Guide to the Human Genome
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Search of human proteins with 28558973

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28558973 mediator complex subunit 14 [Homo sapiens]
         (1454 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28558973 mediator complex subunit 14 [Homo sapiens]               2929   0.0  
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    59   3e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    57   1e-07
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                56   2e-07
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                56   2e-07
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                56   2e-07
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         56   3e-07
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               56   3e-07
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    55   4e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   5e-07
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    55   5e-07
gi|116284392 mucin 2 precursor [Homo sapiens]                          54   1e-06
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                53   2e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is...    53   2e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   3e-06
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    52   3e-06
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    52   3e-06
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    52   3e-06
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...    52   3e-06
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          52   3e-06
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          52   3e-06
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          52   3e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    52   4e-06
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    52   4e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    52   4e-06
gi|55750053 atrophin-1 [Homo sapiens]                                  52   5e-06
gi|55750041 atrophin-1 [Homo sapiens]                                  52   5e-06
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              51   9e-06
gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transfera...    51   9e-06
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi...    50   1e-05

>gi|28558973 mediator complex subunit 14 [Homo sapiens]
          Length = 1454

 Score = 2929 bits (7592), Expect = 0.0
 Identities = 1454/1454 (100%), Positives = 1454/1454 (100%)

Query: 1    MAPVQLENHQLVPPGGGGGGSGGPPSAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLH 60
            MAPVQLENHQLVPPGGGGGGSGGPPSAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLH
Sbjct: 1    MAPVQLENHQLVPPGGGGGGSGGPPSAPAPPPPGAAVAAAAAAAASPGYRLSTLIEFLLH 60

Query: 61   RAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISS 120
            RAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISS
Sbjct: 61   RAYSELMVLTDLLPRKSDVERKIEIVQFASRTRQLFVRLLALVKWANNAGKVEKCAMISS 120

Query: 121  FLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPP 180
            FLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPP
Sbjct: 121  FLDQQAILFVDTADRLASLARDALVHARLPSFAIPYAIDVLTTGSYPRLPTCIRDKIIPP 180

Query: 181  DPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDD 240
            DPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDD
Sbjct: 181  DPITKIEKQATLHQLNQILRHRLVTTDLPPQLANLTVANGRVKFRVEGEFEATLTVMGDD 240

Query: 241  PDVPWRLLKLEILVEDKETGDGRALVHSMQISFIHQLVQSRLFADEKPLQDMYNCLHSFC 300
            PDVPWRLLKLEILVEDKETGDGRALVHSMQISFIHQLVQSRLFADEKPLQDMYNCLHSFC
Sbjct: 241  PDVPWRLLKLEILVEDKETGDGRALVHSMQISFIHQLVQSRLFADEKPLQDMYNCLHSFC 300

Query: 301  LSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIK 360
            LSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIK
Sbjct: 301  LSLQLEVLHSQTLMLIRERWGDLVQVERYHAGKCLSLSVWNQQVLGRKTGTASVHKVTIK 360

Query: 361  IDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAIL 420
            IDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAIL
Sbjct: 361  IDENDVSKPLQIFHDPPLPASDSKLVERAMKIDHLSIEKLLIDSVHARAHQKLQELKAIL 420

Query: 421  RGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEK 480
            RGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEK
Sbjct: 421  RGFNANENSSIETALPALVVPILEPCGNSECLHIFVDLHSGMFQLMLYGLDQATLDDMEK 480

Query: 481  SVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFI 540
            SVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFI
Sbjct: 481  SVNDDMKRIIPWIQQLKFWLGQQRCKQSIKHLPTISSETLQLSNYSTHPIGNLSKNKLFI 540

Query: 541  KLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPAMALLLQQFKENIQDLVF 600
            KLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPAMALLLQQFKENIQDLVF
Sbjct: 541  KLTRLPQYYIVVEMLEVPNKPTQLSYKYYFMSVNAADREDSPAMALLLQQFKENIQDLVF 600

Query: 601  RTKTGKQTRTNAKRKLSDDPCPVESKKTKRAGEMCAFNKVLAHFVAMCDTNMPFVGLRLE 660
            RTKTGKQTRTNAKRKLSDDPCPVESKKTKRAGEMCAFNKVLAHFVAMCDTNMPFVGLRLE
Sbjct: 601  RTKTGKQTRTNAKRKLSDDPCPVESKKTKRAGEMCAFNKVLAHFVAMCDTNMPFVGLRLE 660

Query: 661  LSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGITEETQKALDRSLLDCTFRLQGRNNRTW 720
            LSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGITEETQKALDRSLLDCTFRLQGRNNRTW
Sbjct: 661  LSNLEIPHQGVQVEGDGFSHAIRLLKIPPCKGITEETQKALDRSLLDCTFRLQGRNNRTW 720

Query: 721  VAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECV 780
            VAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECV
Sbjct: 721  VAELVFANCPLNGTSTREQGPSRHVYLTYENLLSEPVGGRKVVEMFLNDWNSIARLYECV 780

Query: 781  LEFARSLPDIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGP 840
            LEFARSLPDIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGP
Sbjct: 781  LEFARSLPDIPAHLNIFSEVRVYNYRKLILCYGTTKGSSISIQWNSIHQKFHISLGTVGP 840

Query: 841  NSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTA 900
            NSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTA
Sbjct: 841  NSGCSNCHNTILHQLQEMFNKTPNVVQLLQVLFDTQAPLNAINKLPTVPMLGLTQRTNTA 900

Query: 901  YQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLK 960
            YQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLK
Sbjct: 901  YQCFSILPQSSTHIRLAFRNMYCIDIYCRSRGVVAIRDGAYSLFDNSKLVEGFYPAPGLK 960

Query: 961  TFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP 1020
            TFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP
Sbjct: 961  TFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP 1020

Query: 1021 LTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGP 1080
            LTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGP
Sbjct: 1021 LTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGP 1080

Query: 1081 GASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPD 1140
            GASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPD
Sbjct: 1081 GASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPD 1140

Query: 1141 ASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAG 1200
            ASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAG
Sbjct: 1141 ASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAG 1200

Query: 1201 SYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQT 1260
            SYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQT
Sbjct: 1201 SYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQT 1260

Query: 1261 LQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIM 1320
            LQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIM
Sbjct: 1261 LQLKVTPENAGQWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIM 1320

Query: 1321 KLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEP 1380
            KLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEP
Sbjct: 1321 KLELFPDQATQLKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEP 1380

Query: 1381 VSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVR 1440
            VSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVR
Sbjct: 1381 VSIIVPIIYDMASGTTQQADIPRQQNSSVAAPMMVSNILKRFAEMNPPRQGECTIFAAVR 1440

Query: 1441 DLMANLTLPPGGRP 1454
            DLMANLTLPPGGRP
Sbjct: 1441 DLMANLTLPPGGRP 1454


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 73/242 (30%), Positives = 98/242 (40%), Gaps = 31/242 (12%)

Query: 973  ARRRSVNEDDNPPSPIGGDMMDSLISQL---QPPPQQQPFPKQPGTSGAYPLTSPPTSYH 1029
            ARR +       PSP       +  +++   +P P  +P   +P T G     S   S H
Sbjct: 151  ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSS-ASEH 206

Query: 1030 STVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHG 1089
            ST   SP+     S G         G L+ P+  S   +  P S     GP A   +P  
Sbjct: 207  STTEPSPAARRRPSAG---------GGLQRPASRSLSSSATPLSSPARSGPSAR-GTPRA 256

Query: 1090 TLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPS-LHSPVPDASHSPRAG 1148
               PS P     P G     P  PQV+ P   A  P + P + S L +P P A  SP A 
Sbjct: 257  PAHPSQP----KPKGLQALRP--PQVTPPRKDAA-PALGPLSSSPLATPSPSAPPSPSAP 309

Query: 1149 TSSQTMPTNMPPPRKLPQRSWAASIPTI-LTHSAL---NILLLPSPTPGLVPGLAGSYLC 1204
             S QT+P+  PP     Q + +   PT+  THS L    +  L +P P   P LA   L 
Sbjct: 310  PSLQTLPS--PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367

Query: 1205 SP 1206
            +P
Sbjct: 368  AP 369



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 52/215 (24%), Positives = 80/215 (37%), Gaps = 36/215 (16%)

Query: 985  PSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSP 1044
            P+ +   ++ +  S    PP Q PF   P +    P  +PP+    ++   P  +    P
Sbjct: 389  PNALAVHLLQAPFSPPPSPPVQAPF-SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 447

Query: 1045 GNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSG 1104
                          A  P S   TPPP +      P    A P     P +P  + +P  
Sbjct: 448  --------------ASPPMSPSATPPPQAPPPLAAPPLQLAKP----PPQAPPALATP-- 487

Query: 1105 RAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPV-PDASHSPRA----GTSSQTMPTNMP 1159
                    P  + PSP A  PG +P +PS   P+ P A+  P+A          +P + P
Sbjct: 488  --------PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539

Query: 1160 --PPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192
              P  + P+R       T ++   L + L P P P
Sbjct: 540  ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 60/220 (27%), Positives = 87/220 (39%), Gaps = 30/220 (13%)

Query: 1003 PPQQQPFPKQP----GTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGA-- 1056
            PPQ  P  K      G   + PL +P  S   + +  PS+    SP     A+ PS A  
Sbjct: 273  PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP----PATPPSQATT 328

Query: 1057 -LRAPS-----------PASFVPTPPPSSH-GISIGPGASFASPHGT--LDPSSPYTMVS 1101
             L +P+           P S + TPPP +   +++ P  +  SP  +  L P +  +  +
Sbjct: 329  SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 388

Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMP-- 1159
            P+  A +   +P    PSP  + P   PA+P +    P A+   +A  S    P  +P  
Sbjct: 389  PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS---PSATPPSQAPPSLAAPPLQVPPS 445

Query: 1160 PPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLA 1199
            PP   P    A   P      A   L L  P P   P LA
Sbjct: 446  PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 485



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 108/442 (24%), Positives = 145/442 (32%), Gaps = 57/442 (12%)

Query: 1000 LQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059
            L P P   P P  P T  A  +          V + P     +  G +  A+ P  A RA
Sbjct: 25   LTPRPPGSPRPPPPVTPAALRVLGAA----GAVGRKPL---AERAGGIGGATIPESAPRA 77

Query: 1060 -PSPASFVPTPPPSSHGISIGPGASFASPHGTLDP--SSPYTMVSPSGRAGNWPGSPQVS 1116
             P+  S    PP S  G    P A   SP     P  +S  T   P G+ G    + +  
Sbjct: 78   GPTRTS---RPPASGRG-ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133

Query: 1117 GPSPAARMPGMSP---------ANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPR-KLPQ 1166
                A   P  S          + P+  +P P  +   RA  +   +P   P  R + P 
Sbjct: 134  ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193

Query: 1167 RSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMR--------- 1217
                 S+ +   HS       PSP     P  AG  L  P  R L S             
Sbjct: 194  EGPRKSVSSASEHSTTE----PSPAARRRPS-AGGGLQRPASRSLSSSATPLSSPARSGP 248

Query: 1218 ------RHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAG 1271
                  R      Q +   L     P V   + DA     AL P ++  L          
Sbjct: 249  SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP---ALGPLSSSPLATPSPSAPPS 305

Query: 1272 QWKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQ 1331
               P  LQ L     +  A PP +A T +    L    TH       +  L   P QA  
Sbjct: 306  PSAPPSLQTLP----SPPATPPSQATTSLGSPTLQA--THSFLPSPPLSPLATPPPQAPP 359

Query: 1332 -LKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYD 1390
             L          PP++PP++P  TP+    + +   L L    S PP  PV    P    
Sbjct: 360  ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQ--APFSPP 416

Query: 1391 MASGTTQQADIPRQQNSSVAAP 1412
             +   +  A  P Q   S+AAP
Sbjct: 417  ASPPVSPSATPPSQAPPSLAAP 438



 Score = 38.5 bits (88), Expect = 0.048
 Identities = 48/174 (27%), Positives = 64/174 (36%), Gaps = 12/174 (6%)

Query: 983  NPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042
            +PP+   G    S  + L   P   P P+ P    A  L  PP+   S   Q+P    T 
Sbjct: 494  SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT- 552

Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSP-----Y 1097
             PG   + S P   L A +P    P PPPS    S   G   A  H +   S+P     Y
Sbjct: 553  -PGPDTSVSGPRLTL-ALAPG---PPPPPSRSPSSTLSGPDLAG-HSSSATSTPEELRGY 606

Query: 1098 TMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSS 1151
                  G A + P   +++   PAA   G +P      +P       P  G  S
Sbjct: 607  DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 660



 Score = 37.7 bits (86), Expect = 0.081
 Identities = 54/224 (24%), Positives = 72/224 (32%), Gaps = 43/224 (19%)

Query: 1002 PPPQQQPF---------PKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAAS- 1051
            PPPQ  P          P  P +        PPT    T    P +    +PG     S 
Sbjct: 519  PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578

Query: 1052 SPSGALRAPSPA---SFVPTPPPSSHGISIGP-GASFASPHGTLD------------PSS 1095
            SPS  L  P  A   S   + P    G   GP G + ASP    +            P+ 
Sbjct: 579  SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 638

Query: 1096 PYTMVSPSGRAGNWPGSP------------QVSGPSPAARMPGMSPANPSLHSPVPDASH 1143
            P       G    WP +             +  GP  A   PG     PS  +    A+ 
Sbjct: 639  PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 698

Query: 1144 SPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLL 1187
               AG SS++     P   +L +    A   +++ H     LLL
Sbjct: 699  GAGAGASSRS-----PKQARLGELPLGALQASVVQHLLSRTLLL 737


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 68/234 (29%), Positives = 92/234 (39%), Gaps = 28/234 (11%)

Query: 984  PPSPIGGDMMDSLISQLQP-----PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSM 1038
            PPSP G     S ++ L P     PP++ P P        +P   P T       Q+P++
Sbjct: 858  PPSPKGAPT-PSAVTPLSPKGVTLPPKETPTPSVVNLP--FPKEGPATP---APKQAPAL 911

Query: 1039 -MHTQSPGNLHAASSPSGALRAPSPASFVPTPP----PSSHGISIGPGASFA-SPHGTLD 1092
             M + SP    A  +P G   +PSP    PTPP    PS  G    P   +A +P     
Sbjct: 912  SMTSSSPKKARATPAPKGIPASPSPKG-APTPPAATPPSPKGGPATPSPKWAPTPPAATP 970

Query: 1093 PSSPYTMVSPSGRAGNWPGSPQVSGPSP----AARMPGMSPANPSLHSPVPDASHSPRAG 1148
            PS      +PS +    P  P  + PSP    A   P  +P  P++  P P  S +    
Sbjct: 971  PSPKGGPATPSPKGA--PTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028

Query: 1149 TSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPG-LVPGLAGS 1201
                + P    PP   P+ S AA+ P            LPSP  G   P L G+
Sbjct: 1029 PKGASTPPAATPPS--PKGSPAAT-PLPKGAPTTPAATLPSPKGGPATPSLKGA 1079



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 74/254 (29%), Positives = 91/254 (35%), Gaps = 45/254 (17%)

Query: 985  PSPIGGDMMDSLISQLQPPPQQQPFPK----QPGTSGAY--PLTSPP-------TSYHST 1031
            PSP GG    SL     PP    P PK     P   GA   P  +PP       T  H  
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124

Query: 1032 VNQSPSMMHTQSPGNLHAASSPSGA-----LRAPSPASFVPTPPPSSHGISIGPGASFAS 1086
               +P+       G L A   P GA        PSP   + TPPP   G    P A+  S
Sbjct: 1125 APTTPAATPPSPKGGL-ATPPPKGAPTTPAATPPSPKGGLATPPPK--GAPTTPAATPPS 1181

Query: 1087 PHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSP----AARMPGMSPANPSLHSPVPDAS 1142
            P G L  ++P    SP G     P +P  + PSP    A   P  +P  P+   P P   
Sbjct: 1182 PKGGL--ATP----SPKGA----PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1231

Query: 1143 HSPRAGTSSQTMPTNMPPPRK----LPQRSWAASIPTILTHSALNILLLP----SPTPGL 1194
             +  +   + T P   PP  K     P    A + P     S    L  P    +P P +
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAV 1291

Query: 1195 V--PGLAGSYLCSP 1206
            V  P   G    SP
Sbjct: 1292 VTPPSPKGGPATSP 1305



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 70/258 (27%), Positives = 92/258 (35%), Gaps = 47/258 (18%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQS 1043
            PPSP GG    S      PP    P PK  G+  A P     ++  +    SP      +
Sbjct: 993  PPSPKGGPATPSPKGAPTPPAVTPPSPK--GSPAATPFPKGASTPPAATPPSPKGSPAAT 1050

