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Search of human proteins with 27734775
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
(248 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 489 e-138
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 379 e-105
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 359 1e-99
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 90 2e-18
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 86 2e-17
gi|4557509 cylicin 2 [Homo sapiens] 79 5e-15
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 78 6e-15
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 78 6e-15
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 77 1e-14
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 77 1e-14
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 75 5e-14
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 73 2e-13
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 73 2e-13
gi|151301228 formin binding protein 3 [Homo sapiens] 72 3e-13
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 72 4e-13
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 72 6e-13
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 70 2e-12
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 70 2e-12
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 69 3e-12
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 69 3e-12
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 69 3e-12
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 69 4e-12
gi|168229156 NFKB activating protein [Homo sapiens] 69 5e-12
gi|52426743 cisplatin resistance-associated overexpressed protei... 69 5e-12
gi|19923485 cisplatin resistance-associated overexpressed protei... 69 5e-12
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 68 6e-12
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 67 1e-11
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 67 1e-11
gi|27883882 P18SRP protein [Homo sapiens] 67 1e-11
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 67 1e-11
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 489 bits (1258), Expect = e-138
Identities = 248/248 (100%), Positives = 248/248 (100%)
Query: 1 MGKRDNRVAYMNPIAMARWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAE 60
MGKRDNRVAYMNPIAMARWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAE
Sbjct: 1 MGKRDNRVAYMNPIAMARWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAE 60
Query: 61 FEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDS 120
FEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDS
Sbjct: 61 FEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDS 120
Query: 121 EDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKR 180
EDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKR
Sbjct: 121 EDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKR 180
Query: 181 KKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKK 240
KKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKK
Sbjct: 181 KKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKK 240
Query: 241 SGSSHKSR 248
SGSSHKSR
Sbjct: 241 SGSSHKSR 248
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 379 bits (974), Expect = e-105
Identities = 201/245 (82%), Positives = 220/245 (89%), Gaps = 4/245 (1%)
Query: 1 MGKRDNRVAYMNPIAMARWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAE 60
MGKRDNRVAYMNPIAMAR RGP QS GPTIQDYLNRPRPTWEEVK+QLE KK GSKALAE
Sbjct: 1 MGKRDNRVAYMNPIAMARSRGPIQSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAE 60
Query: 61 FEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCR-SSSSSSSSDSSSSSSD 119
FEEKMNENWKKELEK REKLLSG+ESSSKKR+RKKK KKKS R SSSSSSSSDSSSSSSD
Sbjct: 61 FEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSD 120
Query: 120 SEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKK 179
SEDE+KKQGKRRKKKKNRS+KSS+SS E+ES+SK+S+KKKKKSKD TEKEKD++ LSKK
Sbjct: 121 SEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKK 180
Query: 180 RKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
R K Y +DKPLSSES SES+Y E+V+AKKK+ EERE+A EK KKKKK HKKHSKKKKK
Sbjct: 181 R-KMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKK--HKKHSKKKKK 237
Query: 240 KSGSS 244
K+ SS
Sbjct: 238 KAASS 242
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 359 bits (921), Expect = 1e-99
Identities = 191/235 (81%), Positives = 210/235 (89%), Gaps = 4/235 (1%)
Query: 11 MNPIAMARWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWK 70
MNPIAMAR RGP QS GPTIQDYLNRPRPTWEEVK+QLE KK GSKALAEFEEKMNENWK
Sbjct: 1 MNPIAMARSRGPIQSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWK 60
Query: 71 KELEKSREKLLSGNESSSKKRERKKKRKKKSCR-SSSSSSSSDSSSSSSDSEDEEKKQGK 129
KELEK REKLLSG+ESSSKKR+RKKK KKKS R SSSSSSSSDSSSSSSDSEDE+KKQGK
Sbjct: 61 KELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGK 120
Query: 130 RRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKP 189
RRKKKKNRS+KSS+SS E+ES+SK+S+KKKKKSKD TEKEKD++ LSKKR K Y +DKP
Sbjct: 121 RRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKR-KMYSEDKP 179
Query: 190 LSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSS 244
LSSES SES+Y E+V+AKKK+ EERE+A EK KKKKK HKKHSKKKKKK+ SS
Sbjct: 180 LSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKK--HKKHSKKKKKKAASS 232
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 89.7 bits (221), Expect = 2e-18
Identities = 52/222 (23%), Positives = 115/222 (51%), Gaps = 16/222 (7%)
Query: 33 YLNRP--RPTWE----EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNES 86
++++P +P W+ E ++++E +K G K E E K +++ ++ REK
Sbjct: 24 HISKPCTQPGWQSEIREREREIETRKEGKKE-RESERKKERREREKRKREREK------- 75
Query: 87 SSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146
+KRER KK KK + + +E++K+ K+ KK++ R+ K +
Sbjct: 76 -ERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERE 134
Query: 147 HESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQA 206
+ E + +E K++++ K+E EKE++ + K+ +K + + E + + +
Sbjct: 135 RKEERKREER-KERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR 193
Query: 207 KKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
K++++ ER++ +E+ K++KKK+ +K ++K +++ K R
Sbjct: 194 KERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER 235
Score = 60.1 bits (144), Expect = 2e-09
Identities = 37/167 (22%), Positives = 76/167 (45%), Gaps = 3/167 (1%)
Query: 18 RWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSR 77
R RG + G ++ R + E+ K+ E K+ K + + ++ K+ K
Sbjct: 79 RERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEE 138
Query: 78 EKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNR 137
K E KK ER+K+R++K + + + E +E+K+ +R +K++ +
Sbjct: 139 RKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198
Query: 138 SYKSSQSSTHESESESKESVKKKKKSKDET---EKEKDVRSLSKKRK 181
+ + + E + KE KK+++ +T EKE+ R +++K
Sbjct: 199 ERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 86.3 bits (212), Expect = 2e-17
Identities = 55/204 (26%), Positives = 107/204 (52%), Gaps = 16/204 (7%)
Query: 40 TWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKK 99
T E +++ E ++ + +E+ E KKE +K R+K G E K++ER+K+RK+
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKE-KKKRKKRERGKERERKRKEREKQRKE 88
Query: 100 KSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKK 159
+ + + + E+KQ RR++KK + K + ++ E K ++
Sbjct: 89 R--------REKERRKRKKEKKKRERKQRGRRERKKKKERKERERE-NKQRRERKRKKRR 139
Query: 160 KKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAK 219
KKK + E ++EK+ +KRKK +++ E E + +E + K++ R E RE+ K
Sbjct: 140 KKKRRKERKREKERGKRERKRKKRKKEER----EKKRERNRKE--RKKERERKERRERKK 193
Query: 220 EKVKKKKKKQHKKHSKKKKKKSGS 243
E+ K+++KK+ +K +K +++ S
Sbjct: 194 ERKKERRKKKERKKDRKTDRQTDS 217
Score = 79.7 bits (195), Expect = 2e-15
Identities = 39/179 (21%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Query: 70 KKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGK 129
++E E+ +E+ E +KRER+K+RK++ + + + +E+++ +
Sbjct: 31 QRESERKKER----REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
Query: 130 RRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKP 189
+ +++K R + + E + + KKKK+ K+ + K R +K+++ K
Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRK----KK 142
Query: 190 LSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
E E + + + +KKR+ EERE+ +E+ +K++KK+ ++ ++++KK + +
Sbjct: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Score = 79.7 bits (195), Expect = 2e-15
Identities = 42/181 (23%), Positives = 96/181 (53%), Gaps = 2/181 (1%)
Query: 67 ENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKK 126
E+ +K+ + REK E +KRER KK KKK + + + + +E++
Sbjct: 33 ESERKKERREREKRKREREKE-RKRERGKKEKKKR-KKRERGKERERKRKEREKQRKERR 90
Query: 127 QGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPD 186
+ +RRK+KK + + + + KE ++++++K E+++ R K+RK+ +
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Query: 187 DKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHK 246
+ E + +E+ + K++R +ER++ +E+ +++++K+ +K ++KKK+ K
Sbjct: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK 210
Query: 247 S 247
+
Sbjct: 211 T 211
Score = 58.2 bits (139), Expect = 7e-09
Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 7/143 (4%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101
E K++ E KK K E K KK+ K RE+ +K+ RKKKR+K+
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERK-----KKKERKERERENKQRRERKRKKRRKKKRRKER 147
Query: 102 CRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKK 161
R E E+K++ R+++KK R K + E + E ++ KK++
Sbjct: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK--KKER 205
Query: 162 KSKDETEKEKDVRSLSKKRKKSY 184
K +T+++ D + R+ ++
Sbjct: 206 KKDRKTDRQTDSQVFRPLRESAF 228
Score = 55.5 bits (132), Expect = 4e-08
Identities = 42/164 (25%), Positives = 73/164 (44%), Gaps = 15/164 (9%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERK- 94
+ R E K++ +K K E EK KKE +K RE+ G KK+ERK
Sbjct: 64 KKRKKRERGKERERKRKEREKQRKERREKERRKRKKE-KKKRERKQRGRRERKKKKERKE 122
Query: 95 -----KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHES 149
K+R+++ + + E+K+ KR+K+++ + + ++ +
Sbjct: 123 RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE-RKK 181
Query: 150 ESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSE 193
E E KE ++KK+ K E K+K+ RKK D+ S+
Sbjct: 182 ERERKERRERKKERKKERRKKKE-------RKKDRKTDRQTDSQ 218
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 78.6 bits (192), Expect = 5e-15
Identities = 54/211 (25%), Positives = 101/211 (47%), Gaps = 15/211 (7%)
Query: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC 102
E+K+ ++ K G EEK++ KK+ +K ++ G +S+++ + K KK +
Sbjct: 133 ELKQGKKDSKKGKDIEKGKEEKLDA--KKDSKKGKKDAEKGKDSATESEDEKGGAKKDNK 190
Query: 103 RSSSSSSSSDSSSSSSDSE----DEEKKQGKRRKKKKNRSYKSSQS--STHESESESKES 156
+ S+ S++ S+ E +++ K+GK+ KK S Q+ + + + + K+
Sbjct: 191 KDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKD 250
Query: 157 VKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKK-------K 209
K +SKD + K+++ K +KK D + ES + AKK K
Sbjct: 251 ANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEK 310
Query: 210 RRCEEREQAKEKVKKKKKKQHKKHSKKKKKK 240
+ ++ AK+ KK KK KK++KK +KK
Sbjct: 311 ESADSKKDAKKNAKKDAKKDAKKNAKKDEKK 341
Score = 62.8 bits (151), Expect = 3e-10
Identities = 54/210 (25%), Positives = 94/210 (44%), Gaps = 18/210 (8%)
Query: 46 KQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSS 105
K + SKA ++ ++ +K+ S +L G + S K ++ +K +++K
Sbjct: 100 KPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKK 159
Query: 106 SSSSSSDSSSSSSDS--EDEEKKQGKRRKKKKNRSYK----SSQSSTHESESESKESVKK 159
S + DS E E++K G KK N+ K + S ESE E + K
Sbjct: 160 DSKKGKKDAEKGKDSATESEDEKGGA---KKDNKKDKKDSNKGKDSATESEGEKGGTEKD 216
Query: 160 KKKSKDETEKEKDVR---SLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEERE 216
KK K +++K KD K +K D K +++ D ++D + KK + ++++
Sbjct: 217 SKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKK 276
Query: 217 ------QAKEKVKKKKKKQHKKHSKKKKKK 240
+K+ VKK+ KK K +KK KK
Sbjct: 277 PSSTDSDSKDDVKKESKKDATKDAKKVAKK 306
Score = 60.8 bits (146), Expect = 1e-09
Identities = 56/215 (26%), Positives = 90/215 (41%), Gaps = 42/215 (19%)
Query: 42 EEVKKQLENKKTGSKALAEFEE------KMNENWKKELEKSREKLLSGNESSSKKRERKK 95
++ KK ++ + G + E E+ K N+ KK+ K ++ + K
Sbjct: 159 KDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSK 218
Query: 96 KRKKKSCRSSSSS---------SSSDSSSSSSDSEDEEKKQGKRRKK--KKNRSYKSSQS 144
K KK S + S+ D ++ +E K K+ K KK + K S
Sbjct: 219 KGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPS 278
Query: 145 STHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDV 204
ST +S+SK+ VKK+ K KD T KD + ++KK + +E
Sbjct: 279 ST---DSDSKDDVKKESK-KDAT---KDAKKVAKKDTE------------------KESA 313
Query: 205 QAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
+KK + ++ AK+ KK KK KK +KKK K
Sbjct: 314 DSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
Score = 59.3 bits (142), Expect = 3e-09
Identities = 49/175 (28%), Positives = 76/175 (43%), Gaps = 15/175 (8%)
Query: 85 ESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSED--------EEKKQGKRRKKKKN 136
E SK E KK + K+ + ++ S S+ DS+ EEK K+ KK
Sbjct: 106 EVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK 165
Query: 137 RSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKK-SYPDDKPLSSESS 195
+ + + S ESE E + K KK K ++ K KD + S+ K + D K +S
Sbjct: 166 KDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSK 225
Query: 196 SESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSK------KKKKKSGSS 244
D ++QA K ++ + K+ K + K KK +K K KKK S+
Sbjct: 226 KGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSST 280
Score = 38.5 bits (88), Expect = 0.005
Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 26/108 (24%)
Query: 140 KSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESD 199
K++Q T +SESE K+ K KK KD EK K+ + +KK K D +S++ES+
Sbjct: 121 KTTQKDTTDSESELKQGKKDSKKGKD-IEKGKEEKLDAKKDSKKGKKDAEKGKDSATESE 179
Query: 200 YEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247
E K KK +KK KK S S
Sbjct: 180 DE-------------------------KGGAKKDNKKDKKDSNKGKDS 202
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 78.2 bits (191), Expect = 6e-15
Identities = 56/198 (28%), Positives = 100/198 (50%), Gaps = 16/198 (8%)
Query: 60 EFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKR------KKKSCRSSSSSSSSDS 113
EF + + K++L + ++L E KK++RKKK+ K K +SSSSSSSS S
Sbjct: 211 EFLKSLTTKQKQKLLRKLDRL----EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSS 266
Query: 114 SSSS---SDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKE 170
SSSS S+S E + K +K ++ + K+ S + S+SE K+ KK+K +E
Sbjct: 267 SSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDK-SKKRKLHEELSSS 325
Query: 171 KDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQH 230
R +K++ + + S E S S + D +++ + E+ ++ K +
Sbjct: 326 HHNREKAKEKPRFLKHES--SREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGR 383
Query: 231 KKHSKKKKKKSGSSHKSR 248
++ S++ + +S S+K R
Sbjct: 384 EERSRRSRSRSPGSYKQR 401
Score = 57.0 bits (136), Expect = 1e-08
Identities = 46/216 (21%), Positives = 85/216 (39%), Gaps = 3/216 (1%)
Query: 32 DYLNRPRPTWEEVKKQLENKKTGSKA-LAEFEEKMNENWKKELEKSREKLLSGNESSSKK 90
D L + + + KK+ + ++ K + + + E S S + + KK
Sbjct: 229 DRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKK 288
Query: 91 RERKKKRKKK-SCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHES 149
+RKK++K K S ++S S D S E+ R K K+ + +SS +S
Sbjct: 289 IQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDS 348
Query: 150 ESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKK 209
+ +S KK + K EK R R +++ S S S Y++ K+
Sbjct: 349 KWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHG-REERSRRSRSRSPGSYKQRETRKRA 407
Query: 210 RRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSH 245
+R EQ++ + + K ++ G +H
Sbjct: 408 QRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTH 443
Score = 53.1 bits (126), Expect = 2e-07
Identities = 41/147 (27%), Positives = 65/147 (44%), Gaps = 7/147 (4%)
Query: 109 SSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETE 168
+++D S SE EE + + K + + E + K+ +KKKK +
Sbjct: 191 TANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRS 250
Query: 169 KEKDVRSLSKKRKKSYPDDKPLSSESSSESD---YEEDVQAK--KKRRC--EEREQAKEK 221
K K +S S S +SESSSES+ E+ +Q K KK +C ++EK
Sbjct: 251 KHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEK 310
Query: 222 VKKKKKKQHKKHSKKKKKKSGSSHKSR 248
K KK+K H++ S + + K R
Sbjct: 311 DKSKKRKLHEELSSSHHNREKAKEKPR 337
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 78.2 bits (191), Expect = 6e-15
Identities = 41/140 (29%), Positives = 78/140 (55%), Gaps = 17/140 (12%)
Query: 93 RKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESE 152
+KKK+KKK ++ + + ++E+EE+K+GKR++K+K + E E +
Sbjct: 1 KKKKKKKKE---------TEETEETEETEEEEEKEGKRKEKRKEKR--------KEKEKK 43
Query: 153 SKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRC 212
K +K+K K+E EK++ + KK ++ +++ E E + EE + KKK++
Sbjct: 44 KKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR 103
Query: 213 EEREQAKEKVKKKKKKQHKK 232
+E+ +EK KK+++K KK
Sbjct: 104 RRKEEEEEKKKKRRRKTKKK 123
Score = 65.1 bits (157), Expect = 5e-11
Identities = 37/122 (30%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Query: 64 KMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDE 123
K + KKE E++ E+ E K+ +RK+KRK+K + + + + E+E
Sbjct: 1 KKKKKKKKETEET-EETEETEEEEEKEGKRKEKRKEKR-KEKEKKKKTKETEKRKEKEEE 58
Query: 124 EKKQGKRRKKKKNRSYKSSQSSTHESESES--KESVKKKKKSKDETEKEKDVRSLSKKRK 181
EKK+ ++RKKKK + + E E E KE +++KK K KE++ K+R+
Sbjct: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Query: 182 KS 183
K+
Sbjct: 119 KT 120
Score = 64.3 bits (155), Expect = 9e-11
Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 13/123 (10%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101
EE ++ E ++ K + +EK E KK+ K EK E KKR+RK+K+KK+
Sbjct: 14 EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKE-KEEEEKKRKRKRKKKKEE 72
Query: 102 CRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKK 161
+ + E+EEK++G+RRKKKK R K E E E K+ ++K
Sbjct: 73 -----EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK-------EEEEEKKKKRRRKT 120
Query: 162 KSK 164
K K
Sbjct: 121 KKK 123
Score = 41.2 bits (95), Expect = 8e-04
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 22/100 (22%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95
+ + T + +K+ E KK K + EE+ E ++E E+ +E+ + ++R++KK
Sbjct: 45 KTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEE---EEKEEGRRRKKKK 101
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKK 135
KR++K E+EEKK+ +RRK KK
Sbjct: 102 KRRRK-------------------EEEEEKKKKRRRKTKK 122
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 77.0 bits (188), Expect = 1e-14
Identities = 55/252 (21%), Positives = 104/252 (41%), Gaps = 21/252 (8%)
Query: 2 GKRDNRVAYMNPIAMARWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLE------NKKTGS 55
G R ++ + N + Q+ +++ + R R + +E N++ G
Sbjct: 247 GDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGG 306
