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Search of human proteins with 253970427
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|253970427 immunoglobulin superfamily, member 22 [Homo
sapiens]
(1326 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens] 2662 0.0
gi|148839296 immunoglobulin-like and fibronectin type III domain... 579 e-165
gi|110349719 titin isoform N2-A [Homo sapiens] 423 e-118
gi|110349717 titin isoform novex-2 [Homo sapiens] 423 e-118
gi|110349713 titin isoform novex-1 [Homo sapiens] 423 e-118
gi|110349715 titin isoform N2-B [Homo sapiens] 423 e-118
gi|133908641 myosin binding protein C, fast type [Homo sapiens] 310 8e-84
gi|46049110 myosin binding protein C, slow type isoform 4 [Homo ... 303 6e-82
gi|46049125 myosin binding protein C, slow type isoform 2 [Homo ... 303 6e-82
gi|45976288 myosin binding protein C, slow type isoform 1 [Homo ... 303 6e-82
gi|46049119 myosin binding protein C, slow type isoform 3 [Homo ... 291 4e-78
gi|148596957 myosin binding protein C, cardiac [Homo sapiens] 278 2e-74
gi|110349721 titin isoform novex-3 [Homo sapiens] 201 3e-51
gi|140560917 myomesin 1 isoform b [Homo sapiens] 190 7e-48
gi|55956914 myosin binding protein H [Homo sapiens] 186 1e-46
gi|140560919 myomesin 1 isoform a [Homo sapiens] 170 7e-42
gi|156104903 myomesin 2 [Homo sapiens] 168 3e-41
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 165 3e-40
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 165 3e-40
gi|155969693 myomesin family, member 3 [Homo sapiens] 164 7e-40
gi|144226847 obscurin-like 1 [Homo sapiens] 145 3e-34
gi|194018539 myosin binding protein H-like [Homo sapiens] 127 5e-29
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 123 1e-27
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 123 1e-27
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 121 4e-27
gi|83281200 protogenin [Homo sapiens] 120 7e-27
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 120 1e-26
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 119 1e-26
gi|157311649 neogenin homolog 1 [Homo sapiens] 112 2e-24
gi|7657361 contactin 6 [Homo sapiens] 109 2e-23
>gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens]
Length = 1326
Score = 2662 bits (6900), Expect = 0.0
Identities = 1326/1326 (100%), Positives = 1326/1326 (100%)
Query: 1 MTTIHSRQMLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNI 60
MTTIHSRQMLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNI
Sbjct: 1 MTTIHSRQMLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNI 60
Query: 61 PAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSIN 120
PAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSIN
Sbjct: 61 PAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSIN 120
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK 180
KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK
Sbjct: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK 180
Query: 181 KQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPL 240
KQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPL
Sbjct: 181 KQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPL 240
Query: 241 EDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNV 300
EDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNV
Sbjct: 241 EDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNV 300
Query: 301 NMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVW 360
NMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVW
Sbjct: 301 NMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVW 360
Query: 361 KFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIK 420
KFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIK
Sbjct: 361 KFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIK 420
Query: 421 FVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDA 480
FVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDA
Sbjct: 421 FVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDA 480
Query: 481 QLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDE 540
QLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDE
Sbjct: 481 QLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDE 540
Query: 541 KVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIAD 600
KVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIAD
Sbjct: 541 KVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIAD 600
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE
Sbjct: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHM 720
DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHM
Sbjct: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHM 720
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN
Sbjct: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
Query: 781 SEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVER 840
SEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVER
Sbjct: 781 SEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVER 840
Query: 841 RKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPV 900
RKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPV
Sbjct: 841 RKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPV 900
Query: 901 KPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCY 960
KPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCY
Sbjct: 901 KPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCY 960
Query: 961 TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGT 1020
TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGT
Sbjct: 961 TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGT 1020
Query: 1021 ALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNE 1080
ALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNE
Sbjct: 1021 ALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNE 1080
Query: 1081 FGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTA 1140
FGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTA
Sbjct: 1081 FGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTA 1140
Query: 1141 TWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAK 1200
TWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAK
Sbjct: 1141 TWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAK 1200
Query: 1201 LKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFW 1260
LKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFW
Sbjct: 1201 LKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFW 1260
Query: 1261 YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQK 1320
YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQK
Sbjct: 1261 YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQK 1320
Query: 1321 KSKHLM 1326
KSKHLM
Sbjct: 1321 KSKHLM 1326
>gi|148839296 immunoglobulin-like and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 868
Score = 579 bits (1492), Expect = e-165
Identities = 301/791 (38%), Positives = 447/791 (56%), Gaps = 8/791 (1%)
Query: 519 GMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPE 578
G++D+ G A L L + G W KDG ++T G+ + G VH L +
Sbjct: 78 GLADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGT 137
Query: 579 HEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPK 638
G+YTF A +SEA++ + D PTI P V E L + VK G +K+PF+ +
Sbjct: 138 QAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLR-EPLVVKAGKPVIVKIPFQSHLPIQ 196
Query: 639 VTWYKDGMEV--TEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLS 696
W KDG EV + + ++ G+ L + + R+D G + L+++ GS A L L
Sbjct: 197 AAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQ 256
Query: 697 VLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDG 756
V+D+P PPQG +E + + V ++W+ P+DNGGR V ++VERR G+ +W+K+GE
Sbjct: 257 VIDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPA 316
Query: 757 KVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKE 816
T F+ VE G+ Y FR+ AV SEG + LE+EE+ P P S P + + +
Sbjct: 317 DSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVA-PEALPKAPSAPAILSASSQ 375
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
+T+TW AP G A +LGY++ERRKKGSN W VN P+ + TV + + +YEFRV
Sbjct: 376 GITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRV 435
Query: 877 IAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPPSG 934
AV +GPG+P PS +V A+DP++PPGLV++L V+D SN+SI+L+W P EGD G
Sbjct: 436 TAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQG 495
Query: 935 YILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVR 994
Y++E+ + D+ +W C + T YT GL + YF R+ AVNE G +P LD V+
Sbjct: 496 YVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQ 555
Query: 995 AMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKS 1054
AMP PKF + + K + V+ G + + +F P P+V W KDG+P R
Sbjct: 556 AMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPEVTWLKDGLPLPKRSVTVTK 615
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFG-EARYDIHVRVADFPRPPTNLRLFEEVPNTVT 1113
+Q LI SDSG+Y ++L+ G E + +RVA P+ P + L E VP TVT
Sbjct: 616 DGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVAHSFRIRVAACPQAPGPIHLQENVPGTVT 675
Query: 1114 LTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARN 1173
W SPD +D HY + R ++ W+ AA+R+ +N++T+ G+LPG +Y+FRVVA+N
Sbjct: 676 AEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAADRIHTNRFTLLGILPGHEYHFRVVAKN 735
Query: 1174 EIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMT 1233
E+G S+P D+ W I + Q + K Y + D PRF+ L+ H + +G +C M+
Sbjct: 736 ELGASKPSDTSQPWCIPR-QRDRFTVKAPCYREPDLSQKPRFLVGLRSHLLPQGCECCMS 794
Query: 1234 CAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGK 1293
CA G+PRP VT +K D ++ N + GVC+L IP+ + KDSG+Y + EN LG+
Sbjct: 795 CAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENTLGQ 854
Query: 1294 DRSSCTLTVYD 1304
S+ TL V +
Sbjct: 855 AVSTATLIVIE 865
Score = 137 bits (346), Expect = 5e-32
Identities = 137/551 (24%), Positives = 214/551 (38%), Gaps = 50/551 (9%)
Query: 389 KDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVT 448
+DA S + + G+ + AQ + F L ++ V+ A L C LTS
Sbjct: 47 RDATRSSTSRYKPGTGSFSKDAQGPMGH----FSQGLADMEVQPGEAATLSCTLTSDLGP 102
Query: 449 LRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVT 508
W KDG L +G L I Q + G YT VA GD S A +T
Sbjct: 103 GTWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQAGRYTFVA---GD---QQSEATLT 156
Query: 509 VEERLATVKSGMSD-----VHAATGSPAELCVVLNDE-KVEGVWLKDGKEITDLPG--MQ 560
V++ T+ +++ + G P + + ++ W KDG E+ Q
Sbjct: 157 VQDS-PTIAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAAWRKDGAEVVGSSDREAQ 215
Query: 561 IVKQGAVHKLIFPSMGPEHEGKY--TFRAKG--TESEASVFIADPPTIDPSVLEALAAHA 616
+ +L PS G + G+Y T R++G ++E ++ + D P +E H
Sbjct: 216 VDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPMEVQDCHR 275
Query: 617 ITVKV---------GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
V + G T V R + + TW K G E D T
Sbjct: 276 AGVCLRWRPPRDNGGRTVECYVVER-RQAGRSTWLKVG-----------EAPADSTTFTD 323
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHLSVL----DRPKPPQGRVEFLELSGSCVHMKWK 723
++ ++ G+ A +L PK P L S + + W
Sbjct: 324 AHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPA-ILSASSQGITLTWT 382
Query: 724 APKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEG 783
AP+ G + +++ERR G +W + + ++ V +G Y+FR+ AV G
Sbjct: 383 APRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRVTAVAPSG 442
Query: 784 VSDP-LETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRK 842
+P ++ VFA +P+ PPG QVTD + ++T++W P G GY+VE
Sbjct: 443 PGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCS 502
Query: 843 KGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKP 902
S W+P + + T T GL Y RV AVN+ G QPS + V A
Sbjct: 503 SDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQAMPVTVC 562
Query: 903 PGLVQDLHVSD 913
P + D D
Sbjct: 563 PKFLVDSSTKD 573
Score = 91.7 bits (226), Expect = 4e-18
Identities = 164/784 (20%), Positives = 276/784 (35%), Gaps = 92/784 (11%)
Query: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPI 419
W +G +L D + +DGL H+L I + + +G ++ AG+ +A LT+ P
Sbjct: 105 WFKDGVKLTTQDG--VIFKQDGLVHSLFITHVQGTQAGRYTFVAGDQQSEATLTVQDSPT 162
Query: 420 KFVSNLKNVR----VKERSRACLECELTSK-DVTLRWKKDGQLLMHGT--KYSMNHEGKR 472
+ +R VK ++ S + W+KDG ++ + + ++
Sbjct: 163 IAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAAWRKDGAEVVGSSDREAQVDLGDGY 222
Query: 473 AELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA------ 526
L + A D G+Y+V +G + T V + + D H A
Sbjct: 223 TRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPMEVQDCHRAGVCLRW 282
Query: 527 ------TGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHE 580
G E VV + WLK G+ D F E
Sbjct: 283 RPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPAD-------------STTFTDAHVEPG 329
Query: 581 GKYTFRAKGTES-------EASVFIADPPTID-----PSVLEALAAHAITV-----KVGH 623
KYTFR + S E+ + P + P++L A ++ IT+ +
Sbjct: 330 RKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAILSA-SSQGITLTWTAPRGPG 388
Query: 624 TAHI-KVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKL 682
+AHI + TW + E R ++ SG
Sbjct: 389 SAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRVTAVAPSG------ 442
Query: 683 KNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRA 742
+ G + + RP ++ + S + + + W P G ++VE +
Sbjct: 443 PGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCS 502
Query: 743 VGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP- 801
W+ VT ++ + G+ Y R+ AVN G S P + + P+
Sbjct: 503 SDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQAMPVTVC 562
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNL---WVPVNKDPIQG 858
P F D+ V T P P+ V K G L V V KD +
Sbjct: 563 PKFLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPE--VTWLKDGLPLPKRSVTVTKDGLTQ 620
Query: 859 TKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSS 918
V GL + Y V + G+ S + + PG +H+ ++ +
Sbjct: 621 LLIPVAGLSDSGLY----TVVLRTLQGKEVAHSFRIRVAACPQAPG---PIHLQENVPGT 673
Query: 919 ISLAWR-EPAEG-DPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIR 976
++ W P E D P Y + R+ W + I +T+ G++ +Y FR+
Sbjct: 674 VTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAAD-RIHTNRFTLLGILPGHEYHFRVV 732
Query: 977 AVNEAGVGEP--------VELDKGVRAMPPPAAPKFDLSAR------LKSHMVVRAGTAL 1022
A NE G +P + + + P + DLS + L+SH++ + G
Sbjct: 733 AKNELGASKPSDTSQPWCIPRQRDRFTVKAPCYREPDLSQKPRFLVGLRSHLLPQ-GCEC 791
Query: 1023 CIHAAFSGSPPPDVIWQKDGVPTKGRETI--TKSKNHSQFLINSTKRSDSGVYRILLQNE 1080
C+ A GSP P V W K+ +G + T I S DSG Y+ + +N
Sbjct: 792 CMSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENT 851
Query: 1081 FGEA 1084
G+A
Sbjct: 852 LGQA 855
Score = 40.8 bits (94), Expect = 0.009
Identities = 22/93 (23%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P F+ + P+G + VQG+ +PH++W + ++ + ++ + L
Sbjct: 774 PRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDR-SLEGNPAVYSTDLLGVCSLT 832
Query: 127 LEPLTSDDSDNYKCIASNDHADAIYTVSLLVTE 159
+ ++ DS YK +A N A+ T +L+V E
Sbjct: 833 IPSVSPKDSGEYKAVAENTLGQAVSTATLIVIE 865
Score = 38.1 bits (87), Expect = 0.056
Identities = 42/143 (29%), Positives = 65/143 (45%), Gaps = 17/143 (11%)
Query: 287 KQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEP------LKFLGEMKPVKVT 340
KQ G + L I++V AG Y+ GD++ A LTV D P + L E P+ V
Sbjct: 121 KQDGLVHSLFITHVQGTQAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLRE--PLVVK 178
Query: 341 ERQTAVFEIRLSKKEP-NFVWKFNGKELKRDDKYEITVS-EDGLTHTLKIKDARLSDSGE 398
+ + +I P W+ +G E+ E V DG T L + A D G+
Sbjct: 179 AGKPVIVKIPFQSHLPIQAAWRKDGAEVVGSSDREAQVDLGDGYTR-LCLPSAGRKDCGQ 237
Query: 399 FS----AEAGNLVQKAQLTIDRI 417
+S +E G++ +A+LT+ I
Sbjct: 238 YSVTLRSEGGSV--QAELTLQVI 258
Score = 33.9 bits (76), Expect = 1.1
Identities = 17/42 (40%), Positives = 23/42 (54%)
Query: 1266 GVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
G L +P+ KD G YSV + +E G ++ TL V DK D
Sbjct: 221 GYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPD 262
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 423 bits (1087), Expect = e-118
Identities = 299/1086 (27%), Positives = 497/1086 (45%), Gaps = 54/1086 (4%)
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTV------------SLLVTEGQEKMDFKK 168
++ +L ++ +D+ NY C + D V +L + EG EK +F
Sbjct: 12515 RKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEG-EKAEFVC 12573
Query: 169 MLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDF---EKVCMEYG-FTDFRGLLRKLKE 224
+ K + P K+ K + ++++ K+ + + G + G R
Sbjct: 12574 SISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAH 12633
Query: 225 MKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKY 284
+ +E +RI+ PL+D K VVF+C E+ K W + E + + KY
Sbjct: 12634 L---TVIEKLRIVVPLKDTRVKEQQEVVFNC--EVNTEGAKAKWFRNEEAI---FDSSKY 12685
Query: 285 DVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR-----MSAELTVLDEPLKFLGEMKPVKV 339
+ Q Y L I + +++D Y++S+ + R +A L V +E L+ + +K ++
Sbjct: 12686 IILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIET 12745
Query: 340 TERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEF 399
E+++ F ++++ W NG+E+ D++ V D H L IKD D GE+
Sbjct: 12746 MEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRV--DKYKHMLTIKDCGFPDEGEY 12803
Query: 400 SAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLM 459
AG A+L I P +FV +L++ V E A C+L+ + ++W ++G+ +
Sbjct: 12804 IVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIK 12863
Query: 460 HGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSG 519
G KY +G LII+D +L D EY ++D S A + VEE +
Sbjct: 12864 EGKKYKFEKDGSIHRLIIKDCRLDDECEYAC-GVEDRK-----SRARLFVEEIPVEIIRP 12917
Query: 520 MSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEH 579
D+ A G+ LN +KVE WL++ + Q++ +G +H+L + P
Sbjct: 12918 PQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRD 12977
Query: 580 EGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKV 639
+G+Y F AK E+ A + +A P I A + V VG + VP+ P +
Sbjct: 12978 QGEYRFIAKDKEARAKLELAAAPKIKT------ADQDLVVDVGKPLTMVVPYDAYPKAEA 13031
Query: 640 TWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLD 699
W+K+ ++ + +++ +Q I + D G + L+N HG A ++L V+D
Sbjct: 13032 EWFKENEPLSTK---TIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVID 13088
Query: 700 RPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVT 759
P P + +E E V + W+ P +GG + ++VERR + +K+W+ +
Sbjct: 13089 VPGPVRN-LEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE 13147
Query: 760 NFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAV 818
T + G Y FR+ A N G +P+ET+ V A + + PG +TDV + V
Sbjct: 13148 FTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGV 13207
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
++TW P DGGA + Y++E R K S W + TV ++E EY FRV A
Sbjct: 13208 SLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRA 13267
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYI 936
N+ G G+PS + V DP++ P +L SD + SS+ L W P + G P GYI
Sbjct: 13268 QNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 13327
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
+E E W +C + Y V GL + KY +R+ A N+AGV +P E+ + A
Sbjct: 13328 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 13387
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIW--QKDGVPTKGRETITKS 1054
P DLSA K + V + I +G P P W + T R +
Sbjct: 13388 DAFVEPTMDLSA-FKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTL 13446
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+++ +I+ ++RSD G+Y + L+N +I V V P P L+ + ++V L
Sbjct: 13447 SAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHL 13506
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNE 1174
TW D Y++ KR+ S TW + V ++TV L+ G++Y F+V ARN+
Sbjct: 13507 TWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNK 13566
Query: 1175 IGDSEP 1180
G EP
Sbjct: 13567 CGPGEP 13572
Score = 380 bits (977), Expect = e-105
Identities = 300/1056 (28%), Positives = 483/1056 (45%), Gaps = 93/1056 (8%)
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+MG KY ++ VN+ YS S+ + + + D L+ ++K VT R A
Sbjct: 29408 KMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD--LELADDLKKT-VTIRAGASL 29464
Query: 348 EIRLS---KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKD-ARLSDSGEFSAEA 403
+ +S + P W G +L + T S ++L I D D+G+++ EA
Sbjct: 29465 RLMVSVSGRPPPVITWSKQGIDLASRAIIDTTES-----YSLLIVDKVNRYDAGKYTIEA 29519
Query: 404 GNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWK---KDGQLLMH 460
N K T+ +V+VKE SR VT+ W+ DG ++
Sbjct: 29520 ENQSGKKSATVLVKVYDTPGPCPSVKVKEVSR---------DSVTITWEIPTIDGGAPVN 29570
Query: 461 GTKYSMNHEGKRA---------ELIIEDAQLSDGGEYTVVAMQD-----GDPTEYYSTAI 506
RA + + + L +G Y + + G+P E S A+
Sbjct: 29571 NYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE-TSDAV 29629
Query: 507 VTVEERLATVKSGMSDVHAATGSPA-ELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQG 565
+ E L K + DV +T + A E + ++ G L+ K T+ + +
Sbjct: 29630 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 29689
Query: 566 AVHKLIFPSMGPEHEGKYTFRAKG-------TESEASVFIAD---PPTIDPSVLEALAAH 615
V + S+ + + RA+ E+ +V + D PTID S + H
Sbjct: 29690 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIH 29749
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDS 675
V G + +P G+P P +W+ G ++ E ERV++E A LTI D+
Sbjct: 29750 ---VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 29806
Query: 676 GLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQ 735
G L+LKN G+ + T+ + +LD+P PP G ++ E+ + + + W+ P+ +GG P++
Sbjct: 29807 GEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSG 29866
Query: 736 FIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFA 795
++VE+R + W+ + E + T F ++ EG Y FR+ A N G+ L++E +
Sbjct: 29867 YVVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIEC 29925
Query: 796 GNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP 855
+ I PG Q+ DV+++ +T+TW P DGG+ V GYIVER++ ++ WV VNK P
Sbjct: 29926 RSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVP 29985
Query: 856 IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSS 915
+ T+ GL E EYE RV A+N G G+PS PS +VA DP+ PPG Q+ V+D++
Sbjct: 29986 VTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTT 30045
Query: 916 NSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFF 973
+S+SLAW P + G +GY++EM+ D EW+KC P YT+ L + +Y F
Sbjct: 30046 RTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRF 30105
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
R+ A N G GEP E+ V+ P ++L R + + VR G + + G P
Sbjct: 30106 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPF 30165
Query: 1034 PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVA 1093
P W K+G R I S+ H++ +I R DSG Y ++L+N+ G+ I VRV
Sbjct: 30166 PICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVI 30225
Query: 1094 DFPRPPTNLRLFEEVP-NTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERV 1149
P P ++++ +V ++W D DG A YI+ +R+ A WYT RV
Sbjct: 30226 GSPNSPEGPLEYDDIQVRSVRVSWRPPAD---DGGADILGYILERREVPKAAWYTIDSRV 30282
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
V GL +Y+FRV A N+ G S+PL S + P K
Sbjct: 30283 RGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE-----------------PVTPKTP 30325
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP------TVTLYKGDVNITANSKFWYNS 1263
+ P P P VL D T + L RP VT Y + T+ K+ ++
Sbjct: 30326 LNPPE--PPSNPPEVL---DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHN 30380
Query: 1264 TSGVCTLVIPTCTLKDSGDYS--VLVENELGKDRSS 1297
+ + T + L +Y ++ +N++G +S
Sbjct: 30381 KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETS 30416
Score = 377 bits (967), Expect = e-104
Identities = 245/766 (31%), Positives = 380/766 (49%), Gaps = 52/766 (6%)
Query: 448 TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIV 507
+L W K L+ T+Y + E L+ G + PTEY
Sbjct: 19135 SLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG-----SSPPSKPTEY------ 19183
Query: 508 TVEERLATVKSGMSDVHAATGSPAELCVVL----NDEKVEGVWLKDGKEITDLPGMQIVK 563
V R+ G +V T S L K+ G ++ E LPG + V+
Sbjct: 19184 -VTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFV----EACKLPGDKWVR 19238
Query: 564 -QGAVHKLI---FPSMGPEHEGKYTFRA----------KGTESEASVFIAD--PPTIDPS 607
A H++ + + G E + +Y FRA S+ +A+ PP ID S
Sbjct: 19239 CNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS 19298
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
V +TVK G + GKP+P V+W KDG + E + M + L +
Sbjct: 19299 VA---MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLEL 19355
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKD 727
+ R+DSG + +N GS +AT+ L VLD+P PP V+ ++ + W+ P +
Sbjct: 19356 FSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPAS-VKINKMYSDRAMLSWEPPLE 19414
Query: 728 NGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP 787
+GG +T +IV++R + +W ++ +T+ S K+ EG YQFRI A N GV DP
Sbjct: 19415 DGGSEITNYIVDKRETSRPNWAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDP 19473
Query: 788 LETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNL 847
+ TE A NP +PPG P ++++TK+ +T++W P DGG+P+ GY++E+R+ +
Sbjct: 19474 VFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVN 19533
Query: 848 WVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
W VN+ PI GL E TEYEFRV A+NKAGPG+PS S + A+DP PPG
Sbjct: 19534 WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPA 19593
Query: 908 DLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIP--ISGTCYTVG 963
V D++ SS+SL+W +PA G P GY++E++ D+ W +C +P + T + V
Sbjct: 19594 FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRC-NLPQNLQKTRFEVT 19652
Query: 964 GLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC 1023
GL+E +Y FR+ AVN+ G +P ++ P+ +L A L+ +++RAG +
Sbjct: 19653 GLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMR 19712
Query: 1024 IHAAFSGSPPPDVIWQKDGVPTKGRETI-TKSKNHSQFL-INSTKRSDSGVYRILLQNEF 1081
++ G PPP + W K V + R + KS + FL + + D+G Y + L+N
Sbjct: 19713 LYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSC 19772
Query: 1082 GEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDAST 1139
G+ Y I V+V D P PP N+ + E ++ +TW P + + G +Y++ KRDA
Sbjct: 19773 GKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTW--EPPIIDGGSPIINYVVQKRDAER 19830
Query: 1140 ATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+W T + V L G+ Y+FRV A NE G +P ++RD
Sbjct: 19831 KSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRD 19876
Score = 372 bits (954), Expect = e-102
Identities = 280/973 (28%), Positives = 457/973 (46%), Gaps = 72/973 (7%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRM 317
P + W+K EPL+ + +V++ T +L I N +D G Y++ S G
Sbjct: 24339 PRPNISWVKDGEPLK---QTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATE 24395
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVW--KFNGKELKRDDKYEI 375
+ + VL++P +G PV+ E +A F + +S + P + + + +++ D
Sbjct: 24396 NLSVIVLEKPGPPVG---PVRFDE-VSADFVV-ISWEPPAYTGGCQISNYIVEKRDTTTT 24450
Query: 376 T---VSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKA-----QLTIDRIPIK------- 420
T VS T+KI + +F A N K+ + I + P K
Sbjct: 24451 TWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGT 24510
Query: 421 -FVSNLKNVR--------VKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMN--H 468
FV+++ + V + + L K+ ++ W K + + TK+
Sbjct: 24511 PFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLD 24570
Query: 469 EGKRAELIIEDAQLSDGGEYT-----VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
EG E + + G+ + VA DP ++T K D
Sbjct: 24571 EGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYD- 24629
Query: 524 HAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVH--KLIFPSMGPEHEG 581
GS +V + +G W+K T++ + G V + F + G
Sbjct: 24630 ---GGSKITGYIVEKKDLPDGRWMK--ASFTNVLETEFTVSGLVEDQRYEFRVIARNAAG 24684
Query: 582 KYTFRAKGTESEASVFIADPP--TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKV 639
++ + + + + D P ++DP + + HA G T ++ RGKP+P V
Sbjct: 24685 NFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA-----GETFVLEADIRGKPIPDV 24739
Query: 640 TWYKDGMEVTEEE-RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVL 698
W KDG E+ E R+ ++ + L + +C+R D G +LKL N G+ + + + VL
Sbjct: 24740 VWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVL 24799
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
DRP PP+G ++ ++ ++ W P +GG ++ +I+E+R + SW ++ + +
Sbjct: 24800 DRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVS-TEVQA 24858
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAV 818
N+ K+ G Y FR++AVN G+ +PLE+ V A NP +PPG S P+V+ +TK+++
Sbjct: 24859 LNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSM 24918
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
+TW P DGG + GYI+E+R K W NK + + V GL E YEFRV A
Sbjct: 24919 VVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAA 24978
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYI 936
N AG G+PS PS A D + PPG + V+D+S SS+SLAW +P G P GY+
Sbjct: 24979 ENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYV 25038
Query: 937 LEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRA 995
+E++ EW+ CT + G +TV L E +Y FRI A+N GVGEP L V A
Sbjct: 25039 VEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVA 25098
Query: 996 MPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKGRETITKS 1054
P+ +L A L+ +V+RA L + G P P+V W+K +G+ T R I +
Sbjct: 25099 QERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT-DRAQIEVT 25157
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+ + +I++ R DSG Y + L+N G ++VRV D P P NL + E ++VTL
Sbjct: 25158 SSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTL 25217
Query: 1115 TWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVAR 1172
+W P + + G +YI+ KR+ + + T + + L G YYFRV+A
Sbjct: 25218 SW--EPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLAS 25275
Query: 1173 NEIGDSEPLDSRD 1185
NE G P ++ +
Sbjct: 25276 NEYGIGLPAETTE 25288
Score = 369 bits (946), Expect = e-101
Identities = 203/577 (35%), Positives = 321/577 (55%), Gaps = 11/577 (1%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ + G + ++ GKP P + WYKD E+ V +E D A + I + R +SG
Sbjct: 26882 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 26941
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
LKL+N GSA+AT+ + +LD+P PP G +EF ++ + + W+ P D+GG +T +
Sbjct: 26942 CYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHY 27001
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
IVE+R + W + E + +T K+ +G Y FR+ AVN G+ +PLE++ V A
Sbjct: 27002 IVEKRETSRVVWSMVSEHLEECI-ITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAK 27060
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N PG P+VT +TK ++T+ W+ P DGG+ + GY +E+R K S W V K+ I
Sbjct: 27061 NAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETI 27120
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ T+ V GL E+++Y++RV AVN AG G S PS A DP+ PPG + ++DS+
Sbjct: 27121 RDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 27180
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSK-CTKIPISGTCYTVGGLIERQKYFF 973
SSI+L W +P G +GY++E+R + +EW+ TK + T Y V L Y+F
Sbjct: 27181 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 27240
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
R+ AVN AG GEP+E+++ V+A AP+ DL L++ ++ +AG + + F G PP
Sbjct: 27241 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPP 27300
Query: 1034 PDVIWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYD-IHV 1090
P V W+KD + + R +I + + S I R+D+G Y + ++N GE + + V
Sbjct: 27301 PTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSV 27360
Query: 1091 RVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAER 1148
+V D P L++ TVTL W+ P + + G +Y+I KRDA+ TW + +
Sbjct: 27361 KVLDTPAACQKLQVKHVSRGTVTLLWD--PPLIDGGSPIINYVIEKRDATKRTWSVVSHK 27418
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
S + + L ++FRV+A NEIG EP ++ +
Sbjct: 27419 CSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTE 27455
Score = 361 bits (927), Expect = 2e-99
Identities = 200/602 (33%), Positives = 315/602 (52%), Gaps = 12/602 (1%)
Query: 590 TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVT 649
+ES + + D +++ I VK G I G+PLP ++W KDG+E+
Sbjct: 25772 SESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE 25831
Query: 650 EEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVE 709
E R + ++ LLT+ +C+R D+G +L LKN G+ + ++ VLD+P PP G +E
Sbjct: 25832 ERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLE 25891
Query: 710 FLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEG 769
L+ + W P+++GG + +IVE+R +W I E + ++T+ K+ +G
Sbjct: 25892 INGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT-ICEGELQMTSCKVTKLLKG 25950
Query: 770 KAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDG 829
Y FR+ VN GV +PLE+ + A +P P + ++T VTKE++T+ W+ P DG
Sbjct: 25951 NEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDG 26010
Query: 830 GAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSV 889
G+ + GYI+ERR+K S WV VNK P+ + GL E EYE+RV A N AG PS
Sbjct: 26011 GSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSE 26070
Query: 890 PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEW 947
S + A+DPV P + DS ++I++AW +P G P +GY +E + D +W
Sbjct: 26071 TSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW 26130
Query: 948 SKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLS 1007
K + + GT YT+ GL +Y FR+++VN+ G +P + A P FD+
Sbjct: 26131 -KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDID 26189
Query: 1008 ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKR 1067
+ ++ ++V+AG + + F G P P+V+W K + R + + + + I + R
Sbjct: 26190 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANR 26249
Query: 1068 SDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQE-DG 1126
+DSG Y + +QN A + V+V D P PPTN+ + + + L+W DV E DG
Sbjct: 26250 NDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSW----DVPENDG 26305
Query: 1127 EA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
A +Y I KR+AS W + Y VT L G YYFRV NE G P ++
Sbjct: 26306 GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAET 26365
Query: 1184 RD 1185
++
Sbjct: 26366 KE 26367
Score = 358 bits (918), Expect = 2e-98
Identities = 222/650 (34%), Positives = 334/650 (51%), Gaps = 19/650 (2%)
Query: 552 EITDLPGMQIVKQGAVH--KLIFPSMGPEHEGKYTFR--AKGT--------ESEASVFIA 599
E DLP +K V+ + F GKY FR AK T ES ++
Sbjct: 20311 EKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICK 20370
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIK-VPFRGKPLPKVTWYKDGMEVTEEERVSMER 658
D VL+ +T+K G T + + GKPLPK +W K G ++ + +
Sbjct: 20371 DEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITS 20430
Query: 659 GEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCV 718
++LTI R+D+G + N G+ + ++VLD P PP G VE +S
Sbjct: 20431 TPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKA 20489
Query: 719 HMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILA 778
+ W P ++GG P+ +I+E+R + W + E D + K+ +G Y FR+ A
Sbjct: 20490 TLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSE-DIQSCRHVATKLIQGNEYIFRVSA 20548
Query: 779 VNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
VN G +P+++E V + PPG +P+V++VTK T++W P DGG+ + GY V
Sbjct: 20549 VNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 20608
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
ERR+K S WV K P+ +C V GL E + YEFRV A N+AG G PS S SV+ KD
Sbjct: 20609 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 20668
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPPSGYILEMRAEDTKEWSK-CTKIPI 955
PPG + HV+D++ S SLAW +P G +GY++E + + W K T +
Sbjct: 20669 AAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTAL 20728
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
T + V L ++KY FRI A+N+AGVGEP + V + AP F+L A L+ +V
Sbjct: 20729 RITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI-PDVEIVEREMAPDFELDAELRRTLV 20787
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
VRAG ++ I G P P+V W KD + K R I +++ + +I R D+G + +
Sbjct: 20788 VRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 20847
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
++N G+ ++VRV D P P NLR + ++VTL W+ +YI+ KR
Sbjct: 20848 TIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKR 20907
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+A+ ++ TA + Y VTGL G +Y+FRV+A NE G EP ++ +
Sbjct: 20908 EATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTE 20957
Score = 355 bits (910), Expect = 2e-97
Identities = 278/985 (28%), Positives = 444/985 (45%), Gaps = 97/985 (9%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P + W K PL+ + D + T L I + +D G Y ++V G K
Sbjct: 23257 PKPTITWTKDGLPLKQTTRINVTDSLDLTT---LSIKETHKDDGGQYGITVANVVGQKTA 23313
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKF---NGKELKRDDKYE 374
S E+ LD+P G PVK + + I LS P + N KRD
Sbjct: 23314 SIEIVTLDKPDPPKG---PVKFDD--VSAESITLSWNPPLYTGGCQITNYIVQKRDTTTT 23368
Query: 375 I--TVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV-QKAQLTIDRIPIKF---------- 421
+ VS TLK+ + +F A N Q L D I ++
Sbjct: 23369 VWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGT 23428
Query: 422 -----VSNLKNV-----RVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEG 470
+S V V + L K+ ++ W K + ++H T++ +
Sbjct: 23429 PFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQN-- 23486
Query: 471 KRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMS-DVHAATGS 529
L +G EY Y+ IV V + + ++ D G+
Sbjct: 23487 -----------LEEGIEYEF---------RVYAENIVGVGKASKNSECYVARDPCDPPGT 23526
Query: 530 PAELCVVLNDEKVEGVWLKD----GKEIT-------DLPGMQIVKQGAVHKLI--FPSMG 576
P + V N+ ++ W K G IT DLP + +K + + F G
Sbjct: 23527 PEPIMVKRNEITLQ--WTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSG 23584
Query: 577 PEHEGKYTFR----------AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAH 626
+ +Y FR +K ++S + D + ++ I V G T
Sbjct: 23585 LTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFR 23644
Query: 627 IKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDH 686
++ GKPLP + W + E+ E R ++ + +ALL + + +R D G +L+ N
Sbjct: 23645 LEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA 23704
Query: 687 GSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKK 746
GS + +++ VLDRP PP+G V+ ++ + W P +GG ++ ++VE+R +
Sbjct: 23705 GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRL 23764
Query: 747 SWIKIGEVDGKVTN-FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFA 805
+W + VTN K+ EG Y FRI+AVN GV +PLE+ V NP PG
Sbjct: 23765 AWTVVASE--VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPP 23822
Query: 806 SQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDG 865
+VT++ K+++T+ WN P DGG+ ++GYIVE+R + W+ NK I + V G
Sbjct: 23823 KSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTG 23882
Query: 866 LLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWRE 925
L ED EYEFRV A N AG G+PS + A DPV PG + H+ D++ +SI+LAW +
Sbjct: 23883 LTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGK 23942
Query: 926 PA--EGDPPSGYILEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAG 982
P G GY++E+ D +EW T + + T + + L E Q+Y R+ A+N+ G
Sbjct: 23943 PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVG 24002
Query: 983 VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG 1042
+GE + V+ AP+ DL + L+ +VVRAG + IH F G P P++ W ++
Sbjct: 24003 LGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREE 24062
Query: 1043 VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNL 1102
+ I K N++Q I++ R+D+G Y + L+N G + V+V D P PP NL
Sbjct: 24063 GEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNL 24122
Query: 1103 RLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLL 1160
+ E ++ L W P + + G +Y+I KR+++ + + + + V L
Sbjct: 24123 AVKEVRKDSAFLVW--EPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLT 24180
Query: 1161 PGRKYYFRVVARNEIGDSEPLDSRD 1185
G YYFRV+A NE G P+++ D
Sbjct: 24181 EGAIYYFRVMAENEFGVGVPVETVD 24205
Score = 352 bits (902), Expect = 2e-96
Identities = 208/628 (33%), Positives = 317/628 (50%), Gaps = 22/628 (3%)
Query: 580 EGK-YTFRA-------KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPF 631
EGK YTFR +GT SE +V D L+ L K +K+P
Sbjct: 19947 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 20006
Query: 632 RGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATA 691
+GKP P V+W K + + RVS+E L + +C + D+G + LKN G+
Sbjct: 20007 KGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEG 20066
Query: 692 TLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKI 751
T+ + V+ +P P G ++F E++ + +KW PKD+GG +T +I+E+R W+
Sbjct: 20067 TISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTC 20126
Query: 752 GEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVT 811
K T F ++ EG Y FR+ A N GV + L++E + A +P + P P +
Sbjct: 20127 ASAVQKTT-FRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIV 20185
Query: 812 DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTE 871
DV ++V++TW P + GG+P+ GY +E +++ S LW NK PI+ V GL E E
Sbjct: 20186 DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLE 20245
Query: 872 YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EG 929
YEFRV+A+N AG G+PS+PS VVA DP+ PPG + +++ + +S++L W EP G
Sbjct: 20246 YEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINI---TRNSVTLIWTEPKYDGG 20302
Query: 930 DPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVE 988
+GYI+E R +K W K + + +TV L+E KY FRIRA N AG + P E
Sbjct: 20303 HKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSE 20362
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHA-AFSGSPPPDVIWQKDGVPTKG 1047
+ + AP L +K + ++AG + ++A + G P P W K G +
Sbjct: 20363 STETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRP 20422
Query: 1048 RE--TITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLF 1105
+ IT + S I R D+G Y I N FG + V V D P PP + +
Sbjct: 20423 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEIS 20482
Query: 1106 EEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGR 1163
TLTW +P +++ G YI+ KR+ S W +E + S ++ T L+ G
Sbjct: 20483 NVSAEKATLTW--TPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGN 20540
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINK 1191
+Y FRV A N G EP+ S ++++
Sbjct: 20541 EYIFRVSAVNHYGKGEPVQSEPVKMVDR 20568
Score = 352 bits (902), Expect = 2e-96
Identities = 217/667 (32%), Positives = 334/667 (50%), Gaps = 19/667 (2%)
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAV--HKLIFPSMGPEHEGKYTF 585
GS +V E EG W+K T++ G V H+ F + G ++
Sbjct: 22467 GSKITGYIVEKKELPEGRWMK--ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSE 22524
Query: 586 RAKGTESEASVFIADPPTI--DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYK 643
++ T + + DPP I DP + + HA G + + GKP+P + W K
Sbjct: 22525 PSESTGAITARDEVDPPRISMDPKYKDTIVVHA-----GESFKVDADIYGKPIPTIQWIK 22579
Query: 644 DGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKP 703
E++ R+ ++ + L++ + VR DSG +LK KN G + T+++ VLDRP P
Sbjct: 22580 GDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP 22639
Query: 704 PQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFST 763
P+G V ++ + WK P +GG + +IVERR + W + + + + +
Sbjct: 22640 PEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV-DANVQTLSCKV 22698
Query: 764 NKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWN 823
K+ EG Y FRI+AVN GV +PLE+E V A NP P P+VT VTK+++ + W
Sbjct: 22699 TKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWE 22758
Query: 824 APTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAG 883
P DGG+ +LGY++E+R K W +K I + V GL+E+ +YEFRV A N AG
Sbjct: 22759 RPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAG 22818
Query: 884 PGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRA 941
+PS PS+ A DP+ PG + V D + SS+ L+W +P G GYI+E
Sbjct: 22819 LSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCD 22878
Query: 942 EDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPA 1000
EW+ CT I+ T V L+E+ +Y FRI A+N+AGVGE ++ +
Sbjct: 22879 VSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLE 22938
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
AP DL L+ + +RAG +L + G P P+V W K + I + + +
Sbjct: 22939 APDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSL 22998
Query: 1061 LINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
++++ R DSG Y + L+N G + VRV D P PP NL++ E ++V++TW P
Sbjct: 22999 VLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW--EP 23056
Query: 1121 DVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+ + G +YI+ KR+A+ ++ N + + L G YYFRV A NE G
Sbjct: 23057 PLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG 23116
Query: 1179 EPLDSRD 1185
P + D
Sbjct: 23117 LPAQTAD 23123
Score = 351 bits (901), Expect = 2e-96
Identities = 205/589 (34%), Positives = 309/589 (52%), Gaps = 19/589 (3%)
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKD--GMEVTEEERVSMERGEDQALL 665
VL+ + +TVK G T ++ RGKP P+V W KD ++T RV ++ D +
Sbjct: 18202 VLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKF 18261
Query: 666 TISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAP 725
+++ R D G ++ N GS A ++VLD+P P + ++ +++S + W P
Sbjct: 18262 SLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRN-LKIVDVSSDRCTVCWDPP 18320
Query: 726 KDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVS 785
+D+GG + +I+E+ + W + ++ EG Y FR+ A N G
Sbjct: 18321 EDDGGCEIQNYILEKCETKRMVWSTYSATV-LTPGTTVTRLIEGNEYIFRVRAENKIGTG 18379
Query: 786 DPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGS 845
P E++ V A + PG P+VT V+KE +T+ WN P DGG + GY +E+++K S
Sbjct: 18380 PPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 18439
Query: 846 NLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL 905
WVPVNK I + V LL D EY+FRV A N+ G G+PS+PS VVAKDP++PPG
Sbjct: 18440 TRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGP 18499
Query: 906 VQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMR-----AEDTKEWSKC-TKIPISG 957
+ V D++ SI+L W +P G P GY++EMR A + W +C +
Sbjct: 18500 PTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVR 18559
Query: 958 TCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVR 1017
+TV L E Q+Y FR+ A N+ G+G P EL + ++ P+ DL A ++ ++VR
Sbjct: 18560 KEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVR 18619
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLI--NSTKRSDSGVYRI 1075
AG + + A G P P V W+K G+ R+ + FL+ NST R DSG Y +
Sbjct: 18620 AGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNST-RDDSGKYSL 18678
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIM 1133
L N GE ++VRV D P P ++L++ + + ++W +P + G HYI+
Sbjct: 18679 TLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSW--APPENDGGSQVTHYIVE 18736
Query: 1134 KRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
KR+A TW T V + VT L+PG +YYFRV A NE G P D
Sbjct: 18737 KREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTD 18785
Score = 348 bits (892), Expect = 3e-95
Identities = 218/651 (33%), Positives = 325/651 (49%), Gaps = 40/651 (6%)
Query: 581 GKYTFRAKGTES------EASVFIAD------PPTIDPSVLEALAAHAITVKVGHTAHIK 628
G+Y FR K + A+V D PP+ID + V+ G +I
Sbjct: 16085 GEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSID-------LKEFMEVEEGTNVNIV 16137
Query: 629 VPFRGKPLPKVTWYK------DGME-VTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
+G P P +TW+K D E V + V+ +D L I R D+GL +
Sbjct: 16138 AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTIT 16197
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
N+ G+A+ + L+VL RP PP G ++F +S + + W PKD+GG +T +++E+R
Sbjct: 16198 AVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKR 16257
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
+K+W+ + + K ++ K+ EG Y FRI+A N G+ +PL++E A N
Sbjct: 16258 EANRKTWVHVSS-EPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSV 16316
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQ---- 857
PG +P V+ VT+ ++T+ W P DGG+PV GY +E + S W VN+DPI+
Sbjct: 16317 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 16376
Query: 858 GTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNS 917
G V GL+E ++Y+FRV A+N AG G S+PS A+DP+ PPG V+D + S
Sbjct: 16377 GVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKS 16435
Query: 918 SISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRI 975
S L W P + G +GYI+E + E +EW K + GT V GL E Y FR+
Sbjct: 16436 SADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRV 16495
Query: 976 RAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD 1035
RAVN AG+GEP E+ + +P L A ++ +VV AG + I A SG PPP
Sbjct: 16496 RAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPT 16555
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADF 1095
V W + TI + S +I + +RS GVY +L +NE GE + I V V D
Sbjct: 16556 VTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDV 16615
Query: 1096 PRPPTNLRLFEEVPN-TVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKY 1154
P P L + N + LTW D +Y+I KR++ W V
Sbjct: 16616 PGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA 16675
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINK-----DQIQDLSAK 1200
TV GL+ G+ Y+FR+ A N IG +++ + +I + ++ +DL K
Sbjct: 16676 TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVK 16726
Score = 348 bits (892), Expect = 3e-95
Identities = 210/595 (35%), Positives = 309/595 (51%), Gaps = 17/595 (2%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
IA TI PS+ L + +++ G I++P G+P P ++W KDG + + RV++E
Sbjct: 24304 IAKDLTIQPSL--KLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE 24361
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSC 717
+L I ++D G + N G+AT L + VL++P PP G V F E+S
Sbjct: 24362 ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADF 24421
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
V + W+ P GG ++ +IVE+R +W + + T K++ G YQFRI
Sbjct: 24422 VVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT-IKITKLKTGTEYQFRIF 24480
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYI 837
A N G S PL+++ V P + PG P VT ++K+ + + W+ P DGG ++GY
Sbjct: 24481 AENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYH 24540
Query: 838 VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAK 897
+E+++K S LWV +NK PIQ TK GL E EYEF+V A N G G+PS S VA+
Sbjct: 24541 LEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVAR 24600
Query: 898 DPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPI 955
DP PPG + + + + ++++L W++PA G +GYI+E + W K + +
Sbjct: 24601 DPCDPPGRPEAIVI---TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 24657
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
T +TV GL+E Q+Y FR+ A N AG EP + + A AP L + K +
Sbjct: 24658 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVI 24717
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSG 1071
VV AG + A G P PDV+W KDG T R I + + ++ R+D G
Sbjct: 24718 VVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGG 24777
Query: 1072 VYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGE--A 1128
Y + L N G I V+V D P PP L++ L WN P +Q+ G +
Sbjct: 24778 QYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN--PPLQDGGANIS 24835
Query: 1129 HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
HYII KR+ S +W + V + Y VT LLPG +Y FRV+A N+ G EPL+S
Sbjct: 24836 HYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLES 24890
Score = 345 bits (885), Expect = 2e-94
Identities = 290/986 (29%), Positives = 433/986 (43%), Gaps = 117/986 (11%)
Query: 268 WIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEP 327
WIK T ++ + Q KY IS +N DAG VG+ + ++ +++
Sbjct: 20719 WIKDTTGTALRITQFVVPDLQTKEKYNFRISAIN--DAG-----VGEPAVIPDVEIVER- 20770
Query: 328 LKFLGEMKP---VKVTERQTAVFEIRLS---------KKEPNFVWKFNGKELKRDDKYEI 375
EM P + R+T V LS + P W + LK E
Sbjct: 20771 -----EMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIEN 20825
Query: 376 TVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSR 435
T S L I + D+G+F +TI+ P S NVRV +
Sbjct: 20826 TESFT----LLIIPECNRYDTGKFV-----------MTIEN-PAGKKSGFVNVRVLDTPG 20869
Query: 436 ACLEC---ELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRA--------------ELIIE 478
L ++T VTL W D L+ G++ + KR + +
Sbjct: 20870 PVLNLRPTDITKDSVTLHW--DLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 20927
Query: 479 DAQLSDGGEYTVVAMQD-----GDPTEYYSTAIVTVEERLATVKS-GMSDVHAAT----- 527
LS+G EY M + G+PTE +T V E + S + D+ +T
Sbjct: 20928 VTGLSEGCEYFFRVMAENEYGIGEPTE--TTEPVKASEAPSPPDSLNIMDITKSTVSLAW 20985
Query: 528 -------GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHE 580
GS V+ K W IT + G++ V + G E
Sbjct: 20986 PKPKHDGGSKITGYVIEAQRKGSDQWT----HITTVKGLECVVRNLTE-------GEE-- 21032
Query: 581 GKYTFRAKGTES-------EASVFIADPPTIDPSV-LEALAAHAITVKVGHTAHIKVPFR 632
YTF+ S E+ I T+ P + L + + K G +++P
Sbjct: 21033 --YTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVL 21090
Query: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
G+P P VTW K + + +RV+ E +L I+ CVR DSG L +N G
Sbjct: 21091 GRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDV 21150
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
+ + V D P PP G ++F E+S V W P+++GG P++ ++VE R +W+++
Sbjct: 21151 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELA 21210
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTD 812
+ T + ++ G YQFR+ A N GV + + + A P + PG PQVT
Sbjct: 21211 TTVIRTT-YKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 21269
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
VTK+++TI+W+ P DGG+P+LGY VER+++ LW V+K + G GL + Y
Sbjct: 21270 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAY 21329
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGD 930
EFRVIA N AG +PS PS ++A DP+ PPG L++ + +++L W +P G
Sbjct: 21330 EFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNI---TRHTVTLKWAKPEYTGGF 21386
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVEL 989
+ YI+E R W K I +TV GL E Y FR+ A N AG + P E
Sbjct: 21387 KITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEP 21446
Query: 990 DKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE 1049
+ APK + + K ++++AG A + A SG PPP + W KDG +G
Sbjct: 21447 SDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTA 21506
Query: 1050 TI-TKSKNHSQFLIN-STKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFE 1106
+ K + S L+N + R DSG Y + N G A++ +V+V D P PP L + E
Sbjct: 21507 KLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTE 21566
Query: 1107 EVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRK 1164
L+W P + + G HYI+ KR+ S W A V K VT LL G +
Sbjct: 21567 VTSEKCVLSW--FPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNE 21624
Query: 1165 YYFRVVARNEIGDSEPLDSRDTWLIN 1190
Y FRV+A N+ G EPL+S +N
Sbjct: 21625 YIFRVMAVNKYGVGEPLESEPVLAVN 21650
Score = 341 bits (874), Expect = 3e-93
Identities = 190/575 (33%), Positives = 298/575 (51%), Gaps = 8/575 (1%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ +K G ++ G+P P + W KDG E+ ++ ++ + L + R DSG
Sbjct: 21471 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 21530
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
L N G A ++ VLDRP PP+G + E++ + W P D+GG + +
Sbjct: 21531 AYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY 21590
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
IV++R + +W + + +VT K+ +G Y FR++AVN GV +PLE+E V A
Sbjct: 21591 IVQKRETSRLAWTNVAS-EVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAV 21649
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
NP PP P+VT +TK+++ + W P DGG+ ++ YIVERR K W+ NK +
Sbjct: 21650 NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTL 21709
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ V GL E EYEFR++A N AG PS S A D V PG + V D+S
Sbjct: 21710 TDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSR 21769
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFF 973
SSIS+AW +P G +GY++E+ + EW T + T YT+ GL E Q+Y
Sbjct: 21770 SSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKI 21829
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
RI A+N G+GEP + +A P+ +L A L+ + +RA L + G P
Sbjct: 21830 RIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPA 21889
Query: 1034 PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVA 1093
P+V W +D + + +I + +++ ++ + R DSG Y + ++N G ++VRV
Sbjct: 21890 PEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVL 21949
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFS 1151
D P PP +L++ E +VTLTW+ P + + G +YI+ KR+++ + T A
Sbjct: 21950 DTPGPPQDLKVKEVTKTSVTLTWD--PPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHK 22007
Query: 1152 NKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDT 1186
+ V L G YYFRV+A NE G P ++ ++
Sbjct: 22008 TSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAES 22042
Score = 340 bits (872), Expect = 5e-93
Identities = 197/589 (33%), Positives = 296/589 (50%), Gaps = 11/589 (1%)
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
PP+++ L+ + VK G T RG P+P W DG E+ +E ++E
Sbjct: 17507 PPSVE---LDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 17563
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHM 720
++LTI NC+R D+G + + N GS T +HL+VLD P PP G + L+++ + +
Sbjct: 17564 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 17623
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W+ PKD+GG PV +IVE++ K +W + K T +++G Y FR+ A N
Sbjct: 17624 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-TKLKIPHLQKGCEYVFRVRAEN 17682
Query: 781 SEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVER 840
GV PL++ A + PP +P VTD+T+ A T++W P DGG+P+ GY +ER
Sbjct: 17683 KIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMER 17742
Query: 841 RKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPV 900
R+ + WV VNK PI K V GL E YEFRV A N AG +PS S + A P+
Sbjct: 17743 REV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPI 17801
Query: 901 KPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGT 958
KPPG + + D S + L W +P G P GY++E + T +W++ K +
Sbjct: 17802 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 17861
Query: 959 C-YTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVR 1017
C + V GLIE +Y FRI+A N G GEP EL + V A P+ +L + + VR
Sbjct: 17862 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVR 17921
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
G + I A G P PD+ W K+G + + R + + + I R+D G Y I
Sbjct: 17922 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYII 17981
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
+N G A+ V V D P P NL++ T++W + D ++I+ R
Sbjct: 17982 SAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR 18041
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ W A V + + LL +YYFRV A N++G ++++
Sbjct: 18042 KPNQKGWSIVASDV-TKRLIKANLLANNEYYFRVCAENKVGVGPTIETK 18089
Score = 335 bits (859), Expect = 2e-91
Identities = 196/574 (34%), Positives = 306/574 (53%), Gaps = 14/574 (2%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE--DQALLTISNCVRED 674
+ +K G + IK +G+P+P+VTW+KDG+E+ E+R++ME + L + + R+
Sbjct: 27968 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEI--EKRMNMEITDVLGSTSLFVRDATRDH 28025
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
G+ ++ KN GSA A + + V D P G + F ++G + + W AP ++G P+T
Sbjct: 28026 RGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPIT 28085
Query: 735 QFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF 794
+I+E+R + +W I E + +++ K+ G YQFR+ AVN GV PL+++ V
Sbjct: 28086 HYIIEKRETSRLAWALI-EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVV 28144
Query: 795 AGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPV-NK 853
A P P+ +++T ++T+TW P DGG+ + YI+ERR+K S WV V +K
Sbjct: 28145 AQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISK 28204
Query: 854 DPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSD 913
PI T+ V GL E EYEF V+A N AG G S S + ++PV PPG + V+D
Sbjct: 28205 RPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTD 28264
Query: 914 SSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKY 971
+S +++SL W +P G GYI+EM D +W K T YTV L ++Y
Sbjct: 28265 TSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEY 28324
Query: 972 FFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGS 1031
FR+ A+N AG G+ E+ ++A+ AP+ D+ A K VVRAG ++ + A+ G
Sbjct: 28325 KFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGR 28384
Query: 1032 PPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091
P P +W K R I + + S + + R+D+G Y + ++N G V+
Sbjct: 28385 PTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVK 28444
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA---HYIIMKRDASTATWYTAAER 1148
V D P PP + + + TL W+ +P + DG A HY++ KR+AS +W +E+
Sbjct: 28445 VLDTPGPPGPITFKDVTRGSATLMWD-APLL--DGGARIHHYVVEKREASRRSWQVISEK 28501
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
+ V L G YYFRV A NE G EP +
Sbjct: 28502 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYE 28535
Score = 331 bits (849), Expect = 2e-90
Identities = 210/619 (33%), Positives = 310/619 (50%), Gaps = 26/619 (4%)
Query: 582 KYTFRAKGTESEASVFIADPPTIDPSVLEA---------LAAHAITVKVGHTAHIKVPFR 632
+Y+FR + I+DP + V+ L + TV G + VPF
Sbjct: 22116 EYSFRVSAQNEKG---ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFI 22172
Query: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
G+P P VTW+KD + + + RV+ E E+ +LLTI + RED G ++KL N G A T
Sbjct: 22173 GRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIET 22232
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
L++ VLD+P PP G V+ E++ + + W PK +GG + +IVE+R +W +
Sbjct: 22233 LNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 22292
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTD 812
+ T +++ G YQFRI A N G S L +E A P + PG P VT
Sbjct: 22293 ATVARTT-IKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTL 22351
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
+++++ + WN P DGG+ V+GY +ER+++ S LWV +NK PI TK GL E EY
Sbjct: 22352 SSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEY 22411
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGD 930
EFRV A N G G+PS S VA+DP PPG + + V + +S++L W++P G
Sbjct: 22412 EFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIV---TRNSVTLQWKKPTYDGGS 22468
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV-GEPVEL 989
+GYI+E + W K + I T + V GL+E +Y FR+ A N AGV EP E
Sbjct: 22469 KITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSES 22528
Query: 990 DKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK--DGVPTKG 1047
+ A P+ + + K +VV AG + + A G P P + W K +
Sbjct: 22529 TGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTA 22588
Query: 1048 RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEE 1107
R I + + + R DSG Y + +N GE ++V+V D P PP +
Sbjct: 22589 RLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 22648
Query: 1108 V-PNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRK 1164
V TL W P +Q+ G +YI+ +R+ S W V + VT LL G +
Sbjct: 22649 VTAEKCTLAW--KPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNE 22706
Query: 1165 YYFRVVARNEIGDSEPLDS 1183
Y FR++A N+ G EPL+S
Sbjct: 22707 YTFRIMAVNKYGVGEPLES 22725
Score = 331 bits (848), Expect = 3e-90
Identities = 261/933 (27%), Positives = 421/933 (45%), Gaps = 67/933 (7%)
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEI 349
G +Y+ + +VN A S S D +++ E +EPL + + + A F +
Sbjct: 26150 GAEYVFRVKSVNKVGASDPSDS-SDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTM 26206
Query: 350 RL---SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+ + PN +W +L+ + T S LT I++A +DSG+++ N+
Sbjct: 26207 TVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLT----IENANRNDSGKYTLTIQNV 26262
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRW---KKDGQLLMHGTK 463
+ A LT+ + N+ V++ +T + L W + DG +
Sbjct: 26263 LSAASLTLVVKVLDTPGPPTNITVQD---------VTKESAVLSWDVPENDGGAPVKNYH 26313
Query: 464 YSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERL---ATVKSGM 520
K+A + + + + Y V +Q+G YY E + A K G+
Sbjct: 26314 IEKREASKKAWVSVTNN--CNRLSYKVTNLQEG--AIYYFRVSGENEFGVGIPAETKEGV 26369
Query: 521 SDVHAATGSPAELCVV-LNDEKVEGVWLK---DGK--------EITDLPGMQIVKQGAVH 568
+ P +L V ++ + V WLK DG E + VK
Sbjct: 26370 K-ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAK 26428
Query: 569 KLIFPSMGPEHEGKYTFRA-----KGTESEASVFIA-------DPPTIDPSVLEALAAHA 616
G +Y FR G + + +PP ID ++ +H
Sbjct: 26429 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID---MKNFPSHT 26485
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ V+ G + +P GKPLPKVT +DG+ + R + E + + + V D+G
Sbjct: 26486 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 26545
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
+ N G+ A +++ VLDRP PP G V +++ V +KW+ PK +GG VT +
Sbjct: 26546 RYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNY 26605
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
I+ +R W ++ + T K+ G+ YQFRI A N G+SD +++ V
Sbjct: 26606 ILLKRETSTAVWTEVSATVAR-TMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVK 26664
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
P PG S P VT+VT+E++T+ W+ P +GG+ V+GY +E + + S LW NK I
Sbjct: 26665 LPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI 26724
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ T V + YEFRV A N AG G+PS PS V+A D +PP +++ ++D S
Sbjct: 26725 RTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPP---RNVRITDISK 26781
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+S+SL+W++PA G +GYI+E R W+K + ++ T + + GL + +Y FR
Sbjct: 26782 NSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFR 26841
Query: 975 IRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
+ A N G + P E+ + + P DL + RAGT++ + A SG P
Sbjct: 26842 VFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPA 26901
Query: 1034 PDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091
P + W KD + T + + + + LI R +SG Y + L+N G A I V+
Sbjct: 26902 PTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQ 26961
Query: 1092 VADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF 1150
+ D P PP F+ V +TL W D HYI+ KR+ S W +E +
Sbjct: 26962 ILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLE 27021
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
T T ++ G +Y FRV A N+ G EPL+S
Sbjct: 27022 ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 27054
Score = 330 bits (846), Expect = 6e-90
Identities = 206/622 (33%), Positives = 309/622 (49%), Gaps = 19/622 (3%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
+K+G ++ ++ +GK +F K + + PPT+ + L T++V
Sbjct: 16781 LKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELA---PPTLHLDFRDKL-----TIRV 16832
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
G + + GKP PKV+W+KD +V E++R ++ L R DSG +
Sbjct: 16833 GEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVV 16892
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
++N GS ++V+DRP PP G V F E++ + + WK P D+GG +T +I+E++
Sbjct: 16893 VENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKK 16952
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
VGK W+ + K T +K+ EGK Y FRI A N G+SDPL ++ + A +
Sbjct: 16953 EVGKDVWMPVTSASAKTT-CKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRV 17011
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG-TK 860
P QP VT+VTK++ +TWN P DGG P+ YI+E+R+ S W V KDPI TK
Sbjct: 17012 PDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTK 17070
Query: 861 CTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSIS 920
V LLE +YEFRV A N+ G G PS PS V AKDP+ P + D++ +S+
Sbjct: 17071 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 17130
Query: 921 LAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPIS--GTCYTVGGLIERQKYFFRIR 976
L W+ P G GYI+E + +EW + P S T Y V GL + Q Y FR+
Sbjct: 17131 LTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVL 17190
Query: 977 AVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
AVN AG +P + + V P+ L A + ++ G L + A G P P V
Sbjct: 17191 AVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKV 17250
Query: 1037 IWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVAD 1094
W+K+ PTK R +T S+ I + D G+Y + ++N G + V V D
Sbjct: 17251 TWKKEDRDAPTKARIDVTPV--GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD 17308
Query: 1095 FPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKY 1154
P PP +L + E ++ LTW D +Y++ +RD ++A W + +
Sbjct: 17309 KPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSH 17368
Query: 1155 TVTGLLPGRKYYFRVVARNEIG 1176
L G +Y FRV A N+ G
Sbjct: 17369 FAKHLNEGNQYLFRVAAENQYG 17390
Score = 326 bits (836), Expect = 8e-89
Identities = 262/890 (29%), Positives = 401/890 (45%), Gaps = 86/890 (9%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQ 411
P VW EL DK + + G L IKDA D G + A G+ A+
Sbjct: 15134 PTKVWTKEEGEL---DKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAAR 15190
Query: 412 LTIDRIPIKFVSNLKNVRVKERSRACLECELTSKD----VT--LRWKKDGQLLMHGTKYS 465
+ + +P V +LK V V R L D +T + +KD + MH +
Sbjct: 15191 VEVFDVPGP-VLDLKPV-VTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQP 15246
Query: 466 MNHEGKRAELIIEDAQLSDGGEYT--VVAMQD---GDPTEYYSTAIV------TVEERLA 514
+ E + ++ L +G EY V+A G P E V T ERL
Sbjct: 15247 IETERSKCDI----TGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLT 15302
Query: 515 TVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPS 574
+ S + P ++G ++ K D P + V + F
Sbjct: 15303 YTERTKSTITLDWKEPRSN----GGSPIQGYIIE--KRRHDKPDFERVNKRLCPTTSFLV 15356
Query: 575 MGPEHEGKYTFRAKGT----ESEAS----VFIAD---PPTIDPSVLEALAAHAITVKVGH 623
+ Y FR K ESE S V I D PPTI + ++ I VK G
Sbjct: 15357 ENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRL--SVRGDTIKVKAGE 15414
Query: 624 TAHIKVPFRGKPLPKVTWYK---------DGMEVTEEERVSMERGEDQALLTISNCVRED 674
HI G P+PK+ W K D +++T+EE + R E + L+I VRED
Sbjct: 15415 PVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEE---VSRSEAKTELSIPKAVRED 15471
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
G + N GS +H+ V DRP PP+ + ++ ++ W AP DNGG +T
Sbjct: 15472 KGTYTVTASNRLGSVFRNVHVEVYDRPSPPRN-LAVTDIKAESCYLTWDAPLDNGGSEIT 15530
Query: 735 QFIVERRAVGKKS--WIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE 792
+++++R +K W ++ + + K+ Y+FR+ AVN G+SD ++++
Sbjct: 15531 HYVIDKRDASRKKAEWEEVTNTAVE-KRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDK 15589
Query: 793 VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW---- 848
V +P PG +P+V TK ++ ++W P +GG+P+ GY +E+R++GS W
Sbjct: 15590 VVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVS 15649
Query: 849 -VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
P+ K ++G + V LLE +Y+FR +A+N AG G PS PS VA DP+ PPG
Sbjct: 15650 RAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPS 15709
Query: 908 DLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTK-IPISGTC-YTVG 963
V D + SSISL W+ PA+ G P GYI+EM+ E T +W + + + TC V
Sbjct: 15710 CPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVP 15769
Query: 964 GLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC 1023
L E +KY FR++AVNEAG EP + + A P+ + + +V +AG+ +
Sbjct: 15770 NLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIR 15829
Query: 1024 IHAAFSGSPPPDVIWQKDGVPTKGRE----------TITKSKNHSQFLINSTKRSDSGVY 1073
I A G P P W+ DG K + + ++N S +I KRS +G Y
Sbjct: 15830 IPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKY 15889
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM 1133
I +N+ G+ + V+V D P PP +L++ + + L+W D D Y+I
Sbjct: 15890 SITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIE 15949
Query: 1134 KRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
KR W S + V LL ++Y+FRV A N G P+++
Sbjct: 15950 KRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVET 15999
Score = 326 bits (836), Expect = 8e-89
Identities = 217/659 (32%), Positives = 323/659 (49%), Gaps = 43/659 (6%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGT---------ESEASVFIADPPTIDPSVLEAL 612
V+ G +L F + +Y FR K E+ +SV I +P + L +
Sbjct: 28593 VEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGI 28652
Query: 613 AAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVR 672
IT K G I VP G+P PKVTW + M + E +RVS+ +D+ LT+ + +R
Sbjct: 28653 TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMR 28712
Query: 673 EDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRP 732
DSG L L+N G T ++ + V+ RP P G +E +S + W PKD GG
Sbjct: 28713 GDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTE 28772
Query: 733 VTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE 792
+T +IVE+R G +W + K T + + Y FR+ + N GVS PLE+
Sbjct: 28773 ITNYIVEKRESGTTAWQLVNS-SVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAP 28831
Query: 793 VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN 852
+ A +P PP ++P+V V+ A++I W P DGG+ ++GY VE++++ + LWV N
Sbjct: 28832 IIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKEN 28891
Query: 853 KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVS 912
K P V GL+E EY+FR A+N AG + S S ++A++PV PG + V+
Sbjct: 28892 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE---VT 28948
Query: 913 DSSNSSISLAWREPA--EGDPPSGYILEMRAED---TKEWSKCTKIPISGTCYTVGGLIE 967
D + S++SL W PA G GYI+E + W KC +S +TV L E
Sbjct: 28949 DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE 29008
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP------AAPKFDLSARLKSHMV-VRAGT 1020
Y FR+ A N AGV + KG + P A PK +L ARL +V +RAG+
Sbjct: 29009 GDTYEFRVLAKNAAGV-----ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGS 29063
Query: 1021 ALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
L + AA G P P +IW K + + ++ + + +I RSDSG Y + ++
Sbjct: 29064 DLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK 29123
Query: 1079 NEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA---HYIIMKR 1135
N G + V+V D P P L + TL W+ QEDG A HYI+ +R
Sbjct: 29124 NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLP---QEDGGAEITHYIVERR 29180
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIG-----DSEPLDSRDTWLI 1189
+ S W + Y VT L+ +Y FRV A N+ G +SEP+ +R+++ I
Sbjct: 29181 ETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTI 29239
Score = 325 bits (833), Expect = 2e-88
Identities = 227/759 (29%), Positives = 365/759 (48%), Gaps = 54/759 (7%)
Query: 587 AKGTESEASVFIADPPTIDPSVLEA-LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+KG+ES V D + L+A L +T++ G + GKP PK+ W K
Sbjct: 29026 SKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGD 29085
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
E+ E+VS++ +A I C R DSG L +KN G+ ++ + VLD P P
Sbjct: 29086 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPC- 29144
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNK 765
G++ ++ + W P+++GG +T +IVERR + +W+ I E + ++ +
Sbjct: 29145 GKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWV-IVEGECPTLSYVVTR 29203
Query: 766 VEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
+ + Y FR+ AVN G P+E+E + A N P P+ KE + I W P
Sbjct: 29204 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 29263
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKD-PIQGTKCTVDGLLEDTEYEFRVIAVNKAGP 884
DGG + Y+V++R+K S W VNKD + T+ V L+E +Y+FRV AVN AG
Sbjct: 29264 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 29323
Query: 885 GQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAE 942
+PS S+ + ++P PG V D++ SISLAW +P G GY+LEM+ +
Sbjct: 29324 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 29383
Query: 943 DTKEWSKC-TKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAA 1001
DT +W + T I T +TV L QKY FR+ AVN G+ E E + +
