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Search of human proteins with 26667227
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|26667227 eyes absent 2 isoform a [Homo sapiens]
(538 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|26667227 eyes absent 2 isoform a [Homo sapiens] 1103 0.0
gi|26667240 eyes absent 2 isoform b [Homo sapiens] 1103 0.0
gi|26667235 eyes absent 2 isoform a [Homo sapiens] 1103 0.0
gi|26667232 eyes absent 2 isoform a [Homo sapiens] 1103 0.0
gi|26667230 eyes absent 2 isoform c [Homo sapiens] 1042 0.0
gi|19923100 eyes absent 1 isoform b [Homo sapiens] 684 0.0
gi|26667216 eyes absent 1 isoform b [Homo sapiens] 684 0.0
gi|26667222 eyes absent 1 isoform a [Homo sapiens] 684 0.0
gi|26667219 eyes absent 1 isoform c [Homo sapiens] 625 e-179
gi|98991763 eyes absent 4 isoform b [Homo sapiens] 607 e-173
gi|98991760 eyes absent 4 isoform a [Homo sapiens] 607 e-173
gi|26667257 eyes absent 4 isoform d [Homo sapiens] 588 e-168
gi|26667243 eyes absent 3 [Homo sapiens] 459 e-129
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 53 8e-07
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 52 2e-06
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 49 2e-05
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s... 46 1e-04
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 46 1e-04
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 46 1e-04
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 44 4e-04
gi|62122917 filaggrin family member 2 [Homo sapiens] 42 0.002
gi|55770860 T-box 15 [Homo sapiens] 42 0.002
gi|122937492 SET domain containing 5 [Homo sapiens] 40 0.005
gi|33946327 nucleoporin 214kDa [Homo sapiens] 39 0.016
gi|54607108 zinc finger, MIZ-type containing 2 isoform 1 [Homo s... 38 0.020
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 37 0.060
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 37 0.060
gi|39777614 SS18-like protein 1 [Homo sapiens] 37 0.060
gi|46370086 transcription factor 12 isoform c [Homo sapiens] 36 0.078
gi|41281683 disabled homolog 2 interacting protein isoform 2 [Ho... 35 0.13
>gi|26667227 eyes absent 2 isoform a [Homo sapiens]
Length = 538
Score = 1103 bits (2854), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1 MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
Query: 61 QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG
Sbjct: 61 QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
Query: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
Query: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
Query: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
Query: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
Query: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
Query: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
>gi|26667240 eyes absent 2 isoform b [Homo sapiens]
Length = 543
Score = 1103 bits (2854), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 6 MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 65
Query: 61 QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG
Sbjct: 66 QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 125
Query: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 126 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 185
Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 186 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 245
Query: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 246 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 305
Query: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 306 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 365
Query: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 366 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 425
Query: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 426 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 485
Query: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 486 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 543
>gi|26667235 eyes absent 2 isoform a [Homo sapiens]
Length = 538
Score = 1103 bits (2854), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1 MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
Query: 61 QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG
Sbjct: 61 QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
Query: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
Query: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
Query: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
Query: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
Query: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
Query: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
>gi|26667232 eyes absent 2 isoform a [Homo sapiens]
Length = 538
Score = 1103 bits (2854), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1 MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
Query: 61 QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG
Sbjct: 61 QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
Query: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
Query: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
Query: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
