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Search of human proteins with 27883842
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens]
(326 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens] 671 0.0
gi|6005964 ring finger protein 110 [Homo sapiens] 420 e-117
gi|109240538 polycomb group ring finger 1 [Homo sapiens] 170 1e-42
gi|31742478 ring finger protein 3 [Homo sapiens] 155 6e-38
gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens] 144 8e-35
gi|33300663 polycomb group ring finger 5 [Homo sapiens] 138 6e-33
gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens] 89 4e-18
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 52 5e-07
gi|6005747 ring finger protein 2 [Homo sapiens] 48 1e-05
gi|197245452 ring finger protein 24 isoform 2 [Homo sapiens] 48 1e-05
gi|197245450 ring finger protein 24 isoform 1 [Homo sapiens] 48 1e-05
gi|6857791 ring finger protein 24 isoform 1 [Homo sapiens] 48 1e-05
gi|51479192 ring finger protein 1 [Homo sapiens] 47 2e-05
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H... 47 3e-05
gi|30425428 deltex homolog 3 [Homo sapiens] 46 4e-05
gi|14550405 postreplication repair protein hRAD18p [Homo sapiens] 45 9e-05
gi|239048909 checkpoint with forkhead and ring finger domains is... 44 1e-04
gi|239048905 checkpoint with forkhead and ring finger domains is... 44 1e-04
gi|239048862 checkpoint with forkhead and ring finger domains is... 44 1e-04
gi|239048792 checkpoint with forkhead and ring finger domains is... 44 1e-04
gi|239048907 checkpoint with forkhead and ring finger domains is... 44 1e-04
gi|73747840 LON peptidase N-terminal domain and ring finger 3 is... 43 3e-04
gi|37622896 LON peptidase N-terminal domain and ring finger 3 is... 43 3e-04
gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens] 43 3e-04
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 42 7e-04
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 42 7e-04
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 42 7e-04
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi... 42 7e-04
gi|239755486 PREDICTED: tripartite motif-containing protein 64C-... 42 0.001
gi|239755484 PREDICTED: tripartite motif-containing protein 64C-... 42 0.001
>gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens]
Length = 326
Score = 671 bits (1731), Expect = 0.0
Identities = 326/326 (100%), Positives = 326/326 (100%)
Query: 1 MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQV 60
MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQV
Sbjct: 1 MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQV 60
Query: 61 HKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADE 120
HKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADE
Sbjct: 61 HKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADE 120
Query: 121 DKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLR 180
DKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLR
Sbjct: 121 DKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLR 180
Query: 181 SKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQR 240
SKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQR
Sbjct: 181 SKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQR 240
Query: 241 DGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSP 300
DGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSP
Sbjct: 241 DGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSP 300
Query: 301 SGNHQSSFANRPRKSSVNGSSATSSG 326
SGNHQSSFANRPRKSSVNGSSATSSG
Sbjct: 301 SGNHQSSFANRPRKSSVNGSSATSSG 326
>gi|6005964 ring finger protein 110 [Homo sapiens]
Length = 344
Score = 420 bits (1079), Expect = e-117
