Guide to the Human Genome
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Search of human proteins with 27414491

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27414491 coiled-coil domain containing 28A [Homo sapiens]
         (274 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27414491 coiled-coil domain containing 28A [Homo sapiens]          540   e-154
gi|110349769 coiled-coil domain containing 28B [Homo sapiens]         172   3e-43
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     36   0.032
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         33   0.27 
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         33   0.27 
gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]              33   0.35 
gi|20544168 histone cluster 1, H1t [Homo sapiens]                      33   0.35 
gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]              33   0.35 
gi|41872583 Rho-associated, coiled-coil containing protein kinas...    32   0.60 
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    32   0.60 
gi|56550043 sarcolemma associated protein [Homo sapiens]               32   0.60 
gi|27881501 ATP-binding cassette, sub-family A, member 12 isofor...    32   0.78 
gi|30795238 ATP-binding cassette, sub-family A, member 12 isofor...    32   0.78 
gi|126362971 serine/threonine kinase 10 [Homo sapiens]                 31   1.0  
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    31   1.3  
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    31   1.3  
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    31   1.3  
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    31   1.3  
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    31   1.3  
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]      31   1.3  
gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]             30   1.7  
gi|10835073 N-myristoyltransferase 1 [Homo sapiens]                    30   1.7  
gi|56119214 GTPase, IMAP family member 6 [Homo sapiens]                30   1.7  
gi|18087819 hypothetical protein LOC91283 [Homo sapiens]               30   1.7  
gi|111038124 succinate dehydrogenase complex assembly factor 1 [...    30   2.3  
gi|165905591 LIM domain and actin binding 1 isoform c [Homo sapi...    30   2.3  
gi|165905589 LIM domain and actin binding 1 isoform a [Homo sapi...    30   2.3  
gi|7705373 LIM domain and actin binding 1 isoform b [Homo sapiens]     30   2.3  
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         30   2.3  
gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo s...    30   2.3  

>gi|27414491 coiled-coil domain containing 28A [Homo sapiens]
          Length = 274

 Score =  540 bits (1390), Expect = e-154
 Identities = 274/274 (100%), Positives = 274/274 (100%)

Query: 1   MPRAEPRATLGEQEKAGLPLGAWRLYLLRHFRKQTELRRSGSRDVTGALLVAAAVASEAV 60
           MPRAEPRATLGEQEKAGLPLGAWRLYLLRHFRKQTELRRSGSRDVTGALLVAAAVASEAV
Sbjct: 1   MPRAEPRATLGEQEKAGLPLGAWRLYLLRHFRKQTELRRSGSRDVTGALLVAAAVASEAV 60

Query: 61  GSLRVAEGGPNTLLLQVLRSWPWCNKELKTMEERKVKRRSPKSFSAHCTQVVNAKKNAIP 120
           GSLRVAEGGPNTLLLQVLRSWPWCNKELKTMEERKVKRRSPKSFSAHCTQVVNAKKNAIP
Sbjct: 61  GSLRVAEGGPNTLLLQVLRSWPWCNKELKTMEERKVKRRSPKSFSAHCTQVVNAKKNAIP 120

Query: 121 VSKSTGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQSTPIQHSFLTDVSDVQEMER 180
           VSKSTGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQSTPIQHSFLTDVSDVQEMER
Sbjct: 121 VSKSTGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQSTPIQHSFLTDVSDVQEMER 180

Query: 181 GLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKTASD 240
           GLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKTASD
Sbjct: 181 GLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKTASD 240

Query: 241 SNLDRLLSDLEELNSSIQKLHLADAQDVPNTSAS 274
           SNLDRLLSDLEELNSSIQKLHLADAQDVPNTSAS
Sbjct: 241 SNLDRLLSDLEELNSSIQKLHLADAQDVPNTSAS 274


>gi|110349769 coiled-coil domain containing 28B [Homo sapiens]
          Length = 200

 Score =  172 bits (436), Expect = 3e-43
 Identities = 104/202 (51%), Positives = 134/202 (66%), Gaps = 20/202 (9%)