Query: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
Query: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
Query: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
>gi|26667230 eyes absent 2 isoform c [Homo sapiens]
Length = 514
Score = 1042 bits (2694), Expect = 0.0
Identities = 514/538 (95%), Positives = 514/538 (95%), Gaps = 24/538 (4%)
Query: 1 MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1 MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
Query: 61 QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS
Sbjct: 61 QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS---------------------- 98
Query: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 99 --FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 156
Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 157 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 216
Query: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 217 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 276
Query: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 277 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 336
Query: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 337 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 396
Query: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 397 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 456
Query: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 457 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514
>gi|19923100 eyes absent 1 isoform b [Homo sapiens]
Length = 592
Score = 684 bits (1765), Expect = 0.0
Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)
Query: 51 SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105
+R P +LP S MAAYGQTQ++ G+QQAT Y YP P Q YGI SY IKTE
Sbjct: 91 NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 150
Query: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158
L+ S PGQ+GFLSYG+SFST GQ+PY+YQM G++ G Y G N L N++GF S
Sbjct: 151 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 210
Query: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216
QDYPSYP F Q QY QYY SS Y Y+ +S+ P+ P + +TY LQE + +Q+
Sbjct: 211 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 270
Query: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276
EY+T + PSTP K+ D+DR R SDGK RGR +R+++PSP D+++ERVF+WDLD
Sbjct: 271 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 330
Query: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336
ETII+FHSLLTG++A+RYG+D TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 331 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 390
Query: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396
SSDDNGQDLSTYNF DGF ++A ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 391 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 450
Query: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456
NVGGL+G KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 451 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 510
Query: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516
KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 511 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 570
Query: 517 FWRISCHADLEALRHALELEYL 538
FWRIS H+DL AL HALELEYL
Sbjct: 571 FWRISSHSDLMALHHALELEYL 592
>gi|26667216 eyes absent 1 isoform b [Homo sapiens]
Length = 592
Score = 684 bits (1765), Expect = 0.0
Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)
Query: 51 SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105
+R P +LP S MAAYGQTQ++ G+QQAT Y YP P Q YGI SY IKTE
Sbjct: 91 NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 150
Query: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158
L+ S PGQ+GFLSYG+SFST GQ+PY+YQM G++ G Y G N L N++GF S
Sbjct: 151 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 210
Query: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216
QDYPSYP F Q QY QYY SS Y Y+ +S+ P+ P + +TY LQE + +Q+
Sbjct: 211 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 270
Query: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276
EY+T + PSTP K+ D+DR R SDGK RGR +R+++PSP D+++ERVF+WDLD
Sbjct: 271 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 330
Query: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336
ETII+FHSLLTG++A+RYG+D TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 331 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 390
Query: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396
SSDDNGQDLSTYNF DGF ++A ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 391 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 450
Query: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456
NVGGL+G KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 451 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 510
Query: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516
KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 511 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 570
Query: 517 FWRISCHADLEALRHALELEYL 538
FWRIS H+DL AL HALELEYL
Sbjct: 571 FWRISSHSDLMALHHALELEYL 592
>gi|26667222 eyes absent 1 isoform a [Homo sapiens]
Length = 559
Score = 684 bits (1765), Expect = 0.0
Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)
Query: 51 SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105
