + L E
Sbjct: 969 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL----LEERISDLTTNLAE 1024
Query: 302 KDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELL 340
++ K ++L + N+++ M + + K+ K + E L
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL 1063
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/237 (21%), Positives = 119/237 (50%), Gaps = 13/237 (5%)
Query: 86 LQSQM-TNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEH 144
LQ Q+ L + + RLA + + E ++ ++ ++ E +G++++ ++
Sbjct: 899 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER---KKM 955
Query: 145 REKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLI 204
+++ EE L++E +R L+ +K+ A+I L+ ++ ++ D +K L+
Sbjct: 956 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD----DQNNKLSKERKLL 1011
Query: 205 QE-INDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGE 263
+E I+DL ++E + E+ + KLK+ + + S E +KE + ++ EKL K++G+
Sbjct: 1012 EERISDLTTNLAE-EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1070
Query: 264 GVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQ 320
+ ++ + + ++ E +++ K + E L AA D +I L + ++++
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKE---EELQAALARLDDEIAQKNNALKKIRELE 1124
Score = 56.2 bits (134), Expect = 1e-07
Identities = 66/304 (21%), Positives = 135/304 (44%), Gaps = 20/304 (6%)
Query: 48 ALHLVEDLRGLLEMMETD-EKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERL 106
AL + +L G + ++ D + E + L E L++ T + Q+ L
Sbjct: 1116 ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQEL 1175
Query: 107 ARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLE 166
R + ++E VL+ L ++ + +++++ ++H + V E L+Q ++ +L+
Sbjct: 1176 -RAKREQEVTVLK-KALDEETRSHEAQVQEMR---QKHAQAVEELTEQLEQFKRAKANLD 1230
Query: 167 TQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEK 226
K L E ++L +L + + + + E K + E +QE L+ K S+ + R +
Sbjct: 1231 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE---LQSKCSDGERARAELND 1287
Query: 227 KLKSTKDELASLKEQLEEKESEVKRLQEKL--VCKMKGEGVEIVDRDE----NFKKKLKE 280
K+ ++E+ S+ L E E + +L + + + + E++ + N KL++
Sbjct: 1288 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1347
Query: 281 KNIEVQKMKKAVESLMAANEEKDRKIEDLR-QCLNRYKKMQD----TVVLAQGKKGKDGE 335
E ++ ++ M A + +R I L Q + KK+QD L +GKK E
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 336 YEEL 339
E L
Sbjct: 1408 IENL 1411
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/255 (19%), Positives = 114/255 (44%), Gaps = 13/255 (5%)
Query: 102 YQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLS 161
++ A L+ +K++L + + L ++ G+ +++E ++ +V + +
Sbjct: 1222 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1281
Query: 162 RTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSER 221
R L + L E+ ++ L E + +D L ++ D + + E ++
Sbjct: 1282 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA---KDVASLSSQLQDTQELLQEETRQK 1338
Query: 222 LQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEK 281
L KL+ ++E SL++QL+E E E K+ E+ + + + + + ++F ++
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL 1397
Query: 282 NIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVV--------LAQGKKGKD 333
++ +K +E+L EEK + L + NR ++ D +V L + K
Sbjct: 1398 EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1457
Query: 334 GEYEELL-NSSSISS 347
++++LL +ISS
Sbjct: 1458 RKFDQLLAEEKNISS 1472
Score = 48.1 bits (113), Expect = 4e-05
Identities = 62/282 (21%), Positives = 116/282 (41%), Gaps = 46/282 (16%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEF---CLEEHREKVNATEEMLQQEL 159
Q++L K++L +S L Q+ +K++D LEE +++ E L Q+
Sbjct: 1356 QDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY 1415
Query: 160 LSRTS----LETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVS 215
+ + LE K L E+ +L + L + + E K R + L+ E ++ K +
Sbjct: 1416 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1475
Query: 216 EMDSERLQYEKKLKSTK--------DELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEI 267
+ + +R + E + K TK +E KE+LE +K E LV G +
Sbjct: 1476 D-ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNV 1534
Query: 268 VDRD----------ENFKKKLKEKNIEVQKMKKA---------------VESLMAANEEK 302
+ + E K +L+E E+Q + A L A +E+
Sbjct: 1535 HELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN 1594
Query: 303 DRKIEDLRQCLNRYK-----KMQDTVVLAQGKKGKDGEYEEL 339
+ K L++ L+ Y+ + + + A KK +G+ ++L
Sbjct: 1595 EEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1636
Score = 44.3 bits (103), Expect = 6e-04
Identities = 66/287 (22%), Positives = 122/287 (42%), Gaps = 28/287 (9%)
Query: 47 RALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGH-LPGNGDVYQER 105
+A L DL L E + E+ + D E L E L S ++ + L + R
Sbjct: 1688 KAKSLEADLMQLQEDLAAAERARKQA---DLEKEELAEELASSLSGRNALQDEKRRLEAR 1744
Query: 106 LARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSL 165
+A+LE + E + ++D+V ++ L L R E QQ L
Sbjct: 1745 IAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKEL 1804
Query: 166 ETQ--------KLDLMAEISNLKLKLTAVEKD-RLDYEDKFRDTEGLIQEINDLRLKVSE 216
++ K + I+ L+ K+ +E+ + +K T+ L Q+ L+ + +
Sbjct: 1805 RSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQ 1864
Query: 217 MDSERL---QYEKKLKSTKDELASLKEQLEEKESEVKRL---QEKLVCKM--KGEGVEIV 268
++ ER QY+++ + + LK QLEE E E +R+ + KL ++ E E +
Sbjct: 1865 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1924
Query: 269 DRDEN-FKKKLKEKN----IEVQKM--KKAVESLMAANEEKDRKIED 308
R+ N K KL+ N + ++ ++ +E+ + EE D + D
Sbjct: 1925 GREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDAD 1971
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/222 (21%), Positives = 101/222 (45%), Gaps = 35/222 (15%)
Query: 110 ENDKESLVLQVSVLTDQVE-AQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQ 168
EN+K++ L+ ++ Q + A E+ R + EK EE L L R +L+ +
Sbjct: 1684 ENEKKAKSLEADLMQLQEDLAAAERARK-----QADLEKEELAEE-LASSLSGRNALQDE 1737
Query: 169 KLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKL 228
K L A I+ L E++ + +G ++ ++D R++ + +E+L E
Sbjct: 1738 KRRLEARIAQL--------------EEELEEEQGNMEAMSD-RVRKATQQAEQLSNELAT 1782
Query: 229 -KSTKDELASLKEQLEEKESEVK--------RLQEKLVCKMKGEGVEIVDRDENFKKKLK 279
+ST + S ++QLE + E++ ++ K + +I +E +++ +
Sbjct: 1783 ERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAR 1842
Query: 280 EKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQD 321
EK + +K+ + L +E ++ED R+ +YK+ +
Sbjct: 1843 EKQAATKSLKQKDKKL----KEILLQVEDERKMAEQYKEQAE 1880
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 68.2 bits (165), Expect = 4e-11
Identities = 76/340 (22%), Positives = 146/340 (42%), Gaps = 70/340 (20%)
Query: 51 LVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLE 110
+ + + L E +E +E + Q+ TAE ++ L+ ++ V ++ +L
Sbjct: 955 MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEIL---------VMDDQNNKLS 1005
Query: 111 NDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK- 169
+++ L ++S LT + + EK ++L +H ++ E L++E SR LE K
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1065
Query: 170 -------------LDLMAEISNLKLKLTAVEKD------RLDYE--------DKFRDTEG 202
DL A+I+ LK++L E++ RLD E K R+ EG
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1125
Query: 203 LIQEINDLRLKVSEMDSERLQYEKKLKSTKD---ELASLKEQLEE--------------K 245
I ++ + ++DSER K K +D EL +LK +LE+ +
Sbjct: 1126 HISDLQE------DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1179
Query: 246 ESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRK 305
E EV L++ L + + ++ + + + ++E ++++ K+A +L + +++
Sbjct: 1180 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Query: 306 IEDL----------RQCLNRYKKMQDTVVLAQGKKGKDGE 335
DL +Q + KK + V K DGE
Sbjct: 1240 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE 1279
Score = 56.6 bits (135), Expect = 1e-07
Identities = 57/219 (26%), Positives = 114/219 (52%), Gaps = 12/219 (5%)
Query: 126 QVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTA 185
QV Q E+++ E L++ +E+ E L+ EL + S T++ +L+ E + +L A
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQEQLQAETELYA 911
Query: 186 -VEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEE 244
E+ R+ K ++ E ++ E+ + RL+ E ++LQ E+K + ++ L+EQLEE
Sbjct: 912 EAEEMRVRLAAKKQELEEILHEM-EARLEEEEDRGQQLQAERKKMA--QQMLDLEEQLEE 968
Query: 245 KESEVKRLQEKLV---CKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEE 301
+E+ ++LQ + V K+K EI+ D+ K KE+ + +++ + L E
Sbjct: 969 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL----LEERISDLTTNLAE 1024
Query: 302 KDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELL 340
++ K ++L + N+++ M + + K+ K + E L
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL 1063
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/237 (21%), Positives = 119/237 (50%), Gaps = 13/237 (5%)
Query: 86 LQSQM-TNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEH 144
LQ Q+ L + + RLA + + E ++ ++ ++ E +G++++ ++
Sbjct: 899 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER---KKM 955
Query: 145 REKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLI 204
+++ EE L++E +R L+ +K+ A+I L+ ++ ++ D +K L+
Sbjct: 956 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD----DQNNKLSKERKLL 1011
Query: 205 QE-INDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGE 263
+E I+DL ++E + E+ + KLK+ + + S E +KE + ++ EKL K++G+
Sbjct: 1012 EERISDLTTNLAE-EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1070
Query: 264 GVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQ 320
+ ++ + + ++ E +++ K + E L AA D +I L + ++++
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKE---EELQAALARLDDEIAQKNNALKKIRELE 1124
Score = 56.2 bits (134), Expect = 1e-07
Identities = 66/304 (21%), Positives = 135/304 (44%), Gaps = 20/304 (6%)
Query: 48 ALHLVEDLRGLLEMMETD-EKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERL 106
AL + +L G + ++ D + E + L E L++ T + Q+ L
Sbjct: 1116 ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQEL 1175
Query: 107 ARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLE 166
R + ++E VL+ L ++ + +++++ ++H + V E L+Q ++ +L+
Sbjct: 1176 -RAKREQEVTVLK-KALDEETRSHEAQVQEMR---QKHAQAVEELTEQLEQFKRAKANLD 1230
Query: 167 TQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEK 226
K L E ++L +L + + + + E K + E +QE L+ K S+ + R +
Sbjct: 1231 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE---LQSKCSDGERARAELND 1287
Query: 227 KLKSTKDELASLKEQLEEKESEVKRLQEKL--VCKMKGEGVEIVDRDE----NFKKKLKE 280
K+ ++E+ S+ L E E + +L + + + + E++ + N KL++
Sbjct: 1288 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1347
Query: 281 KNIEVQKMKKAVESLMAANEEKDRKIEDLR-QCLNRYKKMQD----TVVLAQGKKGKDGE 335
E ++ ++ M A + +R I L Q + KK+QD L +GKK E
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 336 YEEL 339
E L
Sbjct: 1408 IENL 1411
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/255 (19%), Positives = 114/255 (44%), Gaps = 13/255 (5%)
Query: 102 YQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLS 161
++ A L+ +K++L + + L ++ G+ +++E ++ +V + +
Sbjct: 1222 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1281
Query: 162 RTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSER 221
R L + L E+ ++ L E + +D L ++ D + + E ++