Query: 91  MEERKVKRRSPKSFSAHCTQVVNAKKNAIPV----SKSTGFSNPASQSTSQRPKLKRVMK 146
           M+++K K+RSPK   A   Q     +  +PV    S S     P   S  QR K KRV K
Sbjct: 1   MDDKK-KKRSPKPCLAQPAQAPGTLRR-VPVPTSHSGSLALGLPHLPSPKQRAKFKRVGK 58

Query: 147 EKTKPQ-GGEGKGAQSTPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQ 205
           EK +P   G G G+  TP+QHSFLT+V+DV EME GLL+LLNDFHSG+LQAFG ECS EQ
Sbjct: 59  EKCRPVLAGGGSGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQ 118

Query: 206 MEHVRGMQEKLARL--NLELYGELEE-----------LPEDKRKTASDSNLDRLLSDLEE 252
           +EHVR MQEKLARL  +L++ GE E+           LPE+++KT +D NLD+LLS+LE+
Sbjct: 119 LEHVREMQEKLARLHFSLDVCGEEEDDEEEEDGVTEGLPEEQKKTMADRNLDQLLSNLED 178

Query: 253 LNSSIQKLHLADAQDVPNTSAS 274
           L++SIQKLHLA+  +    SA+
Sbjct: 179 LSNSIQKLHLAENAEPEEQSAA 200


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 36.2 bits (82), Expect = 0.032
 Identities = 21/66 (31%), Positives = 37/66 (56%), Gaps = 7/66 (10%)

Query: 202 SIEQMEHVRGMQEKLARLNLELYGELEELPED-------KRKTASDSNLDRLLSDLEELN 254
           ++E  EH+R  +E+L+R+  EL   L +           K + A   NL + LS+LE+LN
Sbjct: 606 NLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLN 665

Query: 255 SSIQKL 260
            +++K+
Sbjct: 666 ENLKKV 671


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 33.1 bits (74), Expect = 0.27
 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 85  NKELKTMEER-KVKRRSPKSFSAHCTQVVNAKKNAIPVSKSTGFSNPASQSTSQRPKLKR 143
           +KE    EER K+K+ S KSF     + +  ++  IP  K + F++    +  +   L  
Sbjct: 719 SKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHL 778

Query: 144 VMKE-KTKPQGGEGKGAQSTPIQHSFLTDVSDVQEMER 180
           V KE   + Q    K ++  P + S + +  D+++MER
Sbjct: 779 VEKEIDIEKQEKHIKESKEKPEKRSQIKE-KDIEKMER 815


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 33.1 bits (74), Expect = 0.27
 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 85  NKELKTMEER-KVKRRSPKSFSAHCTQVVNAKKNAIPVSKSTGFSNPASQSTSQRPKLKR 143
           +KE    EER K+K+ S KSF     + +  ++  IP  K + F++    +  +   L  
Sbjct: 742 SKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHL 801

Query: 144 VMKE-KTKPQGGEGKGAQSTPIQHSFLTDVSDVQEMER 180
           V KE   + Q    K ++  P + S + +  D+++MER
Sbjct: 802 VEKEIDIEKQEKHIKESKEKPEKRSQIKE-KDIEKMER 838


>gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]
          Length = 855

 Score = 32.7 bits (73), Expect = 0.35
 Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 9/110 (8%)

Query: 142 KRVMKEKTKPQGGEGKGAQSTPIQHSFLTD--VSDVQEMERGLLSLLNDFHSGKLQAFGN 199
           K  +  KT     EG    S  +    L++  +S++Q++++ L+ +  +  +G L    +
Sbjct: 310 KLPLDNKTSTPKKEGLAPPSPSLVSDLLSELNISEIQKLKQQLMQMERE-KAGLLATLQD 368

Query: 200 ECSIEQMEHVRG----MQEKLARLNLELYGELEELPEDKRKTASDSNLDR 245
             + +Q+EH RG     QEK+ RL   L          +R+TA D+  DR
Sbjct: 369 --TQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDR 416


>gi|20544168 histone cluster 1, H1t [Homo sapiens]
          Length = 207

 Score = 32.7 bits (73), Expect = 0.35
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 7/74 (9%)

