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Search of human proteins with 28372509
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28372509 Ymer protein short isoform [Homo sapiens]
(306 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28372509 Ymer protein short isoform [Homo sapiens] 613 e-176
gi|41281911 Ymer protein long isoform [Homo sapiens] 334 7e-92
gi|4506467 radixin [Homo sapiens] 57 2e-08
gi|148746195 trichohyalin [Homo sapiens] 56 3e-08
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 54 2e-07
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 54 2e-07
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 54 2e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 54 2e-07
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 53 4e-07
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 51 1e-06
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 51 1e-06
gi|161702986 ezrin [Homo sapiens] 50 3e-06
gi|21614499 ezrin [Homo sapiens] 50 3e-06
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 50 3e-06
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 49 4e-06
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 49 4e-06
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 49 4e-06
gi|88759339 aster-associated protein [Homo sapiens] 49 4e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 49 6e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 49 6e-06
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 49 6e-06
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 49 7e-06
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 49 7e-06
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 48 9e-06
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 48 1e-05
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 47 2e-05
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 47 2e-05
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 47 2e-05
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 47 3e-05
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 47 3e-05
>gi|28372509 Ymer protein short isoform [Homo sapiens]
Length = 306
Score = 613 bits (1581), Expect = e-176
Identities = 306/306 (100%), Positives = 306/306 (100%)
Query: 1 MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK 60
MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK
Sbjct: 1 MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK 60
Query: 61 QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE 120
QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE
Sbjct: 61 QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE 120
Query: 121 LQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIAR 180
LQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIAR
Sbjct: 121 LQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIAR 180
Query: 181 KLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPK 240
KLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPK
Sbjct: 181 KLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPK 240
Query: 241 TAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHK 300
TAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHK
Sbjct: 241 TAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHK 300
Query: 301 GFHYKH 306
GFHYKH
Sbjct: 301 GFHYKH 306
>gi|41281911 Ymer protein long isoform [Homo sapiens]
Length = 482
Score = 334 bits (856), Expect = 7e-92
Identities = 163/185 (88%), Positives = 169/185 (91%)
Query: 122 QEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARK 181
Q E ++++H P P + + D GMKPRVMKEAVSTPSRMAHRDQEWYDAEIARK
Sbjct: 298 QGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARK 357
Query: 182 LQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKT 241
LQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKT
Sbjct: 358 LQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKT 417
Query: 242 AKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKG 301
AKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKG
Sbjct: 418 AKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKG 477
Query: 302 FHYKH 306
FHYKH
Sbjct: 478 FHYKH 482
Score = 300 bits (768), Expect = 1e-81
Identities = 182/332 (54%), Positives = 201/332 (60%), Gaps = 71/332 (21%)
Query: 1 MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK 60
MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK
Sbjct: 1 MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK 60
Query: 61 QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE 120
QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE
Sbjct: 61 QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKE 120
Query: 121 LQEEKKRKKHFPEFPATRAYADSYYYED----GGMKPRVMKEAVSTPSRMAHRDQEWYDA 176
LQEEKKRKKHFPEFPATRAYADSYYYED G + R + S P R
Sbjct: 121 LQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCR----------- 169
Query: 177 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQ-DP 235
+ + K K KE+ + L+ ++ +
Sbjct: 170 ---------------------------------LQRDGKTVKHKKEKPEHPLENLEEPEQ 196
Query: 236 EWKPKTAKAANSKSKESDEPH---------HSKNERPARPPPPIMT---------DGEDA 277
K + +++S K D PH S ERP RP P ++ D +
Sbjct: 197 HCSSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWET 256
Query: 278 DYTHFT-NQQSSTRH---FSKSESSHKGFHYK 305
H T N + +RH S S G H K
Sbjct: 257 KINHQTRNWEKQSRHQDRLSPKSSQKAGLHCK 288
Score = 45.4 bits (106), Expect = 6e-05
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
Query: 18 CRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRY 77
C++ DH + + + +L HD + ++ +E + +++ R
Sbjct: 287 CKEVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHR- 345
Query: 78 KDLEQQDCEIAQEIQEK--LAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKK 129
D E D EIA+++QE+ LA + + R Q +DE+IARLL +E + KK K+
Sbjct: 346 -DQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKE 398
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 57.0 bits (136), Expect = 2e-08
Identities = 61/252 (24%), Positives = 109/252 (43%), Gaps = 50/252 (19%)
Query: 54 HDLQVAKQ----LQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKD 109
H+L + ++ ++ + +KAQA+ +K K LE+ E E +++ E E+ RI+ +K+
Sbjct: 288 HELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLE--NEKKKREIAEKEKERIEREKE 345
Query: 110 EDIARLLQ--------EKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVS 161
E + RL Q +KEL+E+ ++ + RA ++ E + R +EA S
Sbjct: 346 ELMERLKQIEEQTIKAQKELEEQTRKALELDQ-ERKRAKEEAERLEK---ERRAAEEAKS 401
Query: 162 TPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAK 221
++ A A +++ +E LA ++ A++A EE KK K
Sbjct: 402 AIAKQA-----------ADQMKNQEQLAAELAEFTAKIALLEEA------------KKKK 438
Query: 222 EREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTH 281
E E + EW+ K A K +E + P PPPP++ E+ H
Sbjct: 439 EEEAT---------EWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEH 489
Query: 282 FTNQQSSTRHFS 293
N ++ S
Sbjct: 490 DENNAEASAELS 501
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 56.2 bits (134), Expect = 3e-08
Identities = 55/232 (23%), Positives = 105/232 (45%), Gaps = 21/232 (9%)
Query: 35 EQEIEHHLASNVQRNRLVQHDLQVAK----QLQEEDLKAQAQLQKRYKDLEQQ---DCEI 87
+QE E L ++ RL + + Q + Q +EE L + + +R ++LE+Q + E+
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 88 AQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYE 147
QE ++ L E E+RR QE++ + +E+ELQ+E+++ R + Y E
Sbjct: 1087 QQEEEQLLREEPEKRRRQERE----RQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
Query: 148 DGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIAR 207
+ ++ + P + ++ E E QEEE L +R Q + +E R
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQL-----LREEQEKRRQERER 1197
Query: 208 LLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANS-----KSKESDE 254
EE+ +K K+R + + +W+P+ A K +E+++
Sbjct: 1198 QYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQ 1249
Score = 52.0 bits (123), Expect = 7e-07
Identities = 51/258 (19%), Positives = 113/258 (43%), Gaps = 21/258 (8%)
Query: 15 KEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQ 74
+E R + E+ L+ QE+ Q+ + ++ + Q+ ++ +EE + Q + +
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 75 KRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEF 134
++ + EQQ+ Q++ RR QE++ E R QE+E +E++ R++ E
Sbjct: 323 EQQERREQQEERREQQL----------RREQEERREQQLRREQEEERREQQLRREQEEER 372
Query: 135 PATRAYADSYYYEDGGMK--------PRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEE 186
+ + + ++ ++ +E + R+Q+ + R+ QEEE
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432
Query: 187 L--LATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKA 244
+ + R ++ +++E R + E++ + +ER K L KR Q+ E + + K
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL-KRDQEEERRERWLKL 491
Query: 245 ANSKSKESDEPHHSKNER 262
+ +E E + R
Sbjct: 492 EEEERREQQERREQQLRR 509
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/217 (20%), Positives = 101/217 (46%), Gaps = 23/217 (10%)
Query: 60 KQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEK 119
+QL+EE Q + QKR ++Q+ E+A+ ++ E +R ++++DE++ R Q +
Sbjct: 127 RQLEEEP--GQRRRQKR----QEQERELAEGEEQSEKQERLEQRDRQRRDEELWR--QRQ 178
Query: 120 ELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKE------AVSTPSRMAHRD--- 170
E QE ++R+ + + + + + ++ ++ R + E R +D
Sbjct: 179 EWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVF 238
Query: 171 -----QEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREK 225
+EW E + +EEE L + R ++ ++EE R L +E + ++ +E+++
Sbjct: 239 QEEEEKEWRKRETVLR-KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ 297
Query: 226 SSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNER 262
L + +Q + + + + +E E + ER
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Score = 50.1 bits (118), Expect = 2e-06
Identities = 54/290 (18%), Positives = 135/290 (46%), Gaps = 38/290 (13%)
Query: 8 QSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRN----RLVQHDLQVAKQLQ 63
+ +L +E RD+ E+ T H + ++ + +R +L + + + ++ +
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR 503
Query: 64 EEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQE 123
E+ L+ + Q ++R + L++Q+ E + +Q++L E + RR QE++ E + + +EK L++
Sbjct: 504 EQQLRRE-QEERREQRLKRQEEE--ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Query: 124 EKK----------RKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRD--- 170
E++ R+ + R ++ ++ R+ +E V + R+
Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
Query: 171 ----------QEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLM------AEEK 214
Q+ +E + ++++L Q + R ++ ++EE RL EE+
