Guide to the Human Genome
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Search of human proteins with 26667227

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|26667227 eyes absent 2 isoform a [Homo sapiens]
         (538 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|26667227 eyes absent 2 isoform a [Homo sapiens]                   1103   0.0  
gi|26667240 eyes absent 2 isoform b [Homo sapiens]                   1103   0.0  
gi|26667235 eyes absent 2 isoform a [Homo sapiens]                   1103   0.0  
gi|26667232 eyes absent 2 isoform a [Homo sapiens]                   1103   0.0  
gi|26667230 eyes absent 2 isoform c [Homo sapiens]                   1042   0.0  
gi|19923100 eyes absent 1 isoform b [Homo sapiens]                    684   0.0  
gi|26667216 eyes absent 1 isoform b [Homo sapiens]                    684   0.0  
gi|26667222 eyes absent 1 isoform a [Homo sapiens]                    684   0.0  
gi|26667219 eyes absent 1 isoform c [Homo sapiens]                    625   e-179
gi|98991763 eyes absent 4 isoform b [Homo sapiens]                    607   e-173
gi|98991760 eyes absent 4 isoform a [Homo sapiens]                    607   e-173
gi|26667257 eyes absent 4 isoform d [Homo sapiens]                    588   e-168
gi|26667243 eyes absent 3 [Homo sapiens]                              459   e-129
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s...    53   8e-07
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    52   2e-06
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]           49   2e-05
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s...    46   1e-04
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...    46   1e-04
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap...    46   1e-04
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...    44   4e-04
gi|62122917 filaggrin family member 2 [Homo sapiens]                   42   0.002
gi|55770860 T-box 15 [Homo sapiens]                                    42   0.002
gi|122937492 SET domain containing 5 [Homo sapiens]                    40   0.005
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          39   0.016
gi|54607108 zinc finger, MIZ-type containing 2 isoform 1 [Homo s...    38   0.020
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho...    37   0.060
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom...    37   0.060
gi|39777614 SS18-like protein 1 [Homo sapiens]                         37   0.060
gi|46370086 transcription factor 12 isoform c [Homo sapiens]           36   0.078
gi|41281683 disabled homolog 2 interacting protein isoform 2 [Ho...    35   0.13 

>gi|26667227 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score = 1103 bits (2854), Expect = 0.0
 Identities = 538/538 (100%), Positives = 538/538 (100%)

Query: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
           MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60

Query: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
           QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG
Sbjct: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120

Query: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
           SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180

Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
           SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240

Query: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
           PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300

Query: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
           SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360

Query: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
           GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420

Query: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
           TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480

Query: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
           ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|26667240 eyes absent 2 isoform b [Homo sapiens]
          Length = 543

 Score = 1103 bits (2854), Expect = 0.0
 Identities = 538/538 (100%), Positives = 538/538 (100%)

Query: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
           MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 6   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 65

Query: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
           QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG
Sbjct: 66  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 125

Query: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
           SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 126 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 185

Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
           SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 186 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 245

Query: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
           PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 246 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 305

Query: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
           SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 306 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 365

Query: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
           GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 366 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 425

Query: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
           TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 426 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 485

Query: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
           ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 486 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 543


>gi|26667235 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score = 1103 bits (2854), Expect = 0.0
 Identities = 538/538 (100%), Positives = 538/538 (100%)

Query: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
           MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60

Query: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
           QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG
Sbjct: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120

Query: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
           SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180

Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
           SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240

Query: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
           PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300

Query: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
           SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360

Query: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
           GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420

Query: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
           TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480

Query: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
           ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|26667232 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score = 1103 bits (2854), Expect = 0.0
 Identities = 538/538 (100%), Positives = 538/538 (100%)

Query: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
           MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60

Query: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
           QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG
Sbjct: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120

Query: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
           SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180

Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
           SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240

Query: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
           PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300

Query: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
           SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360

Query: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
           GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420

Query: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
           TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480

Query: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
           ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|26667230 eyes absent 2 isoform c [Homo sapiens]
          Length = 514

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 514/538 (95%), Positives = 514/538 (95%), Gaps = 24/538 (4%)

Query: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60
           MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR
Sbjct: 1   MVELVISPSLTVNSDCLDKLKFNRADAAVWTLSDRQGITKSAPLRVSQLFSRSCPRVLPR 60

Query: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG 120
           QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS                      
Sbjct: 61  QPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS---------------------- 98

Query: 121 SSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
             FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS
Sbjct: 99  --FSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 156

Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 240
           SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR
Sbjct: 157 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDR 216

Query: 241 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 300
           PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT
Sbjct: 217 PHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTT 276

Query: 301 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 360
           SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP
Sbjct: 277 SVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAP 336

