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Search of human proteins with 27436936
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a
[Homo sapiens]
(377 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 756 0.0
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 750 0.0
gi|4557489 cone-rod homeobox protein [Homo sapiens] 107 1e-23
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 102 7e-22
gi|24497589 aristaless related homeobox [Homo sapiens] 100 4e-21
gi|7706659 paired related homeobox 2 [Homo sapiens] 99 6e-21
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 99 8e-21
gi|46249382 paired-like homeobox 2a [Homo sapiens] 99 8e-21
gi|4826912 paired-like homeodomain 3 [Homo sapiens] 98 1e-20
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 96 4e-20
gi|12707580 paired-like homeobox 2b [Homo sapiens] 96 7e-20
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] 95 1e-19
gi|122937321 UNC homeobox [Homo sapiens] 94 2e-19
gi|24234708 paired-like homeodomain transcription factor 2 isofo... 93 3e-19
gi|21361183 paired-like homeodomain transcription factor 2 isofo... 93 4e-19
gi|24234711 paired-like homeodomain transcription factor 2 isofo... 93 4e-19
gi|34365783 visual system homeobox 2 [Homo sapiens] 92 6e-19
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 92 6e-19
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 92 6e-19
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 92 6e-19
gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens] 92 6e-19
gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 92 1e-18
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 92 1e-18
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens] 92 1e-18
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 92 1e-18
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 91 2e-18
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 91 2e-18
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 91 2e-18
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 91 2e-18
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 91 2e-18
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 756 bits (1952), Expect = 0.0
Identities = 377/377 (100%), Positives = 377/377 (100%)
Query: 1 MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLADIILEARYG 60
MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLADIILEARYG
Sbjct: 1 MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLADIILEARYG 60
Query: 61 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 120
SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK
Sbjct: 61 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 120
Query: 121 FRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSE 180
FRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSE
Sbjct: 121 FRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSE 180
Query: 181 QSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAP 240
QSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAP
Sbjct: 181 QSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAP 240
Query: 241 GGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAVPYL 300
GGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAVPYL
Sbjct: 241 GGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAAAVPYL 300
Query: 301 GVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLR 360
GVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLR
Sbjct: 301 GVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTSIENLR 360
Query: 361 LRAKQHAASLGLDTLPN 377
LRAKQHAASLGLDTLPN
Sbjct: 361 LRAKQHAASLGLDTLPN 377
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 750 bits (1936), Expect = 0.0
Identities = 377/382 (98%), Positives = 377/382 (98%), Gaps = 5/382 (1%)
Query: 1 MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLA-----DIIL 55
MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLA DIIL
Sbjct: 1 MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIIL 60
Query: 56 EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFK 115
EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFK
Sbjct: 61 EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFK 120
Query: 116 NRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH 175
NRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH
Sbjct: 121 NRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH 180
Query: 176 LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTI 235
LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTI
Sbjct: 181 LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTI 240
Query: 236 TPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAA 295
TPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAA
Sbjct: 241 TPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAA 300
Query: 296 AVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTS 355
AVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTS
Sbjct: 301 AVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTS 360
Query: 356 IENLRLRAKQHAASLGLDTLPN 377
IENLRLRAKQHAASLGLDTLPN
Sbjct: 361 IENLRLRAKQHAASLGLDTLPN 382
>gi|4557489 cone-rod homeobox protein [Homo sapiens]
Length = 299
Score = 107 bits (268), Expect = 1e-23
Identities = 89/247 (36%), Positives = 122/247 (49%), Gaps = 33/247 (13%)
Query: 40 SVHALTLAERLADIILEA-RYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRER 98
SV+AL L+ D++ +A Y S RKQRR RT FT QLE LE F KT YPDV RE
Sbjct: 12 SVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREE 71
Query: 99 LAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKA-EAPTPDTQL 157
+A+ NLPE+RVQVWFKNRRAK R++++ +++Q +A+ + KA +P P T +
Sbjct: 72 VALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDV 131
Query: 158 --------DTEQPPRLP---GSDPPAELHLSLSEQSASESAPEDQ--------PDREEDP 198
D+ PP LP GS A +S+ ++ PE Q P P
Sbjct: 132 CPDPLGISDSYSPP-LPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAP 190
Query: 199 --------RAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLLGPSHS 250
A P A SP + GL SP G ++P++ G +GPS +
Sbjct: 191 YAMTYAPASAFCSSPSAYGSPSSYFSGLD-PYLSPMVPQLGGPALSPLS--GPSVGPSLA 247
Query: 251 YSSSPLS 257
S + LS
Sbjct: 248 QSPTSLS 254
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 102 bits (253), Expect = 7e-22
Identities = 94/299 (31%), Positives = 123/299 (41%), Gaps = 71/299 (23%)
Query: 59 YGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRR 118
Y + RKQRR RT FT QL+ LE F KT YPD+ MRE +A+ NLPE+RVQVWFKNRR
Sbjct: 31 YPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRR 90
Query: 119 AKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSL 178
AK R++Q+S G G T+ P S P +
Sbjct: 91 AKCRQQQQS----------------GSG------------TKSRPAKKKSSP-------V 115
Query: 179 SEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPV 238
E S SES +G P A S + S +P A + L PV
Sbjct: 116 RESSGSES-------------SGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPV 162
Query: 239 APGGGLLGPSHSYSSSPLSL----FRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAA 294
A L P+ S SP S+ + +AA +N +S A AA AA
Sbjct: 163 AAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSN----TSCMQRSVAAGAATAA 218
Query: 295 AAVP------------YLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAG 341
A+ P Y + + G + C SY + + HQ SP+ P+ AG
Sbjct: 219 ASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQ---LSPMAPSSMAG 274
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 99.8 bits (247), Expect = 4e-21
Identities = 104/322 (32%), Positives = 130/322 (40%), Gaps = 87/322 (27%)
Query: 56 EARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFK 115
++ G RKQRR RT FT+ QLE LE+ FQKTHYPDV RE LAM +L EARVQVWF+
Sbjct: 318 DSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQ 377
Query: 116 NRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH 175
NRRAK+RK++ KA A T PP LP P + H
Sbjct: 378 NRRAKWRKRE---------------------KAGAQT--------HPPGLPFPGPLSATH 408
Query: 176 LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTI 235
LS + P P + A A A + +
Sbjct: 409 -PLSPYLDASPFPPHHPALDSAWTAAA------------------------AAAAAAFPS 443
Query: 236 TPVAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFEVGGPAPAAAAAAA 295
P PG L P S +PL L S+F A +
Sbjct: 444 LPPPPGSASLPP----SGAPLGL--------------------STFLGAAVFRHPAFISP 479
Query: 296 AVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKTTS 355
A L MAPL S + +AAA Q A A PA+A + + +S
Sbjct: 480 AFGRLFSTMAPLTS--------ASTAAALLRQPTPAVEGAVASGALADPATAAADRRASS 531
Query: 356 IENLRLRAKQHAASL-GLDTLP 376
I LRL+AK+HAA L L+ LP
Sbjct: 532 IAALRLKAKEHAAQLTQLNILP 553