+R P +LP S MAAYGQTQ++ G+QQAT Y YP P Q YGI SY IKTE
Sbjct: 58 NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 117
Query: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158
L+ S PGQ+GFLSYG+SFST GQ+PY+YQM G++ G Y G N L N++GF S
Sbjct: 118 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 177
Query: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216
QDYPSYP F Q QY QYY SS Y Y+ +S+ P+ P + +TY LQE + +Q+
Sbjct: 178 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 237
Query: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276
EY+T + PSTP K+ D+DR R SDGK RGR +R+++PSP D+++ERVF+WDLD
Sbjct: 238 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 297
Query: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336
ETII+FHSLLTG++A+RYG+D TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 298 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 357
Query: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396
SSDDNGQDLSTYNF DGF ++A ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 358 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 417
Query: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456
NVGGL+G KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 418 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 477
Query: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516
KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 478 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 537
Query: 517 FWRISCHADLEALRHALELEYL 538
FWRIS H+DL AL HALELEYL
Sbjct: 538 FWRISSHSDLMALHHALELEYL 559
>gi|26667219 eyes absent 1 isoform c [Homo sapiens]
Length = 557
Score = 625 bits (1613), Expect = e-179
Identities = 315/497 (63%), Positives = 370/497 (74%), Gaps = 39/497 (7%)
Query: 51 SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHS 110
+R P +LP S MAAYGQTQ++ G+QQAT Y YP P Q YGI SY IKTE L+ S
Sbjct: 91 NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGIKTEGGLSQS 150
Query: 111 --PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGSVHQDY 163
PGQ+GFLSYG+SFST GQ+PY+YQM G++ G Y G N L N++GF S QDY
Sbjct: 151 QSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDY 210
Query: 164 PSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSSESLAG 221
PSYP F Q QY QYY SS Y Y+ +S+ P+ P + +TY LQE + +Q+
Sbjct: 211 PSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTA 270
Query: 222 EYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIII 281
EY+T + PSTP K+ D+DR R SDGK RGR +R+++PSP D+++ERVF+WDLDETII+
Sbjct: 271 EYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIV 330
Query: 282 FHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDN 341
FHSLLTG++A+RYG+ +CDQ+H+DDVSSDDN
Sbjct: 331 FHSLLTGSYANRYGR------------------------------ECDQVHIDDVSSDDN 360
Query: 342 GQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGL 401
GQDLSTYNF DGF ++A ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKNNVGGL
Sbjct: 361 GQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGL 420
Query: 402 IGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLY 461
+G KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALAKVLLY
Sbjct: 421 LGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLY 480
Query: 462 GLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRIS 521
GLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MPFWRIS
Sbjct: 481 GLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRIS 540
Query: 522 CHADLEALRHALELEYL 538
H+DL AL HALELEYL
Sbjct: 541 SHSDLMALHHALELEYL 557
>gi|98991763 eyes absent 4 isoform b [Homo sapiens]
Length = 616
Score = 607 bits (1564), Expect = e-173
Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)
Query: 40 KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97
+SA QL+ S+ P +L + M+AY GQTQYS G+QQ YTAY Q Y +P
Sbjct: 110 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 168
Query: 98 SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144
+Y +IKTE L+ SP QSG LSY FST GQ+PY+YQM G++
Sbjct: 169 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 228
Query: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203
N + N+ F QDYPSY F Q+QY QYY +S Y+ +++ +P STSTY
Sbjct: 229 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 288
Query: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263
LQE+ + NQ GE++T PSTP K+ D +R R+S K RGR R ++PSP
Sbjct: 289 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 341
Query: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323
D+++ERVFVWDLDETII+FHSLLTG++A +YGKD +V +GL MEEMIFNLADTHLFFN
Sbjct: 342 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 401
Query: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383
DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A ANLCL +GV GGVDWMRKLAFR
Sbjct: 402 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 461
Query: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443
YRRVKE+YNTYKNNVGGL+G KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 462 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 521
Query: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503
VLVTTTQLIPALAKVLLY LG FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 522 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 581
Query: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