Sbjct: 29384 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 29443
Query: 1002 PKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
P +L+ LK + +RAG +L + + SG PPP + W K G+ R I ++++S +
Sbjct: 29444 PDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI 29503
Query: 1062 INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
++ R D+G Y I +N+ G+ + V+V D P P ++++ E ++VT+TW P
Sbjct: 29504 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITW-EIPT 29562
Query: 1122 VQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+ DG A +YI+ KR+A+ + T + Y ++GL+ G YYFRV+ N G
Sbjct: 29563 I--DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 29620
Query: 1179 EPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLG 1238
EP ++ D L+++ PL P L D T + L
Sbjct: 29621 EPCETSDAVLVSE-------------------------VPLVP-AKLEVVDVTKSTVTLA 29654
Query: 1239 NPRPTVTLYKGDVNIT--------ANSKFWYNSTSGVCTLVIPTCTLKDSGD---YSVLV 1287
+P LY G +T A ++ W + T++ T T + G+ + +
Sbjct: 29655 WEKP---LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRA 29711
Query: 1288 ENELGKDRSSCTLTVYDKDDKSVVASI-TESLQKKSKHL 1325
+NE G T+T D V+ +I ++ +K+ H+
Sbjct: 29712 QNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHV 29750
Score = 325 bits (832), Expect = 2e-88
Identities = 195/607 (32%), Positives = 305/607 (50%), Gaps = 16/607 (2%)
Query: 592 SEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE 651
S A +A I+P V A ++++ V+VG I+VP G+P P +TW KDG+ + +
Sbjct: 23216 SLAVPIVAKDLVIEPDVKPAFSSYS--VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQT 23273
Query: 652 ERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFL 711
R+++ D L+I ++D G + + N G TA++ + LD+P PP+G V+F
Sbjct: 23274 TRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFD 23333
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKA 771
++S + + W P GG +T +IV++R W + + T K++ G
Sbjct: 23334 DVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT-LKVTKLKTGTE 23392
Query: 772 YQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA 831
YQFRI A N G S LE++ + A P + PG P T ++K+++ I W+ P +GG+
Sbjct: 23393 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 23452
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
PV+GY +ER+++ S LW VNK I T+ L E EYEFRV A N G G+ S S
Sbjct: 23453 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 23512
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSK 949
VA+DP PPG + + V + I+L W +P G +GYI+E R W K
Sbjct: 23513 ECYVARDPCDPPGTPEPIMV---KRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMK 23569
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSA 1008
+ + T +TV GL E Q+Y FR+ A N AG + +P + + A P+ +
Sbjct: 23570 ASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP 23629
Query: 1009 RLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTK 1066
+ + +VV AG + A G P P + W + + R I + + ++
Sbjct: 23630 KFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAI 23689
Query: 1067 RSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQED 1125
R D G Y + N G + ++V+V D P PP +++ +LTW SP +Q+
Sbjct: 23690 RIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW--SPPLQDG 23747
Query: 1126 GE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
G +HY++ KR+ S W A V +N VT LL G +Y FR++A N+ G EPL+S
Sbjct: 23748 GSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLES 23807
Query: 1184 RDTWLIN 1190
+ N
Sbjct: 23808 APVLMKN 23814
Score = 318 bits (816), Expect = 2e-86
Identities = 196/641 (30%), Positives = 304/641 (47%), Gaps = 25/641 (3%)
Query: 557 PGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEA--------SVFIADPPTIDPSV 608
P + + V L G + KY FR + V+ A + P +
Sbjct: 18843 PADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI 18902
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L IT+K G I+ GKP P W K EV +++ + + ++L I
Sbjct: 18903 L---MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 18959
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
+ R+DSG L +N G+ T + + V+D P PPQ + ++ + W P ++
Sbjct: 18960 DVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLED 19019
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG +T +IVE+ V + W+ K T+ K+ G+ Y FR+ A N G+S+PL
Sbjct: 19020 GGSNITNYIVEKCDVSRGDWVTALASVTK-TSCRVGKLIPGQEYIFRVRAENRFGISEPL 19078
Query: 789 ETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW 848
+ ++ A P P +VT V K+ + + W+ P DGG+P++GY++ER+++ S LW
Sbjct: 19079 TSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLW 19138
Query: 849 VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQD 908
V N ++ T+ GL+E EY FR+ A+NKAG PS P+ V A+ PV PPG +
Sbjct: 19139 VKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPE- 19197
Query: 909 LHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIP--ISGTCYTVGG 964
V D + S++SL W P G GY +E +W +C P I YT G
Sbjct: 19198 --VIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATG 19255
Query: 965 LIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCI 1024
L E+ +Y FR A + P E V + P+ DLS +KS + V+AGT +C+
Sbjct: 19256 LEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 19315
Query: 1025 HAAFSGSPPPDVIWQKDGVPTKGRETI--TKSKNHSQFLINSTKRSDSGVYRILLQNEFG 1082
A G P P V W+KDG K E I +N + S R DSG Y I +N G
Sbjct: 19316 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 19375
Query: 1083 EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTA 1140
I ++V D P PP ++++ + + L+W P +++ G +YI+ KR+ S
Sbjct: 19376 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSW--EPPLEDGGSEITNYIVDKRETSRP 19433
Query: 1141 TWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPL 1181
W + V +V L+ G +Y FR+ A N+ G +P+
Sbjct: 19434 NWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPV 19474
Score = 317 bits (812), Expect = 5e-86
Identities = 193/605 (31%), Positives = 291/605 (48%), Gaps = 26/605 (4%)
Query: 598 IADPPTIDPSVLEALA-----------AHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
++DP TI P ++ L +TV++GH H+++P++GKP P ++W KDG+
Sbjct: 27543 LSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGL 27602
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
+ E E V + E++ L+I N +E G + L N + + L P P+G
Sbjct: 27603 PLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKG 27662
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
+ F E+ V + W P+DNGG +T + +E+R + +W + + T N V
Sbjct: 27663 PIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLV 27722
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
++ + YQFR+ A N GVS PL + + A + PG +P + +VT + +++TW+AP
Sbjct: 27723 KDAE-YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPV 27781
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQ 886
DGG+ V G+ VE++++ S LW VN PI G + GL+E +Y+FRV A N AG
Sbjct: 27782 YDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSS 27841
Query: 887 PSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDT 944
PS PS +A PV PPG + D + +I+L W P G GY +E R +
Sbjct: 27842 PSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKR-QGN 27897
Query: 945 KEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG-VRAMPPPAAPK 1003
+ W +C +S YTV GL +Y FRI A N G P G + P
Sbjct: 27898 ERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPI 27957
Query: 1004 FDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRET--ITKSKNHSQFL 1061
+ +++++G +L I A G P P V W KDGV + R IT +
Sbjct: 27958 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 28017
Query: 1062 INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+ R GVY + +N G A+ +I V+V D P F + W +P
Sbjct: 28018 VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAP- 28076
Query: 1122 VQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
DG A HYII KR+ S W ++ + YT L+ G +Y FRV A N+ G
Sbjct: 28077 -LNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 28135
Query: 1179 EPLDS 1183
PLDS
Sbjct: 28136 RPLDS 28140
Score = 313 bits (801), Expect = 9e-85
Identities = 262/892 (29%), Positives = 399/892 (44%), Gaps = 90/892 (10%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTID 415
P W +GKE+K D+ +T+ D ++ L++ + +D+G ++ N + A +I+
Sbjct: 14416 PTVSWHKDGKEVKASDR--LTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 14473
Query: 416 RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAEL 475
I K+++ + +++ C+LT + DG + G+R +
Sbjct: 14474 VKVIGLPGPCKDIKASDITKS--SCKLTWEPPEF----DGGTPILHYVLERREAGRRTYI 14527
Query: 476 IIEDAQ---------LSDGGEY--TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524
+ + L GEY V A+ EY + + DV
Sbjct: 14528 PVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 14587
Query: 525 AATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVK---------QGAVHKLIFPSM 575
+ + + +G G +I +I K + V L + +
Sbjct: 14588 VHNPTAEAMTITWKPPLYDG-----GSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAK 14642
Query: 576 GPEHEGKYTFRAKGTESEASVFI---ADPPT--IDP-SVLEALAAHAITVKVGHTAHIKV 629
G E +Y FR + E+ A + A PPT +DP + + ++ VK G +
Sbjct: 14643 GLEEGKEYQFRVRA-ENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDA 14701
Query: 630 PFRGKPLPKVTWYKDGM--------------------EVTEEE--------RVSME---R 658
G P P +TW KD EV EEE R+S++ +
Sbjct: 14702 SISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKK 14761
Query: 659 GEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCV 718
GE Q L + + +R D GL ++K++NDHG A A +SVLD P PP V F ++ + V
Sbjct: 14762 GESQ--LRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFV-FEDIRKTSV 14818
Query: 719 HMKWKAPKDNGGRPVTQFIVERRAVGK--KSWIKIGEVDGKVTNFSTNKVEEGKAYQFRI 776
KW+ P D+GG + + +E++ K WI + + +S K+ EGK Y FR+
Sbjct: 14819 LCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTL-RHCKYSVTKLIEGKEYLFRV 14877
Query: 777 LAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGY 836
A N G P ++ + A +P PP +P V DVT ++ + WN P +D G+P+LGY
Sbjct: 14878 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEP-KDNGSPILGY 14936
Query: 837 IVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVA 896
+E+R+ S W VNK + K VDGLLE Y FRV A N AGPG+ S PS A
Sbjct: 14937 WLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTA 14996
Query: 897 KDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIP 954
DP+ PPG V+D+S+++I L W PA G GY ++ + T EWS+CT+
Sbjct: 14997 HDPISPPG-PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 15055
Query: 955 ISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
I YTV + E Y R+ AVN AG G P E + V P P +L +K +
Sbjct: 15056 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE-TQPVTVAEPQEPPAVELDVSVKGGI 15114
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
+ AG L I A +G P P +W K +G K R I S+ +I R D G Y
Sbjct: 15115 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 15174
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---Y 1130
I N G V V D P P +L+ L W+ D ++DG + +
Sbjct: 15175 VITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWS---DPEDDGGSEITGF 15231
Query: 1131 IIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
II ++DA TW E S K +TGLL G++Y FRV+A+N+ G P++
Sbjct: 15232 IIERKDAKMHTWRQPIETERS-KCDITGLLEGQEYKFRVIAKNKFGCGPPVE 15282
Score = 308 bits (790), Expect = 2e-83
Identities = 202/595 (33%), Positives = 288/595 (48%), Gaps = 19/595 (3%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
IA I PSV L H VK I VPF+G+P V W KDG + E RV++
Sbjct: 25387 IARDIEIKPSV--ELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVS 25444
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSC 717
+ L+I +ED G L + N GS T + + VLDRP PP G + E+S
Sbjct: 25445 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDS 25503
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
+ + W P+ +GG ++ +IVE++ +W + + + T+ ++ G YQFR+
Sbjct: 25504 ITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVAR-TSIKIVRLTTGSEYQFRVC 25562
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYI 837
A N G S E+ V A P PPG P+V TK + +TW P DGG+ V+GY
Sbjct: 25563 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 25622
Query: 838 VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAK 897
+E +++ S LW NK I T+ V GL E YE+RV A N AG G+ S V A+
Sbjct: 25623 LEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPAR 25682
Query: 898 DPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPPSGYILEMRAEDTKEWSKCTKIPI 955
DP PPG + V++ + S+SL W +P G +GYI+E R W KC I
Sbjct: 25683 DPCDPPGQPE---VTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNI 25739
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEA-GVGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
T + V L E Q+Y FR+ A N A V EP E + P+ + + + +
Sbjct: 25740 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVI 25799
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGV 1072
VV+AG L I+A +G P P + W KDG + + R I + NH+ + R D+G
Sbjct: 25800 VVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQ 25859
Query: 1073 YRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGEA--- 1128
Y + L+N G ++ +V D P PP L + +L+W QEDG A
Sbjct: 25860 YVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRP---QEDGGADID 25916
Query: 1129 HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+YI+ KR+ S W + VT LL G +Y FRV N+ G EPL+S
Sbjct: 25917 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLES 25971
Score = 293 bits (751), Expect = 6e-79
Identities = 187/608 (30%), Positives = 301/608 (49%), Gaps = 25/608 (4%)
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
++ TE +V + P I L+ +TVK G + GKP PK+TW K M
Sbjct: 13673 SRPTEEIQAVDTQEAPEI---FLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM 13729
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
+ +++R+++E ++ +TI + R D+G +++ N G ATA + ++VLD+P PP
Sbjct: 13730 ILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAA 13789
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
+ +++ + W P+D+GG +T ++VERRA + W K+ K TNF K+
Sbjct: 13790 -FDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTV-KDTNFKATKL 13847
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
K Y FR+ A N GV +P++ + A +PPG ++ + +D+TK+AVT+TW P
Sbjct: 13848 IPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPD 13907
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQ 886
DGG+P+ GY VER ++ WV NK P++ T V GL +Y FRV+A N AGPG+
Sbjct: 13908 DDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGK 13967
Query: 887 PSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDT 944
PS + ++ KDP+ PP V D +S+ L W +P G Y++EM T
Sbjct: 13968 PSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGT 14027
Query: 945 KEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV---RAMPPPAA 1001
EW + + + T + + GL+E Q+Y FR+RAVN+AG EP E V + PP+
Sbjct: 14028 DEWVRVAE-GVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSP 14086
Query: 1002 PKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
P++ + + A + GSP + I +K V KG +T+ + ++
Sbjct: 14087 PRWLEVINITKN---TADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 14143
Query: 1062 INSTKRSDSGVYRILLQNEFGEARY---DIHVRVAD---FPRPPTNLRLFEEVPNTVTLT 1115
+ V+R+ +N G++ Y + V D P PP L + + V L
Sbjct: 14144 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLK 14203
Query: 1116 WNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSN-KYTVTGLLPGRKYYFRVVAR 1172
W P + G Y+I K++ W A + + + VT ++ G + F+V A
Sbjct: 14204 W--EPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAE 14261
Query: 1173 NEIGDSEP 1180
NE G P
Sbjct: 14262 NEAGVGHP 14269
Score = 285 bits (729), Expect = 2e-76
Identities = 315/1307 (24%), Positives = 527/1307 (40%), Gaps = 123/1307 (9%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
EF+ KPQ + EG+KA F + + P + WKR+ ++ K + K+ VL +
Sbjct: 12553 EFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKT-LESGDKYDVIADGKKRVLVV 12610
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTV-----------SLLVTEGQEKM-------DFKKM 169
+ T D Y + A A TV V E QE + + K
Sbjct: 12611 KDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKA 12670
Query: 170 LKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKV 229
R A K + +K+++ L ++ T+ RG K V
Sbjct: 12671 KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVK-SAANLIV 12729
Query: 230 EVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPL----RIQYSLGKYD 285
E E +RI++PL+D ET +V F C ++ NV + W K E + R+ Y + KY
Sbjct: 12730 EEEDLRIVEPLKDIETMEKKSVTFWC--KVNRLNVTLKWTKNGEEVPFDNRVSYRVDKY- 12786
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
K+ML I + D G Y ++ G + AEL +++ P +F+ ++ VTE A
Sbjct: 12787 ------KHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDA 12840
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
VF +LS+++ N W NG+E+K KY+ +DG H L IKD RL D E++ +
Sbjct: 12841 VFSCQLSREKANVKWYRNGREIKEGKKYKF--EKDGSIHRLIIKDCRLDDECEYACGVED 12898
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
+A+L ++ IP++ + +++ + EL V ++W ++ +++ G K+
Sbjct: 12899 RKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQ 12958
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
M EGK L I D + D GEY +A +D + A +K+ D+
Sbjct: 12959 MMSEGKIHRLQICDIKPRDQGEYRFIA-KDKEARAKLELAAAP------KIKTADQDLVV 13011
Query: 526 ATGSPAELCVVLND-EKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
G P + V + K E W K+ + ++ + + +++ G + K
Sbjct: 13012 DVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT-IDTTAEQTSFRILEAKKGDKGRYKIV 13070
Query: 585 FRAKGTESEA----SVFIADPPTIDPSVLEAL-----AAHAITVKVGHTAHIKVPFRGKP 635
+ K ++E V P + V E A + G + I +
Sbjct: 13071 LQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRD 13130
Query: 636 LPKVTWY--KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
+ + TW D E E +++G + L +S R +G ++ D+ +
Sbjct: 13131 IKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE---PVETDNPVEARSK 13187
Query: 694 HLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGE 753
+ D P PP V +++ V + W+ P+ +GG +T +++E R W
Sbjct: 13188 Y----DVPGPPLN-VTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMT 13242
Query: 754 VDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP-LETEEVFAGNPIEPPGFASQPQVTD 812
V + + + V EG+ Y FR+ A N GV P T V +PIE P +D
Sbjct: 13243 VRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSD 13302
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
T+ +V + W P +DGG+P+LGYI+ER ++G + W+ N + V GL + +Y
Sbjct: 13303 QTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKY 13362
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPP 932
+RV A NKAG PS + A D P + DL + + + P P
Sbjct: 13363 LYRVSAENKAGVSDPSEILGPLTADDAFVEPTM--DL---SAFKDGLEVIVPNPITILVP 13417
Query: 933 S-GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDK 991
S GY T W K+ +G +R K + A E + DK
Sbjct: 13418 STGY-----PRPTATWCFGDKVLETG---------DRVK-MKTLSAYAELVISPSERSDK 13462
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAG----------TALCIHAAFS------GSPPPD 1035
G+ + K +S + +++ R T +H + GSP
Sbjct: 13463 GIYTLKLENRVK-TISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTG 13521
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGE---ARYDIHVRV 1092
+ +K V K + +F + + ++++ +N+ G A D V +
Sbjct: 13522 YVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNM 13581
Query: 1093 ---ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERV 1149
A P PP N++ + N++ LTW+ + YI+ + + W E V
Sbjct: 13582 STPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPV 13641
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
K VTGL G+ Y +RV A N G S+P SR T ++IQ + + P D
Sbjct: 13642 AETKMEVTGLEEGKWYAYRVKALNRQGASKP--SRPT-----EEIQAVDTQEAPEIFLD- 13693
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
V L TV G + G P P +T K D+ + + + + T
Sbjct: 13694 ------VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST 13747
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
+ I D+G Y + N G+ + + V DK IT+
Sbjct: 13748 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITD 13794
Score = 273 bits (699), Expect = 6e-73
Identities = 160/493 (32%), Positives = 252/493 (51%), Gaps = 15/493 (3%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ +E + ++ + +KW P+ +GG P+T +IVE+R V +K W + + K T
Sbjct: 14084 PSPPRW-LEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV-DTTVKDTK 14141
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVT 819
+ + EG Y FR+ A N+ G SD E E+ V A + PG V DVTK V
Sbjct: 14142 CTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVD 14201
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAV 879
+ W P DGG P+ Y++E++++ WV K V ++E TE +F+V A
Sbjct: 14202 LKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAE 14261
Query: 880 NKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYIL 937
N+AG G PS P+ + +DP PP DLHV+D+ I++AW+ P + G P GY +
Sbjct: 14262 NEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHV 14321
Query: 938 EMRAEDTKEWSKCTKIPISGTCYTV-GGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
EM T++W + PI + V G++ ++Y R+RAVN GV EP E+ + V A
Sbjct: 14322 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 14381
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKN 1056
P P DL ++V G L I F P P V W KDG K + +T +
Sbjct: 14382 DPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKND 14438
Query: 1057 H--SQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
H + + + R+D+G+Y I L+N+ G A I+V+V P P +++ + ++ L
Sbjct: 14439 HISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKL 14498
Query: 1115 TWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVAR 1172
TW P + G HY++ +R+A T+ +TV L+P +Y+FRV A
Sbjct: 14499 TW--EPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 14556
Query: 1173 NEIGDSEPLDSRD 1185
N++G E ++ ++
Sbjct: 14557 NKVGGGEYIELKN 14569
Score = 255 bits (652), Expect = 2e-67
Identities = 168/569 (29%), Positives = 270/569 (47%), Gaps = 36/569 (6%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
I V+ G + +P +GKP P W K+G ++++ R + E L I R DSG
Sbjct: 30146 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK--RAMIATSETHTELVIKEADRGDSG 30203
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
L L+N G + + V+ P P+G +E+ ++ V + W+ P D+GG + +
Sbjct: 30204 TYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGY 30263
Query: 737 IVERRAVGKKSWIKIGEVDGKV--TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF 794
I+ERR V K +W I D +V T+ ++E Y FR+ A N G+S PL++EE
Sbjct: 30264 ILERREVPKAAWYTI---DSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 30320
Query: 795 AG----NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP 850
NP EPP ++ P+V DVTK +V+++W+ P DGG+ V GY +ER++ ++ WV
Sbjct: 30321 TPKTPLNPPEPP--SNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 30378
Query: 851 VNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLH 910
NK I T TV GL+ D EY+FR+IA N G + S S VV KDP P +L
Sbjct: 30379 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 30438
Query: 911 VSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ S S++L W +P G GY +E R W K K I +T+GGL+E
Sbjct: 30439 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 30498
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRA-MPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
+Y FR+ A NE G+ P ++ + AP + +K + + G A +
Sbjct: 30499 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAP--GIRKEMKD-VTTKLGEAAQLSCQ 30555
Query: 1028 FSGSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEA 1084
G P PD+ W + G + ++ + + + H+ + + ++ D GVY + NE GE
Sbjct: 30556 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT-LTVMTEEQEDEGVYTCIATNEVGEV 30614
Query: 1085 RYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
+ + P+ L E+ V T H + + R TW+
Sbjct: 30615 ETSSKLLLQATPQFHPGYPLKEKYYGAVGSTL----------RLHVMYIGRPVPAMTWF- 30663
Query: 1145 AAERVFSNKYTVTGLLPGRKYYFRVVARN 1173
+++ N +T + ++Y +V +N
Sbjct: 30664 HGQKLLQNSENIT--IENTEHYTHLVMKN 30690
Score = 252 bits (643), Expect = 2e-66
Identities = 205/799 (25%), Positives = 359/799 (44%), Gaps = 50/799 (6%)
Query: 438 LECELTSKD-VTLRWKK---DG--QLLMHGTKYSMNHEG---KRAELIIEDAQLSDGG-- 486
LE SKD VTL+W+K DG ++L + +Y + + K + I+D Q + GG
Sbjct: 30437 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 30496
Query: 487 -----EYTVVAMQDGDPTEYYSTAIVTVEERLAT-----VKSGMSDVHAATGSPAEL-CV 535
E+ V A + + TA+ +++ +L + ++ M DV G A+L C
Sbjct: 30497 EATEYEFRVFAENETGLSRPRRTAM-SIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 30555
Query: 536 VLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKG----TE 591
++ + W + GKE+ ++ G H L + E EG YT A E
Sbjct: 30556 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 30615
Query: 592 SEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE 651
+ + + + P P + VG T + V + G+P+P +TW+ +
Sbjct: 30616 TSSKLLLQATPQFHPGYPLKEKYYGA---VGSTLRLHVMYIGRPVPAMTWFHGQKLLQNS 30672
Query: 652 ERVSMERGEDQALLTISNCVRED-SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEF 710
E +++E E L + N R+ +G ++L N G+ A L + + D+P P G +
Sbjct: 30673 ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVI 30732
Query: 711 LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGK 770
L + + WK P D+GG +T ++VE+ + + ++ VT + E
Sbjct: 30733 EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 30792
Query: 771 AYQFRILAVNSEGVSDPLETEEV-FAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDG 829
Y FR+ A N+ G+SDPLE V +P E PG +P +T VTK++ + W P DG
Sbjct: 30793 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDG 30852
Query: 830 GAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSV 889
GA + Y +E+R+K N W+ V + I+ T +V L+E EYEFRV N G + S
Sbjct: 30853 GAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSE 30912
Query: 890 PSSSVVAKD--PVKPPGLVQDL-HVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKE 946
S + K P++ P ++L +++ S+ +L + P + + + E +
Sbjct: 30913 ISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK-EIIAD 30971
Query: 947 WSKCTKIPISGTCY--TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKF 1004
K G + + + + +++RA N+ G G ++ K
Sbjct: 30972 GLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGG------SVSGTASLEVEVPAKI 31025
Query: 1005 DLSARLKSHMVVRA--GTALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQF 1060
L L+ V A G + I FSG P P + WQK D + G + +++ +
Sbjct: 31026 HLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSL 31085
Query: 1061 LI-NSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHS 1119
+ N +R D+G Y + +N FG + + + VAD P PP +++ + ++V LTW
Sbjct: 31086 VFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 31145
Query: 1120 PDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
+YI+ ++ A+TA + + +YTV L Y FRV+A N+ G S+
Sbjct: 31146 ASDGGSKITNYIV-EKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSK 31204
Query: 1180 PLDSRDTWLINKDQIQDLS 1198
P + + + +D+ + ++
Sbjct: 31205 PSEPSEPTITKEDKTRAMN 31223
Score = 243 bits (621), Expect = 7e-64
Identities = 306/1277 (23%), Positives = 500/1277 (39%), Gaps = 142/1277 (11%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARV-QGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
EF + + T EG AV V + NAK + W + +G I +S K + + L
Sbjct: 12286 EFTKPLEDQTVEEGATAVLECEVSRENAK--VKWFK-NGTEILKSKKYEIVADGRVRKLV 12342
Query: 127 LEPLTSDDSDNYKCIASN-----------DHADAIYTVSLLVTEGQEKMDFK-------- 167
+ T +D Y C A + H + + ++ L +E F+
Sbjct: 12343 IHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENA 12402
Query: 168 --KMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEM 225
K K A KK ++ + +++K D + E G+L L+E
Sbjct: 12403 KVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEE- 12461
Query: 226 KKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYD 285
EA+ K L + E T+ C E+ P ++IW KG E + G+Y+
Sbjct: 12462 ------EAV-FTKNLANIEVSETDTIKLVC--EVSKPGAEVIWYKGDEEI---IETGRYE 12509
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
+ G K +LVI N ++ DAG Y+ + R ++ V + +F+ + + +++ E + A
Sbjct: 12510 ILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKA 12569
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
F +SK+ WK + K L+ DKY++ DG L +KDA L D G + G
Sbjct: 12570 EFVCSISKESFPVQWKRDDKTLESGDKYDVIA--DGKKRVLVVKDATLQDMGTYVVMVGA 12627
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
A LT+ ++ V LK+ RVKE+ CE+ ++ +W ++ + + +KY
Sbjct: 12628 ARAAAHLTVIE-KLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYI 12686
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ + L I DA L D Y V ++ + S A + VEE + + D+
Sbjct: 12687 ILQKDLVYTLRIRDAHLDDQANYNV-SLTNHRGENVKSAANLIVEEEDLRIVEPLKDIET 12745
Query: 526 ATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
+N V W K+G+E+ + H L G EG+Y
Sbjct: 12746 MEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIV 12805
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
A +S A + I + PT +E L +T ++ + V WY++G
Sbjct: 12806 TAGQDKSVAELLIIEAPT---EFVEHLEDQTVTEFDDAVFSCQL---SREKANVKWYRNG 12859
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
E+ E ++ E+ L I +C +D +++ A + ++ +PPQ
Sbjct: 12860 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQ 12919
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAV--GKKSWIKIGEVDGKVTNFST 763
+ LE G+ V + KD + Q++ V G K + +GK+
Sbjct: 12920 ---DILEAPGADVVFLAELNKD---KVEVQWLRNNMVVVQGDKHQMMS---EGKIHRLQI 12970
Query: 764 NKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWN 823
++ ++R +A + E + E+ A I+ A Q V DV K +
Sbjct: 12971 CDIKPRDQGEYRFIAKDKEARAKL----ELAAAPKIKT---ADQDLVVDVGKPLTMVV-- 13021
Query: 824 APTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAG 883
P Y K W N +P+ TK T+D E T FR++ K
Sbjct: 13022 --------PYDAY-----PKAEAEWFKEN-EPLS-TK-TIDTTAEQTS--FRILEAKKGD 13063
Query: 884 PGQPSV-------PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSG 934
G+ + + + + PG V++L V+++ + +SLAW EP G G
Sbjct: 13064 KGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIG 13123
Query: 935 YILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQ-KYFFRIRAVNEAGVGEPVELDKGV 993
Y++E R K W T S +TV GL + +Y FR+ A N G GEPVE D V
Sbjct: 13124 YVVERRDIKRKTWVLATDRAESCE-FTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPV 13182
Query: 994 RAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD----------VIWQKDGV 1043
A P L+ + V R G +L PP+ VI +D
Sbjct: 13183 EARSKYDVPGPPLNVTITD--VNRFGVSLTWE-------PPEYDGGAEITNYVIELRDKT 13233
Query: 1044 PTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDI---HVRVAD---FPR 1097
+ +T + +R+ QN G + V+VAD P
Sbjct: 13234 SIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPS 13293
Query: 1098 PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSN-KY 1154
PP NL ++ ++V L W P +++ G YII + + W ++ Y
Sbjct: 13294 PPVNLTSSDQTQSSVQLKWE--PPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTY 13351
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPR 1214
VTGL G KY +RV A N+ G S+P + L D + + L ++ P
Sbjct: 13352 KVTGLEKGNKYLYRVSAENKAGVSDPSEILGP-LTADDAFVEPTMDLSAFKDGLEVIVPN 13410
Query: 1215 FVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPT 1274
+T L P T G PRPT T GD + + + S LVI
Sbjct: 13411 PITILVPST--------------GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISP 13456
Query: 1275 CTLKDSGDYSVLVENEL 1291
D G Y++ +EN +
Sbjct: 13457 SERSDKGIYTLKLENRV 13473
Score = 208 bits (529), Expect = 3e-53
Identities = 167/633 (26%), Positives = 273/633 (43%), Gaps = 66/633 (10%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
D P PP R+E +++ V + W P D+GG P+T + VER W++ ++ K
Sbjct: 13881 DPPGPPT-RLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD 13939
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVTKEA 817
T + + K Y+FR+LA N G P + TE + +PI+PP +P V DV K +
Sbjct: 13940 TTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTS 13999
Query: 818 VTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVI 877
V + W P DGGA + Y++E K G++ WV V + + T+ + GL+E EY FRV
Sbjct: 14000 VRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVR 14058
Query: 878 AVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGY 935
AVNKAG +PS PS V+ ++ + PP + L V + + ++ L W P + G P + Y
Sbjct: 14059 AVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNY 14118
Query: 936 ILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRA 995
I+E R K W + + T TV L E Y FR+ A N G + E++ V A
Sbjct: 14119 IVEKRDVRRKGW-QTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLA 14177
Query: 996 M-------PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD---------VIWQ 1039
PP A D++ R H PP + VI +
Sbjct: 14178 KDTFTTPGPPYALAVVDVTKR---------------HVDLKWEPPKNDGGRPIQRYVIEK 14222
Query: 1040 KDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADF---- 1095
K+ + T+ + + F + +++ +NE G +
Sbjct: 14223 KERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPT 14282
Query: 1096 --PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFS 1151
P PP +L + + + + W P + G Y + T W R
Sbjct: 14283 SPPSPPLDLHVTDAGRKHIAIAWK--PPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 14340
Query: 1152 N-KYTVT-GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
+ K+ V G++P ++Y RV A N IG SEP + + ++ KD + L+ ++
Sbjct: 14341 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISEN-VVAKDPDCKPTIDLETHDI--- 14396
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
V+ G+ ++ F P PTV+ +K + A+ + +
Sbjct: 14397 -------------IVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 14443
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L +P D+G Y++ +EN+LG +S + V
Sbjct: 14444 LEVPKSVRADAGIYTITLENKLGSATASINVKV 14476
Score = 208 bits (529), Expect = 3e-53
Identities = 143/432 (33%), Positives = 213/432 (49%), Gaps = 26/432 (6%)
Query: 762 STNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTIT 821
+ N+ + GK + + NS G V ++ PG +V +VTK +VT+T
Sbjct: 21920 NVNRFDSGK---YILTVENSSGSKSAFVNVRV-----LDTPGPPQDLKVKEVTKTSVTLT 21971
Query: 822 WNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNK 881
W+ P DGG+ + YIVE+R+ + V + T VD L E Y FRV+A N+
Sbjct: 21972 WDPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENE 22030
Query: 882 AGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEM 939
G G P+ + SV A + PPG + + D + +S+SL+W +P G GYI+EM
Sbjct: 22031 YGIGLPAETAESVKASERPLPPGKIT---LMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 22087
Query: 940 RAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP 999
+ + + +W+ C + ++ T+ GLI+ ++Y FR+ A NE G+ +P +L V A
Sbjct: 22088 QTKGSDKWATCATVKVTEA--TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV 22145
Query: 1000 AAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKG--RETITKSKNH 1057
P F L L + V AG L + F G P P V W KD VP K R ++N+
Sbjct: 22146 IPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN 22202
Query: 1058 SQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTW 1116
S I R D G Y + L N GEA ++V V D P PPT +++ E +++TL+W
Sbjct: 22203 SLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSW 22262
Query: 1117 NHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNE 1174
P + G + +YI+ KRD ST TW + V L G +Y FR+ A N
Sbjct: 22263 G--PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENR 22320
Query: 1175 IGDSEPLDSRDT 1186
G S L+S T
Sbjct: 22321 YGKSTYLNSEPT 22332
Score = 204 bits (518), Expect = 6e-52
Identities = 122/391 (31%), Positives = 190/391 (48%), Gaps = 6/391 (1%)
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N I P + + D+TK++V +TW P DGG+P+ GY+VE+R+ W V D +
Sbjct: 13483 NVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDFV 13541
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ TV L++ EY F+V A NK GPG+P+ V P P +++ D +
Sbjct: 13542 TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTA 13601
Query: 917 SSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+SI L W P G GYI+E + +W C + P++ T V GL E + Y +R
Sbjct: 13602 NSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGE-PVAETKMEVTGLEEGKWYAYR 13660
Query: 975 IRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPP 1034
++A+N G +P + ++A+ AP+ L +L + + V+AGT + + A +G P P
Sbjct: 13661 VKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP 13720
Query: 1035 DVIWQKDGVPTKG--RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV 1092
+ W K + K R TI S I +KRSD+G Y I N G A + V V
Sbjct: 13721 KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 13780
Query: 1093 ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSN 1152
D P PP + + + LTWN D +Y++ +R + W+ + V
Sbjct: 13781 LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDT 13840
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ T L+P ++Y FRV A N G EP+ +
Sbjct: 13841 NFKATKLIPNKEYIFRVAAENMYGVGEPVQA 13871
Score = 201 bits (512), Expect = 3e-51
Identities = 144/532 (27%), Positives = 249/532 (46%), Gaps = 31/532 (5%)
Query: 168 KMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKK 227
K K P K + V+ K +L + D + +T G L E K
Sbjct: 2826 KWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGE------YTAVVGQL----ECKA 2875
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K+ VE + I K +++ E T F+C E+ NV +W+K + + K+ +
Sbjct: 2876 KLFVETLHITKTMKNIEVPETKTASFEC--EVSHFNVPSMWLKNGVEIEMSE---KFKIV 2930
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G + L+I N + D+ Y+ G+ ++SA LTV P+ +K + E+ T F
Sbjct: 2931 VQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVT--PIMITSMLKDINAEEKDTITF 2988
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E+ ++ + ++ W NG E+K DK ++ + LTH+L I++ D+ +++ AG
Sbjct: 2989 EVTVNYEGISYKWLKNGVEIKSTDKCQMRTKK--LTHSLNIRNVHFGDAADYTFVAGKAT 3046
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A L ++ I+F ++K+++V E+ RA ECE++ D+T++W KD Q L + +
Sbjct: 3047 STATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQ 3106
Query: 468 HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT 527
E L+I ++SD G+YTVVA + STA + VE R ++S +V
Sbjct: 3107 KEKYVHRLLIPSTRMSDAGKYTVVAGGN------VSTAKLFVEGRDVRIRSIKKEVQVIE 3160
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEIT--DLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A + +N++ V+ W KDG EI + V + +H++ G+YTF
Sbjct: 3161 KQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTF 3220
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
A S ++++ P P VL+ L +TV+ G A G+P PK++WYK+
Sbjct: 3221 VAGRNRSSVTLYVNAPE--PPQVLQEL--QPVTVQSGKPARFCAVISGRPQPKISWYKEE 3276
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
++ + + L + ED+ + + KND+G AT + LSV
Sbjct: 3277 QLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3328
Score = 201 bits (512), Expect = 3e-51
Identities = 137/438 (31%), Positives = 208/438 (47%), Gaps = 44/438 (10%)
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
PG + +D+TK + +TW P DGG P+L Y++ERR+ G ++PV +
Sbjct: 14480 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENK-LSW 14538
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
TV L+ + EY FRV AVNK G G+ + V+A+DP +PP D+ V + + ++++
Sbjct: 14539 TVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTI 14598
Query: 922 AWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVN 979
W+ P G GYI+E A+ + W +C + + YT GL E ++Y FR+RA N
Sbjct: 14599 TWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAEN 14658
Query: 980 EAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQ 1039
AG+ EP +A+ P APK L++ + V+ G + + A+ SGSP P + W
Sbjct: 14659 AAGISEPSRATPPTKAVDPIDAPK----VILRTSLEVKRGDEIALDASISGSPYPTITWI 14714
Query: 1040 KDG------------------------------VPTKGRETITKS-KNHSQFLINSTKRS 1068
KD +P R +I S K SQ + + R
Sbjct: 14715 KDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP 14774
Query: 1069 DSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNT-VTLTWNHSPDVQEDGE 1127
D G+Y I ++N+ G A+ V V D P PP N +FE++ T V W D
Sbjct: 14775 DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEI 14833
Query: 1128 AHYIIMKRDAS--TATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+Y + K+D + + W + KY+VT L+ G++Y FRV A N G P S+
Sbjct: 14834 INYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKP 14893
Query: 1186 TWLINKDQIQDLSAKLKP 1203
L+ KD A KP
Sbjct: 14894 --LVAKDPFGPPDAPDKP 14909
Score = 201 bits (510), Expect = 5e-51
Identities = 167/595 (28%), Positives = 274/595 (46%), Gaps = 38/595 (6%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+ P +D L++ I V+ G +A I +PF+G+P P++TW ++ E T+ +V +E+G
Sbjct: 24020 EAPELD---LDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD--KVQIEKG 24074
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
+ L+I NC R D+G +LKL+N GS +A + + VLD P PPQ + E+
Sbjct: 24075 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQN-LAVKEVRKDSAF 24133
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAV 779
+ W+ P +GG V +++++R +K++ + K T+F + EG Y FR++A
Sbjct: 24134 LVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLTEGAIYYFRVMAE 24192
Query: 780 NSEGVSDPLET-EEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
N GV P+ET + V A P PPG + +TDV++ + ++ W P DGG+ VLGY+V
Sbjct: 24193 NEFGVGVPVETVDAVKAAEPPSPPGKVT---LTDVSQTSASLMWEKPEHDGGSRVLGYVV 24249
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
E + KG+ W V + + V GL EY+FRV A N+ G P V V+AKD
Sbjct: 24250 EMQPKGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 24307
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGT 958
P L + + S + L P G P E K+ T++ + T
Sbjct: 24308 LTIQPSLKLPFN-TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQ---TTRVNVEET 24363
Query: 959 C-YTVGGLIERQKYFF---RIRAVNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSH 1013
TV + E K F + A N AG E + + + PP +FD + +
Sbjct: 24364 ATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFD---EVSAD 24420
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
VV + A G + I +K T ++ + + I K +
Sbjct: 24421 FVVISWEP---PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQF 24477
Query: 1074 RILLQNEFGE-ARYDIHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE- 1127
RI +N +G+ A D + + P PP + + + + W H P V + G
Sbjct: 24478 RIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQW-HEP-VNDGGTK 24535
Query: 1128 -AHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
Y + +++ ++ W + + K+ TGL G +Y F+V A N +G +P
Sbjct: 24536 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKP 24590
Score = 200 bits (509), Expect = 7e-51
Identities = 157/596 (26%), Positives = 262/596 (43%), Gaps = 26/596 (4%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+PP + +L+A A +KVG T + +G P PKVTW K+ + + R+ +
Sbjct: 17214 EPPEL---ILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPV 17270
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
+ L I N ED G+ L ++N GS T ++ + VLD+P PP+ +E E+ +
Sbjct: 17271 GSK--LEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRD-LEVSEIRKDSCY 17327
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAV 779
+ WK P D+GG +T ++VERR V W + K ++F+ + + EG Y FR+ A
Sbjct: 17328 LTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH-LNEGNQYLFRVAAE 17386
Query: 780 NSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
N G +ET + + A +P+ PPG DV K V++ WN P +DGG+P+ GY+V
Sbjct: 17387 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 17446
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
E +++G+ W+ + +C V GL + Y FRV A N G G P + + ++
Sbjct: 17447 EYQEEGTQDWIKFK--TVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDT-TIPIECQE 17503
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDP-PSGYILEMRAEDTKEWSKCTKIPI 955
+ PP + D+ + + R PA G P P+ +E + +
Sbjct: 17504 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 17563
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
+ T+ + R ++I N AG + V + V +P P ++ HM
Sbjct: 17564 FSSVLTIKNCLRRDTGEYQITVSNAAG-SKTVAVHLTVLDVPGPPTGPINILDVTPEHMT 17622
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
+ GSP + I +K ++ + ++ I ++ V+R+
Sbjct: 17623 ISWQPP----KDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRV 17678
Query: 1076 LLQNEFG-----EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHY 1130
+N+ G ++ + P PP + + N T++W P
Sbjct: 17679 RAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWT-LPKSDGGSPITG 17737
Query: 1131 IIMKRDASTATWYTAAERVFSN-KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
M+R T W + ++ K+ VTGL G Y FRV A N G S+P S D
Sbjct: 17738 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSD 17793
Score = 196 bits (497), Expect = 2e-49
Identities = 174/653 (26%), Positives = 280/653 (42%), Gaps = 42/653 (6%)
Query: 567 VHKLIFPSMGPEHEGKYTFRAKGTESEASV---------FIADPPTIDPSVLEALAAHAI 617
V +L + G E KY +R E++A V AD ++P++ + +
Sbjct: 13346 VPELTYKVTGLEKGNKYLYRVSA-ENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGL 13404
Query: 618 TVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGL 677
V V + I VP G P P TW + +RV M+ A L IS R D G+
Sbjct: 13405 EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGI 13464
Query: 678 ILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFI 737
LKL+N + + + ++V+ RP P+ ++F +++ VH+ W+ P D+GG P+T ++
Sbjct: 13465 YTLKLENRVKTISGEIDVNVIARPSAPK-ELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 13523
Query: 738 VERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAG 796
VE+R V +K+W K+ + + F+ + +GK Y F++ A N G +P +E V
Sbjct: 13524 VEKREVSRKTWTKVMDFVTDL-EFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMS 13582
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
P P + D T ++ +TW+ P DGG+ + GYIVER +GS+ WV +P+
Sbjct: 13583 TPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG-EPV 13641
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
TK V GL E Y +RV A+N+ G +PS P+ + A D + P + D+ +
Sbjct: 13642 AETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLT 13701
Query: 917 SSISLAWREPAE-GDPPSGYILEMRAEDTKEWSK---CTKIPISGTCYTVGGLIERQKYF 972
PA P I +A+ + K +P T T+
Sbjct: 13702 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST-VTIVDSKRSDTGT 13760
Query: 973 FRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSP 1032
+ I AVN G V + PPAA FD++ ++ GS
Sbjct: 13761 YIIEAVNVCGRATAVVEVNVLDKPGPPAA--FDITDVTNESCLLTWNPP----RDDGGSK 13814
Query: 1033 PPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---------- 1082
+ + ++ ++ ++ + + F + ++R+ +N +G
Sbjct: 13815 ITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPI 13874
Query: 1083 EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATW 1142
A+Y D P PPT L + + VTLTW D Y + + D T W
Sbjct: 13875 TAKYQF-----DPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKW 13929
Query: 1143 YTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQI 1194
+ V Y V GL +KY FRV+A N G +P S + LI KD I
Sbjct: 13930 VRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI-KDPI 13981
Score = 196 bits (497), Expect = 2e-49
Identities = 143/520 (27%), Positives = 238/520 (45%), Gaps = 28/520 (5%)
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
L+ P+PP E L+++ S V + W PKD+GG VT + +ER+ W++ +
Sbjct: 30326 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 30385
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKE 816
T ++ + YQFRI+A N G+S+ E V +P + P + ++ ++K+
Sbjct: 30386 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 30445
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
+VT+ W P DGG +LGY VE R+ G + W NK+ I+ + T+ GLLE TEYEFRV
Sbjct: 30446 SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRV 30505
Query: 877 IAVNKAGPGQPSVPSSSVVAK-DPVKPPGLVQDLH-----VSDSSNSSISLAWREPAEGD 930
A N+ G +P + S+ K + PG+ +++ + +++ S + R
Sbjct: 30506 FAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGR------ 30559
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKY--FFRIRAVNEAGVGEPVE 988
P I R S+ K+ G +T+ + E Q+ + A NE G E
Sbjct: 30560 -PLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG-----E 30613
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGR 1048
++ + + A P+F LK G+ L +H + G P P + W +
Sbjct: 30614 VETSSKLLLQ-ATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNS 30672
Query: 1049 ETIT-KSKNHSQFLI--NSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLF 1105
E IT ++ H L+ N +++ +G Y++ L N FG + V + D P PT +
Sbjct: 30673 ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVI 30732
Query: 1106 EEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDAST-ATWYTAAERVFSNKYTVTGLLPGR 1163
E + N+ ++W D +Y++ K +A A W + + + L
Sbjct: 30733 EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 30792
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203
YYFRV A+N G S+PL+ +I K + A KP
Sbjct: 30793 GYYFRVSAQNTFGISDPLEVSSVVII-KSPFEKPGAPGKP 30831
Score = 195 bits (496), Expect = 2e-49
Identities = 163/617 (26%), Positives = 271/617 (43%), Gaps = 43/617 (6%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ E ++ + + W P +GG + +IVERR + WIK +
Sbjct: 21655 PDPPKNP-EVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR 21713
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVT 819
+ + + EG Y+FRI+A N+ G+S P T + A + + PG P+V D ++ +++
Sbjct: 21714 YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSIS 21773
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLEDTEYEFRVIA 878
I WN P DGG+ + GY+VE + W V ++ T T+ GL E+ EY+ R+ A
Sbjct: 21774 IAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYA 21833
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPG--LVQDLHVSDSSNSSISLAWREPAEGDPPSGYI 936
+N G G+P++ + A+D + PP L DL + + +L P +G P
Sbjct: 21834 MNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPE-- 21891
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
++ + + K + S + G + R I V + + ++ VR +
Sbjct: 21892 VKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVN--VRVL 21949
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKS 1054
P P+ LK V + L GS + I +K K T+ +
Sbjct: 21950 DTPGPPQ-----DLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATN 22004
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNT 1111
+ + + ++ + S +R+L +NE+G A V+ ++ P PP + L + N+
Sbjct: 22005 CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS 22064
Query: 1112 VTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFR 1168
V+L+W + DG + YI+ + + W T A V + T+TGL+ G +Y FR
Sbjct: 22065 VSLSWEKP---EHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFR 22120
Query: 1169 VVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQ 1228
V A+NE G S+P + LS P KD P F TVL G+
Sbjct: 22121 VSAQNEKGISDP--------------RQLSV---PVIAKDLVIPPAFKLLFNTFTVLAGE 22163
Query: 1229 DCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVE 1288
D + F+G P P VT +K +V + ++ ST L I +D G Y V +
Sbjct: 22164 DLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLT 22223
Query: 1289 NELGKDRSSCTLTVYDK 1305
N G+ + + V DK
Sbjct: 22224 NSAGEAIETLNVIVLDK 22240
Score = 193 bits (491), Expect = 8e-49
Identities = 124/393 (31%), Positives = 189/393 (48%), Gaps = 9/393 (2%)
Query: 799 IEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG 858
++ PG +V+++ K++ +TW P DGG+ + Y+VERR S W P++ +
Sbjct: 17307 LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKK 17366
Query: 859 TKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSS 918
+ L E +Y FRV A N+ G G + A DP+ PPG +DLH D +
Sbjct: 17367 SHFAKH-LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTE 17425
Query: 919 ISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIR 976
+SL W +P G P +GY++E + E T++W K + + V GL + + Y FR++
Sbjct: 17426 VSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTV--TNLECVVTGLQQGKTYRFRVK 17483
Query: 977 AVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
A N G+G P + + P +L +L +VV+AGT + A G P P
Sbjct: 17484 AENIVGLGLP-DTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTA 17542
Query: 1037 IWQKDGVPTKGRETIT-KSKNHSQFL-INSTKRSDSGVYRILLQNEFGEARYDIHVRVAD 1094
W DG K E T ++ N S L I + R D+G Y+I + N G +H+ V D
Sbjct: 17543 KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD 17602
Query: 1095 FPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNK 1153
P PPT + + + P +T++W D +YI+ K+D TW + K
Sbjct: 17603 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 17662
Query: 1154 YTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDT 1186
+ L G +Y FRV A N+IG PLDS T
Sbjct: 17663 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPT 17695
Score = 193 bits (491), Expect = 8e-49
Identities = 194/806 (24%), Positives = 335/806 (41%), Gaps = 105/806 (13%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
W KDG + G+++ Q + L S+ + G YT A+ + S TI
Sbjct: 19329 WKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSA------TIK 19382
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKD----GMEVT-----EEERVSM 656
VL+ K G A +K+ ++W G E+T + E
Sbjct: 19383 LKVLD---------KPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRP 19433
Query: 657 ERGEDQALLTISNC-----VREDSGLILLKLKNDHGSATATL-HLSVLDRPKPPQGRVE- 709
+ A + I++C + + +N +G ++ P P GR +
Sbjct: 19434 NWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 19493
Query: 710 --FLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVE 767
++ + + WK P D+GG P+T +++E+R +W K+ ++
Sbjct: 19494 PVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQ 19553
Query: 768 EGKAYQFRILAVNSEGVSDPLETEEV-FAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
EG Y+FR+ A+N G P + + +A +P PPG + P+V D T+ +V+++W P
Sbjct: 19554 EGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 19613
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVN-KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPG 885
DGG+P++GY+VE ++ S+ WV N +Q T+ V GL+EDT+Y+FRV AVNK G
Sbjct: 19614 YDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYS 19673
Query: 886 QPSVPSSSVVAKDPVKPPG--LVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAED 943
PS KD + PP L DL + + +++ P +G PP
Sbjct: 19674 DPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKIT------- 19726
Query: 944 TKEWSKCTKIPISGTCYTVGGLIERQKY--FFRIRAVNEAGVGEPV----------ELDK 991
WSK P +G I+ + F R VN+ G+ + E
Sbjct: 19727 ---WSK----PNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTI 19779
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI 1051
V+ + P P ++ +K A GSP + + QK K T+
Sbjct: 19780 VVKVLDTPGPP---VNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 19836
Query: 1052 TKSKNHSQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRLFE 1106
T + + F + + + S +R+ +NE+G E R V+ + P P +L++
Sbjct: 19837 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTPGPVVDLKVRS 19894
Query: 1107 EVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTAT--WYTAAERVFSNKYTVTGLLPGRK 1164
++ ++ W DG + I D T W + + S +Y+ L G++
Sbjct: 19895 VSKSSCSIGWKKP---HSDGGSRIIGYVVDFLTEENKWQRVMKSL-SLQYSAKDLTEGKE 19950
Query: 1165 YYFRVVARNEIGDSEPLDSRDTWLINKDQI--QDLSAKLKP---YEKKDWRHAPRFVTPL 1219
Y FRV A NE G+ P + ++ +D + DL K P Y K+ + R P+
Sbjct: 19951 YTFRVSAENENGEGTP---SEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF-RLKIPI 20006
Query: 1220 KPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKD 1279
K G P P+V+ KG+ + +++ S++ TL++ C D
Sbjct: 20007 K-----------------GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSD 20049
Query: 1280 SGDYSVLVENELGKDRSSCTLTVYDK 1305
+G Y++ ++N G + ++ V K
Sbjct: 20050 AGKYTITLKNVAGTKEGTISIKVVGK 20075
Score = 193 bits (490), Expect = 1e-48
Identities = 138/458 (30%), Positives = 214/458 (46%), Gaps = 43/458 (9%)
Query: 749 IKIGEVDGKV------------TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
+K G+VDG++ T+ + V + ++ + NS G T V
Sbjct: 22974 VKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRV--- 23030
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
++ P +VT++TK++V+ITW P DGG+ + YIVE+R+ + V +
Sbjct: 23031 --LDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTN-C 23087
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+D L E Y FRV A N+ G G P+ + + + +PPG + V D +
Sbjct: 23088 HKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKIT---VDDVTR 23144
Query: 917 SSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+S+SL+W +P G YI+EM+A+ +++WS+C ++ T L + ++Y FR
Sbjct: 23145 NSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVIT--NLTQGEEYLFR 23202
Query: 975 IRAVNEAGVGEPVELDKGVRA----MPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSG 1030
+ AVNE G +P L + A + P P F S V+ G L I SG
Sbjct: 23203 VVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAF-------SSYSVQVGQDLKIEVPISG 23255
Query: 1031 SPPPDVIWQKDGVPTK--GRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDI 1088
P P + W KDG+P K R +T S + + I T + D G Y I + N G+ I
Sbjct: 23256 RPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASI 23315
Query: 1089 HVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDG--EAHYIIMKRDASTATWYTA 1145
+ D P PP F++V ++TL+WN P + G +YI+ KRD +T W
Sbjct: 23316 EIVTLDKPDPPKGPVKFDDVSAESITLSWN--PPLYTGGCQITNYIVQKRDTTTTVWDVV 23373
Query: 1146 AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ V VT L G +Y FR+ A N G S L+S
Sbjct: 23374 SATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALES 23411
Score = 191 bits (486), Expect = 3e-48
Identities = 152/474 (32%), Positives = 218/474 (45%), Gaps = 34/474 (7%)
Query: 730 GRPVTQF-IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVS--- 785
G P+ F IV R K +W K+G +D V + V+ F ++ ++ S
Sbjct: 18621 GCPIRLFAIVRGRPAPKVTWRKVG-IDNVVRKGQVDLVD---TMAFLVIPNSTRDDSGKY 18676
Query: 786 -----DPLETEEVFAG-NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE 839
+P + VF ++ PG S +V+DVTK + ++W P DGG+ V YIVE
Sbjct: 18677 SLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVE 18736
Query: 840 RRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDP 899
+R+ W V + ++ T V L+ EY FRV AVN+ GPG P+ V+A DP
Sbjct: 18737 KREADRKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 18795
Query: 900 VKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAED--TKEWSKCTKIPI 955
+ P + L V++ + +S +LAW P G GYI R E+ W++ + +
Sbjct: 18796 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYS--VV 18853
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
V GL E +KY FR+ A N GV P E + A PK + +
Sbjct: 18854 KDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI----LMPEQIT 18909
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
++AG L I A G P P W+K D V T + K+ + S +I R DSG Y
Sbjct: 18910 IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYY 18969
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEA---H 1129
+ +N G I V V D P PP ++ + +L+W H P EDG + +
Sbjct: 18970 SLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSW-HIP--LEDGGSNITN 19026
Query: 1130 YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
YI+ K D S W TA V V L+PG++Y FRV A N G SEPL S
Sbjct: 19027 YIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTS 19080
Score = 191 bits (485), Expect = 4e-48
Identities = 165/599 (27%), Positives = 252/599 (42%), Gaps = 54/599 (9%)
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L+A I V G I GKP P VTW + E T + ++E + + I
Sbjct: 16526 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMN--ERTLPQEATIETTAISSSMVIK 16583
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
NC R G+ L KN+ G T+ + VLD P P L+ + W +P+D+
Sbjct: 16584 NCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDD 16643
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG P+T +++E+R +++W + + N + + +GKAY FRI A NS G+ +
Sbjct: 16644 GGSPITNYVIEKRESDRRAWTPVTYTVTR-QNATVQGLIQGKAYFFRIAAENSIGMGPFV 16702
Query: 789 ETEEVFA-GNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNL 847
ET E PI P +V +VTK VT+TWN P DGG+ ++ Y++E R G+
Sbjct: 16703 ETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 16762
Query: 848 WVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
+ V D + K TV GL E YE+RV AVN G G+PS + + KD + PP L
Sbjct: 16763 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 16822
Query: 908 DLH--VSDSSNSSISLAWREPAEGDPPSGYILEMR--AEDTKEWSKCTKIPI-------- 955
D ++ + +L R + P + + ED + K T +
Sbjct: 16823 DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAK 16882
Query: 956 ---SGT-CYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLK 1011
SG C V +K F ++ V+ G PP FD K
Sbjct: 16883 RSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--------------PPVGPVSFD--EVTK 16926
Query: 1012 SHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSG 1071
+MV+ L GS + I +K V +T + + ++
Sbjct: 16927 DYMVISWKPPL----DDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY 16982
Query: 1072 VYRILLQNEFG--------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQ 1123
++RI +N +G + RV D P P + E ++ +TWN D
Sbjct: 16983 IFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPI---VTEVTKDSALVTWNKPHDGG 17039
Query: 1124 EDGEAHYIIMKRDASTATWYTAAERVFS--NKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
+ +YI+ KR+ + W + K+ V LL G +Y FRV A NEIG +P
Sbjct: 17040 KP-ITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDP 17097
Score = 191 bits (484), Expect = 5e-48
Identities = 126/394 (31%), Positives = 187/394 (47%), Gaps = 11/394 (2%)
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N ++ PG +VT+VTKE TI+W P +GG+ + +IVE RK W V D
Sbjct: 17997 NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVT 18056
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ + LL + EY FRV A NK G G + ++A +P+ PG ++LH++D
Sbjct: 18057 K--RLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGK 18114
Query: 917 SSISLAWREP--AEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+ + L WR P G P Y +E R + + +W + K I T Y V +E Q Y FR
Sbjct: 18115 TFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFR 18174
Query: 975 IRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPP 1034
++ NE G + V+ ++ V P DL +L + V+AG + + A G P P
Sbjct: 18175 VQTKNEGGESDWVKTEE-VVVKEDLQKPVLDL--KLSGVLTVKAGDTIRLEAGVRGKPFP 18231
Query: 1035 DVIWQKDGVPT----KGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHV 1090
+V W KD T R I + S+F + KRSD G Y + N G V
Sbjct: 18232 EVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATV 18291
Query: 1091 RVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF 1150
V D P P NL++ + + T+ W+ D +YI+ K + W T + V
Sbjct: 18292 NVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVL 18351
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ TVT L+ G +Y FRV A N+IG P +S+
Sbjct: 18352 TPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESK 18385
Score = 190 bits (482), Expect = 9e-48
Identities = 129/462 (27%), Positives = 213/462 (46%), Gaps = 48/462 (10%)
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLE 128
FV +PQ + E A F A+V G+ P++ W + + + ++F E L++
Sbjct: 8456 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIR 8515
Query: 129 PLTSDDSDNYKCIASNDHADAIYTVSLLVTEG--QEKM--DFKKMLKKRAPPAPKKKQKK 184
T DS Y+C+A N+H + V+L V E QEK+ D + MLKK P KK +
Sbjct: 8516 DTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKT--PILKKGAGE 8573
Query: 185 VANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVE-------------- 230
E +++E+L V K++EK YG TDFRGLL+ + +K+ E
Sbjct: 8574 -EEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERS 8632
Query: 231 --------------------VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIK 270
E + ++K +E++ D VF+ +++ P +K+ W K
Sbjct: 8633 ERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYK 8692
Query: 271 GTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKF 330
GTE L K+++ G ++ L + N + D G Y L G SA+LTV++ +
Sbjct: 8693 GTEKLEPS---DKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLTVIEPAWE- 8748
Query: 331 LGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKD 390
++ V + E QT + S W NG+ LK +++ V H L I D
Sbjct: 8749 -RHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVEHK--VHKLTIAD 8805
Query: 391 ARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLR 450
R D G+++ + +L A+L I+ PI+F ++N+ V E A ECE++ D +
Sbjct: 8806 VRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVT 8865
Query: 451 WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVA 492
W K L KY+ ++G+ + I + D G Y+V+A
Sbjct: 8866 WYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIA 8907
Score = 189 bits (481), Expect = 1e-47
Identities = 158/580 (27%), Positives = 258/580 (44%), Gaps = 42/580 (7%)
Query: 619 VKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLI 678
V+ G + + + ++G+P P W K ++ R + + + LT+ NC R D+G
Sbjct: 28369 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL--RADIHTTDSFSTLTVENCNRNDAGKY 28426
Query: 679 LLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIV 738
L ++N+ GS + T + VLD P PP G + F +++ + W AP +GG + ++V
Sbjct: 28427 TLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGARIHHYVV 28485
Query: 739 ERRAVGKKSWIKIGEVDGKVTN--FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
E+R ++SW I E K T F N + EG Y FR+ AVN GV +P E E
Sbjct: 28486 EKREASRRSWQVISE---KCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVA 28542
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
E P + V D +K + + W P DGG+ + GY++E R+KGS+ WV
Sbjct: 28543 T--EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH--T 28598
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPP-----GLVQDLHV 911
+ TV+ L+E TEYEFRV A N AG +P SSV+ K+P P G+ L +
Sbjct: 28599 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQL-I 28657
Query: 912 SDSSNSSISLAWREPAEGDPP---SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ + S ++ P G P + + EMR ++T S T T TV +
Sbjct: 28658 TCKAGSPFTI--DVPISGRPAPKVTWKLEEMRLKETDRVSITT--TKDRTTLTVKDSMRG 28713
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAF 1028
+ + N AGV + + V P P ++S+ V+ G
Sbjct: 28714 DSGRYFLTLENTAGV-KTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEP----KDG 28768
Query: 1029 SGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR-YD 1087
G+ + I +K T + + S +Q + + +R+ +N FG ++ +
Sbjct: 28769 GGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE 28828
Query: 1088 IHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTA 1140
+A+ P PT ++ N +++ W + DG + Y + K++ +T
Sbjct: 28829 SAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWE---EPYHDGGSKIIGYWVEKKERNTI 28885
Query: 1141 TWYTAAE-RVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
W + Y VTGL+ G +Y FR A N G S+
Sbjct: 28886 LWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSK 28925
Score = 189 bits (480), Expect = 2e-47
Identities = 192/770 (24%), Positives = 305/770 (39%), Gaps = 73/770 (9%)
Query: 570 LIFPSMGPEHEGKYTFRAKGTESEAS------VFIADPPTIDPSVLEALAAHAITVKVGH 623
L+ P G YT A AS V P + P E+++A +T+
Sbjct: 16181 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSW-- 16238
Query: 624 TAHIKVPFRGKPLPKVTWYK-DGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKL 682
P + K+T Y + E + V + + TI + + +
Sbjct: 16239 -----FPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMA 16293
Query: 683 KNDHGSA--------TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
+N +G TA SV P P ++ + + + W+ P+ +GG PVT
Sbjct: 16294 QNKYGIGEPLDSEPETARNLFSVPGAPDKPT----VSSVTRNSMTVNWEEPEYDGGSPVT 16349
Query: 735 QFIVERRAVGKKSWIKIGEVDGKV----TNFSTNKVEEGKAYQFRILAVNSEGVSDP-LE 789
+ +E + K W ++ K ++ + EG YQFR+ A+N+ GV L
Sbjct: 16350 GYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLP 16409
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
++ A +PI PPG P+VTD TK + + W+ P +DGG+ V GYIVE +++G W
Sbjct: 16410 SDPATARDPIAPPG-PPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWE 16468
Query: 850 PVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDL 909
++GTK V GL E Y+FRV AVN AG G+P + + KD + P L D
Sbjct: 16469 KGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDA 16528
Query: 910 HVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIE 967
V D R A G PP M + + IS + +
Sbjct: 16529 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSM-VIKNCQR 16587
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
+ + + A NEAG + + V +P P F +H + L +
Sbjct: 16588 SHQGVYSLLAKNEAGERKKTII-VDVLDVPGPVGTPF------LAHNLTNESCKLTWFSP 16640
Query: 1028 FS--GSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG--- 1082
GSP + + +K + +T + + + + +RI +N G
Sbjct: 16641 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 16700
Query: 1083 --EARYDIHVRVA-DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDA 1137
E + +R P P +L + E NTVTLTWN P + G +Y++ R
Sbjct: 16701 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWN--PPKYDGGSEIINYVLESRLI 16758
Query: 1138 STATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQD 1196
T ++ + + S KYTV GL G Y +RV A N +G +P
Sbjct: 16759 GTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP---------------- 16802
Query: 1197 LSAKLKPYEKKDWRHAPRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITA 1255
S KP KD P + +R G+ +T + G P+P V+ +K + ++
Sbjct: 16803 -SFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 16861
Query: 1256 NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+ + +T L DSG Y V+VEN G + C + V D+
Sbjct: 16862 DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 16911
Score = 188 bits (477), Expect = 3e-47
Identities = 110/321 (34%), Positives = 176/321 (54%), Gaps = 12/321 (3%)
Query: 590 TESEASVFIADP---PTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
+E +V DP PTID L H I V G I VPFR P+P V+W+KDG
Sbjct: 14372 SEISENVVAKDPDCKPTID------LETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGK 14425
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
EV +R++M+ A L + VR D+G+ + L+N GSATA++++ V+ P P +
Sbjct: 14426 EVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKD 14485
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
++ +++ S + W+ P+ +GG P+ +++ERR G++++I + + K++ + +
Sbjct: 14486 -IKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLI 14544
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
G+ Y FR+ AVN G + +E + V A +P +PP +V + T EA+TITW P
Sbjct: 14545 PNGE-YFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPP 14603
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPG 885
DGG+ ++GYI+E+ KG W N+ + T GL E EY+FRV A N AG
Sbjct: 14604 LYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGIS 14663
Query: 886 QPSVPSSSVVAKDPVKPPGLV 906
+PS + A DP+ P ++
Sbjct: 14664 EPSRATPPTKAVDPIDAPKVI 14684
Score = 187 bits (475), Expect = 6e-47
Identities = 164/601 (27%), Positives = 274/601 (45%), Gaps = 52/601 (8%)
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
PP I+ L+A +T++ T + VP +G+P P+V W +D E ++ S+E
Sbjct: 21857 PPEIE---LDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGE--SLDKASIESTS 21911
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHM 720
LL + N R DSG +L ++N GS +A +++ VLD P PPQ ++ E++ + V +
Sbjct: 21912 SYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQD-LKVKEVTKTSVTL 21970
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W P +GG + +IVE+R +K++ + K T++ ++++EG +Y FR+LA N
Sbjct: 21971 TWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHK-TSWKVDQLQEGCSYYFRVLAEN 22029
Query: 781 SEGVSDPLET-EEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE 839
G+ P ET E V A PPG + + DVT+ +V+++W P DGG+ +LGYIVE
Sbjct: 22030 EYGIGLPAETAESVKASERPLPPG---KITLMDVTRNSVSLSWEKPEHDGGSRILGYIVE 22086
Query: 840 RRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDP 899
+ KGS+ W ++ T+ T+ GL++ EY FRV A N+ G P S V+AKD
Sbjct: 22087 MQTKGSDKWATC--ATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDL 22144
Query: 900 VKPPGLV-----------QDLHVSDS--SNSSISLAWREPAEGDPPSGYILEMRAEDTKE 946
V PP +DL V + ++ W + + P + AE T+
Sbjct: 22145 VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWH---KDNVPLKQTTRVNAESTEN 22201
Query: 947 WSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE-LDKGVRAMPPPAAPKFD 1005
S T I C G + ++ N A GE +E L+ V P P
Sbjct: 22202 NSLLT---IKDACREDVG-------HYVVKLTNSA--GEAIETLNVIVLDKPGPPTGPVK 22249
Query: 1006 LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINST 1065
+ + + G GS + I +K T + ++ + +
Sbjct: 22250 MDEVTADSITLSWGPP----KYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRL 22305
Query: 1066 KRSDSGVYRILLQNEFGEARY-DIHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSP 1120
K +RI +N +G++ Y + VA + P PP + +++ + WN
Sbjct: 22306 KTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPI 22365
Query: 1121 DVQEDGEAHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
Y + +++ ++ W + + K+ TGL G +Y FRV A N +G +
Sbjct: 22366 SDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGK 22425
Query: 1180 P 1180
P
Sbjct: 22426 P 22426
Score = 187 bits (474), Expect = 8e-47
Identities = 184/687 (26%), Positives = 294/687 (42%), Gaps = 94/687 (13%)
Query: 560 QIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT------------ESEASVFIADPPTIDPS 607
+I K + + F G +Y FR K ES + I PP ++
Sbjct: 17852 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVE-- 17909
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
L+ ITV+VG T I +G+P P +TW K+G + E+RV + + + L I
Sbjct: 17910 -LDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQI 17968
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKD 727
VR D G ++ KN G A + ++VLDRP P Q +C + W+ P D
Sbjct: 17969 KEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCT-ISWENPLD 18027
Query: 728 NGGRPVTQFIVERRAVGKKSW-IKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSD 786
NGG +T FIVE R +K W I +V ++ + E Y FR+ A N GV
Sbjct: 18028 NGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNE---YYFRVCAENKVGVGP 18084
Query: 787 PLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGS 845
+ET+ + A NPI+ PG + D K V + W P DGG+P L Y VERR KGS
Sbjct: 18085 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 18144
Query: 846 NLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL 905
+ W V+K I+ T VD +E+ YEFRV N+ G V + VV K+ ++ P
Sbjct: 18145 DDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVVKEDLQKP-- 18201
Query: 906 VQDLHVSD----SSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT 961
V DL +S + +I L E P + + +D + ++ ++ I +
Sbjct: 18202 VLDLKLSGVLTVKAGDTIRL---EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADS 18258
Query: 962 VGGLIERQKYF----FRIRAVNEAG----------VGEP----------VELDKGVRAMP 997
+ + K + + A N AG + +P V D+
Sbjct: 18259 SKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWD 18318
Query: 998 PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNH 1057
P P+ D ++++++ + T + + +S + V T G T+T+
Sbjct: 18319 P---PEDDGGCEIQNYILEKCETKRMVWSTYSAT-----------VLTPG-TTVTRLIEG 18363
Query: 1058 SQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRLFEEVPNTV 1112
+++ ++R+ +N+ G E++ I D P P + + +
Sbjct: 18364 NEY-----------IFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEM 18412
Query: 1113 TLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGRKYYFRV 1169
T+ WN P + G++ Y + K++ + W + + V LLP +Y FRV
Sbjct: 18413 TVVWN--PPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRV 18470
Query: 1170 VARNEIGDSEP-LDSRDTWLINKDQIQ 1195
A NEIG EP L SR ++ KD I+
Sbjct: 18471 KAENEIGIGEPSLPSRP--VVAKDPIE 18495
Score = 185 bits (470), Expect = 2e-46
Identities = 136/460 (29%), Positives = 206/460 (44%), Gaps = 20/460 (4%)
Query: 730 GRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE 789
GRP + R ++I E T S + + A ++ + NS G
Sbjct: 24050 GRPTPEITWSREEGEFTDKVQI-EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 24108
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
T +V ++ PG V +V K++ + W P DGGA V Y++++R+ +
Sbjct: 24109 TVKV-----LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYA 24163
Query: 850 PVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDL 909
V+ T V+ L E Y FRV+A N+ G G P +V A +P PPG V
Sbjct: 24164 NVSSK-CSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVT-- 24220