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680
Query: 215 KAYKKAKEREKSSLDK-RKQDPEWKPKTAKAANSK-SKESDEPHHSKNER 262
+ + A+E ++ + ++ + + P+W+ + A+++ SK P + +R
Sbjct: 681 REQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQR 730
Score = 48.1 bits (113), Expect = 9e-06
Identities = 51/256 (19%), Positives = 113/256 (44%), Gaps = 31/256 (12%)
Query: 25 EDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQ- 83
E+ L +EQ++ H R+R + + Q+ ++ +E+ L+ Q + +++++ EQQ
Sbjct: 1648 EEPQLRRQEREQQLRH------DRDRKFREEEQLLQEGEEQQLRRQER-DRKFREEEQQL 1700
Query: 84 -----DCEIAQEIQEKLAIEAERR------RIQEKKDEDIARLLQEKELQEEKKRKKHFP 132
+ + QE Q+ E ER+ QE + E + R + +++ EE++ +
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
Query: 133 EFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQV 192
E R D + E+ ++ +E R D+++ + E R+ +EE+ L Q
Sbjct: 1761 EQQLRRQERDRKFREEEQLR----QEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQ- 1815
Query: 193 DMRAAQVAQDEEIARL------LMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAAN 246
R + +EE +L L E + Y+ ++ +R++ W+ + K
Sbjct: 1816 -QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ 1874
Query: 247 SKSKESDEPHHSKNER 262
+ ++ E H + ++
Sbjct: 1875 ERERKLREEHIRRQQK 1890
Score = 47.8 bits (112), Expect = 1e-05
Identities = 56/289 (19%), Positives = 121/289 (41%), Gaps = 48/289 (16%)
Query: 33 LQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQ 92
LQE++ QR + + +QL++E + Q Q+R + ++ ++ ++ Q
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 93 EKLAIEAERR-RIQE-------------KKDEDIARLLQEKELQEEKKRKKHFPEFPATR 138
E+ +E E++ R QE ++DE + + +E++L +++ +K E P R
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 139 AY-ADSYYYEDGGMKPR----VMKEAVSTPSRMAHRDQEWYD------------------ 175
+ D K R +++E R RD+++ +
Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE 1713
Query: 176 -----AEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDK 230
E+ RK +EEE L + + Q+ + E ++L E+ + ++ ++ + D+
Sbjct: 1714 QQLRRQELERKFREEEQLRQETEQE--QLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Query: 231 RKQDPEWKPKTAKAANSKSKESD----EPHHSKNERPARPPPPIMTDGE 275
+ ++ E + + +S+ESD E + ER + P DG+
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
Score = 46.6 bits (109), Expect = 3e-05
Identities = 47/228 (20%), Positives = 109/228 (47%), Gaps = 20/228 (8%)
Query: 47 QRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE------KLAIEAE 100
Q+ R + D ++ ++E K + L+K + L++++ + +E+QE KL +
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 101 RRRIQEKKDEDIARLLQEKEL---QEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMK 157
RR QE++ + RL +E++L QEE++R++ R + ++ + ++ +
Sbjct: 287 RRERQEEEQQQ-QRLRREQQLRRKQEEERREQQ----EERREQQERREQQEERREQQLRR 341
Query: 158 EAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAY 217
E + R+QE E + ++EE Q R Q+ +++++ R E++
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR-----EQQLR 396
Query: 218 KKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPAR 265
++ + R + L +R+Q + + + + ++ +E H K+E+ R
Sbjct: 397 REQQLRREQQL-RREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
Score = 46.2 bits (108), Expect = 4e-05
Identities = 54/212 (25%), Positives = 97/212 (45%), Gaps = 39/212 (18%)
Query: 62 LQEEDLKAQAQLQKRYKDLEQQDC---------EIAQEIQEK---LAIEAERRRIQEKKD 109
L EE+ K Q + Q+R ++ E Q E AQ++QE+ L + ERRR QE++
Sbjct: 811 LPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR 870
Query: 110 EDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHR 169
+ R +L+EE+KR++H YA E + ++++E R
Sbjct: 871 DQKWRW----QLEEERKRRRH-------TLYAKPALQEQLRKEQQLLQEEEEELQREERE 919
Query: 170 DQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLD 229
+ + E R+ +EEE Q+ Q+EE +LL E +K ++ +ER+ D
Sbjct: 920 KRRRQEQE--RQYREEE-----------QLQQEEE--QLLREEREKRRRQERERQYRK-D 963
Query: 230 KRKQDPEWKPKTAKAANSKSKESDEPHHSKNE 261
K+ Q E + + + +E ++ + + E
Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEE 995
Score = 45.8 bits (107), Expect = 5e-05
Identities = 57/256 (22%), Positives = 117/256 (45%), Gaps = 29/256 (11%)
Query: 24 LEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEE------DLKAQAQLQKRY 77
L+ A LQE+E +R++ + D + QL+EE L A+ LQ++
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 78 KDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPAT 137
+ +Q E +E+Q + E E+RR QE++ + +E++LQ+E+++
Sbjct: 900 RKEQQLLQEEEEELQRE---EREKRRRQEQERQ----YREEEQLQQEEEQLLREEREKRR 952
Query: 138 RAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQE-WYDAEIARKLQEEELLATQVDMRA 196
R + Y +D ++ + + P + +++E Y E + +EE+LL + + R
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Query: 197 AQ-----------VAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAA 245
Q + Q+EE +LL E +K ++ +ERE+ ++ + E + +
Sbjct: 1013 RQEWERQYRKKDELQQEEE--QLLREEREK--RRLQERERQYREEEELQQEEEQLLGEER 1068
Query: 246 NSKSKESDEPHHSKNE 261
++ ++ E + K E
Sbjct: 1069 ETRRRQELERQYRKEE 1084
Score = 44.3 bits (103), Expect = 1e-04
Identities = 43/174 (24%), Positives = 78/174 (44%), Gaps = 26/174 (14%)
Query: 67 LKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKK 126
L+ Q + Q R ++ +Q++ E +EK E+RR Q ++ E + L+E+E + ++
Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEK-----EQRRRQRREREKELQFLEEEEQLQRRE 844
Query: 127 RKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEW-YDAEIARKLQEE 185
R + E EDG + ++ S+ RDQ+W + E RK +
Sbjct: 845 RAQQLQE------------EEDG-----LQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Query: 186 ELL---ATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 236
L A Q +R Q EE L E +K ++ +ER+ ++ +Q+ E
Sbjct: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEE 941
Score = 43.1 bits (100), Expect = 3e-04
Identities = 56/232 (24%), Positives = 112/232 (48%), Gaps = 29/232 (12%)
Query: 35 EQEIEHHLASNVQRNRLVQHDLQVAK----QLQEEDLKAQAQLQKRYKDLEQQ---DCEI 87
+QE E L ++ R + + Q K Q +EE L + + ++R ++ E+Q + E+
Sbjct: 997 QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEEL 1056
Query: 88 AQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR-KKHFPEFPATRAYADSYYY 146
QE ++ L E E RR QE + + +E+ELQ+E+++ + PE R +
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQ----YRKEEELQQEEEQLLREEPE-KRRRQERERQCR 1111
Query: 147 EDGGMKPRVMKEAVSTPSRMAHRDQE---WYDAEIARKLQEEELLATQVDMR-----AAQ 198
E+ ++ +E + R R QE Y E + +EE+LL + + R Q
Sbjct: 1112 EEEELQQE--EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQ 1169
Query: 199 VAQDEEIAR---LLMAEEKKAYKKAKE---REKSSLDKRKQDPEWKPKTAKA 244
++EE+ + L+ EE++ ++ +E RE+ L ++K+ ++ + ++
Sbjct: 1170 YREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Score = 43.1 bits (100), Expect = 3e-04
Identities = 46/229 (20%), Positives = 107/229 (46%), Gaps = 27/229 (11%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE 93
+E E L + R+R Q DLQ L E+ + + Q ++R+ +Q+D +E Q
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQ--HLLGEQQERDREQERRRW---QQRDRHFPEEEQL 1299
Query: 94 KLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKP 153
+ + E +R +++K ++ +LL+E+ +EEK+R++ D + E+
Sbjct: 1300 EREEQKEAKR-RDRKSQEEKQLLREE--REEKRRRQE----------TDRKFREE----E 1342
Query: 154 RVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEE 213
++++E P R RD+++ + E+ + Q + L + +R + E + L E+
Sbjct: 1343 QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR-----RQERERKFLKEEQ 1397
Query: 214 KKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNER 262
+ ++ +++ + D++ ++ E + + +E + + ER
Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Score = 42.7 bits (99), Expect = 4e-04
Identities = 39/208 (18%), Positives = 96/208 (46%), Gaps = 23/208 (11%)
Query: 33 LQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKD--LEQQDCEIAQE 90
L+ QE E Q+ R + + Q+ + + + + QL ++ +D +++ ++ ++
Sbjct: 1383 LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ 1442
Query: 91 IQEKLAIEAERRRIQEK--KDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYED 148
+E+ +E E++ QE+ K + +LLQE+E Q+ ++++ D + E+
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQER------------DRKFLEE 1490
Query: 149 GGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARL 208
R ++ R+QE E RK EEE + + + +++++ R
Sbjct: 1491 EQQLRRQERDR-------KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1543
Query: 209 LMAEEKKAYKKAKEREKSSLDKRKQDPE 236
++++ + K RE+ L + +++ +
Sbjct: 1544 ERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Score = 42.4 bits (98), Expect = 5e-04
Identities = 52/284 (18%), Positives = 125/284 (44%), Gaps = 44/284 (15%)
Query: 21 FAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQL---QEEDLKAQAQLQKRY 77
F LED L +Q+++H L +R+R + + +EE L+ + Q + +
Sbjct: 1250 FRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR 1309
Query: 78 KDLEQQDCE--IAQEIQEKLA-------IEAERRRIQEKKDEDIAR-------------- 114
+D + Q+ + + +E +EK E + +QE++++ + R
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH 1369
Query: 115 -------LLQEKELQEEKKRKKHFPEFPATRAY-ADSYYYEDGGMKPRVMKEAVSTPSRM 166
L +E+ L+ +++ +K E R + +D K R ++ +S R
Sbjct: 1370 QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429
Query: 167 AHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLM-AEEKKAYKKAKER-- 223
+E + ++ R+ +E + L + +R + + E +LL EE++ +++ ++R
Sbjct: 1430 RKFREE--EQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKF 1487
Query: 224 --EKSSLDKRKQDPEWKPKTAKAANSKSK---ESDEPHHSKNER 262
E+ L ++++D +++ + ++ + K E + H + +R
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
Score = 40.4 bits (93), Expect = 0.002
Identities = 49/244 (20%), Positives = 111/244 (45%), Gaps = 30/244 (12%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQ-----VAKQLQE----EDLKAQAQLQKRYKDLEQQD 84
QE+E+ + ++ RL Q D Q + +Q QE E+ +A+ + + K E ++
Sbjct: 144 QERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE 203
Query: 85 CEIAQEIQEKLAIEAERRRIQEKKD---EDIARLLQEKELQEEKKRKKHFPEFPATRAYA 141
++++ + +E R+ +EK+ E R+ QE+E +E +KR+ R
Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRE------TVLRKEE 257
Query: 142 DSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQ 201
+ E+ P+ +E ++ +++ E+ R+ QEEE ++ R Q+ +
Sbjct: 258 EKLQEEE----PQRQRELQEEEEQLRKLERQ----ELRRERQEEEQQQQRL-RREQQLRR 308
Query: 202 DEEIARLLMAEEKKAYKKAKEREKSSLD---KRKQDPEWKPKTAKAANSKSKESDEPHHS 258
+E R EE++ ++ +E+++ + +R+Q+ + + + + +E
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 259 KNER 262
+ ER
Sbjct: 369 EEER 372
Score = 40.0 bits (92), Expect = 0.003
Identities = 48/235 (20%), Positives = 107/235 (45%), Gaps = 25/235 (10%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE 93
+E+E++ ++ + ++ +Q +EE+ +L+Q++ ++ +E QE
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEE------------ELQQEEEQLLREEQE 1189