VEEEQ AKKHNMPFWRIS H+DL AL ALELEYL
Sbjct: 582 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616
>gi|98991760 eyes absent 4 isoform a [Homo sapiens]
Length = 639
Score = 607 bits (1564), Expect = e-173
Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)
Query: 40 KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97
+SA QL+ S+ P +L + M+AY GQTQYS G+QQ YTAY Q Y +P
Sbjct: 133 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 191
Query: 98 SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144
+Y +IKTE L+ SP QSG LSY FST GQ+PY+YQM G++
Sbjct: 192 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 251
Query: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203
N + N+ F QDYPSY F Q+QY QYY +S Y+ +++ +P STSTY
Sbjct: 252 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 311
Query: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263
LQE+ + NQ GE++T PSTP K+ D +R R+S K RGR R ++PSP
Sbjct: 312 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 364
Query: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323
D+++ERVFVWDLDETII+FHSLLTG++A +YGKD +V +GL MEEMIFNLADTHLFFN
Sbjct: 365 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 424
Query: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383
DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A ANLCL +GV GGVDWMRKLAFR
Sbjct: 425 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 484
Query: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443
YRRVKE+YNTYKNNVGGL+G KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 485 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 544
Query: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503
VLVTTTQLIPALAKVLLY LG FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 545 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 604
Query: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
VEEEQ AKKHNMPFWRIS H+DL AL ALELEYL
Sbjct: 605 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639
>gi|26667257 eyes absent 4 isoform d [Homo sapiens]
Length = 639
Score = 588 bits (1515), Expect = e-168
Identities = 308/515 (59%), Positives = 374/515 (72%), Gaps = 24/515 (4%)
Query: 40 KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97
+SA QL+ S+ P +L + M+AY GQTQYS G+QQ YTAY Q Y +P
Sbjct: 133 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 191
Query: 98 SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144
+Y +IKTE L+ SP QSG LSY FST GQ+PY+YQM G++
Sbjct: 192 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 251
Query: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203
N + N+ F QDYPSY F Q+QY QYY +S Y+ +++ +P STSTY
Sbjct: 252 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 311
Query: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263
LQE+ + NQ GE++T PSTP K+ D +R R+S K RGR R ++PSP
Sbjct: 312 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 364
Query: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323
D+++ERVFVWDLDETII+FHSLLTG++A +YGKD +V +GL MEEMIFNLADTHLFFN
Sbjct: 365 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 424
Query: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383
DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A ANLCL +GV GGVDWMRKLAFR
Sbjct: 425 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 484
Query: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443
YRRVKE+YNTYKNNVGGL+G KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 485 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 544
Query: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503
VLVTTTQLIPALAKVLLY LG FPIENIYSATK GKESCFERI+ RFG YVVIGDG
Sbjct: 545 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDG 604
Query: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
+EE A +HNMPFWRIS H+DL AL ALELEYL
Sbjct: 605 RDEEHAANQHNMPFWRISSHSDLLALHQALELEYL 639
>gi|26667243 eyes absent 3 [Homo sapiens]
Length = 573
Score = 459 bits (1180), Expect = e-129
Identities = 254/516 (49%), Positives = 333/516 (64%), Gaps = 17/516 (3%)
Query: 38 ITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIP 97
I +S+ SQ++S + P + A GQTQY +QQ PY YP Q YG+P
Sbjct: 60 IPRSSNDYTSQMYSAKPYAHILSVPVSETAYPGQTQYQT-LQQTQPYAVYPQATQTYGLP 118
Query: 98 SYS-----IKTEDSL--NHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT---GFYQGG 147
+ +K E L SP Q L+ + +TS + Y+Y + ++
Sbjct: 119 PFGALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQASSTNASLISTS 178
Query: 148 NGLGN--AAGFGSV-HQDYPSYPGFPQSQYPQYY-GSSYNPPYVPASSICPSPLSTSTYV 203
+ + N AA S+ +QDYP+Y Q+QY Y SS+ S + L+ +TY
Sbjct: 179 STIANIPAAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSDAESTTLAATTYQ 238
Query: 204 LQEASHNVPNQSSESLA-GEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPA 262
++ S P +++ L+ G+ +T S DTD R + + R KR +D + +
Sbjct: 239 SEKPSVMAPAPAAQRLSSGDPSTSPSLSQTTPSKDTDDQSRKNMTS-KNRGKRKADATSS 297
Query: 263 GDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFF 322
D+E+ERVF+WDLDETIIIFHSLLTG++A +YGKD T + GL MEEMIF +ADTHLFF
Sbjct: 298 QDSELERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFF 357
Query: 323 NDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAF 382
NDLE+CDQ+HV+DV+SDDNGQDLS Y+FS DGF S + GV GGVDWMRKLAF
Sbjct: 358 NDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAF 417
