Guide to the Human Genome
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Search of human proteins with 26787993

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|26787993 stonin 1 [Homo sapiens]
         (735 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|26787993 stonin 1 [Homo sapiens]                                  1513   0.0  
gi|29553944 STON1-GTF2A1L protein [Homo sapiens]                     1464   0.0  
gi|21361863 stonin 2 [Homo sapiens]                                   406   e-113
gi|14210504 adaptor-related protein complex 1, mu 1 subunit isof...    73   8e-13
gi|194473724 adaptor-related protein complex 1, mu 1 subunit iso...    70   9e-12
gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo...    63   9e-10
gi|68799814 adaptor-related protein complex 2, mu 1 subunit isof...    61   4e-09
gi|14917109 adaptor-related protein complex 2, mu 1 subunit isof...    61   4e-09
gi|54860079 nadrin isoform 1 [Homo sapiens]                            45   2e-04
gi|54860105 nadrin isoform 2 [Homo sapiens]                            45   2e-04
gi|223468617 family with sequence similarity 75, member C1 [Homo...    40   0.006
gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Hom...    40   0.006
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         39   0.023
gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens]    37   0.050
gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens]    37   0.050
gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens]    37   0.050
gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens]     37   0.050
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    37   0.066
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  37   0.066
gi|38787970 tensin like C1 domain containing phosphatase isoform...    37   0.066
gi|38787957 tensin like C1 domain containing phosphatase isoform...    37   0.066
gi|38787941 tensin like C1 domain containing phosphatase isoform...    37   0.066
gi|16418357 ankyrin repeat domain 40 [Homo sapiens]                    37   0.066
gi|148536848 carboxyl ester lipase precursor [Homo sapiens]            37   0.086
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]            36   0.11 
gi|31543452 PX domain containing serine/threonine kinase [Homo s...    36   0.15 
gi|116292174 fidgetin-like 2 [Homo sapiens]                            35   0.19 
gi|29294655 melanoma antigen family C, 3 isoform 2 [Homo sapiens]      35   0.19 
gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]    35   0.25 
gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]    35   0.25 

>gi|26787993 stonin 1 [Homo sapiens]
          Length = 735

 Score = 1513 bits (3918), Expect = 0.0
 Identities = 735/735 (100%), Positives = 735/735 (100%)

Query: 1   MCSTNPGKWVTFDDDPAVQSSQKSKNFPLENQGVCRPNGLKLNLPGLREFPSGSSSTSST 60
           MCSTNPGKWVTFDDDPAVQSSQKSKNFPLENQGVCRPNGLKLNLPGLREFPSGSSSTSST
Sbjct: 1   MCSTNPGKWVTFDDDPAVQSSQKSKNFPLENQGVCRPNGLKLNLPGLREFPSGSSSTSST 60

Query: 61  PLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDSPLAISGGE 120
           PLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDSPLAISGGE
Sbjct: 61  PLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDSPLAISGGE 120

Query: 121 SSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQSDDLPQFQYFREDC 180
           SSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQSDDLPQFQYFREDC
Sbjct: 121 SSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQSDDLPQFQYFREDC 180

Query: 181 AFSSPFWKDEGSDSHFTLDPPGSKKMFSSRNKEMPIDQKSLNKCSLNYICEKLEHLQSAE 240
           AFSSPFWKDEGSDSHFTLDPPGSKKMFSSRNKEMPIDQKSLNKCSLNYICEKLEHLQSAE
Sbjct: 181 AFSSPFWKDEGSDSHFTLDPPGSKKMFSSRNKEMPIDQKSLNKCSLNYICEKLEHLQSAE 240

Query: 241 NQDSLRSLSMHCLCAEENASSFVPHTLFRSQPKSGWSFMLRIPEKKNMMSSRQWGPIFLK 300
           NQDSLRSLSMHCLCAEENASSFVPHTLFRSQPKSGWSFMLRIPEKKNMMSSRQWGPIFLK
Sbjct: 241 NQDSLRSLSMHCLCAEENASSFVPHTLFRSQPKSGWSFMLRIPEKKNMMSSRQWGPIFLK 300

Query: 301 VLPGGILQMYYEQGLEKPFKEIQLDPYCRLSEPKVENFSVAGKIHTVKIEHVSYTEKRKY 360
           VLPGGILQMYYEQGLEKPFKEIQLDPYCRLSEPKVENFSVAGKIHTVKIEHVSYTEKRKY
Sbjct: 301 VLPGGILQMYYEQGLEKPFKEIQLDPYCRLSEPKVENFSVAGKIHTVKIEHVSYTEKRKY 360

Query: 361 HSKTEVVHEPDIEQMLKLGSTSYHDFLDFLTTVEEELMKLPAVSKPKKNYEEQEISLEIV 420
           HSKTEVVHEPDIEQMLKLGSTSYHDFLDFLTTVEEELMKLPAVSKPKKNYEEQEISLEIV
Sbjct: 361 HSKTEVVHEPDIEQMLKLGSTSYHDFLDFLTTVEEELMKLPAVSKPKKNYEEQEISLEIV 420

Query: 421 DNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLNDLELPKRDESYYEKDSEKKGI 480
           DNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLNDLELPKRDESYYEKDSEKKGI
Sbjct: 421 DNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLNDLELPKRDESYYEKDSEKKGI 480

Query: 481 DILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFKTLYNGDNLPFSLKSVVVVQGAY 540
           DILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFKTLYNGDNLPFSLKSVVVVQGAY
Sbjct: 481 DILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFKTLYNGDNLPFSLKSVVVVQGAY 540

Query: 541 VELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQWIKALWTMNLQRQKSLKAKMNRR 600
           VELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQWIKALWTMNLQRQKSLKAKMNRR
Sbjct: 541 VELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQWIKALWTMNLQRQKSLKAKMNRR 600

