Guide to the Human Genome
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Search of human proteins with 27502393

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27502393 nuclear factor of activated T-cells, cytosolic
component 1 isoform A [Homo sapiens]
         (716 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27502393 nuclear factor of activated T-cells, cytosolic compo...  1474   0.0  
gi|19923350 nuclear factor of activated T-cells, cytosolic compo...  1435   0.0  
gi|27502386 nuclear factor of activated T-cells, cytosolic compo...  1352   0.0  
gi|27502391 nuclear factor of activated T-cells, cytosolic compo...  1352   0.0  
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca...   558   e-159
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca...   558   e-159
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca...   558   e-159
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal...   558   e-159
gi|27886539 nuclear factor of activated T-cells, cytoplasmic, ca...   525   e-149
gi|27886541 nuclear factor of activated T-cells, cytoplasmic, ca...   525   e-149
gi|209862843 nuclear factor of activated T-cells, cytoplasmic, c...   525   e-149
gi|27502388 nuclear factor of activated T-cells, cytosolic compo...   453   e-127
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...   414   e-115
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...   414   e-115
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom...   220   4e-57
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo...   220   4e-57
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho...   220   4e-57
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom...   220   4e-57
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho...   218   1e-56
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    56   1e-07
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ...    55   3e-07
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ...    54   5e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   3e-06
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              47   5e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   1e-04
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            45   2e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    45   2e-04
gi|157502169 astacin-like metalloendopeptidase [Homo sapiens]          44   7e-04
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    43   0.001
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             41   0.003

>gi|27502393 nuclear factor of activated T-cells, cytosolic
           component 1 isoform A [Homo sapiens]
          Length = 716

 Score = 1474 bits (3817), Expect = 0.0
 Identities = 716/716 (100%), Positives = 716/716 (100%)

Query: 1   MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT 60
           MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
Sbjct: 1   MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT 60

Query: 61  AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI 120
           AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
Sbjct: 61  AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI 120

Query: 121 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR 180
           EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
Sbjct: 121 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR 180

Query: 181 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST 240
           SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
Sbjct: 181 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST 240

Query: 241 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW 300
           SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
Sbjct: 241 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW 300

Query: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360
           LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
Sbjct: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360

Query: 361 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP 420
           PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
Sbjct: 361 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP 420

Query: 421 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT 480
           SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
Sbjct: 421 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT 480

Query: 481 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR 540
           ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
Sbjct: 481 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR 540

Query: 541 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK 600
           NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
Sbjct: 541 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK 600

Query: 601 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI 660
           QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
Sbjct: 601 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI 660

Query: 661 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF 716
           PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF
Sbjct: 661 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFF 716


>gi|19923350 nuclear factor of activated T-cells, cytosolic
           component 1 isoform B [Homo sapiens]
          Length = 825

 Score = 1435 bits (3715), Expect = 0.0
 Identities = 697/697 (100%), Positives = 697/697 (100%)

Query: 1   MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT 60
           MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT
Sbjct: 1   MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPT 60

Query: 61  AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI 120
           AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI
Sbjct: 61  AHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRI 120

Query: 121 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR 180
           EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR
Sbjct: 121 EITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSR 180

Query: 181 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST 240
           SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST
Sbjct: 181 SCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST 240

Query: 241 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW 300
           SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW
Sbjct: 241 SPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSW 300

Query: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360
           LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP
Sbjct: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360

Query: 361 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP 420
           PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP
Sbjct: 361 PPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLP 420

Query: 421 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT 480
           SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT
Sbjct: 421 SHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGT 480

Query: 481 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR 540
           ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR
Sbjct: 481 ADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLR 540

Query: 541 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK 600
           NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK
Sbjct: 541 NSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEK 600

Query: 601 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI 660
           QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI
Sbjct: 601 QSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEI 660

Query: 661 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 697
           PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN
Sbjct: 661 PPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 697


>gi|27502386 nuclear factor of activated T-cells, cytosolic
           component 1 isoform C [Homo sapiens]
          Length = 930

 Score = 1352 bits (3499), Expect = 0.0
 Identities = 656/659 (99%), Positives = 657/659 (99%)

Query: 39  SAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 98
           +A  EHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA
Sbjct: 26  AAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 85

Query: 99  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 158
           GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS
Sbjct: 86  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 145

Query: 159 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 218
           LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE
Sbjct: 146 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 205

Query: 219 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 278
           EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS
Sbjct: 206 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 265

Query: 279 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 338
           PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT
Sbjct: 266 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 325

Query: 339 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 398
           TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK
Sbjct: 326 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 385

Query: 399 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 458
           PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH
Sbjct: 386 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 445

Query: 459 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 518
           PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE
Sbjct: 446 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 505

Query: 519 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 578
           IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL
Sbjct: 506 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 565

Query: 579 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 638
           QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH
Sbjct: 566 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 625

Query: 639 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 697
           VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN
Sbjct: 626 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 684


>gi|27502391 nuclear factor of activated T-cells, cytosolic
           component 1 isoform E [Homo sapiens]
          Length = 812

 Score = 1352 bits (3499), Expect = 0.0
 Identities = 656/659 (99%), Positives = 657/659 (99%)

Query: 39  SAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 98
           +A  EHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA
Sbjct: 26  AAAPEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPA 85

Query: 99  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 158
           GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS
Sbjct: 86  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLS 145

Query: 159 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 218
           LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE
Sbjct: 146 LPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPE 205

Query: 219 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 278
           EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS
Sbjct: 206 EGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYS 265

Query: 279 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 338
           PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT
Sbjct: 266 PHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKT 325

Query: 339 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 398
           TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK
Sbjct: 326 TLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAK 385

Query: 399 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 458
           PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH
Sbjct: 386 PKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGH 445

Query: 459 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 518
           PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE
Sbjct: 446 PIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE 505

Query: 519 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 578
           IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL
Sbjct: 506 IPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL 565

Query: 579 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 638
           QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH
Sbjct: 566 QVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHH 625

Query: 639 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 697
           VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN
Sbjct: 626 VWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 684


>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 1 [Homo sapiens]
          Length = 1075

 Score =  558 bits (1439), Expect = e-159
 Identities = 345/706 (48%), Positives = 435/706 (61%), Gaps = 59/706 (8%)

Query: 24  GETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHST-LPAPCHNLQTSTPGIIPP 82
           GE   PAP   G+ + A+ E    AS  +    P P+  +T L  P H L + +  + P 
Sbjct: 19  GEDGAPAPPPPGS-RPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPS 77

Query: 83  ADHPS--GYGAALDGGPAGYFLSSGHTRPDGAPA-LESPRIEITSCLGLYHNN-NQFFHD 138
               S   Y    +   + Y        P G P   E P I+ITS     H   +    D
Sbjct: 78  FQLQSHKNYEGTCEIPESKY-------SPLGGPKPFECPSIQITSISPNCHQELDAHEDD 130

Query: 139 VEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCL-SPASSLSSRSCNSEASSYESNYSYPY 197
           +++ D        PS   L LP   +YR+ S   SPASS+SSRS  S+ASS ES  S+ Y
Sbjct: 131 LQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCES-LSHIY 189

Query: 198 ----------------ASPQTSPWQSP--CVSPKTTDPEEGFPRGLGACTLLGSPRHSPS 239
                            SP TSP  SP  C   +T   + G    L       SPR SP 
Sbjct: 190 DDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSL-------SPRQSPC 242

Query: 240 TSPRASVTEESWLGAR-----SSRPASPCNKRKYSLNGRQPPY----SPHHSPTPSPHGS 290
            SPR+SVT+E+WL  R     SSRP SPC KR++S    +  Y    SPHHSP PSP  S
Sbjct: 243 HSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHS--SAEVCYAGSLSPHHSPVPSPGHS 300

Query: 291 PRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKV 350
           PR SVT+D+WL N + +  S +  A+         D    +P+K+RKT+ +Q   +  K+
Sbjct: 301 PRGSVTEDTWL-NASVHGGSGLGPAVFPFQYCVETD----IPLKTRKTSEDQAAILPGKL 355

Query: 351 EPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFC-DQYLAVPQHPYQWAKPKPLSPTSYMS 409
           E   +D GS  P  + + +D    Q+  K   C DQ+L+VP  P+ W+KPKP     + +
Sbjct: 356 ELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPS-PFTWSKPKPGHTPIFRT 414