Query: 97  KRRSPKSFSAHCTQVVNAKKNAIPVSKSTGFSNPASQSTSQRPKLKRVMKEKT-----KP 151
           K+  PKS  +   + V+AK   + +S+ +   +P +  T++R K  R    KT     K 
Sbjct: 113 KKVIPKSTRSKAKKSVSAKTKKLVLSRDS--KSPKTAKTNKRAKKPRATTPKTVRSGRKA 170

Query: 152 QGGEGKGAQSTPIQ 165
           +G +GK  Q +P++
Sbjct: 171 KGAKGKQQQKSPVK 184


>gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]
          Length = 824

 Score = 32.7 bits (73), Expect = 0.35
 Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 9/110 (8%)

Query: 142 KRVMKEKTKPQGGEGKGAQSTPIQHSFLTD--VSDVQEMERGLLSLLNDFHSGKLQAFGN 199
           K  +  KT     EG    S  +    L++  +S++Q++++ L+ +  +  +G L    +
Sbjct: 310 KLPLDNKTSTPKKEGLAPPSPSLVSDLLSELNISEIQKLKQQLMQMERE-KAGLLATLQD 368

Query: 200 ECSIEQMEHVRG----MQEKLARLNLELYGELEELPEDKRKTASDSNLDR 245
             + +Q+EH RG     QEK+ RL   L          +R+TA D+  DR
Sbjct: 369 --TQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDR 416


>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
            [Homo sapiens]
          Length = 1388

 Score = 32.0 bits (71), Expect = 0.60
 Identities = 41/191 (21%), Positives = 76/191 (39%), Gaps = 23/191 (12%)

Query: 92   EERKVKRRSPKSFSAHCTQVVNAKKNAIPVSKSTG------FSNPASQSTSQRPKLKRVM 145
            +E+ +K    K   A   Q +  K   I   + T        +N A++      KLK V 
Sbjct: 941  KEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQ 1000

Query: 146  KEKTKPQGGE-GKGAQSTPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIE 204
            ++ ++ +  E    A     +   LT+ +   +    L  ++N     K    GN+  + 
Sbjct: 1001 EQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKR---GNDTDVR 1057

Query: 205  QME--------HVRGMQEKLARLNLELYGELEELP-----EDKRKTASDSNLDRLLSDLE 251
            + E         ++  +EKL +  ++   EL E+      E + +      LD   SD+E
Sbjct: 1058 RKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIE 1117

Query: 252  ELNSSIQKLHL 262
            +L S +Q LH+
Sbjct: 1118 QLRSQLQALHI 1128


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 32.0 bits (71), Expect = 0.60
 Identities = 27/132 (20%), Positives = 55/132 (41%), Gaps = 1/132 (0%)

Query: 135  TSQRPKLKRVMKEKTKPQGGEGKGAQSTPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKL 194
            T Q  +LKR M+E+TK +       QS+      L +  + ++  +  L       + ++
Sbjct: 1313 TQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEV 1372

Query: 195  QAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKTAS-DSNLDRLLSDLEEL 253
              +  +   + ++    ++E   +L   L    E       K AS +    RL  ++E+L
Sbjct: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDL 1432

Query: 254  NSSIQKLHLADA 265
               +++ H A A
Sbjct: 1433 MRDLERSHTACA 1444


>gi|56550043 sarcolemma associated protein [Homo sapiens]
          Length = 811

 Score = 32.0 bits (71), Expect = 0.60
 Identities = 49/254 (19%), Positives = 100/254 (39%), Gaps = 22/254 (8%)

Query: 30  HFRKQTELRRSGSRDVTGALLVAAAVASEAVGSLRVAEGGPNTLLLQVLRSWPWCNKELK 89
           H ++  E  +   R++      A     +    L+VAEG    +  +          ++ 
Sbjct: 288 HLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKID 347

Query: 90  TMEERKVKRRSPKSFSAHCTQVVNAKKNAIP---VSKSTGFSNPASQSTSQRPKL----- 141
            MEE++ + ++            N +  A+    +SKS G      Q    + KL     
Sbjct: 348 EMEEKEQELQAKIEALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGH 407