Query: 910 HVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIE 967
++D S +S SL W +P G GY++EM+ + T++WS + + T GL
Sbjct: 24221 -LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVT--GLSS 24277
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
Q+Y FR++A NE G +P L V A P L S ++AG L I
Sbjct: 24278 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYS---IQAGEDLKIEIP 24334
Query: 1028 FSGSPPPDVIWQKDGVPTKG--RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR 1085
G P P++ W KDG P K R + ++ + I + D G Y + N G A
Sbjct: 24335 VIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTAT 24394
Query: 1086 YDIHVRVADFPRPPTNLRLFEEVP-NTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
++ V V + P PP F+EV + V ++W ++YI+ KRD +T TW+
Sbjct: 24395 ENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHM 24454
Query: 1145 AAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ V +T L G +Y FR+ A N G S PLDS+
Sbjct: 24455 VSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSK 24494
Score = 184 bits (467), Expect = 5e-46
Identities = 129/458 (28%), Positives = 206/458 (44%), Gaps = 17/458 (3%)
Query: 732 PVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE 791
P + + R + +++ I+ + + + + +G + +LA N G E +
Sbjct: 16554 PTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV---YSLLAKNEAG-----ERK 16605
Query: 792 EVFAGNPIEPPGFASQPQVT-DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP 850
+ + ++ PG P + ++T E+ +TW +P DGG+P+ Y++E+R+ W P
Sbjct: 16606 KTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTP 16665
Query: 851 VNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLH 910
V + TV GL++ Y FR+ A N G G S ++V ++P+ P +DL
Sbjct: 16666 VTYT-VTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE 16724
Query: 911 VSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
V + + ++++L W P G Y+LE R T+++ K T + YTV GL E
Sbjct: 16725 VKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEG 16784
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAF 1028
Y +R+ AVN G G+P K + A P L R K + +R G A + +
Sbjct: 16785 DTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDK--LTIRVGEAFALTGRY 16842
Query: 1029 SGSPPPDVIWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
SG P P V W KD V R I + KRSDSG Y ++++N G +
Sbjct: 16843 SGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKG 16902
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNT-VTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTA 1145
V V D P PP F+EV + ++W D +YII K++ W
Sbjct: 16903 FCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV 16962
Query: 1146 AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
V+ LL G+ Y FR+ A N G S+PL S
Sbjct: 16963 TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVS 17000
Score = 183 bits (465), Expect = 8e-46
Identities = 173/660 (26%), Positives = 266/660 (40%), Gaps = 74/660 (11%)
Query: 582 KYTFRAKGT----ESEASVFIADPPTID----PSVLEALAAH-AITVKVGHTAHIKVPFR 632
KY FR K ESE S + P D P V + A + K G I +
Sbjct: 15776 KYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIK 15835
Query: 633 GKPLPKVTW---------YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLK 683
G+P PK +W KDG+ E+ +E E+ +++ I C R +G + K
Sbjct: 15836 GRPTPKSSWEFDGKAKKAMKDGVHDIPED-AQLETAENSSVIIIPECKRSHTGKYSITAK 15894
Query: 684 NDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAV 743
N G TA + V+D P PP+ GSC + WK P D+GG + +++E+R +
Sbjct: 15895 NKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSC-RLSWKMPDDDGGDRIKGYVIEKRTI 15953
Query: 744 GKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLET-EEVFAGNPIEPP 802
K+W K+ G T + + E + Y FR+ A N G+ P+ET + A +PI PP
Sbjct: 15954 DGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIYPP 16012
Query: 803 GFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE-------RRKKGSNLWVPVNKDP 855
+ ++ +TK V ++W P DGG+PV YIVE KK + W NK
Sbjct: 16013 DPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEA--WRQCNKRD 16070
Query: 856 IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPG--LVQDLHVSD 913
++ + TV+ L+E EYEFRV AVN AG +PS + P PP L + + V +
Sbjct: 16071 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 16130
Query: 914 SSNSSI----------SLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVG 963
+N +I +L W + P + E + K+ + TC V
Sbjct: 16131 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDN-------KEPVLYDTHVNKLVVDDTCTLVI 16183
Query: 964 GLIERQKY-FFRIRAVNEAGVGEPVELDKGVRAMP-PPAAPKFDLSARLKSHMVVRAGTA 1021
R + I AVN G E+ V P PP P + +S + +
Sbjct: 16184 PQSRRSDTGLYTITAVNNLGTASK-EMRLNVLGRPGPPVGP-----IKFESVSADQMTLS 16237
Query: 1022 LCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEF 1081
GS + + +K K ++ + I V+RI+ QN++
Sbjct: 16238 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKY 16297
Query: 1082 G-----EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRD 1136
G ++ + + P P + N++T+ W Y + +D
Sbjct: 16298 GIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKD 16357
Query: 1137 ASTATWYTA-----AERVFSNKYTVTGLLPGRKYYFRVVARNEIG------DSEPLDSRD 1185
++ W Y VTGL+ G Y FRV A N G S+P +RD
Sbjct: 16358 TTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARD 16417
Score = 182 bits (463), Expect = 1e-45
Identities = 168/649 (25%), Positives = 276/649 (42%), Gaps = 83/649 (12%)
Query: 582 KYTFRAKGTESEASVFIADPPTIDPSV------------LEALAAHAITVKVGHTAHIKV 629
+Y FR SE + +P T+ SV L+A + ++ T + V
Sbjct: 25073 EYNFRICAINSEG---VGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFV 25129
Query: 630 PFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA 689
+G+P P+V W K +T+ R +E +L I N R DSG L L+N+ GS
Sbjct: 25130 TIKGRPEPEVKWEKAEGILTD--RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSK 25187
Query: 690 TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
TA +++ VLD P P + E+ V + W+ P +GG +T +IVE+R +K++
Sbjct: 25188 TAFVNVRVLDSPSAPVN-LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 25246
Query: 750 KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQP 808
I K T F ++EG +Y FR+LA N G+ P ET E V P PPG +
Sbjct: 25247 TITNNCTKTT-FRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVT-- 25303
Query: 809 QVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
+ DVT+ TI W P DGG+ + GY+VE + KGS W + ++ + T+ GL
Sbjct: 25304 -LVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTA 25360
Query: 869 DTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE 928
EY FRV AVN+ G P V+A+D P + H + ++ RE +
Sbjct: 25361 GEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH-------TFNVKAREQLK 25413
Query: 929 GDPPSGYILEMRAEDTKEWSK-------CTKIPISG----TCYTVGGLIERQKYFFRIRA 977
D P + R + T W K T++ +S T ++ + + +
Sbjct: 25414 IDVP----FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV 25469
Query: 978 VNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP--- 1033
N AG + P+ + V P P P +R C S +PP
Sbjct: 25470 SNSAGSITVPITII--VLDRPGPPGP-------------IRIDEVSCDSITISWNPPEYD 25514
Query: 1034 -----PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY-D 1087
+ I +K + ++++ + I +R+ +N +G++ Y +
Sbjct: 25515 GGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE 25574
Query: 1088 IHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWY 1143
VA++ P PP ++ +T+ +TW + Y + ++ S+ W
Sbjct: 25575 SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWS 25634
Query: 1144 TAAERVFSN-KYTVTGLLPGRKYYFRVVARNEIG------DSEPLDSRD 1185
A + + ++ + V+GL G Y +RV A N G EP+ +RD
Sbjct: 25635 KANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARD 25683
Score = 180 bits (457), Expect = 7e-45
Identities = 254/1094 (23%), Positives = 428/1094 (39%), Gaps = 120/1094 (10%)
Query: 269 IKGTEPLRIQY--------SLGKYDVKQMGTKYMLVISNVNMNDAGIY----SLSVGDKR 316
+ GT P+ I++ S V + T L + D+G Y S VG
Sbjct: 4791 VGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTAT 4850
Query: 317 MSAELTVLDEPLKFLGEMKPVKVTER-QTAVFEIRLSKKEPNFV-WKFNGKELKRDDKYE 374
A L V EP +F+ + PV V Q+ FE +++ V W +G E+ K+
Sbjct: 4851 SKATLFV-KEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHG 4909
Query: 375 ITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTID---RIPIKFVSNLKNVRVK 431
I+ DGL T +I AR+ +SG + EA N A +I+ + P F+ LK V V
Sbjct: 4910 ISFI-DGLA-TFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVV 4967
Query: 432 ERSRACLECELT-SKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTV 490
+ S LECE+T + + W K+ + + KY++ L I SD GEY
Sbjct: 4968 KYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQC 5027
Query: 491 VAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDG 550
+ +G + V ++E + +K + S V + WLKD
Sbjct: 5028 IVSNEGGSCS--CSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDD 5085
Query: 551 KEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAK---GTESEASVFIADPPTIDPS 607
+ + + + I +V L S+ H G+YT +AK G E + + P
Sbjct: 5086 QILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPA---Q 5142
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
++E + +T K T V G P KV W KDG ++ SM + A I
Sbjct: 5143 IVEKAKSVDVTEKDPMTLECVVA--GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRI 5200
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELS---GSCVHMKWKA 724
+ +++DSG K++ND GS++ +L VLD+ PP + ++ GS +HM+ K
Sbjct: 5201 QSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKV 5260
Query: 725 PKDNGGRPVT-QFIVERRAVGKKSWIKIGEVDGKVTNFSTN-KVEEGKAYQFRILAVNSE 782
+G P++ Q+ + + + + ++ + V+ N ++E+ Y ++ V +
Sbjct: 5261 ---SGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGD 5317
Query: 783 GVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRK 842
+ T + EPP F +P ++ T+ + A I++
Sbjct: 5318 DACSGILTVK-------EPPSFLVKPGRQQAIPDS-TVEFKA------------ILKGTP 5357
Query: 843 KGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDP--- 899
W + + + G KC + LE + + +V+ + GQ + ++ V D
Sbjct: 5358 PFKIKWFKDDVELVSGPKCFIG--LEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTT 5415
Query: 900 ----VKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYIL-----EMRAEDTKEWSKC 950
+PP V+ L S + S G P + E+ A D +
Sbjct: 5416 MLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFI 5475
Query: 951 TKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKF-DLSAR 1009
+ + + L F A N AG V PP F +
Sbjct: 5476 DSVAV----IQMNNLSTEDSGDFICEAQNPAG---STSCSTKVIVKEPPVFSSFPPIVET 5528
Query: 1010 LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKD--GVPTKGRETITKSKNHSQFLINSTKR 1067
LK+ + + SG+PP +V+W KD + + + I H+ I +
Sbjct: 5529 LKN-------AEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDT 5581
Query: 1068 SDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE 1127
SD G Y QNE G V++ + PR F N++T+ ++Q E
Sbjct: 5582 SDIGEYHCKAQNEVGSDTCVCTVKLKEPPR-------FVSKLNSLTVVAGEPAELQASIE 5634
Query: 1128 AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD-- 1185
I W E V + R + VA + +EP ++
Sbjct: 5635 GAQPIF------VQWLKEKEEVIRESENI------RITFVENVATLQFAKAEPANAGKYI 5682
Query: 1186 TWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVT 1245
+ N +++ A L E V P TV G+ CT+ C G P +V
Sbjct: 5683 CQIKNDGGMRENMATLMVLE------PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVE 5736
Query: 1246 LYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
YK +T++ K ++ + + +L I + +D+G Y+ V+N +GK SSCT V D
Sbjct: 5737 WYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGK--SSCT-AVVDV 5793
Query: 1306 DDKSVVASITESLQ 1319
D++V S T L+
Sbjct: 5794 SDRAVPPSFTRRLK 5807
Score = 176 bits (447), Expect = 1e-43
Identities = 152/630 (24%), Positives = 264/630 (41%), Gaps = 70/630 (11%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ + E ++ + + WK P D+GG +T + VERR W++ +
Sbjct: 20572 PGPPE-KPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLR 20630
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVTKEAVT 819
++EG Y+FR+ A N G+ P E ++ V + PPG S P VTD TK++ +
Sbjct: 20631 CKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSAS 20690
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVP-VNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
+ W P DGG + GY+VE +K G W+ ++ T+ V L +Y FR+ A
Sbjct: 20691 LAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 20750
Query: 879 VNKAGPGQPSV-PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPP----- 932
+N AG G+P+V P +V ++ L +L + + +S+ P +G P
Sbjct: 20751 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTW 20810
Query: 933 --SGYILEMRA--EDTKEWS-----KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV 983
L+ RA E+T+ ++ +C + T+ ++ F +R ++ G
Sbjct: 20811 TKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 20870
Query: 984 G---EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK 1040
P ++ K + P D +R+ +++V +K
Sbjct: 20871 VLNLRPTDITKDSVTLHWDL-PLIDGGSRITNYIV-----------------------EK 20906
Query: 1041 DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPR 1097
K T T + + + +R++ +NE+G V+ ++ P
Sbjct: 20907 REATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS 20966
Query: 1098 PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKY 1154
PP +L + + +TV+L W P + DG + Y+I + + W T V +
Sbjct: 20967 PPDSLNIMDITKSTVSLAW---PKPKHDGGSKITGYVIEAQRKGSDQW-THITTVKGLEC 21022
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPR 1214
V L G +Y F+V+A N G S P +SR + + + +L + Y+K A
Sbjct: 21023 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLR-GIYQKLVIAKA-- 21079
Query: 1215 FVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPT 1274
G + + LG P+PTVT KGD + + + +T+ L I
Sbjct: 21080 ------------GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINE 21127
Query: 1275 CTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
C DSG Y + N +G+ T+ V+D
Sbjct: 21128 CVRSDSGPYPLTARNIVGEVGDVITIQVHD 21157
Score = 174 bits (442), Expect = 4e-43
Identities = 163/600 (27%), Positives = 259/600 (43%), Gaps = 61/600 (10%)
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L+A + ++ G T + VP +G+P PK+TW K + + + + ++ + L
Sbjct: 19695 LDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCE 19754
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
N + D+G +L L+N G T+ + VLD P PP V E+S ++ W+ P +
Sbjct: 19755 NVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVN-VTVKEISKDSAYVTWEPPIID 19813
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG P+ ++V++R +KSW + K T+F +EEGK+Y FR+ A N G+ DP
Sbjct: 19814 GGSPIINYVVQKRDAERKSWSTVTTECSK-TSFRVANLEEGKSYFFRVFAENEYGIGDPG 19872
Query: 789 ETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW 848
ET + + + PG +V V+K + +I W P DGG+ ++GY+V+ + N W
Sbjct: 19873 ETRDAVKAS--QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTE-ENKW 19929
Query: 849 VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL--- 905
V K + + L E EY FRV A N+ G G PS +VVA+D V P L
Sbjct: 19930 QRVMKS--LSLQYSAKDLTEGKEYTFRVSAENENGEGTPS--EITVVARDDVVAPDLDLK 19985
Query: 906 -VQDLHVSDSSNSSISLAWREPAEGDP-PSGYILEMRAEDTKEWSKCTKIPIS--GTCYT 961
+ DL NS+ L + P +G P PS + + ED + S T
Sbjct: 19986 GLPDLCYLAKENSNFRL--KIPIKGKPAPS--VSWKKGEDPLATDTRVSVESSAVNTTLI 20041
Query: 962 VGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAP-KFDLSARLKSHMVVRAGT 1020
V + + I N AG E K V P P KFD + A T
Sbjct: 20042 VYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFD-------EVTAEAMT 20094
Query: 1021 ALCIHAAFSGSPPPD---------VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSG 1071
+PP D ++ ++D V K T + + F +
Sbjct: 20095 -------LKWAPPKDDGGSEITNYILEKRDSVNNKW-VTCASAVQKTTFRVTRLHEGMEY 20146
Query: 1072 VYRILLQNEFG----------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+R+ +N++G AR+ V D P PP + + ++V+LTW
Sbjct: 20147 TFRVSAENKYGVGEGLKSEPIVARHPFD--VPDAPPPP---NIVDVRHDSVSLTWTDPKK 20201
Query: 1122 VQEDGEAHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
Y + ++ ++ W A + + + VTGL G +Y FRV+A N G +P
Sbjct: 20202 TGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKP 20261
Score = 174 bits (440), Expect = 7e-43
Identities = 143/479 (29%), Positives = 208/479 (43%), Gaps = 77/479 (16%)
Query: 743 VGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPP 802
V KKS + I VD K ++ T +E AVN G V N ++ P
Sbjct: 13742 VPKKSTVTI--VDSKRSDTGTYIIE----------AVNVCG-----RATAVVEVNVLDKP 13784
Query: 803 GFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCT 862
G + +TDVT E+ +TWN P DGG+ + Y+VERR S +W ++ ++ T
Sbjct: 13785 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSST-VKDTNFK 13843
Query: 863 VDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
L+ + EY FRV A N G G+P V +S + AK PPG L SD + +++L
Sbjct: 13844 ATKLIPNKEYIFRVAAENMYGVGEP-VQASPITAKYQFDPPGPPTRLEPSDITKDAVTLT 13902
Query: 923 WREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNE 980
W EP + G P +GY +E DT +W +C K+P+ T Y V GL ++KY FR+ A N
Sbjct: 13903 WCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENL 13962
Query: 981 AGVG------EPVELDKGVRAMPPPAAP-----------------KFDLSARLKSHMV-- 1015
AG G EP+ + + PP P + D A+++S+++
Sbjct: 13963 AGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEM 14022
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
++ GT + A +GVPT +Q L+ +R+
Sbjct: 14023 LKTGTDEWVRVA-------------EGVPT------------TQHLLPGLMEGQEYSFRV 14057
Query: 1076 LLQNEFGEARYD-----IHVRVADFP-RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH 1129
N+ GE+ + R +P PP L + NT L W +
Sbjct: 14058 RAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITN 14117
Query: 1130 YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWL 1188
YI+ KRD W T V K TVT L G Y FRV A N IG S+ + D+ L
Sbjct: 14118 YIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVL 14176
Score = 174 bits (440), Expect = 7e-43
Identities = 141/466 (30%), Positives = 208/466 (44%), Gaps = 32/466 (6%)
Query: 730 GRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFST-------NKVEEGKAYQFRILAVNSE 782
GRP + + V + +IG +D K T+F T NK + GK + + NS
Sbjct: 19719 GRPPPKITWSKPNVNLRD--RIG-LDIKSTDFDTFLRCENVNKYDAGK---YILTLENSC 19772
Query: 783 GVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRK 842
G + E ++ PG V +++K++ +TW P DGG+P++ Y+V++R
Sbjct: 19773 G-----KKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRD 19827
Query: 843 KGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKP 902
W V + T V L E Y FRV A N+ G G P +V A +
Sbjct: 19828 AERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKAS---QT 19883
Query: 903 PGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCY 960
PG V DL V S SS S+ W++P G GY+++ E+ K W + K Y
Sbjct: 19884 PGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKS--LSLQY 19940
Query: 961 TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGT 1020
+ L E ++Y FR+ A NE G G P E+ V A AP DL + + +
Sbjct: 19941 SAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENS 19998
Query: 1021 ALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
+ G P P V W+K D + T R ++ S ++ ++ ++SD+G Y I L+
Sbjct: 19999 NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLK 20058
Query: 1079 NEFGEARYDIHVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDA 1137
N G I ++V P PT F+EV +TL W D +YI+ KRD+
Sbjct: 20059 NVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 20118
Query: 1138 STATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
W T A V + VT L G +Y FRV A N+ G E L S
Sbjct: 20119 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKS 20164
Score = 172 bits (437), Expect = 1e-42
Identities = 175/656 (26%), Positives = 265/656 (40%), Gaps = 95/656 (14%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG-----EVD 755
P PP G+ + L + + + W P DNGG P+T + +E+R G W ++ +V
Sbjct: 15599 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 15657
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVT 814
K F+ ++ EG YQFR +A+N+ G+ P E ++ AG+PI PPG S P+V D T
Sbjct: 15658 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKT 15717
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLLEDTEY 872
K ++++ W P +DGG+P+ GYIVE +++G+ W VN+ I +C V L E +Y
Sbjct: 15718 KSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKY 15777
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA----E 928
FRV AVN+AG +PS + + A D + P + D+ D R PA
Sbjct: 15778 RFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGR 15837
Query: 929 GDPPSGYILEMRAE----------------DTKEWSKCTKIPISGTCYTVGGLIERQKYF 972
P S + + +A+ +T E S IP +T KY
Sbjct: 15838 PTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT-------GKY- 15889
Query: 973 FRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC--IHAAFSG 1030
I A N+AG + V+ M P PK LK + R L + G
Sbjct: 15890 -SITAKNKAG---QKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDDDGG 15940
Query: 1031 SPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG-------- 1082
+ +K + K + + F++ +R+ +N FG
Sbjct: 15941 DRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETI 16000
Query: 1083 ---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM-----K 1134
AR I+ P PP L++ NTV L+W + HYI+
Sbjct: 16001 QRTTARDPIYP-----PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDP 16055
Query: 1135 RDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQ 1193
W +R V ++TV L+ G +Y FRV A N G S+P
Sbjct: 16056 TGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP------------- 16102
Query: 1194 IQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNI 1253
SA + P + + P + + V G + + G P PT+T +K
Sbjct: 16103 ----SATVGPCDCQR-PDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKK 16157
Query: 1254 TANSKFWYNST-------SGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
N + T CTLVIP D+G Y++ N LG L V
Sbjct: 16158 PDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 16213
Score = 172 bits (437), Expect = 1e-42
Identities = 178/792 (22%), Positives = 321/792 (40%), Gaps = 74/792 (9%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFI------A 599
W+K +E+++ ++I L G Y +AK E SV +
Sbjct: 22577 WIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDR 22636
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
P P V+ + A T+ K P + + + + E + ++
Sbjct: 22637 PGPPEGPVVISGVTAEKCTLAW------KPPLQDGGSDIINYIVERRETSRLVWTVVDAN 22690
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHG--------SATATLHLSVLDRPKPPQGRVEFL 711
++ + + + N +G A V D PK P E
Sbjct: 22691 VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP----EVT 22746
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK-----IGEVDGKVTNFSTNKV 766
++ + + W+ P +GG + +++E+R W + IGE+ +VT N
Sbjct: 22747 TVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH- 22805
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
Y+FR+ A N+ G+S+P A +PI PG + P+V D+T+ +V ++W+ P
Sbjct: 22806 ----DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKP 22861
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLEDTEYEFRVIAVNKAGP 884
DGG + GYIVE+ W I T V+ LLE EY FR+ A+NKAG
Sbjct: 22862 IYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGV 22921
Query: 885 GQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN--SSISLAWREPAEGDPPSGYILEMRAE 942
G+ + ++ ++ ++ P + DL + N + SL P +G P + + + +
Sbjct: 22922 GEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRP-TPEVKWGKVD 22980
Query: 943 DTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAP 1002
+ + S T + + + + N +G VR + P+ P
Sbjct: 22981 GEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVT---VRVLDTPSPP 23037
Query: 1003 KFDLSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
LK + + ++ GS + I +K K + + + + +
Sbjct: 23038 -----VNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSW 23092
Query: 1061 LINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWN 1117
I+ + S +R+ +NE+G A+ ++VA+ P+PP + + + N+V+L+W
Sbjct: 23093 KIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWT 23152
Query: 1118 HSPDVQEDGEAHYI--IMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEI 1175
+ DG + I I++ A + ++ RV S + +T L G +Y FRVVA NE
Sbjct: 23153 KP---EHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEK 23209
Query: 1176 GDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCA 1235
G S+P S ++ KD + + K P F + ++V GQD +
Sbjct: 23210 GRSDPR-SLAVPIVAKDLVIEPDVK------------PAFSS----YSVQVGQDLKIEVP 23252
Query: 1236 FLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDR 1295
G P+PT+T K + + ++ + + TL I D G Y + V N +G+
Sbjct: 23253 ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKT 23312
Query: 1296 SSCTLTVYDKDD 1307
+S + DK D
Sbjct: 23313 ASIEIVTLDKPD 23324
Score = 171 bits (432), Expect = 6e-42
Identities = 170/661 (25%), Positives = 275/661 (41%), Gaps = 101/661 (15%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP + ++++ V +KW+ PK++GGRP+ ++++E++ W+K G+ G N
Sbjct: 14184 PGPPYA-LAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 14242
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFA-GNPIEPPGFASQPQVTDVTKEAVT 819
F V EG QF++ A N GV P E E+ + +P PP VTD ++ +
Sbjct: 14243 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 14302
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVD-GLLEDTEYEFRVIA 878
I W P ++GG+P++GY VE G+ W+ VN PI+ K V+ G++ D EY RV A
Sbjct: 14303 IAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRA 14362
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGL---VQDLHVSDSSNSSISLAWREPAEGDPPSGY 935
VN G +PS S +VVAKDP P + D+ V + SI + +R A P +
Sbjct: 14363 VNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFR--AVPVPTVSW 14420
Query: 936 ILEMRAEDTKEWSKCTKIPISGTCYT----VGGLIERQKYFFRIRAVNEAGVGEPVELDK 991
+D KE ++ + + V + + I N+ G ++
Sbjct: 14421 -----HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG-SATASINV 14474
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA-FSGSPP--PDVIWQKDGVPTKGR 1048
V +P P +K+ + ++ L F G P V+ +++ GR
Sbjct: 14475 KVIGLPGPCKD-------IKASDITKSSCKLTWEPPEFDGGTPILHYVLERREA----GR 14523
Query: 1049 ET---ITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR---VADFPR----P 1098
T + +N + + + +R+ N+ G Y I ++ +A P+ P
Sbjct: 14524 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY-IELKNPVIAQDPKQPPDP 14582
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSN-KYT 1155
P ++ + +T+TW P + + G YII K W E + YT
Sbjct: 14583 PVDVEVHNPTAEAMTITWK--PPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYT 14640
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
GL G++Y FRV A N G SEP S P + D AP+
Sbjct: 14641 AKGLEEGKEYQFRVRAENAAGISEP-----------------SRATPPTKAVDPIDAPKV 14683
Query: 1216 V--TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWY------------ 1261
+ T L+ V RG + + + G+P PT+T K D N+ +
Sbjct: 14684 ILRTSLE---VKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE 14739
Query: 1262 ------------------NSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVY 1303
NS G L + D G Y + VEN+ G ++ CT++V
Sbjct: 14740 VQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 14799
Query: 1304 D 1304
D
Sbjct: 14800 D 14800
Score = 169 bits (427), Expect = 2e-41
Identities = 217/939 (23%), Positives = 367/939 (39%), Gaps = 112/939 (11%)
Query: 430 VKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
VK R + ++ + T+ W+KDGQ L T+ +++ L I++A D G Y
Sbjct: 25406 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 25465
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLA---TVKSGMSDVHAATGSPAEL---CVVLNDEKV 542
+ T IV + D + +P E C + N
Sbjct: 25466 ELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISN---- 25521
Query: 543 EGVWLKDGKEITDLPGMQIVKQGAVH---KLIFPSMGPEHEGKYTFR---AKGTESEASV 596
++ + KE T IV Q K++ + G E++ + K + SE+S
Sbjct: 25522 ---YIVEKKETTSTT-WHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSA 25577
Query: 597 FIADPPTIDPS------VLEA-----LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+A+ P P V+ A L + V G + I K + W K
Sbjct: 25578 VVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKAN 25637
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
+ + ++ + G D+ L+ E+ I G + + P P
Sbjct: 25638 KILIADTQMKVS-GLDEGLMYEYRVYAENIAGI--------GKCSKSCEPVPARDPCDPP 25688
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNK 765
G+ E ++ V +KW P +GG +T +IVERR + W+K + + T F +
Sbjct: 25689 GQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTE 25748
Query: 766 VEEGKAYQFRILAVNS-EGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDV--TKEAVTIT 821
+ E + Y+FR+ A N+ + VS+P E T + + +EPP + DV K +
Sbjct: 25749 LTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLK 25808
Query: 822 WNAPTQDGGAPVLGYI---VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
NA PV+ + +E ++ + + + K D + DT + +
Sbjct: 25809 INADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVK---DCIRRDTG---QYVL 25862
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYI 936
K G SV + V P P G L ++ + SL+W P E G YI
Sbjct: 25863 TLKNVAGTRSVAVNCKVLDKPGPPAG---PLEINGLTAEKCSLSWGRPQEDGGADIDYYI 25919
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
+E R W+ C + T V L++ +Y FR+ VN+ GVGEP+E ++A+
Sbjct: 25920 VEKRETSHLAWTICEG-ELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLE-SVAIKAL 25977
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT---- 1052
P P S + S V + LC P D + G + RE +
Sbjct: 25978 DPFTVPSPPTSLEITS--VTKESMTLCW-----SRPESDGGSEISGYIIERREKNSLRWV 26030
Query: 1053 --KSKNHSQFLINST--KRSDSGVYRILLQNEFG---EARYDIHVRVAD---FPRPPTNL 1102
K + ST + YR+ +N G + +R D P PP+
Sbjct: 26031 RVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKP 26090
Query: 1103 RLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYTVTGL 1159
++ + T+T+ W DG A Y + + + W T+ + + +YT++GL
Sbjct: 26091 KIVDSGKTTITIAWVKP---LFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGL 26147
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSRDTWLI---NKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
G +Y FRV + N++G S+P DS D + ++ + D+ ++++
Sbjct: 26148 TTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMR-------------- 26193
Query: 1217 TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
K V G TMT F G P P V K D ++ ++ + ++T +L I
Sbjct: 26194 ---KTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL--RTRAYVDTTDSRTSLTIENAN 26248
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASIT 1315
DSG Y++ ++N L +S TL V D +IT
Sbjct: 26249 RNDSGKYTLTIQNVL--SAASLTLVVKVLDTPGPPTNIT 26285
Score = 167 bits (424), Expect = 5e-41
Identities = 248/1114 (22%), Positives = 419/1114 (37%), Gaps = 162/1114 (14%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRM 317
P K+ W K LR + L D+K L NVN DAG Y L S G K
Sbjct: 19721 PPPKITWSKPNVNLRDRIGL---DIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEY 19777
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEP---------NFVWKFNGKELK 368
+ + VLD P PV VT ++ + ++ + P N+V + E K
Sbjct: 19778 TIVVKVLDTP------GPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERK 19831
Query: 369 R---------DDKYEITVSEDGLTHTLKI---KDARLSDSGEFSAEAGNLVQKAQLTIDR 416
+ + E+G ++ ++ + + D GE + +A Q +D
Sbjct: 19832 SWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGE-TRDAVKASQTPGPVVD- 19889
Query: 417 IPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKK---DGQLLMHGTKYSMNHEGKRA 473
+K RS + C ++ WKK DG + G E +
Sbjct: 19890 -------------LKVRSVSKSSC-------SIGWKKPHSDGGSRIIGYVVDFLTEENKW 19929
Query: 474 ELIIEDAQL-------SDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKS----GMSD 522
+ +++ L ++G EYT + + E + I V G+ D
Sbjct: 19930 QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPD 19989
Query: 523 VH--AATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHK-LIFPSMGPEH 579
+ A S L + + + V K G++ V+ AV+ LI
Sbjct: 19990 LCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSD 20049
Query: 580 EGKYTFRAKGT----ESEASVFIADPPTID--PSVLEALAAHAITVKVGHTAHIKVPFRG 633
GKYT K E S+ + P I P + + A A+T+K P +
Sbjct: 20050 AGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWA-------PPKD 20102
Query: 634 KPLPKVTWY-KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA--- 689
++T Y + + + V+ + ++ + +N +G
Sbjct: 20103 DGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGL 20162
Query: 690 -----TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVG 744
A V D P PP +++ V + W PK GG P+T + +E +
Sbjct: 20163 KSEPIVARHPFDVPDAPPPPN----IVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 20218
Query: 745 KKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP-LETEEVFAGNPIEPPG 803
W + + ++ +F + EG Y+FR++A+N GV P L +E V A +PI+PPG
Sbjct: 20219 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 20278
Query: 804 FASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTV 863
+P+V ++T+ +VT+ W P DGG + GYIVE+R S W+ N + TV
Sbjct: 20279 ---KPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTV 20335
Query: 864 DGLLEDTEYEFRVIAVNKAGP-GQPSVPSSSVVAKDPVKPPGLVQDLHVSD-----SSNS 917
L+E +YEFR+ A N AG PS + +++ KD + P +V D + D + ++
Sbjct: 20336 TDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDT 20395
Query: 918 SISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRA 977
+ A + P S + + + ++ T P S + T+ + + I A
Sbjct: 20396 IVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKDAGEYTITA 20454
Query: 978 VNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
N G E V++ V +P P P + + +A GSP
Sbjct: 20455 TNPFGTKVEHVKVT--VLDVPGPPGP-----VEISNVSAEKATLTWTPPLEDGGSPIKSY 20507
Query: 1037 IWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR--YDIHVRVAD 1094
I +K +++ + + + + ++R+ N +G+ V++ D
Sbjct: 20508 ILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVD 20567
Query: 1095 F---PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFS 1151
P PP + NT T++W D Y + +R+ + W A + S
Sbjct: 20568 RFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS 20627
Query: 1152 N-KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWR 1210
+ + VTGL G Y FRV A N G P ++ D+ L+ KD
Sbjct: 20628 DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLM-----------------KDAA 20670
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNIT--------ANSKFWYN 1262
+ P P PH D T A L +P Y G + IT + W
Sbjct: 20671 YPPG--PPSNPHVT----DTTKKSASLAWGKPH---YDGGLEITGYVVEHQKVGDEAWIK 20721
Query: 1263 STSG----VCTLVIPTCTLKDSGDYSVLVENELG 1292
T+G + V+P K+ ++ + N+ G
Sbjct: 20722 DTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 20755
Score = 167 bits (423), Expect = 6e-41
Identities = 166/658 (25%), Positives = 277/658 (42%), Gaps = 63/658 (9%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
+++GA +KL ++ EG T +E +PP ++ L+ I +
Sbjct: 15066 IREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQ----EPPAVE---LDVSVKGGIQIMA 15118
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
G T I G+P+P W K+ E+ +++RV ++ ++ L I + +R+D G ++
Sbjct: 15119 GKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVIDNVGTKSELIIKDALRKDHGRYVIT 15177
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
N GS A + V D P P + C+ + W P+D+GG +T FI+ER+
Sbjct: 15178 ATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCL-LNWSDPEDDGGSEITGFIIERK 15236
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
+W + ++ + + + EG+ Y+FR++A N G P+E + A +P+ P
Sbjct: 15237 DAKMHTWRQ--PIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGP 15294
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
P + T+ TK +T+ W P +GG+P+ GYI+E+R+ + VNK T
Sbjct: 15295 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 15354
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
V+ L E YEFRV AVN+ G +PS+P + V+ D V PP + L V +I +
Sbjct: 15355 LVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEV-PPTIKLRLSV---RGDTIKV 15410
Query: 922 AWREPAEGDPPSGYILEMRAEDTKEWSK-------------CTKIPIS----GTCYTVGG 964
EP P L M EWSK TK +S T ++
Sbjct: 15411 KAGEPVH-IPADVTGLPM---PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPK 15466
Query: 965 LIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSAR---LKSHMVVRAGT 1020
+ K + + A N G V V ++ R PP D+ A L + G
Sbjct: 15467 AVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGG 15526
Query: 1021 ALCIHAAFSGSPPPDVIWQKDGVPTKGR-ETITKSKNHSQFLINSTKRSDSGVYRILLQN 1079
+ H VI ++D K E +T + ++ I + +R+ N
Sbjct: 15527 SEITHY---------VIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVN 15577
Query: 1080 EFG---EARYDIHVRVAD---FPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM 1133
++G E + D V + D P PP ++ ++ ++W D Y +
Sbjct: 15578 KYGISDECKSD-KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLE 15636
Query: 1134 KRDASTATWYTAAERVFSN------KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
KR+ + W + + ++ V LL G KY FR +A N G P + D
Sbjct: 15637 KREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSD 15694
Score = 165 bits (417), Expect = 3e-40
Identities = 163/635 (25%), Positives = 271/635 (42%), Gaps = 78/635 (12%)
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
+D +PP+ V ++S + V + W+ P +GG +T +IVERR + W K +
Sbjct: 26765 IDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 26823
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEG-------VSDPLETEEVFAGNPIEPPGFASQPQV 810
T F + + + Y+FR+ A N+ G V P+ + + G I+ P +
Sbjct: 26824 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLP-----LEY 26878
Query: 811 TDVTK--EAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
T+V K ++ A AP + + + ++ +N V V + T L++
Sbjct: 26879 TEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCV-----ENTTDLASILIK 26933
Query: 869 DTE------YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
D + YE ++ N G ++ V D PPG + + I+L
Sbjct: 26934 DADRLNSGCYELKLR--NAMGSASATI---RVQILDKPGPPG--GPIEFKTVTAEKITLL 26986
Query: 923 WREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNE 980
WR PA+ G + YI+E R WS ++ + T +I+ +Y FR+RAVN+
Sbjct: 26987 WRPPADDGGAKITHYIVEKRETSRVVWSMVSE-HLEECIITTTKIIKGNEYIFRVRAVNK 27045
Query: 981 AGVGEPVELDKGV--RAMPPPAAPKF-DLSARLKSHMVVRAGTALCIHAAFSGSPPPDVI 1037
G+GEP+E D V A P P +++ K+ M V + A GS
Sbjct: 27046 YGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPI----ADGGSDISGYF 27101
Query: 1038 WQKDGVPTKGRETITKS--KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV--- 1092
+K + G + K ++ Q + T+ SD YR+ N G+ +
Sbjct: 27102 LEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKA 27160
Query: 1093 ---ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAE 1147
D P PP +R+ + +++TL W S V + G A Y++ R W T +
Sbjct: 27161 ADPIDPPGPPAKIRIADSTKSSITLGW--SKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 27218
Query: 1148 R--VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYE 1205
+ V + +Y V+ L PG YYFRV A N G EP++ + P +
Sbjct: 27219 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNE-----------------PVQ 27261
Query: 1206 KKDWRHAPRFVTPLKPHTVL---RGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
KD AP + T + G+D + F G P PTVT K + N+ +++++
Sbjct: 27262 AKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE 27321
Query: 1263 STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSS 1297
+T L IP T D+G Y + +EN +G+ +SS
Sbjct: 27322 NTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSS 27356
Score = 165 bits (417), Expect = 3e-40
Identities = 205/927 (22%), Positives = 345/927 (37%), Gaps = 119/927 (12%)
Query: 441 ELTSKDVTLRWK---KDGQLLMHGTKYSMN-HEGKRAELIIEDAQLSDGGEYTVVAMQDG 496
++T + +TL+W +DG + G YS+ +G + +S+ +YTV + G
Sbjct: 27865 DVTRETITLKWNPPLRDGGSKIVG--YSIEKRQGNERWVRCNFTDVSEC-QYTVTGLSPG 27921
Query: 497 D----------------PTEYYSTAIVTVEERLATV----KSGMSDVHAATGSPAELCVV 536
D P S I+T +E + + + +G + +
Sbjct: 27922 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 27981
Query: 537 LNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT----E 591
+ V V W KDG EI M+I L +H G YT AK +
Sbjct: 27982 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 28041
Query: 592 SEASVFIADPP--TIDPSVLEALAAHAITV------KVGHTAHIKVPFRGKPLPKVTW-- 641
+E V + D P + P + +T+ G + ++ W
Sbjct: 28042 AEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWAL 28101
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP 701
+D E + + G + +S + G L D A + +V D P
Sbjct: 28102 IEDKCEAQSYTAIKLINGNEYQF-RVSAVNKFGVGRPL-----DSDPVVAQIQYTVPDAP 28155
Query: 702 KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK-IGEVDGKVTN 760
P+ ++G+ + + W P+ +GG + Q+I+ERR W+K I + T
Sbjct: 28156 GIPEPS----NITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETR 28211
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVT 819
F + EG Y+F ++A N+ GV + P+ PPG + +VTD +K V+
Sbjct: 28212 FKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVS 28271
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAV 879
+ W+ P DGG ++GYI+E K W VN + T+ TV L EY+FRV A+
Sbjct: 28272 LEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAI 28331
Query: 880 NKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDS----SNSSISL------------AW 923
N AG G + ++ A D + P L D + + + +SI L W
Sbjct: 28332 NGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVW 28391
Query: 924 REPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV 983
+P I + T C + TV + F ++ ++ G
Sbjct: 28392 SKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP 28451
Query: 984 GEPVELDKGVRAMPPPA--APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKD 1041
P+ R AP D AR+ ++V +K
Sbjct: 28452 PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVV-----------------------EKR 28488
Query: 1042 GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR-YDIH--VRVADFPRP 1098
+ + I++ F +N +R+ NE+G Y++ + + P P
Sbjct: 28489 EASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP 28548
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYT 1155
P L + + ++ L W PD DG + Y++ R + W A +T
Sbjct: 28549 PRRLDVVDTSKSSAVLAWL-KPD--HDGGSRITGYLLEMRQKGSDFWVEAGHTK-QLTFT 28604
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
V L+ +Y FRV A+N+ G SEP ++ + +I + QI+ +A L
Sbjct: 28605 VERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP-TADLTGITN--------- 28654
Query: 1216 VTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
+ T G T+ G P P VT ++ + + +T TL +
Sbjct: 28655 ----QLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 28710
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTV 1302
DSG Y + +EN G S T+ V
Sbjct: 28711 MRGDSGRYFLTLENTAGVKTFSVTVVV 28737
Score = 164 bits (416), Expect = 4e-40
Identities = 230/1109 (20%), Positives = 416/1109 (37%), Gaps = 125/1109 (11%)
Query: 268 WIKGTEPLRIQYSLGKYDVKQMGT------KYMLVISNVNMNDAGIYSL----SVGDKRM 317
++ G P + +++ + + Q T +VI N + G+YSL G+++
Sbjct: 16547 YVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKK 16606
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDK----- 372
+ + VLD P +T + + + + ++ + D +
Sbjct: 16607 TIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPV 16666
Query: 373 -YEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVK 431
Y +T + ++ K + E S G V+ ++ + R PI +++ VK
Sbjct: 16667 TYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVK 16726
Query: 432 ERSRACLECELTSKDVTLRWKKD----GQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGE 487
E +T VTL W G +++ S ++ + D LS +
Sbjct: 16727 E---------VTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSR--K 16775
Query: 488 YTVVAMQDGDPTEYYSTAI--------------VTVEERLA------------TVKSGMS 521
YTV +++GD EY +A+ +T ++ LA T++ G
Sbjct: 16776 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVG-- 16833
Query: 522 DVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEG 581
+ A TG + K + W KD ++ + I A L G
Sbjct: 16834 EAFALTGRYS------GKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSG 16887
Query: 582 KYTFRAKGTES------EASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKP 635
KY + + + +V P + P + + + + K P
Sbjct: 16888 KYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISW------KPPLDDGG 16941
Query: 636 LPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLH- 694
+ + EV ++ + + + +S + + + +N +G + +
Sbjct: 16942 SKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSD 17001
Query: 695 -LSVLDRPKPPQGRVEFL--ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKI 751
+ DR + P + + E++ + W P D GG+P+T +I+E+R K W ++
Sbjct: 17002 SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARV 17060
Query: 752 GEVD-GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQ 809
+ T F + EG Y+FR+ A N G+ DP ++ VFA +PI P P+
Sbjct: 17061 TKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPE 17120
Query: 810 VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLL 867
D T +V +TW P DGG+ +LGYIVE +K G W N P TK V GL
Sbjct: 17121 AIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLR 17180
Query: 868 EDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA 927
+ Y+FRV+AVN AG P+ V+ KD ++PP L+ D +++ + + R A
Sbjct: 17181 DGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSA 17240
Query: 928 --EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
+G P + D ++ P+ G+ + + + N AG
Sbjct: 17241 IIKGVPFPKVTWKKEDRDAPTKARIDVTPV-GSKLEIRNAAHEDGGIYSLTVENPAG--- 17296
Query: 986 PVELDKGVRAMPPPAAPK-FDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP 1044
+ V + P P+ ++S K + L GS + + ++ V
Sbjct: 17297 SKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPL----DDGGSVITNYVVERRDVA 17352
Query: 1045 TKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY---DIHVRVADF---PRP 1098
+ ++ + + ++R+ +N++G + ++ D P P
Sbjct: 17353 SAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGP 17412
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYT 1155
P +L + V+L WN PD DG + Y++ ++ T W + V + +
Sbjct: 17413 PKDLHHVDVDKTEVSLVWN-KPD--RDGGSPITGYLVEYQEEGTQDWIKF-KTVTNLECV 17468
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
VTGL G+ Y FRV A N +G P D + ++ EK
Sbjct: 17469 VTGLQQGKTYRFRVKAENIVGLGLP---------------DTTIPIECQEKLVPPSVELD 17513
Query: 1216 VTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
V ++ V G G P PT I + + + + L I C
Sbjct: 17514 VKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNC 17573
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
+D+G+Y + V N G + LTV D
Sbjct: 17574 LRRDTGEYQITVSNAAGSKTVAVHLTVLD 17602
Score = 163 bits (412), Expect = 1e-39
Identities = 149/604 (24%), Positives = 259/604 (42%), Gaps = 43/604 (7%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
I + P ID L+ ++ K G + +PF+G+P P VTW KD + + R S+E
Sbjct: 27265 ILEAPEID---LDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE 27321
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGS-ATATLHLSVLDRPKPPQGRVEFLELSGS 716
+ +LLTI R D+G +L ++N G ++T+ + VLD P Q +++ +S
Sbjct: 27322 NTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQ-KLQVKHVSRG 27380
Query: 717 CVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRI 776
V + W P +GG P+ +++E+R K++W + T+F + E + FR+
Sbjct: 27381 TVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSS-TSFKLIDLSEKTPFFFRV 27439
Query: 777 LAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGY 836
LA N G+ +P ET E E P + D TK +V ++W P DGG+ + Y
Sbjct: 27440 LAENEIGIGEPCETTEPV--KAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY 27497
Query: 837 IVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVA 896
+VER+ KG W + + V L E + EFRV A N+ G P V +
Sbjct: 27498 VVERKGKGEQTWSHAGIS--KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP-VTIGPITV 27554
Query: 897 KDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPIS 956
K+ + P ++ +SD + +++ + P + + + + W K +P+
Sbjct: 27555 KELIITP----EVDLSDIPGAQVTVRIGHNVHLELP----YKGKPKPSISWLK-DGLPLK 27605
Query: 957 GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV--RAMP-------PPAAPKFDLS 1007
+ + E + A E G V LD V A+P PP+ PK +
Sbjct: 27606 ESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIR 27665
Query: 1008 -ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTK 1066
+K+ V+ + + G +K + + S + F + +
Sbjct: 27666 FDEIKADSVILSWD---VPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLV 27722
Query: 1067 RSDSGVYRILLQNEFGEAR---YDIHVRVADF--PRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+ +R+ +N +G ++ I V F P PP ++ + ++LTW+
Sbjct: 27723 KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWD--AP 27780
Query: 1122 VQEDGE--AHYIIMKRDASTATWYTA-AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
V + G + + K++ ++ W + +Y TGL+ G Y FRV A N G S
Sbjct: 27781 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 27840
Query: 1179 EPLD 1182
P D
Sbjct: 27841 SPSD 27844
Score = 162 bits (409), Expect = 3e-39
Identities = 153/668 (22%), Positives = 271/668 (40%), Gaps = 55/668 (8%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+F+ + VTA E + AVF + + + W + + + + K H +
Sbjct: 11930 KFLTPLKDVTAKEKESAVFTVELSHD-NIRVKWFKNDQ-RLHTTRSVSMQDEGKTHSITF 11987
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTV---------SLLVTEGQEKMDF------------ 166
+ L+ DD+ + A ++A TV L G EK +
Sbjct: 11988 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 12047
Query: 167 KKMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMK 226
K K P K A+ K+ + IL K K D + + G G K
Sbjct: 12048 VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDKTSG--------K 12099
Query: 227 KKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIW-IKGTEPLRIQYSLGKYD 285
+E I++++PL E T F+ E+ + ++ W +KG L+ +
Sbjct: 12100 LDIEDREIKLVRPLHSVEVMETETARFET--EISEDDIHANWKLKGEALLQTP----DCE 12153
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
+K+ G + LV+ N ++ G + + SA L V + L +K V VT +TA
Sbjct: 12154 IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETA 12213
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
F+ LS ++ W GK+L+ DK + +G HTL ++D +L D+GE A +
Sbjct: 12214 TFDCELSYEDIPVEWYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 12271
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
A L + P++F L++ V+E + A LECE++ ++ ++W K+G ++ KY
Sbjct: 12272 FKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYE 12331
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ +G+ +L+I D D YT D ++ ++ + V ++D+
Sbjct: 12332 IVADGRVRKLVIHDCTPEDIKTYTC------DAKDFKTSCNLNVVPPHVEFLRPLTDLQV 12385
Query: 526 ATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A L+ E + W KDG EI I+ +GAV L+ + E +Y+
Sbjct: 12386 REKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC 12445
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFR-GKPLPKVTWYKD 644
+ + + + + + + ++V T IK+ KP +V WYK
Sbjct: 12446 EVRTARTSGMLTVLEEEAV-------FTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKG 12498
Query: 645 GMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
E+ E R + + +L I N ED+G +L + +H + P
Sbjct: 12499 DEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKP 12558
Query: 705 QGRVEFLE 712
Q +E LE
Sbjct: 12559 Q-NLEILE 12565
Score = 160 bits (406), Expect = 6e-39
Identities = 256/1157 (22%), Positives = 432/1157 (37%), Gaps = 180/1157 (15%)
Query: 242 DKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVN 301
++ KV T+ I++ P K+ W K R + + DV +G+K L I N
Sbjct: 17227 EQHIKVGDTLRLSAIIK-GVPFPKVTWKKED---RDAPTKARIDVTPVGSK--LEIRNAA 17280
Query: 302 MNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMKPVKVTE-RQTAVFEIRLSKKEP 356
D GIYSL+V G K +S ++ VLD+P G + ++V+E R+ + + L+ KEP
Sbjct: 17281 HEDGGIYSLTVENPAGSKTVSVKVLVLDKP----GPPRDLEVSEIRKDSCY---LTWKEP 17333
Query: 357 ---------NFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGE---FSAEAG 404
N+V ++R D S T K A+ + G F A
Sbjct: 17334 LDDGGSVITNYV-------VERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 17386
Query: 405 NLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKK---DGQLLMHG 461
N + PIK + L + ++ +V+L W K DG + G
Sbjct: 17387 NQYGRGPFVETPKPIKALDPL---HPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITG 17443
Query: 462 TKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYY-------------STAIVT 508
EG + + + E V +Q G + +T +
Sbjct: 17444 YLVEYQEEGTQDWIKFKTV---TNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIE 17500
Query: 509 VEERLATVKSGM-----SDVHAATGSPAELCVVLNDEKV-EGVWLKDGKEITDLPGMQIV 562
+E+L + + G+ ++ V W DG EI +
Sbjct: 17501 CQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE 17560
Query: 563 KQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVF-------IADPPTIDPSVLEALAAH 615
L + G+Y +V + PPT ++L+ H
Sbjct: 17561 TDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEH 17620
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDS 675
T + P P + + + + ++ + G + L I + +
Sbjct: 17621 M-------TISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCE 17673
Query: 676 GLILLKLKNDHG-----SATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGG 730
+ ++ +N G +T T+ P PP G+ +++ + + W PK +GG
Sbjct: 17674 YVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPP-GKPVVTDITENAATVSWTLPKSDGG 17732
Query: 731 RPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL-E 789
P+T + +ERR V K W+++ + F + EG Y+FR+ A N G+S P
Sbjct: 17733 SPITGYYMERREVTGK-WVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 17791
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
++ + A PI+PPG P++ D ++E + W P DGG+P+LGY+VE +K G+ W
Sbjct: 17792 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWN 17851
Query: 850 PVNKDP-IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQD 908
+NKD I+ V GL+E EY FR+ A N G G+P + SV+AKD + PP + D
Sbjct: 17852 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 17911
Query: 909 LHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ D + R A ++ R E W+K G ++ R
Sbjct: 17912 VTCRDVITVRVGQTIRILAR--------VKGRPEPDITWTK------------EGKVLVR 17951
Query: 969 QKYFFRIRAVN--EAGVGEPVELDKGVRAMPPPAAPKFDLSARLKS---------HMVVR 1017
+K I+ + E + E V D G K+ +SA+ S +++ R
Sbjct: 17952 EKRVDLIQDLPRVELQIKEAVRADHG----------KYIISAKNSSGHAQGSAIVNVLDR 18001
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT---------KSKNHSQFLINSTKR- 1067
G + + W+ G IT K S + TKR
Sbjct: 18002 PGPCQNLKVTNVTKENCTISWENP--LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRL 18059
Query: 1068 -------SDSGVYRILLQNEFG-----EARYDI-HVRVADFPRPPTNLRLFEEVPNTVTL 1114
++ +R+ +N+ G E + I + D P P NL + ++ V L
Sbjct: 18060 IKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYL 18119
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAE-RVFSNKYTVTGLLPGRKYYFRVVARN 1173
W Y + +R + W + + Y V + + Y FRV +N
Sbjct: 18120 KWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKN 18179
Query: 1174 EIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPH---TVLRGQDC 1230
E G+S+ + + + ++ K+ +Q KP V LK TV G
Sbjct: 18180 EGGESDWVKTEE--VVVKEDLQ------KP------------VLDLKLSGVLTVKAGDTI 18219
Query: 1231 TMTCAFLGNPRPTV--TLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVE 1288
+ G P P V T K ++T + + ++ + + D G Y V
Sbjct: 18220 RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTAT 18279
Query: 1289 NELGKDRSSCTLTVYDK 1305
N G + T+ V DK
Sbjct: 18280 NTAGSFVAYATVNVLDK 18296
Score = 160 bits (406), Expect = 6e-39
Identities = 157/655 (23%), Positives = 275/655 (41%), Gaps = 61/655 (9%)
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDR-----PKPPQGRVEFLELSG 715
++ ++T + ++ + + ++ N +G SV+ + P PP G E +++
Sbjct: 27021 EECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITK 27079
Query: 716 SCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFR 775
+ + + W P +GG ++ + +E+R W K+ + + T + E YQ+R
Sbjct: 27080 NSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYR 27139
Query: 776 ILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVL 834
+ AVN+ G E E + A +PI+PPG ++ ++ D TK ++T+ W+ P DGG+ V
Sbjct: 27140 VCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 27199
Query: 835 GYIVERRKKGSNLWVPVN-KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSS 893
GY+VE R+ W V+ K ++ T+ V L Y FRV AVN AG G+P +
Sbjct: 27200 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 27259
Query: 894 VVAKDPVKPPGLVQD--LHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCT 951
V AKD ++ P + D L S + + + P +G PP +D K
Sbjct: 27260 VQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWR---KDEKNLGSDA 27316
Query: 952 KIPISGT----CYTVGGLIERQ--KYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFD 1005
+ I T T+ + KY I E GVGEP V+ + PAA +
Sbjct: 27317 RYSIENTDSSSLLTIPQVTRNDTGKYILTI----ENGVGEPKSSTVSVKVLDTPAACQ-- 27370
Query: 1006 LSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLIN 1063
+L+ V R L GSP + + +K + ++ + + F +
Sbjct: 27371 ---KLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI 27427
Query: 1064 STKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
+R+L +NE G V+ A+ P P +L + + +V L+W P
Sbjct: 27428 DLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWT-KP 27486
Query: 1121 DVQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGD 1177
D DG + Y++ ++ TW A + + V+ L FRV A+NE G
Sbjct: 27487 DF--DGGSVITEYVVERKGKGEQTWSHAGISK-TCEIEVSQLKEQSVLEFRVFAKNEKGL 27543
Query: 1178 SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT---PLKPHTVLRGQDCTMTC 1234
S+P+ + P K+ P P TV G + +
Sbjct: 27544 SDPVT------------------IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLEL 27585
Query: 1235 AFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVEN 1289
+ G P+P+++ K + + + ++ T TL I + G Y+V+++N
Sbjct: 27586 PYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN 27640
Score = 159 bits (402), Expect = 2e-38
Identities = 291/1327 (21%), Positives = 496/1327 (37%), Gaps = 203/1327 (15%)
Query: 76 VTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDS 135
+ PE A F V P + K I + E KI K H L + +++DS
Sbjct: 2891 IEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQG--KLHQLIIMNTSTEDS 2948
Query: 136 DNYKCIASNDHADAIYTVS-LLVT--------EGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
Y + ND A TV+ +++T E ++ + F+ + K
Sbjct: 2949 AEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEI 3008
Query: 187 NEKEMLEILSKVPKKDFEKVCMEYG-FTDFRGLLRKLKEMKKK-VEVEAIRILKPLEDKE 244
+ ++ +K + +G D+ + K VE I K ++D +
Sbjct: 3009 KSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIK 3068
Query: 245 TKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMND 304
+F+C E+ +P++ + W+K + L+I + +++ + L+I + M+D
Sbjct: 3069 VLEKKRAMFEC--EVSEPDITVQWMKDDQELQIT---DRIKIQKEKYVHRLLIPSTRMSD 3123
Query: 305 AGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNG 364
AG Y++ G +A+L V ++ K V+V E+Q AV E +++ + + W +G
Sbjct: 3124 AGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDG 3183
Query: 365 KELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRI-PIKFVS 423
E+ + + H + I + R SD+GE++ AG L ++ P + +
Sbjct: 3184 IEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQ 3243
Query: 424 NLKNVRVKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQL 482
L+ V V+ A ++ + + W K+ QLL G K H+G+ L++ +A
Sbjct: 3244 ELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFP 3303
Query: 483 SDGGEYTVVAMQDGDPTEYYSTAIVTVEERLA----------TVKSGMSDVHAATGSPAE 532
D YT A D ++ V V E ++ + + + D + G PA
Sbjct: 3304 EDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3363
Query: 533 LCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT-- 590
++ ++ W K+I ++ + ++L PE EG YTF A
Sbjct: 3364 FQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVG 3423
Query: 591 --ESEASVFIADPPTI------DPSVLEALAAHAITVKV-------GHTAHIKVPFRGKP 635
S A++ + P +I +E AA I K+ GH A + P
Sbjct: 3424 QVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAP 3483
Query: 636 LPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHL 695
+ W+K G E+ E ++ S+ + + L I D G K N++GS + T L
Sbjct: 3484 NVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 3543
Query: 696 SVLDRPKPPQGRVEFLELSGSCVHMKWKAPK---DNGGRPVTQFIVERRAVG---KKSWI 749
+V + P FL S KA K G PV + I ++ +W
Sbjct: 3544 TVTEAYPP-----TFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNW- 3597
Query: 750 KIGEVDGK-VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNP-----IEPPG 803
+I + + K + S +++ Y + A N G +D + E + P +EP
Sbjct: 3598 RISDAENKHILELSNLTIQDRGVYSCK--ASNKFG-ADICQAELIIIDKPHFIKELEPVQ 3654
Query: 804 FASQPQV---TDVTKE-AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGT 859
A +V V ++ VT+TW+ Q P Y + K + L +P+ K GT
Sbjct: 3655 SAINKKVHLECQVDEDRKVTVTWSKDGQK-LPPGKDYKICFEDKIATLEIPLAKLKDSGT 3713
Query: 860 -KCTVDGLLEDTEYEFRVIAVNKAGPGQPSV------PSSSVVAKDP--VKPPGLVQDLH 910
CT A N+AG S P S V DP + PG LH
Sbjct: 3714 YVCT---------------ASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLH 3758
Query: 911 VSDSSNSSISLAW----REPAEGDPPSGYILEMRA-EDTKEWSKCTKIPISGTCYTVGGL 965
+ I + W +E +E + Y + A D + K+ SG+
Sbjct: 3759 CKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITD----VKVEDSGS------- 3807
Query: 966 IERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIH 1025
+ AVN+ G + PP+ K L+ +VR GT +
Sbjct: 3808 -------YSCEAVNDVGSD---SCSTEIVIKEPPSFIK-----TLEPADIVR-GTNALLQ 3851
Query: 1026 AAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL--------INSTKRSDSGVYRILL 1077
SG+ P ++ W KD ++ I SK + F I S +D G Y ++
Sbjct: 3852 CEVSGTGPFEISWFKD------KKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVV 3905
Query: 1078 QNEFGEARYDIHVRVADFPRPPTNLRLFEEV----PNTVTL------------TWNHSPD 1121
NE G+ + PPT ++ +++ TVTL TW +
Sbjct: 3906 ANEVGKCGC---MATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQE 3962
Query: 1122 V-QEDGEAHYIIMKRDASTATWYTAAERV-FSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
V +EDG+ I M A ++ F KYT +A NE G
Sbjct: 3963 VIREDGK---IKMSFSNGVAVLIIPDVQISFGGKYT-------------CLAENEAG--- 4003
Query: 1180 PLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGN 1239
++ + +L K + + + V G T+ G
Sbjct: 4004 ----------SQTSVGELIVK----------EPAKIIERAELIQVTAGDPATLEYTVAGT 4043
Query: 1240 PRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCT 1299
P YK + A+ K+ + + V L + L DSG Y+ + NE+G T
Sbjct: 4044 PELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 4103
Query: 1300 LTVYDKD 1306
TV D+D
Sbjct: 4104 FTVLDRD 4110
Score = 159 bits (401), Expect = 2e-38
Identities = 300/1354 (22%), Positives = 492/1354 (36%), Gaps = 216/1354 (15%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P F+E + V A G+ A + +V G + ISW +E K + Y K +V
Sbjct: 7020 PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEH---TKLRSAPAYKMQFKNNVAS 7076
Query: 127 LEPLTSDDSD--NYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKK 184
L D SD Y C A N A+ + ++LV + ++ PP +K K
Sbjct: 7077 LVINKVDHSDVGEYSCKADNS-VGAVASSAVLVIKA-----------RKLPPFFARKLKD 7124
Query: 185 V-------------ANEKEMLEIL---SKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKK 228
V N E L++ V KD ++ F L+ L+ +
Sbjct: 7125 VHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDAN--LQTSFVHNVATLQILQTDQSH 7182
Query: 229 VEVEAIRILKPLEDKETKV-------DTTVVFDCI-----MELKDPNVKMIWIKGTEPLR 276
+ PL + + FD + L + + GT P++
Sbjct: 7183 IGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIK 7242
Query: 277 IQYSLGKYDVKQMGTKYMLVISN--------VNMNDAGIY----SLSVGDKRMSAELTVL 324
I ++ +++ G M ++ N V DAG Y S G SA+L V
Sbjct: 7243 ITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGV- 7301
Query: 325 DEPLKFLGEMKPVKVTERQTAV-FEIRLS-KKEPNFVWKFNGKELKRDDKYEITVSEDGL 382
EP +F+ +++P ++ ++ +E ++ E +W + E++ K+ ++ +
Sbjct: 7302 QEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDS-- 7359
Query: 383 THTLKIKDARLSDSGEFSAEAGNLVQKAQ----LTIDRIPIKFVSNLKNVRVKERSRACL 438
L++ + + DSG+++ EA N A L + PI F + + + L
Sbjct: 7360 VAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPI-FRKKPHPIETLKGADVHL 7418
Query: 439 ECELT-SKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGD 497
ECEL + + W KD + L G KY + E + I + +D GEY A D
Sbjct: 7419 ECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVG 7478
Query: 498 PTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLND-EKVEGVWLKD-GKEITD 555
+ + R +SD+ G +L + E + VW KD G+ + +
Sbjct: 7479 SDTCVGSIALKAPPRFV---KKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRE 7535
Query: 556 LPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT----ESEASVFIADPPTIDPSVLEA 611
+ I + L F + P + GKYT + K E A++ + +P TI
Sbjct: 7536 SDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEK---- 7591
Query: 612 LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCV 671
+I V G T ++ G P W+KDG E+T + + + + L I N
Sbjct: 7592 --PESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVA 7649
Query: 672 REDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLE---LSGSCVHMKWKAPKDN 728
DSG+ +++N G + T L V DR PP + E LSGS V M+ K
Sbjct: 7650 PSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKV---Y 7706
Query: 729 GGRPVT-QFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN---SEGV 784
G P++ + E + + D + N +EE + + +A N S+
Sbjct: 7707 GSPPISVSWFHEGNEISSGRKYQTTLTDNTCA-LTVNMLEESDSGDYTCIATNMAGSDEC 7765
Query: 785 SDPLETEEVFAGNPIEPPGFASQPQVTDV-TKEAVTITWNAPTQDGGAPVLGYIVERRKK 843
S PL EPP F +P DV T VT T IV+
Sbjct: 7766 SAPLTVR--------EPPSFVQKPDPMDVLTGTNVTFT--------------SIVKGTPP 7803
Query: 844 GSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSS---------- 893
S W + + + G +C V LED+ E + V+ + G+ + S+
Sbjct: 7804 FSVSWFKGSSELVPGDRCNVS--LEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTH 7861
Query: 894 VVAKDPVKPPGLVQDLHVSD----------SSNSSISLAWREPAEGDPPSGYILEMRAED 943
+ K P K + D + + IS+ W++ PS +
Sbjct: 7862 LYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPS----QRCNIT 7917
Query: 944 TKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPK 1003
T E S +IP S T G + N +G + + PP
Sbjct: 7918 TTEKSAILEIP-SSTVEDAGQ--------YNCYIENASGKD---SCSAQILILEPP---- 7961
Query: 1004 FDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKS----KNHSQ 1059
+ + V G + + +G+P V W K TK R T T N +
Sbjct: 7962 --YFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKG--DTKLRPTTTYKMHFRNNVAT 8017
Query: 1060 FLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL----- 1114
+ N +DSG Y +N GE + V + PP+ R +V TV L
Sbjct: 8018 LVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFD 8077
Query: 1115 -----TWNHSPDVQEDGEAHYIIMKRDASTATWY---TAAERVFSNKYTVTGLLPGRKYY 1166
+ S +DG+ +K + T + TA +F ++ G
Sbjct: 8078 CAISGSEPISVSWYKDGKP----LKDSPNVQTSFLDNTATLNIFKTDRSLAG-------Q 8126
Query: 1167 FRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLR 1226
+ A N IG + SA+L E K + P F L P +
Sbjct: 8127 YSCTATNPIGSASS-----------------SARLILTEGK---NPPFFDIRLAPVDAVV 8166
Query: 1227 GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVL 1286
G+ C G V+ K I + K+ + L + DSG Y+
Sbjct: 8167 GESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCY 8226
Query: 1287 VENELGKDRSSCTLTVYDKDDKSVVASITESLQK 1320
NE+GKD SCT + K ++ + S T+ L +
Sbjct: 8227 AVNEVGKD--SCTAQLNIK-ERLIPPSFTKRLSE 8257
Score = 154 bits (389), Expect = 5e-37
Identities = 157/664 (23%), Positives = 267/664 (40%), Gaps = 60/664 (9%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+ ++KP+ VTA E F V + P + W +S + IK S K S K H L L
Sbjct: 2796 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKS-VEIKPSDKHRLVSERKVHKLML 2853
Query: 128 EPLTSDDSDNYKCIASNDHADA-IYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
+ ++ D+ Y + A ++ +L +T+ + ++ P+ K
Sbjct: 2854 QNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKNIE-----------VPETKTASFE 2902
Query: 187 NEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVE---------------- 230
E + S K E E +G L +L M E
Sbjct: 2903 CEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSA 2962
Query: 231 ---VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
V I I L+D + T+ F+ + + + K W+K ++ S K ++
Sbjct: 2963 TLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYK--WLKNGVEIK---STDKCQMR 3017
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+ L I NV+ DA Y+ G +A L V ++F +K +KV E++ A+F
Sbjct: 3018 TKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMF 3077
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E +S+ + W + +EL+ D+ I + ++ H L I R+SD+G+++ AG V
Sbjct: 3078 ECEVSEPDITVQWMKDDQELQITDR--IKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNV 3135
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A+L ++ ++ S K V+V E+ RA +E E+ DV W KDG + +
Sbjct: 3136 STAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3195
Query: 468 H--EGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ E + + I + + SD GEYT VA ++ Y A V + V
Sbjct: 3196 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNA-----PEPPQVLQELQPVTV 3250
Query: 526 ATGSPAELCVVLNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
+G PA C V++ + W K+ + ++ + + G + L+ PE YT
Sbjct: 3251 QSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYT 3310
Query: 585 FRAKG----TESEASVFIADPPTIDPSVLEALAAHAITVKV-------GHTAHIKVPFRG 633
AK + AS+ + P + P + AI + G A + G
Sbjct: 3311 CEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG 3370
Query: 634 KPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
L KV+WY ++ M + ED L I+ ED G N G ++T
Sbjct: 3371 TDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTA 3429
Query: 694 HLSV 697
+LS+
Sbjct: 3430 NLSL 3433
Score = 152 bits (385), Expect = 2e-36
Identities = 151/601 (25%), Positives = 256/601 (42%), Gaps = 58/601 (9%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+ P ID L+ I ++ G + + VP +G+P P+V W K E+ + + +
Sbjct: 22938 EAPDID---LDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSS 22994
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
L + N R DSG L L+N G+ +A + + VLD P PP ++ E++ V
Sbjct: 22995 FTS--LVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVN-LKVTEITKDSVS 23051
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTN-----KVEEGKAYQF 774
+ W+ P +GG + +IVE+R +KS+ + VTN N +++EG +Y F
Sbjct: 23052 ITWEPPLLDGGSKIKNYIVEKREATRKSYAAV------VTNCHKNSWKIDQLQEGCSYYF 23105
Query: 775 RILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPV 833
R+ A N G+ P +T + + +PPG + V DVT+ +V+++W P DGG+ +
Sbjct: 23106 RVTAENEYGIGLPAQTADPIKVAEVPQPPGKIT---VDDVTRNSVSLSWTKPEHDGGSKI 23162
Query: 834 LGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSS 893
+ YIVE + K S W + ++ + + L + EY FRV+AVN+ G P +
Sbjct: 23163 IQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP 23220
Query: 894 VVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKI 953
+VAKD V P V+ S S L P G P +D + T+I
Sbjct: 23221 IVAKDLVIEPD-VKPAFSSYSVQVGQDLKIEVPISGRPKPTITW---TKDGLPLKQTTRI 23276
Query: 954 PISGTC-YTVGGLIERQK---YFFRIRAVNEAGVG----EPVELDKGVRAMPPPAAPKFD 1005
++ + T + E K + I N G E V LDK PP KFD
Sbjct: 23277 NVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK---PDPPKGPVKFD 23333
Query: 1006 ----LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
S L + + G G + I QK T + ++ + +
Sbjct: 23334 DVSAESITLSWNPPLYTG----------GCQITNYIVQKRDTTTTVWDVVSATVARTTLK 23383
Query: 1062 INSTKRSDSGVYRILLQNEFGEA-RYDIHVRVADF----PRPPTNLRLFEEVPNTVTLTW 1116
+ K +RI +N +G++ + VA + P PP +++ + W
Sbjct: 23384 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 23443
Query: 1117 NHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGRKYYFRVVARNEI 1175
+ + Y + +++ ++ W + + ++ L G +Y FRV A N +
Sbjct: 23444 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIV 23503
Query: 1176 G 1176
G
Sbjct: 23504 G 23504
Score = 151 bits (381), Expect = 5e-36
Identities = 228/1018 (22%), Positives = 388/1018 (38%), Gaps = 103/1018 (10%)
Query: 224 EMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQY---- 279
EM + V+ + I LE E +D + I + + +I KG P + +
Sbjct: 27255 EMNEPVQAKDI-----LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDE 27309
Query: 280 ----SLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGD-----KRMSAELTVLDEPLKF 330
S +Y ++ + +L I V ND G Y L++ + K + + VLD P
Sbjct: 27310 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 27369
Query: 331 LGEMKPVKVTERQTAVFE-----IRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHT 385
+ VK R T I N+V +++ D + T S ++H
Sbjct: 27370 --QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYV-------IEKRDATKRTWSV--VSHK 27418
Query: 386 LKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSK 445
+L D E + ++ + ++ I P + +K V R + T
Sbjct: 27419 CSSTSFKLIDLSEKTPFFFRVLAENEIGIGE-PCETTEPVKAAEVPAPIRDLSMKDSTKT 27477
Query: 446 DVTLRWKK---DGQLLMHGTKYSMNHEGKRAELI----------IEDAQLSDGG--EYTV 490
V L W K DG ++ T+Y + +GK + IE +QL + E+ V
Sbjct: 27478 SVILSWTKPDFDGGSVI--TEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRV 27535
Query: 491 VAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT-----GSPAELCVVLNDEKVEGV 545
A + ++ + +TV+E + T + +SD+ A G L + + +
Sbjct: 27536 FAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI 27595
Query: 546 -WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIA----D 600
WLKDG + + ++ K L + EH GKYT +V I
Sbjct: 27596 SWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLG 27655
Query: 601 PPT--IDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME- 657
PP+ P + + A ++ + VP ++T Y T + M
Sbjct: 27656 PPSKPKGPIRFDEIKADSVILS------WDVP-EDNGGGEITCYSIEKRETSQTNWKMVC 27708
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDR-----PKPPQGRVEFLE 712
+ + N V++ ++ +N +G + + ++ + P PP G+
Sbjct: 27709 SSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GKPVIYN 27767
Query: 713 LSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAY 772
++ + + W AP +GG VT F VE++ W K+ + + EG Y
Sbjct: 27768 VTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDY 27827
Query: 773 QFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA 831
QFR+ A NS G+S P + + A +P++PPG P DVT+E +T+ WN P +DGG+
Sbjct: 27828 QFRVYAENSAGLSSPSDPSKFTLAVSPVDPPG---TPDYIDVTRETITLKWNPPLRDGGS 27884
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGP-GQPSVP 890
++GY +E+R +G+ WV N + + TV GL YEFR+IA N G PS
Sbjct: 27885 KIVGYSIEKR-QGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQS 27943
Query: 891 SSSVVAKDPVKPPGLVQDLHVSDS--SNSSISLAWREPAEGDP-PSGYILEMRAEDTKEW 947
S ++ +D PP + D S SL + +G P P + E K
Sbjct: 27944 SGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM 28003
Query: 948 SKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLS 1007
+ + T V + + + A N +G + E+ V+ P +
Sbjct: 28004 NMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK-AEIKVKVQDTPGKVVGPIRFT 28062
Query: 1008 ARLKSHMV------VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE-TITKSKNHSQF 1060
M + G A H + W + + T K N +++
Sbjct: 28063 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEY 28122
Query: 1061 LINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
+ + GV R L + I V D P P + N++TLTW
Sbjct: 28123 QFRVSAVNKFGVGRPL---DSDPVVAQIQYTVPDAPGIPEPSNI---TGNSITLTWARPE 28176
Query: 1121 DVQEDGEAHYIIMKRDASTATWYTAAER--VFSNKYTVTGLLPGRKYYFRVVARNEIG 1176
YI+ +R+ + W + + ++ VTGL G +Y F V+A N G
Sbjct: 28177 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 28234
Score = 148 bits (374), Expect = 3e-35
Identities = 305/1410 (21%), Positives = 507/1410 (35%), Gaps = 188/1410 (13%)
Query: 1 MTTIHSRQMLQE--HVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVE---FFSLVT 55
+T + Q+L E +V + F S +Q S G + K+ S VE F LV
Sbjct: 5079 ITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138
Query: 56 RSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIF 115
+ I VEK + V E D V G + + W ++ G I S
Sbjct: 5139 EPAQI---------VEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKD-GKQIVPSRYFS 5188
Query: 116 YDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMD-FKKMLKKRA 174
N +++ + DS Y ND G D + ++L +
Sbjct: 5189 MSFENNVASFRIQSVMKQDSGQYTFKVENDF-------------GSSSCDAYLRVLDQNI 5235
Query: 175 PPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLK------EMKKK 228
PP+ KK K+ +K + + K F D + + K E
Sbjct: 5236 PPSFTKKLTKM--DKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVS 5293