Query: 361 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 420
           GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL
Sbjct: 337 GANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEAL 396

Query: 421 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 480
           TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK
Sbjct: 397 TDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK 456

Query: 481 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
           ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Sbjct: 457 ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514


>gi|19923100 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score =  684 bits (1765), Expect = 0.0
 Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)

Query: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY      IKTE 
Sbjct: 91  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 150

Query: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158
            L+ S  PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 151 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 210

Query: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 211 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 270

Query: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 271 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 330

Query: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 331 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 390

Query: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 391 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 450

Query: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 451 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 510

Query: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 511 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 570

Query: 517 FWRISCHADLEALRHALELEYL 538
           FWRIS H+DL AL HALELEYL
Sbjct: 571 FWRISSHSDLMALHHALELEYL 592


>gi|26667216 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score =  684 bits (1765), Expect = 0.0
 Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)

Query: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY      IKTE 
Sbjct: 91  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 150

Query: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158
            L+ S  PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 151 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 210

Query: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 211 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 270

Query: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 271 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 330

Query: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 331 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 390

Query: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 391 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 450

Query: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 451 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 510

Query: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 511 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 570

Query: 517 FWRISCHADLEALRHALELEYL 538
           FWRIS H+DL AL HALELEYL
Sbjct: 571 FWRISSHSDLMALHHALELEYL 592


>gi|26667222 eyes absent 1 isoform a [Homo sapiens]
          Length = 559

 Score =  684 bits (1765), Expect = 0.0
 Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)

Query: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY      IKTE 
Sbjct: 58  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 117

Query: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158
            L+ S  PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 118 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 177

Query: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 178 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 237

Query: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 238 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 297

Query: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 298 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 357

Query: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 358 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 417

Query: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 418 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 477

Query: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 478 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 537

Query: 517 FWRISCHADLEALRHALELEYL 538
           FWRIS H+DL AL HALELEYL
Sbjct: 538 FWRISSHSDLMALHHALELEYL 559


>gi|26667219 eyes absent 1 isoform c [Homo sapiens]
          Length = 557

 Score =  625 bits (1613), Expect = e-179
 Identities = 315/497 (63%), Positives = 370/497 (74%), Gaps = 39/497 (7%)

Query: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHS 110
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY IKTE  L+ S
Sbjct: 91  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGIKTEGGLSQS 150

Query: 111 --PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGSVHQDY 163
             PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S  QDY
Sbjct: 151 QSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDY 210

Query: 164 PSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSSESLAG 221
           PSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+      
Sbjct: 211 PSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTA 270

Query: 222 EYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIII 281
           EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLDETII+
Sbjct: 271 EYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIV 330

Query: 282 FHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDN 341
           FHSLLTG++A+RYG+                              +CDQ+H+DDVSSDDN
Sbjct: 331 FHSLLTGSYANRYGR------------------------------ECDQVHIDDVSSDDN 360

Query: 342 GQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGL 401
           GQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKNNVGGL
Sbjct: 361 GQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGL 420

Query: 402 IGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLY 461
           +G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALAKVLLY
Sbjct: 421 LGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLY 480

Query: 462 GLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRIS 521
           GLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MPFWRIS
Sbjct: 481 GLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRIS 540

Query: 522 CHADLEALRHALELEYL 538
            H+DL AL HALELEYL
Sbjct: 541 SHSDLMALHHALELEYL 557


>gi|98991763 eyes absent 4 isoform b [Homo sapiens]
          Length = 616

 Score =  607 bits (1564), Expect = e-173
 Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)

Query: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 110 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 168

Query: 98  SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144
           +Y       +IKTE  L+   SP QSG LSY   FST   GQ+PY+YQM G++       
Sbjct: 169 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 228

Query: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 229 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 288

Query: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 289 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 341

Query: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 342 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 401

Query: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 402 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 461

Query: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 462 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 521

Query: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 522 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 581

Query: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 582 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616


>gi|98991760 eyes absent 4 isoform a [Homo sapiens]
          Length = 639

 Score =  607 bits (1564), Expect = e-173
 Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)

Query: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 133 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 191

Query: 98  SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144
           +Y       +IKTE  L+   SP QSG LSY   FST   GQ+PY+YQM G++       
Sbjct: 192 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 251

Query: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 252 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 311

Query: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 312 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 364

Query: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 365 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 424

Query: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 425 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 484

Query: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 485 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 544

Query: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 545 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 604

Query: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 605 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639


>gi|26667257 eyes absent 4 isoform d [Homo sapiens]
          Length = 639

 Score =  588 bits (1515), Expect = e-168
 Identities = 308/515 (59%), Positives = 374/515 (72%), Gaps = 24/515 (4%)

Query: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 133 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 191