Query: 410 PTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLEN 469
            +LP LDW LP+H G  EL+IEVQPK+HHRAHYETEGSRGAVKAS GGHP+V+L GY E 
Sbjct: 415 SSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNE- 473

Query: 470 EPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRA 529
           +P+ LQ+FIGTADDR LRPHAFYQVHRITGKTV+T S E I+++TKVLEIPLLPEN+M A
Sbjct: 474 KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSA 533

Query: 530 VIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQ 589
            IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVH+PQPSG+ LSLQ+AS P+ECSQ
Sbjct: 534 SIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQ 593

Query: 590 RSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRD 649
           RSAQELP +EK S +S  V GG +MV++G NFL +SK+IF+EK  DG   WE+E K  R+
Sbjct: 594 RSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIRE 653

Query: 650 LCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
            C+   +V+E+PP+ N  +T+ V V FY+CNGKRK+SQ QRFTY P
Sbjct: 654 KCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTP 699


>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 4 [Homo sapiens]
          Length = 1045

 Score =  558 bits (1439), Expect = e-159
 Identities = 345/706 (48%), Positives = 435/706 (61%), Gaps = 59/706 (8%)

Query: 24  GETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHST-LPAPCHNLQTSTPGIIPP 82
           GE   PAP   G+ + A+ E    AS  +    P P+  +T L  P H L + +  + P 
Sbjct: 19  GEDGAPAPPPPGS-RPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPS 77

Query: 83  ADHPS--GYGAALDGGPAGYFLSSGHTRPDGAPA-LESPRIEITSCLGLYHNN-NQFFHD 138
               S   Y    +   + Y        P G P   E P I+ITS     H   +    D
Sbjct: 78  FQLQSHKNYEGTCEIPESKY-------SPLGGPKPFECPSIQITSISPNCHQELDAHEDD 130

Query: 139 VEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCL-SPASSLSSRSCNSEASSYESNYSYPY 197
           +++ D        PS   L LP   +YR+ S   SPASS+SSRS  S+ASS ES  S+ Y
Sbjct: 131 LQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCES-LSHIY 189

Query: 198 ----------------ASPQTSPWQSP--CVSPKTTDPEEGFPRGLGACTLLGSPRHSPS 239
                            SP TSP  SP  C   +T   + G    L       SPR SP 
Sbjct: 190 DDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSL-------SPRQSPC 242

Query: 240 TSPRASVTEESWLGAR-----SSRPASPCNKRKYSLNGRQPPY----SPHHSPTPSPHGS 290
            SPR+SVT+E+WL  R     SSRP SPC KR++S    +  Y    SPHHSP PSP  S
Sbjct: 243 HSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHS--SAEVCYAGSLSPHHSPVPSPGHS 300

Query: 291 PRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKV 350
           PR SVT+D+WL N + +  S +  A+         D    +P+K+RKT+ +Q   +  K+
Sbjct: 301 PRGSVTEDTWL-NASVHGGSGLGPAVFPFQYCVETD----IPLKTRKTSEDQAAILPGKL 355

Query: 351 EPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFC-DQYLAVPQHPYQWAKPKPLSPTSYMS 409
           E   +D GS  P  + + +D    Q+  K   C DQ+L+VP  P+ W+KPKP     + +
Sbjct: 356 ELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPS-PFTWSKPKPGHTPIFRT 414

Query: 410 PTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLEN 469
            +LP LDW LP+H G  EL+IEVQPK+HHRAHYETEGSRGAVKAS GGHP+V+L GY E 
Sbjct: 415 SSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNE- 473

Query: 470 EPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRA 529
           +P+ LQ+FIGTADDR LRPHAFYQVHRITGKTV+T S E I+++TKVLEIPLLPEN+M A
Sbjct: 474 KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSA 533

Query: 530 VIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQ 589
            IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVH+PQPSG+ LSLQ+AS P+ECSQ
Sbjct: 534 SIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQ 593

Query: 590 RSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRD 649
           RSAQELP +EK S +S  V GG +MV++G NFL +SK+IF+EK  DG   WE+E K  R+
Sbjct: 594 RSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIRE 653

Query: 650 LCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
            C+   +V+E+PP+ N  +T+ V V FY+CNGKRK+SQ QRFTY P
Sbjct: 654 KCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTP 699


>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 3 [Homo sapiens]
          Length = 1065

 Score =  558 bits (1439), Expect = e-159
 Identities = 345/706 (48%), Positives = 435/706 (61%), Gaps = 59/706 (8%)

Query: 24  GETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHST-LPAPCHNLQTSTPGIIPP 82
           GE   PAP   G+ + A+ E    AS  +    P P+  +T L  P H L + +  + P 
Sbjct: 19  GEDGAPAPPPPGS-RPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPS 77

Query: 83  ADHPS--GYGAALDGGPAGYFLSSGHTRPDGAPA-LESPRIEITSCLGLYHNN-NQFFHD 138
               S   Y    +   + Y        P G P   E P I+ITS     H   +    D
Sbjct: 78  FQLQSHKNYEGTCEIPESKY-------SPLGGPKPFECPSIQITSISPNCHQELDAHEDD 130

Query: 139 VEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCL-SPASSLSSRSCNSEASSYESNYSYPY 197
           +++ D        PS   L LP   +YR+ S   SPASS+SSRS  S+ASS ES  S+ Y
Sbjct: 131 LQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCES-LSHIY 189

Query: 198 ----------------ASPQTSPWQSP--CVSPKTTDPEEGFPRGLGACTLLGSPRHSPS 239
                            SP TSP  SP  C   +T   + G    L       SPR SP 
Sbjct: 190 DDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSL-------SPRQSPC 242

Query: 240 TSPRASVTEESWLGAR-----SSRPASPCNKRKYSLNGRQPPY----SPHHSPTPSPHGS 290
            SPR+SVT+E+WL  R     SSRP SPC KR++S    +  Y    SPHHSP PSP  S
Sbjct: 243 HSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHS--SAEVCYAGSLSPHHSPVPSPGHS 300

Query: 291 PRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKV 350
           PR SVT+D+WL N + +  S +  A+         D    +P+K+RKT+ +Q   +  K+
Sbjct: 301 PRGSVTEDTWL-NASVHGGSGLGPAVFPFQYCVETD----IPLKTRKTSEDQAAILPGKL 355

Query: 351 EPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFC-DQYLAVPQHPYQWAKPKPLSPTSYMS 409
           E   +D GS  P  + + +D    Q+  K   C DQ+L+VP  P+ W+KPKP     + +
Sbjct: 356 ELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPS-PFTWSKPKPGHTPIFRT 414

Query: 410 PTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLEN 469
            +LP LDW LP+H G  EL+IEVQPK+HHRAHYETEGSRGAVKAS GGHP+V+L GY E 
Sbjct: 415 SSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNE- 473

Query: 470 EPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRA 529
           +P+ LQ+FIGTADDR LRPHAFYQVHRITGKTV+T S E I+++TKVLEIPLLPEN+M A
Sbjct: 474 KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSA 533

Query: 530 VIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQ 589
            IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVH+PQPSG+ LSLQ+AS P+ECSQ
Sbjct: 534 SIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQ 593

Query: 590 RSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRD 649
           RSAQELP +EK S +S  V GG +MV++G NFL +SK+IF+EK  DG   WE+E K  R+
Sbjct: 594 RSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIRE 653

Query: 650 LCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
            C+   +V+E+PP+ N  +T+ V V FY+CNGKRK+SQ QRFTY P
Sbjct: 654 KCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTP 699


>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 2 [Homo sapiens]
          Length = 1068

 Score =  558 bits (1439), Expect = e-159
 Identities = 345/706 (48%), Positives = 435/706 (61%), Gaps = 59/706 (8%)

Query: 24  GETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHST-LPAPCHNLQTSTPGIIPP 82
           GE   PAP   G+ + A+ E    AS  +    P P+  +T L  P H L + +  + P 
Sbjct: 19  GEDGAPAPPPPGS-RPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPS 77

Query: 83  ADHPS--GYGAALDGGPAGYFLSSGHTRPDGAPA-LESPRIEITSCLGLYHNN-NQFFHD 138
               S   Y    +   + Y        P G P   E P I+ITS     H   +    D
Sbjct: 78  FQLQSHKNYEGTCEIPESKY-------SPLGGPKPFECPSIQITSISPNCHQELDAHEDD 130