Sbjct: 1282 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA---KDVASLSSQLQDTQELLQEETRQK 1338
Query: 222 LQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEK 281
L KL+ ++E SL++QL+E E E K+ E+ + + + + + ++F ++
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL 1397
Query: 282 NIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVV--------LAQGKKGKD 333
++ +K +E+L EEK + L + NR ++ D +V L + K
Sbjct: 1398 EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1457
Query: 334 GEYEELL-NSSSISS 347
++++LL +ISS
Sbjct: 1458 RKFDQLLAEEKNISS 1472
Score = 48.1 bits (113), Expect = 4e-05
Identities = 62/282 (21%), Positives = 116/282 (41%), Gaps = 46/282 (16%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEF---CLEEHREKVNATEEMLQQEL 159
Q++L K++L +S L Q+ +K++D LEE +++ E L Q+
Sbjct: 1356 QDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY 1415
Query: 160 LSRTS----LETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVS 215
+ + LE K L E+ +L + L + + E K R + L+ E ++ K +
Sbjct: 1416 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1475
Query: 216 EMDSERLQYEKKLKSTK--------DELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEI 267
+ + +R + E + K TK +E KE+LE +K E LV G +
Sbjct: 1476 D-ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNV 1534
Query: 268 VDRD----------ENFKKKLKEKNIEVQKMKKA---------------VESLMAANEEK 302
+ + E K +L+E E+Q + A L A +E+
Sbjct: 1535 HELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN 1594
Query: 303 DRKIEDLRQCLNRYK-----KMQDTVVLAQGKKGKDGEYEEL 339
+ K L++ L+ Y+ + + + A KK +G+ ++L
Sbjct: 1595 EEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1636
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/219 (23%), Positives = 92/219 (42%), Gaps = 16/219 (7%)
Query: 47 RALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGH-LPGNGDVYQER 105
+A L DL L E + E+ + D E L E L S ++ + L + R
Sbjct: 1688 KAKSLEADLMQLQEDLAAAERARKQA---DLEKEELAEELASSLSGRNALQDEKRRLEAR 1744
Query: 106 LARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSL 165
+A+LE + E + ++D+V ++ L L R E QQ L
Sbjct: 1745 IAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKEL 1804
Query: 166 ETQ--------KLDLMAEISNLKLKLTAVEKD-RLDYEDKFRDTEGLIQEINDLRLKVSE 216
++ K + I+ L+ K+ +E+ + +K T+ L Q+ L+ + +
Sbjct: 1805 RSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQ 1864
Query: 217 MDSERL---QYEKKLKSTKDELASLKEQLEEKESEVKRL 252
++ ER QY+++ + + LK QLEE E E +R+
Sbjct: 1865 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1903
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/222 (21%), Positives = 101/222 (45%), Gaps = 35/222 (15%)
Query: 110 ENDKESLVLQVSVLTDQVE-AQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQ 168
EN+K++ L+ ++ Q + A E+ R + EK EE L L R +L+ +
Sbjct: 1684 ENEKKAKSLEADLMQLQEDLAAAERARK-----QADLEKEELAEE-LASSLSGRNALQDE 1737
Query: 169 KLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKL 228
K L A I+ L E++ + +G ++ ++D R++ + +E+L E
Sbjct: 1738 KRRLEARIAQL--------------EEELEEEQGNMEAMSD-RVRKATQQAEQLSNELAT 1782
Query: 229 -KSTKDELASLKEQLEEKESEVK--------RLQEKLVCKMKGEGVEIVDRDENFKKKLK 279
+ST + S ++QLE + E++ ++ K + +I +E +++ +
Sbjct: 1783 ERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAR 1842
Query: 280 EKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQD 321
EK + +K+ + L +E ++ED R+ +YK+ +
Sbjct: 1843 EKQAATKSLKQKDKKL----KEILLQVEDERKMAEQYKEQAE 1880
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 68.2 bits (165), Expect = 4e-11
Identities = 76/340 (22%), Positives = 146/340 (42%), Gaps = 70/340 (20%)
Query: 51 LVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLE 110
+ + + L E +E +E + Q+ TAE ++ L+ ++ V ++ +L
Sbjct: 948 MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEIL---------VMDDQNNKLS 998
Query: 111 NDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK- 169
+++ L ++S LT + + EK ++L +H ++ E L++E SR LE K
Sbjct: 999 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 1058
Query: 170 -------------LDLMAEISNLKLKLTAVEKD------RLDYE--------DKFRDTEG 202
DL A+I+ LK++L E++ RLD E K R+ EG
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
Query: 203 LIQEINDLRLKVSEMDSERLQYEKKLKSTKD---ELASLKEQLEE--------------K 245
I ++ + ++DSER K K +D EL +LK +LE+ +
Sbjct: 1119 HISDLQE------DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR 1172
Query: 246 ESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRK 305
E EV L++ L + + ++ + + + ++E ++++ K+A +L + +++
Sbjct: 1173 EQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Query: 306 IEDL----------RQCLNRYKKMQDTVVLAQGKKGKDGE 335
DL +Q + KK + V K DGE
Sbjct: 1233 NADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE 1272
Score = 56.6 bits (135), Expect = 1e-07
Identities = 57/219 (26%), Positives = 114/219 (52%), Gaps = 12/219 (5%)
Query: 126 QVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTA 185
QV Q E+++ E L++ +E+ E L+ EL + S T++ +L+ E + +L A
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELK-ELEQKHSQLTEEKNLLQEQLQAETELYA 904
Query: 186 -VEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEE 244
E+ R+ K ++ E ++ E+ + RL+ E ++LQ E+K + ++ L+EQLEE
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEM-EARLEEEEDRGQQLQAERKKMA--QQMLDLEEQLEE 961
Query: 245 KESEVKRLQEKLV---CKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEE 301
+E+ ++LQ + V K+K EI+ D+ K KE+ + +++ + L E
Sbjct: 962 EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL----LEERISDLTTNLAE 1017
Query: 302 KDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELL 340
++ K ++L + N+++ M + + K+ K + E L
Sbjct: 1018 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL 1056
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/237 (21%), Positives = 119/237 (50%), Gaps = 13/237 (5%)
Query: 86 LQSQM-TNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEH 144
LQ Q+ L + + RLA + + E ++ ++ ++ E +G++++ ++
Sbjct: 892 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER---KKM 948
Query: 145 REKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLI 204
+++ EE L++E +R L+ +K+ A+I L+ ++ ++ D +K L+
Sbjct: 949 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD----DQNNKLSKERKLL 1004
Query: 205 QE-INDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGE 263
+E I+DL ++E + E+ + KLK+ + + S E +KE + ++ EKL K++G+
Sbjct: 1005 EERISDLTTNLAE-EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1063
Query: 264 GVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQ 320
+ ++ + + ++ E +++ K + E L AA D +I L + ++++
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKE---EELQAALARLDDEIAQKNNALKKIRELE 1117
Score = 56.2 bits (134), Expect = 1e-07
Identities = 66/304 (21%), Positives = 135/304 (44%), Gaps = 20/304 (6%)
Query: 48 ALHLVEDLRGLLEMMETD-EKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERL 106
AL + +L G + ++ D + E + L E L++ T + Q+ L
Sbjct: 1109 ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQEL 1168
Query: 107 ARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLE 166
R + ++E VL+ L ++ + +++++ ++H + V E L+Q ++ +L+
Sbjct: 1169 -RAKREQEVTVLK-KALDEETRSHEAQVQEMR---QKHAQAVEELTEQLEQFKRAKANLD 1223
Query: 167 TQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEK 226
K L E ++L +L + + + + E K + E +QE L+ K S+ + R +
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE---LQSKCSDGERARAELND 1280
Query: 227 KLKSTKDELASLKEQLEEKESEVKRLQEKL--VCKMKGEGVEIVDRDE----NFKKKLKE 280
K+ ++E+ S+ L E E + +L + + + + E++ + N KL++
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
Query: 281 KNIEVQKMKKAVESLMAANEEKDRKIEDLR-QCLNRYKKMQD----TVVLAQGKKGKDGE 335
E ++ ++ M A + +R I L Q + KK+QD L +GKK E
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 336 YEEL 339
E L
Sbjct: 1401 IENL 1404
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/255 (19%), Positives = 114/255 (44%), Gaps = 13/255 (5%)
Query: 102 YQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLS 161
++ A L+ +K++L + + L ++ G+ +++E ++ +V + +
Sbjct: 1215 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1274
Query: 162 RTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSER 221
R L + L E+ ++ L E + +D L ++ D + + E ++
Sbjct: 1275 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA---KDVASLSSQLQDTQELLQEETRQK 1331
Query: 222 LQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEK 281
L KL+ ++E SL++QL+E E E K+ E+ + + + + + ++F ++
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL 1390
Query: 282 NIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVV--------LAQGKKGKD 333
++ +K +E+L EEK + L + NR ++ D +V L + K
Sbjct: 1391 EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1450
Query: 334 GEYEELL-NSSSISS 347
++++LL +ISS
Sbjct: 1451 RKFDQLLAEEKNISS 1465
Score = 48.1 bits (113), Expect = 4e-05
Identities = 62/282 (21%), Positives = 116/282 (41%), Gaps = 46/282 (16%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEF---CLEEHREKVNATEEMLQQEL 159
Q++L K++L +S L Q+ +K++D LEE +++ E L Q+
Sbjct: 1349 QDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY 1408
Query: 160 LSRTS----LETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVS 215
+ + LE K L E+ +L + L + + E K R + L+ E ++ K +
Sbjct: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
Query: 216 EMDSERLQYEKKLKSTK--------DELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEI 267
+ + +R + E + K TK +E KE+LE +K E LV G +
Sbjct: 1469 D-ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNV 1527
Query: 268 VDRD----------ENFKKKLKEKNIEVQKMKKA---------------VESLMAANEEK 302
+ + E K +L+E E+Q + A L A +E+
Sbjct: 1528 HELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN 1587
Query: 303 DRKIEDLRQCLNRYK-----KMQDTVVLAQGKKGKDGEYEEL 339
+ K L++ L+ Y+ + + + A KK +G+ ++L
Sbjct: 1588 EEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1629
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/219 (23%), Positives = 92/219 (42%), Gaps = 16/219 (7%)
Query: 47 RALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGH-LPGNGDVYQER 105
+A L DL L E + E+ + D E L E L S ++ + L + R
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQA---DLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
Query: 106 LARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSL 165
+A+LE + E + ++D+V ++ L L R E QQ L
Sbjct: 1738 IAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKEL 1797
Query: 166 ETQ--------KLDLMAEISNLKLKLTAVEKD-RLDYEDKFRDTEGLIQEINDLRLKVSE 216
++ K + I+ L+ K+ +E+ + +K T+ L Q+ L+ + +
Sbjct: 1798 RSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQ 1857
Query: 217 MDSERL---QYEKKLKSTKDELASLKEQLEEKESEVKRL 252
++ ER QY+++ + + LK QLEE E E +R+
Sbjct: 1858 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1896
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/222 (21%), Positives = 101/222 (45%), Gaps = 35/222 (15%)
Query: 110 ENDKESLVLQVSVLTDQVE-AQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQ 168
EN+K++ L+ ++ Q + A E+ R + EK EE L L R +L+ +
Sbjct: 1677 ENEKKAKSLEADLMQLQEDLAAAERARK-----QADLEKEELAEE-LASSLSGRNALQDE 1730
Query: 169 KLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKL 228
K L A I+ L E++ + +G ++ ++D R++ + +E+L E