Query: 142 -KRVMKEKTKPQGGEGKGAQS------TPIQHSFLTDVSDVQEMERGL------LSLLND 188
             + ++E    +  + +  +S      +P +     D +D Q  E+ L      +SLL D
Sbjct: 408 LTKAVEETKLSKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKD 467

Query: 189 FHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKTASDSNLDRLLS 248
              G       +  I+ +       ++LAR + +   EL+ L E++RK A  + ++    
Sbjct: 468 DLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERK-AYRNQVEESTK 526

Query: 249 DLEELNSSIQKLHL 262
            ++ L + +Q+LH+
Sbjct: 527 QIQVLQAQLQRLHI 540


>gi|27881501 ATP-binding cassette, sub-family A, member 12 isoform b
           [Homo sapiens]
          Length = 2277

 Score = 31.6 bits (70), Expect = 0.78
 Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 11/72 (15%)

Query: 203 IEQMEHVRGM---QEKLARLNLELYGELEELPEDKRKTASDSN--LDRLLS-----DLEE 252
           IE M HV       EK  +L LE++  +EEL ED R+T   SN  +D+LL+     +  E
Sbjct: 218 IEAMLHVNNSADASEKPGQL-LEMFKNVEELKEDLRRTTGMSNRTIDKLLAIPIPDNRAE 276

Query: 253 LNSSIQKLHLAD 264
           + S +  LH  D
Sbjct: 277 IISQVFWLHSCD 288


>gi|30795238 ATP-binding cassette, sub-family A, member 12 isoform a
           [Homo sapiens]
          Length = 2595

 Score = 31.6 bits (70), Expect = 0.78
 Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 11/72 (15%)

Query: 203 IEQMEHVRGM---QEKLARLNLELYGELEELPEDKRKTASDSN--LDRLLS-----DLEE 252
           IE M HV       EK  +L LE++  +EEL ED R+T   SN  +D+LL+     +  E
Sbjct: 536 IEAMLHVNNSADASEKPGQL-LEMFKNVEELKEDLRRTTGMSNRTIDKLLAIPIPDNRAE 594

Query: 253 LNSSIQKLHLAD 264
           + S +  LH  D
Sbjct: 595 IISQVFWLHSCD 606


>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
          Length = 968

 Score = 31.2 bits (69), Expect = 1.0
 Identities = 15/77 (19%), Positives = 37/77 (48%)

Query: 168 FLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGEL 227
           F T++ +++  ++  +  +   H+ + +       +EQ       QE+L  +  E+  E+
Sbjct: 609 FDTELENLERQQKQQVEKMEQDHAVRRREEARRIRLEQDRDYTRFQEQLKLMKKEVKNEV 668

Query: 228 EELPEDKRKTASDSNLD 244
           E+LP  +RK +    ++
Sbjct: 669 EKLPRQQRKESMKQKME 685


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
          Length = 1293

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 38/184 (20%), Positives = 67/184 (36%), Gaps = 36/184 (19%)

Query: 69   GPNTLLLQVLRSWPWCNKELKTME----ERKVKRRSPKSFSAHCTQVVNAKKNAIPVSKS 124
            GP       L S  W N + K       +  VK   P++ +       N  KN   +SKS
Sbjct: 1046 GPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNST-------NKNKNNASLSKS 1098

Query: 125  TGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQ------------STPIQHSFLTDV 172
             G SN  ++   +  KL ++ +   K Q G  +  +              P   SFL +V
Sbjct: 1099 VGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEV 1158

Query: 173  SDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPE 232
                E+   + + L D             + E  E  +   E+ A+       + ++LP+
Sbjct: 1159 ESPYEVHDYIRAYLGD-------------TSEAKEFAKQFLERRAKQKANQQRQQQQLPQ 1205

Query: 233  DKRK 236
             +++
Sbjct: 1206 QQQQ 1209


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
          Length = 1320

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 38/184 (20%), Positives = 67/184 (36%), Gaps = 36/184 (19%)

Query: 69   GPNTLLLQVLRSWPWCNKELKTME----ERKVKRRSPKSFSAHCTQVVNAKKNAIPVSKS 124
            GP       L S  W N + K       +  VK   P++ +       N  KN   +SKS
Sbjct: 1073 GPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNST-------NKNKNNASLSKS 1125