Query: 139 VEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCL-SPASSLSSRSCNSEASSYESNYSYPY 197
           +++ D        PS   L LP   +YR+ S   SPASS+SSRS  S+ASS ES  S+ Y
Sbjct: 131 LQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCES-LSHIY 189

Query: 198 ----------------ASPQTSPWQSP--CVSPKTTDPEEGFPRGLGACTLLGSPRHSPS 239
                            SP TSP  SP  C   +T   + G    L       SPR SP 
Sbjct: 190 DDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSL-------SPRQSPC 242

Query: 240 TSPRASVTEESWLGAR-----SSRPASPCNKRKYSLNGRQPPY----SPHHSPTPSPHGS 290
            SPR+SVT+E+WL  R     SSRP SPC KR++S    +  Y    SPHHSP PSP  S
Sbjct: 243 HSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHS--SAEVCYAGSLSPHHSPVPSPGHS 300

Query: 291 PRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKV 350
           PR SVT+D+WL N + +  S +  A+         D    +P+K+RKT+ +Q   +  K+
Sbjct: 301 PRGSVTEDTWL-NASVHGGSGLGPAVFPFQYCVETD----IPLKTRKTSEDQAAILPGKL 355

Query: 351 EPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFC-DQYLAVPQHPYQWAKPKPLSPTSYMS 409
           E   +D GS  P  + + +D    Q+  K   C DQ+L+VP  P+ W+KPKP     + +
Sbjct: 356 ELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPS-PFTWSKPKPGHTPIFRT 414

Query: 410 PTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLEN 469
            +LP LDW LP+H G  EL+IEVQPK+HHRAHYETEGSRGAVKAS GGHP+V+L GY E 
Sbjct: 415 SSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNE- 473

Query: 470 EPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRA 529
           +P+ LQ+FIGTADDR LRPHAFYQVHRITGKTV+T S E I+++TKVLEIPLLPEN+M A
Sbjct: 474 KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSA 533

Query: 530 VIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQ 589
            IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVH+PQPSG+ LSLQ+AS P+ECSQ
Sbjct: 534 SIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQ 593

Query: 590 RSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRD 649
           RSAQELP +EK S +S  V GG +MV++G NFL +SK+IF+EK  DG   WE+E K  R+
Sbjct: 594 RSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIRE 653

Query: 650 LCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
            C+   +V+E+PP+ N  +T+ V V FY+CNGKRK+SQ QRFTY P
Sbjct: 654 KCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTP 699


>gi|27886539 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 2 isoform B [Homo sapiens]
          Length = 921

 Score =  525 bits (1352), Expect = e-149
 Identities = 330/707 (46%), Positives = 411/707 (58%), Gaps = 85/707 (12%)

Query: 29  PAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPC----------HNLQTSTPG 78
           P    GG+ +   +    +    ++P    P AH     P           + L+  +P 
Sbjct: 16  PGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPL 75

Query: 79  IIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHD 138
                + P  +G     GP   FLS+   +P GA  L SPRIEIT      H   Q    
Sbjct: 76  ASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQAVGP 127

Query: 139 VEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYES 191
           + + D     ++ P          TL +P  E YR+P CLSPASS SS S          
Sbjct: 128 LRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS---------- 177

Query: 192 NYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESW 251
                + S   SP+ SPCVSP    P++  P+         SPR SP  SPR S+ E+S 
Sbjct: 178 -----FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAEDSC 231

Query: 252 LGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD-SW 300
           LG  S      SR +SP  KR++S    L    P  SP  S +PSP  S  V+  D  S 
Sbjct: 232 LGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSP 291

Query: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360
            G      S+ I+ A+N+L TDS      G+P K  KT+ +  P            + + 
Sbjct: 292 AGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------VSAA 335

Query: 361 PPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----TSYM 408
           P  A      Y + + +       R+    +  L VP     W  PKPL P     +  +
Sbjct: 336 PSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICSIPV 390

Query: 409 SPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLE 468
           + +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA  GGHP+VQLHGY+E
Sbjct: 391 TASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYME 450

Query: 469 NEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMR 528
           N+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N+MR
Sbjct: 451 NKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMR 510

Query: 529 AVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECS 588
           A IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPIECS
Sbjct: 511 ATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECS 570

Query: 589 QRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDR 648
           QRSA ELP+VE+Q TDS  V GG++M+L+G NF  +SKV+F EK  DG  +WEMEA  D+
Sbjct: 571 QRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDK 630

Query: 649 DLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
           D  +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P
Sbjct: 631 DKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP 677


>gi|27886541 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 2 isoform C [Homo sapiens]
          Length = 925

 Score =  525 bits (1352), Expect = e-149
 Identities = 330/707 (46%), Positives = 411/707 (58%), Gaps = 85/707 (12%)

Query: 29  PAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPC----------HNLQTSTPG 78
           P    GG+ +   +    +    ++P    P AH     P           + L+  +P 
Sbjct: 16  PGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPL 75

Query: 79  IIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHD 138
                + P  +G     GP   FLS+   +P GA  L SPRIEIT      H   Q    
Sbjct: 76  ASLSGEPPGRFGEPDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQAVGP 127

Query: 139 VEVEDVLPSSKRSPSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYES 191
           + + D     ++ P          TL +P  E YR+P CLSPASS SS S          
Sbjct: 128 LRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS---------- 177

Query: 192 NYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESW 251
                + S   SP+ SPCVSP    P++  P+         SPR SP  SPR S+ E+S 
Sbjct: 178 -----FISDTFSPYTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAEDSC 231

Query: 252 LGARS------SRPASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD-SW 300
           LG  S      SR +SP  KR++S    L    P  SP  S +PSP  S  V+  D  S 
Sbjct: 232 LGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSP 291

Query: 301 LGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSP 360
            G      S+ I+ A+N+L TDS      G+P K  KT+ +  P            + + 
Sbjct: 292 AGYPPVAGSAVIMDALNSLATDSPC----GIPPKMWKTSPDPSP------------VSAA 335

Query: 361 PPPADFAPEDYSSFQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----TSYM 408
           P  A      Y + + +       R+    +  L VP     W  PKPL P     +  +
Sbjct: 336 PSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICSIPV 390

Query: 409 SPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLE 468
           + +LP L+W L S SG YELRIEVQPK HHRAHYETEGSRGAVKA  GGHP+VQLHGY+E
Sbjct: 391 TASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYME 450

Query: 469 NEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMR 528
           N+PL LQ+FIGTAD+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N+MR
Sbjct: 451 NKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMR 510

Query: 529 AVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECS 588
           A IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPIECS
Sbjct: 511 ATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECS 570

Query: 589 QRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDR 648
           QRSA ELP+VE+Q TDS  V GG++M+L+G NF  +SKV+F EK  DG  +WEMEA  D+
Sbjct: 571 QRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDK 630

Query: 649 DLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
           D  +PN L VEIP +RN+ I +PV V+FYV NGKRKRSQ Q FTY P
Sbjct: 631 DKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP 677


>gi|209862843 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 2 isoform D [Homo sapiens]
          Length = 901

 Score =  525 bits (1352), Expect = e-149
 Identities = 330/694 (47%), Positives = 408/694 (58%), Gaps = 82/694 (11%)

Query: 32  RAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGA 91
           R  G++   E   +  AS    PA P            + L+  +P      + P  +G 
Sbjct: 16  RIMGSVDQEEPNAHKVASPPSGPAYPDDVLD-------YGLKPYSPLASLSGEPPGRFGE 68

Query: 92  ALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRS 151
               GP   FLS+   +P GA  L SPRIEIT      H   Q    + + D     ++ 
Sbjct: 69  PDRVGPQK-FLSAA--KPAGASGL-SPRIEITPS----HELIQAVGPLRMRDAGLLVEQP 120

Query: 152 PSTA-------TLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSP 204
           P          TL +P  E YR+P CLSPASS SS S               + S   SP
Sbjct: 121 PLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSAS---------------FISDTFSP 165

Query: 205 WQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARS------SR 258
           + SPCVSP    P++  P+         SPR SP  SPR S+ E+S LG  S      SR
Sbjct: 166 YTSPCVSPNNGGPDDLCPQFQNIPAHY-SPRTSPIMSPRTSLAEDSCLGRHSPVPRPASR 224

Query: 259 PASPCNKRKYS----LNGRQPPYSPHHSPTPSPHGSPRVSVTDD-SWLGNTTQYTSSAIV 313
            +SP  KR++S    L    P  SP  S +PSP  S  V+  D  S  G      S+ I+
Sbjct: 225 SSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIM 284