Sbjct: 1731 KRRLEARIAQL--------------EEELEEEQGNMEAMSD-RVRKATQQAEQLSNELAT 1775
Query: 229 -KSTKDELASLKEQLEEKESEVK--------RLQEKLVCKMKGEGVEIVDRDENFKKKLK 279
+ST + S ++QLE + E++ ++ K + +I +E +++ +
Sbjct: 1776 ERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAR 1835
Query: 280 EKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQD 321
EK + +K+ + L +E ++ED R+ +YK+ +
Sbjct: 1836 EKQAATKSLKQKDKKL----KEILLQVEDERKMAEQYKEQAE 1873
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 67.4 bits (163), Expect = 6e-11
Identities = 78/314 (24%), Positives = 149/314 (47%), Gaps = 32/314 (10%)
Query: 54 DLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDK 113
DL +E M T +E LR Q +S E + + HL ++ + NDK
Sbjct: 213 DLNNNIEKMITAFEE-LRVQAENSRLEMHFKLKEDYEKIQHL-------EQEYKKEINDK 264
Query: 114 ESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEE--MLQQELLSRTSLETQKLD 171
E QVS+L Q+ + K++DL F LEE R+KVN EE LQ E L + S+E Q
Sbjct: 265 EK---QVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENL-KQSIEKQH-H 319
Query: 172 LMAEISNLKLKL-TAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKS 230
L E+ ++K+ L +V + ED T+ + Q + ++ E + R + +
Sbjct: 320 LTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTE 379
Query: 231 TKDELASLKEQLEEKESEVKRLQEK---LVCKMKGEGVEIVDRDENFKKKLKEKNIEVQK 287
+ + SL+E L ++ +++ +++ L +++ + E+ E K K +E+++
Sbjct: 380 FETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSEL----EEMTKLTNNKEVELEE 435
Query: 288 MKKAV---ESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNSSS 344
+KK + E+L+ N++ ++ E+L+ Q+ + L Q ++ + + E L + +
Sbjct: 436 LKKVLGEKETLLYENKQFEKIAEELK------GTEQELIGLLQAREKEVHDLEIQLTAIT 489
Query: 345 ISSLLDAQGFSDLE 358
S ++ DL+
Sbjct: 490 TSEQYYSKEVKDLK 503
Score = 50.4 bits (119), Expect = 8e-06
Identities = 60/249 (24%), Positives = 112/249 (44%), Gaps = 46/249 (18%)
Query: 109 LENDKESLVLQVSVLTDQVEAQGEKIRDLE----FCLEEHREKVNATEEMLQQEL----- 159
LE D + + LT++ E Q E+ F + E V + EE+L+ E
Sbjct: 341 LEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEK 400
Query: 160 ----LSRTSLETQK----LDLMAEISNLK------LKLTAVEKDRLDYEDK--------F 197
L ++E QK L+ M +++N K LK EK+ L YE+K
Sbjct: 401 NEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEEL 460
Query: 198 RDTE----GLIQ----EINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEV 249
+ TE GL+Q E++DL ++++ + + Y K++K K EL + K + E S
Sbjct: 461 KGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHC 520
Query: 250 KRL---QEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKI 306
+L ++L + +E+ ++ E+ K++ ++M K +E+L + ++
Sbjct: 521 NKLSLENKELTQETSDMTLELKNQQEDINNNKKQE----ERMLKQIENLQETETQLRNEL 576
Query: 307 EDLRQCLNR 315
E +R+ L +
Sbjct: 577 EYVREELKQ 585
Score = 49.7 bits (117), Expect = 1e-05
Identities = 50/227 (22%), Positives = 101/227 (44%), Gaps = 19/227 (8%)
Query: 110 ENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK 169
E + L +Q++ +T + ++++DL+ LE + K + L L +
Sbjct: 475 EKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQET 534
Query: 170 LDLMAEISNLKLKLTAVEKDR---LDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEK 226
D+ E+ N + + +K L + ++TE ++ N+L E+ +R + +
Sbjct: 535 SDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLR--NELEYVREELKQKRDEVKC 592
Query: 227 KLKSTKDELASLKEQLEEKESEVKRL-QEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEV 285
KL +++ +L++Q+E K ++ L QE K KG K+L I+V
Sbjct: 593 KLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAE---------SKQLNVYEIKV 643
Query: 286 QKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGK 332
K++ +ES ++K +I D Q KK+ + +L + +K K
Sbjct: 644 NKLELELESA----KQKFGEITDTYQKEIEDKKISEENLLEEVEKAK 686
Score = 47.4 bits (111), Expect = 7e-05
Identities = 57/253 (22%), Positives = 121/253 (47%), Gaps = 28/253 (11%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQE---L 159
QE +L N+ E + ++ D+V+ + +K + L + E N E LQQE L
Sbjct: 566 QETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKAL 625
Query: 160 LSRTSLETQKLDLM-AEISNLKLKLTAVEKD--------RLDYEDKFRDTEGLIQEINDL 210
+ + E+++L++ +++ L+L+L + ++ + + EDK E L++E+
Sbjct: 626 KKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKA 685
Query: 211 RLKVSEMDSERLQYEKKLKSTKDELASLKEQ--------LEEKESEV------KRLQEKL 256
++ E + + +K+ + E+ +L E+ +EE++SE+ ++ Q L
Sbjct: 686 KVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSL 745
Query: 257 VCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKK-AVESLMAANEEKDRKIED-LRQCLN 314
++ E + + KK+L+ + E +K+K+ A E+ E+KD+K + L +
Sbjct: 746 RASLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPE 805
Query: 315 RYKKMQDTVVLAQ 327
Y K+ V +Q
Sbjct: 806 IYWKLDSKAVPSQ 818
Score = 38.1 bits (87), Expect = 0.042
Identities = 93/441 (21%), Positives = 168/441 (38%), Gaps = 98/441 (22%)
Query: 97 GNGDV-YQERL--ARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLE-EHREKVNATE 152
GN D YQE L + LEN + +S + ++ + EKI+ + E E R+K + +
Sbjct: 81 GNSDCHYQEGLKDSDLENSEG-----LSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQ 135
Query: 153 EMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVE-KDRLDYEDKFRDTEGLIQEINDLR 211
E ++++ Q+L E +LKL+ E KD + + R L++E
Sbjct: 136 E--NRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARS 193
Query: 212 L-KVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDR 270
K + + ER + + + + + EE + + + ++ K+K + +I
Sbjct: 194 AEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHL 253
Query: 271 DENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKK 330
++ +KK++ +K +K V L+ EK+ K++DL L + +
Sbjct: 254 EQEYKKEINDK-------EKQVSLLLIQITEKENKMKDL-------------TFLLEESR 293
Query: 331 GKDGEYEE--LLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTIL 388
K + EE L S ++ ++ Q E + S
Sbjct: 294 DKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRS------------------- 334
Query: 389 QVSIPSLLPATVSMETSEKSKLTPKPETSFEEND----GNIILGATVDTQLCD------- 437
VS L + + T +LT + ET EE++ + + +T +C
Sbjct: 335 -VSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRT 393
Query: 438 ------------KLLTSSLQ-KSSSLGNLKKETSD------------GEKETI------- 465
K+LT LQ KSS L + K T++ GEKET+
Sbjct: 394 EQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQF 453
Query: 466 QKTSEDRAPAESRPFGTLPPR 486
+K +E+ E G L R
Sbjct: 454 EKIAEELKGTEQELIGLLQAR 474
Score = 38.1 bits (87), Expect = 0.042
Identities = 44/190 (23%), Positives = 81/190 (42%), Gaps = 42/190 (22%)
Query: 100 DVYQERLARLENDKESLVLQVS---VLTDQ-VEAQGE-------KIRDLEFCLEEHREKV 148
D YQ+ + + +E+L+ +V V+ D+ V+ Q E KI ++ +E+H+ +
Sbjct: 662 DTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQY 721
Query: 149 NATEEMLQQELLSRTSLETQKLDLMA----EISNLKLKLTAVEKDRLDYEDKFRDTEGLI 204
+ E EL S E ++ L A E+SNLK +L +V+K
Sbjct: 722 DKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKAELLSVKK---------------- 765
Query: 205 QEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEG 264
+++ ER + EK + K+ A+LKE+ ++K ++ K+ +
Sbjct: 766 -----------QLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPEIYWKLDSKA 814
Query: 265 VEIVDRDENF 274
V NF
Sbjct: 815 VPSQTVSRNF 824
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 67.0 bits (162), Expect = 8e-11
Identities = 57/217 (26%), Positives = 102/217 (47%), Gaps = 11/217 (5%)
Query: 109 LENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQ 168
LEN++ L +V VL K + +E L+E + K N E + + T L+ +
Sbjct: 1222 LENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVE 1281
Query: 169 KLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKL 228
++ +S K + + KD E + +DT+ L+QE N +L +S KL
Sbjct: 1282 LDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLS----------TKL 1331
Query: 229 KSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKM 288
K +DE S +EQLEE+E E K EK + + + ++ + E+ L+ +K+
Sbjct: 1332 KQVEDEKNSFREQLEEEE-EAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL 1390
Query: 289 KKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVL 325
+K +E L +EEK + L + R ++ D +++
Sbjct: 1391 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLV 1427
Score = 65.9 bits (159), Expect = 2e-10
Identities = 99/475 (20%), Positives = 200/475 (42%), Gaps = 71/475 (14%)
Query: 53 EDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLEND 112
++++ L E +E +E + Q+ T E ++ L+ + + +++ +L +
Sbjct: 943 QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQI---------ILEDQNCKLAKE 993
Query: 113 KESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR---------- 162
K+ L +++ T + + EK + L +H + EE L++E R
Sbjct: 994 KKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 163 ----TSLETQKLDLMAEISNLKLKLTAVEKDR----LDYEDKFRDTEGLIQEINDLRLKV 214
T L Q +L A+I+ LK++L E++ E++ +++I +L ++
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 215 SEM----DSERLQYEKKLKSTKD---ELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEI 267
SE+ +SER K K +D EL +LK +LE+ QE + + + V I
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQE--LRSKREQEVNI 1171
Query: 268 VDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQ 327
+ + +++ K ++Q+M+ ++ + +E+L + L + K+++ L +
Sbjct: 1172 LKK--TLEEEAKTHEAQIQEMR----------QKHSQAVEELAEQLEQTKRVKAN--LEK 1217
Query: 328 GKKGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEF--HT 385
K+ + E EL N + LL +G S+ ++ + V E
Sbjct: 1218 AKQTLENERGELAN--EVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKV 1275
Query: 386 TILQVSIPSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQ 445
T LQV + + + +S S+ SKLT D + + DTQ +LL +
Sbjct: 1276 TKLQVELDN-VTGLLSQSDSKSSKLT---------KDFSALESQLQDTQ---ELLQEENR 1322
Query: 446 KSSSLGNLKKETSDGEKETIQKTSEDRAPAE---SRPFGTLPPRPPGQDTSMDDN 497
+ SL K+ D EK + ++ E+ A+ + TL + M+D+
Sbjct: 1323 QKLSLSTKLKQVED-EKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDS 1376
Score = 58.9 bits (141), Expect = 2e-08
Identities = 59/228 (25%), Positives = 105/228 (46%), Gaps = 39/228 (17%)
Query: 117 VLQVSVLTDQVEAQGE---KIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLM 173
+LQVS +++ A+ E K+R+ + E ++ + L E L + +L
Sbjct: 837 LLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELC 896
Query: 174 AEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKD 233
AE L+ +LTA +++ E+ D E ++E E + LQ EKK +
Sbjct: 897 AEAEELRARLTAKKQE---LEEICHDLEARVEE--------EEERCQHLQAEKK--KMQQ 943
Query: 234 ELASLKEQLEEKES--------------EVKRLQEKLV------CKMKGEGVEIVDRDEN 273
+ L+EQLEE+ES ++K+L+E+ + CK+ E + DR
Sbjct: 944 NIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAE 1003
Query: 274 FKKKL---KEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKK 318
F L +EK+ + K+K E+++ EE+ R+ E RQ L + ++
Sbjct: 1004 FTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRR 1051
Score = 52.8 bits (125), Expect = 2e-06
Identities = 68/298 (22%), Positives = 122/298 (40%), Gaps = 76/298 (25%)
Query: 102 YQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLE------------------E 143
++E+L E K +L Q++ L QV +K+ D CLE
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 144 HREKVNA------TEEMLQQEL-----------LSRTSLETQ--KLD-LMAEISNLKLKL 183
H EKV A T+ LQQEL S +LE + K D L+AE + K
Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKY 1460
Query: 184 TAVEKDRLDYEDKFRDT------------------------------EGLIQEINDLRLK 213