Query: 56 KALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSS 115
++ + K + K + R + + S ++ R R+K R++ S S +
Sbjct: 307 RSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRK 366
Query: 116 SSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRS 175
S S S +K++ R K K+ K + +E K++ K+KD
Sbjct: 367 SRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR--------- 417
Query: 176 LSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSK 235
K+R+K DK E E ++E+D +K E+EQ KEK ++K + + +
Sbjct: 418 -DKEREKDREKDKEKDREREREKEHEKDRDKEK-----EKEQDKEKEREKDRSKEIDEKR 471
Query: 236 KKKKKSGSSHKS 247
KK KKS + +S
Sbjct: 472 KKDKKSRTPPRS 483
Score = 73.6 bits (179), Expect = 2e-13
Identities = 62/227 (27%), Positives = 109/227 (48%), Gaps = 24/227 (10%)
Query: 42 EEVKKQLENKKTGSKALAEFEE-KMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKK 100
EEV K++ ++ A E E K NE ++ +SR S + SSSK R+K+ + K
Sbjct: 276 EEVMKRVREAQSFISAAIEPESGKSNE---RKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 332
Query: 101 SCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKK 160
RS S + S S+ KK+ K R+++K+RS S+ ++ + KE + K
Sbjct: 333 H-RSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 391
Query: 161 KKSKD-------ETEKEKDV---RSLSKKRKKSYPDDKPLSSESSSESDYEEDV-QAKKK 209
+K ++ E EKEK+ + K+R+K DK E E ++E+D + K+K
Sbjct: 392 EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 451
Query: 210 RRCEEREQAKEKVKK--------KKKKQHKKHSKKKKKKSGSSHKSR 248
+ +E+E+ K++ K+ KK + + ++ SS + R
Sbjct: 452 EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 498
Score = 67.8 bits (164), Expect = 8e-12
Identities = 49/212 (23%), Positives = 90/212 (42%), Gaps = 4/212 (1%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95
R + ++ K E +K+ S++ + + K KE E+ +EK K+RE++K
Sbjct: 350 RSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK 409
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKE 155
+R K R + + EK+ K R K+K K + SKE
Sbjct: 410 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKE---KEQDKEKEREKDRSKE 466
Query: 156 SVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEER 215
+K+KK K + + S++ + S + + S SSS S +K R
Sbjct: 467 IDEKRKKDKKSRTPPRSYNA-SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP 525
Query: 216 EQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247
+K KK++K++ ++++++S S KS
Sbjct: 526 RSRNKKDKKREKERDHISERRERERSTSMRKS 557
Score = 66.6 bits (161), Expect = 2e-11
Identities = 51/225 (22%), Positives = 96/225 (42%), Gaps = 21/225 (9%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERK 94
+R R + +K K + + E + + +KE EK +E+ + + ++++R+
Sbjct: 367 SRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDRE 426
Query: 95 KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGK---------RRKKKKNRSYKSSQSS 145
K ++K R D +D+EK++ K R+K KK+R+ S ++
Sbjct: 427 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 486
Query: 146 THESESESKESVKKKKKSK------DETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESD 199
+ S S S+E +++ +S +T K K RS S + + DK E S+
Sbjct: 487 SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK--KDKKREKERDHISE 544
Query: 200 YEEDVQAKKKRRCEEREQAKEKVKKK----KKKQHKKHSKKKKKK 240
E ++ R+ KEK++K K+K+H K K
Sbjct: 545 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 589
Score = 63.5 bits (153), Expect = 2e-10
Identities = 47/209 (22%), Positives = 94/209 (44%), Gaps = 17/209 (8%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERK 94
NR R ++ ++ K SK+ + + + + + + +REK+ K RE++
Sbjct: 339 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE 398
Query: 95 KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESK 154
++R+K+ + + D D+E+++ + + K+K+R + E E E
Sbjct: 399 REREKEREKEKERGKNKD--------RDKEREKDREKDKEKDRERE------REKEHEKD 444
Query: 155 ESVKKKKKSKDETEKEKD-VRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKR-RC 212
+K+K+ E E+EKD + + +KRKK P S ++S + +++R R
Sbjct: 445 RDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 504
Query: 213 EEREQAKEK-VKKKKKKQHKKHSKKKKKK 240
R K +K+K + S+ KK K
Sbjct: 505 SSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533
Score = 58.9 bits (141), Expect = 4e-09
Identities = 39/204 (19%), Positives = 96/204 (47%), Gaps = 6/204 (2%)
Query: 50 NKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKK--KSCRSSSS 107
+K+ ++ + +E++ E +E E+ REK + K ++R K+R+K + +
Sbjct: 375 DKRKDTREKIKEKERVKEK-DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR 433
Query: 108 SSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESES---KESVKKKKKSK 164
+ +++EK+Q K ++++K+RS + + + +S + + ++ +S
Sbjct: 434 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 493
Query: 165 DETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKK 224
+ + RS S+ + S + S S S ++D + +K+R + +E+
Sbjct: 494 SRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTS 553
Query: 225 KKKKQHKKHSKKKKKKSGSSHKSR 248
+K + + K+K +K+ +S K +
Sbjct: 554 MRKSSNDRDGKEKLEKNSTSLKEK 577
Score = 58.9 bits (141), Expect = 4e-09
Identities = 41/193 (21%), Positives = 91/193 (47%), Gaps = 6/193 (3%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERK 94
N+ R E ++ + +K + E E++ ++ KE EK ++K + SK+ + K
Sbjct: 414 NKDRDKEREKDREKDKEKDRER---EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470
Query: 95 KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESK 154
+K+ KKS S ++S S SSS + + R + +++ K S + S +K
Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530
Query: 155 ESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDK---PLSSESSSESDYEEDVQAKKKRR 211
+ K++K+ +E+ + RS S ++ + D K +S S E ++ ++ + +
Sbjct: 531 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590
Query: 212 CEEREQAKEKVKK 224
++++ + + K
Sbjct: 591 VDDKDAPRTEENK 603
Score = 57.4 bits (137), Expect = 1e-08
Identities = 53/187 (28%), Positives = 81/187 (43%), Gaps = 19/187 (10%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGN---ESSSKKR 91
+R + +E K+ E +K SK E +EK +K+ +KSR S N S S R
Sbjct: 444 DRDKEKEKEQDKEKEREKDRSK---EIDEK-----RKKDKKSRTPPRSYNASRRSRSSSR 495
Query: 92 ERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESES 151
ER+++R + S RS +S + SS S S R KK K R K + E
Sbjct: 496 ERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS------RNKKDKKRE-KERDHISERRER 548
Query: 152 ESKESVKKKKKSKDETEK-EKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKR 210
E S++K +D EK EK+ SL +K PD ++ E+ + +
Sbjct: 549 ERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNG 608
Query: 211 RCEEREQ 217
C+ E+
Sbjct: 609 NCQLNEE 615
Score = 57.0 bits (136), Expect = 1e-08
Identities = 47/205 (22%), Positives = 91/205 (44%), Gaps = 7/205 (3%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWK-KELEKSREKLLSGNESSSKKRERK 94
+ R +E K + K K + +EK E + KE EK R+K + K+RE+
Sbjct: 403 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 462
Query: 95 KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESK 154
+ ++ R S + S ++ + +RR++ ++ S S T + +S
Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522
Query: 155 ESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEE 214
S + + K + EKE+D S ++R++S K SS++ D +E ++ K +E
Sbjct: 523 PSPRSRNKKDKKREKERDHISERRERERSTSMRK-----SSNDRDGKEKLE-KNSTSLKE 576
Query: 215 REQAKEKVKKKKKKQHKKHSKKKKK 239
+E KE K+ K + + ++
Sbjct: 577 KEHNKEPDSSVSKEVDDKDAPRTEE 601
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 77.0 bits (188), Expect = 1e-14
Identities = 55/252 (21%), Positives = 104/252 (41%), Gaps = 21/252 (8%)
Query: 2 GKRDNRVAYMNPIAMARWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLE------NKKTGS 55
G R ++ + N + Q+ +++ + R R + +E N++ G
Sbjct: 131 GDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGG 190
Query: 56 KALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSS 115
++ + K + K + R + + S ++ R R+K R++ S S +
Sbjct: 191 RSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRK 250
Query: 116 SSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRS 175
S S S +K++ R K K+ K + +E K++ K+KD
Sbjct: 251 SRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR--------- 301
Query: 176 LSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSK 235
K+R+K DK E E ++E+D +K E+EQ KEK ++K + + +
Sbjct: 302 -DKEREKDREKDKEKDREREREKEHEKDRDKEK-----EKEQDKEKEREKDRSKEIDEKR 355
Query: 236 KKKKKSGSSHKS 247
KK KKS + +S
Sbjct: 356 KKDKKSRTPPRS 367
Score = 73.6 bits (179), Expect = 2e-13
Identities = 62/227 (27%), Positives = 109/227 (48%), Gaps = 24/227 (10%)
Query: 42 EEVKKQLENKKTGSKALAEFEE-KMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKK 100
EEV K++ ++ A E E K NE ++ +SR S + SSSK R+K+ + K
Sbjct: 160 EEVMKRVREAQSFISAAIEPESGKSNE---RKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 216
Query: 101 SCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKK 160
RS S + S S+ KK+ K R+++K+RS S+ ++ + KE + K
Sbjct: 217 H-RSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 275
Query: 161 KKSKD-------ETEKEKDV---RSLSKKRKKSYPDDKPLSSESSSESDYEEDV-QAKKK 209
+K ++ E EKEK+ + K+R+K DK E E ++E+D + K+K
Sbjct: 276 EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 335
Query: 210 RRCEEREQAKEKVKK--------KKKKQHKKHSKKKKKKSGSSHKSR 248
+ +E+E+ K++ K+ KK + + ++ SS + R
Sbjct: 336 EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 382
Score = 67.8 bits (164), Expect = 8e-12
Identities = 49/212 (23%), Positives = 90/212 (42%), Gaps = 4/212 (1%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95
R + ++ K E +K+ S++ + + K KE E+ +EK K+RE++K
Sbjct: 234 RSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK 293
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKE 155
+R K R + + EK+ K R K+K K + SKE
Sbjct: 294 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKE---KEQDKEKEREKDRSKE 350
Query: 156 SVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEER 215
+K+KK K + + S++ + S + + S SSS S +K R
Sbjct: 351 IDEKRKKDKKSRTPPRSYNA-SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP 409
Query: 216 EQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247
+K KK++K++ ++++++S S KS
Sbjct: 410 RSRNKKDKKREKERDHISERRERERSTSMRKS 441
Score = 66.6 bits (161), Expect = 2e-11
Identities = 51/225 (22%), Positives = 96/225 (42%), Gaps = 21/225 (9%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERK 94
+R R + +K K + + E + + +KE EK +E+ + + ++++R+
Sbjct: 251 SRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDRE 310
Query: 95 KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGK---------RRKKKKNRSYKSSQSS 145
K ++K R D +D+EK++ K R+K KK+R+ S ++
Sbjct: 311 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 370
Query: 146 THESESESKESVKKKKKSK------DETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESD 199
+ S S S+E +++ +S +T K K RS S + + DK E S+
Sbjct: 371 SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK--KDKKREKERDHISE 428
Query: 200 YEEDVQAKKKRRCEEREQAKEKVKKK----KKKQHKKHSKKKKKK 240
E ++ R+ KEK++K K+K+H K K
Sbjct: 429 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 473
Score = 63.5 bits (153), Expect = 2e-10
Identities = 47/209 (22%), Positives = 94/209 (44%), Gaps = 17/209 (8%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERK 94
NR R ++ ++ K SK+ + + + + + + +REK+ K RE++
Sbjct: 223 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE 282
Query: 95 KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESK 154
++R+K+ + + D D+E+++ + + K+K+R + E E E
Sbjct: 283 REREKEREKEKERGKNKD--------RDKEREKDREKDKEKDRERE------REKEHEKD 328
Query: 155 ESVKKKKKSKDETEKEKD-VRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKR-RC 212
+K+K+ E E+EKD + + +KRKK P S ++S + +++R R
Sbjct: 329 RDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 388
Query: 213 EEREQAKEK-VKKKKKKQHKKHSKKKKKK 240
R K +K+K + S+ KK K
Sbjct: 389 SSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417
Score = 58.9 bits (141), Expect = 4e-09
Identities = 39/204 (19%), Positives = 96/204 (47%), Gaps = 6/204 (2%)
Query: 50 NKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKK--KSCRSSSS 107
+K+ ++ + +E++ E +E E+ REK + K ++R K+R+K + +
Sbjct: 259 DKRKDTREKIKEKERVKEK-DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR 317
Query: 108 SSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESES---KESVKKKKKSK 164
+ +++EK+Q K ++++K+RS + + + +S + + ++ +S
Sbjct: 318 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 377
Query: 165 DETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKK 224
+ + RS S+ + S + S S S ++D + +K+R + +E+
Sbjct: 378 SRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTS 437
Query: 225 KKKKQHKKHSKKKKKKSGSSHKSR 248
+K + + K+K +K+ +S K +
Sbjct: 438 MRKSSNDRDGKEKLEKNSTSLKEK 461
Score = 58.9 bits (141), Expect = 4e-09
Identities = 41/193 (21%), Positives = 91/193 (47%), Gaps = 6/193 (3%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERK 94
N+ R E ++ + +K + E E++ ++ KE EK ++K + SK+ + K
Sbjct: 298 NKDRDKEREKDREKDKEKDRER---EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354
Query: 95 KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESK 154
+K+ KKS S ++S S SSS + + R + +++ K S + S +K
Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414
Query: 155 ESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDK---PLSSESSSESDYEEDVQAKKKRR 211
+ K++K+ +E+ + RS S ++ + D K +S S E ++ ++ + +
Sbjct: 415 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474
Query: 212 CEEREQAKEKVKK 224
++++ + + K
Sbjct: 475 VDDKDAPRTEENK 487
Score = 57.4 bits (137), Expect = 1e-08
Identities = 53/187 (28%), Positives = 81/187 (43%), Gaps = 19/187 (10%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGN---ESSSKKR 91
+R + +E K+ E +K SK E +EK +K+ +KSR S N S S R
Sbjct: 328 DRDKEKEKEQDKEKEREKDRSK---EIDEK-----RKKDKKSRTPPRSYNASRRSRSSSR 379
Query: 92 ERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESES 151
ER+++R + S RS +S + SS S S R KK K R K + E
Sbjct: 380 ERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS------RNKKDKKRE-KERDHISERRER 432
Query: 152 ESKESVKKKKKSKDETEK-EKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKR 210
E S++K +D EK EK+ SL +K PD ++ E+ + +
Sbjct: 433 ERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNG 492
Query: 211 RCEEREQ 217
C+ E+
Sbjct: 493 NCQLNEE 499
Score = 57.0 bits (136), Expect = 1e-08
Identities = 47/205 (22%), Positives = 91/205 (44%), Gaps = 7/205 (3%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWK-KELEKSREKLLSGNESSSKKRERK 94
+ R +E K + K K + +EK E + KE EK R+K + K+RE+
Sbjct: 287 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 346
Query: 95 KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESK 154
+ ++ R S + S ++ + +RR++ ++ S S T + +S
Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406
Query: 155 ESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEE 214
S + + K + EKE+D S ++R++S K SS++ D +E ++ K +E
Sbjct: 407 PSPRSRNKKDKKREKERDHISERRERERSTSMRK-----SSNDRDGKEKLE-KNSTSLKE 460
Query: 215 REQAKEKVKKKKKKQHKKHSKKKKK 239
+E KE K+ K + + ++
Sbjct: 461 KEHNKEPDSSVSKEVDDKDAPRTEE 485
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 75.1 bits (183), Expect = 5e-14
Identities = 60/221 (27%), Positives = 105/221 (47%), Gaps = 31/221 (14%)
Query: 52 KTGSKALAEFEEKM--NENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC------- 102
K+ SK+ + EEK+ N+N K +S + S ++S S+ +ER+ + +K+
Sbjct: 264 KSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQ 323
Query: 103 -------RSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHES------ 149
RS S S S S S S+ ++K++G++R ++++RS S+S + S
Sbjct: 324 EKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSK 383
Query: 150 -ESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKK 208
+S++ S KKKK+ D ++ RS+SK+R+ + SESS E A
Sbjct: 384 RDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHA-------KSESSQREGRGESENAGT 436
Query: 209 KRRCEEREQAKEKVKKKKKKQHKKHSKK-KKKKSGSSHKSR 248
+ R ++ K K + + SK K +S S +SR
Sbjct: 437 NQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSR 477
Score = 71.2 bits (173), Expect = 8e-13
Identities = 57/229 (24%), Positives = 95/229 (41%), Gaps = 34/229 (14%)
Query: 46 KQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSS 105
++L+ + + + E+K ++ +SR S S+ R R + +K RS
Sbjct: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSR--------SHSRSRSRSRHSRKSRSRSG 209
Query: 106 SSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRS--YKSSQSSTHESESESKESVKKKKKS 163
SS SS S S S S + + + R + ++RS KS S +S S S + K + KS
Sbjct: 210 SSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKS 269
Query: 164 KDETEKE---KDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKR---------- 210
KD+ E++ D K R S K S S E EE+ + R
Sbjct: 270 KDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ 329
Query: 211 -----------RCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
R R ++K K K+K +K+ ++ S+ + + S +SR
Sbjct: 330 SRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSR 378
Score = 67.8 bits (164), Expect = 8e-12
Identities = 54/221 (24%), Positives = 105/221 (47%), Gaps = 17/221 (7%)
Query: 21 GPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEK-MNENWKKELEK--SR 77
G +S P+ ++ R +E +++E +K GS + +EK + ++ + K SR
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRSQE--RRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSR 341
Query: 78 EKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNR 137
+ S ++S K++ RK+ R++ RS S S S S S + + K++K+ +R
Sbjct: 342 SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR 401
Query: 138 SYKSSQSSTHESESESKESVKKKKKSKDETEK---EKDVRSLSKKRKKSYPDDKPLSSES 194
S S S + E E +S +++ + E+E ++ RS S+ KS P+ L SES
Sbjct: 402 SQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPN---LPSES 458
Query: 195 SSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSK 235
S S ++ K R + +++ + + + + HS+
Sbjct: 459 RSRS------KSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 67.0 bits (162), Expect = 1e-11
Identities = 57/222 (25%), Positives = 106/222 (47%), Gaps = 26/222 (11%)
Query: 52 KTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKR--------KKKSCR 103
K+ S++ + K ++ EKSR + S +S SK +++ +++ K KS
Sbjct: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290
Query: 104 SSSSSSSSDSSSSSSDSEDEEKKQGK-----------RRKKKKNRSYKSSQSSTHESESE 152
S S S S S S + EE+K+G R+ + ++RS K S S S+
Sbjct: 291 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS-KGGSRSRSRSRSK 349
Query: 153 SKESVKKKKKSKDETEKEKDVRSLSKKRKK--SYPDDKPLSSESSSESDYEEDVQAKKKR 210
SK+ K +K+S++E+ RS S++ +K S D K SS+ + D + R
Sbjct: 350 SKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSR 409
Query: 211 RC-EEREQAKEKVKKKKKKQHKKH---SKKKKKKSGSSHKSR 248
+ERE AK + +++ + ++ +++ + +S S+ KS+
Sbjct: 410 SVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSK 451
Score = 63.2 bits (152), Expect = 2e-10
Identities = 52/206 (25%), Positives = 95/206 (46%), Gaps = 15/206 (7%)
Query: 46 KQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSS 105
++ ++ SK+ + + + KSR + S + S SKK + + K+KS S
Sbjct: 202 RKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSR--SQSRSRSKKEKSRSPSKEKS--RS 257
Query: 106 SSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRS---YKSSQSSTHESESESKESVKKKKK 162
