Search of human proteins with 26051266

Search of human proteins with 26051266

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|26051266 potassium voltage-gated channel KQT-like protein 2
isoform d [Homo sapiens]
         (841 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|26051266 potassium voltage-gated channel KQT-like protein 2 i...  1712   0.0  
gi|26051262 potassium voltage-gated channel KQT-like protein 2 i...  1699   0.0  
gi|26051264 potassium voltage-gated channel KQT-like protein 2 i...  1692   0.0  
gi|26051260 potassium voltage-gated channel KQT-like protein 2 i...  1672   0.0  
gi|26051268 potassium voltage-gated channel KQT-like protein 2 i...   759   0.0  
gi|236462079 potassium voltage-gated channel, KQT-like subfamily...   672   0.0  
gi|236461942 potassium voltage-gated channel, KQT-like subfamily...   670   0.0  
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,...   669   0.0  
gi|236461719 potassium voltage-gated channel, KQT-like subfamily...   667   0.0  
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i...   662   0.0  
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H...   662   0.0  
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i...   659   0.0  
gi|236462242 potassium voltage-gated channel, KQT-like subfamily...   474   e-133
gi|32479527 potassium voltage-gated channel, KQT-like subfamily,...   395   e-110
gi|32479525 potassium voltage-gated channel, KQT-like subfamily,...   370   e-102
gi|21217561 Shaw-related voltage-gated potassium channel protein...   104   3e-22
gi|21217563 Shaw-related voltage-gated potassium channel protein...   104   3e-22
gi|24497458 Shaw-related voltage-gated potassium channel protein...   104   3e-22
gi|119395748 potassium voltage-gated channel subfamily A member ...    95   3e-19
gi|88758565 potassium voltage-gated channel, shaker-related subf...    94   5e-19
gi|4504817 potassium voltage-gated channel, shaker-related subfa...    94   5e-19
gi|4826784 potassium voltage-gated channel, Shab-related subfami...    92   2e-18
gi|163792201 Shaw-related voltage-gated potassium channel protei...    92   2e-18
gi|27436974 potassium voltage-gated channel, Shab-related subfam...    92   3e-18
gi|4826786 Shaw-related voltage-gated potassium channel protein ...    92   3e-18
gi|27436984 potassium voltage-gated channel, Shal-related subfam...    91   4e-18
gi|88758576 Shaw-related voltage-gated potassium channel protein...    90   1e-17
gi|24497462 Shaw-related voltage-gated potassium channel protein...    90   1e-17
gi|24497464 Shaw-related voltage-gated potassium channel protein...    90   1e-17
gi|4504821 potassium voltage-gated channel, shaker-related subfa...    89   2e-17

>gi|26051266 potassium voltage-gated channel KQT-like protein 2
           isoform d [Homo sapiens]
          Length = 841

 Score = 1712 bits (4435), Expect = 0.0
 Identities = 841/841 (100%), Positives = 841/841 (100%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSPRGV 420
           QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSPRGV
Sbjct: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSPRGV 420

Query: 421 AAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEAS 480
           AAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEAS
Sbjct: 421 AAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEAS 480

Query: 481 LPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQY 540
           LPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQY
Sbjct: 481 LPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQY 540

Query: 541 SAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVL 600
           SAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVL
Sbjct: 541 SAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVL 600

Query: 601 SMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVR 660
           SMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVR
Sbjct: 601 SMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVR 660

Query: 661 SSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGSLVRIPPPPAHERS 720
           SSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGSLVRIPPPPAHERS
Sbjct: 661 SSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGSLVRIPPPPAHERS 720

Query: 721 LSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSK 780
           LSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSK
Sbjct: 721 LSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSK 780

Query: 781 ENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWAGPR 840
           ENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWAGPR
Sbjct: 781 ENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWAGPR 840

Query: 841 K 841
           K
Sbjct: 841 K 841


>gi|26051262 potassium voltage-gated channel KQT-like protein 2
           isoform b [Homo sapiens]
          Length = 854

 Score = 1699 bits (4400), Expect = 0.0
 Identities = 841/854 (98%), Positives = 841/854 (98%), Gaps = 13/854 (1%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP----- 415
           QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP     
Sbjct: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS 420

Query: 416 -------SPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 468
                  SPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI
Sbjct: 421 LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 480

Query: 469 KGAASRQNS-EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 527
           KGAASRQNS EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES
Sbjct: 481 KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 540

Query: 528 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 587
           LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS
Sbjct: 541 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 600

Query: 588 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 647
           MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE
Sbjct: 601 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 660

Query: 648 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 707
           HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS
Sbjct: 661 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 720

Query: 708 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 767
           LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL
Sbjct: 721 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 780

Query: 768 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 827
           ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG
Sbjct: 781 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 840

Query: 828 EGPFGDVGWAGPRK 841
           EGPFGDVGWAGPRK
Sbjct: 841 EGPFGDVGWAGPRK 854


>gi|26051264 potassium voltage-gated channel KQT-like protein 2
           isoform a [Homo sapiens]
          Length = 872

 Score = 1692 bits (4382), Expect = 0.0
 Identities = 841/872 (96%), Positives = 841/872 (96%), Gaps = 31/872 (3%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP----- 415
           QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP     
Sbjct: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSKGSP 420

Query: 416 -------------------------SPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKV 450
                                    SPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKV
Sbjct: 421 CRGPLCGCCPGRSSQKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKV 480

