Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 27886563
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 4 isoform 2 [Homo sapiens]
(902 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca... 1877 0.0
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c... 1832 0.0
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca... 591 e-168
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca... 591 e-168
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca... 591 e-168
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal... 591 e-168
gi|27502386 nuclear factor of activated T-cells, cytosolic compo... 439 e-123
gi|27886541 nuclear factor of activated T-cells, cytoplasmic, ca... 433 e-121
gi|27502391 nuclear factor of activated T-cells, cytosolic compo... 429 e-120
gi|27886539 nuclear factor of activated T-cells, cytoplasmic, ca... 429 e-120
gi|19923350 nuclear factor of activated T-cells, cytosolic compo... 427 e-119
gi|209862843 nuclear factor of activated T-cells, cytoplasmic, c... 426 e-119
gi|27502393 nuclear factor of activated T-cells, cytosolic compo... 414 e-115
gi|27502388 nuclear factor of activated T-cells, cytosolic compo... 304 3e-82
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 196 6e-50
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 196 6e-50
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho... 196 6e-50
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho... 196 6e-50
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom... 196 6e-50
gi|110832843 TBP-associated factor 4 [Homo sapiens] 69 3e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni... 65 4e-10
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 64 6e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 6e-10
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 62 2e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 62 2e-09
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 61 4e-09
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 61 4e-09
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 61 4e-09
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 59 2e-08
gi|33286446 opioid growth factor receptor [Homo sapiens] 59 3e-08
>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 4 isoform 2 [Homo sapiens]
Length = 902
Score = 1877 bits (4862), Expect = 0.0
Identities = 902/902 (100%), Positives = 902/902 (100%)
Query: 1 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG 60
MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG
Sbjct: 1 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG 60
Query: 61 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS 120
IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS
Sbjct: 61 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS 120
Query: 121 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS 180
ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS
Sbjct: 121 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS 180
Query: 181 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG 240
FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG
Sbjct: 181 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG 240
Query: 241 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP 300
RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP
Sbjct: 241 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP 300
Query: 301 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE 360
PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE
Sbjct: 301 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE 360
Query: 361 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR 420
SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR
Sbjct: 361 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR 420
Query: 421 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA 480
IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA
Sbjct: 421 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA 480
Query: 481 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE 540
FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE
Sbjct: 481 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE 540
Query: 541 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG 600
TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG
Sbjct: 541 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG 600
Query: 601 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR 660
GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR
Sbjct: 601 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR 660
Query: 661 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP 720
PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP
Sbjct: 661 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP 720
Query: 721 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV 780
PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV
Sbjct: 721 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV 780
Query: 781 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY 840
SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY
Sbjct: 781 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY 840
Query: 841 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEP 900
NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEP
Sbjct: 841 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEP 900
Query: 901 PA 902
PA
Sbjct: 901 PA 902
>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 4 isoform 1 [Homo sapiens]
Length = 964
Score = 1832 bits (4745), Expect = 0.0
Identities = 880/880 (100%), Positives = 880/880 (100%)
Query: 1 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG 60
MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG
Sbjct: 64 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG 123
Query: 61 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS 120
IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS
Sbjct: 124 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS 183
Query: 121 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS 180
ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS
Sbjct: 184 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS 243
Query: 181 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG 240
FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG
Sbjct: 244 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG 303
Query: 241 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP 300
RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP
Sbjct: 304 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP 363
Query: 301 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE 360
PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE
Sbjct: 364 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE 423
Query: 361 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR 420
SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR
Sbjct: 424 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR 483
Query: 421 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA 480
IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA
Sbjct: 484 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA 543
Query: 481 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE 540
FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE
Sbjct: 544 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE 603
Query: 541 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG 600
TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG
Sbjct: 604 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG 663
Query: 601 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR 660
GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR
Sbjct: 664 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR 723
Query: 661 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP 720
PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP
Sbjct: 724 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP 783
Query: 721 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV 780
PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV
Sbjct: 784 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV 843
Query: 781 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY 840
SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY
Sbjct: 844 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY 903
Query: 841 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEE 880
NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEE
Sbjct: 904 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEE 943
>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 1 [Homo sapiens]
Length = 1075
Score = 591 bits (1523), Expect = e-168
Identities = 368/783 (46%), Positives = 454/783 (57%), Gaps = 99/783 (12%)
Query: 1 MGAASC-EDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPI 59
M A+C +EL+FKLVFGE+ P G +L+ +D + PP P+
Sbjct: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
Query: 60 GIPRPPPPRPGMHSPPPRPAPS----PGTWESQPARSVRLGGPGGGAGGAGGGRVLECPS 115
+P P P S GT E ++ LGGP + ECPS
Sbjct: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGP----------KPFECPS 110
Query: 116 IRITSISPT-------PEPPAALEDNPDAWGDGSPRD--YPPPEGFGGYREAGGQGGGAF 166
I+ITSISP E + D + + RD Y P E YRE+
Sbjct: 111 IQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEP--SYRESS------- 161
Query: 167 FSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWT 226
SPSP +SS+SS S+FSDAS +L D+V+SELNEAA+RF LGSPL SP SP
Sbjct: 162 LSPSP-ASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220
Query: 227 PEDPW-SLYG------------PSPGGRGPEDSWLLLSAPGPTPAS---PRPASPCGKRR 270
E+ W YG SP +++WL P PAS RP SPCGKRR
Sbjct: 221 GEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWL-----SPRPASGPSSRPTSPCGKRR 275
Query: 271 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPL----------ARDPGSPG------P 314
+SS+ + GSL S P P P A G G P
Sbjct: 276 HSSA--------EVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFP 327
Query: 315 FDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGAEESVAPPGGS----R 369
F Y IP KTR+TS +QA LP E S + G L E S+ GS +
Sbjct: 328 FQYC---VETDIPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLK 384
Query: 370 KEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHH 429
K+ G +L+VPSP WSK + GH+PIFRTS+LPPLDWPLP+ + Q EL+IEVQP+ HH
Sbjct: 385 KDSCGDQFLSVPSPFTWSKPK-PGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHH 443
Query: 430 RAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITG 489
RAHYETEGSRGAVKA+ GGHPVVKLLGY+EKP+ LQMFIGTAD+R LRPHAFYQVHRITG
Sbjct: 444 RAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITG 503
Query: 490 KMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTR 549
K VATAS E +++ TKVLE+ LLPENNM+A+IDCAGILKLRNSDIELRKGETDIGRKNTR
Sbjct: 504 KTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTR 563
Query: 550 VRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGS 609
VRLVFRVH+PQ GKV+S+Q AS+P+ECSQRSAQELP +E YS ++CSV GG E+V+TGS
Sbjct: 564 VRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGS 623
Query: 610 NFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVS 669
NFLP+SK++F+E+G DG+ QWE E + R + + L VP Y N V+ VQV+FY+
Sbjct: 624 NFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLC 683
Query: 670 NGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHED 729
NG+RK+S +Q F + PV+ K+E + L PS P P P D
Sbjct: 684 NGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV-----------PHPAQTQRPSSD 732
Query: 730 PAC 732
C
Sbjct: 733 SGC 735
Score = 42.0 bits (97), Expect = 0.003
Identities = 43/159 (27%), Positives = 63/159 (39%), Gaps = 22/159 (13%)
Query: 752 TGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPF-SPPAP 810
TG P S + P G+ A P A P S P G S +P+ SP +
Sbjct: 903 TGQPSSQLQPITYGPSHSGSATTASPAA----SHPLASSPLSGPPSPQLQPMPYQSPSSG 958
Query: 811 FRPPPLPASPPLEGPFPSQSDVH-------PLPAEGYNKVGPGYGPGEGA-----PEQEK 858
P PA+ G +Q+ P ++ P P +GA PE E
Sbjct: 959 TASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPED 1018
Query: 859 SRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPG 897
+++ + +Q ITL++V+EIIGRD+S G
Sbjct: 1019 REPNFAT-----IGLQDITLDDVNEIIGRDMSQISVSQG 1052
>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 4 [Homo sapiens]
Length = 1045
Score = 591 bits (1523), Expect = e-168
Identities = 368/783 (46%), Positives = 454/783 (57%), Gaps = 99/783 (12%)
Query: 1 MGAASC-EDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPI 59
M A+C +EL+FKLVFGE+ P G +L+ +D + PP P+
Sbjct: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
Query: 60 GIPRPPPPRPGMHSPPPRPAPS----PGTWESQPARSVRLGGPGGGAGGAGGGRVLECPS 115
+P P P S GT E ++ LGGP + ECPS
Sbjct: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGP----------KPFECPS 110
Query: 116 IRITSISPT-------PEPPAALEDNPDAWGDGSPRD--YPPPEGFGGYREAGGQGGGAF 166
I+ITSISP E + D + + RD Y P E YRE+
Sbjct: 111 IQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEP--SYRESS------- 161
Query: 167 FSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWT 226
SPSP +SS+SS S+FSDAS +L D+V+SELNEAA+RF LGSPL SP SP
Sbjct: 162 LSPSP-ASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220
Query: 227 PEDPW-SLYG------------PSPGGRGPEDSWLLLSAPGPTPAS---PRPASPCGKRR 270
E+ W YG SP +++WL P PAS RP SPCGKRR
Sbjct: 221 GEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWL-----SPRPASGPSSRPTSPCGKRR 275
Query: 271 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPL----------ARDPGSPG------P 314
+SS+ + GSL S P P P A G G P
Sbjct: 276 HSSA--------EVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFP 327
Query: 315 FDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGAEESVAPPGGS----R 369
F Y IP KTR+TS +QA LP E S + G L E S+ GS +
Sbjct: 328 FQYC---VETDIPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLK 384
Query: 370 KEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHH 429
K+ G +L+VPSP WSK + GH+PIFRTS+LPPLDWPLP+ + Q EL+IEVQP+ HH
Sbjct: 385 KDSCGDQFLSVPSPFTWSKPK-PGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHH 443
Query: 430 RAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITG 489
RAHYETEGSRGAVKA+ GGHPVVKLLGY+EKP+ LQMFIGTAD+R LRPHAFYQVHRITG
Sbjct: 444 RAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITG 503
Query: 490 KMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTR 549
K VATAS E +++ TKVLE+ LLPENNM+A+IDCAGILKLRNSDIELRKGETDIGRKNTR
Sbjct: 504 KTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTR 563
Query: 550 VRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGS 609
VRLVFRVH+PQ GKV+S+Q AS+P+ECSQRSAQELP +E YS ++CSV GG E+V+TGS
Sbjct: 564 VRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGS 623
Query: 610 NFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVS 669
NFLP+SK++F+E+G DG+ QWE E + R + + L VP Y N V+ VQV+FY+
Sbjct: 624 NFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLC 683
Query: 670 NGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHED 729
NG+RK+S +Q F + PV+ K+E + L PS P P P D
Sbjct: 684 NGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV-----------PHPAQTQRPSSD 732
Query: 730 PAC 732
C
Sbjct: 733 SGC 735
>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 3 [Homo sapiens]
Length = 1065
Score = 591 bits (1523), Expect = e-168
Identities = 368/783 (46%), Positives = 454/783 (57%), Gaps = 99/783 (12%)
Query: 1 MGAASC-EDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPI 59
M A+C +EL+FKLVFGE+ P G +L+ +D + PP P+
Sbjct: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
Query: 60 GIPRPPPPRPGMHSPPPRPAPS----PGTWESQPARSVRLGGPGGGAGGAGGGRVLECPS 115
+P P P S GT E ++ LGGP + ECPS
Sbjct: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGP----------KPFECPS 110
Query: 116 IRITSISPT-------PEPPAALEDNPDAWGDGSPRD--YPPPEGFGGYREAGGQGGGAF 166
I+ITSISP E + D + + RD Y P E YRE+
Sbjct: 111 IQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEP--SYRESS------- 161
Query: 167 FSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWT 226
SPSP +SS+SS S+FSDAS +L D+V+SELNEAA+RF LGSPL SP SP
Sbjct: 162 LSPSP-ASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220
Query: 227 PEDPW-SLYG------------PSPGGRGPEDSWLLLSAPGPTPAS---PRPASPCGKRR 270
E+ W YG SP +++WL P PAS RP SPCGKRR
Sbjct: 221 GEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWL-----SPRPASGPSSRPTSPCGKRR 275
Query: 271 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPL----------ARDPGSPG------P 314
+SS+ + GSL S P P P A G G P
Sbjct: 276 HSSA--------EVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFP 327
Query: 315 FDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGAEESVAPPGGS----R 369
F Y IP KTR+TS +QA LP E S + G L E S+ GS +
Sbjct: 328 FQYC---VETDIPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLK 384
Query: 370 KEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHH 429
K+ G +L+VPSP WSK + GH+PIFRTS+LPPLDWPLP+ + Q EL+IEVQP+ HH
Sbjct: 385 KDSCGDQFLSVPSPFTWSKPK-PGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHH 443
Query: 430 RAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITG 489
RAHYETEGSRGAVKA+ GGHPVVKLLGY+EKP+ LQMFIGTAD+R LRPHAFYQVHRITG
Sbjct: 444 RAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITG 503
Query: 490 KMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTR 549
K VATAS E +++ TKVLE+ LLPENNM+A+IDCAGILKLRNSDIELRKGETDIGRKNTR
Sbjct: 504 KTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTR 563
Query: 550 VRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGS 609
VRLVFRVH+PQ GKV+S+Q AS+P+ECSQRSAQELP +E YS ++CSV GG E+V+TGS
Sbjct: 564 VRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGS 623
Query: 610 NFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVS 669
NFLP+SK++F+E+G DG+ QWE E + R + + L VP Y N V+ VQV+FY+
Sbjct: 624 NFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLC 683
Query: 670 NGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHED 729
NG+RK+S +Q F + PV+ K+E + L PS P P P D
Sbjct: 684 NGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV-----------PHPAQTQRPSSD 732
Query: 730 PAC 732
C
Sbjct: 733 SGC 735
>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 2 [Homo sapiens]
Length = 1068
Score = 591 bits (1523), Expect = e-168
Identities = 368/783 (46%), Positives = 454/783 (57%), Gaps = 99/783 (12%)
Query: 1 MGAASC-EDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPI 59
M A+C +EL+FKLVFGE+ P G +L+ +D + PP P+
Sbjct: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
Query: 60 GIPRPPPPRPGMHSPPPRPAPS----PGTWESQPARSVRLGGPGGGAGGAGGGRVLECPS 115
+P P P S GT E ++ LGGP + ECPS
Sbjct: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGP----------KPFECPS 110
Query: 116 IRITSISPT-------PEPPAALEDNPDAWGDGSPRD--YPPPEGFGGYREAGGQGGGAF 166
I+ITSISP E + D + + RD Y P E YRE+
Sbjct: 111 IQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEP--SYRESS------- 161
Query: 167 FSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWT 226
SPSP +SS+SS S+FSDAS +L D+V+SELNEAA+RF LGSPL SP SP
Sbjct: 162 LSPSP-ASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220
Query: 227 PEDPW-SLYG------------PSPGGRGPEDSWLLLSAPGPTPAS---PRPASPCGKRR 270
E+ W YG SP +++WL P PAS RP SPCGKRR
Sbjct: 221 GEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWL-----SPRPASGPSSRPTSPCGKRR 275
Query: 271 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPL----------ARDPGSPG------P 314
+SS+ + GSL S P P P A G G P
Sbjct: 276 HSSA--------EVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFP 327
Query: 315 FDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGAEESVAPPGGS----R 369
F Y IP KTR+TS +QA LP E S + G L E S+ GS +
Sbjct: 328 FQYC---VETDIPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLK 384
Query: 370 KEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHH 429
K+ G +L+VPSP WSK + GH+PIFRTS+LPPLDWPLP+ + Q EL+IEVQP+ HH
Sbjct: 385 KDSCGDQFLSVPSPFTWSKPK-PGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHH 443
Query: 430 RAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITG 489
RAHYETEGSRGAVKA+ GGHPVVKLLGY+EKP+ LQMFIGTAD+R LRPHAFYQVHRITG