A E+DR + E + ++T E L+ +D+
Sbjct: 1461 -AEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519
Query: 214 VSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDEN 273
V E++ + E++++ K +L L+++L+ E RL+ L ++ RDE
Sbjct: 1520 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ 1579
Query: 274 FKKKLKEKNIEVQKMKKAVES-------LMAANEEKDRKIEDLRQCLNRYKKMQDTVV 324
++K K+ +V++M+ +E +AA ++ + ++DL ++ K +D +
Sbjct: 1580 SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAI 1637
Score = 47.8 bits (112), Expect = 5e-05
Identities = 48/230 (20%), Positives = 105/230 (45%), Gaps = 22/230 (9%)
Query: 105 RLARLEND---KESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREK-------VNATEEM 154
+L LE++ E L++ V ++AQ E RDL+ E+ EK V E
Sbjct: 1540 QLEELEDELQATEDAKLRLEVNLQAMKAQFE--RDLQGRDEQSEEKKKQLVRQVREMEAE 1597
Query: 155 LQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEG----LIQEINDL 210
L+ E R+ + L ++ +L+ + + K+R + + R + ++E++D
Sbjct: 1598 LEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT 1657
Query: 211 RLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKL------VCKMKGEG 264
R E+ ++ + EKKLKS + E+ L+E+L E ++ Q++ + G+G
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKG 1717
Query: 265 VEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLN 314
++ + ++ + E+++ + E + ++ + +I+ + LN
Sbjct: 1718 ALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN 1767
Score = 43.5 bits (101), Expect = 0.001
Identities = 38/161 (23%), Positives = 68/161 (42%), Gaps = 12/161 (7%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR 162
+ R+A+LE + E ++ D+++ +I + L R E QQ
Sbjct: 1728 EARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQN 1787
Query: 163 TSLETQKLDLMAEI-SNLKLKLTAVE------KDRLDYEDKFRDT-----EGLIQEINDL 210
L+ + ++ + S K +TA+E +++LD E K R +++ D+
Sbjct: 1788 KELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV 1847
Query: 211 RLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKR 251
L+V + QY+ + L LK QLEE E E +R
Sbjct: 1848 LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQR 1888
Score = 41.2 bits (95), Expect = 0.005
Identities = 63/331 (19%), Positives = 137/331 (41%), Gaps = 56/331 (16%)
Query: 51 LVEDLRGLLEMMET-----DEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQER 105
L +DL GL + E D+ E + ++ + LV+ + + +L + Q++
Sbjct: 1390 LQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL----EKKQKK 1445
Query: 106 LARLENDKESLVLQVSVLTDQVEAQGE----KIRDLEFCLEEHREKVNATEEMLQQELLS 161
+L +++++ + + D+ EA+ K L LEE E+ E + +Q
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTE 1505
Query: 162 RTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVS-EMDSE 220
L + K D+ + L+ A+E+ + + + + E +Q D +L++ + +
Sbjct: 1506 MEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAM 1565
Query: 221 RLQYEKKLKSTKDELASLKEQLE------EKESEVKRLQEKL-VCKMKGEGVEIVD---- 269
+ Q+E+ L+ ++ K+QL E E E +R Q + V K +++ D
Sbjct: 1566 KAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAH 1625
Query: 270 -------RDENFKK------KLKEKNIEVQKMKKAVESLMAANEEKDRKIEDL------- 309
RDE K+ ++K+ E+ + + E ++A +E ++K++ +
Sbjct: 1626 IDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQL 1685
Query: 310 -----------RQCLNRYKKMQDTVVLAQGK 329
RQ ++ D + + GK
Sbjct: 1686 QEELAAAERAKRQAQQERDELADEIANSSGK 1716
Score = 40.8 bits (94), Expect = 0.006
Identities = 67/305 (21%), Positives = 132/305 (43%), Gaps = 47/305 (15%)
Query: 54 DLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMT--------------NGHLPG-- 97
DL+G E E +K+ +R Q+ + AE E Q M H+
Sbjct: 1572 DLQGRDEQSEEKKKQLVR-QVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630
Query: 98 -NGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQ 156
N D ++L +L+ + + ++ D A E+I E+ + + A LQ
Sbjct: 1631 KNRDEAIKQLRKLQAQMKDCMREL----DDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 157 QELLS----RTSLETQKLDLMAEISNLKLK--LTAVEKDRLD-----YEDKFRDTEGLIQ 205
+EL + + + ++ +L EI+N K L EK RL+ E++ + +G +
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 206 EINDLRLKVSEMDSERLQYEKKL-KSTKDELASLKEQLEEKESEVK-RLQE-------KL 256
IND RLK + + +++ + L +S + + ++QLE + E+K +LQE K
Sbjct: 1747 LIND-RLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKY 1805
Query: 257 VCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRY 316
+ +I +E + KE+ +++++ + L ++ +++D R+ +Y
Sbjct: 1806 KASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKL----KDVLLQVDDERRNAEQY 1861
Query: 317 KKMQD 321
K D
Sbjct: 1862 KDQAD 1866
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 64.3 bits (155), Expect = 5e-10
Identities = 49/198 (24%), Positives = 101/198 (51%), Gaps = 19/198 (9%)
Query: 125 DQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLT 184
+++ Q EKIR+ E ++E EK+ EE + ++ E + + ++ + K+
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQ-------EEEMQEQEEKMRRQEEKIR 442
Query: 185 AVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEE 244
EK + E+K R+ E ++QE + K+ E + + + E K++ ++++ +E++ E
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEE---KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIRE 499
Query: 245 KESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDR 304
+E +++ +EK+ E E++ E + +EK E ++ + E M EEK R
Sbjct: 500 QEKKIREQEEKI-----REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554
Query: 305 KIE-DLRQCLNRYKKMQD 321
+ E LRQ + +KMQ+
Sbjct: 555 EQEVRLRQ---QEEKMQE 569
Score = 59.3 bits (142), Expect = 2e-08
Identities = 63/257 (24%), Positives = 127/257 (49%), Gaps = 36/257 (14%)
Query: 100 DVYQERLARLENDKESLVLQVSVLTDQ-VEAQGEKIRDLEFCLEEHREKVNATEEMLQQE 158
D Y E L + E D SL L + +TD+ ++ + K+++ +E + ++ + L+++
Sbjct: 180 DRYIEELTK-ERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRK 238
Query: 159 L------LSRTSLETQKLDLMAEISNLKLKLTA-VEKDRL------DYEDKFRDTEGLIQ 205
L L + L+ + L E+ ++ KL A VE++ L E+K E IQ
Sbjct: 239 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ 298
Query: 206 E----INDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMK 261
E I + K+ E + + + E+ + ++++ +E + EKE +++ L+EK+
Sbjct: 299 EREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM----- 353
Query: 262 GEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQD 321
E +I +++E K+ +E+ I Q+ ++ E+ M EEK R+ E+ K+++
Sbjct: 354 HEQEKIREQEE---KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE---------KIRE 401
Query: 322 TVVLAQGKKGKDGEYEE 338
+ Q ++ K GE EE
Sbjct: 402 QEEMMQEQEEKMGEQEE 418
Score = 57.8 bits (138), Expect = 5e-08
Identities = 38/164 (23%), Positives = 85/164 (51%), Gaps = 7/164 (4%)
Query: 100 DVYQERLARLENDKESLVLQVSVLTDQVEA---QGEKIRDLEFCLEEHREKVNATEEMLQ 156
++ QE+ ++ +E + Q + +Q E Q EKIR+ E + E EK+ EEM+Q
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 463
Query: 157 QELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQE----INDLRL 212
++ E + + A++ + K+ E+ + E K R+ E I+E + +
Sbjct: 464 EQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 523
Query: 213 KVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKL 256
K+ E + + + E+K++ ++++ +E++ E+E +++ +EK+
Sbjct: 524 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKM 567
Score = 53.1 bits (126), Expect = 1e-06
Identities = 58/264 (21%), Positives = 127/264 (48%), Gaps = 23/264 (8%)
Query: 49 LHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLAR 108
L LVE + +++ + K L A+ L+ Q Q HL G Q A+
Sbjct: 218 LQLVESEKSEIQLNVKELKRKLE------RAKLLLPQQQLQAEADHL---GKELQSVSAK 268
Query: 109 LENDKESLVLQVSVLTDQVEA---QGEKIRDLEFCLEEHREKVNATEEML--QQELLSRT 163
L+ E L + Q E Q EKI++ E ++E EK+ EE + Q+E++
Sbjct: 269 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEK 328
Query: 164 SLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRL--KVSEMDSER 221
+ ++ + M K++ ++++ ++K R+ E QE +R K E +++
Sbjct: 329 EEKMRRQEEMMWEKEEKIREL---EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 385
Query: 222 LQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEK 281
+ E+K++ ++++ +E ++E+E ++ +EK+ + + E E ++ ++K++E+
Sbjct: 386 WRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM-WEQEEEMQEQEEKMRRQEEKIREQ 444
Query: 282 NIEVQKMKKAV---ESLMAANEEK 302
++++ ++ + E +M EEK
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEK 468
Score = 48.1 bits (113), Expect = 4e-05
Identities = 65/303 (21%), Positives = 140/303 (46%), Gaps = 20/303 (6%)
Query: 54 DLRGLLEMMETDEKEGLRCQIPDSTAET---LVEWLQSQMTNGHLPGNGDVYQERLARLE 110
+L L + T +K+ R I + T E +E ++ +T+ L QE+L +E
Sbjct: 164 ELEQALSAVATQKKKADR-YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVE 222
Query: 111 NDKESLVLQVSVLTDQVEAQGEKIRDLEFCLE-----EHREKVNAT--EEMLQQELLSRT 163
++K + L V L ++E + + E + + V+A ++ + EL +R
Sbjct: 223 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 282
Query: 164 SLETQKLDLMAE--ISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSER 221
+ + ++ E I + K+ E+ + E+K R E ++ E + + EM E+
Sbjct: 283 NQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 342
Query: 222 LQYEKKLKSTKDELASLKEQLEEKESEVK-RLQEKLV---CKMKGEGVEIVDRDENFKKK 277
+ ++L+ E ++EQ E+++ E K R QEK KM + +I +++E +++
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402
Query: 278 LKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYE 337
+ + +KM + E + EE + E +R+ + +K+++ + ++ K E E
Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR---QEEKIREQEKKIREQEEKIREQE 459
Query: 338 ELL 340
E++
Sbjct: 460 EMM 462
Score = 37.0 bits (84), Expect = 0.093
Identities = 26/110 (23%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Query: 100 DVYQERLARLENDKESLVLQVSVLTDQVEA---QGEKIRDLEFCLEEHREKVNATEEMLQ 156
++ QE+ ++ + + Q + + +Q E Q EKIR+ E + E EK+ EEM+Q
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 519
Query: 157 QELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQE 206
++ E + + ++ + K+ E+ + E + R E +QE
Sbjct: 520 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 63.5 bits (153), Expect = 9e-10
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 11/204 (5%)
Query: 104 ERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRT 163
E +A+L +K++L D ++ + +K+ L + ++V+ E L+QE R
Sbjct: 989 EIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRM 1048
Query: 164 SLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQ 223
LE K L ++ + + +E D+L E+K + E +IN K+ + LQ
Sbjct: 1049 DLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKE---FDINQQNSKIEDEQVLALQ 1105
Query: 224 YEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFK-------K 276
+KKLK + + L+E+L E E + EKL + E EI +R E +
Sbjct: 1106 LQKKLKENQARIEELEEEL-EAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1164
Query: 277 KLKEKNIEVQKMKKAVESLMAANE 300
K++ E QKM++ +E +E
Sbjct: 1165 MNKKREAEFQKMRRDLEEATLQHE 1188
Score = 54.3 bits (129), Expect = 6e-07
Identities = 80/357 (22%), Positives = 141/357 (39%), Gaps = 56/357 (15%)
Query: 6 SDMLAAALEQMDGIIAGSKALEYSNGIF--DCQSPTSPFMGSLRALHLVEDLRGLLEMME 63
+D +A EQ+D + + LE F + TS ++A +E + LE
Sbjct: 1199 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQA 1258
Query: 64 TDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVL 123
+ + L + S + + + Q NG L + + +++L K S Q+ L
Sbjct: 1259 NEYRVKLE-EAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDL 1317
