Search of human proteins with 25777682

Search of human proteins with 25777682

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25777682 Ras association domain family 1 isoform C [Homo
sapiens]
         (270 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25777682 Ras association domain family 1 isoform C [Homo sapi...   541   e-154
gi|25777684 Ras association domain family 1 isoform D [Homo sapi...   442   e-124
gi|20149588 Ras association domain family 1 isoform A [Homo sapi...   442   e-124
gi|25777680 Ras association domain family 1 isoform B [Homo sapi...   378   e-105
gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isofor...   243   1e-64
gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isofor...   225   4e-59
gi|30039698 Ras association (RalGDS/AF-6) domain family member 3...   184   9e-47
gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isofor...   132   4e-31
gi|23510360 Ras association domain family 4 [Homo sapiens]             62   5e-10
gi|25777677 Ras association domain family 2 [Homo sapiens]             62   7e-10
gi|7661964 Ras association domain family 2 [Homo sapiens]              62   7e-10
gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isofor...    59   4e-09
gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isofor...    59   4e-09
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora...    35   0.069
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora...    33   0.20 
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora...    33   0.20 
gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens]                     31   1.3  
gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens]                     31   1.3  
gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens]                     31   1.3  
gi|191252814 RIMS binding protein 3B [Homo sapiens]                    30   2.2  
gi|191252806 RIMS binding protein 3C [Homo sapiens]                    30   2.2  
gi|153792195 DKFZP434H0735 protein [Homo sapiens]                      30   2.2  
gi|33342268 hypothetical protein LOC91300 [Homo sapiens]               30   2.2  
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]        30   2.9  
gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens]           30   2.9  
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]         30   2.9  
gi|4826870 nucleobindin 2 [Homo sapiens]                               29   4.9  
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...    29   4.9  
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]            29   4.9  
gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]              29   4.9  

>gi|25777682 Ras association domain family 1 isoform C [Homo
           sapiens]
          Length = 270

 Score =  541 bits (1393), Expect = e-154
 Identities = 270/270 (100%), Positives = 270/270 (100%)

Query: 1   MGEAEAPSFEMTWSSTTSSGYCSQEDSDSELEQYFTARTSLARRPRRDQDEPVEWETPDL 60
           MGEAEAPSFEMTWSSTTSSGYCSQEDSDSELEQYFTARTSLARRPRRDQDEPVEWETPDL
Sbjct: 1   MGEAEAPSFEMTWSSTTSSGYCSQEDSDSELEQYFTARTSLARRPRRDQDEPVEWETPDL 60

Query: 61  SQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARR 120
           SQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARR
Sbjct: 61  SQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARR 120

Query: 121 GPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAER 180
           GPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAER
Sbjct: 121 GPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAER 180

Query: 181 HGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQR 240
           HGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQR
Sbjct: 181 HGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQR 240

Query: 241 EEEEHLRQILQKYSYCRQKIQEALHACPLG 270
           EEEEHLRQILQKYSYCRQKIQEALHACPLG
Sbjct: 241 EEEEHLRQILQKYSYCRQKIQEALHACPLG 270


>gi|25777684 Ras association domain family 1 isoform D [Homo
           sapiens]
          Length = 344

 Score =  442 bits (1138), Expect = e-124
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 50  DEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSS 109
           DEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSS
Sbjct: 124 DEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSS 183

Query: 110 KKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDP 169
           KKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDP
Sbjct: 184 KKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDP 243

Query: 170 RKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMP 229
           RKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMP
Sbjct: 244 RKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMP 303

Query: 230 ELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG 270
           ELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
Sbjct: 304 ELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG 344


>gi|20149588 Ras association domain family 1 isoform A [Homo
           sapiens]
          Length = 340

 Score =  442 bits (1138), Expect = e-124
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 50  DEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSS 109
           DEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSS
Sbjct: 120 DEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSS 179

Query: 110 KKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDP 169
           KKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDP
Sbjct: 180 KKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDP 239

Query: 170 RKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMP 229
           RKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMP
Sbjct: 240 RKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMP 299

Query: 230 ELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG 270
           ELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
Sbjct: 300 ELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG 340


>gi|25777680 Ras association domain family 1 isoform B [Homo
           sapiens]
          Length = 189

 Score =  378 bits (970), Expect = e-105
 Identities = 189/189 (100%), Positives = 189/189 (100%)

Query: 82  MSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAV 141
           MSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAV
Sbjct: 1   MSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAV 60

Query: 142 KHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLL 201
           KHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLL
Sbjct: 61  KHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLL 120

