Search of human proteins with 28559065

Search of human proteins with 28559065

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28559065 DNA cytosine-5 methyltransferase 3 beta isoform 6
[Homo sapiens]
         (845 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28559065 DNA cytosine-5 methyltransferase 3 beta isoform 6 [H...  1751   0.0  
gi|28559061 DNA cytosine-5 methyltransferase 3 beta isoform 2 [H...  1726   0.0  
gi|5901940 DNA cytosine-5 methyltransferase 3 beta isoform 1 [Ho...  1714   0.0  
gi|28559063 DNA cytosine-5 methyltransferase 3 beta isoform 3 [H...  1504   0.0  
gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Ho...   830   0.0  
gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Ho...   830   0.0  
gi|77176455 DNA cytosine methyltransferase 3 alpha isoform b [Ho...   830   0.0  
gi|28872780 cytosine-5-methyltransferase 3-like protein isoform ...   251   2e-66
gi|28872778 cytosine-5-methyltransferase 3-like protein isoform ...   251   2e-66
gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]         62   2e-09
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    57   7e-08
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    57   9e-08
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]        54   6e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         48   4e-05
gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    42   0.002
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    42   0.002
gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform ...    42   0.002
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    42   0.002
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    42   0.002
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor...    42   0.002
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]                41   0.005
gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]               41   0.005
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    40   0.009
gi|31652259 melanoma ubiquitous mutated protein [Homo sapiens]         39   0.015
gi|4504191 mutS homolog 6 [Homo sapiens]                               39   0.020
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        39   0.026
gi|51173722 bromodomain and PHD finger-containing protein 1 isof...    39   0.026
gi|51173720 bromodomain and PHD finger-containing protein 1 isof...    39   0.026
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    38   0.034
gi|149192855 HLA-B associated transcript 2-like [Homo sapiens]         37   0.059

>gi|28559065 DNA cytosine-5 methyltransferase 3 beta isoform 6 [Homo
           sapiens]
          Length = 845

 Score = 1751 bits (4534), Expect = 0.0
 Identities = 845/845 (100%), Positives = 845/845 (100%)

Query: 1   MEPSPEPPSLESMKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRG 60
           MEPSPEPPSLESMKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRG
Sbjct: 1   MEPSPEPPSLESMKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRG 60

Query: 61  RRSSSRLSKREVSSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNN 120
           RRSSSRLSKREVSSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNN
Sbjct: 61  RRSSSRLSKREVSSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNN 120

Query: 121 NSVSSRERHRPSPRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTI 180
           NSVSSRERHRPSPRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTI
Sbjct: 121 NSVSSRERHRPSPRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTI 180

Query: 181 DLTDDTEDTHGTPQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDL 240
           DLTDDTEDTHGTPQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDL
Sbjct: 181 DLTDDTEDTHGTPQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDL 240

Query: 241 VWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFN 300
           VWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFN
Sbjct: 241 VWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFN 300

Query: 301 LATFNKLVSYRKAMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGL 360
           LATFNKLVSYRKAMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGL
Sbjct: 301 LATFNKLVSYRKAMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGL 360

Query: 361 KPNNTQPENKTRRRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQMASDVANNK 420
           KPNNTQPENKTRRRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQMASDVANNK
Sbjct: 361 KPNNTQPENKTRRRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQMASDVANNK 420

Query: 421 SSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELL 480
           SSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELL
Sbjct: 421 SSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELL 480

Query: 481 LCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQA 540
           LCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQA
Sbjct: 481 LCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQA 540

Query: 541 FFTSDTGLEYEAPKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCE 600
           FFTSDTGLEYEAPKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCE
Sbjct: 541 FFTSDTGLEYEAPKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCE 600

Query: 601 ESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGT 660
           ESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGT
Sbjct: 601 ESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGT 660

Query: 661 GRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSA 720
           GRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSA
Sbjct: 661 GRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSA 720

Query: 721 AHRARYFWGNLPGMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQL 780
           AHRARYFWGNLPGMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQL
Sbjct: 721 AHRARYFWGNLPGMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQL 780

Query: 781 FPVVMNGKEDVLWCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKD 840
           FPVVMNGKEDVLWCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKD
Sbjct: 781 FPVVMNGKEDVLWCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKD 840

Query: 841 YFACE 845
           YFACE
Sbjct: 841 YFACE 845


>gi|28559061 DNA cytosine-5 methyltransferase 3 beta isoform 2 [Homo
           sapiens]
          Length = 833

 Score = 1726 bits (4470), Expect = 0.0
 Identities = 833/833 (100%), Positives = 833/833 (100%)

Query: 13  MKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREV 72
           MKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREV
Sbjct: 1   MKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREV 60

Query: 73  SSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPS 132
           SSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPS
Sbjct: 61  SSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPS 120

Query: 133 PRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGT 192
           PRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGT
Sbjct: 121 PRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGT 180

Query: 193 PQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWP 252
           PQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWP
Sbjct: 181 PQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWP 240

Query: 253 AMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRK 312
           AMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRK
Sbjct: 241 AMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRK 300

Query: 313 AMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPENKTR 372
           AMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPENKTR
Sbjct: 301 AMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPENKTR 360

Query: 373 RRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQMASDVANNKSSLEDGCLSCGR 432
           RRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQMASDVANNKSSLEDGCLSCGR
Sbjct: 361 RRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQMASDVANNKSSLEDGCLSCGR 420

Query: 433 KNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFC 492
           KNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFC
Sbjct: 421 KNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFC 480

Query: 493 VECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEA 552
           VECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEA
Sbjct: 481 VECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEA 540

Query: 553 PKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEG 612
           PKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEG
Sbjct: 541 PKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEG 600

Query: 613 NIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLN 672
           NIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLN
Sbjct: 601 NIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLN 660

Query: 673 YSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLP 732
           YSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLP
Sbjct: 661 YSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLP 720

Query: 733 GMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQLFPVVMNGKEDVL 792
           GMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQLFPVVMNGKEDVL
Sbjct: 721 GMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQLFPVVMNGKEDVL 780

Query: 793 WCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFACE 845
           WCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFACE
Sbjct: 781 WCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFACE 833


