Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 28416902
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28416902 interleukin 1 receptor-like 2 precursor [Homo
sapiens]
(575 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28416902 interleukin 1 receptor-like 2 precursor [Homo sapiens] 1187 0.0
gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens] 385 e-107
gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [H... 206 5e-53
gi|11225607 interleukin 1 receptor accessory protein-like 2 [Hom... 166 4e-41
gi|7657232 interleukin 1 receptor accessory protein-like 1 precu... 165 1e-40
gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens] 164 2e-40
gi|4504661 interleukin 1 receptor accessory protein isoform 1 [H... 156 4e-38
gi|4504657 interleukin 18 receptor accessory protein precursor [... 119 8e-27
gi|27894334 interleukin 1 receptor, type II precursor [Homo sapi... 103 3e-22
gi|4758598 interleukin 1 receptor, type II precursor [Homo sapiens] 103 3e-22
gi|27894328 interleukin 1 receptor-like 1 isoform 2 precursor [H... 84 4e-16
gi|205277451 single Ig IL-1R-related molecule [Homo sapiens] 69 1e-11
gi|205277449 single Ig IL-1R-related molecule [Homo sapiens] 69 1e-11
gi|205277445 single Ig IL-1R-related molecule [Homo sapiens] 69 1e-11
gi|19882209 interleukin 1 receptor accessory protein isoform 2 [... 66 1e-10
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 49 1e-05
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 49 1e-05
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 45 2e-04
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 45 2e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 44 4e-04
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 44 5e-04
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 44 5e-04
gi|7657361 contactin 6 [Homo sapiens] 43 9e-04
gi|38683840 CD96 antigen isoform 1 precursor [Homo sapiens] 42 0.001
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 42 0.002
gi|75709184 contactin 3 [Homo sapiens] 41 0.003
gi|144226847 obscurin-like 1 [Homo sapiens] 40 0.006
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 40 0.006
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 40 0.006
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 39 0.010
>gi|28416902 interleukin 1 receptor-like 2 precursor [Homo sapiens]
Length = 575
Score = 1187 bits (3071), Expect = 0.0
Identities = 575/575 (100%), Positives = 575/575 (100%)
Query: 1 MWSLLLCGLSIALPLSVTADGCKDIFMKNEILSASQPFAFNCTFPPITSGEVSVTWYKNS 60
MWSLLLCGLSIALPLSVTADGCKDIFMKNEILSASQPFAFNCTFPPITSGEVSVTWYKNS
Sbjct: 1 MWSLLLCGLSIALPLSVTADGCKDIFMKNEILSASQPFAFNCTFPPITSGEVSVTWYKNS 60
Query: 61 SKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDT 120
SKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDT
Sbjct: 61 SKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDT 120
Query: 121 SIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETRL 180
SIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETRL
Sbjct: 121 SIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETRL 180
Query: 181 LVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQ 240
LVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQ
Sbjct: 181 LVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQ 240
Query: 241 LGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYTVNI 300
LGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYTVNI
Sbjct: 241 LGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYTVNI 300
Query: 301 TFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFRAYLIGGLIALVAVAVSVVYIYNIFK 360
TFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFRAYLIGGLIALVAVAVSVVYIYNIFK
Sbjct: 301 TFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFRAYLIGGLIALVAVAVSVVYIYNIFK 360
Query: 361 IDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQRHAVDALVLNILPEVLERQCGYK 420
IDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQRHAVDALVLNILPEVLERQCGYK
Sbjct: 361 IDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQRHAVDALVLNILPEVLERQCGYK 420
Query: 421 LFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESLGFGLLKNLSEEQIAVYSALIQDG 480
LFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESLGFGLLKNLSEEQIAVYSALIQDG
Sbjct: 421 LFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESLGFGLLKNLSEEQIAVYSALIQDG 480
Query: 481 MKVILIELEKIEDYTVMPESIQYIKQKHGAIRWHGDFTEQSQCMKTKFWKTVRYHMPPRR 540
MKVILIELEKIEDYTVMPESIQYIKQKHGAIRWHGDFTEQSQCMKTKFWKTVRYHMPPRR
Sbjct: 481 MKVILIELEKIEDYTVMPESIQYIKQKHGAIRWHGDFTEQSQCMKTKFWKTVRYHMPPRR 540
Query: 541 CRPFPPVQLLQHTPCYRTAGPELGSRRKKCTLTTG 575
CRPFPPVQLLQHTPCYRTAGPELGSRRKKCTLTTG
Sbjct: 541 CRPFPPVQLLQHTPCYRTAGPELGSRRKKCTLTTG 575
>gi|4504659 interleukin 1 receptor, type I precursor [Homo sapiens]
Length = 569
Score = 385 bits (989), Expect = e-107
Identities = 232/562 (41%), Positives = 325/562 (57%), Gaps = 32/562 (5%)
Query: 5 LLCGLSIALPLSVTADGCKDIFMKNEILSASQPFAFN-CTFPPITSGEVSVTWYKNSSKI 63
L+C +++ + S+ AD CK+ K ++S++ C P + ++TWYK+ SK
Sbjct: 7 LICFIALLIS-SLEADKCKEREEKIILVSSANEIDVRPCPLNP-NEHKGTITWYKDDSKT 64
Query: 64 PVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIG 123
PVS SRIHQ + + F+P + DSG Y CV++ C RI ++ E
Sbjct: 65 PVSTEQASRIHQHKEKLWFVPAKVEDSGHYYCVVRNSSYCLRIKISAKFVENE------- 117
Query: 124 GLPNLSDE----YKQILHLGKDDSLTC-HLHFPKS--CVLGPIKWYKDCNEIKGER--FT 174
PNL +KQ L + D L C ++ F K+ L ++WYKDC + + F+
Sbjct: 118 --PNLCYNAQAIFKQKLPVAGDGGLVCPYMEFFKNENNELPKLQWYKDCKPLLLDNIHFS 175
Query: 175 VLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKN 234
++ RL+V NV+ + RGNY C A T+ GKQY + I E + P I+ P N
Sbjct: 176 GVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFITLEENK--PTRPVIVSPAN 233
Query: 235 HSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHN 294
++EV LG+ + + CNVT +++ W+ N +++D+ VE + R
Sbjct: 234 ETMEVDLGSQIQLICNVTGQL--SDIAYWKWNGSVIDEDDPVLGEDYYSVENPANKRRST 291
Query: 295 LYTVNITFLEVKMEDYGLPFMCHA----GVSTAYIILQLPAPDFRAYLIGGLIALVAVAV 350
L TV + E++ Y PF C A G+ AYI L P +F+ ++IG + L + V
Sbjct: 292 LITV-LNISEIESRFYKHPFTCFAKNTHGIDAAYIQLIYPVTNFQKHMIGICVTLTVIIV 350
Query: 351 SVVYIYNIFKIDIVLWYRSAFHSTETIV--DGKLYDAYVLYPKPHKESQRHAVDALVLNI 408
V+IY IFKIDIVLWYR + + I DGK YDAY+LYPK E D V +
Sbjct: 351 CSVFIYKIFKIDIVLWYRDSCYDFLPIKASDGKTYDAYILYPKTVGEGSTSDCDIFVFKV 410
Query: 409 LPEVLERQCGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESLGFGLLKNLSEE 468
LPEVLE+QCGYKLFI+GRD++ G+ + VI+ENVK RRLI+I+V E+ GF L SEE
Sbjct: 411 LPEVLEKQCGYKLFIYGRDDYVGEDIVEVINENVKKSRRLIIILVRETSGFSWLGGSSEE 470
Query: 469 QIAVYSALIQDGMKVILIELEKIEDYTVMPESIQYIKQKHGAIRWHGDFTEQSQCMKTKF 528
QIA+Y+AL+QDG+KV+L+ELEKI+DY MPESI++IKQKHGAIRW GDFT+ Q KT+F
Sbjct: 471 QIAMYNALVQDGIKVVLLELEKIQDYEKMPESIKFIKQKHGAIRWSGDFTQGPQSAKTRF 530
Query: 529 WKTVRYHMPPRRCRPFPPVQLL 550
WK VRYHMP +R P QLL
Sbjct: 531 WKNVRYHMPVQRRSPSSKHQLL 552
>gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [Homo
sapiens]
Length = 556
Score = 206 bits (524), Expect = 5e-53
Identities = 149/520 (28%), Positives = 255/520 (49%), Gaps = 38/520 (7%)
Query: 53 SVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTV 112
+V WY + + + ++R+ + FLP DSG+Y C+++ + N+T+
Sbjct: 45 TVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTI 104
Query: 113 FEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGER 172
++K S +P+ Y + K+ + C + P++W+K+C ++G R
Sbjct: 105 YKKQ----SDCNVPDYL-MYSTVSGSEKNSKIYCPTIDLYNWT-APLEWFKNCQALQGSR 158
Query: 173 FTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYP 232
+ ++ L++ NV ED G+Y C+ I +G Y V + ++ + G+ P I P
Sbjct: 159 YRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFS-LFPVIGAP 217
Query: 233 KNHSI-EVQLGTTLIVDCNVTDTKDNTNLRC--WRVNNTLVDDYYDESKRIREGVETHVS 289
+ I EV++G + C+ K L W++N T + D+ + + EG S
Sbjct: 218 AQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFS 277
Query: 290 FREHNLYTVNITFLEVKMEDYGLPFMCHA----GVS--TAYIILQLPAPDFRAYLIGGLI 343
L V + +VK ED L + C A G+ T + + P Y I +
Sbjct: 278 NGLACLDMV-LRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIAVC 336
Query: 344 ALVAVAVSV-VYIYNIFKIDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQRHA-- 400
++ + ++V V I +F I+ L +R +T DGKLYDAYV+YP+ +K S A
Sbjct: 337 SVFLMLINVLVIILKMFWIEATLLWRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDGASR 396
Query: 401 VDALVLNILPEVLERQCGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESLGFG 460
V+ V ILP+VLE +CGY L I+GRD PG+ V ++ N++ RR I I+ P+
Sbjct: 397 VEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTPQ----- 451
Query: 461 LLKNLS---EEQIAVYSALIQDGMKVILIELEKIEDYTV-----MPESIQYIKQKHGAIR 512
+ N E+++A++ ALIQ+ KVILIE+E + + + + +S+Q++ + G I+
Sbjct: 452 ITHNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTIK 511
Query: 513 WHGDFTEQSQCMKTKFWKTVRYHMP-----PRRCRPFPPV 547
W D + + +KFWK VRY MP PR+ P+
Sbjct: 512 WREDHIANKRSLNSKFWKHVRYQMPVPSKIPRKASSLTPL 551
>gi|11225607 interleukin 1 receptor accessory protein-like 2 [Homo
sapiens]
Length = 686
Score = 166 bits (421), Expect = 4e-41
Identities = 151/567 (26%), Positives = 257/567 (45%), Gaps = 57/567 (10%)
Query: 18 TADGCKD--IFMKNEILSASQPFAFNCT---------FPPITSGEVSVTWYKNSSKIPVS 66
+ DGC D + +K + A +P C + S + + WYKN +
Sbjct: 27 SVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSTAQSTGLRLMWYKNKGDLEEP 86
Query: 67 KIIQS-RIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGL 125
I R+ ++E I F E DSG Y CV++ C ++ ++LTV E G
Sbjct: 87 IIFSEVRMSKEEDSIWFHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENE-----SGLC 141
Query: 126 PNLSDEYKQILHLGKDDSLTCHL--HFPKSCVLGPIKWYKDCNEIKGERFTVLE--TRLL 181
N Y + + K ++C F KS + WYK+C K R +++ LL
Sbjct: 142 YNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKP-KMWRSIIIQKGNALL 200
Query: 182 VSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHS---IE 238
+ V ED GNY C+ L + GK L T + A PK ++P + I+
Sbjct: 201 IQEVQEEDGGNYTCE--LKYEGK----LVRRTTELKVTALLTDKPPKPLFPMENQPSVID 254
Query: 239 VQLGTTLIVDCNVTD--TKDNTNLRCWRVNNTLVDDYYDESKRIREG----VETHVSFRE 292