Sbjct: 444 RAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITG 503
Query: 490 KMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTR 549
K VATAS E +++ TKVLE+ LLPENNM+A+IDCAGILKLRNSDIELRKGETDIGRKNTR
Sbjct: 504 KTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTR 563
Query: 550 VRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGS 609
VRLVFRVH+PQ GKV+S+Q AS+P+ECSQRSAQELP +E YS ++CSV GG E+V+TGS
Sbjct: 564 VRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGS 623
Query: 610 NFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVS 669
NFLP+SK++F+E+G DG+ QWE E + R + + L VP Y N V+ VQV+FY+
Sbjct: 624 NFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLC 683
Query: 670 NGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHED 729
NG+RK+S +Q F + PV+ K+E + L PS P P P D
Sbjct: 684 NGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV-----------PHPAQTQRPSSD 732
Query: 730 PAC 732
C
Sbjct: 733 SGC 735
>gi|27502386 nuclear factor of activated T-cells, cytosolic
component 1 isoform C [Homo sapiens]
Length = 930
Score = 439 bits (1129), Expect = e-123
Identities = 360/949 (37%), Positives = 439/949 (46%), Gaps = 164/949 (17%)
Query: 47 ALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGG 97
A P YG A + P P P HS P P + P + GG
Sbjct: 25 AAAAPEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGG 83
Query: 98 PGGGAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGF 152
P G +G G LE P I ITS +N + D D P
Sbjct: 84 PAGYFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP---- 133
Query: 153 GGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGL 211
+ SPS + SL S + D S A + SE + S +
Sbjct: 134 -----------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSY 182
Query: 212 G------SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLS 251
SP SP SP+ PE+ + +L G SP E+SWL
Sbjct: 183 PYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL--- 239
Query: 252 APGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGS 311
S RPASPC KR+YS +G SP S S P P + + D
Sbjct: 240 ----GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWL 288
Query: 312 PGPFDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLP 355
Y + + +P K+R+T+ EQ ++ EP + G P
Sbjct: 289 GNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPP 348
Query: 356 LGAEESVAPPGGS-----RKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPP 405
A+ AP S RK YLAVP P W+K + P+ TS LP
Sbjct: 349 PPAD--FAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPA 401
Query: 406 LDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTL 464
LDW LPS ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL L
Sbjct: 402 LDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLML 461
Query: 465 QMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCA 524
Q+FIGTAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCA
Sbjct: 462 QLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCA 521
Query: 525 GILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQE 584
GILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQ G+ +S+Q AS PIECSQRSAQE
Sbjct: 522 GILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQE 581
Query: 585 LPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEV 644
LP VE S + V GG+++VL+G NFL DSKV+F+E+ PDG WE EA +R
Sbjct: 582 LPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPN 641
Query: 645 TLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV---ICKEEPLPDSSLRGF 701
+L + +P + N+R++ PV V FYV NG+RKRS Q F +LP I K EP D
Sbjct: 642 SLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYE---- 697
Query: 702 PSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG----PPPS 757
P+ + P SP PY S P + L GF P PQ P
Sbjct: 698 PAPTCGP--VSQGLSPLPRPYYSQQLAMPPDPSSCLVAGF-----PPCPQRSTLMPAAPG 750
Query: 758 YRPGLRMFPETRGTTGCAQP--------------PAVSFLPRPFPSDPYGGRGSSFSLGL 803
P L T G A P PAV +PRP + P G
Sbjct: 751 VSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP----------GS 800
Query: 804 PFSPPAPFRP-----PPLPASPP-LEGPFPSQSDVHPLPAEGYNKV-----GPGYGPGEG 852
P PP P PP + PP LE S PLP P P G
Sbjct: 801 PGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPACPPATG 860
Query: 853 APEQEKSRGGYSSGFRDSVPIQG-ITLEEVSEIIGRDLSGFPAPPGEEP 900
P+ S+ RD P G L EV E +L+ P EP
Sbjct: 861 RPQHLP-----STVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTVKREP 904
Score = 30.4 bits (67), Expect = 7.8
Identities = 52/211 (24%), Positives = 74/211 (35%), Gaps = 55/211 (26%)
Query: 711 TDMDFSPPR------PPYPSYPHEDPACETPYLSEG---------FGYGMPPLYP--QTG 753
TD D P PP+ + P + Y+ G F Y +P P +T
Sbjct: 633 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTY-LPANVPIIKTE 691
Query: 754 PPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRP 813
P Y P P ++G +S LPRP+ S S + PP P R
Sbjct: 692 PTDDYEPAPTCGPVSQG---------LSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRS 742
Query: 814 PPLPASPPLEGPFPSQSDVHPLPAEGYNK--VGPGYGPGEGAPEQEKSRGGYSSGFRDSV 871
+PA+P G P D+ P Y K PG+ G P+ G + +D
Sbjct: 743 TLMPAAP---GVSPKLHDLSPA---AYTKGVASPGHCH-LGLPQP----AGEAPAVQD-- 789
Query: 872 PIQGITLEEVSEIIGRDLSGFPAPPGEEPPA 902
+ R ++ P PG+ PPA
Sbjct: 790 -------------VPRPVATHPGSPGQPPPA 807
>gi|27886541 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform C [Homo sapiens]
Length = 925
Score = 433 bits (1114), Expect = e-121
Identities = 363/969 (37%), Positives = 461/969 (47%), Gaps = 156/969 (16%)
Query: 9 EELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIGIP----RP 64
+EL+F ++F E P +E+ P ++A PP A P + +P
Sbjct: 26 DELDFSILFDYEYLNP------------NEEEPNAHKVA--SPPSGPAYPDDVLDYGLKP 71
Query: 65 PPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIR-ITSISP 123
P + PP P P + + P G +G + R+ PS I ++ P
Sbjct: 72 YSPLASLSGEPPGRFGEPD--RVGPQKFLSAAKPAGASGLSP--RIEITPSHELIQAVGP 127
Query: 124 TPEPPAAL--EDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSF 181
A L E P A SPR P GF GYRE SP SS SS SF
Sbjct: 128 LRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP--------LCLSPASSG-SSASF 178
Query: 182 FSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGGR 241
SD SP SP SP P+D + P
Sbjct: 179 ISDTF--------------------------SPYTSPCVSPNNGGPDDLCPQFQNIPAHY 212
Query: 242 GP-------------EDSWLLLSAPGPTPASPRPASPCGKRRYSSS----GTPSSASPAL 284
P EDS L +P P PAS R +SP KRR+S + P ASP
Sbjct: 213 SPRTSPIMSPRTSLAEDSCLGRHSPVPRPAS-RSSSPGAKRRHSCAEALVALPPGASPQR 271
Query: 285 SRRGSLGEEGSEPPPPPPLPLARDP--GSPGPFDYVGAPPAES---IPQKTRRTSSEQAV 339
SR S P P P GS D + + +S IP K +TS + +
Sbjct: 272 SRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPS- 330
Query: 340 ALPRSEEPASCNGKLP---LGAEESVAP-PGGSRKEVAGMDYLAVPSPLAWSKARIGGHS 395
P S P+ LP A E + P G R+ A L VP W K +
Sbjct: 331 --PVSAAPSKAG--LPRHIYPAVEFLGPCEQGERRNSAPESILLVPP--TWPKPLVPA-I 383
Query: 396 PIFR---TSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVV 452
PI T++LPPL+WPL SQ ELRIEVQP+ HHRAHYETEGSRGAVKA GGHPVV
Sbjct: 384 PICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVV 443
Query: 453 KLLGYSE-KPLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTL 511
+L GY E KPL LQ+FIGTADER L+PHAFYQVHRITGK V T SYE +V TKVLE+ L
Sbjct: 444 QLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPL 503
Query: 512 LPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAA 571
P+NNM A IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ G++VS+Q A
Sbjct: 504 EPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTA 563
Query: 572 SVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWE 631
S PIECSQRSA ELP VE +C V GG++++LTG NF +SKVVF E+ DG+ WE
Sbjct: 564 SNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWE 623
Query: 632 EEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV-ICKE 690
EATV++ +S L + +PEY NK + PV+V FYV NG+RKRS Q F + PV K
Sbjct: 624 MEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKT 683
Query: 691 EPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLS--EGFGYGM--- 745
EP + P+ +P + P P +P E P+C ++ + F G+
Sbjct: 684 EPTDEYD----PTLICSPTHGGLGSQPYYPQHPMVA-ESPSCLVATMAPCQQFRTGLSSP 738
Query: 746 PPLYPQTGPPP-SYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPY-------GGRGS 797
Y Q P Y+ + P G Q PA+ P +D + G +G
Sbjct: 739 DARYQQQNPAAVLYQRSKSLSPSLLG----YQQPALMAAPLSL-ADAHRSVLVHAGSQGQ 793
Query: 798 SFSLGLPFSPPAPFRPPPLPASPP-----------------LEGPFPSQSDVHPLPAEGY 840
S +L P SP P + SP E P + P P
Sbjct: 794 SSALLHP-SPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFAPGTTRPGPPPVSQG 852
Query: 841 NKVGPGYGP----GEGAPEQEKSRGGYSSGFRDSVPIQGIT-----------LEEVSEII 885
++ PG P + A Q ++ G + V G+T L++V+EII
Sbjct: 853 QRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNLDQTYLDDVNEII 912
Query: 886 GRDLSGFPA 894
++ SG PA
Sbjct: 913 RKEFSGPPA 921
>gi|27502391 nuclear factor of activated T-cells, cytosolic
component 1 isoform E [Homo sapiens]
Length = 812
Score = 429 bits (1104), Expect = e-120
Identities = 333/850 (39%), Positives = 407/850 (47%), Gaps = 147/850 (17%)
Query: 47 ALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGG 97
A P YG A + P P P HS P P + P + GG
Sbjct: 25 AAAAPEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGG 83
Query: 98 PGGGAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGF 152
P G +G G LE P I ITS +N + D D P
Sbjct: 84 PAGYFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP---- 133
Query: 153 GGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGL 211
+ SPS + SL S + D S A + SE + S +
Sbjct: 134 -----------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSY 182
Query: 212 G------SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLS 251
SP SP SP+ PE+ + +L G SP E+SWL
Sbjct: 183 PYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL--- 239
Query: 252 APGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGS 311
S RPASPC KR+YS +G SP S S P P + + D
Sbjct: 240 ----GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWL 288
Query: 312 PGPFDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLP 355
Y + + +P K+R+T+ EQ ++ EP + G P
Sbjct: 289 GNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPP 348
Query: 356 LGAEESVAPPGGS-----RKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPP 405
A+ AP S RK YLAVP P W+K + P+ TS LP
Sbjct: 349 PPAD--FAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPA 401
Query: 406 LDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTL 464
LDW LPS ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL L
Sbjct: 402 LDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLML 461
Query: 465 QMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCA 524
Q+FIGTAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCA
Sbjct: 462 QLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCA 521
Query: 525 GILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQE 584
GILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQ G+ +S+Q AS PIECSQRSAQE
Sbjct: 522 GILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQE 581
Query: 585 LPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEV 644
LP VE S + V GG+++VL+G NFL DSKV+F+E+ PDG WE EA +R
Sbjct: 582 LPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPN 641
Query: 645 TLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV---ICKEEPLPDSSLRGF 701
+L + +P + N+R++ PV V FYV NG+RKRS Q F +LP I K EP D
Sbjct: 642 SLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYE---- 697
Query: 702 PSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG----PPPS 757
P+ + P SP PY S P + L GF P PQ P
Sbjct: 698 PAPTCGP--VSQGLSPLPRPYYSQQLAMPPDPSSCLVAGF-----PPCPQRSTLMPAAPG 750
Query: 758 YRPGLRMFPETRGTTGCAQP--------------PAVSFLPRPFPSDPYGGRGSSFSLGL 803
P L T G A P PAV +PRP + P G
Sbjct: 751 VSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP----------GS 800
Query: 804 PFSPPAPFRP 813
P PP P
Sbjct: 801 PGQPPPALLP 810
Score = 30.4 bits (67), Expect = 7.8
Identities = 52/211 (24%), Positives = 74/211 (35%), Gaps = 55/211 (26%)
Query: 711 TDMDFSPPR------PPYPSYPHEDPACETPYLSEG---------FGYGMPPLYP--QTG 753
TD D P PP+ + P + Y+ G F Y +P P +T
Sbjct: 633 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTY-LPANVPIIKTE 691
Query: 754 PPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRP 813
P Y P P ++G +S LPRP+ S S + PP P R
Sbjct: 692 PTDDYEPAPTCGPVSQG---------LSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRS 742
Query: 814 PPLPASPPLEGPFPSQSDVHPLPAEGYNK--VGPGYGPGEGAPEQEKSRGGYSSGFRDSV 871
+PA+P G P D+ P Y K PG+ G P+ G + +D
Sbjct: 743 TLMPAAP---GVSPKLHDLSPA---AYTKGVASPGHCH-LGLPQP----AGEAPAVQD-- 789
Query: 872 PIQGITLEEVSEIIGRDLSGFPAPPGEEPPA 902
+ R ++ P PG+ PPA
Sbjct: 790 -------------VPRPVATHPGSPGQPPPA 807
>gi|27886539 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform B [Homo sapiens]
Length = 921
Score = 429 bits (1103), Expect = e-120
Identities = 318/762 (41%), Positives = 391/762 (51%), Gaps = 105/762 (13%)
Query: 9 EELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIGIP----RP 64
+EL+F ++F E P +E+ P ++A PP A P + +P
Sbjct: 26 DELDFSILFDYEYLNP------------NEEEPNAHKVA--SPPSGPAYPDDVLDYGLKP 71
Query: 65 PPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIR-ITSISP 123
P + PP P P + + P G +G + R+ PS I ++ P
Sbjct: 72 YSPLASLSGEPPGRFGEPD--RVGPQKFLSAAKPAGASGLSP--RIEITPSHELIQAVGP 127
Query: 124 TPEPPAAL--EDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSF 181
A L E P A SPR P GF GYRE SP SS SS SF
Sbjct: 128 LRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP--------LCLSPASSG-SSASF 178
Query: 182 FSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGGR 241
SD SP SP SP P+D + P
Sbjct: 179 ISDTF--------------------------SPYTSPCVSPNNGGPDDLCPQFQNIPAHY 212
Query: 242 GP-------------EDSWLLLSAPGPTPASPRPASPCGKRRYSSS----GTPSSASPAL 284
P EDS L +P P PAS R +SP KRR+S + P ASP
Sbjct: 213 SPRTSPIMSPRTSLAEDSCLGRHSPVPRPAS-RSSSPGAKRRHSCAEALVALPPGASPQR 271
Query: 285 SRRGSLGEEGSEPPPPPPLPLARDP--GSPGPFDYVGAPPAES---IPQKTRRTSSEQAV 339
SR S P P P GS D + + +S IP K +TS + +
Sbjct: 272 SRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPS- 330
Query: 340 ALPRSEEPASCNGKLP---LGAEESVAP-PGGSRKEVAGMDYLAVPSPLAWSKARIGGHS 395
P S P+ LP A E + P G R+ A L VP W K +
Sbjct: 331 --PVSAAPSKAG--LPRHIYPAVEFLGPCEQGERRNSAPESILLVPP--TWPKPLVPA-I 383
Query: 396 PIFR---TSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVV 452
PI T++LPPL+WPL SQ ELRIEVQP+ HHRAHYETEGSRGAVKA GGHPVV
Sbjct: 384 PICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVV 443
Query: 453 KLLGYSE-KPLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTL 511
+L GY E KPL LQ+FIGTADER L+PHAFYQVHRITGK V T SYE +V TKVLE+ L
Sbjct: 444 QLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPL 503
Query: 512 LPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAA 571
P+NNM A IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ G++VS+Q A
Sbjct: 504 EPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTA 563
Query: 572 SVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWE 631
S PIECSQRSA ELP VE +C V GG++++LTG NF +SKVVF E+ DG+ WE
Sbjct: 564 SNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWE 623
Query: 632 EEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV-ICKE 690
EATV++ +S L + +PEY NK + PV+V FYV NG+RKRS Q F + PV K
Sbjct: 624 MEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKT 683
Query: 691 EPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPAC 732
EP + P+ +P + P P +P E P+C
Sbjct: 684 EPTDEYD----PTLICSPTHGGLGSQPYYPQHPMVA-ESPSC 720
>gi|19923350 nuclear factor of activated T-cells, cytosolic
component 1 isoform B [Homo sapiens]
Length = 825
Score = 427 bits (1099), Expect = e-119
Identities = 332/847 (39%), Positives = 406/847 (47%), Gaps = 147/847 (17%)
Query: 50 EPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGGPGG 100
E YG A + P P P HS P P + P + GGP G
Sbjct: 41 EEEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAG 99
Query: 101 GAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGY 155
+G G LE P I ITS +N + D D P
Sbjct: 100 YFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP------- 146
Query: 156 REAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGLG-- 212
+ SPS + SL S + D S A + SE + S +
Sbjct: 147 --------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYA 198
Query: 213 ----SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLSAPG 254
SP SP SP+ PE+ + +L G SP E+SWL
Sbjct: 199 SPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL------ 252
Query: 255 PTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGP 314
S RPASPC KR+YS +G SP S S P P + + D
Sbjct: 253 -GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWLGNT 304
Query: 315 FDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGA 358
Y + + +P K+R+T+ EQ ++ EP + G P A
Sbjct: 305 TQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPA 364
Query: 359 EESVAPPGGS-----RKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPPLDW 408
+ AP S RK YLAVP P W+K + P+ TS LP LDW
Sbjct: 365 D--FAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPALDW 417
Query: 409 PLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTLQMF 467
LPS ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL LQ+F
Sbjct: 418 QLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLF 477
Query: 468 IGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGIL 527
IGTAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCAGIL
Sbjct: 478 IGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGIL 537
Query: 528 KLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQ 587
KLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQ G+ +S+Q AS PIECSQRSAQELP
Sbjct: 538 KLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPL 597
Query: 588 VEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLT 647
VE S + V GG+++VL+G NFL DSKV+F+E+ PDG WE EA +R +L
Sbjct: 598 VEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLV 657
Query: 648 LTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV---ICKEEPLPDSSLRGFPSA 704
+ +P + N+R++ PV V FYV NG+RKRS Q F +LP I K EP D P+
Sbjct: 658 VEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYE----PAP 713
Query: 705 SATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG----PPPSYRP 760
+ P SP PY S P + L GF P PQ P P
Sbjct: 714 TCGP--VSQGLSPLPRPYYSQQLAMPPDPSSCLVAGF-----PPCPQRSTLMPAAPGVSP 766
Query: 761 GLRMFPETRGTTGCAQP--------------PAVSFLPRPFPSDPYGGRGSSFSLGLPFS 806
L T G A P PAV +PRP + P G P
Sbjct: 767 KLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP----------GSPGQ 816
Query: 807 PPAPFRP 813
PP P
Sbjct: 817 PPPALLP 823
Score = 30.4 bits (67), Expect = 7.8
Identities = 52/211 (24%), Positives = 74/211 (35%), Gaps = 55/211 (26%)
Query: 711 TDMDFSPPR------PPYPSYPHEDPACETPYLSEG---------FGYGMPPLYP--QTG 753
TD D P PP+ + P + Y+ G F Y +P P +T
Sbjct: 646 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTY-LPANVPIIKTE 704
Query: 754 PPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRP 813
P Y P P ++G +S LPRP+ S S + PP P R
Sbjct: 705 PTDDYEPAPTCGPVSQG---------LSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRS 755
Query: 814 PPLPASPPLEGPFPSQSDVHPLPAEGYNK--VGPGYGPGEGAPEQEKSRGGYSSGFRDSV 871
+PA+P G P D+ P Y K PG+ G P+ G + +D
Sbjct: 756 TLMPAAP---GVSPKLHDLSPA---AYTKGVASPGHCH-LGLPQP----AGEAPAVQD-- 802
Query: 872 PIQGITLEEVSEIIGRDLSGFPAPPGEEPPA 902
+ R ++ P PG+ PPA
Sbjct: 803 -------------VPRPVATHPGSPGQPPPA 820
>gi|209862843 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform D [Homo sapiens]
Length = 901
Score = 426 bits (1096), Expect = e-119
Identities = 306/698 (43%), Positives = 366/698 (52%), Gaps = 94/698 (13%)
Query: 69 PGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIR-ITSISPTPEP 127
PG P R P ++PA GA G R+ PS I ++ P
Sbjct: 63 PGRFGEPDRVGPQKFLSAAKPA----------GASGLSP-RIEITPSHELIQAVGPLRMR 111
Query: 128 PAAL--EDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDA 185
A L E P A SPR P GF GYRE SP SS SS SF SD
Sbjct: 112 DAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP--------LCLSPASSG-SSASFISDT 162
Query: 186 SDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGP-- 243
SP SP SP P+D + P P
Sbjct: 163 F--------------------------SPYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRT 196