Query: 451 PKSWSFGDRSRARQAFRIKGAASRQNS-EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSI 509
           PKSWSFGDRSRARQAFRIKGAASRQNS EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSI
Sbjct: 481 PKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSI 540

Query: 510 RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAIT 569
           RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAIT
Sbjct: 541 RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAIT 600

Query: 570 DKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFG 629
           DKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFG
Sbjct: 601 DKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFG 660

Query: 630 AKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQP 689
           AKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQP
Sbjct: 661 AKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQP 720

Query: 690 QSHPRQGHGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGN 749
           QSHPRQGHGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGN
Sbjct: 721 QSHPRQGHGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGN 780

Query: 750 LRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESD 809
           LRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESD
Sbjct: 781 LRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESD 840

Query: 810 TDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK 841
           TDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK
Sbjct: 841 TDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK 872


>gi|26051260 potassium voltage-gated channel KQT-like protein 2
           isoform c [Homo sapiens]
          Length = 844

 Score = 1672 bits (4330), Expect = 0.0
 Identities = 831/854 (97%), Positives = 831/854 (97%), Gaps = 23/854 (2%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP----- 415
           QYYERTVTVPMY          RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP     
Sbjct: 361 QYYERTVTVPMY----------RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS 410

Query: 416 -------SPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 468
                  SPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI
Sbjct: 411 LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 470

Query: 469 KGAASRQNS-EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 527
           KGAASRQNS EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES
Sbjct: 471 KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 530

Query: 528 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 587
           LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS
Sbjct: 531 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 590

Query: 588 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 647
           MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE
Sbjct: 591 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 650

Query: 648 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 707
           HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS
Sbjct: 651 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 710

Query: 708 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 767
           LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL
Sbjct: 711 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 770

Query: 768 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 827
           ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG
Sbjct: 771 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 830

Query: 828 EGPFGDVGWAGPRK 841
           EGPFGDVGWAGPRK
Sbjct: 831 EGPFGDVGWAGPRK 844


>gi|26051268 potassium voltage-gated channel KQT-like protein 2
           isoform e [Homo sapiens]
          Length = 393

 Score =  759 bits (1959), Expect = 0.0
 Identities = 372/372 (100%), Positives = 372/372 (100%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMY 372
           QYYERTVTVPMY
Sbjct: 361 QYYERTVTVPMY 372


>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 4 [Homo sapiens]
          Length = 951

 Score =  672 bits (1734), Expect = 0.0
 Identities = 371/668 (55%), Positives = 454/668 (67%), Gaps = 34/668 (5%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTV--PMYSSQ 375
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +    P    Q
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTKKEQ 410

Query: 376 TQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSPRGVAAKGKGSPQAQTVRR 435
            +   +           +  + K    L+F++        SPRG + K + +      RR
Sbjct: 411 GEASSSKFCSNKQKLFRMYTSRKQSQKLSFKE---RVRMASPRGQSIKSRQASVGD--RR 465

Query: 436 SPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQ--NSEASLPGEDIVDDKSCP 493
           SPS D + E SP+KV KSWSF DR+R R + R+K +  +   +++ +L  +D+ D+K C 
Sbjct: 466 SPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQ 525

Query: 494 CEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKS 553
           C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKS
Sbjct: 526 CDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKS 585

Query: 554 LQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNI 612
           LQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++I
Sbjct: 586 LQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDI 645

Query: 613 YMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSST 665
           Y Q  R G       A F     E E    Y SP DS++        GC+ +   ++ S 
Sbjct: 646 YQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISR 705

Query: 666 GQKNFSAP 673
           G +    P
Sbjct: 706 GLQFILTP 713


>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 3 [Homo sapiens]
          Length = 942

 Score =  670 bits (1729), Expect = 0.0
 Identities = 371/666 (55%), Positives = 456/666 (68%), Gaps = 39/666 (5%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +      S T 
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHT---CSPTN 407

Query: 378 TYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSPRGVAAKGKGSPQAQTVRRSP 437
            + +++         +  + K    L+F++        SPRG + K + +      RRSP
Sbjct: 408 KFCSNK----QKLFRMYTSRKQSQKLSFKE---RVRMASPRGQSIKSRQASVGD--RRSP 458

Query: 438 SADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQ--NSEASLPGEDIVDDKSCPCE 495
           S D + E SP+KV KSWSF DR+R R + R+K +  +   +++ +L  +D+ D+K C C+
Sbjct: 459 STDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCD 518

Query: 496 FVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQ 555
              EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ
Sbjct: 519 VSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQ 578

Query: 556 SRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYM 614
           +RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++IY 
Sbjct: 579 TRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQ 638

Query: 615 Q--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSSTGQ 667
           Q  R G       A F     E E    Y SP DS++        GC+ +   ++ S G 
Sbjct: 639 QVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGL 698

Query: 668 KNFSAP 673
           +    P
Sbjct: 699 QFILTP 704


>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 1 [Homo sapiens]
          Length = 932

 Score =  669 bits (1725), Expect = 0.0
 Identities = 371/668 (55%), Positives = 453/668 (67%), Gaps = 53/668 (7%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTV--PMYSSQ 375
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +    P    Q
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTKKEQ 410

Query: 376 TQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSPRGVAAKGKGSPQAQTVRR 435
            +   + +L           + K +  +A           SPRG + K + +      RR
Sbjct: 411 GEASSSQKL-----------SFKERVRMA-----------SPRGQSIKSRQASVGD--RR 446