Query: 98  SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144
           +Y       +IKTE  L+   SP QSG LSY   FST   GQ+PY+YQM G++       
Sbjct: 192 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 251

Query: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 252 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 311

Query: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 312 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 364

Query: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 365 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 424

Query: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 425 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 484

Query: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 485 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 544

Query: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERI+ RFG    YVVIGDG
Sbjct: 545 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDG 604

Query: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
            +EE  A +HNMPFWRIS H+DL AL  ALELEYL
Sbjct: 605 RDEEHAANQHNMPFWRISSHSDLLALHQALELEYL 639


>gi|26667243 eyes absent 3 [Homo sapiens]
          Length = 573

 Score =  459 bits (1180), Expect = e-129
 Identities = 254/516 (49%), Positives = 333/516 (64%), Gaps = 17/516 (3%)

Query: 38  ITKSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIP 97
           I +S+    SQ++S      +   P +  A  GQTQY   +QQ  PY  YP   Q YG+P
Sbjct: 60  IPRSSNDYTSQMYSAKPYAHILSVPVSETAYPGQTQYQT-LQQTQPYAVYPQATQTYGLP 118

Query: 98  SYS-----IKTEDSL--NHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT---GFYQGG 147
            +      +K E  L    SP Q   L+  +  +TS    + Y+Y +  ++         
Sbjct: 119 PFGALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQASSTNASLISTS 178

Query: 148 NGLGN--AAGFGSV-HQDYPSYPGFPQSQYPQYY-GSSYNPPYVPASSICPSPLSTSTYV 203
           + + N  AA   S+ +QDYP+Y    Q+QY   Y  SS+       S    + L+ +TY 
Sbjct: 179 STIANIPAAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSDAESTTLAATTYQ 238

Query: 204 LQEASHNVPNQSSESLA-GEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPA 262
            ++ S   P  +++ L+ G+ +T    S      DTD   R +    + R KR +D + +
Sbjct: 239 SEKPSVMAPAPAAQRLSSGDPSTSPSLSQTTPSKDTDDQSRKNMTS-KNRGKRKADATSS 297

Query: 263 GDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFF 322
            D+E+ERVF+WDLDETIIIFHSLLTG++A +YGKD T  +  GL MEEMIF +ADTHLFF
Sbjct: 298 QDSELERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFF 357

Query: 323 NDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAF 382
           NDLE+CDQ+HV+DV+SDDNGQDLS Y+FS DGF  S    +     GV GGVDWMRKLAF
Sbjct: 358 NDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAF 417

Query: 383 RYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCV 442
           RYR+V+E+Y+ +K+NVGGL+   ++E   +LRAE+E LTD WL  +LK+L LI SR NCV
Sbjct: 418 RYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCV 477

Query: 443 NVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGD 502
           NVL+TTTQL+PALAKVLLYGLG +FPIENIYSATK GKESCFERI+ RFG+K  YVVIGD
Sbjct: 478 NVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGD 537

Query: 503 GVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538
           G +EE  AK+HNMPFWRI+ H DL +L  ALEL++L
Sbjct: 538 GRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL 573


>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
           sapiens]
          Length = 600

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 62/224 (27%), Positives = 85/224 (37%), Gaps = 27/224 (12%)

Query: 67  AAYGQTQYSAGI-QQATPYT------AYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSY 119
           A YGQT Y+    Q  T YT      AY  P Q YG  +Y   T          +   +Y
Sbjct: 59  ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 120 GS-----SFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQY 174
           G+     ++   P   +P +Y     T + Q      N  G  S +    SY    QS Y
Sbjct: 119 GTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYG--QQSSY 176

Query: 175 PQYYGSSYNPPYVPASSICPSPLS--TSTYVLQE-------ASHNVPNQSSESLA--GEY 223
            Q   +SY PP   + S  PS  S  +S+Y  Q        +S  V  Q S   +  GE 
Sbjct: 177 GQQPPTSY-PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGEN 235

Query: 224 NTHNGPSTPAK-EGDTDRPHRASDGKLRGRSKRSSDPSPAGDNE 266
            + +GP    +  G  DR   +  G+  GR    S     G N+
Sbjct: 236 RSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNK 279


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 54/169 (31%), Positives = 73/169 (43%), Gaps = 29/169 (17%)

Query: 79  QQATP-YTAYPPP---------AQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPT 128
           QQAT  Y AYP           +Q YG  SYS  ++ +     GQS + SYG S +T   
Sbjct: 8   QQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYG 67

Query: 129 GQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQ----YYG----- 179
            QS  T Q +G+TG      G G++    S +    SYPG+ Q   P      YG     
Sbjct: 68  TQS--TPQGYGSTG------GYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQS 119

Query: 180 SSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNG 228
           SSY  P   + S  PS         Q+ S+N P    +    +YN+ +G
Sbjct: 120 SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQ--NQYNSSSG 166