Query: 314 AAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSS 373
            A+N+L TDS      G+P K  KT+ +  P            + + P  A      Y +
Sbjct: 285 DALNSLATDSPC----GIPPKMWKTSPDPSP------------VSAAPSKAGLPRHIYPA 328

Query: 374 FQHI-------RKGGFCDQYLAVPQHPYQWAKPKPLSP-----TSYMSPTLPALDWQLPS 421
            + +       R+    +  L VP     W  PKPL P     +  ++ +LP L+W L S
Sbjct: 329 VEFLGPCEQGERRNSAPESILLVPP---TW--PKPLVPAIPICSIPVTASLPPLEWPLSS 383

Query: 422 HSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTA 481
            SG YELRIEVQPK HHRAHYETEGSRGAVKA  GGHP+VQLHGY+EN+PL LQ+FIGTA
Sbjct: 384 QSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTA 443

Query: 482 DDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRN 541
           D+R+L+PHAFYQVHRITGKTV+TTS+E I+ NTKVLEIPL P+N+MRA IDCAGILKLRN
Sbjct: 444 DERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRN 503

Query: 542 SDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQ 601
           +DIELRKGETDIGRKNTRVRLVFRVH+P+ SGR +SLQ ASNPIECSQRSA ELP+VE+Q
Sbjct: 504 ADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQ 563

Query: 602 STDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIP 661
            TDS  V GG++M+L+G NF  +SKV+F EK  DG  +WEMEA  D+D  +PN L VEIP
Sbjct: 564 DTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIP 623

Query: 662 PFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
            +RN+ I +PV V+FYV NGKRKRSQ Q FTY P
Sbjct: 624 EYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHP 657


>gi|27502388 nuclear factor of activated T-cells, cytosolic
           component 1 isoform D [Homo sapiens]
          Length = 353

 Score =  453 bits (1166), Expect = e-127
 Identities = 225/225 (100%), Positives = 225/225 (100%)

Query: 473 MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID 532
           MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID
Sbjct: 1   MLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVID 60

Query: 533 CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA 592
           CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA
Sbjct: 61  CAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSA 120

Query: 593 QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK 652
           QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK
Sbjct: 121 QELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCK 180

Query: 653 PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 697
           PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN
Sbjct: 181 PNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPAN 225


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score =  414 bits (1064), Expect = e-115
 Identities = 292/696 (41%), Positives = 362/696 (52%), Gaps = 101/696 (14%)

Query: 41  EEEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAG 99
           E   YG A   +  P  P P  HS  P P  +         P         +   GGP G
Sbjct: 113 EPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGGPGG 163

Query: 100 YFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP------- 146
               +G     G   LE P I ITS            +N   + D    D  P       
Sbjct: 164 GAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGY 218

Query: 147 --------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYA 198
                    +  SPS  + SL S   + D S    A   +     SE +   S +     
Sbjct: 219 REAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGLG-- 275

Query: 199 SPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL------ 252
               SP  SP  SP+   PE+ +       +L G        SP     E+SWL      
Sbjct: 276 ----SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLSAPG 317

Query: 253 -GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWLGNT 304
               S RPASPC KR+YS +G     SP  S   S       P   P + +  D      
Sbjct: 318 PTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGP 377

Query: 305 TQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPA 364
             Y  +                  + +P K+R+T+ EQ  ++    EP   + G  P  A
Sbjct: 378 FDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGA 421

Query: 365 DFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPALDWQL 419
           +   E  +     RK      YLAVP  P  W+K +     P+  TS     LP LDW L
Sbjct: 422 E---ESVAPPGGSRKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPPLDWPL 473

Query: 420 PSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIG 479
           PS     ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL LQ+FIG
Sbjct: 474 PSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTLQMFIG 532

Query: 480 TADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKL 539
           TAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCAGILKL
Sbjct: 533 TADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKL 592

Query: 540 RNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVE 599
           RNSDIELRKGETDIGRKNTRVRLVFRVHVPQ  G+ +S+Q AS PIECSQRSAQELP VE
Sbjct: 593 RNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVE 652

Query: 600 KQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVE 659
             S  +  V GG+++VL+G NFL DSKV+F+E+ PDG   WE EA  +R      +L + 
Sbjct: 653 AYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLT 712

Query: 660 IPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
           +P + N+R++ PV V FYV NG+RKRS  Q F +LP
Sbjct: 713 VPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLP 748


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score =  414 bits (1064), Expect = e-115
 Identities = 292/696 (41%), Positives = 362/696 (52%), Gaps = 101/696 (14%)

Query: 41  EEEHYGYASSNVS-PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAG 99
           E   YG A   +  P  P P  HS  P P  +         P         +   GGP G
Sbjct: 50  EPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPS---------PGTWESQPARSVRLGGPGG 100

Query: 100 YFLSSGHTRPDGAPALESPRIEITSCL------GLYHNNNQFFHDVEVEDVLP------- 146
               +G     G   LE P I ITS            +N   + D    D  P       
Sbjct: 101 GAGGAG-----GGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGY 155

Query: 147 --------SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYA 198
                    +  SPS  + SL S   + D S    A   +     SE +   S +     
Sbjct: 156 REAGGQGGGAFFSPSPGSSSLSSWSFFSDASD-EAALYAACDEVESELNEAASRFGLG-- 212

Query: 199 SPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWL------ 252
               SP  SP  SP+   PE+ +       +L G        SP     E+SWL      
Sbjct: 213 ----SPLPSPRASPRPWTPEDPW-------SLYGP-------SPGGRGPEDSWLLLSAPG 254

Query: 253 -GARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPS-------PHGSPRVSVTDDSWLGNT 304
               S RPASPC KR+YS +G     SP  S   S       P   P + +  D      
Sbjct: 255 PTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGP 314

Query: 305 TQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPA 364
             Y  +                  + +P K+R+T+ EQ  ++    EP   + G  P  A
Sbjct: 315 FDYVGAPPA---------------ESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGA 358

Query: 365 DFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPK-----PLSPTSYMSPTLPALDWQL 419
           +   E  +     RK      YLAVP  P  W+K +     P+  TS     LP LDW L
Sbjct: 359 E---ESVAPPGGSRKEVAGMDYLAVPS-PLAWSKARIGGHSPIFRTS----ALPPLDWPL 410

Query: 420 PSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIG 479
           PS     ELRIEVQP++HHRAHYETEGSRGAVKA+ GGHP+V+L GY E +PL LQ+FIG
Sbjct: 411 PSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSE-KPLTLQMFIG 469

Query: 480 TADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKL 539
           TAD+R LRPHAFYQVHRITGK V+T S+EA++S TKVLE+ LLPEN+M A IDCAGILKL
Sbjct: 470 TADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKL 529

Query: 540 RNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVE 599
           RNSDIELRKGETDIGRKNTRVRLVFRVHVPQ  G+ +S+Q AS PIECSQRSAQELP VE
Sbjct: 530 RNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVE 589

Query: 600 KQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVE 659
             S  +  V GG+++VL+G NFL DSKV+F+E+ PDG   WE EA  +R      +L + 
Sbjct: 590 AYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLT 649

Query: 660 IPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
           +P + N+R++ PV V FYV NG+RKRS  Q F +LP
Sbjct: 650 VPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLP 685


>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
           sapiens]
          Length = 1455

 Score =  220 bits (560), Expect = 4e-57
 Identities = 129/299 (43%), Positives = 182/299 (60%), Gaps = 10/299 (3%)

Query: 413 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 471
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 191 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 248

Query: 472 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 531
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 249 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 306

Query: 532 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 591
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 307 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 366

Query: 592 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 651
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 367 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 423

Query: 652 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYL--PANGNAIFLTVSRE 708
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY   PA   A+ + V +E
Sbjct: 424 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKE 482


>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
           sapiens]
          Length = 1531

 Score =  220 bits (560), Expect = 4e-57
 Identities = 129/299 (43%), Positives = 182/299 (60%), Gaps = 10/299 (3%)

Query: 413 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 471
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 267 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 324

Query: 472 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 531
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 325 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 382

Query: 532 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 591
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 383 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 442

Query: 592 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 651
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 443 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 499

Query: 652 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYL--PANGNAIFLTVSRE 708
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY   PA   A+ + V +E
Sbjct: 500 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKE 558



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 47/205 (22%), Positives = 68/205 (33%), Gaps = 39/205 (19%)

