BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|27436962 potassium voltage-gated channel, shaker-related subfamily, beta member 1 isoform 2 [Homo sapiens] (408 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|27436962 potassium voltage-gated channel, shaker-related subf... 823 0.0 gi|27436964 potassium voltage-gated channel, shaker-related subf... 680 0.0 gi|27436966 potassium voltage-gated channel, shaker-related subf... 673 0.0 gi|27436969 potassium voltage-gated channel, shaker-related subf... 591 e-169 gi|4504825 potassium voltage-gated channel, shaker-related subfa... 585 e-167 gi|27436971 potassium voltage-gated channel, shaker-related subf... 526 e-149 gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s... 84 3e-16 gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens] 81 2e-15 gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens] 80 3e-15 gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s... 61 2e-09 gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens] 45 1e-04 gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens] 44 2e-04 gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens] 44 2e-04 gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] 42 0.001 gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] 42 0.001 gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] 39 0.006 gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens] 39 0.008 gi|122937516 aldo-keto reductase family 1, member B10-like [Homo... 37 0.042 gi|207028673 hypothetical protein LOC100134257 [Homo sapiens] 35 0.12 gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] 33 0.47 gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens] 31 2.3 gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens] 31 2.3 gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 29 8.8 gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 29 8.8 gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 29 8.8 >gi|27436962 potassium voltage-gated channel, shaker-related subfamily, beta member 1 isoform 2 [Homo sapiens] Length = 408 Score = 823 bits (2126), Expect = 0.0 Identities = 408/408 (100%), Positives = 408/408 (100%) Query: 1 MHLYKPACADIPSPKLGLPKSSESALKCRWHLAVTKTQPQAACKPVRPSGAAEQKYVEKF 60 MHLYKPACADIPSPKLGLPKSSESALKCRWHLAVTKTQPQAACKPVRPSGAAEQKYVEKF Sbjct: 1 MHLYKPACADIPSPKLGLPKSSESALKCRWHLAVTKTQPQAACKPVRPSGAAEQKYVEKF 60 Query: 61 LRVHGISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYES 120 LRVHGISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYES Sbjct: 61 LRVHGISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYES 120 Query: 121 GVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG 180 GVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG Sbjct: 121 GVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEG 180 Query: 181 LKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAY 240 LKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAY Sbjct: 181 LKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAY 240 Query: 241 SVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGV 300 SVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGV Sbjct: 241 SVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGV 300 Query: 301 PESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSS 360 PESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSS Sbjct: 301 PESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSS 360 Query: 361 VLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 408 VLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS Sbjct: 361 VLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 408 >gi|27436964 potassium voltage-gated channel, shaker-related subfamily, beta member 1 isoform 3 [Homo sapiens] Length = 401 Score = 680 bits (1755), Expect = 0.0 Identities = 339/349 (97%), Positives = 342/349 (97%) Query: 60 FLRVHGISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE 119 F H ISL+E+T +TGM YRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE Sbjct: 53 FTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE 112 Query: 120 SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE 179 SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE Sbjct: 113 SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE 172 Query: 180 GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA 239 GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA Sbjct: 173 GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA 232 Query: 240 YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG 299 YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG Sbjct: 233 YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG 292 Query: 300 VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS 359 VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS Sbjct: 293 VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS 352 Query: 360 SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 408 SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS Sbjct: 353 SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 401 >gi|27436966 potassium voltage-gated channel, shaker-related subfamily, beta member 1 isoform 1 [Homo sapiens] Length = 419 Score = 673 bits (1737), Expect = 0.0 Identities = 335/349 (95%), Positives = 341/349 (97%) Query: 60 FLRVHGISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE 119 +L++ +S + TT TGM +RNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE Sbjct: 71 YLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE 130 Query: 120 SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE 179 SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE Sbjct: 131 SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE 190 Query: 180 GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA 239 GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA Sbjct: 191 GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA 250 Query: 240 YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG 299 YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG Sbjct: 251 YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG 310 Query: 300 VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS 359 VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS Sbjct: 311 VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS 370 Query: 360 SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 408 SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS Sbjct: 371 SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 419 >gi|27436969 potassium voltage-gated channel, shaker-related subfamily, beta member 2 isoform 2 [Homo sapiens] Length = 353 Score = 591 bits (1523), Expect = e-169 Identities = 283/343 (82%), Positives = 322/343 (93%), Gaps = 2/343 (0%) Query: 66 ISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLF 125 +SL++T GM YRNLGKSGLRVSCLGLGTWVTFGGQI+DE+AE+LMT+AY++G+NLF Sbjct: 13 LSLRQT--GSPGMIYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLF 70 Query: 126 DTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSL 185 DTAEVYAAGKAEV+LG+IIKKKGWRRSSLVITTK++WGGKAETERGLSRKHIIEGLK SL Sbjct: 71 DTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASL 130 Query: 186 QRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQ 245 +RLQLEYVDVVFANRPD NTPMEE VRAMTHVINQGMAMYWGTSRWS+MEIMEAYSVARQ Sbjct: 131 ERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQ 190 Query: 246 FNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSR 305 FN+ PP+CEQAEYH+FQREKVEVQLPEL+HKIGVGAMTWSPLACGI+SGKY +G+P SR Sbjct: 191 FNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSR 250 Query: 306 ASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGS 365 ASLK YQWLK++I+SEEGR+QQ KLK+L IAERLGCTLPQLA+AWCLRNEGVSSVLLG+ Sbjct: 251 ASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGA 310 Query: 366 STPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 408 S +QL+EN+GAIQVLPK++S +++EID+IL NKPYSKKDYRS Sbjct: 311 SNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS 353 >gi|4504825 potassium voltage-gated channel, shaker-related subfamily, beta member 2 isoform 1 [Homo sapiens] Length = 367 Score = 585 bits (1509), Expect = e-167 Identities = 278/329 (84%), Positives = 314/329 (95%) Query: 80 YRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVI 139 YRNLGKSGLRVSCLGLGTWVTFGGQI+DE+AE+LMT+AY++G+NLFDTAEVYAAGKAEV+ Sbjct: 39 YRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVV 98 Query: 140 LGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFAN 199 LG+IIKKKGWRRSSLVITTK++WGGKAETERGLSRKHIIEGLK SL+RLQLEYVDVVFAN Sbjct: 99 LGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFAN 158 Query: 200 RPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYH 259 RPD NTPMEE VRAMTHVINQGMAMYWGTSRWS+MEIMEAYSVARQFN+ PP+CEQAEYH Sbjct: 159 RPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYH 218 Query: 260 LFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIV 319 +FQREKVEVQLPEL+HKIGVGAMTWSPLACGI+SGKY +G+P SRASLK YQWLK++I+ Sbjct: 219 MFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKIL 278 Query: 320 SEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQ 379 SEEGR+QQ KLK+L IAERLGCTLPQLA+AWCLRNEGVSSVLLG+S +QL+EN+GAIQ Sbjct: 279 SEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQ 338 Query: 380 VLPKMTSHVVNEIDNILRNKPYSKKDYRS 408 VLPK++S +++EID+IL NKPYSKKDYRS Sbjct: 339 VLPKLSSSIIHEIDSILGNKPYSKKDYRS 367 >gi|27436971 potassium voltage-gated channel, shaker-related subfamily, beta member 3 [Homo sapiens] Length = 404 Score = 526 bits (1355), Expect = e-149 Identities = 252/338 (74%), Positives = 298/338 (88%) Query: 67 SLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFD 126 +L+E+T TGM YRNLGKSGLRVSCLGLGTWVTFG QISDE AE ++T+AYE GVNLFD Sbjct: 67 ALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFD 126 Query: 127 TAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQ 186 TAEVYAAGKAE LG+I+K KGWRRSS VITTK++WGG+AETERGLSRKHIIEGL+GSL+ Sbjct: 127 TAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLE 186 Query: 187 RLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQF 246 RLQL YVD+VFANR D N PMEEIVRAMT+VINQG+A+YWGTSRW A EIMEAYS+ARQF Sbjct: 187 RLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQF 246 Query: 247 NMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRA 306 N+IPPVCEQAE+HLFQREKVE+QLPELYHKIGVG++TW PLACG+I+ KY VP++ RA Sbjct: 247 NLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRVPDTCRA 306 Query: 307 SLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSS 366 S+K YQWLK+++ SE+G+KQQ K+ DL P+A +LGCT+ QLA+AWCLR+EGVSSVLLG S Sbjct: 307 SIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLRSEGVSSVLLGVS 366 Query: 367 TPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKK 404 + EQLIE+LGA+QVL ++T V EID +L NKP+SKK Sbjct: 367 SAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPHSKK 404 >gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo sapiens] Length = 331 Score = 83.6 bits (205), Expect = 3e-16 Identities = 78/296 (26%), Positives = 138/296 (46%), Gaps = 25/296 (8%) Query: 103 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 161 G+ D +T A+ E G DTA +Y+ G++E ILG + + G + I TK Sbjct: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKAN 79 Query: 162 -WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQ 220 W G + L + L+ SL+RLQ VD+ + + PD + P+EE +RA + + Sbjct: 80 PWIGNS-----LKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQE 134 Query: 221 GMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVG 280 G + G S ++A E+ E ++ + I P Q Y R+ VE +L G+ Sbjct: 135 GKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQ-VETELFPCLRHFGLR 193 Query: 281 AMTWSPLACGIISGKYGNGVPESSRASLKCY--QWLKERIVSEEGRKQQNKLKDLSPIAE 338 ++PLA G+++GKY + + + + QW + + +++ + ++ + + Sbjct: 194 FYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGTQWAE---IYRNHFWKEHHFEGIALVEK 250 Query: 339 RL----GCTLPQL---AVAWC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 382 L G + P + A+ W L+ +V+LG S+ EQL +NL A + P Sbjct: 251 ALQAAYGASAPSMTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306 >gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens] Length = 331 Score = 80.9 bits (198), Expect = 2e-15 Identities = 80/293 (27%), Positives = 130/293 (44%), Gaps = 19/293 (6%) Query: 103 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 161 G+ D +T A+ E G DTA VY+ G++E ILG + + G + I TK Sbjct: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI 79 Query: 162 WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQG 221 L + L+ SL+RLQ VD+ + + PD +TP+EE +RA + +G Sbjct: 80 ----PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEG 135 Query: 222 MAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGA 281 + G S ++A E+ E ++ + I P Q Y+ R+ VE +L G+ Sbjct: 136 KFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VETELFPCLRHFGLRF 194 Query: 282 MTWSPLACGIISGKY----GNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIA 337 ++PLA G+++GKY NG R + + +E + L + + Sbjct: 195 YAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVE-KALQ 