S S+ S S S D +E+ + K K+RS +KS S S+ E K+
Sbjct: 258 RSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSV 317
Query: 163 SKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKV 222
S+ ++++ +S S+ R K S S S S + + K ++R E +++ +
Sbjct: 318 SRGRSQEKSLRQSRSRSRSKG-------GSRSRSRSRSKSKDKRKGRKRSREESRSRSRS 370
Query: 223 KKKKKKQHKKHSKKKKKKSGSSHKSR 248
+ K ++ K+ S K+ K+GSS K +
Sbjct: 371 RSKSERSRKRGS-KRDSKAGSSKKKK 395
Score = 60.5 bits (145), Expect = 1e-09
Identities = 52/204 (25%), Positives = 81/204 (39%), Gaps = 27/204 (13%)
Query: 70 KKELEKSREKLLSGNESSSKKRERKKKR---KKKSCRSSSSSSSSDSSSSSSDSEDEEKK 126
K KSR + SG+ S SK R R + R KK+ RS S S S S+ S + K
Sbjct: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKD 271
Query: 127 QGKRR---------------KKKKNRSYKSSQSSTHESESESKESV-------KKKKKSK 164
Q + + + K++S S+S E E + SV K ++S+
Sbjct: 272 QAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSR 331
Query: 165 DETEKEKDVRSLSKKRKKSYPDDK--PLSSESSSESDYEEDVQAKKKRRCEEREQAKEKV 222
+ + RS S+ R KS K S E S + ++R +R+
Sbjct: 332 SRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS 391
Query: 223 KKKKKKQHKKHSKKKKKKSGSSHK 246
KKKKK+ + + +S S +
Sbjct: 392 KKKKKEDTDRSQSRSPSRSVSKER 415
Score = 56.6 bits (135), Expect = 2e-08
Identities = 49/232 (21%), Positives = 90/232 (38%), Gaps = 21/232 (9%)
Query: 38 RPTWEEVKKQLE--------NKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSK 89
R +W+++K + + G K E + K+ LEK ++G +
Sbjct: 114 RCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLV 173
Query: 90 KRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHES 149
+ + +R++ RS S S S S S S K ++RS S+S +
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233
Query: 150 ESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDD-------------KPLSSESSS 196
S KK+KS+ ++++ RS S + +S D KP S S
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 197 ESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
+ ++RR EE ++ + ++K ++ + + K GS +SR
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR 345
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 73.2 bits (178), Expect = 2e-13
Identities = 69/230 (30%), Positives = 102/230 (44%), Gaps = 31/230 (13%)
Query: 38 RPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKS---REKLLSGNESSSKKRERK 94
+ T + KK + + SK + +K+ +N KK+ +K ++ + ES K ERK
Sbjct: 286 KDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERK 345
Query: 95 -------------KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKS 141
KK+ K S+ + S D+ + +DS + KK K KKK+ K
Sbjct: 346 DTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNL-KKASKNDDKKKDAK-KI 403
Query: 142 SQSSTHESESESKESVKKKKKSKDET-----------EKEKDVRSLSKKRKKSYPDDKPL 190
+ S+ ESE ESKES K +KK K ++ E+ D S K K D+
Sbjct: 404 TFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKK 463
Query: 191 SSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKK 240
+ S + D ++D AKK E E E K KK + KK SKK KK
Sbjct: 464 GKKDSKKDDKKKD--AKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKK 511
Score = 72.0 bits (175), Expect = 4e-13
Identities = 57/202 (28%), Positives = 106/202 (52%), Gaps = 16/202 (7%)
Query: 49 ENKKTGSKALAEFEEKMNENWKKELE-KSREKLLSGNESSSKKRERKKKRKKKSCRSSSS 107
+ KK K + ++K + + + + +S + + N+S + K+ K KKK + +
Sbjct: 346 DTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITF 405
Query: 108 SSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDET 167
S+ S+S S +S+ +EKK K K +S K+ + ST +++SE K KK K KDE
Sbjct: 406 STDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEEST-DADSEPKGDSKKGK--KDEK 462
Query: 168 EKEKDVRSLSKKRKKSYPDDKPLSSESSSES-DYEEDVQAKK-KRRCEEREQAKEKVKKK 225
+ +KD SKK DDK ++ ++ES + E D++ KK K+ +E++ +K+ +KK
Sbjct: 463 KGKKD----SKK------DDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKD 512
Query: 226 KKKQHKKHSKKKKKKSGSSHKS 247
+K + + + S + K+
Sbjct: 513 ARKDTESTDAEFDESSKTGFKT 534
Score = 69.7 bits (169), Expect = 2e-12
Identities = 69/255 (27%), Positives = 117/255 (45%), Gaps = 51/255 (20%)
Query: 45 KKQLENKKTGSKALAEF--EEKMNENWKKELEKSREK-------LLSGNESSSKKRERK- 94
KK L+ KT + ++E E +N ++ + +S ++ L + ++++SK K
Sbjct: 221 KKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKY 280
Query: 95 ----KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKK-NRSYKSSQSSTHES 149
KK KK+ + SS + S DS + DS+ +K K KKK + +S+ + + +S
Sbjct: 281 TKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDS 340
Query: 150 ESESKESVKKKKKSKDETEKE----------------KDVRSLSKKRKK-SYPDDKP--- 189
+ E K++ K KKK K + +K+ KD R+ S+ KK S DDK
Sbjct: 341 KDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDA 400
Query: 190 ----LSSESSSESDYEEDVQAKKKRRCEEREQAKEKVK------------KKKKKQHKKH 233
S++S SE + +E + +KK + + + K+ VK K K+ KK
Sbjct: 401 KKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKD 460
Query: 234 SKKKKKKSGSSHKSR 248
KK KK S K +
Sbjct: 461 EKKGKKDSKKDDKKK 475
Score = 60.5 bits (145), Expect = 1e-09
Identities = 61/255 (23%), Positives = 105/255 (41%), Gaps = 53/255 (20%)
Query: 46 KQLENKKTGSKAL-AEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRS 104
K+ KK GS A E ++ + E K++ E + L S +E+ K+ + ++
Sbjct: 128 KKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQN 187
Query: 105 SSSSSSSDSSSSSSDSEDEEK------------KQGKRRKKKKN---------------- 136
S + S + S DS++ +K K+ +R K N
Sbjct: 188 SKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDF 247
Query: 137 ------------------RSYKSSQSSTHE---SESESKESVKKKKKSKD-ETEKEKDVR 174
R+Y + S + ++ K++ K KKS D E+E KD +
Sbjct: 248 LMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAK 307
Query: 175 SLSKKRKKSY-PDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKH 233
SKK KK+ DDK + +ES E +K +R+ ++++ K K K KKK KK+
Sbjct: 308 KDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLK-KDDKKKDTKKY 366
Query: 234 SKKKKKKSGSSHKSR 248
+ +SG + +R
Sbjct: 367 PESTDTESGDAKDAR 381
Score = 60.1 bits (144), Expect = 2e-09
Identities = 51/194 (26%), Positives = 100/194 (51%), Gaps = 23/194 (11%)
Query: 66 NENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSS-SSDSSSSSSDSEDE- 123
N++ KK+ +K S +E SK+ ++ +K+ KK ++ + S +D S+ +DSE +
Sbjct: 393 NDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKG 452
Query: 124 -------EKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKK-KKKSKDETEKEKDVRS 175
++K+GK+ KK ++ K ++ + +E ES +KK KK SK++ +KD++
Sbjct: 453 DSKKGKKDEKKGKKDSKKDDKK-KDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKK 511
Query: 176 LSKKRKKSYPDDKPLSSES---------SSESDYEEDVQ---AKKKRRCEEREQAKEKVK 223
++K +S + SS++ S+++ EE + AKKK + A K++
Sbjct: 512 DARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKME 571
Query: 224 KKKKKQHKKHSKKK 237
+ K+ + S KK
Sbjct: 572 GLESKRGFRMSSKK 585
Score = 48.5 bits (114), Expect = 5e-06
Identities = 43/180 (23%), Positives = 83/180 (46%), Gaps = 7/180 (3%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101
++ KK ++ KT +K + +E E+ + E + + K++ KK KKK
Sbjct: 420 KDEKKDKKDSKTDNKKSVKNDE---ESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKD 476
Query: 102 CRSSSSSSSSDSS-SSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKK 160
+ ++ S+ +S D + ++K+G ++ KK+ + K ++S+ E + SK K
Sbjct: 477 AKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKD-ARKDTESTDAEFDESSKTGFKTS 535
Query: 161 KKSK-DETEKEKDVRSLSKKRKKSYPDDKPLSSESSS-ESDYEEDVQAKKKRRCEEREQA 218
K K +TE E+ + K+K D +S+ ES + +KK E+ E+A
Sbjct: 536 TKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKA 595
Score = 45.1 bits (105), Expect = 6e-05
Identities = 49/210 (23%), Positives = 85/210 (40%), Gaps = 23/210 (10%)
Query: 46 KQLENKKTGSKALAEFEEKMNENWKKELEKSREKL---LSGNESSSKKRERKKKRKKKSC 102
+ L KT K AE+++ +E L+K +K + N S + E K KR+ ++
Sbjct: 101 RHLYTSKTHLKK-AEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEA- 158
Query: 103 RSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKK 162
D + S E+E+ K+ K + S S S + S+ + K+S KK
Sbjct: 159 ---------DKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKT 209
Query: 163 SKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDY--------EEDVQAKKKRRCEE 214
+ + + + + K+ K S + SE+S D+ +E + R
Sbjct: 210 NTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYS 269
Query: 215 REQAKEKVKKKKKKQHKKHSKKKKKKSGSS 244
+ +K K K KK +KK KKS +
Sbjct: 270 QNNSK-NYSLKYTKYTKKDTKKNAKKSSDA 298
Score = 38.5 bits (88), Expect = 0.005
Identities = 41/149 (27%), Positives = 63/149 (42%), Gaps = 8/149 (5%)
Query: 46 KQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSS 105
K+ + KK K E + + KK+ + S+EK G++ KK RK +
Sbjct: 469 KKDDKKKDAKKNAESTEMESDLELKKDKKHSKEK--KGSKKDIKKDARKDTESTDAEFDE 526
Query: 106 SSSSSSDSSS--SSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVK---KK 160
SS + +S+ SD+E EE KKK + S +S +S E ESK + KK
Sbjct: 527 SSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEG-LESKRGFRMSSKK 585
Query: 161 KKSKDETEKEKDVRSLSKKRKKSYPDDKP 189
++ EK R + K P +P
Sbjct: 586 TTFNEKGEKASTGRVPPSREKPPLPACEP 614
Score = 36.2 bits (82), Expect = 0.027
Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 16/112 (14%)
Query: 144 SSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSY---PDDKPLSSESSSESDY 200
S TH ++E KK K K T +KD SKK+ SY P+ K + E + +
Sbjct: 106 SKTHLKKAE----YKKSKDEKGGTPLKKD----SKKKGGSYATNPESKQIVEEKTKRQNE 157
Query: 201 EEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKH-----SKKKKKKSGSSHKS 247
+ K E+ +++K + + Q+ K S+K KK S +S K+
Sbjct: 158 ADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKT 209
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 73.2 bits (178), Expect = 2e-13
Identities = 61/187 (32%), Positives = 93/187 (49%), Gaps = 33/187 (17%)
Query: 42 EEVKKQLENKKT--GSKALAEFEEKMNENWKKELEKSREKLLSGNE--SSSKKRERKKKR 97
+EV +++EN+KT SK AE ++LS E SK ++ +KKR
Sbjct: 148 QEVVREIENQKTDAASKPFAEV-----------------RILSCGELIPKSKVKKEEKKR 190
Query: 98 KKKSCRSSSSSSSSDSSS---SSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESK 154
K S SSSSSS SDSSS SSSDS D E ++ KK+K + K+S+ + K
Sbjct: 191 HKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR--------KHK 242
Query: 155 ESVKKKKKSKDETEKEKDVRSLSKKRKKSY-PDDKPLSSESSSESDYEEDVQAKKKRRCE 213
+ KK+KKSK E + +L + + + P++ P E+ +K+R+
Sbjct: 243 KEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNR 302
Query: 214 EREQAKE 220
ERE+ +E
Sbjct: 303 ERERERE 309
Score = 70.9 bits (172), Expect = 1e-12
Identities = 48/187 (25%), Positives = 95/187 (50%), Gaps = 6/187 (3%)
Query: 68 NWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQ 127
+W++E+++++ +S E K + + K++ RS + + SE +K
Sbjct: 361 HWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKN 420
Query: 128 GKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKR--KKSYP 185
K +K K ++S + SE + K K KK++K ++ + +S SK+R K +
Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN 480
Query: 186 DDKPLSSESSS---ESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHK-KHSKKKKKKS 241
++K + S S E+ E++ Q+ K + +ER ++KEK K+ + K ++ HSK K+K
Sbjct: 481 EEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDR 540
Query: 242 GSSHKSR 248
+ +SR
Sbjct: 541 RAQSRSR 547
Score = 65.5 bits (158), Expect = 4e-11
Identities = 48/206 (23%), Positives = 91/206 (44%), Gaps = 15/206 (7%)
Query: 49 ENKKTGSKALAEFEEKMNENWKKELE---KSREKLLSGN-ESSSKKRERKKKRKKKSCRS 104
E K T + ++E + NE KK + S+E+ + N E K + + KKR K RS
Sbjct: 403 ERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRS 462
Query: 105 SSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSK 164
S S S + +EEK+ R K + + + K + + +S+ + +E + K+KSK
Sbjct: 463 KSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQS-DSKGKDQERSRSKEKSK 521
Query: 165 D----------ETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEE 214
KEKD R+ S+ R+ K + + E D + + R +
Sbjct: 522 QLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHD 581
Query: 215 REQAKEKVKKKKKKQHKKHSKKKKKK 240
R++++ K + ++Q + + + +
Sbjct: 582 RDRSRSKEYHRYREQEYRRRGRSRSR 607
Score = 63.9 bits (154), Expect = 1e-10
Identities = 60/246 (24%), Positives = 120/246 (48%), Gaps = 27/246 (10%)
Query: 18 RWRGPTQSVGPTIQDYLNRPR--PTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEK 75
R+R P++S +D R P W + ++ + + S +K N KE ++
Sbjct: 340 RYRTPSRSRS---RDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQR 396
Query: 76 S----REKLLSGN----ESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQ 127
S +E+ ++ + ES ++K E++KK K S+S +S+ +D+ K +
Sbjct: 397 SPVRVKERKITDHRNVSESPNRKNEKEKKVK-----DHKSNSKERDIRRNSEKDDKYKNK 451
Query: 128 GKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKD-----ETEKEKDVRSLSKKRKK 182
K+R K K+RS +S + E +S+ + +K+ +S+ E KEK+ +S SK + +
Sbjct: 452 VKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQ 511
Query: 183 SYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSG 242
K S + S+S+ + ++K+K R R Q++ + K +H ++ + +++S
Sbjct: 512 ERSRSKEKSKQLESKSNEHDHSKSKEKDR---RAQSRSRECDITKGKH-SYNSRTRERSR 567
Query: 243 SSHKSR 248
S +SR
Sbjct: 568 SRDRSR 573
Score = 62.8 bits (151), Expect = 3e-10
Identities = 58/228 (25%), Positives = 95/228 (41%), Gaps = 29/228 (12%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKK-K 100
E + + ++K+ SK+ K E ++ +SRE ++ + S R R++ R + +
Sbjct: 512 ERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDR 571
Query: 101 SCRSSSSSSSSDSSSSS---------------SDSEDEEKKQGKRRKKKKNRSYKSSQSS 145
S R S + D S S S S + G+ R K + R + S+SS
Sbjct: 572 SRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSS 631
Query: 146 THE-SESESKESVK----KKKKSKDETEKEKDVRSLSK--------KRKKSYPDDKPLSS 192
E S+S +K+ + K K+ +E EK + S S+ + KK+ D P S
Sbjct: 632 EREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSK 691
Query: 193 ESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKK 240
S D E K + E+ + EK +K K Q H +K KK
Sbjct: 692 IKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKK 739
Score = 55.1 bits (131), Expect = 6e-08
Identities = 47/219 (21%), Positives = 96/219 (43%), Gaps = 13/219 (5%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEK----------SREKLLSGNESSSKKR 91
EE+ EN+ K+ + +EK +N ++E E+ S ++ L S K +
Sbjct: 275 EEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIK 334
Query: 92 ERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESES 151
R +R + RS S S + ++ ++ Q + R R K +S +E +
Sbjct: 335 GRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQ-RMRVSSGERWIKGDKSELNEIKE 393
Query: 152 ESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRR 211
+ V+ K++ + + + +++K D K S E + E+D + K K +
Sbjct: 394 NQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVK 453
Query: 212 CEEREQAKEKVKKKKKKQHK--KHSKKKKKKSGSSHKSR 248
+ +++ K K+K K + + KH++ ++K+ S K R
Sbjct: 454 KRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGR 492
Score = 55.1 bits (131), Expect = 6e-08
Identities = 45/214 (21%), Positives = 87/214 (40%), Gaps = 11/214 (5%)
Query: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLS------GNESSSKKRERKKK 96
E K+ K + +EK +++ K+ E+SR K S NE K + K +
Sbjct: 481 EEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDR 540
Query: 97 RKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKES 156
R + R + S +S + E + R ++ ++R++ +S + E ++
Sbjct: 541 RAQSRSRECDITKGKHSYNSRT---RERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE 597
Query: 157 VKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSS--ESDYEEDVQAKKKRRCEE 214
+++ +S+ + RS SK R++ D + E S D + ++K R E
Sbjct: 598 YRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657
Query: 215 REQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
E K K + +S++KK S S+
Sbjct: 658 SESEKRMYSKSRDHNSSNNSREKKADRDQSPFSK 691
Score = 53.1 bits (126), Expect = 2e-07
Identities = 45/223 (20%), Positives = 98/223 (43%), Gaps = 26/223 (11%)
Query: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELE-KSREKLLSGNESSSKKRERKKKRKKKS 101
E +K++++ K+ SK E + N +K+ + K++ K + ++S SK +E+ K +++ S
Sbjct: 421 EKEKKVKDHKSNSK-----ERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDS 475
Query: 102 CRSSSSSSSSDSSSSSSDSE---DEEKKQGKR-----RKKKKNRSYKSSQSSTHESESES 153
+ + S S D E ++EK+ + R + K +S + S S+S
Sbjct: 476 KHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKS 535
Query: 154 KE------------SVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYE 201
KE + K K S + +E+ +R +S D+ S E
Sbjct: 536 KEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYRE 595
Query: 202 EDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSS 244
++ + + + R ER + + K +++ ++ S+ +++ S
Sbjct: 596 QEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQS 638
Score = 50.4 bits (119), Expect = 1e-06
Identities = 34/101 (33%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Query: 148 ESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207
++++ SK + + S E + V+ KKR KS SS SSS+SD D Q+
Sbjct: 158 KTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSS----SSSSSSDSDSSSDSQSS 213
Query: 208 KKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
+ E A E+ KK+KK+H+K+S+K KK+ KS+
Sbjct: 214 SDS--SDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSK 252
Score = 48.5 bits (114), Expect = 5e-06
Identities = 46/167 (27%), Positives = 71/167 (42%), Gaps = 15/167 (8%)
Query: 83 GNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKS- 141
G S ++ R+ + +K S + S + + KK+ K+R K + S S
Sbjct: 142 GQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSS 201
Query: 142 --------SQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSE 193
SQSS+ S+SES K KK+ K + + + KKRKKS K SSE
Sbjct: 202 SDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKS---KKSASSE 258
Query: 194 SSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKK 240
S +E+ + Q + R EE E +K K K++K +
Sbjct: 259 SEAEN---LEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNR 302
Score = 45.4 bits (106), Expect = 4e-05
Identities = 49/271 (18%), Positives = 108/271 (39%), Gaps = 77/271 (28%)
Query: 53 TGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSD 112
+ S + + + +E+ +E K R+K N KK ++K+K+ KKS S S + + +
Sbjct: 206 SSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLE 265
Query: 113 SSSSSS--------------------DSEDEEKKQGKRRKKKKNRSYKSSQSSTHE---- 148
+ S+ DE++++ + R++++ + +SQ ++++
Sbjct: 266 AQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLL 325
Query: 149 -------------------SESESKESVKKK-------------------------KKSK 164
S S S++ ++ K K
Sbjct: 326 VTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDK 385
Query: 165 DE-TEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKK--------KRRCEER 215
E E +++ RS + +++ D + +S + +++ E+ V+ K +R E+
Sbjct: 386 SELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKD 445
Query: 216 EQAKEKVKKKKKKQHKKHSKKKKKKSGSSHK 246
++ K KVKK+ K + + SK+K K K
Sbjct: 446 DKYKNKVKKRAKSKSRSKSKEKSKSKERDSK 476
Score = 44.3 bits (103), Expect = 1e-04
Identities = 24/80 (30%), Positives = 41/80 (51%)
Query: 162 KSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEK 221
KSK + E++K +S S S D S+SSS+S E +K ++ +++ + +
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239
Query: 222 VKKKKKKQHKKHSKKKKKKS 241
KK+KK+ KK K +S
Sbjct: 240 KHKKEKKKRKKSKKSASSES 259