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 42/124 (33%), Positives = 49/124 (39%), Gaps = 16/124 (12%)

Query: 63  STAMAAYGQTQYSA-GIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGS 121
           ST  + YGQ+ YS+ G  Q T Y     P Q YG          +  +   QS   SYG 
Sbjct: 44  STDTSGYGQSSYSSYGQSQNTGYGTQSTP-QGYG---------STGGYGSSQSSQSSYGQ 93

Query: 122 SFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSS 181
             S    GQ P      G+ G     +  G     GS  Q  PSY G  QS   Q    S
Sbjct: 94  QSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQS-GSYSQQ-PSYGGQQQSYGQQ---QS 148

Query: 182 YNPP 185
           YNPP
Sbjct: 149 YNPP 152


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 61/206 (29%), Positives = 86/206 (41%), Gaps = 36/206 (17%)

Query: 68  AYGQTQYSAGIQQATPYTAYPPP-AQAYGIPSYSI----KTEDSLNHSPGQSGFLSYGSS 122
           +YGQ   S G QQ+  Y+ Y  P +Q YG  S S     +T DS ++    SG+ SYG S
Sbjct: 6   SYGQ---SGGEQQS--YSTYGNPGSQGYGQASQSYSGYGQTTDS-SYGQNYSGYSSYGQS 59

Query: 123 FSTSPTG-----QSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQ--DYPSYPGF-PQSQY 174
           +S S  G     QS Y+ Q +   G  Q     G+  G    +   DY     +  QS Y
Sbjct: 60  YSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGY 119

Query: 175 PQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTH--NGPSTP 232
            Q+ G SY+                S Y  Q  S++   QS  S    Y+ H  +     
Sbjct: 120 DQHQG-SYD--------------EQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDV 164

Query: 233 AKEGDTDRPHRASDGKLRGRSKRSSD 258
           ++ G+ +R +  S G  RGR     D
Sbjct: 165 SRYGEDNRGYGGSQGGGRGRGGYDKD 190


>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
           sapiens]
          Length = 354

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 54/200 (27%), Positives = 73/200 (36%), Gaps = 43/200 (21%)

Query: 67  AAYGQTQYSAGI-QQATPYT------AYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSY 119
           A YGQT Y+    Q  T YT      AY  P Q YG  +Y   T          +   +Y
Sbjct: 59  ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 120 GSSFSTSPTGQSP---------------YTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYP 164
           G+  +    GQ P                T Q   +TG Y        + G+G  +  YP
Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYN-----QPSLGYGQSNYSYP 173

Query: 165 ----SYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPN----QSS 216
               SYP  P +  P Y  +SY       SS  P+    S+Y  Q+ ++  P+    QSS
Sbjct: 174 QVPGSYPMQPVTAPPSYPPTSY-------SSTQPTSYDQSSY-SQQNTYGQPSSYGQQSS 225

Query: 217 ESLAGEYNTHNGPSTPAKEG 236
                 Y      S P + G
Sbjct: 226 YGQQSSYGQQPPTSYPPQTG 245



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 15/115 (13%)

Query: 55  PRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIP-SYSIKTEDSLNHSPGQ 113
           P   P QP TA  +Y  T YS+    +   ++Y      YG P SY  ++      S GQ
Sbjct: 176 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQ 234

Query: 114 SGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
               SY     T    Q+P  Y         Q  +  G  + F    QD+PS  G
Sbjct: 235 QPPTSYPP--QTGSYSQAPSQYS--------QQSSSYGQQSSF---RQDHPSSMG 276


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
           sapiens]
          Length = 655

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 54/200 (27%), Positives = 73/200 (36%), Gaps = 43/200 (21%)

Query: 67  AAYGQTQYSAGI-QQATPYT------AYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSY 119
           A YGQT Y+    Q  T YT      AY  P Q YG  +Y   T          +   +Y
Sbjct: 59  ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 120 GSSFSTSPTGQSP---------------YTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYP 164
           G+  +    GQ P                T Q   +TG Y        + G+G  +  YP
Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYN-----QPSLGYGQSNYSYP 173

Query: 165 ----SYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPN----QSS 216
               SYP  P +  P Y  +SY       SS  P+    S+Y  Q+ ++  P+    QSS
Sbjct: 174 QVPGSYPMQPVTAPPSYPPTSY-------SSTQPTSYDQSSY-SQQNTYGQPSSYGQQSS 225

Query: 217 ESLAGEYNTHNGPSTPAKEG 236
                 Y      S P + G
Sbjct: 226 YGQQSSYGQQPPTSYPPQTG 245



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 15/115 (13%)

