Search of human proteins with 25777647

Search of human proteins with 25777647

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25777647 small conductance calcium-activated potassium
channel protein 2 isoform b [Homo sapiens]
         (231 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25777647 small conductance calcium-activated potassium channe...   454   e-128
gi|25777645 small conductance calcium-activated potassium channe...   454   e-128
gi|25777650 small conductance calcium-activated potassium channe...   335   2e-92
gi|116805330 small conductance calcium-activated potassium chann...   335   2e-92
gi|25777643 potassium intermediate/small conductance calcium-act...   303   1e-82
gi|4504859 intermediate conductance calcium-activated potassium ...   187   5e-48
gi|236462242 potassium voltage-gated channel, KQT-like subfamily...    48   6e-06
gi|236462079 potassium voltage-gated channel, KQT-like subfamily...    44   9e-05
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,...    44   9e-05
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i...    42   6e-04
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i...    42   6e-04
gi|236461942 potassium voltage-gated channel, KQT-like subfamily...    40   0.001
gi|236461719 potassium voltage-gated channel, KQT-like subfamily...    40   0.001
gi|26051268 potassium voltage-gated channel KQT-like protein 2 i...    40   0.001
gi|26051260 potassium voltage-gated channel KQT-like protein 2 i...    40   0.001
gi|26051262 potassium voltage-gated channel KQT-like protein 2 i...    40   0.002
gi|26051264 potassium voltage-gated channel KQT-like protein 2 i...    40   0.002
gi|26051266 potassium voltage-gated channel KQT-like protein 2 i...    40   0.002
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H...    39   0.003
gi|32479525 potassium voltage-gated channel, KQT-like subfamily,...    38   0.006
gi|32479527 potassium voltage-gated channel, KQT-like subfamily,...    38   0.006
gi|27436981 potassium voltage-gated channel, Shal-related subfam...    38   0.008
gi|34486092 adenylate cyclase 5 [Homo sapiens]                         38   0.008
gi|4826784 potassium voltage-gated channel, Shab-related subfami...    37   0.011
gi|9789987 potassium voltage-gated channel, Shal-related subfami...    37   0.011
gi|27436984 potassium voltage-gated channel, Shal-related subfam...    37   0.011
gi|27436986 potassium voltage-gated channel, Shal-related subfam...    37   0.011
gi|27436974 potassium voltage-gated channel, Shab-related subfam...    37   0.011
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap...    37   0.014
gi|4826782 potassium voltage-gated channel, shaker-related subfa...    37   0.019

>gi|25777647 small conductance calcium-activated potassium channel
           protein 2 isoform b [Homo sapiens]
          Length = 231

 Score =  454 bits (1167), Expect = e-128
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN
Sbjct: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 120
           FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME
Sbjct: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 120

Query: 121 QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI 180
           QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI
Sbjct: 121 QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI 180

Query: 181 SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 231
           SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
Sbjct: 181 SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 231


>gi|25777645 small conductance calcium-activated potassium channel
           protein 2 isoform a [Homo sapiens]
          Length = 579

 Score =  454 bits (1167), Expect = e-128
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN
Sbjct: 349 MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 408

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 120
           FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME
Sbjct: 409 FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 468

Query: 121 QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI 180
           QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI
Sbjct: 469 QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI 528

Query: 181 SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 231
           SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
Sbjct: 529 SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 579


>gi|25777650 small conductance calcium-activated potassium channel
           protein 3 isoform b [Homo sapiens]
          Length = 426

 Score =  335 bits (859), Expect = 2e-92
 Identities = 172/231 (74%), Positives = 196/231 (84%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           MWLISITFLSIGYGDMVP+TYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN
Sbjct: 193 MWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 252

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 120
           FMMDTQLTKR+KNAAANVLRETWLIYK+TKL+KKIDHAKVRKHQRKFLQAIHQLRSVKME
Sbjct: 253 FMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKME 312