Query: 229 VEVEAIRILKPLEDKETKVDTTVVFDC---IMELKDPNVKMIW----------------- 268
+EV + L+ + KV D I+ +K+P ++
Sbjct: 5294 LEVNNLE-LEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAI 5352
Query: 269 IKGTEPLRIQYSLGKYDVKQM----------GTKYMLVISNVNMNDAGIYSLSVGDKRMS 318
+KGT P +I++ K DV+ + G+ L + +V+ + G Y+ V + S
Sbjct: 5353 LKGTPPFKIKWF--KDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGS 5410
Query: 319 AELTVL---DEPLKFLGEMKPVKVTER-QTAVFEIRLS-KKEPNFVWKFNGKELKRDDKY 373
T + EP KF+ +++ K+ + ++ E +++ E VW N EL DKY
Sbjct: 5411 DSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKY 5470
Query: 374 EITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLT---IDRIPIKFVSNLKNVRV 430
+T + +++ + DSG+F EA N + I + P F S V
Sbjct: 5471 RMTFIDS--VAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVET 5528
Query: 431 KERSRACLECELT-SKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYT 489
+ + LECEL+ + + W KD + L KY + + + I + SD GEY
Sbjct: 5529 LKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYH 5588
Query: 490 VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGV-WLK 548
A + T + R S ++ + G PAEL + + V WLK
Sbjct: 5589 CKAQNEVGSDTCVCTVKLKEPPRFV---SKLNSLTVVAGEPAELQASIEGAQPIFVQWLK 5645
Query: 549 DGKE-ITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT----ESEASVFIADPPT 603
+ +E I + ++I V L F P + GKY + K E+ A++ + +P
Sbjct: 5646 EKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAV 5705
Query: 604 IDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQA 663
I A +TV VG T ++ G P V WYKDG +T ++ +
Sbjct: 5706 IVEK------AGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKIS 5759
Query: 664 LLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSG----SCVH 719
L I + R+D+G +++N+ G ++ T + V DR PP G SC+
Sbjct: 5760 SLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCI- 5818
Query: 720 MKWKAPKDNGGRPVT-QFIVERRAV--GKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRI 776
K G P++ + E+ + G K + V N ++ +
Sbjct: 5819 ---LECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSD---NVCTLQLNSLDSSDMGNYTC 5872
Query: 777 LAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTK-EAVTITWNAPTQDGGAPVLG 835
+A N G SD E V EPP F +P+ +V + VT T
Sbjct: 5873 VAANVAG-SD--ECRAVLTVQ--EPPSFVKEPEPLEVLPGKNVTFT-------------- 5913
Query: 836 YIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQ------PSV 889
++ W ++ ++G +C + EDT E + ++ + G+ +
Sbjct: 5914 SVIRGTPPFKVNWFRGARELVKGDRCNI--YFEDTVAELELFNIDISQSGEYTCVVSNNA 5971
Query: 890 PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSK 949
+S + VK P S S+ G P + + K
Sbjct: 5972 GQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEK 6031
Query: 950 CTKIPISGTC-YTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSA 1008
C + TC + +R + NEAG L V + PP
Sbjct: 6032 CNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGAL---VSTLEPP------YFV 6082
Query: 1009 RLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGV---PTKGRETITKSKNHSQFLINST 1065
+ G ++ + +G+P V W K PT T + N + + N
Sbjct: 6083 TELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYF-TNNVATLVFNKV 6141
Query: 1066 KRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEV------PNTVTLTWNHS 1119
+DSG Y +N G A R+ + PP+ R +++ P T+T N S
Sbjct: 6142 NINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGS 6201
Query: 1120 PDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
+Q ++++ D + T + + V + K T L +Y S
Sbjct: 6202 APIQVCWYRDGVLLRDDENLQTSF--VDNVATLKILQTDLSHSGQY--------SCSASN 6251
Query: 1180 PLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGN 1239
PL + + SA+L E K +P F V+ G+ C G
Sbjct: 6252 PLGTASS-----------SARLTAREPK---KSPFFDIKPVSIDVIAGESADFECHVTGA 6297
Query: 1240 PRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCT 1299
+T K + I + L I DSG Y+ N++GKD S
Sbjct: 6298 QPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQ 6357
Query: 1300 LTVYD------KDDKSVVASITESLQKKSK 1323
L+V + K + S VA ES+Q + K
Sbjct: 6358 LSVKEPPKFVKKLEASKVAKQGESIQLECK 6387
Score = 147 bits (371), Expect = 7e-35
Identities = 156/631 (24%), Positives = 257/631 (40%), Gaps = 77/631 (12%)
Query: 702 KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNF 761
KP RV + + + V + W P+D GG VT +++E + V + W K K+ +
Sbjct: 30035 KPQNPRVT--DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREY 30092
Query: 762 STNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGFASQPQVTD--VTKEAV 818
+ + +G Y+FR+LA N+ G +P E V +E P + + + ++
Sbjct: 30093 TLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGG 30152
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN--------KDPIQGTKCTVDGLLEDT 870
I P + P+ + E + + + K+ +G T D +LE
Sbjct: 30153 VIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLE-- 30210
Query: 871 EYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE-- 928
NK G + +V V P P G L D S+ ++WR PA+
Sbjct: 30211 ---------NKCG--KKAVYIKVRVIGSPNSPEG---PLEYDDIQVRSVRVSWRPPADDG 30256
Query: 929 GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE 988
G GYILE R W + GT V GL E +Y FR+ A N+ G+ +P++
Sbjct: 30257 GADILGYILERREVPKAAWYTIDS-RVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLK 30315
Query: 989 LDKGVRAMPP--PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPT 1045
++ V P P P + L V ++ +L S S P D + G
Sbjct: 30316 SEEPVTPKTPLNPPEPPSNPPEVLD---VTKSSVSL------SWSRPKDDGGSRVTGYYI 30366
Query: 1046 KGRETIT-KSKNHSQFLINSTKRSDSGV-------YRILLQNEFGEARYD------IHVR 1091
+ +ET T K H++ I +T + +G+ +RI+ QN+ G + +
Sbjct: 30367 ERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 30426
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA-HYIIMKRDASTATWYTA-AERV 1149
D P P L + ++VTL W P+ E Y + R + + W + ER+
Sbjct: 30427 PFDKPSQPGELEILSISKDSVTLQWE-KPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 30485
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
++T+ GLL +Y FRV A NE G S P + + KL E
Sbjct: 30486 KDKQFTIGGLLEATEYEFRVFAENETGLSRP----------RRTAMSIKTKLTSGE---- 30531
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
AP +K T G+ ++C +G P P + Y+ + + K+ +S T
Sbjct: 30532 --APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT 30589
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
L + T +D G Y+ + NE+G+ +S L
Sbjct: 30590 LTVMTEEQEDEGVYTCIATNEVGEVETSSKL 30620
Score = 147 bits (370), Expect = 9e-35
Identities = 238/1124 (21%), Positives = 420/1124 (37%), Gaps = 171/1124 (15%)
Query: 270 KGTEPLRIQYSLGKYDVKQMGTKYM--------LVISNVNMNDAGIYSLSV----GDKRM 317
+G+ PL I++ G ++ G+ Y+ L + V +D+G Y+ V G
Sbjct: 4230 QGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVEC 4289
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAV-FEIRLSKKEP-NFVWKFNGKELKRDDKYEI 375
SA L V EP F+ +++P ++ ++ A +++ P W N +E+K K+ +
Sbjct: 4290 SANLFV-KEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRM 4348
Query: 376 TVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQK---AQLTIDRIPIKFVSNLKNVRVKE 432
+ E T L++ D + DSGE+ EA N + + I + F K + V +
Sbjct: 4349 SFVES--TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLK 4406
Query: 433 RSRACLECELT-SKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVV 491
L E+ + + W KD +L G KY + L I +D GEY
Sbjct: 4407 EYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCR 4466
Query: 492 AMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGK 551
+ + +A VT+ E + +K S G+ A + + WLKD
Sbjct: 4467 VTNEVGSS--ICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSD 4524
Query: 552 EITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTES----EASVFIADPPTIDPS 607
EIT+ +++ + V L + +H+GKY +AK A + + +P TI
Sbjct: 4525 EITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEE 4584
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
+ +I V G A ++V F G W+KDG E+T + + + ++L I
Sbjct: 4585 AV------SIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKI 4638
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLE---LSGSCVHMKWKA 724
+ ++DSG +++ND G ++ ++VLD PP + + + GS + ++
Sbjct: 4639 ISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIV 4698
Query: 725 PKDNGGRPVT-QFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEG 783
G P++ Q+ + + + K D +++E + + A N G
Sbjct: 4699 A---GSHPISIQWFKDDQEISASEKYKFSFHD-NTAFLEISQLEGTDSGTYTCSATNKAG 4754
Query: 784 ---VSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVER 840
S L + EPP F +PQ DV T G AP+
Sbjct: 4755 HNQCSGHLTVK--------EPPYFVEKPQSQDVNPN--TRVQLKALVGGTAPM------- 4797
Query: 841 RKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQ----------PSVP 890
+ W NK+ G +V +DT + A G +
Sbjct: 4798 ----TIKWFKDNKELHSGAARSV--WKDDTSTSLELFAAKATDSGTYICQLSNDVGTATS 4851
Query: 891 SSSVVAKDP---VKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEW 947
+++ K+P +K P V L S+ + G P ++R +
Sbjct: 4852 KATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQIT------GTP------KIRVSWYLDG 4899
Query: 948 SKCTKIPISG-------TCYTVGGLIERQKYFFRIRAVNEAGVGE-PVELDKGVRAMPPP 999
++ T I G + + G + A N+AG +EL + PP
Sbjct: 4900 NEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIEL----KVKEPP 4955
Query: 1000 AAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQ 1059
LK VV+ + + + +G+PP +V W K+ + + T + S
Sbjct: 4956 T-----FIRELKPVEVVKY-SDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSV 5009
Query: 1060 FLINSTK--RSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNT------ 1111
F ++ TK SD+G Y+ ++ NE G V + + PP+ ++ E
Sbjct: 5010 FNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE---PPSFIKKIENTTTVLKSSAT 5066
Query: 1112 ----------VTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLP 1161
+++TW + ++ + YI D+ + + S +YT
Sbjct: 5067 FQSTVAGSPPISITWLKDDQILDEDDNVYISFV-DSVATLQIRSVDNGHSGRYTCQ---- 5121
Query: 1162 GRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKP 1221
A+NE G ++ +L+ ++ Q V K
Sbjct: 5122 ---------AKNESG----VERCYAFLLVQEPAQ-------------------IVEKAKS 5149
Query: 1222 HTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSG 1281
V T+ C G P V K I + F + + V + I + +DSG
Sbjct: 5150 VDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSG 5209
Query: 1282 DYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQKKSKHL 1325
Y+ VEN+ G L V D+++ S T+ L K K L
Sbjct: 5210 QYTFKVENDFGSSSCDAYLRVL---DQNIPPSFTKKLTKMDKVL 5250
Score = 146 bits (368), Expect = 1e-34
Identities = 152/685 (22%), Positives = 274/685 (40%), Gaps = 60/685 (8%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+F + VT PE +A F + A ++ W + I IK S K + K+H+L +
Sbjct: 11487 DFAVPLKDVTVPERRQARFECVLTREA--NVIWSKGPDI-IKSSDKFDIIADGKKHILVI 11543
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTVSLL------------VTEGQEKMDFKKMLKKRAP 175
DD Y A V+ + V EG+ ++ ++
Sbjct: 11544 NDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMH 11603
Query: 176 PAPKKKQKKVANEKEML-EILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAI 234
K K+ + +L K K + ++V ++ D + ++KE+ +++ +
Sbjct: 11604 VVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLD----DISQIKAQVKELSSTAQLKVL 11659
Query: 235 R----ILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
L DK + C + KD VK W K E + KY +K G
Sbjct: 11660 EADPYFTVKLHDKTAVEKDEITLKCEVS-KDVPVK--WFKDGEEI---VPSPKYSIKADG 11713
Query: 291 TKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIR 350
+ +L I ++ D G Y G + A +TV +K + V+V +TA FEI
Sbjct: 11714 LRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIE 11773
Query: 351 LSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKA 410
LS+ + + WK G+ L EI EDG H L + + +L +GE S +A N A
Sbjct: 11774 LSEPDVHGQWKLKGQPLTASPDCEII--EDGKKHILILHNCQLGMTGEVSFQAANAKSAA 11831
Query: 411 QLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEG 470
L + +P+ F++ L +V+V E+ A ECE++ + T RW K Q + ++ + +G
Sbjct: 11832 NLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDG 11891
Query: 471 KRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSP 530
+ ++I+ A D +Y A + +++ + +E + + DV A
Sbjct: 11892 TKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKFLTPLKDVTAKEKES 11945
Query: 531 AELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
A V L+ + + W K+ + + + + +G H + F + + + A G
Sbjct: 11946 AVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGM 12005
Query: 591 ESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTE 650
SEA + + + DP L + K ++ P V W+KDG E+
Sbjct: 12006 SSEAKLTVLEG---DPYFTGKLQDYTGVEKDEVILQCEISKADAP---VKWFKDGKEIKP 12059
Query: 651 EERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP---KPPQGR 707
+ ++ + +L + ++ D G + D G+ + L + DR P
Sbjct: 12060 SKNAVIKADGKKRMLILKKALKSDIG----QYTCDCGTDKTSGKLDIEDREIKLVRPLHS 12115
Query: 708 VEFL---------ELSGSCVHMKWK 723
VE + E+S +H WK
Sbjct: 12116 VEVMETETARFETEISEDDIHANWK 12140
Score = 143 bits (361), Expect = 1e-33
Identities = 192/826 (23%), Positives = 330/826 (39%), Gaps = 134/826 (16%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA-KIFYDSINKEHVL 125
P+ V P+PV EG+ A FR RV G +P ++W + K ++ YD I H L
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGI---HYL 1897
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPK------ 179
+ S D+ K A N + V L E Q++ DF+ +L++ P P+
Sbjct: 1898 DIVDCKSYDTGEVKVTAENPEGVIEHKVKL---EIQQREDFRSVLRRAPEPRPEFHVHEP 1954
Query: 180 -------------------------KKQKKVANEK---EMLEILSKVPKKDFEKVCMEYG 211
K+ +++ +EK E E+ SK ++ E
Sbjct: 1955 GKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAIT 2014
Query: 212 FTDFRGLLR--KLKEMKKKVEVEAIRILKPLEDKETK----------------------- 246
+ + + +E+ +K + E + K L ++E K
Sbjct: 2015 AVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPS 2074
Query: 247 VDTTVVFDCIME---------------LKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGT 291
++ +F+ I + P+ + W K ++I+ S Y
Sbjct: 2075 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNG--VKIERSDRIYWYWPEDN 2132
Query: 292 KYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPL-KFLGEMKPVKVTERQT-A 345
LVI +V D+ + G+ A L V + L F E++ V E+ T A
Sbjct: 2133 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2192
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSA---E 402
FE S+ W +G E+ DKY + D H L I SD+ ++S E
Sbjct: 2193 TFECETSEPFVKVKWYKDGMEVHEGDKYRM--HSDRKVHFLSILTIDTSDAEDYSCVLVE 2250
Query: 403 AGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGT 462
N+ A+L ++ ++FV L+++ V E LEC ++ +++ +W + L
Sbjct: 2251 DENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNG 2310
Query: 463 KYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSD 522
KY++ R L ++D D GEY+ V DG T T + ++ R + G+SD
Sbjct: 2311 KYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKT----TCKLKMKPRPIAILQGLSD 2364
Query: 523 VHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGK 582
G +L V ++ E VEGVW+KDG+E+ + IV H L+ M E G
Sbjct: 2365 QKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGN 2424
Query: 583 YTFR----AKGTESEASVFIAD--PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPL 636
Y+F T SV+ D P D +V+E K + VP +
Sbjct: 2425 YSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEG-------TKAVLECKVSVP----DV 2473
Query: 637 PKVTWYKDGMEVTEEERV-SMERGEDQALLTISNCVREDSG---LILLKLKNDHGSATAT 692
V WY + ++ ++RV ++ +G Q L+ I+ D G LI+ +++ + +
Sbjct: 2474 TSVKWYLNDEQIKPDDRVQAIVKGTKQRLV-INRTHASDEGPYKLIVGRVETNCNLSVEK 2532
Query: 693 LHL--SVLDRPKPPQGRVEF-LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
+ + + D V F +ELS S + + W KD +P +++ +E K +
Sbjct: 2533 IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNF-KDKEIKPSSKYKIEAHGKIYKLTV 2591
Query: 750 --KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEV 793
+ + +GK T ++ + GK L V +S PL + V
Sbjct: 2592 LNMMKDDEGKYTFYAGENMTSGK------LTVAGGAISKPLTDQTV 2631
Score = 143 bits (360), Expect = 1e-33
Identities = 157/639 (24%), Positives = 271/639 (42%), Gaps = 54/639 (8%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P GR E + ++ + V +KWK P +GG +T +IVE++ + W+K + T
Sbjct: 24602 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 24661
Query: 761 FSTNKVEEGKAYQFRILAVNSEG-VSDPLETE-EVFAGNPIEPPGFASQPQVTDVTKEAV 818
F+ + + E + Y+FR++A N+ G S+P ++ + A + I+ P + P+ DV
Sbjct: 24662 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA 24721
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLED---TEYEFR 875
T+ G P+ + K G L + I+ T +++D T+
Sbjct: 24722 GETFVLEADIRGKPIPDVVWS--KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 24779
Query: 876 VIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPS 933
++ ++ G G S+P + V P P G L V+ + LAW P + G S
Sbjct: 24780 ILKLSNVG-GTKSIPITVKVLDRPGPPEG---PLKVTGVTAEKCYLAWNPPLQDGGANIS 24835
Query: 934 GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV 993
YI+E R W++ + + Y V L+ +Y FR+ AVN+ G+GEP+E
Sbjct: 24836 HYIIEKRETSRLSWTQVST-EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT 24894
Query: 994 RAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKG 1047
P PP+ P ++SA K MVV + G+ I +K D +
Sbjct: 24895 ACNPYKPPGPPSTP--EVSAITKDSMVVTWARPV----DDGGTEIEGYILEKRDKEGVRW 24948
Query: 1048 RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADF---PRPPTN 1101
+ K+ + + S +R+ +N G + + R D P PP+N
Sbjct: 24949 TKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSN 25008
Query: 1102 LRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAER--VFSNKYTVT 1157
++ + ++V+L W S + + G Y++ ++A+ W T + ++TVT
Sbjct: 25009 PKVTDTSRSSVSLAW--SKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVT 25066
Query: 1158 GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT 1217
L +Y FR+ A N G EP + ++ +++I+ +L +K V
Sbjct: 25067 KLKENTEYNFRICAINSEGVGEPATLPGS-VVAQERIEPPEIELDADLRK--------VV 25117
Query: 1218 PLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTL 1277
L+ LR + G P P V K + +T ++ TS LVI T
Sbjct: 25118 VLRASATLR-----LFVTIKGRPEPEVKWEKAEGILTDRAQI--EVTSSFTMLVIDNVTR 25170
Query: 1278 KDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
DSG Y++ +EN G + + V D V +I E
Sbjct: 25171 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIRE 25209
Score = 141 bits (356), Expect = 4e-33
Identities = 163/756 (21%), Positives = 295/756 (39%), Gaps = 74/756 (9%)
Query: 581 GKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVT 640
GKYT + S AS+ + P + +T K VP P
Sbjct: 26253 GKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVT-KESAVLSWDVPENDGGAPVKN 26311
Query: 641 WYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG---SATATLHLSV 697
++ + E +++ VS+ ++ ++N + +N+ G A + +
Sbjct: 26312 YHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI 26371
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
++P PP+ ++ +S V + W P+ +GG + ++VE G+K+W+K K
Sbjct: 26372 TEKPSPPE-KLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA--K 26428
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGFASQ--PQVTDVT 814
T+ + + E Y FR+ A N G+SDP E V +EPP + P T
Sbjct: 26429 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYV 26488
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE- 873
+ + + P G P+ + R VP+ T+ T + L + +
Sbjct: 26489 RAGSNLKVDIPIS--GKPLPKVTLSRDG------VPLKATMRFNTEITAENLTINLKESV 26540
Query: 874 ------FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA 927
+ + A N +G + + + VV P P G V +SD + S++L W P
Sbjct: 26541 TADAGRYEITAANSSGTTKAFI--NIVVLDRPGPPTGPVV---ISDITEESVTLKWEPPK 26595
Query: 928 E--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
G + YIL R T W++ + ++ T V L ++Y FRI+A N G+ +
Sbjct: 26596 YDGGSQVTNYILLKRETSTAVWTEVSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISD 26654
Query: 986 PVELDKGVRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDV 1036
++ +P PP+ P R + H V G + + +
Sbjct: 26655 HIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSI 26714
Query: 1037 IWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH---VRVA 1093
+WQK + + ++ + F + + +R+ +N G + V
Sbjct: 26715 LWQK------ANKLVIRT---THFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAI 26765
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSN 1152
D PP N+R+ + N+V+L+W YI+ +RD W A+ V
Sbjct: 26766 DACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTET 26825
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHA 1212
++ ++GL +Y FRV ARN +G I + S + P D
Sbjct: 26826 QFIISGLTQNSQYEFRVFARNAVGS----------------ISNPSEVVGPITCIDSYGG 26869
Query: 1213 PRFVTPLKPHTVLR---GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
P PL+ V++ G + G P PT+ YK D + N+ +T+ + +
Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 26929
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
++I +SG Y + + N +G ++ + + DK
Sbjct: 26930 ILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 26965
Score = 141 bits (355), Expect = 5e-33
Identities = 259/1145 (22%), Positives = 436/1145 (38%), Gaps = 157/1145 (13%)
Query: 231 VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGK-YDVKQM 289
++ +K LE ++ ++ V +C ++ +D V + W K + L GK Y +
Sbjct: 3641 IDKPHFIKELEPVQSAINKKVHLECQVD-EDRKVTVTWSKDGQKL----PPGKDYKICFE 3695
Query: 290 GTKYMLVISNVNMNDAGIY----SLSVGDKRMSAELTVLDEPLKFLGEMKP-VKVTERQT 344
L I + D+G Y S G SA +TV EP F+ ++ P + ++
Sbjct: 3696 DKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVR-EPPSFVKKVDPSYLMLPGES 3754
Query: 345 AVFEIRLSKKEP--NFVWKFNGKELKRDDKYEIT-VSEDGLTHTLKIKDARLSDSGEFSA 401
A +L K P W N KEL + + V+ + + L I D ++ DSG +S
Sbjct: 3755 ARLHCKL-KGSPVIQVTWFKNNKELSESNTVRMYFVNSEAI---LDITDVKVEDSGSYSC 3810
Query: 402 EAGNLVQKAQLTIDRI---PIKFVSNLKNVRVKERSRACLECELTSKD-VTLRWKKDGQL 457
EA N V + + + P F+ L+ + + A L+CE++ + W KD +
Sbjct: 3811 EAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQ 3870
Query: 458 LMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVK 517
+ KY + + L I +D GEY V + +T ++ + T
Sbjct: 3871 IRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLL---KEPPTFV 3927
Query: 518 SGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMG 576
+ D+ A G L V E + W+K + I + +++ V LI P +
Sbjct: 3928 KKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQ 3987
Query: 577 PEHEGKYTFRAK---GTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRG 633
GKYT A+ G+++ I P ++E A I V G A ++ G
Sbjct: 3988 ISFGGKYTCLAENEAGSQTSVGELIVKEPA---KIIER--AELIQVTAGDPATLEYTVAG 4042
Query: 634 KPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
P K WYKDG + ++ + + A L + DSG ++ N+ GS++
Sbjct: 4043 TPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCET 4102
Query: 694 HLSVLDRP-----KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPV-TQFIVERRAVGKKS 747
+VLDR P V+ + ++G+C + K G P+ + + + +
Sbjct: 4103 TFTVLDRDIAPFFTKPLRNVDSV-VNGTC-RLDCKIA---GSLPMRVSWFKDGKEIAASD 4157
Query: 748 WIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQ 807
+I V+G + +V+ A F A NS G D V EPP F ++
Sbjct: 4158 RYRIAFVEG-TASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIV-----QEPPSFVTK 4211
Query: 808 PQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLL 867
P DV + T G P+ + W NK+ + G C +
Sbjct: 4212 PGSKDVLPGSAVCL--KSTFQGSTPL-----------TIRWFKGNKELVSGGSCYITKEA 4258
Query: 868 EDTEYEFRVIAVNKAGPGQPSVP--------SSSVVAKDPVKPPGLVQDLHVSDSSNSSI 919
++ E ++ + +G V S+++ K+P V+ L S
Sbjct: 4259 LESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPAT---FVEKLEPSQLLKKGD 4315
Query: 920 SLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTC---YTVGGLIERQKYFFRIR 976
+ G PP + KE SK + T T G+ + +Y
Sbjct: 4316 ATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYM--CE 4373
Query: 977 AVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
A NEAG + + P +F LK + V+ + A +G+PP ++
Sbjct: 4374 AQNEAGSDHCSSI--VIVKESPYFTKEFKPIEVLKEYDVM-------LLAEVAGTPPFEI 4424
Query: 1037 IWQKDG-VPTKGRETITKSKNHSQFL-INSTKRSDSGVYRILLQNEFGEARYDIHVRVAD 1094
W KD + GR+ T ++H L I +D+G Y+ + NE G + V + +
Sbjct: 4425 TWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLRE 4484
Query: 1095 FPRPPTNLRLFEEVPN----------------TVTLTW-NHSPDVQEDGEAHYIIMKRDA 1137
PP+ ++ E + +T+TW S ++ ED I M +
Sbjct: 4485 ---PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDN---IRMTFEN 4538
Query: 1138 STATWYTAAERV-FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQD 1196
+ A+ Y + V KY A+N+ G IQ
Sbjct: 4539 NVASLYLSGIEVKHDGKYVCQ-------------AKNDAG-----------------IQR 4568
Query: 1197 LSAKLKPYEKKDWRHAPRFVT-PLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA 1255
SA L E P +T V +G T+ F G T +K +T
Sbjct: 4569 CSALLSVKE-------PATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTL 4621
Query: 1256 NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASIT 1315
SK+ + T V L I + KDSG+Y+ V+N++G RSSC + + D + S T
Sbjct: 4622 GSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVG--RSSCKARI-NVLDLIIPPSFT 4678
Query: 1316 ESLQK 1320
+ L+K
Sbjct: 4679 KKLKK 4683
Score = 140 bits (353), Expect = 8e-33
Identities = 280/1344 (20%), Positives = 494/1344 (36%), Gaps = 191/1344 (14%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P FVEKPQ + +A V G A I W +++ +A+ + + L+
Sbjct: 4768 PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKD-DTSTSLE 4826
Query: 127 LEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPP---------- 176
L + DS Y C SND A +L V E + +KK +P
Sbjct: 4827 LFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQ------FIKKPSPVLVLRNGQSTT 4880
Query: 177 -------APKKK-------QKKVANEKEMLEILSKVPKKDFEKVCMEYGFT------DFR 216
PK + + A +K + + + +E T +
Sbjct: 4881 FECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDA 4940
Query: 217 GLLRKLKEMKKKVEVEAIRILKPLE-----DKETKVDTTVVFDCIMELKDPNVKMIWIKG 271
G E+K K IR LKP+E D E + + T P ++ W+K
Sbjct: 4941 GTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGT---------PPFEVTWLKN 4991
Query: 272 TEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTV---LDEPL 328
+R S KY + + + L I+ + +D G Y V ++ S + L EP
Sbjct: 4992 NREIR---SSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPP 5048
Query: 329 KFLGEMKPVKVTERQTAVFEIRLSKKEP-NFVWKFNGKELKRDDKYEITVSEDGLTHTLK 387
F+ +++ + +A F+ ++ P + W + + L DD I+ + TL+
Sbjct: 5049 SFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDS--VATLQ 5106
Query: 388 IKDARLSDSGEFSAEAGN---LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELT- 443
I+ SG ++ +A N + + + + P + V K+V V E+ LEC +
Sbjct: 5107 IRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAG 5166
Query: 444 SKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYS 503
+ ++ ++W KDG+ ++ +SM+ E A I+ D G+YT D + +
Sbjct: 5167 TPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDA 5226
Query: 504 TAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIV 562
V + + ++ + GS + C V + W KDGKEI+ ++V
Sbjct: 5227 YLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLV 5286
Query: 563 KQGAVHKLIFPSMGPEHEGKYTFRAKGTESEAS----VFIADPPT--IDPSVLEALAAHA 616
L ++ E YT + + + + + +PP+ + P +A+
Sbjct: 5287 CHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIP--- 5343
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
T K +G P K+ W+KD +E+ + + + L + + +G
Sbjct: 5344 -----DSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTG 5398
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELS-----GSCVHMKWKAPKDNGGR 731
+ ND GS + T L V + PK V+ LE S G ++ K G
Sbjct: 5399 QYTCHVTNDVGSDSCTTMLLVTEPPK----FVKKLEASKIVKAGDSSRLECKI----AGS 5450
Query: 732 PVTQFIVERRA--VGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE 789
P + + R + ++ +D V N + + F A N G S
Sbjct: 5451 PEIRVVWFRNEHELPASDKYRMTFIDS-VAVIQMNNLSTEDSGDFICEAQNPAG-STSCS 5508
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAP---VLGYIVERRKKGSN 846
T+ + EPP F+S P + + K A + + G P V+ Y +R+ + S
Sbjct: 5509 TKVIVK----EPPVFSSFPPIVETLKNAEV---SLECELSGTPPFEVVWYKDKRQLRSSK 5561
Query: 847 LWVPVNKDPIQGTKCTVDGLLEDTEY--EFRVIAVNKAGPGQPSVPSSSVVAKDPVK-PP 903
+ +K+ ++ L DT E+ A N+ G S + V +K PP
Sbjct: 5562 KYKIASKN----FHTSIHILNVDTSDIGEYHCKAQNEVG-------SDTCVCTVKLKEPP 5610
Query: 904 GLVQDLHVSDSSNSSISLAWREPAE------GDPPSGYILEMRAEDTKEWSKCTKIPISG 957
V L+ S+++ EPAE G P E+ S+ +I
Sbjct: 5611 RFVSKLN-------SLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVE 5663
Query: 958 TCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRA-MPPPAAPKFDLSARLKSHMVV 1016
T+ F + N ++ D G+R M + + M V
Sbjct: 5664 NVATL--------QFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTV 5715
Query: 1017 RAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNH--------SQFLINSTKRS 1068
G + +G+P V W KDG + +T S+ H S I S +R
Sbjct: 5716 TVGETCTLECKVAGTPELSVEWYKDG------KLLTSSQKHKFSFYNKISSLRILSVERQ 5769
Query: 1069 DSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA 1128
D+G Y +QN G++ V V+D PP+ R + + G +
Sbjct: 5770 DAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVL-------------GAS 5816
Query: 1129 HYIIMKRDAST---ATWYTAAERVFSN-KYTVTGLLPGRKYYFRVVARNEIG--DSEPLD 1182
+ K S+ W+ ++ S KY T + V ++ DS +
Sbjct: 5817 CILECKVAGSSPISVAWFHEKTKIVSGAKYQTT--------FSDNVCTLQLNSLDSSDMG 5868
Query: 1183 SRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP 1242
+ N + A L E P FV +P VL G++ T T G P
Sbjct: 5869 NYTCVAANVAGSDECRAVLTVQEP------PSFVKEPEPLEVLPGKNVTFTSVIRGTPPF 5922
Query: 1243 TVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
V ++G + + V L + + SG+Y+ +V N G ++SCT +
Sbjct: 5923 KVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG--QASCTTRL 5980
Query: 1303 YDKDDKSVVASITESLQKKSKHLM 1326
+ K+ + + +++ + K ++
Sbjct: 5981 FVKEPAAFLKRLSDHSVEPGKSII 6004
Score = 139 bits (349), Expect = 2e-32
Identities = 190/815 (23%), Positives = 305/815 (37%), Gaps = 84/815 (10%)
Query: 528 GSPAELCVVLNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
G P L ++ V W K G + G Q+ + L+ P+ + GKY+
Sbjct: 18621 GCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG-QVDLVDTMAFLVIPNSTRDDSGKYSLT 18679
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
E +VF+ P + L +T H + P +VT Y +
Sbjct: 18680 LVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSW--APPENDGGSQVTHYI--V 18735
Query: 647 EVTEEERVSMERGEDQALLT---ISNCVREDSGLILLKLKNDHGSATAT------LHLSV 697
E E +R + + T ++N V + + N++G T L
Sbjct: 18736 EKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 18795
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKS--WIKIGEVD 755
L P PP+ ++E E++ + + W P +GG + +I R + + W + V
Sbjct: 18796 LSEPDPPR-KLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVV- 18853
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVT 814
K + ++EGK Y+FR+ A N+ GVS P E E V+ A + PP Q+T
Sbjct: 18854 -KDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQIT--I 18910
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEF 874
K + A P + + ++ + V+K D +D+ Y +
Sbjct: 18911 KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY-Y 18969
Query: 875 RVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPP 932
+ A N +G + + A P +PP +SD + SL+W P E G
Sbjct: 18970 SLTAENSSGTDTQKIKVVVMDAPGPPQPP-----FDISDIDADACSLSWHIPLEDGGSNI 19024
Query: 933 SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG 992
+ YI+E +W +C VG LI Q+Y FR+RA N G+ EP+ K
Sbjct: 19025 TNYIVEKCDVSRGDWVTALASVTKTSC-RVGKLIPGQEYIFRVRAENRFGISEPLTSPKM 19083
Query: 993 VRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT 1052
V P F + + K+ V + CI A+ PD G P G
Sbjct: 19084 VAQFP------FGVPSEPKNARVTKVNKD-CIFVAWDR---PD---SDGGSPIIGYLIER 19130
Query: 1053 KSKNH------SQFLINSTKRSDSGV-------YRILLQNEFGEA---RYDIHVRVADFP 1096
K +N + L+ ST+ +G+ +RI N+ G + + +V
Sbjct: 19131 KERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPV 19190
Query: 1097 RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWY---TAAERVFSNK 1153
PP + + +TV+L W Y + W TA ++ +
Sbjct: 19191 DPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEE 19250
Query: 1154 YTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ---DLSAKLKPYEKKDWR 1210
YT TGL +Y FR +AR + S P + D I + + DLS +K
Sbjct: 19251 YTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL----- 19305
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
TV G + + G P PTV+ K + +CTL
Sbjct: 19306 ------------TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTL 19353
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+ + KDSGDY++ EN G ++ L V DK
Sbjct: 19354 ELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 19388
Score = 137 bits (346), Expect = 5e-32
Identities = 219/998 (21%), Positives = 382/998 (38%), Gaps = 131/998 (13%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P K+ W K + I + K V + T LVI N +D+G YSL++ G+K +
Sbjct: 18634 PAPKVTWRK----VGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAV 18689
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITV 377
+ VLD P + ++K VT+ V + V + ++ + D K TV
Sbjct: 18690 FVNVRVLDTPGP-VSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTV 18748
Query: 378 SEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRAC 437
+ + + + + + F A N T P+ L + R
Sbjct: 18749 TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE---PDPPRKL 18805
Query: 438 LECELTSKDVTLRW---KKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQ 494
E+T TL W +DG + G S E + A+ E + + D V ++
Sbjct: 18806 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD-LSLVVTGLK 18864
Query: 495 DGDPTEYYSTA--------------IVTVEERL----------ATVKSGMS---DVHAAT 527
+G ++ A + +E+L T+K+G + H
Sbjct: 18865 EGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAH-VY 18923
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA 587
G P C W K E+ + + K + LI + + G Y+ A
Sbjct: 18924 GKPHPTC----------KWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTA 18973
Query: 588 K---GTESE---ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW 641
+ GT+++ V A P P + + A A ++ + HI + G + +
Sbjct: 18974 ENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL----SWHIPLEDGGSNI--TNY 19027
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG-SATATLHLSVLDR 700
+ +V+ + V+ + + + + ++ +N G S T V
Sbjct: 19028 IVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQF 19087
Query: 701 P-----KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVD 755
P +P RV +++ C+ + W P +GG P+ +++ER+ W+K +
Sbjct: 19088 PFGVPSEPKNARV--TKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTL 19145
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVT 814
+ T + + EG Y FRI A+N G S P + TE V A P++PPG +P+V DVT
Sbjct: 19146 VRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPG---KPEVIDVT 19202
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLLEDTEY 872
K V++ W P DGG+ ++GY VE K + WV N P I + T GL E +Y
Sbjct: 19203 KSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQY 19262
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSI------------- 919
+FR IA PS PS V PP + DL V+ S ++
Sbjct: 19263 QFRAIARTAVNISPPSEPSDPVTILAENVPPRI--DLSVAMKSLLTVKAGTNVCLDATVF 19320
Query: 920 -----SLAWR------EPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+++W+ +PAEG + R T E + T
Sbjct: 19321 GKPMPTVSWKKDGTLLKPAEGIK----MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 19376
Query: 969 QKYFFRIRAVNEAGVGEPVELDK--GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHA 1026
+ +++ +++ G V+++K RAM P D + + +++V + T+ A
Sbjct: 19377 KSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWA 19436
Query: 1027 AFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
S + P + + E + + + QF I + + G + + + Y
Sbjct: 19437 QVSATVP---------ITSCSVEKLIEGHEY-QFRICAENKYGVG-DPVFTEPAIAKNPY 19485
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA 1146
D R PP + ++ +T++W D Y++ KR+ W
Sbjct: 19486 DPPGRC----DPPVISNITKD---HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVN 19538
Query: 1147 ER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ + TGL G +Y FRV A N+ G +P D+
Sbjct: 19539 RKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDA 19576
Score = 137 bits (344), Expect = 9e-32
Identities = 160/649 (24%), Positives = 257/649 (39%), Gaps = 75/649 (11%)
Query: 690 TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
T L ++ +DRP P+ + + + V++KW+ P +GG P + VERR G W
Sbjct: 18090 TPILAINPIDRPGEPEN-LHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWE 18148
Query: 750 KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQ 809
++ + K T++ ++ E + Y+FR+ N G SD ++TEEV ++ P +
Sbjct: 18149 RVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLS 18208
Query: 810 VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLE 868
K TI A + P + + ++ V D +K ++
Sbjct: 18209 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 18268
Query: 869 DTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE 928
++ V A N AG V ++V D PG V++L + D S+ ++ W P +
Sbjct: 18269 SDGGKYVVTATNTAGS---FVAYATVNVLDK---PGPVRNLKIVDVSSDRCTVCWDPPED 18322
Query: 929 --GDPPSGYILEMRAEDTKEWSKCTKIPIS-GTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
G YILE WS + ++ GT TV LIE +Y FR+RA N+ G G
Sbjct: 18323 DGGCEIQNYILEKCETKRMVWSTYSATVLTPGT--TVTRLIEGNEYIFRVRAENKIGTGP 18380
Query: 986 PVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPT 1045
P E + P A K+D R V + +PP + DG +
Sbjct: 18381 PTE------SKPVIAKTKYDKPGRPDPPEVTKVSKE---EMTVVWNPP-----EYDGGKS 18426
Query: 1046 KGRETITKSKNHSQFLINSTKRS--------------DSGVYRILLQNEFGEARYDIHVR 1091
+ K + HS + K + +R+ +NE G + R
Sbjct: 18427 ITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR 18486
Query: 1092 VA------DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKR----DAS 1138
+ P PPTN R+ + +++TL W DG A Y++ R DAS
Sbjct: 18487 PVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPV---YDGGAPIIGYVVEMRPKIADAS 18543
Query: 1139 TATWY---TAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ 1195
+ AA ++ ++TVT L ++Y FRV A+N++G P
Sbjct: 18544 PDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP--------------A 18589
Query: 1196 DLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA 1255
+L +KP E + + K V G + G P P VT K ++
Sbjct: 18590 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 18649
Query: 1256 NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
K + + LVIP T DSG YS+ + N G+ + V D
Sbjct: 18650 R-KGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLD 18697
Score = 135 bits (341), Expect = 2e-31
Identities = 152/639 (23%), Positives = 252/639 (39%), Gaps = 77/639 (12%)
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKA 771
+++ + + +KW PKDNG P+ + +E+R V W ++ + + + + EG
Sbjct: 14913 DVTSNSMLVKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 14971
Query: 772 YQFRILAVNSEG---VSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQD 828
Y FR+ A N+ G S P + + A +PI PPG P+VTD + + + W P +
Sbjct: 14972 YVFRVCAENAAGPGKFSPPSDPKT--AHDPISPPG-PPIPRVTDTSSTTIELEWEPPAFN 15028
Query: 829 GGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPS 888
GG ++GY V+++ G+N W + I+ + TV + E +Y+ RV AVN AG G P
Sbjct: 15029 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPG 15088
Query: 889 VPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWS 948
VA +P +PP + D+ V R PA ++ R TK W+
Sbjct: 15089 ETQPVTVA-EPQEPPAVELDVSVKGGIQIMAGKTLRIPA--------VVTGRPVPTKVWT 15139
Query: 949 KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP-------AA 1001
K G L + + + +E + + + D G + AA
Sbjct: 15140 K-----------EEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAA 15188
Query: 1002 PK---FDLSARLKSHMVVRAGTALCIHAAFSGSPPPD---------VIWQKDGVPTKGRE 1049
+ FD+ + V +C+ + S P D +I +KD R+
Sbjct: 15189 ARVEVFDVPGPVLDLKPVVTNRKMCL---LNWSDPEDDGGSEITGFIIERKDAKMHTWRQ 15245
Query: 1050 TITKSKNHSQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRL 1104
I ++ I +R++ +N+FG E + V P P L
Sbjct: 15246 PIETERSKCD--ITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTY 15303
Query: 1105 FEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGR 1163
E +T+TL W YII KR + +R+ + + V L +
Sbjct: 15304 TERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQ 15363
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHT 1223
Y FRV A NEIG+SEP S ++ +D + KL+ + D
Sbjct: 15364 MYEFRVKAVNEIGESEP--SLPLNVVIQDDEVPPTIKLRLSVRGD------------TIK 15409
Query: 1224 VLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS------KFWYNSTSGVCTLVIPTCTL 1277
V G+ + G P P + K + I + K + + L IP
Sbjct: 15410 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 15469
Query: 1278 KDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
+D G Y+V N LG + + VYD+ ++T+
Sbjct: 15470 EDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 15508
Score = 135 bits (339), Expect = 3e-31
Identities = 264/1312 (20%), Positives = 494/1312 (37%), Gaps = 133/1312 (10%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P FV+K ++ G + + ++G + W ++ G ++ES I+ L+
Sbjct: 7492 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQ 7551
Query: 127 LEPLTSDDSDNYKCIASNDHA--DAIYTVSLL----VTEGQEKMDFKK----MLKKRAPP 176
+ ++ Y C ND + T+S+L + E E + L+
Sbjct: 7552 FSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAG 7611
Query: 177 APKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRI 236
P+ K + KE+ +K F KV L+ + V + +
Sbjct: 7612 TPELSTKWFKDGKELTSD-NKYKISFFNKVSG----------LKIINVAPSDSGVYSFEV 7660
Query: 237 LKPLEDKETKV-----DTTVVFDCIMELKDPN-------VKMIWIKGTEPLRIQY----- 279
P+ D TV +LK+ N V + G+ P+ + +
Sbjct: 7661 QNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGN 7720
Query: 280 ---SLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPLKFLG 332
S KY L ++ + +D+G Y+ G SA LTV EP F+
Sbjct: 7721 EISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVR-EPPSFVQ 7779
Query: 333 EMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGK-ELKRDDKYEITVSEDGLTHTLKIKDA 391
+ P+ V F + P V F G EL D+ +++ ED + L++ D
Sbjct: 7780 KPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSL-EDSVAE-LELFDV 7837
Query: 392 RLSDSGEFSAEAGNLVQKAQLTID---RIPIKFVSNLKNVRVKERSRACLECELT-SKDV 447
S SGE++ N KA T + P KFV L + +++ LE T + +
Sbjct: 7838 DTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPI 7897
Query: 448 TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIV 507
++ WKK+G + + ++ K A L I + + D G+Y +++ + S I+
Sbjct: 7898 SVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCY-IENASGKDSCSAQIL 7956
Query: 508 TVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGA 566
+E + + V + G A L C + ++ W K ++ ++ +
Sbjct: 7957 ILEPPYFVKQ--LEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNN 8014
Query: 567 VHKLIFPSMGPEHEGKYTFRAKGTESE--ASVFIA-DPPTIDPSVLEALAAHAITVKVGH 623
V L+F + G+Y +A+ + E AS F+ + PS L + VG
Sbjct: 8015 VATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQL--RDVQETVGL 8072
Query: 624 TAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLK 683
G V+WYKDG + + V ++ A L I R +G
Sbjct: 8073 PVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTAT 8132
Query: 684 NDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPV-TQFIVERRA 742
N GSA+++ L + + PP + + G +P+ + + R
Sbjct: 8133 NPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSRE 8192
Query: 743 VGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPP 802
+ +I ++ + + KV++G + Q+ AVN G T ++ + PP
Sbjct: 8193 IRSGGKYQISYLENSA-HLTVLKVDKGDSGQYTCYAVNEVGKDSC--TAQLNIKERLIPP 8249
Query: 803 GFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSN----LWVPVNKDPIQG 858
F + +++ +E +G + + +E R GS W N +
Sbjct: 8250 SFTKR--LSETVEET----------EGNS----FKLEGRVAGSQPITVAWYKNNIEIQPT 8293
Query: 859 TKCTVDGLLEDTEYEFRVIAVNKAG--------PGQPSVPSSSVVAKDPVKPPGLVQDLH 910
+ C + + R +N AG ++ +SS+V K+P KPP Q L
Sbjct: 8294 SNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT 8353
Query: 911 -VSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT-VGGLIER 968
V+ S + L+ +G P + K +C+ SGT + + +
Sbjct: 8354 PVTVSEGEYVQLSCH--VQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKA 8411
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRAMPP--PAAPKFDLSARL------KSHMVVRAGT 1020
+ +A N AG + + ++ P PA K + RL +S VV T
Sbjct: 8412 DSGDYVCKASNVAG-SDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTT 8470
Query: 1021 ALCIHAAFSGSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILL 1077
A I A G P P+V W K + GR I + + ++ I T ++DSG+YR +
Sbjct: 8471 ATFI-AKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVA 8529
Query: 1078 QNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQ----EDGEAHYIIM 1133
NE GE +++++V + + E++ + +P ++ E+ E + +
Sbjct: 8530 FNEHGEIESNVNLQVDERKKQ-------EKIEGDLRAMLKKTPILKKGAGEEEEIDIMEL 8582
Query: 1134 KRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQ 1193
++ + ++ Y +T G F ++ +++ ++ L+ + +D+
Sbjct: 8583 LKNVDPKEY-----EKYARMYGITD-FRGLLQAFELLKQSQEEETHRLEIEEIERSERDE 8636
Query: 1194 IQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAF-LGNPRPTVTLYKGDVN 1252
+ ++ + ++ TVL+ D + P ++ YKG
Sbjct: 8637 KEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEK 8696
Query: 1253 ITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
+ + KF + TL + C LKD G+Y ++ G +S LTV +
Sbjct: 8697 LEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLV----CGPHIASAKLTVIE 8744
Score = 130 bits (328), Expect = 6e-30
Identities = 172/696 (24%), Positives = 279/696 (40%), Gaps = 100/696 (14%)
Query: 67 PEFVEKPQPV-TAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVL 125
P+FV+K + A +G+ ++ G+ + +SW R + ES K IN +L
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDS-ELHESWKYNMSFINSVALL 6422
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLV------TEGQEKMDFKK----MLKKRAP 175
+ +++DS +Y C A N DA + +L V T+ + K +L+
Sbjct: 6423 TINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEIS 6482
Query: 176 PAPK------KKQKKVANEKEMLEILSKVPKKDFE------------------KVCMEYG 211
P K +K+V N K+ K+ K F+ K E G
Sbjct: 6483 GTPPFEVVWVKDRKQVRNSKKF-----KITSKHFDTSLHILNLEASDVGEYHCKATNEVG 6537
Query: 212 FTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKG 271
+D K KE R +K L D T + V I+E P + ++W+K
Sbjct: 6538 -SDTCSCSVKFKEPP--------RFVKKLSDTSTLIGDAVELRAIVEGFQP-ISVVWLKD 6587
Query: 272 -------TEPLRIQY-------SLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRM 317
+E RI + LG + G KY+ I N DAG+ +
Sbjct: 6588 RGEVIRESENTRISFIDNIATLQLGSPEASNSG-KYICQIKN----DAGM-------REC 6635
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFE-IRLSKKEPNFVWKFNGKELKRDDKYEIT 376
SA LTVL EP + + + +P+ VT E + E + W +G+EL D K+ IT
Sbjct: 6636 SAVLTVL-EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHIT 6694
Query: 377 VSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTI-----DRI-PIKFVSNLKNVRV 430
+LKI A +SD G +S E N V K+ T+ DRI P F+ LK+V
Sbjct: 6695 FINK--VASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNA 6752
Query: 431 KERSRACLECELT-SKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYT 489
+ LEC ++ S +++ W +DG ++ G K + L + + SD G YT
Sbjct: 6753 ILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYT 6812
Query: 490 VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKD 549
VA E +A++TV+E + ++ S S V+ + W K
Sbjct: 6813 CVAANVAGSDE--CSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKG 6870
Query: 550 GKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEAS----VFIADPPTID 605
+E+ I + V +L + P G Y+ AS +F+ +P T
Sbjct: 6871 SRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFV 6930
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALL 665
+ + +V+ G ++ + G P V+W KD +++ ER S+ E +L
Sbjct: 6931 KRLAD------FSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTIL 6984
Query: 666 TISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP 701
I ED ++N+ G +SVL+ P
Sbjct: 6985 EILESTIEDYAQYSCLIENEAGQDICEALVSVLEPP 7020
Score = 130 bits (328), Expect = 6e-30
Identities = 143/631 (22%), Positives = 251/631 (39%), Gaps = 64/631 (10%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P G ++++++ + +KW P +GG + + +E+R G + W++ D
Sbjct: 27854 PVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQ-GNERWVRCNFTDVSECQ 27912
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE--VFAGNPIEPPGFASQPQVTD--VTKE 816
++ + G Y+FRI+A N+ G P + + PP P+ D + K
Sbjct: 27913 YTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKS 27972
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
++ A Q P + + + + + + + D + T V D + V
Sbjct: 27973 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTV 28031
Query: 877 IAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGD--PPSG 934
A N +G + + V +D P +V + ++ + ++L W P P +
Sbjct: 28032 EAKNASGSAKAEI---KVKVQDT--PGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITH 28086
Query: 935 YILEMRAEDTKEWS----KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELD 990
YI+E R W+ KC YT LI +Y FR+ AVN+ GVG P++ D
Sbjct: 28087 YIIEKRETSRLAWALIEDKC-----EAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSD 28141
Query: 991 KGVRAMP--PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKG 1047
V + P AP + + + + + GS I ++ + T+
Sbjct: 28142 PVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR---PESDGGSEIQQYILERREKKSTRW 28198
Query: 1048 RETITKSK-NHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV------ADFPRPPT 1100
+ I+K + ++F + + + ++ +N G R+ + P PPT
Sbjct: 28199 VKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPT 28258
Query: 1101 NLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTA-AERVFSNKYTVT 1157
+++ + TV+L W S V + G YII A W+ AE +YTVT
Sbjct: 28259 VVKVTDTSKTTVSLEW--SKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVT 28316
Query: 1158 GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ----DLSAKLKPYEKKDWRHAP 1213
L G +Y FRV A N G + + T + D++ D+ A K
Sbjct: 28317 DLQAGEEYKFRVSAINGAGKGDSCEVTGT-IKAVDRLTAPELDIDANFK----------- 28364
Query: 1214 RFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIP 1273
+ H V G + A+ G P PT K D N++ + ++T TL +
Sbjct: 28365 ------QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI--HTTDSFSTLTVE 28416
Query: 1274 TCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
C D+G Y++ VEN G + T+ V D
Sbjct: 28417 NCNRNDAGKYTLTVENNSGSKSITFTVKVLD 28447
Score = 130 bits (327), Expect = 8e-30
Identities = 192/809 (23%), Positives = 309/809 (38%), Gaps = 115/809 (14%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
W K EI D + + + L+ ++ GKYT + + S F+
Sbjct: 22976 WGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDT 23033
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW----YKDGMEVTEEERVSMERGED 661
PS L IT K +TW G ++ E
Sbjct: 23034 PSPPVNLKVTEIT---------------KDSVSITWEPPLLDGGSKIKNYIVEKREATRK 23078
Query: 662 QALLTISNCVRED----------SGLILLKLKNDHG---SATATLHLSVLDRPKPPQGRV 708
++NC + S + +N++G A + V + P+PP G++
Sbjct: 23079 SYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKI 23137
Query: 709 EFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEE 768
+++ + V + W P+ +GG + Q+IVE +A + W + V K + +
Sbjct: 23138 TVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARV--KSLQAVITNLTQ 23195
Query: 769 GKAYQFRILAVNSEGVSDP--LETEEVFAGNPIEP---PGFASQP-QVTDVTKEAV---- 818
G+ Y FR++AVN +G SDP L V IEP P F+S QV K V
Sbjct: 23196 GEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG 23255
Query: 819 ----TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEF 874
TITW T+DG P+ K+ + + V D + T ++ +D ++
Sbjct: 23256 RPKPTITW---TKDG-LPL--------KQTTRINVT---DSLDLTTLSIKETHKDDGGQY 23300
Query: 875 RVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPP 932
+ N G S+ ++ DP K P + D S SI+L+W P G
Sbjct: 23301 GITVANVVGQKTASIEIVTLDKPDPPKGP-----VKFDDVSAESITLSWNPPLYTGGCQI 23355
Query: 933 SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG 992
+ YI++ R T W ++ T V L +Y FRI A N G +E D
Sbjct: 23356 TNYIVQKRDTTTTVWD-VVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI 23414
Query: 993 VRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGV 1043
V P PP P ++ ++ H V G + I ++W
Sbjct: 23415 VAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW----- 23469
Query: 1044 PTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQN--EFGEARYDIHVRVADFP-RPPT 1100
TK +TI + +QF + + +R+ +N G+A + VA P PP
Sbjct: 23470 -TKVNKTII---HDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG 23525
Query: 1101 NLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAA-ERVFSNKYTVT 1157
N +TL W + V + G YI+ KRD W A+ V ++TV+
Sbjct: 23526 TPEPIMVKRNEITLQW--TKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVS 23583
Query: 1158 GLLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
GL ++Y FRV+A+N G S+P DS + KD+++ P D P+F
Sbjct: 23584 GLTEDQRYEFRVIAKNAAGAISKPSDSTGP-ITAKDEVE------LPRISMD----PKFR 23632
Query: 1217 TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
+ V G+ + G P PT+ +GD I +++ +T L++
Sbjct: 23633 DTI---VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAI 23689
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
D G Y + N G + V D+
Sbjct: 23690 RIDGGQYILRASNVAGSKSFPVNVKVLDR 23718
Score = 130 bits (326), Expect = 1e-29
Identities = 117/443 (26%), Positives = 200/443 (45%), Gaps = 28/443 (6%)
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K+ V I KPL D+ VF+C E+ +P+ K W++ + L + ++ +
Sbjct: 2614 KLTVAGGAISKPLTDQTVAESQEAVFEC--EVANPDSKGEWLRDGKHLPLTNNIRS---E 2668
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G K L+I+ ++D G Y+ V + SA+L V E +K +K + VTE Q AVF
Sbjct: 2669 SDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKV--EAVKIKKTLKNLTVTETQDAVF 2726
Query: 348 EIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+ L+ V W NG L+ ++KY I+V G ++L+IK+ + D + G L
Sbjct: 2727 TVELTHPNVKGVQWIKNGVVLESNEKYAISVK--GTIYSLRIKNCAIVDESVYGFRLGRL 2784
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
A+L ++ + K + K+V E + E ++ V ++W + K+ +
Sbjct: 2785 GASARLHVETV--KIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRL 2842
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
E K +L++++ SD GEYT V Q E + V E L K+ M ++
Sbjct: 2843 VSERKVHKLMLQNISPSDAGEYTAVVGQ----LECKAKLFV---ETLHITKT-MKNIEVP 2894
Query: 527 TGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
A ++ V +WLK+G EI +IV QG +H+LI + E +YTF
Sbjct: 2895 ETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV 2954
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
+ A++ + P + S+L+ + A K T + V + G W K+G+
Sbjct: 2955 CGNDQVSATLTVT--PIMITSMLKDINAEE---KDTITFEVTVNYEG---ISYKWLKNGV 3006
Query: 647 EVTEEERVSMERGEDQALLTISN 669
E+ ++ M + L I N
Sbjct: 3007 EIKSTDKCQMRTKKLTHSLNIRN 3029
Score = 130 bits (326), Expect = 1e-29
Identities = 162/646 (25%), Positives = 269/646 (41%), Gaps = 69/646 (10%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P GR E + ++ + V ++WK P +GG +T +IVE++ + + W+K + T+
Sbjct: 22438 PCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTH 22497
Query: 761 FSTNKVEEGKAYQFRILAVNSEGV-SDPLE-TEEVFAGNPIEPPGFASQPQVTD--VTKE 816
F + E Y+FR++A N+ GV S+P E T + A + ++PP + P+ D V
Sbjct: 22498 FEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHA 22557
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
+ +A P + +I ++ + + + + D + D+
Sbjct: 22558 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG---NY 22614
Query: 877 IAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSG 934
I K G+ SV + V P P G V +S + +LAW+ P + G
Sbjct: 22615 ILKAKNVAGERSVTVNVKVLDRPGPPEGPVV---ISGVTAEKCTLAWKPPLQDGGSDIIN 22671
Query: 935 YILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVR 994
YI+E R W+ + +C V L+E +Y FRI AVN+ GVGEP+E + V
Sbjct: 22672 YIVERRETSRLVWTVVDANVQTLSC-KVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVA 22730
Query: 995 AMP--PPAAPKF-DLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI 1051
P P APK +++ K M+V A+ GS + +K + +E I
Sbjct: 22731 KNPFVVPDAPKAPEVTTVTKDSMIVVWERP----ASDGGSEILGYVLEK-----RDKEGI 22781
Query: 1052 TKSKNHSQFLINSTKRSDSGV-------YRILLQNEFG------EARYDIHVRVADFPRP 1098
++ H + LI + +G+ +R+ +N G + Y P P
Sbjct: 22782 RWTRCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGP 22840
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDG--EAHYIIMKRDASTATWYTAAERVFSNKYT- 1155
P N ++ + ++V L+W S + + G YI+ K D S W NK
Sbjct: 22841 PNNPKVIDITRSSVFLSW--SKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNI 22898
Query: 1156 -VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ----DLSAKLKPYEKKDWR 1210
V LL +Y FR+ A N+ G E D +I +++++ DL +L+
Sbjct: 22899 EVEKLLEKHEYNFRICAINKAGVGEHADVPGP-IIVEEKLEAPDIDLDLELRKIINIRAG 22957
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
+ R P+K G P P V K D I + + TS +L
Sbjct: 22958 GSLRLFVPIK-----------------GRPTPEVKWGKVDGEIRDAAII--DVTSSFTSL 22998
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
V+ DSG Y++ +EN G + T+ V D V +TE
Sbjct: 22999 VLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTE 23044
Score = 129 bits (324), Expect = 2e-29
Identities = 180/796 (22%), Positives = 290/796 (36%), Gaps = 82/796 (10%)
Query: 543 EGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPP 602
E W ++ E TD +QI K +L + GKY + + + S F+
Sbjct: 24055 EITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 24112
Query: 603 TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQ 662
P + LA + G K + D E T + ++ +
Sbjct: 24113 LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK-NYVIDKRESTRKAYANVSSKCSK 24171
Query: 663 ALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ--GRVEFLELSGSCVHM 720
+ N + +N+ G + + +PP G+V ++S + +
Sbjct: 24172 TSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASL 24231
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W+ P+ +GG V ++VE + G + W + E KV N + G+ YQFR+ A N
Sbjct: 24232 MWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAE--SKVCNAVVTGLSSGQEYQFRVKAYN 24289
Query: 781 SEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA------PVL 834
+G SDP G P+ QP ++ + +N + G PV+
Sbjct: 24290 EKGKSDPR-----VLGVPVIAKDLTIQP--------SLKLPFNTYSIQAGEDLKIEIPVI 24336
Query: 835 GYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY-----------EFRVIAVNKAG 883
G R + + WV + Q T+ V+ T ++ V A N AG
Sbjct: 24337 G-----RPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG 24391
Query: 884 PGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRA 941
++ S +V + P P G V+ + S + ++W PA G S YI+E R
Sbjct: 24392 TATENL--SVIVLEKPGPPVGPVR---FDEVSADFVVISWEPPAYTGGCQISNYIVEKRD 24446
Query: 942 EDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMP---- 997
T W + ++ T + L +Y FRI A N G P++ + P
Sbjct: 24447 TTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP 24505
Query: 998 -PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT 1052
PP P ++ ++ H V G I ++W K T ++T
Sbjct: 24506 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLN-KTPIQDTKF 24564
Query: 1053 KSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTV 1112
K+ + L K S + I ++ E D PP N V
Sbjct: 24565 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFV-----ARDPCDPPGRPEAIVITRNNV 24619
Query: 1113 TLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVA 1171
TL W YI+ K+D W A+ V ++TV+GL+ ++Y FRV+A
Sbjct: 24620 TLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIA 24679
Query: 1172 RNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDC 1230
RN G+ SEP DS + +D+I +A L P K V G+
Sbjct: 24680 RNAAGNFSEPSDSSGA-ITARDEIDAPNASLDPKYK-------------DVIVVHAGETF 24725
Query: 1231 TMTCAFLGNPRPTVTLYKGDVNITAN-SKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVEN 1289
+ G P P V K + ++ ST TLV+ C D G Y + + N
Sbjct: 24726 VLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSN 24785
Query: 1290 ELGKDRSSCTLTVYDK 1305
G T+ V D+
Sbjct: 24786 VGGTKSIPITVKVLDR 24801
Score = 123 bits (309), Expect = 1e-27
Identities = 159/650 (24%), Positives = 271/650 (41%), Gaps = 64/650 (9%)
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
L + L P P+ R+ + E + S + + WK P+ NGG P+ +I+E+R K + ++
Sbjct: 15287 LAVDPLGPPTSPE-RLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 15345
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVT- 811
+ T+F ++E + Y+FR+ AVN G S+P V + PP + V
Sbjct: 15346 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG 15405
Query: 812 DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP-----VNKDPIQG----TKCT 862
D K + P G P+ +E K + + P + K+ + T+ +
Sbjct: 15406 DTIKVKAGEPVHIPADVTGLPMPK--IEWSKNETVIEKPTDALQITKEEVSRSEAKTELS 15463
Query: 863 VDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ + + + + V A N+ G +V V D PP ++L V+D S L
Sbjct: 15464 IPKAVREDKGTYTVTASNRLGSVFRNV---HVEVYDRPSPP---RNLAVTDIKAESCYLT 15517
Query: 923 WREPAE--GDPPSGYILEMRAEDTK--EWSKCTKIPISGTCYTVGGLIERQKYFFRIRAV 978
W P + G + Y+++ R K EW + T + Y + LI +Y FR+RAV
Sbjct: 15518 WDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKR-YGIWKLIPNGQYEFRVRAV 15576
Query: 979 NEAGVGEPVELDKGVRAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
N+ G+ + + DK V P PP PK + AR K M+V L +G P
Sbjct: 15577 NKYGISDECKSDKVVIQDPYRLPGPPGKPK--VLARTKGSMLVSWTPPLD-----NGGSP 15629
Query: 1034 PDVIW---QKDGVP---TKGRETITK-SKNHSQFLINSTKRSDSGVYRILLQNEFG---- 1082
W +++G P R ITK +F + +R + N G
Sbjct: 15630 ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPP 15689
Query: 1083 EARYDIHVRVADF--PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDAS 1138
D V P PP+ + ++ ++++L W P ++ G YI+ ++
Sbjct: 15690 SEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWK--PPAKDGGSPIKGYIVEMQEEG 15747
Query: 1139 TATWYTAAER---VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ 1195
T W E + + + V L RKY FRV A NE G+SEP D+ T I IQ
Sbjct: 15748 TTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDT--TGEIPATDIQ 15805
Query: 1196 DLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTC-AFLGNPRPTVTLYKGDVNIT 1254
+ +D + + ++ V++G+ + F G + + D+
Sbjct: 15806 EEPEVFIDIGAQDCLVC-KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 15864
Query: 1255 ANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
A + NS+ ++IP C +G YS+ +N+ G+ ++C + V D
Sbjct: 15865 AQLETAENSS----VIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMD 15910
Score = 123 bits (308), Expect = 1e-27
Identities = 280/1305 (21%), Positives = 461/1305 (35%), Gaps = 147/1305 (11%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISW-KRESGIPIKESAKIFYDSINKEHVL 125
P FV + +P+ A GD + +V G + +SW K ++ + + ++ N L
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFT--NNVATL 6136
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAP----PAPKKK 181
+ +DS Y C A N A + E Q F + LK P
Sbjct: 6137 VFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTC 6196
Query: 182 QKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLE 241
+ + ++ V +D E ++ F D L+ L+ + PL
Sbjct: 6197 RLNGSAPIQVCWYRDGVLLRDDEN--LQTSFVDNVATLKILQTDLSHSGQYSCSASNPLG 6254
Query: 242 DKETKVDTTV---VFDCIMELKDPNVKMI---------WIKGTEPLRIQYSL-------- 281
+ T ++K ++ +I + G +P+RI +S
Sbjct: 6255 TASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPG 6314
Query: 282 GKYDVKQMGTKYMLVISNVNMNDAGIYSLS----VGDKRMSAELTVLDEPLKFLGEMKPV 337
G Y + +G L I V D+G Y+ VG SA+L+V EP KF+ +++
Sbjct: 6315 GNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSV-KEPPKFVKKLEAS 6373
Query: 338 KVTERQTAV-FEIRLS-KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSD 395
KV ++ ++ E ++S E W N EL KY ++ L I +A D
Sbjct: 6374 KVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINS--VALLTINEASAED 6431
Query: 396 SGEFSAEAGNLVQKAQ----LTIDRIPIKFVSNLKNVRVKERSRACLECELT-SKDVTLR 450
SG++ EA N V A LT+ P+ F V + S L+CE++ + +
Sbjct: 6432 SGDYICEAHNGVGDASCSTALTVKAPPV-FTQKPSPVGALKGSDVILQCEISGTPPFEVV 6490
Query: 451 WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQD-GDPTEYYSTAIVTV 509
W KD + + + K+ + + L I + + SD GEY A + G T + V
Sbjct: 6491 WVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDT---CSCSVKF 6547
Query: 510 EERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKD-GKEITDLPGMQIVKQGAV 567
+E VK +SD G EL +V + + VWLKD G+ I + +I +
Sbjct: 6548 KEPPRFVKK-LSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNI 6606
Query: 568 HKLIFPSMGPEHEGKYTFRAKGT----ESEASVFIADPPTIDPSVLEALAAHAITVKVGH 623
L S + GKY + K E A + + +P I +TV G+
Sbjct: 6607 ATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEK------PEPMTVTTGN 6660
Query: 624 TAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLK 683
++ G P W+KDG E++ + + + A L I D GL ++K
Sbjct: 6661 PFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVK 6720
Query: 684 NDHGSATATLHLSVLDRPKPPQGRVEFLELS---GSCVHMKWKAPKDNGGRPVTQFIVE- 739
N G + T+ + V DR PP + +++ G+ V ++ + +G P++ +
Sbjct: 6721 NSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRV---SGSAPISVGWFQD 6777
Query: 740 --RRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGN 797
G K E V + + +E + +A N G SD E V
Sbjct: 6778 GNEIVSGPKCQSSFSE---NVCTLNLSLLEPSDTGIYTCVAANVAG-SD--ECSAVLTVQ 6831
Query: 798 PIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQ 857
EPP F P +V +++T+ + ++ W +++ +
Sbjct: 6832 --EPPSFEQTPDSVEVL-PGMSLTFTS------------VIRGTPPFKVKWFKGSRELVP 6876
Query: 858 GTKCTVDGLLEDTEYEFRVIAVNKAGPGQPS------VPSSSVVAKDPVKPPGLVQDLHV 911
G C + LED E + V G S S+S VK P
Sbjct: 6877 GESCNIS--LEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLA 6934
Query: 912 SDSSNSSISLAWREPAEGDPP--SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQ 969
S + + G PP +I + E T S + IE
Sbjct: 6935 DFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDY 6994
Query: 970 KYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFS 1029
+ + NEAG L V + PP H+ G +
Sbjct: 6995 AQYSCL-IENEAGQDICEAL---VSVLEPP------YFIEPLEHVEAVIGEPATLQCKVD 7044
Query: 1030 GSPPPDVIWQKDGVPTKGRET--ITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYD 1087
G+P + W K+ + + N + +IN SD G Y N G
Sbjct: 7045 GTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASS 7104
Query: 1088 IHVRVADFPRPPTNLRLFEEVPNTV------TLTWNHSPDVQEDGEAHYIIMKRDASTAT 1141
+ + PP R ++V T+ N S +Q +++K DA+ T
Sbjct: 7105 AVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQT 7164
Query: 1142 WYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKL 1201
+ N T+ L + + + + S PL + + SAKL
Sbjct: 7165 SFV------HNVATLQILQTDQSH----IGQYNCSASNPLGTASS-----------SAKL 7203
Query: 1202 KPYEKKDWRHAPRFVTPLKPHTV--LRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKF 1259
E P F LKP +V G+ T C G +T K + I +
Sbjct: 7204 ILSE----HEVPPFF-DLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNY 7258
Query: 1260 WYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
TL + D+G Y+ N GKD S L V +
Sbjct: 7259 KMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE 7303
Score = 123 bits (308), Expect = 1e-27
Identities = 164/700 (23%), Positives = 281/700 (40%), Gaps = 79/700 (11%)
Query: 57 SSNIPAGDSV---------PEFVEKPQPVTAPEGDKAV-FRARVQGNAKPHISWKRESGI 106
+SNI DS P F++K +P + D+ + ++ G+ + + W ++
Sbjct: 7286 ASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDE-T 7344
Query: 107 PIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDF 166
I+ES+K ++ VL++ L+ +DS +Y C A N A + SL V E
Sbjct: 7345 EIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE------- 7397
Query: 167 KKMLKKRAPPAPKKKQKKVANEKEM-----LEILSKVPKKDFE-----KVCMEYGFTDFR 216
+ +K+ P K V E E+ + K++ K+ E T
Sbjct: 7398 PPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIH 7457
Query: 217 GL-----------LRKLKEMKKKVEVEAI------RILKPLEDKETKVDTTVVFDCIMEL 259
L + ++ V +I R +K L D T V V +E
Sbjct: 7458 ILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEG 7517
Query: 260 KDPNVKMIWIKGT-EPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GD 314
+P + ++W K E +R ++ + + T L S V +AG Y+ + G
Sbjct: 7518 AEP-ISVVWFKDKGEIVRESDNIWISYSENIAT---LQFSRVEPANAGKYTCQIKNDAGM 7573
Query: 315 KRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLS-KKEPNFVWKFNGKELKRDDKY 373
+ A L+VL EP + + + +KVT T E ++ E + W +GKEL D+KY
Sbjct: 7574 QECFATLSVL-EPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKY 7632
Query: 374 EITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTI-----DR-IPIKFVSNLKN 427
+I+ LKI + SDSG +S E N V K T DR +P F LK
Sbjct: 7633 KISFFNK--VSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKE 7690
Query: 428 VRVKERSRACLECEL-TSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGG 486
S +EC++ S +++ W +G + G KY L + + SD G
Sbjct: 7691 TNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSG 7750
Query: 487 EYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGV- 545
+YT +A E +A +TV E + V+ + TG+ ++ V
Sbjct: 7751 DYTCIATNMAGSDE--CSAPLTVREPPSFVQK-PDPMDVLTGTNVTFTSIVKGTPPFSVS 7807
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEAS----VFIADP 601
W K E+ + + +V +L + G+YT +AS ++I P
Sbjct: 7808 WFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAP 7867
Query: 602 PTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGED 661
+ +++ G ++ F G P VTW K+G+ VT +R ++ E
Sbjct: 7868 AKF------VKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK 7921
Query: 662 QALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP 701
A+L I + ED+G ++N G + + + +L+ P
Sbjct: 7922 SAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPP 7961
Score = 122 bits (307), Expect = 2e-27
Identities = 148/640 (23%), Positives = 248/640 (38%), Gaps = 83/640 (12%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
+RP PP G++ ++++ + V + W+ P+ +GG + +IVE + G W V KV
Sbjct: 22047 ERPLPP-GKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATV--KV 22103
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGF----------ASQ 807
T + + +G+ Y FR+ A N +G+SDP + V A + + PP F A +
Sbjct: 22104 TEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGE 22163
Query: 808 PQVTDVT---KEAVTITW---NAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
DV + +TW N P + E + S L +
Sbjct: 22164 DLKVDVPFIGRPTPAVTWHKDNVPLKQ----TTRVNAESTENNSLLTIK----------- 22208
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
D ED + + V N AG ++ + +V+ D PP + + + + SI+L
Sbjct: 22209 --DACREDVGH-YVVKLTNSAGE---AIETLNVIVLDKPGPP--TGPVKMDEVTADSITL 22260
Query: 922 AWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVN 979
+W P G + YI+E R T W + ++ T L +Y FRI A N
Sbjct: 22261 SWGPPKYDGGSSINNYIVEKRDTSTTTW-QIVSATVARTTIKACRLKTGCEYQFRIAAEN 22319
Query: 980 EAGVGEPVELDKGVRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSG 1030
G + + V P PP P LS+R ++ + + G + I
Sbjct: 22320 RYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLER 22379
Query: 1031 SPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYD--I 1088
++W K + I ++K F + +R+ +N G +
Sbjct: 22380 KERNSILWVK-----LNKTPIPQTK----FKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 22430
Query: 1089 HVRVADFP-RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA- 1146
VA P PP N+VTL W YI+ K++ W A+
Sbjct: 22431 ECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASF 22490
Query: 1147 ERVFSNKYTVTGLLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYE 1205
+ + VTGL+ +Y FRV+ARN G SEP +S + +D++ + P
Sbjct: 22491 TNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA-ITARDEVDPPRISMDPKY 22549
Query: 1206 KKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTS 1265
K V G+ + G P PT+ KGD ++ ++ ST
Sbjct: 22550 KDTI-------------VVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 22596
Query: 1266 GVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+L + DSG+Y + +N G+ + + V D+
Sbjct: 22597 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDR 22636
Score = 122 bits (306), Expect = 2e-27
Identities = 200/934 (21%), Positives = 332/934 (35%), Gaps = 131/934 (14%)
Query: 441 ELTSKDVTLRWKK---DGQLLMHGTKYSMNHEGKRA-------------ELIIEDAQLSD 484
+ T K +L W K DG L + G G A + ++ D Q +
Sbjct: 20683 DTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKE 20742
Query: 485 GGEYTVVAMQD---GDPTEYYSTAIVTVE-----------ERLATVKSGMSD--VHAATG 528
+ + A+ D G+P IV E R V++G+S G
Sbjct: 20743 KYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKG 20802
Query: 529 SPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAK 588
PA E W KD + + ++ + + LI P GK+ +
Sbjct: 20803 RPAP----------EVTWTKDNINLKNRANIENTESFTL--LIIPECNRYDTGKFVMTIE 20850
Query: 589 GTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEV 648
+ S F+ P + L IT K T H +P G +
Sbjct: 20851 NPAGKKSGFVNVRVLDTPGPVLNLRPTDIT-KDSVTLHWDLPL----------IDGGSRI 20899
Query: 649 TE---EERVSMERGEDQALLTISNCVREDSGL-------ILLKLKNDHG---SATATLHL 695
T E+R + + A C + +GL + +N++G T +
Sbjct: 20900 TNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPV 20959
Query: 696 SVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVD 755
+ P PP + ++++ S V + W PK +GG +T +++E + G W I V
Sbjct: 20960 KASEAPSPPDS-LNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVK 21018
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQP--QVTDV 813
G + EG+ Y F+++AVNS G S P E+ V P + Q +
Sbjct: 21019 G--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 21076
Query: 814 TKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCT----VDGLLED 869
K I P P + + KKG + + + T + ++ +
Sbjct: 21077 AKAGDNIKVEIPVLGRPKPTVTW-----KKGDQILKQTQRVNFETTATSTILNINECVRS 21131
Query: 870 TEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE- 928
+ + A N G + ++ D PP + + S+ ++ +W P
Sbjct: 21132 DSGPYPLTARNIVGEVGDVI---TIQVHDIPGPP--TGPIKFDEVSSDFVTFSWDPPEND 21186
Query: 929 -GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPV 987
G P S Y++EMR D+ W + I T Y L +Y FR++A N GVG +
Sbjct: 21187 GGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRYGVGPGI 21245
Query: 988 ELDKGVRAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG 1042
V P PP P+ ++A K M + H S P + + +
Sbjct: 21246 TSACIVANYPFKVPGPPGTPQ--VTAVTKDSMTISW------HEPLSDGGSPILGYHVER 21297
Query: 1043 VPTKGRETITKSKNHSQFLINSTKRSDSGV---YRILLQNEFGEARYD------IHVRVA 1093
G T SK I + G+ +R++ +N G+++ + +
Sbjct: 21298 KERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPI 21357
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSN 1152
D P P L + +TVTL W YI+ KRD W A + N
Sbjct: 21358 DPPGKPVPLNITR---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILEN 21414
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHA 1212
++TV+GL Y FRV+A+N G P + +D ++ + K+K K
Sbjct: 21415 EFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVE--APKIKVDVK------ 21466
Query: 1213 PRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLV 1271
K +L+ G+ + G P PT+ K + +K LV
Sbjct: 21467 ------FKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLV 21520
Query: 1272 IPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
T +DSG Y++ N G + + V D+
Sbjct: 21521 NKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDR 21554
Score = 122 bits (305), Expect = 3e-27
Identities = 271/1302 (20%), Positives = 464/1302 (35%), Gaps = 144/1302 (11%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRE-----SGIPIKESAKIFYDSINK 121
P F P V + + + G + W ++ S K ++K F+ SI
Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSI-- 5574
Query: 122 EHVLKLEPLTSDDSDNYKCIASNDHAD--AIYTVSL------------LVTEGQEKMDFK 167
H+L ++ + D Y C A N+ + TV L L E + +
Sbjct: 5575 -HILNVD---TSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQ 5630
Query: 168 KMLKKRAPPAPK--KKQKKVANEKEMLEI--LSKVPKKDFEKVCMEYGFTDFRGLLRKLK 223
++ P + K++++V E E + I + V F K + + +
Sbjct: 5631 ASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKA---EPANAGKYICQIKN 5687
Query: 224 EMKKKVEVEAIRILKP--LEDKETKVDTTVVFDCIMELK---DPNVKMIWIKGTEPLRIQ 278
+ + + + +L+P + +K + TV C +E K P + + W K + L
Sbjct: 5688 DGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLT-- 5745
Query: 279 YSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDE--PLKFLG 332
S K+ L I +V DAG Y+ +VG +A + V D P F
Sbjct: 5746 -SSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTR 5804
Query: 333 EMKPVKVTERQTAVFEIRLSKKEP-NFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDA 391
+K + + E +++ P + W ++ KY+ T S++ T L D+
Sbjct: 5805 RLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDS 5864