Query: 1044 PGNLHAASSPSGALRAPS--PAS----FVPTPP-------------PSSHGISIGPGASF 1084
            P    A ++P+  L +P   PA+      PTPP             PS  G  + P A+ 
Sbjct: 1051 PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP 1110

Query: 1085 ASPHGTLD-------PSSPY-TMVSPSGRAGN-----WPGSPQVSGPSP----AARMPGM 1127
             SP G L        P++P  T  SP G          P +P  + PSP    A   P  
Sbjct: 1111 PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170

Query: 1128 SPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRK----LPQRSWAASIPTILTHSALN 1183
            +P  P+   P P    +  +   + T P   PP  K     P    A + P     S   
Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230

Query: 1184 ILLLPSP-----TPGLVP 1196
             L  PSP     TP   P
Sbjct: 1231 GLATPSPKGAPTTPAATP 1248



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 64/240 (26%), Positives = 81/240 (33%), Gaps = 33/240 (13%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPK----QPGTSGA--YPLTSPPTSYHSTVNQSPS 1037
            PPSP GG            P    P PK     P   GA   P  +PP+        SP 
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215

Query: 1038 MMHTQSPGNLHAASSPSGALRAPSPASFVPTP---PPSSHGISIGPGASFA-SPHGTLDP 1093
               T          SP G L  PSP     TP   PPS  G    P    A +P     P
Sbjct: 1216 GAPTTPAAT---PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272

Query: 1094 SSPYTMVSPSGRAGNWP---------GSPQVSGPSPAARMPGMSPANP--SLHSPVPDAS 1142
            S    + +P  +    P         G P  S P  A   P  +P +P  S  +P P  +
Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332

Query: 1143 HSPRAGT-----SSQTMPTNMPPPRKLPQRSWAASIPT----ILTHSALNILLLPSPTPG 1193
             +P A T      + T+P   P  +  P    +   PT      +H     +  PSP  G
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 56/232 (24%), Positives = 90/232 (38%), Gaps = 51/232 (21%)

Query: 1002 PPPQQQPFPKQPGTSGA--------YPLTSP----------------PTSYHSTVNQSPS 1037
            P P++ P PKQ  TS +         P+ +P                P+S    +  + +
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532

Query: 1038 MMHTQSPGNL---HAASSPSGALRAPSPASFVPTP-----PPSSHGISIGPGASFASPHG 1089
            ++  ++P  L    A   P+  + +P     +PTP      PSS   S  P  + ++  G
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592

Query: 1090 TLDPSS---PYTMVSPSGRAGNWPGSPQVSGPS----PAARMPGMSPANPSL-HSPVPDA 1141
               P     P  + SPS +    P  P V+ PS    PA   P  +P +P +  S + D+
Sbjct: 1593 APSPKELLIPPAVTSPSPKEA--PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS 1650

Query: 1142 SHSPRAGTSSQTMPTNMPPPRK-LPQRSWAASIPTILTHSALNILLLPSPTP 1192
              SP + T    M   +P   K LP +    ++  +L   A      P  TP
Sbjct: 1651 PTSPASVTCK--MGATVPQASKGLPAKKGPTALKEVLVAPA------PESTP 1694



 Score = 39.7 bits (91), Expect = 0.021
 Identities = 60/237 (25%), Positives = 85/237 (35%), Gaps = 40/237 (16%)

Query: 984  PPSPIGGDMMD--------------SLISQLQPPPQQ---QPFPKQPGTSGAYPLTSPPT 1026
            PPSP GG                  SL   L  PP +    P    P +    P TSPP 
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK 1307

Query: 1027 SYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFAS 1086
               +    +P      SP        P GA   P+P +     PPS  G    P  + +S
Sbjct: 1308 GAPTPPAATPP-----SPKGSPGTPPPKGA---PTPPA---VTPPSPKGTPTLPATTPSS 1356

Query: 1087 PHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPS----PAARMPGMSPANPSLHSPVPDAS 1142
              G   PSS      P+    +  G P ++ PS    PA   P   P +P++    P  +
Sbjct: 1357 KGGPTTPSSKEGPTPPAATPSH-KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415

Query: 1143 HSPRAGTSSQTMPT--NMPPPRKLP---QRSWAASIPT--ILTHSALNILLLPSPTP 1192
             +          P+  ++ PP   P   +++ A S P     T S+     LP+ TP
Sbjct: 1416 PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP 1472



 Score = 38.9 bits (89), Expect = 0.036
 Identities = 45/211 (21%), Positives = 76/211 (36%), Gaps = 16/211 (7%)

Query: 955  PAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPP----QQQPFP 1010
            PAP     +          ++ S       P P   +     +S + P P    Q+    
Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747

Query: 1011 KQPGTSGAY----PLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFV 1066
               G   ++    PL  P +   + +  +        P +   +++PS  +  P   S V
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV 1807

Query: 1067 PTPPPSSHGISIGPGASFASPHGTLDPSSP---YTMVSPSGRAGNWP-GSPQVSGPSPAA 1122
            PT PP    +   PG    SP   L P+       ++ P   +G  P  S  V+ P+P  
Sbjct: 1808 PTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTP-- 1865

Query: 1123 RMPGMSPANPSLHSPVPDASHSPRAGTSSQT 1153
            +  G+    PS   PV    ++  +GT S +
Sbjct: 1866 KSAGIPVPTPSAKQPV--TKNNKGSGTESDS 1894


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 57/228 (25%), Positives = 86/228 (37%), Gaps = 30/228 (13%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            PP      P  P +S     T+ P +  +T    PS   +  P    A  +P     AP 
Sbjct: 169  PPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSS--SAPPETTAAPPTPPATTPAPP 226

Query: 1062 PASFVP---TPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGP 1118
             +S  P     PP+    +  P +S A P  T  P +P               S     P
Sbjct: 227  SSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTP---------------SATTLDP 271

Query: 1119 SPAARMPGMS--PANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTI 1176
            S A+  P  +  P  PS  +P P +S +P+  T++     N  P    P  S  ++ PT 
Sbjct: 272  SSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTH 331

Query: 1177 LTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRII 1224
             T +++      +  P   PG       + + RFL  + M+  L RII
Sbjct: 332  QTTTSVTTQTTTTKQPTSAPGQ------NKISRFL--LYMKNLLNRII 371



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 39/173 (22%), Positives = 59/173 (34%), Gaps = 16/173 (9%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG------NLHAASSPSG 1055
            P P Q P      +S   P     T   S    S S   T  P       N    SS   
Sbjct: 85   PNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSREN 144

Query: 1056 ALRAPSPASFVPTPPPSSHGISIGPGASFAS----PHGTLDPSSPYTMVSPSGRAGNWPG 1111
               + S A+  P   P+    +  P    A+    P  +  P +     +PS      P 
Sbjct: 145  VNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPS 204

Query: 1112 S---PQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPP 1161
            S   P+ +   P    P  +PA PS  +P P+ + +P   +++   P +   P
Sbjct: 205  SSAPPETTAAPPTP--PATTPAPPSSSAP-PETTAAPPTPSATTPAPLSSSAP 254



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%)

Query: 1119 SPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP---TNMPPPRKLPQRSWAA 1171
            SPA +    +P  PS  +P P +S +P   T++   P   T  PP    P  + AA
Sbjct: 159  SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA 214


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 57/228 (25%), Positives = 86/228 (37%), Gaps = 30/228 (13%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            PP      P  P +S     T+ P +  +T    PS   +  P    A  +P     AP 
Sbjct: 169  PPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSS--SAPPETTAAPPTPPATTPAPP 226

Query: 1062 PASFVP---TPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGP 1118
             +S  P     PP+    +  P +S A P  T  P +P               S     P
Sbjct: 227  SSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTP---------------SATTLDP 271

Query: 1119 SPAARMPGMS--PANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTI 1176
            S A+  P  +  P  PS  +P P +S +P+  T++     N  P    P  S  ++ PT 
Sbjct: 272  SSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTH 331

Query: 1177 LTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRII 1224
             T +++      +  P   PG       + + RFL  + M+  L RII
Sbjct: 332  QTTTSVTTQTTTTKQPTSAPGQ------NKISRFL--LYMKNLLNRII 371



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 39/173 (22%), Positives = 59/173 (34%), Gaps = 16/173 (9%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG------NLHAASSPSG 1055
            P P Q P      +S   P     T   S    S S   T  P       N    SS   
Sbjct: 85   PNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSREN 144

Query: 1056 ALRAPSPASFVPTPPPSSHGISIGPGASFAS----PHGTLDPSSPYTMVSPSGRAGNWPG 1111
               + S A+  P   P+    +  P    A+    P  +  P +     +PS      P 
Sbjct: 145  VNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPS 204

Query: 1112 S---PQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPP 1161
            S   P+ +   P    P  +PA PS  +P P+ + +P   +++   P +   P
Sbjct: 205  SSAPPETTAAPPTP--PATTPAPPSSSAP-PETTAAPPTPSATTPAPLSSSAP 254



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%)

Query: 1119 SPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP---TNMPPPRKLPQRSWAA 1171
            SPA +    +P  PS  +P P +S +P   T++   P   T  PP    P  + AA
Sbjct: 159  SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA 214


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 57/228 (25%), Positives = 86/228 (37%), Gaps = 30/228 (13%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            PP      P  P +S     T+ P +  +T    PS   +  P    A  +P     AP 
Sbjct: 169  PPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSS--SAPPETTAAPPTPPATTPAPP 226

Query: 1062 PASFVP---TPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGP 1118
             +S  P     PP+    +  P +S A P  T  P +P               S     P
Sbjct: 227  SSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTP---------------SATTLDP 271

Query: 1119 SPAARMPGMS--PANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTI 1176
            S A+  P  +  P  PS  +P P +S +P+  T++     N  P    P  S  ++ PT 
Sbjct: 272  SSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTH 331

Query: 1177 LTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRII 1224
             T +++      +  P   PG       + + RFL  + M+  L RII
Sbjct: 332  QTTTSVTTQTTTTKQPTSAPGQ------NKISRFL--LYMKNLLNRII 371



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 39/173 (22%), Positives = 59/173 (34%), Gaps = 16/173 (9%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG------NLHAASSPSG 1055
            P P Q P      +S   P     T   S    S S   T  P       N    SS   
Sbjct: 85   PNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSREN 144

Query: 1056 ALRAPSPASFVPTPPPSSHGISIGPGASFAS----PHGTLDPSSPYTMVSPSGRAGNWPG 1111
               + S A+  P   P+    +  P    A+    P  +  P +     +PS      P 
Sbjct: 145  VNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPS 204

Query: 1112 S---PQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPP 1161
            S   P+ +   P    P  +PA PS  +P P+ + +P   +++   P +   P
Sbjct: 205  SSAPPETTAAPPTP--PATTPAPPSSSAP-PETTAAPPTPSATTPAPLSSSAP 254



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%)

Query: 1119 SPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP---TNMPPPRKLPQRSWAA 1171
            SPA +    +P  PS  +P P +S +P   T++   P   T  PP    P  + AA
Sbjct: 159  SPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAA 214


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 80/301 (26%), Positives = 122/301 (40%), Gaps = 47/301 (15%)

Query: 986  SPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG 1045
            S  G  ++ S+   L P     P P     SGA P  S  T   +T   +PS+  +Q+PG
Sbjct: 1466 SASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLAT---APSLSSSQTPG 1522

Query: 1046 NLHAASSPSGALRAPSPASFVP----TPPPSSHGISIGPGASFASPHGTLDPSSP--YTM 1099
            +          L AP+ +S VP    T  P+   + + P ++ ASP  +    +P   ++
Sbjct: 1523 H--------PLLLAPT-SSHVPGLNSTVAPACSPVLV-PASALASPFPSAPNPAPAQASL 1572

Query: 1100 VSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAG---TSSQTMPT 1156
            ++P+  A     +P     +P   +   SPA P   +P+P  + SP A     SSQT P 
Sbjct: 1573 LAPASSASQALATPLAPMAAPQTAILAPSPAPPL--APLPVLAPSPGAAPVLASSQT-PV 1629

Query: 1157 NMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGSVIM 1216
             +  P   P  S A++ P            +P+PTP L P    + L +P+   L S   
Sbjct: 1630 PVMAPSSTPGTSLASASP------------VPAPTPVLAPSSTQTMLPAPVPSPLPSPAS 1677

Query: 1217 RRHLQRI----------IQQETLQLINSNEPGVIMFKTDALKCRVALSPKTNQTLQLKVT 1266
             + L                +TL L   N  G    +T +L    +L P   QTL L   
Sbjct: 1678 TQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPG 1737

Query: 1267 P 1267
            P
Sbjct: 1738 P 1738



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 65/232 (28%), Positives = 91/232 (39%), Gaps = 37/232 (15%)

Query: 995  SLISQLQPPPQQQPFPKQPGTSGAYPLTSP-PT--SYHSTVNQ-SPSMMHTQSPGNLHAA 1050
            +LI  + P P   P    P ++   P T+P PT  S     NQ  P+M++      +   
Sbjct: 1258 ALIQAVAPTPGPTPVSVLPSST---PSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVR 1314

Query: 1051 SSPSGALRAPSPASFVPTPPPSSHGISIGPGASFAS---PHGTLD----PSSPYTMVSPS 1103
             +P   L    P +  P PP S     + P  +      P  TL     P    T+V P 
Sbjct: 1315 QAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPL 1374

Query: 1104 GRAGNWPGSPQVSGPSPAA---------RMPGMSPANPSLHSPVPDASH--SPRAGTSSQ 1152
             +  + P SP+VS  +P A          +P   P   S   P+P++S   SP + T S 
Sbjct: 1375 LKLVHSP-SPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSV 1433

Query: 1153 --------TMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVP 1196
                    ++PT +P P   P       I   LT SA    LL S TP L P
Sbjct: 1434 PLSSSLPISVPTTLPAPASAP---LTIPISAPLTVSASGPALLTSVTPPLAP 1482



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 48/185 (25%), Positives = 68/185 (36%), Gaps = 39/185 (21%)

Query: 1007 QPFPKQPGTS-----------GAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSG 1055
            QP PKQ G +           G  P+  PP    S    +P  +    P +L  ++SP+G
Sbjct: 999  QPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSA-QPTPGPVPQVLPASLMVSASPAG 1057

Query: 1056 -----ALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWP 1110
                 A R P P    P  P S     + P +      GT  P +P   + P+       
Sbjct: 1058 PPLIPASRPPGPVLLPPLQPNSGSLPQVLP-SPLGVLSGTSRPPTPTLSLKPTP------ 1110

Query: 1111 GSPQVSGPSPAARMPGMSPANPSLHSPV---PDASHSPRAGTSSQTMP-----TNMPPPR 1162
                   P+P    P   P + SL  P+   P  +  P A T++ T       T +P P 
Sbjct: 1111 -------PAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPT 1163

Query: 1163 KLPQR 1167
              PQR
Sbjct: 1164 PAPQR 1168



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 61/228 (26%), Positives = 86/228 (37%), Gaps = 32/228 (14%)

Query: 1008 PFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALR-----APSP 1062
            PFP  P  + A      P S  S    +P +    +P     A SP+  L      APSP
Sbjct: 1558 PFPSAPNPAPAQASLLAPASSASQALATP-LAPMAAPQTAILAPSPAPPLAPLPVLAPSP 1616

Query: 1063 -------ASFVPTP---PPSSHGISIGPGASFASPHGTLDPSSPYTMV-SPSGRAGNWPG 1111
                   +S  P P   P S+ G S+   +   +P   L PSS  TM+ +P       P 
Sbjct: 1617 GAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPA 1676

Query: 1112 SPQ--VSGPSPAARMPGMSPA--------NPSLHSPVPDASHSPRAG---TSSQTMPTNM 1158
            S Q     P+ A  + G SP+        NP    P    S +P +    T +QT+    
Sbjct: 1677 STQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAP 1736

Query: 1159 PPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSP 1206
             PP    Q    A  P +   S +     P+ T  L P  + + L +P
Sbjct: 1737 GPPLGPTQTLSLAPAPPLAPASPVG--PAPAHTLTLAPASSSASLLAP 1782



 Score = 38.9 bits (89), Expect = 0.036
 Identities = 52/199 (26%), Positives = 69/199 (34%), Gaps = 27/199 (13%)

Query: 976  RSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQS 1035
            RS++  ++ P PIGG    +  S L  PPQQ    ++    G     SP           
Sbjct: 2794 RSMSGPESSP-PIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSP----------- 2841