Query: 436 SPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQ--NSEASLPGEDIVDDKSCP 493
           SPS D + E SP+KV KSWSF DR+R R + R+K +  +   +++ +L  +D+ D+K C 
Sbjct: 447 SPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQ 506

Query: 494 CEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKS 553
           C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKS
Sbjct: 507 CDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKS 566

Query: 554 LQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNI 612
           LQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++I
Sbjct: 567 LQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDI 626

Query: 613 YMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSST 665
           Y Q  R G       A F     E E    Y SP DS++        GC+ +   ++ S 
Sbjct: 627 YQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISR 686

Query: 666 GQKNFSAP 673
           G +    P
Sbjct: 687 GLQFILTP 694


>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 2 [Homo sapiens]
          Length = 923

 Score =  667 bits (1720), Expect = 0.0
 Identities = 372/666 (55%), Positives = 451/666 (67%), Gaps = 58/666 (8%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +             E++V++  +    +
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAAD-------------EKSVSIATWKPHLK 398

Query: 378 TYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSPRGVAAKGKGSPQAQTVRRSP 437
              A     P NQ     + K +  +A           SPRG + K + +      RRSP
Sbjct: 399 ---ALHTCSPTNQ---KLSFKERVRMA-----------SPRGQSIKSRQASVGD--RRSP 439

Query: 438 SADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQ--NSEASLPGEDIVDDKSCPCE 495
           S D + E SP+KV KSWSF DR+R R + R+K +  +   +++ +L  +D+ D+K C C+
Sbjct: 440 STDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCD 499

Query: 496 FVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQ 555
              EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ
Sbjct: 500 VSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQ 559

Query: 556 SRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYM 614
           +RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++IY 
Sbjct: 560 TRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQ 619

Query: 615 Q--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSSTGQ 667
           Q  R G       A F     E E    Y SP DS++        GC+ +   ++ S G 
Sbjct: 620 QVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGL 679

Query: 668 KNFSAP 673
           +    P
Sbjct: 680 QFILTP 685


>gi|26638655 potassium voltage-gated channel KQT-like protein 4
           isoform b [Homo sapiens]
          Length = 641

 Score =  662 bits (1709), Expect = 0.0
 Identities = 353/638 (55%), Positives = 444/638 (69%), Gaps = 54/638 (8%)

Query: 44  GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91
           G  +P+R  +L  P   GA       G+G     +    +  YR+LQN++YNVLERPRGW
Sbjct: 38  GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97

Query: 92  AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151
           AF+YH ++FLLVFSCLVLSV STI+E+++ +   L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 98  AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157

Query: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211
           CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217

Query: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271
           DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK  N  F +YAD+LWWG
Sbjct: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277

Query: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331
            ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337

Query: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391
           RR PAA LIQ+AWR Y+T++SR  L +TW YY+    +P +SS+       R+       
Sbjct: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDS--ILPSFSSRMGIKDRIRM------- 388

Query: 392 ELLRNLKSKSGLAFRKDPPPEPSPSPRGVAAKGKGSPQAQTVRRSPSADQSLE-DSPSKV 450
                     G + R+  P +   +P              T+  SPS++Q  E  SP+KV
Sbjct: 389 ----------GSSQRRTGPSKQHLAP-------------PTMPTSPSSEQVGEATSPTKV 425

Query: 451 PKSWSFGDRSRARQAFRIKGAASRQNSEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIR 510
            KSWSF DR+R R + R+K   S +++    P E++ ++KS  CE   +D+ P +K  IR
Sbjct: 426 QKSWSFNDRTRFRASLRLKPRTSAEDA----PSEEVAEEKSYQCELTVDDIMPAVKTVIR 481

Query: 511 AVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPA--I 568
           ++ +++FLV+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP    
Sbjct: 482 SIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRK 541

Query: 569 TDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEA 626
             +   KGP++AE+ ++ SMMGR+ KVEKQV S+E KLD L+  Y +  R G   +    
Sbjct: 542 AREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAV 601

Query: 627 YFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSS 664
                +P+    YHSP D  E +      + I RS S+
Sbjct: 602 QVPLFDPDITSDYHSPVD-HEDISVSAQTLSISRSVST 638


>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
           sapiens]
          Length = 872

 Score =  662 bits (1709), Expect = 0.0
 Identities = 409/893 (45%), Positives = 525/893 (58%), Gaps = 116/893 (12%)

Query: 4   KSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGS-------EAPKRGSILSK 56
           + R  G+ PG   +  L +G  G D       +DG LL+ G          P+   +L+K
Sbjct: 39  EERKVGLAPGDVEQVTLALG-AGAD-------KDGTLLLEGGGRDEGQRRTPQGIGLLAK 90

Query: 57  PRAGGAGAGKPPKRN-AFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTI 115
                    +P KRN A YR++Q  +Y+ LERPRGWA +YHA VFL+V  CL+L+V +T 
Sbjct: 91  -----TPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTF 145

Query: 116 KEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMV 175
           KEYE  S   L +LE   I +FG E+ +RIWAAGCCCRY+GWRGRLKFARKP C++DI V
Sbjct: 146 KEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFV 205

Query: 176 LIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
           LIAS+ V+A G+QGNV ATS LRSLRFLQILRM+RMDRRGGTWKLLGS + AHSKEL+TA
Sbjct: 206 LIASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITA 264