Query: 244 -----------EDSWLLLSAPGPTPASPRPASPCGKRRYSSS----GTPSSASPALSRRG 288
EDS L +P P PAS R +SP KRR+S + P ASP SR
Sbjct: 197 SPIMSPRTSLAEDSCLGRHSPVPRPAS-RSSSPGAKRRHSCAEALVALPPGASPQRSRSP 255
Query: 289 SLGEEGSEPPPPPPLPLARDP--GSPGPFDYVGAPPAES---IPQKTRRTSSEQAVALPR 343
S P P P GS D + + +S IP K +TS + + P
Sbjct: 256 SPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPS---PV 312
Query: 344 SEEPASCNGKLP---LGAEESVAP-PGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFR 399
S P+ LP A E + P G R+ A L VP W K + PI
Sbjct: 313 SAAPSKAG--LPRHIYPAVEFLGPCEQGERRNSAPESILLVPP--TWPKPLVPA-IPICS 367
Query: 400 ---TSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLG 456
T++LPPL+WPL SQ ELRIEVQP+ HHRAHYETEGSRGAVKA GGHPVV+L G
Sbjct: 368 IPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHG 427
Query: 457 YSE-KPLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPEN 515
Y E KPL LQ+FIGTADER L+PHAFYQVHRITGK V T SYE +V TKVLE+ L P+N
Sbjct: 428 YMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKN 487
Query: 516 NMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPI 575
NM A IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ G++VS+Q AS PI
Sbjct: 488 NMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPI 547
Query: 576 ECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEAT 635
ECSQRSA ELP VE +C V GG++++LTG NF +SKVVF E+ DG+ WE EAT
Sbjct: 548 ECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEAT 607
Query: 636 VNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV-ICKEEPLP 694
V++ +S L + +PEY NK + PV+V FYV NG+RKRS Q F + PV K EP
Sbjct: 608 VDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKTEPTD 667
Query: 695 DSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPAC 732
+ P+ +P + P P +P E P+C
Sbjct: 668 EYD----PTLICSPTHGGLGSQPYYPQHPMVA-ESPSC 700
>gi|27502393 nuclear factor of activated T-cells, cytosolic
component 1 isoform A [Homo sapiens]
Length = 716
Score = 414 bits (1064), Expect = e-115
Identities = 294/698 (42%), Positives = 363/698 (52%), Gaps = 105/698 (15%)
Query: 50 EPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGGPGG 100
E YG A + P P P HS P P + P + GGP G
Sbjct: 41 EEEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAG 99
Query: 101 GAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGY 155
+G G LE P I ITS +N + D D P
Sbjct: 100 YFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP------- 146
Query: 156 REAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGLG-- 212
+ SPS + SL S + D S A + SE + S +
Sbjct: 147 --------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYA 198
Query: 213 ----SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLSAPG 254
SP SP SP+ PE+ + +L G SP E+SWL
Sbjct: 199 SPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL------ 252
Query: 255 PTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGP 314
S RPASPC KR+YS +G SP S S P P + + D
Sbjct: 253 -GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWLGNT 304
Query: 315 FDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGA 358
Y + + +P K+R+T+ EQ ++ EP + G P A
Sbjct: 305 TQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPA 364
Query: 359 EESVAPPGGS-----RKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPPLDW 408
+ AP S RK YLAVP P W+K + P+ TS LP LDW
Sbjct: 365 D--FAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPALDW 417
Query: 409 PLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTLQMF 467
LPS ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL LQ+F
Sbjct: 418 QLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLF 477
Query: 468 IGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGIL 527
IGTAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCAGIL
Sbjct: 478 IGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGIL 537
Query: 528 KLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQ 587
KLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQ G+ +S+Q AS PIECSQRSAQELP
Sbjct: 538 KLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPL 597
Query: 588 VEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLT 647
VE S + V GG+++VL+G NFL DSKV+F+E+ PDG WE EA +R +L
Sbjct: 598 VEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLV 657
Query: 648 LTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLP 685
+ +P + N+R++ PV V FYV NG+RKRS Q F +LP
Sbjct: 658 VEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
>gi|27502388 nuclear factor of activated T-cells, cytosolic
component 1 isoform D [Homo sapiens]
Length = 353
Score = 304 bits (778), Expect = 3e-82
Identities = 184/371 (49%), Positives = 218/371 (58%), Gaps = 42/371 (11%)
Query: 464 LQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDC 523
LQ+FIGTAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDC
Sbjct: 2 LQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDC 61
Query: 524 AGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQ 583
AGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQ G+ +S+Q AS PIECSQRSAQ
Sbjct: 62 AGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQ 121
Query: 584 ELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNE 643
ELP VE S + V GG+++VL+G NFL DSKV+F+E+ PDG WE EA +R
Sbjct: 122 ELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKP 181
Query: 644 VTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPV---ICKEEPLPDSSLRG 700
+L + +P + N+R++ PV V FYV NG+RKRS Q F +LP I K EP D
Sbjct: 182 NSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYE--- 238
Query: 701 FPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG----PPP 756
P+ + P SP PY S P + L GF P PQ P
Sbjct: 239 -PAPTCGP--VSQGLSPLPRPYYSQQLAMPPDPSSCLVAGF-----PPCPQRSTLMPAAP 290
Query: 757 SYRPGLRMFPETRGTTGCAQP--------------PAVSFLPRPFPSDPYGGRGSSFSLG 802
P L T G A P PAV +PRP + P G
Sbjct: 291 GVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHP----------G 340
Query: 803 LPFSPPAPFRP 813
P PP P
Sbjct: 341 SPGQPPPALLP 351
Score = 37.0 bits (84), Expect = 0.083
Identities = 40/120 (33%), Positives = 51/120 (42%), Gaps = 20/120 (16%)
Query: 213 SPLPSPRASPRPWTPEDPWS--LYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRR 270
SPLP P S + P DP S + G P P+ S L+ +APG +P SP
Sbjct: 251 SPLPRPYYSQQLAMPPDPSSCLVAGFPPC---PQRSTLMPAAPGVSPKL-HDLSP----- 301
Query: 271 YSSSGTPSSASPALSRRGSLGEEGSEPPPPP-PLPLARDPGSPGPFDYVGAPPAESIPQK 329
++ T ASP G G P P P+A PGSP G PP +PQ+
Sbjct: 302 --AAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSP------GQPPPALLPQQ 353
Score = 30.4 bits (67), Expect = 7.8
Identities = 52/211 (24%), Positives = 74/211 (35%), Gaps = 55/211 (26%)
Query: 711 TDMDFSPPR------PPYPSYPHEDPACETPYLSEG---------FGYGMPPLYP--QTG 753
TD D P PP+ + P + Y+ G F Y +P P +T
Sbjct: 174 TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTY-LPANVPIIKTE 232
Query: 754 PPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRP 813
P Y P P ++G +S LPRP+ S S + PP P R
Sbjct: 233 PTDDYEPAPTCGPVSQG---------LSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRS 283
Query: 814 PPLPASPPLEGPFPSQSDVHPLPAEGYNK--VGPGYGPGEGAPEQEKSRGGYSSGFRDSV 871
+PA+P G P D+ P Y K PG+ G P+ G + +D
Sbjct: 284 TLMPAAP---GVSPKLHDLSPA---AYTKGVASPGHCH-LGLPQP----AGEAPAVQD-- 330
Query: 872 PIQGITLEEVSEIIGRDLSGFPAPPGEEPPA 902
+ R ++ P PG+ PPA
Sbjct: 331 -------------VPRPVATHPGSPGQPPPA 348
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 196 bits (499), Expect = 6e-50
Identities = 116/283 (40%), Positives = 165/283 (58%), Gaps = 7/283 (2%)
Query: 404 PPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVK-AAPGGHPVVKLLGYSEKPL 462
P L P + E EL+I VQP HRA Y TEGSRG+VK G P VKL G++E P+
Sbjct: 191 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNE-PV 249
Query: 463 TLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANID 522
LQ+F+G D ++PH FYQ R+TG+ T E + GT V+E+ L P NNM +D
Sbjct: 250 VLQVFVGN-DSGRVKPHGFYQACRVTGRNT-TPCKEVDIEGTTVIEVGLDPSNNMTLAVD 307
Query: 523 CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSA 582
C GILKLRN+D+E R G +K+TR RLVFRV++ + G +++Q S PI C+Q +
Sbjct: 308 CVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG 367
Query: 583 QELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSN 642
+P++ S +CSV+G EE+ L G NFL +KV+F E D + W+ EA ++ +
Sbjct: 368 --VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFH 424
Query: 643 EVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLP 685
+ L + VP Y ++ ++ PV V YV + Q F + P
Sbjct: 425 QNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 467
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 196 bits (499), Expect = 6e-50
Identities = 116/283 (40%), Positives = 165/283 (58%), Gaps = 7/283 (2%)
Query: 404 PPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVK-AAPGGHPVVKLLGYSEKPL 462
P L P + E EL+I VQP HRA Y TEGSRG+VK G P VKL G++E P+
Sbjct: 267 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNE-PV 325
Query: 463 TLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANID 522
LQ+F+G D ++PH FYQ R+TG+ T E + GT V+E+ L P NNM +D
Sbjct: 326 VLQVFVGN-DSGRVKPHGFYQACRVTGRNT-TPCKEVDIEGTTVIEVGLDPSNNMTLAVD 383
Query: 523 CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSA 582
C GILKLRN+D+E R G +K+TR RLVFRV++ + G +++Q S PI C+Q +
Sbjct: 384 CVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG 443
Query: 583 QELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSN 642
+P++ S +CSV+G EE+ L G NFL +KV+F E D + W+ EA ++ +
Sbjct: 444 --VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFH 500
Query: 643 EVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLP 685
+ L + VP Y ++ ++ PV V YV + Q F + P
Sbjct: 501 QNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 543
>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
sapiens]
Length = 1548
Score = 196 bits (499), Expect = 6e-50
Identities = 116/283 (40%), Positives = 165/283 (58%), Gaps = 7/283 (2%)
Query: 404 PPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVK-AAPGGHPVVKLLGYSEKPL 462
P L P + E EL+I VQP HRA Y TEGSRG+VK G P VKL G++E P+
Sbjct: 285 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNE-PV 343
Query: 463 TLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANID 522
LQ+F+G D ++PH FYQ R+TG+ T E + GT V+E+ L P NNM +D
Sbjct: 344 VLQVFVGN-DSGRVKPHGFYQACRVTGRNT-TPCKEVDIEGTTVIEVGLDPSNNMTLAVD 401
Query: 523 CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSA 582
C GILKLRN+D+E R G +K+TR RLVFRV++ + G +++Q S PI C+Q +
Sbjct: 402 CVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG 461
Query: 583 QELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSN 642
+P++ S +CSV+G EE+ L G NFL +KV+F E D + W+ EA ++ +
Sbjct: 462 --VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFH 518
Query: 643 EVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLP 685
+ L + VP Y ++ ++ PV V YV + Q F + P
Sbjct: 519 QNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 561
>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
sapiens]
Length = 1549
Score = 196 bits (499), Expect = 6e-50
Identities = 116/283 (40%), Positives = 165/283 (58%), Gaps = 7/283 (2%)
Query: 404 PPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVK-AAPGGHPVVKLLGYSEKPL 462
P L P + E EL+I VQP HRA Y TEGSRG+VK G P VKL G++E P+
Sbjct: 285 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNE-PV 343
Query: 463 TLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANID 522
LQ+F+G D ++PH FYQ R+TG+ T E + GT V+E+ L P NNM +D
Sbjct: 344 VLQVFVGN-DSGRVKPHGFYQACRVTGRNT-TPCKEVDIEGTTVIEVGLDPSNNMTLAVD 401
Query: 523 CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSA 582
C GILKLRN+D+E R G +K+TR RLVFRV++ + G +++Q S PI C+Q +
Sbjct: 402 CVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG 461
Query: 583 QELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSN 642
+P++ S +CSV+G EE+ L G NFL +KV+F E D + W+ EA ++ +
Sbjct: 462 --VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFH 518
Query: 643 EVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLP 685
+ L + VP Y ++ ++ PV V YV + Q F + P
Sbjct: 519 QNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 561
>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 196 bits (499), Expect = 6e-50
Identities = 116/283 (40%), Positives = 165/283 (58%), Gaps = 7/283 (2%)
Query: 404 PPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVK-AAPGGHPVVKLLGYSEKPL 462
P L P + E EL+I VQP HRA Y TEGSRG+VK G P VKL G++E P+
Sbjct: 191 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNE-PV 249
Query: 463 TLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANID 522
LQ+F+G D ++PH FYQ R+TG+ T E + GT V+E+ L P NNM +D
Sbjct: 250 VLQVFVGN-DSGRVKPHGFYQACRVTGRNT-TPCKEVDIEGTTVIEVGLDPSNNMTLAVD 307
Query: 523 CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSA 582
C GILKLRN+D+E R G +K+TR RLVFRV++ + G +++Q S PI C+Q +
Sbjct: 308 CVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG 367
Query: 583 QELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSN 642
+P++ S +CSV+G EE+ L G NFL +KV+F E D + W+ EA ++ +
Sbjct: 368 --VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFH 424
Query: 643 EVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLP 685
+ L + VP Y ++ ++ PV V YV + Q F + P
Sbjct: 425 QNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 467
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 68.6 bits (166), Expect = 3e-11
Identities = 96/352 (27%), Positives = 120/352 (34%), Gaps = 53/352 (15%)
Query: 25 PLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG---IPRPPPPRPGMHSPPPRPAPS 81
P GA G G +E AP A EPPP G A G RP PP P P PAP
Sbjct: 67 PAGAAGAGPAAPAEGAPG----AAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP- 121
Query: 82 PGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDG 141
PA +R P G AG P +++ PEP A P
Sbjct: 122 -------PAAKLR-PPPEGSAGSCA-------PVPAAAAVAAGPEPAPAGPAKPAGPAAL 166
Query: 142 SPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAAL----YAACDE 197
+ R P P G G G P PG + + AAL +AA
Sbjct: 167 AARAGPGP----------GPGPGP--GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPA 214
Query: 198 VESELNEAASRFGLGSPLPSPRASPRP-WTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPT 256
V N A+ PLP P A TP + P+P P + +AP
Sbjct: 215 VSLVNNGPAALL----PLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAA-PAPAAPAAA 269
Query: 257 PASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDP----GSP 312
P P PA R P +A+PA+ + GS P P P A P G P
Sbjct: 270 PPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP 329
Query: 313 GPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEESVAP 364
GP GA A P + A P + + + +G A + P
Sbjct: 330 GP----GAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGP 377
Score = 51.6 bits (122), Expect = 3e-06
Identities = 87/367 (23%), Positives = 122/367 (33%), Gaps = 65/367 (17%)
Query: 24 PPLGAGGLGEELDSEDAPPCCRLALG-EPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSP 82
PP G+ G P +A G EP P G A P R G P P P P P
Sbjct: 129 PPEGSAG-----SCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGP-GPGPGPGPGP 182
Query: 83 GTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGS 142
G +PA GPG G +L ++S PAAL P G+
Sbjct: 183 GPGPGKPA------GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGT 236
Query: 143 PRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESEL 202
PP G A P+P + S A+ A AA
Sbjct: 237 VIQTPPFVG-------------AAAPPAPAAPS-------PPAAPAPAAPAAAPPPPPPA 276
Query: 203 NEAASRFGLGSPLPSPRASPRPWTPE------DPWSLYGPSPGGRGPEDSWLLLSAPGPT 256
+R G P P A+P P + P+P GP + PGP
Sbjct: 277 PATLAR-PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAG---VSGQPGPG 332
Query: 257 PASPRPA--------------SPCGKRRYSSSGTPSSASPAL---SRRGSLGEEGSEPPP 299
A+ PA +P + ++SG S+A+ + + +G+L + PPP
Sbjct: 333 AAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPP 392
Query: 300 PPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAE 359
P P G+ G + + R T + +A PR +P + P +
Sbjct: 393 APGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLA-PRLPQPP----QNPTNIQ 447
Query: 360 ESVAPPG 366
PPG
Sbjct: 448 NFQLPPG 454
Score = 50.1 bits (118), Expect = 9e-06
Identities = 38/117 (32%), Positives = 47/117 (40%), Gaps = 15/117 (12%)
Query: 23 APPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPP-----PPRPGMHSPPPR 77
APP A S A P PPP AP + RPP PP PPP
Sbjct: 248 APPAPAA------PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPA 301
Query: 78 PAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISP----TPEPPAA 130
A + G+ + PA + GGP G +G G G P+ + + SP PPAA
Sbjct: 302 AAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAA 358
Score = 36.6 bits (83), Expect = 0.11
Identities = 35/126 (27%), Positives = 45/126 (35%), Gaps = 20/126 (15%)
Query: 767 ETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPF---RPPPLPASPPLE 823
+T G A PPA + PS P ++ + P PPAP RPP PA PP
Sbjct: 239 QTPPFVGAAAPPAPAA-----PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTA 293
Query: 824 GPFPSQSDVHPLPAEGYN----KVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLE 879
P P PA N P P G P + G G + P G+ E
Sbjct: 294 AP------AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG--PGAAAAAPAPGVKAE 345
Query: 880 EVSEII 885
++
Sbjct: 346 SPKRVV 351
Score = 34.7 bits (78), Expect = 0.41
Identities = 41/136 (30%), Positives = 46/136 (33%), Gaps = 22/136 (16%)
Query: 720 PPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPA 779
P P+ A E P G P P GPP RP + P PPA
Sbjct: 75 PAAPAEGAPGAAPEPPPAGRARPGGGGPQRP--GPPSPRRPLVPAGPA---------PPA 123
Query: 780 VSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLE-GPFPSQSDVHPLPAE 838
P P G GS + P + P P PA P GP + P P
Sbjct: 124 AKLRP-----PPEGSAGSCAPV--PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGP 176
Query: 839 GYNKVGPGYGPGEGAP 854
G GPG GPG G P
Sbjct: 177 G---PGPGPGPGPGKP 189
Score = 30.4 bits (67), Expect = 7.8
Identities = 37/134 (27%), Positives = 49/134 (36%), Gaps = 9/134 (6%)
Query: 255 PTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGP 314
P R A+ + SG+P+ A+ A + G G+ P PPP AR PG GP
Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAA-PEPPPAGRAR-PGGGGP 102
Query: 315 FDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEESVAP---PGGSRKE 371
PP+ P + A P E A +P A + P P G K
Sbjct: 103 --QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKP 160
Query: 372 V--AGMDYLAVPSP 383
A + A P P
Sbjct: 161 AGPAALAARAGPGP 174
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 64.7 bits (156), Expect = 4e-10
Identities = 89/377 (23%), Positives = 130/377 (34%), Gaps = 41/377 (10%)
Query: 24 PPLGAGGL------GEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPR 77
PP GGL G PP + L PPP GA PP P+ G+ +PPP+
Sbjct: 1110 PPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169
Query: 78 PAP-SPGTWESQPARSVRLGGPGGG-------AGGAGGGRVLECPSIRITSISPTPEPPA 129
AP +P P + P G GG P T+ + TP P
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229
Query: 130 ALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSW-SFFSDASDE 188
P G + PP GG +G +P+P +++ S + +
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPPKG-----APTPPAATPPSLKGGLATPPHK 1284
Query: 189 AALYAACDEVESELNEAASRFGLGSPL------PSPRASPRPWTPE---DPWSLYGPSPG 239
A A S A+ G+P PSP+ SP P+ P ++ PSP
Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344
Query: 240 GRGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPP 299
G + S GPT S + S G P+ P+ R ++ +P
Sbjct: 1345 GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS 1404
Query: 300 PPPLPLARDPGSPGPFDYVGA---------PPA---ESIPQKTRRTSSEQAVALPRSEEP 347
P +PL+ P GA PPA S+ + ++ + A P S+
Sbjct: 1405 PAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGD 1464
Query: 348 ASCNGKLPLGAEESVAP 364
+ P +E AP
Sbjct: 1465 PTLPAVTPPSPKEPPAP 1481
Score = 59.3 bits (142), Expect = 2e-08
Identities = 85/368 (23%), Positives = 122/368 (33%), Gaps = 47/368 (12%)
Query: 24 PPLGAGG------LGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPR 77
PP GG G + PP + L PP GA PP P+ G+ +PPP+
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146
Query: 78 PAP-SPGTWESQPARSVRLGGPGGG-------AGGAGGGRVLECPSIRITSISPTPEPPA 129