Query: 47  YASSNVSPALP----LPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPA 98
           Y+  +V   LP    LP +  T  A          G  PPA    D  S   ++  GG  
Sbjct: 22  YSRESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGAC 81

Query: 99  GYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEV----------------- 141
             F +S           +S  +++ SC      +N+   + ++                 
Sbjct: 82  SSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTV 141

Query: 142 -------EDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYS 194
                  ED+L +S+ S       L S     + SC        S   N   SSY  N  
Sbjct: 142 LYISPPPEDLLDNSRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTE 196

Query: 195 YPYASPQTSPWQSPCVSPKTTDPEE 219
            P  S + +P Q P V  K  D EE
Sbjct: 197 VPRKSRKRNPKQRPGV--KRRDCEE 219


>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
           sapiens]
          Length = 1549

 Score =  220 bits (560), Expect = 4e-57
 Identities = 129/299 (43%), Positives = 182/299 (60%), Gaps = 10/299 (3%)

Query: 413 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 471
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 285 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 342

Query: 472 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 531
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 343 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 400

Query: 532 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 591
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 401 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 460

Query: 592 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 651
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 461 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 517

Query: 652 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYL--PANGNAIFLTVSRE 708
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY   PA   A+ + V +E
Sbjct: 518 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKE 576



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 44/192 (22%), Positives = 63/192 (32%), Gaps = 35/192 (18%)

Query: 56  LPLPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPAGYFLSSGHTRPDG 111
           L LP +  T  A          G  PPA    D  S   ++  GG    F +S       
Sbjct: 53  LQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYS 112

Query: 112 APALESPRIEITSCLGLYHNNNQFFHDVEV------------------------EDVLPS 147
               +S  +++ SC      +N+   + ++                        ED+L +
Sbjct: 113 TSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDN 172

Query: 148 SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 207
           S+ S       L S     + SC        S   N   SSY  N   P  S + +P Q 
Sbjct: 173 SRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQR 227

Query: 208 PCVSPKTTDPEE 219
           P V  K  D EE
Sbjct: 228 PGV--KRRDCEE 237


>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
           sapiens]
          Length = 1455

 Score =  220 bits (560), Expect = 4e-57
 Identities = 129/299 (43%), Positives = 182/299 (60%), Gaps = 10/299 (3%)

Query: 413 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 471
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 191 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 248

Query: 472 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 531
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 249 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 306

Query: 532 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 591
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 307 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 366

Query: 592 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 651
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 367 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 423

Query: 652 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYL--PANGNAIFLTVSRE 708
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY   PA   A+ + V +E
Sbjct: 424 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKE 482


>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
           sapiens]
          Length = 1548

 Score =  218 bits (556), Expect = 1e-56
 Identities = 125/284 (44%), Positives = 175/284 (61%), Gaps = 8/284 (2%)

Query: 413 PALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVK-ASAGGHPIVQLHGYLENEP 471
           P L  Q P  S   EL+I VQP++ HRA Y TEGSRG+VK  +  G P V+L G+  NEP
Sbjct: 285 PMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGH--NEP 342

Query: 472 LMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVI 531
           ++LQ+F+G    R+ +PH FYQ  R+TG+  +T   E  +  T V+E+ L P N+M   +
Sbjct: 343 VVLQVFVGNDSGRV-KPHGFYQACRVTGRN-TTPCKEVDIEGTTVIEVGLDPSNNMTLAV 400

Query: 532 DCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS 591
           DC GILKLRN+D+E R G     +K+TR RLVFRV++ +  G TL+LQ  S+PI C+Q +
Sbjct: 401 DCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPA 460

Query: 592 AQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLC 651
              +P + K+S  S  V G +++ L G NFL+ +KVIF E   D  + W+ EA+ D +L 
Sbjct: 461 G--VPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELF 517

Query: 652 KPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
             N L+V++PP+ +Q IT PV V  YV     +    Q FTY P
Sbjct: 518 HQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTP 561



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 44/192 (22%), Positives = 63/192 (32%), Gaps = 35/192 (18%)

Query: 56  LPLPTAHSTLPAPCHNLQTSTPGIIPPA----DHPSGYGAALDGGPAGYFLSSGHTRPDG 111
           L LP +  T  A          G  PPA    D  S   ++  GG    F +S       
Sbjct: 53  LQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYS 112

Query: 112 APALESPRIEITSCLGLYHNNNQFFHDVEV------------------------EDVLPS 147
               +S  +++ SC      +N+   + ++                        ED+L +
Sbjct: 113 TSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDN 172

Query: 148 SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 207
           S+ S       L S     + SC        S   N   SSY  N   P  S + +P Q 
Sbjct: 173 SRMSCQDEGCGLES-----EQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQR 227

Query: 208 PCVSPKTTDPEE 219
           P V  K  D EE
Sbjct: 228 PGV--KRRDCEE 237


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 130/535 (24%), Positives = 171/535 (31%), Gaps = 114/535 (21%)

Query: 7   PVPSKFPL----GPAAAVFGRGE--TLGPAPRA-------GGTMKSAEEEHYGYASSNVS 53
           P PS  P     GP  +V    E  T  P+P A       GG  + A       A+   S
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242

Query: 54  PALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAA-----LDGGPAGYFLSSG 105
           PA   P+A  T  AP H  Q    G   + PP   P    AA     L   P      S 
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302

Query: 106 HTRPDGAPALE-------SPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSP------ 152
              P   P+L+       +P  + T+ LG      Q  H       LPS   SP      
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLG--SPTLQATH-----SFLPSPPLSPLATPPP 355

Query: 153 -STATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQ----- 206
            +   L+LP L+A   P    P S L++ S  +  +        P++ P + P Q     
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415

Query: 207 --SPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCN 264
             SP VSP  T P +  P  L A  L   P  SP  SP  S +      A     A P  
Sbjct: 416 PASPPVSPSATPPSQA-PPSLAAPPLQVPP--SPPASPPMSPSATPPPQAPPPLAAPPLQ 472

Query: 265 KRKYSLNGRQPPYSPHHSPTPSPHG--SPRVSVTDDSWLGNTTQYTSSAIVAAINALTTD 322
             K       PP +P    TP      SP  S    +    +     S +          
Sbjct: 473 LAK------PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526

Query: 323 SSLDLGDGVPVKSRKTTLEQP--------------PSVALKVEPVGEDLGSPPPP----- 363
            +  L    P      TL+ P              P + L + P     G PPPP     
Sbjct: 527 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-----GPPPPPSRSPS 581

Query: 364 --------------ADFAPEDYSSFQHIRKGGFC-----DQYLAVPQHPYQWAKPKPLSP 404
                         A   PE+   +    +GG       D  LA   HP  W++  P  P
Sbjct: 582 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA-CHPAAWSR-GPAPP 639

Query: 405 TSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHP 459
            ++       L W   +  G  +    +         YETEG   A  A     P
Sbjct: 640 LAFRGAPGAPLPWPPATGPGSADGLCTI---------YETEGPESATPAPGALDP 685


>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 2 [Homo sapiens]
          Length = 548

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 73/289 (25%), Positives = 116/289 (40%), Gaps = 34/289 (11%)

Query: 423 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 476
           SGPY   IE   +   R  Y+ EG S G++           HP ++++GY     + + L
Sbjct: 17  SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76

Query: 477 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 530
                 D   RPH     H + GK      +EA L   + +       I  + +  +   
Sbjct: 77  ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129

Query: 531 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL-QVASNPI-ECS 588
           I    I    N   E ++G+ D+      VRL F+V V  PSGR L L  V S+PI +  
Sbjct: 130 IS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPIFDNR 184

Query: 589 QRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAK-TD 647
             +  EL +          + G +  +L      +D +V F          WE     + 
Sbjct: 185 APNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARGSFSQ 238

Query: 648 RDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLP 695
            D+ +  ++V   PP+ +  + +PV VS  +     R+ S+   F YLP
Sbjct: 239 ADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLP 287


>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 1 [Homo sapiens]
          Length = 551

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 73/293 (24%), Positives = 119/293 (40%), Gaps = 39/293 (13%)

Query: 423 SGPYELRIEVQPKSHHRAHYETEG-SRGAVKASAGG-----HPIVQLHGYLENEPLMLQL 476
           SGPY   IE   +   R  Y+ EG S G++           HP ++++GY     + + L
Sbjct: 17  SGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISL 76