VQLG L + C + ++ + W +++ + IREG ++ H+ +E
Sbjct: 255 VQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEEL---AGHIREGEIRLLKEHLGEKE 311
Query: 293 HNLYTVNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFRAYLIGGLIALVAVAVSV 352
L + + +E + +Y G A ++L+ ++ L GGL A+ + V +
Sbjct: 312 VELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLVLL 371
Query: 353 VYIYNIFKIDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKES---QRHAVDALVLNIL 409
V IY + I+++L+YR F + ET D K YDAY+ Y K +++ + L +L
Sbjct: 372 VVIYKCYNIELMLFYRQHFGADETNDDNKEYDAYLSYTKVDQDTLDCDNPEEEQFALEVL 431
Query: 410 PEVLERQCGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESL---GFGLLKNLS 466
P+VLE+ GYKLFI RD P + V+ RRLI+++ P+ + G+ +
Sbjct: 432 PDVLEKHYGYKLFIPERDLIPSGTYMEDLTRYVEQSRRLIIVLTPDYILRRGWSIF---- 487
Query: 467 EEQIAVYSALIQDGMKVILIELEKIEDYTVMPESIQYIKQK---HGAIRWHGDFTEQSQC 523
E + +++ L+ +KVILIE +++ V + ++ +K+ I+W G +S
Sbjct: 488 ELESRLHNMLVSGEIKVILIECTELKG-KVNCQEVESLKRSIKLLSLIKWKG---SKSSK 543
Query: 524 MKTKFWKTVRYHMPPRRCRPFPPVQLL 550
+ +KFWK + Y MP ++ P +L
Sbjct: 544 LNSKFWKHLVYEMPIKKKEMLPRCHVL 570
>gi|7657232 interleukin 1 receptor accessory protein-like 1
precursor [Homo sapiens]
Length = 696
Score = 165 bits (417), Expect = 1e-40
Identities = 160/569 (28%), Positives = 261/569 (45%), Gaps = 58/569 (10%)
Query: 18 TADGCKD--IFMKNEILSASQPFAFNCT---------FPPITSGEVSVTWYKNSSKIPVS 66
+ADGC D I +K + +P C + S +S+ WYK+S
Sbjct: 27 SADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFE 86
Query: 67 KIIQ---SRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIG 123
+ I SR+ ++E I F P DSG+Y CVI+ C ++ ++LTV E DT +
Sbjct: 87 EPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGEN---DTGL- 142
Query: 124 GLPNLSDEYKQILHLGKDDSLTCH--LHFPKSCVLGPIKWYKDCNEIKGERFTVLETR-- 179
N +Y + L K ++C F I WYK+C K R +++ R
Sbjct: 143 -CYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRT-KTWRPSIVFKRDT 200
Query: 180 LLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSI-- 237
LL+ V +D GNY C+ L + G + T +T A PK++YP +
Sbjct: 201 LLIREVREDDIGNYTCE--LKYGG----FVVRRTTELTVTAPLTDKPPKLLYPMESKLTI 254
Query: 238 -EVQLGTTLIVDCNVTD--TKDNTNLRCWRVNNTLVDDYYDESKRIREG----VETHVSF 290
E QLG + + C + D + L W ++D + R+ E ++ H+
Sbjct: 255 QETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDL--DENRVWESDIRILKEHLGE 312
Query: 291 REHNLYTVNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFRAYLIGGLIALVAVAV 350
+E ++ + + E + +Y G A ++L + L GGL A++ + V
Sbjct: 313 QEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVELAGGLGAILLLLV 372
Query: 351 SVVYIYNIFKIDIVLWYRSAFHSTETIVDGKLYDAYVLYPK--PHKESQRHA-VDALVLN 407
+V IY +KI+I+L+YR+ F + E D K YDAY+ Y K P + +Q + L
Sbjct: 373 CLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWNQETGEEERFALE 432
Query: 408 ILPEVLERQCGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESL---GFGLLKN 464
ILP++LE+ GYKLFI RD P + V +RLI+++ P + G+ +
Sbjct: 433 ILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPNYVVRRGWSIF-- 490
Query: 465 LSEEQIAVYSALIQDGMKVILI---ELEKIEDYTVMPESIQYIKQKHGAIRWHGDFTEQS 521
E + + + L+ +KVILI EL I +Y + E++++ + I+WHG +
Sbjct: 491 --ELETRLRNMLVTGEIKVILIECSELRGIMNYQEV-EALKHTIKLLTVIKWHG---PKC 544
Query: 522 QCMKTKFWKTVRYHMPPRRCRPFPPVQLL 550
+ +KFWK ++Y MP +R P Q L
Sbjct: 545 NKLNSKFWKRLQYEMPFKRIEPITHEQAL 573
>gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens]
Length = 541
Score = 164 bits (416), Expect = 2e-40
Identities = 140/505 (27%), Positives = 236/505 (46%), Gaps = 48/505 (9%)
Query: 55 TWYKNSSK---IPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLT 111
+WYK+S + ++ SRI + + F P+E D+G Y +K + + +N+
Sbjct: 55 SWYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMK--NYTQKWKLNVI 112
Query: 112 VFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGE 171
KH C T +I+ + K +TC + ++ V YK+C ++ E
Sbjct: 113 RRNKHSCFTE-------RQVTSKIVEVKKFFQITCENSYYQTLV-NSTSLYKNCKKLLLE 164
Query: 172 RFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIY 231
+ + N ED+G Y+C L H+GK + + ++I E VP ++
Sbjct: 165 NN---KNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRS--NIVPVLLG 219
Query: 232 PKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIR----EGVETH 287
PK + + V+LG + ++C+ +++ + N D E K +R EG + H
Sbjct: 220 PKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGS-DPNIHEEKEMRIMTPEG-KWH 277
Query: 288 VS--FREHNLYTVNITFLEVKMEDYGLPFMCHAGVSTAYIIL-------QLPAPDFRAYL 338
S R N+ N+ L Y G T IL +P F +
Sbjct: 278 ASKVLRIENIGESNLNVL------YNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGM 331
Query: 339 IGGLIALVAVAVSVVYIYNIFKIDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQR 398
I ++ LVAV V +V + I+++D+VL+YR ET+ DGK YDA+V Y K +
Sbjct: 332 IIAVLILVAV-VCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENG 390
Query: 399 HAVDALVLNILPEVLERQCGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIVVPESLG 458
+ ILP VLE+ GYKL IF RD PG AV + I ++ RRLI+++ S
Sbjct: 391 EE-HTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVL---SKS 446
Query: 459 FGLLKNLSEEQIAVYSALIQDGMKVILIELEKIEDYTVMPESIQYIKQKHGAIRWHGDFT 518
+ + E + ++ AL++ +K+ILIE + D+T +P+S++ +K H ++W D
Sbjct: 447 YMSNEVRYELESGLHEALVERKIKIILIEFTPVTDFTFLPQSLKLLK-SHRVLKWKAD-- 503
Query: 519 EQSQCMKTKFWKTVRYHMPPRRCRP 543
+S ++FWK + Y MP + +P
Sbjct: 504 -KSLSYNSRFWKNLLYLMPAKTVKP 527
>gi|4504661 interleukin 1 receptor accessory protein isoform 1 [Homo
sapiens]
Length = 570
Score = 156 bits (395), Expect = 4e-38
Identities = 136/513 (26%), Positives = 246/513 (47%), Gaps = 46/513 (8%)
Query: 49 SGEVSVTWY----KNSSKIPVS-KIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSC 103
S +++ WY + P++ ++ ++RI +++ + F P D+G Y C+++ C
Sbjct: 63 SAGLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTTYC 122
Query: 104 HRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHL---HFPKSCVLGPIK 160
++ L V +K C S LP +K + G +TC +FP S V I
Sbjct: 123 SKVAFPLEVVQKDSCFNSPMKLP----VHKLYIEYGIQ-RITCPNVDGYFPSS-VKPTIT 176
Query: 161 WYKDCNEIKGERFTVLE---TRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSIT 217
WY C +I+ + E L++ +S + GNY C +G+ + + +TV +
Sbjct: 177 WYMGCYKIQNFNNVIPEGMNLSFLIALIS--NNGNYTCVVTYPENGRTFHLTRTLTVKVV 234
Query: 218 ERAGYGGSVPKIIY-PKNHSI-EVQLGTTLIVDCNV--TDTKDNTNLRCWRVNNTLVDDY 273
+VP +I+ P +H + E + G L++ C V + D+ N W ++ DD
Sbjct: 235 --GSPKNAVPPVIHSPNDHVVYEKEPGEELLIPCTVYFSFLMDSRNEVWWTIDGKKPDDI 292
Query: 274 YDESKRIREGVETHVSFREHNLYTVNITFLEVKMEDYGLPFMCHAG------VSTAYIIL 327
+ I E + S E T ++ +V ED ++CHA A +
Sbjct: 293 TIDVT-INESISH--SRTEDETRTQILSIKKVTSEDLKRSYVCHARSAKGEVAKAAKVKQ 349
Query: 328 QLPAPDFRAYLIGGLIALVAVAVSVVYIYNIFKIDIVLWYRSAFHSTETIVDGKLYDAYV 387
++PAP + L G A V + V ++ +Y+++ +++VL+YR+ F + ETI+DGK YD YV
Sbjct: 350 KVPAPRYTVELACGFGATVLLVVILIVVYHVYWLEMVLFYRAHFGTDETILDGKEYDIYV 409
Query: 388 LYPKPHKESQRHAVDALVLNILPEVLERQCGYKLFIFGRDEFPGQAVANVIDENVKLCRR 447
Y + +E + VL L VLE + GYKL IF RD PG V + ++ RR
Sbjct: 410 SYARNAEEEE------FVLLTLRGVLENEFGYKLCIFDRDSLPGGIVTDETLSFIQKSRR 463
Query: 448 LIVIVVPESLGFGLLKNLSEEQIAVYSALIQDGMKVILIELEKIEDYTVMPESIQYIKQK 507
L+V++ P + G + L E + + + + + VIL++ + +++ V + ++ K
Sbjct: 464 LLVVLSPNYVLQG-TQALLELKAGLENMASRGNINVILVQYKAVKETKV--KELKRAKTV 520
Query: 508 HGAIRWHGDFTEQSQCMKTKFWKTVRYHMPPRR 540
I+W G E+S+ + +FWK ++ MP ++
Sbjct: 521 LTVIKWKG---EKSKYPQGRFWKQLQVAMPVKK 550
>gi|4504657 interleukin 18 receptor accessory protein precursor
[Homo sapiens]
Length = 599
Score = 119 bits (298), Expect = 8e-27
Identities = 141/525 (26%), Positives = 228/525 (43%), Gaps = 44/525 (8%)
Query: 45 PPITSGEVS-VTWYKNSSK-IPVSKIIQSRIH--QDETWILFLPMEWGDSGVYQCVIKGR 100
P + S ++S V WY+ S P+ I +S H QD+ + FL +SG Y C K
Sbjct: 72 PFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMI 131
Query: 101 DSCHRIH--VNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGP 158
S + + V + + K + S S +KQ L LG S++C +S P
Sbjct: 132 KSPYDVACCVKMILEVKPQTNASC----EYSASHKQDLLLGSTGSISCPSLSCQSDAQSP 187
Query: 159 -IKWYKDCNEIKGERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSIT 217
+ WYK+ + ER R++V V +G Y C + + + V V +
Sbjct: 188 AVTWYKNGKLLSVER----SNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVR--AVVQVR 241
Query: 218 ERAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDES 277
G P I+ P ++EV+LG L + C + RV N ++ Y +S
Sbjct: 242 TIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFE-------RVFNPVIKWYIKDS 294
Query: 278 KRIRE----GVETHVSFREHNLYTVNITFLEVKMEDYGLPFMCHA----GVSTAYIILQL 329
E ++ S + + NI +V D F+C G +T + L+
Sbjct: 295 DLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKE 354
Query: 330 PAPDFRAYLIGGLIA-LVAVAVSVVYIYNIFKIDIVLWYRSAFHSTETIVDGKLYDAYVL 388
Y++ G I LVAV + +Y + I+IVL YR+ +T+ D K +DA+V
Sbjct: 355 KRGVVLLYILLGTIGTLVAVLAASALLYRHW-IEIVLLYRTYQSKDQTLGDKKDFDAFVS 413
Query: 389 YPK----PHKESQRHAVDALVLNILPEVLERQCGYKLFIFGRDEFPGQAVANVIDENVKL 444
Y K P + + + + L L++ P+VLE + GY L + RD PG A I +K
Sbjct: 414 YAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKR 473
Query: 445 CRRLIVIVVPESLGFGLLKNLSEEQIAVYSALIQDGMKVILIELEKIEDYTVMPESIQYI 504
RR I I+ P + ++ E Q AV AL +K+ILI+ ++ +P ++
Sbjct: 474 SRRGIFILSPNYVNG---PSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKA 530
Query: 505 KQKHGAIRWHGDFTEQSQCMKTKFWKTVRYHMPPRRCRPFPPVQL 549
+ + W G +S ++FW +RYHMP + + F QL
Sbjct: 531 LRVLPTVTWRG---LKSVPPNSRFWAKMRYHMPVKNSQGFTWNQL 572
>gi|27894334 interleukin 1 receptor, type II precursor [Homo
sapiens]
Length = 398
Score = 103 bits (258), Expect = 3e-22
Identities = 90/303 (29%), Positives = 129/303 (42%), Gaps = 26/303 (8%)
Query: 28 KNEILSASQPFAFNCTFPPI-----TSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILF 82
K E +P A C P S +++TW+KN S V ++R+ + +
Sbjct: 36 KREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWL 95
Query: 83 LPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDD 142
LP DSG Y C + C ++ + L VFE + LP +S Y QIL L
Sbjct: 96 LPALQEDSGTYVCTTRNASYCDKMSIELRVFEN-----TDAFLPFIS--YPQILTLSTSG 148
Query: 143 SLTCH--LHFPKSCVLGPIKWYKDCNEIK--GERFTVLE--TRLLVSNVSAEDRGNYACQ 196
L C F + I+WYKD + E+F + T LLV +V+ ED G Y C