AP +P P + P G GG P T+ + TP P
Sbjct: 1147 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206
Query: 130 ALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGG---GAFFSPSPGSSSLSSWSFFSDAS 186
P G + PP GG +G A PSP + +
Sbjct: 1207 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTP 1266
Query: 187 DEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPE---DPWSLYGPSPGGRGP 243
A + + + ++ A + +P PSP+ P P+ P + PSP G
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTP-PSPKGGPATSPPKGAPTPPAATPPSPKG--- 1322
Query: 244 EDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPL 303
+PG P P P S GTP+ + S +G S+ P PP
Sbjct: 1323 --------SPGTPPPKGAPTPP-AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373
Query: 304 PLARDPGSPGPFDYVGAPPA----ESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAE 359
G P PP+ +IP +S + L + PA+ P+ E
Sbjct: 1374 ATPSHKGGPAM-----TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT-----PVTRE 1423
Query: 360 ESVAPPGG 367
+ P G
Sbjct: 1424 GAATPSKG 1431
Score = 51.6 bits (122), Expect = 3e-06
Identities = 91/369 (24%), Positives = 125/369 (33%), Gaps = 74/369 (20%)
Query: 49 GEPPPYGAAPI---GIPRPPP------------PRPGMHSPPPRPAPSPGTWESQPARSV 93
G P P P+ G+ PP P+ G +P P+ AP+ S P ++
Sbjct: 863 GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922
Query: 94 RLGGPGG-----GAGGAGGGRVLECPSIRITSISPTPE----PPAALEDNPDAW-GDGSP 143
P G GA PS + +P+P+ PPAA +P SP
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982
Query: 144 RDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELN 203
+ P P GG +PSP A A+
Sbjct: 983 KGAPTPPAATPPSPKGGPA-----TPSP-----------KGAPTPPAVTPP--------- 1017
Query: 204 EAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPA 263
SP SP A+P P P + PSP G P + L AP TPA+ P+
Sbjct: 1018 ---------SPKGSPAATPFPKGASTPPAATPPSPKG-SPAATPLPKGAP-TTPAATLPS 1066
Query: 264 SPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPA 323
G S G P+ PA + G + P P+P A P P P + PP
Sbjct: 1067 PKGGPATPSLKGAPT--PPAATPPSPKGGPATPSPKGAPMPPAATP--PSPKGGLATPPH 1122
Query: 324 ESIPQKTRRT--SSEQAVALPRSEEPASCNGKLPLGAEESVA--PPGGSRKEVAG----- 374
+ P T S + +A P + + P + +A PP G+ A
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 375 MDYLAVPSP 383
LA PSP
Sbjct: 1183 KGGLATPSP 1191
Score = 48.9 bits (115), Expect = 2e-05
Identities = 55/227 (24%), Positives = 74/227 (32%), Gaps = 20/227 (8%)
Query: 685 PVICKEEPLPDSSLRGFPSASATPFGTDMDF---SPPRPPYPSYPHEDPACETPYLSEGF 741
P + P + FP ++TP SP P P PA P S
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP--SPKG 1069
Query: 742 GYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSL 801
G P L PP + P + P T G PPA + P P GG +
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT------PPSPKGGLATPPHK 1123
Query: 802 GLPFSPPAPFRPPPLP----ASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQE 857
G P +P A PP P A+PP +G + + P P G P P A
Sbjct: 1124 GAPTTPAA---TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180
Query: 858 KSRGGYSSGFRDSVPIQGITLEEVSE--IIGRDLSGFPAPPGEEPPA 902
+GG ++ P + + G P P PP+
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1227
Score = 48.5 bits (114), Expect = 3e-05
Identities = 92/358 (25%), Positives = 128/358 (35%), Gaps = 57/358 (15%)
Query: 40 APPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPG 99
A P + P P GA PP P+ G +P P+ AP+P + GGP
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK----GGPA 978
Query: 100 -GGAGGAGGGRVLECPSIRITSISPTPE----PPAALEDNPDAWGDGSPRDYPPPEGFGG 154
GA PS + +P+P+ PPA +P GSP P P+
Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP----KGSPAATPFPK---- 1030
Query: 155 YREAGGQGGGAFFSPSP-GSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGS 213
G A PSP GS + + + + A L + + + A +
Sbjct: 1031 ----GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
Query: 214 PLPSPRASPRPWTPED---PWSLYGPSP-GGRGPEDSWLLLSAPGPTPASPRP--ASPCG 267
P PSP+ P +P+ P + PSP GG + P TP SP+ A+P
Sbjct: 1087 P-PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP 1145
Query: 268 KRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIP 327
K + TP++ P S +G L PPP P P P + P + P
Sbjct: 1146 K---GAPTTPAATPP--SPKGGLA-----TPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 328 QKTRRT--SSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSP 383
T S + +A P S G A +P GG LA PSP
Sbjct: 1196 TTPAATPPSPKGGLATP------SPKGAPTTPAATPPSPKGG----------LATPSP 1237
Score = 46.6 bits (109), Expect = 1e-04
Identities = 63/241 (26%), Positives = 80/241 (33%), Gaps = 46/241 (19%)
Query: 674 KRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP------PYPSYPH 727
K +PT S LP KE P + + P+ S T + P P P P
Sbjct: 883 KETPTPSVVNLP-FPKEGPATPAPKQA-PALSMTSSSPKKARATPAPKGIPASPSPKGAP 940
Query: 728 EDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPF 787
PA P G P P PP + P + P T G PPA +
Sbjct: 941 TPPAATPPSPKGGPATPSPKWAPT--PPAATPPSPKGGPATPSPKGAPTPPAAT------ 992
Query: 788 PSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGYNKVGPGY 847
P P GG + G P +PPA PP P P PFP + P K P
Sbjct: 993 PPSPKGGPATPSPKGAP-TPPAV--TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049
Query: 848 GP-GEGAPEQEKS-----RGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEPP 901
P +GAP + +GG ++ L G P PP PP
Sbjct: 1050 TPLPKGAPTTPAATLPSPKGGPAT---------------------PSLKGAPTPPAATPP 1088
Query: 902 A 902
+
Sbjct: 1089 S 1089
Score = 42.7 bits (99), Expect = 0.002
Identities = 67/249 (26%), Positives = 88/249 (35%), Gaps = 41/249 (16%)
Query: 689 KEEPLPDSSLRGFPS---ASATPFGTDMD--FSPPRPP--YPSYPHED----PACETPYL 737
K P P ++ P A+ +P G M +PP P + PH+ PA P
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
Query: 738 SEGFGYGMPPLYPQT--GPPPSYRPGLRMFPETRG--TTGCAQPPA------------VS 781
G P P T PPS + GL P +G TT A PP+
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPKGGLAT-PPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 782 FLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGYN 841
P P P GG + G P +P A PP P L P P + P
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAA---TPPSPKG-GLATPSPKGAPTTPAATPPSP 1251
Query: 842 KVGPGYGPGEGAPEQEKS-----RGGYSSGFRDSVPIQGITLEEVSEIIGRDLS---GFP 893
K GP P +GAP + +GG ++ P + + S G S G P
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAV-VTPPSPKGGPATSPPKGAP 1310
Query: 894 APPGEEPPA 902
PP PP+
Sbjct: 1311 TPPAATPPS 1319
Score = 42.0 bits (97), Expect = 0.003
Identities = 94/399 (23%), Positives = 131/399 (32%), Gaps = 60/399 (15%)
Query: 18 GEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGA---------APIGIPRPPPPR 68
G +PP GA PP + + G PPP GA +P G P P
Sbjct: 1299 GGPATSPPKGA-----PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
Query: 69 PGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPP 128
P P P+ G S + GGP G + P TS + P P
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHK-GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
Query: 129 AALEDNP--------DAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS 180
P + GD +P P + +GG A S S G +L + +
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPS-SKGDPTLPAVT 1471
Query: 181 FFSDASDEAALYAACDEVESELNEAASRFGLGSP-LPSPRASPRPWTPEDPWSLYGP--- 236
S A A S A+ +G+P LP+ S P P S P
Sbjct: 1472 PPSPKEPPAPKQVATSS--SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529
Query: 237 --------SPGGRGPEDSWL--LLSAPGP--TPASPRP----ASPCGKRRYSSSG-TPSS 279
+P P+++ + ++ P P TPA P P A+P K S TPS+
Sbjct: 1530 TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPST 1589
Query: 280 ASPALSRRGSL---------GEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKT 330
A S + L +E PP P + P +P P +PP K
Sbjct: 1590 YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKD 1649
Query: 331 RRTSSEQAVALPRSEEPASCNG----KLPLGAEESVAPP 365
TS + P + G K P +E + P
Sbjct: 1650 SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688
Score = 40.8 bits (94), Expect = 0.006
Identities = 49/177 (27%), Positives = 63/177 (35%), Gaps = 18/177 (10%)
Query: 694 PDSSLRGFPSASATPFGTDMDFSPPRP------PYPSYPHEDPACETPYLSEGFGYGMPP 747
P S G + S T +PP P P P PA P S G PP
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP--SPKGGPATPP 1259
Query: 748 LYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSP 807
PP + P L+ T G P V+ P P GG +S G P +P
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVT------PPSPKGGPATSPPKGAP-TP 1312
Query: 808 PAPFRPPP--LPASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGG 862
PA P P P +PP +G P+ V P +G + +G P S+ G
Sbjct: 1313 PAATPPSPKGSPGTPPPKGA-PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368
Score = 35.8 bits (81), Expect = 0.18
Identities = 70/309 (22%), Positives = 101/309 (32%), Gaps = 45/309 (14%)
Query: 48 LGEPPPYGAAPIGIPRPPP---PRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGG 104
L + P AP PP P P P P +P T S+ A S P G
Sbjct: 1534 LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA 1593
Query: 105 AGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGG 164
+L P++ S P PPA +P+ G +P P
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK-GPATPAPKGTPT-------------- 1638
Query: 165 AFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRP 224
SP SSL S S AS + A + L L L +P P
Sbjct: 1639 ---SPPVTPSSLKD-SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP 1694
Query: 225 WTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPAL 284
+P +GP+ ++P P P P++ G + S+ P+ P
Sbjct: 1695 II---------TAPTRKGPQTKKSSATSP---PICPDPSAKNGSKGPLSTVAPAPLLPVQ 1742
Query: 285 --SRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQA---- 338
S + + G++ S P P P +P + A E + K S A
Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPPESKASTP-----LTAAAFEKVLPKPESASVSAAPSPP 1797
Query: 339 VALPRSEEP 347
V+LP + P
Sbjct: 1798 VSLPLAPSP 1806
Score = 35.4 bits (80), Expect = 0.24
Identities = 51/212 (24%), Positives = 74/212 (34%), Gaps = 15/212 (7%)
Query: 212 GSPLPSPRASPRPWTPEDPWSLYGPS-PGGRGPEDSWLLLSAPGPTPASPRPASPCGKRR 270
G LP P+ +P P P+ GP+ P + + S+P A+P P
Sbjct: 877 GVTLP-PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS 935
Query: 271 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAP-PAESIPQK 329
+ TP +A+P + G P PP G P GAP P + P
Sbjct: 936 PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS 995
Query: 330 TR---RTSSEQAVALPRSEEPASCNGK-----LPLGAE--ESVAPPGGSRKEVA-GMDYL 378
+ T S + P + P S G P GA + PP A +
Sbjct: 996 PKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055
Query: 379 AVPSPLAWSKARIGG-HSPIFRTSALPPLDWP 409
A +P A + GG +P + + PP P
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATP 1087
Score = 33.9 bits (76), Expect = 0.70
Identities = 44/156 (28%), Positives = 53/156 (33%), Gaps = 20/156 (12%)
Query: 692 PLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHED-PACETPYLSEGFGYGMP---P 747
P S +G P+ ++ G P PP + H+ PA P G P P
Sbjct: 1350 PATTPSSKGGPTTPSSKEG-------PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
Query: 748 LYPQTGP-PPSYRPGLRMFPETRGTT--GCAQPPAV---SFLPRPFPSDPYGGRGSSFSL 801
P P P P + E T G PPAV S P S P GG + S
Sbjct: 1403 TSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK 1462
Query: 802 GLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPA 837
G P P PP P PP + S PA
Sbjct: 1463 G---DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495
Score = 33.5 bits (75), Expect = 0.92
Identities = 36/137 (26%), Positives = 41/137 (29%), Gaps = 10/137 (7%)
Query: 702 PSASATPFGTDMDFSPPRPPY--PSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYR 759
PS P T P PP P P PA +P G P T P P
Sbjct: 971 PSPKGGP-ATPSPKGAPTPPAATPPSPKGGPATPSPK-------GAPTPPAVTPPSPKGS 1022
Query: 760 PGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPAS 819
P FP+ T A PP+ P P + +L P PA P
Sbjct: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082
Query: 820 PPLEGPFPSQSDVHPLP 836
P P P P P
Sbjct: 1083 PAATPPSPKGGPATPSP 1099
Score = 30.4 bits (67), Expect = 7.8
Identities = 47/171 (27%), Positives = 58/171 (33%), Gaps = 25/171 (14%)
Query: 716 SPPRP---PYPSYPH--EDPACETPYLSEGFGYGMPPLYPQTGP---PPSYR-------- 759
+PP P P S P P TP +G PP T P PPS +
Sbjct: 1293 TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPAT 1352
Query: 760 -PGLRMFPET----RGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPA-PFRP 813
P + P T G T A P+ P P P G G P SP P P
Sbjct: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
Query: 814 PPLPASPPLE--GPFPSQSDVHPLPAEGYN-KVGPGYGPGEGAPEQEKSRG 861
PA+P PS+ D+ P + K P +G P S+G
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 63.9 bits (154), Expect = 6e-10
Identities = 113/435 (25%), Positives = 138/435 (31%), Gaps = 80/435 (18%)
Query: 18 GEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGA-------APIGIPRPPPPRPG 70
G+ E P G G ++ P A GEP GA P G PP P
Sbjct: 800 GDRGEPGPPGPAGFAGPPGADGQPG----AKGEPGDAGAKGDAGPPGPAGPAGPPGPIGN 855
Query: 71 MHSPPPRPA---PSPGTWESQPARSVRLG--GPGGGAG-----------GAGGGRVLECP 114
+ +P + A P P + R+G GP G AG G G R P
Sbjct: 856 VGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGP 915
Query: 115 SIRITSISPTPEP-PAALEDNPDAWGDGSPRDYPPPEGFGGYREA---GGQGGGAFFSPS 170
+ R + P P PA + +P A G P P+G G R GQ G F
Sbjct: 916 AGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL 975
Query: 171 PGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDP 230
PG S S AS E GL P P S R P
Sbjct: 976 PGPSGEPGKQGPSGASGERGPPGPMGPP-----------GLAGP---PGESGREGAPGAE 1021
Query: 231 WSL-YGPSPGGRGPEDSWLLLSAPGP--TPASPRPASPCGKR----RYSSSGTPSSASPA 283
S SPG +G PG P +P P P GK +G P
Sbjct: 1022 GSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPV 1081
Query: 284 LSR--------RGSLGEEGSE----------------PPPPPPLPLARDP-GSPGPFDYV 318
+R RG GE G + PP PP P + P G+ GP
Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR 1141
Query: 319 GAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYL 378
G P + P K + P G P+G PPG AG D+
Sbjct: 1142 GPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAG--PVGPPGPPGPPGPPGPPSAGFDFS 1199
Query: 379 AVPSPLAWSKARIGG 393
+P P KA GG
Sbjct: 1200 FLPQP-PQEKAHDGG 1213
Score = 58.5 bits (140), Expect = 3e-08
Identities = 90/324 (27%), Positives = 107/324 (33%), Gaps = 59/324 (18%)
Query: 59 IGIPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPG-GGAGGAGGGRVLECPSIR 117
I +P P P P P AP P ++ P G PG GA G G R
Sbjct: 175 ISVPGPMGPSGPRGLPGPPGAPGPQGFQGPP------GEPGEPGASGPMGPR-------- 220
Query: 118 ITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLS 177
P PP D+ +A G P + PP G G R G G PG
Sbjct: 221 -----GPPGPPGKNGDDGEAGKPGRPGERGPP-GPQGARGLPGTAG------LPGMKGHR 268
Query: 178 SWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPS 237
+S A +A E S A G P P RP P GP+
Sbjct: 269 GFSGLDGAKGDAGPAGPKGEPGSPGENGAP--GQMGPRGLPGERGRPGAP-------GPA 319
Query: 238 PGGRGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEG--S 295
G RG + + PGPT + P P + G A P RGS G +G
Sbjct: 320 -GARGNDGATGAAGPPGPTGPAGPPGFP------GAVGAKGEAGPQ-GPRGSEGPQGVRG 371
Query: 296 EPPPPPPLPLARDPGSPGPFDYVGAPPAESIP--------QKTRRTSSEQAVALP----- 342
EP PP P A G+PG GA A P R S Q P
Sbjct: 372 EPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKG 431
Query: 343 RSEEPASCNGKLPLGAEESVAPPG 366
S EP + K GA+ P G
Sbjct: 432 NSGEPGAPGSKGDTGAKGEPGPVG 455
Score = 54.3 bits (129), Expect = 5e-07
Identities = 86/322 (26%), Positives = 108/322 (33%), Gaps = 54/322 (16%)
Query: 16 VFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGA----------APIGIPRPP 65
V GE P GA G D P + A G P GA P G PP
Sbjct: 369 VRGEPGPPGPAGAAGPAGN-PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPP 427
Query: 66 PPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTP 125
P+ G P P T V + GP G AG G P
Sbjct: 428 GPK-GNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPG---------- 476
Query: 126 EPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDA 185
P L P G R +P +G G + G+ G SPG + +
Sbjct: 477 --PTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERG------SPGPAGPKGSPGEAGR 528
Query: 186 SDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPED 245
EA L A S GSP P + P +D GP PG G
Sbjct: 529 PGEAGLPGAKGLTGSP----------GSPGPDGKTGPPGPAGQD--GRPGP-PGPPGARG 575
Query: 246 SWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPL 305
++ PGP A+ P G+R G P + PA G GE G++ PP P P
Sbjct: 576 QAGVMGFPGPKGAAGEPGK-AGER--GVPGPPGAVGPA----GKDGEAGAQGPPGPAGP- 627
Query: 306 ARDPGSPGPFDYVGAPPAESIP 327
A + G GP G+P + +P
Sbjct: 628 AGERGEQGP---AGSPGFQGLP 646
Score = 52.4 bits (124), Expect = 2e-06
Identities = 87/334 (26%), Positives = 111/334 (33%), Gaps = 43/334 (12%)
Query: 56 AAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPG-GGAGGAGGGRVLECP 114
A P G P+ P PG + P + P P R G PG GA G G P
Sbjct: 280 AGPAG-PKGEPGSPGENGAPGQMGP-----RGLPGERGRPGAPGPAGARGNDGATGAAGP 333
Query: 115 SIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSS 174
P P P A+ +A G PR P+G G G G A + +PG+
Sbjct: 334 PGPTGPAGP-PGFPGAVGAKGEA-GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGAD 391
Query: 175 SLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSP-LPSPRASPRPWTPEDPWSL 233
+ A A G+P P R P P P
Sbjct: 392 GQPGAKGANGAPGIA----------------------GAPGFPGARGPSGPQGPGGPPGP 429
Query: 234 YGPS--PGGRGPEDSWLLLSAPGPTPAS--PRPASPCGKRRYSSSGTPSSASPALSRRG- 288
G S PG G + PGP P PA GKR P+ RG
Sbjct: 430 KGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGG 489
Query: 289 --SLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEE 346
S G G++ P P A + GSPGP G+P P + ++ P S
Sbjct: 490 PGSRGFPGADGVAGPKGP-AGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG 548
Query: 347 PASCNGKL-PLGAEESVAPPG--GSRKEVAGMDY 377
P G P G + PPG G+R + M +
Sbjct: 549 PDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGF 582
Score = 50.4 bits (119), Expect = 7e-06
Identities = 79/336 (23%), Positives = 98/336 (29%), Gaps = 43/336 (12%)
Query: 47 ALGEPPPYG-AAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGA 105
A G P P G A P G P + PR + P +P GP G AG A
Sbjct: 330 AAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPP----GPAGAAGPA 385
Query: 106 GGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGA 165
G P + + +P G P P P+G G A G G
Sbjct: 386 GNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDT 445
Query: 166 FFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPW 225
PG + E R G P P+ P
Sbjct: 446 GAKGEPGPVGVQG-------------------PPGPAGEEGKRGARGEPGPTGLPGP--- 483
Query: 226 TPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSAS--PA 283
P GP G D P SP PA P G +G P A A
Sbjct: 484 ----PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSP--GEAGRPGEAGLPGA 537
Query: 284 LSRRGSLGEEGSEPPPPPPLPLARD--PGSPGP------FDYVGAPPAESIPQKTRRTSS 335
GS G G + PP P +D PG PGP +G P + + +
Sbjct: 538 KGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGE 597
Query: 336 EQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKE 371
P + PA +G+ A P G R E
Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGE 633
Score = 47.4 bits (111), Expect = 6e-05
Identities = 85/334 (25%), Positives = 104/334 (31%), Gaps = 69/334 (20%)
Query: 49 GEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAP--SPGTWESQPARSVRLGGPG--GGAGG 104
G+ P GA+ P P PG+ PP +PG E P R G G G G
Sbjct: 983 GKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGA-EGSPGRDGSPGAKGDRGETGP 1041
Query: 105 AGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGG 164
AG P +P P PA + G P P G G G G
Sbjct: 1042 AGPPGAPGAPG------APGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095
Query: 165 AFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRP 224
+ G + FS GL P P P SP
Sbjct: 1096 KGETGEQGDRGIKGHRGFS--------------------------GLQGP-PGPPGSPGE 1128
Query: 225 WTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPAS--PRPASPCGKRRYSSSGTPSSASP 282
+ P GP+ G RGP S APG + P P P G R
Sbjct: 1129 ---QGPSGASGPA-GPRGPPGS---AGAPGKDGLNGLPGPIGPPGPR------------- 1168
Query: 283 ALSRRGSLGEEGSEPPPPPPLPLARDPGSPG---PFDYVGAPPAESIPQKTRRTSSEQAV 339
R G G G PP PP P PG P F ++ PP E R ++ A
Sbjct: 1169 --GRTGDAGPVGPPGPPGPPGP----PGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDAN 1222
Query: 340 ALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVA 373
+ + K E++ P GSRK A
Sbjct: 1223 VVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPA 1256