Query: 392 RLSDSGEFSAEAGNLVQ----KAQLTIDRIPIKFVSNLKNVRVKERSRACLECELT-SKD 446
SD G ++ A N+ +A LT+ P FV + + V + +
Sbjct: 5865 --SDMGNYTCVAANVAGSDECRAVLTVQEPP-SFVKEPEPLEVLPGKNVTFTSVIRGTPP 5921
Query: 447 VTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAI 506
+ W + + L+ G + ++ E AEL + + +S GEYT V + T
Sbjct: 5922 FKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQAS--CTTR 5979
Query: 507 VTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQG 565
+ V+E A +K +SD G L + W KDG IT IV
Sbjct: 5980 LFVKEPAAFLKR-LSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTE 6038
Query: 566 AVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTA 625
L + G+Y+ + E+ V A T++P + VG +
Sbjct: 6039 KTCILEILNSTKRDAGQYSCEIEN-EAGRDVCGALVSTLEPPYF-VTELEPLEAAVGDSV 6096
Query: 626 HIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKND 685
++ G P V+WYK ++ + A L + DSG K +N
Sbjct: 6097 SLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENS 6156
Query: 686 HGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGK 745
G+A++ + +R PP + ++ + + NG P+ +
Sbjct: 6157 IGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPI-----------Q 6205
Query: 746 KSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEG-----VSDPLETEE----VFAG 796
W + G + N T+ V+ + ++ G S+PL T + A
Sbjct: 6206 VCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAR 6265
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
P + P F +P DV + D V G R W NK+
Sbjct: 6266 EPKKSPFFDIKPVSIDVIA--------GESADFECHVTGAQPMRIT-----WSKDNKEIR 6312
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPV-------KPPGLVQDL 909
G T+ + +T + R++ V K GQ + +++ V KD +PP V+ L
Sbjct: 6313 PGGNYTIT-CVGNTPH-LRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKL 6370
Query: 910 HVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKE-WSKCTKIPISGTCYTVGGLIER 968
S + S+ G P + E W S T+
Sbjct: 6371 EASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAE 6430
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAF 1028
+ A N GVG+ PP K LK G+ + +
Sbjct: 6431 DSGDYICEAHN--GVGDASCSTALTVKAPPVFTQKPSPVGALK-------GSDVILQCEI 6481
Query: 1029 SGSPPPDVIWQKDGVPTKGRETITKSKNH--SQFLINSTKRSDSGVYRILLQNEFGEARY 1086
SG+PP +V+W KD + + + H + I + + SD G Y NE G
Sbjct: 6482 SGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTC 6541
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA 1146
V+ F PP R +++ +T TL + + E I+ + W
Sbjct: 6542 SCSVK---FKEPP---RFVKKLSDTSTL-------IGDAVELRAIVEGFQPISVVWLKDR 6588
Query: 1147 ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD--TWLINKDQIQDLSAKLKPY 1204
V R + +A ++G E +S + N +++ SA L
Sbjct: 6589 GEVIRESENT------RISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVL 6642
Query: 1205 EKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNST 1264
E R + +P TV G + C G P + +K ++A+SK
Sbjct: 6643 EPA------RIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFI 6696
Query: 1265 SGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKD 1306
+ V +L IP + D G YS V+N +GK S+CT++V+ D
Sbjct: 6697 NKVASLKIPCAEMSDKGLYSFEVKNSVGK--SNCTVSVHVSD 6736
Score = 121 bits (303), Expect = 5e-27
Identities = 146/660 (22%), Positives = 265/660 (40%), Gaps = 56/660 (8%)
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLE 128
F ++ Q V A E D + W ++ G+ + E K S K H L +
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKD-GMEVHEGDKYRMHSDRKVHFLSIL 2234
Query: 129 PLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANE 188
+ + D+++Y C+ D + + T + L+ EG ++F K L+ P + +
Sbjct: 2235 TIDTSDAEDYSCVLVED--ENVKTTAKLIVEG-AVVEFVKELQDIEVPESYSGELECIVS 2291
Query: 189 KEMLEILSKVPKKDFE-KVCMEYGFTDFRG--------------------LLRKLKEMKK 227
E +E K D E K +Y T RG + K K
Sbjct: 2292 PENIE--GKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2349
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K++ I IL+ L D++ V + + L+ +V+ +W+K + ++ + K
Sbjct: 2350 KMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE--SVEGVWMKDGQEVQPSDRVHIVIDK 2407
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
Q +ML+I ++ DAG YS ++ +S V + + +K V V E AV
Sbjct: 2408 Q---SHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVL 2464
Query: 348 EIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
E ++S + V W N +++K DD+ + V G L I SD G + G +
Sbjct: 2465 ECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK--GTKQRLVINRTHASDEGPYKLIVGRV 2522
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
L++++ IK + L+++ E E EL+ + + W + + +KY +
Sbjct: 2523 ETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKI 2580
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
GK +L + + D G+YT A E ++ +TV + ++D A
Sbjct: 2581 EAHGKIYKLTVLNMMKDDEGKYTFYA------GENMTSGKLTVAG--GAISKPLTDQTVA 2632
Query: 527 TGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A C V N + +G WL+DGK + ++ G +LI + + G+YT+
Sbjct: 2633 ESQEAVFECEVANPDS-KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTY 2691
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+ +++ A + + +V +TV A V + V W K+G
Sbjct: 2692 KVATSKTSAKLKV-------EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNG 2744
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
+ + E+ ++ L I NC D + +L A+A LH+ + K P+
Sbjct: 2745 VVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL--GRLGASARLHVETVKIIKKPK 2802
Score = 121 bits (303), Expect = 5e-27
Identities = 150/654 (22%), Positives = 261/654 (39%), Gaps = 83/654 (12%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P G+ E ++++ S V + W PK +GG + + VE + W++ ++
Sbjct: 19189 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 19248
Query: 761 --FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE---VFAGNPIEPPGFASQPQVTDVTK 815
++ +EE YQFR +A + +S P E + + A N + + K
Sbjct: 19249 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVK 19308
Query: 816 EAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN--KDPIQGTKCTVD--GLLEDTE 871
+ +A P + + KK L P K +Q CT++ +
Sbjct: 19309 AGTNVCLDATVFGKPMPTVSW-----KKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 19363
Query: 872 YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--G 929
++ + A N +G S+ + + PG + ++ + L+W P E G
Sbjct: 19364 GDYTITAENSSGS------KSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGG 19417
Query: 930 DPPSGYILEMRAEDTKEWSKCTK-IPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE 988
+ YI++ R W++ + +PI T +V LIE +Y FRI A N+ GVG+PV
Sbjct: 19418 SEITNYIVDKRETSRPNWAQVSATVPI--TSCSVEKLIEGHEYQFRICAENKYGVGDPVF 19475
Query: 989 LDKGVRAMPPPAAPKFD---LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPT 1045
+ + P + D +S K HM V S PP D G P
Sbjct: 19476 TEPAIAKNPYDPPGRCDPPVISNITKDHMTV------------SWKPPAD----DGGSPI 19519
Query: 1046 KG-----RET--ITKSKNHSQFLINSTKRSDSGV-------YRILLQNEFG-----EARY 1086
G RET + +K + + +I T ++ +G+ +R+ N+ G +A
Sbjct: 19520 TGYLLEKRETQAVNWTKVNRKPIIERTLKA-TGLQEGTEYEFRVTAINKAGPGKPSDASK 19578
Query: 1087 DIHVRVADFPR-PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTA 1145
+ R +P PP ++++ ++V+L+W Y++ + A + W
Sbjct: 19579 AAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRC 19638
Query: 1146 --AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203
+ + ++ VTGL+ +Y FRV A N+IG S+P D D K +D+ + P
Sbjct: 19639 NLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPD-----KHYPKDIL--IPP 19691
Query: 1204 YEKKDWRHAPRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
+ D L+ +LR G + G P P +T K +VN+
Sbjct: 19692 EGELD--------ADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK 19743
Query: 1263 STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
ST L D+G Y + +EN GK + + V D V ++ E
Sbjct: 19744 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKE 19797
Score = 121 bits (303), Expect = 5e-27
Identities = 140/627 (22%), Positives = 244/627 (38%), Gaps = 83/627 (13%)
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
V + W P +GG +T+++VER+ G+++W G K ++++E +FR+
Sbjct: 27479 VILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGI--SKTCEIEVSQLKEQSVLEFRVF 27536
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTIT------WNAPTQDGGA 831
A N +G+SDP+ + I P + ++D+ VT+ P +
Sbjct: 27537 AKNEKGLSDPVTIGPITVKELIITP----EVDLSDIPGAQVTVRIGHNVHLELPYKGKPK 27592
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
P + ++ + + +V +K + T ++ ++ ++ VI N + +VP
Sbjct: 27593 PSISWLKDGLPLKESEFVRFSKTENKIT-LSIKNAKKEHGGKYTVILDNAVC--RIAVPI 27649
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSK 949
+ + P KP G ++ + S+ L+W P + G + Y +E R W K
Sbjct: 27650 TVITLGPPSKPKGPIR---FDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW-K 27705
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEP-----VELDKGVRAMPPPAAPKF 1004
++ T + V L++ +Y FR+RA N GV +P + R PP P
Sbjct: 27706 MVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVI 27765
Query: 1005 DLSARLKSHMVVRAGTALCIHA-AFSGSPPP-----------DVIWQKDGV-PTKGRETI 1051
+ V G +L A + G ++WQK P GRE
Sbjct: 27766 --------YNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGRE-- 27815
Query: 1052 TKSKNHSQFLINSTKRSDSGVYRILLQNEFG------EARYDIHVRVADFPRPPTNLRLF 1105
+ +R+ +N G +++ + V D P P + +
Sbjct: 27816 --------YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVT 27867
Query: 1106 EEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGR 1163
E T+TL WN P +++ G Y I KR + V +YTVTGL PG
Sbjct: 27868 RE---TITLKWN--PPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGD 27922
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHT 1223
+Y FR++ARN +G P ++ +D+ + P + P + L
Sbjct: 27923 RYEFRIIARNAVGTISPPSQSSGIIMTRDE------NVPPIVE----FGPEYFDGL---I 27969
Query: 1224 VLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDY 1283
+ G+ + G P P VT +K V I G +L + T G Y
Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 28029
Query: 1284 SVLVENELGKDRSSCTLTVYDKDDKSV 1310
+V +N G ++ + V D K V
Sbjct: 28030 TVEAKNASGSAKAEIKVKVQDTPGKVV 28056
Score = 120 bits (302), Expect = 7e-27
Identities = 163/681 (23%), Positives = 272/681 (39%), Gaps = 74/681 (10%)
Query: 361 KFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIK 420
+ N EL R + + +G + +IK A + GE A +++ K L + +
Sbjct: 17852 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 17911
Query: 421 FVS-NLKNVRVKERSRACLECE-LTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIE 478
++ VRV + R + D+T W K+G++L+ + + + R EL I+
Sbjct: 17912 VTCRDVITVRVGQTIRILARVKGRPEPDIT--WTKEGKVLVREKRVDLIQDLPRVELQIK 17969
Query: 479 DAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLN 538
+A +D G+Y + A + +AIV V +R G T E C +
Sbjct: 17970 EAVRADHGKYIISAKNSSGHAQ--GSAIVNVLDR-----PGPCQNLKVTNVTKENCTISW 18022
Query: 539 DEKVEGVWLKDGKEITDL---------PGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKG 589
+ ++ G EIT+ G IV +LI ++ +E Y FR
Sbjct: 18023 ENPLD----NGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNE--YYFRV-C 18075
Query: 590 TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYK---DGM 646
E++ V PTI+ LA + I + G ++ + +GK + W + DG
Sbjct: 18076 AENKVGV----GPTIETKT-PILAINPID-RPGEPENLHIADKGKTFVYLKWRRPDYDGG 18129
Query: 647 EVTEEERVSME-RGED-----------QALLTISNCVREDSGLILLKLKNDHGSATATLH 694
V +G D + + CV ++ KN+ G +
Sbjct: 18130 SPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKT 18189
Query: 695 LSVL---DRPKPPQGRVEFLELSGSCV-----HMKWKAPKDNGGRPVTQFIVERRA--VG 744
V+ D KP V L+LSG ++ +A P + ++ A +
Sbjct: 18190 EEVVVKEDLQKP----VLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 18245
Query: 745 KKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGF 804
+ +KI + + FS K + ++ + A N+ G T N ++ PG
Sbjct: 18246 RSPRVKI-DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATV-----NVLDKPGP 18299
Query: 805 ASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI-QGTKCTV 863
++ DV+ + T+ W+ P DGG + YI+E+ + +W + + GT TV
Sbjct: 18300 VRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGT--TV 18357
Query: 864 DGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAW 923
L+E EY FRV A NK G G P+ S V+AK PG V+ S +++ W
Sbjct: 18358 TRLIEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVW 18416
Query: 924 REPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEA 981
P G +GY LE + + + W K I V L+ +Y FR++A NE
Sbjct: 18417 NPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEI 18476
Query: 982 GVGEPVELDKGVRAMPPPAAP 1002
G+GEP + V A P P
Sbjct: 18477 GIGEPSLPSRPVVAKDPIEPP 18497
Score = 120 bits (301), Expect = 9e-27
Identities = 275/1316 (20%), Positives = 466/1316 (35%), Gaps = 160/1316 (12%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P F++ +P G A+ + V G ISW ++ I+ S K S L+
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKK-QIRSSKKYRLFSQKSLVCLE 3889
Query: 127 LEPLTSDDSDNYKCIASNDHADA--------------IYTVSLLVTEGQEKMDFKKMLKK 172
+ S D Y+C+ +N+ + V L+ G + + + ++
Sbjct: 3890 IFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRG 3949
Query: 173 RAP-PAPKKKQKKVANE--KEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMK--K 227
P K ++V E K + + V V + +G G L E +
Sbjct: 3950 SEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFG-----GKYTCLAENEAGS 4004
Query: 228 KVEVEAIRILKPLE--DKETKVDTTVVFDCIMELK---DPNVKMIWIKGTEPLRIQYSLG 282
+ V + + +P + ++ + T +E P +K W K PL +
Sbjct: 4005 QTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPL---VASK 4061
Query: 283 KYDVKQMGTKYMLVISNVNMNDAGIY----SLSVGDKRMSAELTVLDEPLK--FLGEMKP 336
KY + L + ++D+G Y S VG TVLD + F ++
Sbjct: 4062 KYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRN 4121
Query: 337 VKVTERQTAVFEIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSD 395
V T + +++ P V W +GKE+ D+Y I E T +L+I ++D
Sbjct: 4122 VDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEG--TASLEIIRVDMND 4179
Query: 396 SGEFSAEAGNLV---QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELT-SKDVTLRW 451
+G F+ A N V + I + P FV+ + V S CL+ S +T+RW
Sbjct: 4180 AGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRW 4239
Query: 452 KKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEE 511
K + L+ G + E + L + + SD G YT E +A + V+E
Sbjct: 4240 FKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVE--CSANLFVKE 4297
Query: 512 RLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLP--GMQIVKQGAVH 568
V+ G +L C V ++ W + +EI + M V+ AV
Sbjct: 4298 PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVL 4357
Query: 569 KLIFPSMGPEHEGKYTFRAK---GTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTA 625
+L +G E G+Y A+ G++ +S+ I + S I V +
Sbjct: 4358 RL--TDVGIEDSGEYMCEAQNEAGSDHCSSIVI-----VKESPYFTKEFKPIEVLKEYDV 4410
Query: 626 HIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKND 685
+ G P ++TW+KD + + + L I V D+G ++ N+
Sbjct: 4411 MLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNE 4470
Query: 686 HGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGK 745
GS+ + +++ + P ++ +E + S GG Q ++
Sbjct: 4471 VGSSICSARVTL----REPPSFIKKIESTSSL----------RGGTAAFQATLKGSLPIT 4516
Query: 746 KSWIK----IGEVDGKVTNFSTN-------KVEEGKAYQFRILAVNSEGVSDPLETEEVF 794
+W+K I E D F N +E ++ A N G+
Sbjct: 4517 VTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQ--------- 4567
Query: 795 AGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKD 854
S + +T+EAV+I G L K+ + W ++
Sbjct: 4568 -----RCSALLSVKEPATITEEAVSI----DVTQGDPATLQVKFSGTKEITAKWFKDGQE 4618
Query: 855 PIQGTKCTVDGLLEDTEYEFRVIAVNKAGPG------QPSVPSSSVVAK----DPVKPPG 904
G+K + + DT ++I+ K G Q V SS A+ D + PP
Sbjct: 4619 LTLGSKYKIS--VTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPS 4676
Query: 905 LVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPIS---GTCY- 960
+ L DS S A P I +D +E S K S T +
Sbjct: 4677 FTKKLKKMDSIKGSFIDLECIVAGSHP----ISIQWFKDDQEISASEKYKFSFHDNTAFL 4732
Query: 961 TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGT 1020
+ L + A N+AG + + PP V T
Sbjct: 4733 EISQLEGTDSGTYTCSATNKAGHN---QCSGHLTVKEPP------YFVEKPQSQDVNPNT 4783
Query: 1021 ALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
+ + A G+ P + W KD + + ++ K + + + K +DSG Y L
Sbjct: 4784 RVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLS 4843
Query: 1079 NEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDAS 1138
N+ G A + V + P+ F + P+ V + N E I
Sbjct: 4844 NDVGTATSKATLFVKEPPQ-------FIKKPSPVLVLRNGQSTTFE-----CQITGTPKI 4891
Query: 1139 TATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLS 1198
+WY + + + + G + AR E + ++R N S
Sbjct: 4892 RVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEAR-----NDAGTASCS 4946
Query: 1199 AKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSK 1258
+LK E P F+ LKP V++ D + C G P VT K + I ++ K
Sbjct: 4947 IELKVKE------PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKK 5000
Query: 1259 FWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASI 1314
+ V L I C D+G+Y +V NE G SC+ V K+ S + I
Sbjct: 5001 YTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGS--CSCSTRVALKEPPSFIKKI 5054
Score = 119 bits (297), Expect = 3e-26
Identities = 231/1056 (21%), Positives = 389/1056 (36%), Gaps = 124/1056 (11%)
Query: 294 MLVISNVNMNDAGIYSLSVGDKR---MSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIR 350
+L I N DAG YS + ++ + L EP F+ E++P++ + + +
Sbjct: 6042 ILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQ 6101
Query: 351 LS-KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQK 409
++ E W +L+ +Y + + TL ++DSGE++ +A N +
Sbjct: 6102 VAGTPEITVSWYKGDTKLRPTPEYRTYFTNN--VATLVFNKVNINDSGEYTCKAENSIGT 6159
Query: 410 AQL-TIDRI-----PIKFVSNLKNVRVKERSRACLECELT-SKDVTLRWKKDGQLLMHGT 462
A T+ RI P F LK++ L C L S + + W +DG LL
Sbjct: 6160 ASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDE 6219
Query: 463 KYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLAT----VKS 518
+ A L I LS G+Y+ A S+A +T E + +K
Sbjct: 6220 NLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTAS--SSARLTAREPKKSPFFDIKP 6277
Query: 519 GMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPE 578
DV A + E C V + + W KD KEI I G L +G
Sbjct: 6278 VSIDVIAGESADFE-CHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKG 6336
Query: 579 HEGKYTFRAKGTESE----ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGK 634
G+YT +A + A + + +PP ++ L A + K G + ++ G
Sbjct: 6337 DSGQYTCQATNDVGKDMCSAQLSVKEPPKF----VKKLEASKVA-KQGESIQLECKISGS 6391
Query: 635 PLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLH 694
P KV+W+++ E+ E + +M ALLTI+ EDSG + + N G A+ +
Sbjct: 6392 PEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTA 6451
Query: 695 LSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQ--FIVERRAVGKKSWIKIG 752
L+V P Q L GS V ++ + G P + ++ +R+ V KI
Sbjct: 6452 LTVKAPPVFTQKPSPVGALKGSDVILQCEI----SGTPPFEVVWVKDRKQVRNSKKFKIT 6507
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTD 812
T+ +E ++ A N G SD F EPP F + T
Sbjct: 6508 SKHFD-TSLHILNLEASDVGEYHCKATNEVG-SDTCSCSVKFK----EPPRFVKKLSDTS 6561
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
T G A L IVE + S +W+ + I+ + E+T
Sbjct: 6562 -------------TLIGDAVELRAIVEGFQPISVVWLKDRGEVIRES--------ENTRI 6600
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPP 932
F + + G P +S G+ + V + + EP
Sbjct: 6601 SF-IDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTG 6659
Query: 933 SGYILEMRAEDTKE----WSKCTK-------------IPISGTCYTVGGLIERQKYFFRI 975
+ + LE T E W K + ++ + ++ Y F +
Sbjct: 6660 NPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEV 6719
Query: 976 RAVNEAGVGE-PVELDKGVRAMPPPAAPKF-DLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
+ N G V + R +PP K D++A L G ++ + SGS P
Sbjct: 6720 K--NSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAIL--------GASVVLECRVSGSAP 6769
Query: 1034 PDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091
V W +DG + + + + S+N ++ + SD+G+Y + N G D
Sbjct: 6770 ISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGS---DECSA 6826
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFS 1151
V PP+ FE+ P++V + S +I W+ +
Sbjct: 6827 VLTVQEPPS----FEQTPDSVEVLPGMSLTFTS------VIRGTPPFKVKWFKGSRE--- 6873
Query: 1152 NKYTVTGLLPGRKYYFRV---VARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKD 1208
L+PG + V E+ + +PL+S D + + S + K+
Sbjct: 6874 -------LVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKE- 6925
Query: 1209 WRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVC 1268
FV L +V G + + G P +V+ K + I+ + + T
Sbjct: 6926 ---PATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKST 6982
Query: 1269 TLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
L I T++D YS L+ENE G+D ++V +
Sbjct: 6983 ILEILESTIEDYAQYSCLIENEAGQDICEALVSVLE 7018
Score = 117 bits (294), Expect = 6e-26
Identities = 148/628 (23%), Positives = 233/628 (37%), Gaps = 87/628 (13%)
Query: 713 LSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAY 772
+S S + WK P +GG + ++V+ K W ++ + +S + EGK Y
Sbjct: 19895 VSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRV--MKSLSLQYSAKDLTEGKEY 19951
Query: 773 QFRILAVNSEGVSDPLETEEVFAGNPIEPP-GFASQPQVTDVTKEAVTITWNAPTQDGGA 831
FR+ A N G P E V + + P P + + KE P + A
Sbjct: 19952 TFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPA 20011
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
P + + ++ V V + T D D ++ + N AG + ++ S
Sbjct: 20012 PSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAG-KYTITLKNVAGTKEGTI-S 20069
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSK 949
VV K P P G ++ + + +++L W P + G + YILE R +W
Sbjct: 20070 IKVVGK-PGIPTGPIK---FDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 20125
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSAR 1009
C + T + V L E +Y FR+ A N+ GVGE G+++ P A FD+
Sbjct: 20126 CASA-VQKTTFRVTRLHEGMEYTFRVSAENKYGVGE------GLKSEPIVARHPFDVP-- 20176
Query: 1010 LKSHMVVRAGTALCIHAAFSGSPPPDVI----------W----QKDGVPTKGRETITKSK 1055
PPP+++ W + G P G K +
Sbjct: 20177 -------------------DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKER 20217
Query: 1056 NH-------------SQFLINSTKRSDSGVYRILLQNEFGEARYDIH---VRVADFPRPP 1099
N F + +R++ N G + + V D PP
Sbjct: 20218 NSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 20277
Query: 1100 TNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAE-RVFSNKYTVTG 1158
+ N+VTL W YI+ KRD + +W A V +TVT
Sbjct: 20278 GKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTD 20337
Query: 1159 LLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT 1217
L+ G KY FR+ A+N G S P +S +T +I KD+ + + L P K
Sbjct: 20338 LVEGGKYEFRIRAKNTAGAISAPSESTET-IICKDEYEAPTIVLDPTIKDGL-------- 20388
Query: 1218 PLKPHTVLRGQDCTMTC-AFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
T+ G + + LG P P + K +I + ST L I T
Sbjct: 20389 -----TIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 20443
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYD 1304
KD+G+Y++ N G +TV D
Sbjct: 20444 RKDAGEYTITATNPFGTKVEHVKVTVLD 20471
Score = 112 bits (281), Expect = 2e-24
Identities = 156/679 (22%), Positives = 263/679 (38%), Gaps = 103/679 (15%)
Query: 52 SLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISW-KRESGIPIKE 110
S VT N P P+ +++ QPVT G A F A + G +P ISW K E +
Sbjct: 3227 SSVTLYVNAP---EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGF 3283
Query: 111 SAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKML 170
K +D +E+ L L +D+ Y C A ND+ A + SL V E E + + +
Sbjct: 3284 KCKFLHD--GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEM 3340
Query: 171 KKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVE 230
P Q V +E + +V D K+ K +
Sbjct: 3341 PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-----------------KVSWYSKDKK 3383
Query: 231 VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
++ R + + ++T Q + + + G
Sbjct: 3384 IKPSRFFRMTQFEDT-------------------------------YQLEIAEAYPEDEG 3412
Query: 291 TKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPL--KFLGEMKPVKVTERQTAVFE 348
T Y V SN + +LS + A ++L E + + EMK V +R+ E
Sbjct: 3413 T-YTFVASNAVGQVSSTANLS-----LEAPESILHERIEQEIEMEMKAAPVIKRKIEPLE 3466
Query: 349 IRLS---------KKEPN--FVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSG 397
+ L + PN F W G+E+ DK I S+ +L+I ++ D G
Sbjct: 3467 VALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSK--YISSLEILRTQVVDCG 3524
Query: 398 EFSAEA----GNLVQKAQLTI-DRIPIKFVSNLKNVRVKERSRACLECELTSKDV-TLRW 451
E++ +A G++ A LT+ + P F+S K++ A C +T V W
Sbjct: 3525 EYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIW 3584
Query: 452 KKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEE 511
+KDG L + ++ + L + + + D G Y+ A + I+ +
Sbjct: 3585 QKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKP 3644
Query: 512 RLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKL 570
+ V +A L C V D KV W KDG+++ +I + + L
Sbjct: 3645 HFI---KELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATL 3701
Query: 571 IFPSMGPEHEGKYTFRAK----GTESEASVFIADPPT----IDPSVLEALAAHAITVKVG 622
P + G Y A + A+V + +PP+ +DPS L + G
Sbjct: 3702 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYL---------MLPG 3752
Query: 623 HTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKL 682
+A + +G P+ +VTW+K+ E++E V M +A+L I++ EDSG +
Sbjct: 3753 ESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEA 3812
Query: 683 KNDHGSATATLHLSVLDRP 701
ND GS + + + + + P
Sbjct: 3813 VNDVGSDSCSTEIVIKEPP 3831
Score = 112 bits (280), Expect = 2e-24
Identities = 159/745 (21%), Positives = 291/745 (39%), Gaps = 74/745 (9%)
Query: 5 HSRQMLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSS--SIVEFFSLVTRSSNIPA 62
H++ M+F ++ + VGE + +S ++ LV ++ +P
Sbjct: 7057 HTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLP- 7115
Query: 63 GDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKE 122
P F K + V G F R+ G+ +SW ++ G+ +K+ A + ++
Sbjct: 7116 ----PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKD-GVLLKDDANLQTSFVHNV 7170
Query: 123 HVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQ-----------------EKMD 165
L++ Y C ASN A + L+++E + E
Sbjct: 7171 ATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGT 7230
Query: 166 FKKMLKKRAP-------------PAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGF 212
FK + AP P K V N + + KV K D + +
Sbjct: 7231 FKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVL--KVGKGDAGQ------Y 7282
Query: 213 TDFRGLLRKLKEMKKKVEV-EAIRILKPLE-DKETKVDTTVVFDCIMELKDPNVKMIWIK 270
T + + ++ V E R +K LE + K D ++C + P +K++W K
Sbjct: 7283 TCYASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIG-GSPEIKVLWYK 7341
Query: 271 GTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDE 326
+ IQ S K+ + + + +L + N+++ D+G Y+ + G S L V +
Sbjct: 7342 --DETEIQES-SKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEP 7398
Query: 327 PLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHT 385
P+ F + P++ + E L P V W + +EL+ KY+I +SE+ LT +
Sbjct: 7399 PI-FRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI-MSENFLT-S 7455
Query: 386 LKIKDARLSDSGEFSAEAGNLVQKAQLTID---RIPIKFVSNLKNVRVKERSRACLECEL 442
+ I + +D GE+ +A N V + P +FV L ++ L+ +
Sbjct: 7456 IHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTI 7515
Query: 443 T-SKDVTLRWKKD-GQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTE 500
++ +++ W KD G+++ +++ A L + ++ G+YT D E
Sbjct: 7516 EGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQE 7575
Query: 501 YYSTAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGM 559
++T V AT+ + TG L C V ++ W KDGKE+T
Sbjct: 7576 CFATLSVL---EPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKY 7632
Query: 560 QIVKQGAVHKLIFPSMGPEHEGKYTFRAK---GTESEASVFIADPPTIDPSVLEALAAHA 616
+I V L ++ P G Y+F + G +S + T+ PS L
Sbjct: 7633 KISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKL--KE 7690
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
G + ++ G P V+W+ +G E++ + ++ LT++ DSG
Sbjct: 7691 TNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSG 7750
Query: 677 LILLKLKNDHGSATATLHLSVLDRP 701
N GS + L+V + P
Sbjct: 7751 DYTCIATNMAGSDECSAPLTVREPP 7775
Score = 109 bits (273), Expect = 2e-23
Identities = 145/639 (22%), Positives = 241/639 (37%), Gaps = 71/639 (11%)
Query: 695 LSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEV 754
++V +RP+ +E E++ + V + W PK +GG + +++E R +G + + K+
Sbjct: 16714 ITVPERPED----LEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTND 16769
Query: 755 DGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVT 814
+ ++ ++EG Y++R+ AVN G P F PI + P +
Sbjct: 16770 NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPS-----FCTKPITCKDELAPPTLHLDF 16824
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE- 873
++ +TI + G A L + K W D ++ + + E
Sbjct: 16825 RDKLTI------RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEK 16878
Query: 874 ----------FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAW 923
+ V+ N G + + V D PP V + + + + ++W
Sbjct: 16879 IKAKRSDSGKYCVVVENSTGSRKGFCQVNVV---DRPGPP--VGPVSFDEVTKDYMVISW 16933
Query: 924 REPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEA 981
+ P + G + YI+E + W T TC V L+E + Y FRI A N
Sbjct: 16934 KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTC-KVSKLLEGKDYIFRIHAENLY 16992
Query: 982 GVGEPVELD--KGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQ 1039
G+ +P+ D K P AP + + + G P + I +
Sbjct: 16993 GISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNK----PHDGGKPITNYILE 17048
Query: 1040 KDGVPTKGRETITKSKNH--SQFLINSTKRSDSGVYRILLQNEFG------EARYDIHVR 1091
K +K +TK H ++F + +R+ +NE G ++
Sbjct: 17049 KRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKD 17108
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTA---A 1146
P PP N + N+V LTW P + G YI+ + W A
Sbjct: 17109 PIAKPSPPVNPEAIDTTCNSVDLTWQ--PPRHDGGSKILGYIVEYQKVGDEEWRRANHTP 17166
Query: 1147 ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEK 1206
E KY VTGL G+ Y FRV+A N G+S+P + L+ KD+++ L
Sbjct: 17167 ESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLV-KDRLEPPELILD---- 17221
Query: 1207 KDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG 1266
+ + G ++ G P P VT K D + A +K + T
Sbjct: 17222 ---------ANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD--APTKARIDVTPV 17270
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
L I +D G YS+ VEN G S + V DK
Sbjct: 17271 GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 17309
Score = 107 bits (268), Expect = 6e-23
Identities = 144/617 (23%), Positives = 249/617 (40%), Gaps = 55/617 (8%)
Query: 217 GLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLR 276
G K K VE +R +K LE++ T V ++ K+ +V +W K +
Sbjct: 11195 GNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDV--VWRKDGKI-- 11250
Query: 277 IQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV---GDKRMSAELTVLDEPLKFLGE 333
+ G+ +G L I++ + DAG Y+++V + S+ + V++ +L
Sbjct: 11251 VVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWL-- 11308
Query: 334 MKPVK---VTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKD 390
+KP++ V + TA+F ++K PN W E+ + + + DG LKIK+
Sbjct: 11309 VKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKN 11368
Query: 391 ARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLR 450
A D E++ E A+LT+ ++ + +++V + E+ A + E++ D+ +
Sbjct: 11369 AMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQ 11428
Query: 451 WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVE 510
WK G+LL + EG + L + +L GE A+ +TAI+TV+
Sbjct: 11429 WKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQAL------NAITTAILTVK 11482
Query: 511 ERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHK 569
E + DV A CV+ + V +W K I I+ G H
Sbjct: 11483 EIELDFAVPLKDVTVPERRQARFECVLTREANV--IWSKGPDIIKSSDKFDIIADGKKHI 11540
Query: 570 LIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKV 629
L+ + EG YT +G ++ A +F+ S LE TVK G TA
Sbjct: 11541 LVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQ-----TVKEGETATFVC 11595
Query: 630 PFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA 689
+ + V W+K+ ++ V + L + +D I ++K
Sbjct: 11596 ELSHEKM-HVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVK----EL 11650
Query: 690 TATLHLSVLDRPK------PPQGRVEFLELSGSC-----VHMKWKAPKDNGGRPVTQFIV 738
++T L VL+ + VE E++ C V +KW +G V
Sbjct: 11651 SSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKW---FKDGEEIVPSPKY 11707
Query: 739 ERRAVGKKSWIKIGEVDGK-----VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEV 793
+A G + +KI + D K V + T+K + + R++ V PL EV
Sbjct: 11708 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEK-----PLYGVEV 11762
Query: 794 FAGNPIEPPGFASQPQV 810
F G S+P V
Sbjct: 11763 FVGETAHFEIELSEPDV 11779
Score = 107 bits (266), Expect = 1e-22
Identities = 168/748 (22%), Positives = 293/748 (39%), Gaps = 96/748 (12%)
Query: 232 EAIRILKPLEDKETKVDTTVVFDC-IMELKDPNVKMIWIK-GTEPLRIQYSLGKYDVKQM 289
EA I K ++D TK+ C I+ P++K W + G E ++ + KY +
Sbjct: 30531 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSR----KYKMSSD 30584
Query: 290 GTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
G + L + D G+Y+ VG+ S++L + P G P+K
Sbjct: 30585 GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGY--PLKEKYYGAV 30642
Query: 346 VFEIRL-----SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFS 400
+RL + P W F+G++L ++ + + + TH + R + +G++
Sbjct: 30643 GSTLRLHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYK 30701
Query: 401 AEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMH 460
+ N+ +D +++ K +E L + V + WK
Sbjct: 30702 VQLSNVFGTVDAILD-------VEIQDKPDKPTGPIVIEALLKNSAV-ISWKPPAD---D 30750
Query: 461 GTKYSMNH--------EGKRAELIIEDAQLS---------DGGEYTVVAMQD----GDPT 499
G + N+ EG +L+ ++ + G Y V+ Q+ DP
Sbjct: 30751 GGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPL 30810
Query: 500 EYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVL-------NDEKVEGVWLKDGKE 552
E S I+ + K G T + CVV K+ +L+ +E
Sbjct: 30811 EVSSVVII----KSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEK-RE 30865
Query: 553 ITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAK----GTESEASVFI------ADPP 602
+ + + + + +F +Y FR K G ESE S +D P
Sbjct: 30866 KKQNKWISVTTE-EIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVP 30924
Query: 603 TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEE---RVSMERG 659
P E L + V+ A + G P P V WY+ G E+ + R+ +G
Sbjct: 30925 IQAPHFKEEL--RNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKG 30982
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV-----LDRPKPPQGRVEFLELS 714
L+ I++ +D+ + ++ N GS + T L V + PK +G L
Sbjct: 30983 GYHQLI-IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALR 31041
Query: 715 GSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQF 774
G V +K P PV + + + ++ + N VE A +
Sbjct: 31042 GEVVSIK--IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFY 31099
Query: 775 RILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVL 834
+ A N G+ +T E+ + +PP +V+DV++++V +TW P DGG+ +
Sbjct: 31100 VVCAKNRFGIDQ--KTVELDVADVPDPPRGV---KVSDVSRDSVNLTWTEPASDGGSKIT 31154
Query: 835 GYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSV 894
YIVE+ + W+ V + + T+ TV L T Y+FRVIA NK G +PS PS
Sbjct: 31155 NYIVEKCATTAERWLRVGQ--ARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPT 31212
Query: 895 VAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ K+ K + D V ++ S++ A
Sbjct: 31213 ITKED-KTRAMNYDEEVDETREVSMTKA 31239
Score = 99.0 bits (245), Expect = 3e-20
Identities = 146/681 (21%), Positives = 262/681 (38%), Gaps = 70/681 (10%)
Query: 70 VEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEP 129
+EKP+P+T G+ V G + W ++ G + +K INK LK+
Sbjct: 6648 IEKPEPMTVTTGNPFALECVVTGTPELSAKWFKD-GRELSADSKHHITFINKVASLKIPC 6706
Query: 130 LTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANEK 189
D Y N + TVS+ V++ + PP+ +K K V N
Sbjct: 6707 AEMSDKGLYSFEVKNSVGKSNCTVSVHVSD------------RIVPPSFIRKLKDV-NAI 6753
Query: 190 EMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETKVDT 249
++ + + + + F D ++ K E L LE +T + T
Sbjct: 6754 LGASVVLECRVSGSAPISVGW-FQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYT 6812
Query: 250 TVVFD--------CIMELKDP--------NVKMI---------WIKGTEPLRIQYSLGKY 284
V + ++ +++P +V+++ I+GT P ++++ G
Sbjct: 6813 CVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSR 6872
Query: 285 DVKQMGTKYM--------LVISNVNMNDAGIYSLSVGDKRMSAELTV---LDEPLKFLGE 333
++ + + L + V ++G YS V + SA T + EP F+
Sbjct: 6873 ELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKR 6932
Query: 334 MKPVKVTERQTAVFEIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDAR 392
+ V V E + P V W + + + ++ IT++E L+I ++
Sbjct: 6933 LADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTI--LEILEST 6990
Query: 393 LSDSGEFSA----EAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELT-SKDV 447
+ D ++S EAG + +A +++ P F+ L++V A L+C++ + ++
Sbjct: 6991 IEDYAQYSCLIENEAGQDICEALVSVLEPPY-FIEPLEHVEAVIGEPATLQCKVDGTPEI 7049
Query: 448 TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIV 507
+ W K+ L Y M + A L+I SD GEY+ A D S+A++
Sbjct: 7050 RISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKA--DNSVGAVASSAVL 7107
Query: 508 TVEERLAT--VKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQ 564
++ R + DVH G P C + E ++ W KDG + D +Q
Sbjct: 7108 VIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFV 7167
Query: 565 GAVHKLIFPSMGPEHEGKYTFRAK---GTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
V L H G+Y A GT S ++ I + P L ++ + +
Sbjct: 7168 HNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFF--DLKPVSVDLAL 7225
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
G + K G K+TW KD E+ M E+ A LT+ + D+G
Sbjct: 7226 GESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCY 7285
Query: 682 LKNDHGSATATLHLSVLDRPK 702
N G + + L V + P+
Sbjct: 7286 ASNIAGKDSCSAQLGVQEPPR 7306
Score = 98.2 bits (243), Expect = 5e-20
Identities = 145/714 (20%), Positives = 274/714 (38%), Gaps = 108/714 (15%)
Query: 3 TIHSRQMLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPA 62
T+ + L VS EF TT V T K EE +S +V + +T P
Sbjct: 1023 TVSTSCYLAVQVSEEFEKETTAV-----TEKFTTEEKRFVESRDVVMTDTSLTEEQAGPG 1077
Query: 63 GDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA--KIFYDSIN 120
+ P F+ KP EG VF +V GN KPH+ WK+ SG+P+ K+ Y+
Sbjct: 1078 EPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK-SGVPLTTGYRYKVSYNKQT 1136
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK 180
E L + +DD+ Y + N H + + SLL E+ D++ ++K + +
Sbjct: 1137 GECKLVISMTFADDAGEYTIVVRNKHGETSASASLL-----EEADYELLMKSQQEMLYQT 1191
Query: 181 KQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPL 240
+ E ++ E ++EK EY ++ ++KK+ + + + +
Sbjct: 1192 QVTAFVQEPKVGETAPGFVYSEYEK---EYE--------KEQALIRKKMAKDTVVVRTYV 1240
Query: 241 EDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNV 300
ED+E + + ++ +K I+Y + K ++++
Sbjct: 1241 EDQEFHISS---------FEERLIK----------EIEYRIIKTTLEEL----------- 1270
Query: 301 NMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKE-PNFV 359
+ + G ++V A + D +K ++ E F ++S P
Sbjct: 1271 -LEEDGEEKMAVDISESEAVESGFDS------RIKNYRILEGMGVTFHCKMSGYPLPKIA 1323
Query: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQLTID 415
W +GK +K ++Y++ +DG +L+I D G ++A A GN + +L ++
Sbjct: 1324 WYKDGKRIKHGERYQMDFLQDGRA-SLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382
Query: 416 -RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAE 474
P+ + + + R R+ ++ + + + M + S
Sbjct: 1383 PAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMS--------- 1433
Query: 475 LIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH--AATGSPAE 532
A++S G +++ D ++ ERL + V G A
Sbjct: 1434 ----PARMSPGRR-----LEETDESQL---------ERLYKPVFVLKPVSFKCLEGQTAR 1475
Query: 533 LCV-VLNDEKVEGVWLKDGKEIT-DLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
+ V+ E W DG++I D ++K+ LI P G++T A+
Sbjct: 1476 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1535
Query: 591 ESEASVFI-----ADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+S+ + A + P +E L + +K G +KV G P P + W K+
Sbjct: 1536 AGRSSISVILTVEAVEHQVKPMFVEKLKN--VNIKEGSRLEMKVRATGNPNPDIVWLKNS 1593
Query: 646 MEVTEEE--RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
+ + ++ +E + +A L I + V +DS N G T ++V
Sbjct: 1594 DIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647
Score = 95.9 bits (237), Expect = 2e-19
Identities = 152/639 (23%), Positives = 238/639 (37%), Gaps = 111/639 (17%)
Query: 430 VKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
VK + CL+ + K + T+ WKKDG LL M + L + D G+Y
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCV-VLNDEKVEGVW- 546
T+ TA + + AT+K + D G PA + + + ++ W
Sbjct: 19367 TI-------------TAENSSGSKSATIKLKVLD---KPGPPASVKINKMYSDRAMLSWE 19410
Query: 547 --LKDG----------KEITDLPGMQIVKQG------AVHKLIFPSMGPEHEGKYTFRAK 588
L+DG K T P V +V KLI HE ++ A+
Sbjct: 19411 PPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLI-----EGHEYQFRICAE 19465
Query: 589 G---------TESEASVFIADPP-TIDPSVLEALAAHAITVKVGHTAHIK-VPFRGKPLP 637
TE + DPP DP V+ + +TV A P G L
Sbjct: 19466 NKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLE 19525
Query: 638 K-----VTWYKDGMEVTEEERVS----MERGEDQALLTISNCVREDSGLILLKLKNDHGS 688
K V W K + E + E E + +T N K G
Sbjct: 19526 KRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAIN-------------KAGPGK 19572
Query: 689 ATATLHLSVLDRPKPPQGRVEF---LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGK 745
+ + P+ P G F + + S V + W P +GG P+ ++VE +
Sbjct: 19573 PSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS 19632
Query: 746 KSWIKIGEVDG-KVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLET-EEVFAGNPIEPPG 803
+W++ + T F + E YQFR+ AVN G SDP + ++ + + + PP
Sbjct: 19633 DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPE 19692
Query: 804 --FASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
+ + T + + VT+ P + P + + K NL + D
Sbjct: 19693 GELDADLRKTLILRAGVTMRLYVPVKGRPPPKITW----SKPNVNLRDRIGLD------- 19741
Query: 862 TVDGLLEDTEYE--FRVIAVNKAGPGQPSVPSSSVVAKDP-------VKPPGLVQDLHVS 912
++ T+++ R VNK G+ + + K + PG ++ V
Sbjct: 19742 -----IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVK 19796
Query: 913 DSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQK 970
+ S S + W P G P Y+++ R + K WS T S T + V L E +
Sbjct: 19797 EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTT-ECSKTSFRVANLEEGKS 19855
Query: 971 YFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSAR 1009
YFFR+ A NE G+G+P E V+A P P DL R
Sbjct: 19856 YFFRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVR 19893
Score = 93.2 bits (230), Expect = 1e-18
Identities = 145/690 (21%), Positives = 261/690 (37%), Gaps = 111/690 (16%)
Query: 52 SLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKES 111
+L T S I P F + PVT EG+ VQG+ I W + +G IK S
Sbjct: 8331 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLK-AGREIKPS 8389
Query: 112 AKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171
+ + + VL+L + DS +Y C ASN G + K +K
Sbjct: 8390 DRCSFSFASGTAVLELRDVAKADSGDYVCKASN-------------VAGSDTTKSKVTIK 8436
Query: 172 KRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEV 231
+ AP K+ V + E
Sbjct: 8437 DKPAVAPATKKAAVDGRLFFVS------------------------------------EP 8460
Query: 232 EAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGT 291
++IR+++ TT F + DP + W KG R G+ + Q G
Sbjct: 8461 QSIRVVEK---------TTATFIAKVG-GDPIPNVKWTKGK--WRQLNQGGRVFIHQKGD 8508
Query: 292 KYMLVISNVNMNDAGIYSLSVGDKRMSAELTV---LDEPLKFLGEMKPVKVTERQTAVFE 348
+ L I + D+G+Y ++ E V +DE K ++ ++T + +
Sbjct: 8509 EAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILK 8568
Query: 349 IRLSKKEPNFVWKF-NGKELKRDDKYE-----------------ITVSEDGLTHTLKIKD 390
++E + + + K +KY + S++ TH L+I++
Sbjct: 8569 KGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEE 8628
Query: 391 ARLSDSGEFSAEAGNLVQKAQLTIDRI-PIKFVSNLKNVRVKERSRACLECELTSK--DV 447
S+ E E LV Q + + P+ + +++N V + + A E ++ ++
Sbjct: 8629 IERSERDEKEFE--ELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEI 8686
Query: 448 TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIV 507
L W K + L K+ ++ +G R L +++ QL D G Y +V + ++A +
Sbjct: 8687 KLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC------GPHIASAKL 8740
Query: 508 TVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAV 567
TV E + + DV G + + V+ W ++G+ + + + V
Sbjct: 8741 TVIE--PAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKV 8798
Query: 568 HKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHI 627
HKL + E +G+YT + + E+ A + I P ++ + ++ T
Sbjct: 8799 HKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIV---VSEHQSATFEC 8855
Query: 628 KVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGL--ILLKLK-N 684
+V F VTWYK E+TE ++ + +TI N +D G+ ++ +L+
Sbjct: 8856 EVSFDDAI---VTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPR 8912
Query: 685 DHGSATATLHLSV------LDRPKPPQGRV 708
+TA L+L+ L P P RV
Sbjct: 8913 GEARSTAELYLTTKEIKLELKPPDIPDSRV 8942
Score = 92.8 bits (229), Expect = 2e-18
Identities = 110/495 (22%), Positives = 193/495 (38%), Gaps = 34/495 (6%)
Query: 232 EAIRILKPLEDKETKV-DTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
+ I + L+D K DT F+C E +P VK+ W K + + KY +
Sbjct: 2172 QLITFTQELQDVVAKEKDTMATFEC--ETSEPFVKVKWYKDGMEV---HEGDKYRMHSDR 2226
Query: 291 TKYMLVISNVNMNDAGIYS-LSVGDKRM--SAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+ L I ++ +DA YS + V D+ + +A+L V ++F+ E++ ++V E +
Sbjct: 2227 KVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGEL 2286
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E +S + W N ELK + KY IT S G L +KD D GE+S
Sbjct: 2287 ECIVSPENIEGKWYHNDVELKSNGKYTIT-SRRG-RQNLTVKDVTKEDQGEYSFVIDGKK 2344
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
+L + PI + L + +V E LE +++ + V W KDGQ + + +
Sbjct: 2345 TTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIV 2404
Query: 468 HEGKRAELIIEDAQLSDGGEYT----VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
+ + L+IED D G Y+ + + YS ++T + DV
Sbjct: 2405 IDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVIT----------PLKDV 2454
Query: 524 HAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGK 582
+ G+ A L C V + W + ++I +Q + +G +L+ EG
Sbjct: 2455 NVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGP 2514
Query: 583 YTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWY 642
Y E+ ++ + ++ L T +++ G V W
Sbjct: 2515 YKLIVGRVETNCNLSVE-----KIKIIRGLRDLTCTETQNVVFEVELSHSG---IDVLWN 2566
Query: 643 KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPK 702
E+ + +E LT+ N +++D G + S T+ + +P
Sbjct: 2567 FKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAISKPL 2626
Query: 703 PPQGRVEFLELSGSC 717
Q E E C
Sbjct: 2627 TDQTVAESQEAVFEC 2641
Score = 85.9 bits (211), Expect = 2e-16
Identities = 147/715 (20%), Positives = 268/715 (37%), Gaps = 124/715 (17%)
Query: 72 KPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLT 131
KP+ +T EG+ A F G P ++W R+ + + SA+ + + ++ +
Sbjct: 32566 KPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQV-LSTSARHQVTTTKYKSTFEISSVQ 32624
Query: 132 SDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKR--------APPAPKKKQK 183
+ D NY + N +EG+++ +F ++K +PP K +
Sbjct: 32625 ASDEGNYSVVVEN-------------SEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEP 32671
Query: 184 KVANEKEMLEILS-KVPKKDFEKVCMEYGFTDFRGL-LRKLKEMKKKVEVEAIRILKPLE 241
+V + + + K P+ K T+ + K++ + + + LK
Sbjct: 32672 RVKSPEAVKSPKRVKSPEPSHPKAVSP---TETKPTPTEKVQHLPVSAPPKITQFLKAEA 32728
Query: 242 DKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVN 301
KE T VV ++ K+ + W K + L+ + ++ GT Y L I+N+
Sbjct: 32729 SKEIAKLTCVVESSVLRAKE----VTWYKDGKKLK-ENGHFQFHYSADGT-YELKINNLT 32782
Query: 302 MNDAGIYSLSVGDKRMSAE--LTVLDEPLKFLGEM------------------------- 334
+D G Y + + +++ L + + K + E
Sbjct: 32783 ESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP 32842
Query: 335 --------KPVKVTERQ--------TAVFEIRLS-KKEPNFVWKFNGKELKRDDKYEITV 377
KPV VT Q A F ++ + + P +W +GK + + KY++
Sbjct: 32843 KAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL-- 32900
Query: 378 SEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTIDRIP---IKFVSNLKNVRV 430
SED L+I SDSG ++ AG++ +LTI I + VS K +
Sbjct: 32901 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEI 32960
Query: 431 KERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTV 490
+ +A ++ E++ K + K + K ++ E + LI E+ + S
Sbjct: 32961 TPQKKAVVQEEISQKALRSEEIKMSEAKSQ-EKLALKEEASKV-LISEEVKKSAATSLEK 33018
Query: 491 VAMQDGDPTEYYSTAIVTVEERL-ATVKSGMSDVHAATGSPAELCVVLNDEKVEGV-WLK 548
+ + E T+ + E R A +K+ + + G L + N V W+
Sbjct: 33019 SIVHE----EITKTSQASEEVRTHAEIKAFSTQMSINEGQ--RLVLKANIAGATDVKWVL 33072
Query: 549 DGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTE---------------SE 593
+G E+T+ + G+ L EG T +K E S+
Sbjct: 33073 NGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSD 33132
Query: 594 ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEER 653
A FI+ P + + G G+P P++ W+K+ + ++
Sbjct: 33133 APAFISQP-------------RSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN 33179
Query: 654 VSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRV 708
VS+ R + L I N DSG +K KN G +AT L VL + P V
Sbjct: 33180 VSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREV 33234
Score = 83.6 bits (205), Expect = 1e-15
Identities = 80/296 (27%), Positives = 128/296 (43%), Gaps = 15/296 (5%)
Query: 417 IPIKFVSNLKNVRVKER----SRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKR 472
+P+KFV +K++ + E S A EC ++ W KDG + K+ +GK
Sbjct: 11113 VPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKD 11172
Query: 473 AELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAE 532
+L I D QLSD GEYT V ++ G+ + + +V E + VK+ +V G P
Sbjct: 11173 RKLHIIDVQLSDAGEYTCV-LRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 11231
Query: 533 LCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQ--GAVHKLIFPSMGPEHEGKYTFRAKGT 590
L LN E+ + VW KDGK + + PG +IV G + L G YT +
Sbjct: 11232 LSCELNKER-DVVWRKDGKIVVEKPG-RIVPGVIGLMRALTINDADDTDAGTYTVTVENA 11289
Query: 591 ES-EASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVT 649
+ E S + I +++ + VK TA K P + W+K E+
Sbjct: 11290 NNLECSSCVKVVEVIRDWLVKPIRDQ--HVKPKGTAIFACDI-AKDTPNIKWFKGYDEIP 11346
Query: 650 EE--ERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKP 703
E ++ + R + L I N + ED ++++ A TL ++ KP
Sbjct: 11347 AEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKP 11402
Score = 83.6 bits (205), Expect = 1e-15
Identities = 150/648 (23%), Positives = 250/648 (38%), Gaps = 101/648 (15%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
D+P P G +E L +S V ++W+ P+ +GG+ + + VE R G +W K + K
Sbjct: 30429 DKPSQP-GELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKD 30487
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-----EVFAGNPIEPPGFASQPQVTDV 813
F+ + E Y+FR+ A N G+S P T ++ +G E PG + ++ DV
Sbjct: 30488 KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSG---EAPGI--RKEMKDV 30542
Query: 814 TKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC---------TVD 864
T T+ G A L + R W K+ IQ K T+
Sbjct: 30543 T-----------TKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 30591
Query: 865 GLLEDTEYE--FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ E+ E E + IA N+ G + S S ++ P PG + S++ L
Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETS--SKLLLQATPQFHPGYPLKEKYYGAVGSTLRLH 30649
Query: 923 WREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGT---CYTVGGLIERQKYF--FRIRA 977
P + + E I I T + V ++R+ + ++++
Sbjct: 30650 VMYIGRPVPAMTWFHGQKLLQNSE-----NITIENTEHYTHLVMKNVQRKTHAGKYKVQL 30704
Query: 978 VNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV- 1036
N G + + LD ++ P + A LK+ V+ S PP D
Sbjct: 30705 SNVFGTVDAI-LDVEIQDKPDKPTGPIVIEALLKNSAVI------------SWKPPADDG 30751
Query: 1037 -IWQKDGVPTK-----GRETITKSKNHSQF---LINSTKRSDSGVY-RILLQNEFGEAR- 1085
W + V K G E S S ++N T+ ++G Y R+ QN FG +
Sbjct: 30752 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDP 30809
Query: 1086 ---YDIHVRVADFPRP--PTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDAS 1138
+ + + F +P P + ++ + W P + G +Y + KR+
Sbjct: 30810 LEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWK--PPASDGGAKIRNYYLEKREKK 30867
Query: 1139 TATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDL 1197
W + E + ++V L+ G +Y FRV N G+SE W ++
Sbjct: 30868 QNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESE-------W-------SEI 30913
Query: 1198 SAKLKPYEKKDWR-HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITAN 1256
S + P K D AP F L+ V + T+ C G+P+P V Y+ I A+
Sbjct: 30914 SEPITP--KSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIAD 30971
Query: 1257 SKFW--YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
+ G L+I + T D+ Y V N+ G + +L V
Sbjct: 30972 GLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 31019
Score = 77.0 bits (188), Expect = 1e-13
Identities = 74/286 (25%), Positives = 127/286 (44%), Gaps = 17/286 (5%)
Query: 327 PLKFLGEMKPVKVTERQ----TAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGL 382
PLKF+ E+K + +TE + +A+FE +S W +G ++ K+ DG
Sbjct: 11114 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIA--DGK 11171
Query: 383 THTLKIKDARLSDSGEFSA--EAGN--LVQKAQLTIDRIPIKFVSNL-KNVRVKERSRAC 437
L I D +LSD+GE++ GN A+L ++ +P++FV L + V V +
Sbjct: 11172 DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 11231
Query: 438 LECELTSKDVTLRWKKDGQLLMHGT-KYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDG 496
L CEL +K+ + W+KDG++++ + G L I DA +D G YT V +++
Sbjct: 11232 LSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYT-VTVENA 11289
Query: 497 DPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDL 556
+ E S+ + VE + + D H A + + W K EI
Sbjct: 11290 NNLE-CSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAE 11348
Query: 557 PG--MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIAD 600
P +I++ G L + PE +Y +G A + + +
Sbjct: 11349 PNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGE 11394
Score = 75.5 bits (184), Expect = 3e-13
Identities = 142/714 (19%), Positives = 258/714 (36%), Gaps = 116/714 (16%)
Query: 14 VSMEFSSSTTHVQTFSQTTKIVGEEVVR---RKSSSIVEFFSLVTRSSNIPAGDSV---P 67
+S E +S T++Q Q K + E+V + K S S VTR + A + + P
Sbjct: 32793 ISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKP 32852
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
V Q T A F + G +P W ++ G I + K
Sbjct: 32853 VIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKD-GKAITQGGKY------------- 32898
Query: 128 EPLTSDDSDNYKCIASNDHADA-IYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
L+ D + I D +D+ +YT ++ + G K +K + +KV+
Sbjct: 32899 -KLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA----IKDTEAQKVS 32953
Query: 187 NEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETK 246
+K ++ KK V E I K L +E
Sbjct: 32954 TQKTS-----------------------------EITPQKKAVVQEEIS-QKALRSEE-- 32981
Query: 247 VDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAG 306
+KM K E L ++ K + + K + ++ +
Sbjct: 32982 -----------------IKMSEAKSQEKLALKEEASKVLISEEVKKS----AATSLEKSI 33020
Query: 307 IYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKE 366
++ + S E+ E F +M + E Q V + ++ + W NG E
Sbjct: 33021 VHEEITKTSQASEEVRTHAEIKAFSTQMS---INEGQRLVLKANIAGAT-DVKWVLNGVE 33076
Query: 367 LKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTIDRI---PI 419
L ++Y VS G TL IK A D G + + G + + LT+ +
Sbjct: 33077 LTNSEEYRYGVS--GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAP 33134
Query: 420 KFVSNLKNVRVKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIE 478
F+S ++ + E CE++ + + W K+ + + S++ L I
Sbjct: 33135 AFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIR 33194
Query: 479 DAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLN 538
+A +SD G+YT+ A ++ +V L V+ +V T L +
Sbjct: 33195 NASVSDSGKYTIKAKNFRGQCSATASLMV-----LPLVEEPSREVVLRTSGDTSLQGSFS 33249
Query: 539 DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFI 598
+ V+ + K+ ++ ++ F SM + S + + I
Sbjct: 33250 SQSVQ---MSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 33306
Query: 599 ADPPTIDPSVLEALAAHA-------------ITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
++ ++ S + L A I++ G + F G+P P+VTW G
Sbjct: 33307 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 33366
Query: 646 MEVTEEE--RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
++ +E R +E +D L I + ++D GL L L N+ GS +AT+++ +
Sbjct: 33367 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 73.9 bits (180), Expect = 9e-13
Identities = 141/679 (20%), Positives = 253/679 (37%), Gaps = 92/679 (13%)
Query: 54 VTRSSNIPAGDSVP----EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIK 109
VT ++ +PA +P V + VT EG+ + G P ++W RE I+
Sbjct: 926 VTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYRED-YQIE 984
Query: 110 ESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKM 169
S + L + ++DS + C A N+ A + T L + E+ +
Sbjct: 985 SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNE-AGTVSTSCYLAVQVSEEFE---- 1039
Query: 170 LKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKV 229
K+ EK E V +D V + T+ ++
Sbjct: 1040 -----------KETTAVTEKFTTEEKRFVESRDV--VMTDTSLTE--------EQAGPGE 1078
Query: 230 EVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQM 289
I KP+ K + +VVF C + +P + W K PL Y KQ
Sbjct: 1079 PAAPYFITKPVVQKLVE-GGSVVFGCQVG-GNPKPHVYWKKSGVPLTTGYRYKVSYNKQT 1136
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKR--MSAELTVLDEP---LKFLGEMKPVKVTERQT 344
G + LVIS +DAG Y++ V +K SA ++L+E L + + + T+
Sbjct: 1137 G-ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTA 1195
Query: 345 AVFEIRLSKKEPNFVWKFNGKELKR---------------------DDKYEITVSEDGLT 383
V E ++ + P FV+ KE ++ D ++ I+ E+ L
Sbjct: 1196 FVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLI 1255
Query: 384 HTLKIKDARLSDSGEFSAEAGNLVQKAQLT-IDRIPIKFVSNLKNVRVKERSRACLECEL 442
++ + + + E E G ++ + + F S +KN R+ E C++
Sbjct: 1256 KEIEYRIIKTTLE-ELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKM 1314
Query: 443 TSKDVT-LRWKKDGQLLMHGTKYSMNH-EGKRAELIIEDAQLSDGGEYTVVAMQDGDPTE 500
+ + + W KDG+ + HG +Y M+ + RA L I D G YT A +
Sbjct: 1315 SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA------SN 1368
Query: 501 YYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQ 560
AI + + + + + T P L+ V I P
Sbjct: 1369 IKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSV------SRSPIRMSPARM 1422
Query: 561 IVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVK 620
+ + ++ M P + T ++ VF+ P + LE
Sbjct: 1423 SPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKP--VSFKCLE---------- 1470
Query: 621 VGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVREDSGLI 678
G TA + G+P+P+ W+ DG ++ + +V ++ Q+L+ + DSG
Sbjct: 1471 -GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVP-ATPSDSGEW 1528
Query: 679 LLKLKNDHGSATATLHLSV 697
+ +N G ++ ++ L+V
Sbjct: 1529 TVVAQNRAGRSSISVILTV 1547
Score = 68.2 bits (165), Expect = 5e-11
Identities = 46/164 (28%), Positives = 76/164 (46%), Gaps = 7/164 (4%)
Query: 546 WLKDGKEITD--LPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA---KGTESEASVFIAD 600
W +DG+ I+ LPG+QI KL P++ + G+Y+ +A G + + +
Sbjct: 39 WFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
T P+ ++ L ++TV+ G ++V G P P V +Y+DG E+ + +
Sbjct: 99 AETAPPNFVQRL--QSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEG 156
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
D L I+ EDSG + N G AT+T L V + P
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Score = 67.4 bits (163), Expect = 9e-11
Identities = 105/466 (22%), Positives = 185/466 (39%), Gaps = 44/466 (9%)
Query: 867 LEDTEYEFRVIAVN---KAGPGQPSVPSSSV-----------VAKDPVKPPGLVQDLHVS 912
+E+TE+ ++ N K G+ V S+V + P KP G + +
Sbjct: 30677 IENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV---IE 30733
Query: 913 DSSNSSISLAWREPAE--GDPPSGYILEM-RAEDTKEWSKCTKIPISGTCYTVGGLIERQ 969
+S ++W+ PA+ G + Y++E A++ EW + TC V L E
Sbjct: 30734 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENA 30792
Query: 970 KYFFRIRAVNEAGVGEPVELDKGVRAMPP---PAAP-KFDLSARLKSHMVVRAGTALCIH 1025
Y+FR+ A N G+ +P+E+ V P P AP K ++A K VV A
Sbjct: 30793 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVV----AWKPP 30848
Query: 1026 AAFSGSPPPDVIWQK-DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEA 1084
A+ G+ + +K + K T+ + F + + +R+ +N GE+
Sbjct: 30849 ASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGES 30908
Query: 1085 RYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
+ +++ P +++ + + P+ N + Q + + WY
Sbjct: 30909 EWS---EISEPITPKSDVPI--QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR 30963
Query: 1145 AAERVFSN--KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLK 1202
+ + ++ KY + G Y+ ++A D+ R T N+ +A L+
Sbjct: 30964 QGKEIIADGLKYRIQEFKGG--YHQLIIASVTDDDATVYQVRAT---NQGGSVSGTASLE 31018
Query: 1203 PYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
E H P+ + + LRG+ ++ F G P P +T KG I N +
Sbjct: 31019 -VEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI 31077
Query: 1263 STSGVCTLVIPT-CTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
T +LV P KD+G Y V +N G D+ + L V D D
Sbjct: 31078 VTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPD 31123
Score = 62.8 bits (151), Expect = 2e-09
Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 1/115 (0%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P V+ LK TV+ G+ T+ C G P PTVT Y+ D I ++ F SG+ L+I
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD-KSVVASITESLQKKSKHLM 1326
+DSG ++ NE G +SC L V ++ + ++TE + K +
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFV 1057
Score = 62.8 bits (151), Expect = 2e-09
Identities = 127/605 (20%), Positives = 241/605 (39%), Gaps = 84/605 (13%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P ++ + VT G+ A ++ G P I W R G + +S K S + H L
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR-FGKELIQSRKYKMSSDGRTHTLT 30591
Query: 127 LEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
+ +D Y CIA+N+ + + T S L+ + + LK++ A +
Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGE-VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLR--- 30647
Query: 187 NEKEMLEILSKVPK----------KDFEKVCME----YGFTDFRGLLRKLKEMKKKVE-- 230
++ I VP ++ E + +E Y + + RK K KV+
Sbjct: 30648 --LHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLS 30705
Query: 231 -----VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTE---PLRIQYSLG 282
V+AI ++ ++DK K +V + +++ + + W + Y +
Sbjct: 30706 NVFGTVDAILDVE-IQDKPDKPTGPIVIEALLK---NSAVISWKPPADDGGSWITNYVVE 30761
Query: 283 KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDK---RMSAELTV-LDEPLKFLGEMKPVK 338
K + K+ G ++ LV S +++ I +L+ R+SA+ T + +PL+ +
Sbjct: 30762 KCEAKE-GAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKS 30820
Query: 339 VTERQTAVFE---IRLSKKEPNFVWK--------------FNGKELKRDDKYEITVSE-- 379
E+ A + ++K WK +E K++ +T E
Sbjct: 30821 PFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIR 30880
Query: 380 ----------DGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVR 429
+GL + ++K L E+S + + K+ + I F L+N+
Sbjct: 30881 ETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQ--APHFKEELRNLN 30938
Query: 430 VKERSRACLECELTSKDVTL-RWKKDG-QLLMHGTKYSMNH-EGKRAELIIEDAQLSDGG 486
V+ +S A L C++T + +W + G +++ G KY + +G +LII D
Sbjct: 30939 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDAT 30998
Query: 487 EYTVVAMQDGDPTEYYSTAIVTVEERLATVKS--GMSDVHAATGSPAELCVVLNDEKVEG 544
Y V A G ++ V V ++ K+ GM VHA G + + + +
Sbjct: 30999 VYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPV 31058
Query: 545 VWLKDGKEITDLPG-MQIVKQGAVHKLIFPSMGPEHE--GKYTFRAKG----TESEASVF 597
+ + G+++ D G Q++ + L+FP+ G E + G Y AK + +
Sbjct: 31059 ITWQKGQDLIDNNGHYQVIVTRSFTSLVFPN-GVERKDAGFYVVCAKNRFGIDQKTVELD 31117
Query: 598 IADPP 602
+AD P
Sbjct: 31118 VADVP 31122
Score = 59.7 bits (143), Expect = 2e-08
Identities = 70/309 (22%), Positives = 126/309 (40%), Gaps = 28/309 (9%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTK--GRETITKSKNHS 1058
AP F R ++ + G + SG P P++ W K+ +P +I++S+N
Sbjct: 33133 APAFISQPRSQN---INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVY 33189
Query: 1059 QFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNH 1118
I + SDSG Y I +N G+ + V L L EE V L +
Sbjct: 33190 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV---------LPLVEEPSREVVLRTSG 33240
Query: 1119 SPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+Q + + M A++ + FS+ + + + + + + + +S
Sbjct: 33241 DTSLQGSFSSQSVQMSASKQEASFSS-----FSSS-SASSMTEMKFASMSAQSMSSMQES 33294
Query: 1179 --EPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPH-TVLRGQDCTMTCA 1235
E S + N Q++ ++K+ K R P + L ++ G+ T+ CA
Sbjct: 33295 FVEMSSSSFMGISNMTQLESSTSKML---KAGIRGIPPKIEALPSDISIDEGKVLTVACA 33351
Query: 1236 FLGNPRPTVTLYKGDVNITANS--KFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGK 1293
F G P P VT G I + +F +T + TL+I +D G Y++ + NE G
Sbjct: 33352 FTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGS 33411
Query: 1294 DRSSCTLTV 1302
D ++ + +
Sbjct: 33412 DSATVNIHI 33420
Score = 57.4 bits (137), Expect = 9e-08
Identities = 77/307 (25%), Positives = 121/307 (39%), Gaps = 34/307 (11%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI--TKSKNHS 1058
AP+ L R++SH V G P +V W +GV + I T +
Sbjct: 32373 APRITL--RMRSHRVP-CGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVL 32429
Query: 1059 QFLINSTKRSDSGVYRILLQNEFGEAR--YDIHVRVADFPRPPTNLRLFEEVPNTVTLTW 1116
I DSG YR + N GEA + V D+ + R EEVP +V
Sbjct: 32430 TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRR-DEEVPRSVF--- 32485
Query: 1117 NHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIG 1176
P++ EA+ + + S ++ V S L ++ ++
Sbjct: 32486 ---PELTRT-EAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 32541
Query: 1177 DSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAF 1236
+ + L+ + T + K+K A R +T + TV G+ +C
Sbjct: 32542 EEKSLEEKST-----------TRKIKT------TLAARILTKPRSMTVYEGESARFSCDT 32584
Query: 1237 LGNPRPTVT-LYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDR 1295
G P PTVT L KG V ++ +++ +T T I + D G+YSV+VEN GK
Sbjct: 32585 DGEPVPTVTWLRKGQV-LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQE 32643
Query: 1296 SSCTLTV 1302
+ TLT+
Sbjct: 32644 AEFTLTI 32650
Score = 55.8 bits (133), Expect = 3e-07
Identities = 99/494 (20%), Positives = 176/494 (35%), Gaps = 85/494 (17%)
Query: 316 RMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYE 374
R+ A + + P + +K V V E ++ E +S P W +++ ++
Sbjct: 931 RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQ 990
Query: 375 ITVSEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTID----------RIPIK 420
IT + G+ L I++A DSG F+ EAG + L + + K
Sbjct: 991 ITF-QSGIAR-LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1048
Query: 421 FVSNLKNVRVKERSRACLECELTSKDVT-------------------------------- 448
F + K V+ R + LT +
Sbjct: 1049 FTTEEKRF-VESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1107
Query: 449 -----LRWKKDGQLLMHGTKYSMNHEGKRAE--LIIEDAQLSDGGEYTVVAMQDGDPTEY 501
+ WKK G L G +Y +++ + E L+I D GEYT+V T
Sbjct: 1108 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS- 1166
Query: 502 YSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQI 561
++A + E + ++ T A + E G + ++ + I
Sbjct: 1167 -ASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALI 1225
Query: 562 VKQGAVHKLIFPSMGPEHE-----------GKYTFRAKGT----------ESEASVFIAD 600
K+ A ++ + + E + +R T E + +V I++
Sbjct: 1226 RKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISE 1285
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
++ + + I +G T H K+ G PLPK+ WYKDG + ER M+ +
Sbjct: 1286 SEAVESGFDSRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQ 1343
Query: 661 D-QALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
D +A L I + ED G+ N G+A + L V P P G ++
Sbjct: 1344 DGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV--EPAAPLGAPTYIPTLEPVSR 1401
Query: 720 MKWKAPKDNGGRPV 733
++ +P+ P+
Sbjct: 1402 IRSLSPRSVSRSPI 1415
Score = 54.3 bits (129), Expect = 8e-07
Identities = 33/96 (34%), Positives = 41/96 (42%)
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
HAPR ++ H V GQ+ P V Y V + +SK Y +TSGV TL
Sbjct: 32372 HAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTL 32431
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKD 1306
I C DSG Y + N G+ TL V D
Sbjct: 32432 EILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGD 32467
Score = 52.8 bits (125), Expect = 2e-06
Identities = 66/296 (22%), Positives = 108/296 (36%), Gaps = 50/296 (16%)
Query: 251 VVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL 310
V + C +E D + ++ W G L + KY++ +L + ++ D G Y
Sbjct: 31585 VKYVCKIENYDQSTQVTWYFGVRQLE---NSEKYEITYEDGVAILYVKDITKLDDGTYRC 31641
Query: 311 SVGD-------------------------------KRMSAELTVLDEPLKFLGEMKPVKV 339
V + KR + + +L+ P +F +
Sbjct: 31642 KVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTA 31701
Query: 340 TERQTAVFEIRLS-KKEPNFVWKFNGKELKR-DDKYEITVSEDGLTHTLKIKDARLSDSG 397
+ F + ++ EP+ W +G+++K D+ + T D + L I D
Sbjct: 31702 YVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDA 31761
Query: 398 EFSAEAGNLVQ----KAQLTIDRIPIKFVSNLK--------NVRVKERSRACLECELTS- 444
E++ A N KA+LT+ P S L+ N +E C E ++
Sbjct: 31762 EYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGI 31821
Query: 445 KDVTLRWKKDGQLLMHGTKYSMNHEG-KRAELIIEDAQLSDGGEYTVVAMQDGDPT 499
TL+W+KDGQ L G + HEG L I D D G Y V A T
Sbjct: 31822 PPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGST 31877
Score = 52.4 bits (124), Expect = 3e-06
Identities = 70/313 (22%), Positives = 120/313 (38%), Gaps = 39/313 (12%)
Query: 999 PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-TKG---RETITKS 1054
PAAP F ++ + +V G ++ G+P P V W+K GVP T G + + K
Sbjct: 1079 PAAPYF-ITKPVVQKLV--EGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQ 1135
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+ +I+ T D+G Y I+++N+ GE + L EE + +
Sbjct: 1136 TGECKLVISMTFADDAGEYTIVVRNKHGET--------------SASASLLEEADYELLM 1181
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKY-YFRVVARN 1173
Q A ++ + TA + +E + +Y L +K VV R
Sbjct: 1182 KSQQEMLYQTQVTA-FVQEPKVGETAPGFVYSE--YEKEYEKEQALIRKKMAKDTVVVRT 1238
Query: 1174 EIGDSE-PLDSRDTWLINKDQIQDLSAKLKPYEKKDWRH------------APRFVTPLK 1220
+ D E + S + LI + + + + L+ ++D F + +K
Sbjct: 1239 YVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIK 1298
Query: 1221 PHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN-STSGVCTLVIPTCTLKD 1279
+ +L G T C G P P + YK I ++ + G +L IP +D
Sbjct: 1299 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358
Query: 1280 SGDYSVLVENELG 1292
G Y+ N G
Sbjct: 1359 EGIYTAFASNIKG 1371
Score = 52.4 bits (124), Expect = 3e-06
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFW--YNSTSGVCT 1269
AP F+T ++ G C GNP+P V K V +T ++ YN +G C
Sbjct: 1081 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1140
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
LVI D+G+Y+++V N+ G+ +S +L
Sbjct: 1141 LVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 51.2 bits (121), Expect = 6e-06
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 13/109 (11%)
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG----VP 1044
L G+R +PP L S + + G L + AF+G P P+V W G
Sbjct: 33320 LKAGIRGIPPKIEA-------LPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQ 33372
Query: 1045 TKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG--EARYDIHVR 1091
+GR I + + + +I ++ D G+Y + L NEFG A +IH+R
Sbjct: 33373 EQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 33421
Score = 50.8 bits (120), Expect = 8e-06
Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 8/197 (4%)
Query: 330 FLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKI 388
F ++ V V E TA FE +S P W +G+ + + +S L I
Sbjct: 8 FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTI 67
Query: 389 KDARLSDSGEFSAEA----GNLVQKAQLTI--DRIPIKFVSNLKNVRVKERSRACLECEL 442
++SG +S +A G A+L + + P FV L+++ V++ S+ L+ +
Sbjct: 68 PAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRV 127
Query: 443 TSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEY 501
T +++ +DG + + ++ EG L+I +A D G Y+V A
Sbjct: 128 TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATS 187
Query: 502 YSTAIVTVEERLATVKS 518
+ +V EE + K+
Sbjct: 188 TAELLVQGEEEVPAKKT 204
Score = 50.4 bits (119), Expect = 1e-05
Identities = 25/96 (26%), Positives = 49/96 (51%)
Query: 1207 KDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG 1266
K+ AP F++ + + GQ+ TC G P P + +K ++ I+ +S + +
Sbjct: 33128 KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN 33187
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
V +L I ++ DSG Y++ +N G+ ++ +L V
Sbjct: 33188 VYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223
Score = 50.1 bits (118), Expect = 1e-05
Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVRE 673
++ V G TA + G P+P+V+W++DG ++ V + + +A LTI +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 674 DSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
+SG LK N G AT+T L V PP
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 50.1 bits (118), Expect = 1e-05
Identities = 84/364 (23%), Positives = 140/364 (38%), Gaps = 55/364 (15%)
Query: 384 HTLKIKD-------ARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSN-LKNVRVKERSR 435
HTL KD AR+S G ++ G V A++ + I I VS + + +E
Sbjct: 31527 HTLIKKDLNMVVSAARISCGGAIRSQKG--VSVAKVKVASIEIGPVSGQIMHAVGEEGGH 31584
Query: 436 ACLECELTSKDVTLR--WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAM 493
C++ + D + + W + L + KY + +E A L ++D D G Y +
Sbjct: 31585 VKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 31644
Query: 494 QD-GDPTEYYSTAIVTVEE-------RLATVKSGMSDVHAATGSPAELCVVLNDEKV--- 542
D G+ + Y + V E R +D P E + L ++
Sbjct: 31645 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 31704
Query: 543 EGV---------------WLKDGKEITDLPGMQIVK-----QGAVHKLIFPSMGPEHEGK 582
E V W K G++I PG K +++L S+ + + +
Sbjct: 31705 ENVRFGVTITVHPEPHVTWYKSGQKIK--PGDNDKKYTFESDKGLYQLTINSVTTDDDAE 31762
Query: 583 YTFRAKGTESEAS------VFIADPPTIDP--SVLEALAAHAITVKVGHTAHIKVPFRGK 634
YT A+ E S V + PPT + + L A+A + G + ++ G
Sbjct: 31763 YTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANA-ECQEGQSVCFEIRVSGI 31821
Query: 635 PLPKVTWYKDGMEVTEEERVSM-ERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
P P + W KDG ++ + + G D L I + + ED+G + N GS +
Sbjct: 31822 PPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQA 31881
Query: 694 HLSV 697
HL V
Sbjct: 31882 HLQV 31885
Score = 48.9 bits (115), Expect = 3e-05
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P FV L+ TV +G + G P P V Y+ I ++ F + + +L+I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD------KSVV--ASITESLQKK 1321
+DSG YSV N +G+ S+ L V +++ K++V A I+ES Q +
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 48.9 bits (115), Expect = 3e-05
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 3/99 (3%)
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTK---GRETITK 1053
PP + + RL ++ + G ++C SG PPP + W+KDG P E I +
Sbjct: 31787 PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHE 31846
Query: 1054 SKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV 1092
++ I T D+G YR+ N G H++V
Sbjct: 31847 GLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 31885