Query: 383 RYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCV 442
RYR+V+E+Y+ +K+NVGGL+ ++E +LRAE+E LTD WL +LK+L LI SR NCV
Sbjct: 418 RYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCV 477
Query: 443 NVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGD 502
NVL+TTTQL+PALAKVLLYGLG +FPIENIYSATK GKESCFERI+ RFG+K YVVIGD
Sbjct: 478 NVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGD 537
Query: 503 GVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
G +EE AK+HNMPFWRI+ H DL +L ALEL++L
Sbjct: 538 GRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL 573
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 52.8 bits (125), Expect = 8e-07
Identities = 62/224 (27%), Positives = 85/224 (37%), Gaps = 27/224 (12%)
Query: 67 AAYGQTQYSAGI-QQATPYT------AYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSY 119
A YGQT Y+ Q T YT AY P Q YG +Y T + +Y
Sbjct: 59 ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118
Query: 120 GS-----SFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQY 174
G+ ++ P +P +Y T + Q N G S + SY QS Y
Sbjct: 119 GTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYG--QQSSY 176
Query: 175 PQYYGSSYNPPYVPASSICPSPLS--TSTYVLQE-------ASHNVPNQSSESLA--GEY 223
Q +SY PP + S PS S +S+Y Q +S V Q S + GE
Sbjct: 177 GQQPPTSY-PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGEN 235
Query: 224 NTHNGPSTPAK-EGDTDRPHRASDGKLRGRSKRSSDPSPAGDNE 266
+ +GP + G DR + G+ GR S G N+
Sbjct: 236 RSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNK 279
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/169 (31%), Positives = 73/169 (43%), Gaps = 29/169 (17%)
Query: 79 QQATP-YTAYPPP---------AQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPT 128
QQAT Y AYP +Q YG SYS ++ + GQS + SYG S +T
Sbjct: 8 QQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYG 67
Query: 129 GQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQ----YYG----- 179
QS T Q +G+TG G G++ S + SYPG+ Q P YG
Sbjct: 68 TQS--TPQGYGSTG------GYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQS 119
Query: 180 SSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNG 228
SSY P + S PS Q+ S+N P + +YN+ +G
Sbjct: 120 SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQ--NQYNSSSG 166
Score = 42.0 bits (97), Expect = 0.001
Identities = 42/124 (33%), Positives = 49/124 (39%), Gaps = 16/124 (12%)
Query: 63 STAMAAYGQTQYSA-GIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGS 121
ST + YGQ+ YS+ G Q T Y P Q YG + + QS SYG
Sbjct: 44 STDTSGYGQSSYSSYGQSQNTGYGTQSTP-QGYG---------STGGYGSSQSSQSSYGQ 93
Query: 122 SFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSS 181
S GQ P G+ G + G GS Q PSY G QS Q S
Sbjct: 94 QSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQS-GSYSQQ-PSYGGQQQSYGQQ---QS 148
Query: 182 YNPP 185
YNPP
Sbjct: 149 YNPP 152
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 48.5 bits (114), Expect = 2e-05
Identities = 61/206 (29%), Positives = 86/206 (41%), Gaps = 36/206 (17%)
Query: 68 AYGQTQYSAGIQQATPYTAYPPP-AQAYGIPSYSI----KTEDSLNHSPGQSGFLSYGSS 122
+YGQ S G QQ+ Y+ Y P +Q YG S S +T DS ++ SG+ SYG S
Sbjct: 6 SYGQ---SGGEQQS--YSTYGNPGSQGYGQASQSYSGYGQTTDS-SYGQNYSGYSSYGQS 59
Query: 123 FSTSPTG-----QSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQ--DYPSYPGF-PQSQY 174
+S S G QS Y+ Q + G Q G+ G + DY + QS Y
Sbjct: 60 YSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGY 119
Query: 175 PQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTH--NGPSTP 232
Q+ G SY+ S Y Q S++ QS S Y+ H +
Sbjct: 120 DQHQG-SYD--------------EQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDV 164
Query: 233 AKEGDTDRPHRASDGKLRGRSKRSSD 258
++ G+ +R + S G RGR D
Sbjct: 165 SRYGEDNRGYGGSQGGGRGRGGYDKD 190
>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
sapiens]
Length = 354
Score = 45.8 bits (107), Expect = 1e-04
Identities = 54/200 (27%), Positives = 73/200 (36%), Gaps = 43/200 (21%)
Query: 67 AAYGQTQYSAGI-QQATPYT------AYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSY 119
A YGQT Y+ Q T YT AY P Q YG +Y T + +Y
Sbjct: 59 ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118
Query: 120 GSSFSTSPTGQSP---------------YTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYP 164
G+ + GQ P T Q +TG Y + G+G + YP
Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYN-----QPSLGYGQSNYSYP 173
Query: 165 ----SYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPN----QSS 216
SYP P + P Y +SY SS P+ S+Y Q+ ++ P+ QSS
Sbjct: 174 QVPGSYPMQPVTAPPSYPPTSY-------SSTQPTSYDQSSY-SQQNTYGQPSSYGQQSS 225
Query: 217 ESLAGEYNTHNGPSTPAKEG 236
Y S P + G
Sbjct: 226 YGQQSSYGQQPPTSYPPQTG 245
Score = 30.0 bits (66), Expect = 5.6
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 15/115 (13%)
Query: 55 PRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIP-SYSIKTEDSLNHSPGQ 113
P P QP TA +Y T YS+ + ++Y YG P SY ++ S GQ
Sbjct: 176 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQ 234
Query: 114 SGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
SY T Q+P Y Q + G + F QD+PS G
Sbjct: 235 QPPTSYPP--QTGSYSQAPSQYS--------QQSSSYGQQSSF---RQDHPSSMG 276
>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
sapiens]
Length = 655
Score = 45.8 bits (107), Expect = 1e-04
Identities = 54/200 (27%), Positives = 73/200 (36%), Gaps = 43/200 (21%)