Query: 1036 PSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDP-S 1094
                     G L A + P+   R   P     +P  +  G+   P ++        DP  
Sbjct: 2842 -----ENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVP 2896

Query: 1095 SPYTMV--SPSGRAGNWPGSPQVSGPSPAAR-MPGMSPANPSLHSPVPDASHSPRAGTSS 1151
             P T++   P       PG PQ  GP P  R  P +SP         P A   P  GT S
Sbjct: 2897 GPETLIVADPVLEPQLIPG-PQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTIS 2955

Query: 1152 QTMPTN-----MPPPRKLP 1165
                 N      PPP   P
Sbjct: 2956 SAGDGNSESRTQPPPHPSP 2974


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 51/171 (29%), Positives = 69/171 (40%), Gaps = 25/171 (14%)

Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062
            PP     P  PG     P   PPTS    V+     +H  +PG       P+  +  P+P
Sbjct: 303  PPAPGVHPPAPGVHPPAPGVHPPTS---GVHPPAPGVHPPAPG----VHPPAPGVHPPAP 355

Query: 1063 ASFVPTP---PPSSHGISI-GPGASFASPHGTLDPSSPYTMVSPSGRAGNWPG-SPQVSG 1117
                P P   PP S G+    PG   A+P   + P +P       G     PG  PQ  G
Sbjct: 356  GVHPPAPGVHPPPSAGVHPQAPGVHPAAP--AVHPQAPGVHPPAPGMHPQAPGVHPQPPG 413

Query: 1118 PSPAA-----RMPGMSPANPSLH--SPVPDASHSPRAGTSSQTMPTNMPPP 1161
              P+A     + PG+ P+NP +H  +P+P     P         P N+PPP
Sbjct: 414  VHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEG----PGNIPPP 460



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 46/170 (27%), Positives = 58/170 (34%), Gaps = 19/170 (11%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            PPP     P +P    + P   PP            +     P    A S P G  + P 
Sbjct: 234  PPPLMNGLPPRPPLPESLP--PPPPG---------GLPLPPMPPTGPAPSGPPGPPQLPP 282

Query: 1062 PASFVPTPPPSSHGISIG---PGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGP 1118
            PA  V  P P  H  + G   P      P   + P +P      SG     P +P V  P
Sbjct: 283  PAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVH---PPAPGVHPP 339

Query: 1119 SPAAR--MPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQ 1166
            +P      PG+ P  P +H P P     P AG   Q    +   P   PQ
Sbjct: 340  APGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQ 389



 Score = 30.8 bits (68), Expect = 9.9
 Identities = 25/80 (31%), Positives = 31/80 (38%), Gaps = 11/80 (13%)

Query: 1000 LQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059
            + PPP     P+ PG   A P   P       V+     MH Q+PG       P G    
Sbjct: 364  VHPPPSAGVHPQAPGVHPAAPAVHPQA---PGVHPPAPGMHPQAPG---VHPQPPGV--H 415

Query: 1060 PSPASFVPTPP---PSSHGI 1076
            PS     P PP   PS+ G+
Sbjct: 416  PSAPGVHPQPPGVHPSNPGV 435


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 54/198 (27%), Positives = 73/198 (36%), Gaps = 28/198 (14%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            PPP Q P P  P   GA               Q+P    + +P     A++P   L+ P 
Sbjct: 727  PPPAQDPAPATPVAKGA-----------GLGPQAPDSQASPAPAPQIPAAAP---LKGPG 772

Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPA 1121
            P+S     P   H   +G      SPH T  PS P +      R  + P       P   
Sbjct: 773  PSS----SPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAP 828

Query: 1122 ARMPGMSPANPSLHSPVPDASHSPRAGTSSQ--TMPTNMPPPRKLPQRSWAASIPTILTH 1179
              +PG+      L  P P ++ +P A    Q    P + PP   LP    A  +P   T 
Sbjct: 829  PTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPP---APHLPPSSTS 885

Query: 1180 SAL-----NILLLPSPTP 1192
            SA+         LP+PTP
Sbjct: 886  SAVASSSETSSRLPAPTP 903



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 67/240 (27%), Positives = 95/240 (39%), Gaps = 65/240 (27%)

Query: 1002 PPPQQQPFPKQPGTSGA--YPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059
            PPP   P P  PG       P + PP      +  +P +  + +   + ++S  S  L A
Sbjct: 844  PPPASNPAPTAPGPPQPPLRPQSQPP---EGPLPPAPHLPPSSTSSAVASSSETSSRLPA 900

Query: 1060 PSPASF------------VPTPPPSSHGISIGPGASFASPHGTLD------PSSPYTMV- 1100
            P+P+ F             PTPPP+ H +   P A    P  T        P+ P     
Sbjct: 901  PTPSDFQLQFPPSQGPHKSPTPPPTLHLVP-EPAAPPPPPPRTFQMVTTPFPALPQPKAL 959

Query: 1101 ------SPSG-----RAGNWPGSPQVS---GP--SPAA------RMPGMSPANPSLHSPV 1138
                   PSG     +AG  P +PQ S   GP  SPAA      + P  +P  PS H+P 
Sbjct: 960  LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPS-HAPA 1018

Query: 1139 PDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGL 1198
            P    +P A        T +PP      +++A+++PT      LN+    S  PG   GL
Sbjct: 1019 P----APMAA-------TGLPPLLPAENKAFASNLPT------LNVAKAASSGPGKPSGL 1061



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 53/219 (24%), Positives = 79/219 (36%), Gaps = 33/219 (15%)

Query: 999  QLQPPPQQ---QPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMM------HTQSPGNL-- 1047
            Q   PPQ    QP P    +     L  PP++  + +    S+        +Q P +   
Sbjct: 654  QAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEG 713

Query: 1048 -HAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRA 1106
             H +   S  + AP PA       P + G  +GP A             P +  SP+  A
Sbjct: 714  PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQA-------------PDSQASPA-PA 759

Query: 1107 GNWPGSPQVSGPSPAA--RMPGMSPANPSLHSPVPDASHSPRAGTS---SQTMPTNMPPP 1161
               P +  + GP P++   +P  +P   S H P P  +  P    S   S + P + PP 
Sbjct: 760  PQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPL 819

Query: 1162 RKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAG 1200
               P      ++P I      N L +P P     P   G
Sbjct: 820  HPCPPPQAPPTLPGIFV--IQNQLGVPPPASNPAPTAPG 856



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 49/217 (22%), Positives = 77/217 (35%), Gaps = 44/217 (20%)

Query: 1020 PLTSPPTSYHSTVNQSPSMMHT------QSPGNLHAASSPSGALRAPSPASFVPTPPPSS 1073
            P+ +P +  HS    S + +        Q P +L A S P+ +  AP+            
Sbjct: 528  PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPA------------ 575

Query: 1074 HGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPS 1133
                 GP A+      TL PS+   + +P G       +      +P   +     A P+
Sbjct: 576  -----GPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630

Query: 1134 LHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPG 1193
            + +P+P     P+A           PP    PQ   AA+ P   T         P P+PG
Sbjct: 631  VSTPLPLGLQQPQA---------QQPPQAPTPQ---AAAPPQATT---------PQPSPG 669

Query: 1194 LVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQQETLQ 1230
            L        L  P      +++ +  LQ  + QE  Q
Sbjct: 670  LASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ 706



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 43/205 (20%), Positives = 71/205 (34%), Gaps = 26/205 (12%)

Query: 1003 PPQQQPFPKQP-GTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            P Q QP P  P  T+    +T PP++         +M++T  P  L   ++P+ A    +
Sbjct: 567  PTQSQPAPAGPAATTVLQGVTLPPSAV--------AMLNT--PDGLVQPATPAAATGEAA 616

Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSP---------YTMVSPSGRAGNWP-- 1110
            P   V   P +   +S         P     P +P          T   PS    + P  
Sbjct: 617  PVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEK 676

Query: 1111 ---GSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQR 1167
               G P  + P+       +    P   S  P ++  P     +  +  + PPP + P  
Sbjct: 677  IVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVI-VSAPPPAQDPAP 735

Query: 1168 SWAASIPTILTHSALNILLLPSPTP 1192
            +   +    L   A +    P+P P
Sbjct: 736  ATPVAKGAGLGPQAPDSQASPAPAP 760


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 60/213 (28%), Positives = 87/213 (40%), Gaps = 36/213 (16%)

Query: 984  PPSPIGGDMMDSLISQLQPP------PQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPS 1037
            PP+ +    +++L S   PP      P   P  + P      PL +PP+   +   ++PS
Sbjct: 526  PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585

Query: 1038 MMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSS-HGISIGPGASFASPHGTLDPSSP 1096
             + T  P    A +SP        P S + TPPP +   +++ P  +  SP  +  P SP
Sbjct: 586  SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS-PPLSP 644

Query: 1097 YTMVSPSGRAGNW------------PGSPQVSGP---------SPAARMPGMSPANPSLH 1135
              + +PS +A N             P SP V  P         SP+A  P  +P  PSL 
Sbjct: 645  --LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP--PSLA 700

Query: 1136 SPVPDASHSPRAG---TSSQTMPTNMPPPRKLP 1165
            +P      SP A    + S T P   PPP   P
Sbjct: 701  APPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 78/254 (30%), Positives = 98/254 (38%), Gaps = 52/254 (20%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVN-QSP---SMM 1039
            PPSP+     ++  S   PPPQ  P    P   G   L SPP S  +T   Q+P   ++ 
Sbjct: 572  PPSPLTTPPPETPSSIATPPPQAPPALASPPLQG---LPSPPLSPLATPPPQAPPXLALP 628

Query: 1040 HTQSPGNLHAASSPSGALRAPSP------------ASFVPTP---------PPSSHGISI 1078
              Q+P +   AS P   L  PSP            A F P P         PP+S  +S 
Sbjct: 629  PLQAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS- 686

Query: 1079 GPGA--------SFASPHGTLDPSSPYT-MVSPSGRAGNWPGSPQVSGPSPAARMPGMSP 1129
             P A        S A+P   + PS P +  +SPS        +P    P P A  P   P
Sbjct: 687  -PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS-------ATPPPQAPPPLAAPPLQVP 738

Query: 1130 ANPSLHSPV-PDASHSPRAGTSSQTMPTNMP--PPRKLPQRSWAASIPTILTHSALNIL- 1185
             +P    P+ P A+  PR        P  +P  PP  LP    A   P      A   L 
Sbjct: 739  PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798

Query: 1186 LLPSPTPGLVPGLA 1199
             LPSP P   PG A
Sbjct: 799  ALPSP-PASFPGQA 811



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 58/233 (24%), Positives = 96/233 (41%), Gaps = 28/233 (12%)

Query: 985  PSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSP 1044
            P+ +   ++ +  S    PP Q PF   P +    P  +PP+    ++   P  +    P
Sbjct: 653  PNALAVHLLQAPFSPPPSPPVQAPF-SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711

Query: 1045 GNLHAASSPSGALRAPSPASF----VPTPPPSSHGISIGPGAS--------FASPHGTLD 1092
             +   + S +   +AP P +     VP  PP+S  +S  P A+         A+P   + 
Sbjct: 712  ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS--PSATPPPRVPPLLAAPPLQVP 769

Query: 1093 PSSPYTM-----VSPSGRAGNWPGSPQVSG-PSPAARMPGMSPANPSLHSPV-PDASHSP 1145
            PS P ++       P  +A     +P +   PSP A  PG +P +PS   P+ P A+  P
Sbjct: 770  PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829

Query: 1146 RA----GTSSQTMPTNMP--PPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192
            +A          +P + P  P  + P+R       T ++   L + L P P P
Sbjct: 830  QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 114/441 (25%), Positives = 158/441 (35%), Gaps = 51/441 (11%)

Query: 1003 PPQQQPFPKQPGTSGAYPLTSPP--TSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAP 1060
            PPQ  P P++       PL+S P  T   S     P      +   L A   PS  L  P
Sbjct: 282  PPQVTP-PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP 340

Query: 1061 SP-ASFVPTPPPSSHGISIGPGA--SFASPHGTLDP--SSPYTMVSPSGRAGNWPGSPQV 1115
             P A   P+ PPS   +   P    S A P  T  P  + P     P  +  +   SP +
Sbjct: 341  LPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL 400

Query: 1116 SGPSPAARMPGMSPANPSLHSPVPDASHS-----PRAGTSSQTMPTNMPPPRKLPQRSWA 1170
              P     +  +  A  SL SP   A+HS     PR   +S T P+    P   P  S  
Sbjct: 401  QAPPSPLALSSLQ-ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR---PASTPPDSPP 456

Query: 1171 ASIPTILTHSA-LNILLLPSPTPGLVPGLAGSYLCSPLERF--LGSVIMRRHLQRIIQQE 1227
               P  L  S  L   L P+ +P     L+      PL+    L S   +  L  +I   
Sbjct: 457  LQAPLSLPASPPLQTSLSPAVSP-----LSSPLTIHPLQALSSLASHSPQAPLSSLIMPP 511

Query: 1228 TLQLINSNEPGVIM-----FKTDALKCRVALSPKTNQTLQLKVTPENAG----------Q 1272
             L+  +S  P  +        T  L+   +L+P   QT    +T  +            Q
Sbjct: 512  -LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQ 570

Query: 1273 WKPDELQVLEKFFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQ- 1331
              P  L        + +A PP +A   +A   L G P+  L        L   P QA   
Sbjct: 571  APPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP------LATPPPQAPPX 624

Query: 1332 LKWNVQFCLTIPPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDM 1391
            L          PP++PP++P  TP+    + +   L L    S PP  PV    P     
Sbjct: 625  LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQ--APFSPPA 681

Query: 1392 ASGTTQQADIPRQQNSSVAAP 1412
            +   +  A  P Q   S+AAP
Sbjct: 682  SPPVSPSATPPSQAPPSLAAP 702



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 110/460 (23%), Positives = 162/460 (35%), Gaps = 75/460 (16%)

Query: 973  ARRRSVNEDDNPPSPIGGDMMDSLISQL---QPPPQQQPFPKQPGTSGAYPLTSPPTSYH 1029
            ARR +       PSP       +  +++   +P P  +P   +P T G     S   S H
Sbjct: 160  ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSS-ASEH 215

Query: 1030 STVNQSP------------------SMMHTQSPGNLHAASSPS--GALRAPS-PASFVPT 1068
            ST   SP                  S+  + +P +  A S PS  G  RAP+ P+   P 
Sbjct: 216  STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275

Query: 1069 PPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMS 1128
               +     + P    A+P      SSP    SPSG     P  P  +  +P   +P   
Sbjct: 276  GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR-PVPPPDNAATP---LPATL 331

Query: 1129 PANPSLHSPVPDASHSPRAGTSSQTM-------PTNMPPPRKLPQRSWAASIPTI----L 1177
            P +P L +P+P A  SP A  S QT+       P+  PP    P      S+ TI    +
Sbjct: 332  PPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQV 391

Query: 1178 THSALNILLLPSPTPGLVPGL-AGSYLCSPLERFLGSVIMRRHLQRIIQQETLQLINSNE 1236
             HS  +  L   P+P  +  L A + L SP  +   S      L    +Q    L + + 
Sbjct: 392  PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS-----FLTMSPRQTQASLTSPSR 446

Query: 1237 PGVIMFKTDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEKFFE---------- 1286
            P       D+   +  LS   +  LQ  ++P  +    P  +  L+              
Sbjct: 447  PA--STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL 504

Query: 1287 TRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQLKWNVQFCLTIPPSA 1346
            + +  PP +  + +A   L   P  +         LE  P  A          LT P   
Sbjct: 505  SSLIMPPLETQSSLAPPSLQTPPASLTTP-----PLENLPSLAPPPLQTASAPLTTPHLE 559

Query: 1347 PPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVP 1386
             P  P   P     S +         T+ PP+ P SI  P
Sbjct: 560  TPPCPAPCPLQAPPSPL---------TTPPPETPSSIATP 590



 Score = 38.5 bits (88), Expect = 0.048
 Identities = 48/174 (27%), Positives = 64/174 (36%), Gaps = 12/174 (6%)

Query: 983  NPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042
            +PP+   G    S  + L   P   P P+ P    A  L  PP+   S   Q+P    T 
Sbjct: 802  SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT- 860

Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSP-----Y 1097
             PG   + S P   L A +P    P PPPS    S   G   A  H +   S+P     Y
Sbjct: 861  -PGPDTSVSGPRLTL-ALAPG---PPPPPSRSPSSTLSGPDLAG-HSSSATSTPEELRGY 914

Query: 1098 TMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSS 1151
                  G A + P   +++   PAA   G +P      +P       P  G  S
Sbjct: 915  DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 968