Identities = 210/339 (61%), Positives = 260/339 (76%), Gaps = 20/339 (5%)
Query: 1 MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQV 60
MHRTTRIKITELNPHLMC LCGGYFIDATTI+ECLHSFCKTCIVRYLET+KYCP+CDVQV
Sbjct: 1 MHRTTRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQV 60
Query: 61 HKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADE 120
HKTRPLL+IRSDKTLQDIVYKLVPGLFK+EMKRRRDFYAA+P + NGSNEDRGEV ++
Sbjct: 61 HKTRPLLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQ 120
Query: 121 DKRIITDDEIISLSIEFFD--QNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKF 178
+K ++DDEI+SLSIEF++ ++R ++K + +E R+LRCPAAMTVMHL KF
Sbjct: 121 EKGALSDDEIVSLSIEFYEGARDRDEKKGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKF 180
Query: 179 LRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKIS- 237
LR+KMD+P+ ++++V+YE+EPLK+YYTLMDIAYIY WRRNGPLPLKYRV+P CKR+ ++
Sbjct: 181 LRNKMDVPSKYKVEVLYEDEPLKEYYTLMDIAYIYPWRRNGPLPLKYRVQPACKRLTLAT 240
Query: 238 --HQRDGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQ---------SPHPQF 286
+G +G E +S SDKA SPA +P+TSS LPSP+TP + HP
Sbjct: 241 VPTPSEGTNTSGASECESVSDKAPSPA-TLPATSSSLPSPATPSHGSPSSHGPPATHPTS 299
Query: 287 PHISSTMNGTSNSPSGN-----HQSSFANRPRKSSVNGS 320
P ST +G + + +G S +R RK +VNG+
Sbjct: 300 PTPPSTASGATTAANGGSLNCLQTPSSTSRGRKMTVNGA 338
>gi|109240538 polycomb group ring finger 1 [Homo sapiens]
Length = 259
Score = 170 bits (431), Expect = 1e-42
Identities = 87/224 (38%), Positives = 141/224 (62%), Gaps = 4/224 (1%)
Query: 6 RIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRP 65
R+KI +LN H++C LC GYF+DATTI ECLH+FCK+CIV+YL+TSKYCP+C++++H+T+P
Sbjct: 35 RVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQP 94
Query: 66 LLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRII 125
LLN++ D+ +QDIVYKLVPGL +E KR R+FY + D + +++
Sbjct: 95 LLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSR-GLDRVTQPTGEEPALSNLGLPFS 153
Query: 126 TDDEIISLSIEFFDQ-NRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMD 184
+ D + + +Q N +++ K+K+K + +K Y+RC V HLR+ L ++
Sbjct: 154 SFDHSKAHYYRYDEQLNLCLERLSSGKDKNKSVLQNK-YVRCSVRAEVRHLRRVLCHRLM 212
Query: 185 IPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVR 228
+ N + ++++ E L D+ T+ I + + PL L+Y V+
Sbjct: 213 L-NPQHVQLLFDNEVLPDHMTMKQIWLSRWFGKPSPLLLQYSVK 255
>gi|31742478 ring finger protein 3 [Homo sapiens]
Length = 242
Score = 155 bits (391), Expect = 6e-38
Identities = 87/249 (34%), Positives = 139/249 (55%), Gaps = 41/249 (16%)
Query: 4 TTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKT 63
T +IK+ ++N H+ C LC GY IDATT+ ECLH+FC++C+V+YLE + CP C + +H++
Sbjct: 3 TRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQS 62
Query: 64 RPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFY----------------------AAH 101
PL I D+T+QDIVYKLVPGL + EM+++R+FY +H
Sbjct: 63 HPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGETCSAKQHLDSH 122
Query: 102 PSAD--AANGSNEDRG-EVADEDKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEV 158
+ + A + SN++ E +ED DE +S+ +E SK
Sbjct: 123 RNGETKADDSSNKEAAEEKPEEDNDYHRSDEQVSICLEC--------------NSSKLRG 168
Query: 159 NDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWR-R 217
++++RC A TV+HL+KF+ K+++ + ++D++ EE L +TL + + WR +
Sbjct: 169 LKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVV-VTRWRFK 227
Query: 218 NGPLPLKYR 226
PL L YR
Sbjct: 228 KAPLLLHYR 236
>gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens]
Length = 350
Score = 144 bits (364), Expect = 8e-35
Identities = 80/209 (38%), Positives = 118/209 (56%), Gaps = 15/209 (7%)
Query: 7 IKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPL 66