Query: 94 KLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRK--KHFPEFPATRAYADSYYYEDGGM 151
K E ER Q +++E++ R +++ ++E +R K E A D+ Y G
Sbjct: 1190 KRRQERER---QYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 152 KPRVMK-EAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLM 210
+ + E R + +D + E + +E+E Q R ++E++ R
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQ--QRDRHFPEEEQLEREEQ 1304
Query: 211 AEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPAR 265
E K+ +K++E EK L + +++ + +T + K +E ++ + E+P R
Sbjct: 1305 KEAKRRDRKSQE-EKQLLREEREEKRRRQET----DRKFREEEQLLQEREEQPLR 1354
Score = 32.0 bits (71), Expect = 0.70
Identities = 27/132 (20%), Positives = 65/132 (49%), Gaps = 31/132 (23%)
Query: 23 VLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQ 82
+LE+ L +EQ++ +R+R + + Q+ ++ +E+ L++Q + +++++ EQ
Sbjct: 1749 ILEEEQLRPEREEQQLRRQ-----ERDRKFREEEQLRQEREEQQLRSQ-ESDRKFREEEQ 1802
Query: 83 QDCEIAQEI-------------QEKLAIEAERRRIQEKKD------------EDIARLLQ 117
E ++ +E+L +E + +R+++++D E R Q
Sbjct: 1803 LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQ 1862
Query: 118 EKELQEEKKRKK 129
E +EE+KR++
Sbjct: 1863 ELWQEEEQKRRQ 1874
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 53.9 bits (128), Expect = 2e-07
Identities = 60/254 (23%), Positives = 111/254 (43%), Gaps = 39/254 (15%)
Query: 19 RDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQL-QKRY 77
RD +LE + L +E V+R + +Q ++ ++ +EE ++ + Q+ ++
Sbjct: 207 RDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQME 266
Query: 78 KDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEK-ELQEEKKR-----KKHF 131
K+ E++ Q QEK + ++QE+ +D+ R Q+K ++Q E KR +K
Sbjct: 267 KNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQK 326
Query: 132 PEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQ 191
E A AD E T +MA + ++AE R +E+E
Sbjct: 327 AELLAQEKLADQMVME-------------FTKKKMAREAE--FEAEQERIRREKE----- 366
Query: 192 VDMRAAQVAQDEEIARL-LMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSK 250
+EIARL M E+ + Y+ ++ ++ ++ D EW+ K + A K +
Sbjct: 367 -----------KEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKME 415
Query: 251 ESDEPHHSKNERPA 264
E S+ E+ A
Sbjct: 416 TEAELRKSRLEQVA 429
Score = 49.7 bits (117), Expect = 3e-06
Identities = 61/232 (26%), Positives = 102/232 (43%), Gaps = 62/232 (26%)
Query: 25 EDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQD 84
E+ +L +EQE E L Q L + DL+ ++ Q++ LK QA++++ + ++Q
Sbjct: 270 EERSLLAEQREQEKEQMLEYMEQ---LQEEDLKDMERRQQQKLKMQAEIKRINDENQKQK 326
Query: 85 CEIAQEIQEKLA-----------------IEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
E+ QEKLA EAE+ RI+ +K+++IARL + +QE+
Sbjct: 327 AELLA--QEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARL---RAMQEK--- 378
Query: 128 KKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYD--AEIARKLQEE 185
A Y E ++ + +E D+EW E ARK E
Sbjct: 379 -------------AQDYQAEQDALRAKRNQEVA---------DREWRRKEKENARKKMET 416
Query: 186 EL---------LATQVDMRAAQVAQD-EEIARLLMAEEKKAYKKAKEREKSS 227
E +A + A QV +D +E R+L A+ ++ K+ E EK +
Sbjct: 417 EAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKA 468
Score = 39.7 bits (91), Expect = 0.003
Identities = 34/102 (33%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Query: 39 EHHLASNVQRNR------LVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQ-EI 91
EH LA VQR+R L Q+ K+ EE+ KA +LQ +L +Q E Q E+
Sbjct: 432 EHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHA-NELRRQVRENQQKEV 490
Query: 92 QEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPE 133
Q ++A E RR++E+ + R+ + K + E+ R PE
Sbjct: 491 QNRIATFEEGRRLKEEAQKRRERIDEIKRKKLEELRATGLPE 532
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 53.5 bits (127), Expect = 2e-07
Identities = 73/299 (24%), Positives = 129/299 (43%), Gaps = 38/299 (12%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
+ Q+R K+L +QQ+ E + +E++ E ERRR E + E I R L+E++ Q E +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRR-AEHEQEYIRRQLEEEQRQLEILQ 462
Query: 128 KKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEE- 186
++ E Y K + ++E R A R + R+L++E
Sbjct: 463 QQLLHEQALLLEY-----------KRKQLEE-----QRQAER--------LQRQLKQERD 498
Query: 187 -LLATQVDMRAAQVAQDEEIARL---LMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTA 242
L++ Q + + + + + + EK A+ AKE E+ S R+ P K A
Sbjct: 499 YLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAW--AKEVEERSRLNRQSSPAMPHKVA 556
Query: 243 -KAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHK 300
+ ++ E +PAR PP M D H +S + S+S H+
Sbjct: 557 NRISDPNLPPRSESFSISGVQPARTPP--MLRPVDPQIPHLVAVKSQGPALTASQSVHE 613
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 53.5 bits (127), Expect = 2e-07
Identities = 73/299 (24%), Positives = 129/299 (43%), Gaps = 38/299 (12%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
+ Q+R K+L +QQ+ E + +E++ E ERRR E + E I R L+E++ Q E +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRR-AEHEQEYIRRQLEEEQRQLEILQ 462
Query: 128 KKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEE- 186
++ E Y K + ++E R A R + R+L++E
Sbjct: 463 QQLLHEQALLLEY-----------KRKQLEE-----QRQAER--------LQRQLKQERD 498
Query: 187 -LLATQVDMRAAQVAQDEEIARL---LMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTA 242
L++ Q + + + + + + EK A+ AKE E+ S R+ P K A
Sbjct: 499 YLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAW--AKEVEERSRLNRQSSPAMPHKVA 556
Query: 243 -KAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHK 300
+ ++ E +PAR PP M D H +S + S+S H+
Sbjct: 557 NRISDPNLPPRSESFSISGVQPARTPP--MLRPVDPQIPHLVAVKSQGPALTASQSVHE 613
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 53.5 bits (127), Expect = 2e-07
Identities = 49/228 (21%), Positives = 104/228 (45%), Gaps = 14/228 (6%)
Query: 46 VQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEI------AQEIQEKLAIEA 99
VQRN+++ + + + +K L+ K+ E+Q E A++++ + E
Sbjct: 499 VQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEED 558
Query: 100 ERRRIQE---KKDEDIARLLQEKELQE---EKKRKKHFPEFPATRAYADSYYYEDGGMKP 153
+RRR++E K++E + ++LQ +E E E+K+K+ +F + E +
Sbjct: 559 KRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEK 618
Query: 154 RVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEE 213
K A + R ++ +A R LQ+EE ++ Q ++EE RL A E
Sbjct: 619 AKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL--LQKKKEEEQERLRKAAE 676
Query: 214 KKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNE 261
K + +E+E+ ++R+Q+ + + + + ++ E + +
Sbjct: 677 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 724
Score = 48.9 bits (115), Expect = 6e-06
Identities = 53/238 (22%), Positives = 110/238 (46%), Gaps = 22/238 (9%)
Query: 30 AHSLQEQEIEHHLASNVQRNRLVQHD-----LQVAKQLQEEDLKAQAQLQKRYKDLEQQ- 83
A L+ Q++E ++ +L + + LQ +++++ + + Q+++++ ++++
Sbjct: 547 AEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKT 606
Query: 84 ----DCEIAQEIQEKLAI-----EAERRRIQEKKDEDIARLLQEKE---LQEEKKRKKHF 131
+ +A+E +K A E E RR QE++ + L QE+E QE ++KK
Sbjct: 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 666
Query: 132 PEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQ 191
+ +A E + R + R+QE + E R+L E+E Q
Sbjct: 667 EQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE--RQLAEQERRREQ 724
Query: 192 VDMRAAQVAQDEEIARLLMAE--EKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANS 247
++A + Q+ E A L E +++ +K K+ E+ L +R+ E + K +AA +
Sbjct: 725 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGA 782
Score = 44.3 bits (103), Expect = 1e-04
Identities = 47/229 (20%), Positives = 106/229 (46%), Gaps = 27/229 (11%)
Query: 2 AEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQV--A 59
A ++Q K K++ + FA +++ T E+ E LA + + ++ A
Sbjct: 580 ARERVEQMKEEKKKQIEQKFAQIDEKT------EKAKEERLAEEKAKKKAAAKKMEEVEA 633
Query: 60 KQLQEEDLKAQAQLQKRYKDLEQQDC--EIAQEIQEKLAIEAERRRIQEKKDEDIARLLQ 117
++ QEE+ + LQ+ ++ Q+ + +E QE+L AE +R+ E+++++ +
Sbjct: 634 RRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQE----RR 689
Query: 118 EKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAE 177
E+E +E+++R++ E E + ++ ++ ++E + E
Sbjct: 690 EQERREQERREQERRE------------QERREQERQLAEQERRREQERLQAERELQERE 737
Query: 178 IARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKS 226
A +LQ+E+ L +++ + + Q R L E++K K+A K+
Sbjct: 738 KALRLQKEQ-LQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 785
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 52.8 bits (125), Expect = 4e-07
Identities = 55/233 (23%), Positives = 104/233 (44%), Gaps = 20/233 (8%)
Query: 59 AKQLQEEDLKAQ--AQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLL 116
++ L + LK+Q A+L K+ K EQ++ + E EK E + R+ ++ K+E+ R
Sbjct: 650 SRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEE-ERKR 708
Query: 117 QEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDA 176
QE+ ++ ++R+ P+ PA + + + + G +M +V R+ + ++
Sbjct: 709 QEEIERQRRERRYILPDEPAIIVHPN-WAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEV 767
Query: 177 EIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPE 236
+ +L E L R V + + L E+KK K ++++ K ++D E
Sbjct: 768 SLFAELFNEML------QRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDE 821
Query: 237 W---KPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQ 286
KPK K+ + K K+ D K ++ D +D D T N Q
Sbjct: 822 TDEPKPKRRKSGDDKDKKEDRDERKKEDKR-------KDDSKDDDETEEDNNQ 867
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 50.8 bits (120), Expect = 1e-06
Identities = 67/296 (22%), Positives = 123/296 (41%), Gaps = 23/296 (7%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRI---QEKKDEDIARLLQEKELQEE 124
+ Q+R K+L +QQ+ E + +E++ E ERRR QE K + + Q + LQ +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQ 463
Query: 125 KKRKK-------HFPEFPATRAYADSYYYEDG---GMKPRVMKEAVSTPSRMAHRDQEWY 174
K+++ H + Y+Y++G KP KE V SR+ +
Sbjct: 464 LKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE-VEERSRLNRQSSPAM 522
Query: 175 DAEIARKLQEEEL--LATQVDMRAAQVAQDEEIARLL--MAEEKKAYKKAKEREKSSLDK 230
++A ++ + L + + Q A+ + R + A K +S
Sbjct: 523 PHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALTASQSV 582
Query: 231 RKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQ 286
+Q + +A N S + P +N P PP+ T E D + + Q+
Sbjct: 583 HEQPTKGLSGFQEALNVTSHRVEMPR--QNSDPTSENPPLPTRIEKFDRSSWLRQE 636
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 50.8 bits (120), Expect = 1e-06
Identities = 67/296 (22%), Positives = 123/296 (41%), Gaps = 23/296 (7%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRI---QEKKDEDIARLLQEKELQEE 124