Query: 601 ACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSLDHPHCLSYKLELGSD 660
           ACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSLDHPHCLSYKLELGSD
Sbjct: 601 ACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSLDHPHCLSYKLELGSD 660

Query: 661 QEIPSDWYPFATVQFSVPDTCASRTEVRSLGVESDVQPQKHVQQRACYNIQVEIEKKWIK 720
           QEIPSDWYPFATVQFSVPDTCASRTEVRSLGVESDVQPQKHVQQRACYNIQVEIEKKWIK
Sbjct: 661 QEIPSDWYPFATVQFSVPDTCASRTEVRSLGVESDVQPQKHVQQRACYNIQVEIEKKWIK 720

Query: 721 IDGEDPDKIGDCITQ 735
           IDGEDPDKIGDCITQ
Sbjct: 721 IDGEDPDKIGDCITQ 735


>gi|29553944 STON1-GTF2A1L protein [Homo sapiens]
          Length = 1182

 Score = 1464 bits (3789), Expect = 0.0
 Identities = 712/720 (98%), Positives = 716/720 (99%)

Query: 1   MCSTNPGKWVTFDDDPAVQSSQKSKNFPLENQGVCRPNGLKLNLPGLREFPSGSSSTSST 60
           MCSTNPGKWVTFDDDPAVQSSQKSKNFPLENQGVCRPNGLKLNLPGLREFPSGSSSTSST
Sbjct: 1   MCSTNPGKWVTFDDDPAVQSSQKSKNFPLENQGVCRPNGLKLNLPGLREFPSGSSSTSST 60

Query: 61  PLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDSPLAISGGE 120
           PLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDSPLAISGGE
Sbjct: 61  PLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDSPLAISGGE 120

Query: 121 SSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQSDDLPQFQYFREDC 180
           SSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQSDDLPQFQYFREDC
Sbjct: 121 SSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQSDDLPQFQYFREDC 180

Query: 181 AFSSPFWKDEGSDSHFTLDPPGSKKMFSSRNKEMPIDQKSLNKCSLNYICEKLEHLQSAE 240
           AFSSPFWKDEGSDSHFTLDPPGSKKMFSSRNKEMPIDQKSLNKCSLNYICEKLEHLQSAE
Sbjct: 181 AFSSPFWKDEGSDSHFTLDPPGSKKMFSSRNKEMPIDQKSLNKCSLNYICEKLEHLQSAE 240

Query: 241 NQDSLRSLSMHCLCAEENASSFVPHTLFRSQPKSGWSFMLRIPEKKNMMSSRQWGPIFLK 300
           NQDSLRSLSMHCLCAEENASSFVPHTLFRSQPKSGWSFMLRIPEKKNMMSSRQWGPIFLK
Sbjct: 241 NQDSLRSLSMHCLCAEENASSFVPHTLFRSQPKSGWSFMLRIPEKKNMMSSRQWGPIFLK 300

Query: 301 VLPGGILQMYYEQGLEKPFKEIQLDPYCRLSEPKVENFSVAGKIHTVKIEHVSYTEKRKY 360
           VLPGGILQMYYEQGLEKPFKEIQLDPYCRLSEPKVENFSVAGKIHTVKIEHVSYTEKRKY
Sbjct: 301 VLPGGILQMYYEQGLEKPFKEIQLDPYCRLSEPKVENFSVAGKIHTVKIEHVSYTEKRKY 360

Query: 361 HSKTEVVHEPDIEQMLKLGSTSYHDFLDFLTTVEEELMKLPAVSKPKKNYEEQEISLEIV 420
           HSKTEVVHEPDIEQMLKLGSTSYHDFLDFLTTVEEELMKLPAVSKPKKNYEEQEISLEIV
Sbjct: 361 HSKTEVVHEPDIEQMLKLGSTSYHDFLDFLTTVEEELMKLPAVSKPKKNYEEQEISLEIV 420

Query: 421 DNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLNDLELPKRDESYYEKDSEKKGI 480
           DNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLNDLELPKRDESYYEKDSEKKGI
Sbjct: 421 DNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLNDLELPKRDESYYEKDSEKKGI 480

Query: 481 DILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFKTLYNGDNLPFSLKSVVVVQGAY 540
           DILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFKTLYNGDNLPFSLKSVVVVQGAY
Sbjct: 481 DILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFKTLYNGDNLPFSLKSVVVVQGAY 540

Query: 541 VELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQWIKALWTMNLQRQKSLKAKMNRR 600
           VELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQWIKALWTMNLQRQKSLKAKMNRR
Sbjct: 541 VELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQWIKALWTMNLQRQKSLKAKMNRR 600

Query: 601 ACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSLDHPHCLSYKLELGSD 660
           ACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSLDHPHCLSYKLELGSD
Sbjct: 601 ACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSLDHPHCLSYKLELGSD 660

Query: 661 QEIPSDWYPFATVQFSVPDTCASRTEVRSLGVESDVQPQKHVQQRACYNIQVEIEKKWIK 720
           QEIPSDWYPFATVQFSVPDTCASRTEVRSLGVESDVQPQKHVQQRACYNIQ ++ +  I+
Sbjct: 661 QEIPSDWYPFATVQFSVPDTCASRTEVRSLGVESDVQPQKHVQQRACYNIQPKLYRSVIE 720


>gi|21361863 stonin 2 [Homo sapiens]
          Length = 905

 Score =  406 bits (1044), Expect = e-113
 Identities = 209/462 (45%), Positives = 306/462 (66%), Gaps = 10/462 (2%)

Query: 269 RSQPKSGWSFMLRIPEKKNMMSSRQWGPIFLKVLPGGILQMYYEQGLEKPFKEIQLDPYC 328
           RSQP+ GW  MLRIPEKKN+MSSR WGPIF+K+   G LQ+YYEQGLEKPF+E +L+   
Sbjct: 421 RSQPRDGWPMMLRIPEKKNIMSSRHWGPIFVKLTDTGYLQLYYEQGLEKPFREFKLEICH 480