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 72.4 bits (176), Expect = 3e-13
Identities = 57/204 (27%), Positives = 92/204 (45%), Gaps = 42/204 (20%)
Query: 41 WEEVKKQLENKKTGSKALAEFEEK-MNENWKKELEKSREKLLSGNESSSKKRERKKKRKK 99
WE+++++ + E E K + +++ LE + S N+ SKK KK +
Sbjct: 740 WEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKK---SKKHHR 796
Query: 100 KSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKK 159
K RS S S S D S S KKK+ RS +S +S H S +ES+ S KK
Sbjct: 797 KRSRSRSGSDSDDDDSHS--------------KKKRQRS-ESRSASEHSSSAESERSYKK 841
Query: 160 KKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAK 219
KK K K +K+ + D P E D + +K ++ ++RE K
Sbjct: 842 SKKHK------------KKSKKRRHKSDSP-----------ESDAEREKDKKEKDRESEK 878
Query: 220 EKVKKKKKKQHKKHSKKKKKKSGS 243
++ +++ + +HK KK K SG+
Sbjct: 879 DRTRQRSESKHKSPKKKTGKDSGN 902
Score = 49.3 bits (116), Expect = 3e-06
Identities = 44/203 (21%), Positives = 80/203 (39%), Gaps = 23/203 (11%)
Query: 68 NWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSS----------------- 110
N K EK + K+ RK KRK+ + +S ++
Sbjct: 689 NIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFV 748
Query: 111 SDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKE 170
+ + E E K+ K + S + +SK+ +K+ +S+ ++ +
Sbjct: 749 KEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSD 808
Query: 171 KDVRSLSKKRKKSYP-DDKPLSSESSSESDYEEDVQAKKK-----RRCEEREQAKEKVKK 224
D KKR++S SS + SE Y++ + KKK + + E E+ K
Sbjct: 809 DDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKD 868
Query: 225 KKKKQHKKHSKKKKKKSGSSHKS 247
KK+K + + +++S S HKS
Sbjct: 869 KKEKDRESEKDRTRQRSESKHKS 891
Score = 38.5 bits (88), Expect = 0.005
Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 32/143 (22%)
Query: 46 KQLENKKTGSKALAEFEEKMNENWKK----------ELEKSREKLLSGNESSSKKRERKK 95
K+ K++ S++ ++ ++ + + KK E S E S +S K++ KK
Sbjct: 792 KKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKK 851
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKE 155
+R K S S SD+E E+ K+ K R+ +K+R+ SESK
Sbjct: 852 RRHK-------------SDSPESDAEREKDKKEKDRESEKDRT---------RQRSESKH 889
Query: 156 SVKKKKKSKDETEKEKDVRSLSK 178
KKK KD + LS+
Sbjct: 890 KSPKKKTGKDSGNWDTSGSELSE 912
Score = 33.5 bits (75), Expect = 0.18
Identities = 30/137 (21%), Positives = 66/137 (48%), Gaps = 11/137 (8%)
Query: 113 SSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVK---KKKKSKDETEK 169
SS++ ++ +E KK++ S + ++ T ++ E+K++ K K+K+
Sbjct: 329 SSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASW 388
Query: 170 EKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQ 229
E+ ++ + + Y LS + + + Y+ VQ +K EE+E+A+ K K+ K+
Sbjct: 389 EQAMKMIINDPR--YSALAKLSEKKQAFNAYK--VQTEK----EEKEEARSKYKEAKESF 440
Query: 230 HKKHSKKKKKKSGSSHK 246
+ +K S + +K
Sbjct: 441 QRFLENHEKMTSTTRYK 457
Score = 30.8 bits (68), Expect = 1.1
Identities = 43/206 (20%), Positives = 89/206 (43%), Gaps = 24/206 (11%)
Query: 40 TWEEVKKQLENKKTGSKALAEFEEKMN-------ENWKKELEKSREKLLSGNESSSKKRE 92
+WE+ K + N S ALA+ EK + K+E E++R K ES + E
Sbjct: 387 SWEQAMKMIINDPRYS-ALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLE 445
Query: 93 RKKK-----RKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTH 147
+K R KK+ + ++ S E E KK+K ++ K +
Sbjct: 446 NHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQA-KQLRKRNW 504
Query: 148 ESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSES--DYEEDVQ 205
E+ +++ S +E ++ + ++ +D+ L + ++ +EE ++
Sbjct: 505 EALKNILDNMANVTYSTTWSEAQQYLMD-----NPTFAEDEELQNMDKEDALICFEEHIR 559
Query: 206 AKKKRRCEEREQAKEKVKKKKKKQHK 231
A +K EE E+ ++ + +++++Q K
Sbjct: 560 ALEK---EEEEEKQKSLLRERRRQRK 582
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 72.0 bits (175), Expect = 4e-13
Identities = 57/237 (24%), Positives = 98/237 (41%), Gaps = 23/237 (9%)
Query: 18 RWRGPTQSVGPTIQDYLNRPRPTWEE------VKKQLENKKTGSKALAEFEEKMNENWKK 71
R R P +S+ P +R R E ++LE +K E + E K
Sbjct: 259 RSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREK---------ERQRLEREAK 309
Query: 72 ELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRR 131
E EK R + S + ++R R ++R + S S S D D D E+++ R
Sbjct: 310 EREKERRRSRSIDRGLERRRSRSRERHR------SRSRSRDRKGDRRD-RDREREKENER 362
Query: 132 KKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKR-KKSYPDDKPL 190
++++R Y + + E E E K+++S+ E E++K +R + D K
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKE 422
Query: 191 SSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247
S S S + + R +R +++ K K K K K K+ +SGS ++
Sbjct: 423 KKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRT 479
Score = 66.6 bits (161), Expect = 2e-11
Identities = 40/173 (23%), Positives = 85/173 (49%), Gaps = 4/173 (2%)
Query: 70 KKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGK 129
+KE E+ R + ++ +RE++++R ++ + S + D +D + K
Sbjct: 357 EKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDK 416
Query: 130 R-RKKKKNRSYKSSQSSTHESESESKESVKK-KKKSKDETEKEK-DVRSLSKKRKKSYPD 186
R KK+K S S+ H S S S+ + K+ + +SK+++ K K + + S KR +S
Sbjct: 417 RDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQ 476
Query: 187 DKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
+ S E S + ++ + K ++R +E++ ++ K Q KH +++ +
Sbjct: 477 GRTDSVEKSKKREHSPS-KEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQ 528
Score = 64.3 bits (155), Expect = 9e-11
Identities = 56/255 (21%), Positives = 109/255 (42%), Gaps = 34/255 (13%)
Query: 21 GPTQSVGPTIQDYLNR-----------PRPTWEEVKKQLENKKTGSKALAEFEEKMNENW 69
G ++G ++ +L + P P + + +Q+ KT + + + ++ E
Sbjct: 195 GCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQI---KTRPRKIKKDGKEGAEEI 251
Query: 70 KKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGK 129
+ +E+ R + S S S +R ++ R + R SSS D +++ K
Sbjct: 252 DRHVERRRSR--SPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAK 309
Query: 130 RRKKKKNRSY---------KSSQSSTHESESESKESVKKKKKSKDETEKEKDV-----RS 175
R+K++ RS +S H S S S++ ++ E EKE + R
Sbjct: 310 EREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRD 369
Query: 176 LSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSK 235
K+R ++ S E S E +V+ KK + E+++ + + K+ K+ KKHS+
Sbjct: 370 YDKERGNEREKERERSRERSKEQRSRGEVEEKKHK--EDKDDRRHRDDKRDSKKEKKHSR 427
Query: 236 KK--KKKSGSSHKSR 248
+ ++K S +SR
Sbjct: 428 SRSRERKHRSRSRSR 442
Score = 64.3 bits (155), Expect = 9e-11
Identities = 48/192 (25%), Positives = 91/192 (47%), Gaps = 11/192 (5%)
Query: 45 KKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRS 104
+++ EN++ G + +++++ +KE E+SRE+ S + E+K K K R
Sbjct: 355 EREKENER-GRRRDRDYDKERGNEREKERERSRER-SKEQRSRGEVEEKKHKEDKDDRRH 412
Query: 105 SSSSSSSDSSSSSSDSEDEEKKQGKRRKK----KKNRSYKSSQSSTHESESESKESVKKK 160
S S S E+K R + K++RS +SS H++ES+ K +
Sbjct: 413 RDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSN---- 468
Query: 161 KKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEED-VQAKKKRRCEEREQAK 219
K+S+ ++ D SKKR+ S +K S E ++ D +K + +R +++
Sbjct: 469 KRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQ 528
Query: 220 EKVKKKKKKQHK 231
++ ++KQHK
Sbjct: 529 SIEQESQEKQHK 540
Score = 57.0 bits (136), Expect = 1e-08
Identities = 45/194 (23%), Positives = 85/194 (43%), Gaps = 15/194 (7%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95
R R +E + E ++ S+ ++ + E +K+ ++ ++ ++ K+E+K
Sbjct: 366 RDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKH 425
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKE 155
R + R S S S ++ S S +EK K KN S + S + +
Sbjct: 426 SRSRSRERKHRSRSRSRNAGKRSRSRSKEKS-----SKHKNESKEKSNKRSRSGSQGRTD 480
Query: 156 SVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEER 215
SV+K KK + KEK R S+ +++S+ D S + S + D +RR +
Sbjct: 481 SVEKSKKREHSPSKEKS-RKRSRSKERSHKRDHSDSKDQSDKHD---------RRRSQSI 530
Query: 216 EQAKEKVKKKKKKQ 229
EQ ++ + K K +
Sbjct: 531 EQESQEKQHKNKDE 544
Score = 51.6 bits (122), Expect = 6e-07
Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 21/137 (15%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERK 94
+R R + + + ++ G ++ + +EK +++ + EKS ++ SG++ + E+
Sbjct: 426 SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKS 485
Query: 95 KKRK----KKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESE 150
KKR+ K+ R S S SDS+D+ K +RR S+
Sbjct: 486 KKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRR-----------------SQ 528
Query: 151 SESKESVKKKKKSKDET 167
S +ES +K+ K+KDET
Sbjct: 529 SIEQESQEKQHKNKDET 545
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 71.6 bits (174), Expect = 6e-13
Identities = 42/204 (20%), Positives = 102/204 (50%), Gaps = 12/204 (5%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95
R R + +++ + K+T E + ++ + ++E +K RE+ ++RER +
Sbjct: 92 RDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER----ERDRGRERERDR 147
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKE 155
R+K+ R + + + D E+++ K R+ +++R + E +++ +
Sbjct: 148 DREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRER 207
Query: 156 SVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEER 215
++K +++ + E +++ + +R++ D + E D E D +K+ R +ER
Sbjct: 208 DRQRKTQTERQRETDREGERETDRRRERQRD-----RDRGKERDRERD---RKEERKKER 259
Query: 216 EQAKEKVKKKKKKQHKKHSKKKKK 239
++ ++K +K+KKK+ K+ KK+K
Sbjct: 260 KKERKKERKEKKKEEKRREDKKRK 283
Score = 70.9 bits (172), Expect = 1e-12
Identities = 42/196 (21%), Positives = 99/196 (50%), Gaps = 18/196 (9%)
Query: 70 KKELEKSREKLLSGNESSSKKRERKKKRKKKSC-----RSSSSSSSSDSSSSSSDSEDEE 124
++E ++ REK +KR+R+++RK+K R + D + E
Sbjct: 78 QRERDRVREKT-EKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERE 136
Query: 125 KKQGKRRK------KKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSK 178
+ +G+ R+ K++ R + + E+E+E + +++K+ + ETE+++D + ++
Sbjct: 137 RDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTE 196
Query: 179 KRKKSYPD-----DKPLSSESSSESDYEEDVQAKKKR-RCEEREQAKEKVKKKKKKQHKK 232
K ++ D + +E E+D E + + ++R R +R++ KE+ +++ +K+ +K
Sbjct: 197 KERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERK 256
Query: 233 HSKKKKKKSGSSHKSR 248
+KK++K K +
Sbjct: 257 KERKKERKKERKEKKK 272
Score = 69.7 bits (169), Expect = 2e-12
Identities = 42/209 (20%), Positives = 102/209 (48%), Gaps = 15/209 (7%)
Query: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC 102
E ++ + K+ + E E N + +K+ E R++ + ++R+R ++R++
Sbjct: 89 EKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRD 148
Query: 103 RSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKK- 161
R ++ + E+++ + R+K+K R + + ++E E + +++
Sbjct: 149 REKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD 208
Query: 162 -KSKDETEKEKDV-----RSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEER 215
+ K +TE++++ R ++R++ D+ E D E D K++R+ E +
Sbjct: 209 RQRKTQTERQRETDREGERETDRRRERQRDRDR------GKERDRERD--RKEERKKERK 260
Query: 216 EQAKEKVKKKKKKQHKKHSKKKKKKSGSS 244
++ K++ K+KKK++ ++ KK+K G S
Sbjct: 261 KERKKERKEKKKEEKRREDKKRKWGEGIS 289
Score = 48.5 bits (114), Expect = 5e-06
Identities = 26/158 (16%), Positives = 79/158 (50%), Gaps = 16/158 (10%)
Query: 85 ESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQS 144
+ ++RER + R+K + D + + ++ +R++K+ NR+ + +
Sbjct: 73 DGDDRQRERDRVREK--------------TEKERDRDRKRDRERRRKEKETNRN-RDREK 117
Query: 145 STHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDV 204
T +E K +++ +D + + R K+R++ D+ E+ +E + + +
Sbjct: 118 QTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRER 177
Query: 205 QAKKKRRCE-EREQAKEKVKKKKKKQHKKHSKKKKKKS 241
+ +K+R E +R++ ++ K+++++ ++ +++K ++
Sbjct: 178 EKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQT 215
Score = 42.7 bits (99), Expect = 3e-04
Identities = 22/145 (15%), Positives = 65/145 (44%), Gaps = 1/145 (0%)
Query: 104 SSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKS 163
S S S + D++ +++++ + R ++K + ++ + +
Sbjct: 56 SQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDR 115
Query: 164 KDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVK 223
+ +TE E+D R K++ + D+ E + + E + Q +K R + + + +
Sbjct: 116 EKQTEIERD-REREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERD 174
Query: 224 KKKKKQHKKHSKKKKKKSGSSHKSR 248
++++KQ ++ +++ + + + K R
Sbjct: 175 REREKQKERETERDRDRQRDTEKER 199
Score = 29.6 bits (65), Expect = 2.5
Identities = 21/127 (16%), Positives = 62/127 (48%), Gaps = 21/127 (16%)
Query: 127 QGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPD 186
+G+ ++ RS+ Q+ +++ + ++ + + + K E E+++D + ++R+K
Sbjct: 51 RGRLGSQESPRSWGLGQAHK-DADGDDRQRERDRVREKTEKERDRDRKRDRERRRKE--- 106
Query: 187 DKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKK-----KQHKKHSKKKKKKS 241
E++ D E+ + ER++ +EK K +++ ++ ++ ++K++
Sbjct: 107 -----KETNRNRDREKQTEI-------ERDREREKQKGRERERDRGRERERDRDREKERE 154
Query: 242 GSSHKSR 248
+ K R
Sbjct: 155 RQTEKDR 161
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 70.1 bits (170), Expect = 2e-12
Identities = 37/197 (18%), Positives = 97/197 (49%), Gaps = 7/197 (3%)
Query: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC 102
E K++ + K + E+ N+ ++ + R++ + + +++ER++++++
Sbjct: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQ 65
Query: 103 RSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKK 162
R + ++ E+K+ R++ K+R + + + E K ++ K+
Sbjct: 66 RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQ 125
Query: 163 SKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKV 222
++ E ++E++ R++ ++ E E+D E A+++ R +ER++ ++K
Sbjct: 126 TERERDRERE-------RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
Query: 223 KKKKKKQHKKHSKKKKK 239
+K+KKK+ K+ KK+K
Sbjct: 179 RKEKKKEEKRREDKKRK 195
Score = 65.1 bits (157), Expect = 5e-11
Identities = 38/196 (19%), Positives = 95/196 (48%), Gaps = 23/196 (11%)
Query: 73 LEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRK 132
+E+ RE+ + +RER ++R++++ + D + + +K+ + R+
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKE-RERQ 59
Query: 133 KKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKD-----VRSLSKKRKKSYPDD 187
K+++R + + + E+E + + ++++K + + E++KD R + R+++
Sbjct: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 188 KPLSSESSSESDYEEDVQAKKKR-----------------RCEEREQAKEKVKKKKKKQH 230
+ ++ E D E + Q +++R R ERE+ K++ KK++KK+
Sbjct: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
Query: 231 KKHSKKKKKKSGSSHK 246
K+ K++K++ K
Sbjct: 180 KEKKKEEKRREDKKRK 195
Score = 55.8 bits (133), Expect = 3e-08
Identities = 30/151 (19%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95
R R T E +++ + ++ + E+ E ++E ++ RE+ + K R+R++
Sbjct: 46 RDRQTDREKERERQKERDRQRQRERETERETER-QRERQRQRERKRQTDRERDKDRDRER 104
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHE----SES 151
KR+ R + + + D E+++ ++R++++ R + + + E +E
Sbjct: 105 KRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAER 164
Query: 152 ESKESVKKKKKSKDETEKEKDVRSLSKKRKK 182
E ++ +KK++ K+ EK+K+ + K++K
Sbjct: 165 EERKKERKKERKKERKEKKKEEKRREDKKRK 195
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 69.7 bits (169), Expect = 2e-12
Identities = 50/219 (22%), Positives = 113/219 (51%), Gaps = 16/219 (7%)
Query: 31 QDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNE-SSSK 89
+D ++R + + K+LE +K G K E E + E ++E E+ RE+ E +
Sbjct: 274 RDLISREISKFRDTHKKLEEEK-GKK---EKERQEIEKERRERERERERERERRERERER 329
Query: 90 KRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHES 149
+RER+++++K+ R D + D E+ + + R++ +R+ S+S
Sbjct: 330 EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389
Query: 150 ESESKESVKKKKKSKDETEKEKD-VRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKK 208
+ E + +++++ + E E+E++ R ++R++ DK E E YE + K
Sbjct: 390 DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYE---RRKL 446
Query: 209 KRRCEEREQA-KEKVK------KKKKKQHKKHSKKKKKK 240
+R+ E+E A +E++K +KK ++++K +++++++
Sbjct: 447 ERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 485
Score = 68.2 bits (165), Expect = 6e-12
Identities = 51/195 (26%), Positives = 97/195 (49%), Gaps = 14/195 (7%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERK--KKRKK 99
E +++ E ++ + E E + +KE E+ RE+ + +K+R+R ++R +
Sbjct: 308 ERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDR 367
Query: 100 KSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKK 159
R SS + D S S S D E+++ + R++++ R + + E E E +E ++
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERE-RERERE 426
Query: 160 KKKSKDETEKEKDV---RSLSKK-RKKSYPDDKPLSS----ESSSESDYEEDVQAKKKRR 211
K K +D E E+D R L +K R+K + L + E +YE++ + +++RR
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486
Query: 212 CEEREQAKEKVKKKK 226
RE AKE + K+
Sbjct: 487 ---REMAKEAKRLKE 498
Score = 60.5 bits (145), Expect = 1e-09
Identities = 39/190 (20%), Positives = 92/190 (48%), Gaps = 7/190 (3%)
Query: 55 SKALAEFEE--KMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC-RSSSSSSSS 111
S+ +++F + K E K + EK R+++ ++RER+++R+++ R
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337
Query: 112 DSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEK 171
+ D ++ + K R + ++R + S +K+ + ++KS+D + +
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRE-RDRDRDRERSSDRNKDRSRSREKSRDRERERE 396
Query: 172 DVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHK 231
R ++R++ ++ E E + E+D KK+ R E+ E A E+ K ++K + K
Sbjct: 397 REREREREREREREREREREREREREREREKD---KKRDREEDEEDAYERRKLERKLREK 453
Query: 232 KHSKKKKKKS 241
+ + +++ K+
Sbjct: 454 EAAYQERLKN 463
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/206 (20%), Positives = 96/206 (46%), Gaps = 34/206 (16%)
Query: 72 ELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRR 131
+L+ +KLL ++ +K + + K KKK+ S+ ++ + ++D E+ ++ KRR
Sbjct: 149 DLQIGEKKLLVKVDAKTKAQLDEWKAKKKA-----SNGNARPETVTNDDEEALDEETKRR 203
Query: 132 KKKKNRSYK------SSQSSTHESESESKESVKKKKKSKD-------------------- 165
+ + + SS+ + ES+S KKK+K +D
Sbjct: 204 DQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKED 263
Query: 166 --ETEKEKDVRSLSKKRKKSYPDD-KPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKV 222
E E+D R L + + D K L E + ++++ +++ R ERE+ +E+
Sbjct: 264 INAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERR 323
Query: 223 KKKKKKQHKKHSKKKKKKSGSSHKSR 248
+++++++ ++ +K+K++ + R
Sbjct: 324 EREREREREREREKEKERERERERDR 349
Score = 53.1 bits (126), Expect = 2e-07
Identities = 35/171 (20%), Positives = 78/171 (45%), Gaps = 14/171 (8%)
Query: 72 ELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRR 131
E+E+ + L+S SK R+ KK +++ + + + E E +++ + R
Sbjct: 268 EMEEDKRDLIS--REISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRER 325
Query: 132 KKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLS 191
++++ R + + E E E + K+ + ++E+D R ++R D+ S
Sbjct: 326 EREREREREREKEKERERERERDRDRDRTKERDRDRDRERD-RDRDRERSSDRNKDRSRS 384
Query: 192 SESSSESDYEEDVQAKKKRRCE-----------EREQAKEKVKKKKKKQHK 231
E S + + E + + +++R E ERE+ +E+ K KK+ + +
Sbjct: 385 REKSRDREREREREREREREREREREREREREREREREREREKDKKRDREE 435
Score = 51.2 bits (121), Expect = 8e-07
Identities = 36/180 (20%), Positives = 82/180 (45%), Gaps = 6/180 (3%)
Query: 66 NENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSD-SSSSSSDSEDEE 124
N++ + EKSR++ ++RER+++R+++ R + D E++E
Sbjct: 378 NKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDE 437