Score = 38.5 bits (88), Expect = 0.028
Identities = 48/176 (27%), Positives = 67/176 (38%), Gaps = 30/176 (17%)
Query: 702 PSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMP-PLYP--QTGPP--- 755
P + P G D + PP P+ P + + P S GF G+P P P + G P
Sbjct: 603 PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF-QGLPGPAGPPGEAGKPGEQ 661
Query: 756 ----------PSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPF 805
PS G R FP RG G PP P+ P G G+ + G
Sbjct: 662 GVPGDLGAPGPSGARGERGFPGERGVQG---PPG--------PAGPRGANGAPGNDGAKG 710
Query: 806 SPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRG 861
AP P +P L+G P + LP ++ G +G+P ++ RG
Sbjct: 711 DAGAP-GAPGSQGAPGLQG-MPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG 764
Score = 38.5 bits (88), Expect = 0.028
Identities = 61/231 (26%), Positives = 77/231 (33%), Gaps = 47/231 (20%)
Query: 702 PSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFG-----------YGMPPLYP 750
P P G + PP PP P+ P + P + G G+P
Sbjct: 909 PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRG 968
Query: 751 QTG----PPPSYRPGLRMFPE----TRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLG 802
+ G P PS PG + P RG G PP ++ P S G G+ S G
Sbjct: 969 ERGFPGLPGPSGEPG-KQGPSGASGERGPPGPMGPPGLA--GPPGESGREGAPGAEGSPG 1025
Query: 803 LPFSPPA--------PFRPPPLPASPPLEGPF----PSQSDVHPLPAEGYNKVGPGYGPG 850
SP A P PP P +P GP S PA VGP G
Sbjct: 1026 RDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARG 1085
Query: 851 EGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEPP 901
P+ + G +G + I+G R SG PPG PP
Sbjct: 1086 PAGPQGPRGDKG-ETGEQGDRGIKG----------HRGFSGLQGPPG--PP 1123
Score = 38.1 bits (87), Expect = 0.037
Identities = 68/269 (25%), Positives = 86/269 (31%), Gaps = 40/269 (14%)
Query: 113 CPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPG 172
CP S SPT + +E G PR P G G G G PG
Sbjct: 92 CPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPG 151
Query: 173 SSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSP--LPSPRASPRPWTPEDP 230
L + L DE + G P LP P +P P + P
Sbjct: 152 PPGLG-------GNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGP 204
Query: 231 WSLYGPSPGGRGPEDSWLLLSAPGP-----------TPASPRPASPCGKRRYSSSGTPSS 279
G PG GP PGP P P P G + + G P +
Sbjct: 205 PGEPG-EPGASGPMGP---RGPPGPPGKNGDDGEAGKPGRPGERGPPGPQ--GARGLPGT 258
Query: 280 AS-PAL-SRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQ 337
A P + RG G +G++ P P +PGSPG G +P + R
Sbjct: 259 AGLPGMKGHRGFSGLDGAKGDAGPAGPKG-EPGSPGENGAPGQMGPRGLPGERGR----- 312
Query: 338 AVALPRSEEPASCNGKLPLGAEESVAPPG 366
P + PA G GA + PPG
Sbjct: 313 ----PGAPGPAGARGN--DGATGAAGPPG 335
Score = 37.7 bits (86), Expect = 0.049
Identities = 89/382 (23%), Positives = 111/382 (29%), Gaps = 81/382 (21%)
Query: 49 GEPPPYGAAPIGIP----RPP----PPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGG 100
G P P G P G P RP P G+ P P P T PA GP G
Sbjct: 512 GSPGPAG--PKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPG 569
Query: 101 GAGGAGGGRVLECPSIRITSISP-------TPEPPAAL-----------EDNPDAWGDGS 142
G G V+ P + + P P PP A+ + P G
Sbjct: 570 PPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAG 629
Query: 143 PRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDE--VES 200
R P G G++ G G + PG + S E V+
Sbjct: 630 ERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQG 689
Query: 201 ELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPS----PGGRGPEDSWLLLSAPGPT 256
A R G+P + A P P S P PG RG PGP
Sbjct: 690 PPGPAGPRGANGAP-GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAA------GLPGPK 742
Query: 257 ----PASPR-------------------PASPCGKRRYSSSGTPSSASPALSRRGSLGEE 293
A P+ P P G PS + RG+ G+
Sbjct: 743 GDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDR 802
Query: 294 GSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGK 353
G PP P G GP G P A+ P ++ P PA G
Sbjct: 803 GEPGPPGP-------AGFAGPPGADGQPGAKGEPGD---AGAKGDAGPPGPAGPAGPPGP 852
Query: 354 L-------PLGAEESVAPPGGS 368
+ GA S PPG +
Sbjct: 853 IGNVGAPGAKGARGSAGPPGAT 874
Score = 34.7 bits (78), Expect = 0.41
Identities = 34/103 (33%), Positives = 37/103 (35%), Gaps = 17/103 (16%)
Query: 744 GMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPR-------PFPSDPYGGRG 796
G L GPP S PG + G G PP + P P P P G RG
Sbjct: 1112 GFSGLQGPPGPPGS--PGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRG 1169
Query: 797 SSFSLGLPFSPPAPFRPPPLPASPPLEG------PFPSQSDVH 833
+ G P PP P PP P PP G P P Q H
Sbjct: 1170 RTGDAG-PVGPPGP-PGPPGPPGPPSAGFDFSFLPQPPQEKAH 1210
Score = 32.3 bits (72), Expect = 2.0
Identities = 33/126 (26%), Positives = 42/126 (33%), Gaps = 16/126 (12%)
Query: 747 PLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLP----------RPFPSDPYGGRG 796
P P+ P + RPG P +G TG P RP P P G RG
Sbjct: 516 PAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG 575
Query: 797 SSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQ 856
+ +G P P P + GP V P +G + G PG P
Sbjct: 576 QAGVMGFP-GPKGAAGEPGKAGERGVPGP---PGAVGPAGKDG--EAGAQGPPGPAGPAG 629
Query: 857 EKSRGG 862
E+ G
Sbjct: 630 ERGEQG 635
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 63.9 bits (154), Expect = 6e-10
Identities = 114/442 (25%), Positives = 156/442 (35%), Gaps = 67/442 (15%)
Query: 41 PPCCRLALGEPPPYGAAPIGIPR----PPPPRPGMHSPPPR--------PAPSPGTWESQ 88
PP ++ PPP + P P PP + +PPP+ P +P + +
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
Query: 89 PARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPP 148
P S L P A A +L+ P SP P PP +P A SP PP
Sbjct: 640 PPLS-PLATPSPQAPNALAVHLLQAP------FSPPPSPPVQAPFSPPASPPVSPSATPP 692
Query: 149 PEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASR 208
+ Q PSP +S S S + +A A ++ + AS
Sbjct: 693 SQAPPSLAAPPLQ-----VPPSPPASPPMSPS--ATPPPQAPPPLAAPPLQVPPSPPASP 745
Query: 209 FGLGSPLPSPR-----ASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPR-P 262
S P PR A+P P P + SP + P + L+ P P A P P
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP-PLQALPSPP 804
Query: 263 ASPCGKRRYSSSGT---------PSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPG 313
AS G+ +S S + P A P L+ L + PP P L R P +PG
Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLA--APLLQVPPSPPASPTLQAPRRPPTPG 862
Query: 314 PFDYVGAP-------PAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPG 366
P V P P P +S+ L A+ + G + P G
Sbjct: 863 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS--GPEG 920
Query: 367 GSRKEVAGMDYLAVPSPLAWSKARIGGHSPI-FRTSALPPLDWPLPSQYEQLELRIEVQP 425
G+ LA P AWS+ G P+ FR + PL WP + + +
Sbjct: 921 GAAASPPPDAELAACHPAAWSR---GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI-- 975
Query: 426 RAHHRAHYETEGSRGAVKAAPG 447
YETEG A APG
Sbjct: 976 -------YETEGPESAT-PAPG 989
Score = 57.8 bits (138), Expect = 5e-08
Identities = 96/363 (26%), Positives = 125/363 (34%), Gaps = 56/363 (15%)
Query: 51 PPPYGAAPIGIPRPPPPRPGM--------HSPPPRPAPSPGTWESQPARSVRLGGPGGGA 102
PP A P+ +P PP P M +PPP AP S PA P
Sbjct: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA------SPPMSP 749
Query: 103 GGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQG 162
RV P + + P PPA+L +P A PPP+ Q
Sbjct: 750 SATPPPRV--PPLLAAPPLQVPPSPPASLPMSPLA--------KPPPQAPPALATPPLQA 799
Query: 163 GGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPL----PSP 218
PSP +S F AS + A + L +PL PSP
Sbjct: 800 -----LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV--------LAAPLLQVPPSP 846
Query: 219 RASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPR-PASPCGKRRYSSSGTP 277
ASP P P GP GP L APGP P R P+S + +
Sbjct: 847 PASPTLQAPRRP-PTPGPDTSVSGPR--LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 903
Query: 278 SSASPALSRRGSLGEEGSEPPPPPP-------LPLARDPGSPGPFDYVGAPPAE-SIPQK 329
++++P R G EG PPP P A G P + GAP A P
Sbjct: 904 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 963
Query: 330 TRRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKA 389
T S++ + +E P S P + +P K AG A S + +A
Sbjct: 964 TGPGSADGLCTIYETEGPESAT-PAPGALDPGPSPGTSGGKAAAGAG--AGASSRSPKQA 1020
Query: 390 RIG 392
R+G
Sbjct: 1021 RLG 1023
Score = 54.3 bits (129), Expect = 5e-07
Identities = 70/248 (28%), Positives = 89/248 (35%), Gaps = 59/248 (23%)
Query: 50 EPPPYGAAPI-GIPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGG 108
+ PP AAP+ +P PP P + +P P P P T S P ++ L PG
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL-APG--------- 879
Query: 109 RVLECPSIRITSISPTPEP---PAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGA 165
P P P P++ PD G S PE GY G GGA
Sbjct: 880 --------------PPPPPSRSPSSTLSGPDLAGHSSSAT-STPEELRGY--DSGPEGGA 922
Query: 166 FFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEA---ASRFGLGSPLPSPRASP 222
SP P A AAC A A R G+PLP P A+
Sbjct: 923 AASPPPD-----------------AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT- 964
Query: 223 RPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASP 282
P + + ++Y GPE + APG P P + GK + SS SP
Sbjct: 965 GPGSADGLCTIYET----EGPESA---TPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 1017
Query: 283 ALSRRGSL 290
+R G L
Sbjct: 1018 KQARLGEL 1025
Score = 52.8 bits (125), Expect = 1e-06
Identities = 99/361 (27%), Positives = 128/361 (35%), Gaps = 60/361 (16%)
Query: 58 PIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIR 117
P G PRPPPP + R + G +P + R GG GG R S
Sbjct: 29 PPGSPRPPPP---VTPAALRVLGAAGAVGRKPL-AERAGGIGGATIPESAPRAGPTRSAG 84
Query: 118 ITSISPTPEPPA---------ALEDNP---DAWGDGSPRDYPPPEGFGGYR----EAGGQ 161
+S +P PPA A +P + G S P P G G R E +
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
Query: 162 GGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRAS 221
G + +P S+LS+ + D + A+ +G P P+P A
Sbjct: 145 GKA---TEAPKRSALSAGA----RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197
Query: 222 PRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCG------KRRYSSSG 275
PRP P+ G R S S P+PA+ R S G R SSS
Sbjct: 198 PRP-----------PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
Query: 276 TPSSASPALSRRGSLGEEGSEPPPPPPLP---LARDPGSPGPFDYVGAP---PAESIPQK 329
TP S SPA S + G + P P P A P P AP P S P
Sbjct: 247 TPLS-SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
Query: 330 TRRTSSEQAVALPRSEE-----PASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPL 384
T S +A +P + PA+ PL +APP S A +PSP
Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS----APPSLQTLPSPP 361
Query: 385 A 385
A
Sbjct: 362 A 362
Score = 50.8 bits (120), Expect = 6e-06
Identities = 55/166 (33%), Positives = 65/166 (39%), Gaps = 35/166 (21%)
Query: 702 PSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPG 761
PS+ ATP PP+ P PA +P L G PPL P PPP P
Sbjct: 584 PSSIATP--------PPQAP--------PALASPPLQ---GLPSPPLSPLATPPPQAPPX 624
Query: 762 LRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPP------APFRPPP 815
L + P + A PP +S L P P P + L PFSPP APF PP
Sbjct: 625 LALPPLQAPPSPPASPP-LSPLATPSPQAP--NALAVHLLQAPFSPPPSPPVQAPFSPPA 681
Query: 816 LP-----ASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQ 856
P A+PP + P PS + PL P P P Q
Sbjct: 682 SPPVSPSATPPSQAP-PSLA-APPLQVPPSPPASPPMSPSATPPPQ 725
Score = 48.9 bits (115), Expect = 2e-05
Identities = 96/383 (25%), Positives = 127/383 (33%), Gaps = 98/383 (25%)
Query: 41 PPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGG 100
PP L PPP A + P PP PAP P
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTP------HLETPPCPAPCP------------------ 568
Query: 101 GAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGG 160
L+ P +T +P PE P+++ PPP+
Sbjct: 569 ----------LQAPPSPLT--TPPPETPSSIAT-------------PPPQAPPALASPPL 603
Query: 161 QGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRA 220
QG PSP S L++ +A A +++ PSP A
Sbjct: 604 QG-----LPSPPLSPLAT------PPPQAPPXLALPPLQAP--------------PSPPA 638
Query: 221 SPRPWTPEDPWSLYGPSPGGRGPEDSWLLLS--APGPTPASPRPASPCGKRRYSSSGTPS 278
SP P +P L PSP LL + +P P+P P SP S S TP
Sbjct: 639 SP-PLSP-----LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 692
Query: 279 SASPALSRRGSLGEEGSEPPPPP------PLPLARDPGSPGPFDYVGAPPAE--SIPQKT 330
S +P L S P PP P P A P + P +PPA P T
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT 752
Query: 331 RRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKAR 390
+A P + P S LP+ PP + +A A+PSP A
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPASLPM--SPLAKPPPQAPPALATPPLQALPSP----PAS 806
Query: 391 IGGHSPIFRTSALP--PLDWPLP 411
G +P +++LP PL P P
Sbjct: 807 FPGQAPFSPSASLPMSPLATPPP 829
Score = 42.0 bits (97), Expect = 0.003
Identities = 77/287 (26%), Positives = 97/287 (33%), Gaps = 52/287 (18%)
Query: 105 AGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPE-------GFGGY-- 155
A G P+ R + TP PP GSPR PP G G
Sbjct: 8 AKAGAAARTPAARAPGLL-TPRPP------------GSPRPPPPVTPAALRVLGAAGAVG 54
Query: 156 -----REAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFG 210
AGG GG +P + S A AS G
Sbjct: 55 RKPLAERAGGIGGATIPESAPRAGPTRS--------------AGTSSRNPASRPPASGRG 100
Query: 211 LGSPLPSPRASPRPWT-PEDPWSLYGPSP-GGRGPEDSWLLLSAPGPTPASP-RPASPCG 267
+P P+ SP P + P P P G +G S A G +P R A G
Sbjct: 101 ERAP-PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG 159
Query: 268 KRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARD-PGSPGPFDYVGA----PP 322
RR +S TP + SPA++RR G+E P P P AR P + GP V +
Sbjct: 160 ARRDTSGPTPGTPSPAMARRSRAA--GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHST 217
Query: 323 AESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSR 369
E P RR S+ + P S +S L A + G R
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Score = 40.0 bits (92), Expect = 0.010
Identities = 48/173 (27%), Positives = 58/173 (33%), Gaps = 20/173 (11%)
Query: 693 LPDSSLRGFPSASATPFGTDMDFSPPR---PPY---PSYPHEDPACE--TPYLSEGFGYG 744
L L+G PS +P T +PP PP PS P P TP
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657
Query: 745 MPPLYPQTGPPPS------YRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSS 798
+ L PPPS + P T PP+++ P P P S
Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
Query: 799 FSLGLPFSPPAPFRPPPL------PASPPLEGPFPSQSDVHPLPAEGYNKVGP 845
S P P P PPL PASPP+ V PL A +V P
Sbjct: 718 PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
Score = 39.7 bits (91), Expect = 0.013
Identities = 40/140 (28%), Positives = 53/140 (37%), Gaps = 30/140 (21%)
Query: 703 SASATPF------GTDMDFSPPRPPYPSYPHED--PACETPYLSEGFGYGMPPLYPQTGP 754
S+SATP G +P P +PS P A P ++ P L P +
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
Query: 755 PPSYRPGLRMFPETRGTTGCAQPP---AVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPF 811
P + P GT PP A + LP P P + LP +PP+P
Sbjct: 303 PLAT-------PSPSGTKARPVPPPDNAATPLPATLPPSP------PLATPLPLAPPSPS 349
Query: 812 RPPPL------PASPPLEGP 825
PP L PA+PP + P
Sbjct: 350 APPSLQTLPSPPATPPSQAP 369
Score = 38.1 bits (87), Expect = 0.037
Identities = 46/165 (27%), Positives = 57/165 (34%), Gaps = 9/165 (5%)
Query: 692 PLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLY-- 749
P P +SL P A P +PP PS P P + P+ S M PL
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG-QAPF-SPSASLPMSPLATP 827
Query: 750 PQTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPA 809
P PP P L++ P + P P P P G + +L P PP
Sbjct: 828 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRP---PTPGPDTSVSGPRLTLALA-PGPPPP 883
Query: 810 PFRPPPLPASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAP 854
P R P S P S + P GY+ GP G P
Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS-GPEGGAAASPP 927
Score = 37.4 bits (85), Expect = 0.063
Identities = 43/140 (30%), Positives = 54/140 (38%), Gaps = 20/140 (14%)
Query: 692 PLPDSSLRGFPSASATPFGTDMDFSPPR---PPYPSYPHEDPACETPYLSEGFGYGMPPL 748
P P +S PSA+ P +PP P P+ P P+ P +PPL
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR-------VPPL 760
Query: 749 Y--PQTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLP-RPFPSDPYGGRGSSFSLGLPF 805
P PPS L M P + PPA++ P + PS P +SF PF
Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQA--PPALATPPLQALPSPP-----ASFPGQAPF 813
Query: 806 SPPAPFRPPPLPASPPLEGP 825
SP A PL PP P
Sbjct: 814 SPSASLPMSPLATPPPQAPP 833
Score = 36.6 bits (83), Expect = 0.11
Identities = 41/140 (29%), Positives = 49/140 (35%), Gaps = 21/140 (15%)
Query: 715 FSPPRPPYPSYPHEDPACETPYLSEG------FGYGMPPLYPQTGPPPSYRPGLRMFPET 768
FSPP P S P+ P L+ PP+ P PPP P L P
Sbjct: 677 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736
Query: 769 RGTTGCAQPP-AVSFLPRPF-------------PSDPYGGRGSSFSLGLPFSPPAPFRPP 814
+ A PP + S P P PS P S + P +PPA P
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA-LATP 795
Query: 815 PLPASPPLEGPFPSQSDVHP 834
PL A P FP Q+ P
Sbjct: 796 PLQALPSPPASFPGQAPFSP 815
Score = 35.0 bits (79), Expect = 0.31
Identities = 57/258 (22%), Positives = 77/258 (29%), Gaps = 60/258 (23%)
Query: 676 SPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRPPY---------PSYP 726
SP SF LP S L P + + PP PP P P
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861
Query: 727 HEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMF-PETRGTTGCAQPPAVSFLPR 785
D + P L+ G PP PPS P + P+ G + A R
Sbjct: 862 GPDTSVSGPRLTLALAPGPPP-------PPSRSPSSTLSGPDLAGHSSSATSTPEEL--R 912
Query: 786 PFPSDPYGG--------------------RGSSFSLGLPFSPPAPFRPPPLPASPPLEG- 824
+ S P GG RG + L +P AP PP +G
Sbjct: 913 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972
Query: 825 -------------PFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSV 871
P P D P P K G G G + +++R G +
Sbjct: 973 CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG-------EL 1025
Query: 872 PIQGITLEEVSEIIGRDL 889
P+ + V ++ R L
Sbjct: 1026 PLGALQASVVQHLLSRTL 1043
Score = 34.3 bits (77), Expect = 0.54
Identities = 51/181 (28%), Positives = 65/181 (35%), Gaps = 42/181 (23%)
Query: 692 PLPDSSLRGFPSA--SATPFGTDMDFSPPRPP-------YPSYPHEDPACETPYLSEGFG 742
P PD++ P+ + P T + +PP P PS P P+ P ++
Sbjct: 318 PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377
Query: 743 YGMPPLYPQTGPP---------PSYR--PGLRMFPETRGTTGCAQPPAV---SFLPRPFP 788
P L QT PP PS + P + TT P SFL
Sbjct: 378 QAPPSL--QTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM--- 432
Query: 789 SDPYGGRGSSFSLGLPFSPPAPFRPP-----PLPASPPLE-------GPFPSQSDVHPLP 836
P + S S P S P P PP LPASPPL+ P S +HPL
Sbjct: 433 -SPRQTQASLTSPSRPASTP-PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490
Query: 837 A 837
A
Sbjct: 491 A 491
Score = 31.2 bits (69), Expect = 4.5
Identities = 38/137 (27%), Positives = 48/137 (35%), Gaps = 23/137 (16%)
Query: 698 LRGFPSASATPFGTDMDFSPP----RPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG 753
L P A+ +P GT PP P P+ P TP PL P
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL----------PLAP--- 345
Query: 754 PPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSD-----PYGGRGSSFSLGLPFSPP 808
P PS P L+ P T PP+++ P P P S S L +PP
Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ-APP 404
Query: 809 APFRPPPLPASPPLEGP 825
+P L A+ L P
Sbjct: 405 SPLALSSLQATTSLGSP 421
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 62.4 bits (150), Expect = 2e-09
Identities = 93/361 (25%), Positives = 121/361 (33%), Gaps = 80/361 (22%)
Query: 28 AGGLGEELDSEDAPPCCRLALGEP---PPYGA-------APIGIPRPPPPRPGMHSPPPR 77
A L E++ E++P L G P PP G +P G P+ PPP+ G + P
Sbjct: 16 AQNLNEDVSQEESPS---LIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGG--NQPQG 70
Query: 78 PAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDA 137
P P PG + P + G G G+ P S SP P P
Sbjct: 71 PPPPPGKPQGPPPQ-----GGNKPQGPPPPGKPQGPPPQGDKSRSP--RSPPGKPQGPPP 123
Query: 138 WGDGSPRDYPPPEGF-------GGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAA 190
G P+ PPP G GG + G G P P + S
Sbjct: 124 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR------------ 171
Query: 191 LYAACDEVESELNEAASRFGLGSPL-PSPRASPRPW-TPEDPWSLYGPSP-GGRGPEDSW 247
+SR G P P P+ +P P P GP P GG P+
Sbjct: 172 ---------------SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ--- 213
Query: 248 LLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLAR 307
GP P P P G + + S+ SP +G + G++P PPP
Sbjct: 214 ------GPPP----PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP----- 258
Query: 308 DPGSP-GPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEE--PASCNGKLPLGAEESVAP 364