Query: 202 AGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQ 261
           AGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQ
Sbjct: 121 AGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQ 180

Query: 262 EALHACPLG 270
           EALHACPLG
Sbjct: 181 EALHACPLG 189


>gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isoform C
           [Homo sapiens]
          Length = 265

 Score =  243 bits (621), Expect = 1e-64
 Identities = 132/260 (50%), Positives = 180/260 (69%), Gaps = 9/260 (3%)

Query: 11  MTWSSTTSSGYCSQEDSDSELEQ-YFTARTSLARRPR-----RDQDEPVEWETPDLSQAE 64
           MT  S+ SSGYCS    D ELE  +FTA+T+  R  +     ++  +PVE      +  E
Sbjct: 1   MTVDSSMSSGYCSL---DEELEDCFFTAKTTFFRNAQSKHLSKNVCKPVEETQRPPTLQE 57

Query: 65  IEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGR 124
           I+QKI  YN +  + L M L++DG+YTGFIKV LKL RPV+VP+  +P S+ DA +    
Sbjct: 58  IKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNL 117

Query: 125 GTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQV 184
             +  +RTSFYLP DA+K LH+ S T   EVI+ LL+KF+VVD+P+KFALF+R  + GQV
Sbjct: 118 AATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQV 177

Query: 185 YLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEE 244
             +KL   ++PL LRLLAGP  + LSFVLKEN++GEV WDAFS+PEL NFL IL++EE++
Sbjct: 178 LFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQD 237

Query: 245 HLRQILQKYSYCRQKIQEAL 264
            ++Q+ +KY   RQK++EAL
Sbjct: 238 KIQQVQKKYDKFRQKLEEAL 257


>gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isoform A
           [Homo sapiens]
          Length = 418

 Score =  225 bits (573), Expect = 4e-59
 Identities = 114/214 (53%), Positives = 155/214 (72%)

Query: 51  EPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSK 110
           +PVE      +  EI+QKI  YN +  + L M L++DG+YTGFIKV LKL RPV+VP+  
Sbjct: 197 KPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGI 256

Query: 111 KPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPR 170
           +P S+ DA +      +  +RTSFYLP DA+K LH+ S T   EVI+ LL+KF+VVD+P+
Sbjct: 257 RPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQ 316

Query: 171 KFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPE 230
           KFALF+R  + GQV  +KL   ++PL LRLLAGP  + LSFVLKEN++GEV WDAFS+PE
Sbjct: 317 KFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPE 376

Query: 231 LHNFLRILQREEEEHLRQILQKYSYCRQKIQEAL 264
           L NFL IL++EE++ ++Q+ +KY   RQK++EAL
Sbjct: 377 LQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEAL 410


>gi|30039698 Ras association (RalGDS/AF-6) domain family member 3
           [Homo sapiens]
          Length = 238

 Score =  184 bits (466), Expect = 9e-47
 Identities = 116/256 (45%), Positives = 151/256 (58%), Gaps = 35/256 (13%)

Query: 18  SSGYCSQEDSDSELEQYFTARTSLARR-----PRR-DQDEPVEWETPD-LSQAEIEQKIK 70
           SSGY S E+   +   +FTARTS  RR     PR   QD   E ET   LS+ EI++K+ 
Sbjct: 2   SSGYSSLEEDAEDF--FFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVH 59

Query: 71  EYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRP--VSVPSSKKPPSLQDARRGPGRGTSV 128
           +YN  +   L M+LN +G YTGFIKVQ++L +P   S  S K  PS              
Sbjct: 60  KYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPS-------------- 105

Query: 129 RRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRK 188
                       +  LH+ S     EVIEALL+KFLV + P KFAL++R  R  QVY  K
Sbjct: 106 --------SNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACK 157

Query: 189 LLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQ 248
           L D E PL LRL+AGP    LSFVL+E++ GE  W+AFS+PEL NFLRIL +EE+E L+ 
Sbjct: 158 LSDREHPLYLRLVAGPRTDTLSFVLREHEIGE--WEAFSLPELQNFLRILDKEEDEQLQN 215

Query: 249 ILQKYSYCRQKIQEAL 264
           + ++Y+  RQK++EAL
Sbjct: 216 LKRRYTAYRQKLEEAL 231


>gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isoform B
           [Homo sapiens]
          Length = 336

 Score =  132 bits (331), Expect = 4e-31
 Identities = 68/134 (50%), Positives = 92/134 (68%)

Query: 51  EPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSK 110
           +PVE      +  EI+QKI  YN +  + L M L++DG+YTGFIKV LKL RPV+VP+  
Sbjct: 197 KPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGI 256