Query: 329 RLSEPKVENFSVAGKIHTVKIEHVSYTEKRKYHSKTEVVHEPDIEQMLKLGSTSYHDFLD 388
            +SEP+++N+   G+IH+++I+ V+Y EK+KY  K  V H  + EQ++KLG+T+Y DFL 
Sbjct: 481 EISEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHTAEREQVIKLGTTNYDDFLS 540

Query: 389 FLTTVEEELMKLPAVSKPKK----NYEEQEISLEIVDNFWGKVTK-EGKFVESAVITQIY 443
           F+  V++ LM LP +S        NY E+EI++++ D F G V+K + + ++  V+T+I+
Sbjct: 541 FIHAVQDRLMDLPVLSMDLSTVGLNYLEEEITVDVRDEFSGIVSKGDNQILQHHVLTRIH 600

Query: 444 CLCFVNGNLECFLTLNDLELPKRDESYYEKD----SEKKGIDILDYHFHKCVNVQEFEQS 499
            L F++G  EC L LND+ L K +E    +D    +  K I + +  FH CV+   F  S
Sbjct: 601 ILSFLSGLAECRLGLNDI-LVKGNEIVLRQDIMPTTTTKWIKLHECRFHGCVDEDVFHNS 659

Query: 500 RIIKFVPLDACRFELMRFKTLYNGDNLPFSLKSVVVVQGAYVELQAFVNMASLAQRSSYA 559
           R+I F PLDACRFELMRF+T++    LPF+L++   V GA VE+Q+++ M++    +   
Sbjct: 660 RVILFNPLDACRFELMRFRTVFAEKTLPFTLRTATSVNGAEVEVQSWLRMSTGFSANRDP 719

Query: 560 GSLRSCDNIRIHFPVPSQWIKALWTMNLQRQKSLKAKMNRRACLGSLQELESEPVIQVTV 619
            +   C+N+ I +PVPS+W+K     ++  +KSLKAK+NR A  GS     SEPV++VT+
Sbjct: 720 LTQVPCENVMIRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSTSVSGSEPVMRVTL 779

Query: 620 GSAKYESAYQAVVWKIDRLPDKNSSLDHPHCLSYKLELGSDQEIPSDWYPFATVQFSVPD 679
           G+AKYE A+ ++VW+I+RLPDKNS+  HPHC    LELGSD+E+PS +     V+FS+P 
Sbjct: 780 GTAKYEHAFNSIVWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANHVNVEFSMPT 839

Query: 680 TCASRTEVRSLGVESDVQPQKHVQQRACYNIQVEIEKKWIKI 721
           T AS+  VRS+ VE     +K V   A Y+ QV +   W+ +
Sbjct: 840 TSASKASVRSISVEDKTDVRKWVNYSAHYSYQVALGSIWLML 881



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 14/56 (25%)

Query: 3  STNPGKWVTFDDDPAVQSSQKSKNFPLENQGVCRPNGLKLNLPGLREFPSGSSSTS 58
          +T+  +WV+F+++P          FP  +QG     G + +LPGL   P  S S+S
Sbjct: 9  ATHQSEWVSFNEEPP---------FPAHSQG-----GTEEHLPGLSSSPDQSESSS 50


>gi|14210504 adaptor-related protein complex 1, mu 1 subunit isoform
           2 [Homo sapiens]
          Length = 423

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 67/283 (23%), Positives = 110/283 (38%), Gaps = 51/283 (18%)

Query: 410 YEEQEISLEIVDNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLNDLELPKRDES 469
           Y + E+ L+++++    V+  G  + S ++  I    F++G  E  L LND  L      
Sbjct: 166 YRKNEVFLDVIESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGR 225

Query: 470 YYEKDSEKKGIDILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFKTLYNGDNLPFS 529
                 + K +++ D  FH+CV +  FE  R I F+P D   FELM ++   N    P  
Sbjct: 226 -----GKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDG-EFELMSYR--LNTHVKPLI 277

Query: 530 LKSVVVVQGAYVELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQWIKALWTMNLQR 589
               V+ + ++  ++  +   S  +R S A      +N+ IH PVP+             
Sbjct: 278 WIESVIEKHSHSRIEYMIKAKSQFKRRSTA------NNVEIHIPVPND------------ 319

Query: 590 QKSLKAKMNRRACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSLDHPH 649
                                  P  + TVGS K+      +VW I   P     L   H
Sbjct: 320 --------------------ADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAH 359

Query: 650 CLSYKLELGSDQEIPSDWYPFATVQFSVPDTCASRTEVRSLGV 692
                  L S +    +  P  +V+F +P    S  +VR L +
Sbjct: 360 -----FGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKI 397


>gi|194473724 adaptor-related protein complex 1, mu 1 subunit
           isoform 1 [Homo sapiens]
          Length = 435

 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 70/295 (23%), Positives = 112/295 (37%), Gaps = 63/295 (21%)

Query: 410 YEEQEISLEIVD--NFWGK----------VTKEGKFVESAVITQIYCLCFVNGNLECFLT 457
           Y + E+ L++++  N  GK          V+  G  + S ++  I    F++G  E  L 
Sbjct: 166 YRKNEVFLDVIESVNLLGKYPGVGWLGHTVSANGNVLRSEIVGSIKMRVFLSGMPELRLG 225

Query: 458 LNDLELPKRDESYYEKDSEKKGIDILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRF 517
           LND  L            + K +++ D  FH+CV +  FE  R I F+P D   FELM +
Sbjct: 226 LNDKVLFDNTGR-----GKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDG-EFELMSY 279

Query: 518 KTLYNGDNLPFSLKSVVVVQGAYVELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQ 577
           +   N    P      V+ + ++  ++  +   S  +R S A      +N+ IH PVP+ 
Sbjct: 280 R--LNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTA------NNVEIHIPVPND 331