Score = 47.8 bits (112), Expect = 7e-05
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA---NSKFWYNSTSGVCT 1269
P F PL T G++ +P P VT YK I + K+ + S G+
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 31749
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L I + T D +Y+V+ N+ G+D LTV
Sbjct: 31750 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 47.4 bits (111), Expect = 9e-05
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSK-FWYNSTSGVCTL 1270
AP+ ++ TV +G D +G P P YK V I + + +WY VC L
Sbjct: 2077 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCEL 2136
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQ 1319
VI T +DS V N G+ S L V K + + T+ LQ
Sbjct: 2137 VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ----LITFTQELQ 2181
Score = 47.4 bits (111), Expect = 9e-05
Identities = 62/288 (21%), Positives = 102/288 (35%), Gaps = 37/288 (12%)
Query: 1029 SGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
+G+ P V W KD + + G+ I+ +N + + + DSG Y NE G+
Sbjct: 8177 TGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSC 8236
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWY--- 1143
+ + + PP+ + E TV T +S ++ + T WY
Sbjct: 8237 TAQLNIKERLIPPSFTKRLSE---TVEETEGNSFKLEGR------VAGSQPITVAWYKNN 8287
Query: 1144 ------TAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDL 1197
+ E F N V + R N+ G T ++ D L
Sbjct: 8288 IEIQPTSNCEITFKNNTLVLQV--------RKAGMNDAG-------LYTCKVSNDAGSAL 8332
Query: 1198 SAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS 1257
K+ + P F L P TV G+ ++C G+ + K I +
Sbjct: 8333 CTS--SIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSD 8390
Query: 1258 KFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+ ++ SG L + DSGDY N G D + +T+ DK
Sbjct: 8391 RCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDK 8438
Score = 47.4 bits (111), Expect = 9e-05
Identities = 55/226 (24%), Positives = 100/226 (44%), Gaps = 30/226 (13%)
Query: 220 RKLKEMKKKVEVEAIRILK-------PLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGT 272
R +K++K++ + +R+L+ PL +K V V F + + P + W K
Sbjct: 31671 RTMKKIKRRTDT--MRLLERPPEFTLPLYNKTAYVGENVRFGVTITVH-PEPHVTWYKSG 31727
Query: 273 EPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPL 328
+ ++ + KY + Y L I++V +D Y++ G+ A+LTV P
Sbjct: 31728 QKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPP 31787
Query: 329 KFLGEMKPV--------KVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSE 379
++P+ + E Q+ FEIR+S P W+ +G+ L EI
Sbjct: 31788 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII--H 31845
Query: 380 DGLT-HTLKIKDARLSDSGEF----SAEAGNLVQKAQLTIDRIPIK 420
+GL + L I+D D+G + + AG+ +A L ++R+ K
Sbjct: 31846 EGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYK 31891
Score = 45.4 bits (106), Expect = 4e-04
Identities = 69/296 (23%), Positives = 111/296 (37%), Gaps = 39/296 (13%)
Query: 1032 PPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P +VIW K + + GR I +I + D+G Y L + + + +H
Sbjct: 12489 PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVH 12548
Query: 1090 VRVADFPRPPTNLRLFE-EVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAER 1148
A+F P NL + E E V S VQ KRD T
Sbjct: 12549 ELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQ---------WKRDDKTLE------- 12592
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKD 1208
+KY V + G+K R + L T+++ + +A L EK
Sbjct: 12593 -SGDKYDV--IADGKK-------RVLVVKDATLQDMGTYVVMVGAAR-AAAHLTVIEKL- 12640
Query: 1209 WRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVC 1268
R V PLK V Q+ C + ++ + I +SK+ V
Sbjct: 12641 -----RIVVPLKDTRVKEQQEVVFNCE-VNTEGAKAKWFRNEEAIFDSSKYIILQKDLVY 12694
Query: 1269 TLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASI--TESLQKKS 1322
TL I L D +Y+V + N G++ S + +++D +V + E+++KKS
Sbjct: 12695 TLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKS 12750
Score = 45.4 bits (106), Expect = 4e-04
Identities = 74/329 (22%), Positives = 131/329 (39%), Gaps = 40/329 (12%)
Query: 369 RDDKYEITVSEDGLTHTLKIKDARLSDSG--EFSAEAGNLVQKAQLTIDRIPIKFVSNLK 426
R+ K ++T + + L+ A + + E S E + +K + T+ + ++ +
Sbjct: 32512 REVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTL---AARILTKPR 32568
Query: 427 NVRVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDG 485
++ V E A C+ + V T+ W + GQ+L ++ + ++ I Q SD
Sbjct: 32569 SMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDE 32628
Query: 486 GEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGV 545
G Y+VV E T +T+++ T K+ S + P V + E V
Sbjct: 32629 GNYSVVVENSEGKQEAEFT--LTIQKARVTEKAVTSPPRVKSPEPR----VKSPEAV--- 32679
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
K K + + + K + P+ E K T TE + ++ PP I
Sbjct: 32680 --KSPKRVKS-------PEPSHPKAVSPT-----ETKPT----PTEKVQHLPVSAPPKI- 32720
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL- 664
L+A A+ I K+ V R K +VTWYKDG ++ E D
Sbjct: 32721 TQFLKAEASKEI-AKLTCVVESSV-LRAK---EVTWYKDGKKLKENGHFQFHYSADGTYE 32775
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATL 693
L I+N D G + ++ + G++ L
Sbjct: 32776 LKINNLTESDQGEYVCEISGEGGTSKTNL 32804
Score = 45.1 bits (105), Expect = 5e-04
Identities = 32/106 (30%), Positives = 42/106 (39%)
Query: 1197 LSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITAN 1256
++ K +P + P VT L+ TV G PRPT K IT
Sbjct: 32836 VTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG 32895
Query: 1257 SKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
K+ + G L I DSG Y+ V+N G SSC LT+
Sbjct: 32896 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 32941
Score = 43.1 bits (100), Expect = 0.002
Identities = 46/213 (21%), Positives = 81/213 (38%), Gaps = 6/213 (2%)
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMS---DVHAATGSPAELCVVLNDEKVEGV 545
+V + G +AI T+++ L+ S V A T P+E V +
Sbjct: 822 SVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQF 881
Query: 546 WLKDGKEI-TDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
D + G+++ K+ V E + AK TE+ + P
Sbjct: 882 PFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVT 941
Query: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL 664
P+++ L +TV G + ++ G P P VTWY++ ++ + A
Sbjct: 942 PPTLVSGLKN--VTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIAR 999
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
L I EDSG N+ G+ + + +L+V
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 43.1 bits (100), Expect = 0.002
Identities = 73/336 (21%), Positives = 119/336 (35%), Gaps = 70/336 (20%)
Query: 1030 GSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
G P P+ W DG V + + K +I SDSG + ++ QN G +
Sbjct: 1482 GRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSI 1541
Query: 1087 DI--HVRVADFPRPP--------TNLRLFEEVPNTVTLTWNHSPDVQ------------- 1123
+ V + P N++ + V T N +PD+
Sbjct: 1542 SVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKY 1601
Query: 1124 -------EDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTG-----------------L 1159
GEA I + + WYTA + + T +
Sbjct: 1602 PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLI 1661
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSR---DTWLINKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
+P Y + +A E+ EPL R + W + + D + KP+ KK +
Sbjct: 1662 IPRGTYRAKEIAAPEL---EPLHLRYGQEQW--EEGDLYDKEKQQKPFFKKK-------L 1709
Query: 1217 TPLKPHTVLRGQ-DCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
T L+ +C +T +G+P V + A ++ + G C+L
Sbjct: 1710 TSLRLKRFGPAHFECRLTP--IGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVA 1767
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVV 1311
+DSG + N+ G D +S TL V KD+KS+V
Sbjct: 1768 YSRDSGIITCRATNKYGTDHTSATLIV--KDEKSLV 1801
Score = 43.1 bits (100), Expect = 0.002
Identities = 62/334 (18%), Positives = 120/334 (35%), Gaps = 32/334 (9%)
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSG 1071
+ V++G A SG P P + W K+ + T + L+ D+
Sbjct: 3248 VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAA 3307
Query: 1072 VYRILLQNEFGEARYD--IHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH 1129
VY +N++G A + V V + P + ++ P +T + +
Sbjct: 3308 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP--PAIITPLQDTVTSEGQPARFQ 3365
Query: 1130 YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLI 1189
+ D + WY+ +++ +++ R F + EI ++ P D +
Sbjct: 3366 CRVSGTDLKVS-WYSKDKKIKPSRFF-------RMTQFEDTYQLEIAEAYPEDEGTYTFV 3417
Query: 1190 NKDQIQDLSA---------------KLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTC 1234
+ + +S+ +++ + + + AP ++P V G TC
Sbjct: 3418 ASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTC 3477
Query: 1235 AFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKD 1294
P +K I + K S+ + +L I + D G+Y+ NE G
Sbjct: 3478 EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 3537
Query: 1295 RSSCTLTV---YDKDDKSVVASITESLQKKSKHL 1325
+ TLTV Y S S+T + K +K +
Sbjct: 3538 SCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFI 3571
Score = 42.0 bits (97), Expect = 0.004
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 588 KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGME 647
K +E + V P T+D + L + V G + + KP +V WY +G+E
Sbjct: 32354 KTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVE 32413
Query: 648 VTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSAT--ATLHLS 696
+ E ++ L I +C +DSG N G A+ ATL ++
Sbjct: 32414 LQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVT 32464
Score = 40.0 bits (92), Expect = 0.015
Identities = 33/111 (29%), Positives = 45/111 (40%), Gaps = 15/111 (13%)
Query: 1002 PKFDLSARLKSHMV---VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE-----TITK 1053
P+F L K+ V VR G + +H P P V W K G K + T
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVH------PEPHVTWYKSGQKIKPGDNDKKYTFES 31743
Query: 1054 SKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRL 1104
K Q INS D Y ++ +N++GE + V P PPT+ L
Sbjct: 31744 DKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP-PPTDSTL 31793
Score = 39.7 bits (91), Expect = 0.019
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS--KFWYNSTSGVCT 1269
AP F PL+ VL G T G P P V+ ++ I+ ++ + + G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L IP T +SG YS+ N G+ S+ L V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 39.7 bits (91), Expect = 0.019
Identities = 62/301 (20%), Positives = 101/301 (33%), Gaps = 54/301 (17%)
Query: 1008 ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKS---KNHSQFLINS 1064
+R+K++ ++ G + H SG P P + W KDG K E + I
Sbjct: 1295 SRIKNYRILE-GMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPV 1353
Query: 1065 TKRSDSGVYRILLQNEFGEARYD--IHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDV 1122
D G+Y N G A ++V A PT + E V +L+
Sbjct: 1354 VLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLS------- 1406
Query: 1123 QEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
R S + + R+ + + + P R + L+
Sbjct: 1407 -----------PRSVSRSPIRMSPARMSPARMSPARMSPAR-----------MSPGRRLE 1444
Query: 1183 SRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP 1242
D + Q++ L + P FV L GQ +G P P
Sbjct: 1445 ETD-----ESQLERL-------------YKPVFVLKPVSFKCLEGQTARFDLKVVGRPMP 1486
Query: 1243 -TVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLT 1301
T + G + + G +L+I T DSG+++V+ +N G+ S LT
Sbjct: 1487 ETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILT 1546
Query: 1302 V 1302
V
Sbjct: 1547 V 1547
Score = 39.7 bits (91), Expect = 0.019
Identities = 49/220 (22%), Positives = 90/220 (40%), Gaps = 24/220 (10%)
Query: 80 EGDKAVFRARVQGNAKPHISWKRE-SGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNY 138
EG F RV G P + W+++ + + + +I ++ ++ + L + +D+ Y
Sbjct: 31808 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD-YYALHIRDTLPEDTGYY 31866
Query: 139 KCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANEKEMLEILS-- 196
+ A+N L V E++ +KK K + QK++ M EILS
Sbjct: 31867 RVTATNTAGSTSCQAHLQV----ERLRYKKQEFKSKEEHERHVQKQIDKTLRMAEILSGT 31922
Query: 197 ------KVPKKDFEKVCMEY----GFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETK 246
+V K+ + + Y +G R E+++K E +R+ + +
Sbjct: 31923 ESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFR--LEIEEKKEERKLRMPYDVPEPRKY 31980
Query: 247 VDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSL-GKYD 285
TT+ D ++ P M W K +R QY + GK D
Sbjct: 31981 KQTTIEEDQRIKQFVPMSDMKWYK---KIRDQYEMPGKLD 32017
Score = 39.3 bits (90), Expect = 0.025
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 3/89 (3%)
Query: 618 TVKVGHTAHIKVPFRGKPLPKVTWYKDGMEV---TEEERVSMERGEDQALLTISNCVRED 674
T VG V P P VTWYK G ++ +++ + E + LTI++ +D
Sbjct: 31700 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 31759
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKP 703
+ +N +G + L+V P P
Sbjct: 31760 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 31788
Score = 38.5 bits (88), Expect = 0.043
Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 1/106 (0%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV-L 125
P F + Q V EG A F A + G P +SW R+ + + S + L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171
+ +T +S Y A+N A T LLV +F + L+
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ 111
Score = 38.5 bits (88), Expect = 0.043
Identities = 32/145 (22%), Positives = 60/145 (41%), Gaps = 10/145 (6%)
Query: 17 EFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGDSVPEFVEKPQPV 76
++ +++ + F + + V + RR I R+ + + PEF
Sbjct: 31646 DYGEDSSYAELFVKGVREVYDYYCRRTMKKIKR------RTDTMRLLERPPEFTLPLYNK 31699
Query: 77 TAPEGDKAVFRARVQGNAKPHISWKRESGIPIK---ESAKIFYDSINKEHVLKLEPLTSD 133
TA G+ F + + +PH++W + SG IK K ++S + L + +T+D
Sbjct: 31700 TAYVGENVRFGVTITVHPEPHVTWYK-SGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 31758
Query: 134 DSDNYKCIASNDHADAIYTVSLLVT 158
D Y +A N + + L VT
Sbjct: 31759 DDAEYTVVARNKYGEDSCKAKLTVT 31783
Score = 37.7 bits (86), Expect = 0.074
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 81 GDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKC 140
G+ V G +P+ISW ++ G P+K++ ++ + VL ++ DD Y
Sbjct: 24326 GEDLKIEIPVIGRPRPNISWVKD-GEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 24384
Query: 141 IASNDHADAIYTVSLLVTE 159
A+N A +S++V E
Sbjct: 24385 TATNSAGTATENLSVIVLE 24403
Score = 37.4 bits (85), Expect = 0.096
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 1/98 (1%)
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
+ P V +P VL G+ C G P+P V Y I + +F G+
Sbjct: 1838 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHY 1896
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
L I C D+G+ V EN G L + ++D
Sbjct: 1897 LDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1934
Score = 37.0 bits (84), Expect = 0.13
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 1029 SGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG 1082
+G P P IW KDG + G+ +++ K I+ T SDSG+Y ++N G
Sbjct: 32876 TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAG 32931
Score = 35.4 bits (80), Expect = 0.37
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDG----VPTKGRETITKSKNHSQFLINSTKRSD 1069
+VV G+ A SG P P+V W +DG T I+ S ++ I + +++
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKAN 74
Query: 1070 SGVYRILLQNEFGEARYDIHVRVADFPRPP 1099
SG Y + N G+A + V PP
Sbjct: 75 SGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 35.4 bits (80), Expect = 0.37
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 4/119 (3%)
Query: 54 VTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAK 113
+T S++P P F E+ + + A +V G+ KP + W R+ I + K
Sbjct: 30917 ITPKSDVPI--QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 30974
Query: 114 I-FYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171
+ H L + +T DD+ Y+ A+N T SL V E K+ K L+
Sbjct: 30975 YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV-EVPAKIHLPKTLE 31032
Score = 34.3 bits (77), Expect = 0.82
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDG---VPTK-GRETITKSKNHSQFLINSTKRSDSG 1071
++ G+ L + +G+P PD++W K+ VP K + I +K + I+ST DS
Sbjct: 1567 IKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSA 1626
Query: 1072 VYRILLQNEFGE--ARYDIHVRVADFPRPPTNLRL 1104
Y N+ G R ++V V +F P +L
Sbjct: 1627 WYTATAINKAGRDTTRCKVNVEV-EFAEPEPERKL 1660
Score = 34.3 bits (77), Expect = 0.82
Identities = 25/115 (21%), Positives = 40/115 (34%)
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
+ P F++ K T G+ C G P K ++ + + + L
Sbjct: 3549 YPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHIL 3608
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQKKSKHL 1325
+ T++D G YS N+ G D L + DK +S K HL
Sbjct: 3609 ELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHL 3663
Score = 33.9 bits (76), Expect = 1.1
Identities = 30/134 (22%), Positives = 62/134 (46%), Gaps = 12/134 (8%)
Query: 296 VISNVNMNDAGIYSLSVGDKR-----MSAELTVLDEPLKFLGEMKPV----KVTERQTAV 346
VI+N+ + ++ + +++ S + ++ + L ++KP V Q
Sbjct: 23189 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 23248
Query: 347 FEIRLS-KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
E+ +S + +P W +G LK+ + +T S D LT TL IK+ D G++ N
Sbjct: 23249 IEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD-LT-TLSIKETHKDDGGQYGITVAN 23306
Query: 406 LVQKAQLTIDRIPI 419
+V + +I+ + +
Sbjct: 23307 VVGQKTASIEIVTL 23320
Score = 33.5 bits (75), Expect = 1.4
Identities = 36/161 (22%), Positives = 65/161 (40%), Gaps = 12/161 (7%)
Query: 973 FRIRAVNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGS 1031
+ ++A N +G EL PP + RL+S M VR G+ + + +G
Sbjct: 78 YSLKATNGSGQATSTAELLVKAETAPP------NFVQRLQS-MTVRQGSQVRLQVRVTGI 130
Query: 1032 PPPDVIWQKDGVPTKGR--ETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P P V + +DG + I++ + LI DSG Y + N G A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAE 190
Query: 1090 VRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHY 1130
+ V P + + + +T ++ + +++ EAH+
Sbjct: 191 LLVQGEEEVPA--KKTKTIVSTAQISESRQTRIEKKIEAHF 229
Score = 33.1 bits (74), Expect = 1.8
Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 76 VTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDS 135
V A GD V G KP ++WK+ I +K++ ++ +++ +L + DS
Sbjct: 21075 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQI-LKQTQRVNFETTATSTILNINECVRSDS 21133
Query: 136 DNYKCIASN 144
Y A N
Sbjct: 21134 GPYPLTARN 21142
Score = 33.1 bits (74), Expect = 1.8
Identities = 33/135 (24%), Positives = 53/135 (39%), Gaps = 17/135 (12%)
Query: 26 QTFSQT--TKIVGEEVVRRKSSSIVEFFSLVTR----SSNIPAGD-SVPEFVEKPQ---- 74
QT+S +K EV + K S++EF S + G +V E + P+
Sbjct: 27507 QTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLS 27566
Query: 75 -----PVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEP 129
VT G +G KP ISW ++ G+P+KES + + + L ++
Sbjct: 27567 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKD-GLPLKESEFVRFSKTENKITLSIKN 27625
Query: 130 LTSDDSDNYKCIASN 144
+ Y I N
Sbjct: 27626 AKKEHGGKYTVILDN 27640
Score = 33.1 bits (74), Expect = 1.8
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEF 399
P WK LK D+ IT ++D TL +KD+ DSG +
Sbjct: 28677 PKVTWKLEEMRLKETDRVSITTTKD--RTTLTVKDSMRGDSGRY 28718
Score = 32.7 bits (73), Expect = 2.4
Identities = 64/277 (23%), Positives = 104/277 (37%), Gaps = 48/277 (17%)
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEF---GEARYDIHVRV 1092
V W KDG K K K + G RIL+ N+ EA Y VR
Sbjct: 12404 VKWFKDGAEIK------KGKKYDII--------SKGAVRILVINKCLLDDEAEYSCEVRT 12449
Query: 1093 ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYII-MKRDASTATWYTAAERVF- 1150
A T L EE T L + +V E + + + + WY E +
Sbjct: 12450 ARTSGMLTVLE--EEAVFTKNLA---NIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIE 12504
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR--DTWLINKDQIQDLSAKLKPYEKKD 1208
+ +Y + L GRK V+ + D+ + R + K ++ +L+A+
Sbjct: 12505 TGRYEI--LTEGRKRIL-VIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAE-------- 12553
Query: 1209 WRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVC 1268
F++ + +L G+ C+ P V + D + + K+ +
Sbjct: 12554 ------FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKKR 12606
Query: 1269 TLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
LV+ TL+D G Y V+V G R++ LTV +K
Sbjct: 12607 VLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 12639
Score = 32.3 bits (72), Expect = 3.1
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query: 280 SLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMK 335
SL K ++ + +L++ NVN D+G Y L+V G K + VLD P G +
Sbjct: 21901 SLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTP----GPPQ 21956
Query: 336 PVKVTE 341
+KV E
Sbjct: 21957 DLKVKE 21962
Score = 32.0 bits (71), Expect = 4.0
Identities = 15/54 (27%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 1247 YKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
Y DV + +N K+ S G L + T +D G+YS +++ + +++C L
Sbjct: 2300 YHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK----KTTCKL 2349
Score = 32.0 bits (71), Expect = 4.0
Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 1244 VTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENE-LGKDRSSCTLTV 1302
VT YKG +T + K+ + + + I T D G YSV+ E G+ RS+ L +
Sbjct: 8864 VTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYL 8923
Query: 1303 YDKDDK 1308
K+ K
Sbjct: 8924 TTKEIK 8929
Score = 32.0 bits (71), Expect = 4.0
Identities = 57/243 (23%), Positives = 90/243 (37%), Gaps = 27/243 (11%)
Query: 1067 RSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDG 1126
RS+ V+ + L++ E ++ + DF T+ LF + P V T E+G
Sbjct: 12244 RSEGKVHTLTLRDVKLEDAGEVQLTAKDFK---THANLFVKEP-PVEFTKPLEDQTVEEG 12299
Query: 1127 EAHYII--MKRDASTATWY-TAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ + R+ + W+ E + S KY + GR V + I D P D
Sbjct: 12300 ATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVA--DGR------VRKLVIHDCTPEDI 12351
Query: 1184 RDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPT 1243
+ KD + + P + F+ PL V + C L
Sbjct: 12352 KTYTCDAKDFKTSCNLNVVPPHVE-------FLRPLTDLQVREKEMARFECE-LSRENAK 12403
Query: 1244 VTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVY 1303
V +K I K+ S V LVI C L D +YS E+ R+S LTV
Sbjct: 12404 VKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC----EVRTARTSGMLTVL 12459
Query: 1304 DKD 1306
+++
Sbjct: 12460 EEE 12462
Score = 32.0 bits (71), Expect = 4.0
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 11/70 (15%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAEL 321
PNV +W K LR + + D ++ L I N N ND+G Y+L++ + +A L
Sbjct: 26216 PNV--LWSKPDTDLRTRAYVDTTD-----SRTSLTIENANRNDSGKYTLTIQNVLSAASL 26268
Query: 322 T----VLDEP 327
T VLD P
Sbjct: 26269 TLVVKVLDTP 26278
Score = 32.0 bits (71), Expect = 4.0
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 9/70 (12%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P +W K L + + D+ + L + N N NDAG Y+L+V G K +
Sbjct: 28385 PTPTAVWSKPDSNLSL-----RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSI 28439
Query: 318 SAELTVLDEP 327
+ + VLD P
Sbjct: 28440 TFTVKVLDTP 28449
Score = 31.6 bits (70), Expect = 5.3
Identities = 50/244 (20%), Positives = 91/244 (37%), Gaps = 37/244 (15%)
Query: 11 QEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVT--RSSNIPAGDSVPE 68
+E E + T + + + V EE + S + + VT + I +P
Sbjct: 9511 EEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPA 9570
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLE 128
+E+P P PE K + + P +P + + + + + E
Sbjct: 9571 KIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEE 9630
Query: 129 PLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPP---APKKKQKKV 185
PL + ++ + I QE+ + KK APP P++ ++ V
Sbjct: 9631 PLPAKVTERHMQIT------------------QEEKVLVAVTKKEAPPKARVPEEPKRAV 9672
Query: 186 ANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEV-----EAIRILKPL 240
EK +L PK++ E T+FR R +KE K +E + I+ + +
Sbjct: 9673 PEEK----VLKLKPKREEEPPAK---VTEFR--KRVVKEEKVSIEAPKREPQPIKEVTIM 9723
Query: 241 EDKE 244
E+KE
Sbjct: 9724 EEKE 9727
Score = 31.6 bits (70), Expect = 5.3
Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 11/129 (8%)
Query: 224 EMKKKVEVEAIRI-LKPLEDKETKVDTTVVFDCIME-LKDPNVKMIWIKGTEPLRIQYSL 281
E ++K+ ++ + +K +E K TTV F I+ + P K W ++
Sbjct: 17500 ECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTDEH- 17556
Query: 282 GKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMKPV 337
Y V+ +L I N D G Y ++V G K ++ LTVLD P G + +
Sbjct: 17557 --YTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINIL 17614
Query: 338 KVTERQTAV 346
VT +
Sbjct: 17615 DVTPEHMTI 17623
Score = 30.8 bits (68), Expect = 9.0
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
Query: 277 IQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPLKFLG 332
IQ SL + + Q G Y L+I+ D+G YS+ SVG +AEL V E
Sbjct: 144 IQSSLD-FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Query: 333 EMKPVKVTERQTAVFEIRLSKK 354
+ K + T + + + R+ KK
Sbjct: 203 KTKTIVSTAQISESRQTRIEKK 224
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 423 bits (1087), Expect = e-118
Identities = 299/1086 (27%), Positives = 497/1086 (45%), Gaps = 54/1086 (4%)
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTV------------SLLVTEGQEKMDFKK 168
++ +L ++ +D+ NY C + D V +L + EG EK +F
Sbjct: 6210 RKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEG-EKAEFVC 6268
Query: 169 MLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDF---EKVCMEYG-FTDFRGLLRKLKE 224
+ K + P K+ K + ++++ K+ + + G + G R
Sbjct: 6269 SISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAH 6328
Query: 225 MKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKY 284
+ +E +RI+ PL+D K VVF+C E+ K W + E + + KY
Sbjct: 6329 L---TVIEKLRIVVPLKDTRVKEQQEVVFNC--EVNTEGAKAKWFRNEEAI---FDSSKY 6380
Query: 285 DVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR-----MSAELTVLDEPLKFLGEMKPVKV 339
+ Q Y L I + +++D Y++S+ + R +A L V +E L+ + +K ++
Sbjct: 6381 IILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIET 6440
Query: 340 TERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEF 399
E+++ F ++++ W NG+E+ D++ V D H L IKD D GE+
Sbjct: 6441 MEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRV--DKYKHMLTIKDCGFPDEGEY 6498
Query: 400 SAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLM 459
AG A+L I P +FV +L++ V E A C+L+ + ++W ++G+ +
Sbjct: 6499 IVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIK 6558
Query: 460 HGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSG 519
G KY +G LII+D +L D EY ++D S A + VEE +
Sbjct: 6559 EGKKYKFEKDGSIHRLIIKDCRLDDECEYAC-GVEDRK-----SRARLFVEEIPVEIIRP 6612
Query: 520 MSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEH 579
D+ A G+ LN +KVE WL++ + Q++ +G +H+L + P
Sbjct: 6613 PQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRD 6672
Query: 580 EGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKV 639
+G+Y F AK E+ A + +A P I A + V VG + VP+ P +
Sbjct: 6673 QGEYRFIAKDKEARAKLELAAAPKIKT------ADQDLVVDVGKPLTMVVPYDAYPKAEA 6726
Query: 640 TWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLD 699
W+K+ ++ + +++ +Q I + D G + L+N HG A ++L V+D
Sbjct: 6727 EWFKENEPLSTK---TIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVID 6783
Query: 700 RPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVT 759
P P + +E E V + W+ P +GG + ++VERR + +K+W+ +
Sbjct: 6784 VPGPVRN-LEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE 6842
Query: 760 NFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAV 818
T + G Y FR+ A N G +P+ET+ V A + + PG +TDV + V
Sbjct: 6843 FTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGV 6902
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
++TW P DGGA + Y++E R K S W + TV ++E EY FRV A
Sbjct: 6903 SLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRA 6962
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYI 936
N+ G G+PS + V DP++ P +L SD + SS+ L W P + G P GYI
Sbjct: 6963 QNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 7022
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
+E E W +C + Y V GL + KY +R+ A N+AGV +P E+ + A
Sbjct: 7023 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 7082
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIW--QKDGVPTKGRETITKS 1054
P DLSA K + V + I +G P P W + T R +
Sbjct: 7083 DAFVEPTMDLSA-FKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTL 7141
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+++ +I+ ++RSD G+Y + L+N +I V V P P L+ + ++V L
Sbjct: 7142 SAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHL 7201
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNE 1174
TW D Y++ KR+ S TW + V ++TV L+ G++Y F+V ARN+
Sbjct: 7202 TWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNK 7261
Query: 1175 IGDSEP 1180
G EP
Sbjct: 7262 CGPGEP 7267
Score = 380 bits (977), Expect = e-105
Identities = 300/1056 (28%), Positives = 483/1056 (45%), Gaps = 93/1056 (8%)
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+MG KY ++ VN+ YS S+ + + + D L+ ++K VT R A
Sbjct: 23103 KMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD--LELADDLKKT-VTIRAGASL 23159
Query: 348 EIRLS---KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKD-ARLSDSGEFSAEA 403
+ +S + P W G +L + T S ++L I D D+G+++ EA
Sbjct: 23160 RLMVSVSGRPPPVITWSKQGIDLASRAIIDTTES-----YSLLIVDKVNRYDAGKYTIEA 23214
Query: 404 GNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWK---KDGQLLMH 460
N K T+ +V+VKE SR VT+ W+ DG ++
Sbjct: 23215 ENQSGKKSATVLVKVYDTPGPCPSVKVKEVSR---------DSVTITWEIPTIDGGAPVN 23265
Query: 461 GTKYSMNHEGKRA---------ELIIEDAQLSDGGEYTVVAMQD-----GDPTEYYSTAI 506
RA + + + L +G Y + + G+P E S A+
Sbjct: 23266 NYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE-TSDAV 23324
Query: 507 VTVEERLATVKSGMSDVHAATGSPA-ELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQG 565
+ E L K + DV +T + A E + ++ G L+ K T+ + +
Sbjct: 23325 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23384
Query: 566 AVHKLIFPSMGPEHEGKYTFRAKG-------TESEASVFIAD---PPTIDPSVLEALAAH 615
V + S+ + + RA+ E+ +V + D PTID S + H
Sbjct: 23385 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIH 23444
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDS 675
V G + +P G+P P +W+ G ++ E ERV++E A LTI D+
Sbjct: 23445 ---VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 23501
Query: 676 GLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQ 735
G L+LKN G+ + T+ + +LD+P PP G ++ E+ + + + W+ P+ +GG P++
Sbjct: 23502 GEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSG 23561
Query: 736 FIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFA 795
++VE+R + W+ + E + T F ++ EG Y FR+ A N G+ L++E +
Sbjct: 23562 YVVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIEC 23620
Query: 796 GNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP 855
+ I PG Q+ DV+++ +T+TW P DGG+ V GYIVER++ ++ WV VNK P
Sbjct: 23621 RSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVP 23680
Query: 856 IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSS 915
+ T+ GL E EYE RV A+N G G+PS PS +VA DP+ PPG Q+ V+D++
Sbjct: 23681 VTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTT 23740
Query: 916 NSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFF 973
+S+SLAW P + G +GY++EM+ D EW+KC P YT+ L + +Y F
Sbjct: 23741 RTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRF 23800
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
R+ A N G GEP E+ V+ P ++L R + + VR G + + G P
Sbjct: 23801 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPF 23860
Query: 1034 PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVA 1093
P W K+G R I S+ H++ +I R DSG Y ++L+N+ G+ I VRV
Sbjct: 23861 PICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVI 23920
Query: 1094 DFPRPPTNLRLFEEVP-NTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERV 1149
P P ++++ +V ++W D DG A YI+ +R+ A WYT RV
Sbjct: 23921 GSPNSPEGPLEYDDIQVRSVRVSWRPPAD---DGGADILGYILERREVPKAAWYTIDSRV 23977
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
V GL +Y+FRV A N+ G S+PL S + P K
Sbjct: 23978 RGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE-----------------PVTPKTP 24020
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP------TVTLYKGDVNITANSKFWYNS 1263
+ P P P VL D T + L RP VT Y + T+ K+ ++
Sbjct: 24021 LNPPE--PPSNPPEVL---DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHN 24075
Query: 1264 TSGVCTLVIPTCTLKDSGDYS--VLVENELGKDRSS 1297
+ + T + L +Y ++ +N++G +S
Sbjct: 24076 KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETS 24111
Score = 377 bits (967), Expect = e-104
Identities = 245/766 (31%), Positives = 380/766 (49%), Gaps = 52/766 (6%)
Query: 448 TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIV 507
+L W K L+ T+Y + E L+ G + PTEY
Sbjct: 12830 SLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG-----SSPPSKPTEY------ 12878
Query: 508 TVEERLATVKSGMSDVHAATGSPAELCVVL----NDEKVEGVWLKDGKEITDLPGMQIVK 563
V R+ G +V T S L K+ G ++ E LPG + V+
Sbjct: 12879 -VTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFV----EACKLPGDKWVR 12933
Query: 564 -QGAVHKLI---FPSMGPEHEGKYTFRA----------KGTESEASVFIAD--PPTIDPS 607
A H++ + + G E + +Y FRA S+ +A+ PP ID S
Sbjct: 12934 CNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS 12993
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
V +TVK G + GKP+P V+W KDG + E + M + L +
Sbjct: 12994 VA---MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLEL 13050
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKD 727
+ R+DSG + +N GS +AT+ L VLD+P PP V+ ++ + W+ P +
Sbjct: 13051 FSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPAS-VKINKMYSDRAMLSWEPPLE 13109
Query: 728 NGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP 787
+GG +T +IV++R + +W ++ +T+ S K+ EG YQFRI A N GV DP
Sbjct: 13110 DGGSEITNYIVDKRETSRPNWAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDP 13168
Query: 788 LETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNL 847
+ TE A NP +PPG P ++++TK+ +T++W P DGG+P+ GY++E+R+ +
Sbjct: 13169 VFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVN 13228
Query: 848 WVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
W VN+ PI GL E TEYEFRV A+NKAGPG+PS S + A+DP PPG
Sbjct: 13229 WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPA 13288
Query: 908 DLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIP--ISGTCYTVG 963
V D++ SS+SL+W +PA G P GY++E++ D+ W +C +P + T + V
Sbjct: 13289 FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRC-NLPQNLQKTRFEVT 13347
Query: 964 GLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC 1023
GL+E +Y FR+ AVN+ G +P ++ P+ +L A L+ +++RAG +
Sbjct: 13348 GLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMR 13407
Query: 1024 IHAAFSGSPPPDVIWQKDGVPTKGRETI-TKSKNHSQFL-INSTKRSDSGVYRILLQNEF 1081
++ G PPP + W K V + R + KS + FL + + D+G Y + L+N
Sbjct: 13408 LYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSC 13467
Query: 1082 GEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDAST 1139
G+ Y I V+V D P PP N+ + E ++ +TW P + + G +Y++ KRDA
Sbjct: 13468 GKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTW--EPPIIDGGSPIINYVVQKRDAER 13525
Query: 1140 ATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+W T + V L G+ Y+FRV A NE G +P ++RD
Sbjct: 13526 KSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRD 13571
Score = 372 bits (954), Expect = e-102
Identities = 280/973 (28%), Positives = 457/973 (46%), Gaps = 72/973 (7%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRM 317
P + W+K EPL+ + +V++ T +L I N +D G Y++ S G
Sbjct: 18034 PRPNISWVKDGEPLK---QTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATE 18090
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVW--KFNGKELKRDDKYEI 375
+ + VL++P +G PV+ E +A F + +S + P + + + +++ D
Sbjct: 18091 NLSVIVLEKPGPPVG---PVRFDE-VSADFVV-ISWEPPAYTGGCQISNYIVEKRDTTTT 18145
Query: 376 T---VSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKA-----QLTIDRIPIK------- 420
T VS T+KI + +F A N K+ + I + P K
Sbjct: 18146 TWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGT 18205
Query: 421 -FVSNLKNVR--------VKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMN--H 468
FV+++ + V + + L K+ ++ W K + + TK+
Sbjct: 18206 PFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLD 18265
Query: 469 EGKRAELIIEDAQLSDGGEYT-----VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
EG E + + G+ + VA DP ++T K D
Sbjct: 18266 EGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYD- 18324
Query: 524 HAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVH--KLIFPSMGPEHEG 581
GS +V + +G W+K T++ + G V + F + G
Sbjct: 18325 ---GGSKITGYIVEKKDLPDGRWMK--ASFTNVLETEFTVSGLVEDQRYEFRVIARNAAG 18379
Query: 582 KYTFRAKGTESEASVFIADPP--TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKV 639
++ + + + + D P ++DP + + HA G T ++ RGKP+P V
Sbjct: 18380 NFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA-----GETFVLEADIRGKPIPDV 18434
Query: 640 TWYKDGMEVTE-EERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVL 698
W KDG E+ E R+ ++ + L + +C+R D G +LKL N G+ + + + VL
Sbjct: 18435 VWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVL 18494
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
DRP PP+G ++ ++ ++ W P +GG ++ +I+E+R + SW ++ + +
Sbjct: 18495 DRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQV-STEVQA 18553
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAV 818
N+ K+ G Y FR++AVN G+ +PLE+ V A NP +PPG S P+V+ +TK+++
Sbjct: 18554 LNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSM 18613
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
+TW P DGG + GYI+E+R K W NK + + V GL E YEFRV A
Sbjct: 18614 VVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAA 18673
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYI 936
N AG G+PS PS A D + PPG + V+D+S SS+SLAW +P G P GY+
Sbjct: 18674 ENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYV 18733
Query: 937 LEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRA 995
+E++ EW+ CT + G +TV L E +Y FRI A+N GVGEP L V A
Sbjct: 18734 VEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVA 18793
Query: 996 MPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKGRETITKS 1054
P+ +L A L+ +V+RA L + G P P+V W+K +G+ T R I +
Sbjct: 18794 QERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT-DRAQIEVT 18852
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+ + +I++ R DSG Y + L+N G ++VRV D P P NL + E ++VTL
Sbjct: 18853 SSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTL 18912
Query: 1115 TWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVAR 1172
+W P + + G +YI+ KR+ + + T + + L G YYFRV+A
Sbjct: 18913 SW--EPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLAS 18970
Query: 1173 NEIGDSEPLDSRD 1185
NE G P ++ +
Sbjct: 18971 NEYGIGLPAETTE 18983
Score = 369 bits (946), Expect = e-101
Identities = 203/577 (35%), Positives = 321/577 (55%), Gaps = 11/577 (1%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ + G + ++ GKP P + WYKD E+ V +E D A + I + R +SG
Sbjct: 20577 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20636
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
LKL+N GSA+AT+ + +LD+P PP G +EF ++ + + W+ P D+GG +T +
Sbjct: 20637 CYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHY 20696
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
IVE+R + W + E + +T K+ +G Y FR+ AVN G+ +PLE++ V A
Sbjct: 20697 IVEKRETSRVVWSMVSEHLEECI-ITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAK 20755
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N PG P+VT +TK ++T+ W+ P DGG+ + GY +E+R K S W V K+ I
Sbjct: 20756 NAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETI 20815
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ T+ V GL E+++Y++RV AVN AG G S PS A DP+ PPG + ++DS+
Sbjct: 20816 RDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 20875
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSK-CTKIPISGTCYTVGGLIERQKYFF 973
SSI+L W +P G +GY++E+R + +EW+ TK + T Y V L Y+F
Sbjct: 20876 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 20935
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
R+ AVN AG GEP+E+++ V+A AP+ DL L++ ++ +AG + + F G PP
Sbjct: 20936 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPP 20995
Query: 1034 PDVIWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYD-IHV 1090
P V W+KD + + R +I + + S I R+D+G Y + ++N GE + + V
Sbjct: 20996 PTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSV 21055
Query: 1091 RVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAER 1148
+V D P L++ TVTL W+ P + + G +Y+I KRDA+ TW + +
Sbjct: 21056 KVLDTPAACQKLQVKHVSRGTVTLLWD--PPLIDGGSPIINYVIEKRDATKRTWSVVSHK 21113
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
S + + L ++FRV+A NEIG EP ++ +
Sbjct: 21114 CSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTE 21150
Score = 361 bits (927), Expect = 2e-99
Identities = 200/602 (33%), Positives = 315/602 (52%), Gaps = 12/602 (1%)
Query: 590 TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVT 649
+ES + + D +++ I VK G I G+PLP ++W KDG+E+
Sbjct: 19467 SESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE 19526
Query: 650 EEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVE 709
E R + ++ LLT+ +C+R D+G +L LKN G+ + ++ VLD+P PP G +E
Sbjct: 19527 ERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLE 19586
Query: 710 FLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEG 769
L+ + W P+++GG + +IVE+R +W I E + ++T+ K+ +G
Sbjct: 19587 INGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT-ICEGELQMTSCKVTKLLKG 19645
Query: 770 KAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDG 829
Y FR+ VN GV +PLE+ + A +P P + ++T VTKE++T+ W+ P DG
Sbjct: 19646 NEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDG 19705
Query: 830 GAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSV 889
G+ + GYI+ERR+K S WV VNK P+ + GL E EYE+RV A N AG PS
Sbjct: 19706 GSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSE 19765
Query: 890 PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEW 947
S + A+DPV P + DS ++I++AW +P G P +GY +E + D +W
Sbjct: 19766 TSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW 19825
Query: 948 SKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLS 1007
K + + GT YT+ GL +Y FR+++VN+ G +P + A P FD+
Sbjct: 19826 -KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDID 19884
Query: 1008 ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKR 1067
+ ++ ++V+AG + + F G P P+V+W K + R + + + + I + R
Sbjct: 19885 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANR 19944
Query: 1068 SDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQE-DG 1126
+DSG Y + +QN A + V+V D P PPTN+ + + + L+W DV E DG
Sbjct: 19945 NDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSW----DVPENDG 20000
Query: 1127 EA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
A +Y I KR+AS W + Y VT L G YYFRV NE G P ++
Sbjct: 20001 GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAET 20060
Query: 1184 RD 1185
++
Sbjct: 20061 KE 20062
Score = 358 bits (918), Expect = 2e-98
Identities = 222/650 (34%), Positives = 334/650 (51%), Gaps = 19/650 (2%)
Query: 552 EITDLPGMQIVKQGAVH--KLIFPSMGPEHEGKYTFR--AKGT--------ESEASVFIA 599
E DLP +K V+ + F GKY FR AK T ES ++
Sbjct: 14006 EKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICK 14065
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIK-VPFRGKPLPKVTWYKDGMEVTEEERVSMER 658
D VL+ +T+K G T + + GKPLPK +W K G ++ + +
Sbjct: 14066 DEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITS 14125
Query: 659 GEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCV 718
++LTI R+D+G + N G+ + ++VLD P PP G VE +S
Sbjct: 14126 TPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKA 14184
Query: 719 HMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILA 778
+ W P ++GG P+ +I+E+R + W + E D + K+ +G Y FR+ A
Sbjct: 14185 TLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSE-DIQSCRHVATKLIQGNEYIFRVSA 14243
Query: 779 VNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
VN G +P+++E V + PPG +P+V++VTK T++W P DGG+ + GY V
Sbjct: 14244 VNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14303
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
ERR+K S WV K P+ +C V GL E + YEFRV A N+AG G PS S SV+ KD
Sbjct: 14304 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14363
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPPSGYILEMRAEDTKEWSK-CTKIPI 955
PPG + HV+D++ S SLAW +P G +GY++E + + W K T +
Sbjct: 14364 AAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTAL 14423
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
T + V L ++KY FRI A+N+AGVGEP + V + AP F+L A L+ +V
Sbjct: 14424 RITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI-PDVEIVEREMAPDFELDAELRRTLV 14482
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
VRAG ++ I G P P+V W KD + K R I +++ + +I R D+G + +
Sbjct: 14483 VRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 14542
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
++N G+ ++VRV D P P NLR + ++VTL W+ +YI+ KR
Sbjct: 14543 TIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKR 14602
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+A+ ++ TA + Y VTGL G +Y+FRV+A NE G EP ++ +
Sbjct: 14603 EATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTE 14652
Score = 355 bits (910), Expect = 2e-97
Identities = 278/985 (28%), Positives = 444/985 (45%), Gaps = 97/985 (9%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P + W K PL+ + D + T L I + +D G Y ++V G K
Sbjct: 16952 PKPTITWTKDGLPLKQTTRINVTDSLDLTT---LSIKETHKDDGGQYGITVANVVGQKTA 17008
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKF---NGKELKRDDKYE 374
S E+ LD+P G PVK + + I LS P + N KRD
Sbjct: 17009 SIEIVTLDKPDPPKG---PVKFDD--VSAESITLSWNPPLYTGGCQITNYIVQKRDTTTT 17063
Query: 375 I--TVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV-QKAQLTIDRIPIKF---------- 421
+ VS TLK+ + +F A N Q L D I ++
Sbjct: 17064 VWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGT 17123
Query: 422 -----VSNLKNV-----RVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEG 470
+S V V + L K+ ++ W K + ++H T++ +
Sbjct: 17124 PFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQN-- 17181
Query: 471 KRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMS-DVHAATGS 529
L +G EY Y+ IV V + + ++ D G+
Sbjct: 17182 -----------LEEGIEYEF---------RVYAENIVGVGKASKNSECYVARDPCDPPGT 17221
Query: 530 PAELCVVLNDEKVEGVWLKD----GKEIT-------DLPGMQIVKQGAVHKLI--FPSMG 576
P + V N+ ++ W K G IT DLP + +K + + F G
Sbjct: 17222 PEPIMVKRNEITLQ--WTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSG 17279
Query: 577 PEHEGKYTFR----------AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAH 626
+ +Y FR +K ++S + D + ++ I V G T
Sbjct: 17280 LTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFR 17339
Query: 627 IKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDH 686
++ GKPLP + W + E+ E R ++ + +ALL + + +R D G +L+ N
Sbjct: 17340 LEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA 17399
Query: 687 GSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKK 746
GS + +++ VLDRP PP+G V+ ++ + W P +GG ++ ++VE+R +
Sbjct: 17400 GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRL 17459
Query: 747 SWIKIGEVDGKVTN-FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFA 805
+W + VTN K+ EG Y FRI+AVN GV +PLE+ V NP PG
Sbjct: 17460 AWTVVASE--VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPP 17517
Query: 806 SQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDG 865
+VT++ K+++T+ WN P DGG+ ++GYIVE+R + W+ NK I + V G
Sbjct: 17518 KSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTG 17577
Query: 866 LLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWRE 925
L ED EYEFRV A N AG G+PS + A DPV PG + H+ D++ +SI+LAW +
Sbjct: 17578 LTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGK 17637
Query: 926 PA--EGDPPSGYILEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAG 982
P G GY++E+ D +EW T + + T + + L E Q+Y R+ A+N+ G
Sbjct: 17638 PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVG 17697
Query: 983 VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG 1042
+GE + V+ AP+ DL + L+ +VVRAG + IH F G P P++ W ++
Sbjct: 17698 LGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREE 17757
Query: 1043 VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNL 1102
+ I K N++Q I++ R+D+G Y + L+N G + V+V D P PP NL
Sbjct: 17758 GEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNL 17817
Query: 1103 RLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLL 1160
+ E ++ L W P + + G +Y+I KR+++ + + + + V L
Sbjct: 17818 AVKEVRKDSAFLVW--EPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLT 17875
Query: 1161 PGRKYYFRVVARNEIGDSEPLDSRD 1185
G YYFRV+A NE G P+++ D
Sbjct: 17876 EGAIYYFRVMAENEFGVGVPVETVD 17900
Score = 352 bits (902), Expect = 2e-96
Identities = 208/628 (33%), Positives = 317/628 (50%), Gaps = 22/628 (3%)
Query: 580 EGK-YTFRA-------KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPF 631
EGK YTFR +GT SE +V D L+ L K +K+P
Sbjct: 13642 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13701
Query: 632 RGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATA 691
+GKP P V+W K + + RVS+E L + +C + D+G + LKN G+
Sbjct: 13702 KGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEG 13761
Query: 692 TLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKI 751
T+ + V+ +P P G ++F E++ + +KW PKD+GG +T +I+E+R W+
Sbjct: 13762 TISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTC 13821
Query: 752 GEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVT 811
K T F ++ EG Y FR+ A N GV + L++E + A +P + P P +
Sbjct: 13822 ASAVQKTT-FRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIV 13880
Query: 812 DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTE 871
DV ++V++TW P + GG+P+ GY +E +++ S LW NK PI+ V GL E E
Sbjct: 13881 DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLE 13940
Query: 872 YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EG 929
YEFRV+A+N AG G+PS+PS VVA DP+ PPG + +++ + +S++L W EP G
Sbjct: 13941 YEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINI---TRNSVTLIWTEPKYDGG 13997
Query: 930 DPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVE 988
+GYI+E R +K W K + + +TV L+E KY FRIRA N AG + P E
Sbjct: 13998 HKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSE 14057
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHA-AFSGSPPPDVIWQKDGVPTKG 1047
+ + AP L +K + ++AG + ++A + G P P W K G +
Sbjct: 14058 STETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRP 14117
Query: 1048 RE--TITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLF 1105
+ IT + S I R D+G Y I N FG + V V D P PP + +
Sbjct: 14118 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEIS 14177
Query: 1106 EEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGR 1163
TLTW +P +++ G YI+ KR+ S W +E + S ++ T L+ G
Sbjct: 14178 NVSAEKATLTW--TPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGN 14235
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINK 1191
+Y FRV A N G EP+ S ++++
Sbjct: 14236 EYIFRVSAVNHYGKGEPVQSEPVKMVDR 14263
Score = 352 bits (902), Expect = 2e-96
Identities = 217/667 (32%), Positives = 334/667 (50%), Gaps = 19/667 (2%)
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAV--HKLIFPSMGPEHEGKYTF 585
GS +V E EG W+K T++ G V H+ F + G ++
Sbjct: 16162 GSKITGYIVEKKELPEGRWMK--ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSE 16219
Query: 586 RAKGTESEASVFIADPPTI--DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYK 643
++ T + + DPP I DP + + HA G + + GKP+P + W K
Sbjct: 16220 PSESTGAITARDEVDPPRISMDPKYKDTIVVHA-----GESFKVDADIYGKPIPTIQWIK 16274
Query: 644 DGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKP 703
E++ R+ ++ + L++ + VR DSG +LK KN G + T+++ VLDRP P
Sbjct: 16275 GDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP 16334
Query: 704 PQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFST 763
P+G V ++ + WK P +GG + +IVERR + W + + + + +
Sbjct: 16335 PEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV-DANVQTLSCKV 16393
Query: 764 NKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWN 823
K+ EG Y FRI+AVN GV +PLE+E V A NP P P+VT VTK+++ + W
Sbjct: 16394 TKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWE 16453
Query: 824 APTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAG 883
P DGG+ +LGY++E+R K W +K I + V GL+E+ +YEFRV A N AG
Sbjct: 16454 RPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAG 16513
Query: 884 PGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRA 941
+PS PS+ A DP+ PG + V D + SS+ L+W +P G GYI+E
Sbjct: 16514 LSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCD 16573
Query: 942 EDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPA 1000
EW+ CT I+ T V L+E+ +Y FRI A+N+AGVGE ++ +
Sbjct: 16574 VSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLE 16633
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
AP DL L+ + +RAG +L + G P P+V W K + I + + +
Sbjct: 16634 APDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSL 16693
Query: 1061 LINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
++++ R DSG Y + L+N G + VRV D P PP NL++ E ++V++TW P
Sbjct: 16694 VLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW--EP 16751
Query: 1121 DVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+ + G +YI+ KR+A+ ++ N + + L G YYFRV A NE G
Sbjct: 16752 PLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG 16811
Query: 1179 EPLDSRD 1185
P + D
Sbjct: 16812 LPAQTAD 16818
Score = 351 bits (901), Expect = 2e-96
Identities = 205/589 (34%), Positives = 309/589 (52%), Gaps = 19/589 (3%)
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKD--GMEVTEEERVSMERGEDQALL 665
VL+ + +TVK G T ++ RGKP P+V W KD ++T RV ++ D +
Sbjct: 11897 VLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKF 11956
Query: 666 TISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAP 725
+++ R D G ++ N GS A ++VLD+P P + ++ +++S + W P
Sbjct: 11957 SLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRN-LKIVDVSSDRCTVCWDPP 12015
Query: 726 KDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVS 785
+D+GG + +I+E+ + W + ++ EG Y FR+ A N G
Sbjct: 12016 EDDGGCEIQNYILEKCETKRMVWSTYSATV-LTPGTTVTRLIEGNEYIFRVRAENKIGTG 12074
Query: 786 DPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGS 845
P E++ V A + PG P+VT V+KE +T+ WN P DGG + GY +E+++K S
Sbjct: 12075 PPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 12134
Query: 846 NLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL 905
WVPVNK I + V LL D EY+FRV A N+ G G+PS+PS VVAKDP++PPG
Sbjct: 12135 TRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGP 12194
Query: 906 VQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMR-----AEDTKEWSKC-TKIPISG 957
+ V D++ SI+L W +P G P GY++EMR A + W +C +
Sbjct: 12195 PTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVR 12254
Query: 958 TCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVR 1017
+TV L E Q+Y FR+ A N+ G+G P EL + ++ P+ DL A ++ ++VR
Sbjct: 12255 KEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVR 12314
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLI--NSTKRSDSGVYRI 1075
AG + + A G P P V W+K G+ R+ + FL+ NST R DSG Y +
Sbjct: 12315 AGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNST-RDDSGKYSL 12373
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIM 1133
L N GE ++VRV D P P ++L++ + + ++W +P + G HYI+
Sbjct: 12374 TLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSW--APPENDGGSQVTHYIVE 12431
Query: 1134 KRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
KR+A TW T V + VT L+PG +YYFRV A NE G P D
Sbjct: 12432 KREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTD 12480
Score = 348 bits (892), Expect = 3e-95
Identities = 218/651 (33%), Positives = 325/651 (49%), Gaps = 40/651 (6%)
Query: 581 GKYTFRAKGTES------EASVFIAD------PPTIDPSVLEALAAHAITVKVGHTAHIK 628
G+Y FR K + A+V D PP+ID + V+ G +I
Sbjct: 9780 GEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSID-------LKEFMEVEEGTNVNIV 9832
Query: 629 VPFRGKPLPKVTWYK------DGME-VTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
+G P P +TW+K D E V + V+ +D L I R D+GL +
Sbjct: 9833 AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTIT 9892
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
N+ G+A+ + L+VL RP PP G ++F +S + + W PKD+GG +T +++E+R
Sbjct: 9893 AVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKR 9952
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
+K+W+ + + K ++ K+ EG Y FRI+A N G+ +PL++E A N
Sbjct: 9953 EANRKTWVHVSS-EPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSV 10011
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQ---- 857
PG +P V+ VT+ ++T+ W P DGG+PV GY +E + S W VN+DPI+
Sbjct: 10012 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 10071
Query: 858 GTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNS 917
G V GL+E ++Y+FRV A+N AG G S+PS A+DP+ PPG V+D + S
Sbjct: 10072 GVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKS 10130
Query: 918 SISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRI 975
S L W P + G +GYI+E + E +EW K + GT V GL E Y FR+
Sbjct: 10131 SADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRV 10190
Query: 976 RAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD 1035
RAVN AG+GEP E+ + +P L A ++ +VV AG + I A SG PPP
Sbjct: 10191 RAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPT 10250
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADF 1095
V W + TI + S +I + +RS GVY +L +NE GE + I V V D
Sbjct: 10251 VTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDV 10310
Query: 1096 PRPPTNLRLFEEVPN-TVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKY 1154
P P L + N + LTW D +Y+I KR++ W V
Sbjct: 10311 PGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA 10370
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINK-----DQIQDLSAK 1200
TV GL+ G+ Y+FR+ A N IG +++ + +I + ++ +DL K
Sbjct: 10371 TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVK 10421
Score = 348 bits (892), Expect = 3e-95
Identities = 210/595 (35%), Positives = 309/595 (51%), Gaps = 17/595 (2%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
IA TI PS+ L + +++ G I++P G+P P ++W KDG + + RV++E
Sbjct: 17999 IAKDLTIQPSL--KLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE 18056
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSC 717
+L I ++D G + N G+AT L + VL++P PP G V F E+S
Sbjct: 18057 ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADF 18116
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
V + W+ P GG ++ +IVE+R +W + + T K++ G YQFRI
Sbjct: 18117 VVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT-IKITKLKTGTEYQFRIF 18175
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYI 837
A N G S PL+++ V P + PG P VT ++K+ + + W+ P DGG ++GY
Sbjct: 18176 AENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYH 18235
Query: 838 VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAK 897
+E+++K S LWV +NK PIQ TK GL E EYEF+V A N G G+PS S VA+
Sbjct: 18236 LEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVAR 18295
Query: 898 DPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPI 955
DP PPG + + + + ++++L W++PA G +GYI+E + W K + +
Sbjct: 18296 DPCDPPGRPEAIVI---TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 18352
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
T +TV GL+E Q+Y FR+ A N AG EP + + A AP L + K +
Sbjct: 18353 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVI 18412
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSG 1071
VV AG + A G P PDV+W KDG T R I + + ++ R+D G
Sbjct: 18413 VVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGG 18472
Query: 1072 VYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGE--A 1128
Y + L N G I V+V D P PP L++ L WN P +Q+ G +
Sbjct: 18473 QYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN--PPLQDGGANIS 18530
Query: 1129 HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
HYII KR+ S +W + V + Y VT LLPG +Y FRV+A N+ G EPL+S
Sbjct: 18531 HYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLES 18585
Score = 345 bits (885), Expect = 2e-94
Identities = 290/986 (29%), Positives = 433/986 (43%), Gaps = 117/986 (11%)
Query: 268 WIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEP 327
WIK T ++ + Q KY IS +N DAG VG+ + ++ +++
Sbjct: 14414 WIKDTTGTALRITQFVVPDLQTKEKYNFRISAIN--DAG-----VGEPAVIPDVEIVER- 14465
Query: 328 LKFLGEMKP---VKVTERQTAVFEIRLS---------KKEPNFVWKFNGKELKRDDKYEI 375
EM P + R+T V LS + P W + LK E
Sbjct: 14466 -----EMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIEN 14520
Query: 376 TVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSR 435
T S L I + D+G+F +TI+ P S NVRV +
Sbjct: 14521 TESFT----LLIIPECNRYDTGKFV-----------MTIEN-PAGKKSGFVNVRVLDTPG 14564
Query: 436 ACLEC---ELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRA--------------ELIIE 478
L ++T VTL W D L+ G++ + KR + +
Sbjct: 14565 PVLNLRPTDITKDSVTLHW--DLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 14622
Query: 479 DAQLSDGGEYTVVAMQD-----GDPTEYYSTAIVTVEERLATVKS-GMSDVHAAT----- 527
LS+G EY M + G+PTE +T V E + S + D+ +T
Sbjct: 14623 VTGLSEGCEYFFRVMAENEYGIGEPTE--TTEPVKASEAPSPPDSLNIMDITKSTVSLAW 14680
Query: 528 -------GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHE 580
GS V+ K W IT + G++ V + G E
Sbjct: 14681 PKPKHDGGSKITGYVIEAQRKGSDQWT----HITTVKGLECVVRNLTE-------GEE-- 14727
Query: 581 GKYTFRAKGTES-------EASVFIADPPTIDPSV-LEALAAHAITVKVGHTAHIKVPFR 632
YTF+ S E+ I T+ P + L + + K G +++P
Sbjct: 14728 --YTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVL 14785
Query: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
G+P P VTW K + + +RV+ E +L I+ CVR DSG L +N G
Sbjct: 14786 GRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDV 14845
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
+ + V D P PP G ++F E+S V W P+++GG P++ ++VE R +W+++
Sbjct: 14846 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELA 14905
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTD 812
+ T + ++ G YQFR+ A N GV + + + A P + PG PQVT
Sbjct: 14906 TTVIRTT-YKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14964
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
VTK+++TI+W+ P DGG+P+LGY VER+++ LW V+K + G GL + Y
Sbjct: 14965 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAY 15024
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGD 930
EFRVIA N AG +PS PS ++A DP+ PPG L++ + +++L W +P G
Sbjct: 15025 EFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNI---TRHTVTLKWAKPEYTGGF 15081
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVEL 989
+ YI+E R W K I +TV GL E Y FR+ A N AG + P E
Sbjct: 15082 KITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEP 15141
Query: 990 DKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE 1049
+ APK + + K ++++AG A + A SG PPP + W KDG +G
Sbjct: 15142 SDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTA 15201
Query: 1050 TI-TKSKNHSQFLIN-STKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFE 1106
+ K + S L+N + R DSG Y + N G A++ +V+V D P PP L + E
Sbjct: 15202 KLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTE 15261
Query: 1107 EVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRK 1164
L+W P + + G HYI+ KR+ S W A V K VT LL G +
Sbjct: 15262 VTSEKCVLSW--FPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNE 15319
Query: 1165 YYFRVVARNEIGDSEPLDSRDTWLIN 1190
Y FRV+A N+ G EPL+S +N
Sbjct: 15320 YIFRVMAVNKYGVGEPLESEPVLAVN 15345
Score = 341 bits (874), Expect = 3e-93
Identities = 190/575 (33%), Positives = 298/575 (51%), Gaps = 8/575 (1%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ +K G ++ G+P P + W KDG E+ ++ ++ + L + R DSG
Sbjct: 15166 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15225
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
L N G A ++ VLDRP PP+G + E++ + W P D+GG + +
Sbjct: 15226 AYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY 15285
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
IV++R + +W + + +VT K+ +G Y FR++AVN GV +PLE+E V A
Sbjct: 15286 IVQKRETSRLAWTNVAS-EVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAV 15344
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
NP PP P+VT +TK+++ + W P DGG+ ++ YIVERR K W+ NK +
Sbjct: 15345 NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTL 15404
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ V GL E EYEFR++A N AG PS S A D V PG + V D+S
Sbjct: 15405 TDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSR 15464
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFF 973
SSIS+AW +P G +GY++E+ + EW T + T YT+ GL E Q+Y
Sbjct: 15465 SSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKI 15524
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
RI A+N G+GEP + +A P+ +L A L+ + +RA L + G P
Sbjct: 15525 RIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPA 15584
Query: 1034 PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVA 1093
P+V W +D + + +I + +++ ++ + R DSG Y + ++N G ++VRV
Sbjct: 15585 PEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVL 15644
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFS 1151
D P PP +L++ E +VTLTW+ P + + G +YI+ KR+++ + T A
Sbjct: 15645 DTPGPPQDLKVKEVTKTSVTLTWD--PPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHK 15702
Query: 1152 NKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDT 1186
+ V L G YYFRV+A NE G P ++ ++
Sbjct: 15703 TSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAES 15737
Score = 340 bits (872), Expect = 5e-93
Identities = 197/589 (33%), Positives = 296/589 (50%), Gaps = 11/589 (1%)
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
PP+++ L+ + VK G T RG P+P W DG E+ +E ++E
Sbjct: 11202 PPSVE---LDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11258
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHM 720
++LTI NC+R D+G + + N GS T +HL+VLD P PP G + L+++ + +
Sbjct: 11259 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 11318
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W+ PKD+GG PV +IVE++ K +W + K T +++G Y FR+ A N
Sbjct: 11319 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-TKLKIPHLQKGCEYVFRVRAEN 11377
Query: 781 SEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVER 840
GV PL++ A + PP +P VTD+T+ A T++W P DGG+P+ GY +ER
Sbjct: 11378 KIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMER 11437
Query: 841 RKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPV 900
R+ + WV VNK PI K V GL E YEFRV A N AG +PS S + A P+
Sbjct: 11438 REV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPI 11496
Query: 901 KPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGT 958
KPPG + + D S + L W +P G P GY++E + T +W++ K +
Sbjct: 11497 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11556
Query: 959 C-YTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVR 1017
C + V GLIE +Y FRI+A N G GEP EL + V A P+ +L + + VR
Sbjct: 11557 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVR 11616
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
G + I A G P PD+ W K+G + + R + + + I R+D G Y I
Sbjct: 11617 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYII 11676
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
+N G A+ V V D P P NL++ T++W + D ++I+ R
Sbjct: 11677 SAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR 11736
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ W A V + + LL +YYFRV A N++G ++++
Sbjct: 11737 KPNQKGWSIVASDV-TKRLIKANLLANNEYYFRVCAENKVGVGPTIETK 11784
Score = 335 bits (859), Expect = 2e-91
Identities = 196/574 (34%), Positives = 306/574 (53%), Gaps = 14/574 (2%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE--DQALLTISNCVRED 674
+ +K G + IK +G+P+P+VTW+KDG+E+ E+R++ME + L + + R+
Sbjct: 21663 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEI--EKRMNMEITDVLGSTSLFVRDATRDH 21720
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
G+ ++ KN GSA A + + V D P G + F ++G + + W AP ++G P+T
Sbjct: 21721 RGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPIT 21780
Query: 735 QFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF 794
+I+E+R + +W I E + +++ K+ G YQFR+ AVN GV PL+++ V
Sbjct: 21781 HYIIEKRETSRLAWALI-EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVV 21839
Query: 795 AGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPV-NK 853
A P P+ +++T ++T+TW P DGG+ + YI+ERR+K S WV V +K
Sbjct: 21840 AQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISK 21899
Query: 854 DPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSD 913
PI T+ V GL E EYEF V+A N AG G S S + ++PV PPG + V+D
Sbjct: 21900 RPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTD 21959
Query: 914 SSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKY 971
+S +++SL W +P G GYI+EM D +W K T YTV L ++Y
Sbjct: 21960 TSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEY 22019
Query: 972 FFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGS 1031
FR+ A+N AG G+ E+ ++A+ AP+ D+ A K VVRAG ++ + A+ G
Sbjct: 22020 KFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGR 22079
Query: 1032 PPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091
P P +W K R I + + S + + R+D+G Y + ++N G V+
Sbjct: 22080 PTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVK 22139
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA---HYIIMKRDASTATWYTAAER 1148
V D P PP + + + TL W+ +P + DG A HY++ KR+AS +W +E+
Sbjct: 22140 VLDTPGPPGPITFKDVTRGSATLMWD-APLL--DGGARIHHYVVEKREASRRSWQVISEK 22196
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
+ V L G YYFRV A NE G EP +
Sbjct: 22197 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYE 22230
Score = 331 bits (849), Expect = 2e-90
Identities = 210/619 (33%), Positives = 310/619 (50%), Gaps = 26/619 (4%)
Query: 582 KYTFRAKGTESEASVFIADPPTIDPSVLEA---------LAAHAITVKVGHTAHIKVPFR 632
+Y+FR + I+DP + V+ L + TV G + VPF
Sbjct: 15811 EYSFRVSAQNEKG---ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFI 15867
Query: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
G+P P VTW+KD + + + RV+ E E+ +LLTI + RED G ++KL N G A T
Sbjct: 15868 GRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIET 15927
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
L++ VLD+P PP G V+ E++ + + W PK +GG + +IVE+R +W +
Sbjct: 15928 LNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15987
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTD 812
+ T +++ G YQFRI A N G S L +E A P + PG P VT
Sbjct: 15988 ATVARTT-IKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTL 16046
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
+++++ + WN P DGG+ V+GY +ER+++ S LWV +NK PI TK GL E EY
Sbjct: 16047 SSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEY 16106
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGD 930
EFRV A N G G+PS S VA+DP PPG + + V + +S++L W++P G
Sbjct: 16107 EFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIV---TRNSVTLQWKKPTYDGGS 16163
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV-GEPVEL 989
+GYI+E + W K + I T + V GL+E +Y FR+ A N AGV EP E
Sbjct: 16164 KITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSES 16223
Query: 990 DKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK--DGVPTKG 1047
+ A P+ + + K +VV AG + + A G P P + W K +
Sbjct: 16224 TGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTA 16283
Query: 1048 RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEE 1107
R I + + + R DSG Y + +N GE ++V+V D P PP +
Sbjct: 16284 RLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16343
Query: 1108 V-PNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRK 1164
V TL W P +Q+ G +YI+ +R+ S W V + VT LL G +
Sbjct: 16344 VTAEKCTLAW--KPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNE 16401
Query: 1165 YYFRVVARNEIGDSEPLDS 1183
Y FR++A N+ G EPL+S
Sbjct: 16402 YTFRIMAVNKYGVGEPLES 16420
Score = 331 bits (848), Expect = 3e-90
Identities = 261/933 (27%), Positives = 421/933 (45%), Gaps = 67/933 (7%)
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEI 349
G +Y+ + +VN A S S D +++ E +EPL + + + A F +
Sbjct: 19845 GAEYVFRVKSVNKVGASDPSDS-SDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTM 19901
Query: 350 RL---SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+ + PN +W +L+ + T S LT I++A +DSG+++ N+
Sbjct: 19902 TVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLT----IENANRNDSGKYTLTIQNV 19957
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRW---KKDGQLLMHGTK 463
+ A LT+ + N+ V++ +T + L W + DG +
Sbjct: 19958 LSAASLTLVVKVLDTPGPPTNITVQD---------VTKESAVLSWDVPENDGGAPVKNYH 20008
Query: 464 YSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERL---ATVKSGM 520
K+A + + + + Y V +Q+G YY E + A K G+
Sbjct: 20009 IEKREASKKAWVSVTNN--CNRLSYKVTNLQEG--AIYYFRVSGENEFGVGIPAETKEGV 20064
Query: 521 SDVHAATGSPAELCVV-LNDEKVEGVWLK---DGK--------EITDLPGMQIVKQGAVH 568
+ P +L V ++ + V WLK DG E + VK
Sbjct: 20065 K-ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAK 20123
Query: 569 KLIFPSMGPEHEGKYTFRA-----KGTESEASVFIA-------DPPTIDPSVLEALAAHA 616
G +Y FR G + + +PP ID ++ +H
Sbjct: 20124 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID---MKNFPSHT 20180
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ V+ G + +P GKPLPKVT +DG+ + R + E + + + V D+G
Sbjct: 20181 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20240
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
+ N G+ A +++ VLDRP PP G V +++ V +KW+ PK +GG VT +
Sbjct: 20241 RYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNY 20300
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
I+ +R W ++ + T K+ G+ YQFRI A N G+SD +++ V
Sbjct: 20301 ILLKRETSTAVWTEVSATVAR-TMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVK 20359
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
P PG S P VT+VT+E++T+ W+ P +GG+ V+GY +E + + S LW NK I
Sbjct: 20360 LPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI 20419
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ T V + YEFRV A N AG G+PS PS V+A D +PP +++ ++D S
Sbjct: 20420 RTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPP---RNVRITDISK 20476
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+S+SL+W++PA G +GYI+E R W+K + ++ T + + GL + +Y FR
Sbjct: 20477 NSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFR 20536
Query: 975 IRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
+ A N G + P E+ + + P DL + RAGT++ + A SG P
Sbjct: 20537 VFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPA 20596
Query: 1034 PDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091
P + W KD + T + + + + LI R +SG Y + L+N G A I V+
Sbjct: 20597 PTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQ 20656
Query: 1092 VADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF 1150
+ D P PP F+ V +TL W D HYI+ KR+ S W +E +
Sbjct: 20657 ILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLE 20716
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
T T ++ G +Y FRV A N+ G EPL+S
Sbjct: 20717 ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 20749
Score = 330 bits (846), Expect = 6e-90
Identities = 206/622 (33%), Positives = 309/622 (49%), Gaps = 19/622 (3%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
+K+G ++ ++ +GK +F K + + PPT+ + L T++V
Sbjct: 10476 LKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELA---PPTLHLDFRDKL-----TIRV 10527