Query: 111 KPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPR 170
           +P S+ DA +      +  +RTSFYLP DA+K LH+ S T   EVI+ LL+KF+VVD+P+
Sbjct: 257 RPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQ 316

Query: 171 KFALFERAERHGQV 184
           KFALF+R  + GQV
Sbjct: 317 KFALFKRIHKDGQV 330


>gi|23510360 Ras association domain family 4 [Homo sapiens]
          Length = 321

 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 53/173 (30%), Positives = 78/173 (45%), Gaps = 32/173 (18%)

Query: 120 RGPGRGTSVRR------------RTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVV 166
           R PG    +RR            +TS + P   +V ++ V S     +V+  LL KF V 
Sbjct: 154 RAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVE 213

Query: 167 DDPRKFALF---ERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSG---- 219
           D P +FAL+   E  ER       KL D E PL  R+L GP +K     L E D G    
Sbjct: 214 DGPSEFALYIVHESGER------TKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVP 267

Query: 220 --EVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCR----QKIQEALHA 266
                +  F MP L +F+  L+ EEE  + ++  K+   R    Q++++ + A
Sbjct: 268 HEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEA 320


>gi|25777677 Ras association domain family 2 [Homo sapiens]
          Length = 326

 Score = 61.6 bits (148), Expect = 7e-10
 Identities = 43/147 (29%), Positives = 75/147 (51%), Gaps = 10/147 (6%)

Query: 125 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQ 183
           G     +TS + P   +V ++ + S     +V++ LL KF + +   +FAL+     H  
Sbjct: 173 GHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVV---HTS 229

Query: 184 VYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDS-GEVNWDA-----FSMPELHNFLRI 237
              +KL   + PL  R+L GP ++     L E D   EV +D      F MP L +F++ 
Sbjct: 230 GEKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQK 289

Query: 238 LQREEEEHLRQILQKYSYCRQKIQEAL 264
           LQ EE+  ++++++KY+  R  I++ L
Sbjct: 290 LQEEEDREVKKLMRKYTVLRLMIRQRL 316


>gi|7661964 Ras association domain family 2 [Homo sapiens]
          Length = 326

 Score = 61.6 bits (148), Expect = 7e-10
 Identities = 43/147 (29%), Positives = 75/147 (51%), Gaps = 10/147 (6%)

Query: 125 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQ 183
           G     +TS + P   +V ++ + S     +V++ LL KF + +   +FAL+     H  
Sbjct: 173 GHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVV---HTS 229

Query: 184 VYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDS-GEVNWDA-----FSMPELHNFLRI 237
              +KL   + PL  R+L GP ++     L E D   EV +D      F MP L +F++ 
Sbjct: 230 GEKQKLKATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQK 289

Query: 238 LQREEEEHLRQILQKYSYCRQKIQEAL 264
           LQ EE+  ++++++KY+  R  I++ L
Sbjct: 290 LQEEEDREVKKLMRKYTVLRLMIRQRL 316


>gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isoform b
           [Homo sapiens]
          Length = 369

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 15/139 (10%)

Query: 125 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFAL---FERAER 180
           G      TS ++P  ++   + V S  R  EVI+ LL+KF + + P+ FAL   F   E+
Sbjct: 215 GHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ 274

Query: 181 HGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDA-----FSMPELHNFL 235
                 R+L   + PL  RLL GPS+K     L + D+ E++ D      F    L + L
Sbjct: 275 ------RRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESIL 328

Query: 236 RILQREEEEHLRQILQKYS 254
           + L  EE+  +++I+ K++
Sbjct: 329 QRLNEEEKREIQRIVTKFN 347


>gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isoform a
           [Homo sapiens]
          Length = 337

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 15/139 (10%)

Query: 125 GTSVRRRTSFYLPK-DAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFAL---FERAER 180
           G      TS ++P  ++   + V S  R  EVI+ LL+KF + + P+ FAL   F   E+
Sbjct: 183 GHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ 242

Query: 181 HGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDA-----FSMPELHNFL 235
                 R+L   + PL  RLL GPS+K     L + D+ E++ D      F    L + L
Sbjct: 243 ------RRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESIL 296

Query: 236 RILQREEEEHLRQILQKYS 254
           + L  EE+  +++I+ K++
Sbjct: 297 QRLNEEEKREIQRIVTKFN 315


>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 4 isoform 2 [Homo
           sapiens]
          Length = 1651

 Score = 35.0 bits (79), Expect = 0.069
 Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 17/121 (14%)