Query: 125 KKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSK--KRKK 182
+ +RRK ++ K + E +E K ++ K+ +E+ R ++K KR K
Sbjct: 438 EDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLK 497
Query: 183 SYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSG 242
+ +D + + Y +K+ R E+E ++ +K++K+ + +++ G
Sbjct: 498 EFLED---YDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEG 554
Score = 49.3 bits (116), Expect = 3e-06
Identities = 35/182 (19%), Positives = 91/182 (50%), Gaps = 32/182 (17%)
Query: 60 EFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSD 119
E EE + +E+ K R+ + KK E +K +K+K
Sbjct: 268 EMEEDKRDLISREISKFRD--------THKKLEEEKGKKEK------------------- 300
Query: 120 SEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKK 179
+ ++ + +RR++++ R + + E E E + +K+K+ + E E+++D R +K+
Sbjct: 301 --ERQEIEKERRERERERE-RERERREREREREREREREKEKERERERERDRD-RDRTKE 356
Query: 180 RKKSYPDDKPLSSESSSESDYEED-VQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKK 238
R + ++ + SD +D ++++K R ERE+ +E+ +++++++ ++ ++++
Sbjct: 357 RDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERE 416
Query: 239 KK 240
++
Sbjct: 417 RE 418
Score = 47.4 bits (111), Expect = 1e-05
Identities = 44/226 (19%), Positives = 97/226 (42%), Gaps = 26/226 (11%)
Query: 41 WEEVKKQLENKKTGSKALAEFEEKMNENWKKE------------LEKSREKLLSGNESSS 88
W+ KK + EE ++E K+ E S E ES S
Sbjct: 172 WKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDS 231
Query: 89 KKRERKKKRKKKSCRSSSSSSS------SDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSS 142
R++KK++K+ R + + ++ + E++++ R K ++K
Sbjct: 232 HPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKL 291
Query: 143 QSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEE 202
+ + E E +E K+++ E E+E++ ++R++ ++ E E + E
Sbjct: 292 EEEKGKKEKERQEIEKERR----ERERERERERERREREREREREREREKEKERERERER 347
Query: 203 DVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
D + + R +ER++ +++ ++ + + ++ S + K +S S KSR
Sbjct: 348 D---RDRDRTKERDRDRDR-ERDRDRDRERSSDRNKDRSRSREKSR 389
Score = 46.6 bits (109), Expect = 2e-05
Identities = 42/244 (17%), Positives = 98/244 (40%), Gaps = 41/244 (16%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERK 94
+R R + + E +K + EK + +E E+ RE+ ++RER+
Sbjct: 358 DRDRDRERDRDRDRERSSDRNKDRSRSREKSRD---RERERERERERERERERERERERE 414
Query: 95 KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKK----------------KKNRS 138
++R+++ R D D+ + K + K R+K KK R
Sbjct: 415 REREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTRE 474
Query: 139 YKSSQSSTHESESESKESVKKKKKSKDE--------------------TEKEKDVRSLSK 178
Y+ E E + K+ K+ ++ ++EK++ + +
Sbjct: 475 YEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADER 534
Query: 179 KRKKSYPDDKPLSSESSSESDYEEDVQAKK-KRRCEEREQAKEKVK-KKKKKQHKKHSKK 236
RK+ + + + +E + D + ++ ++ E R Q + K + + ++++ +K K+
Sbjct: 535 DRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKE 594
Query: 237 KKKK 240
+K++
Sbjct: 595 EKRE 598
Score = 42.7 bits (99), Expect = 3e-04
Identities = 32/180 (17%), Positives = 88/180 (48%), Gaps = 15/180 (8%)
Query: 45 KKQLENKKTGSKALAEFEEKMNENWK-KELEKSREKLLSGNESSSKKRERKKKRKKKSCR 103
+++LE K +A ++E++ +NW+ +E +K+RE + + ++ ER+++ K++ R
Sbjct: 443 RRKLERKLREKEAA--YQERL-KNWEIRERKKTREY----EKEAEREEERRREMAKEAKR 495
Query: 104 SSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHE--SESESKESVKKKK 161
D D +D + +G +K+ K ++ + E E E ++++
Sbjct: 496 LKEFLEDYD-----DDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRL 550
Query: 162 KSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEK 221
++ + + +++ + ++ ++ ES E + +++ + K++ EE E+ ++K
Sbjct: 551 LAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 42.4 bits (98), Expect = 4e-04
Identities = 39/224 (17%), Positives = 97/224 (43%), Gaps = 20/224 (8%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSS---KKR 91
+R R E +++ E ++ + E+ E ++E EK +++ +E + +K
Sbjct: 388 SRDRERERERERERERERERERERERERERERER-EREREKDKKRDREEDEEDAYERRKL 446
Query: 92 ERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDE-EKKQGKRR----KKKKNRSYKSSQSST 146
ERK + K+ + + + + + E E E+++ +RR + K+ + +
Sbjct: 447 ERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDD 506
Query: 147 HESESESKESVKKKKKSKDETEKEKDVRSLSKKRK-----------KSYPDDKPLSSESS 195
+ + S +K+ E E E D R ++++ + +PD
Sbjct: 507 RDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRME 566
Query: 196 SESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
E++ Q K++ EE E+ K++ ++K+++ ++ + ++K
Sbjct: 567 QEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 29.6 bits (65), Expect = 2.5
Identities = 37/166 (22%), Positives = 69/166 (41%), Gaps = 23/166 (13%)
Query: 60 EFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSD 119
E E + E K+E E+ RE+ + E +K K + S S SS+S +++ ++
Sbjct: 580 EPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPG 639
Query: 120 SE-----------DEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDET- 167
E +++Q + + K S K S++ SVK+KK D
Sbjct: 640 DESPCGIIIPHENSPDQQQPEEHRPKIGLSLKLGASNS----PGQPNSVKRKKLPVDSVF 695
Query: 168 --EKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRR 211
+++D + +KRK PL ++ + V ++KR+
Sbjct: 696 NKFEDEDSDDVPRKRKL-----VPLDYGEDDKNATKGTVNTEEKRK 736
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 69.3 bits (168), Expect = 3e-12
Identities = 65/225 (28%), Positives = 109/225 (48%), Gaps = 47/225 (20%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKL-LSGNESSSKKRER 93
N P EE K Q+ S++ ++ EE ++ L R KL +S ES +K+ +
Sbjct: 1269 NEENPGDEEAKNQVN-----SESDSDSEESKKPRYRHRL--LRHKLTVSDGESGEEKKTK 1321
Query: 94 KKKRKKKSCRSSSSSSSSDSSSSS----------SDSEDE-------------EKKQGKR 130
K+ K+ R+ SS DS S S+SEDE E+ Q
Sbjct: 1322 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY 1381
Query: 131 RKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEK--------DVRSLSKKRK- 181
++KKK R K + S+ E++S S+E ++K++ ++E E+E+ D +S K RK
Sbjct: 1382 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKK 1441
Query: 182 --KSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKK 224
K DDK L +E+ + EE+ +++R ERE+ +EK+++
Sbjct: 1442 IRKILKDDK-LRTETQNALKEEEE----RRKRIAEREREREKLRE 1481
Score = 67.0 bits (162), Expect = 1e-11
Identities = 55/207 (26%), Positives = 99/207 (47%), Gaps = 7/207 (3%)
Query: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC 102
++++Q E+ G++ L E EE + + K +++ + G + S K R+ K KKK
Sbjct: 966 KMEQQYESSSDGTEKLPEREEICH--FPKGIKQIKNGTTDGEKKSKKIRD--KTSKKKDE 1021
Query: 103 RSSSSSSSSDSSSSSSDSEDEEKKQGK--RRKKKKNRSYKSSQSSTHESESESKESVKKK 160
S + S+ S SED++ K G R KK+ KSS+ S S++++ K+
Sbjct: 1022 LSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKE 1081
Query: 161 KKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKE 220
++ K + ++ S + K + S SSS SD EE + KK++ + K
Sbjct: 1082 DGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSS-SDAEESSEDNKKKKQRTSSKKKA 1140
Query: 221 KVKKKKKKQHKKHSKKKKKKSGSSHKS 247
+ K+KK+ + S K+K+ +S S
Sbjct: 1141 VIVKEKKRNSLRTSTKRKQADITSSSS 1167
Score = 65.1 bits (157), Expect = 5e-11
Identities = 54/205 (26%), Positives = 91/205 (44%), Gaps = 8/205 (3%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLS--GNESSSKKRERKKKRKK 99
EE+K L + + GS E K + E E+ + +ES S E KK R +
Sbjct: 1240 EEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYR 1299
Query: 100 KSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESE-----SESK 154
+ S S ++ +E K+ K R ++K S S S ES SES+
Sbjct: 1300 HRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESE 1359
Query: 155 ESVKKKKKSKDETEKEKDVRSLS-KKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCE 213
+ + + +S + E E++ RS KK+++ + SSE+ S S+ EE+ + +++ E
Sbjct: 1360 DEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEE 1419
Query: 214 EREQAKEKVKKKKKKQHKKHSKKKK 238
E E+ +E K K K +K
Sbjct: 1420 EEEEEEEDENDDSKSPGKGRKKIRK 1444
Score = 58.5 bits (140), Expect = 5e-09
Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 11/153 (7%)
Query: 98 KKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESV 157
KK ++ SSD SS D +E KK+ ++ ++ ++ ES+S+S+ES
Sbjct: 1235 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESK 1294
Query: 158 KKKKK----------SKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207
K + + S E+ +EK + K K + + +SSE S +SD++E ++
Sbjct: 1295 KPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGR-NRRKVSSEDSEDSDFQESGVSE 1353
Query: 208 KKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKK 240
+ E+ ++ + + KK + + + S K+KKK
Sbjct: 1354 EVSESEDEQRPRTRSAKKAELEENQRSYKQKKK 1386
Score = 55.5 bits (132), Expect = 4e-08
Identities = 54/182 (29%), Positives = 80/182 (43%), Gaps = 23/182 (12%)
Query: 46 KQLENKKTG----SKALAEFEEKMNENWKKELEKSREKLLSGNESSSKK-------RERK 94
KQ++N T SK + + K + EKS K S + S KK RE+K
Sbjct: 995 KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK 1054
Query: 95 K-------KRKKKSCRSSSSS--SSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSS 145
+ RK++ C SS + S + +SSD + + +RR R+ K QS
Sbjct: 1055 RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSG 1114
Query: 146 THESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSE--SSSESDYEED 203
+ S++E KKKK + + K+K V KKR K ++ SSS SD E+D
Sbjct: 1115 SSSSDAEESSEDNKKKKQR-TSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDD 1173
Query: 204 VQ 205
Q
Sbjct: 1174 DQ 1175
Score = 46.2 bits (108), Expect = 3e-05
Identities = 48/210 (22%), Positives = 86/210 (40%), Gaps = 19/210 (9%)
Query: 49 ENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSS 108
+N KT + ++ E+ E +E S E + + + + R+R K+++ S +
Sbjct: 828 KNLKTSQEGSSDDAERKQE---RETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVD 884
Query: 109 SSSDSSSSSSDSE----DEEKKQGKRRKKKKNRSYKSSQSSTHE-------SESESKESV 157
S S + E E K++ K K K + + S E S+ S++
Sbjct: 885 KLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDK 944
Query: 158 KKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQ 217
K+ KK +E +K D + K ++ Y SS +E E + + ++ +
Sbjct: 945 KQSKKGTEEKKKPSDFKKKVIKMEQQYE-----SSSDGTEKLPEREEICHFPKGIKQIKN 999
Query: 218 AKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247
+KK KK K SKKK + S + KS
Sbjct: 1000 GTTDGEKKSKKIRDKTSKKKDELSDYAEKS 1029
Score = 46.2 bits (108), Expect = 3e-05
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 18/199 (9%)
Query: 43 EVKKQLENKKTG----SKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRK 98
EV+K E K+ +K + ++ +++ +K L+K + S ++ K+ ++K+K
Sbjct: 897 EVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKK 956
Query: 99 KKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVK 158
+ SSS +E +++ K K ++ T + E K
Sbjct: 957 PSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPK---GIKQIKNGTTDGE-------K 1006
Query: 159 KKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQA 218
K KK +D+T K+KD LS +KS K S +SS + + ++K+RC+ ++
Sbjct: 1007 KSKKIRDKTSKKKD--ELSDYAEKS--TGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKS 1062
Query: 219 KEKVKKKKKKQHKKHSKKK 237
K + +K+S K+
Sbjct: 1063 SRKRQDCSSSDTEKYSMKE 1081
Score = 44.7 bits (104), Expect = 8e-05
Identities = 53/238 (22%), Positives = 94/238 (39%), Gaps = 44/238 (18%)
Query: 32 DYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKR 91
D PR +++ E S + E E + E K + ++ + ++S+
Sbjct: 614 DLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNP 673
Query: 92 ERKKKRKKKSCRSSSSSSSSD------------SSSSSSDSE------------DEEKKQ 127
+ K K K + +S SD S SSSSD++ D + +
Sbjct: 674 KPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQA 733
Query: 128 GK--RRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDET---------EKEKDVRSL 176
GK + K+K+ S S T + +S + KKK+ +T E EK+++S+
Sbjct: 734 GKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKR---QTQSESSNYDSELEKEIKSM 790
Query: 177 SK-----KRKKSYPDDKPL-SSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKK 228
SK KK P+ K SSE S D Q K + + + + +K++++
Sbjct: 791 SKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERE 848
Score = 44.7 bits (104), Expect = 8e-05
Identities = 45/202 (22%), Positives = 85/202 (42%), Gaps = 18/202 (8%)
Query: 45 KKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRS 104
K+ + ++GS + ++ EE +N KK+ S S KK K++K+ S R+
Sbjct: 1105 KRNTKEIQSGSSS-SDAEESSEDNKKKKQRTS----------SKKKAVIVKEKKRNSLRT 1153
Query: 105 SSSSSSSD----SSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHES--ESESKESVK 158
S+ +D SSS D + +G ++K ++ S+H +S E++
Sbjct: 1154 STKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALS 1213
Query: 159 KK-KKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQ 217
K + D+ + + D + K+ LSS+ SD E + K+ + E
Sbjct: 1214 KSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENP 1273
Query: 218 AKEKVKKKKKKQHKKHSKKKKK 239
E+ K + + S++ KK
Sbjct: 1274 GDEEAKNQVNSESDSDSEESKK 1295
Score = 39.7 bits (91), Expect = 0.002
Identities = 50/238 (21%), Positives = 97/238 (40%), Gaps = 44/238 (18%)
Query: 53 TGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK----KRKKKSCRSSSSS 108
T K L + + + ++ K + + R+ SG++ +KK + K +KK+ +S SS+
Sbjct: 721 TNHKTLYDLKTQAGKDDKGK--RKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSN 778
Query: 109 SSSD---------------------SSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQ--SS 145
S+ ++ DS ++EK K + +++ K+SQ SS
Sbjct: 779 YDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSS 838
Query: 146 THESESESKESVKKKKKSKDETEKEKDVRS-LSKKRKKSYPDD--KPLSSESSSESDYE- 201
+ +E+ + + D+ ++R L KK++ S D LS + S + E
Sbjct: 839 DDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEV 898
Query: 202 -------EDVQAKKKRRCEEREQA----KEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
E + K + C++ + EK KK + KK+ K G+ K +
Sbjct: 899 RKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKK 956
Score = 38.9 bits (89), Expect = 0.004
Identities = 40/182 (21%), Positives = 77/182 (42%), Gaps = 14/182 (7%)
Query: 67 ENWKKELEKSREKLLSGNESSSKKRERKKKRK-KKSCRSSSSSSSSDSSSSSSDSEDEEK 125
EN E E L ES ++ R K ++ ++ +S+SD + + E ++
Sbjct: 594 ENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKL 653
Query: 126 KQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYP 185
R+K K+N S S ++ +K K+ ++ D+ ++ ++ K+ +
Sbjct: 654 SVPVRKKDKRN-----SSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSR--- 705
Query: 186 DDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSH 245
+S SSS++D E + K + + QA + K K+K++ K G S
Sbjct: 706 ----MSHSSSSDTDINE-IHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSA 760
Query: 246 KS 247
KS
Sbjct: 761 KS 762
Score = 37.7 bits (86), Expect = 0.009
Identities = 44/216 (20%), Positives = 95/216 (43%), Gaps = 23/216 (10%)
Query: 45 KKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRK------ 98
KK+ + + S +E E+++ K ++ +K + + + K +K
Sbjct: 767 KKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQG 826
Query: 99 KKSCRSSSSSSSSDSS--------SSSSDSEDEEK--KQGKRRKKKKNRSYKSSQSSTHE 148
K+ ++S SS D+ SS+ + D++ + + R KK ++ S+
Sbjct: 827 HKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKL 886
Query: 149 SESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDD---KPLSSESSSESDYEEDVQ 205
S E + + +K + EK K +++ + K+ + D K L + S E+ ED +
Sbjct: 887 SGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDET--SEDDK 944
Query: 206 AKKKRRCEEREQAKEKVKK--KKKKQHKKHSKKKKK 239
+ K+ EE+++ + KK K ++Q++ S +K
Sbjct: 945 KQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEK 980
Score = 36.2 bits (82), Expect = 0.027
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Query: 106 SSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKD 165
+S S S S SSD ++KK+GK+ KK + S S + + + S + + D
Sbjct: 1874 ASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVD 1933
Query: 166 ETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207
ET V SL + K+ P S D+ D A+
Sbjct: 1934 ETGNNPSV-SLKLEESKATSSSNPSSPAPDWYKDFVTDADAE 1974
Score = 32.0 bits (71), Expect = 0.51
Identities = 32/164 (19%), Positives = 73/164 (44%), Gaps = 16/164 (9%)
Query: 55 SKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRK-----KKSCRSSSSSS 109
+K L E MN ++ K L+++ + S S++K R+ K + KK+ +
Sbjct: 318 AKKLIETTANMNSSYVKFLKQATDN--SEISSATKLRQLKAFKSVLADIKKAHLALEEDL 375
Query: 110 SSDSSSSSSDSEDEEKKQGK---------RRKKKKNRSYKSSQSSTHESESESKESVKKK 160
+S+ + + ++++ K+ K RK +K + + S E++ K+ +
Sbjct: 376 NSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEH 435
Query: 161 KKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDV 204
TE+++ +S + KKS ++P +++ D + D+
Sbjct: 436 MHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDI 479
Score = 31.2 bits (69), Expect = 0.88
Identities = 40/188 (21%), Positives = 72/188 (38%), Gaps = 21/188 (11%)
Query: 80 LLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSY 139
L++ S + E+ ++ KK + S S+ +S S + +KK + S
Sbjct: 238 LVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSC 297
Query: 140 KSSQSSTHESESESKESVKKKKKSKDETEK--------------EKDVRSLSKKR----- 180
S + ++ + KE +KK KK + T ++ S +K R
Sbjct: 298 SGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAF 357
Query: 181 KKSYPDDKP--LSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKK 238
K D K L+ E S++ K++ +E + K + K +K K + +KK
Sbjct: 358 KSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKK 417
Query: 239 KKSGSSHK 246
S S K
Sbjct: 418 DISKSEAK 425
Score = 30.4 bits (67), Expect = 1.5
Identities = 26/93 (27%), Positives = 34/93 (36%), Gaps = 13/93 (13%)
Query: 118 SDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLS 177
S E EE R +N S S + SKE + +EK K S
Sbjct: 25 SSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKE------EGTSSSEKSKSSGSSR 78
Query: 178 KKRKKSY-------PDDKPLSSESSSESDYEED 203
KRK S D+KPL E+ +E E+
Sbjct: 79 SKRKPSIVTKYVESDDEKPLDDETVNEDASNEN 111
Score = 27.7 bits (60), Expect = 9.7
Identities = 27/123 (21%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
Query: 63 EKMNENWKKELEKSREKLL--SGNESSSKKRERKKKRKKKSCRSSSSSSSSD----SSSS 116
E M+E+ L + L S ES + + + + S S S+SD S
Sbjct: 4 EPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEE 63
Query: 117 SSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSL 176
+ S ++ K G R K+K S + E + + S + +E + ++SL
Sbjct: 64 GTSSSEKSKSSGSSRSKRKPSIVTKYVES--DDEKPLDDETVNEDASNENSENDITMQSL 121
Query: 177 SKK 179
K+
Sbjct: 122 PKE 124
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 69.3 bits (168), Expect = 3e-12
Identities = 65/225 (28%), Positives = 109/225 (48%), Gaps = 47/225 (20%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKL-LSGNESSSKKRER 93
N P EE K Q+ S++ ++ EE ++ L R KL +S ES +K+ +
Sbjct: 1307 NEENPGDEEAKNQVN-----SESDSDSEESKKPRYRHRL--LRHKLTVSDGESGEEKKTK 1359
Query: 94 KKKRKKKSCRSSSSSSSSDSSSSS----------SDSEDE-------------EKKQGKR 130
K+ K+ R+ SS DS S S+SEDE E+ Q
Sbjct: 1360 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY 1419
Query: 131 RKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEK--------DVRSLSKKRK- 181
++KKK R K + S+ E++S S+E ++K++ ++E E+E+ D +S K RK
Sbjct: 1420 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKK 1479
Query: 182 --KSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKK 224