I ++EL P+++C +C GY IDATTI ECLH+FCK+CIVR+ S CP C++ VH+T+PL
Sbjct: 123 INLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPL 182
Query: 67 LNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFY------AAHPSADAANGSNEDRGEVADE 120
NIR D+ LQDIVYKLV L + E K+ DFY P+ S++ R + E
Sbjct: 183 YNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPSSKGRSKKVLE 242
Query: 121 DKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLR 180
I + +SL +EF N + + +K+++R T+ H+ KFLR
Sbjct: 243 SVFRIPPELDMSLLLEFIGAN---------EGTGHFKPLEKKFVRVSGEATIGHVEKFLR 293
Query: 181 SKMDIPNTFQIDVMYEEEPLKDYYTLMDI 209
KM + Q+D++ + L+ Y TL +I
Sbjct: 294 RKMGLDPACQVDIICGDHLLEQYQTLREI 322
>gi|33300663 polycomb group ring finger 5 [Homo sapiens]
Length = 256
Score = 138 bits (348), Expect = 6e-33
Identities = 73/222 (32%), Positives = 125/222 (56%), Gaps = 22/222 (9%)
Query: 9 ITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLN 68
+ + NP++ C +C GY I TT+ ECLH+FCKTCIV++ E S CP C QVH+T PL
Sbjct: 9 VKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEM 68
Query: 69 IRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAH--------PSADAANGSNEDRGEVADE 120
+R D TL++I++KLVPGL + E++R +F+ + ++ A ++ G+ ++
Sbjct: 69 LRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKADKPKVDEEGDENED 128
Query: 121 DKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVND---KRYLRCPAAMTVMHLRK 177
DK D I++ ++ N +S + V K+++RC +TV ++K
Sbjct: 129 DKDYHRSDPQIAICLDCLRNN----------GQSGDNVVKGLMKKFIRCSTRVTVGTIKK 178
Query: 178 FLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNG 219
FL K+ +P+++++DV+ E + +T M+ Y+ WR G
Sbjct: 179 FLSLKLKLPSSYELDVLCNGEIMGKDHT-MEFIYMTRWRLRG 219
>gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens]
Length = 275
Score = 89.4 bits (220), Expect = 4e-18
Identities = 36/67 (53%), Positives = 52/67 (77%)
Query: 7 IKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPL 66
I ++EL P+++C +C GY IDATTI ECLH+FCK+CIVR+ S CP C++ VH+T+PL
Sbjct: 123 INLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPL 182
Query: 67 LNIRSDK 73
NI +++
Sbjct: 183 YNISANE 189
Score = 39.7 bits (91), Expect = 0.004
Identities = 17/50 (34%), Positives = 30/50 (60%)
Query: 160 DKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDI 209
+K+++R T+ H+ KFLR KM + Q+D++ + L+ Y TL +I
Sbjct: 198 EKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLEQYQTLREI 247
>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
Length = 485
Score = 52.4 bits (124), Expect = 5e-07
Identities = 31/85 (36%), Positives = 45/85 (52%), Gaps = 10/85 (11%)
Query: 12 LNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQV-HKTRPLLNIR 70
L L C++C YFI+A T+ C HSFC CI +++ CPIC + KT L+
Sbjct: 397 LENELQCIICSEYFIEAVTL-NCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLV--- 452
Query: 71 SDKTLQDIVYKLVPGLFKNEMKRRR 95
L + + K+V L +E+K RR
Sbjct: 453 ----LDNCINKMVNNL-SSEVKERR 472
>gi|6005747 ring finger protein 2 [Homo sapiens]
Length = 336
Score = 47.8 bits (112), Expect = 1e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 13/91 (14%)
Query: 12 LNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLET-SKYCPICDVQVHKTRPLLNIR 70
L+ LMC +C + T ECLH FC CI+ L + +K CP C ++ R ++R
Sbjct: 45 LHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKR---SLR 101
Query: 71 SDKTLQDIVYKLVPGLFKNEMKRRRDFYAAH 101
D ++ K+ P RD Y AH
Sbjct: 102 PDPNFDALISKIYPS---------RDEYEAH 123
>gi|197245452 ring finger protein 24 isoform 2 [Homo sapiens]
Length = 169
Score = 47.8 bits (112), Expect = 1e-05
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Query: 8 KITELNPHLMCVLCGGYFI--DATTIIECLHSFCKTCIVRYLETSKYCPICDVQV 60
K+ ELN H +C +C F D I C H+F + C++++LE K CP+C++ V