Query: 125  TGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQ------------STPIQHSFLTDV 172
             G SN  ++   +  KL ++ +   K Q G  +  +              P   SFL +V
Sbjct: 1126 VGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEV 1185

Query: 173  SDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPE 232
                E+   + + L D             + E  E  +   E+ A+       + ++LP+
Sbjct: 1186 ESPYEVHDYIRAYLGD-------------TSEAKEFAKQFLERRAKQKANQQRQQQQLPQ 1232

Query: 233  DKRK 236
             +++
Sbjct: 1233 QQQQ 1236


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
          Length = 1299

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 38/184 (20%), Positives = 67/184 (36%), Gaps = 36/184 (19%)

Query: 69   GPNTLLLQVLRSWPWCNKELKTME----ERKVKRRSPKSFSAHCTQVVNAKKNAIPVSKS 124
            GP       L S  W N + K       +  VK   P++ +       N  KN   +SKS
Sbjct: 1052 GPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNST-------NKNKNNASLSKS 1104

Query: 125  TGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQ------------STPIQHSFLTDV 172
             G SN  ++   +  KL ++ +   K Q G  +  +              P   SFL +V
Sbjct: 1105 VGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEV 1164

Query: 173  SDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPE 232
                E+   + + L D             + E  E  +   E+ A+       + ++LP+
Sbjct: 1165 ESPYEVHDYIRAYLGD-------------TSEAKEFAKQFLERRAKQKANQQRQQQQLPQ 1211

Query: 233  DKRK 236
             +++
Sbjct: 1212 QQQQ 1215


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
          Length = 1299

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 38/184 (20%), Positives = 67/184 (36%), Gaps = 36/184 (19%)

Query: 69   GPNTLLLQVLRSWPWCNKELKTME----ERKVKRRSPKSFSAHCTQVVNAKKNAIPVSKS 124
            GP       L S  W N + K       +  VK   P++ +       N  KN   +SKS
Sbjct: 1052 GPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNST-------NKNKNNASLSKS 1104

Query: 125  TGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQ------------STPIQHSFLTDV 172
             G SN  ++   +  KL ++ +   K Q G  +  +              P   SFL +V
Sbjct: 1105 VGVSNRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEV 1164

Query: 173  SDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPE 232
                E+   + + L D             + E  E  +   E+ A+       + ++LP+
Sbjct: 1165 ESPYEVHDYIRAYLGD-------------TSEAKEFAKQFLERRAKQKANQQRQQQQLPQ 1211

Query: 233  DKRK 236
             +++
Sbjct: 1212 QQQQ 1215


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 24/100 (24%), Positives = 51/100 (51%), Gaps = 3/100 (3%)

Query: 160  QSTPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIE-QMEHVRGMQEKLAR 218
            Q   ++    T  S+V++ +  + SL    +  K        +IE +++     Q +L +
Sbjct: 947  QVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEK 1006

Query: 219  LNLELYGELEELPEDKRKTASDSNLDRLLSDLEELNSSIQ 258
              +E+  E +EL +DKR+     ++++ LS+L++  SS+Q
Sbjct: 1007 KLMEVEKEKQELQDDKRRAI--ESMEQQLSELKKTLSSVQ 1044


>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
          Length = 326

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 14/71 (19%)

Query: 199 NECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKTASDSNLDRLLS-----DLEEL 253
           + C+  +M  V+GMQEK         GEL+EL +      S S   R  +      LEEL
Sbjct: 97  DNCNSLRMSPVKGMQEK---------GELDELGDKCDSNVSSSKKRRHRTTFTSLQLEEL 147

Query: 254 NSSIQKLHLAD 264
               QK H  D
Sbjct: 148 EKVFQKTHYPD 158


>gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]
          Length = 1580

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 16/55 (29%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 119  IPVSKSTGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQSTPIQHSFLTDVS 173
            +P   S    NP + +TS   K   V++  T+P+GG+ +   S+P   S   +V+
Sbjct: 1021 VPRFSSLSSCNPPAMATSAE-KRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVT 1074


>gi|10835073 N-myristoyltransferase 1 [Homo sapiens]
          Length = 496

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 8/76 (10%)