 Score = 37.7 bits (86), Expect = 0.081
 Identities = 54/224 (24%), Positives = 72/224 (32%), Gaps = 43/224 (19%)

Query: 1002 PPPQQQPF---------PKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAAS- 1051
            PPPQ  P          P  P +        PPT    T    P +    +PG     S 
Sbjct: 827  PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 886

Query: 1052 SPSGALRAPSPA---SFVPTPPPSSHGISIGP-GASFASPHGTLD------------PSS 1095
            SPS  L  P  A   S   + P    G   GP G + ASP    +            P+ 
Sbjct: 887  SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 946

Query: 1096 PYTMVSPSGRAGNWPGSP------------QVSGPSPAARMPGMSPANPSLHSPVPDASH 1143
            P       G    WP +             +  GP  A   PG     PS  +    A+ 
Sbjct: 947  PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 1006

Query: 1144 SPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLL 1187
               AG SS++     P   +L +    A   +++ H     LLL
Sbjct: 1007 GAGAGASSRS-----PKQARLGELPLGALQASVVQHLLSRTLLL 1045


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 47/172 (27%), Positives = 71/172 (41%), Gaps = 18/172 (10%)

Query: 1003 PPQQQPFPKQPGT--SGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAP 1060
            PP     P+ P T    A PL  PP+ + S+    P  +    P   ++  +     RAP
Sbjct: 749  PPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAP 808

Query: 1061 SPASFVPTPPPS-----SHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGS--P 1113
             P +    P P+     ++   +G     +  HG +  SSPY  V P+      P +  P
Sbjct: 809  GPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVV--SSPYVGVGPAPPVAGLPSAPPP 866

Query: 1114 QVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLP 1165
            Q SGP  A  +   +    S+ +P+P  SH     T+ +  PT  PPP   P
Sbjct: 867  QFSGPELAMAVRPATTTVDSIQAPIP--SH-----TAPRPNPTPAPPPPCFP 911



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 44/140 (31%), Positives = 56/140 (40%), Gaps = 22/140 (15%)

Query: 1000 LQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059
            L PP    P+  QPG  G      PP   H+ +   P+    Q P   H     SGAL  
Sbjct: 991  LLPPQSPYPYAPQPGVLG-----QPPPPLHTQLYPGPA----QDPLPAH-----SGALPF 1036

Query: 1060 PSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPS 1119
            PSP    P  PP    ++ GP  S   P G    ++P T+  PS    + P    V  P+
Sbjct: 1037 PSPGPPQPPHPP----LAYGPAPS-TRPMG--PQAAPLTIRGPSSAGQSTPSPHLVPSPA 1089

Query: 1120 PAARMPGMSPANPSLHSPVP 1139
            P+   PG  P  P    P P
Sbjct: 1090 PSPG-PGPVPPRPPAAEPPP 1108



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 52/189 (27%), Positives = 62/189 (32%), Gaps = 20/189 (10%)

Query: 1001 QPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAP 1060
            QP P  QP P Q    G  P   P    H      P +   Q+PG L   S       AP
Sbjct: 954  QPQPHPQPHPSQ--AFGPQPPQQPLPLQH------PHLFPPQAPGLLPPQSPYP---YAP 1002

Query: 1061 SPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSP 1120
             P      PPP    +  GP       H    P        PS      P  P   GP+P
Sbjct: 1003 QPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPF-------PSPGPPQPPHPPLAYGPAP 1055

Query: 1121 AARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHS 1180
            + R  G   A  ++  P      +P         P+  P P  +P R  AA  P  L   
Sbjct: 1056 STRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPS--PGPGPVPPRPPAAEPPPCLRRG 1113

Query: 1181 ALNILLLPS 1189
            A    LL S
Sbjct: 1114 AAAADLLSS 1122



 Score = 38.9 bits (89), Expect = 0.036
 Identities = 52/218 (23%), Positives = 79/218 (36%), Gaps = 30/218 (13%)

Query: 992  MMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAAS 1051
            ++D  + +  PP    P P  P    +  + +            P  + +  P  +    
Sbjct: 707  LLDRELKKKPPPRPTAPKPLLPRREESEAVEA---------GDPPEELRSLPPDMVAGPR 757

Query: 1052 SPSGALRAPSPASFVPTPPPSSHGISIGPGASFAS---PHGTLDPSSPYTMVSPSGRAGN 1108
             P   L + +P  F P+P PS    S GPG  + S   P GT   S P  ++ P  RA  
Sbjct: 758  LPDTFLGSATPLHFPPSPFPS----STGPGPHYLSGPLPPGTY--SGPTQLIQP--RAPG 809

Query: 1109 WPGSPQVSGPS--PA-------ARMPGMSPANPSLHSPVPDASHSPR-AGTSSQTMPTNM 1158
                P   GP+  PA         +P  SP +  + SP      +P  AG  S   P   
Sbjct: 810  PHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFS 869

Query: 1159 PPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVP 1196
             P   +  R    ++ +I      +    P+PTP   P
Sbjct: 870  GPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPP 907



 Score = 36.6 bits (83), Expect = 0.18
 Identities = 50/187 (26%), Positives = 63/187 (33%), Gaps = 29/187 (15%)

Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPP----------------PSSHGISIGPGASFA 1085
            Q+P   H A  P+     P P   VP P                 P+ H  S G  A F 
Sbjct: 888  QAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFP 947

Query: 1086 SPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSP 1145
            +P     P  P+    PS   G  P  PQ   P P        P  P L  P     ++P
Sbjct: 948  APRIGPQP-QPHPQPHPSQAFG--PQPPQ--QPLPLQHPHLFPPQAPGLLPPQSPYPYAP 1002

Query: 1146 RAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCS 1205
            + G   Q      PPP    Q     +   +  HS    L  PSP P   P    +Y  +
Sbjct: 1003 QPGVLGQ------PPPPLHTQLYPGPAQDPLPAHS--GALPFPSPGPPQPPHPPLAYGPA 1054

Query: 1206 PLERFLG 1212
            P  R +G
Sbjct: 1055 PSTRPMG 1061



 Score = 35.8 bits (81), Expect = 0.31
 Identities = 38/150 (25%), Positives = 51/150 (34%), Gaps = 12/150 (8%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQS 1043
            P   + G     L +QL P P Q P P   G    +P   PP   H  +   P+   +  
Sbjct: 1002 PQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGAL-PFPSPGPPQPPHPPLAYGPA--PSTR 1058

Query: 1044 PGNLHAA----SSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM 1099
            P    AA      PS A ++      VP+P PS      GPG     P     P      
Sbjct: 1059 PMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSP-----GPGPVPPRPPAAEPPPCLRRG 1113

Query: 1100 VSPSGRAGNWPGSPQVSGPSPAARMPGMSP 1129
             + +    + P S      SP    P + P
Sbjct: 1114 AAAADLLSSSPESQHGGTQSPGGGQPLLQP 1143


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 56/202 (27%), Positives = 74/202 (36%), Gaps = 15/202 (7%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLT--SPPTSYHS--TVNQSPSMMHTQSPGNLHAASSPSGAL 1057
            PPP   P P    T+   P T  SPPT+  S  T   SP    T +P      S P+   
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507

Query: 1058 RAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM-VSPSGRAGNWPGSPQVS 1116
              P PAS    PP ++      P  +  +P  T  PS P T  ++P       P +   S
Sbjct: 1508 ITP-PASTTTLPPTTTPS---PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1563

Query: 1117 GPSPAARMPG--MSPANPSLHSPVPDA----SHSPRAGTSSQTMPTNMPPPRKLPQRSWA 1170
             P      P    +P+ P+  +P P      +  P    S  T  T  PPP   P     
Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTT 1623

Query: 1171 ASIPTILTHSALNILLLPSPTP 1192
              I    + + L     PSP P
Sbjct: 1624 TPITPPTSTTTLPPTTTPSPPP 1645



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 50/177 (28%), Positives = 70/177 (39%), Gaps = 19/177 (10%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            PPP   P P    T+   P T+P     +T    P+   T SP      ++PS     PS
Sbjct: 1432 PPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTT--TPSP----PTTTPSPPTTTPS 1485

Query: 1062 PASFVPTPPPSSHGIS------IGPGASFASPHGTLDPSSPYTMVS--PSGRAGNWPGSP 1113
            P +   T PP +   S      I P AS  +   T  PS P T  +  P     + P + 
Sbjct: 1486 PPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1545

Query: 1114 QVSGPSPAARMPGM---SPANPSLHSPVPDASHSPRAGT--SSQTMPTNMPPPRKLP 1165
             ++ P+    +P     SP   +  +P P  + SP   T  S  T+ T  PPP   P
Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 54/190 (28%), Positives = 67/190 (35%), Gaps = 24/190 (12%)

Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062
            PP   P P    T+   P T+P  S  +T   +P    T SP      + P     +P P
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTP--SPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP-P 1457

Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAA 1122
             S   TPPP++            SP  T  PS P T  SP       P  P  + PSP  
Sbjct: 1458 ISTTTTPPPTTT----------PSPP-TTTPSPPTTTPSPPTTTTTTP--PPTTTPSP-- 1502

Query: 1123 RMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSAL 1182
              P  +P  P    P    +  P    S  T  T  PPP   P       I    + + L
Sbjct: 1503 --PTTTPITP----PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL 1556

Query: 1183 NILLLPSPTP 1192
                 PSP P
Sbjct: 1557 PPTTTPSPPP 1566



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 56/219 (25%), Positives = 75/219 (34%), Gaps = 17/219 (7%)

Query: 985  PSPIGGDMMDSLISQLQPPPQQQPFPKQ--PGTSGAYPLTSPPTSYHS---TVNQSPSMM 1039
            PSP          +   PPP   P P    P T  A   T PPT+  S   T   +P   
Sbjct: 1477 PSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT 1536

Query: 1040 HTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPS----- 1094
             T SP      + P+     P   +  P+PPP++   +  P  +  SP  T  PS     
Sbjct: 1537 TTPSPPTTTPITPPTSTTTLPPTTT--PSPPPTT--TTTPPPTTTPSPPTTTTPSPPTIT 1592

Query: 1095 --SPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQ 1152
              +P    +PS         P  + PSP    P   P + +   P    S  P   T+  
Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1652

Query: 1153 TMPTNMPPPRKLPQRS-WAASIPTILTHSALNILLLPSP 1190
               T  PP    P       + P   T  +  I   PSP
Sbjct: 1653 PTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSP 1691



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 53/203 (26%), Positives = 82/203 (40%), Gaps = 29/203 (14%)

Query: 997  ISQLQPPPQQQPFPKQPGTSGAYPLT--SPPTSYHSTVNQSPSMMH-TQSPGNLHAASSP 1053
            I+   PPP   P P    T+   P T  SPPT+   T   S + +  T +P      ++ 
Sbjct: 1591 ITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1650

Query: 1054 SGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSP 1113
                  PSP +   TP P        P  +  +P  T  PSSP T  +PS      P + 
Sbjct: 1651 PPPTTTPSPPTTT-TPSP--------PITTTTTPPPTTTPSSPIT-TTPS------PPTT 1694

Query: 1114 QVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASI 1173
             ++ PSP       +P++P   +  P ++ +P    ++ T P+  P     P  +   ++
Sbjct: 1695 TMTTPSPTT-----TPSSPITTTTTPSSTTTPSPPPTTMTTPS--PTTTPSPPTTTMTTL 1747

Query: 1174 PTILTHSALNILLLPSPTPGLVP 1196
            P   T S L    LP   P + P
Sbjct: 1748 PPTTTSSPLTTTPLP---PSITP 1767



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 12/144 (8%)

Query: 1057 LRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVS 1116
            +  PSP +  P+PPP+S   ++ P  + + P  T     P T  SP       P  P  +
Sbjct: 1396 ITTPSPPTTTPSPPPTS-TTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP--PPTT 1452

Query: 1117 GPSP-----AARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRK----LPQR 1167
             PSP         P  +P+ P+     P  + SP   T++   PT  P P       P  
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512

Query: 1168 SWAASIPTILTHSALNILLLPSPT 1191
            S     PT            P PT
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPT 1536



 Score = 38.9 bits (89), Expect = 0.036
 Identities = 37/155 (23%), Positives = 58/155 (37%), Gaps = 34/155 (21%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            PP    P P    T+   P T+P +   +T +   + M T SP      SSP      PS
Sbjct: 1659 PPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT--TPSSPITTTTTPS 1716

Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPA 1121
             ++  P+PPP+          +  +P  T  PS P T ++                    
Sbjct: 1717 -STTTPSPPPT----------TMTTPSPTTTPSPPTTTMT-------------------- 1745

Query: 1122 ARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPT 1156
              +P  + ++P   +P+P +   P     S T PT
Sbjct: 1746 -TLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPT 1779



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 46/195 (23%), Positives = 75/195 (38%), Gaps = 21/195 (10%)

Query: 1013 PGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPS 1072
            P  +G    T+ P +  +TV  +P+   TQ+    H +++P   L   +P     TP  S
Sbjct: 4165 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTS 4224

Query: 1073 SHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANP 1132
                S  P     +   TL P+   T  +P       P +P  + P+  +    +SP   
Sbjct: 4225 RSTSS--PLTESTTLLSTLPPAIEMTSTAP-------PSTP--TAPTTTSGGHTLSPPPS 4273

Query: 1133 SLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192
            +  SP    +     G+SS       P P  +   + +A  PT    S  +I+     T 
Sbjct: 4274 TTTSPPGTPTRGTTTGSSS------APTPSTVQTTTTSAWTPTPTPLSTPSII----RTT 4323

Query: 1193 GLVPGLAGSYLCSPL 1207
            GL P  +   +C  L
Sbjct: 4324 GLRPYPSSVLICCVL 4338



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 23/83 (27%), Positives = 32/83 (38%), Gaps = 5/83 (6%)

Query: 1109 WPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRS 1168
            WP    ++ PSP    P  SP   S  +  P  + SP   T++   PT  P P   P  +
Sbjct: 1390 WPMDKCITTPSPPTTTP--SPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSP---PITT 1444

Query: 1169 WAASIPTILTHSALNILLLPSPT 1191
                 PT      ++    P PT
Sbjct: 1445 TTTPPPTTTPSPPISTTTTPPPT 1467


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 71/282 (25%), Positives = 115/282 (40%), Gaps = 30/282 (10%)

Query: 984  PPSPIG-GDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042
            P  P G  + +   ++ LQPP      P QP ++GA    +   +      Q+ S +  Q
Sbjct: 371  PVQPSGQSEYLQQHVAGLQPPS-----PAQPSSTGAAASPATAATLPVGTGQNASSVGAQ 425

Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPS-SPYTMVS 1101
              G   A+S PS A+         P   P+  G  + P      P  T+     P    +
Sbjct: 426  LMG---ASSQPSEAM--------APRTGPAQGG-QVAPCQPTGVPPATVGGVVQPCLGPA 473

Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPG----MSPANPSLHSPVPDASHSPRAGTSSQTMPTN 1157
             +G+  + P  PQ+ G  P + +PG    + P  P++ + VP A   P   T+S TMP N
Sbjct: 474  GAGQPQSVP-PPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVP-APSVPSVSTTSVTMP-N 530

Query: 1158 MPPP----RKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLERFLGS 1213
            +P P    ++L   +  +   +I+ H  L +       P  +P    S   +  +  +G 
Sbjct: 531  VPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQ 590

Query: 1214 VIMRRHLQRIIQQETLQLINSNEPGVIMFKTDALKCRVALSP 1255
            V   R     + Q  L LI  N+P V     D+L   + L+P
Sbjct: 591  VDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTP 632


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 56/204 (27%), Positives = 75/204 (36%), Gaps = 31/204 (15%)

Query: 985  PSPIGGDMMDSLISQLQPPPQQQPFP---KQPGTSGAYPLTSPPTSYHSTVNQSPSMMHT 1041
            P+P     +  +++Q  PP    P P   KQP    +Y   SPPT     V   P  +  
Sbjct: 786  PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP---PVPVPPPTLPK 842

Query: 1042 QSPGNLHAASSPSGALRAPS-----PASFVPTP-PPSSHGISIGPGASFASPHGTLDPSS 1095
            Q   +  A   PS     PS      + F P P PP+     + P  +  +P      S 
Sbjct: 843  QQ--SFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQ-----SP 895

Query: 1096 PYTMVSPSGRAGNWP-----------GSPQVSGPSPAARMPGMSPANPSLHSPVPDASHS 1144
            P     P  +  + P            S  V  P P + +P   P  P   SP PD S S
Sbjct: 896  PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGS 955