Sbjct: 149 VLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCV 208
Query: 197 AILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNV---TD 253
H G+QY + I + I ++ ++P II P +I LG+ L + C V T
Sbjct: 209 LTFAHEGQQYNITRSIELRIKKKKEE--TIPVIISPLK-TISASLGSRLTIPCKVFLGTG 265
Query: 254 TKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYTVNITFLEVKMEDYGLP 313
T T L W N+T ++ Y R+ EG S N V + F V ED +
Sbjct: 266 TPLTTML-WWTANDTHIESAYPGG-RVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMD 323
Query: 314 FMC 316
F C
Sbjct: 324 FKC 326
>gi|4758598 interleukin 1 receptor, type II precursor [Homo sapiens]
Length = 398
Score = 103 bits (258), Expect = 3e-22
Identities = 90/303 (29%), Positives = 129/303 (42%), Gaps = 26/303 (8%)
Query: 28 KNEILSASQPFAFNCTFPPI-----TSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILF 82
K E +P A C P S +++TW+KN S V ++R+ + +
Sbjct: 36 KREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWL 95
Query: 83 LPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDD 142
LP DSG Y C + C ++ + L VFE + LP +S Y QIL L
Sbjct: 96 LPALQEDSGTYVCTTRNASYCDKMSIELRVFEN-----TDAFLPFIS--YPQILTLSTSG 148
Query: 143 SLTCH--LHFPKSCVLGPIKWYKDCNEIK--GERFTVLE--TRLLVSNVSAEDRGNYACQ 196
L C F + I+WYKD + E+F + T LLV +V+ ED G Y C
Sbjct: 149 VLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCV 208
Query: 197 AILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNV---TD 253
H G+QY + I + I ++ ++P II P +I LG+ L + C V T
Sbjct: 209 LTFAHEGQQYNITRSIELRIKKKKEE--TIPVIISPLK-TISASLGSRLTIPCKVFLGTG 265
Query: 254 TKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYTVNITFLEVKMEDYGLP 313
T T L W N+T ++ Y R+ EG S N V + F V ED +
Sbjct: 266 TPLTTML-WWTANDTHIESAYPGG-RVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMD 323
Query: 314 FMC 316
F C
Sbjct: 324 FKC 326
>gi|27894328 interleukin 1 receptor-like 1 isoform 2 precursor [Homo
sapiens]
Length = 328
Score = 84.0 bits (206), Expect = 4e-16
Identities = 65/269 (24%), Positives = 121/269 (44%), Gaps = 11/269 (4%)
Query: 53 SVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTV 112
+V WY + + + ++R+ + FLP DSG+Y C+++ + N+T+
Sbjct: 45 TVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTI 104
Query: 113 FEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGER 172
++K S +P+ Y + K+ + C + P++W+K+C ++G R
Sbjct: 105 YKKQ----SDCNVPDYL-MYSTVSGSEKNSKIYCPTIDLYNWT-APLEWFKNCQALQGSR 158
Query: 173 FTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYP 232
+ ++ L++ NV ED G+Y C+ I +G Y V + ++ + G+ P I P
Sbjct: 159 YRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGF-SLFPVIGAP 217
Query: 233 KNHSI-EVQLGTTLIVDCNVTDTKDNTNLRC--WRVNNTLVDDYYDESKRIREGVETHVS 289
+ I EV++G + C+ K L W++N T + D+ + + EG S
Sbjct: 218 AQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFS 277
Query: 290 FREHNLYTVNITFLEVKMEDYGLPFMCHA 318
L V + +VK ED L + C A
Sbjct: 278 NGLACLDMV-LRIADVKEEDLLLQYDCLA 305
>gi|205277451 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 68.9 bits (167), Expect = 1e-11
Identities = 53/156 (33%), Positives = 82/156 (52%), Gaps = 13/156 (8%)
Query: 298 VNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFR-AYLIGGLIALVAVAVSVVYIY 356
VN+T EV YG +S + LQ P A ++ L+ L+A+ ++ + +Y
Sbjct: 85 VNVTSTEV----YGAFTCSIQNISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAAL-LY 139
Query: 357 NIFKIDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQRHAVDALVLNILPEVLERQ 416
+++++LWY+ A+ E I DGKLYDAYV Y ++ + V IL LER+
Sbjct: 140 VKCRLNVLLWYQDAYGEVE-INDGKLYDAYVSYSDCPEDRK------FVNFILKPQLERR 192
Query: 417 CGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIV 452
GYKLF+ RD P + + N+ CRRLIV++
Sbjct: 193 RGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVL 228
>gi|205277449 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 68.9 bits (167), Expect = 1e-11
Identities = 53/156 (33%), Positives = 82/156 (52%), Gaps = 13/156 (8%)
Query: 298 VNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFR-AYLIGGLIALVAVAVSVVYIY 356
VN+T EV YG +S + LQ P A ++ L+ L+A+ ++ + +Y
Sbjct: 85 VNVTSTEV----YGAFTCSIQNISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAAL-LY 139
Query: 357 NIFKIDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQRHAVDALVLNILPEVLERQ 416
+++++LWY+ A+ E I DGKLYDAYV Y ++ + V IL LER+
Sbjct: 140 VKCRLNVLLWYQDAYGEVE-INDGKLYDAYVSYSDCPEDRK------FVNFILKPQLERR 192
Query: 417 CGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIV 452
GYKLF+ RD P + + N+ CRRLIV++
Sbjct: 193 RGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVL 228
>gi|205277445 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 68.9 bits (167), Expect = 1e-11
Identities = 53/156 (33%), Positives = 82/156 (52%), Gaps = 13/156 (8%)
Query: 298 VNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFR-AYLIGGLIALVAVAVSVVYIY 356
VN+T EV YG +S + LQ P A ++ L+ L+A+ ++ + +Y
Sbjct: 85 VNVTSTEV----YGAFTCSIQNISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAAL-LY 139
Query: 357 NIFKIDIVLWYRSAFHSTETIVDGKLYDAYVLYPKPHKESQRHAVDALVLNILPEVLERQ 416
+++++LWY+ A+ E I DGKLYDAYV Y ++ + V IL LER+
Sbjct: 140 VKCRLNVLLWYQDAYGEVE-INDGKLYDAYVSYSDCPEDRK------FVNFILKPQLERR 192
Query: 417 CGYKLFIFGRDEFPGQAVANVIDENVKLCRRLIVIV 452
GYKLF+ RD P + + N+ CRRLIV++
Sbjct: 193 RGYKLFLDDRDLLPRAEPSADLLVNLSRCRRLIVVL 228
>gi|19882209 interleukin 1 receptor accessory protein isoform 2
[Homo sapiens]
Length = 356
Score = 65.9 bits (159), Expect = 1e-10
Identities = 68/285 (23%), Positives = 126/285 (44%), Gaps = 28/285 (9%)
Query: 49 SGEVSVTWY----KNSSKIPVS-KIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSC 103
S +++ WY + P++ ++ ++RI +++ + F P D+G Y C+++ C
Sbjct: 63 SAGLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTTYC 122
Query: 104 HRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTC---HLHFPKSCVLGPIK 160
++ L V +K C S LP +K + G +TC +FP S V I
Sbjct: 123 SKVAFPLEVVQKDSCFNSPMKLP----VHKLYIEYG-IQRITCPNVDGYFPSS-VKPTIT 176
Query: 161 WYKDCNEIKGERFTV---LETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSIT 217
WY C +I+ + + L++ +S + GNY C +G+ + + +TV +
Sbjct: 177 WYMGCYKIQNFNNVIPEGMNLSFLIALIS--NNGNYTCVVTYPENGRTFHLTRTLTVKVV 234
Query: 218 ERAGYGGSVPKIIY-PKNHSI-EVQLGTTLIVDCNV--TDTKDNTNLRCWRVNNTLVDDY 273
+VP +I+ P +H + E + G L++ C V + D+ N W ++ DD
Sbjct: 235 --GSPKNAVPPVIHSPNDHVVYEKEPGEELLIPCTVYFSFLMDSRNEVWWTIDGKKPDDI 292
Query: 274 YDESKRIREGVETHVSFREHNLYTVNITFLEVKMEDYGLPFMCHA 318
+ I E + S E T ++ +V ED ++CHA
Sbjct: 293 TID-VTINESISH--SRTEDETRTQILSIKKVTSEDLKRSYVCHA 334
>gi|81158226 neuronal cell adhesion molecule isoform A precursor
[Homo sapiens]
Length = 1304
Score = 48.9 bits (115), Expect = 1e-05
Identities = 47/174 (27%), Positives = 75/174 (43%), Gaps = 27/174 (15%)
Query: 34 ASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQD-----ETWILFLPMEWG 88
A++P +C F S ++ W+K + S +H+D E L +P+
Sbjct: 468 ANRPALLDCAF--FGSPLPTIEWFKGAKG--------SALHEDIYVLHENGTLEIPVAQK 517
Query: 89 DS-GVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCH 147
DS G Y CV + + + V+L + + W EY ++ G S C
Sbjct: 518 DSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQ--------PEYA-VVQRGSMVSFECK 568
Query: 148 LHFPKSCVLGPIKWYKDCNEIKG-ERFTVLETRLLVSNVSAEDRGNYACQAILT 200
+ + L + W KD E+ ERFTV + L+V++VS +D G Y C A T
Sbjct: 569 VKHDHTLSL-TVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTT 621
Score = 30.0 bits (66), Expect = 6.0
Identities = 44/205 (21%), Positives = 77/205 (37%), Gaps = 39/205 (19%)
Query: 54 VTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVF 113
+ W K +P ++ + E + + + DSG YQC+ K ++ IH ++V
Sbjct: 302 IYWAKEDGMLPKNRTVYKNF---EKTLQIIHVSEADSGNYQCIAK--NALGAIHHTISVR 356
Query: 114 EK---HWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLH-FPKSCVLG-----PIKWYKD 164
K +W ++ +L G+D +L C + PK + PI+ D
Sbjct: 357 VKAAPYW----------ITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPD 406
Query: 165 CNEIKGERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGG 224
K + T+ + SNV Y C A + Y + N + E
Sbjct: 407 DPSRKIDGDTI-----IFSNVQERSSAVYQCNASNEYG---YLLANAFVNVLAE------ 452
Query: 225 SVPKIIYPKNHSIEVQLGTTLIVDC 249
P+I+ P N +V ++DC
Sbjct: 453 -PPRILTPANTLYQVIANRPALLDC 476
>gi|81158224 neuronal cell adhesion molecule isoform B precursor
[Homo sapiens]
Length = 1183
Score = 48.9 bits (115), Expect = 1e-05
Identities = 47/174 (27%), Positives = 75/174 (43%), Gaps = 27/174 (15%)
Query: 34 ASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQD-----ETWILFLPMEWG 88
A++P +C F S ++ W+K + S +H+D E L +P+
Sbjct: 462 ANRPALLDCAF--FGSPLPTIEWFKGAKG--------SALHEDIYVLHENGTLEIPVAQK 511
Query: 89 DS-GVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCH 147
DS G Y CV + + + V+L + + W EY ++ G S C
Sbjct: 512 DSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQ--------PEYA-VVQRGSMVSFECK 562
Query: 148 LHFPKSCVLGPIKWYKDCNEIKG-ERFTVLETRLLVSNVSAEDRGNYACQAILT 200
+ + L + W KD E+ ERFTV + L+V++VS +D G Y C A T
Sbjct: 563 VKHDHTLSL-TVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTT 615
Score = 30.0 bits (66), Expect = 6.0
Identities = 44/205 (21%), Positives = 77/205 (37%), Gaps = 39/205 (19%)
Query: 54 VTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVF 113
+ W K +P ++ + E + + + DSG YQC+ K ++ IH ++V
Sbjct: 296 IYWAKEDGMLPKNRTVYKNF---EKTLQIIHVSEADSGNYQCIAK--NALGAIHHTISVR 350
Query: 114 EK---HWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLH-FPKSCVLG-----PIKWYKD 164
K +W ++ +L G+D +L C + PK + PI+ D
Sbjct: 351 VKAAPYW----------ITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPD 400
Query: 165 CNEIKGERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGG 224
K + T+ + SNV Y C A + Y + N + E
Sbjct: 401 DPSRKIDGDTI-----IFSNVQERSSAVYQCNASNEYG---YLLANAFVNVLAE------ 446
Query: 225 SVPKIIYPKNHSIEVQLGTTLIVDC 249
P+I+ P N +V ++DC
Sbjct: 447 -PPRILTPANTLYQVIANRPALLDC 470
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 44.7 bits (104), Expect = 2e-04
Identities = 45/220 (20%), Positives = 84/220 (38%), Gaps = 42/220 (19%)