+ Q+R K+L +QQ+ E + +E++ E ERRR QE K + + Q + LQ +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQ 463
Query: 125 KKRKK-------HFPEFPATRAYADSYYYEDG---GMKPRVMKEAVSTPSRMAHRDQEWY 174
K+++ H + Y+Y++G KP KE V SR+ +
Sbjct: 464 LKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE-VEERSRLNRQSSPAM 522
Query: 175 DAEIARKLQEEEL--LATQVDMRAAQVAQDEEIARLL--MAEEKKAYKKAKEREKSSLDK 230
++A ++ + L + + Q A+ + R + A K +S
Sbjct: 523 PHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALTASQSV 582
Query: 231 RKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQ 286
+Q + +A N S + P +N P PP+ T E D + + Q+
Sbjct: 583 HEQPTKGLSGFQEALNVTSHRVEMPR--QNSDPTSENPPLPTRIEKFDRSSWLRQE 636
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 49.7 bits (117), Expect = 3e-06
Identities = 48/223 (21%), Positives = 98/223 (43%), Gaps = 39/223 (17%)
Query: 54 HDLQVAKQ----LQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKD 109
H+L + ++ ++ + +KAQA+ +K K LE+Q E ++ +E +E E+ ++ +K+
Sbjct: 288 HELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRE--TVEREKEQMMREKE 345
Query: 110 EDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHR 169
E + RL +E ++ +R+ + + E+ + + E + A R
Sbjct: 346 ELMLRLQDYEEKTKKAERE-------LSEQIQRALQLEEERKRAQEEAERLEADRMAALR 398
Query: 170 DQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLD 229
+E + + +++ +E LA ++ A++A EE R
Sbjct: 399 AKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARR---------------------- 436
Query: 230 KRKQDP--EWKPKTAKAANSKSKESDEPHHSKNERPARPPPPI 270
RK+D EW+ + +A + K +E H P PPPP+
Sbjct: 437 -RKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPP-PPPPV 477
Score = 36.2 bits (82), Expect = 0.037
Identities = 23/99 (23%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQ----DCEIAQ 89
Q +E +H Q+ + + ++ +E+ ++ + +L R +D E++ + E+++
Sbjct: 308 QAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSE 367
Query: 90 EIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRK 128
+IQ L +E ER+R QE+ + A + +EE +R+
Sbjct: 368 QIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQ 406
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 49.7 bits (117), Expect = 3e-06
Identities = 48/223 (21%), Positives = 98/223 (43%), Gaps = 39/223 (17%)
Query: 54 HDLQVAKQ----LQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKD 109
H+L + ++ ++ + +KAQA+ +K K LE+Q E ++ +E +E E+ ++ +K+
Sbjct: 288 HELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRE--TVEREKEQMMREKE 345
Query: 110 EDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHR 169
E + RL +E ++ +R+ + + E+ + + E + A R
Sbjct: 346 ELMLRLQDYEEKTKKAERE-------LSEQIQRALQLEEERKRAQEEAERLEADRMAALR 398
Query: 170 DQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLD 229
+E + + +++ +E LA ++ A++A EE R
Sbjct: 399 AKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARR---------------------- 436
Query: 230 KRKQDP--EWKPKTAKAANSKSKESDEPHHSKNERPARPPPPI 270
RK+D EW+ + +A + K +E H P PPPP+
Sbjct: 437 -RKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPP-PPPPV 477
Score = 36.2 bits (82), Expect = 0.037
Identities = 23/99 (23%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQ----DCEIAQ 89
Q +E +H Q+ + + ++ +E+ ++ + +L R +D E++ + E+++
Sbjct: 308 QAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSE 367
Query: 90 EIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRK 128
+IQ L +E ER+R QE+ + A + +EE +R+
Sbjct: 368 QIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQ 406
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 49.7 bits (117), Expect = 3e-06
Identities = 53/224 (23%), Positives = 105/224 (46%), Gaps = 28/224 (12%)
Query: 30 AHSLQEQEIEHHLASNVQ-RNRLVQHDLQVAKQLQEEDLKAQAQ---LQKRYKDLEQQDC 85
AH LQE+E +H LA +N +H +A++ E+ K + + +Q+ ++LEQ++
Sbjct: 540 AHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREA 599
Query: 86 EIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPAT----RAYA 141
E+ +K+ E R QE K+ + R+LQE E ++K ++ + T +A+
Sbjct: 600 EL-----QKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFK 654
Query: 142 DSYYYEDGGMKP---------RVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQV 192
D + + P ++ KE R+ +++++ E A++L+E L+ +
Sbjct: 655 DIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAY 714
Query: 193 DMRAAQ-----VAQDEEIARLLMAEEKKAYKKAKEREKSSLDKR 231
+ + + Q+EE + E +KA + K R L+ R
Sbjct: 715 EEQRIKDMDLWEQQEEERITTMQLEREKALEH-KNRMSRMLEDR 757
Score = 46.2 bits (108), Expect = 4e-05
Identities = 56/256 (21%), Positives = 115/256 (44%), Gaps = 45/256 (17%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDL---KAQAQLQKRYKD-LEQQDCEIAQ 89
++QE E ++R + ++H ++++ L++ DL + +A Q Y++ L+Q + +A+
Sbjct: 726 EQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAE 785
Query: 90 EIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDG 149
E +L E R+ Q K++ R+ +E +EE++R+ E+
Sbjct: 786 ERHNRL----EERKRQRKEER---RITYYREKEEEEQRRA-----------------EEQ 821
Query: 150 GMKPRVMKEAVSTPSRMAHRDQEWYD-AEIARKLQEEELLATQVDMRAAQVAQDEEIARL 208
+K R +E + A R++E + E +KL+E E Q ++ + + E R
Sbjct: 822 MLKEREERER----AERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERR 877
Query: 209 LMAEEKKAYKKAKEREKSSLDKRKQDP----EWK--PKTAKAANSKSKESDEPHHSKNER 262
L + + K ++ ++ S ++ P EW+ P + + ++ D H ER
Sbjct: 878 L-GDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEER 936
Query: 263 PARPPPPIMTDGEDAD 278
P R + D ED +
Sbjct: 937 PRR-----LGDDEDRE 947
Score = 36.6 bits (83), Expect = 0.029
Identities = 49/253 (19%), Positives = 111/253 (43%), Gaps = 33/253 (13%)
Query: 35 EQEIEHHLASNVQRNR--LVQHD--LQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQE 90
E+ E + N+QR + L Q + LQ ++ +EE L+ +A+ +++ + L++ + +
Sbjct: 576 EERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKT 635
Query: 91 IQEKL-AIEAERRRIQEKKDEDIARL-------LQEKELQEEKKRKKHFPEFPATRAYAD 142
++E+L I+ + KD DI L + K++++ +K KK E +
Sbjct: 636 VRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKI 695
Query: 143 SYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDM-------- 194
Y+ R + + A+ +Q D ++ + +EE + Q++
Sbjct: 696 DYF-------ERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKN 748
Query: 195 RAAQVAQDEE--IARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANS----K 248
R +++ +D + + RL A + +K K+ E+ ++R E + + K +
Sbjct: 749 RMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYR 808
Query: 249 SKESDEPHHSKNE 261
KE +E ++ +
Sbjct: 809 EKEEEEQRRAEEQ 821
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 49.3 bits (116), Expect = 4e-06
Identities = 48/242 (19%), Positives = 113/242 (46%), Gaps = 28/242 (11%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDC----EIAQ 89
+++E E +R R + + + ++ + E + + + +KR ++ +++D ++ +
Sbjct: 389 RDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLER 448
Query: 90 EIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDG 149
+++EK A ER + E ++ R +++ +EE++R++ E + + + Y+D
Sbjct: 449 KLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLED--YDDD 506
Query: 150 GMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLL 209
P+ + + + R+ R++E E RK ++EEL EEI + L
Sbjct: 507 RDDPKYYRGS-ALQKRLRDREKEMEADERDRKREKEEL---------------EEIRQRL 550
Query: 210 MAE-----EKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPA 264
+AE + + + +E E+ + KQ+PE + + K ++ +EP + E
Sbjct: 551 LAEGHPDPDAELQRMEQEAERRRQPQIKQEPE-SEEEEEEKQEKEEKREEPMEEEEEPEQ 609
Query: 265 RP 266
+P
Sbjct: 610 KP 611
Score = 36.6 bits (83), Expect = 0.029
Identities = 43/196 (21%), Positives = 84/196 (42%), Gaps = 27/196 (13%)
Query: 71 AQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKH 130
++ + +K LE++ + +E QE IE ERR + +++ + R +E+E + E++R+K
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQE---IEKERRERERERERERERREREREREREREREKE 338
Query: 131 FPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLAT 190
+ +E R RD++ D E R E
Sbjct: 339 --------------------KERERERERDRDRDRTKERDRD-RDRERDRDRDRERSSDR 377
Query: 191 QVD-MRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKS 249
D R+ + ++D E R E ++ ++ +ERE+ +R+++ E + + K + +
Sbjct: 378 NKDRSRSREKSRDRERER--EREREREREREREREREREREREREREREREKDKKRDREE 435
Query: 250 KESDEPHHSKNERPAR 265
E D K ER R
Sbjct: 436 DEEDAYERRKLERKLR 451
Score = 33.5 bits (75), Expect = 0.24
Identities = 46/217 (21%), Positives = 89/217 (41%), Gaps = 32/217 (14%)
Query: 60 KQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEK 119
K+L+EE K + + Q+ K+ +++ E +E + + E ER R +E++ E +EK
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERR---ERERERERERERE------KEK 339
Query: 120 ELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQE------- 172
E + E++R + D D + + + SR RD+E
Sbjct: 340 ERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERER 399
Query: 173 --------WYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKERE 224
+ E R+ + E + D + + +DEE A E +K +K +E+E
Sbjct: 400 EREREREREREREREREREREREREREKDKKRDR-EEDEEDA----YERRKLERKLREKE 454
Query: 225 KSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNE 261
+ ++ K W+ + K KE++ + E
Sbjct: 455 AAYQERLK---NWEIRERKKTREYEKEAEREEERRRE 488
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/188 (23%), Positives = 89/188 (47%), Gaps = 13/188 (6%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
+ Q+R K+L +QQ+ E + +E++ E ERRR + +++ + K+L+E+++
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQE------YKRKQLEEQRQA 457
Query: 128 KKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEI----ARKLQ 183
++ + R Y S ++ +P K M+ ++ + EI A K Q
Sbjct: 458 ERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQ 517
Query: 184 EEELLATQ 191
L A+Q
Sbjct: 518 GPALTASQ 525
Score = 34.3 bits (77), Expect = 0.14
Identities = 32/151 (21%), Positives = 63/151 (41%), Gaps = 18/151 (11%)
Query: 117 QEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQE---- 172
Q E Q + K H R D YE G + + PS + + E
Sbjct: 292 QPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLR 351
Query: 173 --WYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDK 230
+ ++A K + E L Q++ Q ++EE R L+AE +K ++ KE+ + ++
Sbjct: 352 RDFLRLQLANKERSEALRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQ 408
Query: 231 RKQDPEWKPKTAKAANSKSKESDEPHHSKNE 261
++++ E + K +E ++ H + +
Sbjct: 409 QRREKELR---------KQQEREQRRHYEEQ 430
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/188 (23%), Positives = 89/188 (47%), Gaps = 13/188 (6%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
+ Q+R K+L +QQ+ E + +E++ E ERRR + +++ + K+L+E+++
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQE------YKRKQLEEQRQA 457
Query: 128 KKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEI----ARKLQ 183