>gi|5901940 DNA cytosine-5 methyltransferase 3 beta isoform 1 [Homo
           sapiens]
          Length = 853

 Score = 1714 bits (4439), Expect = 0.0
 Identities = 833/853 (97%), Positives = 833/853 (97%), Gaps = 20/853 (2%)

Query: 13  MKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREV 72
           MKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREV
Sbjct: 1   MKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREV 60

Query: 73  SSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPS 132
           SSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPS
Sbjct: 61  SSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPS 120

Query: 133 PRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGT 192
           PRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGT
Sbjct: 121 PRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGT 180

Query: 193 PQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWP 252
           PQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWP
Sbjct: 181 PQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWP 240

Query: 253 AMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRK 312
           AMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRK
Sbjct: 241 AMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRK 300

Query: 313 AMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQP----- 367
           AMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQP     
Sbjct: 301 AMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPVVNKS 360

Query: 368 ---------------ENKTRRRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQM 412
                          ENKTRRRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQM
Sbjct: 361 KVRRAGSRKLESRKYENKTRRRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQM 420

Query: 413 ASDVANNKSSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTV 472
           ASDVANNKSSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTV
Sbjct: 421 ASDVANNKSSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTV 480

Query: 473 CCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRK 532
           CCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRK
Sbjct: 481 CCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRK 540

Query: 533 DWNVRLQAFFTSDTGLEYEAPKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGK 592
           DWNVRLQAFFTSDTGLEYEAPKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGK
Sbjct: 541 DWNVRLQAFFTSDTGLEYEAPKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGK 600

Query: 593 YVASEVCEESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPA 652
           YVASEVCEESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPA
Sbjct: 601 YVASEVCEESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPA 660

Query: 653 RKGLYEGTGRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVM 712
           RKGLYEGTGRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVM
Sbjct: 661 RKGLYEGTGRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVM 720

Query: 713 IDAIKVSAAHRARYFWGNLPGMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNS 772
           IDAIKVSAAHRARYFWGNLPGMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNS
Sbjct: 721 IDAIKVSAAHRARYFWGNLPGMNRPVIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNS 780

Query: 773 IKQGKNQLFPVVMNGKEDVLWCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIR 832
           IKQGKNQLFPVVMNGKEDVLWCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIR
Sbjct: 781 IKQGKNQLFPVVMNGKEDVLWCTELERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIR 840

Query: 833 HLFAPLKDYFACE 845
           HLFAPLKDYFACE
Sbjct: 841 HLFAPLKDYFACE 853


>gi|28559063 DNA cytosine-5 methyltransferase 3 beta isoform 3 [Homo
           sapiens]
          Length = 770

 Score = 1504 bits (3894), Expect = 0.0
 Identities = 724/724 (100%), Positives = 724/724 (100%)

Query: 13  MKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREV 72
           MKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREV
Sbjct: 1   MKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREV 60

Query: 73  SSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPS 132
           SSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPS
Sbjct: 61  SSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPS 120

Query: 133 PRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGT 192
           PRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGT
Sbjct: 121 PRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGT 180

Query: 193 PQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWP 252
           PQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWP
Sbjct: 181 PQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWP 240

Query: 253 AMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRK 312
           AMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRK
Sbjct: 241 AMVVSWKATSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRK 300

Query: 313 AMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPENKTR 372
           AMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPENKTR
Sbjct: 301 AMYHALEKARVRAGKTFPSSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPENKTR 360

Query: 373 RRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQMASDVANNKSSLEDGCLSCGR 432
           RRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQMASDVANNKSSLEDGCLSCGR
Sbjct: 361 RRTADDSATSDYCPAPKRLKTNCYNNGKDRGDEDQSREQMASDVANNKSSLEDGCLSCGR 420

Query: 433 KNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFC 492
           KNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFC
Sbjct: 421 KNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFC 480

Query: 493 VECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEA 552
           VECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEA
Sbjct: 481 VECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEA 540

Query: 553 PKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEG 612
           PKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEG
Sbjct: 541 PKLYPAIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEG 600

Query: 613 NIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLN 672
           NIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLN
Sbjct: 601 NIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLN 660

Query: 673 YSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLP 732
           YSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLP
Sbjct: 661 YSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLP 720

Query: 733 GMNR 736
           GMNR
Sbjct: 721 GMNR 724


>gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score =  830 bits (2145), Expect = 0.0
 Identities = 396/647 (61%), Positives = 488/647 (75%), Gaps = 14/647 (2%)

Query: 211 GMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGM 270
           G ++    A     D  EY+DG+ FGIG+LVWGK++GFSWWP  +VSW  T + +A  G 
Sbjct: 266 GSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGT 325

Query: 271 RWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFP 330
           RWV WFGDGKFS V  +KL+ L  F   F+ AT+NK   YRKA+Y  L+ A  RAGK FP
Sbjct: 326 RWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFP 385

Query: 331 -------SSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPENKTRRRTAD---DSA 380
                  S    ++E Q KPM+EWA GGF+P+G +GL+P   + +N  +    D   +  
Sbjct: 386 VCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEE-KNPYKEVYTDMWVEPE 444

Query: 381 TSDYCPAPKRLKTNCYNNGKDRGDE---DQSREQMASDVANNKSSLEDGCLSCGRKNPVS 437
            + Y P P   K       K +  E   +++RE++  +V     ++ED C+SCG  N   
Sbjct: 445 AAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTL 504

Query: 438 FHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLE 497
            HPLF GG+CQ C++ FLE  Y YDDDGYQSYCT+CC GRE+L+C N +CCRCFCVEC++
Sbjct: 505 EHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVD 564

Query: 498 VLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEAPKLYP 557
           +LVG G A  A  ++PW+CYMC  +  +G+LRRR+DW  RLQ FF ++   E++ PK+YP
Sbjct: 565 LLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYP 624

Query: 558 AIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEGNIKYV 617
            +PA +R+PIRVLSLFDGIATG LVLK+LGI+V +Y+ASEVCE+SI VG V+H+G I YV
Sbjct: 625 PVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYV 684