Query: 47 ITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRI 106
+ + VTWYK+ K+ S + + ++ D+G Y C G+ +
Sbjct: 1098 VAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHL 1157
Query: 107 HVNLT--VFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKD 164
H+ VF K ++ +E + G L+C + P++ + WYKD
Sbjct: 1158 HITEPKGVFAKE---------QSVHNEVQA--EAGTTAMLSCEVAQPQT----EVTWYKD 1202
Query: 165 CNEIKGERFTVLET-----RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITER 219
++ +E RL+V V D G Y+C+A G++ + ITE
Sbjct: 1203 GKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRV----SFQLHITE- 1253
Query: 220 AGYGGSVPKIIYPK----NHSIEVQLGTTLIVDCNVTDTK 255
PK ++ K ++ + + G + + C V +
Sbjct: 1254 -------PKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQ 1286
Score = 41.2 bits (95), Expect = 0.003
Identities = 54/263 (20%), Positives = 100/263 (38%), Gaps = 57/263 (21%)
Query: 9 LSIALPLSVTADGCKDIFMKNEILS-ASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSK 67
L I P +V A K+ + NE+ + A +C + + VTWYK+ K+ S
Sbjct: 1249 LHITEPKAVFA---KEQLVHNEVRTEAGASATLSCE---VAQAQTEVTWYKDGKKLSSSS 1302
Query: 68 IIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPN 127
++ ++ D+G Y C G+ R+ +L V E P
Sbjct: 1303 KVRIEAAGCMRQLVVQQAGQADAGEYTCEAGGQ----RLSFHLDVSE-----------PK 1347
Query: 128 LSDEYKQILH------LGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLET--- 178
+Q+ H G +L+C + ++ + WYKD ++ +E
Sbjct: 1348 AVFAKEQLAHRKVQAEAGAIATLSCEVAQAQT----EVTWYKDGKKLSSSSKVRMEAVGC 1403
Query: 179 --RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIY----P 232
RL+V D G Y+C+A G++ ++ + E PK+++ P
Sbjct: 1404 TRRLVVQQACQADTGEYSCEA----GGQRL----SFSLDVAE--------PKVVFAKEQP 1447
Query: 233 KNHSIEVQLGTTLIVDCNVTDTK 255
+ ++ Q G + + C V +
Sbjct: 1448 VHREVQAQAGASTTLSCEVAQAQ 1470
Score = 40.8 bits (94), Expect = 0.003
Identities = 47/224 (20%), Positives = 86/224 (38%), Gaps = 50/224 (22%)
Query: 47 ITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRI 106
+ + VTWYK+ K+ S + ++ D+G Y C G+ R+
Sbjct: 914 VAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQ----RL 969
Query: 107 HVNLTVFEKHWCDTSIGGLPNLSDEYKQILH------LGKDDSLTCHLHFPKSCVLGPIK 160
+L V E P + Q+ H G +L+C + ++ V+
Sbjct: 970 SFHLDVKE-----------PKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVM---- 1014
Query: 161 WYKDCNEIKGERFTVLET-----RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVS 215
WYKD ++ +E RL+V D G+Y+C+A G++ +
Sbjct: 1015 WYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA----RGQRV----SFRLH 1066
Query: 216 ITERAGYGGSVPKIIYPKNHS----IEVQLGTTLIVDCNVTDTK 255
ITE PK+++ K S ++ + G + ++ C V +
Sbjct: 1067 ITE--------PKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQ 1102
Score = 38.1 bits (87), Expect = 0.022
Identities = 43/218 (19%), Positives = 83/218 (38%), Gaps = 50/218 (22%)
Query: 53 SVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTV 112
+VTW K+ + + + +L + D+G+Y+CV +G +++ V
Sbjct: 736 AVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLA 795
Query: 113 FEKHW-----CDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNE 167
H C ++ G P + ++ H+H + WYKD E
Sbjct: 796 RFLHKDMAGSCVDAVAGGPAQFE----------CETSEAHVH---------VHWYKDGME 836
Query: 168 I--KGERFTVLET----RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAG 221
+ GERF + RL+ + V+ +D G Y+C+ + +V R
Sbjct: 837 LGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCR------------VGEDSVDFRLRV- 883
Query: 222 YGGSVPKIIYPK----NHSIEVQLGTTLIVDCNVTDTK 255
S PK+++ K ++ + G + + C V +
Sbjct: 884 ---SEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQ 918
Score = 36.2 bits (82), Expect = 0.084
Identities = 32/159 (20%), Positives = 59/159 (37%), Gaps = 24/159 (15%)
Query: 47 ITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRI 106
+ + VTWYK+ K+ S ++ ++ D+G Y C + +
Sbjct: 1558 VAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHL 1617
Query: 107 HV--NLTVFEKHWCDTSIGGLPNLSDEYKQI-LHLGKDDSLTCHLHFPKSCVLGPIKWYK 163
HV VF K ++++ G +L+C + ++ + WYK
Sbjct: 1618 HVAEPKVVFAKE------------QPAHREVQAEAGASATLSCEVAQAQT----EVTWYK 1661
Query: 164 DCNEIKGERFTVLET-----RLLVSNVSAEDRGNYACQA 197
D ++ +E RL+V D G Y+C+A
Sbjct: 1662 DGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEA 1700
Score = 34.3 bits (77), Expect = 0.32
Identities = 40/193 (20%), Positives = 73/193 (37%), Gaps = 41/193 (21%)
Query: 36 QPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQC 95
Q +C F P +V WYK+ + + S+ + + + L + D+GVY+C
Sbjct: 2484 QSVVLSCDFRPAPK---AVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRC 2540
Query: 96 VIKGRDSCHRIHV------------NLTVFEKHWC-------------DTSIGGLPNLSD 130
S + V + E+ W + S+ G+P +D
Sbjct: 2541 QAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLYND 2600
Query: 131 EYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETRL-------LVS 183
+ +I H G+ +L L + G ++ + +K LE R+ +
Sbjct: 2601 SFHEISHKGRRHTLV--LKSIQRADAGIVR----ASSLKVSTSARLEVRVKPVVFLKALD 2654
Query: 184 NVSAEDRGNYACQ 196
++SAE+RG A Q
Sbjct: 2655 DLSAEERGTLALQ 2667
Score = 33.9 bits (76), Expect = 0.42
Identities = 36/154 (23%), Positives = 60/154 (38%), Gaps = 29/154 (18%)
Query: 51 EVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGR--DSCHRIHV 108
++ V W K+ + S Q +L DSG Y+C G S R+H
Sbjct: 3123 DIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHA 3182
Query: 109 NLTVFEKHWCDTSI--GGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCN 166
F++ D + GG +L C L S V P+KW N
Sbjct: 3183 RPVRFQEALKDLEVLEGGAA----------------TLRCVL----SSVAAPVKWCYGNN 3222
Query: 167 EIK-GERFTVLET----RLLVSNVSAEDRGNYAC 195
++ G+++++ + L+V N+ +D G Y+C
Sbjct: 3223 VLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC 3256
Score = 32.0 bits (71), Expect = 1.6
Identities = 28/123 (22%), Positives = 47/123 (38%), Gaps = 12/123 (9%)
Query: 47 ITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRI 106
+ + VTWYK+ K+ S ++ ++ D+G Y C G+ R+
Sbjct: 1650 VAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRL 1709
Query: 107 HVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCN 166
HV E + P + E++ I+ LT L P + + W KD
Sbjct: 1710 HV--AELEPQISERPCRREPLVVKEHEDII-------LTATLATPSAAT---VTWLKDGV 1757
Query: 167 EIK 169
EI+
Sbjct: 1758 EIR 1760
Score = 31.2 bits (69), Expect = 2.7
Identities = 41/220 (18%), Positives = 78/220 (35%), Gaps = 42/220 (19%)
Query: 47 ITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRI 106
+ + V WYK+ K+ S ++ ++ +G Y C + +
Sbjct: 1466 VAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHL 1525
Query: 107 HV--NLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKD 164
HV VF K S E + G +L+C + ++ + WYKD
Sbjct: 1526 HVAEPKAVFAKE---------QPASREVQ--AEAGTSATLSCEVAQAQT----EVTWYKD 1570
Query: 165 CNEIKGERFTVLET-----RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITER 219
++ +E RL+V D G Y+C+A G Q + + + E
Sbjct: 1571 GKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA-----GDQRLSFH---LHVAE- 1621
Query: 220 AGYGGSVPKIIY----PKNHSIEVQLGTTLIVDCNVTDTK 255
PK+++ P + ++ + G + + C V +
Sbjct: 1622 -------PKVVFAKEQPAHREVQAEAGASATLSCEVAQAQ 1654
Score = 31.2 bits (69), Expect = 2.7
Identities = 39/192 (20%), Positives = 72/192 (37%), Gaps = 39/192 (20%)
Query: 48 TSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIH 107
T +VTW K+ +I SK ++ D + + DS +Y C + +
Sbjct: 1744 TPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQ 1803
Query: 108 VNLTVFEKHWCDTSIGGLPNLSDEYKQILH-----LGKDDSLTCHLHFPKSCVLGPIKWY 162
V ++ ++ ++L LG +L C L S + W
Sbjct: 1804 VE-----------------EVAAKFCRLLEPVCGELGGTVTLACEL----SPACAEVVWR 1842
Query: 163 KDCNEIK-GERFTVLET----RLLVSNVSAEDRGNYACQAILTHSGKQYEV--------L 209
+++ G+RF ++ L V + AED G Y C++ H+ Q V +
Sbjct: 1843 CGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFM 1902
Query: 210 NGITVSITERAG 221
+G++ + E G
Sbjct: 1903 SGLSTVVAEEGG 1914
Score = 30.4 bits (67), Expect = 4.6
Identities = 14/44 (31%), Positives = 26/44 (59%), Gaps = 5/44 (11%)
Query: 159 IKWYKDCNEIK-GERFTV----LETRLLVSNVSAEDRGNYACQA 197
++W+K E++ G ++ + L +L++S+V AED Y C A
Sbjct: 2320 VRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363
Score = 30.0 bits (66), Expect = 6.0
Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 9/64 (14%)
Query: 139 GKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLE-----TRLLVSNVSAEDRGNY 193
G+D +L C +C + P+ W KD ++G L +LL++ + +D G Y
Sbjct: 3110 GEDLTLVCET---STCDI-PVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRY 3165
Query: 194 ACQA 197
C+A
Sbjct: 3166 KCEA 3169
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 44.7 bits (104), Expect = 2e-04
Identities = 45/220 (20%), Positives = 84/220 (38%), Gaps = 42/220 (19%)
Query: 47 ITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRI 106
+ + VTWYK+ K+ S + + ++ D+G Y C G+ +
Sbjct: 1098 VAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHL 1157
Query: 107 HVNLT--VFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKD 164
H+ VF K ++ +E + G L+C + P++ + WYKD
Sbjct: 1158 HITEPKGVFAKE---------QSVHNEVQA--EAGTTAMLSCEVAQPQT----EVTWYKD 1202
Query: 165 CNEIKGERFTVLET-----RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITER 219
++ +E RL+V V D G Y+C+A G++ + ITE
Sbjct: 1203 GKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA----GGQRV----SFQLHITE- 1253
Query: 220 AGYGGSVPKIIYPK----NHSIEVQLGTTLIVDCNVTDTK 255
PK ++ K ++ + + G + + C V +
Sbjct: 1254 -------PKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQ 1286
Score = 41.2 bits (95), Expect = 0.003
Identities = 54/263 (20%), Positives = 100/263 (38%), Gaps = 57/263 (21%)
Query: 9 LSIALPLSVTADGCKDIFMKNEILS-ASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSK 67
L I P +V A K+ + NE+ + A +C + + VTWYK+ K+ S
Sbjct: 1249 LHITEPKAVFA---KEQLVHNEVRTEAGASATLSCE---VAQAQTEVTWYKDGKKLSSSS 1302
Query: 68 IIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPN 127
++ ++ D+G Y C G+ R+ +L V E P
Sbjct: 1303 KVRIEAAGCMRQLVVQQAGQADAGEYTCEAGGQ----RLSFHLDVSE-----------PK 1347
Query: 128 LSDEYKQILH------LGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLET--- 178