Query: 1145 PRAGTSSQTMPTNMPPPRKLPQRS 1168
            P   TS  + P    PP   PQR+
Sbjct: 956  PGKKTSKTSSPGGKKPP-PTPQRN 978



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 45/182 (24%), Positives = 64/182 (35%), Gaps = 29/182 (15%)

Query: 984  PPSPIGG--DMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHT 1041
            PPSP+     ++  + SQ  PPP                  +PP      +   P+ +  
Sbjct: 851  PPSPLSPVPSVVKQIASQFPPPP------------------TPPAMESQPLKPVPANVAP 892

Query: 1042 QSPGNLHAASS--PSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM 1099
            QSP  + A     PS ++  PSP  F P PP SS      P +   +P     P  P   
Sbjct: 893  QSPPAVKAKPKWQPS-SIPVPSP-DFPPPPPESSLVFPPPPPSPVPAP-----PPPPPPT 945

Query: 1100 VSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMP 1159
             SP+      PG       SP  + P  +P   S       A H      S  ++ +   
Sbjct: 946  ASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFT 1005

Query: 1160 PP 1161
            PP
Sbjct: 1006 PP 1007



 Score = 40.4 bits (93), Expect = 0.013
 Identities = 47/201 (23%), Positives = 70/201 (34%), Gaps = 41/201 (20%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            PPP   P P  PG++ A    +P        +  P  +      ++   + P+     P 
Sbjct: 710  PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI 769

Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPA 1121
            PA   P  PP        P  +  +P  T   +   T  +P               P+P 
Sbjct: 770  PAPLPPQAPPK-------PLVTIPAPTSTKTVAPVVTQAAP---------------PTPT 807

Query: 1122 ARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSA 1181
              +P      P+   P   AS+ P    S  T P  +PPP    Q+S+ A  P     S 
Sbjct: 808  PPVP------PAKKQPAFPASYIP---PSPPTPPVPVPPPTLPKQQSFCAKPPP----SP 854

Query: 1182 LNILLLPSPTPGLVPGLAGSY 1202
            L      SP P +V  +A  +
Sbjct: 855  L------SPVPSVVKQIASQF 869



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 38/153 (24%), Positives = 53/153 (34%), Gaps = 16/153 (10%)

Query: 1048 HAASSPSGALRAPSPASFVPTPP--------PSSHGISIGPGASFASPHGTLDPSSPYTM 1099
            + AS PS  L  P P    P PP        PS    S G  A     + T+  +     
Sbjct: 619  YTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTI--TRLQNA 676

Query: 1100 VSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMP 1159
               SG     P  P +   S   ++  + P N  +  P P           +Q  P    
Sbjct: 677  SQHSGALFKPPTPPVMQSQSVKPQI--LVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA 734

Query: 1160 PPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192
            P   LPQ  ++A  P +  H   +I  +  PTP
Sbjct: 735  P--SLPQ--FSAPPPPLKIHQVQHITQVAPPTP 763



 Score = 30.8 bits (68), Expect = 9.9
 Identities = 35/134 (26%), Positives = 53/134 (39%), Gaps = 8/134 (5%)

Query: 1032 VNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTL 1091
            +N   ++  T+S  +  + SS S  +++ S +S +P    S+H      G S   P G +
Sbjct: 511  MNYQEALKRTESAYDWTSLSSSS--IKSGSSSSSIPESQ-SNHSNQSDSGVSDTQPAGHV 567

Query: 1092 DPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSS 1151
               S  + V        W    Q+   S  ARM  M+    SL  P+          T+S
Sbjct: 568  RSQSIVSSVFSEA----WKRGTQLE-ESSKARMESMNRPYTSLVPPLSPQPKIVTPYTAS 622

Query: 1152 QTMPTNMPPPRKLP 1165
            Q  P   PPP   P
Sbjct: 623  QPSPPLPPPPPPPP 636


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 75/266 (28%), Positives = 104/266 (39%), Gaps = 49/266 (18%)

Query: 973  ARRRSVNEDDNPPSPIGGDMMDSLISQL---QPPPQQQPFPKQPGTSGAYPLTSPPTSYH 1029
            ARR +       PSP       +  +++   +P P  +P   +P T G     S   S H
Sbjct: 160  ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP---RPPTEGPRKSVSS-ASEH 215

Query: 1030 STVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHG 1089
            ST   SP+     S G         G L+ P+  S   +  P S     GP A   +P  
Sbjct: 216  STTEPSPAARRRPSAG---------GGLQRPASRSLSSSATPLSSPARSGPSAR-GTPRA 265

Query: 1090 TLDPSSPY---------TMVSPSGR-----AGNWPGSPQVSGPSPAARM----PGMSPAN 1131
               PS P            V+P  +      G    SP ++ PSP+A +    P   PA 
Sbjct: 266  PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-LATPSPSAALQSQAPPTLPAT 324

Query: 1132 P-------SLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTI-LTHSAL- 1182
            P        L +P+P A  SP A  S QT+P+  PP     Q + +   PT+  THS L 
Sbjct: 325  PHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS--PPATPPSQATTSLGSPTLQATHSFLP 382

Query: 1183 --NILLLPSPTPGLVPGLAGSYLCSP 1206
               +  L +P P   P LA   L +P
Sbjct: 383  SPPLSPLATPPPQAPPALALPPLQAP 408



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 52/215 (24%), Positives = 80/215 (37%), Gaps = 36/215 (16%)

Query: 985  PSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSP 1044
            P+ +   ++ +  S    PP Q PF   P +    P  +PP+    ++   P  +    P
Sbjct: 428  PNALAVHLLQAPFSPPPSPPVQAPF-SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486

Query: 1045 GNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSG 1104
                          A  P S   TPPP +      P    A P     P +P  + +P  
Sbjct: 487  --------------ASPPMSPSATPPPQAPPPLAAPPLQLAKP----PPQAPPALATP-- 526

Query: 1105 RAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPV-PDASHSPRA----GTSSQTMPTNMP 1159
                    P  + PSP A  PG +P +PS   P+ P A+  P+A          +P + P
Sbjct: 527  --------PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578

Query: 1160 --PPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192
              P  + P+R       T ++   L + L P P P
Sbjct: 579  ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 61/220 (27%), Positives = 78/220 (35%), Gaps = 17/220 (7%)

Query: 984  PPSPIGGDMMDSLISQLQPP-PQQQPFPKQPGTSGAYPLT-SPPTSYHSTVNQSPSMMHT 1041
            PP+        SL  QL  P P   P P  P +    P   + P S  +T   SP++  T
Sbjct: 318  PPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 377

Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVS 1101
             S       S P   L  P P +      P        P +   SP  T  P +P  +  
Sbjct: 378  HS----FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433

Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMP-- 1159
               +A   P SP    PSP  + P   PA+P +    P A+   +A  S    P  +P  
Sbjct: 434  HLLQA---PFSPP---PSPPVQAPFSPPASPPVS---PSATPPSQAPPSLAAPPLQVPPS 484

Query: 1160 PPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLA 1199
            PP   P    A   P      A   L L  P P   P LA
Sbjct: 485  PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 524



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 54/193 (27%), Positives = 77/193 (39%), Gaps = 22/193 (11%)

Query: 1004 PQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPA 1063
            P+    P QP   G   L  PP       + +P++    S  +  A  SPS AL++ +P 
Sbjct: 263  PRAPAHPSQPKPKGLQALR-PPQVTPPRKDAAPALGPLSS--SPLATPSPSAALQSQAPP 319

Query: 1064 SFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAAR 1123
            +   TP  SS    +      A P  +  PS   T+ SP       P +P    PS A  
Sbjct: 320  TLPATPHSSSLTCQLATPLPLAPPSPSAPPSL-QTLPSP-------PATP----PSQATT 367

Query: 1124 MPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAA------SIPTIL 1177
              G SP   + HS +P    SP A    Q  P    PP + P    A+      + P+  
Sbjct: 368  SLG-SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 426

Query: 1178 THSALNILLLPSP 1190
              +AL + LL +P
Sbjct: 427  APNALAVHLLQAP 439



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 104/430 (24%), Positives = 147/430 (34%), Gaps = 61/430 (14%)

Query: 1011 KQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP-------- 1062
            +  GTS   P + PP S      ++P   +T SPG + +    SG  R P P        
Sbjct: 81   RSAGTSSRNPASRPPASGRG--ERAPPAKNT-SPGPVSSPGRASGTTR-PGPLGQKGLRI 136

Query: 1063 ------ASFVPTPPPSSHGISIGPGASFASPH-GTLDPSSPYTMVSPSGRAGNWPGSPQV 1115
                  A    T  P    +S G     + P  GT  P+    M   S  AG   G P+ 
Sbjct: 137  SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA----MARRSRAAGTEVGLPRP 192

Query: 1116 SG---PSPAARMPGMSPANPSLHS---PVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSW 1169
            +    P P    P  S ++ S HS   P P A   P AG   Q      P  R L   + 
Sbjct: 193  APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR-----PASRSLSSSAT 247

Query: 1170 AASIPTILTHSALNILLLPS----PTPGLVPGLAGSYLCSPLERFLGSVIMRRHLQRIIQ 1225
              S P     SA      P+    P P  +  L    +  P  +     +       +  
Sbjct: 248  PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP-RKDAAPALGPLSSSPLAT 306

Query: 1226 QETLQLINSNEPGVIMFK--TDALKCRVALSPKTNQTLQLKVTPENAGQWKPDELQVLEK 1283
                  + S  P  +     + +L C++A          L + P +     P  LQ L  
Sbjct: 307  PSPSAALQSQAPPTLPATPHSSSLTCQLATP--------LPLAPPSPSA--PPSLQTLP- 355

Query: 1284 FFETRVAGPPFKANTLIAFTKLLGAPTHILRDCVHIMKLELFPDQATQ-LKWNVQFCLTI 1342
               +  A PP +A T +    L    TH       +  L   P QA   L          
Sbjct: 356  ---SPPATPPSQATTSLGSPTLQA--THSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410

Query: 1343 PPSAPPIAPPGTPAVVLKSKMLFFLQLTQKTSVPPQEPVSIIVPIIYDMASGTTQQADIP 1402
            PP++PP++P  TP+    + +   L L    S PP  PV    P     +   +  A  P
Sbjct: 411  PPASPPLSPLATPSPQAPNALAVHL-LQAPFSPPPSPPVQ--APFSPPASPPVSPSATPP 467

Query: 1403 RQQNSSVAAP 1412
             Q   S+AAP
Sbjct: 468  SQAPPSLAAP 477



 Score = 38.5 bits (88), Expect = 0.048
 Identities = 48/174 (27%), Positives = 64/174 (36%), Gaps = 12/174 (6%)

Query: 983  NPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042
            +PP+   G    S  + L   P   P P+ P    A  L  PP+   S   Q+P    T 
Sbjct: 533  SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT- 591

Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSP-----Y 1097
             PG   + S P   L A +P    P PPPS    S   G   A  H +   S+P     Y
Sbjct: 592  -PGPDTSVSGPRLTL-ALAPG---PPPPPSRSPSSTLSGPDLAG-HSSSATSTPEELRGY 645

Query: 1098 TMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSS 1151
                  G A + P   +++   PAA   G +P      +P       P  G  S
Sbjct: 646  DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 699



 Score = 37.7 bits (86), Expect = 0.081
 Identities = 54/224 (24%), Positives = 72/224 (32%), Gaps = 43/224 (19%)

Query: 1002 PPPQQQPF---------PKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAAS- 1051
            PPPQ  P          P  P +        PPT    T    P +    +PG     S 
Sbjct: 558  PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617

Query: 1052 SPSGALRAPSPA---SFVPTPPPSSHGISIGP-GASFASPHGTLD------------PSS 1095
            SPS  L  P  A   S   + P    G   GP G + ASP    +            P+ 
Sbjct: 618  SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 677

Query: 1096 PYTMVSPSGRAGNWPGSP------------QVSGPSPAARMPGMSPANPSLHSPVPDASH 1143
            P       G    WP +             +  GP  A   PG     PS  +    A+ 
Sbjct: 678  PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 737

Query: 1144 SPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLL 1187
               AG SS++     P   +L +    A   +++ H     LLL
Sbjct: 738  GAGAGASSRS-----PKQARLGELPLGALQASVVQHLLSRTLLL 776


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
            sapiens]
          Length = 1188

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 55/197 (27%), Positives = 71/197 (36%), Gaps = 29/197 (14%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP--LTSPPTSYHSTVNQSPSMMHT 1041
            PP P  G   D     +  PP   P P  P T+   P  L  PP    S     P ++  
Sbjct: 143  PPGPAPGPPQD-----ISEPPGGSPLPSPPSTAPPPPPLLLEPPPP-PSMAPPPPPVLEA 196

Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVS 1101
             SP   H  SSPS     P+P  F+P  PP +      P     +P     P +  T + 
Sbjct: 197  LSPP--HTLSSPS----IPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLF 250

Query: 1102 PSGRAGNWPGSPQVSGPSPAA--RMPGMSPANP--SLHSPVPDASHSPRAGTSSQTMPTN 1157
            P G    W     ++G    A    P  SPA P  S   P P+            T P +
Sbjct: 251  PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE---------PHLTFPRS 301

Query: 1158 MPPPRKLPQRSWAASIP 1174
               P   P R+  +SIP
Sbjct: 302  FKVPPPTPVRT--SSIP 316



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 51/192 (26%), Positives = 70/192 (36%), Gaps = 29/192 (15%)

Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVN-QSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            PP+    P +P  S   P   P  ++  +     P+ + T S     A  +P     A  
Sbjct: 276  PPRS---PAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332

Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM-----VSP---------SGRAG 1107
             A      PPS H   I P AS   P    +P  P  +      SP           RAG
Sbjct: 333  KAPSRLPLPPSFH---IRP-ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAG 388

Query: 1108 NWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHS--PRAG---TSSQTMPTNMPPPR 1162
              P +P +  P PA  +P  +P  P    P+P A  +  P AG   T   + P   P P 
Sbjct: 389  TPPPAPPL--PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446

Query: 1163 KLPQRSWAASIP 1174
                 + A+S P
Sbjct: 447  PPSPENTASSAP 458



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 44/192 (22%), Positives = 68/192 (35%), Gaps = 32/192 (16%)

Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062
            PP+  P P  P  +  +P T P     +T+  +  +  T  P      ++P  A   P+ 
Sbjct: 642  PPKATPEPAIPPKATLWPATPP----KATLGPATPLKATSGP------TTPLKATSGPAI 691

Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGS-----PQVSG 1117
            AS   T P ++  +        + P G  +  +   + +PS   G    S     P    
Sbjct: 692  ASTATTLPTTTSQLM---AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGA 748

Query: 1118 PSPAARMPGMSPAN---PSLHSPVPDASH-----------SPRAGTSSQTMPTNMPPPRK 1163
             S AA  P  SP     P L+ P    S              R G +    P  +  P  
Sbjct: 749  RSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPG 808

Query: 1164 LPQRSWAASIPT 1175
            LP +  A++ PT
Sbjct: 809  LPAKPPASAQPT 820


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
            sapiens]
          Length = 1188

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 55/197 (27%), Positives = 71/197 (36%), Gaps = 29/197 (14%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP--LTSPPTSYHSTVNQSPSMMHT 1041
            PP P  G   D     +  PP   P P  P T+   P  L  PP    S     P ++  
Sbjct: 143  PPGPAPGPPQD-----ISEPPGGSPLPSPPSTAPPPPPLLLEPPPP-PSMAPPPPPVLEA 196

Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVS 1101
             SP   H  SSPS     P+P  F+P  PP +      P     +P     P +  T + 
Sbjct: 197  LSPP--HTLSSPS----IPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLF 250

Query: 1102 PSGRAGNWPGSPQVSGPSPAA--RMPGMSPANP--SLHSPVPDASHSPRAGTSSQTMPTN 1157
            P G    W     ++G    A    P  SPA P  S   P P+            T P +
Sbjct: 251  PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE---------PHLTFPRS 301

Query: 1158 MPPPRKLPQRSWAASIP 1174
               P   P R+  +SIP
Sbjct: 302  FKVPPPTPVRT--SSIP 316



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 51/192 (26%), Positives = 70/192 (36%), Gaps = 29/192 (15%)

Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVN-QSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            PP+    P +P  S   P   P  ++  +     P+ + T S     A  +P     A  
Sbjct: 276  PPRS---PAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332

Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM-----VSP---------SGRAG 1107
             A      PPS H   I P AS   P    +P  P  +      SP           RAG
Sbjct: 333  KAPSRLPLPPSFH---IRP-ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAG 388

Query: 1108 NWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHS--PRAG---TSSQTMPTNMPPPR 1162
              P +P +  P PA  +P  +P  P    P+P A  +  P AG   T   + P   P P 
Sbjct: 389  TPPPAPPL--PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446