Query: 578 WIKALWTMNLQRQKSLKAKMNRRACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDR 637
                                              P  + TVGS K+      +VW I  
Sbjct: 332 --------------------------------ADSPKFKTTVGSVKWVPENSEIVWSIKS 359

Query: 638 LPDKNSSLDHPHCLSYKLELGSDQEIPSDWYPFATVQFSVPDTCASRTEVRSLGV 692
            P     L   H       L S +    +  P  +V+F +P    S  +VR L +
Sbjct: 360 FPGGKEYLMRAH-----FGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKI 409


>gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo
           sapiens]
          Length = 423

 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 65/286 (22%), Positives = 111/286 (38%), Gaps = 57/286 (19%)

Query: 410 YEEQEISLEIVDNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLND---LELPKR 466
           Y++ E+ ++++++    V   G  + S ++  I    F++G  E  L LND    EL  R
Sbjct: 166 YKKNEVFIDVIESVNLLVNANGSVLLSEIVGTIKLKVFLSGMPELRLGLNDRVLFELTGR 225

Query: 467 DESYYEKDSEKKGIDILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFKTLYNGDNL 526
                   S+ K +++ D  FH+CV +  F+  R I F+P D   FELM ++   +    
Sbjct: 226 --------SKNKSVELEDVKFHQCVRLSRFDNDRTISFIPPDG-DFELMSYR--LSTQVK 274

Query: 527 PFSLKSVVVVQGAYVELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQWIKALWTMN 586
           P      V+ + ++  ++  V      ++ S A      + + I  PVPS          
Sbjct: 275 PLIWIESVIEKFSHSRVEIMVKAKGQFKKQSVA------NGVEISVPVPSD--------- 319

Query: 587 LQRQKSLKAKMNRRACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSLD 646
                                     P  + +VGSAKY      V+W I   P     L 
Sbjct: 320 -----------------------ADSPRFKTSVGSAKYVPERNVVIWSIKSFPGGKEYLM 356

Query: 647 HPHCLSYKLELGSDQEIPSDWYPFATVQFSVPDTCASRTEVRSLGV 692
             H       L S ++   +  P   V+F +P    S  +VR + +
Sbjct: 357 RAH-----FGLPSVEKEEVEGRPPIGVKFEIPYFTVSGIQVRYMKI 397


>gi|68799814 adaptor-related protein complex 2, mu 1 subunit isoform
           b [Homo sapiens]
          Length = 433

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 65/273 (23%), Positives = 122/273 (44%), Gaps = 51/273 (18%)

Query: 410 YEEQEISLEIVDNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLND-LELPKRDE 468
           Y   E+ L+++++    ++ +G+ + + V  ++    +++G  EC   +ND + + K+ +
Sbjct: 166 YRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGK 225

Query: 469 SYYEKDSE--KKGIDILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFKTLYNGDNL 526
              ++ S+  K+ I I D  FH+CV + +F+  R I F+P D   FELMR++T      L
Sbjct: 226 GTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDG-EFELMRYRTT-KDIIL 283

Query: 527 PFSLKSVVVVQG-AYVELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQWIKALWTM 585
           PF +  +V   G   +E++  +       +S++  SL +   I +  P P      L T 
Sbjct: 284 PFRVIPLVREVGRTKLEVKVVI-------KSNFKPSLLA-QKIEVRIPTP------LNTS 329

Query: 586 NLQRQKSLKAKMNRRACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSL 645
            +Q                          +    G AKY+++  A+VWKI R+     S 
Sbjct: 330 GVQ--------------------------VICMKGKAKYKASENAIVWKIKRMAGMKESQ 363

Query: 646 DHPHCLSYKLELGSDQEIPSDWYPFATVQFSVP 678
                +S ++EL    +      P  ++ F VP
Sbjct: 364 -----ISAEIELLPTNDKKKWARPPISMNFEVP 391


>gi|14917109 adaptor-related protein complex 2, mu 1 subunit isoform
           a [Homo sapiens]
          Length = 435

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 65/273 (23%), Positives = 122/273 (44%), Gaps = 51/273 (18%)

Query: 410 YEEQEISLEIVDNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLND-LELPKRDE 468
           Y   E+ L+++++    ++ +G+ + + V  ++    +++G  EC   +ND + + K+ +
Sbjct: 168 YRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGK 227

Query: 469 SYYEKDSE--KKGIDILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMRFKTLYNGDNL 526
              ++ S+  K+ I I D  FH+CV + +F+  R I F+P D   FELMR++T      L
Sbjct: 228 GTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDG-EFELMRYRTT-KDIIL 285

Query: 527 PFSLKSVVVVQG-AYVELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVPSQWIKALWTM 585
           PF +  +V   G   +E++  +       +S++  SL +   I +  P P      L T 
Sbjct: 286 PFRVIPLVREVGRTKLEVKVVI-------KSNFKPSLLA-QKIEVRIPTP------LNTS 331

Query: 586 NLQRQKSLKAKMNRRACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSL 645
            +Q                          +    G AKY+++  A+VWKI R+     S 
Sbjct: 332 GVQ--------------------------VICMKGKAKYKASENAIVWKIKRMAGMKESQ 365

Query: 646 DHPHCLSYKLELGSDQEIPSDWYPFATVQFSVP 678
                +S ++EL    +      P  ++ F VP
Sbjct: 366 -----ISAEIELLPTNDKKKWARPPISMNFEVP 393


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 43/132 (32%), Positives = 53/132 (40%), Gaps = 22/132 (16%)

Query: 53  GSSSTSSTPLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDS 112
           G  S+S T    P +    SP PP+ SP S PT+     PG P A + +  P   SSS S
Sbjct: 652 GGQSSSGTSQHPPSL----SPKPPTRSP-SPPTQHTGQPPGQPSAPSQLSAPRRYSSSLS 706