Query: 121 QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI 180
           QRKL+DQANTLVDL+K QN+MYD+I++LN+RSED EK+I +LE+KLE L  S ++LP LI
Sbjct: 313 QRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLI 372

Query: 181 SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 231
           + T+RQQQ+  + A +E+    V      +  S      SST+ PT   SS
Sbjct: 373 ADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSS 423


>gi|116805330 small conductance calcium-activated potassium channel
           protein 3 isoform a [Homo sapiens]
          Length = 731

 Score =  335 bits (859), Expect = 2e-92
 Identities = 172/231 (74%), Positives = 196/231 (84%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           MWLISITFLSIGYGDMVP+TYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN
Sbjct: 498 MWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 557

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 120
           FMMDTQLTKR+KNAAANVLRETWLIYK+TKL+KKIDHAKVRKHQRKFLQAIHQLRSVKME
Sbjct: 558 FMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKME 617

Query: 121 QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI 180
           QRKL+DQANTLVDL+K QN+MYD+I++LN+RSED EK+I +LE+KLE L  S ++LP LI
Sbjct: 618 QRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLI 677

Query: 181 SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 231
           + T+RQQQ+  + A +E+    V      +  S      SST+ PT   SS
Sbjct: 678 ADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSS 728


>gi|25777643 potassium intermediate/small conductance
           calcium-activated channel, subfamily N, member 1 [Homo
           sapiens]
          Length = 543

 Score =  303 bits (775), Expect = 1e-82
 Identities = 152/188 (80%), Positives = 170/188 (90%), Gaps = 3/188 (1%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           MWLISITFLSIGYGDMVP+TYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN
Sbjct: 321 MWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 380

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQ---LRSV 117
           FMMDTQLTKRVKNAAANVLRETWLIYK+T+LVKK D A+VRKHQRKFLQAIHQ   LRSV
Sbjct: 381 FMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQAQKLRSV 440

Query: 118 KMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALP 177
           K+EQ KLNDQANTL DLAKTQ +MYD++S+L+ + E+ E R+ TLE++L+ L  S+ ALP
Sbjct: 441 KIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLDALGASLQALP 500

Query: 178 GLISQTIR 185
           GLI+Q IR
Sbjct: 501 GLIAQAIR 508


>gi|4504859 intermediate conductance calcium-activated potassium
           channel protein 1 [Homo sapiens]
          Length = 427

 Score =  187 bits (476), Expect = 5e-48
 Identities = 95/169 (56%), Positives = 123/169 (72%), Gaps = 3/169 (1%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +WLI ITFL+IGYGD+VP T  GK VCL TG+MG  CTAL+VAVVARKLE  KAEKHVHN
Sbjct: 241 LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN 300

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 120
           FMMD Q TK +K +AA VL+E W+ YK+T+  +K  HA  R+HQRK L AI+  R V+++
Sbjct: 301 FMMDIQYTKEMKESAARVLQEAWMFYKHTR--RKESHA-ARRHQRKLLAAINAFRQVRLK 357

Query: 121 QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETL 169
            RKL +Q N++VD++K   I+YD+  +L+      EK+I TL  KL+ L
Sbjct: 358 HRKLREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDAL 406


>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 5 [Homo sapiens]
          Length = 822

 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 50/206 (24%), Positives = 91/206 (44%), Gaps = 25/206 (12%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W  +IT  +IGYGD  P T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 302 LWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQK 361

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 120
                   ++ +N AAN+++  W  Y   +  K +  A  + H    L+A+H     K E
Sbjct: 362 HF------EKRRNPAANLIQCVWRSYAADE--KSVSIATWKPH----LKALHTCSPTKKE 409

Query: 121 QRKLNDQANTL-VDLAKTQNIM-----YDMISDLNERSEDFEKRIVTLETKLETLIGSIH 174
           Q + + +     V   K +  +      D+I   +    D   RI +L+T+++ ++G   
Sbjct: 410 QGEASSRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGK-- 467

Query: 175 ALPGLISQTIRQQQRDFIEAQMESYD 200
              G I  T  ++ R+ I A+ E+ D
Sbjct: 468 ---GQI--TSDKKSREKITAEHETTD 488