Query: 124 TDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQE---------LLS---------RTSL 165
Q+E +G+ L L+ R + E ++E +LS RT
Sbjct: 1318 KRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY 1377
Query: 166 ETQKLDLMAEISNLKLKLT--------AVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEM 217
ET + E+ K KL AVE + L EI DL + V
Sbjct: 1378 ETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERS 1437
Query: 218 DSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKL------VCKMKGEGVEIVDRD 271
++ +KK ++ LA K++ EE +SE++ Q++ + K+K E ++
Sbjct: 1438 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1497
Query: 272 ENFKKKLKE----------------KNI-EVQKMKKAVE----SLMAANEEKDRKIE 307
E FK++ K KN+ E++K++K +E L +A EE + +E
Sbjct: 1498 ETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLE 1554
Score = 53.9 bits (128), Expect = 7e-07
Identities = 63/286 (22%), Positives = 118/286 (41%), Gaps = 42/286 (14%)
Query: 100 DVYQERLARLENDKESLVLQVSVLTDQVE------AQGEKI-RDLEFCLEEHREKVNATE 152
D Q +LE +K L++ +T +E A EK+ R LE E+R K+ +
Sbjct: 1210 DNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQ 1269
Query: 153 EMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRL 212
L R L+T+ +L ++ + ++ + + +L Y Q++ DL+
Sbjct: 1270 RSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSY----------TQQMEDLKR 1319
Query: 213 KVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGE--------- 263
++ E + L+S + + L+EQ EE E+E K ++++ K E
Sbjct: 1320 QLEEEGKAKNALAHALQSARHDCDLLREQYEE-ETEAKAELQRVLSKANSEVAQWRTKYE 1378
Query: 264 --GVEIVDRDENFKKKLKEKNIEVQKMKKAV----ESLMAANEEKDRKIEDLRQCLNR-- 315
++ + E KKKL ++ + ++ +AV SL +IEDL + R
Sbjct: 1379 TDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438
Query: 316 -------YKKMQDTVVLAQGKKGKDGEYEELLNSSSISSLLDAQGF 354
K+ +LA+ K+ + EL +S + L + F
Sbjct: 1439 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELF 1484
Score = 53.1 bits (126), Expect = 1e-06
Identities = 52/249 (20%), Positives = 116/249 (46%), Gaps = 35/249 (14%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR 162
+E R++ E + L +++ + ++ DL+ ++ ++ +N EE Q + ++
Sbjct: 855 KEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNK 914
Query: 163 TSLETQKLDLMAEISN---LKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDS 219
LE + ++ + + + +LTA ++ D + L ++I+DL L +++++
Sbjct: 915 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLED------ECSELKKDIDDLELTLAKVEK 968
Query: 220 ERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLK 279
E+ E K+K+ +E+A L E + + E K LQE ++ L
Sbjct: 969 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA------------------HQQALD 1010
Query: 280 EKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEEL 339
+ +E K V SL + + +++++DL L + KK++ + L + K+ +G+ +
Sbjct: 1011 DLQVEEDK----VNSLSKSKVKLEQQVDDLEGSLEQEKKVR--MDLERAKRKLEGDLK-- 1062
Query: 340 LNSSSISSL 348
L SI L
Sbjct: 1063 LTQESIMDL 1071
Score = 52.4 bits (124), Expect = 2e-06
Identities = 52/218 (23%), Positives = 100/218 (45%), Gaps = 23/218 (10%)
Query: 108 RLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLET 167
RL+N+ E L++ V A +K R+ + L E ++K ++ L+ SL T
Sbjct: 1422 RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLST 1481
Query: 168 QKLDLMAEISNLKLKLTAVEKDRLDYEDKF-RDTEGLIQEINDLRLKVSEMDSERLQYEK 226
+ KL ++ L++ + F R+ + L +EI+DL ++ E + EK
Sbjct: 1482 ELF-----------KLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK 1530
Query: 227 KLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQ 286
K + E L+ LEE E+ ++ + K++ +E ++KL EK+ E++
Sbjct: 1531 VRKQLEVEKLELQSALEEAEASLEHEEGKILRAQ----LEFNQIKAEIERKLAEKDEEME 1586
Query: 287 KMK----KAVESLMAANEEKDRKIEDLRQCLNRYKKMQ 320
+ K + V+SL + + + R ++ L KKM+
Sbjct: 1587 QAKRNHQRVVDSLQTSLDAETRSRNEV---LRVKKKME 1621
Score = 44.3 bits (103), Expect = 6e-04
Identities = 39/143 (27%), Positives = 70/143 (48%), Gaps = 19/143 (13%)
Query: 225 EKKLKSTKDELASLKEQLEEKESEVKRLQEKLV----------CKMKGEGVEIVDRDENF 274
EK++ + K+E +KE LE+ E+ K L+EK+V +++ E + D +E
Sbjct: 848 EKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC 907
Query: 275 KKKLKEK---NIEVQKMKKAVESLMAANEE---KDRKIEDLRQCLNRYKKMQD-TVVLAQ 327
+ +K K +V++M + +E N E K RK+ED +C K + D + LA+
Sbjct: 908 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLED--ECSELKKDIDDLELTLAK 965
Query: 328 GKKGKDGEYEELLNSSSISSLLD 350
+K K ++ N + + LD
Sbjct: 966 VEKEKHATENKVKNLTEEMAGLD 988
Score = 43.9 bits (102), Expect = 8e-04
Identities = 55/268 (20%), Positives = 116/268 (43%), Gaps = 43/268 (16%)
Query: 100 DVYQERLARLENDK---ESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQ 156
+ Y+E L LE K ++L ++S LT+Q+ G+ + +L EKV
Sbjct: 1488 NAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHEL--------EKV-------- 1531
Query: 157 QELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSE 216
R LE +KL+L + + + L E L + +F + I+ K++E
Sbjct: 1532 -----RKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER------KLAE 1580
Query: 217 MDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKK 276
D E Q ++ + D L + + +EV R+++ KM+G+ E+ + + +
Sbjct: 1581 KDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKK----KMEGDLNEMEIQLSHANR 1636
Query: 277 KLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTV---------VLAQ 327
E +V+ ++ ++ ++ R +DL++ + ++ + + V+ Q
Sbjct: 1637 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1696
Query: 328 GKKGKDGEYEELLNSSSISSLLDAQGFS 355
++ + +EL+ +S LL +Q S
Sbjct: 1697 TERSRKLAEQELIETSERVQLLHSQNTS 1724
Score = 35.8 bits (81), Expect = 0.21
Identities = 44/227 (19%), Positives = 101/227 (44%), Gaps = 37/227 (16%)
Query: 108 RLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHR----EKVNATEEMLQQELLSRT 163
++E D + +Q+S ++++ L+ L++ + + V A +++ + +
Sbjct: 1619 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAI--- 1675
Query: 164 SLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQ 223
+E + L AE+ L+ + E+ R E + +T +Q ++ ++ +
Sbjct: 1676 -VERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHS-------QNTSLIN 1727
Query: 224 YEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNI 283
+KK++S +L L+ ++EE E + +E K K + E KK+ ++ +
Sbjct: 1728 QKKKMES---DLTQLQSEVEEAVQECRNAEE----KAKKAITDAAMMAEELKKE-QDTSA 1779
Query: 284 EVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKK 330
+++MKK +E + I+DL+ L+ + + L GKK
Sbjct: 1780 HLERMKKNME----------QTIKDLQHRLDE----AEQIALKGGKK 1812
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 63.2 bits (152), Expect = 1e-09
Identities = 53/218 (24%), Positives = 103/218 (47%), Gaps = 14/218 (6%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR 162
QERL + +SL L++ L +Q++A EK ++LE + + + Q ++
Sbjct: 65 QERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIA-------IQSQFTRTK 117
Query: 163 TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERL 222
LE +K DL+ L +L + +D +K +++ E L+LK+ E+ + +
Sbjct: 118 EELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGE---LQLKLDELQASDV 174
Query: 223 QYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKN 282
+ + K + E L Q +E+K ++L+ + +G EI++ K L+ K
Sbjct: 175 SVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILE----LKCNLENKK 230
Query: 283 IEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQ 320
EV ++++ + L +NE + +EDL L K+ Q
Sbjct: 231 EEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQ 268
Score = 55.1 bits (131), Expect = 3e-07
Identities = 125/638 (19%), Positives = 248/638 (38%), Gaps = 113/638 (17%)
Query: 63 ETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNG-DVYQERLARLENDKESLVLQVS 121
E EK G+ E + W + N HL D E +L ++KE ++
Sbjct: 1313 ELSEKSGMLQAEKKLLEEDVKRW---KARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQ 1369
Query: 122 VLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKL 181
LT+++ +I L ++ + + +E L + RT ET + DL A+I +++
Sbjct: 1370 QLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKV---RTEKETIQKDLDAKIIDIQE 1426
Query: 182 K---LTAVEKDRLDYEDKFRDTEGLIQEI-----------NDLRLKVSEMDS--ERL-QY 224
K +T V+K Y+ ++ + + ++ + + V EM E L Q
Sbjct: 1427 KVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQA 1486
Query: 225 EKKLKSTKDELASLKEQLEEKESEVKRLQEKLV------CKMKGEGVEIVDRDENFKKKL 278
E K KS + ++ +L++ L EKE+E + LQE+ V +++ + + ++E ++++
Sbjct: 1487 ETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQI 1546
Query: 279 KEKNIEVQK----MKKAVESLMAANEEKDRKIEDLRQ---CLNRYKKMQDTVVLA----- 326
EK + +K K + L ++ ++ E+L+Q L++ K D + A
Sbjct: 1547 TEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQY 1606
Query: 327 ---------QGKKGKDGEYEELLNSSSISSLLDAQ---------------GFSDLEKSPS 362
+ ++ ++ E+ S+ + Q G + P+
Sbjct: 1607 EGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIASTSDPPT 1666
Query: 363 ----PTPVMGSPSCDPFNTSVPEEFHTTILQVSI-PSLLPATVSMETSEKSKLTPKPETS 417
PTPV+ +PS T+ + + + SI P + PATV+ T+ + T P T
Sbjct: 1667 ANIKPTPVVSTPS---KVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPT-ATVMPTTQ 1722
Query: 418 FE-----ENDGNI----ILGAT----------VDTQLCDKLLTSSLQKSSS--------- 449
E +++G + + G+T V + +LT Q ++
Sbjct: 1723 VESQEAMQSEGPVEHVPVFGSTSGSVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQS 1782
Query: 450 ---LGNLKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQ--DTSMDDNPFGTRKV 504
+ +E S E +Q + +R + FGT+ P + ++ T +
Sbjct: 1783 HPQIEPANQELSSNIVEVVQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTIEA 1842
Query: 505 RSSFGRGFFKIKSNKRTASAPNLDRKRSASAPTLAETEKETAEHLDLAGASSRPKDSQRN 564
++ K+ S + + A + E ET + + S +Q +
Sbjct: 1843 SDQVSDDTVEMPLPKKLKSVTPVGTEEEVMAEESTDGEVETQVYNQDSQDSIGEGVTQGD 1902
Query: 565 SPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTTFNPDD 602
P DS++ S+ + G L+ Q TT + D
Sbjct: 1903 Y-----TPMEDSEETSQSLQIDLGPLQSDQQTTTSSQD 1935
Score = 51.6 bits (122), Expect = 4e-06
Identities = 52/223 (23%), Positives = 102/223 (45%), Gaps = 12/223 (5%)
Query: 101 VYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELL 160
V + R L+ +KE L L L+ Q E+ + R L + + + E + E
Sbjct: 776 VAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLT-NLQTIQGILERSETETK 834
Query: 161 SRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSE 220
R S + +KL+ EIS+LK KL + E + T L ++ D + ++ +
Sbjct: 835 QRLSSQIEKLE--HEISHLKKKLEN------EVEQRHTLTRNLDVQLLDTKRQLDTETNL 886
Query: 221 RLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKE 280
L ++ LK+ + E+A+LK+ L E +V + K + E VD + +L++
Sbjct: 887 HLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVD---DLVSQLRQ 943
Query: 281 KNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTV 323
+V +K+ +++ + E+ + L + LN+ K++ + V
Sbjct: 944 TEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEV 986
Score = 50.4 bits (119), Expect = 8e-06
Identities = 70/312 (22%), Positives = 142/312 (45%), Gaps = 43/312 (13%)
Query: 52 VEDLRGLLEMMETDEKEGLRCQIPDSTAET--LVEWLQSQMTNGH-LPGNGDVY------ 102
++ ++G+LE ET+ K+ L QI E L + L++++ H L N DV
Sbjct: 819 LQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKR 878
Query: 103 -------------------QERLARLENDKESLVLQVSVLTDQVEAQG-----EKIRDLE 138
Q+ +A L+ ++ +QV+ + Q +G E + DL
Sbjct: 879 QLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLV 938