Query: 113 PLAISGGESSLLPTRPTCLSHA-----------LLPSDHSCTHP--TPKVGLPDEVNPQQ 159
           P+          PT+ T L H             LPS+H    P  TP    P    P  
Sbjct: 707 PIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTP----PQTPTPPS 762

Query: 160 AESLGFQSDDLP 171
              LG Q+  LP
Sbjct: 763 TPPLGKQNPSLP 774


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 43/132 (32%), Positives = 53/132 (40%), Gaps = 22/132 (16%)

Query: 53  GSSSTSSTPLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDS 112
           G  S+S T    P +    SP PP+ SP S PT+     PG P A + +  P   SSS S
Sbjct: 574 GGQSSSGTSQHPPSL----SPKPPTRSP-SPPTQHTGQPPGQPSAPSQLSAPRRYSSSLS 628

Query: 113 PLAISGGESSLLPTRPTCLSHA-----------LLPSDHSCTHP--TPKVGLPDEVNPQQ 159
           P+          PT+ T L H             LPS+H    P  TP    P    P  
Sbjct: 629 PIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTP----PQTPTPPS 684

Query: 160 AESLGFQSDDLP 171
              LG Q+  LP
Sbjct: 685 TPPLGKQNPSLP 696


>gi|223468617 family with sequence similarity 75, member C1 [Homo
           sapiens]
          Length = 1188

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 44/150 (29%), Positives = 61/150 (40%), Gaps = 30/150 (20%)

Query: 51  PSGSSSTSSTPL--SSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPES 108
           P G+S +S  P+  ++PIV    SP P +  P    +   PG               P +
Sbjct: 143 PDGASRSSHEPMEDAAPIVSPLASPDPRTKHPQDLASTPPPG---------------PMT 187

Query: 109 SSDSPLAISGG-ESSLLPTRPTCLSHALLPSDH------SCTHPTPKVGLPDEVN----- 156
           +S S L+ S   E SLL  RP+    AL P         +C+ P PK   P  +      
Sbjct: 188 TSVSSLSASQPPEPSLLLERPSPEPPALFPHPPHTPDPLACSPPPPKGFTPPPLRDSTLL 247

Query: 157 -PQQAESLGFQSDDLPQFQYFREDCAFSSP 185
            P   +S+    D +PQ    RED A S P
Sbjct: 248 TPSHCDSVALPLDTVPQSLSPREDLAASVP 277


>gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Homo
           sapiens]
          Length = 453

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 44/197 (22%), Positives = 78/197 (39%), Gaps = 20/197 (10%)

Query: 401 PAVSKPKKNYEEQEISLEIVDNFWGKVTKEGKFVESAVITQIYCLCFVNGNLECFLTLND 460
           P +S      ++ E+ L++V+     +   G  ++  V  +I    F+    E  + L  
Sbjct: 173 PVLSSRSDQSQKNEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLT- 231

Query: 461 LELPKRDESYYEKDSEKKG----IDILDYHFHKCVNVQEFEQSRIIKFVPLDACRFELMR 516
                  E +    SE +G    I + +  FH  VN+ EFE  RI++  P       +MR
Sbjct: 232 -------EEFCVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQG-ELTVMR 283

Query: 517 FKTLYN-GDNLPFSLKSVVVVQGAYVELQAFVNMASLAQRSSYAGSLRSCDNIRIHFPVP 575
           ++   +    LPF L   V        LQ ++ +       S A       N+R+H P+P
Sbjct: 284 YQLSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQA------LNVRLHLPLP 337

Query: 576 SQWIKALWTMNLQRQKS 592
              +     ++   QK+
Sbjct: 338 RGVVSLSQELSSPEQKA 354


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 38.5 bits (88), Expect = 0.023
 Identities = 34/119 (28%), Positives = 49/119 (41%), Gaps = 18/119 (15%)

Query: 44  LPGLREFPSGSSSTSSTPLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLY 103
           L G +    G+ +  ST    P+    +SPGPPS +    PT   P   G P+       
Sbjct: 811 LEGQKYCYRGTGAAVSTR-PGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQ------- 862

Query: 104 PIPESSSDSPLAISGGESSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAES 162
             P +SS S  + SGG  +    R        +P   + T P P + LP    P ++ES
Sbjct: 863 --PSASSSSQFSTSGGPWA----RERRAGEEPVPGPMTPTQPPPPLSLP----PARSES 911


>gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens]
          Length = 1721

 Score = 37.4 bits (85), Expect = 0.050
 Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 8/116 (6%)

Query: 52  SGSSSTSSTPLSSPIVDFYFSP-GPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSS 110
           S S+S+     S+P   F  +  G P +S   +P + F   P IP   +++ YP PE  +
Sbjct: 609 SSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRS-PPIPYPRSYLPYPAPEGIA 667

Query: 111 DSPLAISGGESSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQ 166
            SPL++  G+  + P      + +L P      H  PK GLP  +   + E + +Q
Sbjct: 668 VSPLSLH-GKGPVYPHPVLLPNGSLFPG-----HLAPKPGLPYGLPTGRPEFVTYQ 717


>gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens]
          Length = 1755

 Score = 37.4 bits (85), Expect = 0.050
 Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 8/116 (6%)

Query: 52  SGSSSTSSTPLSSPIVDFYFSP-GPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSS 110
           S S+S+     S+P   F  +  G P +S   +P + F   P IP   +++ YP PE  +
Sbjct: 609 SSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRS-PPIPYPRSYLPYPAPEGIA 667

Query: 111 DSPLAISGGESSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQ 166
            SPL++  G+  + P      + +L P      H  PK GLP  +   + E + +Q
Sbjct: 668 VSPLSLH-GKGPVYPHPVLLPNGSLFPG-----HLAPKPGLPYGLPTGRPEFVTYQ 717


>gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens]
          Length = 1703

 Score = 37.4 bits (85), Expect = 0.050
 Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 8/116 (6%)