Query: 618 NDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYSRPK 677
            DVR++T+K+I+EWGPFDLVIGGSPCNDLS VNPARKGLYEGTGRLFFEFY LL+ +RPK
Sbjct: 685 GDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPK 744

Query: 678 EGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLPGMNRP 737
           EGDDRPFFW+FENVVAM V DKRDISRFLE NPVMIDA +VSAAHRARYFWGNLPGMNRP
Sbjct: 745 EGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRP 804

Query: 738 VIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQLFPVVMNGKEDVLWCTEL 797
           + ++ NDKLELQ+CLE+ RIAK  KV+TITT+SNSIKQGK+Q FPV MN KED+LWCTE+
Sbjct: 805 LASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEM 864

Query: 798 ERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFAC 844
           ER+FGFPVHYTDVSNM R ARQ+LLGRSWSVPVIRHLFAPLK+YFAC
Sbjct: 865 ERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFAC 911


>gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score =  830 bits (2145), Expect = 0.0
 Identities = 396/647 (61%), Positives = 488/647 (75%), Gaps = 14/647 (2%)

Query: 211 GMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGM 270
           G ++    A     D  EY+DG+ FGIG+LVWGK++GFSWWP  +VSW  T + +A  G 
Sbjct: 266 GSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGT 325

Query: 271 RWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFP 330
           RWV WFGDGKFS V  +KL+ L  F   F+ AT+NK   YRKA+Y  L+ A  RAGK FP
Sbjct: 326 RWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFP 385

Query: 331 -------SSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPENKTRRRTAD---DSA 380
                  S    ++E Q KPM+EWA GGF+P+G +GL+P   + +N  +    D   +  
Sbjct: 386 VCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEE-KNPYKEVYTDMWVEPE 444

Query: 381 TSDYCPAPKRLKTNCYNNGKDRGDE---DQSREQMASDVANNKSSLEDGCLSCGRKNPVS 437
            + Y P P   K       K +  E   +++RE++  +V     ++ED C+SCG  N   
Sbjct: 445 AAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTL 504

Query: 438 FHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLE 497
            HPLF GG+CQ C++ FLE  Y YDDDGYQSYCT+CC GRE+L+C N +CCRCFCVEC++
Sbjct: 505 EHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVD 564

Query: 498 VLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEAPKLYP 557
           +LVG G A  A  ++PW+CYMC  +  +G+LRRR+DW  RLQ FF ++   E++ PK+YP
Sbjct: 565 LLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYP 624

Query: 558 AIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEGNIKYV 617
            +PA +R+PIRVLSLFDGIATG LVLK+LGI+V +Y+ASEVCE+SI VG V+H+G I YV
Sbjct: 625 PVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYV 684

Query: 618 NDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYSRPK 677
            DVR++T+K+I+EWGPFDLVIGGSPCNDLS VNPARKGLYEGTGRLFFEFY LL+ +RPK
Sbjct: 685 GDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPK 744

Query: 678 EGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLPGMNRP 737
           EGDDRPFFW+FENVVAM V DKRDISRFLE NPVMIDA +VSAAHRARYFWGNLPGMNRP
Sbjct: 745 EGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRP 804

Query: 738 VIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQLFPVVMNGKEDVLWCTEL 797
           + ++ NDKLELQ+CLE+ RIAK  KV+TITT+SNSIKQGK+Q FPV MN KED+LWCTE+
Sbjct: 805 LASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEM 864

Query: 798 ERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFAC 844
           ER+FGFPVHYTDVSNM R ARQ+LLGRSWSVPVIRHLFAPLK+YFAC
Sbjct: 865 ERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFAC 911


>gi|77176455 DNA cytosine methyltransferase 3 alpha isoform b [Homo
           sapiens]
          Length = 723

 Score =  830 bits (2145), Expect = 0.0
 Identities = 396/647 (61%), Positives = 488/647 (75%), Gaps = 14/647 (2%)

Query: 211 GMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGM 270
           G ++    A     D  EY+DG+ FGIG+LVWGK++GFSWWP  +VSW  T + +A  G 
Sbjct: 77  GSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGT 136

Query: 271 RWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGKTFP 330
           RWV WFGDGKFS V  +KL+ L  F   F+ AT+NK   YRKA+Y  L+ A  RAGK FP
Sbjct: 137 RWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFP 196

Query: 331 -------SSPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNTQPENKTRRRTAD---DSA 380
                  S    ++E Q KPM+EWA GGF+P+G +GL+P   + +N  +    D   +  
Sbjct: 197 VCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEEE-KNPYKEVYTDMWVEPE 255

Query: 381 TSDYCPAPKRLKTNCYNNGKDRGDE---DQSREQMASDVANNKSSLEDGCLSCGRKNPVS 437
            + Y P P   K       K +  E   +++RE++  +V     ++ED C+SCG  N   
Sbjct: 256 AAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTL 315

Query: 438 FHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLE 497
            HPLF GG+CQ C++ FLE  Y YDDDGYQSYCT+CC GRE+L+C N +CCRCFCVEC++
Sbjct: 316 EHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVD 375

Query: 498 VLVGTGTAAEAKLQEPWSCYMCLPQRCHGVLRRRKDWNVRLQAFFTSDTGLEYEAPKLYP 557
           +LVG G A  A  ++PW+CYMC  +  +G+LRRR+DW  RLQ FF ++   E++ PK+YP
Sbjct: 376 LLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYP 435

Query: 558 AIPAARRRPIRVLSLFDGIATGYLVLKELGIKVGKYVASEVCEESIAVGTVKHEGNIKYV 617
            +PA +R+PIRVLSLFDGIATG LVLK+LGI+V +Y+ASEVCE+SI VG V+H+G I YV
Sbjct: 436 PVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYV 495

Query: 618 NDVRNITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYSRPK 677
            DVR++T+K+I+EWGPFDLVIGGSPCNDLS VNPARKGLYEGTGRLFFEFY LL+ +RPK
Sbjct: 496 GDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPK 555

Query: 678 EGDDRPFFWMFENVVAMKVGDKRDISRFLECNPVMIDAIKVSAAHRARYFWGNLPGMNRP 737
           EGDDRPFFW+FENVVAM V DKRDISRFLE NPVMIDA +VSAAHRARYFWGNLPGMNRP
Sbjct: 556 EGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRP 615