+Q+ H G +L+C + ++ + WYKD ++ +E
Sbjct: 1348 AVFAKEQLAHRKVQAEAGAIATLSCEVAQAQT----EVTWYKDGKKLSSSSKVRMEAVGC 1403
Query: 179 --RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIY----P 232
RL+V D G Y+C+A G++ ++ + E PK+++ P
Sbjct: 1404 TRRLVVQQACQADTGEYSCEA----GGQRL----SFSLDVAE--------PKVVFAKEQP 1447
Query: 233 KNHSIEVQLGTTLIVDCNVTDTK 255
+ ++ Q G + + C V +
Sbjct: 1448 VHREVQAQAGASTTLSCEVAQAQ 1470
Score = 40.8 bits (94), Expect = 0.003
Identities = 47/224 (20%), Positives = 86/224 (38%), Gaps = 50/224 (22%)
Query: 47 ITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRI 106
+ + VTWYK+ K+ S + ++ D+G Y C G+ R+
Sbjct: 914 VAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQ----RL 969
Query: 107 HVNLTVFEKHWCDTSIGGLPNLSDEYKQILH------LGKDDSLTCHLHFPKSCVLGPIK 160
+L V E P + Q+ H G +L+C + ++ V+
Sbjct: 970 SFHLDVKE-----------PKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVM---- 1014
Query: 161 WYKDCNEIKGERFTVLET-----RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVS 215
WYKD ++ +E RL+V D G+Y+C+A G++ +
Sbjct: 1015 WYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA----RGQRV----SFRLH 1066
Query: 216 ITERAGYGGSVPKIIYPKNHS----IEVQLGTTLIVDCNVTDTK 255
ITE PK+++ K S ++ + G + ++ C V +
Sbjct: 1067 ITE--------PKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQ 1102
Score = 38.1 bits (87), Expect = 0.022
Identities = 43/218 (19%), Positives = 83/218 (38%), Gaps = 50/218 (22%)
Query: 53 SVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTV 112
+VTW K+ + + + +L + D+G+Y+CV +G +++ V
Sbjct: 736 AVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLA 795
Query: 113 FEKHW-----CDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNE 167
H C ++ G P + ++ H+H + WYKD E
Sbjct: 796 RFLHKDMAGSCVDAVAGGPAQFE----------CETSEAHVH---------VHWYKDGME 836
Query: 168 I--KGERFTVLET----RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAG 221
+ GERF + RL+ + V+ +D G Y+C+ + +V R
Sbjct: 837 LGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCR------------VGEDSVDFRLRV- 883
Query: 222 YGGSVPKIIYPK----NHSIEVQLGTTLIVDCNVTDTK 255
S PK+++ K ++ + G + + C V +
Sbjct: 884 ---SEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQ 918
Score = 36.2 bits (82), Expect = 0.084
Identities = 32/159 (20%), Positives = 59/159 (37%), Gaps = 24/159 (15%)
Query: 47 ITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRI 106
+ + VTWYK+ K+ S ++ ++ D+G Y C + +
Sbjct: 1558 VAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHL 1617
Query: 107 HV--NLTVFEKHWCDTSIGGLPNLSDEYKQI-LHLGKDDSLTCHLHFPKSCVLGPIKWYK 163
HV VF K ++++ G +L+C + ++ + WYK
Sbjct: 1618 HVAEPKVVFAKE------------QPAHREVQAEAGASATLSCEVAQAQT----EVTWYK 1661
Query: 164 DCNEIKGERFTVLET-----RLLVSNVSAEDRGNYACQA 197
D ++ +E RL+V D G Y+C+A
Sbjct: 1662 DGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEA 1700
Score = 34.3 bits (77), Expect = 0.32
Identities = 40/193 (20%), Positives = 73/193 (37%), Gaps = 41/193 (21%)
Query: 36 QPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQC 95
Q +C F P +V WYK+ + + S+ + + + L + D+GVY+C
Sbjct: 2484 QSVVLSCDFRPAPK---AVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRC 2540
Query: 96 VIKGRDSCHRIHV------------NLTVFEKHWC-------------DTSIGGLPNLSD 130
S + V + E+ W + S+ G+P +D
Sbjct: 2541 QAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLYND 2600
Query: 131 EYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETRL-------LVS 183
+ +I H G+ +L L + G ++ + +K LE R+ +
Sbjct: 2601 SFHEISHKGRRHTLV--LKSIQRADAGIVR----ASSLKVSTSARLEVRVKPVVFLKALD 2654
Query: 184 NVSAEDRGNYACQ 196
++SAE+RG A Q
Sbjct: 2655 DLSAEERGTLALQ 2667
Score = 33.9 bits (76), Expect = 0.42
Identities = 36/154 (23%), Positives = 60/154 (38%), Gaps = 29/154 (18%)
Query: 51 EVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGR--DSCHRIHV 108
++ V W K+ + S Q +L DSG Y+C G S R+H
Sbjct: 3123 DIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHA 3182
Query: 109 NLTVFEKHWCDTSI--GGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCN 166
F++ D + GG +L C L S V P+KW N
Sbjct: 3183 RPVRFQEALKDLEVLEGGAA----------------TLRCVL----SSVAAPVKWCYGNN 3222
Query: 167 EIK-GERFTVLET----RLLVSNVSAEDRGNYAC 195
++ G+++++ + L+V N+ +D G Y+C
Sbjct: 3223 VLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC 3256
Score = 32.0 bits (71), Expect = 1.6
Identities = 28/123 (22%), Positives = 47/123 (38%), Gaps = 12/123 (9%)
Query: 47 ITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRI 106
+ + VTWYK+ K+ S ++ ++ D+G Y C G+ R+
Sbjct: 1650 VAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRL 1709
Query: 107 HVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCN 166
HV E + P + E++ I+ LT L P + + W KD
Sbjct: 1710 HV--AELEPQISERPCRREPLVVKEHEDII-------LTATLATPSAAT---VTWLKDGV 1757
Query: 167 EIK 169
EI+
Sbjct: 1758 EIR 1760
Score = 31.2 bits (69), Expect = 2.7
Identities = 41/220 (18%), Positives = 78/220 (35%), Gaps = 42/220 (19%)
Query: 47 ITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRI 106
+ + V WYK+ K+ S ++ ++ +G Y C + +
Sbjct: 1466 VAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHL 1525
Query: 107 HV--NLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKD 164
HV VF K S E + G +L+C + ++ + WYKD
Sbjct: 1526 HVAEPKAVFAKE---------QPASREVQ--AEAGTSATLSCEVAQAQT----EVTWYKD 1570
Query: 165 CNEIKGERFTVLET-----RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITER 219
++ +E RL+V D G Y+C+A G Q + + + E
Sbjct: 1571 GKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA-----GDQRLSFH---LHVAE- 1621
Query: 220 AGYGGSVPKIIY----PKNHSIEVQLGTTLIVDCNVTDTK 255
PK+++ P + ++ + G + + C V +
Sbjct: 1622 -------PKVVFAKEQPAHREVQAEAGASATLSCEVAQAQ 1654
Score = 31.2 bits (69), Expect = 2.7
Identities = 39/192 (20%), Positives = 72/192 (37%), Gaps = 39/192 (20%)
Query: 48 TSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIH 107
T +VTW K+ +I SK ++ D + + DS +Y C + +
Sbjct: 1744 TPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQ 1803
Query: 108 VNLTVFEKHWCDTSIGGLPNLSDEYKQILH-----LGKDDSLTCHLHFPKSCVLGPIKWY 162
V ++ ++ ++L LG +L C L S + W
Sbjct: 1804 VE-----------------EVAAKFCRLLEPVCGELGGTVTLACEL----SPACAEVVWR 1842
Query: 163 KDCNEIK-GERFTVLET----RLLVSNVSAEDRGNYACQAILTHSGKQYEV--------L 209
+++ G+RF ++ L V + AED G Y C++ H+ Q V +
Sbjct: 1843 CGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFM 1902
Query: 210 NGITVSITERAG 221
+G++ + E G
Sbjct: 1903 SGLSTVVAEEGG 1914
Score = 30.4 bits (67), Expect = 4.6
Identities = 14/44 (31%), Positives = 26/44 (59%), Gaps = 5/44 (11%)
Query: 159 IKWYKDCNEIK-GERFTV----LETRLLVSNVSAEDRGNYACQA 197
++W+K E++ G ++ + L +L++S+V AED Y C A
Sbjct: 2320 VRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363
Score = 30.0 bits (66), Expect = 6.0
Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 9/64 (14%)
Query: 139 GKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLE-----TRLLVSNVSAEDRGNY 193
G+D +L C +C + P+ W KD ++G L +LL++ + +D G Y
Sbjct: 3110 GEDLTLVCET---STCDI-PVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRY 3165
Query: 194 ACQA 197
C+A
Sbjct: 3166 KCEA 3169
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 43.9 bits (102), Expect = 4e-04
Identities = 75/352 (21%), Positives = 125/352 (35%), Gaps = 78/352 (22%)
Query: 10 SIALPLSVTADGCKDIFMKNEI------------LSASQPFAFNCTFPPITSGEVSVTWY 57
S + PL + K I ++E+ L+ + F C + + +TW
Sbjct: 7189 SASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTG--TAPIKITWA 7246
Query: 58 KNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCV---IKGRDSCHRIHVNLTVFE 114
K++ +I + + ++ + L + GD+G Y C I G+DSC L V E
Sbjct: 7247 KDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCS---AQLGVQE 7303
Query: 115 KHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLG-----PIKWYKDCNEIK 169
P + + + K D T + C +G + WYKD EI+
Sbjct: 7304 -----------PPRFIKKLEPSRIVKQDEFTRY-----ECKIGGSPEIKVLWYKDETEIQ 7347
Query: 170 GER-----FTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGG 224
F L + N+S ED G+Y C+A + S +
Sbjct: 7348 ESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEA------------HNAAGSASSSTSLKV 7395
Query: 225 SVPKIIYPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGV 284
P I K H IE G + ++C + T + V+ +Y + + +R G
Sbjct: 7396 KEPPIFRKKPHPIETLKGADVHLECELQGTPP------FHVS------WYKDKRELRSGK 7443
Query: 285 ETHVSFREHNLYTVNITFLEVKMEDYGLPFMCHA----GVSTAYIILQLPAP 332
+ + + +I L V D G + C A G T + L AP
Sbjct: 7444 KYKIMSEN---FLTSIHILNVDAADIG-EYQCKATNDVGSDTCVGSIALKAP 7491
Score = 42.0 bits (97), Expect = 0.002
Identities = 38/154 (24%), Positives = 66/154 (42%), Gaps = 18/154 (11%)
Query: 51 EVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPM-EWGDSGVYQCVIKGRDSCHRIHVN 109
+V+VTW K+ K+P K + +D+ L +P+ + DSG Y C
Sbjct: 3672 KVTVTWSKDGQKLPPGKDYKI-CFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSAT 3730
Query: 110 LTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIK 169
+TV E + + Y ++ G+ L C L K + + W+K+ E+
Sbjct: 3731 VTVREPP------SFVKKVDPSY--LMLPGESARLHCKL---KGSPVIQVTWFKNNKELS 3779
Query: 170 GER-----FTVLETRLLVSNVSAEDRGNYACQAI 198
F E L +++V ED G+Y+C+A+
Sbjct: 3780 ESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAV 3813
Score = 42.0 bits (97), Expect = 0.002
Identities = 46/214 (21%), Positives = 84/214 (39%), Gaps = 34/214 (15%)
Query: 49 SGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHV 108
S +S+ W+K+ +I S+ + H + ++ +E DSG Y C + ++
Sbjct: 4701 SHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSG 4760
Query: 109 NLTVFEKHWC---DTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDC 165
+LTV E + S PN + K + +G +T IKW+KD
Sbjct: 4761 HLTVKEPPYFVEKPQSQDVNPNTRVQLKAL--VGGTAPMT-------------IKWFKDN 4805
Query: 166 NEI-KGERFTV----LETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERA 220
E+ G +V T L + A D G Y CQ + N + + ++
Sbjct: 4806 KELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQ-----------LSNDVGTATSKAT 4854
Query: 221 GYGGSVPKIIYPKNHSIEVQLGTTLIVDCNVTDT 254
+ P+ I + + ++ G + +C +T T