Query: 477 FIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLE------IPLLPENSMRAV 530
                 D   RPH     H + GK      +EA L   + +       I  + +  +   
Sbjct: 77  ---VTKDPPHRPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQA 129

Query: 531 IDCAGILKLRNSD----IELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSL-QVASNPI 585
           I     ++  N+     IE ++G+ D+      VRL F+V V  PSGR L L  V S+PI
Sbjct: 130 ISQR--IQTNNNPFQVPIEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPPVLSHPI 183

Query: 586 -ECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEA 644
            +    +  EL +          + G +  +L      +D +V F          WE   
Sbjct: 184 FDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPG------WEARG 237

Query: 645 K-TDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCN-GKRKRSQYQRFTYLP 695
             +  D+ +  ++V   PP+ +  + +PV VS  +     R+ S+   F YLP
Sbjct: 238 SFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLP 290


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 86/312 (27%), Positives = 119/312 (38%), Gaps = 64/312 (20%)

Query: 7   PVPSKFPL----GPAAAVFGRGE--TLGPAPRA-------GGTMKSAEEEHYGYASSNVS 53
           P PS  P     GP  +V    E  T  P+P A       GG  + A       A+   S
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251

Query: 54  PALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAALDGGPAGYFLSSGHTRPD 110
           PA   P+A  T  AP H  Q    G   + PP   P    AA   GP     SS    P 
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS---SSPLATPS 308

Query: 111 GAPALES---PRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRD 167
            + AL+S   P +  T      H+++      ++   LP +  SPS      PSL+    
Sbjct: 309 PSAALQSQAPPTLPATP-----HSSSL---TCQLATPLPLAPPSPSAP----PSLQTLPS 356

Query: 168 PSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPR-GLG 226
           P    PA+  S  + +  + + ++ +S+           SP +SP  T P +  P   L 
Sbjct: 357 P----PATPPSQATTSLGSPTLQATHSF---------LPSPPLSPLATPPPQAPPALALP 403

Query: 227 ACTLLGSPRHSPSTSPRASVTEES-------WLGARSSRPASPCNKRKYSLNGRQPPYSP 279
                 SP  SP  SP A+ + ++        L A  S P SP           Q P+SP
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP---------PVQAPFSP 454

Query: 280 HHSPTPSPHGSP 291
             SP  SP  +P
Sbjct: 455 PASPPVSPSATP 466



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 61/276 (22%), Positives = 91/276 (32%), Gaps = 58/276 (21%)

Query: 9   PSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAP 68
           P+  PL P A          P+P+A     +A   H   A  +  P+ P+    S   +P
Sbjct: 412 PASPPLSPLAT---------PSPQA----PNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458

Query: 69  CHNLQTSTPGIIPPADHPSGYGA----ALDGGPAGYFLSSGHTRPDGAPA-LESPRIEIT 123
                  +P   PP+  P    A         PA   +S   T P  AP  L +P +++ 
Sbjct: 459 -----PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513

Query: 124 SCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSC-------LSPASS 176
                                 P  +  P+ AT   P L+A   P          SP++S
Sbjct: 514 K---------------------PPPQAPPALAT---PPLQALPSPPASFPGQAPFSPSAS 549

Query: 177 LSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVS----PKTTDPEEGFPRGLGACTLLG 232
           L      +         + P      SP  SP +     P T  P+           L  
Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 609

Query: 233 SPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKY 268
            P   PS SP ++++     G  SS  ++P   R Y
Sbjct: 610 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 47/172 (27%), Positives = 65/172 (37%), Gaps = 23/172 (13%)

Query: 130  HNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSY 189
            HN+  F+ +         + R PS  T   PS   +R PS  S  SSL  R  +    S+
Sbjct: 1539 HNHPSFYRE--------RTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSH 1590

Query: 190  ESNYSYPYASPQTSPWQSPCVSPKTTDPEEG----FPRGLGACTLLG------SPRHSPS 239
             S     ++SP    W+SP      + PE        RGL + +            HSPS
Sbjct: 1591 CSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPS 1650

Query: 240  TSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSP 291
                 S +E S   +   R  SP  +     + R P    H SP+   H SP
Sbjct: 1651 ERSHRSPSERSHRSSSERRHRSPSQR-----SHRGPSERSHCSPSERRHRSP 1697



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 38/144 (26%), Positives = 48/144 (33%), Gaps = 19/144 (13%)

Query: 148  SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 207
            S R PS  +   PS   +R PS  S       R  +    S+ S     + SP      S
Sbjct: 1677 SHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHS 1736

Query: 208  PCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRK 267
            P      +  E                 HSPS     S +E S       R  SP  +R 
Sbjct: 1737 PSERSHHSPSERR--------------HHSPSERSHCSPSERSHCSPSERRHRSPSERRH 1782

Query: 268  YSLNGRQPPYSPHHSPTPSPHGSP 291
            +S     P    HHSP+   H SP
Sbjct: 1783 HS-----PSEKSHHSPSERSHHSP 1801



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 39/148 (26%), Positives = 49/148 (33%), Gaps = 19/148 (12%)

Query: 148  SKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQS 207
            S RS S      PS  ++R PS  S  S    R  +    S+       + SP     +S
Sbjct: 1661 SHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRS 1720

Query: 208  PCVSPKTTDPEEGFPRGLGACTLLGSP----RHSPSTSPRASVTEESWLGARSSRPASPC 263
            P      +  E              SP     HSPS     S +E S          SP 
Sbjct: 1721 PARRSHRSPSERSHH----------SPSERSHHSPSERRHHSPSERSHCSPSERSHCSPS 1770

Query: 264  NKRKYSLNGRQPPYSPHHSPTPSPHGSP 291
             +R      R P    HHSP+   H SP
Sbjct: 1771 ERRH-----RSPSERRHHSPSEKSHHSP 1793


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 71/262 (27%), Positives = 91/262 (34%), Gaps = 66/262 (25%)

Query: 57  PLPTAH---STLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAP 113
           PL T H      PAPC      +P   PP + PS               S     P   P
Sbjct: 552 PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS---------------SIATPPPQAPP 596

Query: 114 ALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSP-------STATLSLPSLEAYR 166
           AL SP ++                       LPS   SP       +   L+LP L+A  
Sbjct: 597 ALASPPLQ----------------------GLPSPPLSPLATPPPQAPPXLALPPLQAPP 634

Query: 167 DPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQ-------SPCVSPKTTDPEE 219
            P    P S L++ S  +  +        P++ P + P Q       SP VSP  T P +
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 694

Query: 220 GFPRGLGACTLL--GSPRHSPSTSPRASVTEES-------WLGARSSRPASPCNKRKYSL 270
             P  L A  L    SP  SP  SP A+   ++        L    S PASP      + 
Sbjct: 695 A-PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753

Query: 271 NGRQPPY--SPHHSPTPSPHGS 290
             R PP   +P     PSP  S
Sbjct: 754 PPRVPPLLAAPPLQVPPSPPAS 775



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 118/448 (26%), Positives = 156/448 (34%), Gaps = 93/448 (20%)

Query: 7   PVPSKFPL----GPAAAVFGRGE--TLGPAPRA-------GGTMKSAEEEHYGYASSNVS 53
           P PS  P     GP  +V    E  T  P+P A       GG  + A       A+   S
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251

Query: 54  PALPLPTAHSTLPAPCHNLQTSTPG---IIPPADHPSGYGAALDGGPAGYFLSS---GHT 107
           PA   P+A  T  AP H  Q    G   + PP   P    AA   GP    LSS      
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP----LSSSPLATP 307

Query: 108 RPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRD 167
            P G  A   P                           P +  +P  AT  LP       
Sbjct: 308 SPSGTKARPVPP--------------------------PDNAATPLPAT--LPPSPPLAT 339

Query: 168 PSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSP---------CVSPKTTDPE 218
           P  L+P S  +  S  +  S   +  S    S  T P Q+P          V    T P 
Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS 399

Query: 219 EGFP------RGLGACTLLGSP----RHSPST-SPR---ASVTEESWLGARSSRPASPCN 264
              P        L A T LGSP     HS  T SPR   AS+T  S     S+ P SP  
Sbjct: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS--RPASTPPDSPPL 457

Query: 265 KRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAI--NALTTD 322
           +   SL    PP     SP  SP  SP +++     L +   ++  A ++++    L T 
Sbjct: 458 QAPLSLPA-SPPLQTSLSPAVSPLSSP-LTIHPLQALSSLASHSPQAPLSSLIMPPLETQ 515