Query: 738 VIASKNDKLELQDCLEYNRIAKLKKVQTITTKSNSIKQGKNQLFPVVMNGKEDVLWCTEL 797
           + ++ NDKLELQ+CLE+ RIAK  KV+TITT+SNSIKQGK+Q FPV MN KED+LWCTE+
Sbjct: 616 LASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEM 675

Query: 798 ERIFGFPVHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFAC 844
           ER+FGFPVHYTDVSNM R ARQ+LLGRSWSVPVIRHLFAPLK+YFAC
Sbjct: 676 ERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFAC 722


>gi|28872780 cytosine-5-methyltransferase 3-like protein isoform 2
           [Homo sapiens]
          Length = 386

 Score =  251 bits (641), Expect = 2e-66
 Identities = 127/327 (38%), Positives = 182/327 (55%), Gaps = 32/327 (9%)

Query: 409 REQMASDVANNKSSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQS 468
           R+ +A +V  N+ ++ED C+ CG     + HPLFEGG+C  C+D+FL+  ++YDDDGYQS
Sbjct: 35  RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94

Query: 469 YCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVL 528
           YC++CC G  LL+C N  C RC+C EC++ LVG GT+ +      W CY+CLP    G+L
Sbjct: 95  YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154

Query: 529 RRRKDWNVRLQAFFTSDTGLEYEAP-KLYPAIPAARRRPIRVLSLFDGIATGYLVLKELG 587
           +RR+ W  +L+AF+      E E P +++  +P  RR+P+RVLSLF+ I      L  LG
Sbjct: 155 QRRRKWRSQLKAFYDR----ESENPLEMFETVPVWRRQPVRVLSLFEDIKK---ELTSLG 207

Query: 588 IKVGKYVASEVCEESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLS 647
                            + +    G +K+V DV +  +K++EEWGPFDLV G +P     
Sbjct: 208 F----------------LESGSDPGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP----- 246

Query: 648 NVNPARKGLYEGTGRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLE 707
              P             F+F+ LL Y+RPK G  RPFFWMF + + +   D    SRFLE
Sbjct: 247 ---PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLE 303

Query: 708 CNPVMIDAIKVSAAHRARYFWGNLPGM 734
             PV I  +   +   A   W N+P +
Sbjct: 304 MEPVTIPDVHGGSLQNAVRVWSNIPAI 330


>gi|28872778 cytosine-5-methyltransferase 3-like protein isoform 1
           [Homo sapiens]
          Length = 387

 Score =  251 bits (641), Expect = 2e-66
 Identities = 127/327 (38%), Positives = 182/327 (55%), Gaps = 32/327 (9%)

Query: 409 REQMASDVANNKSSLEDGCLSCGRKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQS 468
           R+ +A +V  N+ ++ED C+ CG     + HPLFEGG+C  C+D+FL+  ++YDDDGYQS
Sbjct: 35  RDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQS 94

Query: 469 YCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLPQRCHGVL 528
           YC++CC G  LL+C N  C RC+C EC++ LVG GT+ +      W CY+CLP    G+L
Sbjct: 95  YCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLL 154

Query: 529 RRRKDWNVRLQAFFTSDTGLEYEAP-KLYPAIPAARRRPIRVLSLFDGIATGYLVLKELG 587
           +RR+ W  +L+AF+      E E P +++  +P  RR+P+RVLSLF+ I      L  LG
Sbjct: 155 QRRRKWRSQLKAFYDR----ESENPLEMFETVPVWRRQPVRVLSLFEDIKK---ELTSLG 207

Query: 588 IKVGKYVASEVCEESIAVGTVKHEGNIKYVNDVRNITKKNIEEWGPFDLVIGGSPCNDLS 647
                            + +    G +K+V DV +  +K++EEWGPFDLV G +P     
Sbjct: 208 F----------------LESGSDPGQLKHVVDVTDTVRKDVEEWGPFDLVYGATP----- 246

Query: 648 NVNPARKGLYEGTGRLFFEFYHLLNYSRPKEGDDRPFFWMFENVVAMKVGDKRDISRFLE 707
              P             F+F+ LL Y+RPK G  RPFFWMF + + +   D    SRFLE
Sbjct: 247 ---PLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASRFLE 303

Query: 708 CNPVMIDAIKVSAAHRARYFWGNLPGM 734
             PV I  +   +   A   W N+P +
Sbjct: 304 MEPVTIPDVHGGSLQNAVRVWSNIPAI 330


>gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]
          Length = 590

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 73/260 (28%), Positives = 100/260 (38%), Gaps = 48/260 (18%)

Query: 78  YTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERH--RPSPRS 135
           Y  +L G+ +G   D S  P            ++ PA    + +S SS E    +  P+ 
Sbjct: 349 YRAELVGELNGYLRDSSPAPC-----------ADGPAGGLADLSSGSSGEDDDFKSCPQG 397

Query: 136 TRGRQG--------RNHVDESPVEFPATRSL-RRRATASAGTPWPSPPSSYLTIDLTDDT 186
            +GR+G            D +     ++ SL   R++ S GTP             T D 
Sbjct: 398 PQGREGLAFLVSCPEGRADCASESACSSDSLDEARSSGSEGTPAD-----------TGDL 446

Query: 187 EDTHGTPQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIK 246
              HG    S +  AR         + +  V            +DG+   +GD+VWGKI 
Sbjct: 447 SPGHGASAPSVSREARQTVPPLTVRLHTQSVS-------ECITEDGRTVAVGDIVWGKIH 499

Query: 247 GFSWWPAMVVSWKATSKRQAMSGMR--WVQWFGDGKFSEVSADKLVALGLFSQHFNLATF 304
           GF WWPA V+      K       R   V WFG    S +S  K   L  FS+ F L  F
Sbjct: 500 GFPWWPARVLDISLGQKEDGEPSWREAKVSWFGSPTTSFLSISK---LSPFSEFFKL-RF 555

Query: 305 N--KLVSYRKAMYHALEKAR 322
           N  K   YRKA+  A   AR
Sbjct: 556 NRKKKGMYRKAITEAANAAR 575


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 19/134 (14%)