Query: 236 WYIGFLCLILASFLVYLAEK--------GEN--DHFDTYADALWWGLITLTTIGYGDKYP 285
           WYIGFL LIL+SFLVYL EK        GE   + F+TYADALWWGLITL TIGYGDK P
Sbjct: 265 WYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTP 324

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
           +TW GRL+AATF+LIGVSFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQ+AWR
Sbjct: 325 KTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWR 384

Query: 346 FYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAF 405
           +YATN +R DL +TW++YE  V+ P +  +     +S+ +  L+++ L            
Sbjct: 385 YYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLLDRVRL------------ 432

Query: 406 RKDPPPEPSPSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQA 465
                     +PRG   KGK          +P    ++E+SPSK PK     ++ R R A
Sbjct: 433 ---------SNPRGSNTKGK--------LFTPLNVDAIEESPSKEPKPVGLNNKERFRTA 475

Query: 466 FRIKGAASRQNSEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFK 525
           FR+K  A  Q+SE +  G+ + +D+    +F  ED+ P LK +IRAV +++F + K+KFK
Sbjct: 476 FRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFK 535

Query: 526 ESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDR--TKG------- 576
           E+LRPYDV DVIEQYSAGHLDMLSRIK LQ+R+D I   GP  T K +   KG       
Sbjct: 536 ETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPS 595

Query: 577 ------------PAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTET 624
                       P+ +E+ ED SMMG+  KVE+QV  M KKLDFLV+++MQ M     + 
Sbjct: 596 QQSPRNEPYVARPSTSEI-EDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQV 654

Query: 625 EAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPS 684
             Y+  K           ED     +R+  +  I+ + S TG       P  PP      
Sbjct: 655 TEYYPTKGTSSPAEAEKKED-----NRYSDLKTIICNYSETG-------PPEPPYSFHQV 702

Query: 685 T----------SWQPQSHPRQG------HGTSPVGDHGSLVRIPPPPAHERSLSAYGGGN 728
           T          +  P + PR G        T P      + R    P      S     +
Sbjct: 703 TIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHS 762

Query: 729 RASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNS 788
           +A ++     D    R      RDSDT +S+ SV+HEELERS SGFSISQ +++     +
Sbjct: 763 QADLQG-PYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPN 821

Query: 789 CYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK 841
                +   + + Y+AEGE+DTD+D  TP G  P S+TG+G   D  W    K
Sbjct: 822 ---GGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDG-ISDSVWTPSNK 870


>gi|26638653 potassium voltage-gated channel KQT-like protein 4
           isoform a [Homo sapiens]
          Length = 695

 Score =  659 bits (1701), Expect = 0.0
 Identities = 359/678 (52%), Positives = 456/678 (67%), Gaps = 80/678 (11%)

Query: 44  GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91
           G  +P+R  +L  P   GA       G+G     +    +  YR+LQN++YNVLERPRGW
Sbjct: 38  GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97

Query: 92  AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151
           AF+YH ++FLLVFSCLVLSV STI+E+++ +   L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 98  AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157

Query: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211
           CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217

Query: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271
           DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK  N  F +YAD+LWWG
Sbjct: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277

Query: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331
            ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337

Query: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391
           RR PAA LIQ+AWR Y+T++SR  L +TW YY+                   ++P   +L
Sbjct: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD------------------SILPSFREL 379

Query: 392 ELL--RNLKSKSG----LAFRKDPPPEPSPSP---------------------------- 417
            LL     ++++G    L  R+ P P+ +PS                             
Sbjct: 380 ALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDR 439

Query: 418 -RGVAAKGKGSPQAQ-----TVRRSPSADQSLE-DSPSKVPKSWSFGDRSRARQAFRIKG 470
            R  +++ +  P  Q     T+  SPS++Q  E  SP+KV KSWSF DR+R R + R+K 
Sbjct: 440 IRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKP 499

Query: 471 AASRQNSEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRP 530
             S +++    P E++ ++KS  CE   +D+ P +K  IR++ +++FLV+KRKFKE+LRP
Sbjct: 500 RTSAEDA----PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRP 555

Query: 531 YDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDPSM 588
           YDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP      +   KGP++AE+ ++ SM
Sbjct: 556 YDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISM 615

Query: 589 MGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPEDSR 646
           MGR+ KVEKQV S+E KLD L+  Y +  R G   +         +P+    YHSP D  
Sbjct: 616 MGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD-H 674

Query: 647 EHVDRHGCIVKIVRSSSS 664
           E +      + I RS S+
Sbjct: 675 EDISVSAQTLSISRSVST 692


>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 5 [Homo sapiens]
          Length = 822

 Score =  474 bits (1219), Expect = e-133
 Identities = 241/368 (65%), Positives = 282/368 (76%), Gaps = 17/368 (4%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +     + + Q
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTKKEQ 410

Query: 378 TYGASRLI 385
              +SR++
Sbjct: 411 GEASSRIM 418



 Score =  138 bits (347), Expect = 2e-32
 Identities = 85/168 (50%), Positives = 106/168 (63%), Gaps = 8/168 (4%)

Query: 514 VMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITD-KD 572
           +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQI+G+G   +D K 
Sbjct: 417 IMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKS 476

Query: 573 RTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGA 630
           R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++IY Q  R G       A F  
Sbjct: 477 REKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQI 536