PG P GP G P P + Q + RS P G P G + P
Sbjct: 259 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP 318
Query: 365 P 365
P
Sbjct: 319 P 319
Score = 49.3 bits (116), Expect = 2e-05
Identities = 59/190 (31%), Positives = 70/190 (36%), Gaps = 24/190 (12%)
Query: 717 PPRPPYPSYPHEDPACETPYLSEGFGYGMPPL---YPQTGPPPSYRPGLRMFPETRGTTG 773
PP P P D ++ G G PP PQ PPP PG P +G
Sbjct: 217 PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP---PGKPQGPPPQGGNK 273
Query: 774 CAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPA-PFRPPPLPASPPLEGPFPSQSDV 832
PP +P P GG S S SPP P PPP + P +GP P
Sbjct: 274 PQGPPPPG---KPQGPPPQGGSKSRSSR----SPPGKPQGPPPQGGNQP-QGPPPPPGKP 325
Query: 833 HPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVP--IQGITLEEVSEIIGRDLS 890
P +G NK P P G P+ +GG S S P QG +E G +
Sbjct: 326 QGPPPQGGNK--PQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQE-----GNNPQ 378
Query: 891 GFPAPPGEEP 900
G P P G P
Sbjct: 379 GPPPPAGGNP 388
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/221 (29%), Positives = 75/221 (33%), Gaps = 44/221 (19%)
Query: 692 PLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPH-EDPACETPYLSEGFGYGMPPL-- 748
P P +G P P G + PP P P P + +P G G PP
Sbjct: 72 PPPPGKPQGPP-----PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG 126
Query: 749 -YPQTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSP 807
PQ PPP PG P +G PP P P R S G P P
Sbjct: 127 NQPQGPPPP---PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP 183
Query: 808 P-----APFRPPPLPASPPLEGPFPSQSDVHPLPAEGYNKV--GPGYGPGEGAPEQ--EK 858
P P PPP P P +GP P +G NK P G +G P Q K
Sbjct: 184 PPQGGNQPQGPPPPPGKP--QGP----------PPQGGNKPQGPPPPGKPQGPPPQGDNK 231
Query: 859 SRGGYS-SGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGE 898
S+ S G P QG G G P PPG+
Sbjct: 232 SQSARSPPGKPQGPPPQG----------GNQPQGPPPPPGK 262
Score = 42.4 bits (98), Expect = 0.002
Identities = 54/185 (29%), Positives = 62/185 (33%), Gaps = 30/185 (16%)
Query: 733 ETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPR------- 785
E+P L G G PP P PG P +G PP P+
Sbjct: 27 ESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 86
Query: 786 ------PFPSDPYGGRGSSFSLGLPFSPPA-PFRPPPLPASPPLEGPFPSQSDVHPLPAE 838
P P P G P SPP P PPP + P +GP P P +
Sbjct: 87 NKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP-QGPPPPPGKPQGPPPQ 145
Query: 839 GYNKV--GPGYGPGEGAPEQ--EKSRGGYS-SGFRDSVPIQGITLEEVSEIIGRDLSGFP 893
G NK P G +G P Q KSR S G P QG G G P
Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQG----------GNQPQGPP 195
Query: 894 APPGE 898
PPG+
Sbjct: 196 PPPGK 200
Score = 38.9 bits (89), Expect = 0.022
Identities = 45/161 (27%), Positives = 61/161 (37%), Gaps = 21/161 (13%)
Query: 18 GEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPR 77
G+ + PP G + S +PP G PP G P G P PPP +P PPP+
Sbjct: 219 GKPQGPPPQG----DNKSQSARSPP--GKPQGPPPQGGNQPQG-PPPPPGKP--QGPPPQ 269
Query: 78 PA------PSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAAL 131
P PG + P + GG + + G+ + P + + P PP
Sbjct: 270 GGNKPQGPPPPGKPQGPPPQ----GGSKSRSSRSPPGKP-QGPPPQGGNQPQGPPPPPGK 324
Query: 132 EDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPG 172
P G P+ PPP G GG + SP PG
Sbjct: 325 PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP-PG 364
Score = 34.7 bits (78), Expect = 0.41
Identities = 48/160 (30%), Positives = 57/160 (35%), Gaps = 19/160 (11%)
Query: 716 SPPRPPYPSYPHEDPACETPYLSEGFGYGMPPL---YPQTGPPPSYRP------GLRMFP 766
SPP P P + P G G PP PQ GPPP +P G
Sbjct: 237 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ-GPPPPGKPQGPPPQGGSKSR 295
Query: 767 ETRGTTGCAQ--PPAVSFLPR---PFPSDPYGG--RGSSFSLGLPFSPPAPFRPPPLPAS 819
+R G Q PP P+ P P P G +G + G P P P PPP S
Sbjct: 296 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGGS 354
Query: 820 PPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKS 859
P P EG N GP P G P+Q ++
Sbjct: 355 KSRSARSPPGKPQGPPQQEGNNPQGPP-PPAGGNPQQPQA 393
Score = 32.7 bits (73), Expect = 1.6
Identities = 29/97 (29%), Positives = 36/97 (37%), Gaps = 22/97 (22%)
Query: 18 GEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPP-----PYGAAPIGIPRPPPPRPG-- 70
G+ + PP G + PP G PP P G P G P+ PPP+ G
Sbjct: 302 GKPQGPPPQGGN------QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK 355
Query: 71 ---MHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGG 104
SPP +P P + P GP AGG
Sbjct: 356 SRSARSPPGKPQGPPQQEGNNPQ------GPPPPAGG 386
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 62.0 bits (149), Expect = 2e-09
Identities = 106/364 (29%), Positives = 132/364 (36%), Gaps = 78/364 (21%)
Query: 22 EAPPLGAGGLGEELDSEDAPPCCRLALGEPP---PYGAAPIGIPRPPPPRPGMHSPPPRP 78
EA PLG G+ E E AP + L PP P P P PPP SPPP
Sbjct: 415 EAKPLGKAGVQLEPQLE-APLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEE 473
Query: 79 APSPGTWE----SQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPE--PPAALE 132
P+ E S+P L P E P +SP PE P + LE
Sbjct: 474 LPASPLPEALHLSRPLEESPLSPPPE-----------ESP------LSPPPESSPFSPLE 516
Query: 133 DNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALY 192
++P + P + PP SP P +S L S +E+ L
Sbjct: 517 ESPLS----PPEESPPSPAL-----------ETPLSPPPEASPL------SPPFEESPLS 555
Query: 193 AACDEVESELNEAASRFG---LGSPL-PSPRASPRPWTPEDPWSLYGP---SPGGRGPED 245
+E+ + ASR SP+ P P SP PE L+ P SP PE+
Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEAS-RLFPPFEESPLSPPPEE 614
Query: 246 SWL--------LLSAPGPTPASPRP-ASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSE 296
S L L P +P SP P SP S +P P +SR EE
Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP---LPVVSRLSPPPEESPL 671
Query: 297 PPPPPPLPLARDPG----SPGPFDYVGAPPAESIPQKTRRTSS------EQAVALPRSEE 346
PPP P + P SP P D +PP E P S E++ LP EE
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEE 731
Query: 347 PASC 350
P C
Sbjct: 732 PQLC 735
Score = 55.1 bits (131), Expect = 3e-07
Identities = 98/339 (28%), Positives = 119/339 (35%), Gaps = 78/339 (23%)
Query: 38 EDAPPCCRLALGEPPPYGAAPIG--------------IPRPPPPRPGMHSPPPRPAP-SP 82
E++PP L PP A+P+ +P PPP SPPP +P SP
Sbjct: 524 EESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP 583
Query: 83 GTWE---SQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWG 139
E S P + RL P E P SP PP A +P
Sbjct: 584 PPEESPMSPPPEASRLFPP-----------FEESPLSPPPEESPLSPPPEASRLSPPP-- 630
Query: 140 DGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSW---SFFSDASDEAALYAACD 196
+ SP PP E + SP P S LS S S +E+ L +
Sbjct: 631 EDSPMSPPPEE--------------SPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPE 676
Query: 197 EVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAP-GP 255
E + ASR P P SP PED SP PEDS L+S P
Sbjct: 677 ESPTSPPPEASRLS-----PPPEDSPTSPPPED-------SPASPPPEDS--LMSLPLEE 722
Query: 256 TPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPG-SPGP 314
+P P P P P S P LS R P P P A +P SP P
Sbjct: 723 SPLLPLPEEP--------QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP 774
Query: 315 FD-YVGAPPAES--IPQKTRRTSSEQAVAL---PRSEEP 347
+ + A P E PQ S Q L P++EEP
Sbjct: 775 EEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813
Score = 51.6 bits (122), Expect = 3e-06
Identities = 115/452 (25%), Positives = 145/452 (32%), Gaps = 111/452 (24%)
Query: 50 EPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPA--------------RSVRL 95
E P P P PPP SPPP +P+ E PA S L
Sbjct: 667 EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726
Query: 96 GGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPD----AWGDGSPRDYPPPE- 150
P CP +SP PE P L P+ + P P PE
Sbjct: 727 PLPE---------EPQLCPRSEGPHLSPRPEEPH-LSPRPEEPHLSPQAEEPHLSPQPEE 776
Query: 151 ----GFGGYREAGGQGGGAFFSPSPGSSSLSSWS---FFSDASDEAALYAACDEV----- 198
Q G SP P LS + S +E L +E
Sbjct: 777 PCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQ 836
Query: 199 --ESELNEAASRFGLGSPLPSPRASPRPWTP-EDPWSLYGPS-----PGGRGPEDSWLL- 249
E L+ L L P SPRP P E+P P P P S LL
Sbjct: 837 SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLG 896
Query: 250 ---LSAPGPTPASPRPA----SPCGKRRYSSSGTP-------------SSASPALSRRGS 289
LS PG P SP P SP G+ S P ++A PALS G
Sbjct: 897 EPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGE 956
Query: 290 L----GEEG-------------------------SEPPPPPPLPLARDPGSP-GPFDYVG 319
L G +G ++P P PP+ L PGSP GP
Sbjct: 957 LEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGP----- 1011
Query: 320 APPAESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGAEESVAPPGGSRKEVAGMDYL 378
A P P + + Q +P++ P+ C+ LPL ++P G +V G+
Sbjct: 1012 ASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIG----KVVGVSDE 1067
Query: 379 AVPSPLAWSKARIGGHSPIFRTSALPPLDWPL 410
A + K P SA PL P+
Sbjct: 1068 AELHEMETEKVS-EPECPALEPSATSPLPSPM 1098
Score = 50.4 bits (119), Expect = 7e-06
Identities = 101/412 (24%), Positives = 142/412 (34%), Gaps = 64/412 (15%)
Query: 41 PPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGG 100
PP + P+G AP P PR P P PSP +QP PG
Sbjct: 2164 PPQVPAQVPSQDPFGLAPA---YPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGA 2220
Query: 101 GAGGAGGGRVLECPSIRITSISPTPEPPAALEDN---PDAWGDGSPRDYPP---PEGFGG 154
G G P + ++ P +P DN P++ G G + P P FG
Sbjct: 2221 GQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE 2280
Query: 155 YR---EAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEV-ESELNEAASRFG 210
R E + GA SPS G +L S + L +V ++ L AS+
Sbjct: 2281 SRKALEVKKEELGA-SSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVE 2339
Query: 211 LGSP---------------LPSPRASP---RPWTPEDPWSLYGPSPGGRGPEDSWLLLSA 252
SP PSP + P RP + DP++ +P + P
Sbjct: 2340 PQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALP 2399
Query: 253 PGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPL-----PLAR 307
P P+ P P + SSS +P + P L E P P P P +R
Sbjct: 2400 PRSLPSDPFSRVPASPQSQSSSQSPLTPRP-------LSAEAFCPSPVTPRFQSPDPYSR 2452
Query: 308 DPGSP---GPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPAS--------CNGKLPL 356
P P PF + PP P+ + S +L PA+ + K+P
Sbjct: 2453 PPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS 2512
Query: 357 GAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGH---SPIFRTSALPP 405
G PP R G ++ PSP+ ++ + G P LPP
Sbjct: 2513 G-----QPPNFVRSPGTGA-FVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPP 2558
Score = 47.0 bits (110), Expect = 8e-05
Identities = 56/194 (28%), Positives = 66/194 (34%), Gaps = 23/194 (11%)
Query: 677 PTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPY 736
P +S F P+ +E PL A TP + SP PP+ P P E P
Sbjct: 506 PPESSPFSPL--EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPT 563
Query: 737 LS--EGFGYGMPPLYPQTGPPPSYRP------GLRMFPETRGTTGCAQPPAVSFLPRPFP 788
E PP PPP P R+FP + + PP S L P
Sbjct: 564 SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP-LSPPPEESPLSPP-- 620
Query: 789 SDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLE----GPFPSQSDVHPLPAEGYNKVG 844
P R S P SPP P P SPP E P P S + P P E
Sbjct: 621 --PEASRLSPPPEDSPMSPP----PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
Query: 845 PGYGPGEGAPEQEK 858
P P PE +
Sbjct: 675 PEESPTSPPPEASR 688
Score = 45.8 bits (107), Expect = 2e-04
Identities = 82/328 (25%), Positives = 112/328 (34%), Gaps = 50/328 (15%)
Query: 36 DSEDAPPCCRLALGEPPPYGAA---PIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPARS 92
DS +PP + PP P+ PPP SPPP +P+ S P +
Sbjct: 632 DSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT-----SPPPEA 686
Query: 93 VRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAA---LEDNPDAWGDGSPRDYPPP 149
RL P + + P + SP PE LE++P P+ P
Sbjct: 687 SRLSPPPEDSPTS--------PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
Query: 150 EGFGGYREAGGQGGGAFFSPSPGSSSLSSWS---FFSDASDEAALYAACDEVESELNEAA 206
EG + SP P LS + S +E L A +E
Sbjct: 739 EG----PHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPH------- 787
Query: 207 SRFGLGSPLPSPRASPRP----WTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRP 262
L P SP+P +P+ P P + L P + SP+
Sbjct: 788 ----LSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP------EEPCLSPQPEESHLSPQS 837
Query: 263 ASPC-GKRRYSSSGTPSSASPALSRRGSLG-EEGSEPPPPPPLPLARDPGSPGPFDYVGA 320
PC R S +P P LS R EE + P P LPL PG P +G
Sbjct: 838 EEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLG- 896
Query: 321 PPAESIPQKTRRTSSEQAVALPRSEEPA 348
PA S P + + + + L S EP+
Sbjct: 897 EPALSEPGEPPLSPLPEELPLSPSGEPS 924
Score = 41.2 bits (95), Expect = 0.004
Identities = 40/127 (31%), Positives = 45/127 (35%), Gaps = 24/127 (18%)
Query: 717 PPRPPYPSYPHEDPA-CETPYLSEGFGY-GMPPLYPQTGPPPSYRPGLRMFPETRGTTGC 774
PP P P P E+P C P F G P L P G P PG
Sbjct: 858 PPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPG------------- 904
Query: 775 AQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPP-------LEGPFP 827
P +S LP P P G S L P P P P A+PP LE PF
Sbjct: 905 --EPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFG 962
Query: 828 SQSDVHP 834
++ D P
Sbjct: 963 AKGDSDP 969
Score = 41.2 bits (95), Expect = 0.004
Identities = 89/312 (28%), Positives = 109/312 (34%), Gaps = 66/312 (21%)
Query: 47 ALGEP--PPYGAAPIGIPRPPPPRPGMHSP---PPRPAPSPG----TWESQPARSV--RL 95
AL EP PP P +P P P + SP PP P P P T + PA S L
Sbjct: 899 ALSEPGEPPLSPLPEELPLSPSGEPSL-SPQLMPPDPLPPPLSPIITAAAPPALSPLGEL 957
Query: 96 GGPGGGAGGAGGGRVLECPSIRITSISPTPE---------PPAALEDNPDA-WGDGSP-- 143
P G G + L P + T ISP PE PP L +P + G SP
Sbjct: 958 EYPFGAKGDSDPESPLAAPILE-TPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPIL 1016
Query: 144 RDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSD------ASDEAALYAACDE 197
+ PP+ + + SP + LS S S SDEA L+ E
Sbjct: 1017 MEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETE 1076
Query: 198 VESELNEAASRFGLGSPLPSPRA-----SPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSA 252
SE A SPLPSP +P P D +S G P D + A
Sbjct: 1077 KVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGED---TAPLDG---IDA 1130
Query: 253 PGPTPASPRPASPCGKRRYSSSGTPSSASP----------------ALSRRGSLGEEGSE 296
PG + P P G G+P P + +GS EE E
Sbjct: 1131 PG---SQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEE 1187
Query: 297 P-----PPPPPL 303
P P PP L
Sbjct: 1188 PRAPVAPTPPTL 1199
Score = 38.1 bits (87), Expect = 0.037
Identities = 35/95 (36%), Positives = 38/95 (40%), Gaps = 12/95 (12%)
Query: 250 LSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEG-SEPPPPPPLPLARD 308
LSAP P SP P SP PS ASP L E +EPP P PLPLA
Sbjct: 4906 LSAPPPEEPSP-PPSPLA---------PSPASPPTEPLVELPTEPLAEPPVPSPLPLASS 4955
Query: 309 PGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPR 343
P S P PP E + R + V R
Sbjct: 4956 PESARPKPR-ARPPEEGEDSRPPRLKKWKGVRWKR 4989
Score = 37.7 bits (86), Expect = 0.049
Identities = 93/368 (25%), Positives = 120/368 (32%), Gaps = 74/368 (20%)
Query: 20 EKEAPPLGAGGLGEELDSEDAPPCCRLALGEPP------------PYGAAPIGIPRPPPP 67
E ++P LG L ++ PP LA P PY P+ PRP PP
Sbjct: 2339 EPQSPGLG-------LRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL-TPRPQPP 2390
Query: 68 RP-GMHSPPPRPAPS------PGTWESQPARSVRLGGPGGGAGGAGGGRVLECPS---IR 117
P + PPR PS P + +SQ + L A CPS R
Sbjct: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAF-------CPSPVTPR 2443
Query: 118 ITSISPTPEPPAALED-NPDAWGDGSPRDYPPPEGF-GGYREAGGQGGGAFFSPSPGSSS 175
S P PP+ + +P A PR PP F G G G F + P
Sbjct: 2444 FQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALP---- 2499
Query: 176 LSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYG 235
A L+A + + G PSP P +P SL
Sbjct: 2500 ---------AGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP-SLKP 2549
Query: 236 PSP-GGRGPEDSWLLLSAPGPTPASPRPAS-PCGKRRYSSSGTPSSASPALSRRGSLGEE 293
P P G P PGPT P+ + + SG+P S GS GE
Sbjct: 2550 PVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPS-----SGSTGES 2604
Query: 294 GSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALP--RSEEPASCN 351
P PP L P P P S+P + S + P + E+P +
Sbjct: 2605 YGLSPLRPPSVL------PPP------APDGSLPYLSHGASQRSGITSPVEKREDPGTGM 2652
Query: 352 GKLPLGAE 359
G AE
Sbjct: 2653 GSSLATAE 2660
Score = 33.1 bits (74), Expect = 1.2
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 717 PPRPPYPSYP-HEDPACETPYLSEGFGY-GMPPLYPQTGPPPSYRPGLRMFPETRGTTGC 774
P RP + YP EDP P G G+PP P P P L P T+G T
Sbjct: 2901 PQRPRF--YPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPT-- 2956
Query: 775 AQPPAVSFLPRPFPSDPYGGRGSSFSL 801
P + + RP PS GR + +L
Sbjct: 2957 -LPTGLELVNRP-PSSTELGRPNPLAL 2981
Score = 32.7 bits (73), Expect = 1.6
Identities = 43/143 (30%), Positives = 52/143 (36%), Gaps = 20/143 (13%)
Query: 723 PSYPHEDPACETPYLS---EGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPA 779
P PH P E P+LS E P P P P L PE + ++ P
Sbjct: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPE-EPCLSPQPEESHLSPQSEEPC 841
Query: 780 VSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPP------PLPASPPLEGPFPSQSDVH 833
+S PRP S S L P P P +PP P P PL P P + +
Sbjct: 842 LS--PRPEESH------LSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP-PGEPSLS 892
Query: 834 PLPAEGYNKVGPGYGPGEGAPEQ 856
PL E PG P PE+
Sbjct: 893 PLLGEPALS-EPGEPPLSPLPEE 914
Score = 32.7 bits (73), Expect = 1.6
Identities = 62/261 (23%), Positives = 84/261 (32%), Gaps = 37/261 (14%)
Query: 673 RKRSPTQSFRFLPVICKEEPLPDSSLRGFPSAS----------ATPFGTDMDFSPPRPPY 722
R S T + P+ + +P P S P S A+P SP P
Sbjct: 2370 RPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRP 2429
Query: 723 PSYPHEDPACETPYLSEGFGYGMPPLYPQTGPP--PSYRPGLRMFPETRGTTGCAQPPAV 780
S P+ TP Y PP PQ+ P P ++P PE G ++
Sbjct: 2430 LSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSL 2489
Query: 781 SF--LPRPFPSDPYGGRGSSFSLGLP------------FSPPAP--FRPPPLPASPPLEG 824
P P+ P G + G P P+P F P P L+
Sbjct: 2490 GAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKP 2549
Query: 825 PFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEK---SRGGYSSGFRDSVPIQGITLEE- 880
P P P P + GP GP G P+ + G + P G T E
Sbjct: 2550 PVPQPG--LPPPHGINSHFGP--GPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESY 2605
Query: 881 -VSEIIGRDLSGFPAPPGEEP 900
+S + + PAP G P
Sbjct: 2606 GLSPLRPPSVLPPPAPDGSLP 2626
Score = 31.6 bits (70), Expect = 3.5
Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 24/102 (23%)
Query: 754 PPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPS-DPYGGRGSSFSLGLPFSPPAPFR 812
PP PG P++ G PP V P PS DP+G +P P
Sbjct: 2145 PPAGSVPG----PDSPGELFLKLPPQV---PAQVPSQDPFG-----------LAPAYPLE 2186
Query: 813 PPPLPASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAP 854
P P +PP P+PS + P +G PG G P
Sbjct: 2187 PR-FPTAPPTYPPYPSPTGAPAQPP----MLGASSRPGAGQP 2223
Score = 31.6 bits (70), Expect = 3.5
Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 13/79 (16%)
Query: 235 GPSPGG--RGPEDSWLLLSAP--GPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSL 290
GP P G R P L + P GP +P P+SP +R S +PSS P
Sbjct: 4280 GPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPT------- 4332
Query: 291 GEEGSEPPPPPPLPLARDP 309
E PP P P + P
Sbjct: 4333 --EAQLPPTHPGTPKPQGP 4349
Score = 31.2 bits (69), Expect = 4.5
Identities = 27/82 (32%), Positives = 31/82 (37%), Gaps = 13/82 (15%)
Query: 755 PPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPP 814
PP PG + P +G GC P + P P G LG + P P PP
Sbjct: 4241 PPYQEPGTQTSP-LQGLLGCQ--PQLGGFPGP-------QTGPLQELG---AGPRPQGPP 4287
Query: 815 PLPASPPLEGPFPSQSDVHPLP 836
LPA P P VHP P
Sbjct: 4288 RLPAPPGALSTGPVLGPVHPTP 4309
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
sapiens]
Length = 1650
Score = 61.2 bits (147), Expect = 4e-09
Identities = 104/380 (27%), Positives = 121/380 (31%), Gaps = 73/380 (19%)
Query: 25 PLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSP---------P 75
P AGG G L + P G P GAA G P PP RPG P P
Sbjct: 907 PGTAGGPG--LKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 964
Query: 76 PRPAPSPGTWESQPARSVRLGGPGGGAGGAG----GGRVLECPSIRITSIS------PTP 125
P T V L GP G G AG G V + P + T + P P
Sbjct: 965 GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD-PGQKGTKGNKGEHGPPGP 1023
Query: 126 EPPAALEDNPDAWG-DGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSD 184
P P A G DG P P FG + G +G F+ PG L
Sbjct: 1024 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG----FNGPPGPIGLQ------- 1072