K DDK L +E+ + EE+ +++R ERE+ +EK+++
Sbjct: 1480 IRKILKDDK-LRTETQNALKEEEE----RRKRIAEREREREKLRE 1519
Score = 67.0 bits (162), Expect = 1e-11
Identities = 55/207 (26%), Positives = 99/207 (47%), Gaps = 7/207 (3%)
Query: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC 102
++++Q E+ G++ L E EE + + K +++ + G + S K R+ K KKK
Sbjct: 1004 KMEQQYESSSDGTEKLPEREEICH--FPKGIKQIKNGTTDGEKKSKKIRD--KTSKKKDE 1059
Query: 103 RSSSSSSSSDSSSSSSDSEDEEKKQGK--RRKKKKNRSYKSSQSSTHESESESKESVKKK 160
S + S+ S SED++ K G R KK+ KSS+ S S++++ K+
Sbjct: 1060 LSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKE 1119
Query: 161 KKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKE 220
++ K + ++ S + K + S SSS SD EE + KK++ + K
Sbjct: 1120 DGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSS-SDAEESSEDNKKKKQRTSSKKKA 1178
Query: 221 KVKKKKKKQHKKHSKKKKKKSGSSHKS 247
+ K+KK+ + S K+K+ +S S
Sbjct: 1179 VIVKEKKRNSLRTSTKRKQADITSSSS 1205
Score = 65.1 bits (157), Expect = 5e-11
Identities = 54/205 (26%), Positives = 91/205 (44%), Gaps = 8/205 (3%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLS--GNESSSKKRERKKKRKK 99
EE+K L + + GS E K + E E+ + +ES S E KK R +
Sbjct: 1278 EEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYR 1337
Query: 100 KSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESE-----SESK 154
+ S S ++ +E K+ K R ++K S S S ES SES+
Sbjct: 1338 HRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESE 1397
Query: 155 ESVKKKKKSKDETEKEKDVRSLS-KKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCE 213
+ + + +S + E E++ RS KK+++ + SSE+ S S+ EE+ + +++ E
Sbjct: 1398 DEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEE 1457
Query: 214 EREQAKEKVKKKKKKQHKKHSKKKK 238
E E+ +E K K K +K
Sbjct: 1458 EEEEEEEDENDDSKSPGKGRKKIRK 1482
Score = 58.5 bits (140), Expect = 5e-09
Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 11/153 (7%)
Query: 98 KKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESV 157
KK ++ SSD SS D +E KK+ ++ ++ ++ ES+S+S+ES
Sbjct: 1273 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESK 1332
Query: 158 KKKKK----------SKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207
K + + S E+ +EK + K K + + +SSE S +SD++E ++
Sbjct: 1333 KPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGR-NRRKVSSEDSEDSDFQESGVSE 1391
Query: 208 KKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKK 240
+ E+ ++ + + KK + + + S K+KKK
Sbjct: 1392 EVSESEDEQRPRTRSAKKAELEENQRSYKQKKK 1424
Score = 55.5 bits (132), Expect = 4e-08
Identities = 54/182 (29%), Positives = 80/182 (43%), Gaps = 23/182 (12%)
Query: 46 KQLENKKTG----SKALAEFEEKMNENWKKELEKSREKLLSGNESSSKK-------RERK 94
KQ++N T SK + + K + EKS K S + S KK RE+K
Sbjct: 1033 KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK 1092
Query: 95 K-------KRKKKSCRSSSSS--SSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSS 145
+ RK++ C SS + S + +SSD + + +RR R+ K QS
Sbjct: 1093 RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSG 1152
Query: 146 THESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSE--SSSESDYEED 203
+ S++E KKKK + + K+K V KKR K ++ SSS SD E+D
Sbjct: 1153 SSSSDAEESSEDNKKKKQR-TSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDD 1211
Query: 204 VQ 205
Q
Sbjct: 1212 DQ 1213
Score = 46.2 bits (108), Expect = 3e-05
Identities = 48/210 (22%), Positives = 86/210 (40%), Gaps = 19/210 (9%)
Query: 49 ENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSS 108
+N KT + ++ E+ E +E S E + + + + R+R K+++ S +
Sbjct: 866 KNLKTSQEGSSDDAERKQE---RETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVD 922
Query: 109 SSSDSSSSSSDSE----DEEKKQGKRRKKKKNRSYKSSQSSTHE-------SESESKESV 157
S S + E E K++ K K K + + S E S+ S++
Sbjct: 923 KLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDK 982
Query: 158 KKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQ 217
K+ KK +E +K D + K ++ Y SS +E E + + ++ +
Sbjct: 983 KQSKKGTEEKKKPSDFKKKVIKMEQQYE-----SSSDGTEKLPEREEICHFPKGIKQIKN 1037
Query: 218 AKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247
+KK KK K SKKK + S + KS
Sbjct: 1038 GTTDGEKKSKKIRDKTSKKKDELSDYAEKS 1067
Score = 46.2 bits (108), Expect = 3e-05
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 18/199 (9%)
Query: 43 EVKKQLENKKTG----SKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRK 98
EV+K E K+ +K + ++ +++ +K L+K + S ++ K+ ++K+K
Sbjct: 935 EVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKK 994
Query: 99 KKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVK 158
+ SSS +E +++ K K ++ T + E K
Sbjct: 995 PSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPK---GIKQIKNGTTDGE-------K 1044
Query: 159 KKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQA 218
K KK +D+T K+KD LS +KS K S +SS + + ++K+RC+ ++
Sbjct: 1045 KSKKIRDKTSKKKD--ELSDYAEKS--TGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKS 1100
Query: 219 KEKVKKKKKKQHKKHSKKK 237
K + +K+S K+
Sbjct: 1101 SRKRQDCSSSDTEKYSMKE 1119
Score = 44.7 bits (104), Expect = 8e-05
Identities = 53/238 (22%), Positives = 94/238 (39%), Gaps = 44/238 (18%)
Query: 32 DYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKR 91
D PR +++ E S + E E + E K + ++ + ++S+
Sbjct: 652 DLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNP 711
Query: 92 ERKKKRKKKSCRSSSSSSSSD------------SSSSSSDSE------------DEEKKQ 127
+ K K K + +S SD S SSSSD++ D + +
Sbjct: 712 KPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQA 771
Query: 128 GK--RRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDET---------EKEKDVRSL 176
GK + K+K+ S S T + +S + KKK+ +T E EK+++S+
Sbjct: 772 GKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKR---QTQSESSNYDSELEKEIKSM 828
Query: 177 SK-----KRKKSYPDDKPL-SSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKK 228
SK KK P+ K SSE S D Q K + + + + +K++++
Sbjct: 829 SKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERE 886
Score = 44.7 bits (104), Expect = 8e-05
Identities = 45/202 (22%), Positives = 85/202 (42%), Gaps = 18/202 (8%)
Query: 45 KKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRS 104
K+ + ++GS + ++ EE +N KK+ S S KK K++K+ S R+
Sbjct: 1143 KRNTKEIQSGSSS-SDAEESSEDNKKKKQRTS----------SKKKAVIVKEKKRNSLRT 1191
Query: 105 SSSSSSSD----SSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHES--ESESKESVK 158
S+ +D SSS D + +G ++K ++ S+H +S E++
Sbjct: 1192 STKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALS 1251
Query: 159 KK-KKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQ 217
K + D+ + + D + K+ LSS+ SD E + K+ + E
Sbjct: 1252 KSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENP 1311
Query: 218 AKEKVKKKKKKQHKKHSKKKKK 239
E+ K + + S++ KK
Sbjct: 1312 GDEEAKNQVNSESDSDSEESKK 1333
Score = 39.7 bits (91), Expect = 0.002
Identities = 50/238 (21%), Positives = 97/238 (40%), Gaps = 44/238 (18%)
Query: 53 TGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK----KRKKKSCRSSSSS 108
T K L + + + ++ K + + R+ SG++ +KK + K +KK+ +S SS+
Sbjct: 759 TNHKTLYDLKTQAGKDDKGK--RKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSN 816
Query: 109 SSSD---------------------SSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQ--SS 145
S+ ++ DS ++EK K + +++ K+SQ SS
Sbjct: 817 YDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSS 876
Query: 146 THESESESKESVKKKKKSKDETEKEKDVRS-LSKKRKKSYPDD--KPLSSESSSESDYE- 201
+ +E+ + + D+ ++R L KK++ S D LS + S + E
Sbjct: 877 DDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEV 936
Query: 202 -------EDVQAKKKRRCEEREQA----KEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
E + K + C++ + EK KK + KK+ K G+ K +
Sbjct: 937 RKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKK 994
Score = 38.9 bits (89), Expect = 0.004
Identities = 40/182 (21%), Positives = 77/182 (42%), Gaps = 14/182 (7%)
Query: 67 ENWKKELEKSREKLLSGNESSSKKRERKKKRK-KKSCRSSSSSSSSDSSSSSSDSEDEEK 125
EN E E L ES ++ R K ++ ++ +S+SD + + E ++
Sbjct: 632 ENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKL 691
Query: 126 KQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYP 185
R+K K+N S S ++ +K K+ ++ D+ ++ ++ K+ +
Sbjct: 692 SVPVRKKDKRN-----SSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSR--- 743
Query: 186 DDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSH 245
+S SSS++D E + K + + QA + K K+K++ K G S
Sbjct: 744 ----MSHSSSSDTDINE-IHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSA 798
Query: 246 KS 247
KS
Sbjct: 799 KS 800
Score = 37.7 bits (86), Expect = 0.009
Identities = 44/216 (20%), Positives = 95/216 (43%), Gaps = 23/216 (10%)
Query: 45 KKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRK------ 98
KK+ + + S +E E+++ K ++ +K + + + K +K
Sbjct: 805 KKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQG 864
Query: 99 KKSCRSSSSSSSSDSS--------SSSSDSEDEEK--KQGKRRKKKKNRSYKSSQSSTHE 148
K+ ++S SS D+ SS+ + D++ + + R KK ++ S+
Sbjct: 865 HKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKL 924
Query: 149 SESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDD---KPLSSESSSESDYEEDVQ 205
S E + + +K + EK K +++ + K+ + D K L + S E+ ED +
Sbjct: 925 SGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDET--SEDDK 982
Query: 206 AKKKRRCEEREQAKEKVKK--KKKKQHKKHSKKKKK 239
+ K+ EE+++ + KK K ++Q++ S +K
Sbjct: 983 KQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEK 1018
Score = 36.2 bits (82), Expect = 0.027
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Query: 106 SSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKD 165
+S S S S SSD ++KK+GK+ KK + S S + + + S + + D
Sbjct: 1912 ASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVD 1971
Query: 166 ETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207
ET V SL + K+ P S D+ D A+
Sbjct: 1972 ETGNNPSV-SLKLEESKATSSSNPSSPAPDWYKDFVTDADAE 2012
Score = 32.0 bits (71), Expect = 0.51
Identities = 32/164 (19%), Positives = 73/164 (44%), Gaps = 16/164 (9%)
Query: 55 SKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRK-----KKSCRSSSSSS 109
+K L E MN ++ K L+++ + S S++K R+ K + KK+ +
Sbjct: 356 AKKLIETTANMNSSYVKFLKQATDN--SEISSATKLRQLKAFKSVLADIKKAHLALEEDL 413
Query: 110 SSDSSSSSSDSEDEEKKQGK---------RRKKKKNRSYKSSQSSTHESESESKESVKKK 160
+S+ + + ++++ K+ K RK +K + + S E++ K+ +
Sbjct: 414 NSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEH 473
Query: 161 KKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDV 204
TE+++ +S + KKS ++P +++ D + D+
Sbjct: 474 MHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDI 517
Score = 31.2 bits (69), Expect = 0.88
Identities = 40/188 (21%), Positives = 72/188 (38%), Gaps = 21/188 (11%)
Query: 80 LLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSY 139
L++ S + E+ ++ KK + S S+ +S S + +KK + S
Sbjct: 276 LVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSC 335
Query: 140 KSSQSSTHESESESKESVKKKKKSKDETEK--------------EKDVRSLSKKR----- 180
S + ++ + KE +KK KK + T ++ S +K R
Sbjct: 336 SGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAF 395
Query: 181 KKSYPDDKP--LSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKK 238
K D K L+ E S++ K++ +E + K + K +K K + +KK
Sbjct: 396 KSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKK 455
Query: 239 KKSGSSHK 246
S S K
Sbjct: 456 DISKSEAK 463
Score = 27.7 bits (60), Expect = 9.7
Identities = 27/118 (22%), Positives = 42/118 (35%), Gaps = 13/118 (11%)
Query: 86 SSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSS 145
S SK +K SS S + S + +++ +K G + K +S
Sbjct: 7 SESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTS 66
Query: 146 THESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEED 203
+ E S S K+K S E D D+KPL E+ +E E+
Sbjct: 67 SSEKSKSSGSSRSKRKPSIVTKYVESD-------------DEKPLDDETVNEDASNEN 111
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 69.3 bits (168), Expect = 3e-12
Identities = 50/173 (28%), Positives = 85/173 (49%), Gaps = 15/173 (8%)
Query: 72 ELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRR 131
E KS +L+ S+ K++++++++++ +SS+S S+ SSSS+ D+ + KR+
Sbjct: 85 EFWKSSPSILAVQRSAILKKQQQQQQQQQ--HQASSNSGSEEDSSSSEDSDDSSSEVKRK 142
Query: 132 KKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRK---------- 181
K K S S +S S+S+ +++K S DETE + + ++ K RK
Sbjct: 143 KHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNG 202
Query: 182 KSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHS 234
K K +SS E D EED K+ R QA V K+ ++ K S
Sbjct: 203 KKILGQKKRQIDSSEEDDDEEDYDNDKR---SSRRQATVNVSYKEDEEMKTDS 252
Score = 59.7 bits (143), Expect = 2e-09
Identities = 51/185 (27%), Positives = 75/185 (40%), Gaps = 21/185 (11%)
Query: 82 SGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKS 141
SG+ SSS + S S S S S S S SD+ E K Q K K +KS
Sbjct: 30 SGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKS 89
Query: 142 SQS-------------STHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDK 188
S S + + + + S + + ++ D S KRKK +D
Sbjct: 90 SPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDW 149
Query: 189 PLS-----SESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGS 243
+S S+S S+S+ EE+ ++K C+E E E K K ++ + SK K K
Sbjct: 150 QMSGSGSPSQSGSDSESEEE---REKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKIL 206
Query: 244 SHKSR 248
K R
Sbjct: 207 GQKKR 211
Score = 46.2 bits (108), Expect = 3e-05
Identities = 48/191 (25%), Positives = 83/191 (43%), Gaps = 14/191 (7%)
Query: 50 NKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRK-KKSCRSSSSS 108
+KK +K L + + + ++L K ++ LSG SS +++ R KK K KS +
Sbjct: 1294 DKKPQAKQLQTRADYLIKLLSRDLAK--KEALSGAGSSKRRKARAKKNKAMKSIKVKEEI 1351
Query: 109 SSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETE 168
S S S S++++ K + + + RS KSS S + S E V ++S
Sbjct: 1352 KSDSSPLPSEKSDEDDDKLSESKSDGRERSKKSSVSDAPVHITASGEPVPISEES----- 1406
Query: 169 KEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRC------EEREQAKEKV 222
+E D ++ S +++ P L E E Q + R+C E KE
Sbjct: 1407 EELDQKTFSICKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYT 1466
Query: 223 KKKKKKQHKKH 233
++ KQ +K+
Sbjct: 1467 NPEQIKQWRKN 1477
Score = 37.0 bits (84), Expect = 0.016
Identities = 43/191 (22%), Positives = 76/191 (39%), Gaps = 23/191 (12%)
Query: 72 ELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSS---------DSSSSSSDSED 122
E E+ REK S + + K K +K RS S + DSS D ED
Sbjct: 165 ESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEED 224
Query: 123 -EEKKQGKRRKKKKNRSYKSSQSSTHESESESK---ESVKKKKKSKDET-EKEKDVRSLS 177
+ K+ RR+ N SYK + +S+ + E V + ++ + ET E+ D R
Sbjct: 225 YDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGR 284
Query: 178 KKRKKSYPDDKPLSSESSSESDYEED---------VQAKKKRRCEEREQAKEKVKKKKKK 228
K + + ++ + +E++ ++ K + +E +K++ +
Sbjct: 285 KGATGATTTIYAVEADGDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVR 344
Query: 229 QHKKHSKKKKK 239
KK KKK
Sbjct: 345 GMKKLDNYKKK 355
Score = 33.9 bits (76), Expect = 0.14
Identities = 22/104 (21%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
Query: 63 EKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSS----S 118
E+ ++NW++ + + + + L E + E + ++C S + S+ S S
Sbjct: 1037 ERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYS 1096
Query: 119 DSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKK 162
S+ + +GKR KK+ ++ S++E + +K KK
Sbjct: 1097 GSDSDSISEGKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKK 1140
Score = 32.3 bits (72), Expect = 0.39
Identities = 46/225 (20%), Positives = 95/225 (42%), Gaps = 21/225 (9%)
Query: 40 TWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLS-GNESSSKKRERKKKRK 98
T+ K+++ K K L E+ ++E +++LE +R+ L+ G+ + +E +
Sbjct: 1413 TFSICKERMRPVKAALKQLDRPEKGLSE--REQLEHTRQCLIKIGDHITECLKEYTNPEQ 1470
Query: 99 KKSCRSSSSSSSSDSSSSSSDSEDEEKKQG-KRRKKKKNRSYKSSQSSTHESESESKESV 157
K R + S + + + K K+R++ + S ++S + H + E +
Sbjct: 1471 IKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQNSDQNSNLNPHVIRNPDVERL 1530
Query: 158 KKKKKSKDET--------------EKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEED 203
K+ D + + KD R KKS +P SS S+ + + D
Sbjct: 1531 KENTNHDDSSRDSYSSDRHLTQYHDHHKD-RHQGDSYKKSDSRKRPYSSFSNGKDHRDWD 1589
Query: 204 VQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKK-KKKSGSSHKS 247
+ R +RE+ + K+ + + H+ + + K +S S H+S
Sbjct: 1590 HYKQDSRYYSDREKHR-KLDDHRSRDHRSNLEGSLKDRSHSDHRS 1633
Score = 30.0 bits (66), Expect = 2.0
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 6/75 (8%)
Query: 175 SLSKKRKKSYPDDKPLSSESSSESDY-----EEDVQAKKKRRCEEREQAKEKVKKKKKKQ 229
SL+ K PD KP + + + +DY D+ AKK+ + K + KK K
Sbjct: 1283 SLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDL-AKKEALSGAGSSKRRKARAKKNKA 1341
Query: 230 HKKHSKKKKKKSGSS 244
K K++ KS SS
Sbjct: 1342 MKSIKVKEEIKSDSS 1356
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 68.9 bits (167), Expect = 4e-12
Identities = 42/216 (19%), Positives = 112/216 (51%), Gaps = 13/216 (6%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95
R R + +++ E ++ K E E + + +++ E++R+K ++ ++RER++
Sbjct: 137 RGRDRQTDGQRERERQRDAEK---ERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDE-------EKKQGKRRKKKKNRSYKSSQSSTHE 148
+R+K++ S ++E E ++++ ++RK ++ R ++ + E
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Query: 149 SESE-SKESVKKKKKSKDETEKEKD-VRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQA 206
E+E KE +++ + +D ++K+ R +KR++ D+ + + + E + +
Sbjct: 254 RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER 313
Query: 207 KKKRRCE-EREQAKEKVKKKKKKQHKKHSKKKKKKS 241
+KR E ERE+ +E+ ++ ++ + K+ +K+K+++
Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQT 349
Score = 67.0 bits (162), Expect = 1e-11
Identities = 36/219 (16%), Positives = 102/219 (46%), Gaps = 6/219 (2%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKEL------EKSREKLLSGNESSSK 89
R R T +K+ E +K + ++ EN ++ E+ RE+ +
Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226
Query: 90 KRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHES 149
+ +R++ R++K+ R + + +S D+E+++ + R + ++R K + T
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
Query: 150 ESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKK 209
E ++ ++ ++ + + R ++KR++ ++ + +E D E++ + K+K
Sbjct: 287 RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK 346
Query: 210 RRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
R+ E + + ++ ++Q ++ ++++++ S + R
Sbjct: 347 RQTEMDRERNRQTGREGRRQAERERERERERDRQSARER 385
Score = 66.2 bits (160), Expect = 2e-11
Identities = 39/215 (18%), Positives = 112/215 (52%), Gaps = 6/215 (2%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERK 94
+R R + +K+ E ++T + + E++ N ++E E RE + + +RER+
Sbjct: 92 DRHRERQRDREKERE-RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERE 150
Query: 95 KKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESK 154
++R + R + + + ++ E+++ ++ ++++ R + ++ T + SE
Sbjct: 151 RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQ-REKENKTEDRHSERG 209
Query: 155 ESVKKKKKSKDETEKEKDV-RSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCE 213
+++++++ ETE+++ R ++RK +K E +SE + E D K++ R
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERD---KERERER 266
Query: 214 EREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