Query: 631 K--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSSTGQKNFSAP 673
              E E    Y SP DS++        GC+ +   ++ S G +    P
Sbjct: 537 PPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTP 584


>gi|32479527 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 1 [Homo sapiens]
          Length = 676

 Score =  395 bits (1016), Expect = e-110
 Identities = 234/600 (39%), Positives = 343/600 (57%), Gaps = 50/600 (8%)

Query: 29  PGAPDSTRDGALLIAGSEAPKRGSILSKPRAGGAGAGKPPKRNAFYRKLQNFLYNVLERP 88
           P  P S    A     S+   R  +   PR       +P         +Q  +YN LERP
Sbjct: 61  PAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTH---VQGRVYNFLERP 117

Query: 89  RGW-AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWA 147
            GW  F+YH  VFL+V  CL+ SV STI++Y   + G L+ +EIV +V FG EY VR+W+
Sbjct: 118 TGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWS 177

Query: 148 AGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILR 207
           AGC  +Y G  GRL+FARKP  +ID++V++AS+ VL  GS+G VFATSA+R +RFLQILR
Sbjct: 178 AGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILR 237

Query: 208 MIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND-----HFD 262
           M+ +DR+GGTW+LLGSVV+ H +EL+T  YIGFL LI +S+ VYLAEK   +      F 
Sbjct: 238 MLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFG 297

Query: 263 TYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQE 322
           +YADALWWG++T+TTIGYGDK PQTW G+ +A+ F++  +SFFALPAGILGSGFALKVQ+
Sbjct: 298 SYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQ 357

Query: 323 QHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGAS 382
           + RQKHF ++   AA LIQ+AWR YA   +     STW+ Y R                 
Sbjct: 358 KQRQKHFNRQIPAAASLIQTAWRCYA---AENPDSSTWKIYIRKAPRSHTLLSPSPKPKK 414

Query: 383 RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSPRGVAAKGKGSPQAQTVRRSPSADQS 442
            ++    + +L ++     G      P     P                +VR+SP+    
Sbjct: 415 SVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL--- 471

Query: 443 LEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEASLPGEDIVDDKSCPCEFVTEDLT 502
           LE S     ++ SF +                   +  L GE ++     P   +++ L 
Sbjct: 472 LEVSMPHFMRTNSFAE-------------------DLDLEGETLL----TPITHISQ-LR 507

Query: 503 PGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIV 562
              + +I+ +  M++ V+K+KF+++ +PYDV DVIEQYS GHL+++ RIK LQ R+DQ +
Sbjct: 508 EHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSI 567

Query: 563 GRGP---AITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGI 619
           G+     ++++K + +G          ++  RL +VE +V  ++++L  + ++  Q + +
Sbjct: 568 GKPSLFISVSEKSKDRG--------SNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSL 619


>gi|32479525 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 2 [Homo sapiens]
          Length = 549

 Score =  370 bits (950), Expect = e-102
 Identities = 212/528 (40%), Positives = 315/528 (59%), Gaps = 46/528 (8%)

Query: 100 FLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
           FL+V  CL+ SV STI++Y   + G L+ +EIV +V FG EY VR+W+AGC  +Y G  G
Sbjct: 3   FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62

Query: 160 RLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWK 219
           RL+FARKP  +ID++V++AS+ VL  GS+G VFATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 63  RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122

Query: 220 LLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND-----HFDTYADALWWGLIT 274
           LLGSVV+ H +EL+T  YIGFL LI +S+ VYLAEK   +      F +YADALWWG++T
Sbjct: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182

Query: 275 LTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRN 334
           +TTIGYGDK PQTW G+ +A+ F++  +SFFALPAGILGSGFALKVQ++ RQKHF ++  
Sbjct: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242

Query: 335 PAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELL 394
            AA LIQ+AWR YA   +     STW+ Y R                  ++    + +L 
Sbjct: 243 AAASLIQTAWRCYA---AENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLD 299

Query: 395 RNLKSKSGLAFRKDPPPEPSPSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSW 454
           ++     G      P     P                +VR+SP+    LE S     ++ 
Sbjct: 300 KDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL---LEVSMPHFMRTN 356

Query: 455 SFGDRSRARQAFRIKGAASRQNSEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCV 514
           SF +                   +  L GE ++     P   +++ L    + +I+ +  
Sbjct: 357 SFAE-------------------DLDLEGETLL----TPITHISQ-LREHHRATIKVIRR 392

Query: 515 MRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGP---AITDK 571
           M++ V+K+KF+++ +PYDV DVIEQYS GHL+++ RIK LQ R+DQ +G+     ++++K
Sbjct: 393 MQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEK 452

Query: 572 DRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGI 619
            + +G          ++  RL +VE +V  ++++L  + ++  Q + +
Sbjct: 453 SKDRG--------SNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSL 492


>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2a [Homo sapiens]
          Length = 613

 Score =  104 bits (260), Expect = 3e-22
 Identities = 77/292 (26%), Positives = 137/292 (46%), Gaps = 44/292 (15%)

Query: 62  AGAGKPPKRNAFYRKLQNFLYNVLERP---RGWAFIYHAYVFLLVFS----CL------- 107
           AG G P  ++  +R+LQ  ++ + E P   R   FI  A +F ++ S    CL       
Sbjct: 196 AGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFN 255

Query: 108 --------VLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
                   V++  S + +YE  ++ AL  +E V +V F  E+ VRI  +           
Sbjct: 256 IVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSP---------N 306