Query: 55  PRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIP-SYSIKTEDSLNHSPGQ 113
           P   P QP TA  +Y  T YS+    +   ++Y      YG P SY  ++      S GQ
Sbjct: 176 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQ 234

Query: 114 SGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
               SY     T    Q+P  Y         Q  +  G  + F    QD+PS  G
Sbjct: 235 QPPTSYPP--QTGSYSQAPSQYS--------QQSSSYGQQSSF---RQDHPSSMG 276


>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
           sapiens]
          Length = 656

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 54/200 (27%), Positives = 73/200 (36%), Gaps = 43/200 (21%)

Query: 67  AAYGQTQYSAGI-QQATPYT------AYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSY 119
           A YGQT Y+    Q  T YT      AY  P Q YG  +Y   T          +   +Y
Sbjct: 59  ATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118

Query: 120 GSSFSTSPTGQSP---------------YTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYP 164
           G+  +    GQ P                T Q   +TG Y        + G+G  +  YP
Sbjct: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYN-----QPSLGYGQSNYSYP 173

Query: 165 ----SYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPN----QSS 216
               SYP  P +  P Y  +SY       SS  P+    S+Y  Q+ ++  P+    QSS
Sbjct: 174 QVPGSYPMQPVTAPPSYPPTSY-------SSTQPTSYDQSSY-SQQNTYGQPSSYGQQSS 225

Query: 217 ESLAGEYNTHNGPSTPAKEG 236
                 Y      S P + G
Sbjct: 226 YGQQSSYGQQPPTSYPPQTG 245



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 15/115 (13%)

Query: 55  PRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIP-SYSIKTEDSLNHSPGQ 113
           P   P QP TA  +Y  T YS+    +   ++Y      YG P SY  ++      S GQ
Sbjct: 176 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQ 234

Query: 114 SGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
               SY     T    Q+P  Y         Q  +  G  + F    QD+PS  G
Sbjct: 235 QPPTSYPP--QTGSYSQAPSQYS--------QQSSSYGQQSSF---RQDHPSSMG 276


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 54/206 (26%), Positives = 74/206 (35%), Gaps = 49/206 (23%)

Query: 67  AAYGQTQYSAGIQQ-------ATPYT------AYPPPAQAYGIPSYSIKTEDSLNHSPGQ 113
           A YGQT Y+    Q       +T YT      AY  P Q YG  +Y   T          
Sbjct: 59  ATYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASY 118

Query: 114 SGFLSYGSSFSTSPTGQSP---------------YTYQMHGTTGFYQGGNGLGNAAGFGS 158
           +   +YG+  +    GQ P                T Q   +TG Y        + G+G 
Sbjct: 119 AAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYN-----QPSLGYGQ 173

Query: 159 VHQDYP----SYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPN- 213
            +  YP    SYP  P +  P Y  +SY       SS  P+    S+Y  Q+ ++  P+ 
Sbjct: 174 SNYSYPQVPGSYPMQPVTAPPSYPPTSY-------SSTQPTSYDQSSY-SQQNTYGQPSS 225

Query: 214 ---QSSESLAGEYNTHNGPSTPAKEG 236
              QSS      Y      S P + G
Sbjct: 226 YGQQSSYGQQSSYGQQPPTSYPPQTG 251



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 15/115 (13%)

Query: 55  PRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIP-SYSIKTEDSLNHSPGQ 113
           P   P QP TA  +Y  T YS+    +   ++Y      YG P SY  ++      S GQ
Sbjct: 182 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQ 240

Query: 114 SGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
               SY     T    Q+P  Y         Q  +  G  + F    QD+PS  G
Sbjct: 241 QPPTSYPP--QTGSYSQAPSQYS--------QQSSSYGQQSSF---RQDHPSSMG 282


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 19/199 (9%)

Query: 70  GQTQYSAGIQQATPYTAYPPPA-QAYGIPSYSIKTEDSL--NHSPGQSGFLSYGSSFSTS 126
           G  QY +G  Q++ +  +   + Q+ G   +  ++  S    HS G S    YG   S  
Sbjct: 579 GFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQ 638

Query: 127 PTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQ-------SQYPQY-Y 178
            +G   +      +TGF Q G+G G ++GFG          GF Q       S Y Q+ +
Sbjct: 639 TSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGF 698

Query: 179 GSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDT 238
           GSS +  Y    S   S   TS +      H + +  S S  G++ + +G S+   +  +
Sbjct: 699 GSSQSSGYGQHGS---SSGQTSGF----GQHELSSGQSSSF-GQHGSGSGQSSGFGQHGS 750

Query: 239 DRPHRASDGKLRGRSKRSS 257
                +  G+   RS +SS
Sbjct: 751 GSGQSSGFGQHESRSGQSS 769



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 44/157 (28%), Positives = 62/157 (39%), Gaps = 16/157 (10%)