>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 4 [Homo sapiens]
          Length = 951

 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 12/121 (9%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W  +IT  +IGYGD  P T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 302 LWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQK 361

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 120
                   ++ +N AAN+++  W  Y   +  K +  A  + H    L+A+H     K E
Sbjct: 362 HF------EKRRNPAANLIQCVWRSYAADE--KSVSIATWKPH----LKALHTCSPTKKE 409

Query: 121 Q 121
           Q
Sbjct: 410 Q 410


>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 1 [Homo sapiens]
          Length = 932

 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 12/121 (9%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W  +IT  +IGYGD  P T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 302 LWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQK 361

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 120
                   ++ +N AAN+++  W  Y   +  K +  A  + H    L+A+H     K E
Sbjct: 362 HF------EKRRNPAANLIQCVWRSYAADE--KSVSIATWKPH----LKALHTCSPTKKE 409

Query: 121 Q 121
           Q
Sbjct: 410 Q 410


>gi|26638655 potassium voltage-gated channel KQT-like protein 4
           isoform b [Homo sapiens]
          Length = 641

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 6/86 (6%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W  +IT  +IGYGD  P+T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 274 LWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQK 333

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIY 86
                   ++ +  AAN+++  W +Y
Sbjct: 334 HF------EKRRMPAANLIQAAWRLY 353


>gi|26638653 potassium voltage-gated channel KQT-like protein 4
           isoform a [Homo sapiens]
          Length = 695

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 6/86 (6%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W  +IT  +IGYGD  P+T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 274 LWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQK 333

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIY 86
                   ++ +  AAN+++  W +Y
Sbjct: 334 HF------EKRRMPAANLIQAAWRLY 353


>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 3 [Homo sapiens]
          Length = 942

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 12/112 (10%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W  +IT  +IGYGD  P T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 302 LWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQK 361

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIH 112
                   ++ +N AAN+++  W  Y   +  K +  A  + H    L+A+H
Sbjct: 362 HF------EKRRNPAANLIQCVWRSYAADE--KSVSIATWKPH----LKALH 401


>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 2 [Homo sapiens]
          Length = 923

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 12/112 (10%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W  +IT  +IGYGD  P T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 302 LWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQK 361

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIH 112
                   ++ +N AAN+++  W  Y   +  K +  A  + H    L+A+H
Sbjct: 362 HF------EKRRNPAANLIQCVWRSYAADE--KSVSIATWKPH----LKALH 401


>gi|26051268 potassium voltage-gated channel KQT-like protein 2
           isoform e [Homo sapiens]
          Length = 393

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 27/115 (23%), Positives = 51/115 (44%), Gaps = 7/115 (6%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W   IT  +IGYGD  P T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 268 LWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQK 327

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLR 115
                   ++ +N AA +++  W  Y  T L +   H+  + ++R     +++ R
Sbjct: 328 HF------EKRRNPAAGLIQSAWRFYA-TNLSRTDLHSTWQYYERTVTVPMYRYR 375


>gi|26051260 potassium voltage-gated channel KQT-like protein 2
           isoform c [Homo sapiens]
          Length = 844

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 7/114 (6%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W   IT  +IGYGD  P T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 268 LWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQK 327

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQL 114
                   ++ +N AA +++  W  Y  T L +   H+  + ++R     +++L
Sbjct: 328 HF------EKRRNPAAGLIQSAWRFYA-TNLSRTDLHSTWQYYERTVTVPMYRL 374


>gi|26051262 potassium voltage-gated channel KQT-like protein 2
           isoform b [Homo sapiens]
          Length = 854

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 7/105 (6%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W   IT  +IGYGD  P T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 268 LWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQK 327

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQR 105
                   ++ +N AA +++  W  Y  T L +   H+  + ++R
Sbjct: 328 HF------EKRRNPAAGLIQSAWRFYA-TNLSRTDLHSTWQYYER 365