Sbjct: 89 KVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPV 143
>gi|197245450 ring finger protein 24 isoform 1 [Homo sapiens]
Length = 148
Score = 47.8 bits (112), Expect = 1e-05
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Query: 8 KITELNPHLMCVLCGGYFI--DATTIIECLHSFCKTCIVRYLETSKYCPICDVQV 60
K+ ELN H +C +C F D I C H+F + C++++LE K CP+C++ V
Sbjct: 68 KVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPV 122
>gi|6857791 ring finger protein 24 isoform 1 [Homo sapiens]
Length = 148
Score = 47.8 bits (112), Expect = 1e-05
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Query: 8 KITELNPHLMCVLCGGYFI--DATTIIECLHSFCKTCIVRYLETSKYCPICDVQV 60
K+ ELN H +C +C F D I C H+F + C++++LE K CP+C++ V
Sbjct: 68 KVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPV 122
>gi|51479192 ring finger protein 1 [Homo sapiens]
Length = 406
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 13/91 (14%)
Query: 12 LNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLET-SKYCPICDVQVHKTRPLLNIR 70
L+ LMC +C + T ECLH FC CIV L + +K CP C ++ R ++R
Sbjct: 42 LHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKR---SLR 98
Query: 71 SDKTLQDIVYKLVPGLFKNEMKRRRDFYAAH 101
D ++ K+ P R+ Y AH
Sbjct: 99 PDPNFDALISKIYPS---------REEYEAH 120
>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
sapiens]
Length = 773
Score = 46.6 bits (109), Expect = 3e-05
Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 18 CVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQD 77
C LC F + T C HSFCK C+ R L+ + YCP+C + + + L++
Sbjct: 479 CSLCMRLFFEPVTT-PCGHSFCKNCLERCLDHAPYCPLCKESLKEYLADRRYCVTQLLEE 537
Query: 78 IVYKLVPGLFKNEMKRRRDFY 98
++ K +P +E+ R+ Y
Sbjct: 538 LIVKYLP----DELSERKKIY 554
Score = 30.8 bits (68), Expect = 1.7
Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Query: 16 LMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPIC 56
L C+ C G+ + T+ C HS+C+ C+ R L C +C
Sbjct: 121 LRCLGCRGFLSEPVTV-PCGHSYCRRCLRRELRAR--CRLC 158
>gi|30425428 deltex homolog 3 [Homo sapiens]
Length = 347
Score = 46.2 bits (108), Expect = 4e-05
Identities = 18/39 (46%), Positives = 25/39 (64%)
Query: 18 CVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPIC 56
C +C G +A T+ +C HSFC+ CI R L+ K CP+C
Sbjct: 164 CPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMC 202
>gi|14550405 postreplication repair protein hRAD18p [Homo sapiens]
Length = 495
Score = 45.1 bits (105), Expect = 9e-05
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 4/67 (5%)
Query: 16 LMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTL 75
L C +C YF A I +C H++C CI ++L CP C V V T P ++++++ L
Sbjct: 23 LRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTV--TEP--DLKNNRIL 78
Query: 76 QDIVYKL 82
++V L
Sbjct: 79 DELVKSL 85
>gi|239048909 checkpoint with forkhead and ring finger domains
isoform 5 [Homo sapiens]
Length = 572
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 26/131 (19%)
Query: 8 KITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVH---KTR 64
K ++ L C++C D ++ C+H+FC C ++E S CP C V K
Sbjct: 202 KPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNH 261
Query: 65 PLLNI------------RSDKTLQ--DIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGS 110
L N+ RS++ +Q D K+ + + +++R S GS
Sbjct: 262 ILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRR---------SFSDEEGS 312
Query: 111 NEDRGEVADED 121
+ED E++D D
Sbjct: 313 SEDLLELSDVD 323
>gi|239048905 checkpoint with forkhead and ring finger domains
isoform 3 [Homo sapiens]
Length = 652
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 26/131 (19%)
Query: 8 KITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVH---KTR 64