++ + R Y S ++ +P K M+ ++ + EI A K Q
Sbjct: 458 ERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQ 517
Query: 184 EEELLATQ 191
L A+Q
Sbjct: 518 GPALTASQ 525
Score = 34.3 bits (77), Expect = 0.14
Identities = 32/151 (21%), Positives = 63/151 (41%), Gaps = 18/151 (11%)
Query: 117 QEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQE---- 172
Q E Q + K H R D YE G + + PS + + E
Sbjct: 292 QPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLR 351
Query: 173 --WYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDK 230
+ ++A K + E L Q++ Q ++EE R L+AE +K ++ KE+ + ++
Sbjct: 352 RDFLRLQLANKERSEALRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQ 408
Query: 231 RKQDPEWKPKTAKAANSKSKESDEPHHSKNE 261
++++ E + K +E ++ H + +
Sbjct: 409 QRREKELR---------KQQEREQRRHYEEQ 430
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 49.3 bits (116), Expect = 4e-06
Identities = 69/265 (26%), Positives = 117/265 (44%), Gaps = 61/265 (23%)
Query: 34 QEQEIEHHLASNV---------QRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQD 84
Q+Q IE A N+ ++ + H++ K+++ E+L+ Q + +K
Sbjct: 412 QKQSIEPDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKK--------- 462
Query: 85 CEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSY 144
A + +E LA + ++EK+ + IA K+ EEK +KK E A + A
Sbjct: 463 ---AAKREEALASFEAWKAMKEKEAKKIAA----KKRLEEKNKKKTEEENAARKGEALQA 515
Query: 145 YYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEE 204
+ + K +KE ++++ + E A+K +EEE +A + +D
Sbjct: 516 FEKWKEKKMEYLKE----------KNRKEREYERAKKQKEEETVAEK--------KKDNL 557
Query: 205 IARLLMAEEKKAYKKAKEREKSSLDKRKQD---PEWKPKTAKAANS-----KSKESDE-- 254
A E+K+A+ K KE+EK + +KRK++ E K K +A N ++KE E
Sbjct: 558 TAVEKWNEKKEAFFKQKEKEKIN-EKRKEELKRAEKKDKDKQAINEYEKWLENKEKQERI 616
Query: 255 -----PHHSKNERPARPP--PPIMT 272
HS E A PP PP T
Sbjct: 617 ERKQKKRHSFLESEALPPWSPPSRT 641
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 48.9 bits (115), Expect = 6e-06
Identities = 55/265 (20%), Positives = 117/265 (44%), Gaps = 25/265 (9%)
Query: 1 MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAK 60
MAE Q +L E+C + L A + +EI H L + V+ + +
Sbjct: 879 MAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEE------ERCQ 932
Query: 61 QLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKK---DEDIARLLQ 117
LQ E K Q +Q+ + LE+++ + EK+ EA+ ++++E++ ++ +L +
Sbjct: 933 HLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAK 992
Query: 118 EKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAE 177
EK+L E++ EF + +K + R+ +++ + E
Sbjct: 993 EKKLLEDR-----IAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE 1047
Query: 178 IARKLQEEEL--LATQVDMRAAQVAQ--------DEEI-ARLLMAEEKKAYKKAKEREKS 226
R+ E + L+ Q+ AQ+A+ +EE+ A L EE+ A K ++
Sbjct: 1048 KTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIR 1107
Query: 227 SLDKRKQDPEWKPKTAKAANSKSKE 251
L+ + + + ++ +A+ +K+++
Sbjct: 1108 ELESQISELQEDLESERASRNKAEK 1132
Score = 36.2 bits (82), Expect = 0.037
Identities = 59/272 (21%), Positives = 112/272 (41%), Gaps = 38/272 (13%)
Query: 14 VKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQ-AQ 72
V E+ + LE Q +E+E L + ++ +LQ K E DL+ + Q
Sbjct: 1520 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ 1579
Query: 73 LQKRYKDLEQQDCEIAQEI-----QEKLAIEAERRRIQEKKD----EDIARLLQEKELQE 123
+++ K L +Q E+ E+ Q +A+ A ++ + KD D A +++ +++
Sbjct: 1580 SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQ 1639
Query: 124 EKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQ 183
+K + + R D+ R +E + ++ + + +AE+ +
Sbjct: 1640 LRKLQAQMKD--CMRELDDT----------RASREEILAQAKENEKKLKSMEAEMIQ--L 1685
Query: 184 EEELLATQVDMRAAQVAQDE---EIAR-----LLMAEEKKAYKKAKEREKSSLDKRKQDP 235
+EEL A + R AQ +DE EIA L EEK+ + + + L++ + +
Sbjct: 1686 QEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNT 1745
Query: 236 EWKPKTAKAAN------SKSKESDEPHHSKNE 261
E K AN + + H KNE
Sbjct: 1746 ELINDRLKKANLQIDQINTDLNLERSHAQKNE 1777
Score = 35.4 bits (80), Expect = 0.064
Identities = 52/243 (21%), Positives = 103/243 (42%), Gaps = 14/243 (5%)
Query: 25 EDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQD 84
E + L +L+E+ H R + Q ++A+QL E+ + +A L+K + LE +
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQL-EQTKRVKANLEKAKQTLENER 1226
Query: 85 CEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSY 144
E+A E++ L + + + KK E + LQ K + E+ R + + + D+
Sbjct: 1227 GELANEVKVLLQGKGDSEH-KRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNV 1285
Query: 145 YYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEE 204
G + K + T A Q E+ LQEE + + QV ++
Sbjct: 1286 ---TGLLSQSDSKSSKLTKDFSALESQLQDTQEL---LQEENRQKLSLSTKLKQVEDEKN 1339
Query: 205 IARLLMAEEKKAYKKAKER------EKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHS 258
R + EE++A +++ + + + K+ +D +TA+ K ++ E
Sbjct: 1340 SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 1399
Query: 259 KNE 261
++E
Sbjct: 1400 RHE 1402
Score = 34.7 bits (78), Expect = 0.11
Identities = 63/297 (21%), Positives = 114/297 (38%), Gaps = 34/297 (11%)
Query: 15 KEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQ 74
K++ D LE H + + E L + + +L + +EE L + +
Sbjct: 1613 KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENE 1672
Query: 75 KRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDE---DIARLLQEKELQEEKKRKKHF 131
K+ K +E E+ Q +E A E +R+ Q+++DE +IA + L E+KR+
Sbjct: 1673 KKLKSME---AEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1729
Query: 132 P----EFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRM----------AHRDQEWYDAE 177
E ++ D K + + ++T + A + E + E
Sbjct: 1730 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKE 1789
Query: 178 IARKLQEEE-----LLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSL---- 228
+ KLQE E + A++AQ EE E + A K+ + EK
Sbjct: 1790 LKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLL 1849
Query: 229 ---DKRKQDPEWKPKTAKAAN--SKSKESDEPHHSKNERPARPPPPIMTDGEDADYT 280
D+R+ ++K + KA+ + K E + +R + + EDA T
Sbjct: 1850 QVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATET 1906
Score = 34.3 bits (77), Expect = 0.14
Identities = 61/257 (23%), Positives = 110/257 (42%), Gaps = 50/257 (19%)
Query: 16 EVCRDFAVLEDHTL-AHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEED-------- 66
++ +DF+ LE L ++E L+ + + ++ +QL+EE+
Sbjct: 1298 KLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK 1357
Query: 67 ----LKAQ-AQLQKRYKD----LE---------QQDCE-IAQEIQEKLA----IEAERRR 103
L AQ A ++K+ +D LE Q+D E ++Q +EK+A +E + R
Sbjct: 1358 QIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTR 1417
Query: 104 IQEKKDEDIARLLQEKE--LQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVS 161
+Q++ D+ + L +++ EKK+KK F + A + Y E+ + R EA
Sbjct: 1418 LQQELDDLLVDLDHQRQSACNLEKKQKK-FDQLLAEEKTISAKYAEE---RDRAEAEA-- 1471
Query: 162 TPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAK 221
R++E +AR L+E +++ Q + E LM+ + K
Sbjct: 1472 -------REKETKALSLARALEEAMEQKAELERLNKQFRTEMED---LMSSKDDVGKSVH 1521
Query: 222 EREKSSLDKRKQDPEWK 238
E EKS +Q E K
Sbjct: 1522 ELEKSKRALEQQVEEMK 1538
Score = 34.3 bits (77), Expect = 0.14
Identities = 41/202 (20%), Positives = 84/202 (41%), Gaps = 24/202 (11%)
Query: 50 RLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKD 109
R +Q DL+ Q EE + A +L+K L+Q+ ++ ++ + + Q+K D
Sbjct: 1388 RKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFD 1447
Query: 110 EDI-------ARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVST 162
+ + A+ +E++ E + R+K RA ++ M+ + E ++
Sbjct: 1448 QLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEA-------MEQKAELERLNK 1500
Query: 163 PSRMAHRDQEWYDAEIARKLQEEE----LLATQVDMRAAQVAQDE------EIARLLMAE 212
R D ++ + + E E L QV+ Q+ + E E A+L +
Sbjct: 1501 QFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV 1560
Query: 213 EKKAYKKAKEREKSSLDKRKQD 234
+A K ER+ D++ ++
Sbjct: 1561 NLQAMKAQFERDLQGRDEQSEE 1582
Score = 33.9 bits (76), Expect = 0.19
Identities = 46/212 (21%), Positives = 77/212 (36%), Gaps = 41/212 (19%)
Query: 24 LEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQ 83
LE + S Q E++ +A + + +LQ A EE+ + K+ ++LE Q
Sbjct: 1053 LEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQ 1112
Query: 84 DCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADS 143
E+QE L E R EK+ D+ L+
Sbjct: 1113 ----ISELQEDLESERASRNKAEKQKRDLGEELE-------------------------- 1142
Query: 144 YYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQV---DMRAAQVA 200
+K + ST ++ R + + I +K EEE + +MR
Sbjct: 1143 ------ALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQ 1196
Query: 201 QDEEIARLLMAEEKKAYKKAKEREKSSLDKRK 232
EE+A L E+ K K E+ K +L+ +
Sbjct: 1197 AVEELAEQL--EQTKRVKANLEKAKQTLENER 1226
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 48.9 bits (115), Expect = 6e-06
Identities = 56/270 (20%), Positives = 115/270 (42%), Gaps = 35/270 (12%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQE 93
Q QE E + ++ R + + ++ E K + +++ +D E++ E + ++E
Sbjct: 349 QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLRE 408
Query: 94 KLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR----KKHFPEFPATRAYADSYYYEDG 149
K ER R QEK E + ++ +EK++QE++K+ ++ E R E+
Sbjct: 409 K----EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464
Query: 150 GMKPRVMKEAVSTPSRMAHRDQEWYD---AEIARKLQEEELLATQVDMRAAQVAQDEEIA 206
M+ + K + ++EW E KL E+E + Q + ++ + EE
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE----KIWEQEEKI 520
Query: 207 R---LLMAEEKKAYKKAKEREKS----SLDKRKQDPEWK-------------PKTAKAAN 246
R + +EKK +++ K RE+ +++ +D E K + K +
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580
Query: 247 SKSKESDEPHHSKNERPARPPPPIMTDGED 276
+ K +E + E+ R +M + E+
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEE 610
Score = 48.9 bits (115), Expect = 6e-06
Identities = 52/268 (19%), Positives = 127/268 (47%), Gaps = 23/268 (8%)
Query: 8 QSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDL--QVAKQLQEE 65
Q +LP KE + +++ QE++I Q ++ + + + Q+ E+
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549
Query: 66 DLKAQAQLQKRYKDLEQQDCEIAQEI-----QEKLAIEAERRRIQEKKDEDIARLLQEKE 120
+ K + Q QK + E+ + + ++ QE+ E ER R +EKK + +++E+E
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609
Query: 121 --LQEEKKR-----KKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEW 173
+QE++++ +K + + + + + ++ M + +E + R+ + ++
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ--EEKMWEQQRLPEQKEKL 667
Query: 174 YDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQ 233
++ E K+QE+E + Q + ++ + E++ + +EKK + + K RE+ S+ +R++
Sbjct: 668 WEHE---KMQEQEKMQEQEE----KIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK 720