Query: 404 DEDQSREQMASDVANNKSSLEDG------CLSCGR------KNPVSFHPLFEGGLCQTCR 451
           +ED S E   +D+       EDG      C +CG+      K+ +  HP  +  +C+ C 
Sbjct: 104 NEDASNENSENDITMQSLPKEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCF 163

Query: 452 DRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQ 511
             ++      D DG    C  C EG  L+ C    C   FC +C  +L   G    + + 
Sbjct: 164 KYYMSDDISRDSDGMDEQCRWCAEGGNLICCD--FCHNAFCKKC--ILRNLGRKELSTIM 219

Query: 512 E---PWSCYMCLPQ 522
           +    W CY+C P+
Sbjct: 220 DENNQWYCYICHPE 233


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 23/143 (16%)

Query: 397 NNGKD--RGDEDQSREQMASDVANNKSSLEDG------CLSCGR------KNPVSFHPLF 442
           N  KD  +G E +SR +M ++  N K   EDG      C +CG+      K+ +  HP  
Sbjct: 135 NEDKDDFKGPEFRSRSKMKTE--NLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSL 192

Query: 443 EGGLCQTCRDRFLELFYMYDDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGT 502
           +  +C+ C   ++      D DG    C  C EG  L+ C    C   FC +C  +L   
Sbjct: 193 QVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCD--FCHNAFCKKC--ILRNL 248

Query: 503 GTAAEAKLQE---PWSCYMCLPQ 522
           G    + + +    W CY+C P+
Sbjct: 249 GRKELSTIMDENNQWYCYICHPE 271


>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
          Length = 755

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 46/174 (26%), Positives = 73/174 (41%), Gaps = 33/174 (18%)

Query: 172 SPPSSYLTIDLTDDTEDTHGTPQSSSTPYARLAQDSQQGGMESPQVEADSGDGDSSEY-- 229
           S  +S  +ID TDD + ++    SS +       D   G M +P   + S      +   
Sbjct: 577 SSSASVCSIDSTDDLKSSNSECSSSES------FDFPPGSMHAPSTSSTSSSSKEEKKLS 630

Query: 230 -----------------QDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR- 271
                             DG+   +GD+VW KI GF WWPA +++   + K   +   + 
Sbjct: 631 NSLKMKVFSKNVSKCVTPDGRTICVGDIVWAKIYGFPWWPARILTITVSRKDNGLLVRQE 690

Query: 272 -WVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVS--YRKAMYHALEKAR 322
             + WFG    S ++   L  L  F ++F  + FNK     YRKA+  A + A+
Sbjct: 691 ARISWFGSPTTSFLA---LSQLSPFLENFQ-SRFNKKRKGLYRKAITEAAKAAK 740


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 52/189 (27%), Positives = 79/189 (41%), Gaps = 35/189 (18%)

Query: 56  PEIRGRRSSSRLSKREVSSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAV 115
           P  R RRS S + +R  SS       L+G         S +P  PK   +   R+ SP  
Sbjct: 334 PPPRHRRSRSPVRRRRRSSA-----SLSGSSSSSSSSRSRSP--PK---KPPKRTSSPPR 383

Query: 116 RTRNNNSVSS--RERHRPSPRSTRGRQGRNHVDESPVEFPATRSLRRRATASAG------ 167
           +TR  +  +S  R RHRPSP +T   + R+    SP    + R+ + R + S G      
Sbjct: 384 KTRRLSPSASPPRRRHRPSPPATPPPKTRH----SPTPQQSNRTRKSRVSVSPGRTSGKV 439

Query: 168 --------TPWPSPPSSYLTIDLTDDTEDTHGTPQSSSTPYARLAQDSQQGGMESPQVEA 219
                      PSP      ++L++  ED  G   ++ +      Q  +Q   ++ Q  +
Sbjct: 440 TKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADS-----VQQRRQYRRQNQQSSS 494

Query: 220 DSGDGDSSE 228
           DSG   SSE
Sbjct: 495 DSGSSSSSE 503



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 7/78 (8%)

Query: 106 TRTRSESPA-VRTRNNNSVSSRE---RHRPSPR---STRGRQGRNHVDESPVEFPATRSL 158
           +RTRS SP+  R R  +   SR    R RPSPR   S R R     +   P    +   +
Sbjct: 286 SRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPV 345

Query: 159 RRRATASAGTPWPSPPSS 176
           RRR  +SA     S  SS
Sbjct: 346 RRRRRSSASLSGSSSSSS 363



 Score = 30.4 bits (67), Expect = 7.2
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 3/60 (5%)

Query: 109 RSESPAVRTRNNNSVSSRERHRPSPRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGT 168
           +  SP+  TR   S    +RH PSPR    R  +      PV   A+ S +RR + S  T
Sbjct: 662 KGSSPSRSTREARSPQPNKRHSPSPRP---RAPQTSSSPPPVRRGASSSPQRRQSPSPST 718


>gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform 3
           [Homo sapiens]
          Length = 647

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 6/51 (11%)

Query: 234 EFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR------WVQWFGD 278
           ++ +GDLVW K+ G+ WWP MV +         + G +       VQ+FGD
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGD 269


>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 6/51 (11%)

Query: 234 EFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR------WVQWFGD 278
           ++ +GDLVW K+ G+ WWP MV +         + G +       VQ+FGD
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGD 269



 Score = 33.5 bits (75), Expect = 0.85
 Identities = 12/39 (30%), Positives = 21/39 (53%)

Query: 217 VEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMV 255
           +E   G    ++ + GK+    D++W K+  + WWPA V
Sbjct: 860 IEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEV 898



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 5/51 (9%)

Query: 470  CTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPW-SCYMC 519
            C  C +G +L+LC    C + + + CL    G G     K + PW  C +C
Sbjct: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCL----GLGKRPFGKWECPWHHCDVC 1288


>gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform 4
           [Homo sapiens]
          Length = 629

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 6/51 (11%)

Query: 234 EFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR------WVQWFGD 278
           ++ +GDLVW K+ G+ WWP MV +         + G +       VQ+FGD
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGD 269


>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 6/51 (11%)