Query: 160 RLKFARKPFCVIDIMVLIA---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGG 216
           +L+F +    +ID + ++     + +    S+        LR +RF++ILR+ ++ R   
Sbjct: 307 KLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFV 366

Query: 217 TWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEK----------GENDHFDTYAD 266
             ++LG  + A + E +       L +++ + ++Y AE+           E+  F     
Sbjct: 367 GLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPI 426

Query: 267 ALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFAL 318
             WW ++T+TT+GYGD YPQTW+G L+ A   L GV   A+P  ++ + F +
Sbjct: 427 GFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2b [Homo sapiens]
          Length = 638

 Score =  104 bits (260), Expect = 3e-22
 Identities = 77/292 (26%), Positives = 137/292 (46%), Gaps = 44/292 (15%)

Query: 62  AGAGKPPKRNAFYRKLQNFLYNVLERP---RGWAFIYHAYVFLLVFS----CL------- 107
           AG G P  ++  +R+LQ  ++ + E P   R   FI  A +F ++ S    CL       
Sbjct: 196 AGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFN 255

Query: 108 --------VLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
                   V++  S + +YE  ++ AL  +E V +V F  E+ VRI  +           
Sbjct: 256 IVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSP---------N 306

Query: 160 RLKFARKPFCVIDIMVLIA---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGG 216
           +L+F +    +ID + ++     + +    S+        LR +RF++ILR+ ++ R   
Sbjct: 307 KLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFV 366

Query: 217 TWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEK----------GENDHFDTYAD 266
             ++LG  + A + E +       L +++ + ++Y AE+           E+  F     
Sbjct: 367 GLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPI 426

Query: 267 ALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFAL 318
             WW ++T+TT+GYGD YPQTW+G L+ A   L GV   A+P  ++ + F +
Sbjct: 427 GFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2c [Homo sapiens]
          Length = 558

 Score =  104 bits (260), Expect = 3e-22
 Identities = 77/292 (26%), Positives = 137/292 (46%), Gaps = 44/292 (15%)

Query: 62  AGAGKPPKRNAFYRKLQNFLYNVLERP---RGWAFIYHAYVFLLVFS----CL------- 107
           AG G P  ++  +R+LQ  ++ + E P   R   FI  A +F ++ S    CL       
Sbjct: 196 AGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFN 255

Query: 108 --------VLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
                   V++  S + +YE  ++ AL  +E V +V F  E+ VRI  +           
Sbjct: 256 IVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSP---------N 306

Query: 160 RLKFARKPFCVIDIMVLIA---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGG 216
           +L+F +    +ID + ++     + +    S+        LR +RF++ILR+ ++ R   
Sbjct: 307 KLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFV 366

Query: 217 TWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEK----------GENDHFDTYAD 266
             ++LG  + A + E +       L +++ + ++Y AE+           E+  F     
Sbjct: 367 GLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPI 426

Query: 267 ALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFAL 318
             WW ++T+TT+GYGD YPQTW+G L+ A   L GV   A+P  ++ + F +
Sbjct: 427 GFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|119395748 potassium voltage-gated channel subfamily A member 1
           [Homo sapiens]
          Length = 495

 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 61/199 (30%), Positives = 99/199 (49%), Gaps = 18/199 (9%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAA- 185
           +I+E + I+ F  E  VR +A            +  F +     IDI+ +I     L   
Sbjct: 222 FIVETLCIIWFSFELVVRFFACP---------SKTDFFKNIMNFIDIVAIIPYFITLGTE 272

Query: 186 -----GSQGNVFATSA--LRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYI 238
                G+Q    ATS   LR +R +++ R+ ++ R     ++LG  + A  +EL    + 
Sbjct: 273 IAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFF 332

Query: 239 GFLCLILASFLVYLAEKGEND-HFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATF 297
            F+ +IL S  VY AE  E + HF +  DA WW ++++TT+GYGD YP T  G+++ +  
Sbjct: 333 LFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLC 392

Query: 298 TLIGVSFFALPAGILGSGF 316
            + GV   ALP  ++ S F
Sbjct: 393 AIAGVLTIALPVPVIVSNF 411


>gi|88758565 potassium voltage-gated channel, shaker-related
           subfamily, member 3 [Homo sapiens]
          Length = 575

 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 58/197 (29%), Positives = 99/197 (50%), Gaps = 16/197 (8%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLA-- 184
           +++E + I+ F  E  VR +A            +  F+R    +IDI+ +I     L   
Sbjct: 296 FVVETLCIIWFSFELLVRFFACP---------SKATFSRNIMNLIDIVAIIPYFITLGTE 346

Query: 185 -AGSQGN---VFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
            A  QGN     + + LR +R +++ R+ ++ R     ++LG  + A  +EL    +  F
Sbjct: 347 LAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF 406

Query: 241 LCLILASFLVYLAEKGE-NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTL 299
           + +IL S  VY AE  +    F +  DA WW ++T+TT+GYGD +P T  G+++ +   +
Sbjct: 407 IGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAI 466

Query: 300 IGVSFFALPAGILGSGF 316
            GV   ALP  ++ S F
Sbjct: 467 AGVLTIALPVPVIVSNF 483


>gi|4504817 potassium voltage-gated channel, shaker-related
           subfamily, member 4 [Homo sapiens]
          Length = 653