Query: 52  SGSSSTSSTPLSSPIVDFYFSP-GPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSS 110
           S S+S+     S+P   F  +  G P +S   +P + F   P IP   +++ YP PE  +
Sbjct: 609 SSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRS-PPIPYPRSYLPYPAPEGIA 667

Query: 111 DSPLAISGGESSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQ 166
            SPL++  G+  + P      + +L P      H  PK GLP  +   + E + +Q
Sbjct: 668 VSPLSLH-GKGPVYPHPVLLPNGSLFPG-----HLAPKPGLPYGLPTGRPEFVTYQ 717


>gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens]
          Length = 1721

 Score = 37.4 bits (85), Expect = 0.050
 Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 8/116 (6%)

Query: 52  SGSSSTSSTPLSSPIVDFYFSP-GPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSS 110
           S S+S+     S+P   F  +  G P +S   +P + F   P IP   +++ YP PE  +
Sbjct: 609 SSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRS-PPIPYPRSYLPYPAPEGIA 667

Query: 111 DSPLAISGGESSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQ 166
            SPL++  G+  + P      + +L P      H  PK GLP  +   + E + +Q
Sbjct: 668 VSPLSLH-GKGPVYPHPVLLPNGSLFPG-----HLAPKPGLPYGLPTGRPEFVTYQ 717


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 37.0 bits (84), Expect = 0.066
 Identities = 31/119 (26%), Positives = 48/119 (40%), Gaps = 23/119 (19%)

Query: 46   GLREFPSGSSSTSS--TPLSSPIVDFYFSPGPPSN--SPLSTPTKDFPGFPGIPKAGTHV 101
            G  E+P G+   S   +PL++PI++   SP P +N   P   P    P  PG P      
Sbjct: 955  GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASP 1014

Query: 102  LYPIPESSSDSPLAISGGESSLLPTRPTCLSHALLPSD---HSCTHPTPKVGLPDEVNP 157
            +   P     SPL                L H+L+P +     C+ P   + +P  ++P
Sbjct: 1015 ILMEPLPPQCSPL----------------LQHSLVPQNSPPSQCSPPALPLSVPSPLSP 1057



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 39/127 (30%), Positives = 51/127 (40%), Gaps = 13/127 (10%)

Query: 28  PLENQGVCRPNGLKLNLPGLREFPSGSSSTSSTPLSSPIVDFYFSPGPPSNSPLSTPTKD 87
           P E   +  P       P   E P  S     +PLS P      SP PP +SP+S P ++
Sbjct: 584 PPEESPMSPPPEASRLFPPFEESPL-SPPPEESPLSPPPEASRLSP-PPEDSPMSPPPEE 641

Query: 88  FPGFPGIPKAGTHVLYPIPESS------SDSPLAISGGESSLLPTRPTCLSHALLPSDHS 141
            P  P  P+     L P+P  S       +SPL+    ES   P  P   S    P + S
Sbjct: 642 SPMSPP-PEVSR--LSPLPVVSRLSPPPEESPLSPPPEESPTSP--PPEASRLSPPPEDS 696

Query: 142 CTHPTPK 148
            T P P+
Sbjct: 697 PTSPPPE 703



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 40/150 (26%), Positives = 55/150 (36%), Gaps = 22/150 (14%)

Query: 13  DDDPAVQSSQKSKNFPLENQGVCRPN------GLKLNLPGLREFPSGSSSTSSTPLSSPI 66
           ++ P     + S   PLE   +  P        L+  L    E    S     +PLS P 
Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP 558

Query: 67  VDFYFSPGP--------PSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDSPLAISG 118
            +   SP P        P  SP+S P ++ P  P  P   + +  P  E    SPL+   
Sbjct: 559 EELPTSPPPEASRLSPPPEESPMSPPPEESPMSP--PPEASRLFPPFEE----SPLSPPP 612

Query: 119 GESSLLPTRPTCLSHALLPSDHSCTHPTPK 148
            ES L P  P   S    P + S   P P+
Sbjct: 613 EESPLSP--PPEASRLSPPPEDSPMSPPPE 640



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 6/75 (8%)

Query: 58   SSTPLSSPIVDFYFSPGPPSNSPLSTPTKDFPGF---PGIPKAGTHVLYPIPESSSDSPL 114
            S TPL  P   F     P  N P S+P   +PG    P +        +       DSP 
Sbjct: 1917 SRTPLQRP---FLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPDSPW 1973

Query: 115  AISGGESSLLPTRPT 129
              SGG +   PT PT
Sbjct: 1974 TGSGGTTPSTPTTPT 1988



 Score = 30.4 bits (67), Expect = 6.1
 Identities = 31/99 (31%), Positives = 42/99 (42%), Gaps = 9/99 (9%)

Query: 51  PSGSSSTSSTP-LSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESS 109
           P G +     P L +P+ +      PP  SPLS P ++ P  P  P+A    L P PE  
Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP-PEASR--LSPPPEEL 474

Query: 110 SDSPLAISGGESSLLPTRPTCLSHALLPSDHSCTHPTPK 148
             SPL       +L  +RP   S    P + S   P P+
Sbjct: 475 PASPL-----PEALHLSRPLEESPLSPPPEESPLSPPPE 508


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 37.0 bits (84), Expect = 0.066
 Identities = 40/134 (29%), Positives = 53/134 (39%), Gaps = 17/134 (12%)

Query: 21   SQKSKNFPLENQGVCRPNGLKLNLPGLREFPSGSSSTSSTP-----------LSSPIVDF 69
            S +SKN    +Q   +P    +   GL    SGSSST   P           LS P +  
Sbjct: 1140 SSQSKN---SSQSGGKPGSSPITKHGLS---SGSSSTKMKPQGKPSSLMNPSLSKPNISP 1193

Query: 70   YFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDSPLAISGGESSLLPTRPT 129
              S  P  +  L++P K  PG P   KA + +      S      + SG +SS       
Sbjct: 1194 SHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSG 1253