Query: 234 DPEWKPKTAKAANSKSKESDEPHHSKNE 261
+ + + K +E +E + E
Sbjct: 721 KMREEEEMMREQEEKMQEQEEKMQEQEE 748
Score = 46.2 bits (108), Expect = 4e-05
Identities = 42/192 (21%), Positives = 90/192 (46%), Gaps = 19/192 (9%)
Query: 63 QEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQ 122
QE++L+ Q + + K+L +Q+ E QE +EK+ + E+ R QE+K QE+ L
Sbjct: 326 QEKELREQEKELREQKELREQE-EQMQEQEEKMWEQEEKMREQEEK-----MWRQEERLW 379
Query: 123 EEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKL 182
E++K+ + + R + + +D ++ + RM +++ W E K+
Sbjct: 380 EQEKQMRE--QEQKMRDQEERMWEQDERLREK--------EERMREQEKMWEQVE---KM 426
Query: 183 QEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTA 242
+EE+ + Q Q + +E R+ E+K ++ RE+ +++++ W+ +
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Query: 243 KAANSKSKESDE 254
+ + E E
Sbjct: 487 EWQQQRLPEQKE 498
Score = 44.3 bits (103), Expect = 1e-04
Identities = 51/237 (21%), Positives = 105/237 (44%), Gaps = 15/237 (6%)
Query: 34 QEQEIEHHLASNVQRNRLVQHD--LQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEI 91
++Q E Q R+ + D L+ ++ E K Q++K ++ + Q+ E
Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD 441
Query: 92 QEKLAIEAERRRIQEKK---DEDIARLLQEK-ELQEEKKRKKHFPEFPATR--AYADSYY 145
QE+ E ER R +EKK +E+ R +EK + QEE ++ E+ R + +
Sbjct: 442 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 501
Query: 146 YEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEI 205
++ K + +E + +E + E +K+ +E + Q D Q + +
Sbjct: 502 EQE---KMQEQEEKIWEQEEKIRDQEEMWGQE--KKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 206 ARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNER 262
+ + +E++ KK +E+EK + D+ ++ E + + K +E +E + E+
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMRE--EERMREREKKMREEEEMMREQEEK 611
Score = 43.5 bits (101), Expect = 2e-04
Identities = 43/209 (20%), Positives = 97/209 (46%), Gaps = 8/209 (3%)
Query: 56 LQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARL 115
LQ QEE+L+ Q + ++ ++ + E +E + K+ + E+ QEK+ + +
Sbjct: 270 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKE 329
Query: 116 L--QEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEW 173
L QEKEL+E+K+ ++ + + + + ++ M+ + K R+ ++++
Sbjct: 330 LREQEKELREQKELREQEEQM---QEQEEKMWEQEEKMREQEEK-MWRQEERLWEQEKQM 385
Query: 174 YDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQ 233
+ E + QEE + +R + E+ E+ + KK +E+EK + D+ ++
Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445
Query: 234 DPEWKPKTAKAANSKSKESDEPHHSKNER 262
E + + K +E +E + E+
Sbjct: 446 MQE--EERIREREKKMREEEETMREQEEK 472
Score = 43.1 bits (100), Expect = 3e-04
Identities = 37/177 (20%), Positives = 85/177 (48%), Gaps = 14/177 (7%)
Query: 60 KQLQEEDLKAQAQLQKRYKDLE--QQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQ 117
+++QE++ K Q Q +K ++ E Q+ E E +EK+ + E+ Q++ E +L +
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 669
Query: 118 EKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAE 177
+++QE++K ++ + +E M+ + ++ T + R++E
Sbjct: 670 HEKMQEQEKMQEQ-----------EEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 178 IARKLQEEELLATQVD-MRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQ 233
+ +EEE++ Q + M+ + E+ + EEK ++ K E+ L ++K+
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKE 775
Score = 40.8 bits (94), Expect = 0.002
Identities = 44/222 (19%), Positives = 99/222 (44%), Gaps = 11/222 (4%)
Query: 63 QEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQ 122
QEE ++ Q ++ + K + +Q E +E ++++ + E+ R QE+K D +++K +
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQ--EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQE 573
Query: 123 EEKK---RKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIA 179
+EKK +++ E R E+ M+ + K ++ W E
Sbjct: 574 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM 633
Query: 180 RKLQE-----EELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQD 234
++ +E EE + Q + Q E+ +L E+ + +K +E+E+ ++ K +
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 235 PEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGED 276
+ + + K + + K +E + E+ R +M + E+
Sbjct: 694 KKTQEQEKKTWD-QEKMREEESMREREKKMREEEEMMREQEE 734
Score = 40.8 bits (94), Expect = 0.002
Identities = 46/250 (18%), Positives = 115/250 (46%), Gaps = 30/250 (12%)
Query: 34 QEQEIEHHLASNVQRNRLVQHD-LQVAKQLQEED----------LKAQAQLQKRYKDLEQ 82
QE+++ Q+ +L +H+ +Q +++QE++ K Q Q +K + +
Sbjct: 650 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKM 709
Query: 83 QDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYAD 142
++ E +E ++K+ E E R QE+K ++ +QE+E + ++ +K + + +
Sbjct: 710 REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQ--------E 761
Query: 143 SYYYEDGGMKPRVMK----EAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQ 198
+E + + K E + ++ ++++ D E + QEE++ + MR +
Sbjct: 762 EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 199 V---AQDEEI---ARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKES 252
Q+E++ + +E+K + + ++ E+ + ++ E + K + K +E
Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEK-MRGQEEKMREQ 880
Query: 253 DEPHHSKNER 262
+E + E+
Sbjct: 881 EEKMRGQEEK 890
Score = 39.3 bits (90), Expect = 0.004
Identities = 49/237 (20%), Positives = 108/237 (45%), Gaps = 17/237 (7%)
Query: 39 EHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRY----KDLEQQDCEIAQEI--- 91
E L + R + +L+ K+L+E++ + Q Q +K + K EQ++ QE
Sbjct: 320 EKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW 379
Query: 92 -QEKLAIEAERR-RIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDG 149
QEK E E++ R QE++ + L+EKE + ++++K + + R + ++
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQVEKMR---EEKKMQEQ 435
Query: 150 GMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLL 209
K R +E + R+ R+++ + E + QEE++ + +M + + ++
Sbjct: 436 EKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 495
Query: 210 MAEEKKAYKKAKEREKSSLDK----RKQDPEWKPKTAKAANSKSKESDEPHHSKNER 262
E+ +K +E+E+ ++ R Q+ W + K +E ++ + E+
Sbjct: 496 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Score = 31.2 bits (69), Expect = 1.2
Identities = 38/189 (20%), Positives = 81/189 (42%), Gaps = 22/189 (11%)
Query: 90 EIQEKLAI-EAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYED 148
E+QEKL + E+E+ IQ L KEL+ + +R K T + + ++
Sbjct: 229 ELQEKLPLAESEKSEIQ----------LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 278
Query: 149 GGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARL 208
++ + K+ +M +++ + E + QEE++ + +R Q++E+
Sbjct: 279 EELREQE-KKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLRE----QEKELR-- 331
Query: 209 LMAEEKKAYKKAKE-REKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPP 267
E++K ++ KE RE+ + +++ W+ + + E + E+ R
Sbjct: 332 ---EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 388
Query: 268 PPIMTDGED 276
M D E+
Sbjct: 389 EQKMRDQEE 397
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 48.9 bits (115), Expect = 6e-06
Identities = 53/238 (22%), Positives = 110/238 (46%), Gaps = 22/238 (9%)
Query: 30 AHSLQEQEIEHHLASNVQRNRLVQHD-----LQVAKQLQEEDLKAQAQLQKRYKDLEQQ- 83
A L+ Q++E ++ +L + + LQ +++++ + + Q+++++ ++++
Sbjct: 551 AEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKT 610
Query: 84 ----DCEIAQEIQEKLAI-----EAERRRIQEKKDEDIARLLQEKE---LQEEKKRKKHF 131
+ +A+E +K A E E RR QE++ + L QE+E QE ++KK
Sbjct: 611 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 670
Query: 132 PEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQ 191
+ +A E + R + R+QE + E R+L E+E Q
Sbjct: 671 EQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE--RQLAEQERRREQ 728
Query: 192 VDMRAAQVAQDEEIARLLMAE--EKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANS 247
++A + Q+ E A L E +++ +K K+ E+ L +R+ E + K +AA +
Sbjct: 729 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGA 786
Score = 48.5 bits (114), Expect = 7e-06
Identities = 48/234 (20%), Positives = 106/234 (45%), Gaps = 22/234 (9%)
Query: 46 VQRNRLVQHDLQVAKQLQEEDLKAQAQLQ------------KRYKDLEQQDCEIAQEIQE 93
VQRN+++ + + + +K L+ +R ++L ++ E A++++
Sbjct: 499 VQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRK--EEAEQLRR 556
Query: 94 KLAIEAERRRIQE---KKDEDIARLLQEKELQE---EKKRKKHFPEFPATRAYADSYYYE 147
+ E +RRR++E K++E + ++LQ +E E E+K+K+ +F + E
Sbjct: 557 QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEE 616
Query: 148 DGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIAR 207
+ K A + R ++ +A R LQ+EE ++ Q ++EE R
Sbjct: 617 RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL--LQKKKEEEQER 674
Query: 208 LLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNE 261
L A E K + +E+E+ ++R+Q+ + + + + ++ E + +
Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 728
Score = 44.3 bits (103), Expect = 1e-04
Identities = 47/229 (20%), Positives = 106/229 (46%), Gaps = 27/229 (11%)
Query: 2 AEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQV--A 59
A ++Q K K++ + FA +++ T E+ E LA + + ++ A
Sbjct: 584 ARERVEQMKEEKKKQIEQKFAQIDEKT------EKAKEERLAEEKAKKKAAAKKMEEVEA 637
Query: 60 KQLQEEDLKAQAQLQKRYKDLEQQDC--EIAQEIQEKLAIEAERRRIQEKKDEDIARLLQ 117
++ QEE+ + LQ+ ++ Q+ + +E QE+L AE +R+ E+++++ +
Sbjct: 638 RRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQE----RR 693
Query: 118 EKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAE 177
E+E +E+++R++ E E + ++ ++ ++E + E
Sbjct: 694 EQERREQERREQERRE------------QERREQERQLAEQERRREQERLQAERELQERE 741
Query: 178 IARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKS 226
A +LQ+E+ L +++ + + Q R L E++K K+A K+
Sbjct: 742 KALRLQKEQ-LQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKA 789
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 48.5 bits (114), Expect = 7e-06
Identities = 67/282 (23%), Positives = 121/282 (42%), Gaps = 21/282 (7%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
+ Q+R K+L +QQ+ E + +E++ E ERRR E + E I R L+E++ Q E +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRR-AEHEQEYIRRQLEEEQRQLEILQ 462
Query: 128 KKHFPEFPATRAYADSYYYEDGGMK--PRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEE 185
++ E Y E + R +K+ + H+ QE R ++++
Sbjct: 463 QQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQE------QRPVEKK 516
Query: 186 ELLATQVDMRAAQ-VAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKA 244
L + M ++ A +EI L+ A K +S +Q + +A
Sbjct: 517 PLYHYKEGMSPSEKPAWAKEIPHLV------AVKSQGPALTASQSVHEQPTKGLSGFQEA 570
Query: 245 ANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQ 286
N S + P +N P PP+ T E D + + Q+
Sbjct: 571 LNVTSHRVEMPR--QNSDPTSENPPLPTRIEKFDRSSWLRQE 610