+R++ +++ +K++++Q + +++ ++ + + R
Sbjct: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETERKR 301
Score = 65.1 bits (157), Expect = 5e-11
Identities = 39/231 (16%), Positives = 111/231 (48%), Gaps = 25/231 (10%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNE------------NWKKELEKSREKLLS 82
+R R T E +KQ E ++ + +E+ E +++ ++ R++
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Query: 83 GNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSS 142
+ + +KRER+++R+++ R+ + + E+ + K R++K+ R +
Sbjct: 293 RDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
Query: 143 QSSTHESESESKESVKKKK-----------KSKDETEKEKDVRSLSKKRKKSYPDDKPLS 191
+ ++ E + ++++ + ++E E+++D R K+R++ D+
Sbjct: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRD-RDRQKERERQTEKDRDGQ 411
Query: 192 SESSSESDYEEDVQAKKKR-RCEEREQAKEKVKKKKKKQHKKHSKKKKKKS 241
E+ + + E+D ++++ R R ERE+ K + + ++++ ++ +++K+ +
Sbjct: 412 RETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRST 462
Score = 63.5 bits (153), Expect = 2e-10
Identities = 41/225 (18%), Positives = 103/225 (45%), Gaps = 12/225 (5%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWK-KELEKSREKLLSGNESSSKKRERK 94
R T E K+Q + ++ + EK E + E E R+K + R+R+
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
Query: 95 KK-RKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESES 153
+K R++++ R + D + E+++ + R +K+ R + + + E+E
Sbjct: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER 335
Query: 154 KESVKKKKKSKDETEKEKD---------VRSLSKKRKKSYPDDKPLSSE-SSSESDYEED 203
++++K K +TE +++ R ++R++ D+ + E E D + D
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
Query: 204 VQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
Q +++R+ E+ + + +K+++++ + S++ +++ K +
Sbjct: 396 RQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQK 440
Score = 60.1 bits (144), Expect = 2e-09
Identities = 41/229 (17%), Positives = 107/229 (46%), Gaps = 15/229 (6%)
Query: 35 NRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKK--RE 92
+R R +E +++ E ++T + + E + ++ ++ ++ RE+ + ++ RE
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
Query: 93 RKKKRKKKSCRSSSSSSSSDSSSS-----SSDSEDEEKKQGKRRKKKKNRSYKSSQSSTH 147
R ++R+K+ R ++ +D + E ++Q K+++ ++ + Q T
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Query: 148 ESESESKESVKKKKKSKD-----ETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEE 202
+ + +E K +++ ++ E E + + R + R++ + +E ++D E
Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
Query: 203 DVQAKKKRRCE---EREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
D Q K +R E ERE+A E+ ++ K++ ++ + + + + R
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER 281
Score = 59.7 bits (143), Expect = 2e-09
Identities = 35/218 (16%), Positives = 108/218 (49%), Gaps = 11/218 (5%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101
E +++ ++T ++ + + + +++ E+ REK +S ++ ER K+R+++
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
Query: 102 CRSSSSSSSSDSSSSSSDSE-----DEEKKQGKRRKKKKNRSYKSSQSSTHESESESKES 156
R +D + + +++ ++R++++ R + ++ E E E +
Sbjct: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 157 VKKKKKSKDETEKEKDVR-----SLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRR 211
+++++++ + EKE++ + + ++R + + +E E + E D Q+ ++R
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
Query: 212 CEEREQAKEKVKKKKKKQHK-KHSKKKKKKSGSSHKSR 248
ER++ +++ K+++++ K + +++ +K K R
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424
Score = 57.8 bits (138), Expect = 9e-09
Identities = 42/230 (18%), Positives = 109/230 (47%), Gaps = 24/230 (10%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95
R R T E +Q E ++ K E+ E ++E E+ R++ G ++R+ +K
Sbjct: 105 RERQTDRERDRQREKERNRQK------ERERET-EREGERGRDRQTDGQRERERQRDAEK 157
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSED-EEKKQGKRRKKKKNRSYK--SSQSSTHESESE 152
+R++++ R + + ++ +E+++ +R+++K+N++ S + E E E
Sbjct: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE 217
Query: 153 SKESVKKKKKS--------KDETEKEKDV-RSLSKKRKKSYPDDKPLSSESSSESD---- 199
++ ++K+++ K E E+EK R + +R+ ++ + + D
Sbjct: 218 TETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQK 277
Query: 200 -YEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
E K++RR E + + K +++++++ ++ +K+++ + R
Sbjct: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER 327
Score = 48.1 bits (113), Expect = 7e-06
Identities = 35/163 (21%), Positives = 71/163 (43%), Gaps = 11/163 (6%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95
R R E ++Q E ++ K E E K + + E++R+ G + ++RER++
Sbjct: 319 RERERERERERQRETERDREK---ERERKRKRQTEMDRERNRQTGREGRRQAERERERER 375
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSE--DEEKKQGKRRKKKKNRSYKSSQSSTHESESES 153
+R ++S R + E E+ + G+R +K+ K +S
Sbjct: 376 ERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRE 435
Query: 154 KESVKKKKKSKDETEKEKDVRSLSKKRKKS--YPDDKPLSSES 194
+E K+K ++ + + R ++RK+S Y + P ++ S
Sbjct: 436 RE----KQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARS 474
Score = 47.0 bits (110), Expect = 2e-05
Identities = 26/163 (15%), Positives = 80/163 (49%), Gaps = 12/163 (7%)
Query: 97 RKKKSCRSSSSSSSSDSSSSSSDSEDEEK---KQGKRRKKKK-------NRSYKSSQSST 146
R++ + S + +D +D E+ K+ +RR++K+ + + +
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 147 HESESESKESVKKKKKSKD-ETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQ 205
H +E + ++K ++ +T++E+D R K+R + ++ E D + D Q
Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERD-RQREKERNRQKERERETEREGERGRDRQTDGQ 146
Query: 206 AKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248
+++R+ + ++ + + +++++Q +++ +K++++ + + R
Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 68.6 bits (166), Expect = 5e-12
Identities = 52/176 (29%), Positives = 80/176 (45%), Gaps = 25/176 (14%)
Query: 69 WKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQG 128
W L+K RE+ L S +RER + S + S + EDEE K
Sbjct: 114 WPSLLDKEREESLRQKRLS--ERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPK-- 169
Query: 129 KRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDK 188
K S +S+ + S SKE KK++K K SK++ K Y +D
Sbjct: 170 -----KSTTSASTSEEEKKKKSSRSKERSKKRRKKKS-----------SKRKHKKYSEDS 213
Query: 189 PLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSS 244
S+S ++S E++ KRR ++ ++ ++K K + KK KK SKK +K+S S
Sbjct: 214 DSDSDSETDSSDEDN-----KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDS 264
Score = 67.4 bits (163), Expect = 1e-11
Identities = 52/155 (33%), Positives = 77/155 (49%), Gaps = 25/155 (16%)
Query: 49 ENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRK---KKSCRSS 105
E KK+ + A EEK KK+ +S+E+ SKKR +KK K KK S
Sbjct: 167 EPKKSTTSASTSEEEK-----KKKSSRSKER--------SKKRRKKKSSKRKHKKYSEDS 213
Query: 106 SSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKS-- 163
S S S++ SS D++ KK K+ KKKK+RS K + + +S ES +S K+ +
Sbjct: 214 DSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEF 273
Query: 164 -----KDETEKEKDVRSLSKKRKKSY--PDDKPLS 191
KD T+ E+ + + K+ DDKPL+
Sbjct: 274 LENPWKDRTKAEEPSDLIGPEAPKTLTSQDDKPLN 308
Score = 62.8 bits (151), Expect = 3e-10
Identities = 40/119 (33%), Positives = 63/119 (52%), Gaps = 2/119 (1%)
Query: 99 KKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESK-ESV 157
KKS S+S+S SS E +K++ K+ K+K++ Y S +SE++S E
Sbjct: 169 KKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDN 228
Query: 158 KKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEERE 216
K++ K + EK+K RS K+K+S K SS+SSS+ EE ++ K R + E
Sbjct: 229 KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKE-SSDSSSKESQEEFLENPWKDRTKAEE 286
Score = 46.2 bits (108), Expect = 3e-05
Identities = 53/220 (24%), Positives = 90/220 (40%), Gaps = 51/220 (23%)
Query: 75 KSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKK 134
+S ++ SG+ + + K K + S S S S S D + G +
Sbjct: 8 RSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGS 67
Query: 135 KNRSYKS-SQSSTHESES-----------------------------------ESKESVK 158
+N+SY+S S+S + E S E +ES++
Sbjct: 68 RNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLR 127
Query: 159 KKKKSKDETEKE---KDVRSLSKKRKK-------SYPDDKPLSSESSSESDYEEDVQAKK 208
+K+ S+ E E +V LS K + D++P S +S+ + EE KK
Sbjct: 128 QKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEE----KK 183
Query: 209 KRRCEEREQAKEKVKKK-KKKQHKKHSKKKKKKSGSSHKS 247
K+ +E++K++ KKK K++HKK+S+ S S S
Sbjct: 184 KKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223
Score = 41.2 bits (95), Expect = 8e-04
Identities = 24/83 (28%), Positives = 39/83 (46%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101
+E K+ KK+ + ++ E + + E + S E + + KK ++KK R KK
Sbjct: 190 KERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKY 249
Query: 102 CRSSSSSSSSDSSSSSSDSEDEE 124
+ S S +SS SSS EE
Sbjct: 250 KKKRSKKSRKESSDSSSKESQEE 272
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 68.6 bits (166), Expect = 5e-12
Identities = 56/200 (28%), Positives = 93/200 (46%), Gaps = 22/200 (11%)
Query: 29 TIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSS 88
T+++ + R EE + KK K E EK E ++E E+ R + E
Sbjct: 226 TVEELKEKLRKRTEEPDRDERLKK--EKQEREEREKEREREREERERKRRR---EEEERE 280
Query: 89 KKRERKKKRKKKS-CRSSSSSSSSDSSSSSSD----SEDEEKKQGKRRKKKKNRS----- 138
K+R R ++R+K+S RS SS +SD S S S E+++ + R ++++RS
Sbjct: 281 KERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
Query: 139 --YKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSS 196
++S S+S ++S K + KS+D + K SK+++K DDK S +S S
Sbjct: 341 RKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK-----SKEKEKRGSDDKKSSVKSGS 395
Query: 197 ESDYEEDVQAKKKRRCEERE 216
ED + K + E
Sbjct: 396 REKQSEDTNTESKESDTKNE 415
Score = 55.1 bits (131), Expect = 6e-08
Identities = 45/189 (23%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Query: 28 PTIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESS 87
P + L + + EE +K+ E ++ + EE+ E + + R++ S + S
Sbjct: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
Query: 88 SK------KRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKS 141
S+ R R KR + R S S S S SE + + + + R++ K+R KS
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS 360
Query: 142 SQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDY- 200
+ H S+S +E +K K+ + +K S R+K D S ES ++++
Sbjct: 361 YK---HRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
Query: 201 --EEDVQAK 207
ED++++
Sbjct: 418 GTSEDIKSE 426
Score = 48.1 bits (113), Expect = 7e-06
Identities = 28/128 (21%), Positives = 64/128 (50%), Gaps = 9/128 (7%)
Query: 123 EEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKK 182
EE + +R KK+K + E E E + +++K+ ++E E+EK+ ++RK+
Sbjct: 239 EEPDRDERLKKEKQ------EREEREKEREREREERERKRRREEEEREKERARDRERRKR 292
Query: 183 SYPDDKPLSSESS---SESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
S + S S S S + +++++RR R++ + + + +++H+ S+ +++
Sbjct: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRR 352
Query: 240 KSGSSHKS 247
KS
Sbjct: 353 SKSRDRKS 360
Score = 47.8 bits (112), Expect = 9e-06
Identities = 42/175 (24%), Positives = 70/175 (40%), Gaps = 8/175 (4%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREK----LLSGNESSSKKR 91
R R E +K+ ++ K A E+ + + SR S + S+ R
Sbjct: 261 REREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSR 320
Query: 92 ERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESES 151
ER++ R + RS S S S S D + + + RK K+RS + +S+
Sbjct: 321 ERRRSRSRDRRRSRSHDRS--ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378
Query: 152 ESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQA 206
+ K KK S +EK + + K+S D K + +S + E D Q+
Sbjct: 379 KEKRGSDDKKSSVKSGSREKQSEDTNTESKES--DTKNEVNGTSEDIKSEGDTQS 431
Score = 38.1 bits (87), Expect = 0.007
Identities = 32/180 (17%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 71 KELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKR 130
++L++ RE LL S+ + ++K+ + + D+ S D ++ G
Sbjct: 163 EQLKEERE-LLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYA 221
Query: 131 RKKKKNRSYKSS-QSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKP 189
+ K K + T E + + + +K+++ + E E+E++ +KR++
Sbjct: 222 KIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR------- 274
Query: 190 LSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKK-KKKKQHKKHSKKKKKKSGSSHKSR 248
E E + D + +K+ R R ++ ++ + + HK+ +++++S S + R
Sbjct: 275 --EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR 332
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 68.6 bits (166), Expect = 5e-12
Identities = 56/200 (28%), Positives = 93/200 (46%), Gaps = 22/200 (11%)
Query: 29 TIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSS 88
T+++ + R EE + KK K E EK E ++E E+ R + E
Sbjct: 226 TVEELKEKLRKRTEEPDRDERLKK--EKQEREEREKEREREREERERKRRR---EEEERE 280
Query: 89 KKRERKKKRKKKS-CRSSSSSSSSDSSSSSSD----SEDEEKKQGKRRKKKKNRS----- 138
K+R R ++R+K+S RS SS +SD S S S E+++ + R ++++RS
Sbjct: 281 KERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
Query: 139 --YKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSS 196
++S S+S ++S K + KS+D + K SK+++K DDK S +S S
Sbjct: 341 RKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK-----SKEKEKRGSDDKKSSVKSGS 395
Query: 197 ESDYEEDVQAKKKRRCEERE 216
ED + K + E
Sbjct: 396 REKQSEDTNTESKESDTKNE 415
Score = 55.1 bits (131), Expect = 6e-08
Identities = 45/189 (23%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Query: 28 PTIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESS 87
P + L + + EE +K+ E ++ + EE+ E + + R++ S + S
Sbjct: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
Query: 88 SK------KRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKS 141
S+ R R KR + R S S S S SE + + + + R++ K+R KS
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS 360
Query: 142 SQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDY- 200
+ H S+S +E +K K+ + +K S R+K D S ES ++++
Sbjct: 361 YK---HRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVN 417
Query: 201 --EEDVQAK 207
ED++++
Sbjct: 418 GTSEDIKSE 426
Score = 48.1 bits (113), Expect = 7e-06
Identities = 28/128 (21%), Positives = 64/128 (50%), Gaps = 9/128 (7%)
Query: 123 EEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKK 182
EE + +R KK+K + E E E + +++K+ ++E E+EK+ ++RK+
Sbjct: 239 EEPDRDERLKKEKQ------EREEREKEREREREERERKRRREEEEREKERARDRERRKR 292
Query: 183 SYPDDKPLSSESS---SESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
S + S S S S + +++++RR R++ + + + +++H+ S+ +++
Sbjct: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRR 352
Query: 240 KSGSSHKS 247
KS
Sbjct: 353 SKSRDRKS 360
Score = 47.8 bits (112), Expect = 9e-06
Identities = 42/175 (24%), Positives = 70/175 (40%), Gaps = 8/175 (4%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREK----LLSGNESSSKKR 91
R R E +K+ ++ K A E+ + + SR S + S+ R
Sbjct: 261 REREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSR 320
Query: 92 ERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESES 151
ER++ R + RS S S S S D + + + RK K+RS + +S+
Sbjct: 321 ERRRSRSRDRRRSRSHDRS--ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKE 378
Query: 152 ESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQA 206
+ K KK S +EK + + K+S D K + +S + E D Q+
Sbjct: 379 KEKRGSDDKKSSVKSGSREKQSEDTNTESKES--DTKNEVNGTSEDIKSEGDTQS 431
Score = 38.1 bits (87), Expect = 0.007
Identities = 32/180 (17%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 71 KELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKR 130
++L++ RE LL S+ + ++K+ + + D+ S D ++ G
Sbjct: 163 EQLKEERE-LLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYA 221
Query: 131 RKKKKNRSYKSS-QSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKP 189
+ K K + T E + + + +K+++ + E E+E++ +KR++
Sbjct: 222 KIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR------- 274
Query: 190 LSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKK-KKKKQHKKHSKKKKKKSGSSHKSR 248
E E + D + +K+ R R ++ ++ + + HK+ +++++S S + R
Sbjct: 275 --EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR 332
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 68.2 bits (165), Expect = 6e-12
Identities = 63/224 (28%), Positives = 102/224 (45%), Gaps = 29/224 (12%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101
E KK+ + + + S++ + + + + +SR + S ++S S++R + +R++
Sbjct: 238 EPDKKEEKRRHSRSRSRSR-RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSH 296
Query: 102 CRSSSSSSSSDSSSSSSDSEDEEKKQGK---------------------RRKKKKNRSYK 140
R S S S + ED+EKK+ K RR + RS K
Sbjct: 297 SRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPK 356
Query: 141 SSQSSTHE-SESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESD 199
+S + S S S KK+KK + E+ +D R S +KK DK E SESD
Sbjct: 357 KPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKK-SKDKEKDRERKSESD 415
Query: 200 YEEDVQAKKKRRCEEREQA--KEKVKKKKKKQHKKHSKKKKKKS 241
+DV+ + R +E EQ EK KK++KK + S K K+ S
Sbjct: 416 --KDVK-QVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECS 456
Score = 59.3 bits (142), Expect = 3e-09
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 14/176 (7%)
Query: 55 SKALAEFEEKMNENWKKELEKSREKLLS-GNESSSKKRERKKKRKKKSCRSSSSSSSSDS 113
S++ ++ +K E+ +K+ K+ K S S S RER+++R + RS S
Sbjct: 304 SRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKR 363
Query: 114 SSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST------------HESESESKESVKKKK 161
S S S KK+ K++ K K RS + ST E +SES + VK+
Sbjct: 364 KLSRSPSPRRHKKE-KKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVT 422
Query: 162 KSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQ 217
+ DE E+ D K+ KK P + E S E + ++ K + E+
Sbjct: 423 RDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEE 478
Score = 57.4 bits (137), Expect = 1e-08
Identities = 43/192 (22%), Positives = 83/192 (43%), Gaps = 14/192 (7%)
Query: 71 KELEKSREKLLSGNESSSK-----KRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEK 125
KE+E++ +++ S K+E K++ + RS + S S S S +
Sbjct: 217 KEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRR 276
Query: 126 KQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDV---RSLSKKRKK 182
K R +++++S + +S + E S+ + K + K K++ EK++ +S S R+
Sbjct: 277 SHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRS 336
Query: 183 SYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKK------QHKKHSKK 236
+ S S + + ++ K++ + K +KKK K ++ S
Sbjct: 337 RSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTS 396
Query: 237 KKKKSGSSHKSR 248
KKKKS K R
Sbjct: 397 KKKKSKDKEKDR 408
Score = 48.9 bits (115), Expect = 4e-06
Identities = 43/190 (22%), Positives = 80/190 (42%), Gaps = 27/190 (14%)
Query: 82 SGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKS 141
+G S S K + K +++ + + S S++ D ++E+++ + R + + R S
Sbjct: 203 AGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPS 262
Query: 142 SQS-----STHESESESKESVKKKKKS--------------KDETEKEKDVRSLSKKRKK 182
S S S SK +++ KS T K +D + K++K+
Sbjct: 263 SSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKR 322
Query: 183 SYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHS----KKKK 238
S K S+ S S E +++RR ++ +K + K+K + S KK+K