Score = 30.8 bits (68), Expect = 2.1
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 13/58 (22%)
Query: 284 GGPAPAAAAAAAAVPYLGVNMAPLGSL-HCQSYYQSLSAAAAAHQGVWGSPLLPAPPA 340
G A AAAAAAAA L ++ AP S+ +SY ++ G+P +P PPA
Sbjct: 143 GAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYREN------------GAPFVPPPPA 188
>gi|7706659 paired related homeobox 2 [Homo sapiens]
Length = 253
Score = 99.0 bits (245), Expect = 6e-21
Identities = 58/133 (43%), Positives = 78/133 (58%), Gaps = 12/133 (9%)
Query: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
+KQRR+RT F + QL+ALE+ F++THYPD +RE LA NL EARVQVWF+NRRAKFR+
Sbjct: 102 KKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRR 161
Query: 124 KQRSL---QKEQLQKQKEAEGSHGEGKAEAPT---PDTQLDTEQ------PPRLPGSDPP 171
+R++ + L K E + + A PT PD T PP PGS P
Sbjct: 162 NERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPYSTVPPYSPGSSGP 221
Query: 172 AELHLSLSEQSAS 184
A ++++ AS
Sbjct: 222 ATPGVNMANSIAS 234
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 98.6 bits (244), Expect = 8e-21
Identities = 48/74 (64%), Positives = 60/74 (81%)
Query: 61 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 120
S K+RR+RT FT+ QLE LEK FQKTHYPDV RE+LAM T+L EARVQVWF+NRRAK
Sbjct: 209 SNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAK 268
Query: 121 FRKKQRSLQKEQLQ 134
+RK++R Q +Q++
Sbjct: 269 WRKRERFGQMQQVR 282
Score = 33.9 bits (76), Expect = 0.25
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 13/87 (14%)
Query: 288 PAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASA 347
P + A++ +L V+ A GS Q++ SL AA+ G+ G L P
Sbjct: 338 PPGSGASSVTDFLSVSGA--GSHVGQTHMGSLFGAASLSPGLNGYELNGEP--------- 386
Query: 348 TLNSKTTSIENLRLRAKQHAASLGLDT 374
+ KT+SI LR++AK+H+A++ T
Sbjct: 387 --DRKTSSIAALRMKAKEHSAAISWAT 411
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 98.6 bits (244), Expect = 8e-21
Identities = 65/182 (35%), Positives = 84/182 (46%), Gaps = 26/182 (14%)
Query: 62 QHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKF 121
+ RKQRR RT FT+ QL+ LE+ F +THYPD+ RE LA+ +L EARVQVWF+NRRAKF
Sbjct: 86 EKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKF 145
Query: 122 RKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQ 181
RK++R+ K A G+ G K EA D S++
Sbjct: 146 RKQERA------ASAKGAAGAAGAKKGEARCSSEDDD--------------------SKE 179
Query: 182 SASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPG 241
S P+ P G P+ SP + G G G G+L G
Sbjct: 180 STCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGG 239
Query: 242 GG 243
GG
Sbjct: 240 GG 241
>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
Length = 302
Score = 97.8 bits (242), Expect = 1e-20
Identities = 84/246 (34%), Positives = 115/246 (46%), Gaps = 27/246 (10%)
Query: 60 GSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRA 119
GS +KQRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRA
Sbjct: 56 GSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRA 115
Query: 120 KFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLS 179
K+RK++RS Q E + A E P P L + P A +
Sbjct: 116 KWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL--APPLAAKTFPFA 173
Query: 180 EQSASESAPEDQP-DREEDPRAGAEDPKAEKSPG-----ADSKGLGCKRGSPKADSPGSL 233
S + QP A + P A +PG +GLG G P +P ++
Sbjct: 174 FNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLG---GGPPGLAPAAV 230
Query: 234 TITPVA-PGGGLLGPSHSYSSSPL--------SLFRLQEQFRQHMAATNNLVHYSSFEVG 284
+ V+ P + + +SSP SL L+ + +QH + + VH
Sbjct: 231 SSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVH------- 283
Query: 285 GPAPAA 290
GP PAA
Sbjct: 284 GPPPAA 289
Score = 32.7 bits (73), Expect = 0.55
Identities = 40/124 (32%), Positives = 52/124 (41%), Gaps = 33/124 (26%)
Query: 278 YSSFEVGGPAPAAAAAAAAVPYLGVNMAPLGSLHCQSYYQSL------SAAAA------- 324
Y ++ AP AA + VN+ PL S S S+ SAAAA
Sbjct: 153 YGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGP 212
Query: 325 -AHQGVWGSP--LLPA---------PPAGLAPASATLNSK--------TTSIENLRLRAK 364
A QG+ G P L PA P A A A+A S +S+ +LRL+AK
Sbjct: 213 GALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAK 272
Query: 365 QHAA 368
QHA+
Sbjct: 273 QHAS 276
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 96.3 bits (238), Expect = 4e-20
Identities = 54/104 (51%), Positives = 61/104 (58%), Gaps = 8/104 (7%)