Query: 185 ASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPS--PGGRG 242
E E +G P P P P P P GP PGG G
Sbjct: 1073 ---------GLPGPSGEKGETGDVGPMGPPGP-----PGPRGPAGPNGADGPQGPPGGVG 1118
Query: 243 PEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSR--RGSLGEEGSEPPPP 300
L PG SP G P P R +G G+ G PP
Sbjct: 1119 N------LGPPGEKGEPGESGSP------GIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1166
Query: 301 PPLPLARD--PGSPGPFDYVG--APPAESIPQKTRRTSSEQA----VALPRSEEPASCNG 352
P P D G+PGP + G PP E P+ ++ P S P NG
Sbjct: 1167 PKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1226
Query: 353 KL-PLGAEESVAPPGGSRKE 371
PLG PG ++
Sbjct: 1227 PPGPLGKRGPAGSPGSEGRQ 1246
Score = 55.5 bits (132), Expect = 2e-07
Identities = 98/375 (26%), Positives = 123/375 (32%), Gaps = 79/375 (21%)
Query: 29 GGLGEELDS----EDAPPCCRLALGEPPPYG-AAPIGIPRPPPPRPGMHSP--------- 74
G GE+ +S E PP + G+ P G P+G P P P PG P
Sbjct: 1148 GERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP-PGEGGPRGQDGAKGD 1206
Query: 75 ------PPRPAPSPGTWESQPARSVRLGGPGGGAGGAG--GGRVLECPSIRITSISPT-P 125
P +P T E+ P + GP G G G GG+ + I + T P
Sbjct: 1207 RGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGP 1266
Query: 126 EPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDA 185
PA P G R P G G A GQ G PG L +
Sbjct: 1267 VGPAGPAGKP---GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1323
Query: 186 SDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPED 245
L E E R LP P+ SP PG GP
Sbjct: 1324 KGHPGLIGLIGP-PGEQGEKGDR-----GLPGPQGSPGQKGEMG-------IPGASGP-- 1368
Query: 246 SWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPL 305
PG P P PA P G + + G P GE+G + P
Sbjct: 1369 -----IGPGGPPGLPGPAGPKGAKGATGPGGPK------------GEKGVQGP------- 1404
Query: 306 ARDPGSPGPFDYVGAPPAESIPQKTRRTSS-----EQAVALPRSEEPASCNGKLPLGAEE 360
PG PGP V P +P+KTRR+ ++ A+P P S P G EE
Sbjct: 1405 ---PGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGS-----PGGLEE 1456
Query: 361 SVAPPGGSRKEVAGM 375
R+E+ M
Sbjct: 1457 IFGSLDSLREEIEQM 1471
Score = 54.3 bits (129), Expect = 5e-07
Identities = 101/390 (25%), Positives = 127/390 (32%), Gaps = 86/390 (22%)
Query: 53 PYGAAPIGIPRPPPPRPG-MHSP----PPRPAPSPGTWES------QPARSVRLGGPGGG 101
P P R P +P +H P P P+PG E P GP G
Sbjct: 236 PQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGL 295
Query: 102 AGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQ 161
G G VLE P + + P PE PA L P G+ P P G G R G+
Sbjct: 296 KGEKGEPAVLE-PGMLVEG-PPGPEGPAGLIGPPGIQGN------PGPVGDPGERGPPGR 347
Query: 162 GG--GAFFSPS-PGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSP---- 214
G G+ +P PG+S + + F S D+ + AA E +++ +R L P
Sbjct: 348 AGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAA-QEAQAQAILQQARLALRGPPGPM 406
Query: 215 ----LPSPRASP------------RPWTPEDPWSLYGP--------------------SP 238
P P P P P P L GP P
Sbjct: 407 GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 466
Query: 239 GGRGPEDSWLLLSAPGP--------TPASPRPASPCGKR----RYSSSGTPSSASPALSR 286
G +G L PG P P G+R G P + P
Sbjct: 467 GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP---- 522
Query: 287 RGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVG-----APPAESIPQKTRRTSSEQAVAL 341
RG LG +G P PP D G GP +G PP + T+ Q
Sbjct: 523 RGLLGPKGPPGIPGPPGVRGMD-GPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 581
Query: 342 PRSEEPASCNGKLPLGAEESVAPPGGSRKE 371
P E+ LP G S PPG KE
Sbjct: 582 PHGEKGPQGKPGLP-GMPGSDGPPGHPGKE 610
Score = 45.4 bits (106), Expect = 2e-04
Identities = 93/361 (25%), Positives = 114/361 (31%), Gaps = 76/361 (21%)
Query: 18 GEEKEAPPLGAGGL-------GEELDSEDAPPCCRLALGEPPPYGA----APIGIPRPPP 66
GE+ GA GL GE D + P R GE P G P GIP PP
Sbjct: 482 GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGP--RGLPGESGPRGLLGPKGPPGIPGPPG 539
Query: 67 PRPGMHSPP-------PRPAPSPGTWESQPARSVRLG-----GPGGGAGGAGGGRVLECP 114
R GM P P+ P P + P G GP G G G + P
Sbjct: 540 VR-GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 598
Query: 115 SIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPP---EGFGGYREAGGQGGGAFFSPSP 171
P E P + N G P YP P +G G R G G P
Sbjct: 599 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFP 658
Query: 172 GSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLP-SPRASPRPWTPEDP 230
G F D V+ + E G P P+ P P
Sbjct: 659 G--------FKGDIG-----------VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 699
Query: 231 WSLYGPS-----------PGGRGPEDSWLLLSAPGPTPASPR--------PASPCGKRRY 271
L G PG +GP+ S L PG AS + P G+R
Sbjct: 700 PGLMGEKGKLGVPGLPGYPGRQGPKGS---LGFPGFPGASGEKGARGLSGKSGPRGERGP 756
Query: 272 SSSGTPSSASPALSRRGSLGEEGSEPPPPPP----LPLARDP-GSPGPFDYVGAPPAESI 326
+ A + G+ G G + P PP LP + P G PGP G P + +
Sbjct: 757 TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 816
Query: 327 P 327
P
Sbjct: 817 P 817
Score = 38.1 bits (87), Expect = 0.037
Identities = 95/387 (24%), Positives = 115/387 (29%), Gaps = 85/387 (21%)
Query: 49 GEPPPYGA-APIGIPRPP-----PPRPGMHSPPPRPAPS--PGTWESQPARSVR--LGGP 98
G P P GA P G P P PG PP P PGT +Q + LG P
Sbjct: 572 GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 631
Query: 99 GG-GAGGAGGGRVLE----------CPSIRIT-----SISPTPEPPAALEDNPDA-WGDG 141
G G G G R L+ P + P + ED P+ G
Sbjct: 632 GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 691
Query: 142 SPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESE 201
P P P G G + G G + G + F AS E
Sbjct: 692 GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS------ 745
Query: 202 LNEAASRFGLGSPLPSPRASPR----------------PWTPEDPWSLYGPS-----PGG 240
++ R G P + PR P P L GP PG
Sbjct: 746 -GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 804
Query: 241 RGPEDSWLLLSAPGPTPASPRPASPCGKR-------RYSSSGTPSSASP--ALSRRGSLG 291
+GP PGP P P G+R + G P P A G +G
Sbjct: 805 KGP---------PGPPGKDGLPGHP-GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 854
Query: 292 EEGSEPPPPPP----LP-------LARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVA 340
E G PP PP LP DPG PG G P + +
Sbjct: 855 ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPG 914
Query: 341 LPRSEEPASCNGKLPLGAEESVAPPGG 367
L +E P+ G E A GG
Sbjct: 915 LKGNEGPSGPPGPAGSPGERGAAGSGG 941
Score = 34.7 bits (78), Expect = 0.41
Identities = 57/204 (27%), Positives = 68/204 (33%), Gaps = 21/204 (10%)
Query: 702 PSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPG 761
P +A G + P PP P P E T G PP P P G
Sbjct: 843 PQGAAGETGPMGERGHPGPPGP--PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA----G 896
Query: 762 LRMFPETRGTTGCAQPPAVSFLPRPF----PSDPYGGRGSSFSLGLPFSPPAPFRPPPLP 817
LR FP RG G A P + P P+ G RG++ S G P PP P P
Sbjct: 897 LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS-GGPIGPPGRPGPQGPP 955
Query: 818 ASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGIT 877
+ +G + + P +G GP PG P G D P Q T
Sbjct: 956 GAAGEKGVPGEKGPIGPTGRDGVQ--GPVGLPGPAGPPGVAGEDGDKGEVGD--PGQKGT 1011
Query: 878 LEEVSEIIGRDLSGFPAPPGEEPP 901
E G P PPG P
Sbjct: 1012 KGNKGE------HGPPGPPGPIGP 1029
Score = 32.7 bits (73), Expect = 1.6
Identities = 51/201 (25%), Positives = 58/201 (28%), Gaps = 40/201 (19%)
Query: 702 PSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPG 761
PS G PP PP P P + P G P GP PG
Sbjct: 1077 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP-------QGPPGGVGNLGP-----PG 1124
Query: 762 LRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPP 821
+ P G+ G P V P G RG G P P P P P
Sbjct: 1125 EKGEPGESGSPGIQGEPGV--------KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGP 1176
Query: 822 LEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEV 881
P P P P PGEG P + G D P Q +
Sbjct: 1177 KGNPGPVGFPGDPGP------------PGEGGPRGQD--GAKGDRGEDGEPGQPGSPGPT 1222
Query: 882 SEIIGRDLSGFPAPPGEEPPA 902
E +G P P G+ PA
Sbjct: 1223 GE------NGPPGPLGKRGPA 1237
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
sapiens]
Length = 1629
Score = 61.2 bits (147), Expect = 4e-09
Identities = 104/380 (27%), Positives = 121/380 (31%), Gaps = 73/380 (19%)
Query: 25 PLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSP---------P 75
P AGG G L + P G P GAA G P PP RPG P P
Sbjct: 886 PGTAGGPG--LKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 943
Query: 76 PRPAPSPGTWESQPARSVRLGGPGGGAGGAG----GGRVLECPSIRITSIS------PTP 125
P T V L GP G G AG G V + P + T + P P
Sbjct: 944 GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD-PGQKGTKGNKGEHGPPGP 1002
Query: 126 EPPAALEDNPDAWG-DGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSD 184
P P A G DG P P FG + G +G F+ PG L
Sbjct: 1003 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG----FNGPPGPIGLQ------- 1051
Query: 185 ASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPS--PGGRG 242
E E +G P P P P P P GP PGG G
Sbjct: 1052 ---------GLPGPSGEKGETGDVGPMGPPGP-----PGPRGPAGPNGADGPQGPPGGVG 1097
Query: 243 PEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSR--RGSLGEEGSEPPPP 300
L PG SP G P P R +G G+ G PP
Sbjct: 1098 N------LGPPGEKGEPGESGSP------GIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1145
Query: 301 PPLPLARD--PGSPGPFDYVG--APPAESIPQKTRRTSSEQA----VALPRSEEPASCNG 352
P P D G+PGP + G PP E P+ ++ P S P NG
Sbjct: 1146 PKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1205
Query: 353 KL-PLGAEESVAPPGGSRKE 371
PLG PG ++
Sbjct: 1206 PPGPLGKRGPAGSPGSEGRQ 1225
Score = 55.5 bits (132), Expect = 2e-07
Identities = 98/375 (26%), Positives = 123/375 (32%), Gaps = 79/375 (21%)
Query: 29 GGLGEELDS----EDAPPCCRLALGEPPPYG-AAPIGIPRPPPPRPGMHSP--------- 74
G GE+ +S E PP + G+ P G P+G P P P PG P
Sbjct: 1127 GERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP-PGEGGPRGQDGAKGD 1185
Query: 75 ------PPRPAPSPGTWESQPARSVRLGGPGGGAGGAG--GGRVLECPSIRITSISPT-P 125
P +P T E+ P + GP G G G GG+ + I + T P
Sbjct: 1186 RGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGP 1245
Query: 126 EPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDA 185
PA P G R P G G A GQ G PG L +
Sbjct: 1246 VGPAGPAGKP---GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1302
Query: 186 SDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPED 245
L E E R LP P+ SP PG GP
Sbjct: 1303 KGHPGLIGLIGP-PGEQGEKGDR-----GLPGPQGSPGQKGEMG-------IPGASGP-- 1347
Query: 246 SWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPL 305
PG P P PA P G + + G P GE+G + P
Sbjct: 1348 -----IGPGGPPGLPGPAGPKGAKGATGPGGPK------------GEKGVQGP------- 1383
Query: 306 ARDPGSPGPFDYVGAPPAESIPQKTRRTSS-----EQAVALPRSEEPASCNGKLPLGAEE 360
PG PGP V P +P+KTRR+ ++ A+P P S P G EE
Sbjct: 1384 ---PGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGS-----PGGLEE 1435
Query: 361 SVAPPGGSRKEVAGM 375
R+E+ M
Sbjct: 1436 IFGSLDSLREEIEQM 1450
Score = 53.9 bits (128), Expect = 7e-07
Identities = 95/370 (25%), Positives = 123/370 (33%), Gaps = 76/370 (20%)
Query: 62 PRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSI 121
P+ P SP +P+ +P +S GP G G G VLE P + +
Sbjct: 236 PQNQQPHRAQRSPQQQPSRLHRPQNQEP-QSQAAHGPRGLKGEKGEPAVLE-PGMLVEG- 292
Query: 122 SPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGG--GAFFSPS-PGSSSLSS 178
P PE PA L P G+ P P G G R G+ G G+ +P PG+S +
Sbjct: 293 PPGPEGPAGLIGPPGIQGN------PGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLP 346
Query: 179 WSFFSDASDEAALYAACDEVESELNEAASRFGLGSP--------LPSPRASP-------- 222
+ F S D+ + AA E +++ +R L P P P P
Sbjct: 347 FRFGSGGGDKGPVVAA-QEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 405
Query: 223 ----RPWTPEDPWSLYGP--------------------SPGGRGPEDSWLLLSAPGP--- 255
P P P L GP PG +G L PG
Sbjct: 406 SGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 465
Query: 256 -----TPASPRPASPCGKR----RYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLA 306
P P G+R G P + P RG LG +G P PP
Sbjct: 466 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP----RGLLGPKGPPGIPGPPGVRG 521
Query: 307 RDPGSPGPFDYVG-----APPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEES 361
D G GP +G PP + T+ Q P E+ LP G S
Sbjct: 522 MD-GPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLP-GMPGS 579
Query: 362 VAPPGGSRKE 371
PPG KE
Sbjct: 580 DGPPGHPGKE 589
Score = 45.4 bits (106), Expect = 2e-04
Identities = 93/361 (25%), Positives = 114/361 (31%), Gaps = 76/361 (21%)
Query: 18 GEEKEAPPLGAGGL-------GEELDSEDAPPCCRLALGEPPPYGA----APIGIPRPPP 66
GE+ GA GL GE D + P R GE P G P GIP PP
Sbjct: 461 GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGP--RGLPGESGPRGLLGPKGPPGIPGPPG 518
Query: 67 PRPGMHSPP-------PRPAPSPGTWESQPARSVRLG-----GPGGGAGGAGGGRVLECP 114
R GM P P+ P P + P G GP G G G + P
Sbjct: 519 VR-GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 577
Query: 115 SIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPP---EGFGGYREAGGQGGGAFFSPSP 171
P E P + N G P YP P +G G R G G P
Sbjct: 578 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFP 637
Query: 172 GSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLP-SPRASPRPWTPEDP 230
G F D V+ + E G P P+ P P
Sbjct: 638 G--------FKGDIG-----------VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 678
Query: 231 WSLYGPS-----------PGGRGPEDSWLLLSAPGPTPASPR--------PASPCGKRRY 271
L G PG +GP+ S L PG AS + P G+R
Sbjct: 679 PGLMGEKGKLGVPGLPGYPGRQGPKGS---LGFPGFPGASGEKGARGLSGKSGPRGERGP 735
Query: 272 SSSGTPSSASPALSRRGSLGEEGSEPPPPPP----LPLARDP-GSPGPFDYVGAPPAESI 326
+ A + G+ G G + P PP LP + P G PGP G P + +
Sbjct: 736 TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 795
Query: 327 P 327
P
Sbjct: 796 P 796
Score = 38.1 bits (87), Expect = 0.037
Identities = 95/387 (24%), Positives = 115/387 (29%), Gaps = 85/387 (21%)
Query: 49 GEPPPYGA-APIGIPRPP-----PPRPGMHSPPPRPAPS--PGTWESQPARSVR--LGGP 98
G P P GA P G P P PG PP P PGT +Q + LG P
Sbjct: 551 GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 610
Query: 99 GG-GAGGAGGGRVLE----------CPSIRIT-----SISPTPEPPAALEDNPDA-WGDG 141
G G G G R L+ P + P + ED P+ G
Sbjct: 611 GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 670
Query: 142 SPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESE 201
P P P G G + G G + G + F AS E
Sbjct: 671 GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS------ 724
Query: 202 LNEAASRFGLGSPLPSPRASPR----------------PWTPEDPWSLYGPS-----PGG 240
++ R G P + PR P P L GP PG
Sbjct: 725 -GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783
Query: 241 RGPEDSWLLLSAPGPTPASPRPASPCGKR-------RYSSSGTPSSASP--ALSRRGSLG 291
+GP PGP P P G+R + G P P A G +G
Sbjct: 784 KGP---------PGPPGKDGLPGHP-GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 833
Query: 292 EEGSEPPPPPP----LP-------LARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVA 340
E G PP PP LP DPG PG G P + +
Sbjct: 834 ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPG 893
Query: 341 LPRSEEPASCNGKLPLGAEESVAPPGG 367
L +E P+ G E A GG
Sbjct: 894 LKGNEGPSGPPGPAGSPGERGAAGSGG 920
Score = 34.7 bits (78), Expect = 0.41
Identities = 57/204 (27%), Positives = 68/204 (33%), Gaps = 21/204 (10%)
Query: 702 PSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPG 761
P +A G + P PP P P E T G PP P P G
Sbjct: 822 PQGAAGETGPMGERGHPGPPGP--PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA----G 875
Query: 762 LRMFPETRGTTGCAQPPAVSFLPRPF----PSDPYGGRGSSFSLGLPFSPPAPFRPPPLP 817
LR FP RG G A P + P P+ G RG++ S G P PP P P
Sbjct: 876 LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS-GGPIGPPGRPGPQGPP 934
Query: 818 ASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGIT 877
+ +G + + P +G GP PG P G D P Q T
Sbjct: 935 GAAGEKGVPGEKGPIGPTGRDGVQ--GPVGLPGPAGPPGVAGEDGDKGEVGD--PGQKGT 990
Query: 878 LEEVSEIIGRDLSGFPAPPGEEPP 901
E G P PPG P
Sbjct: 991 KGNKGE------HGPPGPPGPIGP 1008
Score = 32.7 bits (73), Expect = 1.6
Identities = 51/201 (25%), Positives = 58/201 (28%), Gaps = 40/201 (19%)
Query: 702 PSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPG 761
PS G PP PP P P + P G P GP PG
Sbjct: 1056 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP-------QGPPGGVGNLGP-----PG 1103
Query: 762 LRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPP 821
+ P G+ G P V P G RG G P P P P P
Sbjct: 1104 EKGEPGESGSPGIQGEPGV--------KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGP 1155
Query: 822 LEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEV 881
P P P P PGEG P + G D P Q +
Sbjct: 1156 KGNPGPVGFPGDPGP------------PGEGGPRGQD--GAKGDRGEDGEPGQPGSPGPT 1201
Query: 882 SEIIGRDLSGFPAPPGEEPPA 902
E +G P P G+ PA
Sbjct: 1202 GE------NGPPGPLGKRGPA 1216
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 61.2 bits (147), Expect = 4e-09
Identities = 104/380 (27%), Positives = 121/380 (31%), Gaps = 73/380 (19%)
Query: 25 PLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSP---------P 75
P AGG G L + P G P GAA G P PP RPG P P
Sbjct: 993 PGTAGGPG--LKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 1050
Query: 76 PRPAPSPGTWESQPARSVRLGGPGGGAGGAG----GGRVLECPSIRITSIS------PTP 125
P T V L GP G G AG G V + P + T + P P
Sbjct: 1051 GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD-PGQKGTKGNKGEHGPPGP 1109
Query: 126 EPPAALEDNPDAWG-DGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSD 184
P P A G DG P P FG + G +G F+ PG L
Sbjct: 1110 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG----FNGPPGPIGLQ------- 1158
Query: 185 ASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPS--PGGRG 242
E E +G P P P P P P GP PGG G
Sbjct: 1159 ---------GLPGPSGEKGETGDVGPMGPPGP-----PGPRGPAGPNGADGPQGPPGGVG 1204
Query: 243 PEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSR--RGSLGEEGSEPPPP 300
L PG SP G P P R +G G+ G PP
Sbjct: 1205 N------LGPPGEKGEPGESGSP------GIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1252
Query: 301 PPLPLARD--PGSPGPFDYVG--APPAESIPQKTRRTSSEQA----VALPRSEEPASCNG 352
P P D G+PGP + G PP E P+ ++ P S P NG
Sbjct: 1253 PKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1312
Query: 353 KL-PLGAEESVAPPGGSRKE 371
PLG PG ++
Sbjct: 1313 PPGPLGKRGPAGSPGSEGRQ 1332
Score = 55.5 bits (132), Expect = 2e-07
Identities = 98/375 (26%), Positives = 123/375 (32%), Gaps = 79/375 (21%)
Query: 29 GGLGEELDS----EDAPPCCRLALGEPPPYG-AAPIGIPRPPPPRPGMHSP--------- 74
G GE+ +S E PP + G+ P G P+G P P P PG P
Sbjct: 1234 GERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP-PGEGGPRGQDGAKGD 1292
Query: 75 ------PPRPAPSPGTWESQPARSVRLGGPGGGAGGAG--GGRVLECPSIRITSISPT-P 125
P +P T E+ P + GP G G G GG+ + I + T P
Sbjct: 1293 RGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGP 1352
Query: 126 EPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDA 185
PA P G R P G G A GQ G PG L +
Sbjct: 1353 VGPAGPAGKP---GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1409
Query: 186 SDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPED 245
L E E R LP P+ SP PG GP
Sbjct: 1410 KGHPGLIGLIGP-PGEQGEKGDR-----GLPGPQGSPGQKGEMG-------IPGASGP-- 1454
Query: 246 SWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPL 305
PG P P PA P G + + G P GE+G + P
Sbjct: 1455 -----IGPGGPPGLPGPAGPKGAKGATGPGGPK------------GEKGVQGP------- 1490
Query: 306 ARDPGSPGPFDYVGAPPAESIPQKTRRTSS-----EQAVALPRSEEPASCNGKLPLGAEE 360
PG PGP V P +P+KTRR+ ++ A+P P S P G EE
Sbjct: 1491 ---PGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGS-----PGGLEE 1542
Query: 361 SVAPPGGSRKEVAGM 375
R+E+ M
Sbjct: 1543 IFGSLDSLREEIEQM 1557
Score = 49.3 bits (116), Expect = 2e-05
Identities = 88/335 (26%), Positives = 111/335 (33%), Gaps = 75/335 (22%)
Query: 97 GPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYR 156
GP G G G VLE P + + P PE PA L P G+ P P G G R
Sbjct: 377 GPRGLKGEKGEPAVLE-PGMLVEG-PPGPEGPAGLIGPPGIQGN------PGPVGDPGER 428
Query: 157 EAGGQGG--GAFFSPS-PGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGS 213
G+ G G+ +P PG+S + + F S D+ + AA E +++ +R L
Sbjct: 429 GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAA-QEAQAQAILQQARLALRG 487
Query: 214 P--------LPSPRASP------------RPWTPEDPWSLYGP----------------- 236
P P P P P P P L GP
Sbjct: 488 PPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 547
Query: 237 ---SPGGRGPEDSWLLLSAPGP--------TPASPRPASPCGKR----RYSSSGTPSSAS 281
PG +G L PG P P G+R G P +
Sbjct: 548 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 607
Query: 282 PALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVG-----APPAESIPQKTRRTSSE 336