Query: 234 EFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR------WVQWFGD 278
           ++ +GDLVW K+ G+ WWP MV +         + G +       VQ+FGD
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGD 269



 Score = 33.5 bits (75), Expect = 0.85
 Identities = 12/39 (30%), Positives = 21/39 (53%)

Query: 217 VEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMV 255
           +E   G    ++ + GK+    D++W K+  + WWPA V
Sbjct: 860 IEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEV 898



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 5/51 (9%)

Query: 470  CTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPW-SCYMC 519
            C  C +G +L+LC    C + + + CL    G G     K + PW  C +C
Sbjct: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCL----GLGKRPFGKWECPWHHCDVC 1288


>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 6/51 (11%)

Query: 234 EFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR------WVQWFGD 278
           ++ +GDLVW K+ G+ WWP MV +         + G +       VQ+FGD
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGD 269



 Score = 33.5 bits (75), Expect = 0.85
 Identities = 12/39 (30%), Positives = 21/39 (53%)

Query: 217 VEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMV 255
           +E   G    ++ + GK+    D++W K+  + WWPA V
Sbjct: 860 IEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEV 898



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 5/51 (9%)

Query: 470  CTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPW-SCYMC 519
            C  C +G +L+LC    C + + + CL    G G     K + PW  C +C
Sbjct: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCL----GLGKRPFGKWECPWHHCDVC 1288


>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 6/51 (11%)

Query: 234 EFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMR------WVQWFGD 278
           ++ +GDLVW K+ G+ WWP MV +         + G +       VQ+FGD
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGD 269



 Score = 33.5 bits (75), Expect = 0.85
 Identities = 12/39 (30%), Positives = 21/39 (53%)

Query: 217 VEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMV 255
           +E   G    ++ + GK+    D++W K+  + WWPA V
Sbjct: 860 IEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEV 898



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 5/51 (9%)

Query: 470  CTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPW-SCYMC 519
            C  C +G +L+LC    C + + + CL    G G     K + PW  C +C
Sbjct: 1242 CFRCGDGGQLVLCDRKFCTKAYHLSCL----GLGKRPFGKWECPWHHCDVC 1288


>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
          Length = 1437

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 15/32 (46%), Positives = 21/32 (65%)

Query: 226 SSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVS 257
           ++E   G +F +GDLVW K+  + WWP MV S
Sbjct: 259 TTEVSTGVKFQVGDLVWSKVGTYPWWPCMVSS 290



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 12/43 (27%), Positives = 22/43 (51%)

Query: 213 ESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMV 255
           E   +E   G  + ++ + GK+     +VW K+  + WWPA +
Sbjct: 936 ECLSIEMPEGCWNCNDCKAGKKLHYKQIVWVKLGNYRWWPAEI 978



 Score = 30.8 bits (68), Expect = 5.5
 Identities = 10/33 (30%), Positives = 19/33 (57%)

Query: 466  YQSYCTVCCEGRELLLCSNTSCCRCFCVECLEV 498
            ++ YC  C +G EL++C    C + + + CL +
Sbjct: 1320 HEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNL 1352


>gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]
          Length = 645

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 15/32 (46%), Positives = 21/32 (65%)

Query: 226 SSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVS 257
           ++E   G +F +GDLVW K+  + WWP MV S
Sbjct: 259 TTEVSTGVKFQVGDLVWSKVGTYPWWPCMVSS 290


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 43/168 (25%), Positives = 66/168 (39%), Gaps = 23/168 (13%)

Query: 358 EGLKPNNTQPENKTRRRTADDSATSDYCPAPKRLKTNCYNNGKDRG---DEDQSREQMAS 414
           EG  PN  + + K   R  D         AP ++K   + + + R    D+D   E    
Sbjct: 264 EGKGPN-ARRKPKGSPRVPDAKKPKPKKVAPLKIKLGGFGSKRKRSSSEDDDLDVESDFD 322

Query: 415 DVANNKSSLEDGCLSCG---RKNPVSFHPLFEGGLCQTCRDRFLELFYMYDDDGYQSYCT 471
           D + N  S+ DG  S     RK   +     +G    T  D +        +  +Q YC 
Sbjct: 323 DASINSYSVSDGSTSRSSRSRKKLRTTKKKKKGEEEVTAVDGY--------ETDHQDYCE 374

Query: 472 VCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMC 519
           VC +G E++LC   +C R + + CL+         E   +  WSC  C
Sbjct: 375 VCQQGGEIILCD--TCPRAYHMVCLD------PDMEKAPEGKWSCPHC 414



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 2/35 (5%)

Query: 462 DDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECL 496
           +DD +  +C VC +G ELL C   +C   + + CL
Sbjct: 444 EDDHHMEFCRVCKDGGELLCCD--TCPSSYHIHCL 476


>gi|31652259 melanoma ubiquitous mutated protein [Homo sapiens]
          Length = 711

 Score = 39.3 bits (90), Expect = 0.015
 Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 18/127 (14%)

Query: 148 SPVEFPATR-SLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGTPQSSSTPYARLAQD 206
           SP   P  R S+  R+TA  G     PP S+ + D T         P   S    +  Q 
Sbjct: 327 SPGPGPGPRESVTPRSTARLG-----PPPSHASADAT------RCLPCPDSQKLEKECQS 375

Query: 207 SQQG-GMESPQ--VEADSGDGDSSE---YQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKA 260
           S++  G  S +  +E D  D +      Y + + F +G LVW K K + +WPA+V S + 
Sbjct: 376 SEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQ 435

Query: 261 TSKRQAM 267
             K+ ++
Sbjct: 436 RDKKASV 442


>gi|4504191 mutS homolog 6 [Homo sapiens]
          Length = 1360

 Score = 38.9 bits (89), Expect = 0.020
 Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 3/48 (6%)

Query: 234 EFGIGDLVWGKIKGFSWWPAMVVS--WKATSKRQAMSGMR-WVQWFGD 278
           +F  GDLVW K++G+ WWP +V +  +  T  R+    +R  VQ+F D
Sbjct: 89  DFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRVHVQFFDD 136


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 38.5 bits (88), Expect = 0.026
 Identities = 50/207 (24%), Positives = 82/207 (39%), Gaps = 19/207 (9%)