Query: 323 SSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGF 382
           SSL             +L+ PP+ +L   P+       PPP   A    ++  H+     
Sbjct: 516 SSL----------APPSLQTPPA-SLTTPPLENLPSLAPPPLQTASAPLTT-PHLETPP- 562

Query: 383 CDQYLAVPQHPYQWAKPKPLSPTSYMSP 410
           C     +   P     P P +P+S  +P
Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATP 590



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 48/163 (29%), Positives = 65/163 (39%), Gaps = 25/163 (15%)

Query: 145 LPSSKRSP---STATLSLPSLEAYRDPS---CLSPASSLSSRSCNSEASSYESNYSYP-- 196
           LPS    P   ++A L+ P LE    P+     +P S L++    + +S        P  
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597

Query: 197 YASPQTSPWQSPCVSPKTTDPEEGFPR-GLGACTLLGSPRHSPSTSPRASVTEES----- 250
            ASP      SP +SP  T P +  P   L       SP  SP  SP A+ + ++     
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657

Query: 251 --WLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSP 291
              L A  S P SP           Q P+SP  SP  SP  +P
Sbjct: 658 VHLLQAPFSPPPSP---------PVQAPFSPPASPPVSPSATP 691



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 56/232 (24%), Positives = 76/232 (32%), Gaps = 45/232 (19%)

Query: 214 TTDPEEGFP------RGLGACTLLGSPRHSPSTSPR----------ASVTEESWLGARSS 257
           T+ P  G P      R   A T +G PR +PS  PR          +S +E S     ++
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS-----TT 218

Query: 258 RPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAIN 317
            P+    +R  +  G Q P S   S + +P  SP  S            + S      + 
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278

Query: 318 ALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHI 377
           AL            P K     L    S  L           P PP D A     +    
Sbjct: 279 ALRPPQVTP-----PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA---- 329

Query: 378 RKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSP----TLPALDWQLPSHSGP 425
                      +P  P   A P PL+P S  +P    TLP+     PS + P
Sbjct: 330 ----------TLPPSP-PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 54/185 (29%), Positives = 79/185 (42%), Gaps = 29/185 (15%)

Query: 151 SPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCV 210
           SPS +  S+PS     D    SP++S +S   NS  +S+ ++++   + P  S W SP  
Sbjct: 38  SPSASGASIPS-----DSGWASPSASGASTPSNSGWASFSASWA---SIPSDSGWASPSA 89

Query: 211 SPKTTDPEEGF--PRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKY 268
           S  +T  + G+  P   GA     S   SPS S  AS+    W        ASP      
Sbjct: 90  SWASTPSDSGWASPSASGASIPSDSGWASPSVS-GASIPSAFW--------ASP------ 134

Query: 269 SLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTS-SAIVAAINALTTDSSLDL 327
           S +G     +P  S   SP  S   + +D  W   +  +TS SA  A+ +A    +  D 
Sbjct: 135 SASGAS---TPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDS 191

Query: 328 GDGVP 332
           G   P
Sbjct: 192 GWASP 196



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 46/157 (29%), Positives = 65/157 (41%), Gaps = 10/157 (6%)

Query: 151 SPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYS-YPYASPQTSPWQSPC 209
           SPST+  S PS   +      S  +S SS SC S ++S  S  S   +ASP  S W S  
Sbjct: 202 SPSTSWASSPSDFGWASTPSDSGWAS-SSASCISPSASGASTSSDSGWASPSAS-WVSTS 259

Query: 210 VSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARS-SRPASPCNKRKY 268
            S  +T  + G+     +   + S       S   + +  SW  A S S  +SP   R  
Sbjct: 260 TSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRAS 319

Query: 269 SLN-GRQPPYSPHHSPTPS-----PHGSPRVSVTDDS 299
           +L+      +S   +  PS      H +  VS T DS
Sbjct: 320 TLSVSGWASFSASGASAPSDSGWTSHSASGVSTTSDS 356


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 95/385 (24%), Positives = 142/385 (36%), Gaps = 81/385 (21%)

Query: 2    PSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYG-----YASSNVSPAL 56
            P+ + P P   P  PA     +G    P+ + G T  +A   H G       S    PA+
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI 1395

Query: 57   PLPTAHSTLPA------------PCHNLQTSTPG---IIPPADHPSGYGAALDGGPAGYF 101
            P P    T PA            P      +TP    + PPA  P     +L   PA   
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTP----VSLKKAPA--- 1448

Query: 102  LSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPST-ATLSLP 160
                 + P G PA  S + + T       +  +     +V     S K++P+T A +  P
Sbjct: 1449 ----TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVA-TSSSPKKAPATPAPMGAP 1503

Query: 161  SLEAY---------------RDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPW 205
            +L A                RDP  ++P ++L S+   +  +  E+    P A    SP 
Sbjct: 1504 TLPAVIPSSPKEVPATPSSRRDP--IAPTATLLSKKTPATLAPKEA--LIPPAMTVPSPK 1559

Query: 206  QSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSR-----PA 260
            ++P +      P               +P    ++SP A VT  ++ GA S +     PA
Sbjct: 1560 KTPAIPTPKEAP--------------ATPSSKEASSPPA-VTPSTYKGAPSPKELLIPPA 1604

Query: 261  --SPCNKRKYSLNGRQPPYSPHHSP-TPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAIN 317
              SP  K   +     PP SP   P TP+P G+P       S L ++   TS A V    
Sbjct: 1605 VTSPSPKEAPTPPAVTPP-SPEKGPATPAPKGTPTSPPVTPSSLKDSP--TSPASVTCKM 1661

Query: 318  ALTTDSSLDLGDGVPVKSRKTTLEQ 342
              T   +     G+P K   T L++
Sbjct: 1662 GATVPQA---SKGLPAKKGPTALKE 1683



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 95/378 (25%), Positives = 124/378 (32%), Gaps = 68/378 (17%)

Query: 54   PALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAP 113
            PA P P       AP  ++ +S+P        P G  A+     A    ++    P G P
Sbjct: 900  PATPAPKQ-----APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP 954

Query: 114  ALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSP 173
            A  SP+   T                      PS K  P+T     PS +    P   +P
Sbjct: 955  ATPSPKWAPTPPAA----------------TPPSPKGGPAT-----PSPKGAPTPPAATP 993

Query: 174  ASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGA--CTLL 231
             S     +  S   +       P A    SP  SP  +P        FP+G         
Sbjct: 994  PSPKGGPATPSPKGA-----PTPPAVTPPSPKGSPAATP--------FPKGASTPPAATP 1040

Query: 232  GSPRHSPSTSPR---ASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSP-TPSP 287
             SP+ SP+ +P    A  T  + L +    PA+P  K   +     PP SP   P TPSP
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP-SPKGGPATPSP 1099

Query: 288  HGSPR-VSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSV 346
             G+P   + T  S  G               A        L    P  +  T    PPS 
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS- 1158

Query: 347  ALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTS 406
                 P G  L +PPP    AP   ++     KGG     LA P        PK    T 
Sbjct: 1159 -----PKG-GLATPPPKG--APTTPAATPPSPKGG-----LATP-------SPKGAPTTP 1198

Query: 407  YMSPTLPALDWQLPSHSG 424
              +P  P      PS  G
Sbjct: 1199 AATPPSPKGGLATPSPKG 1216



 Score = 38.1 bits (87), Expect = 0.029
 Identities = 114/473 (24%), Positives = 152/473 (32%), Gaps = 104/473 (21%)

Query: 7    PVPSKFPLGPAAAVFG-RGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTL 65
            P P   P  PAA     +G    P+P+   T  +A        S    PA P P    T 
Sbjct: 957  PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP-----SPKGGPATPSPKGAPTP 1011

Query: 66   PAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSC 125
            PA        +P   P     S   AA    P G    +    P GAP   +        
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS--PAATPLPKGAPTTPAA------- 1062

Query: 126  LGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSE 185
                               LPS K  P+T     PSL+    P   +P S     +  S 
Sbjct: 1063 ------------------TLPSPKGGPAT-----PSLKGAPTPPAATPPSPKGGPATPSP 1099

Query: 186  ASSYESNYSYPYASPQ----TSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPST- 240
              +     + P  SP+    T P +    +P  T P    P+G G  T    P+ +P+T 
Sbjct: 1100 KGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPPS---PKG-GLAT--PPPKGAPTTP 1152