Query: 60 GSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRA 119
G RKQRR+RT FT QQLEALE F +THYPDV RE LAM NL EARVQVWF+NRRA
Sbjct: 32 GFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRA 91
Query: 120 KFRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPP 163
K+RK +R + E E AE P + PP
Sbjct: 92 KWRKTERG--------ASDQEPGAKEPMAEVTPPPVRNINSPPP 127
Score = 32.0 bits (71), Expect = 0.94
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 13/99 (13%)
Query: 284 GGPAPAAAAAAAAVPYLGVNMAPLGS----------LHCQSYYQSLSAAAAAHQGVWGSP 333
G A + A A LG + P G L+ +Y Q+LS A+ G S
Sbjct: 128 GDQARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSC 187
Query: 334 LLPAPPAGLA--PASATLNSKTTSIENLRLRAKQHAASL 370
+P P GL+ P +++T S+ LR++A++H+ ++
Sbjct: 188 CVP-DPMGLSFLPTYGCQSNRTASVATLRMKAREHSEAV 225
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 95.5 bits (236), Expect = 7e-20
Identities = 67/198 (33%), Positives = 96/198 (48%), Gaps = 17/198 (8%)
Query: 61 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 120
++ RKQRR RT FT+ QL+ LE+ F +THYPD+ RE LA+ +L EARVQVWF+NRRAK
Sbjct: 93 NEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAK 152
Query: 121 FRKKQRSLQKEQLQKQ-----KEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELH 175
FRK++R+ + K+++ S + EA + D T P P P +
Sbjct: 153 FRKQERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPD-STGGPGPNPNPTPSCGAN 211
Query: 176 --------LSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPK- 226
+ + +A P +P + A A A + A + G G P
Sbjct: 212 GGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGGPGQ 271
Query: 227 --ADSPGSLTITPVAPGG 242
A PG +T P + GG
Sbjct: 272 GWAPGPGPITSIPDSLGG 289
>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
Length = 326
Score = 94.7 bits (234), Expect = 1e-19
Identities = 46/68 (67%), Positives = 56/68 (82%)
Query: 65 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKK 124
K+RR RT FT+ QLE LEK FQKTHYPDV +RE+LA+ T L EARVQVWF+NRRAK+RK+
Sbjct: 131 KKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKR 190
Query: 125 QRSLQKEQ 132
+R Q +Q
Sbjct: 191 ERYGQIQQ 198
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 94.4 bits (233), Expect = 2e-19
Identities = 78/264 (29%), Positives = 110/264 (41%), Gaps = 26/264 (9%)
Query: 65 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKK 124
K+RR+RT FT QLE LEK F ++HYPDV MRE LA+ +L E+RVQVWF+NRRAK+RKK
Sbjct: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
Query: 125 QRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAE--------LHL 176
+ + + + A SH + P ++ ++ ++ E HL
Sbjct: 164 ENT----KKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHL 219
Query: 177 SLSEQSASESAPEDQPDREE---DPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSL 233
+ SAP D P P A K PGA + G +P + P
Sbjct: 220 HSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPG 279
Query: 234 TITPV-----------APGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLVHYSSFE 282
T P P G + S P + E+ + + S
Sbjct: 280 TCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLS 339
Query: 283 VGGPAPAAAAAAAAVPYLGVNMAP 306
P AA+ AAA G++ AP
Sbjct: 340 DSPPRRKAASNAAAAAAAGLDFAP 363
>gi|24234708 paired-like homeodomain transcription factor 2 isoform
b [Homo sapiens]
Length = 317
Score = 93.2 bits (230), Expect = 3e-19
Identities = 47/107 (43%), Positives = 71/107 (66%)
Query: 25 QQAAQQAQHAPDYRPSVHALTLAERLADIILEARYGSQHRKQRRSRTAFTAQQLEALEKT 84
++ A ++ P P + +++ + + A S+ ++QRR RT FT+QQL+ LE T
Sbjct: 44 RKEAASSKFFPRQHPGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEAT 103
Query: 85 FQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKE 131
FQ+ YPD+ RE +A+ TNL EARV+VWFKNRRAK+RK++R+ Q E
Sbjct: 104 FQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAE 150
>gi|21361183 paired-like homeodomain transcription factor 2 isoform
c [Homo sapiens]
Length = 324
Score = 92.8 bits (229), Expect = 4e-19
Identities = 43/71 (60%), Positives = 57/71 (80%)
Query: 61 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 120
S+ ++QRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRAK
Sbjct: 87 SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 146
Query: 121 FRKKQRSLQKE 131
+RK++R+ Q E
Sbjct: 147 WRKRERNQQAE 157
Score = 32.0 bits (71), Expect = 0.94
Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 161 QPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEK 209
QP L S E+H ++S+ S+ E+A +D+ + ++ GAEDP +K
Sbjct: 43 QPRSLDSSKHRLEVH-TISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKK 90
>gi|24234711 paired-like homeodomain transcription factor 2 isoform
a [Homo sapiens]
Length = 271
Score = 92.8 bits (229), Expect = 4e-19
Identities = 43/71 (60%), Positives = 57/71 (80%)
Query: 61 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 120
S+ ++QRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRAK
Sbjct: 34 SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 93
Query: 121 FRKKQRSLQKE 131
+RK++R+ Q E
Sbjct: 94 WRKRERNQQAE 104
>gi|34365783 visual system homeobox 2 [Homo sapiens]
Length = 361
Score = 92.4 bits (228), Expect = 6e-19
Identities = 55/155 (35%), Positives = 88/155 (56%), Gaps = 3/155 (1%)
Query: 61 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 120
++ RK+RR RT FT+ QLE LEK F + HYPDV RE LAM T LPE R+QVWF+NRRAK
Sbjct: 143 TKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAK 202
Query: 121 FRKKQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSE 180
+RK+++ + + + G+ + P P++ L + + + P S
Sbjct: 203 WRKREKCWGRSSVMAEYGLYGA--MVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSL 260
Query: 181 QSASESAPEDQPDREEDPRAGAEDPKAEKSPGADS 215
++A+ES + + +R+ P+ + + E+ P A +
Sbjct: 261 EAAAESGRKPEGERQALPKLDKME-QDERGPDAQA 294
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 92.4 bits (228), Expect = 6e-19
Identities = 43/61 (70%), Positives = 50/61 (81%)
Query: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
RKQRRSRT FTA+QLE LEK F++THYPD+ RE LA T L EARVQVWF NRRA++RK
Sbjct: 215 RKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRK 274
Query: 124 K 124
+
Sbjct: 275 Q 275
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 92.4 bits (228), Expect = 6e-19
Identities = 43/61 (70%), Positives = 50/61 (81%)
Query: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
RKQRRSRT FTA+QLE LEK F++THYPD+ RE LA T L EARVQVWF NRRA++RK
Sbjct: 213 RKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRK 272
Query: 124 K 124
+
Sbjct: 273 Q 273
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 92.4 bits (228), Expect = 6e-19
Identities = 43/61 (70%), Positives = 50/61 (81%)
Query: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
RKQRRSRT FTA+QLE LEK F++THYPD+ RE LA T L EARVQVWF NRRA++RK
Sbjct: 215 RKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRK 274
Query: 124 K 124
+
Sbjct: 275 Q 275
>gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]
Length = 289
Score = 92.4 bits (228), Expect = 6e-19
Identities = 62/166 (37%), Positives = 82/166 (49%), Gaps = 17/166 (10%)
Query: 40 SVHALTLAERLADIILEA-RYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRER 98
+V+ L+L D++ + Y + RKQRR RT FT QL+ LE F KT YPD+ MRE
Sbjct: 11 AVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREE 70
Query: 99 LAMCTNLPEARVQVWFKNRRAKFRKKQRSLQ----------KEQLQKQKEAEGSHGEGKA 148
+A+ NLPE+RVQVWFKNRRAK R++Q+ Q K++ +E G
Sbjct: 71 VALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQ 130
Query: 149 EAPTPDTQLDT----EQPPRL--PGSDPPAELHLSLSEQSASESAP 188
P T + T P + P S P LS S S P
Sbjct: 131 FTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYP 176
>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
sapiens]
Length = 314
Score = 91.7 bits (226), Expect = 1e-18
Identities = 42/69 (60%), Positives = 56/69 (81%)
Query: 61 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 120
++ +KQRR RT FT+QQL+ LE TFQ+ YPD+ MRE +A+ TNL E RV+VWFKNRRAK
Sbjct: 84 AKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAK 143
Query: 121 FRKKQRSLQ 129
+RK++R+ Q
Sbjct: 144 WRKRERNQQ 152
Score = 28.9 bits (63), Expect = 7.9
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 12/66 (18%)
Query: 161 QPPRLPGSDPPAELHLSLS-------EQSASESAPEDQPDREEDPRAGAEDPKAEKSPGA 213
+PP P D HL+ E SASES+ + P++E R G +PK + GA
Sbjct: 18 RPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKE---RGG--EPKGPEDSGA 72
Query: 214 DSKGLG 219
G G
Sbjct: 73 GGTGCG 78
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 91.7 bits (226), Expect = 1e-18
Identities = 43/62 (69%), Positives = 53/62 (85%)