Query: 2   EPSPEPPSLESMKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGR 61
           +P+PEPP   S+  ++           ++      G  S+ SS   P  E  ++ + +  
Sbjct: 162 QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSS---PRRERKKSSKKKKH 218

Query: 62  RSSSRLSKREVSSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRS-----ESPAVR 116
           RS S   KR+  S    ++  + D   +    S TP  PK  R  R+ S      S   R
Sbjct: 219 RSESESKKRKHRSPTPKSKRKSKDKKRKRSR-STTPA-PKSRRAHRSTSADSASSSDTSR 276

Query: 117 TRNNNSVSSRERHRPSPRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTPWPSPPSS 176
           +R+ ++ +       + RS     GR    ++P   P T S +R ++    T  PS P  
Sbjct: 277 SRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYE 336

Query: 177 YLTIDLTDDTEDTHGT-----PQSSST 198
               D   D ++   T     P+ SST
Sbjct: 337 ----DKDKDKKEKSATRPSPSPERSST 359



 Score = 37.7 bits (86), Expect = 0.045
 Identities = 55/234 (23%), Positives = 88/234 (37%), Gaps = 31/234 (13%)

Query: 8    PSLESMKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRL 67
            PSL+  +  TR  +G   +    D++   G  S+QS  S P+L+A+  P    R  SS  
Sbjct: 1367 PSLDMKEQSTRS-SGHSSSELSPDAVEKAGMSSNQSISS-PVLDAV--PRTPSRERSSSA 1422

Query: 68   SKREVSSLLSYTQDLTGDGDGEDG--DGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSS 125
            S  E+   L  T           G  DGS TP    L   +    + P   +R  +   S
Sbjct: 1423 SSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDS 1482

Query: 126  RERHRPSPRSTRGR----------------QGRNHVDESPVE--FPATRSLRRRATASAG 167
                +  P++ R R                Q      ES V+    A   L +R+ + + 
Sbjct: 1483 SPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSS 1542

Query: 168  TPWPSPPSSYLTIDLTDDTEDTHGTPQSSSTPYARLAQDSQQGGMESPQVEADS 221
                  PS+        +  ++  +P S +     L Q S+ G   SP+V++ S
Sbjct: 1543 QELDVKPSA-----SPQERSESDSSPDSKAKTRTPLRQRSRSG--SSPEVDSKS 1589



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 36/147 (24%), Positives = 57/147 (38%), Gaps = 23/147 (15%)

Query: 44   SDSPPILEAIRTPEIRGRRSSSRLSKREVSSLLSYTQDLTGDGDGE-DGDGSDTPVMPKL 102
            +  P  L A++  + R   SSS  S    SS  S +   +  G    D +GS  PV P++
Sbjct: 2515 AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEV 2574

Query: 103  ---------------FRETRTRSESPAVRTRNNNSVSSRERHRPSPRSTRGRQGRNHVDE 147
                            RE R    +PA R R ++S SS      S  S+           
Sbjct: 2575 ALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS-------SS 2627

Query: 148  SPVEFPATRSLRRRATASAGTPWPSPP 174
            S     ++ S    +++S+ +P P+ P
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSPSPAKP 2654



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 53/211 (25%), Positives = 72/211 (34%), Gaps = 49/211 (23%)

Query: 4    SPEPPSLESMKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIR-------TP 56
            S    S  S    +   +   D+ G    +    A     S +P   EA+R       TP
Sbjct: 2541 SSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTP 2600

Query: 57   EIRGRRSSSRLSKREVSSLLSYTQDLTGDGDGEDGDGSDT-------------------- 96
              R RRSSS  S    SS  S +   +          S +                    
Sbjct: 2601 AKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP 2660

Query: 97   -PVMPKLFRETRTRSESP-----AVRTRNNNSVSSRERHRPSPR----------STRG-R 139
             P  PK       RS SP     ++R   + S S  ER RPSP+          S RG R
Sbjct: 2661 KPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSR 2720

Query: 140  QGRNHVDESPV-----EFPATRSLRRRATAS 165
            +G+     SP      E P+ R +R R++ S
Sbjct: 2721 RGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751



 Score = 33.5 bits (75), Expect = 0.85
 Identities = 36/116 (31%), Positives = 48/116 (41%), Gaps = 4/116 (3%)

Query: 54  RTPEIRGRRSSSRLSKREVSSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESP 113
           RTP  RGR S SR   R  S   S  +  +         G      P   R  R+RS +P
Sbjct: 607 RTPARRGR-SRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPA--RRGRSRSRTP 663

Query: 114 AVRTRNNNSVSSRERHRPSPRSTRGRQGRNHVDESPVEFPATRSLRRRATASAGTP 169
           A R R+ +   +R   R   R T  R+GR+           +RSL RR  + + TP
Sbjct: 664 ARRGRSRSRTPARRSGRSRSR-TPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTP 718



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 54/227 (23%), Positives = 91/227 (40%), Gaps = 45/227 (19%)

Query: 3    PSPEPPSLESMKGDTRHLNGEEDAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRR 62
            P P   S  S + + + L  + +  G E S+       DQ +         RTP   G+R
Sbjct: 1493 PRPRSRSPSSPELNNKCLTPQRERSGSESSV-------DQKT-------VARTP--LGQR 1536

Query: 63   SSSRLSKR-EVSSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFR----ETRTRSESPAVRT 117
            S S  S+  +V    S  +    D   +    + TP+  +       E  ++S     R+
Sbjct: 1537 SRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRS 1596

Query: 118  RNNNSVSSRERHRPSPRSTRGRQGRNHVDESP-VEFPATRSLRRRATASAGTP--WPSPP 174
            R+ +S   +++ R +PR+  G       D SP  + PA R+L RR+ + + +    PSP 
Sbjct: 1597 RSGSSPEVKDKPRAAPRAQSGS------DSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650

Query: 175  SSYLTIDLTDDTEDTHGTPQSSSTPYARLAQDSQQGGMESPQVEADS 221
             S         TE +   P  S T        +++G   SP+ +  S
Sbjct: 1651 GS-------SSTESSPEHPPKSRT--------ARRGSRSSPEPKTKS 1682