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 48.5 bits (114), Expect = 7e-06
Identities = 67/282 (23%), Positives = 121/282 (42%), Gaps = 21/282 (7%)
Query: 11 LPGVKEVCRDFAVLE--DHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLK 68
LPG + RDF L+ + + +L+ Q++E N + R + + Q + Q+E +
Sbjct: 344 LPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRR 403
Query: 69 AQAQLQKRYKDL-EQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKR 127
+ Q+R K+L +QQ+ E + +E++ E ERRR E + E I R L+E++ Q E +
Sbjct: 404 RLEEQQRREKELRKQQEREQRRHYEEQMRREEERRR-AEHEQEYIRRQLEEEQRQLEILQ 462
Query: 128 KKHFPEFPATRAYADSYYYEDGGMK--PRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEE 185
++ E Y E + R +K+ + H+ QE R ++++
Sbjct: 463 QQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQE------QRPVEKK 516
Query: 186 ELLATQVDMRAAQ-VAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKA 244
L + M ++ A +EI L+ A K +S +Q + +A
Sbjct: 517 PLYHYKEGMSPSEKPAWAKEIPHLV------AVKSQGPALTASQSVHEQPTKGLSGFQEA 570
Query: 245 ANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQ 286
N S + P +N P PP+ T E D + + Q+
Sbjct: 571 LNVTSHRVEMPR--QNSDPTSENPPLPTRIEKFDRSSWLRQE 610
>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
sapiens]
Length = 1719
Score = 48.1 bits (113), Expect = 9e-06
Identities = 52/235 (22%), Positives = 95/235 (40%), Gaps = 33/235 (14%)
Query: 55 DLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEK------LAIEAERRRIQEKK 108
DL V Q ++ A ++R K LEQ+ E+++++QE L + K
Sbjct: 426 DLDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGPLTASK 485
Query: 109 DEDIARLLQE-----KELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVM------- 156
D +I L +E K++ E ++ E A R D + + + ++
Sbjct: 486 DLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQERE 545
Query: 157 ---KEAVSTPSRMAHRDQEWYDAEIARKLQEEEL---------LATQVDMRAAQVAQDEE 204
KE V R+ ++ +E DA RKL +E L TQ A V EE
Sbjct: 546 DLNKELVQASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEE 605
Query: 205 IARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSK 259
L+M + + ++ + E++ K++ + + A+A+ + H+SK
Sbjct: 606 EVDLVMQKVESLRQELRRTERA---KKELEVHTEALAAEASKDRKLREQSEHYSK 657
Score = 28.5 bits (62), Expect = 7.8
Identities = 50/237 (21%), Positives = 95/237 (40%), Gaps = 22/237 (9%)
Query: 24 LEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEE------DLKAQAQLQKRY 77
LE HT A + + + + ++ ++++L+ KQ Q ++ Q ++ K
Sbjct: 631 LEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLK 690
Query: 78 KDLEQQDCEIAQEIQEKLAIEAERRRIQEKK--DEDIARLLQEKELQ--EEKKRKKHFPE 133
DLE++ +E+ ++ I A + +K+ D + +L KE+ ++K K
Sbjct: 691 TDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRES 750
Query: 134 FPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEEL--LATQ 191
+ + + K + +E S + + + I + EEE+ LA +
Sbjct: 751 QSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEVKDLADK 810
Query: 192 VDMRAAQVAQ---------DEEIAR-LLMAEEKKAYKKAKEREKSSLDKRKQDPEWK 238
+ A AQ DE+ AR L A K ++ + SSL R D WK
Sbjct: 811 KESVAHWEAQITEIIQWVSDEKDARGYLQALASKMTEELEALRNSSLGTRATDMPWK 867
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 47.8 bits (112), Expect = 1e-05
Identities = 56/241 (23%), Positives = 107/241 (44%), Gaps = 15/241 (6%)
Query: 27 HTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCE 86
H A +I + + N NR+ + Q ++ +L + +QK ++ ++ +
Sbjct: 27 HVQALKNVNSQIRNQMVQNENDNRVQRKQFLRLLQNEQFELDMEEAIQKAEENKRLKELQ 86
Query: 87 IAQEIQEKLAIEAERRRIQEKKDEDIARLLQEK--ELQE-EKKRKKHF--PEFPATRAYA 141
+ QE EKLA+E + + + KDE + + ++E EL+E EKK K + E A A
Sbjct: 87 LKQE--EKLAMELAKLKHESLKDEKMRQQVRENSIELRELEKKLKAAYMNKERAAQIAEK 144
Query: 142 DSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVD--MRAAQV 199
D+ YE + K + R+ + D K Q L Q++ + Q
Sbjct: 145 DAIKYEQMKRDAEIAKTMMEEHKRIIKEENAAEDKRNKAKAQYYLDLEKQLEEQEKKKQE 204
Query: 200 AQDEEIARLLMAEE--KKAYKKAKEREKSSLDK----RKQDPEWKPKTAKAANSKSKESD 253
A ++ + LM +E +K Y++ + ++ L+K R+ E++ + A K +E +
Sbjct: 205 AYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEME 264
Query: 254 E 254
E
Sbjct: 265 E 265
Score = 46.2 bits (108), Expect = 4e-05
Identities = 48/202 (23%), Positives = 94/202 (46%), Gaps = 22/202 (10%)
Query: 44 SNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRR 103
+ + + + +H + ++ ED + +A+ Q Y DLE+Q E QEK EA +
Sbjct: 156 AEIAKTMMEEHKRIIKEENAAEDKRNKAKAQY-YLDLEKQ-----LEEQEKKKQEAYEQL 209
Query: 104 IQEKK--DEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDG---GMKPRVMKE 158
++EK DE + ++ +E +L++++K +K A R Y + + E K M+E
Sbjct: 210 LKEKLMIDEIVRKIYEEDQLEKQQKLEK----MNAMRRYIEEFQKEQALWRKKKREEMEE 265
Query: 159 AVSTPSRMAHRDQEWYDAEIAR-------KLQEEELLATQVDMRAAQVAQDEEIARLLMA 211
A+ Q+ + +A+ +LQ + L +++ Q E++ + L
Sbjct: 266 ENRKIIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQELYQ 325
Query: 212 EEKKAYKKAKEREKSSLDKRKQ 233
EE+ K+K +E++ RKQ
Sbjct: 326 EEQAEIYKSKLKEEAEKKLRKQ 347
Score = 38.1 bits (87), Expect = 0.010
Identities = 43/208 (20%), Positives = 84/208 (40%), Gaps = 15/208 (7%)
Query: 46 VQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQ 105
V N + +Q K + + Q + + +Q + Q Q +L +E ++ +
Sbjct: 18 VDENYCKKLHVQALKNVNSQIRNQMVQNENDNRVQRKQFLRLLQNEQFELDMEEAIQKAE 77
Query: 106 EKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSR 165
E K +L QE++L E + KH +D M+ +V + ++
Sbjct: 78 ENKRLKELQLKQEEKLAMELAKLKH-------------ESLKDEKMRQQVRENSIELREL 124
Query: 166 MAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQD--EEIARLLMAEEKKAYKKAKER 223
+ + E A ++ E++ + + R A++A+ EE R++ E K+ K +
Sbjct: 125 EKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKEENAAEDKRNKAK 184
Query: 224 EKSSLDKRKQDPEWKPKTAKAANSKSKE 251
+ LD KQ E + K +A KE
Sbjct: 185 AQYYLDLEKQLEEQEKKKQEAYEQLLKE 212
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 47.4 bits (111), Expect = 2e-05
Identities = 51/226 (22%), Positives = 110/226 (48%), Gaps = 26/226 (11%)
Query: 55 DLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEI--QEKLAIEAE--RRRIQEKK-- 108
+LQ ++LQ++ + +LQ R LE++ +A+++ + +L EAE R R+ +K
Sbjct: 885 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 944
Query: 109 -----DEDIARLLQEKE----LQEEKKR-KKHFPEFPATRAYADSYYYEDGGMKPRVMKE 158
E AR+ +E+E +Q EKKR ++H E +++ + G + ++ E
Sbjct: 945 LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQEL-------EAHLEAEEGARQKLQLE 997
Query: 159 AVSTPSRMAHRDQE--WYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKA 216
V+T ++M +++ + + ++ +E +LL ++ ++Q A++EE + L K
Sbjct: 998 KVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLK- 1056
Query: 217 YKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNER 262
Y+ + L K ++ + K + + +S E E + +R
Sbjct: 1057 YEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQR 1102
Score = 35.8 bits (81), Expect = 0.049
Identities = 47/212 (22%), Positives = 93/212 (43%), Gaps = 26/212 (12%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQV--------AKQLQEEDLKAQAQLQKRYKDLEQQDC 85
+ +E LA+ Q LV +L+ ++Q+Q E + Q +Q+ LE ++
Sbjct: 930 EAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEG 989
Query: 86 EIAQEIQEKLAIEAERRRIQEK---KDEDIARLLQEKELQEEKKRKKHFPEFPATRAYAD 142
+ EK+ EA+ ++ +E ++ ++L +E++L E++ EF + A +
Sbjct: 990 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDR-----LAEFSSQAAEEE 1044
Query: 143 SYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQD 202
K R+ EA R +E + QE E L ++D ++++ Q+
Sbjct: 1045 EKVKSLN--KLRLKYEATIADMEDRLRKEE-------KGRQELEKLKRRLDGESSEL-QE 1094
Query: 203 EEIARLLMAEEKKAYKKAKEREKSSLDKRKQD 234
+ + + AEE +A KE E + R +D
Sbjct: 1095 QMVEQQQRAEELRAQLGRKEEELQAALARAED 1126
Score = 34.7 bits (78), Expect = 0.11
Identities = 44/212 (20%), Positives = 93/212 (43%), Gaps = 17/212 (8%)
Query: 50 RLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQ----QDCEIAQEIQEKLAIEAERRRIQ 105
R +Q +L A E+ + + L+K+ + +Q + + + ++E+ EAE R +
Sbjct: 1448 RRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 1507
Query: 106 EKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYY--YEDGGMKPRVMKEAVSTP 163
+ L +E+E +EE +R+ A RA ++ +D G ++ A
Sbjct: 1508 ARALSLTRALEEEQEAREELERQNR-----ALRAELEALLSSKDDVGKSVHELERACRVA 1562
Query: 164 SRMAHRDQEWYDAEIARKL--QEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAK 221
+ A+ D E+ +L E+ L +V ++A + + ++ A E++ + AK
Sbjct: 1563 EQAAN-DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAK 1621
Query: 222 EREKSSLDKRKQDPEWKPKTAKAANSKSKESD 253
+ + +++ D E K +T A K E +
Sbjct: 1622 QLRDAEVER---DEERKQRTLAVAARKKLEGE 1650
Score = 30.0 bits (66), Expect = 2.7
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 33 LQEQEIEHHLASNVQRNRL--VQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQE 90
LQEQ +E + R +L + +LQ A E++ A+AQL K ++ + E
Sbjct: 1092 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQ----AALAE 1147
Query: 91 IQEKLAIEAERRRIQEKKDEDIARLLQ 117
QE L E R EK+ D+ L+
Sbjct: 1148 AQEDLESERVARTKAEKQRRDLGEELE 1174
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 47.4 bits (111), Expect = 2e-05
Identities = 51/226 (22%), Positives = 110/226 (48%), Gaps = 26/226 (11%)
Query: 55 DLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEI--QEKLAIEAE--RRRIQEKK-- 108
+LQ ++LQ++ + +LQ R LE++ +A+++ + +L EAE R R+ +K
Sbjct: 877 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 936
Query: 109 -----DEDIARLLQEKE----LQEEKKR-KKHFPEFPATRAYADSYYYEDGGMKPRVMKE 158
E AR+ +E+E +Q EKKR ++H E +++ + G + ++ E
Sbjct: 937 LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQEL-------EAHLEAEEGARQKLQLE 989
Query: 159 AVSTPSRMAHRDQE--WYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKA 216
V+T ++M +++ + + ++ +E +LL ++ ++Q A++EE + L K
Sbjct: 990 KVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLK- 1048
Query: 217 YKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNER 262
Y+ + L K ++ + K + + +S E E + +R
Sbjct: 1049 YEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQR 1094
Score = 35.8 bits (81), Expect = 0.049
Identities = 47/212 (22%), Positives = 93/212 (43%), Gaps = 26/212 (12%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQV--------AKQLQEEDLKAQAQLQKRYKDLEQQDC 85
+ +E LA+ Q LV +L+ ++Q+Q E + Q +Q+ LE ++
Sbjct: 922 EAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEG 981
Query: 86 EIAQEIQEKLAIEAERRRIQEK---KDEDIARLLQEKELQEEKKRKKHFPEFPATRAYAD 142
+ EK+ EA+ ++ +E ++ ++L +E++L E++ EF + A +
Sbjct: 982 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDR-----LAEFSSQAAEEE 1036
Query: 143 SYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQD 202
K R+ EA R +E + QE E L ++D ++++ Q+
Sbjct: 1037 EKVKSLN--KLRLKYEATIADMEDRLRKEE-------KGRQELEKLKRRLDGESSEL-QE 1086