Query: 67 AAYGQTQYSAGI-QQATPYT------AYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSY 119
A YGQT Y+ Q T YT AY P Q YG +Y T + +Y
Sbjct: 59 ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118
Query: 120 GSSFSTSPTGQSP---------------YTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYP 164
G+ + GQ P T Q +TG Y + G+G + YP
Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYN-----QPSLGYGQSNYSYP 173
Query: 165 ----SYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPN----QSS 216
SYP P + P Y +SY SS P+ S+Y Q+ ++ P+ QSS
Sbjct: 174 QVPGSYPMQPVTAPPSYPPTSY-------SSTQPTSYDQSSY-SQQNTYGQPSSYGQQSS 225
Query: 217 ESLAGEYNTHNGPSTPAKEG 236
Y S P + G
Sbjct: 226 YGQQSSYGQQPPTSYPPQTG 245
Score = 30.0 bits (66), Expect = 5.6
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 15/115 (13%)
Query: 55 PRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIP-SYSIKTEDSLNHSPGQ 113
P P QP TA +Y T YS+ + ++Y YG P SY ++ S GQ
Sbjct: 176 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQ 234
Query: 114 SGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
SY T Q+P Y Q + G + F QD+PS G
Sbjct: 235 QPPTSYPP--QTGSYSQAPSQYS--------QQSSSYGQQSSF---RQDHPSSMG 276
>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
Length = 656
Score = 45.8 bits (107), Expect = 1e-04
Identities = 54/200 (27%), Positives = 73/200 (36%), Gaps = 43/200 (21%)
Query: 67 AAYGQTQYSAGI-QQATPYT------AYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSY 119
A YGQT Y+ Q T YT AY P Q YG +Y T + +Y
Sbjct: 59 ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118
Query: 120 GSSFSTSPTGQSP---------------YTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYP 164
G+ + GQ P T Q +TG Y + G+G + YP
Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYN-----QPSLGYGQSNYSYP 173
Query: 165 ----SYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPN----QSS 216
SYP P + P Y +SY SS P+ S+Y Q+ ++ P+ QSS
Sbjct: 174 QVPGSYPMQPVTAPPSYPPTSY-------SSTQPTSYDQSSY-SQQNTYGQPSSYGQQSS 225
Query: 217 ESLAGEYNTHNGPSTPAKEG 236
Y S P + G
Sbjct: 226 YGQQSSYGQQPPTSYPPQTG 245
Score = 30.0 bits (66), Expect = 5.6
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 15/115 (13%)
Query: 55 PRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIP-SYSIKTEDSLNHSPGQ 113
P P QP TA +Y T YS+ + ++Y YG P SY ++ S GQ
Sbjct: 176 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQ 234
Query: 114 SGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
SY T Q+P Y Q + G + F QD+PS G
Sbjct: 235 QPPTSYPP--QTGSYSQAPSQYS--------QQSSSYGQQSSF---RQDHPSSMG 276
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 43.9 bits (102), Expect = 4e-04
Identities = 54/206 (26%), Positives = 74/206 (35%), Gaps = 49/206 (23%)
Query: 67 AAYGQTQYSAGIQQ-------ATPYT------AYPPPAQAYGIPSYSIKTEDSLNHSPGQ 113
A YGQT Y+ Q +T YT AY P Q YG +Y T
Sbjct: 59 ATYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASY 118
Query: 114 SGFLSYGSSFSTSPTGQSP---------------YTYQMHGTTGFYQGGNGLGNAAGFGS 158
+ +YG+ + GQ P T Q +TG Y + G+G
Sbjct: 119 AAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYN-----QPSLGYGQ 173
Query: 159 VHQDYP----SYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPN- 213
+ YP SYP P + P Y +SY SS P+ S+Y Q+ ++ P+
Sbjct: 174 SNYSYPQVPGSYPMQPVTAPPSYPPTSY-------SSTQPTSYDQSSY-SQQNTYGQPSS 225
Query: 214 ---QSSESLAGEYNTHNGPSTPAKEG 236
QSS Y S P + G
Sbjct: 226 YGQQSSYGQQSSYGQQPPTSYPPQTG 251
Score = 30.0 bits (66), Expect = 5.6
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 15/115 (13%)
Query: 55 PRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIP-SYSIKTEDSLNHSPGQ 113
P P QP TA +Y T YS+ + ++Y YG P SY ++ S GQ
Sbjct: 182 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQ 240
Query: 114 SGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
SY T Q+P Y Q + G + F QD+PS G
Sbjct: 241 QPPTSYPP--QTGSYSQAPSQYS--------QQSSSYGQQSSF---RQDHPSSMG 282
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 19/199 (9%)
Query: 70 GQTQYSAGIQQATPYTAYPPPA-QAYGIPSYSIKTEDSL--NHSPGQSGFLSYGSSFSTS 126
G QY +G Q++ + + + Q+ G + ++ S HS G S YG S
Sbjct: 579 GFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQ 638
Query: 127 PTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQ-------SQYPQY-Y 178
+G + +TGF Q G+G G ++GFG GF Q S Y Q+ +
Sbjct: 639 TSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGF 698
Query: 179 GSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDT 238
GSS + Y S S TS + H + + S S G++ + +G S+ + +
Sbjct: 699 GSSQSSGYGQHGS---SSGQTSGF----GQHELSSGQSSSF-GQHGSGSGQSSGFGQHGS 750
Query: 239 DRPHRASDGKLRGRSKRSS 257
+ G+ RS +SS
Sbjct: 751 GSGQSSGFGQHESRSGQSS 769
Score = 37.7 bits (86), Expect = 0.027
Identities = 44/157 (28%), Positives = 62/157 (39%), Gaps = 16/157 (10%)
Query: 109 HSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
HS G S YG S +G + +TGF Q G+G G +AGFG G
Sbjct: 773 HSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSG 832
Query: 169 F-------PQSQYPQY-YGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLA 220
F QS Y Q+ GSS + Y S S TS + +S S
Sbjct: 833 FGQHESRSHQSSYGQHGSGSSQSSGYGQHGS---SSGQTSGFGQHRSS-----SGQYSGF 884
Query: 221 GEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSS 257
G++ + +G S+ + T + G+ RS +SS
Sbjct: 885 GQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSS 921