>gi|26051264 potassium voltage-gated channel KQT-like protein 2
           isoform a [Homo sapiens]
          Length = 872

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 7/105 (6%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W   IT  +IGYGD  P T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 268 LWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQK 327

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQR 105
                   ++ +N AA +++  W  Y  T L +   H+  + ++R
Sbjct: 328 HF------EKRRNPAAGLIQSAWRFYA-TNLSRTDLHSTWQYYER 365


>gi|26051266 potassium voltage-gated channel KQT-like protein 2
           isoform d [Homo sapiens]
          Length = 841

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 7/105 (6%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W   IT  +IGYGD  P T+ G+ +     ++G    AL   ++     L   E+H   
Sbjct: 268 LWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQK 327

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQR 105
                   ++ +N AA +++  W  Y  T L +   H+  + ++R
Sbjct: 328 HF------EKRRNPAAGLIQSAWRFYA-TNLSRTDLHSTWQYYER 365


>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
           sapiens]
          Length = 872

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
           +W   IT  +IGYGD  P T+ G+ +     ++G    AL   ++   L L   E+H   
Sbjct: 307 LWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQK 366

Query: 61  FMMDTQLTKRVKNAAANVLRETWLIY 86
                   ++ +  AA +++  W  Y
Sbjct: 367 HF------EKRRKPAAELIQAAWRYY 386


>gi|32479525 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 2 [Homo sapiens]
          Length = 549

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 14/90 (15%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVV----ARKLELTKAEK 56
           +W   +T  +IGYGD VP T+ GK +     +      AL   ++    A K++  + +K
Sbjct: 176 LWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQK 235

Query: 57  HVHNFMMDTQLTKRVKNAAANVLRETWLIY 86
           H +          R   AAA++++  W  Y
Sbjct: 236 HFN----------RQIPAAASLIQTAWRCY 255


>gi|32479527 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 1 [Homo sapiens]
          Length = 676

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 14/90 (15%)

Query: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVV----ARKLELTKAEK 56
           +W   +T  +IGYGD VP T+ GK +     +      AL   ++    A K++  + +K
Sbjct: 303 LWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQK 362

Query: 57  HVHNFMMDTQLTKRVKNAAANVLRETWLIY 86
           H +          R   AAA++++  W  Y
Sbjct: 363 HFN----------RQIPAAASLIQTAWRCY 382


>gi|27436981 potassium voltage-gated channel, Shal-related
           subfamily, member 1 [Homo sapiens]
          Length = 647

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 15/35 (42%), Positives = 23/35 (65%), Gaps = 3/35 (8%)

Query: 2   WLISITFLSIGYGDMVPNTYCGK---GVCLLTGIM 33
           W   +T  ++GYGDMVP+T  GK    +C L+G++
Sbjct: 364 WYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVL 398


>gi|34486092 adenylate cyclase 5 [Homo sapiens]
          Length = 1261

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 27/125 (21%), Positives = 48/125 (38%), Gaps = 2/125 (1%)

Query: 84  LIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYD 143
           LI+  T +V    H      QR+  Q   +    ++  ++ N Q   L+     +++  +
Sbjct: 384 LIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAME 443

Query: 144 MISDLNERSED--FEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDK 201
           M +D+N + ED  F K  +     +  L   I     L SQ   Q+    +      +DK
Sbjct: 444 MKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDK 503

Query: 202 HVTYN 206
               N
Sbjct: 504 LAAEN 508


>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
           member 1 [Homo sapiens]
          Length = 858

 Score = 37.4 bits (85), Expect = 0.011
 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 7/75 (9%)

Query: 2   WLISITFLSIGYGDMVPNTYCGK---GVCLLTGIMGAGCTALVVAVVARKL-ELTKAEKH 57
           W  +IT  ++GYGD+ P T  GK   G+C + G++     AL + ++     E  K +K 
Sbjct: 369 WWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVL---VIALPIPIIVNNFSEFYKEQKR 425

Query: 58  VHNFMMDTQLTKRVK 72
               +   +  +R K
Sbjct: 426 QEKAIKRREALERAK 440


>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
           member 2 [Homo sapiens]
          Length = 630

