BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|28558973 mediator complex subunit 14 [Homo sapiens] (1454 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|28558973 mediator complex subunit 14 [Homo sapiens] 2929 0.0 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 59 3e-08 gi|163965366 nascent polypeptide-associated complex alpha subuni... 57 1e-07 gi|222418647 mucin 7, secreted precursor [Homo sapiens] 56 2e-07 gi|222418649 mucin 7, secreted precursor [Homo sapiens] 56 2e-07 gi|222418645 mucin 7, secreted precursor [Homo sapiens] 56 2e-07 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 56 3e-07 gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 56 3e-07 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 55 4e-07 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 5e-07 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 55 5e-07 gi|116284392 mucin 2 precursor [Homo sapiens] 54 1e-06 gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 53 2e-06 gi|47132519 Ras association and pleckstrin homology domains 1 is... 53 2e-06 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 52 3e-06 gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 52 3e-06 gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 52 3e-06 gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 52 3e-06 gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 52 3e-06 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 52 3e-06 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 52 3e-06 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 52 3e-06 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 52 4e-06 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 52 4e-06 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 52 4e-06 gi|55750053 atrophin-1 [Homo sapiens] 52 5e-06 gi|55750041 atrophin-1 [Homo sapiens] 52 5e-06 gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 51 9e-06 gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transfera... 51 9e-06 gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 50 1e-05 >gi|28558973 mediator complex subunit 14 [Homo sapiens] Length = 1454 Score = 2929 bits (7592), Expect = 0.0 Identities = 1454/1454 (100%), Positives = 1454/1454 (100%) Query: 1 MAPVQLENHQLVPPGGGGGGSGGPPSAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLH 60 MAPVQLENHQLVPPGGGGGGSGGPPSAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLH Sbjct: 1 MAPVQLENHQLVPPGGGGGGSGGPPSAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLH 60 Query: 61 RAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISS 120 RAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISS Sbjct: 61 RAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISS 120 Query: 121 FLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPP 180 FLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPP Sbjct: 121 FLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPP 180 Query: 181 DPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDD 240 DPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDD Sbjct: 181 DPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDD 240 Query: 241 PDVPWRLLKLEILVEDKETGDGRALVHSMQISFIHQLVQSRLFADEKPLQDMYNCLHSFC 300 PDVPWRLLKLEILVEDKETGDGRALVHSMQISFIHQLVQSRLFADEKPLQDMYNCLHSFC Sbjct: 241 PDVPWRLLKLEILVEDKETGDGRALVHSMQISFIHQLVQSRLFADEKPLQDMYNCLHSFC 300 Query: 301 LSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIK 360 LSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIK Sbjct: 301 LSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIK 360 Query: 361 IDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAIL 420 IDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAIL Sbjct: 361 IDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAIL 420 Query: 421 RGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEK 480 RGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEK Sbjct: 421 RGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEK 480 Query: 481 SVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFI 540 SVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFI Sbjct: 481 SVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFI 540 Query: 541 KLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPAMALLLQQFKENIQDLVF 600 KLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPAMALLLQQFKENIQDLVF Sbjct: 541 KLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPAMALLLQQFKENIQDLVF 600 Query: 601 RTKTGKQTRTNAKRKLSDDPCPVESKKTKRAGEMCAFNKVLAHFVAMCDTNMPFVGLRLE 660 RTKTGKQTRTNAKRKLSDDPCPVESKKTKRAGEMCAFNKVLAHFVAMCDTNMPFVGLRLE Sbjct: 601 RTKTGKQTRTNAKRKLSDDPCPVESKKTKRAGEMCAFNKVLAHFVAMCDTNMPFVGLRLE 660 Query: 661 LSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGITEETQKALDRSLLDCTFRLQGRNNRTW 720 LSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGITEETQKALDRSLLDCTFRLQGRNNRTW Sbjct: 661 LSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGITEETQKALDRSLLDCTFRLQGRNNRTW 720 Query: 721 VAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECV 780 VAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECV Sbjct: 721 VAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECV 780 Query: 781 LEFARSLPDIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGP 840 LEFARSLPDIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGP Sbjct: 781 LEFARSLPDIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGP 840 Query: 841 NSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTA 900 NSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTA Sbjct: 841 NSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTA 900 Query: 901 YQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLK 960 YQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLK Sbjct: 901 YQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLK 960 Query: 961 TFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP 1020 TFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP Sbjct: 961 TFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP 1020 Query: 1021 LTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGP 1080 LTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGP Sbjct: 1021 LTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGP 1080 Query: 1081 GASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPD 1140 GASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPD Sbjct: 1081 GASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPD 1140 Query: 1141 ASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAG 1200 ASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAG Sbjct: 1141 ASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAG 1200 Query: 1201 SYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQT 1260 SYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQT Sbjct: 1201 SYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQT 1260 Query: 1261 LQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIM 1320 LQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIM Sbjct: 1261 LQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIM 1320 Query: 1321 KLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEP 1380 KLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEP Sbjct: 1321 KLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEP 1380 Query: 1381 VSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVR 1440 VSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVR Sbjct: 1381 VSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVR 1440 Query: 1441 DLMANLTLPPGGRP 1454 DLMANLTLPPGGRP Sbjct: 1441 DLMANLTLPPGGRP 1454 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 59.3 bits (142), Expect = 3e-08 Identities = 73/242 (30%), Positives = 98/242 (40%), Gaps = 31/242 (12%) Query: 973 ARRRSVNEDDNPPSPIGGDMMDSLISQL---QPPPQQQPFPKQPGTSGAYPLTSPPTSYH 1029 ARR + PSP + +++ +P P +P +P T G S S H Sbjct: 151 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSS-ASEH 206 Query: 1030 STVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHG 1089 ST SP+ S G G L+ P+ S + P S GP A +P Sbjct: 207 STTEPSPAARRRPSAG---------GGLQRPASRSLSSSATPLSSPARSGPSAR-GTPRA 256 Query: 1090 TLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPS-LHSPVPDASHSPRAG 1148 PS P P G P PQV+ P A P + P + S L +P P A SP A Sbjct: 257 PAHPSQP----KPKGLQALRP--PQVTPPRKDAA-PALGPLSSSPLATPSPSAPPSPSAP 309 Query: 1149 TSSQTMPTNMPPPRKLPQRSWAASIPTI-LTHSAL---NILLLPSPTPGLVPGLAGSYLC 1204 S QT+P+ PP Q + + PT+ THS L + L +P P P LA L Sbjct: 310 PSLQTLPS--PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 Query: 1205 SP 1206 +P Sbjct: 368 AP 369 Score = 50.4 bits (119), Expect = 1e-05 Identities = 52/215 (24%), Positives = 80/215 (37%), Gaps = 36/215 (16%) Query: 985 PSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSP 1044 P+ + ++ + S PP Q PF P + P +PP+ ++ P + P Sbjct: 389 PNALAVHLLQAPFSPPPSPPVQAPF-SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 447 Query: 1045 GNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSG 1104 A P S TPPP + P A P P +P + +P Sbjct: 448 --------------ASPPMSPSATPPPQAPPPLAAPPLQLAKP----PPQAPPALATP-- 487 Query: 1105 RAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPV-PDASHSPRA----GTSSQTMPTNMP 1159 P + PSP A PG +P +PS P+ P A+ P+A +P + P Sbjct: 488 --------PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539 Query: 1160 --PPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192 P + P+R T ++ L + L P P P Sbjct: 540 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574 Score = 46.2 bits (108), Expect = 2e-04 Identities = 60/220 (27%), Positives = 87/220 (39%), Gaps = 30/220 (13%) Query: 1003 PPQQQPFPKQP----GTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGA-- 1056 PPQ P K G + PL +P S + + PS+ SP A+ PS A Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP----PATPPSQATT 328 Query: 1057 -LRAPS-----------PASFVPTPPPSSH-GISIGPGASFASPHGT--LDPSSPYTMVS 1101 L +P+ P S + TPPP + +++ P + SP + L P + + + Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 388 Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMP-- 1159 P+ A + +P PSP + P PA+P + P A+ +A S P +P Sbjct: 389 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS---PSATPPSQAPPSLAAPPLQVPPS 445 Query: 1160 PPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLA 1199 PP P A P A L L P P P LA Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 485 Score = 43.9 bits (102), Expect = 0.001 Identities = 108/442 (24%), Positives = 145/442 (32%), Gaps = 57/442 (12%) Query: 1000 LQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059 L P P P P P T A + V + P + G + A+ P A RA Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAA----GAVGRKPL---AERAGGIGGATIPESAPRA 77 Query: 1060 -PSPASFVPTPPPSSHGISIGPGASFASPHGTLDP--SSPYTMVSPSGRAGNWPGSPQVS 1116 P+ S PP S G P A SP P +S T P G+ G + + Sbjct: 78 GPTRTS---RPPASGRG-ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133 Query: 1117 GPSPAARMPGMSP---------ANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPR-KLPQ 1166 A P S + P+ +P P + RA + +P P R + P Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193 Query: 1167 RSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMR--------- 1217 S+ + HS PSP P AG L P R L S Sbjct: 194 EGPRKSVSSASEHSTTE----PSPAARRRPS-AGGGLQRPASRSLSSSATPLSSPARSGP 248 Query: 1218 ------RHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAG 1271 R Q + L P V + DA AL P ++ L Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP---ALGPLSSSPLATPSPSAPPS 305 Query: 1272 QWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQ 1331 P LQ L + A PP +A T + L TH + L P QA Sbjct: 306 PSAPPSLQTLP----SPPATPPSQATTSLGSPTLQA--THSFLPSPPLSPLATPPPQAPP 359 Query: 1332 -LKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYD 1390 L PP++PP++P TP+ + + L L S PP PV P Sbjct: 360 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQ--APFSPP 416 Query: 1391 MASGTTQQADIPRQQNSSVAAP 1412 + + A P Q S+AAP Sbjct: 417 ASPPVSPSATPPSQAPPSLAAP 438 Score = 38.5 bits (88), Expect = 0.048 Identities = 48/174 (27%), Positives = 64/174 (36%), Gaps = 12/174 (6%) Query: 983 NPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042 +PP+ G S + L P P P+ P A L PP+ S Q+P T Sbjct: 494 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT- 552 Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSP-----Y 1097 PG + S P L A +P P PPPS S G A H + S+P Y Sbjct: 553 -PGPDTSVSGPRLTL-ALAPG---PPPPPSRSPSSTLSGPDLAG-HSSSATSTPEELRGY 606 Query: 1098 TMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSS 1151 G A + P +++ PAA G +P +P P G S Sbjct: 607 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 660 Score = 37.7 bits (86), Expect = 0.081 Identities = 54/224 (24%), Positives = 72/224 (32%), Gaps = 43/224 (19%) Query: 1002 PPPQQQPF---------PKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAAS- 1051 PPPQ P P P + PPT T P + +PG S Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578 Query: 1052 SPSGALRAPSPA---SFVPTPPPSSHGISIGP-GASFASPHGTLD------------PSS 1095 SPS L P A S + P G GP G + ASP + P+ Sbjct: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 638 Query: 1096 PYTMVSPSGRAGNWPGSP------------QVSGPSPAARMPGMSPANPSLHSPVPDASH 1143 P G WP + + GP A PG PS + A+ Sbjct: 639 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 698 Query: 1144 SPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLL 1187 AG SS++ P +L + A +++ H LLL Sbjct: 699 GAGAGASSRS-----PKQARLGELPLGALQASVVQHLLSRTLLL 737 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 57.4 bits (137), Expect = 1e-07 Identities = 68/234 (29%), Positives = 92/234 (39%), Gaps = 28/234 (11%) Query: 984 PPSPIGGDMMDSLISQLQP-----PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSM 1038 PPSP G S ++ L P PP++ P P +P P T Q+P++ Sbjct: 858 PPSPKGAPT-PSAVTPLSPKGVTLPPKETPTPSVVNLP--FPKEGPATP---APKQAPAL 911 Query: 1039 -MHTQSPGNLHAASSPSGALRAPSPASFVPTPP----PSSHGISIGPGASFA-SPHGTLD 1092 M + SP A +P G +PSP PTPP PS G P +A +P Sbjct: 912 SMTSSSPKKARATPAPKGIPASPSPKG-APTPPAATPPSPKGGPATPSPKWAPTPPAATP 970 Query: 1093 PSSPYTMVSPSGRAGNWPGSPQVSGPSP----AARMPGMSPANPSLHSPVPDASHSPRAG 1148 PS +PS + P P + PSP A P +P P++ P P S + Sbjct: 971 PSPKGGPATPSPKGA--PTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028 Query: 1149 TSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPG-LVPGLAGS 1201 + P PP P+ S AA+ P LPSP G P L G+ Sbjct: 1029 PKGASTPPAATPPS--PKGSPAAT-PLPKGAPTTPAATLPSPKGGPATPSLKGA 1079 Score = 56.6 bits (135), Expect = 2e-07 Identities = 74/254 (29%), Positives = 91/254 (35%), Gaps = 45/254 (17%) Query: 985 PSPIGGDMMDSLISQLQPPPQQQPFPK----QPGTSGAY--PLTSPP-------TSYHST 1031 PSP GG SL PP P PK P GA P +PP T H Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124 Query: 1032 VNQSPSMMHTQSPGNLHAASSPSGA-----LRAPSPASFVPTPPPSSHGISIGPGASFAS 1086 +P+ G L A P GA PSP + TPPP G P A+ S Sbjct: 1125 APTTPAATPPSPKGGL-ATPPPKGAPTTPAATPPSPKGGLATPPPK--GAPTTPAATPPS 1181 Query: 1087 PHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSP----AARMPGMSPANPSLHSPVPDAS 1142 P G L ++P SP G P +P + PSP A P +P P+ P P Sbjct: 1182 PKGGL--ATP----SPKGA----PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1231 Query: 1143 HSPRAGTSSQTMPTNMPPPRK----LPQRSWAASIPTILTHSALNILLLP----SPTPGL 1194 + + + T P PP K P A + P S L P +P P + Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAV 1291 Query: 1195 V--PGLAGSYLCSP 1206 V P G SP Sbjct: 1292 VTPPSPKGGPATSP 1305 Score = 55.5 bits (132), Expect = 4e-07 Identities = 70/258 (27%), Positives = 92/258 (35%), Gaps = 47/258 (18%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQS 1043 PPSP GG S PP P PK G+ A P ++ + SP + Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSPK--GSPAATPFPKGASTPPAATPPSPKGSPAAT 1050 Query: 1044 PGNLHAASSPSGALRAPS--PAS----FVPTPP-------------PSSHGISIGPGASF 1084 P A ++P+ L +P PA+ PTPP PS G + P A+ Sbjct: 1051 PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP 1110 Query: 1085 ASPHGTLD-------PSSPY-TMVSPSGRAGN-----WPGSPQVSGPSP----AARMPGM 1127 SP G L P++P T SP G P +P + PSP A P Sbjct: 1111 PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170 Query: 1128 SPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRK----LPQRSWAASIPTILTHSALN 1183 +P P+ P P + + + T P PP K P A + P S Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230 Query: 1184 ILLLPSP-----TPGLVP 1196 L PSP TP P Sbjct: 1231 GLATPSPKGAPTTPAATP 1248 Score = 49.7 bits (117), Expect = 2e-05 Identities = 64/240 (26%), Positives = 81/240 (33%), Gaps = 33/240 (13%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPK----QPGTSGA--YPLTSPPTSYHSTVNQSPS 1037 PPSP GG P P PK P GA P +PP+ SP Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215 Query: 1038 MMHTQSPGNLHAASSPSGALRAPSPASFVPTP---PPSSHGISIGPGASFA-SPHGTLDP 1093 T SP G L PSP TP PPS G P A +P P Sbjct: 1216 GAPTTPAAT---PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272 Query: 1094 SSPYTMVSPSGRAGNWP---------GSPQVSGPSPAARMPGMSPANP--SLHSPVPDAS 1142 S + +P + P G P S P A P +P +P S +P P + Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332 Query: 1143 HSPRAGT-----SSQTMPTNMPPPRKLPQRSWAASIPT----ILTHSALNILLLPSPTPG 1193 +P A T + T+P P + P + PT +H + PSP G Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392 Score = 42.4 bits (98), Expect = 0.003 Identities = 56/232 (24%), Positives = 90/232 (38%), Gaps = 51/232 (21%) Query: 1002 PPPQQQPFPKQPGTSGA--------YPLTSP----------------PTSYHSTVNQSPS 1037 P P++ P PKQ TS + P+ +P P+S + + + Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532 Query: 1038 MMHTQSPGNL---HAASSPSGALRAPSPASFVPTP-----PPSSHGISIGPGASFASPHG 1089 ++ ++P L A P+ + +P +PTP PSS S P + ++ G Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592 Query: 1090 TLDPSS---PYTMVSPSGRAGNWPGSPQVSGPS----PAARMPGMSPANPSL-HSPVPDA 1141 P P + SPS + P P V+ PS PA P +P +P + S + D+ Sbjct: 1593 APSPKELLIPPAVTSPSPKEA--PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS 1650 Query: 1142 SHSPRAGTSSQTMPTNMPPPRK-LPQRSWAASIPTILTHSALNILLLPSPTP 1192 SP + T M +P K LP + ++ +L A P TP Sbjct: 1651 PTSPASVTCK--MGATVPQASKGLPAKKGPTALKEVLVAPA------PESTP 1694 Score = 39.7 bits (91), Expect = 0.021 Identities = 60/237 (25%), Positives = 85/237 (35%), Gaps = 40/237 (16%) Query: 984 PPSPIGGDMMD--------------SLISQLQPPPQQ---QPFPKQPGTSGAYPLTSPPT 1026 PPSP GG SL L PP + P P + P TSPP Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK 1307 Query: 1027 SYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFAS 1086 + +P SP P GA P+P + PPS G P + +S Sbjct: 1308 GAPTPPAATPP-----SPKGSPGTPPPKGA---PTPPA---VTPPSPKGTPTLPATTPSS 1356 Query: 1087 PHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPS----PAARMPGMSPANPSLHSPVPDAS 1142 G PSS P+ + G P ++ PS PA P P +P++ P + Sbjct: 1357 KGGPTTPSSKEGPTPPAATPSH-KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415 Query: 1143 HSPRAGTSSQTMPT--NMPPPRKLP---QRSWAASIPT--ILTHSALNILLLPSPTP 1192 + P+ ++ PP P +++ A S P T S+ LP+ TP Sbjct: 1416 PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP 1472 Score = 38.9 bits (89), Expect = 0.036 Identities = 45/211 (21%), Positives = 76/211 (36%), Gaps = 16/211 (7%) Query: 955 PAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPP----QQQPFP 1010 PAP + ++ S P P + +S + P P Q+ Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747 Query: 1011 KQPGTSGAY----PLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFV 1066 G ++ PL P + + + + P + +++PS + P S V Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV 1807 Query: 1067 PTPPPSSHGISIGPGASFASPHGTLDPSSP---YTMVSPSGRAGNWP-GSPQVSGPSPAA 1122 PT PP + PG SP L P+ ++ P +G P S V+ P+P Sbjct: 1808 PTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTP-- 1865 Query: 1123 RMPGMSPANPSLHSPVPDASHSPRAGTSSQT 1153 + G+ PS PV ++ +GT S + Sbjct: 1866 KSAGIPVPTPSAKQPV--TKNNKGSGTESDS 1894 >gi|222418647 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 56.2 bits (134), Expect = 2e-07 Identities = 57/228 (25%), Positives = 86/228 (37%), Gaps = 30/228 (13%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061 PP P P +S T+ P + +T PS + P A +P AP Sbjct: 169 PPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSS--SAPPETTAAPPTPPATTPAPP 226 Query: 1062 PASFVP---TPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGP 1118 +S P PP+ + P +S A P T P +P S P Sbjct: 227 SSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTP---------------SATTLDP 271 Query: 1119 SPAARMPGMS--PANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTI 1176 S A+ P + P PS +P P +S +P+ T++ N P P S ++ PT Sbjct: 272 SSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTH 331 Query: 1177 LTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRII 1224 T +++ + P PG + + RFL + M+ L RII Sbjct: 332 QTTTSVTTQTTTTKQPTSAPGQ------NKISRFL--LYMKNLLNRII 371 Score = 33.5 bits (75), Expect = 1.5 Identities = 39/173 (22%), Positives = 59/173 (34%), Gaps = 16/173 (9%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG------NLHAASSPSG 1055 P P Q P +S P T S S S T P N SS Sbjct: 85 PNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSREN 144 Query: 1056 ALRAPSPASFVPTPPPSSHGISIGPGASFAS----PHGTLDPSSPYTMVSPSGRAGNWPG 1111 + S A+ P P+ + P A+ P + P + +PS P Sbjct: 145 VNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPS 204 Query: 1112 S---PQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPP 1161 S P+ + P P +PA PS +P P+ + +P +++ P + P Sbjct: 205 SSAPPETTAAPPTP--PATTPAPPSSSAP-PETTAAPPTPSATTPAPLSSSAP 254 Score = 31.2 bits (69), Expect = 7.6 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 1119 SPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP---TNMPPPRKLPQRSWAA 1171 SPA + +P PS +P P +S +P T++ P T PP P + AA Sbjct: 159 SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA 214 >gi|222418649 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 56.2 bits (134), Expect = 2e-07 Identities = 57/228 (25%), Positives = 86/228 (37%), Gaps = 30/228 (13%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061 PP P P +S T+ P + +T PS + P A +P AP Sbjct: 169 PPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSS--SAPPETTAAPPTPPATTPAPP 226 Query: 1062 PASFVP---TPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGP 1118 +S P PP+ + P +S A P T P +P S P Sbjct: 227 SSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTP---------------SATTLDP 271 Query: 1119 SPAARMPGMS--PANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTI 1176 S A+ P + P PS +P P +S +P+ T++ N P P S ++ PT Sbjct: 272 SSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTH 331 Query: 1177 LTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRII 1224 T +++ + P PG + + RFL + M+ L RII Sbjct: 332 QTTTSVTTQTTTTKQPTSAPGQ------NKISRFL--LYMKNLLNRII 371 Score = 33.5 bits (75), Expect = 1.5 Identities = 39/173 (22%), Positives = 59/173 (34%), Gaps = 16/173 (9%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG------NLHAASSPSG 1055 P P Q P +S P T S S S T P N SS Sbjct: 85 PNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSREN 144 Query: 1056 ALRAPSPASFVPTPPPSSHGISIGPGASFAS----PHGTLDPSSPYTMVSPSGRAGNWPG 1111 + S A+ P P+ + P A+ P + P + +PS P Sbjct: 145 VNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPS 204 Query: 1112 S---PQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPP 1161 S P+ + P P +PA PS +P P+ + +P +++ P + P Sbjct: 205 SSAPPETTAAPPTP--PATTPAPPSSSAP-PETTAAPPTPSATTPAPLSSSAP 254 Score = 31.2 bits (69), Expect = 7.6 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 1119 SPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP---TNMPPPRKLPQRSWAA 1171 SPA + +P PS +P P +S +P T++ P T PP P + AA Sbjct: 159 SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA 214 >gi|222418645 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 56.2 bits (134), Expect = 2e-07 Identities = 57/228 (25%), Positives = 86/228 (37%), Gaps = 30/228 (13%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061 PP P P +S T+ P + +T PS + P A +P AP Sbjct: 169 PPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSS--SAPPETTAAPPTPPATTPAPP 226 Query: 1062 PASFVP---TPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGP 1118 +S P PP+ + P +S A P T P +P S P Sbjct: 227 SSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTP---------------SATTLDP 271 Query: 1119 SPAARMPGMS--PANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTI 1176 S A+ P + P PS +P P +S +P+ T++ N P P S ++ PT Sbjct: 272 SSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTH 331 Query: 1177 LTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRII 1224 T +++ + P PG + + RFL + M+ L RII Sbjct: 332 QTTTSVTTQTTTTKQPTSAPGQ------NKISRFL--LYMKNLLNRII 371 Score = 33.5 bits (75), Expect = 1.5 Identities = 39/173 (22%), Positives = 59/173 (34%), Gaps = 16/173 (9%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG------NLHAASSPSG 1055 P P Q P +S P T S S S T P N SS Sbjct: 85 PNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSREN 144 Query: 1056 ALRAPSPASFVPTPPPSSHGISIGPGASFAS----PHGTLDPSSPYTMVSPSGRAGNWPG 1111 + S A+ P P+ + P A+ P + P + +PS P Sbjct: 145 VNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPS 204 Query: 1112 S---PQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPP 1161 S P+ + P P +PA PS +P P+ + +P +++ P + P Sbjct: 205 SSAPPETTAAPPTP--PATTPAPPSSSAP-PETTAAPPTPSATTPAPLSSSAP 254 Score = 31.2 bits (69), Expect = 7.6 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 1119 SPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP---TNMPPPRKLPQRSWAA 1171 SPA + +P PS +P P +S +P T++ P T PP P + AA Sbjct: 159 SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA 214 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 55.8 bits (133), Expect = 3e-07 Identities = 80/301 (26%), Positives = 122/301 (40%), Gaps = 47/301 (15%) Query: 986 SPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG 1045 S G ++ S+ L P P P SGA P S T +T +PS+ +Q+PG Sbjct: 1466 SASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLAT---APSLSSSQTPG 1522 Query: 1046 NLHAASSPSGALRAPSPASFVP----TPPPSSHGISIGPGASFASPHGTLDPSSP--YTM 1099 + L AP+ +S VP T P+ + + P ++ ASP + +P ++ Sbjct: 1523 H--------PLLLAPT-SSHVPGLNSTVAPACSPVLV-PASALASPFPSAPNPAPAQASL 1572 Query: 1100 VSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAG---TSSQTMPT 1156 ++P+ A +P +P + SPA P +P+P + SP A SSQT P Sbjct: 1573 LAPASSASQALATPLAPMAAPQTAILAPSPAPPL--APLPVLAPSPGAAPVLASSQT-PV 1629 Query: 1157 NMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIM 1216 + P P S A++ P +P+PTP L P + L +P+ L S Sbjct: 1630 PVMAPSSTPGTSLASASP------------VPAPTPVLAPSSTQTMLPAPVPSPLPSPAS 1677 Query: 1217 RRHLQRI----------IQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVT 1266 + L +TL L N G +T +L +L P QTL L Sbjct: 1678 TQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPG 1737 Query: 1267 P 1267 P Sbjct: 1738 P 1738 Score = 48.1 bits (113), Expect = 6e-05 Identities = 65/232 (28%), Positives = 91/232 (39%), Gaps = 37/232 (15%) Query: 995 SLISQLQPPPQQQPFPKQPGTSGAYPLTSP-PT--SYHSTVNQ-SPSMMHTQSPGNLHAA 1050 +LI + P P P P ++ P T+P PT S NQ P+M++ + Sbjct: 1258 ALIQAVAPTPGPTPVSVLPSST---PSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVR 1314 Query: 1051 SSPSGALRAPSPASFVPTPPPSSHGISIGPGASFAS---PHGTLD----PSSPYTMVSPS 1103 +P L P + P PP S + P + P TL P T+V P Sbjct: 1315 QAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPL 1374 Query: 1104 GRAGNWPGSPQVSGPSPAA---------RMPGMSPANPSLHSPVPDASH--SPRAGTSSQ 1152 + + P SP+VS +P A +P P S P+P++S SP + T S Sbjct: 1375 LKLVHSP-SPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSV 1433 Query: 1153 --------TMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVP 1196 ++PT +P P P I LT SA LL S TP L P Sbjct: 1434 PLSSSLPISVPTTLPAPASAP---LTIPISAPLTVSASGPALLTSVTPPLAP 1482 Score = 43.5 bits (101), Expect = 0.001 Identities = 48/185 (25%), Positives = 68/185 (36%), Gaps = 39/185 (21%) Query: 1007 QPFPKQPGTS-----------GAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSG 1055 QP PKQ G + G P+ PP S +P + P +L ++SP+G Sbjct: 999 QPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSA-QPTPGPVPQVLPASLMVSASPAG 1057 Query: 1056 -----ALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWP 1110 A R P P P P S + P + GT P +P + P+ Sbjct: 1058 PPLIPASRPPGPVLLPPLQPNSGSLPQVLP-SPLGVLSGTSRPPTPTLSLKPTP------ 1110 Query: 1111 GSPQVSGPSPAARMPGMSPANPSLHSPV---PDASHSPRAGTSSQTMP-----TNMPPPR 1162 P+P P P + SL P+ P + P A T++ T T +P P Sbjct: 1111 -------PAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPT 1163 Query: 1163 KLPQR 1167 PQR Sbjct: 1164 PAPQR 1168 Score = 40.8 bits (94), Expect = 0.010 Identities = 61/228 (26%), Positives = 86/228 (37%), Gaps = 32/228 (14%) Query: 1008 PFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALR-----APSP 1062 PFP P + A P S S +P + +P A SP+ L APSP Sbjct: 1558 PFPSAPNPAPAQASLLAPASSASQALATP-LAPMAAPQTAILAPSPAPPLAPLPVLAPSP 1616 Query: 1063 -------ASFVPTP---PPSSHGISIGPGASFASPHGTLDPSSPYTMV-SPSGRAGNWPG 1111 +S P P P S+ G S+ + +P L PSS TM+ +P P Sbjct: 1617 GAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPA 1676 Query: 1112 SPQ--VSGPSPAARMPGMSPA--------NPSLHSPVPDASHSPRAG---TSSQTMPTNM 1158 S Q P+ A + G SP+ NP P S +P + T +QT+ Sbjct: 1677 STQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAP 1736 Query: 1159 PPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSP 1206 PP Q A P + S + P+ T L P + + L +P Sbjct: 1737 GPPLGPTQTLSLAPAPPLAPASPVG--PAPAHTLTLAPASSSASLLAP 1782 Score = 38.9 bits (89), Expect = 0.036 Identities = 52/199 (26%), Positives = 69/199 (34%), Gaps = 27/199 (13%) Query: 976 RSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQS 1035 RS++ ++ P PIGG + S L PPQQ ++ G SP Sbjct: 2794 RSMSGPESSP-PIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSP----------- 2841 Query: 1036 PSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDP-S 1094 G L A + P+ R P +P + G+ P ++ DP Sbjct: 2842 -----ENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVP 2896 Query: 1095 SPYTMV--SPSGRAGNWPGSPQVSGPSPAAR-MPGMSPANPSLHSPVPDASHSPRAGTSS 1151 P T++ P PG PQ GP P R P +SP P A P GT S Sbjct: 2897 GPETLIVADPVLEPQLIPG-PQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTIS 2955 Query: 1152 QTMPTN-----MPPPRKLP 1165 N PPP P Sbjct: 2956 SAGDGNSESRTQPPPHPSP 2974 >gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] Length = 464 Score = 55.8 bits (133), Expect = 3e-07 Identities = 51/171 (29%), Positives = 69/171 (40%), Gaps = 25/171 (14%) Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062 PP P PG P PPTS V+ +H +PG P+ + P+P Sbjct: 303 PPAPGVHPPAPGVHPPAPGVHPPTS---GVHPPAPGVHPPAPG----VHPPAPGVHPPAP 355 Query: 1063 ASFVPTP---PPSSHGISI-GPGASFASPHGTLDPSSPYTMVSPSGRAGNWPG-SPQVSG 1117 P P PP S G+ PG A+P + P +P G PG PQ G Sbjct: 356 GVHPPAPGVHPPPSAGVHPQAPGVHPAAP--AVHPQAPGVHPPAPGMHPQAPGVHPQPPG 413 Query: 1118 PSPAA-----RMPGMSPANPSLH--SPVPDASHSPRAGTSSQTMPTNMPPP 1161 P+A + PG+ P+NP +H +P+P P P N+PPP Sbjct: 414 VHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEG----PGNIPPP 460 Score = 48.5 bits (114), Expect = 5e-05 Identities = 46/170 (27%), Positives = 58/170 (34%), Gaps = 19/170 (11%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061 PPP P +P + P PP + P A S P G + P Sbjct: 234 PPPLMNGLPPRPPLPESLP--PPPPG---------GLPLPPMPPTGPAPSGPPGPPQLPP 282 Query: 1062 PASFVPTPPPSSHGISIG---PGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGP 1118 PA V P P H + G P P + P +P SG P +P V P Sbjct: 283 PAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVH---PPAPGVHPP 339 Query: 1119 SPAAR--MPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQ 1166 +P PG+ P P +H P P P AG Q + P PQ Sbjct: 340 APGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQ 389 Score = 30.8 bits (68), Expect = 9.9 Identities = 25/80 (31%), Positives = 31/80 (38%), Gaps = 11/80 (13%) Query: 1000 LQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059 + PPP P+ PG A P P V+ MH Q+PG P G Sbjct: 364 VHPPPSAGVHPQAPGVHPAAPAVHPQA---PGVHPPAPGMHPQAPG---VHPQPPGV--H 415 Query: 1060 PSPASFVPTPP---PSSHGI 1076 PS P PP PS+ G+ Sbjct: 416 PSAPGVHPQPPGVHPSNPGV 435 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 55.5 bits (132), Expect = 4e-07 Identities = 54/198 (27%), Positives = 73/198 (36%), Gaps = 28/198 (14%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061 PPP Q P P P GA Q+P + +P A++P L+ P Sbjct: 727 PPPAQDPAPATPVAKGA-----------GLGPQAPDSQASPAPAPQIPAAAP---LKGPG 772 Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPA 1121 P+S P H +G SPH T PS P + R + P P Sbjct: 773 PSS----SPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAP 828 Query: 1122 ARMPGMSPANPSLHSPVPDASHSPRAGTSSQ--TMPTNMPPPRKLPQRSWAASIPTILTH 1179 +PG+ L P P ++ +P A Q P + PP LP A +P T Sbjct: 829 PTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPP---APHLPPSSTS 885 Query: 1180 SAL-----NILLLPSPTP 1192 SA+ LP+PTP Sbjct: 886 SAVASSSETSSRLPAPTP 903 Score = 53.9 bits (128), Expect = 1e-06 Identities = 67/240 (27%), Positives = 95/240 (39%), Gaps = 65/240 (27%) Query: 1002 PPPQQQPFPKQPGTSGA--YPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059 PPP P P PG P + PP + +P + + + + ++S S L A Sbjct: 844 PPPASNPAPTAPGPPQPPLRPQSQPP---EGPLPPAPHLPPSSTSSAVASSSETSSRLPA 900 Query: 1060 PSPASF------------VPTPPPSSHGISIGPGASFASPHGTLD------PSSPYTMV- 1100 P+P+ F PTPPP+ H + P A P T P+ P Sbjct: 901 PTPSDFQLQFPPSQGPHKSPTPPPTLHLVP-EPAAPPPPPPRTFQMVTTPFPALPQPKAL 959 Query: 1101 ------SPSG-----RAGNWPGSPQVS---GP--SPAA------RMPGMSPANPSLHSPV 1138 PSG +AG P +PQ S GP SPAA + P +P PS H+P Sbjct: 960 LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPS-HAPA 1018 Query: 1139 PDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGL 1198 P +P A T +PP +++A+++PT LN+ S PG GL Sbjct: 1019 P----APMAA-------TGLPPLLPAENKAFASNLPT------LNVAKAASSGPGKPSGL 1061 Score = 43.1 bits (100), Expect = 0.002 Identities = 53/219 (24%), Positives = 79/219 (36%), Gaps = 33/219 (15%) Query: 999 QLQPPPQQ---QPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMM------HTQSPGNL-- 1047 Q PPQ QP P + L PP++ + + S+ +Q P + Sbjct: 654 QAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEG 713 Query: 1048 -HAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRA 1106 H + S + AP PA P + G +GP A P + SP+ A Sbjct: 714 PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQA-------------PDSQASPA-PA 759 Query: 1107 GNWPGSPQVSGPSPAA--RMPGMSPANPSLHSPVPDASHSPRAGTS---SQTMPTNMPPP 1161 P + + GP P++ +P +P S H P P + P S S + P + PP Sbjct: 760 PQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPL 819 Query: 1162 RKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAG 1200 P ++P I N L +P P P G Sbjct: 820 HPCPPPQAPPTLPGIFV--IQNQLGVPPPASNPAPTAPG 856 Score = 37.4 bits (85), Expect = 0.11 Identities = 49/217 (22%), Positives = 77/217 (35%), Gaps = 44/217 (20%) Query: 1020 PLTSPPTSYHSTVNQSPSMMHT------QSPGNLHAASSPSGALRAPSPASFVPTPPPSS 1073 P+ +P + HS S + + Q P +L A S P+ + AP+ Sbjct: 528 PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPA------------ 575 Query: 1074 HGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPS 1133 GP A+ TL PS+ + +P G + +P + A P+ Sbjct: 576 -----GPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630 Query: 1134 LHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPG 1193 + +P+P P+A PP PQ AA+ P T P P+PG Sbjct: 631 VSTPLPLGLQQPQA---------QQPPQAPTPQ---AAAPPQATT---------PQPSPG 669 Query: 1194 LVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQ 1230 L L P +++ + LQ + QE Q Sbjct: 670 LASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ 706 Score = 32.7 bits (73), Expect = 2.6 Identities = 43/205 (20%), Positives = 71/205 (34%), Gaps = 26/205 (12%) Query: 1003 PPQQQPFPKQP-GTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061 P Q QP P P T+ +T PP++ +M++T P L ++P+ A + Sbjct: 567 PTQSQPAPAGPAATTVLQGVTLPPSAV--------AMLNT--PDGLVQPATPAAATGEAA 616 Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSP---------YTMVSPSGRAGNWP-- 1110 P V P + +S P P +P T PS + P Sbjct: 617 PVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEK 676 Query: 1111 ---GSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQR 1167 G P + P+ + P S P ++ P + + + PPP + P Sbjct: 677 IVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVI-VSAPPPAQDPAP 735 Query: 1168 SWAASIPTILTHSALNILLLPSPTP 1192 + + L A + P+P P Sbjct: 736 ATPVAKGAGLGPQAPDSQASPAPAP 760 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 55.1 bits (131), Expect = 5e-07 Identities = 60/213 (28%), Positives = 87/213 (40%), Gaps = 36/213 (16%) Query: 984 PPSPIGGDMMDSLISQLQPP------PQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPS 1037 PP+ + +++L S PP P P + P PL +PP+ + ++PS Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585 Query: 1038 MMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSS-HGISIGPGASFASPHGTLDPSSP 1096 + T P A +SP P S + TPPP + +++ P + SP + P SP Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS-PPLSP 644 Query: 1097 YTMVSPSGRAGNW------------PGSPQVSGP---------SPAARMPGMSPANPSLH 1135 + +PS +A N P SP V P SP+A P +P PSL Sbjct: 645 --LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP--PSLA 700 Query: 1136 SPVPDASHSPRAG---TSSQTMPTNMPPPRKLP 1165 +P SP A + S T P PPP P Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733 Score = 53.9 bits (128), Expect = 1e-06 Identities = 78/254 (30%), Positives = 98/254 (38%), Gaps = 52/254 (20%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVN-QSP---SMM 1039 PPSP+ ++ S PPPQ P P G L SPP S +T Q+P ++ Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPPLQG---LPSPPLSPLATPPPQAPPXLALP 628 Query: 1040 HTQSPGNLHAASSPSGALRAPSP------------ASFVPTP---------PPSSHGISI 1078 Q+P + AS P L PSP A F P P PP+S +S Sbjct: 629 PLQAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS- 686 Query: 1079 GPGA--------SFASPHGTLDPSSPYT-MVSPSGRAGNWPGSPQVSGPSPAARMPGMSP 1129 P A S A+P + PS P + +SPS +P P P A P P Sbjct: 687 -PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS-------ATPPPQAPPPLAAPPLQVP 738 Query: 1130 ANPSLHSPV-PDASHSPRAGTSSQTMPTNMP--PPRKLPQRSWAASIPTILTHSALNIL- 1185 +P P+ P A+ PR P +P PP LP A P A L Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798 Query: 1186 LLPSPTPGLVPGLA 1199 LPSP P PG A Sbjct: 799 ALPSP-PASFPGQA 811 Score = 53.5 bits (127), Expect = 1e-06 Identities = 58/233 (24%), Positives = 96/233 (41%), Gaps = 28/233 (12%) Query: 985 PSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSP 1044 P+ + ++ + S PP Q PF P + P +PP+ ++ P + P Sbjct: 653 PNALAVHLLQAPFSPPPSPPVQAPF-SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711 Query: 1045 GNLHAASSPSGALRAPSPASF----VPTPPPSSHGISIGPGAS--------FASPHGTLD 1092 + + S + +AP P + VP PP+S +S P A+ A+P + Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS--PSATPPPRVPPLLAAPPLQVP 769 Query: 1093 PSSPYTM-----VSPSGRAGNWPGSPQVSG-PSPAARMPGMSPANPSLHSPV-PDASHSP 1145 PS P ++ P +A +P + PSP A PG +P +PS P+ P A+ P Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829 Query: 1146 RA----GTSSQTMPTNMP--PPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192 +A +P + P P + P+R T ++ L + L P P P Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882 Score = 53.1 bits (126), Expect = 2e-06 Identities = 114/441 (25%), Positives = 158/441 (35%), Gaps = 51/441 (11%) Query: 1003 PPQQQPFPKQPGTSGAYPLTSPP--TSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAP 1060 PPQ P P++ PL+S P T S P + L A PS L P Sbjct: 282 PPQVTP-PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP 340 Query: 1061 SP-ASFVPTPPPSSHGISIGPGA--SFASPHGTLDP--SSPYTMVSPSGRAGNWPGSPQV 1115 P A P+ PPS + P S A P T P + P P + + SP + Sbjct: 341 LPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL 400 Query: 1116 SGPSPAARMPGMSPANPSLHSPVPDASHS-----PRAGTSSQTMPTNMPPPRKLPQRSWA 1170 P + + A SL SP A+HS PR +S T P+ P P S Sbjct: 401 QAPPSPLALSSLQ-ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR---PASTPPDSPP 456 Query: 1171 ASIPTILTHSA-LNILLLPSPTPGLVPGLAGSYLCSPLERF--LGSVIMRRHLQRIIQQE 1227 P L S L L P+ +P L+ PL+ L S + L +I Sbjct: 457 LQAPLSLPASPPLQTSLSPAVSP-----LSSPLTIHPLQALSSLASHSPQAPLSSLIMPP 511 Query: 1228 TLQLINSNEPGVIM-----FKTDALKCRVALSPKTNQTLQLKVTPENAG----------Q 1272 L+ +S P + T L+ +L+P QT +T + Q Sbjct: 512 -LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQ 570 Query: 1273 WKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQ- 1331 P L + +A PP +A +A L G P+ L L P QA Sbjct: 571 APPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP------LATPPPQAPPX 624 Query: 1332 LKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDM 1391 L PP++PP++P TP+ + + L L S PP PV P Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQ--APFSPPA 681 Query: 1392 ASGTTQQADIPRQQNSSVAAP 1412 + + A P Q S+AAP Sbjct: 682 SPPVSPSATPPSQAPPSLAAP 702 Score = 52.8 bits (125), Expect = 2e-06 Identities = 110/460 (23%), Positives = 162/460 (35%), Gaps = 75/460 (16%) Query: 973 ARRRSVNEDDNPPSPIGGDMMDSLISQL---QPPPQQQPFPKQPGTSGAYPLTSPPTSYH 1029 ARR + PSP + +++ +P P +P +P T G S S H Sbjct: 160 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSS-ASEH 215 Query: 1030 STVNQSP------------------SMMHTQSPGNLHAASSPS--GALRAPS-PASFVPT 1068 ST SP S+ + +P + A S PS G RAP+ P+ P Sbjct: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275 Query: 1069 PPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMS 1128 + + P A+P SSP SPSG P P + +P +P Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR-PVPPPDNAATP---LPATL 