K ++ L C++C D ++ C+H+FC C ++E S CP C V K
Sbjct: 282 KPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNH 341
Query: 65 PLLNI------------RSDKTLQ--DIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGS 110
L N+ RS++ +Q D K+ + + +++R S GS
Sbjct: 342 ILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRR---------SFSDEEGS 392
Query: 111 NEDRGEVADED 121
+ED E++D D
Sbjct: 393 SEDLLELSDVD 403
>gi|239048862 checkpoint with forkhead and ring finger domains
isoform 2 [Homo sapiens]
Length = 663
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 26/131 (19%)
Query: 8 KITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVH---KTR 64
K ++ L C++C D ++ C+H+FC C ++E S CP C V K
Sbjct: 294 KPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNH 353
Query: 65 PLLNI------------RSDKTLQ--DIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGS 110
L N+ RS++ +Q D K+ + + +++R S GS
Sbjct: 354 ILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRR---------SFSDEEGS 404
Query: 111 NEDRGEVADED 121
+ED E++D D
Sbjct: 405 SEDLLELSDVD 415
>gi|239048792 checkpoint with forkhead and ring finger domains
isoform 1 [Homo sapiens]
Length = 664
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 26/131 (19%)
Query: 8 KITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVH---KTR 64
K ++ L C++C D ++ C+H+FC C ++E S CP C V K
Sbjct: 294 KPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNH 353
Query: 65 PLLNI------------RSDKTLQ--DIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGS 110
L N+ RS++ +Q D K+ + + +++R S GS
Sbjct: 354 ILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRR---------SFSDEEGS 404
Query: 111 NEDRGEVADED 121
+ED E++D D
Sbjct: 405 SEDLLELSDVD 415
>gi|239048907 checkpoint with forkhead and ring finger domains
isoform 4 [Homo sapiens]
Length = 623
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 26/131 (19%)
Query: 8 KITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVH---KTR 64
K ++ L C++C D ++ C+H+FC C ++E S CP C V K
Sbjct: 253 KPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNH 312
Query: 65 PLLNI------------RSDKTLQ--DIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGS 110
L N+ RS++ +Q D K+ + + +++R S GS
Sbjct: 313 ILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRR---------SFSDEEGS 363
Query: 111 NEDRGEVADED 121
+ED E++D D
Sbjct: 364 SEDLLELSDVD 374
>gi|73747840 LON peptidase N-terminal domain and ring finger 3
isoform 1 [Homo sapiens]
Length = 759
Score = 43.1 bits (100), Expect = 3e-04
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 5/83 (6%)
Query: 16 LMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTL 75
L C LC F + T C H+FC C+ R L+ + CP+C + + + +
Sbjct: 465 LECALCMRLFYEPVTT-PCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIM 523
Query: 76 QDIVYKLVPGLFKNEMKRRRDFY 98
++++ K +P E+K RR Y
Sbjct: 524 EELIAKFLP----EELKERRKLY 542
Score = 36.2 bits (82), Expect = 0.041
Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 10 TELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQV 60
TE+ C C G+ D ++ C H+FCK C+ R + C +C V++
Sbjct: 150 TEVWDGFKCRKCHGFLSDPVSL-SCGHTFCKLCLERGRAADRRCALCGVKL 199
>gi|37622896 LON peptidase N-terminal domain and ring finger 3
isoform 2 [Homo sapiens]
Length = 718
Score = 43.1 bits (100), Expect = 3e-04
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 5/83 (6%)
Query: 16 LMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTL 75
L C LC F + T C H+FC C+ R L+ + CP+C + + + +
Sbjct: 424 LECALCMRLFYEPVTT-PCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIM 482
Query: 76 QDIVYKLVPGLFKNEMKRRRDFY 98
++++ K +P E+K RR Y
Sbjct: 483 EELIAKFLP----EELKERRKLY 501