Sbjct: 4855 LFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGT 4888
Score = 40.4 bits (93), Expect = 0.004
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 23/151 (15%)
Query: 51 EVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNL 110
E+ ++WYK + K+ S + I D + + D G Y+ V + ++ V
Sbjct: 8685 EIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLTVIE 8744
Query: 111 TVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIK- 169
+E+H D + L G+ ++TC P +W+++ +K
Sbjct: 8745 PAWERHLQDVT--------------LKEGQTCTMTCQFSVPNV----KSEWFRNGRILKP 8786
Query: 170 -GERFTVLE---TRLLVSNVSAEDRGNYACQ 196
G T +E +L +++V AED+G Y C+
Sbjct: 8787 QGRHKTEVEHKVHKLTIADVRAEDQGQYTCK 8817
Score = 39.3 bits (90), Expect = 0.010
Identities = 59/280 (21%), Positives = 108/280 (38%), Gaps = 53/280 (18%)
Query: 51 EVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVN- 109
E+ V+WYK +K+ + + + ++F ++ DSG Y C K +S + +
Sbjct: 7989 EIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYIC--KAENSVGEVSAST 8046
Query: 110 -LTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLG-----PIKWYK 163
LTV E+ L + + L +D T L C + + WYK
Sbjct: 8047 FLTVQEQ-----------KLPPSFSRQL---RDVQETVGLPVVFDCAISGSEPISVSWYK 8092
Query: 164 DCNEIKGER--FTVLETRLLVSNVSAEDR---GNYACQAILTHSGKQYEVLNGITVSITE 218
D +K T N+ DR G Y+C T + + + +TE
Sbjct: 8093 DGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSC----TATNPIGSASSSARLILTE 8148
Query: 219 RAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESK 278
G P + ++ +G + +C+VT T+ + + +S+
Sbjct: 8149 -----GKNPPFFDIRLAPVDAVVGESADFECHVTGTQ------------PIKVSWAKDSR 8191
Query: 279 RIREGVETHVSFREHNLYTVNITFLEVKMEDYGLPFMCHA 318
IR G + +S+ E+ + ++T L+V D G + C+A
Sbjct: 8192 EIRSGGKYQISYLEN---SAHLTVLKVDKGDSG-QYTCYA 8227
Score = 38.1 bits (87), Expect = 0.022
Identities = 63/267 (23%), Positives = 99/267 (37%), Gaps = 33/267 (12%)
Query: 14 PLSVTADGCKDIFMKNEILSASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRI 73
P VT G KD+ + + S TF T +++ W+K + ++
Sbjct: 4206 PSFVTKPGSKDVLPGSAVCLKS-------TFQGSTP--LTIRWFKGNKELVSGGSCYITK 4256
Query: 74 HQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYK 133
E+ + ++ DSG Y C + NL V E T + L E
Sbjct: 4257 EALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPA---TFVEKL-----EPS 4308
Query: 134 QILHLGKDDSLTCHLHFPKSCVLGPIK--WYKDCNEIKGE---RFTVLETR--LLVSNVS 186
Q+L G L C K PIK W+ + EIK R + +E+ L +++V
Sbjct: 4309 QLLKKGDATQLAC-----KVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVG 4363
Query: 187 AEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQLGTTLI 246
ED G Y C+A +G + V + E + I K + + +
Sbjct: 4364 IEDSGEYMCEA-QNEAGSDH---CSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGT 4419
Query: 247 VDCNVTDTKDNTNLRCWRVNNTLVDDY 273
+T KDNT LR R T + D+
Sbjct: 4420 PPFEITWFKDNTILRSGRKYKTFIQDH 4446
Score = 37.7 bits (86), Expect = 0.029
Identities = 34/155 (21%), Positives = 60/155 (38%), Gaps = 23/155 (14%)
Query: 47 ITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRI 106
++ + V W+KN ++ ++ + + I F + D+ + G S
Sbjct: 11952 LSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSS---- 12007
Query: 107 HVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDS-LTCHLHFPKSCVLGPIKWYKDC 165
LTV E G P + + + + KD+ L C + S P+KW+KD
Sbjct: 12008 EAKLTVLE---------GDPYFTGKLQDYTGVEKDEVILQCEI----SKADAPVKWFKDG 12054
Query: 166 NEIKGERFTVLET-----RLLVSNVSAEDRGNYAC 195
EIK + V++ L++ D G Y C
Sbjct: 12055 KEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC 12089
Score = 36.6 bits (83), Expect = 0.064
Identities = 36/158 (22%), Positives = 64/158 (40%), Gaps = 29/158 (18%)
Query: 49 SGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCV---IKGRDSCHR 105
S +SV W+++ ++I QS ++ + +E D+G+Y CV + G D C
Sbjct: 6767 SAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSA 6826
Query: 106 IHVNLTVFEK---HWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWY 162
+ LTV E S+ LP +S + ++ + +KW+
Sbjct: 6827 V---LTVQEPPSFEQTPDSVEVLPGMSLTFTSVI---------------RGTPPFKVKWF 6868
Query: 163 KDCNE-IKGERFTV----LETRLLVSNVSAEDRGNYAC 195
K E + GE + T L + V + G+Y+C
Sbjct: 6869 KGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSC 6906
Score = 33.1 bits (74), Expect = 0.71
Identities = 34/149 (22%), Positives = 63/149 (42%), Gaps = 21/149 (14%)
Query: 52 VSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLT 111
V++ W KN ++P + R+ + + + + D G Y V G+D +
Sbjct: 12762 VTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEY-IVTAGQDK--------S 12812
Query: 112 VFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIK-G 170
V E + + +L D Q + D +C L K+ +KWY++ EIK G
Sbjct: 12813 VAELLIIEAPTEFVEHLED---QTVTEFDDAVFSCQLSREKA----NVKWYRNGREIKEG 12865
Query: 171 ERFTVLET----RLLVSNVSAEDRGNYAC 195
+++ + RL++ + +D YAC
Sbjct: 12866 KKYKFEKDGSIHRLIIKDCRLDDECEYAC 12894
Score = 32.3 bits (72), Expect = 1.2
Identities = 34/153 (22%), Positives = 52/153 (33%), Gaps = 16/153 (10%)
Query: 51 EVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNL 110
E+ WYK+ + SK + + + F E DSG Y I
Sbjct: 4045 ELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTF 4104
Query: 111 TVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLG-PIKWYKDCNEI- 168
TV ++ L N+ TC L + L + W+KD EI
Sbjct: 4105 TVLDRDIAPFFTKPLRNVDSVVNG----------TCRLDCKIAGSLPMRVSWFKDGKEIA 4154
Query: 169 KGERFTVL----ETRLLVSNVSAEDRGNYACQA 197
+R+ + L + V D GN+ C+A
Sbjct: 4155 ASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRA 4187
Score = 32.3 bits (72), Expect = 1.2
Identities = 36/156 (23%), Positives = 60/156 (38%), Gaps = 25/156 (16%)
Query: 49 SGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCV---IKGRDSCHR 105
S +SV W+ +KI Q+ + + ++ D G Y CV + G D C
Sbjct: 5826 SSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRA 5885
Query: 106 IHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHL-GKDDSLTCHLHFPKSCVLGPIKWYKD 164
+ LTV E P+ E + + L GK+ + T + + + W++
Sbjct: 5886 V---LTVQEP----------PSFVKEPEPLEVLPGKNVTFTSVI---RGTPPFKVNWFRG 5929
Query: 165 CNE-IKGER----FTVLETRLLVSNVSAEDRGNYAC 195
E +KG+R F L + N+ G Y C
Sbjct: 5930 ARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTC 5965
Score = 32.0 bits (71), Expect = 1.6
Identities = 33/156 (21%), Positives = 58/156 (37%), Gaps = 21/156 (13%)
Query: 49 SGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHV 108
S E+ V W++N ++P S + I + DSG + C +
Sbjct: 5450 SPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCST 5509
Query: 109 NLTVFEKHWCDTSIGGLPNLSDEYKQILHLGK--DDSLTCHLHFPKSCVLGPIKWYKDCN 166
+ V E P + + I+ K + SL C L + WYKD
Sbjct: 5510 KVIVKE-----------PPVFSSFPPIVETLKNAEVSLECEL---SGTPPFEVVWYKDKR 5555
Query: 167 EIK-GERFTV----LETRLLVSNVSAEDRGNYACQA 197
+++ +++ + T + + NV D G Y C+A
Sbjct: 5556 QLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKA 5591
Score = 32.0 bits (71), Expect = 1.6
Identities = 41/168 (24%), Positives = 59/168 (35%), Gaps = 20/168 (11%)
Query: 37 PFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCV 96
P AF C S + V+WYK+ + +Q+ + + L + G Y C
Sbjct: 7132 PVAFECRING--SEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCS 7189
Query: 97 IKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVL 156
L + +H P D L LG+ + CH+
Sbjct: 7190 ASNPLGTASSSAKL-ILSEHEVPPFFDLKPVSVD-----LALGESGTFKCHV-----TGT 7238
Query: 157 GPIK--WYKDCNEIK---GERFTVLE--TRLLVSNVSAEDRGNYACQA 197
PIK W KD EI+ + T++E L V V D G Y C A
Sbjct: 7239 APIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYA 7286
Score = 31.6 bits (70), Expect = 2.1
Identities = 43/209 (20%), Positives = 79/209 (37%), Gaps = 34/209 (16%)
Query: 54 VTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIK---GRDSCHRIHVNL 110
+TW K++ +I + + L + GDSG Y C G+D C L
Sbjct: 6302 ITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCS---AQL 6358
Query: 111 TVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKG 170
+V E + E ++ G+ L C + + W+++ +E+
Sbjct: 6359 SVKEPPKFVKKL--------EASKVAKQGESIQLECKISGSPEI---KVSWFRNDSELHE 6407
Query: 171 E-----RFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGS 225
F L ++ SAED G+Y C+A H+G + ++T +A
Sbjct: 6408 SWKYNMSFINSVALLTINEASAEDSGDYICEA---HNGVGDA---SCSTALTVKA----- 6456
Query: 226 VPKIIYPKNHSIEVQLGTTLIVDCNVTDT 254
P + K + G+ +I+ C ++ T
Sbjct: 6457 -PPVFTQKPSPVGALKGSDVILQCEISGT 6484
Score = 31.2 bits (69), Expect = 2.7
Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 52 VSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVI---KGRDSC 103
+ VTW+KN+ ++ S ++ E + ++ DSG Y C G DSC
Sbjct: 3767 IQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSC 3821
Score = 31.2 bits (69), Expect = 2.7
Identities = 51/225 (22%), Positives = 90/225 (40%), Gaps = 33/225 (14%)
Query: 51 EVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNL 110
E++V+WYK +K+ + ++ + ++F + DSG Y C +
Sbjct: 6107 EITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVF 6166
Query: 111 TVFEKHWCDTSIGGLPNLSDEYKQILH-LGKDDSLTCHLHFPKSCVLGPIK--WYKDCNE 167
+ E+ P+ + + K I +G +LTC L+ PI+ WY+D
Sbjct: 6167 RIQERQL-------PPSFARQLKDIEQTVGLPVTLTCRLNGS-----APIQVCWYRDGVL 6214
Query: 168 IKGERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVP 227
++ + L+T V NV+ Q L+HSG+ + + + A P
Sbjct: 6215 LRDDE--NLQTS-FVDNVATLK----ILQTDLSHSGQYSCSASNPLGTASSSARLTAREP 6267
Query: 228 K---IIYPKNHSIEVQLGTTLIVDCNVTD--------TKDNTNLR 261
K K SI+V G + +C+VT +KDN +R
Sbjct: 6268 KKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIR 6312
Score = 31.2 bits (69), Expect = 2.7
Identities = 54/280 (19%), Positives = 103/280 (36%), Gaps = 53/280 (18%)
Query: 32 LSASQPFAFNCTF---PPITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWG 88
+ P T+ PPI SV+W K+ I S+ + + T + L
Sbjct: 6938 VETGSPIVLEATYTGTPPI-----SVSWIKDEYLISQSERCSITMTEKSTILEILESTIE 6992
Query: 89 DSGVYQCVIK---GRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLT 145
D Y C+I+ G+D C + ++V E + + E+ + + +G+ +L
Sbjct: 6993 DYAQYSCLIENEAGQDICEAL---VSVLEPPYFIEPL--------EHVEAV-IGEPATLQ 7040
Query: 146 CHLHFPKSCVLGPIKWYKDCNEIKGE-----RFTVLETRLLVSNVSAEDRGNYACQAILT 200