 Score = 37.4 bits (85), Expect = 0.011
 Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 3/35 (8%)

Query: 2   WLISITFLSIGYGDMVPNTYCGK---GVCLLTGIM 33
           W   +T  ++GYGDMVP T  GK    +C L+G++
Sbjct: 362 WYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVL 396


>gi|27436984 potassium voltage-gated channel, Shal-related
           subfamily, member 3 isoform 1 [Homo sapiens]
          Length = 655

 Score = 37.4 bits (85), Expect = 0.011
 Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 3/35 (8%)

Query: 2   WLISITFLSIGYGDMVPNTYCGK---GVCLLTGIM 33
           W   +T  ++GYGDMVP T  GK    +C L+G++
Sbjct: 359 WYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVL 393


>gi|27436986 potassium voltage-gated channel, Shal-related
           subfamily, member 3 isoform 2 [Homo sapiens]
          Length = 636

 Score = 37.4 bits (85), Expect = 0.011
 Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 3/35 (8%)

Query: 2   WLISITFLSIGYGDMVPNTYCGK---GVCLLTGIM 33
           W   +T  ++GYGDMVP T  GK    +C L+G++
Sbjct: 359 WYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVL 393


>gi|27436974 potassium voltage-gated channel, Shab-related
           subfamily, member 2 [Homo sapiens]
          Length = 911

 Score = 37.4 bits (85), Expect = 0.011
 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 7/75 (9%)

Query: 2   WLISITFLSIGYGDMVPNTYCGK---GVCLLTGIMGAGCTALVVAVVARKL-ELTKAEKH 57
           W  +IT  ++GYGD+ P T  GK   G+C + G++     AL + ++     E  K +K 
Sbjct: 373 WWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVL---VIALPIPIIVNNFSEFYKEQKR 429

Query: 58  VHNFMMDTQLTKRVK 72
               +   +  +R K
Sbjct: 430 QEKAIKRREALERAK 444


>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
           sapiens]
          Length = 955

 Score = 37.0 bits (84), Expect = 0.014
 Identities = 37/190 (19%), Positives = 93/190 (48%), Gaps = 10/190 (5%)

Query: 44  VVARKLELTKAEKH-VHNFMMDTQLTKRVKNAAANVLRETWLIY--KNTKLVKKIDHAKV 100
           V AR+  L K + H V+++  + +L +   +A  N+L++   +   K + ++++++    
Sbjct: 455 VKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADINLLKQEHALSASKASSMIEELEQNVC 514

Query: 101 RKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIV 160
           +  Q+     + + + ++ ++ K   + + L  + + +   +D+ S+L++  ED +K+I 
Sbjct: 515 QLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKK--AHDLQSELDKGKEDTQKKIH 572

Query: 161 TLETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSS 220
             E  L+     +  +  +  Q ++ QQ D   A +E + + V  N+E+  +  + +   
Sbjct: 573 KFEEALKEKEEQLTRVTEV--QRLQAQQAD---AALEEFKRQVELNSEKVYAEMKEQMEK 627

Query: 221 STAPPTSSES 230
             A  T S+S
Sbjct: 628 VEADLTRSKS 637


>gi|4826782 potassium voltage-gated channel, shaker-related
           subfamily, member 2 [Homo sapiens]
          Length = 499

 Score = 36.6 bits (83), Expect = 0.019
 Identities = 19/44 (43%), Positives = 24/44 (54%)

Query: 2   WLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVV 45
           W   ++  ++GYGDMVP T  GK V  L  I G    AL V V+
Sbjct: 366 WWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVI 409


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.129    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,100,682
Number of Sequences: 37866
Number of extensions: 247354
Number of successful extensions: 1825
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 1651
Number of HSP's gapped (non-prelim): 259
length of query: 231
length of database: 18,247,518
effective HSP length: 99
effective length of query: 132
effective length of database: 14,498,784
effective search space: 1913839488
effective search space used: 1913839488
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.