 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 59/201 (29%), Positives = 97/201 (48%), Gaps = 20/201 (9%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAA- 185
           +I+E V IV F  E+ VR +A            +  F +    +IDI+ ++     L   
Sbjct: 372 FIVETVCIVWFSFEFVVRCFACP---------SQALFFKNIMNIIDIVSILPYFITLGTD 422

Query: 186 ---------GSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAW 236
                    G Q    + + LR +R +++ R+ ++ R     ++LG  + A  +EL    
Sbjct: 423 LAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLI 482

Query: 237 YIGFLCLILASFLVYLAEKGE-NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAA 295
           +  F+ +IL S  VY AE  E   HF +  DA WW ++T+TT+GYGD  P T  G+++ +
Sbjct: 483 FFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGS 542

Query: 296 TFTLIGVSFFALPAGILGSGF 316
              + GV   ALP  ++ S F
Sbjct: 543 LCAIAGVLTIALPVPVIVSNF 563


>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
           member 1 [Homo sapiens]
          Length = 858

 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 73/268 (27%), Positives = 132/268 (49%), Gaps = 24/268 (8%)

Query: 81  LYNVLERPRGWA---FIYHAYVFLLVFSCLVLSV-----FSTIKEYEKSSEGA-LYILEI 131
           L+++LE+P        +    +  +V S + LS+       ++ E+ +S++   L  +E 
Sbjct: 175 LWDLLEKPNSSVAAKILAIISIMFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEA 234

Query: 132 VTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIAS-IAVLAAGSQGN 190
           V I  F +EY +R  ++      + W    KF + P   ID++ ++   + +    S  +
Sbjct: 235 VCIAWFTMEYLLRFLSSP-----KKW----KFFKGPLNAIDLLAILPYYVTIFLTESNKS 285

Query: 191 VFATSALRSL----RFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILA 246
           V     +R +    R ++ILR++++ R     + LG  +     EL        + +++ 
Sbjct: 286 VLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIF 345

Query: 247 SFLVYLAEKGEND-HFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFF 305
           S LV+ AEK E+D  F +   + WW  IT+TT+GYGD YP+T  G+++     + GV   
Sbjct: 346 SSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVI 405

Query: 306 ALPAGILGSGFALKVQEQHRQKHFEKRR 333
           ALP  I+ + F+   +EQ RQ+   KRR
Sbjct: 406 ALPIPIIVNNFSEFYKEQKRQEKAIKRR 433


>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
           isoform A [Homo sapiens]
          Length = 585

 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 70/298 (23%), Positives = 131/298 (43%), Gaps = 43/298 (14%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V +V F  E+ +R+              +++F +    +ID + ++ 
Sbjct: 238 EAETEAFLTYIEGVCVVWFTFEFLMRVIFCP---------NKVEFIKNSLNIIDFVAILP 288

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 289 FYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 348

Query: 236 WYIGFLCLILASFLVYLAEK----------GENDHFDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+           E+ HF       WW ++T+TT+GYGD YP
Sbjct: 349 IIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYP 408

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
           QTW+G L+ A   L GV   A+P  ++ + F +       ++   K++            
Sbjct: 409 QTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKK----------- 457

Query: 346 FYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGL 403
               ++ R     +  Y +  V  P +S+Q+ T        PL Q E+L   ++ S L
Sbjct: 458 ---KHIPRPPQLGSPNYCKSVVNSPHHSTQSDTC-------PLAQEEILEINRADSKL 505


>gi|27436974 potassium voltage-gated channel, Shab-related
           subfamily, member 2 [Homo sapiens]
          Length = 911

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 73/269 (27%), Positives = 131/269 (48%), Gaps = 26/269 (9%)

Query: 81  LYNVLERPRGWA---FIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGA-------LYILE 130
           L+++LE+P        +    +  +V S + LS+ +T+ E +++ E         L  +E
Sbjct: 179 LWDLLEKPNSSVAAKILAIVSILFIVLSTIALSL-NTLPELQETDEFGQLNDNRQLAHVE 237

Query: 131 IVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIAS-IAVLAAGSQG 189
            V I  F +EY +R  ++           + KF + P  VID++ ++   + +    S  
Sbjct: 238 AVCIAWFTMEYLLRFLSSP---------NKWKFFKGPLNVIDLLAILPYYVTIFLTESNK 288

Query: 190 NVFATSALRSL----RFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLIL 245
           +V     +R +    R ++ILR++++ R     + LG  +     EL        + +++
Sbjct: 289 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 348

Query: 246 ASFLVYLAEKGEN-DHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSF 304
            S LV+ AEK E+   F +   + WW  IT+TT+GYGD YP+T  G+++     + GV  
Sbjct: 349 FSSLVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLV 408

Query: 305 FALPAGILGSGFALKVQEQHRQKHFEKRR 333
            ALP  I+ + F+   +EQ RQ+   KRR
Sbjct: 409 IALPIPIIVNNFSEFYKEQKRQEKAIKRR 437


>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
           isoform B [Homo sapiens]
          Length = 511

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 68/289 (23%), Positives = 127/289 (43%), Gaps = 43/289 (14%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V +V F  E+ +R+              +++F +    +ID + ++ 
Sbjct: 238 EAETEAFLTYIEGVCVVWFTFEFLMRVIFCP---------NKVEFIKNSLNIIDFVAILP 288

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 289 FYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 348