 Score = 30.0 bits (66), Expect = 9.4
 Identities = 31/117 (26%), Positives = 44/117 (37%), Gaps = 7/117 (5%)

Query: 54  RTPEIRGRRSSSRLSKREVSSLLSYTQDLTGDGDGEDGDGSDTPVMPKLFRET----RTR 109
           R  + RGR  S+R  +    S  +  +  +          S TP   +    T    R+R
Sbjct: 546 RNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605

Query: 110 SESPAVRTRNNNSVSSRERHR---PSPRSTRGRQGRNHVDESPVEFPATRSLRRRAT 163
           S +PA R R+ +   +R R R   P  R +R R        S    PA R   R  T
Sbjct: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT 662


>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform 2
            [Homo sapiens]
          Length = 1214

 Score = 38.5 bits (88), Expect = 0.026
 Identities = 59/263 (22%), Positives = 99/263 (37%), Gaps = 36/263 (13%)

Query: 25   DAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREVSSL--------- 75
            D  G+ DS     +  + S    P + +    E+ GRR+S   SK+   +          
Sbjct: 853  DKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEV-GRRTSVLFSKKNPKTAGPPKRPGRP 911

Query: 76   -LSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPSPR 134
              +    +T    G        P+M  L +  R RS  P+  + +++  S+ +   P   
Sbjct: 912  PKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDKSTEDP--PMDL 969

Query: 135  STRGRQGRNH-VDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGTP 193
               G  G N  V +S + +    SL R ++ S  +   S  SS    D T  T    G  
Sbjct: 970  PANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESS---SSSSSSAASDRTSTTPSKQGRG 1026

Query: 194  QSSSTPYARLAQDSQQ--GGMESPQVEADSGDGDS---------------SEYQDGKEFG 236
            + S +      +DS +   G E+      +G G                 SE +D     
Sbjct: 1027 KPSFSR-GTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDEDSPLDA 1085

Query: 237  IGDLVWGKIKGFSWWPAMVVSWK 259
            + DLVW K +G+  +PA+++  K
Sbjct: 1086 L-DLVWAKCRGYPSYPALIIDPK 1107


>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform 1
            [Homo sapiens]
          Length = 1220

 Score = 38.5 bits (88), Expect = 0.026
 Identities = 59/263 (22%), Positives = 99/263 (37%), Gaps = 36/263 (13%)

Query: 25   DAGGREDSILVNGACSDQSSDSPPILEAIRTPEIRGRRSSSRLSKREVSSL--------- 75
            D  G+ DS     +  + S    P + +    E+ GRR+S   SK+   +          
Sbjct: 859  DKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEV-GRRTSVLFSKKNPKTAGPPKRPGRP 917

Query: 76   -LSYTQDLTGDGDGEDGDGSDTPVMPKLFRETRTRSESPAVRTRNNNSVSSRERHRPSPR 134
              +    +T    G        P+M  L +  R RS  P+  + +++  S+ +   P   
Sbjct: 918  PKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDKSTEDP--PMDL 975

Query: 135  STRGRQGRNH-VDESPVEFPATRSLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGTP 193
               G  G N  V +S + +    SL R ++ S  +   S  SS    D T  T    G  
Sbjct: 976  PANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESS---SSSSSSAASDRTSTTPSKQGRG 1032

Query: 194  QSSSTPYARLAQDSQQ--GGMESPQVEADSGDGDS---------------SEYQDGKEFG 236
            + S +      +DS +   G E+      +G G                 SE +D     
Sbjct: 1033 KPSFSR-GTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDEDSPLDA 1091

Query: 237  IGDLVWGKIKGFSWWPAMVVSWK 259
            + DLVW K +G+  +PA+++  K
Sbjct: 1092 L-DLVWAKCRGYPSYPALIIDPK 1113


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 38.1 bits (87), Expect = 0.034
 Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 12/62 (19%)

Query: 462 DDDGY----QSYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCY 517
           D DGY    Q YC VC +G E++LC   +C R + + CL+         E   +  WSC 
Sbjct: 334 DGDGYETDHQDYCEVCQQGGEIILCD--TCPRAYHLVCLD------PELEKAPEGKWSCP 385

Query: 518 MC 519
            C
Sbjct: 386 HC 387



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 19/73 (26%), Positives = 30/73 (41%), Gaps = 8/73 (10%)

Query: 462 DDDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAAEAKLQEPWSCYMCLP 521
           ++D +  +C VC +G ELL C   +C   + + CL   +      E      W C  C  
Sbjct: 411 EEDDHMEFCRVCKDGGELLCCD--ACPSSYHLHCLNPPLPEIPNGE------WLCPRCTC 462

Query: 522 QRCHGVLRRRKDW 534
               G ++R   W
Sbjct: 463 PPLKGKVQRILHW 475


>gi|149192855 HLA-B associated transcript 2-like [Homo sapiens]
          Length = 2229

 Score = 37.4 bits (85), Expect = 0.059
 Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 21/105 (20%)

Query: 149  PVEFPATRSLRRRATASAGTPWPSPPSSYLT------IDLTDDTEDTHGTPQSSSTPYAR 202
            PV+ PA  S R+  TA + T   S    + +      +DL+ ++ ++  T    S+PY  
Sbjct: 1636 PVQAPANDSWRKAVTAFSSTETGSAEQGFKSSQGDSGVDLSAESRESSATSSQRSSPYGT 1695

Query: 203  LAQDSQQG-GMESP--------------QVEADSGDGDSSEYQDG 232
            L  +   G G+  P              Q +++ G G S E++ G
Sbjct: 1696 LKPEEMSGPGLAEPKADSHKEQAPKPSEQKDSEQGSGQSKEHRPG 1740


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,381,709
Number of Sequences: 37866
Number of extensions: 1738006
Number of successful extensions: 6071
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 103
Number of HSP's that attempted gapping in prelim test: 5769
Number of HSP's gapped (non-prelim): 356
length of query: 845
length of database: 18,247,518
effective HSP length: 111
effective length of query: 734
effective length of database: 14,044,392
effective search space: 10308583728
effective search space used: 10308583728
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.