Query: 65 KQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKK 124
K+RR+RT F+ QLE LEK FQKTHYPDV RE+LA+ T+L EARVQVWF+NRRAK+RK+
Sbjct: 152 KKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKR 211
Query: 125 QR 126
+R
Sbjct: 212 ER 213
>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
Length = 217
Score = 91.7 bits (226), Expect = 1e-18
Identities = 41/65 (63%), Positives = 53/65 (81%)
Query: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
RKQRR+RT F + QL+ALE+ F++THYPD +RE LA NL EARVQVWF+NRRAKFR+
Sbjct: 92 RKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRR 151
Query: 124 KQRSL 128
+R++
Sbjct: 152 NERAM 156
>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
Length = 245
Score = 91.7 bits (226), Expect = 1e-18
Identities = 41/65 (63%), Positives = 53/65 (81%)
Query: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
RKQRR+RT F + QL+ALE+ F++THYPD +RE LA NL EARVQVWF+NRRAKFR+
Sbjct: 92 RKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRR 151
Query: 124 KQRSL 128
+R++
Sbjct: 152 NERAM 156
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/134 (41%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
Query: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
RKQRRSRT FTA+QLE LE+ F++THYPD+ RE LA L EARVQVWF NRRA++R
Sbjct: 216 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWR- 274
Query: 124 KQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPG--SDPPAELH--LSLS 179
KQ + G PT + QP +P SDP + +H L
Sbjct: 275 KQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLP 334
Query: 180 EQSASESAPEDQPD 193
+ +S PD
Sbjct: 335 PSTVHQSTIPSNPD 348
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/134 (41%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
Query: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
RKQRRSRT FTA+QLE LE+ F++THYPD+ RE LA L EARVQVWF NRRA++R
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWR- 275
Query: 124 KQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPG--SDPPAELH--LSLS 179
KQ + G PT + QP +P SDP + +H L
Sbjct: 276 KQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLP 335
Query: 180 EQSASESAPEDQPD 193
+ +S PD
Sbjct: 336 PSTVHQSTIPSNPD 349
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/134 (41%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
Query: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
RKQRRSRT FTA+QLE LE+ F++THYPD+ RE LA L EARVQVWF NRRA++R
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWR- 275
Query: 124 KQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPG--SDPPAELH--LSLS 179
KQ + G PT + QP +P SDP + +H L
Sbjct: 276 KQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLP 335
Query: 180 EQSASESAPEDQPD 193
+ +S PD
Sbjct: 336 PSTVHQSTIPSNPD 349
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/134 (41%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
Query: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
RKQRRSRT FTA+QLE LE+ F++THYPD+ RE LA L EARVQVWF NRRA++R
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWR- 275
Query: 124 KQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPG--SDPPAELH--LSLS 179
KQ + G PT + QP +P SDP + +H L
Sbjct: 276 KQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLP 335
Query: 180 EQSASESAPEDQPD 193
+ +S PD
Sbjct: 336 PSTVHQSTIPSNPD 349
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/134 (41%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
Query: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
RKQRRSRT FTA+QLE LE+ F++THYPD+ RE LA L EARVQVWF NRRA++R
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWR- 275
Query: 124 KQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPG--SDPPAELH--LSLS 179
KQ + G PT + QP +P SDP + +H L
Sbjct: 276 KQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLP 335
Query: 180 EQSASESAPEDQPD 193
+ +S PD
Sbjct: 336 PSTVHQSTIPSNPD 349
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,663,137
Number of Sequences: 37866
Number of extensions: 905285
Number of successful extensions: 7029
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 340
Number of HSP's successfully gapped in prelim test: 489
Number of HSP's that attempted gapping in prelim test: 5799
Number of HSP's gapped (non-prelim): 1685
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.