P RG LG +G P PP D G GP +G PP + T+
Sbjct: 608 P----RGLLGPKGPPGIPGPPGVRGMD-GPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 662
Query: 337 QAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKE 371
Q P E+ LP G S PPG KE
Sbjct: 663 QGAIGPHGEKGPQGKPGLP-GMPGSDGPPGHPGKE 696
Score = 45.4 bits (106), Expect = 2e-04
Identities = 93/361 (25%), Positives = 114/361 (31%), Gaps = 76/361 (21%)
Query: 18 GEEKEAPPLGAGGL-------GEELDSEDAPPCCRLALGEPPPYGA----APIGIPRPPP 66
GE+ GA GL GE D + P R GE P G P GIP PP
Sbjct: 568 GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGP--RGLPGESGPRGLLGPKGPPGIPGPPG 625
Query: 67 PRPGMHSPP-------PRPAPSPGTWESQPARSVRLG-----GPGGGAGGAGGGRVLECP 114
R GM P P+ P P + P G GP G G G + P
Sbjct: 626 VR-GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 684
Query: 115 SIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPP---EGFGGYREAGGQGGGAFFSPSP 171
P E P + N G P YP P +G G R G G P
Sbjct: 685 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFP 744
Query: 172 GSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLP-SPRASPRPWTPEDP 230
G F D V+ + E G P P+ P P
Sbjct: 745 G--------FKGDIG-----------VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 785
Query: 231 WSLYGPS-----------PGGRGPEDSWLLLSAPGPTPASPR--------PASPCGKRRY 271
L G PG +GP+ S L PG AS + P G+R
Sbjct: 786 PGLMGEKGKLGVPGLPGYPGRQGPKGS---LGFPGFPGASGEKGARGLSGKSGPRGERGP 842
Query: 272 SSSGTPSSASPALSRRGSLGEEGSEPPPPPP----LPLARDP-GSPGPFDYVGAPPAESI 326
+ A + G+ G G + P PP LP + P G PGP G P + +
Sbjct: 843 TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 902
Query: 327 P 327
P
Sbjct: 903 P 903
Score = 38.1 bits (87), Expect = 0.037
Identities = 95/387 (24%), Positives = 115/387 (29%), Gaps = 85/387 (21%)
Query: 49 GEPPPYGA-APIGIPRPP-----PPRPGMHSPPPRPAPS--PGTWESQPARSVR--LGGP 98
G P P GA P G P P PG PP P PGT +Q + LG P
Sbjct: 658 GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 717
Query: 99 GG-GAGGAGGGRVLE----------CPSIRIT-----SISPTPEPPAALEDNPDA-WGDG 141
G G G G R L+ P + P + ED P+ G
Sbjct: 718 GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 777
Query: 142 SPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESE 201
P P P G G + G G + G + F AS E
Sbjct: 778 GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS------ 831
Query: 202 LNEAASRFGLGSPLPSPRASPR----------------PWTPEDPWSLYGPS-----PGG 240
++ R G P + PR P P L GP PG
Sbjct: 832 -GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 890
Query: 241 RGPEDSWLLLSAPGPTPASPRPASPCGKR-------RYSSSGTPSSASP--ALSRRGSLG 291
+GP PGP P P G+R + G P P A G +G
Sbjct: 891 KGP---------PGPPGKDGLPGHP-GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 940
Query: 292 EEGSEPPPPPP----LP-------LARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVA 340
E G PP PP LP DPG PG G P + +
Sbjct: 941 ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPG 1000
Query: 341 LPRSEEPASCNGKLPLGAEESVAPPGG 367
L +E P+ G E A GG
Sbjct: 1001 LKGNEGPSGPPGPAGSPGERGAAGSGG 1027
Score = 34.7 bits (78), Expect = 0.41
Identities = 57/204 (27%), Positives = 68/204 (33%), Gaps = 21/204 (10%)
Query: 702 PSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPG 761
P +A G + P PP P P E T G PP P P G
Sbjct: 929 PQGAAGETGPMGERGHPGPPGP--PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA----G 982
Query: 762 LRMFPETRGTTGCAQPPAVSFLPRPF----PSDPYGGRGSSFSLGLPFSPPAPFRPPPLP 817
LR FP RG G A P + P P+ G RG++ S G P PP P P
Sbjct: 983 LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS-GGPIGPPGRPGPQGPP 1041
Query: 818 ASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGIT 877
+ +G + + P +G GP PG P G D P Q T
Sbjct: 1042 GAAGEKGVPGEKGPIGPTGRDGVQ--GPVGLPGPAGPPGVAGEDGDKGEVGD--PGQKGT 1097
Query: 878 LEEVSEIIGRDLSGFPAPPGEEPP 901
E G P PPG P
Sbjct: 1098 KGNKGE------HGPPGPPGPIGP 1115
Score = 32.7 bits (73), Expect = 1.6
Identities = 51/201 (25%), Positives = 58/201 (28%), Gaps = 40/201 (19%)
Query: 702 PSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPG 761
PS G PP PP P P + P G P GP PG
Sbjct: 1163 PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP-------QGPPGGVGNLGP-----PG 1210
Query: 762 LRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPP 821
+ P G+ G P V P G RG G P P P P P
Sbjct: 1211 EKGEPGESGSPGIQGEPGV--------KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGP 1262
Query: 822 LEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEV 881
P P P P PGEG P + G D P Q +
Sbjct: 1263 KGNPGPVGFPGDPGP------------PGEGGPRGQD--GAKGDRGEDGEPGQPGSPGPT 1308
Query: 882 SEIIGRDLSGFPAPPGEEPPA 902
E +G P P G+ PA
Sbjct: 1309 GE------NGPPGPLGKRGPA 1323
Score = 30.4 bits (67), Expect = 7.8
Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 11/96 (11%)
Query: 273 SSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRR 332
S+ T S + A RG GE+G P + + PG GP +G P + P
Sbjct: 365 SAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNP----- 419
Query: 333 TSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGS 368
V P P G LP G++ + PPG S
Sbjct: 420 ----GPVGDPGERGPPGRAG-LP-GSDGAPGPPGTS 449
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 58.9 bits (141), Expect = 2e-08
Identities = 100/393 (25%), Positives = 130/393 (33%), Gaps = 103/393 (26%)
Query: 24 PPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAP----IGIP-----RPPPPRPGMHSP 74
PP G G G+ ED P G P P G +G+P R P PG
Sbjct: 961 PPGGPGDKGDP--GEDGQPGPD---GPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGT 1015
Query: 75 PPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDN 134
P + P+ T + P V GP G G G P PE PA +
Sbjct: 1016 PGKVGPTGATGDKGPPGPV---GPPGSNGPVG---------------EPGPEGPAGNDGT 1057
Query: 135 PD---AWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAAL 191
P A G+ R P P G G + A G G +PG +
Sbjct: 1058 PGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPV---GAPGDAG---------------- 1098
Query: 192 YAACDEVESELNEAASRFGLGSP-LPSPRASPRPWTPEDPWSLYGPS------------- 237
+ + SR +G P R P P P +G
Sbjct: 1099 ---------QRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTG 1149
Query: 238 ----PGGRGPEDSWLLLSAPGP--TPASPRPASPCGKRRYSSSGTPSSASPA--LSRRGS 289
PG GP PGP P P P GK G P P RGS
Sbjct: 1150 LQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKE-----GNPGPLGPIGPPGVRGS 1204
Query: 290 LGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPA-------ESIPQKTRRTSSEQAVALP 342
+GE G E PP P P PG PGP ++ A ES+P + +QA
Sbjct: 1205 VGEAGPEGPPGEPGP----PGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDD 1260
Query: 343 RSEEPASCNGKL-PLGAE-ESVAPPGGSRKEVA 373
+++ + L L ++ E++ P GS+K A
Sbjct: 1261 KNKTDPGVHATLKSLSSQIETMRSPDGSKKHPA 1293
Score = 57.8 bits (138), Expect = 5e-08
Identities = 91/320 (28%), Positives = 108/320 (33%), Gaps = 52/320 (16%)
Query: 24 PPLGAGGLGEELDSED----APPCCRL---ALGEPPPYGAAPIGIPRPPPPRPGMHSPPP 76
PP AG GE+ + PP R + GE P GA P+ P +PG+ P
Sbjct: 805 PPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPG 864
Query: 77 RPAPSPGTWESQPARSVRLGGPGG--GAGGAGGGRVLECP---------SIRITSISPTP 125
P P GP G G G GGR + P + R+ P
Sbjct: 865 EPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAG 924
Query: 126 EP-PAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSD 184
P PA P G R P G G R G GG PG
Sbjct: 925 APGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDG-------QP 977
Query: 185 ASDEAALYAACDEVESELNEAASRFGLGSP-LPSPRASPRPWTPEDPWSLYGPSPGGRGP 243
D A + R G P LP P +P P GP PG GP
Sbjct: 978 GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGP-PGPVGP 1036
Query: 244 EDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSE-PPPPPP 302
S GP P P P G + GTP R G++GE G P P
Sbjct: 1037 PGS------NGPV-GEPGPEGPAG-----NDGTP-------GRDGAVGERGDRGDPGPAG 1077
Query: 303 LPLARD-PGSPGPFDYVGAP 321
LP ++ PG+PGP VGAP
Sbjct: 1078 LPGSQGAPGTPGP---VGAP 1094
Score = 50.1 bits (118), Expect = 9e-06
Identities = 96/370 (25%), Positives = 117/370 (31%), Gaps = 81/370 (21%)
Query: 49 GEPPPYGAAPIGI--PRPPPPRPGMHSPPPRPA-PSPGTWESQPARSVRLGGPG-GGAGG 104
G+P P G PIG P PP +PG P R P + P G PG G G
Sbjct: 243 GDPGPMG--PIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKG 300
Query: 105 AGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGG 164
G + LE P + +P + A A G PR P G G + A GQ G
Sbjct: 301 HRGHKGLEGPKGEVG--APGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGA 358
Query: 165 AFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRP 224
PG PL P +S P
Sbjct: 359 HGMPGKPGPM--------------------------------------GPLGIPGSSGFP 380
Query: 225 WTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPAL 284
P GP+ G RGPE GP P P + GTP + P
Sbjct: 381 GNPGMKGEA-GPT-GARGPEGPQGQRGETGPPGPVGSPGLP---GAIGTDGTPGAKGPTG 435
Query: 285 SRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRS 344
S G+ G GS PP P P GS GP G P +P + A P+
Sbjct: 436 S-PGTSGPPGSAGPPGSPGP----QGSTGPQGIRGQPGDPGVP-------GFKGEAGPKG 483
Query: 345 EE-PASCNGKL----------PLGAEESVAPPG--GSR-----KEVAGMDYLAVPSPLAW 386
E P G + P G +V PPG G R + G D L P
Sbjct: 484 EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQG 543
Query: 387 SKARIGGHSP 396
+ +G P
Sbjct: 544 ERGPVGSSGP 553
Score = 48.5 bits (114), Expect = 3e-05
Identities = 100/388 (25%), Positives = 125/388 (32%), Gaps = 60/388 (15%)
Query: 18 GEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPR 77
G + EA P G G L P GE G P+ P + G H P +
Sbjct: 318 GSKGEAGPTGPMGAMGPLGPRGMP-------GERGRLG------PQGAPGQRGAHGMPGK 364
Query: 78 PAPSPGTWESQPARSVRLGGPG-GGAGGAGGGRVLECPSIRITSISP-----TPEPPAAL 131
P P P S G PG G G G R E P + P +P P A+
Sbjct: 365 PGPMGPL--GIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAI 422
Query: 132 --EDNPDAWGD-GSPRDYPPPEGFGGYREAGGQG--GGAFFSPSPGSSSLSSWSFFSDAS 186
+ P A G GSP PP G G QG G PG + + +
Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482
Query: 187 DEAALYAACDEV-----ESELNEAASRFGLGSPLP-SPRASP--RPWTPEDPWSLYGP-- 236
E + + E + +G P P R +P R + D L GP
Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSD--GLPGPKG 540
Query: 237 SPGGRGPEDSWLLLSAPGPTPASP-RPASPCGKRRYSSSGTPSSASPA--LSRRGSLGEE 293
+ G RGP S S P + P RP P +G P P L G+ GE+
Sbjct: 541 AQGERGPVGS----SGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGED 596
Query: 294 GSEPPP--------------PPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAV 339
G PP P P + DPG PG G P P K V
Sbjct: 597 GRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPV 656
Query: 340 ALP-RSEEPASCNGKLPLGAEESVAPPG 366
P + E P G + PPG
Sbjct: 657 GPPGLAGERGEQGPPGPTGFQGLPGPPG 684
Score = 43.9 bits (102), Expect = 7e-04
Identities = 88/348 (25%), Positives = 111/348 (31%), Gaps = 81/348 (23%)
Query: 49 GEPPPYGAAPIGIPRPP--PPRPGM--------------------HSPPPRPAPSPGT-- 84
G+P P G P+GIP P PGM + PP P SPG
Sbjct: 363 GKPGPMG--PLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPG 420
Query: 85 --------WESQPARSVRLGGPGGGAG--GAGGGRVLECPSIRITSISPTPEPPAALEDN 134
P S GP G AG G+ G + P I P P
Sbjct: 421 AIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQ----GIRGQPGDPGV---- 472
Query: 135 PDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAA 194
P G+ P+ P P G G G+ G PG+ A +
Sbjct: 473 PGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRG-FPG 531
Query: 195 CDEVESELNEAASRFGLGS--PLPSPRASPRPWTPEDPWS--LYGPSPGGRGPEDSWLLL 250
D + R +GS P S RP P P + L G +PG +GPE L
Sbjct: 532 SDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTG-NPGVQGPEGKLGPL 590
Query: 251 SAPGPTPASPRPASPCGKRRYSSSGTP----SSASPAL----------SRRGSLGEEGSE 296
APG P S + + S G P SS P +RG+ G++G
Sbjct: 591 GAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEV 650
Query: 297 PP-----------------PPPPLPLARDPGSPGPFDYVGAPPAESIP 327
P PP P PG PGP G P + +P
Sbjct: 651 GPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVP 698
Score = 42.4 bits (98), Expect = 0.002
Identities = 89/345 (25%), Positives = 111/345 (32%), Gaps = 50/345 (14%)
Query: 49 GEPPPYGAAPIGIPRPP--PPRPGMHSPPPRPA-PSPG----TWESQPARSVRLGGPGG- 100
G P P G P GI P P +PG PP P+ P P + +Q A G G
Sbjct: 150 GRPGPRG--PQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQ 207
Query: 101 -----GAGGAGGGRVLECPSIRITSISPTPEPPAALEDNP-DAWGDGSPRDYPPPEGFGG 154
G+ G G R + + PT P + P G P P G G
Sbjct: 208 VGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDG 267
Query: 155 YREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAAL--YAACDEVESELNEAASRFGLG 212
G G F+ SPG+ F A L + +E E +
Sbjct: 268 EPGRNGNPGEVGFAGSPGARG------FPGAPGLPGLKGHRGHKGLEGPKGEVGA----- 316
Query: 213 SPLPSPRASPRPWTPEDPWSLYGP--SPGGR---GPEDSWLLLSAPGPTPASPRPASPCG 267
P + P P GP PG R GP+ + A G P P P P G
Sbjct: 317 ---PGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHG-MPGKPGPMGPLG 372
Query: 268 KRRYSSSGTPSS------ASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAP 321
SSG P + A P RG G +G PP P+ PG PG G P
Sbjct: 373 IP--GSSGFPGNPGMKGEAGPT-GARGPEGPQGQRGETGPPGPVG-SPGLPGAIGTDGTP 428
Query: 322 PAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPG 366
A+ + + P S P G P G PG
Sbjct: 429 GAKGPTGSPGTSGPPGSAGPPGSPGPQGSTG--PQGIRGQPGDPG 471
Score = 38.5 bits (88), Expect = 0.028
Identities = 86/353 (24%), Positives = 112/353 (31%), Gaps = 62/353 (17%)
Query: 18 GEEKEAPPLGAGG-LGEELD----SEDAPPCCRLALGEPPPYGA----APIGIP----RP 64
G + E P+G+ G G + D E P R G P G P+G P RP
Sbjct: 540 GAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRP 599
Query: 65 PPPRP-GMHSPP-----PRPAPSPGTWESQPARSVRLGGPGG-GAGGAGGGRVLECPSIR 117
PP G+ P P P S G +P + G PG GA G G
Sbjct: 600 GPPGSIGIRGQPGSMGLPGPKGSSGD-PGKPGEAGNAGVPGQRGAPGKDG---------- 648
Query: 118 ITSISPT-PEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSL 176
+ P+ P P L G P + +G G G+GG PG +
Sbjct: 649 --EVGPSGPVGPPGLAGERGEQGPPGPTGF---QGLPGPPGPPGEGG------KPGDQGV 697
Query: 177 SSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGP 236
D A+ E G+ + LP + P+ P GP
Sbjct: 698 PG--------DPGAVGPLGPRGERGNPGERGEPGI-TGLPGEKGMAGGHGPDGPKGSPGP 748
Query: 237 S--PGGRGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEG 294
S PG GP L PG + P + G +A G+ G G
Sbjct: 749 SGTPGDTGPPG---LQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAG----NDGARGLPG 801
Query: 295 SEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEP 347
PP P P + G PGP VG P + P AV + P
Sbjct: 802 PLGPPGPAGPTG-EKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGP 853
Score = 37.0 bits (84), Expect = 0.083
Identities = 38/122 (31%), Positives = 47/122 (38%), Gaps = 17/122 (13%)
Query: 218 PRASPRPWTPE--DPWSLYGPSPGGRGPEDSWLLLSAPGPTPAS-PRPASPCGKRRYSSS 274
P+ P P P+ D PG GP S PGP S P A G S
Sbjct: 148 PKGRPGPRGPQGIDGEPGVPGQPGAPGPPGH---PSHPGPDGLSRPFSAQMAGLDEKSGL 204
Query: 275 GT-----PSSASPALSR--RGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIP 327
G+ P S P R +G G++G P PP +PG PGP +G+ E P
Sbjct: 205 GSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPP----GEPGDPGPMGPIGSRGPEGPP 260
Query: 328 QK 329
K
Sbjct: 261 GK 262
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 58.5 bits (140), Expect = 3e-08
Identities = 93/364 (25%), Positives = 112/364 (30%), Gaps = 91/364 (25%)
Query: 67 PRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPE 126
P P S SPG + + + R GP GGGRV E P R S+ P
Sbjct: 301 PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGP---EHSKGGGRVDEGPQPR--SVEPQDA 355
Query: 127 PPAALEDNPDAWGDGSPRDYP------------------PPEGFG--------------- 153
P +A G G R P PP G
Sbjct: 356 GPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLE 415
Query: 154 -----------GYREAGGQGGGAFFSP--SPGSSSLSSWSFFSDASDEAALYAACDEVES 200
G +E GGQ G P P + ++ DE A D
Sbjct: 416 GCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGA----GDSAAV 471
Query: 201 ELNEAASRFGLGSPLPSP-----------------RASPRPWTPEDPWSLYGPSPGG-RG 242
A + GSP PS R P+ TP P GPSP G G
Sbjct: 472 ASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAG 531
Query: 243 PEDSWLLLSAPGPTPASP---------------RPASPCGKRRYSSSGTPSSASPALSRR 287
E + PGP PA P RPA P G S SPA R
Sbjct: 532 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTR 591
Query: 288 GSLGEEGSEPPPPPPLPLARDPGSPGPFDYVG---APPAESIPQKTRRTSSEQAVALPRS 344
E SE P P P A D + P + G A PA P ++ + + A P
Sbjct: 592 DEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTR 651
Query: 345 EEPA 348
+EPA
Sbjct: 652 DEPA 655
Score = 40.4 bits (93), Expect = 0.007
Identities = 63/230 (27%), Positives = 72/230 (31%), Gaps = 57/230 (24%)
Query: 91 RSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDN-----------PDAWG 139
R V G A +GG + L S +P+ P A +N P
Sbjct: 459 RKVDEGAGDSAAVASGGAQTLALAG----SPAPSGHPKAGHSENGVEEDTEGRTGPKEGT 514
Query: 140 DGSPRDYPPPEGFG--------------GYREAGGQGGGAFFSPS--PGSSSLSSWSFFS 183
GSP + P P G G R AG G SPS PG
Sbjct: 515 PGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGP----- 569
Query: 184 DASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG-RG 242
A DE A E SE +P PSP R E P GP P G G
Sbjct: 570 -AGDEPA------ESPSE-----------TPGPSPAGPTRDEPAESPSETPGPRPAGPAG 611
Query: 243 PEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGE 292
E + PGP PA P P S + PS A P GE
Sbjct: 612 DEPAESPSETPGPRPAGPAGDEPA--ESPSETPGPSPAGPTRDEPAKAGE 659
Score = 36.6 bits (83), Expect = 0.11
Identities = 45/169 (26%), Positives = 59/169 (34%), Gaps = 26/169 (15%)
Query: 51 PPPYGAA-------PIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAG 103
P P G A P P P P P P P+ +PG + PA P G
Sbjct: 524 PSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPG 583
Query: 104 GAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGG 163
+ G + P+ S +P P P D P SP + P P R AG G
Sbjct: 584 PSPAGPTRDEPA-ESPSETPGPRPAGPAGDEPAE----SPSETPGP------RPAGPAGD 632
Query: 164 GAFFSPS--PGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFG 210
SPS PG S DE A E++ E++++ G
Sbjct: 633 EPAESPSETPGPSPA------GPTRDEPAKAGEAAELQDAEVESSAKSG 675
Score = 35.0 bits (79), Expect = 0.31
Identities = 51/206 (24%), Positives = 66/206 (32%), Gaps = 42/206 (20%)
Query: 700 GFPSASATPFGTDMDF---SPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPP 756
G P A + G + D + P+ P P E P G P P G P
Sbjct: 489 GHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETP-------------GPSPAGP-AGDEP 534
Query: 757 SYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPL 816
+ P P G G + S P P P+ P G P P+ P P
Sbjct: 535 AESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDE--------PAESPSE-TPGPS 585
Query: 817 PASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGI 876
PA P + P S S+ PG P A ++ + G R + P
Sbjct: 586 PAGPTRDEPAESPSET------------PGPRPAGPAGDEPAESPSETPGPRPAGPAGDE 633
Query: 877 TLEEVSEIIGRDLSGFPAPPGEEPPA 902
E SE G PA P + PA
Sbjct: 634 PAESPSETPGPS----PAGPTRDEPA 655
Score = 33.1 bits (74), Expect = 1.2
Identities = 48/198 (24%), Positives = 71/198 (35%), Gaps = 22/198 (11%)
Query: 213 SPLPSPRASPR-------PWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASP 265
S LP P R P P+ S G + G + + P P P+ A P
Sbjct: 298 SSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGP 357
Query: 266 CGKRRYSSSG-----TPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGA 320
+ + +G P SP S++ L E PP P P + + G
Sbjct: 358 LERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGC 417
Query: 321 PPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEV--AGMDYL 378
++ Q + RT +++ E C + PLGA VA R++V D
Sbjct: 418 ----ALSQGSLRTGTQEVGGQDPGEAVQPC--RQPLGAR--VADKVRKRRKVDEGAGDSA 469
Query: 379 AVPSPLAWSKARIGGHSP 396
AV S A + A G +P
Sbjct: 470 AVASGGAQTLALAGSPAP 487
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.135 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,592,605
Number of Sequences: 37866
Number of extensions: 4243053
Number of successful extensions: 48265
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 458
Number of HSP's successfully gapped in prelim test: 1895
Number of HSP's that attempted gapping in prelim test: 21280
Number of HSP's gapped (non-prelim): 18580
length of query: 902
length of database: 18,247,518
effective HSP length: 111
effective length of query: 791
effective length of database: 14,044,392
effective search space: 11109114072
effective search space used: 11109114072
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.