Query: 130  CLSHALLPSDHSCT 143
             LS    PS +SCT
Sbjct: 1254 SLSQKTPPSSNSCT 1267


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
           [Homo sapiens]
          Length = 1285

 Score = 37.0 bits (84), Expect = 0.066
 Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 8/102 (7%)

Query: 48  REFPSGSSST---SSTPL--SSPIVDFYFSPGPPSNSPLSTPTKDF-PG--FPGIPKAGT 99
           R+ P  +SS     STPL  SSP+     +    + SP S PT+   PG   P + +AGT
Sbjct: 771 RDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGT 830

Query: 100 HVLYPIPESSSDSPLAISGGESSLLPTRPTCLSHALLPSDHS 141
                +P  S   PLA S    +  P+ P+       P  HS
Sbjct: 831 GKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHS 872


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
           [Homo sapiens]
          Length = 1409

 Score = 37.0 bits (84), Expect = 0.066
 Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 8/102 (7%)

Query: 48  REFPSGSSST---SSTPL--SSPIVDFYFSPGPPSNSPLSTPTKDF-PG--FPGIPKAGT 99
           R+ P  +SS     STPL  SSP+     +    + SP S PT+   PG   P + +AGT
Sbjct: 895 RDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGT 954

Query: 100 HVLYPIPESSSDSPLAISGGESSLLPTRPTCLSHALLPSDHS 141
                +P  S   PLA S    +  P+ P+       P  HS
Sbjct: 955 GKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHS 996


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
            [Homo sapiens]
          Length = 1419

 Score = 37.0 bits (84), Expect = 0.066
 Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 8/102 (7%)

Query: 48   REFPSGSSST---SSTPL--SSPIVDFYFSPGPPSNSPLSTPTKDF-PG--FPGIPKAGT 99
            R+ P  +SS     STPL  SSP+     +    + SP S PT+   PG   P + +AGT
Sbjct: 905  RDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGT 964

Query: 100  HVLYPIPESSSDSPLAISGGESSLLPTRPTCLSHALLPSDHS 141
                 +P  S   PLA S    +  P+ P+       P  HS
Sbjct: 965  GKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHS 1006


>gi|16418357 ankyrin repeat domain 40 [Homo sapiens]
          Length = 368

 Score = 37.0 bits (84), Expect = 0.066
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 16/110 (14%)

Query: 587 LQRQKSLKAKMNRRACLGSLQELESEPVIQVTVGSAKYESAYQAVVWKIDRLPDKNSSLD 646
           L  QK  + ++   A LG ++E++      V V S    + +  + W   R        +
Sbjct: 4   LLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHWACKR--------N 55

Query: 647 HPHCLSYKLELGSDQEIPSDWYPFATVQFSVPDTCASRTEVRS-LGVESD 695
           H   +SY L+ G+D+EI        T +  +P    SR E+R  +GVE +
Sbjct: 56  HGQVVSYLLKSGADKEI-------LTTKGEMPVQLTSRREIRKIMGVEEE 98


>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
          Length = 756

 Score = 36.6 bits (83), Expect = 0.086
 Identities = 34/106 (32%), Positives = 45/106 (42%), Gaps = 10/106 (9%)

Query: 51  PSGSSSTSSTPLSSPIVDFYFSPGPP---SNSPLSTPTKDFPGFPGIPKAGTHVLYPIPE 107
           P+G S  +  P   P  D   +P PP   S +P   PT D  G P +P  G     P+P 
Sbjct: 565 PTGDSEATPVP---PTGDSETAPVPPTGDSGAPPVPPTGD-SGAPPVPPTGDSGAPPVPP 620

Query: 108 S-SSDSPLAISGGESSLLPTRPTCLSHA--LLPSDHSCTHPTPKVG 150
           +  S +P     G+S   P  PT  S A  + P+  S   P P  G
Sbjct: 621 TGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTG 666



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 32/106 (30%), Positives = 41/106 (38%), Gaps = 10/106 (9%)

Query: 51  PSGSSSTSSTPLSSPIVDFYFSPGPP---SNSPLSTPTKDFPGFPGIPKAGTHVLYPIPE 107
           P+G S     P   P  D    P PP   S +P   PT D  G P +P  G     P+P 
Sbjct: 598 PTGDSGAPPVP---PTGDSGAPPVPPTGDSGAPPVPPTGD-SGAPPVPPTGDSGAPPVPP 653

Query: 108 SS-SDSPLAISGGESSLLPTRPT--CLSHALLPSDHSCTHPTPKVG 150
           +  S +P     G+S   P  PT       + P+  S   P P  G
Sbjct: 654 TGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTG 699


>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 3859

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 35/120 (29%), Positives = 53/120 (44%), Gaps = 12/120 (10%)

Query: 60  TPLSSPIVDFYFSPGP-----PSNSPL-STPTKDFPGFPGIPKAGTHVLYPIPESSSDSP 113
           TP  +P+V    + GP     P++SP+    + D P  P  P A + V    P + +DSP
Sbjct: 122 TPADNPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPVTP-ADSPVF---PVTPADSP 177

Query: 114 L-AISGGESSLLPTRPT-CLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGFQSDDLP 171
           L  ++  +S L P  P    +  + P+D    H TP  G    V P  +  +   S D P
Sbjct: 178 LFPVTPADSPLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSP 237



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 13/92 (14%)

Query: 45  PGLREFPSGSSSTSSTPLSSPIVDFYFSPGPPSNSPLSTPTK-DFPGFPGIPKAGTHVLY 103
           P L   P+ S +   TP  SPIV     P  P+N P+   T  D P  P IP  G  V  
Sbjct: 536 PVLSVTPAESPAIPVTPADSPIV-----PVTPANGPVVPVTSADSPFVPVIPADGPVVPV 590

Query: 104 P------IPESSSDSP-LAISGGESSLLPTRP 128
                  +P + +DSP L+++  +S  +P  P
Sbjct: 591 TPADSPVVPVTPADSPVLSVTLADSPAVPVTP 622