331 Query: 1129 PANPSLHSPVPDASHSPRAGTSSQTM-------PTNMPPPRKLPQRSWAASIPTI----L 1177 P +P L +P+P A SP A S QT+ P+ PP P S+ TI + Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQV 391 Query: 1178 THSALNILLLPSPTPGLVPGL-AGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNE 1236 HS + L P+P + L A + L SP + S L +Q L + + Sbjct: 392 PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS-----FLTMSPRQTQASLTSPSR 446 Query: 1237 PGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFE---------- 1286 P D+ + LS + LQ ++P + P + L+ Sbjct: 447 PA--STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL 504 Query: 1287 TRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSA 1346 + + PP + + +A L P + LE P A LT P Sbjct: 505 SSLIMPPLETQSSLAPPSLQTPPASLTTP-----PLENLPSLAPPPLQTASAPLTTPHLE 559 Query: 1347 PPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVP 1386 P P P S + T+ PP+ P SI P Sbjct: 560 TPPCPAPCPLQAPPSPL---------TTPPPETPSSIATP 590 Score = 38.5 bits (88), Expect = 0.048 Identities = 48/174 (27%), Positives = 64/174 (36%), Gaps = 12/174 (6%) Query: 983 NPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042 +PP+ G S + L P P P+ P A L PP+ S Q+P T Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT- 860 Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSP-----Y 1097 PG + S P L A +P P PPPS S G A H + S+P Y Sbjct: 861 -PGPDTSVSGPRLTL-ALAPG---PPPPPSRSPSSTLSGPDLAG-HSSSATSTPEELRGY 914 Query: 1098 TMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSS 1151 G A + P +++ PAA G +P +P P G S Sbjct: 915 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 968 Score = 37.7 bits (86), Expect = 0.081 Identities = 54/224 (24%), Positives = 72/224 (32%), Gaps = 43/224 (19%) Query: 1002 PPPQQQPF---------PKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAAS- 1051 PPPQ P P P + PPT T P + +PG S Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 886 Query: 1052 SPSGALRAPSPA---SFVPTPPPSSHGISIGP-GASFASPHGTLD------------PSS 1095 SPS L P A S + P G GP G + ASP + P+ Sbjct: 887 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 946 Query: 1096 PYTMVSPSGRAGNWPGSP------------QVSGPSPAARMPGMSPANPSLHSPVPDASH 1143 P G WP + + GP A PG PS + A+ Sbjct: 947 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 1006 Query: 1144 SPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLL 1187 AG SS++ P +L + A +++ H LLL Sbjct: 1007 GAGAGASSRS-----PKQARLGELPLGALQASVVQHLLSRTLLL 1045 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 55.1 bits (131), Expect = 5e-07 Identities = 47/172 (27%), Positives = 71/172 (41%), Gaps = 18/172 (10%) Query: 1003 PPQQQPFPKQPGT--SGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAP 1060 PP P+ P T A PL PP+ + S+ P + P ++ + RAP Sbjct: 749 PPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAP 808 Query: 1061 SPASFVPTPPPS-----SHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGS--P 1113 P + P P+ ++ +G + HG + SSPY V P+ P + P Sbjct: 809 GPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVV--SSPYVGVGPAPPVAGLPSAPPP 866 Query: 1114 QVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLP 1165 Q SGP A + + S+ +P+P SH T+ + PT PPP P Sbjct: 867 QFSGPELAMAVRPATTTVDSIQAPIP--SH-----TAPRPNPTPAPPPPCFP 911 Score = 49.7 bits (117), Expect = 2e-05 Identities = 44/140 (31%), Positives = 56/140 (40%), Gaps = 22/140 (15%) Query: 1000 LQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059 L PP P+ QPG G PP H+ + P+ Q P H SGAL Sbjct: 991 LLPPQSPYPYAPQPGVLG-----QPPPPLHTQLYPGPA----QDPLPAH-----SGALPF 1036 Query: 1060 PSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPS 1119 PSP P PP ++ GP S P G ++P T+ PS + P V P+ Sbjct: 1037 PSPGPPQPPHPP----LAYGPAPS-TRPMG--PQAAPLTIRGPSSAGQSTPSPHLVPSPA 1089 Query: 1120 PAARMPGMSPANPSLHSPVP 1139 P+ PG P P P P Sbjct: 1090 PSPG-PGPVPPRPPAAEPPP 1108 Score = 45.8 bits (107), Expect = 3e-04 Identities = 52/189 (27%), Positives = 62/189 (32%), Gaps = 20/189 (10%) Query: 1001 QPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAP 1060 QP P QP P Q G P P H P + Q+PG L S AP Sbjct: 954 QPQPHPQPHPSQ--AFGPQPPQQPLPLQH------PHLFPPQAPGLLPPQSPYP---YAP 1002 Query: 1061 SPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSP 1120 P PPP + GP H P PS P P GP+P Sbjct: 1003 QPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPF-------PSPGPPQPPHPPLAYGPAP 1055 Query: 1121 AARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHS 1180 + R G A ++ P +P P+ P P +P R AA P L Sbjct: 1056 STRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPS--PGPGPVPPRPPAAEPPPCLRRG 1113 Query: 1181 ALNILLLPS 1189 A LL S Sbjct: 1114 AAAADLLSS 1122 Score = 38.9 bits (89), Expect = 0.036 Identities = 52/218 (23%), Positives = 79/218 (36%), Gaps = 30/218 (13%) Query: 992 MMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAAS 1051 ++D + + PP P P P + + + P + + P + Sbjct: 707 LLDRELKKKPPPRPTAPKPLLPRREESEAVEA---------GDPPEELRSLPPDMVAGPR 757 Query: 1052 SPSGALRAPSPASFVPTPPPSSHGISIGPGASFAS---PHGTLDPSSPYTMVSPSGRAGN 1108 P L + +P F P+P PS S GPG + S P GT S P ++ P RA Sbjct: 758 LPDTFLGSATPLHFPPSPFPS----STGPGPHYLSGPLPPGTY--SGPTQLIQP--RAPG 809 Query: 1109 WPGSPQVSGPS--PA-------ARMPGMSPANPSLHSPVPDASHSPR-AGTSSQTMPTNM 1158 P GP+ PA +P SP + + SP +P AG S P Sbjct: 810 PHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFS 869 Query: 1159 PPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVP 1196 P + R ++ +I + P+PTP P Sbjct: 870 GPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPP 907 Score = 36.6 bits (83), Expect = 0.18 Identities = 50/187 (26%), Positives = 63/187 (33%), Gaps = 29/187 (15%) Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPP----------------PSSHGISIGPGASFA 1085 Q+P H A P+ P P VP P P+ H S G A F Sbjct: 888 QAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFP 947 Query: 1086 SPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSP 1145 +P P P+ PS G P PQ P P P P L P ++P Sbjct: 948 APRIGPQP-QPHPQPHPSQAFG--PQPPQ--QPLPLQHPHLFPPQAPGLLPPQSPYPYAP 1002 Query: 1146 RAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCS 1205 + G Q PPP Q + + HS L PSP P P +Y + Sbjct: 1003 QPGVLGQ------PPPPLHTQLYPGPAQDPLPAHS--GALPFPSPGPPQPPHPPLAYGPA 1054 Query: 1206 PLERFLG 1212 P R +G Sbjct: 1055 PSTRPMG 1061 Score = 35.8 bits (81), Expect = 0.31 Identities = 38/150 (25%), Positives = 51/150 (34%), Gaps = 12/150 (8%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQS 1043 P + G L +QL P P Q P P G +P PP H + P+ + Sbjct: 1002 PQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGAL-PFPSPGPPQPPHPPLAYGPA--PSTR 1058 Query: 1044 PGNLHAA----SSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM 1099 P AA PS A ++ VP+P PS GPG P P Sbjct: 1059 PMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSP-----GPGPVPPRPPAAEPPPCLRRG 1113 Query: 1100 VSPSGRAGNWPGSPQVSGPSPAARMPGMSP 1129 + + + P S SP P + P Sbjct: 1114 AAAADLLSSSPESQHGGTQSPGGGQPLLQP 1143 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 53.5 bits (127), Expect = 1e-06 Identities = 56/202 (27%), Positives = 74/202 (36%), Gaps = 15/202 (7%) Query: 1002 PPPQQQPFPKQPGTSGAYPLT--SPPTSYHS--TVNQSPSMMHTQSPGNLHAASSPSGAL 1057 PPP P P T+ P T SPPT+ S T SP T +P S P+ Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507 Query: 1058 RAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM-VSPSGRAGNWPGSPQVS 1116 P PAS PP ++ P + +P T PS P T ++P P + S Sbjct: 1508 ITP-PASTTTLPPTTTPS---PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1563 Query: 1117 GPSPAARMPG--MSPANPSLHSPVPDA----SHSPRAGTSSQTMPTNMPPPRKLPQRSWA 1170 P P +P+ P+ +P P + P S T T PPP P Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTT 1623 Query: 1171 ASIPTILTHSALNILLLPSPTP 1192 I + + L PSP P Sbjct: 1624 TPITPPTSTTTLPPTTTPSPPP 1645 Score = 52.8 bits (125), Expect = 2e-06 Identities = 50/177 (28%), Positives = 70/177 (39%), Gaps = 19/177 (10%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061 PPP P P T+ P T+P +T P+ T SP ++PS PS Sbjct: 1432 PPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTT--TPSP----PTTTPSPPTTTPS 1485 Query: 1062 PASFVPTPPPSSHGIS------IGPGASFASPHGTLDPSSPYTMVS--PSGRAGNWPGSP 1113 P + T PP + S I P AS + T PS P T + P + P + Sbjct: 1486 PPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1545 Query: 1114 QVSGPSPAARMPGM---SPANPSLHSPVPDASHSPRAGT--SSQTMPTNMPPPRKLP 1165 ++ P+ +P SP + +P P + SP T S T+ T PPP P Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602 Score = 52.0 bits (123), Expect = 4e-06 Identities = 54/190 (28%), Positives = 67/190 (35%), Gaps = 24/190 (12%) Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062 PP P P T+ P T+P S +T +P T SP + P +P P Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTP--SPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP-P 1457 Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAA 1122 S TPPP++ SP T PS P T SP P P + PSP Sbjct: 1458 ISTTTTPPPTTT----------PSPP-TTTPSPPTTTPSPPTTTTTTP--PPTTTPSP-- 1502 Query: 1123 RMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSAL 1182 P +P P P + P S T T PPP P I + + L Sbjct: 1503 --PTTTPITP----PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL 1556 Query: 1183 NILLLPSPTP 1192 PSP P Sbjct: 1557 PPTTTPSPPP 1566 Score = 51.6 bits (122), Expect = 5e-06 Identities = 56/219 (25%), Positives = 75/219 (34%), Gaps = 17/219 (7%) Query: 985 PSPIGGDMMDSLISQLQPPPQQQPFPKQ--PGTSGAYPLTSPPTSYHS---TVNQSPSMM 1039 PSP + PPP P P P T A T PPT+ S T +P Sbjct: 1477 PSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT 1536 Query: 1040 HTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPS----- 1094 T SP + P+ P + P+PPP++ + P + SP T PS Sbjct: 1537 TTPSPPTTTPITPPTSTTTLPPTTT--PSPPPTT--TTTPPPTTTPSPPTTTTPSPPTIT 1592 Query: 1095 --SPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQ 1152 +P +PS P + PSP P P + + P S P T+ Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1652 Query: 1153 TMPTNMPPPRKLPQRS-WAASIPTILTHSALNILLLPSP 1190 T PP P + P T + I PSP Sbjct: 1653 PTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSP 1691 Score = 48.5 bits (114), Expect = 5e-05 Identities = 53/203 (26%), Positives = 82/203 (40%), Gaps = 29/203 (14%) Query: 997 ISQLQPPPQQQPFPKQPGTSGAYPLT--SPPTSYHSTVNQSPSMMH-TQSPGNLHAASSP 1053 I+ PPP P P T+ P T SPPT+ T S + + T +P ++ Sbjct: 1591 ITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1650 Query: 1054 SGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSP 1113 PSP + TP P P + +P T PSSP T +PS P + Sbjct: 1651 PPPTTTPSPPTTT-TPSP--------PITTTTTPPPTTTPSSPIT-TTPS------PPTT 1694 Query: 1114 QVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASI 1173 ++ PSP +P++P + P ++ +P ++ T P+ P P + ++ Sbjct: 1695 TMTTPSPTT-----TPSSPITTTTTPSSTTTPSPPPTTMTTPS--PTTTPSPPTTTMTTL 1747 Query: 1174 PTILTHSALNILLLPSPTPGLVP 1196 P T S L LP P + P Sbjct: 1748 PPTTTSSPLTTTPLP---PSITP 1767 Score = 43.1 bits (100), Expect = 0.002 Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 12/144 (8%) Query: 1057 LRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVS 1116 + PSP + P+PPP+S ++ P + + P T P T SP P P + Sbjct: 1396 ITTPSPPTTTPSPPPTS-TTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP--PPTT 1452 Query: 1117 GPSP-----AARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRK----LPQR 1167 PSP P +P+ P+ P + SP T++ PT P P P Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512 Query: 1168 SWAASIPTILTHSALNILLLPSPT 1191 S PT P PT Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPT 1536 Score = 38.9 bits (89), Expect = 0.036 Identities = 37/155 (23%), Positives = 58/155 (37%), Gaps = 34/155 (21%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061 PP P P T+ P T+P + +T + + M T SP SSP PS Sbjct: 1659 PPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT--TPSSPITTTTTPS 1716 Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPA 1121 ++ P+PPP+ + +P T PS P T ++ Sbjct: 1717 -STTTPSPPPT----------TMTTPSPTTTPSPPTTTMT-------------------- 1745 Query: 1122 ARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPT 1156 +P + ++P +P+P + P S T PT Sbjct: 1746 -TLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPT 1779 Score = 37.4 bits (85), Expect = 0.11 Identities = 46/195 (23%), Positives = 75/195 (38%), Gaps = 21/195 (10%) Query: 1013 PGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPS 1072 P +G T+ P + +TV +P+ TQ+ H +++P L +P TP S Sbjct: 4165 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTS 4224 Query: 1073 SHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANP 1132 S P + TL P+ T +P P +P + P+ + +SP Sbjct: 4225 RSTSS--PLTESTTLLSTLPPAIEMTSTAP-------PSTP--TAPTTTSGGHTLSPPPS 4273 Query: 1133 SLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192 + SP + G+SS P P + + +A PT S +I+ T Sbjct: 4274 TTTSPPGTPTRGTTTGSSS------APTPSTVQTTTTSAWTPTPTPLSTPSII----RTT 4323 Query: 1193 GLVPGLAGSYLCSPL 1207 GL P + +C L Sbjct: 4324 GLRPYPSSVLICCVL 4338 Score = 32.3 bits (72), Expect = 3.4 Identities = 23/83 (27%), Positives = 32/83 (38%), Gaps = 5/83 (6%) Query: 1109 WPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRS 1168 WP ++ PSP P SP S + P + SP T++ PT P P P + Sbjct: 1390 WPMDKCITTPSPPTTTP--SPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSP---PITT 1444 Query: 1169 WAASIPTILTHSALNILLLPSPT 1191 PT ++ P PT Sbjct: 1445 TTTPPPTTTPSPPISTTTTPPPT 1467 >gi|7662236 TSC22 domain family, member 2 [Homo sapiens] Length = 780 Score = 53.1 bits (126), Expect = 2e-06 Identities = 71/282 (25%), Positives = 115/282 (40%), Gaps = 30/282 (10%) Query: 984 PPSPIG-GDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042 P P G + + ++ LQPP P QP ++GA + + Q+ S + Q Sbjct: 371 PVQPSGQSEYLQQHVAGLQPPS-----PAQPSSTGAAASPATAATLPVGTGQNASSVGAQ 425 Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPS-SPYTMVS 1101 G A+S PS A+ P P+ G + P P T+ P + Sbjct: 426 