Query: 109 HSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
           HS G S    YG   S   +G   +      +TGF Q G+G G +AGFG          G
Sbjct: 773 HSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSG 832

Query: 169 F-------PQSQYPQY-YGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLA 220
           F        QS Y Q+  GSS +  Y    S   S   TS +    +S         S  
Sbjct: 833 FGQHESRSHQSSYGQHGSGSSQSSGYGQHGS---SSGQTSGFGQHRSS-----SGQYSGF 884

Query: 221 GEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSS 257
           G++ + +G S+   +  T     +  G+   RS +SS
Sbjct: 885 GQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSS 921



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 32/118 (27%), Positives = 50/118 (42%), Gaps = 9/118 (7%)

Query: 70  GQTQYSAGIQQATPYTAYPPPA-QAYGIPSYSIKTEDSL--NHSPGQSGFLSYGSSFSTS 126
           G  QY +G  Q+  +  +   + Q+ G   +  ++  S    H  G S    YG   S+S
Sbjct: 806 GFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSS 865

Query: 127 PTGQSPYTYQMHGTTGFYQG----GNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGS 180
             GQ+    Q   ++G Y G    G+G G ++GFG        Y GF Q +   +  S
Sbjct: 866 --GQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSS 921



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 44/169 (26%), Positives = 70/169 (41%), Gaps = 9/169 (5%)

Query: 70   GQTQYSAGIQQATPYTAYPPPA-QAYGIPSYSIKTEDSL--NHSPGQSGFLSYGSSFSTS 126
            G  Q+ +G  Q++ +  +   + Q+ G   Y  ++  S    H  G S    YG   S S
Sbjct: 1037 GFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNS 1096

Query: 127  --PTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNP 184
               +G   +      ++GF Q G+G G ++GFG          GF Q +Y +   SSY  
Sbjct: 1097 GQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEY-RSGQSSYGQ 1155

Query: 185  PYVPA--SSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPST 231
                +  SS C    S S        H V    + S +G++ + +G ST
Sbjct: 1156 HGTGSSQSSGCGQHESGSGPTTSFGQH-VSGSDNFSSSGQHISDSGQST 1203



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 8/86 (9%)

Query: 109 HSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPG 168
           H  G S    YG   S   +G   +      +TGF Q G+G G ++GFG          G
Sbjct: 546 HGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSG 605

Query: 169 F-------PQSQYPQY-YGSSYNPPY 186
           F        QS Y Q+  GSS +  Y
Sbjct: 606 FGQHESRSGQSSYGQHSSGSSQSSGY 631



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 53/218 (24%), Positives = 87/218 (39%), Gaps = 27/218 (12%)

Query: 70   GQTQYSAGIQQATPYTAYPPPAQAY-GIPSYSIKTEDSL--NHSPGQSGFLSYGSSFSTS 126
            G  Q+ +G  Q++ +  +   +  Y G   +  ++  S    H  G S    YG   S+S
Sbjct: 883  GFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSS 942

Query: 127  PTGQSPYTYQMHGT-----TGFYQGGNGLGNAAGFGSVHQDYPSYPGF-------PQSQY 174
              GQ+ + +  H +     +GF Q G+G G ++GFG          GF        QS Y
Sbjct: 943  --GQT-FGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNY 999

Query: 175  PQY-YGSSYNPPYVPASSICPSPL------STSTYVLQEASHNVPNQSSESLAGEYNTHN 227
             Q+  GSS +  Y    S            S+S        H   +  S    G++ T +
Sbjct: 1000 GQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGF-GQHGTGS 1058

Query: 228  GPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDN 265
            G S+   + ++ R  ++S G+    S +SS     G N
Sbjct: 1059 GQSSGFGQYES-RSRQSSYGQHGSGSSQSSGYGQHGSN 1095



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 6/62 (9%)

Query: 113 QSGFLSYGSSFSTSPTGQSPYTYQMHG---TTGFYQGGNGLGNAAGFGSVHQDYPSYPGF 169
           +SG  SYG   S S        Y  HG   T+GF Q G+G   + GFG          GF
Sbjct: 764 RSGQSSYGQHSSGSSQSSG---YGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGF 820

Query: 170 PQ 171
            Q
Sbjct: 821 GQ 822



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 19/54 (35%), Positives = 21/54 (38%)

Query: 118 SYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQ 171
           SYG   S S        Y    T+GF Q G G G + GFG          GF Q
Sbjct: 542 SYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQ 595



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 5/49 (10%)

Query: 128 TGQSPYTYQMHG-----TTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQ 171
           T      Y  HG     T+GF Q G+G G ++GFG          GF Q
Sbjct: 459 TSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQ 507