Query: 140 AVKHLHVLSRTRAREVIEALLRKFL----VVDDPRKFALFERAERHGQVYLRKLLDDEQP 195
           A K + V S    ++VIE L  KF     ++  P K++L+E     G+   R+L  DE+P
Sbjct: 56  ATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSP-KYSLYE-VHVSGE---RRLDIDEKP 110

Query: 196 LRLRLLAGPSDKALSFVLK-ENDSGEVNWDAFSMPE-------LHNFLRILQREEEEHLR 247
           L ++L     D+   FVLK END+        + PE       + NF R L ++E++  +
Sbjct: 111 LVVQLNWNKDDREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKK 170

Query: 248 Q 248
           +
Sbjct: 171 K 171


>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 4 isoform 1 [Homo
           sapiens]
          Length = 1834

 Score = 33.5 bits (75), Expect = 0.20
 Identities = 37/120 (30%), Positives = 60/120 (50%), Gaps = 16/120 (13%)

Query: 140 AVKHLHVLSRTRAREVIEALLRKFL----VVDDPRKFALFERAERHGQVYLRKLLDDEQP 195
           A K + V S    ++VIE L  KF     ++  P K++L+E     G+   R+L  DE+P
Sbjct: 56  ATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSP-KYSLYE-VHVSGE---RRLDIDEKP 110

Query: 196 LRLRLLAGPSDKALSFVLK-ENDS----GEVNWDAFSMPE--LHNFLRILQREEEEHLRQ 248
           L ++L     D+   FVLK END+     + N       E  + NF R L ++E++  ++
Sbjct: 111 LVVQLNWNKDDREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKK 170


>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 4 isoform 3 [Homo
           sapiens]
          Length = 1612

 Score = 33.5 bits (75), Expect = 0.20
 Identities = 37/120 (30%), Positives = 60/120 (50%), Gaps = 16/120 (13%)

Query: 140 AVKHLHVLSRTRAREVIEALLRKFL----VVDDPRKFALFERAERHGQVYLRKLLDDEQP 195
           A K + V S    ++VIE L  KF     ++  P K++L+E     G+   R+L  DE+P
Sbjct: 56  ATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSP-KYSLYE-VHVSGE---RRLDIDEKP 110

Query: 196 LRLRLLAGPSDKALSFVLK-ENDS----GEVNWDAFSMPE--LHNFLRILQREEEEHLRQ 248
           L ++L     D+   FVLK END+     + N       E  + NF R L ++E++  ++
Sbjct: 111 LVVQLNWNKDDREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKK 170


>gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens]
          Length = 1137

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 150 TRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKAL 209
           ++A E  + +  K+ V D  + F  F     HG VYL K L+   PLR +L      K L
Sbjct: 231 SKALESRDEVKTKWGVSDFIKAFIKF-----HGHVYLSKSLEKLSPLREKL--EEQFKRL 283

Query: 210 SFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEH 245
            F    N    V+    ++ +LH+ LR    E E+H
Sbjct: 284 LFQKAFNSQQLVHVTVINLFQLHH-LRDFSNETEQH 318


>gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens]
          Length = 1049

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 150 TRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKAL 209
           ++A E  + +  K+ V D  + F  F     HG VYL K L+   PLR +L      K L
Sbjct: 189 SKALESRDEVKTKWGVSDFIKAFIKF-----HGHVYLSKSLEKLSPLREKL--EEQFKRL 241

Query: 210 SFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEH 245
            F    N    V+    ++ +LH+ LR    E E+H
Sbjct: 242 LFQKAFNSQQLVHVTVINLFQLHH-LRDFSNETEQH 276


>gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens]
          Length = 1091

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 150 TRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKAL 209
           ++A E  + +  K+ V D  + F  F     HG VYL K L+   PLR +L      K L
Sbjct: 231 SKALESRDEVKTKWGVSDFIKAFIKF-----HGHVYLSKSLEKLSPLREKL--EEQFKRL 283

Query: 210 SFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEH 245
            F    N    V+    ++ +LH+ LR    E E+H
Sbjct: 284 LFQKAFNSQQLVHVTVINLFQLHH-LRDFSNETEQH 318


>gi|191252814 RIMS binding protein 3B [Homo sapiens]
          Length = 1639

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 14/43 (32%), Positives = 24/43 (55%)

Query: 223 WDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALH 265
           W+A    EL      +QRE E  +RQ+L+     ++++Q+ LH
Sbjct: 80  WEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLH 122


>gi|191252806 RIMS binding protein 3C [Homo sapiens]
          Length = 1639

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 14/43 (32%), Positives = 24/43 (55%)