LMG---ASSQPSEAM--------APRTGPAQGG-QVAPCQPTGVPPATVGGVVQPCLGPA 473 Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPG----MSPANPSLHSPVPDASHSPRAGTSSQTMPTN 1157 +G+ + P PQ+ G P + +PG + P P++ + VP A P T+S TMP N Sbjct: 474 GAGQPQSVP-PPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVP-APSVPSVSTTSVTMP-N 530 Query: 1158 MPPP----RKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGS 1213 +P P ++L + + +I+ H L + P +P S + + +G Sbjct: 531 VPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQ 590 Query: 1214 VIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSP 1255 V R + Q L LI N+P V D+L + L+P Sbjct: 591 VDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTP 632 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 52.8 bits (125), Expect = 2e-06 Identities = 56/204 (27%), Positives = 75/204 (36%), Gaps = 31/204 (15%) Query: 985 PSPIGGDMMDSLISQLQPPPQQQPFP---KQPGTSGAYPLTSPPTSYHSTVNQSPSMMHT 1041 P+P + +++Q PP P P KQP +Y SPPT V P + Sbjct: 786 PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP---PVPVPPPTLPK 842 Query: 1042 QSPGNLHAASSPSGALRAPS-----PASFVPTP-PPSSHGISIGPGASFASPHGTLDPSS 1095 Q + A PS PS + F P P PP+ + P + +P S Sbjct: 843 QQ--SFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQ-----SP 895 Query: 1096 PYTMVSPSGRAGNWP-----------GSPQVSGPSPAARMPGMSPANPSLHSPVPDASHS 1144 P P + + P S V P P + +P P P SP PD S S Sbjct: 896 PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGS 955 Query: 1145 PRAGTSSQTMPTNMPPPRKLPQRS 1168 P TS + P PP PQR+ Sbjct: 956 PGKKTSKTSSPGGKKPP-PTPQRN 978 Score = 42.7 bits (99), Expect = 0.003 Identities = 45/182 (24%), Positives = 64/182 (35%), Gaps = 29/182 (15%) Query: 984 PPSPIGG--DMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHT 1041 PPSP+ ++ + SQ PPP +PP + P+ + Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPP------------------TPPAMESQPLKPVPANVAP 892 Query: 1042 QSPGNLHAASS--PSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM 1099 QSP + A PS ++ PSP F P PP SS P + +P P P Sbjct: 893 QSPPAVKAKPKWQPS-SIPVPSP-DFPPPPPESSLVFPPPPPSPVPAP-----PPPPPPT 945 Query: 1100 VSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMP 1159 SP+ PG SP + P +P S A H S ++ + Sbjct: 946 ASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFT 1005 Query: 1160 PP 1161 PP Sbjct: 1006 PP 1007 Score = 40.4 bits (93), Expect = 0.013 Identities = 47/201 (23%), Positives = 70/201 (34%), Gaps = 41/201 (20%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061 PPP P P PG++ A +P + P + ++ + P+ P Sbjct: 710 PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI 769 Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPA 1121 PA P PP P + +P T + T +P P+P Sbjct: 770 PAPLPPQAPPK-------PLVTIPAPTSTKTVAPVVTQAAP---------------PTPT 807 Query: 1122 ARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSA 1181 +P P+ P AS+ P S T P +PPP Q+S+ A P S Sbjct: 808 PPVP------PAKKQPAFPASYIP---PSPPTPPVPVPPPTLPKQQSFCAKPPP----SP 854 Query: 1182 LNILLLPSPTPGLVPGLAGSY 1202 L SP P +V +A + Sbjct: 855 L------SPVPSVVKQIASQF 869 Score = 31.2 bits (69), Expect = 7.6 Identities = 38/153 (24%), Positives = 53/153 (34%), Gaps = 16/153 (10%) Query: 1048 HAASSPSGALRAPSPASFVPTPP--------PSSHGISIGPGASFASPHGTLDPSSPYTM 1099 + AS PS L P P P PP PS S G A + T+ + Sbjct: 619 YTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTI--TRLQNA 676 Query: 1100 VSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMP 1159 SG P P + S ++ + P N + P P +Q P Sbjct: 677 SQHSGALFKPPTPPVMQSQSVKPQI--LVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA 734 Query: 1160 PPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192 P LPQ ++A P + H +I + PTP Sbjct: 735 P--SLPQ--FSAPPPPLKIHQVQHITQVAPPTP 763 Score = 30.8 bits (68), Expect = 9.9 Identities = 35/134 (26%), Positives = 53/134 (39%), Gaps = 8/134 (5%) Query: 1032 VNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTL 1091 +N ++ T+S + + SS S +++ S +S +P S+H G S P G + Sbjct: 511 MNYQEALKRTESAYDWTSLSSSS--IKSGSSSSSIPESQ-SNHSNQSDSGVSDTQPAGHV 567 Query: 1092 DPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSS 1151 S + V W Q+ S ARM M+ SL P+ T+S Sbjct: 568 RSQSIVSSVFSEA----WKRGTQLE-ESSKARMESMNRPYTSLVPPLSPQPKIVTPYTAS 622 Query: 1152 QTMPTNMPPPRKLP 1165 Q P PPP P Sbjct: 623 QPSPPLPPPPPPPP 636 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 52.4 bits (124), Expect = 3e-06 Identities = 75/266 (28%), Positives = 104/266 (39%), Gaps = 49/266 (18%) Query: 973 ARRRSVNEDDNPPSPIGGDMMDSLISQL---QPPPQQQPFPKQPGTSGAYPLTSPPTSYH 1029 ARR + PSP + +++ +P P +P +P T G S S H Sbjct: 160 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSS-ASEH 215 Query: 1030 STVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHG 1089 ST SP+ S G G L+ P+ S + P S GP A +P Sbjct: 216 STTEPSPAARRRPSAG---------GGLQRPASRSLSSSATPLSSPARSGPSAR-GTPRA 265 Query: 1090 TLDPSSPY---------TMVSPSGR-----AGNWPGSPQVSGPSPAARM----PGMSPAN 1131 PS P V+P + G SP ++ PSP+A + P PA Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-LATPSPSAALQSQAPPTLPAT 324 Query: 1132 P-------SLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTI-LTHSAL- 1182 P L +P+P A SP A S QT+P+ PP Q + + PT+ THS L Sbjct: 325 PHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS--PPATPPSQATTSLGSPTLQATHSFLP 382 Query: 1183 --NILLLPSPTPGLVPGLAGSYLCSP 1206 + L +P P P LA L +P Sbjct: 383 SPPLSPLATPPPQAPPALALPPLQAP 408 Score = 50.4 bits (119), Expect = 1e-05 Identities = 52/215 (24%), Positives = 80/215 (37%), Gaps = 36/215 (16%) Query: 985 PSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSP 1044 P+ + ++ + S PP Q PF P + P +PP+ ++ P + P Sbjct: 428 PNALAVHLLQAPFSPPPSPPVQAPF-SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486 Query: 1045 GNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSG 1104 A P S TPPP + P A P P +P + +P Sbjct: 487 --------------ASPPMSPSATPPPQAPPPLAAPPLQLAKP----PPQAPPALATP-- 526 Query: 1105 RAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPV-PDASHSPRA----GTSSQTMPTNMP 1159 P + PSP A PG +P +PS P+ P A+ P+A +P + P Sbjct: 527 --------PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578 Query: 1160 --PPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192 P + P+R T ++ L + L P P P Sbjct: 579 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613 Score = 47.0 bits (110), Expect = 1e-04 Identities = 61/220 (27%), Positives = 78/220 (35%), Gaps = 17/220 (7%) Query: 984 PPSPIGGDMMDSLISQLQPP-PQQQPFPKQPGTSGAYPLT-SPPTSYHSTVNQSPSMMHT 1041 PP+ SL QL P P P P P + P + P S +T SP++ T Sbjct: 318 PPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 377 Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVS 1101 S S P L P P + P P + SP T P +P + Sbjct: 378 HS----FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433 Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMP-- 1159 +A P SP PSP + P PA+P + P A+ +A S P +P Sbjct: 434 HLLQA---PFSPP---PSPPVQAPFSPPASPPVS---PSATPPSQAPPSLAAPPLQVPPS 484 Query: 1160 PPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLA 1199 PP P A P A L L P P P LA Sbjct: 485 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 524 Score = 44.3 bits (103), Expect = 9e-04 Identities = 54/193 (27%), Positives = 77/193 (39%), Gaps = 22/193 (11%) Query: 1004 PQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPA 1063 P+ P QP G L PP + +P++ S + A SPS AL++ +P Sbjct: 263 PRAPAHPSQPKPKGLQALR-PPQVTPPRKDAAPALGPLSS--SPLATPSPSAALQSQAPP 319 Query: 1064 SFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAAR 1123 + TP SS + A P + PS T+ SP P +P PS A Sbjct: 320 TLPATPHSSSLTCQLATPLPLAPPSPSAPPSL-QTLPSP-------PATP----PSQATT 367 Query: 1124 MPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAA------SIPTIL 1177 G SP + HS +P SP A Q P PP + P A+ + P+ Sbjct: 368 SLG-SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 426 Query: 1178 THSALNILLLPSP 1190 +AL + LL +P Sbjct: 427 APNALAVHLLQAP 439 Score = 43.1 bits (100), Expect = 0.002 Identities = 104/430 (24%), Positives = 147/430 (34%), Gaps = 61/430 (14%) Query: 1011 KQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP-------- 1062 + GTS P + PP S ++P +T SPG + + SG R P P Sbjct: 81 RSAGTSSRNPASRPPASGRG--ERAPPAKNT-SPGPVSSPGRASGTTR-PGPLGQKGLRI 136 Query: 1063 ------ASFVPTPPPSSHGISIGPGASFASPH-GTLDPSSPYTMVSPSGRAGNWPGSPQV 1115 A T P +S G + P GT P+ M S AG G P+ Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA----MARRSRAAGTEVGLPRP 192 Query: 1116 SG---PSPAARMPGMSPANPSLHS---PVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSW 1169 + P P P S ++ S HS P P A P AG Q P R L + Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR-----PASRSLSSSAT 247 Query: 1170 AASIPTILTHSALNILLLPS----PTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQ 1225 S P SA P+ P P + L + P + + + Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP-RKDAAPALGPLSSSPLAT 306 Query: 1226 QETLQLINSNEPGVIMFK--TDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEK 1283 + S P + + +L C++A L + P + P LQ L Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATP--------LPLAPPSPSA--PPSLQTLP- 355 Query: 1284 FFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQ-LKWNVQFCLTI 1342 + A PP +A T + L TH + L P QA L Sbjct: 356 ---SPPATPPSQATTSLGSPTLQA--THSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410 Query: 1343 PPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIP 1402 PP++PP++P TP+ + + L L S PP PV P + + A P Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQ--APFSPPASPPVSPSATPP 467 Query: 1403 RQQNSSVAAP 1412 Q S+AAP Sbjct: 468 SQAPPSLAAP 477 Score = 38.5 bits (88), Expect = 0.048 Identities = 48/174 (27%), Positives = 64/174 (36%), Gaps = 12/174 (6%) Query: 983 NPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042 +PP+ G S + L P P P+ P A L PP+ S Q+P T Sbjct: 533 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT- 591 Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSP-----Y 1097 PG + S P L A +P P PPPS S G A H + S+P Y Sbjct: 592 -PGPDTSVSGPRLTL-ALAPG---PPPPPSRSPSSTLSGPDLAG-HSSSATSTPEELRGY 645 Query: 1098 TMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSS 1151 G A + P +++ PAA G +P +P P G S Sbjct: 646 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 699 Score = 37.7 bits (86), Expect = 0.081 Identities = 54/224 (24%), Positives = 72/224 (32%), Gaps = 43/224 (19%) Query: 1002 PPPQQQPF---------PKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAAS- 1051 PPPQ P P P + PPT T P + +PG S Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617 Query: 1052 SPSGALRAPSPA---SFVPTPPPSSHGISIGP-GASFASPHGTLD------------PSS 1095 SPS L P A S + P G GP G + ASP + P+ Sbjct: 618 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 677 Query: 1096 PYTMVSPSGRAGNWPGSP------------QVSGPSPAARMPGMSPANPSLHSPVPDASH 1143 P G WP + + GP A PG PS + A+ Sbjct: 678 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 737 Query: 1144 SPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLL 1187 AG SS++ P +L + A +++ H LLL Sbjct: 738 GAGAGASSRS-----PKQARLGELPLGALQASVVQHLLSRTLLL 776 >gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 52.4 bits (124), Expect = 3e-06 Identities = 55/197 (27%), Positives = 71/197 (36%), Gaps = 29/197 (14%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP--LTSPPTSYHSTVNQSPSMMHT 1041 PP P G D + PP P P P T+ P L PP S P ++ Sbjct: 143 PPGPAPGPPQD-----ISEPPGGSPLPSPPSTAPPPPPLLLEPPPP-PSMAPPPPPVLEA 196 Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVS 1101 SP H SSPS P+P F+P PP + P +P P + T + Sbjct: 197 LSPP--HTLSSPS----IPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLF 250 Query: 1102 PSGRAGNWPGSPQVSGPSPAA--RMPGMSPANP--SLHSPVPDASHSPRAGTSSQTMPTN 1157 P G W ++G A P SPA P S P P+ T P + Sbjct: 251 PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE---------PHLTFPRS 301 Query: 1158 MPPPRKLPQRSWAASIP 1174 P P R+ +SIP Sbjct: 302 FKVPPPTPVRT--SSIP 316 Score = 32.3 bits (72), Expect = 3.4 Identities = 51/192 (26%), Positives = 70/192 (36%), Gaps = 29/192 (15%) Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVN-QSPSMMHTQSPGNLHAASSPSGALRAPS 1061 PP+ P +P S P P ++ + P+ + T S A +P A Sbjct: 276 PPRS---PAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332 Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM-----VSP---------SGRAG 1107 A PPS H I P AS P +P P + SP RAG Sbjct: 333 KAPSRLPLPPSFH---IRP-ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAG 388 Query: 1108 NWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHS--PRAG---TSSQTMPTNMPPPR 1162 P +P + P PA +P +P P P+P A + P AG T + P P P Sbjct: 389 TPPPAPPL--PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446 Query: 1163 KLPQRSWAASIP 1174 + A+S P Sbjct: 447 PPSPENTASSAP 458 Score = 31.2 bits (69), Expect = 7.6 Identities = 44/192 (22%), Positives = 68/192 (35%), Gaps = 32/192 (16%) Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062 PP+ P P P + +P T P +T+ + + T P ++P A P+ Sbjct: 642 PPKATPEPAIPPKATLWPATPP----KATLGPATPLKATSGP------TTPLKATSGPAI 691 Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGS-----PQVSG 1117 AS T P ++ + + P G + + + +PS G S P Sbjct: 692 ASTATTLPTTTSQLM---AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGA 748 Query: 1118 PSPAARMPGMSPAN---PSLHSPVPDASH-----------SPRAGTSSQTMPTNMPPPRK 1163 S AA P SP P L+ P S R G + P + P Sbjct: 749 RSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPG 808 Query: 1164 LPQRSWAASIPT 1175 LP + A++ PT Sbjct: 809 LPAKPPASAQPT 820 >gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 52.4 bits (124), Expect = 3e-06 Identities = 55/197 (27%), Positives = 71/197 (36%), Gaps = 29/197 (14%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP--LTSPPTSYHSTVNQSPSMMHT 1041 PP P G D + PP P P P T+ P L PP S P ++ Sbjct: 143 PPGPAPGPPQD-----ISEPPGGSPLPSPPSTAPPPPPLLLEPPPP-PSMAPPPPPVLEA 196 Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVS 1101 SP H SSPS P+P F+P PP + P +P P + T + Sbjct: 197 LSPP--HTLSSPS----IPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLF 250 Query: 1102 PSGRAGNWPGSPQVSGPSPAA--RMPGMSPANP--SLHSPVPDASHSPRAGTSSQTMPTN 1157 P G W ++G A P SPA P S P P+ T P + Sbjct: 251 PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE---------PHLTFPRS 301 Query: 1158 MPPPRKLPQRSWAASIP 1174 P P R+ +SIP Sbjct: 302 FKVPPPTPVRT--SSIP 316 Score = 32.3 bits (72), Expect = 3.4 Identities = 51/192 (26%), Positives = 70/192 (36%), Gaps = 29/192 (15%) Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVN-QSPSMMHTQSPGNLHAASSPSGALRAPS 1061 PP+ P +P S P P ++ + P+ + T S A +P A Sbjct: 276 PPRS---PAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332 Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM-----VSP---------SGRAG 1107 A PPS H I P AS P +P P + SP RAG Sbjct: 333 KAPSRLPLPPSFH---IRP-ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAG 388 Query: 1108 NWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHS--PRAG---TSSQTMPTNMPPPR 1162 P +P + P PA +P +P P P+P A + P AG T + P P P Sbjct: 389 TPPPAPPL--PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446 Query: 1163 KLPQRSWAASIP 1174 + A+S P Sbjct: 447 PPSPENTASSAP 458 Score = 31.2 bits (69), Expect = 7.6 Identities = 44/192 (22%), Positives = 68/192 (35%), Gaps = 32/192 (16%) Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062 PP+ P P P + +P T P +T+ + + T P ++P A P+ Sbjct: 642 PPKATPEPAIPPKATLWPATPP----KATLGPATPLKATSGP------TTPLKATSGPAI 691 Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGS-----PQVSG 1117 AS T P ++ + + P G + + + +PS G S P Sbjct: 692 ASTATTLPTTTSQLM---AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGA 748 Query: 1118 PSPAARMPGMSPAN---PSLHSPVPDASH-----------SPRAGTSSQTMPTNMPPPRK 1163 S AA P SP P L+ P S R G + P + P Sbjct: 749 RSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPG 808 Query: 1164 LPQRSWAASIPT 1175 LP + A++ PT Sbjct: 809 LPAKPPASAQPT 820 >gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens] Length = 1188 Score = 52.4 bits (124), Expect = 3e-06 Identities = 55/197 (27%), Positives = 71/197 (36%), Gaps = 29/197 (14%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP--LTSPPTSYHSTVNQSPSMMHT 1041 PP P G D + PP P P P T+ P L PP S P ++ Sbjct: 143 PPGPAPGPPQD-----ISEPPGGSPLPSPPSTAPPPPPLLLEPPPP-PSMAPPPPPVLEA 196 Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVS 1101 SP H SSPS P+P F+P PP + P +P P + T + Sbjct: 197 LSPP--HTLSSPS----IPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLF 250 Query: 1102 PSGRAGNWPGSPQVSGPSPAA--RMPGMSPANP--SLHSPVPDASHSPRAGTSSQTMPTN 1157 P G W ++G A P SPA P S P P+ T P + Sbjct: 251 PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE---------PHLTFPRS 301 Query: 1158 MPPPRKLPQRSWAASIP 1174 P P R+ +SIP Sbjct: 302 FKVPPPTPVRT--SSIP 316 Score = 32.3 bits (72), Expect = 3.4 Identities = 51/192 (26%), Positives = 70/192 (36%), Gaps = 29/192 (15%) Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVN-QSPSMMHTQSPGNLHAASSPSGALRAPS 1061 PP+ P +P S P P ++ + P+ + T S A +P A Sbjct: 276 PPRS---PAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332 Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM-----VSP---------SGRAG 1107 A PPS H I P AS P +P P + SP RAG Sbjct: 333 KAPSRLPLPPSFH---IRP-ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAG 388 Query: 1108 NWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHS--PRAG---TSSQTMPTNMPPPR 1162 P +P + P PA +P +P P P+P A + P AG T + P P P Sbjct: 389 TPPPAPPL--PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446 Query: 1163 KLPQRSWAASIP 1174 + A+S P Sbjct: 447 PPSPENTASSAP 458 Score = 31.2 bits (69), Expect = 7.6 Identities = 44/192 (22%), Positives = 68/192 (35%), Gaps = 32/192 (16%) Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062 PP+ P P P + +P T P +T+ + + T P ++P A P+ Sbjct: 642 PPKATPEPAIPPKATLWPATPP----KATLGPATPLKATSGP------TTPLKATSGPAI 691 Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGS-----PQVSG 1117 AS T P ++ + + P G + + + +PS G S P Sbjct: 692 ASTATTLPTTTSQLM---AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGA 748 Query: 1118 PSPAARMPGMSPAN---PSLHSPVPDASH-----------SPRAGTSSQTMPTNMPPPRK 1163 S AA P SP P L+ P S R G + P + P Sbjct: 749 RSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPG 808 Query: 1164 LPQRSWAASIPT 1175 LP + A++ PT Sbjct: 809 LPAKPPASAQPT 820 >gi|21237805 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2 isoform a [Homo sapiens] Length = 1214 Score = 52.4 bits (124), Expect = 3e-06 Identities = 70/220 (31%), Positives = 88/220 (40%), Gaps = 36/220 (16%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPF-PKQPGTSGAYPLTSPPTSYHSTV---NQS--PS 1037 PP +G P QQQP QPG A P PP H NQ PS Sbjct: 1003 PPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPG---AVPPGVPPPGPHGPSPFPNQQTPPS 1059 Query: 1038 MMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPY 1097 MM PG+ H P A AP F PPP SI P G+L S Sbjct: 1060 MMPGAVPGSGH----PGVAGNAPLGLPFGMPPPPPPPAPSI-------IPFGSLADSISI 1108 Query: 1098 TMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTN 1157 + +P G+ P G P +P +S ANP LH +P ++ TMP++ Sbjct: 1109 NLPAPPNLHGHHHHLPFAPGTLPPPNLP-VSMANP-LHPNLP----------ATTTMPSS 1156 Query: 1158 MPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPG 1197 +P L S AA P I+ +A+ LLPS +P PG Sbjct: 1157 LPLGPGL--GSAAAQSPAIV--AAVQGNLLPSASPLPDPG 1192 Score = 51.2 bits (121), Expect = 7e-06 Identities = 34/116 (29%), Positives = 47/116 (40%), Gaps = 17/116 (14%) Query: 1070 PPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQ---VSGPSPAARMPG 1126 PP+ HG+++ P + +P G+ P G+AG+ G Q P P A PG Sbjct: 980 PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPG 1039 Query: 1127 MSPANPSLHSP--------------VPDASHSPRAGTSSQTMPTNMPPPRKLPQRS 1168 + P P SP VP + H AG + +P MPPP P S Sbjct: 1040 VPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAGNAPLGLPFGMPPPPPPPAPS 1095 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 52.4 bits (124), Expect = 3e-06 Identities = 66/233 (28%), Positives = 86/233 (36%), Gaps = 38/233 (16%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPK-QPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042 PPSP PPP P P QP T A ++P + Q P H+ Sbjct: 257 PPSP-------------HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSL 303 Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGIS-IGPGASFASPHGTLDPSSPYTMVS 1101 G L L+ P P PP +S G + +G + A PH +L + S Sbjct: 304 QAGPL---------LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA-----S 349 Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPGMSP--ANPSLHSPVPDA-SHSPR-AGTSSQTMPTN 1157 S P Q P+P A MP + P P P P A H P +G S +M N Sbjct: 350 QSALQSQQPPREQPLPPAPLA-MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 408 Query: 1158 MPPPRKL-PQRSWAASIPTILTHSALNILLLPSP---TPGLVPGLAGSYLCSP 1206 +PPP L P S + P L ++ P +P PGL S P Sbjct: 409 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 461 Score = 50.1 bits (118), Expect = 2e-05 Identities = 64/215 (29%), Positives = 85/215 (39%), Gaps = 30/215 (13%) Query: 999 QLQPPPQQQPFPKQPGTSGAYP----LTSP-PTSYHSTVNQSPSMMHTQSPGNLHAASSP 1053 Q QPP Q P P S A P L +P PT + V S +Q+P A ++P Sbjct: 181 QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 240 Query: 1054 --------SGALRAPSPASFVPTPPPSSH-------GISIGPGA-SFASP--HGTLDPSS 1095 + AL P S P P PS H G + P A S A P HG P Sbjct: 241 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ-GPPG 299 Query: 1096 PYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP 1155 P+++ +G PG PQ G P A G +P SP H+ +SQ+ Sbjct: 300 PHSL--QAGPLLQHPGPPQPFGLPPQASQ-GQAPLGT---SPAAAYPHTSLQLPASQSAL 353 Query: 1156 TNMPPPRKLPQRSWAASIPTILTHSALNILLLPSP 1190 + PPR+ P ++P I I LP+P Sbjct: 354 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 388 Score = 38.9 bits (89), Expect = 0.036 Identities = 39/142 (27%), Positives = 48/142 (33%), Gaps = 23/142 (16%) Query: 1000 LQPPPQQQPFPKQPGTSGAY---------PLTSPPTSYHSTVNQSPSMMHTQSPGNLHAA 1050 LQ PQ QP P P P + PPT H Q P H PG Sbjct: 434 LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI 493 Query: 1051 SSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHG---TLDPSSPYTMVSPSGRAG 1107 + P+ PS ++ PP+ G S P S A+ G S P V A Sbjct: 494 TPPT----CPSTST-----PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEAL 544 Query: 1108 NWPGSPQVSGPSPAARMPGMSP 1129 + P+ P P R P P Sbjct: 545 DDAEEPE--SPPPPPRSPSPEP 564 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 52.4 bits (124), Expect = 3e-06 Identities = 66/233 (28%), Positives = 86/233 (36%), Gaps = 38/233 (16%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPK-QPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042 PPSP PPP P P QP T A ++P + Q P H+ Sbjct: 811 PPSP-------------HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSL 857 Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGIS-IGPGASFASPHGTLDPSSPYTMVS 1101 G L L+ P P PP +S G + +G + A PH +L + S Sbjct: 858 QAGPL---------LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA-----S 903 Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPGMSP--ANPSLHSPVPDA-SHSPR-AGTSSQTMPTN 1157 S P Q P+P A MP + P P P P A H P +G S +M N Sbjct: 904 QSALQSQQPPREQPLPPAPLA-MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962 Query: 1158 MPPPRKL-PQRSWAASIPTILTHSALNILLLPSP---TPGLVPGLAGSYLCSP 1206 +PPP L P S + P L ++ P +P PGL S P Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 1015 Score = 50.1 bits (118), Expect = 2e-05 Identities = 64/215 (29%), Positives = 85/215 (39%), Gaps = 30/215 (13%) Query: 999 QLQPPPQQQPFPKQPGTSGAYP----LTSP-PTSYHSTVNQSPSMMHTQSPGNLHAASSP 1053 Q QPP Q P P S A P L +P PT + V S +Q+P A ++P Sbjct: 735 QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 794 Query: 1054 --------SGALRAPSPASFVPTPPPSSH-------GISIGPGA-SFASP--HGTLDPSS 1095 + AL P S P P PS H G + P A S A P HG P Sbjct: 795 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ-GPPG 853 Query: 1096 PYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP 1155 P+++ +G PG PQ G P A G +P SP H+ +SQ+ Sbjct: 854 PHSL--QAGPLLQHPGPPQPFGLPPQASQ-GQAPLGT---SPAAAYPHTSLQLPASQSAL 907 Query: 1156 TNMPPPRKLPQRSWAASIPTILTHSALNILLLPSP 1190 + PPR+ P ++P I I LP+P Sbjct: 908 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 942 Score = 38.9 bits (89), Expect = 0.036 Identities = 39/142 (27%), Positives = 48/142 (33%), Gaps = 23/142 (16%) Query: 1000 LQPPPQQQPFPKQPGTSGAY---------PLTSPPTSYHSTVNQSPSMMHTQSPGNLHAA 1050 LQ PQ QP P P P + PPT H Q P H PG Sbjct: 988 LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI 1047 Query: 1051 SSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHG---TLDPSSPYTMVSPSGRAG 1107 + P+ PS ++ PP+ G S P S A+ G S P V A Sbjct: 1048 TPPT----CPSTST-----PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEAL 1098 Query: 1108 NWPGSPQVSGPSPAARMPGMSP 1129 + P+ P P R P P Sbjct: 1099 DDAEEPE--SPPPPPRSPSPEP 1118 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 52.4 bits (124), Expect = 3e-06 Identities = 66/233 (28%), Positives = 86/233 (36%), Gaps = 38/233 (16%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPK-QPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042 PPSP PPP P P QP T A ++P + Q P H+ Sbjct: 811 PPSP-------------HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSL 857 Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGIS-IGPGASFASPHGTLDPSSPYTMVS 1101 G L L+ P P PP +S G + +G + A PH +L + S Sbjct: 858 QAGPL---------LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA-----S 903 Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPGMSP--ANPSLHSPVPDA-SHSPR-AGTSSQTMPTN 1157 S P Q P+P A MP + P P P P A H P +G S +M N Sbjct: 904 QSALQSQQPPREQPLPPAPLA-MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962 Query: 1158 MPPPRKL-PQRSWAASIPTILTHSALNILLLPSP---TPGLVPGLAGSYLCSP 1206 +PPP L P S + P L ++ P +P PGL S P Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 1015 Score = 50.1 bits (118), Expect = 2e-05 Identities = 64/215 (29%), Positives = 85/215 (39%), Gaps = 30/215 (13%) Query: 999 QLQPPPQQQPFPKQPGTSGAYP----LTSP-PTSYHSTVNQSPSMMHTQSPGNLHAASSP 1053 Q QPP Q P P S A P L +P PT + V S +Q+P A ++P Sbjct: 735 QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 794 Query: 1054 --------SGALRAPSPASFVPTPPPSSH-------GISIGPGA-SFASP--HGTLDPSS 1095 + AL P S P P PS H G + P A S A P HG P Sbjct: 795 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ-GPPG 853 Query: 1096 PYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP 1155 P+++ +G PG PQ G P A G +P SP H+ +SQ+ Sbjct: 854 PHSL--QAGPLLQHPGPPQPFGLPPQASQ-GQAPLGT---SPAAAYPHTSLQLPASQSAL 907 Query: 1156 TNMPPPRKLPQRSWAASIPTILTHSALNILLLPSP 1190 + PPR+ P ++P I I LP+P Sbjct: 908 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 942 Score = 38.9 bits (89), Expect = 0.036 Identities = 39/142 (27%), Positives = 48/142 (33%), Gaps = 23/142 (16%) Query: 1000 LQPPPQQQPFPKQPGTSGAY---------PLTSPPTSYHSTVNQSPSMMHTQSPGNLHAA 1050 LQ PQ QP P P P + PPT H Q P H PG Sbjct: 988 LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI 1047 Query: 1051 SSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHG---TLDPSSPYTMVSPSGRAG 1107 + P+ PS ++ PP+ G S P S A+ G S P V A Sbjct: 1048 TPPT----CPSTST-----PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEAL 1098 Query: 1108 NWPGSPQVSGPSPAARMPGMSP 1129 + P+ P P R P P Sbjct: 1099 DDAEEPE--SPPPPPRSPSPEP 1118 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 52.0 bits (123), Expect = 4e-06 Identities = 70/241 (29%), Positives = 96/241 (39%), Gaps = 32/241 (13%) Query: 983 NPPSPIGGDMMDSLISQLQPP-PQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHT 1041 +PPS G + S + PP PQ+ P G+ P + PP V +P + + Sbjct: 142 SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPP-----VPSTPRPIQS 196 Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPP--SSHGISIGPGASFASPHGTLDPSSPYTM 1099 SP N + P G R PSP PTPPP + G ++G G+ SP + P S Sbjct: 197 -SPHNRGSPPVPGGP-RQPSPG---PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP 251 Query: 1100 VSPS-GRA--GNWPGSPQVSGPSPAARMPGMSPANPSLHSP-VPDASHSPRAGTSSQTMP 1155 + P+ RA P P G P+ + P P + P VP +PR SSQ Sbjct: 252 LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS---TPRPSASSQA-- 306 Query: 1156 TNMPPPRKLPQRSWAASIPTILTHS-------ALNILLLPSPTPGLVPGLAGSYLCSPLE 1208 PPP P R +P + + N+ L S P PG +G P E Sbjct: 307 ---PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363 Query: 1209 R 1209 R Sbjct: 364 R 364 Score = 47.0 bits (110), Expect = 1e-04 Identities = 51/192 (26%), Positives = 71/192 (36%), Gaps = 30/192 (15%) Query: 989 GGDMMDSLISQLQPPPQQQPFPKQPGTS--GAYPLTSPPT----SYHSTVNQSPSMMHTQ 1042 GG + S +S P + P P P + P PP S H P + + Sbjct: 232 GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK 291 Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFAS------PHGTLDPSSP 1096 P + + PS + +AP P PPPS G P +S + P L SS Sbjct: 292 PP--VPSTPRPSASSQAPPPP-----PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS 344 Query: 1097 YTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPT 1156 + GR+G P P P P PG S P+P R G++S+ +P Sbjct: 345 TPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS-------GPLPPPPPVSRNGSTSRALPA 397 Query: 1157 NMPPPRKLPQRS 1168 +LP RS Sbjct: 398 T----PQLPSRS 405 Score = 45.8 bits (107), Expect = 3e-04 Identities = 50/183 (27%), Positives = 62/183 (33%), Gaps = 29/183 (15%) Query: 976 RSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQ-----PFPKQPGTSGAYPLTSPPTSYHS 1030 R++++ PP P G+ + PPP Q P +P S P PP S Sbjct: 258 RALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS--- 314 Query: 1031 TVNQSPSMMHTQSPGNLHAASSP-------SGALRAPSPASFVPTPPPSSHGISIGPGAS 1083 P + S GN P S PSP P PPP S P Sbjct: 315 --RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE----RPPPP 368 Query: 1084 FASPHGTLDPSSPYTMVSPSGRAGN-WPGSPQ------VSGPSPAARMPGMSPANPSLHS 1136 P G P P VS +G P +PQ V P R P + P PS + Sbjct: 369 VRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR-PPLPPDRPSAGA 427 Query: 1137 PVP 1139 P P Sbjct: 428 PPP 430 Score = 40.4 bits (93), Expect = 0.013 Identities = 37/134 (27%), Positives = 47/134 (35%), Gaps = 19/134 (14%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPK---QPGTSGAYPLTSPPTSYHSTVNQSPSMMH 1040 PP P G L PPP ++P P PG SG P P + ST P+ Sbjct: 346 PPLPSPGRS-----GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ 400 Query: 1041 TQSPGNLHAA-SSPSGALRAPSPASFVPTPPPSSHGISIG----------PGASFASPHG 1089 S + + S P L P++ P PPP S I G + P Sbjct: 401 LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPIS 460 Query: 1090 TLDPSSPYTMVSPS 1103 L P PY + S Sbjct: 461 DLPPPEPYVQTTKS 474 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 52.0 bits (123), Expect = 4e-06 Identities = 70/241 (29%), Positives = 96/241 (39%), Gaps = 32/241 (13%) Query: 983 NPPSPIGGDMMDSLISQLQPP-PQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHT 1041 +PPS G + S + PP PQ+ P G+ P + PP V +P + + Sbjct: 142 SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPP-----VPSTPRPIQS 196 Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPP--SSHGISIGPGASFASPHGTLDPSSPYTM 1099 SP N + P G R PSP PTPPP + G ++G G+ SP + P S Sbjct: 197 -SPHNRGSPPVPGGP-RQPSPG---PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP 251 Query: 1100 VSPS-GRA--GNWPGSPQVSGPSPAARMPGMSPANPSLHSP-VPDASHSPRAGTSSQTMP 1155 + P+ RA P P G P+ + P P + P VP +PR SSQ Sbjct: 252 LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS---TPRPSASSQA-- 306 Query: 1156 TNMPPPRKLPQRSWAASIPTILTHS-------ALNILLLPSPTPGLVPGLAGSYLCSPLE 1208 PPP P R +P + + N+ L S P PG +G P E Sbjct: 307 ---PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363 Query: 1209 R 1209 R Sbjct: 364 R 364 Score = 47.0 bits (110), Expect = 1e-04 Identities = 51/192 (26%), Positives = 71/192 (36%), Gaps = 30/192 (15%) Query: 989 GGDMMDSLISQLQPPPQQQPFPKQPGTS--GAYPLTSPPT----SYHSTVNQSPSMMHTQ 1042 GG + S +S P + P P P + P PP S H P + + Sbjct: 232 GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK 291 Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFAS------PHGTLDPSSP 1096 P + + PS + +AP P PPPS G P +S + P L SS Sbjct: 292 PP--VPSTPRPSASSQAPPPP-----PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS 344 Query: 1097 YTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPT 1156 + GR+G P P P P PG S P+P R G++S+ +P Sbjct: 345 TPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS-------GPLPPPPPVSRNGSTSRALPA 397 Query: 1157 NMPPPRKLPQRS 1168 +LP RS Sbjct: 398 T----PQLPSRS 405 Score = 45.8 bits (107), Expect = 3e-04 Identities = 50/183 (27%), Positives = 62/183 (33%), Gaps = 29/183 (15%) Query: 976 RSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQ-----PFPKQPGTSGAYPLTSPPTSYHS 1030 R++++ PP P G+ + PPP Q P +P S P PP S Sbjct: 258 RALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS--- 314 Query: 1031 TVNQSPSMMHTQSPGNLHAASSP-------SGALRAPSPASFVPTPPPSSHGISIGPGAS 1083 P + S GN P S PSP P PPP S P Sbjct: 315 --RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE----RPPPP 368 Query: 1084 FASPHGTLDPSSPYTMVSPSGRAGN-WPGSPQ------VSGPSPAARMPGMSPANPSLHS 1136 P G P P VS +G P +PQ V P R P + P PS + Sbjct: 369 VRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR-PPLPPDRPSAGA 427 Query: 1137 PVP 1139 P P Sbjct: 428 PPP 430 Score = 40.4 bits (93), Expect = 0.013 Identities = 37/134 (27%), Positives = 47/134 (35%), Gaps = 19/134 (14%) Query: 984 PPSPIGGDMMDSLISQLQPPPQQQPFPK---QPGTSGAYPLTSPPTSYHSTVNQSPSMMH 1040 PP P G L PPP ++P P PG SG P P + ST P+ Sbjct: 346 PPLPSPGRS-----GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ 400 Query: 1041 TQSPGNLHAA-SSPSGALRAPSPASFVPTPPPSSHGISIG----------PGASFASPHG 1089 S + + S P L P++ P PPP S I G + P Sbjct: 401 LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPIS 460 Query: 1090 TLDPSSPYTMVSPS 1103 L P PY + S Sbjct: 461 DLPPPEPYVQTTKS 474 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 52.0 bits (123), Expect = 4e-06 Identities = 57/211 (27%), Positives = 81/211 (38%), Gaps = 20/211 (9%) Query: 972 DARRRSVNEDDNPPSPIGGDMMDSLI---SQLQPPPQQQPFPKQPGTSGAYPLTSPPTSY 1028 +A R S ++ P SP+ + S S L PPP++ P P +S PL P S Sbjct: 463 EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP 522 Query: 1029 HSTVNQSPSMMHTQSPGNLHAASSP--SGALRAPSPASFVPTPPPSSHGISIGPGASFAS 1086 SP++ SP + SP + +P P +PPP + +S P S S Sbjct: 523 PEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582 Query: 1087 PHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASH-SP 1145 P P SP P + +P P P P S SP P+AS SP Sbjct: 583 PPPEESPMSP-----PPEASRLFP---------PFEESPLSPPPEESPLSPPPEASRLSP 628 Query: 1146 RAGTSSQTMPTNMPPPRKLPQRSWAASIPTI 1176 S + P P P+ S + +P + Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVV 659 Score = 45.1 bits (105), Expect = 5e-04 Identities = 72/278 (25%), Positives = 94/278 (33%), Gaps = 69/278 (24%) Query: 983 NPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042 +PP + ++S+L PPP++ P P S P + PP + S ++ P T Sbjct: 645 SPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEES---PTSPPPEA--SRLSPPPEDSPTS 699 Query: 1043 SPGNLHAASSP--SGALRAP---SPASFVPTPP---PSSHGISIGPGASFASPHGTLDPS 1094 P AS P + P SP +P P P S G + P PH + P Sbjct: 700 PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE--EPHLSPRPE 757 Query: 1095 SPYTMVSPSGRAGNWPGSPQVSGP-----------SPAARMPGMSPANPSLH-------- 1135 P+ +SP + SPQ P SP A P +SP LH Sbjct: 758 EPH--LSPQAEEPHL--SPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813 Query: 1136 -----------SPVPDASH----------SPRAGTSSQTMPTNMPP----PRKLPQRSWA 1170 SP P+ SH SPR S + PP P K P+ Sbjct: 814 HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQ 873 Query: 1171 ASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLE 1208 P L L P P L P L L P E Sbjct: 874 CPAPEELP------LFPPPGEPSLSPLLGEPALSEPGE 905 Score = 41.6 bits (96), Expect = 0.006 Identities = 60/220 (27%), Positives = 78/220 (35%), Gaps = 25/220 (11%) Query: 998 SQLQPPPQQQPFPKQPGTS------GAYPLTSPPTSYHST--VNQSP-SMMHTQSPGNLH 1048 S L PPP++ P P S P + P + H + + +SP S +SP + Sbjct: 447 SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506 Query: 1049 AASSPSGALRAP--SPASFVPTPPPSSHGISIGPGASFASP---HGTLDPSSPYTMVSPS 1103 SSP L SP P P +S P AS SP L P SP Sbjct: 507 PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP 566 Query: 1104 GRAGNWPGSPQVSGPSPAARMPGMSPA----------NPSLHSPVPDASH-SPRAGTSSQ 1152 A P+ S SP MSP S SP P+ S SP S Sbjct: 567 PEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626 Query: 1153 TMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192 + P P P+ S + P + S L ++ SP P Sbjct: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPP 666 Score = 41.6 bits (96), Expect = 0.006 Identities = 50/186 (26%), Positives = 67/186 (36%), Gaps = 17/186 (9%) Query: 998 SQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASS-PSGA 1056 S L PPP++ P P S P PP S ++ P P + S P + Sbjct: 606 SPLSPPPEESPLSPPPEASRLSP---PPED--SPMSPPPEESPMSPPPEVSRLSPLPVVS 660 Query: 1057 LRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVS 1116 +P P +PPP S P AS SP P+SP SP A P +S Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP---ASPPPEDSLMS 717 Query: 1117 GP------SPAARMPGMSPANPSLH-SPVPDASH-SPRAGTSSQTMPTNMPPPRKLPQRS 1168 P P P + P + H SP P+ H SPR + P P+ Sbjct: 718 LPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEP 777 Query: 1169 WAASIP 1174 ++P Sbjct: 778 CLCAVP 783 Score = 38.5 bits (88), Expect = 0.048 Identities = 54/199 (27%), Positives = 73/199 (36%), Gaps = 32/199 (16%) Query: 1010 PKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTP 1069 P QPG G+ P + PT + + +P+ + T + G L PA VP P Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPT-TPAGLSTSADGFLKP------------PAGSVPGP 2153 Query: 1070 PPSSHGISIGPGASFASPHGTLDPSSPYTMVS--PSGRAGNWPGSPQVSGPSPAARMPGM 1127 PG F L P P + S P G A +P P+ +P P Sbjct: 2154 D--------SPGELFLK----LPPQVPAQVPSQDPFGLAPAYPLEPRFP-TAPPTYPPYP 2200 Query: 1128 SPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLL 1187 SP P+ AS P AG + T PR P P +L+ L + Sbjct: 2201 SPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRC---PSLDNLAV 2257 Query: 1188 PSPTPGLVPGLAGSYLCSP 1206 P +PG+ G A L SP Sbjct: 2258 PE-SPGVGGGKASEPLLSP 2275 Score = 38.5 bits (88), Expect = 0.048 Identities = 53/195 (27%), Positives = 65/195 (33%), Gaps = 46/195 (23%) Query: 1001 QPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSP-SMMHTQSP-------GNLHAASS 1052 QPP +P P P + A P S P+ S V SP S +QSP S Sbjct: 2380 QPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP 2439 Query: 1053 PSGALRAPSPASFVPTPPPS----------------------------SHGISIGPGASF 1084 + ++P P S P+ P S S G P A Sbjct: 2440 VTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALP 2499 Query: 1085 ASPHGTLDPSSPYTMVSPSGRAGNWPGSPQ----VSGPSPAARMPGMSPANPSLHSPVPD 1140 A P G L PSG+ N+ SP V PSP + PSL PVP Sbjct: 2500 AGPAGELHAK------VPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQ 2553 Query: 1141 ASHSPRAGTSSQTMP 1155 P G +S P Sbjct: 2554 PGLPPPHGINSHFGP 2568 Score = 37.4 bits (85), Expect = 0.11 Identities = 44/163 (26%), Positives = 57/163 (34%), Gaps = 37/163 (22%) Query: 1000 LQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059 L PPP++ P P S TSPP P + + Sbjct: 440 LLPPPEESPLSPPPEESP----TSPP---------------------------PEASRLS 468 Query: 1060 PSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGS-PQVSGP 1118 P P +P P + +S S SP P SP SP P S P+ S P Sbjct: 469 PPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPP 528 Query: 1119 SPAARMPGMSPANPS-LHSPVPDASHSPRAGTSSQTMPTNMPP 1160 SPA P P S L P ++ SP + +PT+ PP Sbjct: 529 SPALETPLSPPPEASPLSPPFEESPLSP----PPEELPTSPPP 567 Score = 35.8 bits (81), Expect = 0.31 Identities = 36/140 (25%), Positives = 50/140 (35%), Gaps = 13/140 (9%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTS-----PPTSYHS------TVNQSPSMMHTQSPGNLHAA 1050 P P + FP+ G P PP +S T+ + S +T + GN H + Sbjct: 2531 PSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPS 2590 Query: 1051 SSPSGALRAPSPASF--VPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGN 1108 SP G + S+ P PPS G+ HG S + V G Sbjct: 2591 GSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGT 2650 Query: 1109 WPGSPQVSGPSPAARMPGMS 1128 GS + P + PGMS Sbjct: 2651 GMGSSLATAELPGTQDPGMS 2670 Score = 33.1 bits (74), Expect = 2.0 Identities = 39/152 (25%), Positives = 55/152 (36%), Gaps = 21/152 (13%) Query: 992 MMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG--NLHA 1049 +M + Q Q Q P+ ++PGT TSP Q Q+ L A Sbjct: 4226 LMQRQLQQSQAVRQTPPY-QEPGTQ-----TSPLQGLLGCQPQLGGFPGPQTGPLQELGA 4279 Query: 1050 ASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGR---- 1105 P G R P+P + T P +GP P +P P + SPS + Sbjct: 4280 GPRPQGPPRLPAPPGALSTGPV------LGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTE 4333 Query: 1106 ---AGNWPGSPQVSGPSPAARMPGMSPANPSL 1134 PG+P+ GP+ +SPA L Sbjct: 4334 AQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQL 4365 Score = 31.6 bits (70), Expect = 5.8 Identities = 45/177 (25%), Positives = 66/177 (37%), Gaps = 26/177 (14%) Query: 996 LISQLQPPPQQQPFPKQPGTSGAYP----LTSPPTSYHSTVNQSPS-------MMHTQSP 1044 L+S P + FP+ P +G P P +SP P Sbjct: 4806 LLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLP 4865 Query: 1045 G-NLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPS 1103 G L + L+ SPA PT ++ +S ++P +PS P + ++PS Sbjct: 4866 GYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPE-EPSPPPSPLAPS 4924 Query: 1104 GRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPP 1160 P SP P +P A P + SP+P