Query: 107 HCTQVVNAKKNAIPVSKSTGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQSTPIQH 166
           HC+   N + N    S + G  +PA+ + +++ K K+   +K K +G E   AQ  P++ 
Sbjct: 29  HCSDCENEEDN----SYNRGGLSPANDTGAKKKKKKQ---KKKKEKGSETDSAQDQPVKM 81

Query: 167 SFLTDVSDVQEMERGL 182
           + L     +QE+++ +
Sbjct: 82  NSL-PAERIQEIQKAI 96


>gi|56119214 GTPase, IMAP family member 6 [Homo sapiens]
          Length = 292

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 16/51 (31%), Positives = 29/51 (56%), Gaps = 4/51 (7%)

Query: 127 FSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQSTPIQHSFLTDVSDVQE 177
           +SN A Q T Q  +LK + +     Q  +G+G++  P + S+L  +S +Q+
Sbjct: 231 YSNKAYQYTQQNFRLKELQER----QVSQGQGSEDVPGEESWLEGLSQIQK 277


>gi|18087819 hypothetical protein LOC91283 [Homo sapiens]
          Length = 275

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 22/107 (20%), Positives = 42/107 (39%), Gaps = 9/107 (8%)

Query: 102 KSFSAHCTQVVNAKKNAIPVSKSTGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQS 161
           +SF+    ++ + +K  I      G S P    ++ R    +  + KT  +G   K  + 
Sbjct: 140 ESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEE 199

Query: 162 TPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEH 208
              Q   +  +  +Q         +N+ H  K+Q    EC + + EH
Sbjct: 200 EHHQQMSILQLQLIQ---------MNEVHVAKIQQIERECEMAEEEH 237


>gi|111038124 succinate dehydrogenase complex assembly factor 1
          [Homo sapiens]
          Length = 115

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 2/62 (3%)

Query: 2  PRAEPRATLGEQEKAGLPLG-AWRL-YLLRHFRKQTELRRSGSRDVTGALLVAAAVASEA 59
          P AE R     ++ AGLP     R+ YL R  R+Q +L RSG     GA +   A   E 
Sbjct: 26 PGAEARVRAEFRQHAGLPRSDVLRIEYLYRRGRRQLQLLRSGHATAMGAFVRPRAPTGEP 85

Query: 60 VG 61
           G
Sbjct: 86 GG 87


>gi|165905591 LIM domain and actin binding 1 isoform c [Homo
           sapiens]
          Length = 600

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 32/141 (22%), Positives = 56/141 (39%), Gaps = 14/141 (9%)

Query: 11  GEQEKAGLPLGAWRLYLLRHFRKQTELRRSGSRDVTGALLVAAAVASEAVGSLRVAEGGP 70
           G+ EK  +PL   ++   +    QT++ R+ SR  +G  +   +  S ++  L +  G  
Sbjct: 25  GKIEKYNVPLNRLKMMFEKGEPTQTKILRAQSRSASGRKI---SENSYSLDDLEIGPGQL 81

Query: 71  NTLLLQVLRSWPWCNKELKTMEERKVKRRSPKSFSAHCTQVVNAKKNAIPVSKSTGFSNP 130
           ++      ++    N EL  + E  +K R  K  +A   Q           S ST ++N 
Sbjct: 82  SSSTFDSEKNESRRNLELPRLSETSIKDRMAKYQAAVSKQ-----------SSSTNYTNE 130

Query: 131 ASQSTSQRPKLKRVMKEKTKP 151
              S  +    K   KE   P
Sbjct: 131 LKASGGEIKIHKMEQKENVPP 151


>gi|165905589 LIM domain and actin binding 1 isoform a [Homo
           sapiens]
          Length = 760

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 32/141 (22%), Positives = 56/141 (39%), Gaps = 14/141 (9%)

Query: 11  GEQEKAGLPLGAWRLYLLRHFRKQTELRRSGSRDVTGALLVAAAVASEAVGSLRVAEGGP 70
           G+ EK  +PL   ++   +    QT++ R+ SR  +G  +   +  S ++  L +  G  
Sbjct: 185 GKIEKYNVPLNRLKMMFEKGEPTQTKILRAQSRSASGRKI---SENSYSLDDLEIGPGQL 241