253 Query: 338 ERLGCTLPQLAVA---WC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 382 G + P + A W L+ +V+LG S+ EQL +NL A + P Sbjct: 254 AAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306 >gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens] Length = 359 Score = 80.1 bits (196), Expect = 3e-15 Identities = 77/282 (27%), Positives = 126/282 (44%), Gaps = 30/282 (10%) Query: 119 ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY-WGGKAETERGLSRKHI 177 E G DTA +Y+ G++E ILG + G + I TK W GK+ L + Sbjct: 65 ERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKS-----LKPDSV 119 Query: 178 IEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIM 237 L+ SL+RLQ VD+ + + PD TP+EE + A + +G + G S +++ E+ Sbjct: 120 RSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVA 179 Query: 238 EAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYG 297 E ++ + I P Q Y+ R+ VE +L G+ ++PLA G+++GKY Sbjct: 180 EICTLCKSNGWILPTVYQGMYNATTRQ-VETELFPCLRHFGLRFYAYNPLAGGLLTGKYK 238 Query: 298 NGVPESSRASLKCY--QWLKERIVSEEGRKQQNKLKDLSPIA-------ERLGCTLPQL- 347 + + + + W +E R + K IA G + P + Sbjct: 239 YEDKDGKQPVGRFFGNSW------AETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVT 292 Query: 348 --AVAWC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 382 A+ W L+ +V+LG S+ EQL +NL A + P Sbjct: 293 SAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGP 334 >gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo sapiens] Length = 249 Score = 61.2 bits (147), Expect = 2e-09 Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 7/155 (4%) Query: 103 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 161 G+ D +T A+ E G DTA +Y+ G++E ILG + + G + I TK Sbjct: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKAN 79 Query: 162 -WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQ 220 W G + L + L+ SL+RLQ VD+ + + PD + P+EE +RA + + Sbjct: 80 PWIGNS-----LKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQE 134 Query: 221 GMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQ 255 G + G S ++A E+ E ++ + I P Q Sbjct: 135 GKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169 >gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens] Length = 316 Score = 45.1 bits (105), Expect = 1e-04 Identities = 53/234 (22%), Positives = 100/234 (42%), Gaps = 45/234 (19%) Query: 78 MAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA-AGKA 136 MA R L +G ++ LGLGTW + GQ+++ V +A + G D A VY + Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAV-----KVAIDVGYRHIDCAHVYQNENEV 55 Query: 137 EVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR----LQLEY 192 V + ++++ +R L I +KL+ E+GL +KG+ Q+ L+L+Y Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWC---TYHEKGL--------VKGACQKTLSDLKLDY 104 Query: 193 VDVVFANRPDSNTPMEEIV-------------------RAMTHVINQGMAMYWGTSRWSA 233 +D+ + P P +E AM ++++G+ G S ++ Sbjct: 105 LDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNH 164 Query: 234 MEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPL 287 +++ + + P Q E H + ++ +L + G+ +SPL Sbjct: 165 LQV--EMILNKPGLKYKPAVNQIECHPYLTQE---KLIQYCQSKGIVVTAYSPL 213 >gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens] Length = 325 Score = 44.3 bits (103), Expect = 2e-04 Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 43/198 (21%) Query: 86 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 145 +G ++ +GLGTW + GQ+ V A G D A +Y E +G +K Sbjct: 10 TGQKMPLIGLGTWKSEPGQVKAAV-----KYALSVGYRHIDCAAIYG---NEPEIGEALK 61 Query: 146 K-----KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 200 + K R L +T+KL W K E + L+ +L LQLEY+D+ + Sbjct: 62 EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114 Query: 201 PDS-------------------NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 241 P + +T +E +A+ ++ +G+ G S +++ +I + S Sbjct: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174 Query: 242 VARQFNMIPPVCEQAEYH 259 VA + P Q E H Sbjct: 175 VA----SVRPAVLQVECH 188 >gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens] Length = 325 Score = 44.3 bits (103), Expect = 2e-04 Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 43/198 (21%) Query: 86 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 145 +G ++ +GLGTW + GQ+ V A G D A +Y E +G +K Sbjct: 10 TGQKMPLIGLGTWKSEPGQVKAAV-----KYALSVGYRHIDCAAIYG---NEPEIGEALK 61 Query: 146 