AS SP S++ P PP Sbjct: 4925 ------PASPPTE---PLVELPTEPLAEPPVPSPLPLAS-SPE---SARPKPRARPP 4968 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 51.6 bits (122), Expect = 5e-06 Identities = 51/184 (27%), Positives = 70/184 (38%), Gaps = 26/184 (14%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTS-------PPTSYHSTVNQSPSMMHTQSPGNLHAASSPS 1054 PPP P P+ P ++ P S PT YH+ + S M PG A P Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPG----APPPH 216 Query: 1055 GALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYT--MVSPSGRAGNWPGS 1112 L + PP G G +S P+G P T VS SG +G P Sbjct: 217 PQLYPGGTGGVLSGPPMGPKG--GGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK 274 Query: 1113 P--------QVSGPSPAARMPGMSP--ANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPR 1162 P + P A P ++P P P+ +AS SP G +Q +P ++P P Sbjct: 275 PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP-PGLGAQPLPGHLPSPH 333 Query: 1163 KLPQ 1166 + Q Sbjct: 334 AMGQ 337 Score = 41.2 bits (95), Expect = 0.007 Identities = 56/209 (26%), Positives = 76/209 (36%), Gaps = 31/209 (14%) Query: 984 PPSPIGGDMMDSLIS----QLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMM 1039 P P GG S+ + PPP G SGA P T PPT+ Sbjct: 232 PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPP-TKPPTT------------ 278 Query: 1040 HTQSPGNLHAASSPSGALRAPSPASFVPTPP---PSSHGISIGPGASFASPHGTLDPSSP 1096 GNL +A P+ P +P PP P ++ + PG G L SP Sbjct: 279 -PVGGGNLPSAPPPA---NFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHL--PSP 332 Query: 1097 YTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPA-NPSLHSPVPDASHSPRAGTSSQTMP 1155 + M G P PSP + P S A P + P +S S A +SS + Sbjct: 333 HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSS 392 Query: 1156 TN----MPPPRKLPQRSWAASIPTILTHS 1180 ++ P + LP + PT L+ S Sbjct: 393 SSSASPFPASQALPSYPHSFPPPTSLSVS 421 Score = 38.1 bits (87), Expect = 0.062 Identities = 49/199 (24%), Positives = 64/199 (32%), Gaps = 39/199 (19%) Query: 1004 PQQQPFPKQPGTSGAYPLTSPPTSYHS---------TVNQSPSMMHTQSPGN-------- 1046 P P P Q YP PT S TV SP+ T SP Sbjct: 584 PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA 643 Query: 1047 ----LHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSP 1102 + ++P G + SP SF PP G S G GT P SP Sbjct: 644 PSPGAYKTATPPG-YKPGSPPSFRTGTPPGYRGTSPPAGP------GTFKPGSPTV---- 692 Query: 1103 SGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPR 1162 PG +GPS +P PA P+ P+ +T + +PP R Sbjct: 693 ------GPGPLPPAGPSGLPSLP-PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPAR 745 Query: 1163 KLPQRSWAASIPTILTHSA 1181 +P+ + SA Sbjct: 746 SPSPPPKVVDVPSHASQSA 764 Score = 38.1 bits (87), Expect = 0.062 Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 32/146 (21%) Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062 PP P+ K+ + GAY +PP SP T +P S P+G P Sbjct: 633 PPGPPPYGKRAPSPGAYKTATPP----GYKPGSPPSFRTGTPPGYRGTSPPAG------P 682 Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAA 1122 +F P P ++GP G L P+ P + S P + SGP +A Sbjct: 683 GTFKPGSP------TVGP--------GPLPPAGPSGLPSLPP-----PPAAPASGPPLSA 723 Query: 1123 RMPGMSPAN--PSLHSPVPDA-SHSP 1145 PA + SPVP A S SP Sbjct: 724 TQIKQEPAEEYETPESPVPPARSPSP 749 Score = 37.0 bits (84), Expect = 0.14 Identities = 48/186 (25%), Positives = 69/186 (37%), Gaps = 18/186 (9%) Query: 1001 QPPPQQQPFPKQPGTSGAYPLTSPP-TSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059 Q PP P+ + S A+P PP T ST + S H + Sbjct: 440 QGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499 Query: 1060 PSPASFVPTPPPSSHGISIGPGASFASP--HGTLDPSSPYTMVSPSGRAGNWPGSPQVSG 1117 PPP PGA F P G+ + PY M G +P P Sbjct: 500 QQQHHGNSGPPP--------PGA-FPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP-AHL 549 Query: 1118 PSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRS--WAASIPT 1175 P P +++ S A P + P +S + + TS + P + P P + PQ + +PT Sbjct: 550 PPPHSQV-SYSQAGP--NGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPT 606 Query: 1176 ILTHSA 1181 + T SA Sbjct: 607 VTTSSA 612 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 51.6 bits (122), Expect = 5e-06 Identities = 51/184 (27%), Positives = 70/184 (38%), Gaps = 26/184 (14%) Query: 1002 PPPQQQPFPKQPGTSGAYPLTS-------PPTSYHSTVNQSPSMMHTQSPGNLHAASSPS 1054 PPP P P+ P ++ P S PT YH+ + S M PG A P Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPG----APPPH 216 Query: 1055 GALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYT--MVSPSGRAGNWPGS 1112 L + PP G G +S P+G P T VS SG +G P Sbjct: 217 PQLYPGGTGGVLSGPPMGPKG--GGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK 274 Query: 1113 P--------QVSGPSPAARMPGMSP--ANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPR 1162 P + P A P ++P P P+ +AS SP G +Q +P ++P P Sbjct: 275 PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP-PGLGAQPLPGHLPSPH 333 Query: 1163 KLPQ 1166 + Q Sbjct: 334 AMGQ 337 Score = 41.2 bits (95), Expect = 0.007 Identities = 56/209 (26%), Positives = 76/209 (36%), Gaps = 31/209 (14%) Query: 984 PPSPIGGDMMDSLIS----QLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMM 1039 P P GG S+ + PPP G SGA P T PPT+ Sbjct: 232 PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPP-TKPPTT------------ 278 Query: 1040 HTQSPGNLHAASSPSGALRAPSPASFVPTPP---PSSHGISIGPGASFASPHGTLDPSSP 1096 GNL +A P+ P +P PP P ++ + PG G L SP Sbjct: 279 -PVGGGNLPSAPPPA---NFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHL--PSP 332 Query: 1097 YTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPA-NPSLHSPVPDASHSPRAGTSSQTMP 1155 + M G P PSP + P S A P + P +S S A +SS + Sbjct: 333 HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSS 392 Query: 1156 TN----MPPPRKLPQRSWAASIPTILTHS 1180 ++ P + LP + PT L+ S Sbjct: 393 SSSASPFPASQALPSYPHSFPPPTSLSVS 421 Score = 38.1 bits (87), Expect = 0.062 Identities = 49/199 (24%), Positives = 64/199 (32%), Gaps = 39/199 (19%) Query: 1004 PQQQPFPKQPGTSGAYPLTSPPTSYHS---------TVNQSPSMMHTQSPGN-------- 1046 P P P Q YP PT S TV SP+ T SP Sbjct: 584 PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA 643 Query: 1047 ----LHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSP 1102 + ++P G + SP SF PP G S G GT P SP Sbjct: 644 PSPGAYKTATPPG-YKPGSPPSFRTGTPPGYRGTSPPAGP------GTFKPGSPTV---- 692 Query: 1103 SGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPR 1162 PG +GPS +P PA P+ P+ +T + +PP R Sbjct: 693 ------GPGPLPPAGPSGLPSLP-PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPAR 745 Query: 1163 KLPQRSWAASIPTILTHSA 1181 +P+ + SA Sbjct: 746 SPSPPPKVVDVPSHASQSA 764 Score = 38.1 bits (87), Expect = 0.062 Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 32/146 (21%) Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062 PP P+ K+ + GAY +PP SP T +P S P+G P Sbjct: 633 PPGPPPYGKRAPSPGAYKTATPP----GYKPGSPPSFRTGTPPGYRGTSPPAG------P 682 Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAA 1122 +F P P ++GP G L P+ P + S P + SGP +A Sbjct: 683 GTFKPGSP------TVGP--------GPLPPAGPSGLPSLPP-----PPAAPASGPPLSA 723 Query: 1123 RMPGMSPAN--PSLHSPVPDA-SHSP 1145 PA + SPVP A S SP Sbjct: 724 TQIKQEPAEEYETPESPVPPARSPSP 749 Score = 37.0 bits (84), Expect = 0.14 Identities = 48/186 (25%), Positives = 69/186 (37%), Gaps = 18/186 (9%) Query: 1001 QPPPQQQPFPKQPGTSGAYPLTSPP-TSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059 Q PP P+ + S A+P PP T ST + S H + Sbjct: 440 QGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499 Query: 1060 PSPASFVPTPPPSSHGISIGPGASFASP--HGTLDPSSPYTMVSPSGRAGNWPGSPQVSG 1117 PPP PGA F P G+ + PY M G +P P Sbjct: 500 QQQHHGNSGPPP--------PGA-FPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP-AHL 549 Query: 1118 PSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRS--WAASIPT 1175 P P +++ S A P + P +S + + TS + P + P P + PQ + +PT Sbjct: 550 PPPHSQV-SYSQAGP--NGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPT 606 Query: 1176 ILTHSA 1181 + T SA Sbjct: 607 VTTSSA 612 >gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] Length = 727 Score = 50.8 bits (120), Expect = 9e-06 Identities = 51/192 (26%), Positives = 79/192 (41%), Gaps = 19/192 (9%) Query: 1023 SPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP-ASFVPTPPPSSHGISIGPG 1081 +P + +T P+ + + AAS P A + AS T P SS S P Sbjct: 305 APVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADSPRPQ 364 Query: 1082 ASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDA 1141 AS SP + + S A + S + P+P R+ + PS++ PVP + Sbjct: 365 ASSYSP----------AVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPAS 414 Query: 1142 SHSPRAGTS-SQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAG 1200 ++SP G + S T T P P P + A + + T++ PSP P P A Sbjct: 415 TYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYT-------PSPAPAYTPSPAP 467 Query: 1201 SYLCSPLERFLG 1212 +Y +P + G Sbjct: 468 NYNPAPSVAYSG 479 Score = 33.5 bits (75), Expect = 1.5 Identities = 53/238 (22%), Positives = 79/238 (33%), Gaps = 50/238 (21%) Query: 991 DMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG----N 1046 D SL++ P P+ + P PGT P SP S S + S+ PG + Sbjct: 112 DTNGSLVAP-SPSPEARASPGTPGTPELRPTFSPAFSRPSAFS---SLAEASDPGPPRAS 167 Query: 1047 LHAASSPSGALRAPSPASFVPTPPPSSHGISIG--------------------------- 1079 L A +SP GA P + + P + IG Sbjct: 168 LRAKTSPEGARDLLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGL 227 Query: 1080 PGASFASPHGTLDPSSP-YTMV-----SPSGRAGNW---PGSPQVSGPSPAARMPG---- 1126 PG S +D +SP Y V P A W + Q A+M G Sbjct: 228 PGGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFM 287 Query: 1127 MSPANPSLHSPVPDASHSPRAGTSSQT--MPTNMPPPRKLPQRSWAASIPTILTHSAL 1182 P +L H+P + + T +P + PP + + + T H+A+ Sbjct: 288 QDPDEEALRRSSTPIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAI 345 Score = 33.1 bits (74), Expect = 2.0 Identities = 43/184 (23%), Positives = 71/184 (38%), Gaps = 20/184 (10%) Query: 955 PAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPG 1014 P P ++ S+ A S +E P+P + + I +P QP Sbjct: 361 PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASI---------RPSVYQPV 411 Query: 1015 TSGAYPLTSPPTSYHST-VNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSS 1073 + Y SP +Y T SP+ +T SP + S +P+PA + P+P P Sbjct: 412 PASTYS-PSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPA-YTPSPAP-- 467 Query: 1074 HGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNW-PG--SPQVSGPSPAARMPGMSPA 1130 + P S A G +P+S V+ + + PG + +S + P +PA Sbjct: 468 ---NYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPA 524 Query: 1131 NPSL 1134 P + Sbjct: 525 GPQV 528 >gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transferase 4 [Homo sapiens] Length = 1039 Score = 50.8 bits (120), Expect = 9e-06 Identities = 59/202 (29%), Positives = 75/202 (37%), Gaps = 32/202 (15%) Query: 968 DSNQDARRRS---VNEDDNPPSPIGGDMMDSLISQLQPPPQ---QQPFPKQPGTSGAYPL 1021 D + +RR+ +N DD G+++DSL PP+ Q P P P GA Sbjct: 416 DEEDEVQRRAFLFLNPDDFLDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGA--T 473 Query: 1022 TSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPG 1081 +PPT +P S A P RAP P V PPP + + PG Sbjct: 474 LAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPG 533 Query: 1082 ASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQV-SGPSPAARMPGMSPANPSLHSPVPD 1140 ASP +P+ RA WP P V P P R+ +P P P Sbjct: 534 QR-ASPR------------APAPRA-PWPPFPGVFLHPRPLPRVQLRAP-------PRPP 572 Query: 1141 ASHSPRAGTSSQTMPTNMPPPR 1162 H R G T P PP R Sbjct: 573 RPHGRRTGGPQATQP--RPPAR 592 >gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 490 Score = 50.4 bits (119), Expect = 1e-05 Identities = 54/211 (25%), Positives = 88/211 (41%), Gaps = 18/211 (8%) Query: 992 MMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAAS 1051 ++ L+S + PP P S ++SPP+ S ++ PS++ + Sbjct: 106 LVSPLLSGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSLL----------SG 155 Query: 1052 SPSGALRAPSPASFVPTPPPSSHGISIG---PGASFASPHGTLDPSSPYTMVSPSGRAGN 1108 PS PSP S VP+PP + G P + SP + PS P + S Sbjct: 156 VPSPPSDVPSPPSDVPSPPSDVPSLLSGVPSPPSDVPSPPSDV-PSPPSDVPLLSDVPSP 214 Query: 1109 WPGSPQVSG-PSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQR 1167 P +S PSP + +P + PSL S P + + P+++ PP +P Sbjct: 215 PSDVPLLSDVPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSPPSDISPPSDVP-- 272 Query: 1168 SWAASIPTILTHSALNILLLPSPTPGLVPGL 1198 S + +P++ + + +PSP P VP L Sbjct: 273 SLLSDVPSLPSDVPSLLSGVPSP-PSDVPSL 302 Score = 43.1 bits (100), Expect = 0.002 Identities = 49/189 (25%), Positives = 74/189 (39%), Gaps = 34/189 (17%) Query: 983 NPPSPIGGDMMDSLISQLQPPPQQQPFPKQ--PGTSGAYPLTSPPTSYHSTVNQSPSMMH 1040 +PPS + SL+S + PP P P P SG + SPP+ S + PS Sbjct: 294 SPPSDV-----PSLLSDVPSPPSDVPSPPSDIPLLSG---VPSPPSDVPSPPSDVPS--- 342 Query: 1041 TQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMV 1100 P ++ S L S VP+PP + + SPH L S Y++V Sbjct: 343 --PPSDVPLLSGVPSPLSDVPLLSGVPSPPSDVPSLLM-------SPHRLL--MSHYSLV 391 Query: 1101 SPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPP 1160 SP ++ PS + +P + PS S VP + ++P+ +P Sbjct: 392 SPH----------RLDVPSLLSDVPSLLSGVPSSPSGVPSLPSGVPILSGVPSLPSGVPS 441 Query: 1161 PRKLPQRSW 1169 P +P W Sbjct: 442 PSGVPITLW 450 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.134 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63,028,603 Number of Sequences: 37866 Number of extensions: 3421292 Number of successful extensions: 35631 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 157 Number of HSP's successfully gapped in prelim test: 1262 Number of HSP's that attempted gapping in prelim test: 24687 Number of HSP's gapped (non-prelim): 11345 length of query: 1454 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1339 effective length of database: 13,892,928 effective search space: 18602630592 effective search space used: 18602630592 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.