Query: 139 FCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFR 198
L + E+VN +E L+ S +++E + + + +L + E+ R + E + +
Sbjct: 939 SQLRQTEEQVNDLKERLK---TSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLK 995
Query: 199 DTEGLIQEINDLRLKVSEMDSERLQYEKK--LKSTKDELASLKEQLEEKESEVKRLQEKL 256
++ ++ ++V E + + LQ +K+ ++S + +L+ LK+ L ++EV+ ++
Sbjct: 996 ESAEFQTQLEKKLMEV-EKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRA 1054
Query: 257 VCKMKGEGVEIVDRDENFKKKLKEKN-IEVQKMKKA--VESLMAANEEKDRKIEDLRQCL 313
+ E D E K ++ +N E + M A VE+L AA E+ K+ +RQ L
Sbjct: 1055 STALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVS-KMASVRQHL 1113
Query: 314 NRYKKMQDTVVL 325
+ ++ +L
Sbjct: 1114 EETTQKAESQLL 1125
Score = 48.5 bits (114), Expect = 3e-05
Identities = 51/243 (20%), Positives = 110/243 (45%), Gaps = 16/243 (6%)
Query: 100 DVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQEL 159
+V Q R E L ++ L D + A+ EK++ + +H E + TE M +
Sbjct: 1215 EVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETM-NVVM 1273
Query: 160 LSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYED---KFRDTEGLIQEINDLRLKVSE 216
+ L +K L ++ ++ K+ +E D L ++ + + G++Q + +L +
Sbjct: 1274 ETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQA--EKKLLEED 1331
Query: 217 MDSERLQYEKKLKSTKD-ELASLKEQLEEKESEVKRLQE--KLVCKMKGE---GVEIVDR 270
+ + + + + KD + ++ L EKE KR+Q+ + + ++K E +
Sbjct: 1332 VKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTN 1391
Query: 271 DENFKKKLKEKNIEVQKMKKAVESLMAAN----EEKDRKIEDLRQCLNRYKKMQDTVVLA 326
++N + LKE +V+ K+ ++ + A +EK + I +++ RYK + +
Sbjct: 1392 NQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQ 1451
Query: 327 QGK 329
Q K
Sbjct: 1452 QDK 1454
Score = 38.9 bits (89), Expect = 0.025
Identities = 76/357 (21%), Positives = 139/357 (38%), Gaps = 93/357 (26%)
Query: 60 EMMETDEKEGLRCQIPDSTAETLVEWL-QSQMTNGHLPGNGDVYQE-------RLARLEN 111
+++ T+E+ + + L E L +S T G L D Q R RLE
Sbjct: 126 DLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQ 185
Query: 112 DKESLVLQVSVL-------TDQVEA----QGEKIRDLEFCLEEHREKVNATEEMLQQELL 160
+KE L Q + L TD++ A +G +I +L+ LE +E+V+ EE +
Sbjct: 186 EKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKT 245
Query: 161 SRTSLETQKLDLMAEISNLK-----------------LKLTAVEKDRLD-YEDKFRDTEG 202
S L+ DL+ ++ K +KL+ + K D E K +
Sbjct: 246 SNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTR 305
Query: 203 LIQEINDLRLKVSE------------------MDSERLQ----YEKKLKSTKDELASLKE 240
++E++ L + E M+ E L+ EK+L++ D L++ K
Sbjct: 306 AVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKR 365
Query: 241 Q---LEEKESEVKRLQEKLVCKMKGEGVEIVD--------RDENFKKKLKEKNI------ 283
+ L E+E V K+ G+++ + +D+ +KL+ K I
Sbjct: 366 KGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDE 425
Query: 284 -----------------EVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTV 323
E ++ +KAV SL E+ ++I+ L++ ++ K +
Sbjct: 426 IVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVL 482
Score = 38.1 bits (87), Expect = 0.042
Identities = 45/219 (20%), Positives = 103/219 (47%), Gaps = 26/219 (11%)
Query: 145 REKVNATEEMLQQELLS-RTSLETQKLDLMAEISNLKLKLTAVEK-DRLDYEDKFRDTEG 202
R+ + T + + +LL + S E ++ L E+S + +EK +RL ++ + ++
Sbjct: 1110 RQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDK 1169
Query: 203 LIQEIND-----LRLKVSEMDSERLQY---------EKKLKSTKDELASL-----KEQLE 243
++ + + L + +SE + Q EK++ T+ E+A + ++++E
Sbjct: 1170 VVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVE 1229
Query: 244 EKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKD 303
E E++ LQ+ L + E V++ + ++L +K + M +E+ EEK+
Sbjct: 1230 LLERELQELQDSL--NAEREKVQVTAKTMAQHEELMKKT---ETMNVVMETNKMLREEKE 1284
Query: 304 RKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNS 342
R +DL+Q + +K++ ++ Q + E +L +
Sbjct: 1285 RLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQA 1323
Score = 35.8 bits (81), Expect = 0.21
Identities = 52/234 (22%), Positives = 105/234 (44%), Gaps = 19/234 (8%)
Query: 98 NGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQ- 156
N +V + A + E +++V ++ E Q +K R +E +E+ ++ T +Q
Sbjct: 989 NIEVRLKESAEFQTQLEKKLMEVE--KEKQELQDDKRRAIE-SMEQQLSELKKTLSSVQN 1045
Query: 157 --QELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKV 214
QE L R S + K+ +++ + E + ++ + + +V
Sbjct: 1046 EVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAAD--VEALQAAKEQV 1103
Query: 215 SEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENF 274
S+M S R E+ + + +L K EE+E +K K VC+ E +E +R +
Sbjct: 1104 SKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRC--EDLEKQNRLLHD 1161
Query: 275 K-KKLKEKNIEVQKMKKAVE-----SLMAANEEKDRKIEDLRQCLNRYKKMQDT 322
+ +KL +K V +K+ V+ SL + +++ +E LR + R K++ +T
Sbjct: 1162 QIEKLSDK--VVASVKEGVQGPLNVSLSEEGKSQEQILEILR-FIRREKEIAET 1212
Score = 35.0 bits (79), Expect = 0.35
Identities = 60/311 (19%), Positives = 127/311 (40%), Gaps = 42/311 (13%)
Query: 51 LVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLE 110
+V+++ +++ +E R Q + A V+ Q+ L + D ++ + LE
Sbjct: 426 IVKEVEAKAPILKRQREEYERAQ--KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLE 483
Query: 111 NDKESLVLQVSVLTDQV--------EAQGEK-IRDLEFC----------LEEHREKVNAT 151
D + +QV L+ Q+ EA+G IRD E + +H
Sbjct: 484 RDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNI 543
Query: 152 EEMLQQEL--------LSRTSLETQKLDLMAEISNLKLKL----TAVEKDRLDYEDKFRD 199
EE+ QQ L T ++ ++I+ L+LKL T +E+ R + + +
Sbjct: 544 EELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQL 603
Query: 200 TEGLIQEINDLRLKVSEMDSERLQY------EKKLKSTKDELASLKEQLEEKESEVKRLQ 253
+ ++++ + R+ +S+ + + L ST ++ Q + V ++
Sbjct: 604 VDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPST--SQTVSTPAPVPVIE 661
Query: 254 EKLVCKMKGEGVEIVDRDENFKK-KLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQC 312
+ K ++ + EN+KK K + + I+ ++++K E + + + L
Sbjct: 662 STEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFA 721
Query: 313 LNRYKKMQDTV 323
RY+ +QD V
Sbjct: 722 SKRYEMLQDNV 732
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 62.8 bits (151), Expect = 2e-09
Identities = 62/281 (22%), Positives = 131/281 (46%), Gaps = 20/281 (7%)
Query: 93 GHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATE 152
G L + + Q L +L+ + L ++ +E Q + +LE +++
Sbjct: 1412 GDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAH 1471
Query: 153 EMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRL 212
E Q+E L R L+ +K L+AE +LK +L E+K D G Q++ L
Sbjct: 1472 EEAQREKLQREKLQREKDMLLAEAFSLKQQL----------EEKDMDIAGFTQKVVSLEA 1521
Query: 213 KVSEMDSERLQYEKKLKSTKDEL----ASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIV 268
++ ++ S+ + E L K +L A +K+Q EE + + +Q K++ E +E+
Sbjct: 1522 ELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLE-MEME 1580
Query: 269 DRDENFKKKLKEKNIEVQKMKKAVESLMAANE-EKDRKIEDLRQCLNRYKKMQDTV-VLA 326
+ K+++ ++ EV++ +++ + + E + + + ED ++ L ++++ + L+
Sbjct: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLS 1640
Query: 327 QGKKGKDGEYEELLNSS---SISSLLDAQGFSDLEKSPSPT 364
+D E E+ L + + L DAQ D K+ +P+
Sbjct: 1641 DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS 1681
Score = 50.1 bits (118), Expect = 1e-05
Identities = 49/235 (20%), Positives = 108/235 (45%), Gaps = 46/235 (19%)
Query: 126 QVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTA 185
+V+ E+IR+ + +++ R K+ E+ + L+ LE++ +L +E+++
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTD------- 1300
Query: 186 VEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEK 245
E++ + + D E +ERL+ EK++K + + +LK+Q+E
Sbjct: 1301 -ERNTGESASQLLDAE----------------TAERLRAEKEMKELQTQYDALKKQMEVM 1343
Query: 246 ESEVKRLQEKLVCKMKGE----------------GVEIVD-----RDENFKKKLKEKNIE 284
E EV + ++ GE V VD + F+ KL+ +
Sbjct: 1344 EMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN 1403
Query: 285 VQKMKKAVESLMAANEEKDRKIEDL-RQCLNRYKKMQDTVVLAQGKKGKDGEYEE 338
+++++ + L A +EE R ++ L ++C ++QDT + +G++ ++ E E+
Sbjct: 1404 KRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
Score = 47.8 bits (112), Expect = 5e-05
Identities = 63/304 (20%), Positives = 135/304 (44%), Gaps = 46/304 (15%)
Query: 88 SQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREK 147
+Q+ HL + +E +A+L+N E + +A +I DL +++ +
Sbjct: 1668 AQLMLDHLKNSAPSKRE-IAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKA 1726
Query: 148 VNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEI 207
A EE L + + ++ + + +++ L ++K + RD + +I
Sbjct: 1727 KTALEEQLSRLQREKNEIQNRLEEDQEDMNEL------MKKHKAAVAQASRD----LAQI 1776
Query: 208 NDLRLKVSEMDSERLQYEKKLKSTKDE--------------------LASLKEQLEEKES 247
NDL+ ++ E + E+ + ++KL++ + + + L+ +LE + +
Sbjct: 1777 NDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERT 1836
Query: 248 EVKRLQEKLVCKMKGEGVEIV--DRDENF--KKKLKEKNIEVQKM----KKAVESLMAAN 299
+VKRL E L ++K E +E + +RD+ + + KE+N +Q+ K+ + L
Sbjct: 1837 QVKRL-ESLASRLK-ENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKE 1894
Query: 300 EEKDRKIEDLRQCLNRY----KKMQDTVVLAQGKKGK-DGEYEELLNSSSISSLLDAQGF 354
E RK +L L + +Q + LA + G E+ + S L++++G
Sbjct: 1895 AEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGD 1954
Query: 355 SDLE 358
SD++
Sbjct: 1955 SDVD 1958
Score = 46.2 bits (108), Expect = 2e-04
Identities = 46/227 (20%), Positives = 103/227 (45%), Gaps = 21/227 (9%)
Query: 86 LQSQMTNGHLPGNGDVYQERLARLEN-DKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEH 144
++ Q++ + + Q+ ++LE +KE L+++ +D++E+ +I +L L +
Sbjct: 1247 IEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLN--SDRLES---RISELTSELTDE 1301
Query: 145 REKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLI 204
R + ++L E R E + +L + LK ++ +E + + E +
Sbjct: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVM---------EARL 1352
Query: 205 QEINDLRLKVSEMDSE---RLQYEKKLKSTKDELASLKEQLEEK---ESEVKRLQEKLVC 258
++ +V + D+ RL+YE+ ++ L+++ E+K E + KR E+ +
Sbjct: 1353 IRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLG 1412
Query: 259 KMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRK 305
++ + E + KKK + E+Q K +E N E ++K
Sbjct: 1413 DLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 62.8 bits (151), Expect = 2e-09
Identities = 62/281 (22%), Positives = 131/281 (46%), Gaps = 20/281 (7%)
Query: 93 GHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATE 152
G L + + Q L +L+ + L ++ +E Q + +LE +++
Sbjct: 1412 GDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAH 1471
Query: 153 EMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRL 212
E Q+E L R L+ +K L+AE +LK +L E+K D G Q++ L
Sbjct: 1472 EEAQREKLQREKLQREKDMLLAEAFSLKQQL----------EEKDMDIAGFTQKVVSLEA 1521
Query: 213 KVSEMDSERLQYEKKLKSTKDEL----ASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIV 268
++ ++ S+ + E L K +L A +K+Q EE + + +Q K++ E +E+
Sbjct: 1522 ELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLE-MEME 1580
Query: 269 DRDENFKKKLKEKNIEVQKMKKAVESLMAANE-EKDRKIEDLRQCLNRYKKMQDTV-VLA 326
+ K+++ ++ EV++ +++ + + E + + + ED ++ L ++++ + L+
Sbjct: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLS 1640
Query: 327 QGKKGKDGEYEELLNSS---SISSLLDAQGFSDLEKSPSPT 364
+D E E+ L + + L DAQ D K+ +P+
Sbjct: 1641 DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS 1681