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 22/96 (22%)

Query: 51   PSGSSSTSSTPLSSPIVDFYFSPGPPSN-SPLSTPTKDFPGFPGIPKAGTHVL------- 102
            P+ S     TP + P+V     P PP+N S +   +   P  P IP  G  VL       
Sbjct: 2310 PADSPVVPVTPANIPVV-----PVPPANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDVL 2364

Query: 103  ---------YPIPESSSDSPLAISGGESSLLPTRPT 129
                      P+P+ + D  ++++  +S ++P  PT
Sbjct: 2365 VVLVSPTDGIPVPDLADDPVVSVTTSDSPVIPVTPT 2400


>gi|31543452 PX domain containing serine/threonine kinase [Homo
           sapiens]
          Length = 578

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 17/104 (16%)

Query: 52  SGSSSTSSTPLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSD 111
           + + S +S+PL+SP      SP PPS S +S      P  P  P A      P+P +S++
Sbjct: 487 NSAGSGASSPLTSPS-----SPTPPSTSGISALPPPPP--PPPPPAA-----PLPPASTE 534

Query: 112 SPL-----AISGGESSLLPTRPTCLSHALLPSDHSCTHPTPKVG 150
           +P      A++G     L +         L    +C H  PK+G
Sbjct: 535 APAQLSSQAVNGMSRGALLSSIQNFQKGTLRKAKTCDHSAPKIG 578


>gi|116292174 fidgetin-like 2 [Homo sapiens]
          Length = 653

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 29/121 (23%), Positives = 47/121 (38%), Gaps = 15/121 (12%)

Query: 7   GKWVTFDDDPAVQSSQKSKNFPLENQGVCRPNGLKLNLPGLREFPSGSSSTSSTPLSSPI 66
           G++  +  +PA        ++P  + G CR NG +   PG  E  SG       PL    
Sbjct: 276 GRYRKYAYEPAKAPVADGASYPAADNGECRGNGFRAKPPGAAEEASGKYG-GGVPLK--- 331

Query: 67  VDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESSSDSPLAISGGESSLLPT 126
                  G P   P   P + FP     P+ G    + +P  S ++P  +  G   L+ +
Sbjct: 332 -----VLGSPVYGPQLEPFEKFPERAPAPRGG----FAVP--SGETPKGVDPGALELVTS 380

Query: 127 R 127
           +
Sbjct: 381 K 381


>gi|29294655 melanoma antigen family C, 3 isoform 2 [Homo sapiens]
          Length = 346

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 26/128 (20%)

Query: 50  FPSGSSSTSSTPLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIPKAGTHVLYPIPESS 109
           FPS SS +SS+PLSSP+         PS   L  P  +      +P AG   + P+P+S 
Sbjct: 51  FPSSSSLSSSSPLSSPL---------PSTLILGVPEDE-----DMPAAG---MPPLPQSP 93

Query: 110 SDSPLAISGGESSLLPTRPTCLSHALLPSDHSCTHPTPKVGLPDEVNPQQAESLGF---- 165
            + P     G   + P  P   S    P D SC+ P     L +E + ++ ++  +    
Sbjct: 94  PEIP---PQGPPKISPQGPP-QSPPQSPLD-SCSSPLLWTRLDEESSSEEEDTATWHALP 148

Query: 166 QSDDLPQF 173
           +S+ LP++
Sbjct: 149 ESESLPRY 156


>gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]
          Length = 922

 Score = 35.0 bits (79), Expect = 0.25
 Identities = 40/149 (26%), Positives = 58/149 (38%), Gaps = 14/149 (9%)

Query: 37  PNGLKLNLPGLREFPSGS-SSTSSTPLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIP 95
           PN   +  P L   P  S  ST++TP+ S        PGP +    +TPT   PG     
Sbjct: 310 PNPTVIRTPSLPTAPVTSIHSTTTTPVPSIFSGLVSLPGPSATPTAATPT---PGPTPRS 366

Query: 96  KAGTHVLY--------PIPESSSDSPLAISGGESSLLPTRPTCLSHALLPSDHSCTHPTP 147
             G+   +         +P S+S S  + S   S+ L +    L   L P+    ++PTP
Sbjct: 367 TLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSNPTP 426

Query: 148 KVGLPDEVNPQQAESLGFQSDDLPQFQYF 176
            +       P  A  LG  S  L   + F
Sbjct: 427 VIA--GGSTPSVAGPLGVNSPLLSALKGF 453


>gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]
          Length = 944

 Score = 35.0 bits (79), Expect = 0.25
 Identities = 40/149 (26%), Positives = 58/149 (38%), Gaps = 14/149 (9%)

Query: 37  PNGLKLNLPGLREFPSGS-SSTSSTPLSSPIVDFYFSPGPPSNSPLSTPTKDFPGFPGIP 95
           PN   +  P L   P  S  ST++TP+ S        PGP +    +TPT   PG     
Sbjct: 332 PNPTVIRTPSLPTAPVTSIHSTTTTPVPSIFSGLVSLPGPSATPTAATPT---PGPTPRS 388

Query: 96  KAGTHVLY--------PIPESSSDSPLAISGGESSLLPTRPTCLSHALLPSDHSCTHPTP 147
             G+   +         +P S+S S  + S   S+ L +    L   L P+    ++PTP
Sbjct: 389 TLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSNPTP 448

Query: 148 KVGLPDEVNPQQAESLGFQSDDLPQFQYF 176
            +       P  A  LG  S  L   + F
Sbjct: 449 VIA--GGSTPSVAGPLGVNSPLLSALKGF 475


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,309,674
Number of Sequences: 37866
Number of extensions: 1584306
Number of successful extensions: 5168
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 4976
Number of HSP's gapped (non-prelim): 291
length of query: 735
length of database: 18,247,518
effective HSP length: 110
effective length of query: 625
effective length of database: 14,082,258
effective search space: 8801411250
effective search space used: 8801411250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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