Query: 71  NTLLLQVLRSWPWCNKELKTMEERKVKRRSPKSFSAHCTQVVNAKKNAIPVSKSTGFSNP 130
           ++      ++    N EL  + E  +K R  K  +A   Q           S ST ++N 
Sbjct: 242 SSSTFDSEKNESRRNLELPRLSETSIKDRMAKYQAAVSKQ-----------SSSTNYTNE 290

Query: 131 ASQSTSQRPKLKRVMKEKTKP 151
              S  +    K   KE   P
Sbjct: 291 LKASGGEIKIHKMEQKENVPP 311


>gi|7705373 LIM domain and actin binding 1 isoform b [Homo sapiens]
          Length = 759

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 32/141 (22%), Positives = 56/141 (39%), Gaps = 14/141 (9%)

Query: 11  GEQEKAGLPLGAWRLYLLRHFRKQTELRRSGSRDVTGALLVAAAVASEAVGSLRVAEGGP 70
           G+ EK  +PL   ++   +    QT++ R+ SR  +G  +   +  S ++  L +  G  
Sbjct: 185 GKIEKYNVPLNRLKMMFEKGEPTQTKILRAQSRSASGRKI---SENSYSLDDLEIGPGQL 241

Query: 71  NTLLLQVLRSWPWCNKELKTMEERKVKRRSPKSFSAHCTQVVNAKKNAIPVSKSTGFSNP 130
           ++      ++    N EL  + E  +K R  K  +A   Q           S ST ++N 
Sbjct: 242 SSSTFDSEKNESRRNLELPRLSETSIKDRMAKYQAAVSKQ-----------SSSTNYTNE 290

Query: 131 ASQSTSQRPKLKRVMKEKTKP 151
              S  +    K   KE   P
Sbjct: 291 LKASGGEIKIHKMEQKENVPP 311


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 41/212 (19%), Positives = 82/212 (38%), Gaps = 19/212 (8%)

Query: 58   EAVGSLRVAEGGPNTLLLQVLRSWPWCNKELKTM----EERKVKRRSPKSFSAHCTQVVN 113
            E V      E   NT L+ + +      K+L+ M    +E+ + R   +       Q + 
Sbjct: 2032 EQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLE 2091

Query: 114  AKKNAIPVSKSTGFSNPASQSTSQRPKLKRVMKEKTKPQGGEGKGAQSTPIQHSFLTDVS 173
             +   +P      F   +   T +  +L   +KEKT       K ++    +     D+ 
Sbjct: 2092 QQLKVVP-----RFQPISEHQTREVEQLANHLKEKTD------KCSELLLSKEQLQRDIQ 2140

Query: 174  DVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPED 233
            +  E    L   + +     L +      +E  +H   ++ K   L+LE+  + E    D
Sbjct: 2141 ERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAK-PELSLEVQLQAERDAID 2199

Query: 234  KRK---TASDSNLDRLLSDLEELNSSIQKLHL 262
            +++   T  +  L++   +LE  N  +Q+LH+
Sbjct: 2200 RKEKEITNLEEQLEQFREELENKNEEVQQLHM 2231


>gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo
           sapiens]
          Length = 1151

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 16/49 (32%), Positives = 27/49 (55%)

Query: 225 GELEELPEDKRKTASDSNLDRLLSDLEELNSSIQKLHLADAQDVPNTSA 273
           G+   LP + RKT  D +L    ++LE     ++ L+ A + +VP +SA
Sbjct: 612 GDCSILPREDRKTNLDKDLSLCQTELEADLEKMETLNKAPSANVPQSSA 660


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.127    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,147,159
Number of Sequences: 37866
Number of extensions: 446913
Number of successful extensions: 1534
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 60
Number of HSP's that attempted gapping in prelim test: 1507
Number of HSP's gapped (non-prelim): 87
length of query: 274
length of database: 18,247,518
effective HSP length: 101
effective length of query: 173
effective length of database: 14,423,052
effective search space: 2495187996
effective search space used: 2495187996
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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