Query: 203 EEIARLLMAEEKKAYKKAKEREKSSLDKRKQD 234
+ + + AEE +A KE E + R +D
Sbjct: 1087 QMVEQQQRAEELRAQLGRKEEELQAALARAED 1118
Score = 34.7 bits (78), Expect = 0.11
Identities = 44/212 (20%), Positives = 93/212 (43%), Gaps = 17/212 (8%)
Query: 50 RLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQ----QDCEIAQEIQEKLAIEAERRRIQ 105
R +Q +L A E+ + + L+K+ + +Q + + + ++E+ EAE R +
Sbjct: 1440 RRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 1499
Query: 106 EKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYY--YEDGGMKPRVMKEAVSTP 163
+ L +E+E +EE +R+ A RA ++ +D G ++ A
Sbjct: 1500 ARALSLTRALEEEQEAREELERQNR-----ALRAELEALLSSKDDVGKSVHELERACRVA 1554
Query: 164 SRMAHRDQEWYDAEIARKL--QEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAK 221
+ A+ D E+ +L E+ L +V ++A + + ++ A E++ + AK
Sbjct: 1555 EQAAN-DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAK 1613
Query: 222 EREKSSLDKRKQDPEWKPKTAKAANSKSKESD 253
+ + +++ D E K +T A K E +
Sbjct: 1614 QLRDAEVER---DEERKQRTLAVAARKKLEGE 1642
Score = 30.0 bits (66), Expect = 2.7
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 33 LQEQEIEHHLASNVQRNRL--VQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQE 90
LQEQ +E + R +L + +LQ A E++ A+AQL K ++ + E
Sbjct: 1084 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQ----AALAE 1139
Query: 91 IQEKLAIEAERRRIQEKKDEDIARLLQ 117
QE L E R EK+ D+ L+
Sbjct: 1140 AQEDLESERVARTKAEKQRRDLGEELE 1166
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 47.4 bits (111), Expect = 2e-05
Identities = 51/226 (22%), Positives = 110/226 (48%), Gaps = 26/226 (11%)
Query: 55 DLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEI--QEKLAIEAE--RRRIQEKK-- 108
+LQ ++LQ++ + +LQ R LE++ +A+++ + +L EAE R R+ +K
Sbjct: 918 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 977
Query: 109 -----DEDIARLLQEKE----LQEEKKR-KKHFPEFPATRAYADSYYYEDGGMKPRVMKE 158
E AR+ +E+E +Q EKKR ++H E +++ + G + ++ E
Sbjct: 978 LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQEL-------EAHLEAEEGARQKLQLE 1030
Query: 159 AVSTPSRMAHRDQE--WYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKA 216
V+T ++M +++ + + ++ +E +LL ++ ++Q A++EE + L K
Sbjct: 1031 KVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLK- 1089
Query: 217 YKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNER 262
Y+ + L K ++ + K + + +S E E + +R
Sbjct: 1090 YEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQR 1135
Score = 35.8 bits (81), Expect = 0.049
Identities = 47/212 (22%), Positives = 93/212 (43%), Gaps = 26/212 (12%)
Query: 34 QEQEIEHHLASNVQRNRLVQHDLQV--------AKQLQEEDLKAQAQLQKRYKDLEQQDC 85
+ +E LA+ Q LV +L+ ++Q+Q E + Q +Q+ LE ++
Sbjct: 963 EAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEG 1022
Query: 86 EIAQEIQEKLAIEAERRRIQEK---KDEDIARLLQEKELQEEKKRKKHFPEFPATRAYAD 142
+ EK+ EA+ ++ +E ++ ++L +E++L E++ EF + A +
Sbjct: 1023 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDR-----LAEFSSQAAEEE 1077
Query: 143 SYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQD 202
K R+ EA R +E + QE E L ++D ++++ Q+
Sbjct: 1078 EKVKSLN--KLRLKYEATIADMEDRLRKEE-------KGRQELEKLKRRLDGESSEL-QE 1127
Query: 203 EEIARLLMAEEKKAYKKAKEREKSSLDKRKQD 234
+ + + AEE +A KE E + R +D
Sbjct: 1128 QMVEQQQRAEELRAQLGRKEEELQAALARAED 1159
Score = 34.7 bits (78), Expect = 0.11
Identities = 44/212 (20%), Positives = 93/212 (43%), Gaps = 17/212 (8%)
Query: 50 RLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQ----QDCEIAQEIQEKLAIEAERRRIQ 105
R +Q +L A E+ + + L+K+ + +Q + + + ++E+ EAE R +
Sbjct: 1481 RRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 1540
Query: 106 EKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYY--YEDGGMKPRVMKEAVSTP 163
+ L +E+E +EE +R+ A RA ++ +D G ++ A
Sbjct: 1541 ARALSLTRALEEEQEAREELERQNR-----ALRAELEALLSSKDDVGKSVHELERACRVA 1595
Query: 164 SRMAHRDQEWYDAEIARKL--QEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAK 221
+ A+ D E+ +L E+ L +V ++A + + ++ A E++ + AK
Sbjct: 1596 EQAAN-DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAK 1654
Query: 222 EREKSSLDKRKQDPEWKPKTAKAANSKSKESD 253
+ + +++ D E K +T A K E +
Sbjct: 1655 QLRDAEVER---DEERKQRTLAVAARKKLEGE 1683
Score = 30.0 bits (66), Expect = 2.7
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 33 LQEQEIEHHLASNVQRNRL--VQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQE 90
LQEQ +E + R +L + +LQ A E++ A+AQL K ++ + E
Sbjct: 1125 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQ----AALAE 1180
Query: 91 IQEKLAIEAERRRIQEKKDEDIARLLQ 117
QE L E R EK+ D+ L+
Sbjct: 1181 AQEDLESERVARTKAEKQRRDLGEELE 1207
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 46.6 bits (109), Expect = 3e-05
Identities = 48/248 (19%), Positives = 103/248 (41%), Gaps = 11/248 (4%)
Query: 13 GVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHD--LQVAKQLQEEDLKAQ 70
G+ E+ + +D ++ + E E ++ H+ ++ K L+E+ ++ Q
Sbjct: 1121 GLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQ 1180
Query: 71 AQLQKRYKDLEQQDCEIAQEIQEKLA-----IEAERRRIQEKKDEDIARLLQEKELQEEK 125
++L LE+Q E + +EK +E +R+++ +++D +L+Q+ ++++
Sbjct: 1181 SKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDE 1240
Query: 126 KRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEE 185
+ EF R + E +K + A S D AE+ KLQEE
Sbjct: 1241 AIQTALKEFKLEREVVEKELLEK--VKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEE 1298
Query: 186 --ELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAK 243
+ L + + + + + L+AE++ + REK + D K K+
Sbjct: 1299 KAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTM 1358
Query: 244 AANSKSKE 251
+ K+
Sbjct: 1359 QQQERDKD 1366
Score = 33.1 bits (74), Expect = 0.32
Identities = 47/206 (22%), Positives = 85/206 (41%), Gaps = 22/206 (10%)
Query: 38 IEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAI 97
+E L + LV+H+ + LQ E +L + + Q+CEI + Q + +
Sbjct: 902 LEEVLQNKDNEFALVKHEKEAVICLQNEK---DQKLLEMENIMHSQNCEIKELKQSREIV 958
Query: 98 EAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMK 157
+ +++ + DE + L E + E+ H E T +E RV
Sbjct: 959 LEDLKKLHVENDEKLQLLRAELQSLEQ----SHLKELEDTLQVRHIQEFEKVMTDHRVSL 1014
Query: 158 EAVSTPSRMAHRDQEWYDAEI----ARKLQEEELLATQV-DMR-------AAQVAQDEEI 205
E + ++ + AEI ++LQE +L + + D R A + A+ +EI
Sbjct: 1015 EELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEI 1074
Query: 206 ARLL---MAEEKKAYKKAKEREKSSL 228
LL A++K+ K E+E +L
Sbjct: 1075 KILLEESRAQQKETLKSLLEQETENL 1100
Score = 28.5 bits (62), Expect = 7.8
Identities = 42/209 (20%), Positives = 80/209 (38%), Gaps = 28/209 (13%)
Query: 48 RNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDL--EQQDC-------------EIAQEIQ 92
+ +L + + +QL+E++ + ++Q L EQQ I ++
Sbjct: 1292 QEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLS 1351
Query: 93 EKLAIEAERRR----IQEKKDEDIARLLQEKELQEE---KKRKKHFPEFPATRAYADSYY 145
+KL +++ + E ED ARLL+EK+ EE K R F P + Y
Sbjct: 1352 DKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELY- 1410
Query: 146 YEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEI 205
G P + E S S + D+ D+ + + + + ++ E
Sbjct: 1411 ---GACAPELPGE--SDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIMLLERT 1465
Query: 206 ARLLMAEEKKAYKKAKEREKSSLDKRKQD 234
+L E K+ ++ + SS+ R +
Sbjct: 1466 LQLKEEENKRLNQRLMSQSMSSVSSRHSE 1494
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 46.6 bits (109), Expect = 3e-05
Identities = 48/248 (19%), Positives = 103/248 (41%), Gaps = 11/248 (4%)
Query: 13 GVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHD--LQVAKQLQEEDLKAQ 70
G+ E+ + +D ++ + E E ++ H+ ++ K L+E+ ++ Q
Sbjct: 1121 GLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQ 1180
Query: 71 AQLQKRYKDLEQQDCEIAQEIQEKLA-----IEAERRRIQEKKDEDIARLLQEKELQEEK 125
++L LE+Q E + +EK +E +R+++ +++D +L+Q+ ++++
Sbjct: 1181 SKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDE 1240
Query: 126 KRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEE 185
+ EF R + E +K + A S D AE+ KLQEE
Sbjct: 1241 AIQTALKEFKLEREVVEKELLEK--VKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEE 1298
Query: 186 --ELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAK 243
+ L + + + + + L+AE++ + REK + D K K+
Sbjct: 1299 KAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTM 1358
Query: 244 AANSKSKE 251
+ K+
Sbjct: 1359 QQQERDKD 1366
Score = 33.1 bits (74), Expect = 0.32
Identities = 47/206 (22%), Positives = 85/206 (41%), Gaps = 22/206 (10%)
Query: 38 IEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAI 97
+E L + LV+H+ + LQ E +L + + Q+CEI + Q + +
Sbjct: 902 LEEVLQNKDNEFALVKHEKEAVICLQNEK---DQKLLEMENIMHSQNCEIKELKQSREIV 958
Query: 98 EAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMK 157
+ +++ + DE + L E + E+ H E T +E RV
Sbjct: 959 LEDLKKLHVENDEKLQLLRAELQSLEQ----SHLKELEDTLQVRHIQEFEKVMTDHRVSL 1014
Query: 158 EAVSTPSRMAHRDQEWYDAEI----ARKLQEEELLATQV-DMR-------AAQVAQDEEI 205
E + ++ + AEI ++LQE +L + + D R A + A+ +EI
Sbjct: 1015 EELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEI 1074
Query: 206 ARLL---MAEEKKAYKKAKEREKSSL 228
LL A++K+ K E+E +L
Sbjct: 1075 KILLEESRAQQKETLKSLLEQETENL 1100
Score = 28.5 bits (62), Expect = 7.8
Identities = 42/209 (20%), Positives = 80/209 (38%), Gaps = 28/209 (13%)
Query: 48 RNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDL--EQQDC-------------EIAQEIQ 92
+ +L + + +QL+E++ + ++Q L EQQ I ++
Sbjct: 1292 QEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLS 1351
Query: 93 EKLAIEAERRR----IQEKKDEDIARLLQEKELQEE---KKRKKHFPEFPATRAYADSYY 145
+KL +++ + E ED ARLL+EK+ EE K R F P + Y
Sbjct: 1352 DKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELY- 1410
Query: 146 YEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEI 205
G P + E S S + D+ D+ + + + + ++ E
Sbjct: 1411 ---GACAPELPGE--SDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIMLLERT 1465
Query: 206 ARLLMAEEKKAYKKAKEREKSSLDKRKQD 234
+L E K+ ++ + SS+ R +
Sbjct: 1466 LQLKEEENKRLNQRLMSQSMSSVSSRHSE 1494
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.124 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,211,708
Number of Sequences: 37866
Number of extensions: 600494
Number of successful extensions: 9618
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 266
Number of HSP's successfully gapped in prelim test: 764
Number of HSP's that attempted gapping in prelim test: 4907
Number of HSP's gapped (non-prelim): 3385
length of query: 306
length of database: 18,247,518
effective HSP length: 102
effective length of query: 204
effective length of database: 14,385,186
effective search space: 2934577944
effective search space used: 2934577944
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.