K-----KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 200 + K R L +T+KL W K E + L+ +L LQLEY+D+ + Sbjct: 62 EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114 Query: 201 PDS-------------------NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 241 P + +T +E +A+ ++ +G+ G S +++ +I + S Sbjct: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174 Query: 242 VARQFNMIPPVCEQAEYH 259 VA + P Q E H Sbjct: 175 VA----SVRPAVLQVECH 188 >gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] Length = 323 Score = 42.0 bits (97), Expect = 0.001 Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%) Query: 93 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 148 LG GT+ ++ A + +A E+G + D+A VY E +G I+ K Sbjct: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73 Query: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 208 +R + T+KL W E + L+ SL+ LQL+YVD+ + P S P E Sbjct: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126 Query: 209 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 248 E++ ++ + + T + W AME + +A+ + Sbjct: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181 Query: 249 --IPPVCEQAEYHLFQREK 265 PVC Q E H + ++ Sbjct: 182 LKYKPVCNQVECHPYFNQR 200 >gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] Length = 323 Score = 42.0 bits (97), Expect = 0.001 Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%) Query: 93 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 148 LG GT+ ++ A + +A E+G + D+A VY E +G I+ K Sbjct: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73 Query: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 208 +R + T+KL W E + L+ SL+ LQL+YVD+ + P S P E Sbjct: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126 Query: 209 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 248 E++ ++ + + T + W AME + +A+ + Sbjct: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181 Query: 249 --IPPVCEQAEYHLFQREK 265 PVC Q E H + ++ Sbjct: 182 LKYKPVCNQVECHPYFNQR 200 >gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] Length = 323 Score = 39.3 bits (90), Expect = 0.006 Identities = 50/199 (25%), Positives = 81/199 (40%), Gaps = 43/199 (21%) Query: 93 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 148 LG GT+ ++ A +A E+G D+A +Y E +G I+ K Sbjct: 19 LGFGTYAP--AEVPKSKALEATKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73 Query: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 208 +R + T+KL W E + L+ SL+ LQL+YVD+ + P S P E Sbjct: 74 VKREDIFYTSKL-WCNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126 Query: 209 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVA----------RQFNMI----- 249 E++ ++ + + T + W A+E + +A RQ MI Sbjct: 127 EVIPK-----DENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181 Query: 250 ---PPVCEQAEYHLFQREK 265 PVC Q E H + ++ Sbjct: 182 LKYKPVCNQVECHPYFNQR 200 >gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens] Length = 323 Score = 38.9 bits (89), Expect = 0.008 Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 44/201 (21%) Query: 93 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 148 LG GT+ ++ A + +A E+G D+A +Y E +G I+ K Sbjct: 19 LGFGTYAP--PEVPRSKALEVTKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73 Query: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIE-GLKGSLQRLQLEYVDVVFANRPDSNTPM 207 +R + T+KL+ R ++ L+ SL++ QL+YVD+ + P S P Sbjct: 74 VKREDIFYTSKLW--------STFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125 Query: 208 EEIVRAMTHVINQGMAMYWGT---SRWSAMEIMEAYSVA----------RQFNMI----- 249 EE ++ G ++ + W AME + +A RQ MI Sbjct: 126 EE----LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181 Query: 250 ---PPVCEQAEYH-LFQREKV 266 PVC Q E H F R K+ Sbjct: 182 LKYKPVCNQVECHPYFNRSKL 202 >gi|122937516 aldo-keto reductase family 1, member B10-like [Homo sapiens] Length = 316 Score = 36.6 bits (83), Expect = 0.042 Identities = 50/220 (22%), Positives = 92/220 (41%), Gaps = 39/220 (17%) Query: 89 RVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEV--ILGSIIKK 146 ++ +GLGTW + G++ + V +A ++ D A Y + EV + I++ Sbjct: 12 KMPIVGLGTWRSLLGKVKEAV-----KVAIDAEYRHIDCAYFY-ENQHEVGEAIQEKIQE 65 Query: 147 KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP----- 201 K R L I +K++ ER L RK + +L+ L+L Y+DV + P Sbjct: 66 KAVMREDLFIVSKVW---PTFFERPLVRK----AFEKTLKDLKLSYLDVYLIHWPQGFKT 118 Query: 202 -DSNTPME-------------EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFN 247 D P + + AM ++++G+ G S ++ +I + + Sbjct: 119 GDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLN--KPGL 176 Query: 248 MIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPL 287 PV Q E H + ++ +L + H G+ +SPL Sbjct: 177 KYKPVTNQVECHPYLTQE---KLIQYCHSKGITVTAYSPL 213 >gi|207028673 hypothetical protein LOC100134257 [Homo sapiens] Length = 139 Score = 35.0 bits (79), Expect = 0.12 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 16/115 (13%) Query: 93 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 148 LG GT+ ++ A + +A E+G + D+A VY E +G I+ K Sbjct: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73 Query: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDS 203 +R + T+KL W E + L+ SL+ LQL+YVD+ + P S Sbjct: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVS 121 >gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] Length = 323 Score = 33.1 bits (74), Expect = 0.47 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 47/195 (24%) Query: 93 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 148 LG GT+ ++ A + +A E+G D+A +Y E +G I+ K Sbjct: 19 LGFGTYAP--PEVPRNRAVEVTKLAIEAGFRHIDSAYLY---NNEEQVGLAIRSKIADGS 73 Query: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP------D 202 +R + T+KL+ + + L+ SL++LQL+YVD+ + P + Sbjct: 74 VKREDIFYTSKLWC-------TFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126 Query: 203 SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVA----------RQFNMI--- 249 + P +E + + ++ ++ W ME + +A RQ MI Sbjct: 127 TPLPKDENGKVIFDTVDL-------SATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179 Query: 250 -----PPVCEQAEYH 259 PVC Q E H Sbjct: 180 PGLKYKPVCNQVECH 194 >gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens] Length = 758 Score = 30.8 bits (68), Expect = 2.3 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 281 AMTWSPLACGIISGKYGNGV-PESSRASLKCYQWLKERIVSEEGRKQQNKL 330 A +WSP + S G P ++ A+L Q L+ER+ E RKQQ +L Sbjct: 106 ARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEEL 156 >gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens] Length = 758 Score = 30.8 bits (68), Expect = 2.3 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 281 AMTWSPLACGIISGKYGNGV-PESSRASLKCYQWLKERIVSEEGRKQQNKL 330 A +WSP + S G P ++ A+L Q L+ER+ E RKQQ +L Sbjct: 106 ARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEEL 156 >gi|163310749 LIM and calponin homology domains 1 isoform e [Homo sapiens] Length = 890 Score = 28.9 bits (63), Expect = 8.8 Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 264 EKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEG 323 E ++ LP L ++ + SP+ K+ PE R + +Q +ER++ E Sbjct: 569 EANQLHLPNLNSQVDSPSSEKSPVMTPF---KFWAWDPEEERRRQEKWQQEQERLLQERY 625 Query: 324 RKQQNKLKD 332 +K+Q+KLK+ Sbjct: 626 QKEQDKLKE 634 >gi|163310747 LIM and calponin homology domains 1 isoform d [Homo sapiens] Length = 902 Score = 28.9 bits (63), Expect = 8.8 Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 264 EKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEG 323 E ++ LP L ++ + SP+ K+ PE R + +Q +ER++ E Sbjct: 581 EANQLHLPNLNSQVDSPSSEKSPVMTPF---KFWAWDPEEERRRQEKWQQEQERLLQERY 637 Query: 324 RKQQNKLKD 332 +K+Q+KLK+ Sbjct: 638 QKEQDKLKE 646 >gi|163310745 LIM and calponin homology domains 1 isoform c [Homo sapiens] Length = 1056 Score = 28.9 bits (63), Expect = 8.8 Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 264 EKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEG 323 E ++ LP L ++ + SP+ K+ PE R + +Q +ER++ E Sbjct: 735 EANQLHLPNLNSQVDSPSSEKSPVMTPF---KFWAWDPEEERRRQEKWQQEQERLLQERY 791 Query: 324 RKQQNKLKD 332 +K+Q+KLK+ Sbjct: 792 QKEQDKLKE 800 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.132 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,081,791 Number of Sequences: 37866 Number of extensions: 643659 Number of successful extensions: 1392 Number of sequences better than 10.0: 25 Number of HSP's better than 10.0 without gapping: 14 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 1362 Number of HSP's gapped (non-prelim): 29 length of query: 408 length of database: 18,247,518 effective HSP length: 105 effective length of query: 303 effective length of database: 14,271,588 effective search space: 4324291164 effective search space used: 4324291164 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.