Score = 35.4 bits (80), Expect = 0.13
Identities = 32/118 (27%), Positives = 50/118 (42%), Gaps = 9/118 (7%)
Query: 70 GQTQYSAGIQQATPYTAYPPPA-QAYGIPSYSIKTEDSL--NHSPGQSGFLSYGSSFSTS 126
G QY +G Q+ + + + Q+ G + ++ S H G S YG S+S
Sbjct: 806 GFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSS 865
Query: 127 PTGQSPYTYQMHGTTGFYQG----GNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
GQ+ Q ++G Y G G+G G ++GFG Y GF Q + + S
Sbjct: 866 --GQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSS 921
Score = 35.4 bits (80), Expect = 0.13
Identities = 44/169 (26%), Positives = 70/169 (41%), Gaps = 9/169 (5%)
Query: 70 GQTQYSAGIQQATPYTAYPPPA-QAYGIPSYSIKTEDSL--NHSPGQSGFLSYGSSFSTS 126
G Q+ +G Q++ + + + Q+ G Y ++ S H G S YG S S
Sbjct: 1037 GFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNS 1096
Query: 127 --PTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNP 184
+G + ++GF Q G+G G ++GFG GF Q +Y + SSY
Sbjct: 1097 GQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEY-RSGQSSYGQ 1155
Query: 185 PYVPA--SSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPST 231
+ SS C S S H V + S +G++ + +G ST
Sbjct: 1156 HGTGSSQSSGCGQHESGSGPTTSFGQH-VSGSDNFSSSGQHISDSGQST 1203
Score = 33.1 bits (74), Expect = 0.66
Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 8/86 (9%)
Query: 109 HSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
H G S YG S +G + +TGF Q G+G G ++GFG G
Sbjct: 546 HGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSG 605
Query: 169 F-------PQSQYPQY-YGSSYNPPY 186
F QS Y Q+ GSS + Y
Sbjct: 606 FGQHESRSGQSSYGQHSSGSSQSSGY 631
Score = 31.6 bits (70), Expect = 1.9
Identities = 53/218 (24%), Positives = 87/218 (39%), Gaps = 27/218 (12%)
Query: 70 GQTQYSAGIQQATPYTAYPPPAQAY-GIPSYSIKTEDSL--NHSPGQSGFLSYGSSFSTS 126
G Q+ +G Q++ + + + Y G + ++ S H G S YG S+S
Sbjct: 883 GFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSS 942
Query: 127 PTGQSPYTYQMHGT-----TGFYQGGNGLGNAAGFGSVHQDYPSYPGF-------PQSQY 174
GQ+ + + H + +GF Q G+G G ++GFG GF QS Y
Sbjct: 943 --GQT-FGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNY 999
Query: 175 PQY-YGSSYNPPYVPASSICPSPL------STSTYVLQEASHNVPNQSSESLAGEYNTHN 227
Q+ GSS + Y S S+S H + S G++ T +
Sbjct: 1000 GQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGF-GQHGTGS 1058
Query: 228 GPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDN 265
G S+ + ++ R ++S G+ S +SS G N
Sbjct: 1059 GQSSGFGQYES-RSRQSSYGQHGSGSSQSSGYGQHGSN 1095
Score = 30.4 bits (67), Expect = 4.3
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 6/62 (9%)
Query: 113 QSGFLSYGSSFSTSPTGQSPYTYQMHG---TTGFYQGGNGLGNAAGFGSVHQDYPSYPGF 169
+SG SYG S S Y HG T+GF Q G+G + GFG GF
Sbjct: 764 RSGQSSYGQHSSGSSQSSG---YGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGF 820
Query: 170 PQ 171
Q
Sbjct: 821 GQ 822
Score = 30.0 bits (66), Expect = 5.6
Identities = 19/54 (35%), Positives = 21/54 (38%)
Query: 118 SYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQ 171
SYG S S Y T+GF Q G G G + GFG GF Q
Sbjct: 542 SYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQ 595
Score = 29.6 bits (65), Expect = 7.3
Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 5/49 (10%)
Query: 128 TGQSPYTYQMHG-----TTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQ 171
T Y HG T+GF Q G+G G ++GFG GF Q
Sbjct: 459 TSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQ 507
>gi|55770860 T-box 15 [Homo sapiens]
Length = 496
Score = 41.6 bits (96), Expect = 0.002
Identities = 57/217 (26%), Positives = 81/217 (37%), Gaps = 31/217 (14%)
Query: 51 SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQAT-PYTAYPP---PAQAYGIPSYSIKTEDS 106
+RS L P + + Y + Q +G AT P + P P+ GIP T S
Sbjct: 297 ARSNMAALQSYPGLSDSGYNRLQ--SGTTSATQPSETFMPQRTPSLISGIP-----TPPS 349
Query: 107 LNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAG---FGSVHQDY 163
L PG S +YG + PT Q Y Q GN +++ FG H
Sbjct: 350 L---PGNSKMEAYGGQLGSFPTSQFQYV---------MQAGNAASSSSSPHMFGGSHMQQ 397
Query: 164 PSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLST--STYVLQEASHNVPNQSSESLAG 221
SY F YG YN P P + P LS ST + S+ + +G
Sbjct: 398 SSYNAFSLHNPYNLYG--YNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPSG 455
Query: 222 -EYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSS 257
E++ H +P + T+ G + G S + S
Sbjct: 456 MEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMS 492
>gi|122937492 SET domain containing 5 [Homo sapiens]
Length = 1442
Score = 40.0 bits (92), Expect = 0.005
Identities = 38/174 (21%), Positives = 65/174 (37%), Gaps = 14/174 (8%)
Query: 79 QQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQ---SPYTY 135
Q ++P+ +P + Y + +++ + +H +S S S P +P+T
Sbjct: 1257 QSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFT- 1315
Query: 136 QMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPS 195
GT G++ GN+ G + PS P Q G S +P S
Sbjct: 1316 ---GTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQ-----GPSDSPTSDSVSQSSTG 1367
Query: 196 PLSTSTYVLQEASHNVPNQSSESL--AGEYNTHNGPSTPAKEGDTDRPHRASDG 247
LS++++ S + + SL AG+ + A PHR S G
Sbjct: 1368 TLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRGSGG 1421
>gi|33946327 nucleoporin 214kDa [Homo sapiens]
Length = 2090
Score = 38.5 bits (88), Expect = 0.016
Identities = 60/250 (24%), Positives = 87/250 (34%), Gaps = 29/250 (11%)