Query: 241  -----SPRASVTEESWLGARSSRPASPCNKRK--YSLNGRQPPYSPHHSP--------TP 285
                 SP+  +      GA ++  A+P + +    + + +  P +P  +P        TP
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212

Query: 286  SPHGSPRV-SVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVP------------ 332
            SP G+P   + T  S  G     T S   A      T  S   G   P            
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLA--TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270

Query: 333  VKSRKTTLEQP-------PSVALKVEPVGEDLGSPP-----PPADFAPEDYSSFQHIRKG 380
              S K  L  P       P+V     P G    SPP     PPA   P    S       
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330

Query: 381  GFCDQYLAVPQHP---------YQWAKPKPLSPTSYMSPTLPALDWQLPSHSG 424
            G        P  P            +K  P +P+S   PT PA     PSH G
Sbjct: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA---ATPSHKG 1380



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 114/490 (23%), Positives = 164/490 (33%), Gaps = 105/490 (21%)

Query: 2    PSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTA 61
            P+TS   P   P  PAA       + G  P  G     A           V+P  P P  
Sbjct: 1301 PATS--PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA-----------VTP--PSPKG 1345

Query: 62   HSTLPA--PCHNLQTSTP----GIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPAL 115
              TLPA  P      +TP    G  PPA  PS       GGPA          P   PA+
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH-----KGGPA-----MTPPSPKRGPAI 1395

Query: 116  ESPRIEITSCLGLYHNNNQFFHDVEVEDVLP-SSKRSPSTATLSLPSLEAYRDPSCLSPA 174
             SP+ + TS                   V+P S K++P+T           R+ +     
Sbjct: 1396 PSPKGDPTS-----------------PAVIPLSPKKAPATPVT--------REGAATPSK 1430

Query: 175  SSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSP 234
              L+  +    +       S P   P T   +     P  T P    P          SP
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490

Query: 235  RHSPST-SPRASVTEESWLGARSSR-PASPCNKRK-----YSLNGRQPPYS--------P 279
            + +P+T +P  + T  + + +     PA+P ++R       +L  ++ P +        P
Sbjct: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550

Query: 280  HHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTT 339
                 PSP  +P +    ++        T S+  A+     T S+     G P       
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEA------PATPSSKEASSPPAVTPSTYK---GAPSPKE--- 1598

Query: 340  LEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPY---QW 396
            L  PP+V     P  ++  +PP     +PE         KG         P  P      
Sbjct: 1599 LLIPPAVT---SPSPKEAPTPPAVTPPSPE---------KGPATPAPKGTPTSPPVTPSS 1646

Query: 397  AKPKPLSPTSY---MSPTLPALDWQLPSHSGPYELR---IEVQPKSHHRAHYETEGSRGA 450
             K  P SP S    M  T+P     LP+  GP  L+   +   P+S       T      
Sbjct: 1647 LKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT 1706

Query: 451  VKASAGGHPI 460
             K+SA   PI
Sbjct: 1707 KKSSATSPPI 1716



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 70/297 (23%), Positives = 98/297 (32%), Gaps = 57/297 (19%)

Query: 140 EVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYS----Y 195
           E+   +PS    P+        ++     S L+P +S S + C +E S   +  S     
Sbjct: 729 EIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS-SPKECPTEDSGASATASSKGTL 787

Query: 196 PYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR 255
            Y +   SP     VSP+T  P                P    S  P   +         
Sbjct: 788 TYLADSPSPL-GVSVSPQTKRP----------------PTKKGSAGPDTPI-------GN 823

Query: 256 SSRPASPCN-----KRKYSLNGRQPPYSPHHSPTP-SPHGSPRVS-VTDDSWLGNTTQYT 308
            S P SP       +   S  G +   +  HSPTP SP G+P  S VT  S  G T    
Sbjct: 824 LSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPK 883

Query: 309 SSAIVAAIN-----------ALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDL 357
            +   + +N           A     +L +    P K+R T    P    +   P     
Sbjct: 884 ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARAT----PAPKGIPASP--SPK 937

Query: 358 GSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPA 414
           G+P PPA   P                   A P  P    K  P +P+   +PT PA
Sbjct: 938 GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP----KGGPATPSPKGAPTPPA 990


>gi|157502169 astacin-like metalloendopeptidase [Homo sapiens]
          Length = 431

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 18/121 (14%)

Query: 147 SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSP-- 204
           S+ RSP+ A+LSL  L             +LS+ S + + S   +      A P  SP  
Sbjct: 297 STGRSPAPASLSLQRL-----------LEALSAESRSPDPSGSSAGGQPVPAGPGESPHG 345

Query: 205 WQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCN 264
           W+SP +   + +     P+     TL  SPR  P         E+SWL   S++P  P +
Sbjct: 346 WESPALKKLSAEASARQPQ-----TLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSS 400

Query: 265 K 265
           +
Sbjct: 401 E 401


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 68/258 (26%), Positives = 85/258 (32%), Gaps = 54/258 (20%)

Query: 2    PSTSFPVPSKFPLG-----PAAAVFGRGETLG-PAPRAGGTMKSAEEEHYGYASSNVSPA 55
            P    P P  +P G     PA   F  G   G PAPR G   +   + H   A     P 
Sbjct: 914  PPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQ 973

Query: 56   LPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPAL 115
             PLP  H  L  P        PG++PP    S Y  A   G  G      HT+    PA 
Sbjct: 974  QPLPLQHPHLFPP------QAPGLLPP---QSPYPYAPQPGVLGQPPPPLHTQLYPGPA- 1023

Query: 116  ESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSK-----RSPSTATLSLPSLEAYRDPSC 170
                                      +D LP+        SP       P L     PS 
Sbjct: 1024 --------------------------QDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPST 1057

Query: 171  --LSP-ASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGA 227
              + P A+ L+ R  +S   S  S +  P  +P   P   P   P   +P     RG  A
Sbjct: 1058 RPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVP-PRPPAAEPPPCLRRGAAA 1116

Query: 228  CTLLGS---PRHSPSTSP 242
              LL S    +H  + SP
Sbjct: 1117 ADLLSSSPESQHGGTQSP 1134


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 68/312 (21%), Positives = 94/312 (30%), Gaps = 38/312 (12%)

Query: 27   LGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHP 86
            LGP   AG T                SP  P P      PA             PP   P
Sbjct: 958  LGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTA--------PPTPSP 1009

Query: 87   SGYGAALDGGPAGYFLSSGHTR----------------PDGAPALESPRIEITSCLGLYH 130
               G +   GP G  L+S  +R                PD +P    P       L L  
Sbjct: 1010 ---GPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLIL-- 1064

Query: 131  NNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRS--------- 181
             +  F        V+P+    PS   L     E   DPS  S  +SLS  S         
Sbjct: 1065 TSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTT 1124

Query: 182  CNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTS 241
             + + + Y S  S    SP  SP   P  +P  T   +         T        P+T+
Sbjct: 1125 PDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTT 1184

Query: 242  PRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWL 301
            P  +    S +    +    P     +S     P  +P    T  P  +P  +    +  
Sbjct: 1185 PHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTT 1244

Query: 302  GNTTQYTSSAIV 313
             + T  T S ++
Sbjct: 1245 PHPTTITHSTMI 1256



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 42/176 (23%), Positives = 64/176 (36%), Gaps = 14/176 (7%)

Query: 199  SPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSR 258
            SP T        SP+   PE   PR     T   +P   PS SP         L + SSR
Sbjct: 972  SPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPA---LTSDSSR 1028

Query: 259  PASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINA 318
              +P +          P  SP  +P P+   +P + +T   +  +T     S++V A+  
Sbjct: 1029 ELTPHSALTSEATSDAPDTSP-PTPDPASRTNPDLILTSPDFALST---PDSSVVPALTP 1084

Query: 319  LTTDSSLDLGDGVPVKSRKTTLE-QPPSVALKVEPVGEDLGSPPPPADFAPEDYSS 373
              + + L      P   ++ T +   PS    + P  E +       D     YSS
Sbjct: 1085 EPSPTPL------PTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSS 1134


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,282,173
Number of Sequences: 37866
Number of extensions: 1988555
Number of successful extensions: 7177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 267
Number of HSP's that attempted gapping in prelim test: 6372
Number of HSP's gapped (non-prelim): 840
length of query: 716
length of database: 18,247,518
effective HSP length: 109
effective length of query: 607
effective length of database: 14,120,124
effective search space: 8570915268
effective search space used: 8570915268
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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