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
G + + GKP PKV+W+KD +V E++R ++ L R DSG +
Sbjct: 10528 GEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVV 10587
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
++N GS ++V+DRP PP G V F E++ + + WK P D+GG +T +I+E++
Sbjct: 10588 VENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKK 10647
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
VGK W+ + K T +K+ EGK Y FRI A N G+SDPL ++ + A +
Sbjct: 10648 EVGKDVWMPVTSASAKTT-CKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRV 10706
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG-TK 860
P QP VT+VTK++ +TWN P DGG P+ YI+E+R+ S W V KDPI TK
Sbjct: 10707 PDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTK 10765
Query: 861 CTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSIS 920
V LLE +YEFRV A N+ G G PS PS V AKDP+ P + D++ +S+
Sbjct: 10766 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10825
Query: 921 LAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPIS--GTCYTVGGLIERQKYFFRIR 976
L W+ P G GYI+E + +EW + P S T Y V GL + Q Y FR+
Sbjct: 10826 LTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVL 10885
Query: 977 AVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
AVN AG +P + + V P+ L A + ++ G L + A G P P V
Sbjct: 10886 AVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKV 10945
Query: 1037 IWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVAD 1094
W+K+ PTK R +T S+ I + D G+Y + ++N G + V V D
Sbjct: 10946 TWKKEDRDAPTKARIDVTPV--GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD 11003
Query: 1095 FPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKY 1154
P PP +L + E ++ LTW D +Y++ +RD ++A W + +
Sbjct: 11004 KPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSH 11063
Query: 1155 TVTGLLPGRKYYFRVVARNEIG 1176
L G +Y FRV A N+ G
Sbjct: 11064 FAKHLNEGNQYLFRVAAENQYG 11085
Score = 326 bits (836), Expect = 8e-89
Identities = 262/890 (29%), Positives = 401/890 (45%), Gaps = 86/890 (9%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQ 411
P VW EL DK + + G L IKDA D G + A G+ A+
Sbjct: 8829 PTKVWTKEEGEL---DKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAAR 8885
Query: 412 LTIDRIPIKFVSNLKNVRVKERSRACLECELTSKD----VT--LRWKKDGQLLMHGTKYS 465
+ + +P V +LK V V R L D +T + +KD + MH +
Sbjct: 8886 VEVFDVPGP-VLDLKPV-VTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQP 8941
Query: 466 MNHEGKRAELIIEDAQLSDGGEYT--VVAMQD---GDPTEYYSTAIV------TVEERLA 514
+ E + ++ L +G EY V+A G P E V T ERL
Sbjct: 8942 IETERSKCDI----TGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLT 8997
Query: 515 TVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPS 574
+ S + P ++G ++ K D P + V + F
Sbjct: 8998 YTERTKSTITLDWKEPRSN----GGSPIQGYIIE--KRRHDKPDFERVNKRLCPTTSFLV 9051
Query: 575 MGPEHEGKYTFRAKGT----ESEAS----VFIAD---PPTIDPSVLEALAAHAITVKVGH 623
+ Y FR K ESE S V I D PPTI + ++ I VK G
Sbjct: 9052 ENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRL--SVRGDTIKVKAGE 9109
Query: 624 TAHIKVPFRGKPLPKVTWYK---------DGMEVTEEERVSMERGEDQALLTISNCVRED 674
HI G P+PK+ W K D +++T+EE + R E + L+I VRED
Sbjct: 9110 PVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEE---VSRSEAKTELSIPKAVRED 9166
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
G + N GS +H+ V DRP PP+ + ++ ++ W AP DNGG +T
Sbjct: 9167 KGTYTVTASNRLGSVFRNVHVEVYDRPSPPRN-LAVTDIKAESCYLTWDAPLDNGGSEIT 9225
Query: 735 QFIVERRAVGKKS--WIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE 792
+++++R +K W ++ + + K+ Y+FR+ AVN G+SD ++++
Sbjct: 9226 HYVIDKRDASRKKAEWEEVTNTAVE-KRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDK 9284
Query: 793 VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW---- 848
V +P PG +P+V TK ++ ++W P +GG+P+ GY +E+R++GS W
Sbjct: 9285 VVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVS 9344
Query: 849 -VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
P+ K ++G + V LLE +Y+FR +A+N AG G PS PS VA DP+ PPG
Sbjct: 9345 RAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPS 9404
Query: 908 DLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTK-IPISGTC-YTVG 963
V D + SSISL W+ PA+ G P GYI+EM+ E T +W + + + TC V
Sbjct: 9405 CPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVP 9464
Query: 964 GLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC 1023
L E +KY FR++AVNEAG EP + + A P+ + + +V +AG+ +
Sbjct: 9465 NLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIR 9524
Query: 1024 IHAAFSGSPPPDVIWQKDGVPTKGRE----------TITKSKNHSQFLINSTKRSDSGVY 1073
I A G P P W+ DG K + + ++N S +I KRS +G Y
Sbjct: 9525 IPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKY 9584
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM 1133
I +N+ G+ + V+V D P PP +L++ + + L+W D D Y+I
Sbjct: 9585 SITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIE 9644
Query: 1134 KRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
KR W S + V LL ++Y+FRV A N G P+++
Sbjct: 9645 KRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVET 9694
Score = 326 bits (836), Expect = 8e-89
Identities = 217/659 (32%), Positives = 323/659 (49%), Gaps = 43/659 (6%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGT---------ESEASVFIADPPTIDPSVLEAL 612
V+ G +L F + +Y FR K E+ +SV I +P + L +
Sbjct: 22288 VEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGI 22347
Query: 613 AAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVR 672
IT K G I VP G+P PKVTW + M + E +RVS+ +D+ LT+ + +R
Sbjct: 22348 TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMR 22407
Query: 673 EDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRP 732
DSG L L+N G T ++ + V+ RP P G +E +S + W PKD GG
Sbjct: 22408 GDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22467
Query: 733 VTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE 792
+T +IVE+R G +W + K T + + Y FR+ + N GVS PLE+
Sbjct: 22468 ITNYIVEKRESGTTAWQLVNS-SVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAP 22526
Query: 793 VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN 852
+ A +P PP ++P+V V+ A++I W P DGG+ ++GY VE++++ + LWV N
Sbjct: 22527 IIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKEN 22586
Query: 853 KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVS 912
K P V GL+E EY+FR A+N AG + S S ++A++PV PG + V+
Sbjct: 22587 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE---VT 22643
Query: 913 DSSNSSISLAWREPA--EGDPPSGYILEMRAED---TKEWSKCTKIPISGTCYTVGGLIE 967
D + S++SL W PA G GYI+E + W KC +S +TV L E
Sbjct: 22644 DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE 22703
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP------AAPKFDLSARLKSHMV-VRAGT 1020
Y FR+ A N AGV + KG + P A PK +L ARL +V +RAG+
Sbjct: 22704 GDTYEFRVLAKNAAGV-----ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGS 22758
Query: 1021 ALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
L + AA G P P +IW K + + ++ + + +I RSDSG Y + ++
Sbjct: 22759 DLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK 22818
Query: 1079 NEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA---HYIIMKR 1135
N G + V+V D P P L + TL W+ QEDG A HYI+ +R
Sbjct: 22819 NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLP---QEDGGAEITHYIVERR 22875
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIG-----DSEPLDSRDTWLI 1189
+ S W + Y VT L+ +Y FRV A N+ G +SEP+ +R+++ I
Sbjct: 22876 ETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTI 22934
Score = 325 bits (833), Expect = 2e-88
Identities = 227/759 (29%), Positives = 365/759 (48%), Gaps = 54/759 (7%)
Query: 587 AKGTESEASVFIADPPTIDPSVLEA-LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+KG+ES V D + L+A L +T++ G + GKP PK+ W K
Sbjct: 22721 SKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22780
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
E+ E+VS++ +A I C R DSG L +KN G+ ++ + VLD P P
Sbjct: 22781 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPC- 22839
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNK 765
G++ ++ + W P+++GG +T +IVERR + +W+ I E + ++ +
Sbjct: 22840 GKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWV-IVEGECPTLSYVVTR 22898
Query: 766 VEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
+ + Y FR+ AVN G P+E+E + A N P P+ KE + I W P
Sbjct: 22899 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 22958
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKD-PIQGTKCTVDGLLEDTEYEFRVIAVNKAGP 884
DGG + Y+V++R+K S W VNKD + T+ V L+E +Y+FRV AVN AG
Sbjct: 22959 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 23018
Query: 885 GQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAE 942
+PS S+ + ++P PG V D++ SISLAW +P G GY+LEM+ +
Sbjct: 23019 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 23078
Query: 943 DTKEWSKC-TKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAA 1001
DT +W + T I T +TV L QKY FR+ AVN G+ E E + +
Sbjct: 23079 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 23138
Query: 1002 PKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
P +L+ LK + +RAG +L + + SG PPP + W K G+ R I ++++S +
Sbjct: 23139 PDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI 23198
Query: 1062 INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
++ R D+G Y I +N+ G+ + V+V D P P ++++ E ++VT+TW P
Sbjct: 23199 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITW-EIPT 23257
Query: 1122 VQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+ DG A +YI+ KR+A+ + T + Y ++GL+ G YYFRV+ N G
Sbjct: 23258 I--DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23315
Query: 1179 EPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLG 1238
EP ++ D L+++ PL P L D T + L
Sbjct: 23316 EPCETSDAVLVSE-------------------------VPLVP-AKLEVVDVTKSTVTLA 23349
Query: 1239 NPRPTVTLYKGDVNIT--------ANSKFWYNSTSGVCTLVIPTCTLKDSGD---YSVLV 1287
+P LY G +T A ++ W + T++ T T + G+ + +
Sbjct: 23350 WEKP---LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRA 23406
Query: 1288 ENELGKDRSSCTLTVYDKDDKSVVASI-TESLQKKSKHL 1325
+NE G T+T D V+ +I ++ +K+ H+
Sbjct: 23407 QNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHV 23445
Score = 325 bits (832), Expect = 2e-88
Identities = 195/607 (32%), Positives = 305/607 (50%), Gaps = 16/607 (2%)
Query: 592 SEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE 651
S A +A I+P V A ++++ V+VG I+VP G+P P +TW KDG+ + +
Sbjct: 16911 SLAVPIVAKDLVIEPDVKPAFSSYS--VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQT 16968
Query: 652 ERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFL 711
R+++ D L+I ++D G + + N G TA++ + LD+P PP+G V+F
Sbjct: 16969 TRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFD 17028
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKA 771
++S + + W P GG +T +IV++R W + + T K++ G
Sbjct: 17029 DVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT-LKVTKLKTGTE 17087
Query: 772 YQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA 831
YQFRI A N G S LE++ + A P + PG P T ++K+++ I W+ P +GG+
Sbjct: 17088 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 17147
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
PV+GY +ER+++ S LW VNK I T+ L E EYEFRV A N G G+ S S
Sbjct: 17148 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 17207
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSK 949
VA+DP PPG + + V + I+L W +P G +GYI+E R W K
Sbjct: 17208 ECYVARDPCDPPGTPEPIMV---KRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMK 17264
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSA 1008
+ + T +TV GL E Q+Y FR+ A N AG + +P + + A P+ +
Sbjct: 17265 ASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP 17324
Query: 1009 RLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTK 1066
+ + +VV AG + A G P P + W + + R I + + ++
Sbjct: 17325 KFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAI 17384
Query: 1067 RSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQED 1125
R D G Y + N G + ++V+V D P PP +++ +LTW SP +Q+
Sbjct: 17385 RIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW--SPPLQDG 17442
Query: 1126 GE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
G +HY++ KR+ S W A V +N VT LL G +Y FR++A N+ G EPL+S
Sbjct: 17443 GSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLES 17502
Query: 1184 RDTWLIN 1190
+ N
Sbjct: 17503 APVLMKN 17509
Score = 318 bits (816), Expect = 2e-86
Identities = 196/641 (30%), Positives = 304/641 (47%), Gaps = 25/641 (3%)
Query: 557 PGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEA--------SVFIADPPTIDPSV 608
P + + V L G + KY FR + V+ A + P +
Sbjct: 12538 PADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI 12597
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L IT+K G I+ GKP P W K EV +++ + + ++L I
Sbjct: 12598 L---MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 12654
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
+ R+DSG L +N G+ T + + V+D P PPQ + ++ + W P ++
Sbjct: 12655 DVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLED 12714
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG +T +IVE+ V + W+ K T+ K+ G+ Y FR+ A N G+S+PL
Sbjct: 12715 GGSNITNYIVEKCDVSRGDWVTALASVTK-TSCRVGKLIPGQEYIFRVRAENRFGISEPL 12773
Query: 789 ETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW 848
+ ++ A P P +VT V K+ + + W+ P DGG+P++GY++ER+++ S LW
Sbjct: 12774 TSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLW 12833
Query: 849 VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQD 908
V N ++ T+ GL+E EY FR+ A+NKAG PS P+ V A+ PV PPG +
Sbjct: 12834 VKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPE- 12892
Query: 909 LHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIP--ISGTCYTVGG 964
V D + S++SL W P G GY +E +W +C P I YT G
Sbjct: 12893 --VIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATG 12950
Query: 965 LIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCI 1024
L E+ +Y FR A + P E V + P+ DLS +KS + V+AGT +C+
Sbjct: 12951 LEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 13010
Query: 1025 HAAFSGSPPPDVIWQKDGVPTKGRETI--TKSKNHSQFLINSTKRSDSGVYRILLQNEFG 1082
A G P P V W+KDG K E I +N + S R DSG Y I +N G
Sbjct: 13011 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 13070
Query: 1083 EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTA 1140
I ++V D P PP ++++ + + L+W P +++ G +YI+ KR+ S
Sbjct: 13071 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSW--EPPLEDGGSEITNYIVDKRETSRP 13128
Query: 1141 TWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPL 1181
W + V +V L+ G +Y FR+ A N+ G +P+
Sbjct: 13129 NWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPV 13169
Score = 317 bits (812), Expect = 5e-86
Identities = 193/605 (31%), Positives = 291/605 (48%), Gaps = 26/605 (4%)
Query: 598 IADPPTIDPSVLEALA-----------AHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
++DP TI P ++ L +TV++GH H+++P++GKP P ++W KDG+
Sbjct: 21238 LSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGL 21297
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
+ E E V + E++ L+I N +E G + L N + + L P P+G
Sbjct: 21298 PLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKG 21357
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
+ F E+ V + W P+DNGG +T + +E+R + +W + + T N V
Sbjct: 21358 PIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLV 21417
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
++ + YQFR+ A N GVS PL + + A + PG +P + +VT + +++TW+AP
Sbjct: 21418 KDAE-YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPV 21476
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQ 886
DGG+ V G+ VE++++ S LW VN PI G + GL+E +Y+FRV A N AG
Sbjct: 21477 YDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSS 21536
Query: 887 PSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDT 944
PS PS +A PV PPG + D + +I+L W P G GY +E R +
Sbjct: 21537 PSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKR-QGN 21592
Query: 945 KEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG-VRAMPPPAAPK 1003
+ W +C +S YTV GL +Y FRI A N G P G + P
Sbjct: 21593 ERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPI 21652
Query: 1004 FDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRET--ITKSKNHSQFL 1061
+ +++++G +L I A G P P V W KDGV + R IT +
Sbjct: 21653 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 21712
Query: 1062 INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+ R GVY + +N G A+ +I V+V D P F + W +P
Sbjct: 21713 VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAP- 21771
Query: 1122 VQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
DG A HYII KR+ S W ++ + YT L+ G +Y FRV A N+ G
Sbjct: 21772 -LNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 21830
Query: 1179 EPLDS 1183
PLDS
Sbjct: 21831 RPLDS 21835
Score = 313 bits (801), Expect = 9e-85
Identities = 262/892 (29%), Positives = 399/892 (44%), Gaps = 90/892 (10%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTID 415
P W +GKE+K D+ +T+ D ++ L++ + +D+G ++ N + A +I+
Sbjct: 8111 PTVSWHKDGKEVKASDR--LTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 8168
Query: 416 RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAEL 475
I K+++ + +++ C+LT + DG + G+R +
Sbjct: 8169 VKVIGLPGPCKDIKASDITKS--SCKLTWEPPEF----DGGTPILHYVLERREAGRRTYI 8222
Query: 476 IIEDAQ---------LSDGGEY--TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524
+ + L GEY V A+ EY + + DV
Sbjct: 8223 PVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8282
Query: 525 AATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVK---------QGAVHKLIFPSM 575
+ + + +G G +I +I K + V L + +
Sbjct: 8283 VHNPTAEAMTITWKPPLYDG-----GSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAK 8337
Query: 576 GPEHEGKYTFRAKGTESEASVFI---ADPPT--IDP-SVLEALAAHAITVKVGHTAHIKV 629
G E +Y FR + E+ A + A PPT +DP + + ++ VK G +
Sbjct: 8338 GLEEGKEYQFRVRA-ENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDA 8396
Query: 630 PFRGKPLPKVTWYKDGM--------------------EVTEEE--------RVSME---R 658
G P P +TW KD EV EEE R+S++ +
Sbjct: 8397 SISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKK 8456
Query: 659 GEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCV 718
GE Q L + + +R D GL ++K++NDHG A A +SVLD P PP V F ++ + V
Sbjct: 8457 GESQ--LRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFV-FEDIRKTSV 8513
Query: 719 HMKWKAPKDNGGRPVTQFIVERRAVGK--KSWIKIGEVDGKVTNFSTNKVEEGKAYQFRI 776
KW+ P D+GG + + +E++ K WI + + +S K+ EGK Y FR+
Sbjct: 8514 LCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTL-RHCKYSVTKLIEGKEYLFRV 8572
Query: 777 LAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGY 836
A N G P ++ + A +P PP +P V DVT ++ + WN P +D G+P+LGY
Sbjct: 8573 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEP-KDNGSPILGY 8631
Query: 837 IVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVA 896
+E+R+ S W VNK + K VDGLLE Y FRV A N AGPG+ S PS A
Sbjct: 8632 WLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTA 8691
Query: 897 KDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIP 954
DP+ PPG V+D+S+++I L W PA G GY ++ + T EWS+CT+
Sbjct: 8692 HDPISPPG-PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 8750
Query: 955 ISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
I YTV + E Y R+ AVN AG G P E + V P P +L +K +
Sbjct: 8751 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE-TQPVTVAEPQEPPAVELDVSVKGGI 8809
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
+ AG L I A +G P P +W K +G K R I S+ +I R D G Y
Sbjct: 8810 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 8869
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---Y 1130
I N G V V D P P +L+ L W+ D ++DG + +
Sbjct: 8870 VITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWS---DPEDDGGSEITGF 8926
Query: 1131 IIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
II ++DA TW E S K +TGLL G++Y FRV+A+N+ G P++
Sbjct: 8927 IIERKDAKMHTWRQPIETERS-KCDITGLLEGQEYKFRVIAKNKFGCGPPVE 8977
Score = 308 bits (790), Expect = 2e-83
Identities = 202/595 (33%), Positives = 288/595 (48%), Gaps = 19/595 (3%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
IA I PSV L H VK I VPF+G+P V W KDG + E RV++
Sbjct: 19082 IARDIEIKPSV--ELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVS 19139
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSC 717
+ L+I +ED G L + N GS T + + VLDRP PP G + E+S
Sbjct: 19140 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDS 19198
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
+ + W P+ +GG ++ +IVE++ +W + + + T+ ++ G YQFR+
Sbjct: 19199 ITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVAR-TSIKIVRLTTGSEYQFRVC 19257
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYI 837
A N G S E+ V A P PPG P+V TK + +TW P DGG+ V+GY
Sbjct: 19258 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 19317
Query: 838 VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAK 897
+E +++ S LW NK I T+ V GL E YE+RV A N AG G+ S V A+
Sbjct: 19318 LEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPAR 19377
Query: 898 DPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPPSGYILEMRAEDTKEWSKCTKIPI 955
DP PPG + V++ + S+SL W +P G +GYI+E R W KC I
Sbjct: 19378 DPCDPPGQPE---VTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNI 19434
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEA-GVGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
T + V L E Q+Y FR+ A N A V EP E + P+ + + + +
Sbjct: 19435 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVI 19494
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGV 1072
VV+AG L I+A +G P P + W KDG + + R I + NH+ + R D+G
Sbjct: 19495 VVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQ 19554
Query: 1073 YRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGEA--- 1128
Y + L+N G ++ +V D P PP L + +L+W QEDG A
Sbjct: 19555 YVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRP---QEDGGADID 19611
Query: 1129 HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+YI+ KR+ S W + VT LL G +Y FRV N+ G EPL+S
Sbjct: 19612 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLES 19666
Score = 293 bits (751), Expect = 6e-79
Identities = 187/608 (30%), Positives = 301/608 (49%), Gaps = 25/608 (4%)
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
++ TE +V + P I L+ +TVK G + GKP PK+TW K M
Sbjct: 7368 SRPTEEIQAVDTQEAPEI---FLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM 7424
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
+ +++R+++E ++ +TI + R D+G +++ N G ATA + ++VLD+P PP
Sbjct: 7425 ILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAA 7484
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
+ +++ + W P+D+GG +T ++VERRA + W K+ K TNF K+
Sbjct: 7485 -FDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTV-KDTNFKATKL 7542
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
K Y FR+ A N GV +P++ + A +PPG ++ + +D+TK+AVT+TW P
Sbjct: 7543 IPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPD 7602
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQ 886
DGG+P+ GY VER ++ WV NK P++ T V GL +Y FRV+A N AGPG+
Sbjct: 7603 DDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGK 7662
Query: 887 PSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDT 944
PS + ++ KDP+ PP V D +S+ L W +P G Y++EM T
Sbjct: 7663 PSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGT 7722
Query: 945 KEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV---RAMPPPAA 1001
EW + + + T + + GL+E Q+Y FR+RAVN+AG EP E V + PP+
Sbjct: 7723 DEWVRVAE-GVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSP 7781
Query: 1002 PKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
P++ + + A + GSP + I +K V KG +T+ + ++
Sbjct: 7782 PRWLEVINITKN---TADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7838
Query: 1062 INSTKRSDSGVYRILLQNEFGEARY---DIHVRVAD---FPRPPTNLRLFEEVPNTVTLT 1115
+ V+R+ +N G++ Y + V D P PP L + + V L
Sbjct: 7839 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLK 7898
Query: 1116 WNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSN-KYTVTGLLPGRKYYFRVVAR 1172
W P + G Y+I K++ W A + + + VT ++ G + F+V A
Sbjct: 7899 W--EPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAE 7956
Query: 1173 NEIGDSEP 1180
NE G P
Sbjct: 7957 NEAGVGHP 7964
Score = 285 bits (729), Expect = 2e-76
Identities = 315/1307 (24%), Positives = 527/1307 (40%), Gaps = 123/1307 (9%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
EF+ KPQ + EG+KA F + + P + WKR+ ++ K + K+ VL +
Sbjct: 6248 EFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKT-LESGDKYDVIADGKKRVLVV 6305
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTV-----------SLLVTEGQEKM-------DFKKM 169
+ T D Y + A A TV V E QE + + K
Sbjct: 6306 KDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKA 6365
Query: 170 LKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKV 229
R A K + +K+++ L ++ T+ RG K V
Sbjct: 6366 KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVK-SAANLIV 6424
Query: 230 EVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPL----RIQYSLGKYD 285
E E +RI++PL+D ET +V F C ++ NV + W K E + R+ Y + KY
Sbjct: 6425 EEEDLRIVEPLKDIETMEKKSVTFWC--KVNRLNVTLKWTKNGEEVPFDNRVSYRVDKY- 6481
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
K+ML I + D G Y ++ G + AEL +++ P +F+ ++ VTE A
Sbjct: 6482 ------KHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDA 6535
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
VF +LS+++ N W NG+E+K KY+ +DG H L IKD RL D E++ +
Sbjct: 6536 VFSCQLSREKANVKWYRNGREIKEGKKYKF--EKDGSIHRLIIKDCRLDDECEYACGVED 6593
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
+A+L ++ IP++ + +++ + EL V ++W ++ +++ G K+
Sbjct: 6594 RKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQ 6653
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
M EGK L I D + D GEY +A +D + A +K+ D+
Sbjct: 6654 MMSEGKIHRLQICDIKPRDQGEYRFIA-KDKEARAKLELAAAP------KIKTADQDLVV 6706
Query: 526 ATGSPAELCVVLND-EKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
G P + V + K E W K+ + ++ + + +++ G + K
Sbjct: 6707 DVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT-IDTTAEQTSFRILEAKKGDKGRYKIV 6765
Query: 585 FRAKGTESEA----SVFIADPPTIDPSVLEAL-----AAHAITVKVGHTAHIKVPFRGKP 635
+ K ++E V P + V E A + G + I +
Sbjct: 6766 LQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRD 6825
Query: 636 LPKVTWY--KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
+ + TW D E E +++G + L +S R +G ++ D+ +
Sbjct: 6826 IKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE---PVETDNPVEARSK 6882
Query: 694 HLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGE 753
+ D P PP V +++ V + W+ P+ +GG +T +++E R W
Sbjct: 6883 Y----DVPGPPLN-VTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMT 6937
Query: 754 VDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP-LETEEVFAGNPIEPPGFASQPQVTD 812
V + + + V EG+ Y FR+ A N GV P T V +PIE P +D
Sbjct: 6938 VRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSD 6997
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
T+ +V + W P +DGG+P+LGYI+ER ++G + W+ N + V GL + +Y
Sbjct: 6998 QTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKY 7057
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPP 932
+RV A NKAG PS + A D P + DL + + + P P
Sbjct: 7058 LYRVSAENKAGVSDPSEILGPLTADDAFVEPTM--DL---SAFKDGLEVIVPNPITILVP 7112
Query: 933 S-GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDK 991
S GY T W K+ +G +R K + A E + DK
Sbjct: 7113 STGY-----PRPTATWCFGDKVLETG---------DRVK-MKTLSAYAELVISPSERSDK 7157
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAG----------TALCIHAAFS------GSPPPD 1035
G+ + K +S + +++ R T +H + GSP
Sbjct: 7158 GIYTLKLENRVK-TISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTG 7216
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGE---ARYDIHVRV 1092
+ +K V K + +F + + ++++ +N+ G A D V +
Sbjct: 7217 YVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNM 7276
Query: 1093 ---ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERV 1149
A P PP N++ + N++ LTW+ + YI+ + + W E V
Sbjct: 7277 STPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPV 7336
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
K VTGL G+ Y +RV A N G S+P SR T ++IQ + + P D
Sbjct: 7337 AETKMEVTGLEEGKWYAYRVKALNRQGASKP--SRPT-----EEIQAVDTQEAPEIFLD- 7388
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
V L TV G + G P P +T K D+ + + + + T
Sbjct: 7389 ------VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST 7442
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
+ I D+G Y + N G+ + + V DK IT+
Sbjct: 7443 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITD 7489
Score = 273 bits (699), Expect = 6e-73
Identities = 160/493 (32%), Positives = 252/493 (51%), Gaps = 15/493 (3%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ +E + ++ + +KW P+ +GG P+T +IVE+R V +K W + + K T
Sbjct: 7779 PSPPRW-LEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV-DTTVKDTK 7836
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVT 819
+ + EG Y FR+ A N+ G SD E E+ V A + PG V DVTK V
Sbjct: 7837 CTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVD 7896
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAV 879
+ W P DGG P+ Y++E++++ WV K V ++E TE +F+V A
Sbjct: 7897 LKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAE 7956
Query: 880 NKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYIL 937
N+AG G PS P+ + +DP PP DLHV+D+ I++AW+ P + G P GY +
Sbjct: 7957 NEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHV 8016
Query: 938 EMRAEDTKEWSKCTKIPISGTCYTV-GGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
EM T++W + PI + V G++ ++Y R+RAVN GV EP E+ + V A
Sbjct: 8017 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 8076
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKN 1056
P P DL ++V G L I F P P V W KDG K + +T +
Sbjct: 8077 DPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKND 8133
Query: 1057 H--SQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
H + + + R+D+G+Y I L+N+ G A I+V+V P P +++ + ++ L
Sbjct: 8134 HISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKL 8193
Query: 1115 TWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVAR 1172
TW P + G HY++ +R+A T+ +TV L+P +Y+FRV A
Sbjct: 8194 TW--EPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 8251
Query: 1173 NEIGDSEPLDSRD 1185
N++G E ++ ++
Sbjct: 8252 NKVGGGEYIELKN 8264
Score = 255 bits (652), Expect = 2e-67
Identities = 168/569 (29%), Positives = 270/569 (47%), Gaps = 36/569 (6%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
I V+ G + +P +GKP P W K+G ++++ R + E L I R DSG
Sbjct: 23841 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK--RAMIATSETHTELVIKEADRGDSG 23898
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
L L+N G + + V+ P P+G +E+ ++ V + W+ P D+GG + +
Sbjct: 23899 TYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGY 23958
Query: 737 IVERRAVGKKSWIKIGEVDGKV--TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF 794
I+ERR V K +W I D +V T+ ++E Y FR+ A N G+S PL++EE
Sbjct: 23959 ILERREVPKAAWYTI---DSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 24015
Query: 795 AG----NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP 850
NP EPP ++ P+V DVTK +V+++W+ P DGG+ V GY +ER++ ++ WV
Sbjct: 24016 TPKTPLNPPEPP--SNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24073
Query: 851 VNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLH 910
NK I T TV GL+ D EY+FR+IA N G + S S VV KDP P +L
Sbjct: 24074 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24133
Query: 911 VSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ S S++L W +P G GY +E R W K K I +T+GGL+E
Sbjct: 24134 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24193
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRA-MPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
+Y FR+ A NE G+ P ++ + AP + +K + + G A +
Sbjct: 24194 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAP--GIRKEMKD-VTTKLGEAAQLSCQ 24250
Query: 1028 FSGSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEA 1084
G P PD+ W + G + ++ + + + H+ + + ++ D GVY + NE GE
Sbjct: 24251 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT-LTVMTEEQEDEGVYTCIATNEVGEV 24309
Query: 1085 RYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
+ + P+ L E+ V T H + + R TW+
Sbjct: 24310 ETSSKLLLQATPQFHPGYPLKEKYYGAVGSTL----------RLHVMYIGRPVPAMTWF- 24358
Query: 1145 AAERVFSNKYTVTGLLPGRKYYFRVVARN 1173
+++ N +T + ++Y +V +N
Sbjct: 24359 HGQKLLQNSENIT--IENTEHYTHLVMKN 24385
Score = 252 bits (643), Expect = 2e-66
Identities = 205/799 (25%), Positives = 359/799 (44%), Gaps = 50/799 (6%)
Query: 438 LECELTSKD-VTLRWKK---DG--QLLMHGTKYSMNHEG---KRAELIIEDAQLSDGG-- 486
LE SKD VTL+W+K DG ++L + +Y + + K + I+D Q + GG
Sbjct: 24132 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 24191
Query: 487 -----EYTVVAMQDGDPTEYYSTAIVTVEERLAT-----VKSGMSDVHAATGSPAEL-CV 535
E+ V A + + TA+ +++ +L + ++ M DV G A+L C
Sbjct: 24192 EATEYEFRVFAENETGLSRPRRTAM-SIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24250
Query: 536 VLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKG----TE 591
++ + W + GKE+ ++ G H L + E EG YT A E
Sbjct: 24251 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24310
Query: 592 SEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE 651
+ + + + P P + VG T + V + G+P+P +TW+ +
Sbjct: 24311 TSSKLLLQATPQFHPGYPLKEKYYGA---VGSTLRLHVMYIGRPVPAMTWFHGQKLLQNS 24367
Query: 652 ERVSMERGEDQALLTISNCVRED-SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEF 710
E +++E E L + N R+ +G ++L N G+ A L + + D+P P G +
Sbjct: 24368 ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVI 24427
Query: 711 LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGK 770
L + + WK P D+GG +T ++VE+ + + ++ VT + E
Sbjct: 24428 EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 24487
Query: 771 AYQFRILAVNSEGVSDPLETEEV-FAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDG 829
Y FR+ A N+ G+SDPLE V +P E PG +P +T VTK++ + W P DG
Sbjct: 24488 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDG 24547
Query: 830 GAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSV 889
GA + Y +E+R+K N W+ V + I+ T +V L+E EYEFRV N G + S
Sbjct: 24548 GAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSE 24607
Query: 890 PSSSVVAKD--PVKPPGLVQDL-HVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKE 946
S + K P++ P ++L +++ S+ +L + P + + + E +
Sbjct: 24608 ISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK-EIIAD 24666
Query: 947 WSKCTKIPISGTCY--TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKF 1004
K G + + + + +++RA N+ G G ++ K
Sbjct: 24667 GLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGG------SVSGTASLEVEVPAKI 24720
Query: 1005 DLSARLKSHMVVRA--GTALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQF 1060
L L+ V A G + I FSG P P + WQK D + G + +++ +
Sbjct: 24721 HLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSL 24780
Query: 1061 LI-NSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHS 1119
+ N +R D+G Y + +N FG + + + VAD P PP +++ + ++V LTW
Sbjct: 24781 VFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24840
Query: 1120 PDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
+YI+ ++ A+TA + + +YTV L Y FRV+A N+ G S+
Sbjct: 24841 ASDGGSKITNYIV-EKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSK 24899
Query: 1180 PLDSRDTWLINKDQIQDLS 1198
P + + + +D+ + ++
Sbjct: 24900 PSEPSEPTITKEDKTRAMN 24918
Score = 243 bits (621), Expect = 7e-64
Identities = 306/1277 (23%), Positives = 500/1277 (39%), Gaps = 142/1277 (11%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARV-QGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
EF + + T EG AV V + NAK + W + +G I +S K + + L
Sbjct: 5981 EFTKPLEDQTVEEGATAVLECEVSRENAK--VKWFK-NGTEILKSKKYEIVADGRVRKLV 6037
Query: 127 LEPLTSDDSDNYKCIASN-----------DHADAIYTVSLLVTEGQEKMDFK-------- 167
+ T +D Y C A + H + + ++ L +E F+
Sbjct: 6038 IHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENA 6097
Query: 168 --KMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEM 225
K K A KK ++ + +++K D + E G+L L+E
Sbjct: 6098 KVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEE- 6156
Query: 226 KKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYD 285
EA+ K L + E T+ C E+ P ++IW KG E + G+Y+
Sbjct: 6157 ------EAV-FTKNLANIEVSETDTIKLVC--EVSKPGAEVIWYKGDEEI---IETGRYE 6204
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
+ G K +LVI N ++ DAG Y+ + R ++ V + +F+ + + +++ E + A
Sbjct: 6205 ILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKA 6264
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
F +SK+ WK + K L+ DKY++ DG L +KDA L D G + G
Sbjct: 6265 EFVCSISKESFPVQWKRDDKTLESGDKYDVIA--DGKKRVLVVKDATLQDMGTYVVMVGA 6322
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
A LT+ ++ V LK+ RVKE+ CE+ ++ +W ++ + + +KY
Sbjct: 6323 ARAAAHLTVIE-KLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYI 6381
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ + L I DA L D Y V ++ + S A + VEE + + D+
Sbjct: 6382 ILQKDLVYTLRIRDAHLDDQANYNV-SLTNHRGENVKSAANLIVEEEDLRIVEPLKDIET 6440
Query: 526 ATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
+N V W K+G+E+ + H L G EG+Y
Sbjct: 6441 MEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIV 6500
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
A +S A + I + PT +E L +T ++ + V WY++G
Sbjct: 6501 TAGQDKSVAELLIIEAPT---EFVEHLEDQTVTEFDDAVFSCQL---SREKANVKWYRNG 6554
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
E+ E ++ E+ L I +C +D +++ A + ++ +PPQ
Sbjct: 6555 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQ 6614
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAV--GKKSWIKIGEVDGKVTNFST 763
+ LE G+ V + KD + Q++ V G K + +GK+
Sbjct: 6615 ---DILEAPGADVVFLAELNKD---KVEVQWLRNNMVVVQGDKHQMMS---EGKIHRLQI 6665
Query: 764 NKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWN 823
++ ++R +A + E + E+ A I+ A Q V DV K +
Sbjct: 6666 CDIKPRDQGEYRFIAKDKEARAKL----ELAAAPKIKT---ADQDLVVDVGKPLTMVV-- 6716
Query: 824 APTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAG 883
P Y K W N +P+ TK T+D E T FR++ K
Sbjct: 6717 --------PYDAY-----PKAEAEWFKEN-EPLS-TK-TIDTTAEQTS--FRILEAKKGD 6758
Query: 884 PGQPSV-------PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSG 934
G+ + + + + PG V++L V+++ + +SLAW EP G G
Sbjct: 6759 KGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIG 6818
Query: 935 YILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQ-KYFFRIRAVNEAGVGEPVELDKGV 993
Y++E R K W T S +TV GL + +Y FR+ A N G GEPVE D V
Sbjct: 6819 YVVERRDIKRKTWVLATDRAESCE-FTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPV 6877
Query: 994 RAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD----------VIWQKDGV 1043
A P L+ + V R G +L PP+ VI +D
Sbjct: 6878 EARSKYDVPGPPLNVTITD--VNRFGVSLTWE-------PPEYDGGAEITNYVIELRDKT 6928
Query: 1044 PTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDI---HVRVAD---FPR 1097
+ +T + +R+ QN G + V+VAD P
Sbjct: 6929 SIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPS 6988
Query: 1098 PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSN-KY 1154
PP NL ++ ++V L W P +++ G YII + + W ++ Y
Sbjct: 6989 PPVNLTSSDQTQSSVQLKWE--PPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTY 7046
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPR 1214
VTGL G KY +RV A N+ G S+P + L D + + L ++ P
Sbjct: 7047 KVTGLEKGNKYLYRVSAENKAGVSDPSEILGP-LTADDAFVEPTMDLSAFKDGLEVIVPN 7105
Query: 1215 FVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPT 1274
+T L P T G PRPT T GD + + + S LVI
Sbjct: 7106 PITILVPST--------------GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISP 7151
Query: 1275 CTLKDSGDYSVLVENEL 1291
D G Y++ +EN +
Sbjct: 7152 SERSDKGIYTLKLENRV 7168
Score = 208 bits (529), Expect = 3e-53
Identities = 167/633 (26%), Positives = 273/633 (43%), Gaps = 66/633 (10%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
D P PP R+E +++ V + W P D+GG P+T + VER W++ ++ K
Sbjct: 7576 DPPGPPT-RLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD 7634
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVTKEA 817
T + + K Y+FR+LA N G P + TE + +PI+PP +P V DV K +
Sbjct: 7635 TTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTS 7694
Query: 818 VTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVI 877
V + W P DGGA + Y++E K G++ WV V + + T+ + GL+E EY FRV
Sbjct: 7695 VRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVR 7753
Query: 878 AVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGY 935
AVNKAG +PS PS V+ ++ + PP + L V + + ++ L W P + G P + Y
Sbjct: 7754 AVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNY 7813
Query: 936 ILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRA 995
I+E R K W + + T TV L E Y FR+ A N G + E++ V A
Sbjct: 7814 IVEKRDVRRKGW-QTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLA 7872
Query: 996 M-------PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD---------VIWQ 1039
PP A D++ R H PP + VI +
Sbjct: 7873 KDTFTTPGPPYALAVVDVTKR---------------HVDLKWEPPKNDGGRPIQRYVIEK 7917
Query: 1040 KDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADF---- 1095
K+ + T+ + + F + +++ +NE G +
Sbjct: 7918 KERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPT 7977
Query: 1096 --PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFS 1151
P PP +L + + + + W P + G Y + T W R
Sbjct: 7978 SPPSPPLDLHVTDAGRKHIAIAWK--PPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 8035
Query: 1152 N-KYTVT-GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
+ K+ V G++P ++Y RV A N IG SEP + + ++ KD + L+ ++
Sbjct: 8036 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISEN-VVAKDPDCKPTIDLETHDI--- 8091
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
V+ G+ ++ F P PTV+ +K + A+ + +
Sbjct: 8092 -------------IVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8138
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L +P D+G Y++ +EN+LG +S + V
Sbjct: 8139 LEVPKSVRADAGIYTITLENKLGSATASINVKV 8171
Score = 208 bits (529), Expect = 3e-53
Identities = 143/432 (33%), Positives = 213/432 (49%), Gaps = 26/432 (6%)
Query: 762 STNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTIT 821
+ N+ + GK + + NS G V ++ PG +V +VTK +VT+T
Sbjct: 15615 NVNRFDSGK---YILTVENSSGSKSAFVNVRV-----LDTPGPPQDLKVKEVTKTSVTLT 15666
Query: 822 WNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNK 881
W+ P DGG+ + YIVE+R+ + V + T VD L E Y FRV+A N+
Sbjct: 15667 WDPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENE 15725
Query: 882 AGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEM 939
G G P+ + SV A + PPG + + D + +S+SL+W +P G GYI+EM
Sbjct: 15726 YGIGLPAETAESVKASERPLPPGKIT---LMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15782
Query: 940 RAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP 999
+ + + +W+ C + ++ T+ GLI+ ++Y FR+ A NE G+ +P +L V A
Sbjct: 15783 QTKGSDKWATCATVKVTEA--TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV 15840
Query: 1000 AAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKG--RETITKSKNH 1057
P F L L + V AG L + F G P P V W KD VP K R ++N+
Sbjct: 15841 IPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN 15897
Query: 1058 SQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTW 1116
S I R D G Y + L N GEA ++V V D P PPT +++ E +++TL+W
Sbjct: 15898 SLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSW 15957
Query: 1117 NHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNE 1174
P + G + +YI+ KRD ST TW + V L G +Y FR+ A N
Sbjct: 15958 G--PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENR 16015
Query: 1175 IGDSEPLDSRDT 1186
G S L+S T
Sbjct: 16016 YGKSTYLNSEPT 16027
Score = 204 bits (518), Expect = 6e-52
Identities = 122/391 (31%), Positives = 190/391 (48%), Gaps = 6/391 (1%)
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N I P + + D+TK++V +TW P DGG+P+ GY+VE+R+ W V D +
Sbjct: 7178 NVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDFV 7236
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ TV L++ EY F+V A NK GPG+P+ V P P +++ D +
Sbjct: 7237 TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTA 7296
Query: 917 SSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+SI L W P G GYI+E + +W C + P++ T V GL E + Y +R
Sbjct: 7297 NSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGE-PVAETKMEVTGLEEGKWYAYR 7355
Query: 975 IRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPP 1034
++A+N G +P + ++A+ AP+ L +L + + V+AGT + + A +G P P
Sbjct: 7356 VKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP 7415
Query: 1035 DVIWQKDGVPTKG--RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV 1092
+ W K + K R TI S I +KRSD+G Y I N G A + V V
Sbjct: 7416 KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7475
Query: 1093 ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSN 1152
D P PP + + + LTWN D +Y++ +R + W+ + V
Sbjct: 7476 LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDT 7535
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ T L+P ++Y FRV A N G EP+ +
Sbjct: 7536 NFKATKLIPNKEYIFRVAAENMYGVGEPVQA 7566
Score = 201 bits (512), Expect = 3e-51
Identities = 144/532 (27%), Positives = 249/532 (46%), Gaps = 31/532 (5%)
Query: 168 KMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKK 227
K K P K + V+ K +L + D + +T G L E K
Sbjct: 2780 KWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGE------YTAVVGQL----ECKA 2829
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K+ VE + I K +++ E T F+C E+ NV +W+K + + K+ +
Sbjct: 2830 KLFVETLHITKTMKNIEVPETKTASFEC--EVSHFNVPSMWLKNGVEIEMSE---KFKIV 2884
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G + L+I N + D+ Y+ G+ ++SA LTV P+ +K + E+ T F
Sbjct: 2885 VQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVT--PIMITSMLKDINAEEKDTITF 2942
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E+ ++ + ++ W NG E+K DK ++ + LTH+L I++ D+ +++ AG
Sbjct: 2943 EVTVNYEGISYKWLKNGVEIKSTDKCQMRTKK--LTHSLNIRNVHFGDAADYTFVAGKAT 3000
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A L ++ I+F ++K+++V E+ RA ECE++ D+T++W KD Q L + +
Sbjct: 3001 STATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQ 3060
Query: 468 HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT 527
E L+I ++SD G+YTVVA + STA + VE R ++S +V
Sbjct: 3061 KEKYVHRLLIPSTRMSDAGKYTVVAGGN------VSTAKLFVEGRDVRIRSIKKEVQVIE 3114
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEIT--DLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A + +N++ V+ W KDG EI + V + +H++ G+YTF
Sbjct: 3115 KQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTF 3174
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
A S ++++ P P VL+ L +TV+ G A G+P PK++WYK+
Sbjct: 3175 VAGRNRSSVTLYVNAPE--PPQVLQEL--QPVTVQSGKPARFCAVISGRPQPKISWYKEE 3230
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
++ + + L + ED+ + + KND+G AT + LSV
Sbjct: 3231 QLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 201 bits (512), Expect = 3e-51
Identities = 137/438 (31%), Positives = 208/438 (47%), Gaps = 44/438 (10%)
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
PG + +D+TK + +TW P DGG P+L Y++ERR+ G ++PV +
Sbjct: 8175 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENK-LSW 8233
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
TV L+ + EY FRV AVNK G G+ + V+A+DP +PP D+ V + + ++++
Sbjct: 8234 TVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTI 8293
Query: 922 AWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVN 979
W+ P G GYI+E A+ + W +C + + YT GL E ++Y FR+RA N
Sbjct: 8294 TWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAEN 8353
Query: 980 EAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQ 1039
AG+ EP +A+ P APK L++ + V+ G + + A+ SGSP P + W
Sbjct: 8354 AAGISEPSRATPPTKAVDPIDAPK----VILRTSLEVKRGDEIALDASISGSPYPTITWI 8409
Query: 1040 KDG------------------------------VPTKGRETITKS-KNHSQFLINSTKRS 1068
KD +P R +I S K SQ + + R
Sbjct: 8410 KDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP 8469
Query: 1069 DSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNT-VTLTWNHSPDVQEDGE 1127
D G+Y I ++N+ G A+ V V D P PP N +FE++ T V W D
Sbjct: 8470 DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEI 8528
Query: 1128 AHYIIMKRDAS--TATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+Y + K+D + + W + KY+VT L+ G++Y FRV A N G P S+
Sbjct: 8529 INYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKP 8588
Query: 1186 TWLINKDQIQDLSAKLKP 1203
L+ KD A KP
Sbjct: 8589 --LVAKDPFGPPDAPDKP 8604
Score = 201 bits (510), Expect = 5e-51
Identities = 167/595 (28%), Positives = 274/595 (46%), Gaps = 38/595 (6%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+ P +D L++ I V+ G +A I +PF+G+P P++TW ++ E T+ +V +E+G
Sbjct: 17715 EAPELD---LDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD--KVQIEKG 17769
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
+ L+I NC R D+G +LKL+N GS +A + + VLD P PPQ + E+
Sbjct: 17770 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQN-LAVKEVRKDSAF 17828
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAV 779
+ W+ P +GG V +++++R +K++ + K T+F + EG Y FR++A
Sbjct: 17829 LVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLTEGAIYYFRVMAE 17887
Query: 780 NSEGVSDPLET-EEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
N GV P+ET + V A P PPG + +TDV++ + ++ W P DGG+ VLGY+V
Sbjct: 17888 NEFGVGVPVETVDAVKAAEPPSPPGKVT---LTDVSQTSASLMWEKPEHDGGSRVLGYVV 17944
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
E + KG+ W V + + V GL EY+FRV A N+ G P V V+AKD
Sbjct: 17945 EMQPKGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 18002
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGT 958
P L + + S + L P G P E K+ T++ + T
Sbjct: 18003 LTIQPSLKLPFN-TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQ---TTRVNVEET 18058
Query: 959 C-YTVGGLIERQKYFF---RIRAVNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSH 1013
TV + E K F + A N AG E + + + PP +FD + +
Sbjct: 18059 ATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFD---EVSAD 18115
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
VV + A G + I +K T ++ + + I K +
Sbjct: 18116 FVVISWEP---PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQF 18172
Query: 1074 RILLQNEFGE-ARYDIHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE- 1127
RI +N +G+ A D + + P PP + + + + W H P V + G
Sbjct: 18173 RIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQW-HEP-VNDGGTK 18230
Query: 1128 -AHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
Y + +++ ++ W + + K+ TGL G +Y F+V A N +G +P
Sbjct: 18231 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKP 18285
Score = 200 bits (509), Expect = 7e-51
Identities = 157/596 (26%), Positives = 262/596 (43%), Gaps = 26/596 (4%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+PP + +L+A A +KVG T + +G P PKVTW K+ + + R+ +
Sbjct: 10909 EPPEL---ILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPV 10965
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
+ L I N ED G+ L ++N GS T ++ + VLD+P PP+ +E E+ +
Sbjct: 10966 GSK--LEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRD-LEVSEIRKDSCY 11022
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAV 779
+ WK P D+GG +T ++VERR V W + K ++F+ + + EG Y FR+ A
Sbjct: 11023 LTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH-LNEGNQYLFRVAAE 11081
Query: 780 NSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
N G +ET + + A +P+ PPG DV K V++ WN P +DGG+P+ GY+V
Sbjct: 11082 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11141
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
E +++G+ W+ + +C V GL + Y FRV A N G G P + + ++
Sbjct: 11142 EYQEEGTQDWIKFK--TVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDT-TIPIECQE 11198
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDP-PSGYILEMRAEDTKEWSKCTKIPI 955
+ PP + D+ + + R PA G P P+ +E + +
Sbjct: 11199 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11258
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
+ T+ + R ++I N AG + V + V +P P ++ HM
Sbjct: 11259 FSSVLTIKNCLRRDTGEYQITVSNAAG-SKTVAVHLTVLDVPGPPTGPINILDVTPEHMT 11317
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
+ GSP + I +K ++ + ++ I ++ V+R+
Sbjct: 11318 ISWQPP----KDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRV 11373
Query: 1076 LLQNEFG-----EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHY 1130
+N+ G ++ + P PP + + N T++W P
Sbjct: 11374 RAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWT-LPKSDGGSPITG 11432
Query: 1131 IIMKRDASTATWYTAAERVFSN-KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
M+R T W + ++ K+ VTGL G Y FRV A N G S+P S D
Sbjct: 11433 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11488
Score = 196 bits (497), Expect = 2e-49
Identities = 174/653 (26%), Positives = 280/653 (42%), Gaps = 42/653 (6%)
Query: 567 VHKLIFPSMGPEHEGKYTFRAKGTESEASV---------FIADPPTIDPSVLEALAAHAI 617
V +L + G E KY +R E++A V AD ++P++ + +
Sbjct: 7041 VPELTYKVTGLEKGNKYLYRVSA-ENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGL 7099
Query: 618 TVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGL 677
V V + I VP G P P TW + +RV M+ A L IS R D G+
Sbjct: 7100 EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGI 7159
Query: 678 ILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFI 737
LKL+N + + + ++V+ RP P+ ++F +++ VH+ W+ P D+GG P+T ++
Sbjct: 7160 YTLKLENRVKTISGEIDVNVIARPSAPK-ELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 7218
Query: 738 VERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAG 796
VE+R V +K+W K+ + + F+ + +GK Y F++ A N G +P +E V
Sbjct: 7219 VEKREVSRKTWTKVMDFVTDL-EFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMS 7277
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
P P + D T ++ +TW+ P DGG+ + GYIVER +GS+ WV +P+
Sbjct: 7278 TPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG-EPV 7336
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
TK V GL E Y +RV A+N+ G +PS P+ + A D + P + D+ +
Sbjct: 7337 AETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLT 7396
Query: 917 SSISLAWREPAE-GDPPSGYILEMRAEDTKEWSK---CTKIPISGTCYTVGGLIERQKYF 972
PA P I +A+ + K +P T T+
Sbjct: 7397 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST-VTIVDSKRSDTGT 7455
Query: 973 FRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSP 1032
+ I AVN G V + PPAA FD++ ++ GS
Sbjct: 7456 YIIEAVNVCGRATAVVEVNVLDKPGPPAA--FDITDVTNESCLLTWNPP----RDDGGSK 7509
Query: 1033 PPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---------- 1082
+ + ++ ++ ++ + + F + ++R+ +N +G
Sbjct: 7510 ITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPI 7569
Query: 1083 EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATW 1142
A+Y D P PPT L + + VTLTW D Y + + D T W
Sbjct: 7570 TAKYQF-----DPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKW 7624
Query: 1143 YTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQI 1194
+ V Y V GL +KY FRV+A N G +P S + LI KD I
Sbjct: 7625 VRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI-KDPI 7676
Score = 196 bits (497), Expect = 2e-49
Identities = 143/520 (27%), Positives = 238/520 (45%), Gaps = 28/520 (5%)
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
L+ P+PP E L+++ S V + W PKD+GG VT + +ER+ W++ +
Sbjct: 24021 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 24080
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKE 816
T ++ + YQFRI+A N G+S+ E V +P + P + ++ ++K+
Sbjct: 24081 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 24140
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
+VT+ W P DGG +LGY VE R+ G + W NK+ I+ + T+ GLLE TEYEFRV
Sbjct: 24141 SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRV 24200
Query: 877 IAVNKAGPGQPSVPSSSVVAK-DPVKPPGLVQDLH-----VSDSSNSSISLAWREPAEGD 930
A N+ G +P + S+ K + PG+ +++ + +++ S + R
Sbjct: 24201 FAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGR------ 24254
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKY--FFRIRAVNEAGVGEPVE 988
P I R S+ K+ G +T+ + E Q+ + A NE G E
Sbjct: 24255 -PLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG-----E 24308
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGR 1048
++ + + A P+F LK G+ L +H + G P P + W +
Sbjct: 24309 VETSSKLLLQ-ATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNS 24367
Query: 1049 ETIT-KSKNHSQFLI--NSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLF 1105
E IT ++ H L+ N +++ +G Y++ L N FG + V + D P PT +
Sbjct: 24368 ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVI 24427
Query: 1106 EEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDAST-ATWYTAAERVFSNKYTVTGLLPGR 1163
E + N+ ++W D +Y++ K +A A W + + + L
Sbjct: 24428 EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 24487
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203
YYFRV A+N G S+PL+ +I K + A KP
Sbjct: 24488 GYYFRVSAQNTFGISDPLEVSSVVII-KSPFEKPGAPGKP 24526
Score = 195 bits (496), Expect = 2e-49
Identities = 163/617 (26%), Positives = 271/617 (43%), Gaps = 43/617 (6%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ E ++ + + W P +GG + +IVERR + WIK +
Sbjct: 15350 PDPPKNP-EVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR 15408
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVT 819
+ + + EG Y+FRI+A N+ G+S P T + A + + PG P+V D ++ +++
Sbjct: 15409 YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSIS 15468
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLEDTEYEFRVIA 878
I WN P DGG+ + GY+VE + W V ++ T T+ GL E+ EY+ R+ A
Sbjct: 15469 IAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYA 15528
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPG--LVQDLHVSDSSNSSISLAWREPAEGDPPSGYI 936
+N G G+P++ + A+D + PP L DL + + +L P +G P
Sbjct: 15529 MNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPE-- 15586
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
++ + + K + S + G + R I V + + ++ VR +
Sbjct: 15587 VKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVN--VRVL 15644
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKS 1054
P P+ LK V + L GS + I +K K T+ +
Sbjct: 15645 DTPGPPQ-----DLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATN 15699
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNT 1111
+ + + ++ + S +R+L +NE+G A V+ ++ P PP + L + N+
Sbjct: 15700 CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS 15759
Query: 1112 VTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFR 1168
V+L+W + DG + YI+ + + W T A V + T+TGL+ G +Y FR
Sbjct: 15760 VSLSWEKP---EHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFR 15815
Query: 1169 VVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQ 1228
V A+NE G S+P + LS P KD P F TVL G+
Sbjct: 15816 VSAQNEKGISDP--------------RQLSV---PVIAKDLVIPPAFKLLFNTFTVLAGE 15858
Query: 1229 DCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVE 1288
D + F+G P P VT +K +V + ++ ST L I +D G Y V +
Sbjct: 15859 DLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLT 15918
Query: 1289 NELGKDRSSCTLTVYDK 1305
N G+ + + V DK
Sbjct: 15919 NSAGEAIETLNVIVLDK 15935
Score = 193 bits (491), Expect = 8e-49
Identities = 124/393 (31%), Positives = 189/393 (48%), Gaps = 9/393 (2%)
Query: 799 IEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG 858
++ PG +V+++ K++ +TW P DGG+ + Y+VERR S W P++ +
Sbjct: 11002 LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKK 11061
Query: 859 TKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSS 918
+ L E +Y FRV A N+ G G + A DP+ PPG +DLH D +
Sbjct: 11062 SHFAKH-LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTE 11120
Query: 919 ISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIR 976
+SL W +P G P +GY++E + E T++W K + + V GL + + Y FR++
Sbjct: 11121 VSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTV--TNLECVVTGLQQGKTYRFRVK 11178
Query: 977 AVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
A N G+G P + + P +L +L +VV+AGT + A G P P
Sbjct: 11179 AENIVGLGLP-DTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTA 11237
Query: 1037 IWQKDGVPTKGRETIT-KSKNHSQFL-INSTKRSDSGVYRILLQNEFGEARYDIHVRVAD 1094
W DG K E T ++ N S L I + R D+G Y+I + N G +H+ V D
Sbjct: 11238 KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD 11297
Query: 1095 FPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNK 1153
P PPT + + + P +T++W D +YI+ K+D TW + K
Sbjct: 11298 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 11357
Query: 1154 YTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDT 1186
+ L G +Y FRV A N+IG PLDS T
Sbjct: 11358 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPT 11390
Score = 193 bits (491), Expect = 8e-49
Identities = 194/806 (24%), Positives = 335/806 (41%), Gaps = 105/806 (13%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
W KDG + G+++ Q + L S+ + G YT A+ + S TI
Sbjct: 13024 WKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSA------TIK 13077
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKD----GMEVT-----EEERVSM 656
VL+ K G A +K+ ++W G E+T + E
Sbjct: 13078 LKVLD---------KPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRP 13128
Query: 657 ERGEDQALLTISNC-----VREDSGLILLKLKNDHGSATATL-HLSVLDRPKPPQGRVE- 709
+ A + I++C + + +N +G ++ P P GR +
Sbjct: 13129 NWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 13188
Query: 710 --FLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVE 767
++ + + WK P D+GG P+T +++E+R +W K+ ++
Sbjct: 13189 PVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQ 13248
Query: 768 EGKAYQFRILAVNSEGVSDPLETEEV-FAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
EG Y+FR+ A+N G P + + +A +P PPG + P+V D T+ +V+++W P
Sbjct: 13249 EGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13308
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVN-KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPG 885
DGG+P++GY+VE ++ S+ WV N +Q T+ V GL+EDT+Y+FRV AVNK G
Sbjct: 13309 YDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYS 13368
Query: 886 QPSVPSSSVVAKDPVKPPG--LVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAED 943
PS KD + PP L DL + + +++ P +G PP
Sbjct: 13369 DPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKIT------- 13421
Query: 944 TKEWSKCTKIPISGTCYTVGGLIERQKY--FFRIRAVNEAGVGEPV----------ELDK 991
WSK P +G I+ + F R VN+ G+ + E
Sbjct: 13422 ---WSK----PNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTI 13474
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI 1051
V+ + P P ++ +K A GSP + + QK K T+
Sbjct: 13475 VVKVLDTPGPP---VNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 13531
Query: 1052 TKSKNHSQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRLFE 1106
T + + F + + + S +R+ +NE+G E R V+ + P P +L++
Sbjct: 13532 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTPGPVVDLKVRS 13589
Query: 1107 EVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTAT--WYTAAERVFSNKYTVTGLLPGRK 1164
++ ++ W DG + I D T W + + S +Y+ L G++
Sbjct: 13590 VSKSSCSIGWKKP---HSDGGSRIIGYVVDFLTEENKWQRVMKSL-SLQYSAKDLTEGKE 13645
Query: 1165 YYFRVVARNEIGDSEPLDSRDTWLINKDQI--QDLSAKLKP---YEKKDWRHAPRFVTPL 1219
Y FRV A NE G+ P + ++ +D + DL K P Y K+ + R P+
Sbjct: 13646 YTFRVSAENENGEGTP---SEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF-RLKIPI 13701
Query: 1220 KPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKD 1279
K G P P+V+ KG+ + +++ S++ TL++ C D
Sbjct: 13702 K-----------------GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSD 13744
Query: 1280 SGDYSVLVENELGKDRSSCTLTVYDK 1305
+G Y++ ++N G + ++ V K
Sbjct: 13745 AGKYTITLKNVAGTKEGTISIKVVGK 13770
Score = 193 bits (490), Expect = 1e-48
Identities = 138/458 (30%), Positives = 214/458 (46%), Gaps = 43/458 (9%)
Query: 749 IKIGEVDGKV------------TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
+K G+VDG++ T+ + V + ++ + NS G T V
Sbjct: 16669 VKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRV--- 16725
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
++ P +VT++TK++V+ITW P DGG+ + YIVE+R+ + V +
Sbjct: 16726 --LDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTN-C 16782
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+D L E Y FRV A N+ G G P+ + + + +PPG + V D +
Sbjct: 16783 HKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKIT---VDDVTR 16839
Query: 917 SSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+S+SL+W +P G YI+EM+A+ +++WS+C ++ T L + ++Y FR
Sbjct: 16840 NSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVIT--NLTQGEEYLFR 16897
Query: 975 IRAVNEAGVGEPVELDKGVRA----MPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSG 1030
+ AVNE G +P L + A + P P F S V+ G L I SG
Sbjct: 16898 VVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAF-------SSYSVQVGQDLKIEVPISG 16950
Query: 1031 SPPPDVIWQKDGVPTK--GRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDI 1088
P P + W KDG+P K R +T S + + I T + D G Y I + N G+ I
Sbjct: 16951 RPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASI 17010
Query: 1089 HVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDG--EAHYIIMKRDASTATWYTA 1145
+ D P PP F++V ++TL+WN P + G +YI+ KRD +T W
Sbjct: 17011 EIVTLDKPDPPKGPVKFDDVSAESITLSWN--PPLYTGGCQITNYIVQKRDTTTTVWDVV 17068
Query: 1146 AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ V VT L G +Y FR+ A N G S L+S
Sbjct: 17069 SATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALES 17106
Score = 191 bits (486), Expect = 3e-48
Identities = 152/474 (32%), Positives = 218/474 (45%), Gaps = 34/474 (7%)
Query: 730 GRPVTQF-IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVS--- 785
G P+ F IV R K +W K+G +D V + V+ F ++ ++ S
Sbjct: 12316 GCPIRLFAIVRGRPAPKVTWRKVG-IDNVVRKGQVDLVD---TMAFLVIPNSTRDDSGKY 12371
Query: 786 -----DPLETEEVFAG-NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE 839
+P + VF ++ PG S +V+DVTK + ++W P DGG+ V YIVE
Sbjct: 12372 SLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVE 12431
Query: 840 RRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDP 899
+R+ W V + ++ T V L+ EY FRV AVN+ GPG P+ V+A DP
Sbjct: 12432 KREADRKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12490
Query: 900 VKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAED--TKEWSKCTKIPI 955
+ P + L V++ + +S +LAW P G GYI R E+ W++ + +
Sbjct: 12491 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYS--VV 12548
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
V GL E +KY FR+ A N GV P E + A PK + +
Sbjct: 12549 KDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI----LMPEQIT 12604
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
++AG L I A G P P W+K D V T + K+ + S +I R DSG Y
Sbjct: 12605 IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYY 12664
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEA---H 1129
+ +N G I V V D P PP ++ + +L+W H P EDG + +
Sbjct: 12665 SLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSW-HIP--LEDGGSNITN 12721
Query: 1130 YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
YI+ K D S W TA V V L+PG++Y FRV A N G SEPL S
Sbjct: 12722 YIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTS 12775
Score = 191 bits (485), Expect = 4e-48
Identities = 165/599 (27%), Positives = 252/599 (42%), Gaps = 54/599 (9%)
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L+A I V G I GKP P VTW + E T + ++E + + I
Sbjct: 10221 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMN--ERTLPQEATIETTAISSSMVIK 10278
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
NC R G+ L KN+ G T+ + VLD P P L+ + W +P+D+
Sbjct: 10279 NCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDD 10338
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG P+T +++E+R +++W + + N + + +GKAY FRI A NS G+ +
Sbjct: 10339 GGSPITNYVIEKRESDRRAWTPVTYTVTR-QNATVQGLIQGKAYFFRIAAENSIGMGPFV 10397
Query: 789 ETEEVFA-GNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNL 847
ET E PI P +V +VTK VT+TWN P DGG+ ++ Y++E R G+
Sbjct: 10398 ETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 10457
Query: 848 WVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
+ V D + K TV GL E YE+RV AVN G G+PS + + KD + PP L
Sbjct: 10458 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 10517
Query: 908 DLH--VSDSSNSSISLAWREPAEGDPPSGYILEMR--AEDTKEWSKCTKIPI-------- 955
D ++ + +L R + P + + ED + K T +
Sbjct: 10518 DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAK 10577
Query: 956 ---SGT-CYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLK 1011
SG C V +K F ++ V+ G PP FD K
Sbjct: 10578 RSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--------------PPVGPVSFD--EVTK 10621
Query: 1012 SHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSG 1071
+MV+ L GS + I +K V +T + + ++
Sbjct: 10622 DYMVISWKPPL----DDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY 10677
Query: 1072 VYRILLQNEFG--------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQ 1123
++RI +N +G + RV D P P + E ++ +TWN D
Sbjct: 10678 IFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPI---VTEVTKDSALVTWNKPHDGG 10734
Query: 1124 EDGEAHYIIMKRDASTATWYTAAERVFS--NKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
+ +YI+ KR+ + W + K+ V LL G +Y FRV A NEIG +P
Sbjct: 10735 KP-ITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDP 10792
Score = 191 bits (484), Expect = 5e-48
Identities = 126/394 (31%), Positives = 187/394 (47%), Gaps = 11/394 (2%)
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N ++ PG +VT+VTKE TI+W P +GG+ + +IVE RK W V D
Sbjct: 11692 NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVT 11751
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ + LL + EY FRV A NK G G + ++A +P+ PG ++LH++D
Sbjct: 11752 K--RLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGK 11809
Query: 917 SSISLAWREP--AEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+ + L WR P G P Y +E R + + +W + K I T Y V +E Q Y FR
Sbjct: 11810 TFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFR 11869
Query: 975 IRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPP 1034
++ NE G + V+ ++ V P DL +L + V+AG + + A G P P
Sbjct: 11870 VQTKNEGGESDWVKTEE-VVVKEDLQKPVLDL--KLSGVLTVKAGDTIRLEAGVRGKPFP 11926
Query: 1035 DVIWQKDGVPT----KGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHV 1090
+V W KD T R I + S+F + KRSD G Y + N G V
Sbjct: 11927 EVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATV 11986
Query: 1091 RVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF 1150
V D P P NL++ + + T+ W+ D +YI+ K + W T + V
Sbjct: 11987 NVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVL 12046
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ TVT L+ G +Y FRV A N+IG P +S+
Sbjct: 12047 TPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESK 12080
Score = 189 bits (481), Expect = 1e-47
Identities = 158/580 (27%), Positives = 258/580 (44%), Gaps = 42/580 (7%)
Query: 619 VKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLI 678
V+ G + + + ++G+P P W K ++ R + + + LT+ NC R D+G
Sbjct: 22064 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL--RADIHTTDSFSTLTVENCNRNDAGKY 22121
Query: 679 LLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIV 738
L ++N+ GS + T + VLD P PP G + F +++ + W AP +GG + ++V
Sbjct: 22122 TLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGARIHHYVV 22180
Query: 739 ERRAVGKKSWIKIGEVDGKVTN--FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
E+R ++SW I E K T F N + EG Y FR+ AVN GV +P E E
Sbjct: 22181 EKREASRRSWQVISE---KCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVA 22237
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
E P + V D +K + + W P DGG+ + GY++E R+KGS+ WV
Sbjct: 22238 T--EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH--T 22293
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPP-----GLVQDLHV 911
+ TV+ L+E TEYEFRV A N AG +P SSV+ K+P P G+ L +
Sbjct: 22294 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQL-I 22352
Query: 912 SDSSNSSISLAWREPAEGDPP---SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ + S ++ P G P + + EMR ++T S T T TV +
Sbjct: 22353 TCKAGSPFTI--DVPISGRPAPKVTWKLEEMRLKETDRVSITT--TKDRTTLTVKDSMRG 22408
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAF 1028
+ + N AGV + + V P P ++S+ V+ G
Sbjct: 22409 DSGRYFLTLENTAGV-KTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEP----KDG 22463
Query: 1029 SGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR-YD 1087
G+ + I +K T + + S +Q + + +R+ +N FG ++ +
Sbjct: 22464 GGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE 22523
Query: 1088 IHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTA 1140
+A+ P PT ++ N +++ W + DG + Y + K++ +T
Sbjct: 22524 SAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWE---EPYHDGGSKIIGYWVEKKERNTI 22580
Query: 1141 TWYTAAE-RVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
W + Y VTGL+ G +Y FR A N G S+
Sbjct: 22581 LWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSK 22620
Score = 189 bits (480), Expect = 2e-47
Identities = 192/770 (24%), Positives = 305/770 (39%), Gaps = 73/770 (9%)
Query: 570 LIFPSMGPEHEGKYTFRAKGTESEAS------VFIADPPTIDPSVLEALAAHAITVKVGH 623
L+ P G YT A AS V P + P E+++A +T+
Sbjct: 9876 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSW-- 9933
Query: 624 TAHIKVPFRGKPLPKVTWYK-DGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKL 682
P + K+T Y + E + V + + TI + + +
Sbjct: 9934 -----FPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMA 9988
Query: 683 KNDHGSA--------TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
+N +G TA SV P P ++ + + + W+ P+ +GG PVT
Sbjct: 9989 QNKYGIGEPLDSEPETARNLFSVPGAPDKPT----VSSVTRNSMTVNWEEPEYDGGSPVT 10044
Query: 735 QFIVERRAVGKKSWIKIGEVDGKV----TNFSTNKVEEGKAYQFRILAVNSEGVSDP-LE 789
+ +E + K W ++ K ++ + EG YQFR+ A+N+ GV L
Sbjct: 10045 GYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLP 10104
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
++ A +PI PPG P+VTD TK + + W+ P +DGG+ V GYIVE +++G W
Sbjct: 10105 SDPATARDPIAPPG-PPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWE 10163
Query: 850 PVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDL 909
++GTK V GL E Y+FRV AVN AG G+P + + KD + P L D
Sbjct: 10164 KGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDA 10223
Query: 910 HVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIE 967
V D R A G PP M + + IS + +
Sbjct: 10224 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSM-VIKNCQR 10282
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
+ + + A NEAG + + V +P P F +H + L +
Sbjct: 10283 SHQGVYSLLAKNEAGERKKTII-VDVLDVPGPVGTPF------LAHNLTNESCKLTWFSP 10335
Query: 1028 FS--GSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG--- 1082
GSP + + +K + +T + + + + +RI +N G
Sbjct: 10336 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10395
Query: 1083 --EARYDIHVRVA-DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDA 1137
E + +R P P +L + E NTVTLTWN P + G +Y++ R
Sbjct: 10396 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWN--PPKYDGGSEIINYVLESRLI 10453
Query: 1138 STATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQD 1196
T ++ + + S KYTV GL G Y +RV A N +G +P
Sbjct: 10454 GTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP---------------- 10497
Query: 1197 LSAKLKPYEKKDWRHAPRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITA 1255
S KP KD P + +R G+ +T + G P+P V+ +K + ++
Sbjct: 10498 -SFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10556