C + I WYK+ +++ +F L+++ V D G Y+C+A
Sbjct: 7041 CKVDGTPEI---RISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKA--- 7094
Query: 201 HSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNVTDTKDNTNL 260
V + + I R +P K + LG + +C + ++
Sbjct: 7095 -DNSVGAVASSAVLVIKAR-----KLPPFFARKLKDVHETLGFPVAFECRINGSE----- 7143
Query: 261 RCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYTVNI 300
L +Y + +++ SF HN+ T+ I
Sbjct: 7144 -------PLQVSWYKDGVLLKDDANLQTSF-VHNVATLQI 7175
Score = 31.2 bits (69), Expect = 2.7
Identities = 37/162 (22%), Positives = 61/162 (37%), Gaps = 30/162 (18%)
Query: 49 SGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIK---GRDSCHR 105
S ++V WYKN+ +I + + + + D+G+Y C + G C
Sbjct: 8276 SQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTS 8335
Query: 106 IHV-----NLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIK 160
V VF++H ++ EY Q L+CH+ + I+
Sbjct: 8336 SIVIKEPKKPPVFDQHLTPVTVS-----EGEYVQ---------LSCHVQGSEPI---RIQ 8378
Query: 161 WYKDCNEIKGE-----RFTVLETRLLVSNVSAEDRGNYACQA 197
W K EIK F L + +V+ D G+Y C+A
Sbjct: 8379 WLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKA 8420
Score = 30.8 bits (68), Expect = 3.5
Identities = 41/155 (26%), Positives = 62/155 (40%), Gaps = 29/155 (18%)
Query: 52 VSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIK---GRDSCHRIHV 108
+S W+K+ +I S + H+ + +E D+ Y C + G D+C I
Sbjct: 5266 ISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGI-- 5323
Query: 109 NLTVFEKHWCDTSIG---GLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDC 165
LTV E G +P+ + E+K IL K IKW+KD
Sbjct: 5324 -LTVKEPPSFLVKPGRQQAIPDSTVEFKAIL---------------KGTPPFKIKWFKDD 5367
Query: 166 NE-IKGER-FTVLE---TRLLVSNVSAEDRGNYAC 195
E + G + F LE + L + +V A G Y C
Sbjct: 5368 VELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTC 5402
Score = 30.4 bits (67), Expect = 4.6
Identities = 34/147 (23%), Positives = 58/147 (39%), Gaps = 17/147 (11%)
Query: 52 VSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLT 111
++VTW K+S +I I+ + + +E G Y C K R L+
Sbjct: 4515 ITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLS 4574
Query: 112 VFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIK-G 170
V E P E + + + D T + F + + KW+KD E+ G
Sbjct: 4575 VKE-----------PATITEEAVSIDVTQGDPATLQVKFSGTKEI-TAKWFKDGQELTLG 4622
Query: 171 ERF--TVLETRLLVSNVSAE--DRGNY 193
++ +V +T ++ +S E D G Y
Sbjct: 4623 SKYKISVTDTVSILKIISTEKKDSGEY 4649
Score = 29.6 bits (65), Expect = 7.9
Identities = 31/154 (20%), Positives = 60/154 (38%), Gaps = 13/154 (8%)
Query: 49 SGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHV 108
+G V W N ++ S+ + + + + D G+ C+ K ++ +
Sbjct: 33063 AGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQY 33122
Query: 109 NLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEI 168
+LT+ K D +S Q ++ G++ TC + S I+W+K+ I
Sbjct: 33123 DLTL-SKELSDAP----AFISQPRSQNINEGQNVLFTCEISGEPS---PEIEWFKNNLPI 33174
Query: 169 K-GERFTVLETR----LLVSNVSAEDRGNYACQA 197
++ +R L + N S D G Y +A
Sbjct: 33175 SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKA 33208
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 43.5 bits (101), Expect = 5e-04
Identities = 49/221 (22%), Positives = 93/221 (42%), Gaps = 33/221 (14%)
Query: 56 WYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEK 115
W KN + + + RI ++ + + D+G+YQC+ + + + L+V
Sbjct: 21 WLKNGEPL----LTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVI-- 74
Query: 116 HWCDTSIGGLPNLSDEYKQ---ILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIK-GE 171
++G P+ S + ++ +G + + C PK+ W K + +K E
Sbjct: 75 -----AVG--PDFSRTLLKRVTLVKVGGEVVIECK---PKASPKPVYTWKKGRDILKENE 124
Query: 172 RFTVLET-RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKII 230
R T+ E L + NV+ D G+Y C A H G N + T +++
Sbjct: 125 RITISEDGNLRIINVTKSDAGSYTCIAT-NHFGTASSTGNLVVKDPT----------RVM 173
Query: 231 YPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVD 271
P + S++V +G ++++ C VT + W N L+D
Sbjct: 174 VPPS-SMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLID 213
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 43.5 bits (101), Expect = 5e-04
Identities = 49/221 (22%), Positives = 93/221 (42%), Gaps = 33/221 (14%)
Query: 56 WYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEK 115
W KN + + + RI ++ + + D+G+YQC+ + + + L+V
Sbjct: 349 WLKNGEPL----LTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVI-- 402
Query: 116 HWCDTSIGGLPNLSDEYKQ---ILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIK-GE 171
++G P+ S + ++ +G + + C PK+ W K + +K E
Sbjct: 403 -----AVG--PDFSRTLLKRVTLVKVGGEVVIECK---PKASPKPVYTWKKGRDILKENE 452
Query: 172 RFTVLET-RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKII 230
R T+ E L + NV+ D G+Y C A H G N + T +++
Sbjct: 453 RITISEDGNLRIINVTKSDAGSYTCIAT-NHFGTASSTGNLVVKDPT----------RVM 501
Query: 231 YPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVD 271
P + S++V +G ++++ C VT + W N L+D
Sbjct: 502 VPPS-SMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLID 541
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 42.7 bits (99), Expect = 9e-04
Identities = 43/222 (19%), Positives = 87/222 (39%), Gaps = 33/222 (14%)
Query: 55 TWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFE 114
TW KN ++ + RI + ++ + DSGVYQC + + + L V
Sbjct: 350 TWLKNGERLNP----EERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRV-- 403
Query: 115 KHWCDTSIGGLPNLSD---EYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGE 171
+ P+ S + K + +G D + C P + I W + ++
Sbjct: 404 -------LASAPDFSKSPVKKKSFVQVGGDIVIGCK---PNAFPRAAISWKRGTETLRQS 453
Query: 172 R--FTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKI 229
+ F + + L + N++ D G+Y C A + + N ++ + ER +
Sbjct: 454 KRIFLLEDGSLKIYNITRSDAGSYTCIA----TNQFGTAKNTGSLIVKERT--------V 501
Query: 230 IYPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVD 271
I ++V +G ++++ C V+ + W N ++D
Sbjct: 502 ITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVID 543
>gi|38683840 CD96 antigen isoform 1 precursor [Homo sapiens]
Length = 585
Score = 42.4 bits (98), Expect = 0.001
Identities = 40/164 (24%), Positives = 63/164 (38%), Gaps = 26/164 (15%)
Query: 180 LLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEV 239
L + N+S G Y C +L G Q ++ N + + V + NH+IE+
Sbjct: 103 LHLRNMSCSVSGRYECMLVLYPEGIQTKIYNLLIQT---------HVTADEWNSNHTIEI 153
Query: 240 QLGTTLIVDC--NVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYT 297
++ TL + C N + + W V N+ D + SK I+E T + N
Sbjct: 154 EINQTLEIPCFQNSSSKISSEFTYAWSVENSSTDSWVLLSKGIKEDNGTQETLISQNHLI 213
Query: 298 VNITFLE---------------VKMEDYGLPFMCHAGVSTAYII 326
N T L+ V++ D G F CH V I+
Sbjct: 214 SNSTLLKDRVKLGTDYRLHLSPVQIFDDGRKFSCHIRVGPNKIL 257
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 41.6 bits (96), Expect = 0.002
Identities = 56/212 (26%), Positives = 86/212 (40%), Gaps = 31/212 (14%)
Query: 56 WYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSC-HRIHVNLTVFE 114
W+ N+ +PVS +Q + D + L + D G Y+C I+ + S H V L V
Sbjct: 356 WWVNNQSLPVSPRLQ--LSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVL- 412
Query: 115 KHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFT 174
+ D P +S Y G + SL+CH S W D N + +
Sbjct: 413 -YGPDD-----PTISPSYTYY-RPGVNLSLSCHA---ASNPPAQYSWLIDGNIQQHTQ-- 460
Query: 175 VLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKN 234
L +SN++ ++ G Y CQA + SG + ITVS +PK N
Sbjct: 461 ----ELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVS--------AELPKPSISSN 508
Query: 235 HSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVN 266
+S V+ + C + ++ T L W VN
Sbjct: 509 NSKPVEDKDAVAFTCE-PEAQNTTYL--WWVN 537
Score = 34.3 bits (77), Expect = 0.32
Identities = 56/253 (22%), Positives = 100/253 (39%), Gaps = 41/253 (16%)
Query: 16 SVTADGCKDIFMKNEILSASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQ 75
S++++ K + K+ + +P + T+ W+ N+ +PVS +Q +
Sbjct: 148 SISSNNSKPVEDKDAVAFTCEPETQDATY----------LWWVNNQSLPVSPRLQLS-NG 196
Query: 76 DETWILFLPMEWGDSGVYQCVIKGRDSCHRIH-VNLTVFEKHWCDTSIGGLPNLSDEYKQ 134
+ T LF + D+ Y+C + S R V L V T + L+ Y+
Sbjct: 197 NRTLTLF-NVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPT----ISPLNTSYRS 251
Query: 135 ILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETRLLVSNVSAEDRGNYA 194
G++ +L+CH S W+ + G F L + N++ + G+Y
Sbjct: 252 ----GENLNLSCHA---ASNPPAQYSWF-----VNGT-FQQSTQELFIPNITVNNSGSYT 298
Query: 195 CQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNVTDT 254
CQA + +G + ITV PK N+S V+ + + C +
Sbjct: 299 CQAHNSDTGLNRTTVTTITVY--------AEPPKPFITSNNSNPVEDEDAVALTCE-PEI 349
Query: 255 KDNTNLRCWRVNN 267
++ T L W VNN
Sbjct: 350 QNTTYL--WWVNN 360
Score = 34.3 bits (77), Expect = 0.32
Identities = 47/201 (23%), Positives = 82/201 (40%), Gaps = 30/201 (14%)
Query: 16 SVTADGCKDIFMKNEILSASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQ 75
S++++ K + K+ + +P A N T+ W+ N +PVS +Q +
Sbjct: 504 SISSNNSKPVEDKDAVAFTCEPEAQNTTY----------LWWVNGQSLPVSPRLQLS-NG 552
Query: 76 DETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQI 135
+ T LF + D+ Y C I+ S +R +T+ + DT I P+ S
Sbjct: 553 NRTLTLF-NVTRNDARAYVCGIQNSVSANRSDP-VTLDVLYGPDTPIISPPDSS------ 604
Query: 136 LHLGKDDSLTCHLHFPKSCVLGPIKWYK-DCNEIKGERFTVLETRLLVSNVSAEDRGNYA 194
G + +L+CH P Y N I + VL ++ ++ + G YA
Sbjct: 605 YLSGANLNLSCH------SASNPSPQYSWRINGIPQQHTQVL----FIAKITPNNNGTYA 654
Query: 195 CQAILTHSGKQYEVLNGITVS 215
C +G+ ++ ITVS
Sbjct: 655 CFVSNLATGRNNSIVKSITVS 675
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 40.8 bits (94), Expect = 0.003
Identities = 53/231 (22%), Positives = 91/231 (39%), Gaps = 35/231 (15%)
Query: 53 SVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTV 112
S W KN + + +++ R + + + DSG++QC+ + + L V
Sbjct: 348 SYRWLKNGAAL----VLEERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKV 403
Query: 113 FEKHWCDTSIGGLPNLSDEYKQIL---HLGKDDSLTCHLHFPKSCVLGPIKWYK-DCNEI 168
+ P+ S + L +G SL C P++ W K D +
Sbjct: 404 ---------VASAPDFSKNPMKKLVQVQVGSLVSLDCK---PRASPRALSSWKKGDVSVQ 451