Sbjct: 323 SKTPPKSYSTARRSRSASRE----RRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEK 378
Query: 239 KKSGSSHKSR 248
KK +SR
Sbjct: 379 KKDKDKERSR 388
Score = 40.4 bits (93), Expect = 0.001
Identities = 30/138 (21%), Positives = 64/138 (46%), Gaps = 9/138 (6%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95
R R KK K+ S++ + K + K+ E+SR++ K ++++K
Sbjct: 347 RSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEK 406
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEEK-KQGKRRKKKKNRSYKSSQSSTHES--ESE 152
R++K S S D + D ++EE+ ++ KK++ + ++ T E E
Sbjct: 407 DRERK------SESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKG 460
Query: 153 SKESVKKKKKSKDETEKE 170
+ +S+++ K + D+ +E
Sbjct: 461 TGDSLRESKVNGDDHHEE 478
Score = 28.5 bits (62), Expect = 5.7
Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 9/89 (10%)
Query: 45 KKQLENKKTGSKALAEFEEKMNENWK--KELEKSREKLLSGNESSSKKRERKK------- 95
+++ +KK SK + E+ +E+ K K++ + ++ G +S +K+E KK
Sbjct: 391 RERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSP 450
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEE 124
K K+ S + S +S + D +E+
Sbjct: 451 KTKECSVEKGTGDSLRESKVNGDDHHEED 479
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 67.4 bits (163), Expect = 1e-11
Identities = 52/185 (28%), Positives = 85/185 (45%), Gaps = 8/185 (4%)
Query: 67 ENWKKELEKS----REKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSED 122
E+++++L K+ + + + SSS S SSSSSSSS SSSSSS S
Sbjct: 129 EDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 188
Query: 123 EEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKR-- 180
K K K K S+ S + + S K SK+ ++K K+ + L +++
Sbjct: 189 SSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIV 248
Query: 181 -KKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
K ++ + KP+S E +S+ + K+ +R + + KK+ KK S +
Sbjct: 249 PKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKR-KKSSSEALF 307
Query: 240 KSGSS 244
KS SS
Sbjct: 308 KSFSS 312
Score = 51.2 bits (121), Expect = 8e-07
Identities = 54/205 (26%), Positives = 86/205 (41%), Gaps = 55/205 (26%)
Query: 82 SGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEK-----KQGKRRKKKKN 136
S + SSS S SSSSSSSS SSSSSS S K K+ K + K +
Sbjct: 152 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDS 211
Query: 137 RSYKSS-------------QSSTHESESE--------SKESVKKKKKSKDETEKEKDVRS 175
R +KS+ +SS E++ K + K+ K E + + ++ +
Sbjct: 212 REHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLT 271
Query: 176 LSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCE--------------------ER 215
++ + K P +P S+S E++ AKK+++ ++
Sbjct: 272 ITSGQDKKAPSKRPPISDS-------EELSAKKRKKSSSEALFKSFSSAPPLILTCSADK 324
Query: 216 EQAKEK--VKKKKKKQHKKHSKKKK 238
+Q K+K VK K K + S+KKK
Sbjct: 325 KQIKDKSHVKMGKVKIESETSEKKK 349
Score = 45.8 bits (107), Expect = 3e-05
Identities = 48/195 (24%), Positives = 84/195 (43%), Gaps = 18/195 (9%)
Query: 45 KKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRS 104
KKQ+++K + E + +E K L + ++ N+S + ++ KS
Sbjct: 324 KKQIKDKSHVKMGKVKIESETSEKKKSTLPPF-DDIVDPNDS-----DVEENISSKSDSE 377
Query: 105 SSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSK 164
S +SS SSSSSS + + ++QG R K S +E ES+ E +
Sbjct: 378 QPSPASSSSSSSSSFTPSQTRQQGPLRS-----IMKDLHSDDNEEESDEVED------ND 426
Query: 165 DETEKEKDV-RSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVK 223
+++E E+ V R S+ R+ S D S S+S + E K + + K +K
Sbjct: 427 NDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIK 486
Query: 224 KKKKKQHKKHSKKKK 238
+ K + K+ + K
Sbjct: 487 QSKSDKQIKNGECDK 501
Score = 38.9 bits (89), Expect = 0.004
Identities = 44/178 (24%), Positives = 76/178 (42%), Gaps = 28/178 (15%)
Query: 56 KALAEFEEKMNENWKKEL----EKSREKLLSGNESSSKKRERKKKRKKKSC--------R 103
K + E +EK +++ ++ E SR+ S ESS K +E K +++K +
Sbjct: 198 KLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPK 257
Query: 104 SSSSSSSSDSS----SSSSD----------SEDEEKKQGKRRKKKKNRSYKSSQSSTHES 149
S DS+ +S D S+ EE KR+K +KS S+
Sbjct: 258 PMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLI 317
Query: 150 ESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207
+ S + + K KS + K K S+K+K + P + ++SD EE++ +K
Sbjct: 318 LTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDI--VDPNDSDVEENISSK 373
>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
Length = 334
Score = 67.4 bits (163), Expect = 1e-11
Identities = 53/174 (30%), Positives = 82/174 (47%), Gaps = 20/174 (11%)
Query: 83 GNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKS- 141
G SS + E + KRKKK R SSSSSSSDS + S +K+G R+ + K+RS+
Sbjct: 2 GRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYS-------RKKGGRKSRSKSRSWSRD 54
Query: 142 --------SQSSTHESESESKESVKKKK---KSKDETEKEKDVRSLSKKRKKSYPDDKPL 190
+ H S S S ++K+ +S+ + + RS SK R + L
Sbjct: 55 LQPRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRL 114
Query: 191 SSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSS 244
S S S S+ + + + R ER + ++K K++K+K K + K G S
Sbjct: 115 RSHSRS-SERSSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGES 167
Score = 50.4 bits (119), Expect = 1e-06
Identities = 48/215 (22%), Positives = 90/215 (41%), Gaps = 23/215 (10%)
Query: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95
R T EE + + + K + + + + KK KSR K S + + R
Sbjct: 4 RSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSR-DLQPRSHSY 62
Query: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNR-------------SYKSS 142
R+++ SSSSS S S S S K +R + K+R S S
Sbjct: 63 DRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSE 122
Query: 143 QSSTHESESESKESVKKKKKSKDETEKEKD---------VRSLSKKRKKSYPDDKPLSSE 193
+SS + S S++ ++K + K++ EKEKD ++ K+ + P + +
Sbjct: 123 RSSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGESGNIKAGLEHLPPAEQ 182
Query: 194 SSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKK 228
+ + + AK + +E+ +E+ K++K++
Sbjct: 183 AKARLQLVLEAAAKADEALKAKERNEEEAKRRKEE 217
Score = 49.7 bits (117), Expect = 2e-06
Identities = 50/184 (27%), Positives = 79/184 (42%), Gaps = 12/184 (6%)
Query: 64 KMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDE 123
+ + + ++E R+K SSS + + +KK R S S S S S S
Sbjct: 3 RRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSY 62
Query: 124 EKKQGKRRKKKKNRSYKSSQS-STHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKK 182
+++ +R + + SY S + S S K ++ +SK T RS S+ R +
Sbjct: 63 DRR--RRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTR-----RSRSRPRLR 115
Query: 183 SYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHK-KHSKKKKKKS 241
S+ SS + S D + +K R E+RE KEK K K K+ H K + K+
Sbjct: 116 SHSRSSERSSHRRTRS-RSRDRERRKGRDKEKRE--KEKDKGKDKELHNIKRGESGNIKA 172
Query: 242 GSSH 245
G H
Sbjct: 173 GLEH 176
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/133 (27%), Positives = 67/133 (50%), Gaps = 19/133 (14%)
Query: 120 SEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDET-EKEKDVRSLSK 178
S+ EE+ + KR+KK + RS S SS+ +S + S++ +K +SK + ++ RS S
Sbjct: 6 SDTEEESRSKRKKKHRRRS---SSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSY 62
Query: 179 KRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKE-KVKKKKKKQHKKHSKKK 237
R++ + SSS S Y +K+ R R + K +V++ + K + S+ +
Sbjct: 63 DRRRRH--------RSSSSSSYGS---RRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSR 111
Query: 238 ---KKKSGSSHKS 247
+ S SS +S
Sbjct: 112 PRLRSHSRSSERS 124
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/133 (27%), Positives = 67/133 (50%), Gaps = 18/133 (13%)
Query: 117 SSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSL 176
SSD+E+E + ++KKK+R +SS SS+ +S + S++ +K +SK RS
Sbjct: 5 SSDTEEESRS----KRKKKHRR-RSSSSSSSDSRTYSRKKGGRKSRSKS--------RSW 51
Query: 177 SKK-RKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKE-KVKKKKKKQHKKHS 234
S+ + +S+ D+ SSS S Y +K+ R R + K +V++ + K + S
Sbjct: 52 SRDLQPRSHSYDRRRRHRSSSSSSYG---SRRKRSRSRSRGRGKSYRVQRSRSKSRTRRS 108
Query: 235 KKKKKKSGSSHKS 247
+ + + S S
Sbjct: 109 RSRPRLRSHSRSS 121
>gi|27883882 P18SRP protein [Homo sapiens]
Length = 155
Score = 67.4 bits (163), Expect = 1e-11
Identities = 47/133 (35%), Positives = 71/133 (53%), Gaps = 33/133 (24%)
Query: 113 SSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKD 172
SS+SS DS++E ++ K + ++ R ++E KKK+KSK++ +
Sbjct: 45 SSTSSEDSDEENEELNKLQALQEKRI--------------NEEEEKKKEKSKEKIK---- 86
Query: 173 VRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKK-KQHK 231
L KKRK+SY S S EED +KK++ +++E+ KEK K KK K HK
Sbjct: 87 ---LKKKRKRSY-----------SSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHK 132
Query: 232 KHSKKKKKKSGSS 244
K KK+KK+ SS
Sbjct: 133 KEKKKRKKEKHSS 145
Score = 53.5 bits (127), Expect = 2e-07
Identities = 41/111 (36%), Positives = 57/111 (51%), Gaps = 23/111 (20%)
Query: 106 SSSSSSDSSSSSSD------------SEDEEKKQGKRR-----KKKKNRSYKSSQSSTHE 148
SS+SS DS + + +E+EEKK+ K + KKK+ RSY SS ST E
Sbjct: 45 SSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSS--STEE 102
Query: 149 SESESK----ESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESS 195
S+ K + +KKK+ K +++K K + KKRKK P SSE S
Sbjct: 103 DTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFS 153
Score = 50.8 bits (120), Expect = 1e-06
Identities = 36/126 (28%), Positives = 66/126 (52%), Gaps = 16/126 (12%)
Query: 55 SKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK-KRKKKSCRSSSSSSSSDS 113
S +E ++ NE K L+ +EK ++ E K++ ++K K KKK RS SSSS+ +
Sbjct: 45 SSTSSEDSDEENEELNK-LQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEE- 102
Query: 114 SSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDV 173
D+ ++K++ ++++KKK + KS + H+ E KKK+ K++ +
Sbjct: 103 -----DTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKE--------KKKRKKEKHSSTPNS 149
Query: 174 RSLSKK 179
S+K
Sbjct: 150 SEFSRK 155
Score = 49.7 bits (117), Expect = 2e-06
Identities = 36/122 (29%), Positives = 62/122 (50%), Gaps = 24/122 (19%)
Query: 49 ENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSS 108
E + +K A E+++NE +K+ EKS+EK+ + KKKRK+
Sbjct: 54 EENEELNKLQALQEKRINEEEEKKKEKSKEKI-----------KLKKKRKR--------- 93
Query: 109 SSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETE 168
S SSS+ D+ ++K++ ++++KKK + KS + H+ E K+ KK+K S
Sbjct: 94 -SYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKE---KKKRKKEKHSSTPNS 149
Query: 169 KE 170
E
Sbjct: 150 SE 151
Score = 39.7 bits (91), Expect = 0.002
Identities = 23/55 (41%), Positives = 36/55 (65%), Gaps = 1/55 (1%)
Query: 190 LSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSS 244
+SS SS +SD EE+ + K + +E+ +E+ KKK+K + K KKK+K+S SS
Sbjct: 44 VSSTSSEDSD-EENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSS 97
Score = 37.4 bits (85), Expect = 0.012
Identities = 20/70 (28%), Positives = 41/70 (58%)
Query: 45 KKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRS 104
K +L+ K+ S + + EE ++ K++ +K +K ++S K +K+K+K+K +
Sbjct: 84 KIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKH 143
Query: 105 SSSSSSSDSS 114
SS+ +SS+ S
Sbjct: 144 SSTPNSSEFS 153
Score = 33.5 bits (75), Expect = 0.18
Identities = 19/72 (26%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101
E++K + + K++ S + E E+ + +K +K ++K K +++KK++KK
Sbjct: 83 EKIKLKKKRKRSYSSSSTE-EDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKE 141
Query: 102 CRSSSSSSSSDS 113
SS+ +SS S
Sbjct: 142 KHSSTPNSSEFS 153
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 67.0 bits (162), Expect = 1e-11
Identities = 51/224 (22%), Positives = 105/224 (46%), Gaps = 25/224 (11%)
Query: 46 KQLENKKTGSKALAEFEEKM------NENWKKELEKSREKLLSGNES--SSKKRERKKKR 97
++LE+K + SK A+ + +M ++++ K +K++ K N+ S++ E K+
Sbjct: 114 EELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKK 173
Query: 98 KKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESV 157
K+ R +SS S D S S +KK K + S ++ + ++ +++
Sbjct: 174 IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKA 233
Query: 158 KKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDV------------- 204
+KK++ + + ++EK K++++ K S + S+ +EE+
Sbjct: 234 EKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIP 293
Query: 205 ----QAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSS 244
+A+ E+ + +K K KKKK+ +K K+K+KK G S
Sbjct: 294 ASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPS 337
Score = 66.2 bits (160), Expect = 2e-11
Identities = 55/206 (26%), Positives = 98/206 (47%), Gaps = 37/206 (17%)
Query: 46 KQLENKKTGSKALAEFEEKMNENWKKELEKSREK--LLSGNESSSKKRERKKKRKKKSCR 103
K + KK K E E K + K +L K +EK L +G + SK++E ++K ++++ +
Sbjct: 226 KTVAQKKAEKK---ERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVK 282
Query: 104 S----------SSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESES 153
S +S + +++ D+E ++KK+ K++KK E E
Sbjct: 283 SKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKK---------------GEKEE 327
Query: 154 KESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCE 213
KE KKK SK V+++ + K +++ E E+++AK+K E
Sbjct: 328 KEKEKKKGPSK------ATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEE-E 380
Query: 214 EREQAKEKVKKKKKKQHKKHSKKKKK 239
EQ K + KK+K+K+ K+ KK+ K
Sbjct: 381 RLEQEKRERKKQKEKERKERLKKEGK 406
Score = 64.3 bits (155), Expect = 9e-11
Identities = 63/238 (26%), Positives = 99/238 (41%), Gaps = 30/238 (12%)
Query: 39 PTWEEVKKQLENKKTG---SKALAEFEEKMNE--NWKKELEKSREKLLSGNESSSKKRER 93
P + KK+ E KK L E EE E K + E K NE +++
Sbjct: 37 PQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDK 96
Query: 94 KKKR---KKKSCRSSSSSSSSDSSSSS-------------SDSEDEEKKQGKRRKKKKNR 137
KKK KK+S + S D S S SD +D+ K K+ K K +
Sbjct: 97 KKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQK 156
Query: 138 SYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKP-LSSESSS 196
S K S + ++ K + + S E+ E D S+K +K +KP + ES +
Sbjct: 157 SNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGN 216
Query: 197 ESD--------YEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHK 246
E D + KK+R ++R++ K K++K K+K+ + KK + K S +
Sbjct: 217 EDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQR 274
Score = 57.0 bits (136), Expect = 1e-08
Identities = 44/181 (24%), Positives = 87/181 (48%), Gaps = 18/181 (9%)
Query: 79 KLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNR- 137
K ++ ++ K+RERKK+ ++K+ + S+ +E ++ + K++
Sbjct: 226 KTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKV 285
Query: 138 ---------SYKSSQSST---HESESESKESVKKKKK-SKDETEKEKDVRSLSKKRKKSY 184
S + +++ T ++E + K+ KKKKK K+E EKEK + SK K+
Sbjct: 286 TVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKK-KGPSKATVKAM 344
Query: 185 PDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKV---KKKKKKQHKKHSKKKKKKS 241
+ E EE+ + K+ E + + +E++ K+++KKQ +K K++ KK
Sbjct: 345 QEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKE 404
Query: 242 G 242
G
Sbjct: 405 G 405
Score = 56.6 bits (135), Expect = 2e-08
Identities = 52/213 (24%), Positives = 98/213 (46%), Gaps = 20/213 (9%)
Query: 24 QSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSG 83
Q V +D L + RP +E+ K++ ++ SK ++E EL + E + G
Sbjct: 429 QGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSE---------SMELCAAVEVMEQG 479
Query: 84 NESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRR-KKKKNRSYKSS 142
+K E + + + + D + +SD E E+ + K + K+N +
Sbjct: 480 ---VPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEE 536
Query: 143 QSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEE 202
+ E + ES+E +++ +S+ E+D + +K D KP S E SS+S+Y+
Sbjct: 537 EEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKP-SKEMSSDSEYDS 595
Query: 203 DVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSK 235
D K+ E+A +K K++ +K+ +HSK
Sbjct: 596 DDDRTKE------ERAYDKAKRRIEKRRLEHSK 622
Score = 47.0 bits (110), Expect = 2e-05
Identities = 45/184 (24%), Positives = 76/184 (41%), Gaps = 45/184 (24%)
Query: 95 KKRKKKSCRSSSSSSSSDS------SSSSSDSEDEEKKQGKRRKKKKNRSYKSSQ----- 143
KK+K KS S+ D+ + ++ ++ +K +GK++K+KK + +
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKEL 62
Query: 144 ---------------------SSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKK 182
+ +E E SK+ KK +K K ++ + D L K K
Sbjct: 63 EELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSK 122
Query: 183 SYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKK-----QHKKHSKKK 237
S KP E S SD ++D K+ AK K +K KK + + +SKK
Sbjct: 123 SKKTAKP-KVEMYSGSDDDDDFNKLPKK-------AKGKAQKSNKKWDGSEEDEDNSKKI 174
Query: 238 KKKS 241
K++S
Sbjct: 175 KERS 178
Score = 45.1 bits (105), Expect = 6e-05
Identities = 45/246 (18%), Positives = 107/246 (43%), Gaps = 49/246 (19%)
Query: 42 EEVKKQLENKKTGS----KALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKR 97
E+ +K+ E KK S KA+ E K+ E +++ + E++ E +K++E ++
Sbjct: 324 EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLE 383
Query: 98 KKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSS-----THESESE 152
++K R + ++ KK+GK K + + ++++ E
Sbjct: 384 QEKRER---------KKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVP 434
Query: 153 SKESVKKKKKSKDETEKEKDVRSLSKK---------------------RKKSYPDDKPLS 191
SK+S+ KK+ ++ +++K + L K ++++ P +P
Sbjct: 435 SKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEE 494
Query: 192 SESSSE----------SDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKS 241
E + + SD E + K E +E +E+ +++++++ + S++++++
Sbjct: 495 EEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEE 554
Query: 242 GSSHKS 247
G S S
Sbjct: 555 GESEGS 560
Score = 38.9 bits (89), Expect = 0.004
Identities = 36/179 (20%), Positives = 75/179 (41%), Gaps = 17/179 (9%)
Query: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC 102
E E+ G K + ++K E +KE EK + + ++ + + K+ +++
Sbjct: 300 ETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQK 359
Query: 103 RSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKK 162
R + E+E +Q KR +KK + E E KE +KK+ K
Sbjct: 360 REEEERIKRLEELEAKRKEEERLEQEKRERKK-------------QKEKERKERLKKEGK 406
Query: 163 SKDETEKEKDVRS-LSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKE 220
++++E R+ + K ++ + P + ED KK+++ ++ ++KE
Sbjct: 407 LLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYED---KKRKKIPQQLESKE 462
Score = 35.4 bits (80), Expect = 0.046
Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 4/106 (3%)
Query: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC 102
EVK+ E ++ E EE+ E+ ++E E+ + G+E K + K K
Sbjct: 526 EVKENPEEEEEEE----EEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDK 581
Query: 103 RSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHE 148
+ S SS S D EE+ K +++ + R + S++ E
Sbjct: 582 KPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTE 627
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.294 0.112 0.285
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,027,537
Number of Sequences: 37866
Number of extensions: 527327
Number of successful extensions: 39625
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1429
Number of HSP's successfully gapped in prelim test: 1355
Number of HSP's that attempted gapping in prelim test: 5997
Number of HSP's gapped (non-prelim): 14684
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.