Score = 36.2 bits (82), Expect = 0.041
Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 10 TELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQV 60
TE+ C C G+ D ++ C H+FCK C+ R + C +C V++
Sbjct: 150 TEVWDGFKCRKCHGFLSDPVSL-SCGHTFCKLCLERGRAADRRCALCGVKL 199
>gi|94536782 tripartite motif-containing 35 isoform 2 [Homo
sapiens]
Length = 493
Score = 43.1 bits (100), Expect = 3e-04
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 7/70 (10%)
Query: 16 LMCVLCGGYFIDATTIIECLHSFCKTCIVR--YLETSKYCPICDVQVHKTRPLLNIRSDK 73
L+C +C F DA T+ C H+FC+ C+ R ++ S CP+C + ++R++
Sbjct: 19 LLCAVCYDPFRDAVTL-RCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPA----DLRTNH 73
Query: 74 TLQDIVYKLV 83
TL ++V KL+
Sbjct: 74 TLNNLVEKLL 83
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo
sapiens]
Length = 488
Score = 42.0 bits (97), Expect = 7e-04
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 8/79 (10%)
Query: 4 TTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRY---LETSKYCPICDVQV 60
+T + L C +C Y + IIEC H+FCK CI R+ LE CP+C
Sbjct: 15 STAAALENLQVEASCSVCLEY-LKEPVIIECGHNFCKACITRWWEDLERDFPCPVC---- 69
Query: 61 HKTRPLLNIRSDKTLQDIV 79
KT ++R ++ L +V
Sbjct: 70 RKTSRYRSLRPNRQLGSMV 88
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo
sapiens]
Length = 518
Score = 42.0 bits (97), Expect = 7e-04
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 8/79 (10%)
Query: 4 TTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRY---LETSKYCPICDVQV 60
+T + L C +C Y + IIEC H+FCK CI R+ LE CP+C
Sbjct: 15 STAAALENLQVEASCSVCLEY-LKEPVIIECGHNFCKACITRWWEDLERDFPCPVC---- 69
Query: 61 HKTRPLLNIRSDKTLQDIV 79
KT ++R ++ L +V
Sbjct: 70 RKTSRYRSLRPNRQLGSMV 88
>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
sapiens]
Length = 481
Score = 42.0 bits (97), Expect = 7e-04
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 8/55 (14%)
Query: 9 ITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRY-------LETSKYCPIC 56
+T L + C +C G + TI +C H+FC+ C+ RY LE S CP+C
Sbjct: 7 VTSLADEVNCPICQGTLREPVTI-DCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
sapiens]
Length = 395
Score = 42.0 bits (97), Expect = 7e-04
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 8/55 (14%)
Query: 9 ITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRY-------LETSKYCPIC 56
+T L + C +C G + TI +C H+FC+ C+ RY LE S CP+C
Sbjct: 7 VTSLADEVNCPICQGTLREPVTI-DCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
>gi|239755486 PREDICTED: tripartite motif-containing protein
64C-like isoform 2 [Homo sapiens]
Length = 447
Score = 41.6 bits (96), Expect = 0.001
Identities = 18/44 (40%), Positives = 26/44 (59%), Gaps = 4/44 (9%)
Query: 16 LMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSK---YCPIC 56
L+C +C YFID T +C+HSFC+ C+ E + CP+C
Sbjct: 13 LICCICVNYFIDPVTT-DCVHSFCRPCLCLCSEEGRAPMRCPLC 55
>gi|239755484 PREDICTED: tripartite motif-containing protein
64C-like isoform 1 [Homo sapiens]
Length = 450
Score = 41.6 bits (96), Expect = 0.001
Identities = 18/44 (40%), Positives = 26/44 (59%), Gaps = 4/44 (9%)
Query: 16 LMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSK---YCPIC 56
L+C +C YFID T +C+HSFC+ C+ E + CP+C
Sbjct: 13 LICCICVNYFIDPVTT-DCVHSFCRPCLCLCSEEGRAPMRCPLC 55
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,420,347
Number of Sequences: 37866
Number of extensions: 681674
Number of successful extensions: 4496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 126
Number of HSP's successfully gapped in prelim test: 238
Number of HSP's that attempted gapping in prelim test: 4131
Number of HSP's gapped (non-prelim): 540
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.