Query: 1163 KLPQRSWAASIP 1174
                 + A+S P
Sbjct: 447  PPSPENTASSAP 458



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 44/192 (22%), Positives = 68/192 (35%), Gaps = 32/192 (16%)

Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062
            PP+  P P  P  +  +P T P     +T+  +  +  T  P      ++P  A   P+ 
Sbjct: 642  PPKATPEPAIPPKATLWPATPP----KATLGPATPLKATSGP------TTPLKATSGPAI 691

Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGS-----PQVSG 1117
            AS   T P ++  +        + P G  +  +   + +PS   G    S     P    
Sbjct: 692  ASTATTLPTTTSQLM---AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGA 748

Query: 1118 PSPAARMPGMSPAN---PSLHSPVPDASH-----------SPRAGTSSQTMPTNMPPPRK 1163
             S AA  P  SP     P L+ P    S              R G +    P  +  P  
Sbjct: 749  RSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPG 808

Query: 1164 LPQRSWAASIPT 1175
            LP +  A++ PT
Sbjct: 809  LPAKPPASAQPT 820


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
          Length = 1188

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 55/197 (27%), Positives = 71/197 (36%), Gaps = 29/197 (14%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYP--LTSPPTSYHSTVNQSPSMMHT 1041
            PP P  G   D     +  PP   P P  P T+   P  L  PP    S     P ++  
Sbjct: 143  PPGPAPGPPQD-----ISEPPGGSPLPSPPSTAPPPPPLLLEPPPP-PSMAPPPPPVLEA 196

Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVS 1101
             SP   H  SSPS     P+P  F+P  PP +      P     +P     P +  T + 
Sbjct: 197  LSPP--HTLSSPS----IPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLF 250

Query: 1102 PSGRAGNWPGSPQVSGPSPAA--RMPGMSPANP--SLHSPVPDASHSPRAGTSSQTMPTN 1157
            P G    W     ++G    A    P  SPA P  S   P P+            T P +
Sbjct: 251  PPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE---------PHLTFPRS 301

Query: 1158 MPPPRKLPQRSWAASIP 1174
               P   P R+  +SIP
Sbjct: 302  FKVPPPTPVRT--SSIP 316



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 51/192 (26%), Positives = 70/192 (36%), Gaps = 29/192 (15%)

Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVN-QSPSMMHTQSPGNLHAASSPSGALRAPS 1061
            PP+    P +P  S   P   P  ++  +     P+ + T S     A  +P     A  
Sbjct: 276  PPRS---PAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332

Query: 1062 PASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTM-----VSP---------SGRAG 1107
             A      PPS H   I P AS   P    +P  P  +      SP           RAG
Sbjct: 333  KAPSRLPLPPSFH---IRP-ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAG 388

Query: 1108 NWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHS--PRAG---TSSQTMPTNMPPPR 1162
              P +P +  P PA  +P  +P  P    P+P A  +  P AG   T   + P   P P 
Sbjct: 389  TPPPAPPL--PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446

Query: 1163 KLPQRSWAASIP 1174
                 + A+S P
Sbjct: 447  PPSPENTASSAP 458



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 44/192 (22%), Positives = 68/192 (35%), Gaps = 32/192 (16%)

Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062
            PP+  P P  P  +  +P T P     +T+  +  +  T  P      ++P  A   P+ 
Sbjct: 642  PPKATPEPAIPPKATLWPATPP----KATLGPATPLKATSGP------TTPLKATSGPAI 691

Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGS-----PQVSG 1117
            AS   T P ++  +        + P G  +  +   + +PS   G    S     P    
Sbjct: 692  ASTATTLPTTTSQLM---AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGA 748

Query: 1118 PSPAARMPGMSPAN---PSLHSPVPDASH-----------SPRAGTSSQTMPTNMPPPRK 1163
             S AA  P  SP     P L+ P    S              R G +    P  +  P  
Sbjct: 749  RSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPG 808

Query: 1164 LPQRSWAASIPT 1175
            LP +  A++ PT
Sbjct: 809  LPAKPPASAQPT 820


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 70/220 (31%), Positives = 88/220 (40%), Gaps = 36/220 (16%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPF-PKQPGTSGAYPLTSPPTSYHSTV---NQS--PS 1037
            PP  +G             P QQQP    QPG   A P   PP   H      NQ   PS
Sbjct: 1003 PPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPG---AVPPGVPPPGPHGPSPFPNQQTPPS 1059

Query: 1038 MMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPY 1097
            MM    PG+ H    P  A  AP    F   PPP     SI        P G+L  S   
Sbjct: 1060 MMPGAVPGSGH----PGVAGNAPLGLPFGMPPPPPPPAPSI-------IPFGSLADSISI 1108

Query: 1098 TMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTN 1157
             + +P    G+    P   G  P   +P +S ANP LH  +P          ++ TMP++
Sbjct: 1109 NLPAPPNLHGHHHHLPFAPGTLPPPNLP-VSMANP-LHPNLP----------ATTTMPSS 1156

Query: 1158 MPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPG 1197
            +P    L   S AA  P I+  +A+   LLPS +P   PG
Sbjct: 1157 LPLGPGL--GSAAAQSPAIV--AAVQGNLLPSASPLPDPG 1192



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 34/116 (29%), Positives = 47/116 (40%), Gaps = 17/116 (14%)

Query: 1070 PPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQ---VSGPSPAARMPG 1126
            PP+ HG+++ P +   +P G+  P          G+AG+  G  Q      P P A  PG
Sbjct: 980  PPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPG 1039

Query: 1127 MSPANPSLHSP--------------VPDASHSPRAGTSSQTMPTNMPPPRKLPQRS 1168
            + P  P   SP              VP + H   AG +   +P  MPPP   P  S
Sbjct: 1040 VPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAGNAPLGLPFGMPPPPPPPAPS 1095


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 66/233 (28%), Positives = 86/233 (36%), Gaps = 38/233 (16%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPK-QPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042
            PPSP              PPP   P P  QP T  A   ++P  +      Q P   H+ 
Sbjct: 257  PPSP-------------HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSL 303

Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGIS-IGPGASFASPHGTLDPSSPYTMVS 1101
              G L         L+ P P      PP +S G + +G   + A PH +L   +     S
Sbjct: 304  QAGPL---------LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA-----S 349

Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPGMSP--ANPSLHSPVPDA-SHSPR-AGTSSQTMPTN 1157
             S      P   Q   P+P A MP + P    P    P P A  H P  +G S  +M  N
Sbjct: 350  QSALQSQQPPREQPLPPAPLA-MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 408

Query: 1158 MPPPRKL-PQRSWAASIPTILTHSALNILLLPSP---TPGLVPGLAGSYLCSP 1206
            +PPP  L P  S +   P       L ++    P   +P   PGL  S    P
Sbjct: 409  LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 461



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 64/215 (29%), Positives = 85/215 (39%), Gaps = 30/215 (13%)

Query: 999  QLQPPPQQQPFPKQPGTSGAYP----LTSP-PTSYHSTVNQSPSMMHTQSPGNLHAASSP 1053
            Q QPP  Q P    P  S A P    L +P PT   + V    S   +Q+P    A ++P
Sbjct: 181  QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 240

Query: 1054 --------SGALRAPSPASFVPTPPPSSH-------GISIGPGA-SFASP--HGTLDPSS 1095
                    + AL    P S  P P PS H       G +  P A S A P  HG   P  
Sbjct: 241  VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ-GPPG 299

Query: 1096 PYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP 1155
            P+++   +G     PG PQ  G  P A   G +P      SP     H+     +SQ+  
Sbjct: 300  PHSL--QAGPLLQHPGPPQPFGLPPQASQ-GQAPLGT---SPAAAYPHTSLQLPASQSAL 353

Query: 1156 TNMPPPRKLPQRSWAASIPTILTHSALNILLLPSP 1190
             +  PPR+ P      ++P I       I  LP+P
Sbjct: 354  QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 388



 Score = 38.9 bits (89), Expect = 0.036
 Identities = 39/142 (27%), Positives = 48/142 (33%), Gaps = 23/142 (16%)

Query: 1000 LQPPPQQQPFPKQPGTSGAY---------PLTSPPTSYHSTVNQSPSMMHTQSPGNLHAA 1050
            LQ  PQ QP P  P               P + PPT  H    Q P   H   PG     
Sbjct: 434  LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI 493

Query: 1051 SSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHG---TLDPSSPYTMVSPSGRAG 1107
            + P+     PS ++     PP+  G S  P  S A+  G       S P   V     A 
Sbjct: 494  TPPT----CPSTST-----PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEAL 544

Query: 1108 NWPGSPQVSGPSPAARMPGMSP 1129
            +    P+   P P  R P   P
Sbjct: 545  DDAEEPE--SPPPPPRSPSPEP 564


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 66/233 (28%), Positives = 86/233 (36%), Gaps = 38/233 (16%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPK-QPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042
            PPSP              PPP   P P  QP T  A   ++P  +      Q P   H+ 
Sbjct: 811  PPSP-------------HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSL 857

Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGIS-IGPGASFASPHGTLDPSSPYTMVS 1101
              G L         L+ P P      PP +S G + +G   + A PH +L   +     S
Sbjct: 858  QAGPL---------LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA-----S 903

Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPGMSP--ANPSLHSPVPDA-SHSPR-AGTSSQTMPTN 1157
             S      P   Q   P+P A MP + P    P    P P A  H P  +G S  +M  N
Sbjct: 904  QSALQSQQPPREQPLPPAPLA-MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962

Query: 1158 MPPPRKL-PQRSWAASIPTILTHSALNILLLPSP---TPGLVPGLAGSYLCSP 1206
            +PPP  L P  S +   P       L ++    P   +P   PGL  S    P
Sbjct: 963  LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 1015



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 64/215 (29%), Positives = 85/215 (39%), Gaps = 30/215 (13%)

Query: 999  QLQPPPQQQPFPKQPGTSGAYP----LTSP-PTSYHSTVNQSPSMMHTQSPGNLHAASSP 1053
            Q QPP  Q P    P  S A P    L +P PT   + V    S   +Q+P    A ++P
Sbjct: 735  QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 794

Query: 1054 --------SGALRAPSPASFVPTPPPSSH-------GISIGPGA-SFASP--HGTLDPSS 1095
                    + AL    P S  P P PS H       G +  P A S A P  HG   P  
Sbjct: 795  VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ-GPPG 853

Query: 1096 PYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP 1155
            P+++   +G     PG PQ  G  P A   G +P      SP     H+     +SQ+  
Sbjct: 854  PHSL--QAGPLLQHPGPPQPFGLPPQASQ-GQAPLGT---SPAAAYPHTSLQLPASQSAL 907

Query: 1156 TNMPPPRKLPQRSWAASIPTILTHSALNILLLPSP 1190
             +  PPR+ P      ++P I       I  LP+P
Sbjct: 908  QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 942



 Score = 38.9 bits (89), Expect = 0.036
 Identities = 39/142 (27%), Positives = 48/142 (33%), Gaps = 23/142 (16%)

Query: 1000 LQPPPQQQPFPKQPGTSGAY---------PLTSPPTSYHSTVNQSPSMMHTQSPGNLHAA 1050
            LQ  PQ QP P  P               P + PPT  H    Q P   H   PG     
Sbjct: 988  LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI 1047

Query: 1051 SSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHG---TLDPSSPYTMVSPSGRAG 1107
            + P+     PS ++     PP+  G S  P  S A+  G       S P   V     A 
Sbjct: 1048 TPPT----CPSTST-----PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEAL 1098

Query: 1108 NWPGSPQVSGPSPAARMPGMSP 1129
            +    P+   P P  R P   P
Sbjct: 1099 DDAEEPE--SPPPPPRSPSPEP 1118


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 66/233 (28%), Positives = 86/233 (36%), Gaps = 38/233 (16%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPK-QPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042
            PPSP              PPP   P P  QP T  A   ++P  +      Q P   H+ 
Sbjct: 811  PPSP-------------HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSL 857

Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGIS-IGPGASFASPHGTLDPSSPYTMVS 1101
              G L         L+ P P      PP +S G + +G   + A PH +L   +     S
Sbjct: 858  QAGPL---------LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA-----S 903

Query: 1102 PSGRAGNWPGSPQVSGPSPAARMPGMSP--ANPSLHSPVPDA-SHSPR-AGTSSQTMPTN 1157
             S      P   Q   P+P A MP + P    P    P P A  H P  +G S  +M  N
Sbjct: 904  QSALQSQQPPREQPLPPAPLA-MPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962

Query: 1158 MPPPRKL-PQRSWAASIPTILTHSALNILLLPSP---TPGLVPGLAGSYLCSP 1206
            +PPP  L P  S +   P       L ++    P   +P   PGL  S    P
Sbjct: 963  LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPP 1015



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 64/215 (29%), Positives = 85/215 (39%), Gaps = 30/215 (13%)

Query: 999  QLQPPPQQQPFPKQPGTSGAYP----LTSP-PTSYHSTVNQSPSMMHTQSPGNLHAASSP 1053
            Q QPP  Q P    P  S A P    L +P PT   + V    S   +Q+P    A ++P
Sbjct: 735  QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 794

Query: 1054 --------SGALRAPSPASFVPTPPPSSH-------GISIGPGA-SFASP--HGTLDPSS 1095
                    + AL    P S  P P PS H       G +  P A S A P  HG   P  
Sbjct: 795  VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ-GPPG 853

Query: 1096 PYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP 1155
            P+++   +G     PG PQ  G  P A   G +P      SP     H+     +SQ+  
Sbjct: 854  PHSL--QAGPLLQHPGPPQPFGLPPQASQ-GQAPLGT---SPAAAYPHTSLQLPASQSAL 907

Query: 1156 TNMPPPRKLPQRSWAASIPTILTHSALNILLLPSP 1190
             +  PPR+ P      ++P I       I  LP+P
Sbjct: 908  QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 942



 Score = 38.9 bits (89), Expect = 0.036
 Identities = 39/142 (27%), Positives = 48/142 (33%), Gaps = 23/142 (16%)

Query: 1000 LQPPPQQQPFPKQPGTSGAY---------PLTSPPTSYHSTVNQSPSMMHTQSPGNLHAA 1050
            LQ  PQ QP P  P               P + PPT  H    Q P   H   PG     
Sbjct: 988  LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI 1047

Query: 1051 SSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHG---TLDPSSPYTMVSPSGRAG 1107
            + P+     PS ++     PP+  G S  P  S A+  G       S P   V     A 
Sbjct: 1048 TPPT----CPSTST-----PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEAL 1098

Query: 1108 NWPGSPQVSGPSPAARMPGMSP 1129
            +    P+   P P  R P   P
Sbjct: 1099 DDAEEPE--SPPPPPRSPSPEP 1118


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
            sapiens]
          Length = 503

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 70/241 (29%), Positives = 96/241 (39%), Gaps = 32/241 (13%)

Query: 983  NPPSPIGGDMMDSLISQLQPP-PQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHT 1041
            +PPS  G   + S   +  PP PQ+   P      G+ P + PP      V  +P  + +
Sbjct: 142  SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPP-----VPSTPRPIQS 196

Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPP--SSHGISIGPGASFASPHGTLDPSSPYTM 1099
             SP N  +   P G  R PSP    PTPPP   + G ++G G+   SP  +  P S    
Sbjct: 197  -SPHNRGSPPVPGGP-RQPSPG---PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP 251

Query: 1100 VSPS-GRA--GNWPGSPQVSGPSPAARMPGMSPANPSLHSP-VPDASHSPRAGTSSQTMP 1155
            + P+  RA     P  P   G  P+     + P  P  + P VP    +PR   SSQ   
Sbjct: 252  LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS---TPRPSASSQA-- 306

Query: 1156 TNMPPPRKLPQRSWAASIPTILTHS-------ALNILLLPSPTPGLVPGLAGSYLCSPLE 1208
               PPP   P R     +P   + +         N+ L  S  P   PG +G     P E
Sbjct: 307  ---PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363

Query: 1209 R 1209
            R
Sbjct: 364  R 364



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 51/192 (26%), Positives = 71/192 (36%), Gaps = 30/192 (15%)

Query: 989  GGDMMDSLISQLQPPPQQQPFPKQPGTS--GAYPLTSPPT----SYHSTVNQSPSMMHTQ 1042
            GG +  S +S   P   + P P  P  +     P   PP     S H      P   + +
Sbjct: 232  GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK 291

Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFAS------PHGTLDPSSP 1096
             P  + +   PS + +AP P      PPPS  G    P +S  +      P   L  SS 
Sbjct: 292  PP--VPSTPRPSASSQAPPPP-----PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS 344