Score = 50.1 bits (118), Expect = 1e-05
Identities = 49/235 (20%), Positives = 108/235 (45%), Gaps = 46/235 (19%)
Query: 126 QVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTA 185
+V+ E+IR+ + +++ R K+ E+ + L+ LE++ +L +E+++
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTD------- 1300
Query: 186 VEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEK 245
E++ + + D E +ERL+ EK++K + + +LK+Q+E
Sbjct: 1301 -ERNTGESASQLLDAE----------------TAERLRAEKEMKELQTQYDALKKQMEVM 1343
Query: 246 ESEVKRLQEKLVCKMKGE----------------GVEIVD-----RDENFKKKLKEKNIE 284
E EV + ++ GE V VD + F+ KL+ +
Sbjct: 1344 EMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN 1403
Query: 285 VQKMKKAVESLMAANEEKDRKIEDL-RQCLNRYKKMQDTVVLAQGKKGKDGEYEE 338
+++++ + L A +EE R ++ L ++C ++QDT + +G++ ++ E E+
Sbjct: 1404 KRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
Score = 47.8 bits (112), Expect = 5e-05
Identities = 75/396 (18%), Positives = 166/396 (41%), Gaps = 49/396 (12%)
Query: 88 SQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREK 147
+Q+ HL + +E +A+L+N E + +A +I DL +++ +
Sbjct: 1668 AQLMLDHLKNSAPSKRE-IAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKA 1726
Query: 148 VNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEI 207
A EE L + + ++ + + +++ L ++K + RD + +I
Sbjct: 1727 KTALEEQLSRLQREKNEIQNRLEEDQEDMNEL------MKKHKAAVAQASRD----LAQI 1776
Query: 208 NDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEI 267
NDL+ ++ E + E+ + ++KL++ + ++ L++ + +K LV + + + E+
Sbjct: 1777 NDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDK---------SLVSRQEAKIREL 1827
Query: 268 VDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQ 327
R E + ++K ++K+ +E L EE+D++I + + K++Q +
Sbjct: 1828 ETRLEFERTQVKRLESLASRLKENMEKL---TEERDQRIAAENREKEQNKRLQRQL---- 1880
Query: 328 GKKGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTI 387
+ E EL + +S + DLE S + N S+ +
Sbjct: 1881 --RDTKEEMGELARKEAEASRKKHELEMDLE------------SLEAANQSLQADLKLAF 1926
Query: 388 LQVSIPSLLPATV--SMETSEKSKLTPKPE---TSFEENDGNIILGATVDTQLCDKLLTS 442
++ L A + ME+ E L + T +++ + + VD++L D++
Sbjct: 1927 KRIGD---LQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGV 1983
Query: 443 SLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESR 478
S + G K + DG ++ TS ++ A R
Sbjct: 1984 KSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDR 2019
Score = 46.2 bits (108), Expect = 2e-04
Identities = 46/227 (20%), Positives = 103/227 (45%), Gaps = 21/227 (9%)
Query: 86 LQSQMTNGHLPGNGDVYQERLARLEN-DKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEH 144
++ Q++ + + Q+ ++LE +KE L+++ +D++E+ +I +L L +
Sbjct: 1247 IEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLN--SDRLES---RISELTSELTDE 1301
Query: 145 REKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLI 204
R + ++L E R E + +L + LK ++ +E + + E +
Sbjct: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVM---------EARL 1352
Query: 205 QEINDLRLKVSEMDSE---RLQYEKKLKSTKDELASLKEQLEEK---ESEVKRLQEKLVC 258
++ +V + D+ RL+YE+ ++ L+++ E+K E + KR E+ +
Sbjct: 1353 IRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLG 1412
Query: 259 KMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRK 305
++ + E + KKK + E+Q K +E N E ++K
Sbjct: 1413 DLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 62.0 bits (149), Expect = 3e-09
Identities = 65/232 (28%), Positives = 110/232 (47%), Gaps = 22/232 (9%)
Query: 100 DVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATE---EMLQ 156
D + RL E Q+ + ++ Q +I DL+ L+ KVN + E LQ
Sbjct: 525 DALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQ 584
Query: 157 QELLSR----TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGL-IQEINDLR 211
++L + +SL+ + L A+ +N LT +E+ +K R E L Q D R
Sbjct: 585 EQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEE---ALAEKERTIERLKEQRDRDER 641
Query: 212 LKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRD 271
K E+D+ Y+K LK K++++ L+ L EKE+ + L+E + G++ R
Sbjct: 642 EKQEEIDN----YKKDLKDLKEKVSLLQGDLSEKEASLLDLKEH-ASSLASSGLKKDSRL 696
Query: 272 ENFKKKLKEKNIEVQKM----KKAVESLM--AANEEKDRKIEDLRQCLNRYK 317
+ + L++K E KM KKA E+ + A+ E +I+ L + + RYK
Sbjct: 697 KTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK 748
Score = 55.5 bits (132), Expect = 3e-07
Identities = 60/234 (25%), Positives = 105/234 (44%), Gaps = 27/234 (11%)
Query: 104 ERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEF-----------CLEEHREK---VN 149
E L +EN+K +++ L QV+ Q +K+ +L+ LEE R + +N
Sbjct: 763 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLN 822
Query: 150 ATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEIND 209
+ + LQ L + +++ + E +++TA + L E+ R +++ +
Sbjct: 823 DSSQQLQDSLRKKDD----RIEELEEALRESVQITAEREMVLAQEESARTNAE--KQVEE 876
Query: 210 LRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEV-KRLQEKLVCKMKGEGVEIV 268
L + + ++ E + KL ST+ LA + L +E K L+E L K + I
Sbjct: 877 LLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAIS 936
Query: 269 DRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLR-QCLNRYKKMQD 321
++D N L E + KK E + A EKDR ++ L+ Q NR K M D
Sbjct: 937 EKDANIA--LLELS---SSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMAD 985
Score = 53.9 bits (128), Expect = 7e-07
Identities = 68/322 (21%), Positives = 136/322 (42%), Gaps = 67/322 (20%)
Query: 53 EDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPG--------NGDVYQE 104
E ++ LLEM+++ +GL + + E +++M HL N + +E
Sbjct: 307 ESIKKLLEMLQS---KGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREE 363
Query: 105 RLARLENDKES-----LVLQVSVLTDQVEAQGEKIRDLE-----------FCLEEHREKV 148
R EN +S L + + ++ + +RDLE EE E++
Sbjct: 364 MHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEM 423
Query: 149 NATE-------------EMLQQELLSRTS----LETQKLDLMAEISNLKLKLTAVEKDRL 191
E E L++EL S+ + L+ + L AEI +K +L+ + + L
Sbjct: 424 KQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELL 483
Query: 192 DYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKES---- 247
+ K E L + +D + + + E++ + E+ +L+ +LEEKE+
Sbjct: 484 ALQTKL---ETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK 540
Query: 248 EVKRLQE---------------KLVCKMKGEGVEIVDRD-ENFKKKLKEKNIEVQKMKKA 291
+ K++Q+ K + +K V ++ + EN +++L++K ++ +K+
Sbjct: 541 KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER 600
Query: 292 VESLMAANEEKDRKIEDLRQCL 313
V+SL A D + L + L
Sbjct: 601 VKSLQADTTNTDTALTTLEEAL 622
Score = 47.8 bits (112), Expect = 5e-05
Identities = 62/263 (23%), Positives = 120/263 (45%), Gaps = 40/263 (15%)
Query: 55 LRGLLEMMET---DEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLEN 111
LR LE ME +K+ L + D + + L+E LQS+ + RLA
Sbjct: 284 LRKTLEEMELRIETQKQTLNAR--DESIKKLLEMLQSKGLSAKATEEDHERTRRLA---- 337
Query: 112 DKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLD 171
+ E V + L +Q E + +R+ E HR NA + S +T+ L
Sbjct: 338 EAEMHVHHLESLLEQKEKENSMLRE-----EMHRRFENAPD-----------SAKTKALQ 381
Query: 172 LMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQ-YEKKLKS 230
+ E+ + K+ +++E+ D E++ + +++ L + E + ++++ Y K
Sbjct: 382 TVIEMKDSKI--SSMERGLRDLEEEIQ----MLKSNGALSTEEREEEMKQMEVYRSHSKF 435
Query: 231 TKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKK 290
K+++ LKE+L KE++ + L++K G EI K++L K+ E+ ++
Sbjct: 436 MKNKVEQLKEELSSKEAQWEELKKKAA----GLQAEI----GQVKQELSRKDTELLALQT 487
Query: 291 AVESLMAANEEKDRKIEDLRQCL 313
+E+L + + IE L++ L
Sbjct: 488 KLETLTNQFSDSKQHIEVLKESL 510
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 62.0 bits (149), Expect = 3e-09
Identities = 65/232 (28%), Positives = 110/232 (47%), Gaps = 22/232 (9%)
Query: 100 DVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATE---EMLQ 156
D + RL E Q+ + ++ Q +I DL+ L+ KVN + E LQ
Sbjct: 497 DALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQ 556
Query: 157 QELLSR----TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGL-IQEINDLR 211
++L + +SL+ + L A+ +N LT +E+ +K R E L Q D R
Sbjct: 557 EQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEE---ALAEKERTIERLKEQRDRDER 613
Query: 212 LKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRD 271
K E+D+ Y+K LK K++++ L+ L EKE+ + L+E + G++ R
Sbjct: 614 EKQEEIDN----YKKDLKDLKEKVSLLQGDLSEKEASLLDLKEH-ASSLASSGLKKDSRL 668
Query: 272 ENFKKKLKEKNIEVQKM----KKAVESLM--AANEEKDRKIEDLRQCLNRYK 317
+ + L++K E KM KKA E+ + A+ E +I+ L + + RYK
Sbjct: 669 KTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK 720
Score = 55.5 bits (132), Expect = 3e-07
Identities = 60/234 (25%), Positives = 105/234 (44%), Gaps = 27/234 (11%)
Query: 104 ERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEF-----------CLEEHREK---VN 149
E L +EN+K +++ L QV+ Q +K+ +L+ LEE R + +N
Sbjct: 735 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLN 794
Query: 150 ATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEIND 209
+ + LQ L + +++ + E +++TA + L E+ R +++ +
Sbjct: 795 DSSQQLQDSLRKKDD----RIEELEEALRESVQITAEREMVLAQEESARTNAE--KQVEE 848
Query: 210 LRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEV-KRLQEKLVCKMKGEGVEIV 268
L + + ++ E + KL ST+ LA + L +E K L+E L K + I
Sbjct: 849 LLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAIS 908
Query: 269 DRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLR-QCLNRYKKMQD 321
++D N L E + KK E + A EKDR ++ L+ Q NR K M D
Sbjct: 909 EKDANIA--LLELS---SSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMAD 957
Score = 52.0 bits (123), Expect = 3e-06
Identities = 61/297 (20%), Positives = 129/297 (43%), Gaps = 45/297 (15%)
Query: 53 EDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPG--------NGDVYQE 104
E ++ LLEM+++ +GL + + E +++M HL N + +E
Sbjct: 307 ESIKKLLEMLQS---KGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREE 363
Query: 105 RLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVN--------ATEEMLQ 156
R EN +S + L +E + KI +E L + E++ +TEE +
Sbjct: 364 MHRRFENAPDSA--KTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEER-E 420
Query: 157 QELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSE 216
+E+ + + +I +K +L+ + + L + K E L + +D + +
Sbjct: 421 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKL---ETLTNQFSDSKQHIEV 477
Query: 217 MDSERLQYEKKLKSTKDELASLKEQLEEKES----EVKRLQE---------------KLV 257
+ E++ + E+ +L+ +LEEKE+ + K++Q+ K +
Sbjct: 478 LKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM 537
Query: 258 CKMKGEGVEIVDRD-ENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCL 313
+K V ++ + EN +++L++K ++ +K+ V+SL A D + L + L
Sbjct: 538 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEAL 594
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 62.0 bits (149), Expect = 3e-09
Identities = 56/203 (27%), Positives = 95/203 (46%), Gaps = 18/203 (8%)
Query: 128 EAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVE 187
+AQ E R LE E EK + +++ + E L+ ++ Q +++NLK +
Sbjct: 721 KAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQN----KKVANLKHNQQLEK 776
Query: 188 KDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKES 247
K ++ R E + + N L++ E+ + + ++L +TK LAS ++ L EKE+
Sbjct: 777 KKNAQLLEEVRRREDSMAD-NSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEA 835