Query: 223 WDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALH 265
           W+A    EL      +QRE E  +RQ+L+     ++++Q+ LH
Sbjct: 80  WEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLH 122


>gi|153792195 DKFZP434H0735 protein [Homo sapiens]
          Length = 1639

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 14/43 (32%), Positives = 24/43 (55%)

Query: 223 WDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALH 265
           W+A    EL      +QRE E  +RQ+L+     ++++Q+ LH
Sbjct: 80  WEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLH 122


>gi|33342268 hypothetical protein LOC91300 [Homo sapiens]
          Length = 268

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 14/108 (12%)

Query: 119 RRGPGRGTSVRRRTSFYLPKDAVKHLH-----VLSRTR-AREVIEA----LLRKFLVVDD 168
           RRGPGRG   RR    Y P++  + +      VL R+R   E +E     LLR F V   
Sbjct: 147 RRGPGRGEDRRREDPAYTPRECFQRISRRLRAVLKRSRIPMETLETWEERLLRFFSVSPQ 206

Query: 169 PRKFAL----FERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFV 212
               A+    FER   H       L+     L  +     S++ L F+
Sbjct: 207 AVYTAMLDNSFERLLLHAVCQYMDLISASADLEGKRQMKVSNRHLDFL 254


>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
          Length = 1547

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%)

Query: 5    EAPSFEMTWSSTTSSGYCSQEDSDSELEQYFTARTSLARRPRRDQDEPVEWETPDLSQAE 64
            E PS   T S+ T+      E S S +E   T  TS ARR +    EP+   T D+  A 
Sbjct: 1369 EVPSSMTTESTATAM---QSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVAS 1425

Query: 65   IE 66
             E
Sbjct: 1426 AE 1427


>gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens]
          Length = 442

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%)

Query: 5   EAPSFEMTWSSTTSSGYCSQEDSDSELEQYFTARTSLARRPRRDQDEPVEWETPDLSQAE 64
           E PS   T S+ T+      E S S +E   T  TS ARR +    EP+   T D+  A 
Sbjct: 264 EVPSSMTTESTATAM---QSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVAS 320

Query: 65  IE 66
            E
Sbjct: 321 AE 322


>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
          Length = 1477

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%)

Query: 5    EAPSFEMTWSSTTSSGYCSQEDSDSELEQYFTARTSLARRPRRDQDEPVEWETPDLSQAE 64
            E PS   T S+ T+      E S S +E   T  TS ARR +    EP+   T D+  A 
Sbjct: 1299 EVPSSMTTESTATAM---QSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVAS 1355

Query: 65   IE 66
             E
Sbjct: 1356 AE 1357


>gi|4826870 nucleobindin 2 [Homo sapiens]
          Length = 420

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 14/45 (31%), Positives = 23/45 (51%)

Query: 28  DSELEQYFTARTSLARRPRRDQDEPVEWETPDLSQAEIEQKIKEY 72
           D+  ++  T    L    +++  EP  WET D  Q   E+++KEY
Sbjct: 306 DTNKDRLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTEEELKEY 350


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
           sapiens]
          Length = 3014

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 16/35 (45%), Positives = 19/35 (54%), Gaps = 4/35 (11%)

Query: 107 PSSKKPPSLQDARRGPG----RGTSVRRRTSFYLP 137
           PS   PP+L +AR GP     RGTS R    F +P
Sbjct: 214 PSPPLPPNLPEARAGPARRARRGTSGRGSLKFPMP 248


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 21/76 (27%), Positives = 29/76 (38%)

Query: 24  QEDSDSELEQYFTARTSLARRPRRDQDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMS 83
           Q D+D+ +  +F   +S       + DE +E E PD    E   K KE         F  
Sbjct: 556 QSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDSPGIEKHDKEKEQKDPKKLRSFKV 615

Query: 84  LNKDGSYTGFIKVQLK 99
            + D S     K  LK
Sbjct: 616 SSIDSSEQKKTKKNLK 631


>gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
          Length = 609

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 22/95 (23%), Positives = 37/95 (38%), Gaps = 11/95 (11%)

Query: 94  IKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGT-----------SVRRRTSFYLPKDAVK 142
           ++  L+  +P  VP + +P   Q       +GT            V      ++ +DAVK
Sbjct: 45  LRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVK 104

Query: 143 HLHVLSRTRAREVIEALLRKFLVVDDPRKFALFER 177
            L  + R   + V+        VVDD  K  L ++
Sbjct: 105 KLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQ 139


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,779,511
Number of Sequences: 37866
Number of extensions: 473526
Number of successful extensions: 1802
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 1765
Number of HSP's gapped (non-prelim): 51
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.