Query: 1097 YTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPT 1156
               +   GR+G  P  P    P P    PG S        P+P      R G++S+ +P 
Sbjct: 345  TPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS-------GPLPPPPPVSRNGSTSRALPA 397

Query: 1157 NMPPPRKLPQRS 1168
                  +LP RS
Sbjct: 398  T----PQLPSRS 405



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 50/183 (27%), Positives = 62/183 (33%), Gaps = 29/183 (15%)

Query: 976  RSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQ-----PFPKQPGTSGAYPLTSPPTSYHS 1030
            R++++   PP P  G+        + PPP Q      P   +P  S   P   PP S   
Sbjct: 258  RALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS--- 314

Query: 1031 TVNQSPSMMHTQSPGNLHAASSP-------SGALRAPSPASFVPTPPPSSHGISIGPGAS 1083
                 P  +   S GN      P       S     PSP    P PPP S      P   
Sbjct: 315  --RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE----RPPPP 368

Query: 1084 FASPHGTLDPSSPYTMVSPSGRAGN-WPGSPQ------VSGPSPAARMPGMSPANPSLHS 1136
               P G   P  P   VS +G      P +PQ      V  P    R P + P  PS  +
Sbjct: 369  VRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR-PPLPPDRPSAGA 427

Query: 1137 PVP 1139
            P P
Sbjct: 428  PPP 430



 Score = 40.4 bits (93), Expect = 0.013
 Identities = 37/134 (27%), Positives = 47/134 (35%), Gaps = 19/134 (14%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPK---QPGTSGAYPLTSPPTSYHSTVNQSPSMMH 1040
            PP P  G         L PPP ++P P     PG SG  P   P +   ST    P+   
Sbjct: 346  PPLPSPGRS-----GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ 400

Query: 1041 TQSPGNLHAA-SSPSGALRAPSPASFVPTPPPSSHGISIG----------PGASFASPHG 1089
              S   + +  S P   L    P++  P PPP S  I  G              +  P  
Sbjct: 401  LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPIS 460

Query: 1090 TLDPSSPYTMVSPS 1103
             L P  PY   + S
Sbjct: 461  DLPPPEPYVQTTKS 474


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
            sapiens]
          Length = 503

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 70/241 (29%), Positives = 96/241 (39%), Gaps = 32/241 (13%)

Query: 983  NPPSPIGGDMMDSLISQLQPP-PQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHT 1041
            +PPS  G   + S   +  PP PQ+   P      G+ P + PP      V  +P  + +
Sbjct: 142  SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPP-----VPSTPRPIQS 196

Query: 1042 QSPGNLHAASSPSGALRAPSPASFVPTPPP--SSHGISIGPGASFASPHGTLDPSSPYTM 1099
             SP N  +   P G  R PSP    PTPPP   + G ++G G+   SP  +  P S    
Sbjct: 197  -SPHNRGSPPVPGGP-RQPSPG---PTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP 251

Query: 1100 VSPS-GRA--GNWPGSPQVSGPSPAARMPGMSPANPSLHSP-VPDASHSPRAGTSSQTMP 1155
            + P+  RA     P  P   G  P+     + P  P  + P VP    +PR   SSQ   
Sbjct: 252  LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS---TPRPSASSQA-- 306

Query: 1156 TNMPPPRKLPQRSWAASIPTILTHS-------ALNILLLPSPTPGLVPGLAGSYLCSPLE 1208
               PPP   P R     +P   + +         N+ L  S  P   PG +G     P E
Sbjct: 307  ---PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363

Query: 1209 R 1209
            R
Sbjct: 364  R 364



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 51/192 (26%), Positives = 71/192 (36%), Gaps = 30/192 (15%)

Query: 989  GGDMMDSLISQLQPPPQQQPFPKQPGTS--GAYPLTSPPT----SYHSTVNQSPSMMHTQ 1042
            GG +  S +S   P   + P P  P  +     P   PP     S H      P   + +
Sbjct: 232  GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK 291

Query: 1043 SPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFAS------PHGTLDPSSP 1096
             P  + +   PS + +AP P      PPPS  G    P +S  +      P   L  SS 
Sbjct: 292  PP--VPSTPRPSASSQAPPPP-----PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSS 344

Query: 1097 YTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPT 1156
               +   GR+G  P  P    P P    PG S        P+P      R G++S+ +P 
Sbjct: 345  TPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS-------GPLPPPPPVSRNGSTSRALPA 397

Query: 1157 NMPPPRKLPQRS 1168
                  +LP RS
Sbjct: 398  T----PQLPSRS 405



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 50/183 (27%), Positives = 62/183 (33%), Gaps = 29/183 (15%)

Query: 976  RSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQ-----PFPKQPGTSGAYPLTSPPTSYHS 1030
            R++++   PP P  G+        + PPP Q      P   +P  S   P   PP S   
Sbjct: 258  RALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS--- 314

Query: 1031 TVNQSPSMMHTQSPGNLHAASSP-------SGALRAPSPASFVPTPPPSSHGISIGPGAS 1083
                 P  +   S GN      P       S     PSP    P PPP S      P   
Sbjct: 315  --RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE----RPPPP 368

Query: 1084 FASPHGTLDPSSPYTMVSPSGRAGN-WPGSPQ------VSGPSPAARMPGMSPANPSLHS 1136
               P G   P  P   VS +G      P +PQ      V  P    R P + P  PS  +
Sbjct: 369  VRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR-PPLPPDRPSAGA 427

Query: 1137 PVP 1139
            P P
Sbjct: 428  PPP 430



 Score = 40.4 bits (93), Expect = 0.013
 Identities = 37/134 (27%), Positives = 47/134 (35%), Gaps = 19/134 (14%)

Query: 984  PPSPIGGDMMDSLISQLQPPPQQQPFPK---QPGTSGAYPLTSPPTSYHSTVNQSPSMMH 1040
            PP P  G         L PPP ++P P     PG SG  P   P +   ST    P+   
Sbjct: 346  PPLPSPGRS-----GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ 400

Query: 1041 TQSPGNLHAA-SSPSGALRAPSPASFVPTPPPSSHGISIG----------PGASFASPHG 1089
              S   + +  S P   L    P++  P PPP S  I  G              +  P  
Sbjct: 401  LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPIS 460

Query: 1090 TLDPSSPYTMVSPS 1103
             L P  PY   + S
Sbjct: 461  DLPPPEPYVQTTKS 474


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 57/211 (27%), Positives = 81/211 (38%), Gaps = 20/211 (9%)

Query: 972  DARRRSVNEDDNPPSPIGGDMMDSLI---SQLQPPPQQQPFPKQPGTSGAYPLTSPPTSY 1028
            +A R S   ++ P SP+   +  S     S L PPP++ P    P +S   PL   P S 
Sbjct: 463  EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP 522

Query: 1029 HSTVNQSPSMMHTQSPGNLHAASSP--SGALRAPSPASFVPTPPPSSHGISIGPGASFAS 1086
                  SP++    SP    +  SP    +  +P P     +PPP +  +S  P  S  S
Sbjct: 523  PEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582

Query: 1087 PHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASH-SP 1145
            P     P SP     P   +  +P         P    P   P   S  SP P+AS  SP
Sbjct: 583  PPPEESPMSP-----PPEASRLFP---------PFEESPLSPPPEESPLSPPPEASRLSP 628

Query: 1146 RAGTSSQTMPTNMPPPRKLPQRSWAASIPTI 1176
                S  + P    P    P+ S  + +P +
Sbjct: 629  PPEDSPMSPPPEESPMSPPPEVSRLSPLPVV 659



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 72/278 (25%), Positives = 94/278 (33%), Gaps = 69/278 (24%)

Query: 983  NPPSPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQ 1042
            +PP  +       ++S+L PPP++ P    P  S   P + PP +  S ++  P    T 
Sbjct: 645  SPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEES---PTSPPPEA--SRLSPPPEDSPTS 699

Query: 1043 SPGNLHAASSP--SGALRAP---SPASFVPTPP---PSSHGISIGPGASFASPHGTLDPS 1094
             P     AS P     +  P   SP   +P  P   P S G  + P      PH +  P 
Sbjct: 700  PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE--EPHLSPRPE 757

Query: 1095 SPYTMVSPSGRAGNWPGSPQVSGP-----------SPAARMPGMSPANPSLH-------- 1135
             P+  +SP     +   SPQ   P           SP A  P +SP    LH        
Sbjct: 758  EPH--LSPQAEEPHL--SPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813

Query: 1136 -----------SPVPDASH----------SPRAGTSSQTMPTNMPP----PRKLPQRSWA 1170
                       SP P+ SH          SPR   S  +     PP    P K P+    
Sbjct: 814  HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQ 873

Query: 1171 ASIPTILTHSALNILLLPSPTPGLVPGLAGSYLCSPLE 1208
               P  L       L  P   P L P L    L  P E
Sbjct: 874  CPAPEELP------LFPPPGEPSLSPLLGEPALSEPGE 905



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 60/220 (27%), Positives = 78/220 (35%), Gaps = 25/220 (11%)

Query: 998  SQLQPPPQQQPFPKQPGTS------GAYPLTSPPTSYHST--VNQSP-SMMHTQSPGNLH 1048
            S L PPP++ P    P  S         P +  P + H +  + +SP S    +SP +  
Sbjct: 447  SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506

Query: 1049 AASSPSGALRAP--SPASFVPTPPPSSHGISIGPGASFASP---HGTLDPSSPYTMVSPS 1103
              SSP   L     SP    P  P     +S  P AS  SP      L P       SP 
Sbjct: 507  PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP 566

Query: 1104 GRAGNWPGSPQVSGPSPAARMPGMSPA----------NPSLHSPVPDASH-SPRAGTSSQ 1152
              A      P+ S  SP      MSP             S  SP P+ S  SP    S  
Sbjct: 567  PEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626

Query: 1153 TMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTP 1192
            + P    P    P+ S  +  P +   S L ++   SP P
Sbjct: 627  SPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPP 666



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 50/186 (26%), Positives = 67/186 (36%), Gaps = 17/186 (9%)

Query: 998  SQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASS-PSGA 1056
            S L PPP++ P    P  S   P   PP    S ++  P       P  +   S  P  +
Sbjct: 606  SPLSPPPEESPLSPPPEASRLSP---PPED--SPMSPPPEESPMSPPPEVSRLSPLPVVS 660

Query: 1057 LRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVS 1116
              +P P     +PPP     S  P AS  SP     P+SP    SP   A   P    +S
Sbjct: 661  RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP---ASPPPEDSLMS 717

Query: 1117 GP------SPAARMPGMSPANPSLH-SPVPDASH-SPRAGTSSQTMPTNMPPPRKLPQRS 1168
             P       P    P + P +   H SP P+  H SPR      +     P     P+  
Sbjct: 718  LPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEP 777

Query: 1169 WAASIP 1174
               ++P
Sbjct: 778  CLCAVP 783



 Score = 38.5 bits (88), Expect = 0.048
 Identities = 54/199 (27%), Positives = 73/199 (36%), Gaps = 32/199 (16%)

Query: 1010 PKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTP 1069
            P QPG  G+ P  + PT +  +   +P+ + T + G L              PA  VP P
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPT-TPAGLSTSADGFLKP------------PAGSVPGP 2153

Query: 1070 PPSSHGISIGPGASFASPHGTLDPSSPYTMVS--PSGRAGNWPGSPQVSGPSPAARMPGM 1127
                      PG  F      L P  P  + S  P G A  +P  P+    +P    P  
Sbjct: 2154 D--------SPGELFLK----LPPQVPAQVPSQDPFGLAPAYPLEPRFP-TAPPTYPPYP 2200

Query: 1128 SPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLL 1187
            SP       P+  AS  P AG   +   T    PR  P        P      +L+ L +
Sbjct: 2201 SPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRC---PSLDNLAV 2257

Query: 1188 PSPTPGLVPGLAGSYLCSP 1206
            P  +PG+  G A   L SP
Sbjct: 2258 PE-SPGVGGGKASEPLLSP 2275



 Score = 38.5 bits (88), Expect = 0.048
 Identities = 53/195 (27%), Positives = 65/195 (33%), Gaps = 46/195 (23%)

Query: 1001 QPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSP-SMMHTQSP-------GNLHAASS 1052
            QPP   +P P  P +  A P  S P+   S V  SP S   +QSP             S 
Sbjct: 2380 QPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP 2439

Query: 1053 PSGALRAPSPASFVPTPPPS----------------------------SHGISIGPGASF 1084
             +   ++P P S  P+ P S                            S G    P A  
Sbjct: 2440 VTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALP 2499

Query: 1085 ASPHGTLDPSSPYTMVSPSGRAGNWPGSPQ----VSGPSPAARMPGMSPANPSLHSPVPD 1140
            A P G L          PSG+  N+  SP     V  PSP       +   PSL  PVP 
Sbjct: 2500 AGPAGELHAK------VPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQ 2553

Query: 1141 ASHSPRAGTSSQTMP 1155
                P  G +S   P
Sbjct: 2554 PGLPPPHGINSHFGP 2568



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 44/163 (26%), Positives = 57/163 (34%), Gaps = 37/163 (22%)

Query: 1000 LQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059
            L PPP++ P    P  S     TSPP                           P  +  +
Sbjct: 440  LLPPPEESPLSPPPEESP----TSPP---------------------------PEASRLS 468

Query: 1060 PSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGS-PQVSGP 1118
            P P     +P P +  +S     S  SP     P SP    SP       P S P+ S P
Sbjct: 469  PPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPP 528

Query: 1119 SPAARMPGMSPANPS-LHSPVPDASHSPRAGTSSQTMPTNMPP 1160
            SPA   P   P   S L  P  ++  SP      + +PT+ PP
Sbjct: 529  SPALETPLSPPPEASPLSPPFEESPLSP----PPEELPTSPPP 567



 Score = 35.8 bits (81), Expect = 0.31
 Identities = 36/140 (25%), Positives = 50/140 (35%), Gaps = 13/140 (9%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTS-----PPTSYHS------TVNQSPSMMHTQSPGNLHAA 1050
            P P +  FP+  G     P        PP   +S      T+ +  S  +T + GN H +
Sbjct: 2531 PSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPS 2590

Query: 1051 SSPSGALRAPSPASF--VPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGN 1108
             SP G     +  S+   P  PPS        G+     HG    S   + V      G 
Sbjct: 2591 GSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGT 2650

Query: 1109 WPGSPQVSGPSPAARMPGMS 1128
              GS   +   P  + PGMS
Sbjct: 2651 GMGSSLATAELPGTQDPGMS 2670



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 39/152 (25%), Positives = 55/152 (36%), Gaps = 21/152 (13%)

Query: 992  MMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG--NLHA 1049
            +M   + Q Q   Q  P+ ++PGT      TSP         Q       Q+     L A
Sbjct: 4226 LMQRQLQQSQAVRQTPPY-QEPGTQ-----TSPLQGLLGCQPQLGGFPGPQTGPLQELGA 4279

Query: 1050 ASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGR---- 1105
               P G  R P+P   + T P       +GP      P    +P  P  + SPS +    
Sbjct: 4280 GPRPQGPPRLPAPPGALSTGPV------LGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTE 4333

Query: 1106 ---AGNWPGSPQVSGPSPAARMPGMSPANPSL 1134
                   PG+P+  GP+       +SPA   L
Sbjct: 4334 AQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQL 4365



 Score = 31.6 bits (70), Expect = 5.8
 Identities = 45/177 (25%), Positives = 66/177 (37%), Gaps = 26/177 (14%)

Query: 996  LISQLQPPPQQQPFPKQPGTSGAYP----LTSPPTSYHSTVNQSPS-------MMHTQSP 1044
            L+S   P   +  FP+ P  +G  P       P         +SP              P
Sbjct: 4806 LLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLP 4865

Query: 1045 G-NLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPS 1103
            G  L +       L+  SPA   PT    ++ +S       ++P    +PS P + ++PS
Sbjct: 4866 GYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPE-EPSPPPSPLAPS 4924

Query: 1104 GRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPP 1160
                  P SP      P   +P    A P + SP+P AS SP    S++  P   PP
Sbjct: 4925 ------PASPPTE---PLVELPTEPLAEPPVPSPLPLAS-SPE---SARPKPRARPP 4968


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 51/184 (27%), Positives = 70/184 (38%), Gaps = 26/184 (14%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTS-------PPTSYHSTVNQSPSMMHTQSPGNLHAASSPS 1054
            PPP   P P+ P ++   P  S        PT YH+ +    S M    PG    A  P 
Sbjct: 161  PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPG----APPPH 216