Query: 248 EV--------KRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAAN 299
+ K+L+E L K + I ++D N + + K KK E +MA
Sbjct: 836 HLANLRIERRKQLEEILEMKQEALLAAISEKDAN----IALLELSASKKKKTQEEVMALK 891
Query: 300 EEKDRKIEDLR-QCLNRYKKMQD 321
EKDR + L+ Q NR K M D
Sbjct: 892 REKDRLVHQLKQQTQNRMKLMAD 914
Score = 55.8 bits (133), Expect = 2e-07
Identities = 68/300 (22%), Positives = 129/300 (43%), Gaps = 34/300 (11%)
Query: 40 SPFMGSLRALHLVEDLRG--LLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHL-- 95
SP + R L E R L E M +E Q+ T + L + L++Q HL
Sbjct: 187 SPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQL---TIQALQDELRTQRDLNHLLQ 243
Query: 96 --PGNG-------DVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHRE 146
GN ++ +E RL+ + + ++ +L +E +I + L E
Sbjct: 244 QESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDE 303
Query: 147 KVNATEEMLQQELLSRTSLE--TQKLDLMAE----ISNLKLKLTAVEKDRLDYEDKFRDT 200
+ EMLQ + L SLE ++ MAE +S+L++ L EK+ + ++
Sbjct: 304 SIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRR 363
Query: 201 EGLIQE---INDLRLKVSEMDSERLQYEKKLKSTKDELASLKE----QLEEKESEVKRLQ 253
L E L+ + D++ E+ ++ +DE+ LK E++E E+K+++
Sbjct: 364 SQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIE 423
Query: 254 EKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCL 313
K + + + K++L +K E+ ++ +E+L N + + IE L++ L
Sbjct: 424 -----VYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESL 478
Score = 54.7 bits (130), Expect = 4e-07
Identities = 58/273 (21%), Positives = 119/273 (43%), Gaps = 48/273 (17%)
Query: 100 DVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATE---EMLQ 156
D + RL E+ Q+ LT++ +IRD++ LE K+N + E LQ
Sbjct: 493 DALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQ 552
Query: 157 QELLSR----TSLETQKLDLMAEISNLKLKLTAV-----EKDRL----------DYEDKF 197
++L + T+L+ + L + SN L + EK+R+ D ++
Sbjct: 553 EQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERL 612
Query: 198 RDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQ---- 253
+ E +E DL+ KV+ + +E + E L K+ +SL +++S++K L+
Sbjct: 613 EEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIE 672
Query: 254 ------EKLVCKMK---------------GEGVEIVDRDEN-FKKKLKEKNIEVQKMKKA 291
KL ++K + ++ +D++ + ++ + + EV ++ +
Sbjct: 673 QKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEI 732
Query: 292 VESLMAANEEKDRKIEDLRQCLNRYKKMQDTVV 324
++ + +KD+KI +L R+ K Q+ V
Sbjct: 733 LKEVENEKNDKDKKIAELESLTLRHMKDQNKKV 765
Score = 53.9 bits (128), Expect = 7e-07
Identities = 68/289 (23%), Positives = 128/289 (44%), Gaps = 42/289 (14%)
Query: 55 LRGLLEMMET---DEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLEN 111
LR LE ME +K+ L + D + + L+E LQS+ LP R
Sbjct: 280 LRKTLEEMELRIETQKQTLNAR--DESIKKLLEMLQSK----GLPSKSLEDDNERTRRMA 333
Query: 112 DKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLD 171
+ ES V + V+ DQ E +E ++ EE+ ++ L +T+ L
Sbjct: 334 EAESQVSHLEVILDQKE----------------KENIHLREELHRRSQLQPEPAKTKALQ 377
Query: 172 LMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQ-YEKKLKS 230
+ E+ + K+ ++E++ D ED+ + +++ L + E + ++++ Y+ K
Sbjct: 378 TVIEMKDTKI--ASLERNIRDLEDEIQ----MLKANGVLNTEDREEEIKQIEVYKSHSKF 431
Query: 231 TKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKK 290
K ++ LK++L +KESE+ LQ KL + + + E K+ L K ++
Sbjct: 432 MKTKIDQLKQELSKKESELLALQTKLE-TLSNQNSDCKQHIEVLKESLTAKEQRAAILQT 490
Query: 291 AVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEEL 339
V++L EEK+ + + K++QD L + K GE ++
Sbjct: 491 EVDALRLRLEEKESFLN------KKTKQLQD---LTEEKGTLAGEIRDM 530
Score = 51.2 bits (121), Expect = 5e-06
Identities = 64/255 (25%), Positives = 116/255 (45%), Gaps = 42/255 (16%)
Query: 105 RLARLENDKESLVLQVSVLTDQ----VEAQGEKIRDLEFCLEEHREKVNATEEMLQQELL 160
++A LE + L ++ +L E + E+I+ +E + H + + + L+QEL
Sbjct: 386 KIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEV-YKSHSKFMKTKIDQLKQELS 444
Query: 161 SR--------TSLET---QKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQ-EIN 208
+ T LET Q D I LK LTA E+ ++Q E++
Sbjct: 445 KKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQ-----------RAAILQTEVD 493
Query: 209 DLRLKVSEMDSERLQYEKKLKSTKDELASL-------KEQLEEKESEVKRLQEKLVCKMK 261
LRL++ E +S + K+L+ +E +L K+ LE KE ++ LQ+K+ +
Sbjct: 494 ALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQE 553
Query: 262 GEGVEIVDRDE---NFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKK 318
++ D+D+ N K ++K + A+ +L A EK+R IE L++ R +
Sbjct: 554 ----QLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDR 609
Query: 319 MQDTVVLAQGKKGKD 333
+ + + K+ KD
Sbjct: 610 ERLEEIESFRKENKD 624
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 61.2 bits (147), Expect = 5e-09
Identities = 49/235 (20%), Positives = 121/235 (51%), Gaps = 14/235 (5%)
Query: 108 RLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLET 167
+L+ + + L ++ ++ +++AQ E+ ++ EK+ EE +Q++ E
Sbjct: 259 QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ-------EE 311
Query: 168 QKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLI----QEINDLRLKVSEMDSERLQ 223
+ + +I + K+ E+ + E+K R+ E + ++I + K+ E + + +
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 224 YEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNI 283
E+K++ +++ +E++ +E +++ +EK KM + ++ ++DE +++ +E
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 284 EVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEE 338
+ +K+++ +E +M EEK R++E+ Q +KMQ+ Q ++ K E EE
Sbjct: 432 QEEKIRE-LEEMMQDQEEKLREVEEKMQ--EEEEKMQEQEEKIQRQEEKIQEQEE 483
Score = 59.7 bits (143), Expect = 1e-08
Identities = 65/281 (23%), Positives = 132/281 (46%), Gaps = 30/281 (10%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEML--QQELL 160
+E++ R E ++ D++ Q EKIR+ E + E EK+ EE + Q E +
Sbjct: 324 EEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
Query: 161 SRTSLE--TQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMD 218
E Q+ + + + K+ EK + ++K R+ E +E+ K+ E++
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE---EEMWRQEEKIRELE 440
Query: 219 SERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKL---------VCKMKGEGVEIVD 269
E+KL+ ++++ +E+++E+E +++R +EK+ K+ + +I +
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE 500
Query: 270 RDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQ-- 327
++E ++ +EK E ++ + E M EEK R+ E + + +KMQ+ V Q
Sbjct: 501 QEEKMWRQ-EEKMWEQEEKMQEQEEKMQRQEEKMREQE--VRLWQQEEKMQEQEVRLQEL 557
Query: 328 -GKKGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVM 367
+ GK G+ ELL + S ++ P+ TP++
Sbjct: 558 EERLGKLGQKAELLGGAGRE--------SGSQRLPTLTPIL 590
Score = 55.1 bits (131), Expect = 3e-07
Identities = 49/247 (19%), Positives = 118/247 (47%), Gaps = 19/247 (7%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR 162
+E+ +++ +E + Q + +Q E + EK+ E + E EK+ EE + ++
Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436
Query: 163 TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEIND---LRLKVSEMDS 219
LE D ++ ++ K+ E+ + E+K + E IQE + + K+ + +
Sbjct: 437 RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496
Query: 220 ERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLK 279
+ + E+K+ ++++ +E+++E+E +++R +E KM+ + V + ++E K++
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE----KMREQEVRLWQQEE----KMQ 548
Query: 280 EKNIEVQKMKKAVESL--------MAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKG 331
E+ + +Q++++ + L A E +++ L L K Q+ L Q +
Sbjct: 549 EQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDH 608
Query: 332 KDGEYEE 338
G ++
Sbjct: 609 YRGHLQQ 615
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 61.2 bits (147), Expect = 5e-09
Identities = 49/235 (20%), Positives = 121/235 (51%), Gaps = 14/235 (5%)
Query: 108 RLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLET 167
+L+ + + L ++ ++ +++AQ E+ ++ EK+ EE +Q++ E
Sbjct: 259 QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ-------EE 311
Query: 168 QKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLI----QEINDLRLKVSEMDSERLQ 223
+ + +I + K+ E+ + E+K R+ E + ++I + K+ E + + +
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 224 YEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNI 283
E+K++ +++ +E++ +E +++ +EK KM + ++ ++DE +++ +E
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 284 EVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEE 338
+ +K+++ +E +M EEK R++E+ Q +KMQ+ Q ++ K E EE
Sbjct: 432 QEEKIRE-LEEMMQDQEEKLREVEEKMQ--EEEEKMQEQEEKIQRQEEKIQEQEE 483
Score = 59.7 bits (143), Expect = 1e-08
Identities = 65/281 (23%), Positives = 132/281 (46%), Gaps = 30/281 (10%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEML--QQELL 160
+E++ R E ++ D++ Q EKIR+ E + E EK+ EE + Q E +
Sbjct: 324 EEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
Query: 161 SRTSLE--TQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMD 218
E Q+ + + + K+ EK + ++K R+ E +E+ K+ E++
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE---EEMWRQEEKIRELE 440
Query: 219 SERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKL---------VCKMKGEGVEIVD 269
E+KL+ ++++ +E+++E+E +++R +EK+ K+ + +I +
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE 500
Query: 270 RDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQ-- 327
++E ++ +EK E ++ + E M EEK R+ E + + +KMQ+ V Q
Sbjct: 501 QEEKMWRQ-EEKMWEQEEKMQEQEEKMQRQEEKMREQE--VRLWQQEEKMQEQEVRLQEL 557
Query: 328 -GKKGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVM 367
+ GK G+ ELL + S ++ P+ TP++
Sbjct: 558 EERLGKLGQKAELLGGAGRE--------SGSQRLPTLTPIL 590
Score = 55.1 bits (131), Expect = 3e-07
Identities = 49/247 (19%), Positives = 118/247 (47%), Gaps = 19/247 (7%)
Query: 103 QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSR 162
+E+ +++ +E + Q + +Q E + EK+ E + E EK+ EE + ++
Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436
Query: 163 TSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEIND---LRLKVSEMDS 219
LE D ++ ++ K+ E+ + E+K + E IQE + + K+ + +
Sbjct: 437 RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496
Query: 220 ERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLK 279
+ + E+K+ ++++ +E+++E+E +++R +E KM+ + V + ++E K++
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE----KMREQEVRLWQQEE----KMQ 548
Query: 280 EKNIEVQKMKKAVESL--------MAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKG 331
E+ + +Q++++ + L A E +++ L L K Q+ L Q +
Sbjct: 549 EQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDH 608
Query: 332 KDGEYEE 338
G ++
Sbjct: 609 YRGHLQQ 615
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,802,352
Number of Sequences: 37866
Number of extensions: 1889954
Number of successful extensions: 14167
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 277
Number of HSP's successfully gapped in prelim test: 1056
Number of HSP's that attempted gapping in prelim test: 7895
Number of HSP's gapped (non-prelim): 4463
length of query: 1005
length of database: 18,247,518
effective HSP length: 112
effective length of query: 893
effective length of database: 14,006,526
effective search space: 12507827718
effective search space used: 12507827718
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.