Query: 236 WYIGFLCLILASFLVYLAEK----------GENDHFDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+           E+ HF       WW ++T+TT+GYGD YP
Sbjct: 349 IIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYP 408

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
           QTW+G L+ A   L GV   A+P  ++ + F +       ++   K++            
Sbjct: 409 QTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKK----------- 457

Query: 346 FYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELL 394
               ++ R     +  Y +  V  P +S+Q+ T        PL Q E+L
Sbjct: 458 ---KHIPRPPQLGSPNYCKSVVNSPHHSTQSDTC-------PLAQEEIL 496


>gi|27436984 potassium voltage-gated channel, Shal-related
           subfamily, member 3 isoform 1 [Homo sapiens]
          Length = 655

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 68/287 (23%), Positives = 134/287 (46%), Gaps = 16/287 (5%)

Query: 125 ALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLA 184
           A + L+   +++F VEY +R++AA           R +F R    +ID++ ++     L 
Sbjct: 225 AFFCLDTACVMIFTVEYLLRLFAAP---------SRYRFIRSVMSIIDVVAIMPYYIGLV 275

Query: 185 AGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLI 244
             +  +V  + A  +LR  ++ R+ +  R     ++LG  + + + EL    +   + +I
Sbjct: 276 MTNNEDV--SGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAII 333

Query: 245 LASFLVYLAEKGEN-DHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVS 303
           + + +++ AEKG +   F +   + W+ ++T+TT+GYGD  P+T  G++  +  +L GV 
Sbjct: 334 IFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVL 393

Query: 304 FFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYY 363
             ALP  ++ S F+   +  H+ +  +KRR      + +  R   T  S   LHS     
Sbjct: 394 VIALPVPVIVSNFS---RIYHQNQRADKRRAQKKARL-ARIRVAKTGSSNAYLHSKRNGL 449

Query: 364 ERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPP 410
                    + + +  G +  +       LL  L+  +GL++  D P
Sbjct: 450 LNEALELTGTPEEEHMGKTTSLIESQHHHLLHCLEKTTGLSYLVDDP 496


>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
           isoform c [Homo sapiens]
          Length = 626

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 61/228 (26%), Positives = 108/228 (47%), Gaps = 22/228 (9%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V ++ F +E+ VRI     CC        L F +    +ID + ++ 
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILP 324

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 325 FYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384

Query: 236 WYIGFLCLILASFLVYLAEK--------GENDH--FDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+          NDH  F       WW ++T+TT+GYGD YP
Sbjct: 385 IIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYP 444

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRR 333
           +TW+G L+ A   L GV   A+P  ++ + F +       ++   K+R
Sbjct: 445 KTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
           isoform a [Homo sapiens]
          Length = 635

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 61/228 (26%), Positives = 108/228 (47%), Gaps = 22/228 (9%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V ++ F +E+ VRI     CC        L F +    +ID + ++ 
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILP 324

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 325 FYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384

Query: 236 WYIGFLCLILASFLVYLAEK--------GENDH--FDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+          NDH  F       WW ++T+TT+GYGD YP
Sbjct: 385 IIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYP 444

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRR 333
           +TW+G L+ A   L GV   A+P  ++ + F +       ++   K+R
Sbjct: 445 KTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
           isoform b [Homo sapiens]
          Length = 582

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 61/228 (26%), Positives = 108/228 (47%), Gaps = 22/228 (9%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V ++ F +E+ VRI     CC        L F +    +ID + ++ 
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILP 324

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 325 FYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384

Query: 236 WYIGFLCLILASFLVYLAEK--------GENDH--FDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+          NDH  F       WW ++T+TT+GYGD YP
Sbjct: 385 IIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYP 444

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRR 333
           +TW+G L+ A   L GV   A+P  ++ + F +       ++   K+R
Sbjct: 445 KTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|4504821 potassium voltage-gated channel, shaker-related
           subfamily, member 6 [Homo sapiens]
          Length = 529

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 58/207 (28%), Positives = 98/207 (47%), Gaps = 26/207 (12%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVL--- 183
           +++E + IV F  E  VR  A            +  F R    +ID++ +      L   
Sbjct: 264 FLVETLCIVWFTFELLVRFSACP---------SKPAFFRNIMNIIDLVAIFPYFITLGTE 314

Query: 184 ---------AAGSQGN----VFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSK 230
                    A+G  G       + + LR +R +++ R+ ++ R     ++LG  + A  +
Sbjct: 315 LVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMR 374

Query: 231 ELVTAWYIGFLCLILASFLVYLAEKGENDH-FDTYADALWWGLITLTTIGYGDKYPQTWN 289
           EL    +  F+ +IL S  VY AE  ++D  F +  DA WW ++T+TT+GYGD YP T  
Sbjct: 375 ELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVG 434

Query: 290 GRLLAATFTLIGVSFFALPAGILGSGF 316
           G+++ +   + GV   ALP  ++ S F
Sbjct: 435 GKIVGSLCAIAGVLTIALPVPVIVSNF 461


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,586,600
Number of Sequences: 37866
Number of extensions: 1985174
Number of successful extensions: 11077
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 101
Number of HSP's successfully gapped in prelim test: 166
Number of HSP's that attempted gapping in prelim test: 10321
Number of HSP's gapped (non-prelim): 824
length of query: 841
length of database: 18,247,518
effective HSP length: 111
effective length of query: 730
effective length of database: 14,044,392
effective search space: 10252406160
effective search space used: 10252406160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.