Query: 1055 GALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYT--MVSPSGRAGNWPGS 1112
              L        +  PP    G   G  +S   P+G      P T   VS SG +G  P  
Sbjct: 217  PQLYPGGTGGVLSGPPMGPKG--GGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK 274

Query: 1113 P--------QVSGPSPAARMPGMSP--ANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPR 1162
            P         +    P A  P ++P    P    P+ +AS SP  G  +Q +P ++P P 
Sbjct: 275  PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP-PGLGAQPLPGHLPSPH 333

Query: 1163 KLPQ 1166
             + Q
Sbjct: 334  AMGQ 337



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 56/209 (26%), Positives = 76/209 (36%), Gaps = 31/209 (14%)

Query: 984  PPSPIGGDMMDSLIS----QLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMM 1039
            P  P GG    S+      +  PPP         G SGA P T PPT+            
Sbjct: 232  PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPP-TKPPTT------------ 278

Query: 1040 HTQSPGNLHAASSPSGALRAPSPASFVPTPP---PSSHGISIGPGASFASPHGTLDPSSP 1096
                 GNL +A  P+     P     +P PP   P ++  +  PG       G L   SP
Sbjct: 279  -PVGGGNLPSAPPPA---NFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHL--PSP 332

Query: 1097 YTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPA-NPSLHSPVPDASHSPRAGTSSQTMP 1155
            + M    G     P       PSP +  P  S A  P +  P   +S S  A +SS +  
Sbjct: 333  HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSS 392

Query: 1156 TN----MPPPRKLPQRSWAASIPTILTHS 1180
            ++     P  + LP    +   PT L+ S
Sbjct: 393  SSSASPFPASQALPSYPHSFPPPTSLSVS 421



 Score = 38.1 bits (87), Expect = 0.062
 Identities = 49/199 (24%), Positives = 64/199 (32%), Gaps = 39/199 (19%)

Query: 1004 PQQQPFPKQPGTSGAYPLTSPPTSYHS---------TVNQSPSMMHTQSPGN-------- 1046
            P   P P Q      YP    PT   S         TV  SP+   T SP          
Sbjct: 584  PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA 643

Query: 1047 ----LHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSP 1102
                 +  ++P G  +  SP SF    PP   G S   G       GT  P SP      
Sbjct: 644  PSPGAYKTATPPG-YKPGSPPSFRTGTPPGYRGTSPPAGP------GTFKPGSPTV---- 692

Query: 1103 SGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPR 1162
                   PG    +GPS    +P   PA P+   P+             +T  + +PP R
Sbjct: 693  ------GPGPLPPAGPSGLPSLP-PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPAR 745

Query: 1163 KLPQRSWAASIPTILTHSA 1181
                      +P+  + SA
Sbjct: 746  SPSPPPKVVDVPSHASQSA 764



 Score = 38.1 bits (87), Expect = 0.062
 Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 32/146 (21%)

Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062
            PP   P+ K+  + GAY   +PP         SP    T +P      S P+G      P
Sbjct: 633  PPGPPPYGKRAPSPGAYKTATPP----GYKPGSPPSFRTGTPPGYRGTSPPAG------P 682

Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAA 1122
             +F P  P      ++GP        G L P+ P  + S        P +   SGP  +A
Sbjct: 683  GTFKPGSP------TVGP--------GPLPPAGPSGLPSLPP-----PPAAPASGPPLSA 723

Query: 1123 RMPGMSPAN--PSLHSPVPDA-SHSP 1145
                  PA    +  SPVP A S SP
Sbjct: 724  TQIKQEPAEEYETPESPVPPARSPSP 749



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 48/186 (25%), Positives = 69/186 (37%), Gaps = 18/186 (9%)

Query: 1001 QPPPQQQPFPKQPGTSGAYPLTSPP-TSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059
            Q PP   P+ +    S A+P   PP T   ST +   S  H                 + 
Sbjct: 440  QGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499

Query: 1060 PSPASFVPTPPPSSHGISIGPGASFASP--HGTLDPSSPYTMVSPSGRAGNWPGSPQVSG 1117
                     PPP        PGA F  P   G+   + PY M    G    +P  P    
Sbjct: 500  QQQHHGNSGPPP--------PGA-FPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP-AHL 549

Query: 1118 PSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRS--WAASIPT 1175
            P P +++   S A P  + P   +S +  + TS  + P + P P + PQ +      +PT
Sbjct: 550  PPPHSQV-SYSQAGP--NGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPT 606

Query: 1176 ILTHSA 1181
            + T SA
Sbjct: 607  VTTSSA 612


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 51/184 (27%), Positives = 70/184 (38%), Gaps = 26/184 (14%)

Query: 1002 PPPQQQPFPKQPGTSGAYPLTS-------PPTSYHSTVNQSPSMMHTQSPGNLHAASSPS 1054
            PPP   P P+ P ++   P  S        PT YH+ +    S M    PG    A  P 
Sbjct: 161  PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPG----APPPH 216

Query: 1055 GALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYT--MVSPSGRAGNWPGS 1112
              L        +  PP    G   G  +S   P+G      P T   VS SG +G  P  
Sbjct: 217  PQLYPGGTGGVLSGPPMGPKG--GGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK 274

Query: 1113 P--------QVSGPSPAARMPGMSP--ANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPR 1162
            P         +    P A  P ++P    P    P+ +AS SP  G  +Q +P ++P P 
Sbjct: 275  PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP-PGLGAQPLPGHLPSPH 333

Query: 1163 KLPQ 1166
             + Q
Sbjct: 334  AMGQ 337



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 56/209 (26%), Positives = 76/209 (36%), Gaps = 31/209 (14%)

Query: 984  PPSPIGGDMMDSLIS----QLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMM 1039
            P  P GG    S+      +  PPP         G SGA P T PPT+            
Sbjct: 232  PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPP-TKPPTT------------ 278

Query: 1040 HTQSPGNLHAASSPSGALRAPSPASFVPTPP---PSSHGISIGPGASFASPHGTLDPSSP 1096
                 GNL +A  P+     P     +P PP   P ++  +  PG       G L   SP
Sbjct: 279  -PVGGGNLPSAPPPA---NFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHL--PSP 332

Query: 1097 YTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPA-NPSLHSPVPDASHSPRAGTSSQTMP 1155
            + M    G     P       PSP +  P  S A  P +  P   +S S  A +SS +  
Sbjct: 333  HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSS 392

Query: 1156 TN----MPPPRKLPQRSWAASIPTILTHS 1180
            ++     P  + LP    +   PT L+ S
Sbjct: 393  SSSASPFPASQALPSYPHSFPPPTSLSVS 421



 Score = 38.1 bits (87), Expect = 0.062
 Identities = 49/199 (24%), Positives = 64/199 (32%), Gaps = 39/199 (19%)

Query: 1004 PQQQPFPKQPGTSGAYPLTSPPTSYHS---------TVNQSPSMMHTQSPGN-------- 1046
            P   P P Q      YP    PT   S         TV  SP+   T SP          
Sbjct: 584  PCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA 643

Query: 1047 ----LHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSP 1102
                 +  ++P G  +  SP SF    PP   G S   G       GT  P SP      
Sbjct: 644  PSPGAYKTATPPG-YKPGSPPSFRTGTPPGYRGTSPPAGP------GTFKPGSPTV---- 692

Query: 1103 SGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPR 1162
                   PG    +GPS    +P   PA P+   P+             +T  + +PP R
Sbjct: 693  ------GPGPLPPAGPSGLPSLP-PPPAAPASGPPLSATQIKQEPAEEYETPESPVPPAR 745

Query: 1163 KLPQRSWAASIPTILTHSA 1181
                      +P+  + SA
Sbjct: 746  SPSPPPKVVDVPSHASQSA 764



 Score = 38.1 bits (87), Expect = 0.062
 Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 32/146 (21%)

Query: 1003 PPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP 1062
            PP   P+ K+  + GAY   +PP         SP    T +P      S P+G      P
Sbjct: 633  PPGPPPYGKRAPSPGAYKTATPP----GYKPGSPPSFRTGTPPGYRGTSPPAG------P 682

Query: 1063 ASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAA 1122
             +F P  P      ++GP        G L P+ P  + S        P +   SGP  +A
Sbjct: 683  GTFKPGSP------TVGP--------GPLPPAGPSGLPSLPP-----PPAAPASGPPLSA 723

Query: 1123 RMPGMSPAN--PSLHSPVPDA-SHSP 1145
                  PA    +  SPVP A S SP
Sbjct: 724  TQIKQEPAEEYETPESPVPPARSPSP 749



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 48/186 (25%), Positives = 69/186 (37%), Gaps = 18/186 (9%)

Query: 1001 QPPPQQQPFPKQPGTSGAYPLTSPP-TSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRA 1059
            Q PP   P+ +    S A+P   PP T   ST +   S  H                 + 
Sbjct: 440  QGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499

Query: 1060 PSPASFVPTPPPSSHGISIGPGASFASP--HGTLDPSSPYTMVSPSGRAGNWPGSPQVSG 1117
                     PPP        PGA F  P   G+   + PY M    G    +P  P    
Sbjct: 500  QQQHHGNSGPPP--------PGA-FPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP-AHL 549

Query: 1118 PSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRS--WAASIPT 1175
            P P +++   S A P  + P   +S +  + TS  + P + P P + PQ +      +PT
Sbjct: 550  PPPHSQV-SYSQAGP--NGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPT 606

Query: 1176 ILTHSA 1181
            + T SA
Sbjct: 607  VTTSSA 612


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 51/192 (26%), Positives = 79/192 (41%), Gaps = 19/192 (9%)

Query: 1023 SPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSP-ASFVPTPPPSSHGISIGPG 1081
            +P  +  +T    P+     +  +  AAS P     A +  AS   T P SS   S  P 
Sbjct: 305  APVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADSPRPQ 364

Query: 1082 ASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDA 1141
            AS  SP           + + S  A +   S   + P+P  R+   +   PS++ PVP +
Sbjct: 365  ASSYSP----------AVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPAS 414

Query: 1142 SHSPRAGTS-SQTMPTNMPPPRKLPQRSWAASIPTILTHSALNILLLPSPTPGLVPGLAG 1200
            ++SP  G + S T  T  P P   P  + A +   + T++       PSP P   P  A 
Sbjct: 415  TYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYT-------PSPAPAYTPSPAP 467

Query: 1201 SYLCSPLERFLG 1212
            +Y  +P   + G
Sbjct: 468  NYNPAPSVAYSG 479



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 53/238 (22%), Positives = 79/238 (33%), Gaps = 50/238 (21%)

Query: 991  DMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG----N 1046
            D   SL++   P P+ +  P  PGT    P  SP  S  S  +   S+     PG    +
Sbjct: 112  DTNGSLVAP-SPSPEARASPGTPGTPELRPTFSPAFSRPSAFS---SLAEASDPGPPRAS 167

Query: 1047 LHAASSPSGALRAPSPASFVPTPPPSSHGISIG--------------------------- 1079
            L A +SP GA     P +   +  P  +   IG                           
Sbjct: 168  LRAKTSPEGARDLLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGL 227

Query: 1080 PGASFASPHGTLDPSSP-YTMV-----SPSGRAGNW---PGSPQVSGPSPAARMPG---- 1126
            PG S       +D +SP Y  V      P   A  W     + Q       A+M G    
Sbjct: 228  PGGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFM 287

Query: 1127 MSPANPSLHSPVPDASHSPRAGTSSQT--MPTNMPPPRKLPQRSWAASIPTILTHSAL 1182
              P   +L        H+P   + + T  +P +  PP      + +  + T   H+A+
Sbjct: 288  QDPDEEALRRSSTPIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAI 345



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 43/184 (23%), Positives = 71/184 (38%), Gaps = 20/184 (10%)

Query: 955  PAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGGDMMDSLISQLQPPPQQQPFPKQPG 1014
            P P   ++      S+  A   S +E    P+P    +  + I         +P   QP 
Sbjct: 361  PRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASI---------RPSVYQPV 411

Query: 1015 TSGAYPLTSPPTSYHST-VNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSS 1073
             +  Y   SP  +Y  T    SP+  +T SP   +  S       +P+PA + P+P P  
Sbjct: 412  PASTYS-PSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPA-YTPSPAP-- 467

Query: 1074 HGISIGPGASFASPHGTLDPSSPYTMVSPSGRAGNW-PG--SPQVSGPSPAARMPGMSPA 1130
               +  P  S A   G  +P+S    V+    +  + PG  +  +S  +     P  +PA
Sbjct: 468  ---NYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPA 524

Query: 1131 NPSL 1134
             P +
Sbjct: 525  GPQV 528


>gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transferase 4
            [Homo sapiens]
          Length = 1039

 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 59/202 (29%), Positives = 75/202 (37%), Gaps = 32/202 (15%)

Query: 968  DSNQDARRRS---VNEDDNPPSPIGGDMMDSLISQLQPPPQ---QQPFPKQPGTSGAYPL 1021
            D   + +RR+   +N DD       G+++DSL      PP+   Q P P  P   GA   
Sbjct: 416  DEEDEVQRRAFLFLNPDDFLDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGA--T 473

Query: 1022 TSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPG 1081
             +PPT        +P      S     A   P    RAP P   V  PPP  +   + PG
Sbjct: 474  LAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPG 533

Query: 1082 ASFASPHGTLDPSSPYTMVSPSGRAGNWPGSPQV-SGPSPAARMPGMSPANPSLHSPVPD 1140
               ASP             +P+ RA  WP  P V   P P  R+   +P       P P 
Sbjct: 534  QR-ASPR------------APAPRA-PWPPFPGVFLHPRPLPRVQLRAP-------PRPP 572

Query: 1141 ASHSPRAGTSSQTMPTNMPPPR 1162
              H  R G    T P   PP R
Sbjct: 573  RPHGRRTGGPQATQP--RPPAR 592


>gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 490

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 54/211 (25%), Positives = 88/211 (41%), Gaps = 18/211 (8%)

Query: 992  MMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAAS 1051
            ++  L+S +  PP   P       S    ++SPP+   S ++  PS++          + 
Sbjct: 106  LVSPLLSGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSLL----------SG 155

Query: 1052 SPSGALRAPSPASFVPTPPPSSHGISIG---PGASFASPHGTLDPSSPYTMVSPSGRAGN 1108
             PS     PSP S VP+PP     +  G   P +   SP   + PS P  +   S     
Sbjct: 156  VPSPPSDVPSPPSDVPSPPSDVPSLLSGVPSPPSDVPSPPSDV-PSPPSDVPLLSDVPSP 214

Query: 1109 WPGSPQVSG-PSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQR 1167
                P +S  PSP + +P +    PSL       S  P   +   + P+++ PP  +P  
Sbjct: 215  PSDVPLLSDVPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSPPSDISPPSDVP-- 272

Query: 1168 SWAASIPTILTHSALNILLLPSPTPGLVPGL 1198
            S  + +P++ +     +  +PSP P  VP L
Sbjct: 273  SLLSDVPSLPSDVPSLLSGVPSP-PSDVPSL 302



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 49/189 (25%), Positives = 74/189 (39%), Gaps = 34/189 (17%)

Query: 983  NPPSPIGGDMMDSLISQLQPPPQQQPFPKQ--PGTSGAYPLTSPPTSYHSTVNQSPSMMH 1040
            +PPS +      SL+S +  PP   P P    P  SG   + SPP+   S  +  PS   
Sbjct: 294  SPPSDV-----PSLLSDVPSPPSDVPSPPSDIPLLSG---VPSPPSDVPSPPSDVPS--- 342

Query: 1041 TQSPGNLHAASSPSGALRAPSPASFVPTPPPSSHGISIGPGASFASPHGTLDPSSPYTMV 1100
               P ++   S     L      S VP+PP     + +       SPH  L   S Y++V
Sbjct: 343  --PPSDVPLLSGVPSPLSDVPLLSGVPSPPSDVPSLLM-------SPHRLL--MSHYSLV 391

Query: 1101 SPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMPTNMPP 1160
            SP           ++  PS  + +P +    PS  S VP         +   ++P+ +P 
Sbjct: 392  SPH----------RLDVPSLLSDVPSLLSGVPSSPSGVPSLPSGVPILSGVPSLPSGVPS 441

Query: 1161 PRKLPQRSW 1169
            P  +P   W
Sbjct: 442  PSGVPITLW 450


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,028,603
Number of Sequences: 37866
Number of extensions: 3421292
Number of successful extensions: 35631
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 1262
Number of HSP's that attempted gapping in prelim test: 24687
Number of HSP's gapped (non-prelim): 11345
length of query: 1454
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1339
effective length of database: 13,892,928
effective search space: 18602630592
effective search space used: 18602630592
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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