Query: 40 KSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAY----G 95
K+ P S S P + P + Q G + + P PA
Sbjct: 1129 KNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGD 1188
Query: 96 IPSYSIKTEDSLNHSPGQSGFLSYGSSFSTS----------PTGQSPYTYQMHGTTGFYQ 145
S + K E ++ +P SG S SFS S PT S +T T +
Sbjct: 1189 KASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKE 1248
Query: 146 GGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYN-PPYVPASSICPSPLSTSTYVL 204
++G GS PSY P+S P S+ N P PA+S P++ S L
Sbjct: 1249 SSQPDAFSSGGGSK----PSYEAIPESSPPSGITSASNTTPGEPAAS-SSRPVAPSGTAL 1303
Query: 205 QEASHNVPNQSSE--------SLAGE-YNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKR 255
S + S+ SLAGE + +G + T ++AS L
Sbjct: 1304 STTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPT 1363
Query: 256 SSDPSPAGDN 265
+ P+G N
Sbjct: 1364 KTSGVPSGFN 1373
>gi|54607108 zinc finger, MIZ-type containing 2 isoform 1 [Homo
sapiens]
Length = 920
Score = 38.1 bits (87), Expect = 0.020
Identities = 49/160 (30%), Positives = 63/160 (39%), Gaps = 44/160 (27%)
Query: 68 AYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG------S 121
A G T AG Q P YP P QA +P +K S + PGQ +L G +
Sbjct: 234 AAGMTPLYAG--QRLPQHGYPGPPQAQPLPRQGVKRTYSEVY-PGQQ-YLQGGQYAPSTA 289
Query: 122 SFSTSPTGQSPY---TYQMH---------------GTTGFY----QGGNGLGNAAGFGSV 159
F+ SP GQ P +Y H G TG + + NG G + GSV
Sbjct: 290 QFAPSP-GQPPAPSPSYPGHRLPLQQGMTQSLSVPGPTGLHYKPTEQFNGQGASFNGGSV 348
Query: 160 HQDYP-------SYPGFPQSQYPQYYGSSYNPPYVPASSI 192
P S PG+P S P + PP P+SS+
Sbjct: 349 SYSQPGLSGPTRSIPGYPSSPLP----GNPTPPMTPSSSV 384
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 36.6 bits (83), Expect = 0.060
Identities = 41/158 (25%), Positives = 60/158 (37%), Gaps = 11/158 (6%)
Query: 114 SGFLSYGSSFSTSPTGQSP-YTYQMHGTTGFYQGGNGLGNAAGFGSVHQ--DY-----PS 165
+G+ SYG +++ G S Y+ H GG G G ++G+GS +Q +Y P
Sbjct: 674 AGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPK 733
Query: 166 YPGFPQ---SQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGE 222
+ G Q Q YGS Y S SP S + Q S S +
Sbjct: 734 HAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNS 793
Query: 223 YNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPS 260
YN+ G ++ + S G+ G S S S
Sbjct: 794 YNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGAS 831
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 36.6 bits (83), Expect = 0.060
Identities = 41/158 (25%), Positives = 60/158 (37%), Gaps = 11/158 (6%)
Query: 114 SGFLSYGSSFSTSPTGQSP-YTYQMHGTTGFYQGGNGLGNAAGFGSVHQ--DY-----PS 165
+G+ SYG +++ G S Y+ H GG G G ++G+GS +Q +Y P
Sbjct: 670 AGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPK 729
Query: 166 YPGFPQ---SQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGE 222
+ G Q Q YGS Y S SP S + Q S S +
Sbjct: 730 HAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNS 789
Query: 223 YNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPS 260
YN+ G ++ + S G+ G S S S
Sbjct: 790 YNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGAS 827
>gi|39777614 SS18-like protein 1 [Homo sapiens]
Length = 396
Score = 36.6 bits (83), Expect = 0.060
Identities = 36/148 (24%), Positives = 52/148 (35%), Gaps = 22/148 (14%)
Query: 59 PRQPSTAMAAYGQTQY-------SAGIQQATPYTAYPP-------PAQAYGIPSYSIKTE 104
P Q ++ GQ +Y S G + YP +Y SY E
Sbjct: 237 PSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFE 296
Query: 105 DSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQD 162
+S H G S + + + Q Y+ Q + + Y G G+GS
Sbjct: 297 ESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPG-----QQQGYGSAQGA 351
Query: 163 YPSYPGFPQSQYPQYYGSSYNPPYVPAS 190
YPG+ Q Q Q YGS P P++
Sbjct: 352 PSQYPGYQQGQ-GQQYGSYRAPQTAPSA 378
>gi|46370086 transcription factor 12 isoform c [Homo sapiens]
Length = 512
Score = 36.2 bits (82), Expect = 0.078
Identities = 43/170 (25%), Positives = 60/170 (35%), Gaps = 31/170 (18%)
Query: 84 YTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTS--PTGQSPYTYQM---- 137
Y AYP P Y + SP F S+ + PT T+ M
Sbjct: 2 YCAYPVPGMGSNSLMYYYNGKTVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGT 61
Query: 138 HGTTGFYQGGNGLGN----------------AAGFGSVHQ-DYPSYPGFPQSQYPQYYGS 180
H ++ + NG+ ++ +G++H D SYP P S P +
Sbjct: 62 HNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYP--PHSVSP----T 115
Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPS 230
N P SS S+S YV ASH P S+S+ G G S
Sbjct: 116 DINTSLPPMSSFHRGSTSSSPYVA--ASHTPPINGSDSILGTRGNAAGSS 163
>gi|41281683 disabled homolog 2 interacting protein isoform 2 [Homo
sapiens]
Length = 1065
Score = 35.4 bits (80), Expect = 0.13
Identities = 25/90 (27%), Positives = 36/90 (40%), Gaps = 11/90 (12%)
Query: 184 PPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHR 243
PP P P+ LST Y P SS +LA GPST ++ + +
Sbjct: 803 PPPAPRGRTPPNLLSTLQY---------PRPSSGTLASASPDWVGPSTRLRQQSSSS--K 851
Query: 244 ASDGKLRGRSKRSSDPSPAGDNEIERVFVW 273
+L+ R+ PSP N ++R W
Sbjct: 852 GDSPELKPRAVHKQGPSPVSPNALDRTAAW 881
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,149,671
Number of Sequences: 37866
Number of extensions: 1083014
Number of successful extensions: 4186
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 3916
Number of HSP's gapped (non-prelim): 347
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.