Query: 169 KGERFTVL-ETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGIT-VSITERAGYGGSV 226
+ ER ++L + L ++NV+ D G Y C A Q+ NG T + +TE
Sbjct: 452 EHERISLLNDGGLKIANVTKADAGTYTCMA-----ENQFGKANGTTHLVVTE-------- 498
Query: 227 PKIIYPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDES 277
P I +++V +G ++I+ C V + W N L D D S
Sbjct: 499 PTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGS 549
Score = 32.3 bits (72), Expect = 1.2
Identities = 39/160 (24%), Positives = 65/160 (40%), Gaps = 13/160 (8%)
Query: 45 PPITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCH 104
PP SGE+S W N V + + + Q+ + +E D G Y CV+ +
Sbjct: 146 PPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTNA 205
Query: 105 RIHVNLTVFEKHWCDTSIGGL-PNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYK 163
R+ + T D +G P + ++ + L K ++ F + I W +
Sbjct: 206 RVLGSPTPLVLR-SDGVMGEYEPKIEVQFPETLPAAKGSTVKLEC-FALGNPIPQINWRR 263
Query: 164 D-----CNEIKGERFT-VLETRLLVSNVSAEDRGNYACQA 197
++IK +F+ VLE + N ED G+Y C A
Sbjct: 264 SDGLPFSSKIKLRKFSGVLE----IPNFQQEDAGSYECIA 299
Score = 31.6 bits (70), Expect = 2.1
Identities = 45/199 (22%), Positives = 78/199 (39%), Gaps = 34/199 (17%)
Query: 57 YKNSSKIPVSKIIQSRIHQDETWILFLP-MEWGDSGVYQCVIKGRDSCHRIHVNLTVFEK 115
++ S +P S I+ R +L +P + D+G Y+C+ + + LT + K
Sbjct: 261 WRRSDGLPFSSKIKLRKFSG---VLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAK 317
Query: 116 -HWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHF---PKSCVLGPIKWYKDCNEIKGE 171
HW + D + + +DSL PK +W K+ + E
Sbjct: 318 PHWVQL-------IKD-----VEIAVEDSLYWECRASGKPKPSY----RWLKNGAALVLE 361
Query: 172 RFTVLET-RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKII 230
T +E L +SN+S D G + C A E +G+ S E +
Sbjct: 362 ERTQIENGALTISNLSVTDSGMFQCIA---------ENKHGLVYSSAELKVVASAPDFSK 412
Query: 231 YPKNHSIEVQLGTTLIVDC 249
P ++VQ+G+ + +DC
Sbjct: 413 NPMKKLVQVQVGSLVSLDC 431
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 40.0 bits (92), Expect = 0.006
Identities = 63/290 (21%), Positives = 109/290 (37%), Gaps = 49/290 (16%)
Query: 51 EVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNL 110
+ V WYK+ ++ S + ++ + D G +QCV D C V +
Sbjct: 835 DAPVRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCV--AGDECAYFTVTI 892
Query: 111 TVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKG 170
T W G + + ++++ LTC L P + ++W KD E+
Sbjct: 893 TDVSS-WIVYPSGKVYVAAVRLERVV-------LTCELCRPWA----EVRWTKDGEEVVE 940
Query: 171 ERFTVLET-----RLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGS 225
+L+ RL++ V ED G Y C+ + TV++TE
Sbjct: 941 SPALLLQKEDTVRRLVLPAVQLEDSGEYLCEI--------DDESASFTVTVTE------P 986
Query: 226 VPKIIYPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGVE 285
+IIYP++ EV L + ++C V L C +Y + + E
Sbjct: 987 PVRIIYPRD---EVTL-IAVTLECVV--------LMCELSREDAPVRWYKDGLEVE---E 1031
Query: 286 THVSFREHNLYTVNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFR 335
+ E + + + ED G F+C AG +A+ + + AP R
Sbjct: 1032 SEALVLERDGPRCRLVLPAAQPEDGG-EFVCDAGDDSAFFTVTVTAPPER 1080
Score = 32.3 bits (72), Expect = 1.2
Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 9/64 (14%)
Query: 139 GKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETR-----LLVSNVSAEDRGNY 193
G D L HL P GP++WYKD + + LE L V + D G Y
Sbjct: 1284 GGDLELVVHLSGPG----GPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEY 1339
Query: 194 ACQA 197
C A
Sbjct: 1340 LCDA 1343
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 40.0 bits (92), Expect = 0.006
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 42/167 (25%)
Query: 161 WYKDCNEIKGERFTVL-----ETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVS 215
+++D +K RF +L E ++ ++NVS D G Y CQ ++ E ITV
Sbjct: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQ---LYTDPPQESYTTITV- 140
Query: 216 ITERAGYGGSVPKIIYPKNHSIEVQL-----GTTLIVDCNVTDTKDNTNLRCWRVNNTLV 270
++ P+N I++Q G + V+C +K T +R ++ N L
Sbjct: 141 -------------LVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTEL- 186
Query: 271 DDYYDESKRIREGVETHVSFREHNLYTV-NITFLEVKMEDYGLPFMC 316
+ + VE ++YTV + L+V ED G+P +C
Sbjct: 187 --------KGKSEVE-----EWSDMYTVTSQLMLKVHKEDDGVPVIC 220
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 40.0 bits (92), Expect = 0.006
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 42/167 (25%)
Query: 161 WYKDCNEIKGERFTVL-----ETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVS 215
+++D +K RF +L E ++ ++NVS D G Y CQ ++ E ITV
Sbjct: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQ---LYTDPPQESYTTITV- 140
Query: 216 ITERAGYGGSVPKIIYPKNHSIEVQL-----GTTLIVDCNVTDTKDNTNLRCWRVNNTLV 270
++ P+N I++Q G + V+C +K T +R ++ N L
Sbjct: 141 -------------LVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTEL- 186
Query: 271 DDYYDESKRIREGVETHVSFREHNLYTV-NITFLEVKMEDYGLPFMC 316
+ + VE ++YTV + L+V ED G+P +C
Sbjct: 187 --------KGKSEVE-----EWSDMYTVTSQLMLKVHKEDDGVPVIC 220
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 39.3 bits (90), Expect = 0.010
Identities = 55/232 (23%), Positives = 89/232 (38%), Gaps = 24/232 (10%)
Query: 32 LSASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFL-PMEWGDS 90
++ Q NC P VTW+K +PV HQ +L L DS
Sbjct: 2352 VAEGQTLDLNCVVPG--QSHAQVTWHKRGGSLPVR-------HQTHGSLLRLYQASPADS 2402
Query: 91 GVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQI-LHLGKDDSLTCHLH 149
G Y C + G V +T+ E ++G P + E + G+ L C +
Sbjct: 2403 GEYVCRVLGSSVPLEASVLVTI-EPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLV- 2460
Query: 150 FPKSCVLGPIKWYKDCNEIKGERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVL 209
+ W+K + R V +RL + V+ D G Y C+ + + ++ VL
Sbjct: 2461 --AGQAHAQVTWHKRGGSLPA-RHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVL 2517
Query: 210 NGITVSITERAGYGGSVPKIIYP---KNHSIEVQLGTTLIVDCNVTDTKDNT 258
V+I +R G + YP ++ S + G TL ++C V +T
Sbjct: 2518 ----VTIQQRLS-GSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHT 2564
Score = 38.5 bits (88), Expect = 0.017
Identities = 52/224 (23%), Positives = 84/224 (37%), Gaps = 26/224 (11%)
Query: 32 LSASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFL-PMEWGDS 90
++ Q NC P VTW+K +P HQ +L L + DS
Sbjct: 2163 VAEGQTLDLNCVVPG--QAHAQVTWHKRGGSLPAR-------HQTHGSLLRLHQVTPADS 2213
Query: 91 GVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSI--GGLPNLSDEYKQ-ILHLGKDDSLTCH 147
G Y C + G V +T+ + S+ G +P + E + G+ L+C
Sbjct: 2214 GEYVCHVVGTSGPLEASVLVTI------EASVIPGPIPPVRIESSSSTVAEGQTLDLSCV 2267
Query: 148 LHFPKSCVLGPIKWYKDCNEIKGERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYE 207
+ + WYK + R V +RL + S D G Y C+A +G +
Sbjct: 2268 V---AGQAHAQVTWYKRGGSLPA-RHQVRGSRLYIFQASPADAGQYVCRA---SNGMEAS 2320
Query: 208 VLNGITVSITERAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNV 251
+ +T + Y + I + S +V G TL ++C V
Sbjct: 2321 ITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVV 2364
Score = 36.2 bits (82), Expect = 0.084
Identities = 51/239 (21%), Positives = 84/239 (35%), Gaps = 27/239 (11%)
Query: 29 NEILSASQPFAFNCTFPPITSGEVS-------------VTWYKNSSKIPVSKIIQSRIHQ 75
+ + S S P + P + G+ +TWYK +P SR
Sbjct: 2623 SHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLP------SRHQT 2676
Query: 76 DETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQI 135
+ + M DSG Y C + ++V ++ G + E
Sbjct: 2677 HGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSS 2736
Query: 136 LHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETRLLVSNVSAEDRGNYAC 195
H+ + ++L + P + W+K + T +RL + +VS D G Y C
Sbjct: 2737 -HVAEGETLDLNCVVPGQAH-AQVTWHKRGGSLPSHHQT-RGSRLRLHHVSPADSGEYVC 2793
Query: 196 QAILTHSGKQYEVLNGITVSITERA---GYGGSVPKIIYPKNHSIEVQLGTTLIVDCNV 251
+ + + + VL I S + GG+ P I P S V G TL + C V
Sbjct: 2794 RVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPS--SSRVAEGQTLDLKCVV 2850
Score = 35.4 bits (80), Expect = 0.14
Identities = 42/200 (21%), Positives = 75/200 (37%), Gaps = 14/200 (7%)
Query: 53 SVTWYKNSSKIPVS-KIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLT 111
++TWYK +P +I+ SR+ + + DSG Y C + + +T
Sbjct: 2564 TITWYKRGGSLPSRHQIVGSRLRIPQ-------VTPADSGEYVCHVSNGAGSRETSLIVT 2616
Query: 112 VFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGE 171
+ P + + G+ L C + + I WYK +
Sbjct: 2617 IQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAI---ITWYKRGGSLPS- 2672
Query: 172 RFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIY 231
R + L + +S D G Y C+A + ++ ++ S + G S+P I
Sbjct: 2673 RHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMP--IR 2730
Query: 232 PKNHSIEVQLGTTLIVDCNV 251
++ S V G TL ++C V
Sbjct: 2731 IESSSSHVAEGETLDLNCVV 2750
Score = 32.0 bits (71), Expect = 1.6
Identities = 52/222 (23%), Positives = 81/222 (36%), Gaps = 31/222 (13%)
Query: 41 NCTFPPITSGEVSVTWYKNSSKIPV---SKIIQSRIHQDETWILFLPMEWGDSGVYQCVI 97
NC P VTW+K +P ++ + R+H + DSG Y C +
Sbjct: 2747 NCVVPG--QAHAQVTWHKRGGSLPSHHQTRGSRLRLHH---------VSPADSGEYVCRV 2795
Query: 98 KGRDSCHRIHVNLTVFEKHWCDTSI---GGLPNLSDEYKQILHLGKDDSLTCHLHFPKSC 154
G V +T+ + GG P + E + + +L P
Sbjct: 2796 MGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSS-RVAEGQTLDLKCVVPGQA 2854
Query: 155 VLGPIKWYKDCNEIKGERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITV 214
+ W+K + R V L ++ VS D G Y+CQ +T S E +V
Sbjct: 2855 H-AQVTWHKRGGNLPA-RHQVHGPLLRLNQVSPADSGEYSCQ--VTGSSGTLEA----SV 2906
Query: 215 SITERAGYGGSVP-----KIIYPKNHSIEVQLGTTLIVDCNV 251
+T G +P + IY + S V G TL ++C V
Sbjct: 2907 LVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVV 2948
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,467,725
Number of Sequences: 37866
Number of extensions: 1013468
Number of successful extensions: 2877
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 2353
Number of HSP's gapped (non-prelim): 530
length of query: 575
length of database: 18,247,518
effective HSP length: 108
effective length of query: 467
effective length of database: 14,157,990
effective search space: 6611781330
effective search space used: 6611781330
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.