>gi|55770860 T-box 15 [Homo sapiens]
          Length = 496

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 57/217 (26%), Positives = 81/217 (37%), Gaps = 31/217 (14%)

Query: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQAT-PYTAYPP---PAQAYGIPSYSIKTEDS 106
           +RS    L   P  + + Y + Q  +G   AT P   + P   P+   GIP     T  S
Sbjct: 297 ARSNMAALQSYPGLSDSGYNRLQ--SGTTSATQPSETFMPQRTPSLISGIP-----TPPS 349

Query: 107 LNHSPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAG---FGSVHQDY 163
           L   PG S   +YG    + PT Q  Y           Q GN   +++    FG  H   
Sbjct: 350 L---PGNSKMEAYGGQLGSFPTSQFQYV---------MQAGNAASSSSSPHMFGGSHMQQ 397

Query: 164 PSYPGFPQSQYPQYYGSSYNPPYVPASSICPSPLST--STYVLQEASHNVPNQSSESLAG 221
            SY  F        YG  YN P  P  +  P  LS   ST +    S+    +     +G
Sbjct: 398 SSYNAFSLHNPYNLYG--YNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPSG 455

Query: 222 -EYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSS 257
            E++ H    +P  +  T+       G + G S + S
Sbjct: 456 MEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMS 492


>gi|122937492 SET domain containing 5 [Homo sapiens]
          Length = 1442

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 38/174 (21%), Positives = 65/174 (37%), Gaps = 14/174 (8%)

Query: 79   QQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTSPTGQ---SPYTY 135
            Q ++P+  +P  +  Y   + +++  +  +H   +S   S   S    P      +P+T 
Sbjct: 1257 QSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFT- 1315

Query: 136  QMHGTTGFYQGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICPS 195
               GT G++      GN+ G     +  PS    P  Q     G S +P     S     
Sbjct: 1316 ---GTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQ-----GPSDSPTSDSVSQSSTG 1367

Query: 196  PLSTSTYVLQEASHNVPNQSSESL--AGEYNTHNGPSTPAKEGDTDRPHRASDG 247
             LS++++     S    +  + SL  AG+   +      A       PHR S G
Sbjct: 1368 TLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRGSGG 1421


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 60/250 (24%), Positives = 87/250 (34%), Gaps = 29/250 (11%)

Query: 40   KSAPLRVSQLFSRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAY----G 95
            K+ P   S     S P    + P   +      Q   G    +   + P PA        
Sbjct: 1129 KNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGD 1188

Query: 96   IPSYSIKTEDSLNHSPGQSGFLSYGSSFSTS----------PTGQSPYTYQMHGTTGFYQ 145
              S + K E ++  +P  SG  S   SFS S          PT  S +T     T    +
Sbjct: 1189 KASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKE 1248

Query: 146  GGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYN-PPYVPASSICPSPLSTSTYVL 204
                   ++G GS     PSY   P+S  P    S+ N  P  PA+S    P++ S   L
Sbjct: 1249 SSQPDAFSSGGGSK----PSYEAIPESSPPSGITSASNTTPGEPAAS-SSRPVAPSGTAL 1303

Query: 205  QEASHNVPNQSSE--------SLAGE-YNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKR 255
               S  +    S+        SLAGE   + +G      +  T   ++AS   L      
Sbjct: 1304 STTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPT 1363

Query: 256  SSDPSPAGDN 265
             +   P+G N
Sbjct: 1364 KTSGVPSGFN 1373


>gi|54607108 zinc finger, MIZ-type containing 2 isoform 1 [Homo
           sapiens]
          Length = 920

 Score = 38.1 bits (87), Expect = 0.020
 Identities = 49/160 (30%), Positives = 63/160 (39%), Gaps = 44/160 (27%)

Query: 68  AYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYG------S 121
           A G T   AG  Q  P   YP P QA  +P   +K   S  + PGQ  +L  G      +
Sbjct: 234 AAGMTPLYAG--QRLPQHGYPGPPQAQPLPRQGVKRTYSEVY-PGQQ-YLQGGQYAPSTA 289

Query: 122 SFSTSPTGQSPY---TYQMH---------------GTTGFY----QGGNGLGNAAGFGSV 159
            F+ SP GQ P    +Y  H               G TG +    +  NG G +   GSV
Sbjct: 290 QFAPSP-GQPPAPSPSYPGHRLPLQQGMTQSLSVPGPTGLHYKPTEQFNGQGASFNGGSV 348

Query: 160 HQDYP-------SYPGFPQSQYPQYYGSSYNPPYVPASSI 192
               P       S PG+P S  P     +  PP  P+SS+
Sbjct: 349 SYSQPGLSGPTRSIPGYPSSPLP----GNPTPPMTPSSSV 384


>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
           sapiens]
          Length = 898

 Score = 36.6 bits (83), Expect = 0.060
 Identities = 41/158 (25%), Positives = 60/158 (37%), Gaps = 11/158 (6%)

Query: 114 SGFLSYGSSFSTSPTGQSP-YTYQMHGTTGFYQGGNGLGNAAGFGSVHQ--DY-----PS 165
           +G+ SYG   +++  G S  Y+   H       GG G G ++G+GS +Q  +Y     P 
Sbjct: 674 AGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPK 733

Query: 166 YPGFPQ---SQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGE 222
           + G  Q    Q    YGS Y        S   SP S       +       Q S S +  
Sbjct: 734 HAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNS 793

Query: 223 YNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPS 260
           YN+  G        ++   +  S G+  G S  S   S
Sbjct: 794 YNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGAS 831


>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
           sapiens]
          Length = 894

 Score = 36.6 bits (83), Expect = 0.060
 Identities = 41/158 (25%), Positives = 60/158 (37%), Gaps = 11/158 (6%)

Query: 114 SGFLSYGSSFSTSPTGQSP-YTYQMHGTTGFYQGGNGLGNAAGFGSVHQ--DY-----PS 165
           +G+ SYG   +++  G S  Y+   H       GG G G ++G+GS +Q  +Y     P 
Sbjct: 670 AGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPK 729

Query: 166 YPGFPQ---SQYPQYYGSSYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGE 222
           + G  Q    Q    YGS Y        S   SP S       +       Q S S +  
Sbjct: 730 HAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNS 789

Query: 223 YNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPS 260
           YN+  G        ++   +  S G+  G S  S   S
Sbjct: 790 YNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGAS 827


>gi|39777614 SS18-like protein 1 [Homo sapiens]
          Length = 396

 Score = 36.6 bits (83), Expect = 0.060
 Identities = 36/148 (24%), Positives = 52/148 (35%), Gaps = 22/148 (14%)

Query: 59  PRQPSTAMAAYGQTQY-------SAGIQQATPYTAYPP-------PAQAYGIPSYSIKTE 104
           P Q  ++    GQ +Y       S G  +      YP           +Y   SY    E
Sbjct: 237 PSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFE 296

Query: 105 DSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTTGFYQGGNGLGNAAGFGSVHQD 162
           +S  H    G S +    + +      Q  Y+ Q + +   Y G        G+GS    
Sbjct: 297 ESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPG-----QQQGYGSAQGA 351

Query: 163 YPSYPGFPQSQYPQYYGSSYNPPYVPAS 190
              YPG+ Q Q  Q YGS   P   P++
Sbjct: 352 PSQYPGYQQGQ-GQQYGSYRAPQTAPSA 378


>gi|46370086 transcription factor 12 isoform c [Homo sapiens]
          Length = 512

 Score = 36.2 bits (82), Expect = 0.078
 Identities = 43/170 (25%), Positives = 60/170 (35%), Gaps = 31/170 (18%)

Query: 84  YTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGSSFSTS--PTGQSPYTYQM---- 137
           Y AYP P        Y    +     SP    F     S+ +   PT     T+ M    
Sbjct: 2   YCAYPVPGMGSNSLMYYYNGKTVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGT 61

Query: 138 HGTTGFYQGGNGLGN----------------AAGFGSVHQ-DYPSYPGFPQSQYPQYYGS 180
           H ++  +   NG+                  ++ +G++H  D  SYP  P S  P    +
Sbjct: 62  HNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYP--PHSVSP----T 115

Query: 181 SYNPPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPS 230
             N    P SS      S+S YV   ASH  P   S+S+ G      G S
Sbjct: 116 DINTSLPPMSSFHRGSTSSSPYVA--ASHTPPINGSDSILGTRGNAAGSS 163


>gi|41281683 disabled homolog 2 interacting protein isoform 2 [Homo
           sapiens]
          Length = 1065

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 25/90 (27%), Positives = 36/90 (40%), Gaps = 11/90 (12%)

Query: 184 PPYVPASSICPSPLSTSTYVLQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHR 243
           PP  P     P+ LST  Y         P  SS +LA       GPST  ++  +    +
Sbjct: 803 PPPAPRGRTPPNLLSTLQY---------PRPSSGTLASASPDWVGPSTRLRQQSSSS--K 851

Query: 244 ASDGKLRGRSKRSSDPSPAGDNEIERVFVW 273
               +L+ R+     PSP   N ++R   W
Sbjct: 852 GDSPELKPRAVHKQGPSPVSPNALDRTAAW 881


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,149,671
Number of Sequences: 37866
Number of extensions: 1083014
Number of successful extensions: 4186
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 3916
Number of HSP's gapped (non-prelim): 347
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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