Query: 1256 NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+ + +T L DSG Y V+VEN G + C + V D+
Sbjct: 10557 DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 10606
Score = 188 bits (477), Expect = 3e-47
Identities = 110/321 (34%), Positives = 176/321 (54%), Gaps = 12/321 (3%)
Query: 590 TESEASVFIADP---PTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
+E +V DP PTID L H I V G I VPFR P+P V+W+KDG
Sbjct: 8067 SEISENVVAKDPDCKPTID------LETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGK 8120
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
EV +R++M+ A L + VR D+G+ + L+N GSATA++++ V+ P P +
Sbjct: 8121 EVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKD 8180
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
++ +++ S + W+ P+ +GG P+ +++ERR G++++I + + K++ + +
Sbjct: 8181 -IKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLI 8239
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
G+ Y FR+ AVN G + +E + V A +P +PP +V + T EA+TITW P
Sbjct: 8240 PNGE-YFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPP 8298
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPG 885
DGG+ ++GYI+E+ KG W N+ + T GL E EY+FRV A N AG
Sbjct: 8299 LYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGIS 8358
Query: 886 QPSVPSSSVVAKDPVKPPGLV 906
+PS + A DP+ P ++
Sbjct: 8359 EPSRATPPTKAVDPIDAPKVI 8379
Score = 187 bits (475), Expect = 6e-47
Identities = 164/601 (27%), Positives = 274/601 (45%), Gaps = 52/601 (8%)
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
PP I+ L+A +T++ T + VP +G+P P+V W +D E ++ S+E
Sbjct: 15552 PPEIE---LDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGE--SLDKASIESTS 15606
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHM 720
LL + N R DSG +L ++N GS +A +++ VLD P PPQ ++ E++ + V +
Sbjct: 15607 SYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQD-LKVKEVTKTSVTL 15665
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W P +GG + +IVE+R +K++ + K T++ ++++EG +Y FR+LA N
Sbjct: 15666 TWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHK-TSWKVDQLQEGCSYYFRVLAEN 15724
Query: 781 SEGVSDPLET-EEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE 839
G+ P ET E V A PPG + + DVT+ +V+++W P DGG+ +LGYIVE
Sbjct: 15725 EYGIGLPAETAESVKASERPLPPG---KITLMDVTRNSVSLSWEKPEHDGGSRILGYIVE 15781
Query: 840 RRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDP 899
+ KGS+ W ++ T+ T+ GL++ EY FRV A N+ G P S V+AKD
Sbjct: 15782 MQTKGSDKWATC--ATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDL 15839
Query: 900 VKPPGLV-----------QDLHVSDS--SNSSISLAWREPAEGDPPSGYILEMRAEDTKE 946
V PP +DL V + ++ W + + P + AE T+
Sbjct: 15840 VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWH---KDNVPLKQTTRVNAESTEN 15896
Query: 947 WSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE-LDKGVRAMPPPAAPKFD 1005
S T I C G + ++ N A GE +E L+ V P P
Sbjct: 15897 NSLLT---IKDACREDVG-------HYVVKLTNSA--GEAIETLNVIVLDKPGPPTGPVK 15944
Query: 1006 LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINST 1065
+ + + G GS + I +K T + ++ + +
Sbjct: 15945 MDEVTADSITLSWGPP----KYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRL 16000
Query: 1066 KRSDSGVYRILLQNEFGEARY-DIHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSP 1120
K +RI +N +G++ Y + VA + P PP + +++ + WN
Sbjct: 16001 KTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPI 16060
Query: 1121 DVQEDGEAHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
Y + +++ ++ W + + K+ TGL G +Y FRV A N +G +
Sbjct: 16061 SDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGK 16120
Query: 1180 P 1180
P
Sbjct: 16121 P 16121
Score = 187 bits (474), Expect = 8e-47
Identities = 184/687 (26%), Positives = 294/687 (42%), Gaps = 94/687 (13%)
Query: 560 QIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT------------ESEASVFIADPPTIDPS 607
+I K + + F G +Y FR K ES + I PP ++
Sbjct: 11547 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVE-- 11604
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
L+ ITV+VG T I +G+P P +TW K+G + E+RV + + + L I
Sbjct: 11605 -LDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQI 11663
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKD 727
VR D G ++ KN G A + ++VLDRP P Q +C + W+ P D
Sbjct: 11664 KEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCT-ISWENPLD 11722
Query: 728 NGGRPVTQFIVERRAVGKKSW-IKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSD 786
NGG +T FIVE R +K W I +V ++ + E Y FR+ A N GV
Sbjct: 11723 NGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNE---YYFRVCAENKVGVGP 11779
Query: 787 PLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGS 845
+ET+ + A NPI+ PG + D K V + W P DGG+P L Y VERR KGS
Sbjct: 11780 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11839
Query: 846 NLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL 905
+ W V+K I+ T VD +E+ YEFRV N+ G V + VV K+ ++ P
Sbjct: 11840 DDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVVKEDLQKP-- 11896
Query: 906 VQDLHVSD----SSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT 961
V DL +S + +I L E P + + +D + ++ ++ I +
Sbjct: 11897 VLDLKLSGVLTVKAGDTIRL---EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADS 11953
Query: 962 VGGLIERQKYF----FRIRAVNEAG----------VGEP----------VELDKGVRAMP 997
+ + K + + A N AG + +P V D+
Sbjct: 11954 SKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWD 12013
Query: 998 PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNH 1057
P P+ D ++++++ + T + + +S + V T G T+T+
Sbjct: 12014 P---PEDDGGCEIQNYILEKCETKRMVWSTYSAT-----------VLTPG-TTVTRLIEG 12058
Query: 1058 SQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRLFEEVPNTV 1112
+++ ++R+ +N+ G E++ I D P P + + +
Sbjct: 12059 NEY-----------IFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEM 12107
Query: 1113 TLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGRKYYFRV 1169
T+ WN P + G++ Y + K++ + W + + V LLP +Y FRV
Sbjct: 12108 TVVWN--PPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRV 12165
Query: 1170 VARNEIGDSEP-LDSRDTWLINKDQIQ 1195
A NEIG EP L SR ++ KD I+
Sbjct: 12166 KAENEIGIGEPSLPSRP--VVAKDPIE 12190
Score = 185 bits (470), Expect = 2e-46
Identities = 136/460 (29%), Positives = 206/460 (44%), Gaps = 20/460 (4%)
Query: 730 GRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE 789
GRP + R ++I E T S + + A ++ + NS G
Sbjct: 17745 GRPTPEITWSREEGEFTDKVQI-EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 17803
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
T +V ++ PG V +V K++ + W P DGGA V Y++++R+ +
Sbjct: 17804 TVKV-----LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYA 17858
Query: 850 PVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDL 909
V+ T V+ L E Y FRV+A N+ G G P +V A +P PPG V
Sbjct: 17859 NVSSK-CSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVT-- 17915
Query: 910 HVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIE 967
++D S +S SL W +P G GY++EM+ + T++WS + + T GL
Sbjct: 17916 -LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVT--GLSS 17972
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
Q+Y FR++A NE G +P L V A P L S ++AG L I
Sbjct: 17973 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYS---IQAGEDLKIEIP 18029
Query: 1028 FSGSPPPDVIWQKDGVPTKG--RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR 1085
G P P++ W KDG P K R + ++ + I + D G Y + N G A
Sbjct: 18030 VIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTAT 18089
Query: 1086 YDIHVRVADFPRPPTNLRLFEEVP-NTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
++ V V + P PP F+EV + V ++W ++YI+ KRD +T TW+
Sbjct: 18090 ENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHM 18149
Query: 1145 AAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ V +T L G +Y FR+ A N G S PLDS+
Sbjct: 18150 VSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSK 18189
Score = 184 bits (467), Expect = 5e-46
Identities = 129/458 (28%), Positives = 206/458 (44%), Gaps = 17/458 (3%)
Query: 732 PVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE 791
P + + R + +++ I+ + + + + +G + +LA N G E +
Sbjct: 10249 PTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV---YSLLAKNEAG-----ERK 10300
Query: 792 EVFAGNPIEPPGFASQPQVT-DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP 850
+ + ++ PG P + ++T E+ +TW +P DGG+P+ Y++E+R+ W P
Sbjct: 10301 KTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTP 10360
Query: 851 VNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLH 910
V + TV GL++ Y FR+ A N G G S ++V ++P+ P +DL
Sbjct: 10361 VTYT-VTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE 10419
Query: 911 VSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
V + + ++++L W P G Y+LE R T+++ K T + YTV GL E
Sbjct: 10420 VKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEG 10479
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAF 1028
Y +R+ AVN G G+P K + A P L R K + +R G A + +
Sbjct: 10480 DTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDK--LTIRVGEAFALTGRY 10537
Query: 1029 SGSPPPDVIWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
SG P P V W KD V R I + KRSDSG Y ++++N G +
Sbjct: 10538 SGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKG 10597
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNT-VTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTA 1145
V V D P PP F+EV + ++W D +YII K++ W
Sbjct: 10598 FCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV 10657
Query: 1146 AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
V+ LL G+ Y FR+ A N G S+PL S
Sbjct: 10658 TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVS 10695
Score = 183 bits (465), Expect = 8e-46
Identities = 173/660 (26%), Positives = 266/660 (40%), Gaps = 74/660 (11%)
Query: 582 KYTFRAKGT----ESEASVFIADPPTID----PSVLEALAAH-AITVKVGHTAHIKVPFR 632
KY FR K ESE S + P D P V + A + K G I +
Sbjct: 9471 KYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIK 9530
Query: 633 GKPLPKVTW---------YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLK 683
G+P PK +W KDG+ E+ +E E+ +++ I C R +G + K
Sbjct: 9531 GRPTPKSSWEFDGKAKKAMKDGVHDIPED-AQLETAENSSVIIIPECKRSHTGKYSITAK 9589
Query: 684 NDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAV 743
N G TA + V+D P PP+ GSC + WK P D+GG + +++E+R +
Sbjct: 9590 NKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSC-RLSWKMPDDDGGDRIKGYVIEKRTI 9648
Query: 744 GKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLET-EEVFAGNPIEPP 802
K+W K+ G T + + E + Y FR+ A N G+ P+ET + A +PI PP
Sbjct: 9649 DGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIYPP 9707
Query: 803 GFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE-------RRKKGSNLWVPVNKDP 855
+ ++ +TK V ++W P DGG+PV YIVE KK + W NK
Sbjct: 9708 DPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEA--WRQCNKRD 9765
Query: 856 IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPG--LVQDLHVSD 913
++ + TV+ L+E EYEFRV AVN AG +PS + P PP L + + V +
Sbjct: 9766 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 9825
Query: 914 SSNSSI----------SLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVG 963
+N +I +L W + P + E + K+ + TC V
Sbjct: 9826 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDN-------KEPVLYDTHVNKLVVDDTCTLVI 9878
Query: 964 GLIERQKY-FFRIRAVNEAGVGEPVELDKGVRAMP-PPAAPKFDLSARLKSHMVVRAGTA 1021
R + I AVN G E+ V P PP P + +S + +
Sbjct: 9879 PQSRRSDTGLYTITAVNNLGTASK-EMRLNVLGRPGPPVGP-----IKFESVSADQMTLS 9932
Query: 1022 LCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEF 1081
GS + + +K K ++ + I V+RI+ QN++
Sbjct: 9933 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKY 9992
Query: 1082 G-----EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRD 1136
G ++ + + P P + N++T+ W Y + +D
Sbjct: 9993 GIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKD 10052
Query: 1137 ASTATWYTA-----AERVFSNKYTVTGLLPGRKYYFRVVARNEIG------DSEPLDSRD 1185
++ W Y VTGL+ G Y FRV A N G S+P +RD
Sbjct: 10053 TTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARD 10112
Score = 182 bits (463), Expect = 1e-45
Identities = 168/649 (25%), Positives = 276/649 (42%), Gaps = 83/649 (12%)
Query: 582 KYTFRAKGTESEASVFIADPPTIDPSV------------LEALAAHAITVKVGHTAHIKV 629
+Y FR SE + +P T+ SV L+A + ++ T + V
Sbjct: 18768 EYNFRICAINSEG---VGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFV 18824
Query: 630 PFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA 689
+G+P P+V W K +T+ R +E +L I N R DSG L L+N+ GS
Sbjct: 18825 TIKGRPEPEVKWEKAEGILTD--RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSK 18882
Query: 690 TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
TA +++ VLD P P + E+ V + W+ P +GG +T +IVE+R +K++
Sbjct: 18883 TAFVNVRVLDSPSAPVN-LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18941
Query: 750 KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQP 808
I K T F ++EG +Y FR+LA N G+ P ET E V P PPG +
Sbjct: 18942 TITNNCTKTT-FRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVT-- 18998
Query: 809 QVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
+ DVT+ TI W P DGG+ + GY+VE + KGS W + ++ + T+ GL
Sbjct: 18999 -LVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTA 19055
Query: 869 DTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE 928
EY FRV AVN+ G P V+A+D P + H + ++ RE +
Sbjct: 19056 GEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH-------TFNVKAREQLK 19108
Query: 929 GDPPSGYILEMRAEDTKEWSK-------CTKIPISG----TCYTVGGLIERQKYFFRIRA 977
D P + R + T W K T++ +S T ++ + + +
Sbjct: 19109 IDVP----FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV 19164
Query: 978 VNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP--- 1033
N AG + P+ + V P P P +R C S +PP
Sbjct: 19165 SNSAGSITVPITII--VLDRPGPPGP-------------IRIDEVSCDSITISWNPPEYD 19209
Query: 1034 -----PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY-D 1087
+ I +K + ++++ + I +R+ +N +G++ Y +
Sbjct: 19210 GGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE 19269
Query: 1088 IHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWY 1143
VA++ P PP ++ +T+ +TW + Y + ++ S+ W
Sbjct: 19270 SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWS 19329
Query: 1144 TAAERVFSN-KYTVTGLLPGRKYYFRVVARNEIG------DSEPLDSRD 1185
A + + ++ + V+GL G Y +RV A N G EP+ +RD
Sbjct: 19330 KANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARD 19378
Score = 176 bits (447), Expect = 1e-43
Identities = 152/630 (24%), Positives = 264/630 (41%), Gaps = 70/630 (11%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ + E ++ + + WK P D+GG +T + VERR W++ +
Sbjct: 14267 PGPPE-KPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLR 14325
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVTKEAVT 819
++EG Y+FR+ A N G+ P E ++ V + PPG S P VTD TK++ +
Sbjct: 14326 CKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSAS 14385
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVP-VNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
+ W P DGG + GY+VE +K G W+ ++ T+ V L +Y FR+ A
Sbjct: 14386 LAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14445
Query: 879 VNKAGPGQPSV-PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPP----- 932
+N AG G+P+V P +V ++ L +L + + +S+ P +G P
Sbjct: 14446 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTW 14505
Query: 933 --SGYILEMRA--EDTKEWS-----KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV 983
L+ RA E+T+ ++ +C + T+ ++ F +R ++ G
Sbjct: 14506 TKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14565
Query: 984 G---EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK 1040
P ++ K + P D +R+ +++V +K
Sbjct: 14566 VLNLRPTDITKDSVTLHWDL-PLIDGGSRITNYIV-----------------------EK 14601
Query: 1041 DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPR 1097
K T T + + + +R++ +NE+G V+ ++ P
Sbjct: 14602 REATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS 14661
Query: 1098 PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKY 1154
PP +L + + +TV+L W P + DG + Y+I + + W T V +
Sbjct: 14662 PPDSLNIMDITKSTVSLAW---PKPKHDGGSKITGYVIEAQRKGSDQW-THITTVKGLEC 14717
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPR 1214
V L G +Y F+V+A N G S P +SR + + + +L + Y+K A
Sbjct: 14718 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLR-GIYQKLVIAKA-- 14774
Query: 1215 FVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPT 1274
G + + LG P+PTVT KGD + + + +T+ L I
Sbjct: 14775 ------------GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINE 14822
Query: 1275 CTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
C DSG Y + N +G+ T+ V+D
Sbjct: 14823 CVRSDSGPYPLTARNIVGEVGDVITIQVHD 14852
Score = 174 bits (442), Expect = 4e-43
Identities = 163/600 (27%), Positives = 259/600 (43%), Gaps = 61/600 (10%)
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L+A + ++ G T + VP +G+P PK+TW K + + + + ++ + L
Sbjct: 13390 LDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCE 13449
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
N + D+G +L L+N G T+ + VLD P PP V E+S ++ W+ P +
Sbjct: 13450 NVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVN-VTVKEISKDSAYVTWEPPIID 13508
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG P+ ++V++R +KSW + K T+F +EEGK+Y FR+ A N G+ DP
Sbjct: 13509 GGSPIINYVVQKRDAERKSWSTVTTECSK-TSFRVANLEEGKSYFFRVFAENEYGIGDPG 13567
Query: 789 ETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW 848
ET + + + PG +V V+K + +I W P DGG+ ++GY+V+ + N W
Sbjct: 13568 ETRDAVKAS--QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTE-ENKW 13624
Query: 849 VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL--- 905
V K + + L E EY FRV A N+ G G PS +VVA+D V P L
Sbjct: 13625 QRVMKS--LSLQYSAKDLTEGKEYTFRVSAENENGEGTPS--EITVVARDDVVAPDLDLK 13680
Query: 906 -VQDLHVSDSSNSSISLAWREPAEGDP-PSGYILEMRAEDTKEWSKCTKIPIS--GTCYT 961
+ DL NS+ L + P +G P PS + + ED + S T
Sbjct: 13681 GLPDLCYLAKENSNFRL--KIPIKGKPAPS--VSWKKGEDPLATDTRVSVESSAVNTTLI 13736
Query: 962 VGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAP-KFDLSARLKSHMVVRAGT 1020
V + + I N AG E K V P P KFD + A T
Sbjct: 13737 VYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFD-------EVTAEAMT 13789
Query: 1021 ALCIHAAFSGSPPPD---------VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSG 1071
+PP D ++ ++D V K T + + F +
Sbjct: 13790 -------LKWAPPKDDGGSEITNYILEKRDSVNNKW-VTCASAVQKTTFRVTRLHEGMEY 13841
Query: 1072 VYRILLQNEFG----------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+R+ +N++G AR+ V D P PP + + ++V+LTW
Sbjct: 13842 TFRVSAENKYGVGEGLKSEPIVARHPFD--VPDAPPPP---NIVDVRHDSVSLTWTDPKK 13896
Query: 1122 VQEDGEAHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
Y + ++ ++ W A + + + VTGL G +Y FRV+A N G +P
Sbjct: 13897 TGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKP 13956
Score = 174 bits (440), Expect = 7e-43
Identities = 143/479 (29%), Positives = 208/479 (43%), Gaps = 77/479 (16%)
Query: 743 VGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPP 802
V KKS + I VD K ++ T +E AVN G V N ++ P
Sbjct: 7437 VPKKSTVTI--VDSKRSDTGTYIIE----------AVNVCG-----RATAVVEVNVLDKP 7479
Query: 803 GFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCT 862
G + +TDVT E+ +TWN P DGG+ + Y+VERR S +W ++ ++ T
Sbjct: 7480 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSST-VKDTNFK 7538
Query: 863 VDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
L+ + EY FRV A N G G+P V +S + AK PPG L SD + +++L
Sbjct: 7539 ATKLIPNKEYIFRVAAENMYGVGEP-VQASPITAKYQFDPPGPPTRLEPSDITKDAVTLT 7597
Query: 923 WREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNE 980
W EP + G P +GY +E DT +W +C K+P+ T Y V GL ++KY FR+ A N
Sbjct: 7598 WCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENL 7657
Query: 981 AGVG------EPVELDKGVRAMPPPAAP-----------------KFDLSARLKSHMV-- 1015
AG G EP+ + + PP P + D A+++S+++
Sbjct: 7658 AGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEM 7717
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
++ GT + A +GVPT +Q L+ +R+
Sbjct: 7718 LKTGTDEWVRVA-------------EGVPT------------TQHLLPGLMEGQEYSFRV 7752
Query: 1076 LLQNEFGEARYD-----IHVRVADFP-RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH 1129
N+ GE+ + R +P PP L + NT L W +
Sbjct: 7753 RAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITN 7812
Query: 1130 YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWL 1188
YI+ KRD W T V K TVT L G Y FRV A N IG S+ + D+ L
Sbjct: 7813 YIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVL 7871
Score = 174 bits (440), Expect = 7e-43
Identities = 141/466 (30%), Positives = 208/466 (44%), Gaps = 32/466 (6%)
Query: 730 GRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFST-------NKVEEGKAYQFRILAVNSE 782
GRP + + V + +IG +D K T+F T NK + GK + + NS
Sbjct: 13414 GRPPPKITWSKPNVNLRD--RIG-LDIKSTDFDTFLRCENVNKYDAGK---YILTLENSC 13467
Query: 783 GVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRK 842
G + E ++ PG V +++K++ +TW P DGG+P++ Y+V++R
Sbjct: 13468 G-----KKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRD 13522
Query: 843 KGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKP 902
W V + T V L E Y FRV A N+ G G P +V A +
Sbjct: 13523 AERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKAS---QT 13578
Query: 903 PGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCY 960
PG V DL V S SS S+ W++P G GY+++ E+ K W + K Y
Sbjct: 13579 PGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKS--LSLQY 13635
Query: 961 TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGT 1020
+ L E ++Y FR+ A NE G G P E+ V A AP DL + + +
Sbjct: 13636 SAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENS 13693
Query: 1021 ALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
+ G P P V W+K D + T R ++ S ++ ++ ++SD+G Y I L+
Sbjct: 13694 NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLK 13753
Query: 1079 NEFGEARYDIHVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDA 1137
N G I ++V P PT F+EV +TL W D +YI+ KRD+
Sbjct: 13754 NVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13813
Query: 1138 STATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
W T A V + VT L G +Y FRV A N+ G E L S
Sbjct: 13814 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKS 13859
Score = 172 bits (437), Expect = 1e-42
Identities = 175/656 (26%), Positives = 265/656 (40%), Gaps = 95/656 (14%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG-----EVD 755
P PP G+ + L + + + W P DNGG P+T + +E+R G W ++ +V
Sbjct: 9294 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9352
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVT 814
K F+ ++ EG YQFR +A+N+ G+ P E ++ AG+PI PPG S P+V D T
Sbjct: 9353 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKT 9412
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLLEDTEY 872
K ++++ W P +DGG+P+ GYIVE +++G+ W VN+ I +C V L E +Y
Sbjct: 9413 KSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKY 9472
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA----E 928
FRV AVN+AG +PS + + A D + P + D+ D R PA
Sbjct: 9473 RFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGR 9532
Query: 929 GDPPSGYILEMRAE----------------DTKEWSKCTKIPISGTCYTVGGLIERQKYF 972
P S + + +A+ +T E S IP +T KY
Sbjct: 9533 PTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT-------GKY- 9584
Query: 973 FRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC--IHAAFSG 1030
I A N+AG + V+ M P PK LK + R L + G
Sbjct: 9585 -SITAKNKAG---QKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDDDGG 9635
Query: 1031 SPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG-------- 1082
+ +K + K + + F++ +R+ +N FG
Sbjct: 9636 DRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETI 9695
Query: 1083 ---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM-----K 1134
AR I+ P PP L++ NTV L+W + HYI+
Sbjct: 9696 QRTTARDPIYP-----PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDP 9750
Query: 1135 RDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQ 1193
W +R V ++TV L+ G +Y FRV A N G S+P
Sbjct: 9751 TGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP------------- 9797
Query: 1194 IQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNI 1253
SA + P + + P + + V G + + G P PT+T +K
Sbjct: 9798 ----SATVGPCDCQR-PDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKK 9852
Query: 1254 TANSKFWYNST-------SGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
N + T CTLVIP D+G Y++ N LG L V
Sbjct: 9853 PDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9908
Score = 172 bits (437), Expect = 1e-42
Identities = 178/792 (22%), Positives = 321/792 (40%), Gaps = 74/792 (9%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFI------A 599
W+K +E+++ ++I L G Y +AK E SV +
Sbjct: 16272 WIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDR 16331
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
P P V+ + A T+ K P + + + + E + ++
Sbjct: 16332 PGPPEGPVVISGVTAEKCTLAW------KPPLQDGGSDIINYIVERRETSRLVWTVVDAN 16385
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHG--------SATATLHLSVLDRPKPPQGRVEFL 711
++ + + + N +G A V D PK P E
Sbjct: 16386 VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP----EVT 16441
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK-----IGEVDGKVTNFSTNKV 766
++ + + W+ P +GG + +++E+R W + IGE+ +VT N
Sbjct: 16442 TVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH- 16500
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
Y+FR+ A N+ G+S+P A +PI PG + P+V D+T+ +V ++W+ P
Sbjct: 16501 ----DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKP 16556
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLEDTEYEFRVIAVNKAGP 884
DGG + GYIVE+ W I T V+ LLE EY FR+ A+NKAG
Sbjct: 16557 IYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGV 16616
Query: 885 GQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN--SSISLAWREPAEGDPPSGYILEMRAE 942
G+ + ++ ++ ++ P + DL + N + SL P +G P + + + +
Sbjct: 16617 GEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRP-TPEVKWGKVD 16675
Query: 943 DTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAP 1002
+ + S T + + + + N +G VR + P+ P
Sbjct: 16676 GEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVT---VRVLDTPSPP 16732
Query: 1003 KFDLSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
LK + + ++ GS + I +K K + + + + +
Sbjct: 16733 -----VNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSW 16787
Query: 1061 LINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWN 1117
I+ + S +R+ +NE+G A+ ++VA+ P+PP + + + N+V+L+W
Sbjct: 16788 KIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWT 16847
Query: 1118 HSPDVQEDGEAHYI--IMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEI 1175
+ DG + I I++ A + ++ RV S + +T L G +Y FRVVA NE
Sbjct: 16848 KP---EHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEK 16904
Query: 1176 GDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCA 1235
G S+P S ++ KD + + K P F + ++V GQD +
Sbjct: 16905 GRSDPR-SLAVPIVAKDLVIEPDVK------------PAFSS----YSVQVGQDLKIEVP 16947
Query: 1236 FLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDR 1295
G P+PT+T K + + ++ + + TL I D G Y + V N +G+
Sbjct: 16948 ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKT 17007
Query: 1296 SSCTLTVYDKDD 1307
+S + DK D
Sbjct: 17008 ASIEIVTLDKPD 17019
Score = 171 bits (432), Expect = 6e-42
Identities = 170/661 (25%), Positives = 275/661 (41%), Gaps = 101/661 (15%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP + ++++ V +KW+ PK++GGRP+ ++++E++ W+K G+ G N
Sbjct: 7879 PGPPYA-LAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 7937
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFA-GNPIEPPGFASQPQVTDVTKEAVT 819
F V EG QF++ A N GV P E E+ + +P PP VTD ++ +
Sbjct: 7938 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 7997
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVD-GLLEDTEYEFRVIA 878
I W P ++GG+P++GY VE G+ W+ VN PI+ K V+ G++ D EY RV A
Sbjct: 7998 IAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRA 8057
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGL---VQDLHVSDSSNSSISLAWREPAEGDPPSGY 935
VN G +PS S +VVAKDP P + D+ V + SI + +R A P +
Sbjct: 8058 VNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFR--AVPVPTVSW 8115
Query: 936 ILEMRAEDTKEWSKCTKIPISGTCYT----VGGLIERQKYFFRIRAVNEAGVGEPVELDK 991
+D KE ++ + + V + + I N+ G ++
Sbjct: 8116 -----HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG-SATASINV 8169
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA-FSGSPP--PDVIWQKDGVPTKGR 1048
V +P P +K+ + ++ L F G P V+ +++ GR
Sbjct: 8170 KVIGLPGPCKD-------IKASDITKSSCKLTWEPPEFDGGTPILHYVLERREA----GR 8218
Query: 1049 ET---ITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR---VADFPR----P 1098
T + +N + + + +R+ N+ G Y I ++ +A P+ P
Sbjct: 8219 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY-IELKNPVIAQDPKQPPDP 8277
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSN-KYT 1155
P ++ + +T+TW P + + G YII K W E + YT
Sbjct: 8278 PVDVEVHNPTAEAMTITWK--PPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYT 8335
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
GL G++Y FRV A N G SEP S P + D AP+
Sbjct: 8336 AKGLEEGKEYQFRVRAENAAGISEP-----------------SRATPPTKAVDPIDAPKV 8378
Query: 1216 V--TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWY------------ 1261
+ T L+ V RG + + + G+P PT+T K D N+ +
Sbjct: 8379 ILRTSLE---VKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE 8434
Query: 1262 ------------------NSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVY 1303
NS G L + D G Y + VEN+ G ++ CT++V
Sbjct: 8435 VQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8494
Query: 1304 D 1304
D
Sbjct: 8495 D 8495
Score = 169 bits (427), Expect = 2e-41
Identities = 217/939 (23%), Positives = 367/939 (39%), Gaps = 112/939 (11%)
Query: 430 VKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
VK R + ++ + T+ W+KDGQ L T+ +++ L I++A D G Y
Sbjct: 19101 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19160
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLA---TVKSGMSDVHAATGSPAEL---CVVLNDEKV 542
+ T IV + D + +P E C + N
Sbjct: 19161 ELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISN---- 19216
Query: 543 EGVWLKDGKEITDLPGMQIVKQGAVH---KLIFPSMGPEHEGKYTFR---AKGTESEASV 596
++ + KE T IV Q K++ + G E++ + K + SE+S
Sbjct: 19217 ---YIVEKKETTSTT-WHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSA 19272
Query: 597 FIADPPTIDPS------VLEA-----LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+A+ P P V+ A L + V G + I K + W K
Sbjct: 19273 VVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKAN 19332
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
+ + ++ + G D+ L+ E+ I G + + P P
Sbjct: 19333 KILIADTQMKVS-GLDEGLMYEYRVYAENIAGI--------GKCSKSCEPVPARDPCDPP 19383
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNK 765
G+ E ++ V +KW P +GG +T +IVERR + W+K + + T F +
Sbjct: 19384 GQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTE 19443
Query: 766 VEEGKAYQFRILAVNS-EGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDV--TKEAVTIT 821
+ E + Y+FR+ A N+ + VS+P E T + + +EPP + DV K +
Sbjct: 19444 LTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLK 19503
Query: 822 WNAPTQDGGAPVLGYI---VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
NA PV+ + +E ++ + + + K D + DT + +
Sbjct: 19504 INADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVK---DCIRRDTG---QYVL 19557
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYI 936
K G SV + V P P G L ++ + SL+W P E G YI
Sbjct: 19558 TLKNVAGTRSVAVNCKVLDKPGPPAG---PLEINGLTAEKCSLSWGRPQEDGGADIDYYI 19614
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
+E R W+ C + T V L++ +Y FR+ VN+ GVGEP+E ++A+
Sbjct: 19615 VEKRETSHLAWTICEG-ELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLE-SVAIKAL 19672
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT---- 1052
P P S + S V + LC P D + G + RE +
Sbjct: 19673 DPFTVPSPPTSLEITS--VTKESMTLCW-----SRPESDGGSEISGYIIERREKNSLRWV 19725
Query: 1053 --KSKNHSQFLINST--KRSDSGVYRILLQNEFG---EARYDIHVRVAD---FPRPPTNL 1102
K + ST + YR+ +N G + +R D P PP+
Sbjct: 19726 RVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKP 19785
Query: 1103 RLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYTVTGL 1159
++ + T+T+ W DG A Y + + + W T+ + + +YT++GL
Sbjct: 19786 KIVDSGKTTITIAWVKP---LFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGL 19842
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSRDTWLI---NKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
G +Y FRV + N++G S+P DS D + ++ + D+ ++++
Sbjct: 19843 TTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMR-------------- 19888
Query: 1217 TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
K V G TMT F G P P V K D ++ ++ + ++T +L I
Sbjct: 19889 ---KTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL--RTRAYVDTTDSRTSLTIENAN 19943
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASIT 1315
DSG Y++ ++N L +S TL V D +IT
Sbjct: 19944 RNDSGKYTLTIQNVL--SAASLTLVVKVLDTPGPPTNIT 19980
Score = 167 bits (424), Expect = 5e-41
Identities = 248/1114 (22%), Positives = 419/1114 (37%), Gaps = 162/1114 (14%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRM 317
P K+ W K LR + L D+K L NVN DAG Y L S G K
Sbjct: 13416 PPPKITWSKPNVNLRDRIGL---DIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEY 13472
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEP---------NFVWKFNGKELK 368
+ + VLD P PV VT ++ + ++ + P N+V + E K
Sbjct: 13473 TIVVKVLDTP------GPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERK 13526
Query: 369 R---------DDKYEITVSEDGLTHTLKI---KDARLSDSGEFSAEAGNLVQKAQLTIDR 416
+ + E+G ++ ++ + + D GE + +A Q +D
Sbjct: 13527 SWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGE-TRDAVKASQTPGPVVD- 13584
Query: 417 IPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKK---DGQLLMHGTKYSMNHEGKRA 473
+K RS + C ++ WKK DG + G E +
Sbjct: 13585 -------------LKVRSVSKSSC-------SIGWKKPHSDGGSRIIGYVVDFLTEENKW 13624
Query: 474 ELIIEDAQL-------SDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKS----GMSD 522
+ +++ L ++G EYT + + E + I V G+ D
Sbjct: 13625 QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPD 13684
Query: 523 VH--AATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHK-LIFPSMGPEH 579
+ A S L + + + V K G++ V+ AV+ LI
Sbjct: 13685 LCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSD 13744
Query: 580 EGKYTFRAKGT----ESEASVFIADPPTID--PSVLEALAAHAITVKVGHTAHIKVPFRG 633
GKYT K E S+ + P I P + + A A+T+K P +
Sbjct: 13745 AGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWA-------PPKD 13797
Query: 634 KPLPKVTWY-KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA--- 689
++T Y + + + V+ + ++ + +N +G
Sbjct: 13798 DGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGL 13857
Query: 690 -----TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVG 744
A V D P PP +++ V + W PK GG P+T + +E +
Sbjct: 13858 KSEPIVARHPFDVPDAPPPPN----IVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 13913
Query: 745 KKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP-LETEEVFAGNPIEPPG 803
W + + ++ +F + EG Y+FR++A+N GV P L +E V A +PI+PPG
Sbjct: 13914 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 13973
Query: 804 FASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTV 863
+P+V ++T+ +VT+ W P DGG + GYIVE+R S W+ N + TV
Sbjct: 13974 ---KPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTV 14030
Query: 864 DGLLEDTEYEFRVIAVNKAGP-GQPSVPSSSVVAKDPVKPPGLVQDLHVSD-----SSNS 917
L+E +YEFR+ A N AG PS + +++ KD + P +V D + D + ++
Sbjct: 14031 TDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDT 14090
Query: 918 SISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRA 977
+ A + P S + + + ++ T P S + T+ + + I A
Sbjct: 14091 IVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKDAGEYTITA 14149
Query: 978 VNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
N G E V++ V +P P P + + +A GSP
Sbjct: 14150 TNPFGTKVEHVKVT--VLDVPGPPGP-----VEISNVSAEKATLTWTPPLEDGGSPIKSY 14202
Query: 1037 IWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR--YDIHVRVAD 1094
I +K +++ + + + + ++R+ N +G+ V++ D
Sbjct: 14203 ILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVD 14262
Query: 1095 F---PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFS 1151
P PP + NT T++W D Y + +R+ + W A + S
Sbjct: 14263 RFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS 14322
Query: 1152 N-KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWR 1210
+ + VTGL G Y FRV A N G P ++ D+ L+ KD
Sbjct: 14323 DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLM-----------------KDAA 14365
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNIT--------ANSKFWYN 1262
+ P P PH D T A L +P Y G + IT + W
Sbjct: 14366 YPPG--PPSNPHVT----DTTKKSASLAWGKPH---YDGGLEITGYVVEHQKVGDEAWIK 14416
Query: 1263 STSG----VCTLVIPTCTLKDSGDYSVLVENELG 1292
T+G + V+P K+ ++ + N+ G
Sbjct: 14417 DTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14450
Score = 167 bits (423), Expect = 6e-41
Identities = 166/658 (25%), Positives = 277/658 (42%), Gaps = 63/658 (9%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
+++GA +KL ++ EG T +E +PP ++ L+ I +
Sbjct: 8761 IREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQ----EPPAVE---LDVSVKGGIQIMA 8813
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
G T I G+P+P W K+ E+ +++RV ++ ++ L I + +R+D G ++
Sbjct: 8814 GKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVIDNVGTKSELIIKDALRKDHGRYVIT 8872
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
N GS A + V D P P + C+ + W P+D+GG +T FI+ER+
Sbjct: 8873 ATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCL-LNWSDPEDDGGSEITGFIIERK 8931
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
+W + ++ + + + EG+ Y+FR++A N G P+E + A +P+ P
Sbjct: 8932 DAKMHTWRQ--PIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGP 8989
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
P + T+ TK +T+ W P +GG+P+ GYI+E+R+ + VNK T
Sbjct: 8990 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 9049
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
V+ L E YEFRV AVN+ G +PS+P + V+ D V PP + L V +I +
Sbjct: 9050 LVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEV-PPTIKLRLSV---RGDTIKV 9105
Query: 922 AWREPAEGDPPSGYILEMRAEDTKEWSK-------------CTKIPIS----GTCYTVGG 964
EP P L M EWSK TK +S T ++
Sbjct: 9106 KAGEPVH-IPADVTGLPM---PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPK 9161
Query: 965 LIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSAR---LKSHMVVRAGT 1020
+ K + + A N G V V ++ R PP D+ A L + G
Sbjct: 9162 AVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGG 9221
Query: 1021 ALCIHAAFSGSPPPDVIWQKDGVPTKGR-ETITKSKNHSQFLINSTKRSDSGVYRILLQN 1079
+ H VI ++D K E +T + ++ I + +R+ N
Sbjct: 9222 SEITHY---------VIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVN 9272
Query: 1080 EFG---EARYDIHVRVAD---FPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM 1133
++G E + D V + D P PP ++ ++ ++W D Y +
Sbjct: 9273 KYGISDECKSD-KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLE 9331
Query: 1134 KRDASTATWYTAAERVFSN------KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
KR+ + W + + ++ V LL G KY FR +A N G P + D
Sbjct: 9332 KREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSD 9389
Score = 165 bits (417), Expect = 3e-40
Identities = 163/635 (25%), Positives = 271/635 (42%), Gaps = 78/635 (12%)
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
+D +PP+ V ++S + V + W+ P +GG +T +IVERR + W K +
Sbjct: 20460 IDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20518
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEG-------VSDPLETEEVFAGNPIEPPGFASQPQV 810
T F + + + Y+FR+ A N+ G V P+ + + G I+ P +
Sbjct: 20519 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLP-----LEY 20573
Query: 811 TDVTK--EAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
T+V K ++ A AP + + + ++ +N V V + T L++
Sbjct: 20574 TEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCV-----ENTTDLASILIK 20628
Query: 869 DTE------YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
D + YE ++ N G ++ V D PPG + + I+L
Sbjct: 20629 DADRLNSGCYELKLR--NAMGSASATI---RVQILDKPGPPG--GPIEFKTVTAEKITLL 20681
Query: 923 WREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNE 980
WR PA+ G + YI+E R WS ++ + T +I+ +Y FR+RAVN+
Sbjct: 20682 WRPPADDGGAKITHYIVEKRETSRVVWSMVSE-HLEECIITTTKIIKGNEYIFRVRAVNK 20740
Query: 981 AGVGEPVELDKGV--RAMPPPAAPKF-DLSARLKSHMVVRAGTALCIHAAFSGSPPPDVI 1037
G+GEP+E D V A P P +++ K+ M V + A GS
Sbjct: 20741 YGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPI----ADGGSDISGYF 20796
Query: 1038 WQKDGVPTKGRETITKS--KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV--- 1092
+K + G + K ++ Q + T+ SD YR+ N G+ +
Sbjct: 20797 LEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKA 20855
Query: 1093 ---ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAE 1147
D P PP +R+ + +++TL W S V + G A Y++ R W T +
Sbjct: 20856 ADPIDPPGPPAKIRIADSTKSSITLGW--SKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20913
Query: 1148 R--VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYE 1205
+ V + +Y V+ L PG YYFRV A N G EP++ + P +
Sbjct: 20914 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNE-----------------PVQ 20956
Query: 1206 KKDWRHAPRFVTPLKPHTVL---RGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
KD AP + T + G+D + F G P PTVT K + N+ +++++
Sbjct: 20957 AKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE 21016
Query: 1263 STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSS 1297
+T L IP T D+G Y + +EN +G+ +SS
Sbjct: 21017 NTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSS 21051
Score = 165 bits (417), Expect = 3e-40
Identities = 205/927 (22%), Positives = 345/927 (37%), Gaps = 119/927 (12%)
Query: 441 ELTSKDVTLRWK---KDGQLLMHGTKYSMN-HEGKRAELIIEDAQLSDGGEYTVVAMQDG 496
++T + +TL+W +DG + G YS+ +G + +S+ +YTV + G
Sbjct: 21560 DVTRETITLKWNPPLRDGGSKIVG--YSIEKRQGNERWVRCNFTDVSEC-QYTVTGLSPG 21616
Query: 497 D----------------PTEYYSTAIVTVEERLATV----KSGMSDVHAATGSPAELCVV 536
D P S I+T +E + + + +G + +
Sbjct: 21617 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 21676
Query: 537 LNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT----E 591
+ V V W KDG EI M+I L +H G YT AK +
Sbjct: 21677 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 21736
Query: 592 SEASVFIADPP--TIDPSVLEALAAHAITV------KVGHTAHIKVPFRGKPLPKVTW-- 641
+E V + D P + P + +T+ G + ++ W
Sbjct: 21737 AEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWAL 21796
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP 701
+D E + + G + +S + G L D A + +V D P
Sbjct: 21797 IEDKCEAQSYTAIKLINGNEYQF-RVSAVNKFGVGRPL-----DSDPVVAQIQYTVPDAP 21850
Query: 702 KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK-IGEVDGKVTN 760
P+ ++G+ + + W P+ +GG + Q+I+ERR W+K I + T
Sbjct: 21851 GIPEPS----NITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETR 21906
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVT 819
F + EG Y+F ++A N+ GV + P+ PPG + +VTD +K V+
Sbjct: 21907 FKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVS 21966
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAV 879
+ W+ P DGG ++GYI+E K W VN + T+ TV L EY+FRV A+
Sbjct: 21967 LEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAI 22026
Query: 880 NKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDS----SNSSISL------------AW 923
N AG G + ++ A D + P L D + + + +SI L W
Sbjct: 22027 NGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVW 22086
Query: 924 REPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV 983
+P I + T C + TV + F ++ ++ G
Sbjct: 22087 SKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP 22146
Query: 984 GEPVELDKGVRAMPPPA--APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKD 1041
P+ R AP D AR+ ++V +K
Sbjct: 22147 PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVV-----------------------EKR 22183
Query: 1042 GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR-YDIH--VRVADFPRP 1098
+ + I++ F +N +R+ NE+G Y++ + + P P
Sbjct: 22184 EASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP 22243
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYT 1155
P L + + ++ L W PD DG + Y++ R + W A +T
Sbjct: 22244 PRRLDVVDTSKSSAVLAWL-KPD--HDGGSRITGYLLEMRQKGSDFWVEAGHTK-QLTFT 22299
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
V L+ +Y FRV A+N+ G SEP ++ + +I + QI+ +A L
Sbjct: 22300 VERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP-TADLTGITN--------- 22349
Query: 1216 VTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
+ T G T+ G P P VT ++ + + +T TL +
Sbjct: 22350 ----QLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 22405
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTV 1302
DSG Y + +EN G S T+ V
Sbjct: 22406 MRGDSGRYFLTLENTAGVKTFSVTVVV 22432
Score = 164 bits (416), Expect = 4e-40
Identities = 230/1109 (20%), Positives = 416/1109 (37%), Gaps = 125/1109 (11%)
Query: 268 WIKGTEPLRIQYSLGKYDVKQMGT------KYMLVISNVNMNDAGIYSL----SVGDKRM 317
++ G P + +++ + + Q T +VI N + G+YSL G+++
Sbjct: 10242 YVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKK 10301
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDK----- 372
+ + VLD P +T + + + + ++ + D +
Sbjct: 10302 TIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPV 10361
Query: 373 -YEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVK 431
Y +T + ++ K + E S G V+ ++ + R PI +++ VK
Sbjct: 10362 TYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVK 10421
Query: 432 ERSRACLECELTSKDVTLRWKKD----GQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGE 487
E +T VTL W G +++ S ++ + D LS +
Sbjct: 10422 E---------VTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSR--K 10470
Query: 488 YTVVAMQDGDPTEYYSTAI--------------VTVEERLA------------TVKSGMS 521
YTV +++GD EY +A+ +T ++ LA T++ G
Sbjct: 10471 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVG-- 10528
Query: 522 DVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEG 581
+ A TG + K + W KD ++ + I A L G
Sbjct: 10529 EAFALTGRYS------GKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSG 10582
Query: 582 KYTFRAKGTES------EASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKP 635
KY + + + +V P + P + + + + K P
Sbjct: 10583 KYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISW------KPPLDDGG 10636
Query: 636 LPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLH- 694
+ + EV ++ + + + +S + + + +N +G + +
Sbjct: 10637 SKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSD 10696
Query: 695 -LSVLDRPKPPQGRVEFL--ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKI 751
+ DR + P + + E++ + W P D GG+P+T +I+E+R K W ++
Sbjct: 10697 SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARV 10755
Query: 752 GEVD-GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQ 809
+ T F + EG Y+FR+ A N G+ DP ++ VFA +PI P P+
Sbjct: 10756 TKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPE 10815
Query: 810 VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLL 867
D T +V +TW P DGG+ +LGYIVE +K G W N P TK V GL
Sbjct: 10816 AIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLR 10875
Query: 868 EDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA 927
+ Y+FRV+AVN AG P+ V+ KD ++PP L+ D +++ + + R A
Sbjct: 10876 DGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSA 10935
Query: 928 --EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
+G P + D ++ P+ G+ + + + N AG
Sbjct: 10936 IIKGVPFPKVTWKKEDRDAPTKARIDVTPV-GSKLEIRNAAHEDGGIYSLTVENPAG--- 10991
Query: 986 PVELDKGVRAMPPPAAPK-FDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP 1044
+ V + P P+ ++S K + L GS + + ++ V
Sbjct: 10992 SKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPL----DDGGSVITNYVVERRDVA 11047
Query: 1045 TKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY---DIHVRVADF---PRP 1098
+ ++ + + ++R+ +N++G + ++ D P P
Sbjct: 11048 SAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGP 11107
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYT 1155
P +L + V+L WN PD DG + Y++ ++ T W + V + +
Sbjct: 11108 PKDLHHVDVDKTEVSLVWN-KPD--RDGGSPITGYLVEYQEEGTQDWIKF-KTVTNLECV 11163
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
VTGL G+ Y FRV A N +G P D + ++ EK
Sbjct: 11164 VTGLQQGKTYRFRVKAENIVGLGLP---------------DTTIPIECQEKLVPPSVELD 11208
Query: 1216 VTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
V ++ V G G P PT I + + + + L I C
Sbjct: 11209 VKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNC 11268
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
+D+G+Y + V N G + LTV D
Sbjct: 11269 LRRDTGEYQITVSNAAGSKTVAVHLTVLD 11297
Score = 163 bits (412), Expect = 1e-39
Identities = 149/604 (24%), Positives = 259/604 (42%), Gaps = 43/604 (7%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
I + P ID L+ ++ K G + +PF+G+P P VTW KD + + R S+E
Sbjct: 20960 ILEAPEID---LDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE 21016
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGS-ATATLHLSVLDRPKPPQGRVEFLELSGS 716
+ +LLTI R D+G +L ++N G ++T+ + VLD P Q +++ +S
Sbjct: 21017 NTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQ-KLQVKHVSRG 21075
Query: 717 CVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRI 776
V + W P +GG P+ +++E+R K++W + T+F + E + FR+
Sbjct: 21076 TVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSS-TSFKLIDLSEKTPFFFRV 21134
Query: 777 LAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGY 836
LA N G+ +P ET E E P + D TK +V ++W P DGG+ + Y
Sbjct: 21135 LAENEIGIGEPCETTEPV--KAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY 21192
Query: 837 IVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVA 896
+VER+ KG W + + V L E + EFRV A N+ G P V +
Sbjct: 21193 VVERKGKGEQTWSHAGIS--KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP-VTIGPITV 21249
Query: 897 KDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPIS 956
K+ + P ++ +SD + +++ + P + + + + W K +P+
Sbjct: 21250 KELIITP----EVDLSDIPGAQVTVRIGHNVHLELP----YKGKPKPSISWLK-DGLPLK 21300
Query: 957 GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV--RAMP-------PPAAPKFDLS 1007
+ + E + A E G V LD V A+P PP+ PK +
Sbjct: 21301 ESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIR 21360
Query: 1008 -ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTK 1066
+K+ V+ + + G +K + + S + F + +
Sbjct: 21361 FDEIKADSVILSWD---VPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLV 21417
Query: 1067 RSDSGVYRILLQNEFGEAR---YDIHVRVADF--PRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+ +R+ +N +G ++ I V F P PP ++ + ++LTW+
Sbjct: 21418 KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWD--AP 21475
Query: 1122 VQEDGE--AHYIIMKRDASTATWYTA-AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
V + G + + K++ ++ W + +Y TGL+ G Y FRV A N G S
Sbjct: 21476 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21535
Query: 1179 EPLD 1182
P D
Sbjct: 21536 SPSD 21539
Score = 162 bits (409), Expect = 3e-39
Identities = 153/668 (22%), Positives = 271/668 (40%), Gaps = 55/668 (8%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+F+ + VTA E + AVF + + + W + + + + K H +
Sbjct: 5625 KFLTPLKDVTAKEKESAVFTVELSHD-NIRVKWFKNDQ-RLHTTRSVSMQDEGKTHSITF 5682
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTV---------SLLVTEGQEKMDF------------ 166
+ L+ DD+ + A ++A TV L G EK +
Sbjct: 5683 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5742
Query: 167 KKMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMK 226
K K P K A+ K+ + IL K K D + + G G K
Sbjct: 5743 VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDKTSG--------K 5794
Query: 227 KKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIW-IKGTEPLRIQYSLGKYD 285
+E I++++PL E T F+ E+ + ++ W +KG L+ +
Sbjct: 5795 LDIEDREIKLVRPLHSVEVMETETARFET--EISEDDIHANWKLKGEALLQTP----DCE 5848
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
+K+ G + LV+ N ++ G + + SA L V + L +K V VT +TA
Sbjct: 5849 IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETA 5908
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
F+ LS ++ W GK+L+ DK + +G HTL ++D +L D+GE A +
Sbjct: 5909 TFDCELSYEDIPVEWYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5966
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
A L + P++F L++ V+E + A LECE++ ++ ++W K+G ++ KY
Sbjct: 5967 FKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYE 6026
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ +G+ +L+I D D YT D ++ ++ + V ++D+
Sbjct: 6027 IVADGRVRKLVIHDCTPEDIKTYTC------DAKDFKTSCNLNVVPPHVEFLRPLTDLQV 6080
Query: 526 ATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A L+ E + W KDG EI I+ +GAV L+ + E +Y+
Sbjct: 6081 REKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC 6140
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFR-GKPLPKVTWYKD 644
+ + + + + + + ++V T IK+ KP +V WYK
Sbjct: 6141 EVRTARTSGMLTVLEEEAV-------FTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKG 6193
Query: 645 GMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
E+ E R + + +L I N ED+G +L + +H + P
Sbjct: 6194 DEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKP 6253
Query: 705 QGRVEFLE 712
Q +E LE
Sbjct: 6254 Q-NLEILE 6260
Score = 160 bits (406), Expect = 6e-39
Identities = 256/1157 (22%), Positives = 432/1157 (37%), Gaps = 180/1157 (15%)
Query: 242 DKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVN 301
++ KV T+ I++ P K+ W K R + + DV +G+K L I N
Sbjct: 10922 EQHIKVGDTLRLSAIIK-GVPFPKVTWKKED---RDAPTKARIDVTPVGSK--LEIRNAA 10975
Query: 302 MNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMKPVKVTE-RQTAVFEIRLSKKEP 356
D GIYSL+V G K +S ++ VLD+P G + ++V+E R+ + + L+ KEP
Sbjct: 10976 HEDGGIYSLTVENPAGSKTVSVKVLVLDKP----GPPRDLEVSEIRKDSCY---LTWKEP 11028
Query: 357 ---------NFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGE---FSAEAG 404
N+V ++R D S T K A+ + G F A
Sbjct: 11029 LDDGGSVITNYV-------VERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 11081
Query: 405 NLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKK---DGQLLMHG 461
N + PIK + L + ++ +V+L W K DG + G
Sbjct: 11082 NQYGRGPFVETPKPIKALDPL---HPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITG 11138
Query: 462 TKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYY-------------STAIVT 508
EG + + + E V +Q G + +T +
Sbjct: 11139 YLVEYQEEGTQDWIKFKTV---TNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIE 11195
Query: 509 VEERLATVKSGM-----SDVHAATGSPAELCVVLNDEKV-EGVWLKDGKEITDLPGMQIV 562
+E+L + + G+ ++ V W DG EI +
Sbjct: 11196 CQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE 11255
Query: 563 KQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVF-------IADPPTIDPSVLEALAAH 615
L + G+Y +V + PPT ++L+ H
Sbjct: 11256 TDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEH 11315
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDS 675
T + P P + + + + ++ + G + L I + +
Sbjct: 11316 M-------TISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCE 11368
Query: 676 GLILLKLKNDHG-----SATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGG 730
+ ++ +N G +T T+ P PP G+ +++ + + W PK +GG
Sbjct: 11369 YVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPP-GKPVVTDITENAATVSWTLPKSDGG 11427
Query: 731 RPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL-E 789
P+T + +ERR V K W+++ + F + EG Y+FR+ A N G+S P
Sbjct: 11428 SPITGYYMERREVTGK-WVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 11486
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
++ + A PI+PPG P++ D ++E + W P DGG+P+LGY+VE +K G+ W
Sbjct: 11487 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWN 11546
Query: 850 PVNKDP-IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQD 908
+NKD I+ V GL+E EY FR+ A N G G+P + SV+AKD + PP + D
Sbjct: 11547 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 11606
Query: 909 LHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ D + R A ++ R E W+K G ++ R
Sbjct: 11607 VTCRDVITVRVGQTIRILAR--------VKGRPEPDITWTK------------EGKVLVR 11646
Query: 969 QKYFFRIRAVN--EAGVGEPVELDKGVRAMPPPAAPKFDLSARLKS---------HMVVR 1017
+K I+ + E + E V D G K+ +SA+ S +++ R
Sbjct: 11647 EKRVDLIQDLPRVELQIKEAVRADHG----------KYIISAKNSSGHAQGSAIVNVLDR 11696
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT---------KSKNHSQFLINSTKR- 1067
G + + W+ G IT K S + TKR
Sbjct: 11697 PGPCQNLKVTNVTKENCTISWENP--LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRL 11754
Query: 1068 -------SDSGVYRILLQNEFG-----EARYDI-HVRVADFPRPPTNLRLFEEVPNTVTL 1114
++ +R+ +N+ G E + I + D P P NL + ++ V L
Sbjct: 11755 IKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYL 11814
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAE-RVFSNKYTVTGLLPGRKYYFRVVARN 1173
W Y + +R + W + + Y V + + Y FRV +N
Sbjct: 11815 KWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKN 11874
Query: 1174 EIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPH---TVLRGQDC 1230
E G+S+ + + + ++ K+ +Q KP V LK TV G
Sbjct: 11875 EGGESDWVKTEE--VVVKEDLQ------KP------------VLDLKLSGVLTVKAGDTI 11914
Query: 1231 TMTCAFLGNPRPTV--TLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVE 1288
+ G P P V T K ++T + + ++ + + D G Y V
Sbjct: 11915 RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTAT 11974
Query: 1289 NELGKDRSSCTLTVYDK 1305
N G + T+ V DK
Sbjct: 11975 NTAGSFVAYATVNVLDK 11991
Score = 160 bits (406), Expect = 6e-39
Identities = 157/655 (23%), Positives = 275/655 (41%), Gaps = 61/655 (9%)
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDR-----PKPPQGRVEFLELSG 715
++ ++T + ++ + + ++ N +G SV+ + P PP G E +++
Sbjct: 20716 EECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITK 20774
Query: 716 SCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFR 775
+ + + W P +GG ++ + +E+R W K+ + + T + E YQ+R
Sbjct: 20775 NSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYR 20834
Query: 776 ILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVL 834
+ AVN+ G E E + A +PI+PPG ++ ++ D TK ++T+ W+ P DGG+ V
Sbjct: 20835 VCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 20894
Query: 835 GYIVERRKKGSNLWVPVN-KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSS 893
GY+VE R+ W V+ K ++ T+ V L Y FRV AVN AG G+P +
Sbjct: 20895 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 20954
Query: 894 VVAKDPVKPPGLVQD--LHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCT 951
V AKD ++ P + D L S + + + P +G PP +D K
Sbjct: 20955 VQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWR---KDEKNLGSDA 21011
Query: 952 KIPISGT----CYTVGGLIERQ--KYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFD 1005
+ I T T+ + KY I E GVGEP V+ + PAA +
Sbjct: 21012 RYSIENTDSSSLLTIPQVTRNDTGKYILTI----ENGVGEPKSSTVSVKVLDTPAACQ-- 21065
Query: 1006 LSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLIN 1063
+L+ V R L GSP + + +K + ++ + + F +
Sbjct: 21066 ---KLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI 21122
Query: 1064 STKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
+R+L +NE G V+ A+ P P +L + + +V L+W P
Sbjct: 21123 DLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWT-KP 21181
Query: 1121 DVQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGD 1177
D DG + Y++ ++ TW A + + V+ L FRV A+NE G
Sbjct: 21182 DF--DGGSVITEYVVERKGKGEQTWSHAGISK-TCEIEVSQLKEQSVLEFRVFAKNEKGL 21238
Query: 1178 SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT---PLKPHTVLRGQDCTMTC 1234
S+P+ + P K+ P P TV G + +
Sbjct: 21239 SDPVT------------------IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLEL 21280
Query: 1235 AFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVEN 1289
+ G P+P+++ K + + + ++ T TL I + G Y+V+++N
Sbjct: 21281 PYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN 21335
Score = 154 bits (389), Expect = 5e-37
Identities = 157/664 (23%), Positives = 267/664 (40%), Gaps = 60/664 (9%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+ ++KP+ VTA E F V + P + W +S + IK S K S K H L L
Sbjct: 2750 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKS-VEIKPSDKHRLVSERKVHKLML 2807
Query: 128 EPLTSDDSDNYKCIASNDHADA-IYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
+ ++ D+ Y + A ++ +L +T+ + ++ P+ K
Sbjct: 2808 QNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKNIE-----------VPETKTASFE 2856
Query: 187 NEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVE---------------- 230
E + S K E E +G L +L M E
Sbjct: 2857 CEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSA 2916
Query: 231 ---VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
V I I L+D + T+ F+ + + + K W+K ++ S K ++
Sbjct: 2917 TLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYK--WLKNGVEIK---STDKCQMR 2971
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+ L I NV+ DA Y+ G +A L V ++F +K +KV E++ A+F
Sbjct: 2972 TKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMF 3031
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E +S+ + W + +EL+ D+ I + ++ H L I R+SD+G+++ AG V
Sbjct: 3032 ECEVSEPDITVQWMKDDQELQITDR--IKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNV 3089
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A+L ++ ++ S K V+V E+ RA +E E+ DV W KDG + +
Sbjct: 3090 STAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3149
Query: 468 H--EGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ E + + I + + SD GEYT VA ++ Y A V + V
Sbjct: 3150 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNA-----PEPPQVLQELQPVTV 3204
Query: 526 ATGSPAELCVVLNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
+G PA C V++ + W K+ + ++ + + G + L+ PE YT
Sbjct: 3205 QSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYT 3264
Query: 585 FRAKG----TESEASVFIADPPTIDPSVLEALAAHAITVKV-------GHTAHIKVPFRG 633
AK + AS+ + P + P + AI + G A + G
Sbjct: 3265 CEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG 3324
Query: 634 KPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
L KV+WY ++ M + ED L I+ ED G N G ++T
Sbjct: 3325 TDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTA 3383
Query: 694 HLSV 697
+LS+
Sbjct: 3384 NLSL 3387
Score = 152 bits (385), Expect = 2e-36
Identities = 151/601 (25%), Positives = 256/601 (42%), Gaps = 58/601 (9%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+ P ID L+ I ++ G + + VP +G+P P+V W K E+ + + +
Sbjct: 16633 EAPDID---LDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSS 16689
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
L + N R DSG L L+N G+ +A + + VLD P PP ++ E++ V
Sbjct: 16690 FTS--LVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVN-LKVTEITKDSVS 16746
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTN-----KVEEGKAYQF 774
+ W+ P +GG + +IVE+R +KS+ + VTN N +++EG +Y F
Sbjct: 16747 ITWEPPLLDGGSKIKNYIVEKREATRKSYAAV------VTNCHKNSWKIDQLQEGCSYYF 16800
Query: 775 RILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPV 833
R+ A N G+ P +T + + +PPG + V DVT+ +V+++W P DGG+ +
Sbjct: 16801 RVTAENEYGIGLPAQTADPIKVAEVPQPPGKIT---VDDVTRNSVSLSWTKPEHDGGSKI 16857
Query: 834 LGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSS 893
+ YIVE + K S W + ++ + + L + EY FRV+AVN+ G P +
Sbjct: 16858 IQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP 16915
Query: 894 VVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKI 953
+VAKD V P V+ S S L P G P +D + T+I
Sbjct: 16916 IVAKDLVIEPD-VKPAFSSYSVQVGQDLKIEVPISGRPKPTITW---TKDGLPLKQTTRI 16971
Query: 954 PISGTC-YTVGGLIERQK---YFFRIRAVNEAGVG----EPVELDKGVRAMPPPAAPKFD 1005
++ + T + E K + I N G E V LDK PP KFD
Sbjct: 16972 NVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK---PDPPKGPVKFD 17028
Query: 1006 ----LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
S L + + G G + I QK T + ++ + +
Sbjct: 17029 DVSAESITLSWNPPLYTG----------GCQITNYIVQKRDTTTTVWDVVSATVARTTLK 17078
Query: 1062 INSTKRSDSGVYRILLQNEFGEA-RYDIHVRVADF----PRPPTNLRLFEEVPNTVTLTW 1116
+ K +RI +N +G++ + VA + P PP +++ + W
Sbjct: 17079 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 17138
Query: 1117 NHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGRKYYFRVVARNEI 1175
+ + Y + +++ ++ W + + ++ L G +Y FRV A N +
Sbjct: 17139 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIV 17198
Query: 1176 G 1176
G
Sbjct: 17199 G 17199
Score = 151 bits (381), Expect = 5e-36
Identities = 228/1018 (22%), Positives = 388/1018 (38%), Gaps = 103/1018 (10%)
Query: 224 EMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQY---- 279
EM + V+ + I LE E +D + I + + +I KG P + +
Sbjct: 20950 EMNEPVQAKDI-----LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDE 21004
Query: 280 ----SLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGD-----KRMSAELTVLDEPLKF 330
S +Y ++ + +L I V ND G Y L++ + K + + VLD P
Sbjct: 21005 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 21064
Query: 331 LGEMKPVKVTERQTAVFE-----IRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHT 385
+ VK R T I N+V +++ D + T S ++H
Sbjct: 21065 --QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYV-------IEKRDATKRTWSV--VSHK 21113
Query: 386 LKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSK 445
+L D E + ++ + ++ I P + +K V R + T
Sbjct: 21114 CSSTSFKLIDLSEKTPFFFRVLAENEIGIGE-PCETTEPVKAAEVPAPIRDLSMKDSTKT 21172
Query: 446 DVTLRWKK---DGQLLMHGTKYSMNHEGKRAELI----------IEDAQLSDGG--EYTV 490
V L W K DG ++ T+Y + +GK + IE +QL + E+ V
Sbjct: 21173 SVILSWTKPDFDGGSVI--TEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRV 21230
Query: 491 VAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT-----GSPAELCVVLNDEKVEGV 545
A + ++ + +TV+E + T + +SD+ A G L + + +
Sbjct: 21231 FAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI 21290
Query: 546 -WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIA----D 600
WLKDG + + ++ K L + EH GKYT +V I
Sbjct: 21291 SWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLG 21350
Query: 601 PPT--IDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME- 657
PP+ P + + A ++ + VP ++T Y T + M
Sbjct: 21351 PPSKPKGPIRFDEIKADSVILS------WDVP-EDNGGGEITCYSIEKRETSQTNWKMVC 21403
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDR-----PKPPQGRVEFLE 712
+ + N V++ ++ +N +G + + ++ + P PP G+
Sbjct: 21404 SSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GKPVIYN 21462
Query: 713 LSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAY 772
++ + + W AP +GG VT F VE++ W K+ + + EG Y
Sbjct: 21463 VTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDY 21522
Query: 773 QFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA 831
QFR+ A NS G+S P + + A +P++PPG P DVT+E +T+ WN P +DGG+
Sbjct: 21523 QFRVYAENSAGLSSPSDPSKFTLAVSPVDPPG---TPDYIDVTRETITLKWNPPLRDGGS 21579
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGP-GQPSVP 890
++GY +E+R +G+ WV N + + TV GL YEFR+IA N G PS
Sbjct: 21580 KIVGYSIEKR-QGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQS 21638
Query: 891 SSSVVAKDPVKPPGLVQDLHVSDS--SNSSISLAWREPAEGDP-PSGYILEMRAEDTKEW 947
S ++ +D PP + D S SL + +G P P + E K
Sbjct: 21639 SGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM 21698
Query: 948 SKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLS 1007
+ + T V + + + A N +G + E+ V+ P +
Sbjct: 21699 NMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK-AEIKVKVQDTPGKVVGPIRFT 21757
Query: 1008 ARLKSHMV------VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE-TITKSKNHSQF 1060
M + G A H + W + + T K N +++
Sbjct: 21758 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEY 21817
Query: 1061 LINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
+ + GV R L + I V D P P + N++TLTW
Sbjct: 21818 QFRVSAVNKFGVGRPL---DSDPVVAQIQYTVPDAPGIPEPSNI---TGNSITLTWARPE 21871
Query: 1121 DVQEDGEAHYIIMKRDASTATWYTAAER--VFSNKYTVTGLLPGRKYYFRVVARNEIG 1176
YI+ +R+ + W + + ++ VTGL G +Y F V+A N G
Sbjct: 21872 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 21929
Score = 147 bits (371), Expect = 7e-35
Identities = 156/631 (24%), Positives = 257/631 (40%), Gaps = 77/631 (12%)
Query: 702 KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNF 761
KP RV + + + V + W P+D GG VT +++E + V + W K K+ +
Sbjct: 23730 KPQNPRVT--DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREY 23787
Query: 762 STNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGFASQPQVTD--VTKEAV 818
+ + +G Y+FR+LA N+ G +P E V +E P + + + ++
Sbjct: 23788 TLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGG 23847
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN--------KDPIQGTKCTVDGLLEDT 870
I P + P+ + E + + + K+ +G T D +LE
Sbjct: 23848 VIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLE-- 23905
Query: 871 EYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE-- 928
NK G + +V V P P G L D S+ ++WR PA+
Sbjct: 23906 ---------NKCG--KKAVYIKVRVIGSPNSPEG---PLEYDDIQVRSVRVSWRPPADDG 23951
Query: 929 GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE 988
G GYILE R W + GT V GL E +Y FR+ A N+ G+ +P++
Sbjct: 23952 GADILGYILERREVPKAAWYTIDS-RVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLK 24010
Query: 989 LDKGVRAMPP--PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPT 1045
++ V P P P + L V ++ +L S S P D + G
Sbjct: 24011 SEEPVTPKTPLNPPEPPSNPPEVLD---VTKSSVSL------SWSRPKDDGGSRVTGYYI 24061
Query: 1046 KGRETIT-KSKNHSQFLINSTKRSDSGV-------YRILLQNEFGEARYD------IHVR 1091
+ +ET T K H++ I +T + +G+ +RI+ QN+ G + +
Sbjct: 24062 ERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 24121
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA-HYIIMKRDASTATWYTA-AERV 1149
D P P L + ++VTL W P+ E Y + R + + W + ER+
Sbjct: 24122 PFDKPSQPGELEILSISKDSVTLQWE-KPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 24180
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
++T+ GLL +Y FRV A NE G S P + + KL E
Sbjct: 24181 KDKQFTIGGLLEATEYEFRVFAENETGLSRP----------RRTAMSIKTKLTSGE---- 24226
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
AP +K T G+ ++C +G P P + Y+ + + K+ +S T
Sbjct: 24227 --APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT 24284
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
L + T +D G Y+ + NE+G+ +S L
Sbjct: 24285 LTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24315
Score = 146 bits (368), Expect = 1e-34
Identities = 152/685 (22%), Positives = 274/685 (40%), Gaps = 60/685 (8%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+F + VT PE +A F + A ++ W + I IK S K + K+H+L +
Sbjct: 5182 DFAVPLKDVTVPERRQARFECVLTREA--NVIWSKGPDI-IKSSDKFDIIADGKKHILVI 5238
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTVSLL------------VTEGQEKMDFKKMLKKRAP 175
DD Y A V+ + V EG+ ++ ++
Sbjct: 5239 NDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMH 5298
Query: 176 PAPKKKQKKVANEKEML-EILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAI 234
K K+ + +L K K + ++V ++ D + ++KE+ +++ +
Sbjct: 5299 VVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLD----DISQIKAQVKELSSTAQLKVL 5354
Query: 235 R----ILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
L DK + C + KD VK W K E + KY +K G
Sbjct: 5355 EADPYFTVKLHDKTAVEKDEITLKCEVS-KDVPVK--WFKDGEEI---VPSPKYSIKADG 5408
Query: 291 TKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIR 350
+ +L I ++ D G Y G + A +TV +K + V+V +TA FEI
Sbjct: 5409 LRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIE 5468
Query: 351 LSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKA 410
LS+ + + WK G+ L EI EDG H L + + +L +GE S +A N A
Sbjct: 5469 LSEPDVHGQWKLKGQPLTASPDCEII--EDGKKHILILHNCQLGMTGEVSFQAANAKSAA 5526
Query: 411 QLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEG 470
L + +P+ F++ L +V+V E+ A ECE++ + T RW K Q + ++ + +G
Sbjct: 5527 NLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDG 5586
Query: 471 KRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSP 530
+ ++I+ A D +Y A + +++ + +E + + DV A
Sbjct: 5587 TKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKFLTPLKDVTAKEKES 5640
Query: 531 AELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
A V L+ + + W K+ + + + + +G H + F + + + A G
Sbjct: 5641 AVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGM 5700
Query: 591 ESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTE 650
SEA + + + DP L + K ++ P V W+KDG E+
Sbjct: 5701 SSEAKLTVLEG---DPYFTGKLQDYTGVEKDEVILQCEISKADAP---VKWFKDGKEIKP 5754
Query: 651 EERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP---KPPQGR 707
+ ++ + +L + ++ D G + D G+ + L + DR P
Sbjct: 5755 SKNAVIKADGKKRMLILKKALKSDIG----QYTCDCGTDKTSGKLDIEDREIKLVRPLHS 5810
Query: 708 VEFL---------ELSGSCVHMKWK 723
VE + E+S +H WK
Sbjct: 5811 VEVMETETARFETEISEDDIHANWK 5835
Score = 143 bits (361), Expect = 1e-33
Identities = 192/826 (23%), Positives = 330/826 (39%), Gaps = 134/826 (16%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA-KIFYDSINKEHVL 125
P+ V P+PV EG+ A FR RV G +P ++W + K ++ YD I H L
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGI---HYL 1851
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPK------ 179
+ S D+ K A N + V L E Q++ DF+ +L++ P P+
Sbjct: 1852 DIVDCKSYDTGEVKVTAENPEGVIEHKVKL---EIQQREDFRSVLRRAPEPRPEFHVHEP 1908
Query: 180 -------------------------KKQKKVANEK---EMLEILSKVPKKDFEKVCMEYG 211
K+ +++ +EK E E+ SK ++ E
Sbjct: 1909 GKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAIT 1968
Query: 212 FTDFRGLLR--KLKEMKKKVEVEAIRILKPLEDKETK----------------------- 246
+ + + +E+ +K + E + K L ++E K
Sbjct: 1969 AVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPS 2028
Query: 247 VDTTVVFDCIME---------------LKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGT 291
++ +F+ I + P+ + W K ++I+ S Y
Sbjct: 2029 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNG--VKIERSDRIYWYWPEDN 2086
Query: 292 KYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPL-KFLGEMKPVKVTERQT-A 345
LVI +V D+ + G+ A L V + L F E++ V E+ T A
Sbjct: 2087 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2146
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSA---E 402
FE S+ W +G E+ DKY + D H L I SD+ ++S E
Sbjct: 2147 TFECETSEPFVKVKWYKDGMEVHEGDKYRM--HSDRKVHFLSILTIDTSDAEDYSCVLVE 2204
Query: 403 AGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGT 462
N+ A+L ++ ++FV L+++ V E LEC ++ +++ +W + L
Sbjct: 2205 DENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNG 2264
Query: 463 KYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSD 522
KY++ R L ++D D GEY+ V DG T T + ++ R + G+SD
Sbjct: 2265 KYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKT----TCKLKMKPRPIAILQGLSD 2318
Query: 523 VHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGK 582
G +L V ++ E VEGVW+KDG+E+ + IV H L+ M E G
Sbjct: 2319 QKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGN 2378
Query: 583 YTFR----AKGTESEASVFIAD--PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPL 636
Y+F T SV+ D P D +V+E K + VP +
Sbjct: 2379 YSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEG-------TKAVLECKVSVP----DV 2427
Query: 637 PKVTWYKDGMEVTEEERV-SMERGEDQALLTISNCVREDSG---LILLKLKNDHGSATAT 692
V WY + ++ ++RV ++ +G Q L+ I+ D G LI+ +++ + +
Sbjct: 2428 TSVKWYLNDEQIKPDDRVQAIVKGTKQRLV-INRTHASDEGPYKLIVGRVETNCNLSVEK 2486
Query: 693 LHL--SVLDRPKPPQGRVEF-LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
+ + + D V F +ELS S + + W KD +P +++ +E K +
Sbjct: 2487 IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNF-KDKEIKPSSKYKIEAHGKIYKLTV 2545
Query: 750 --KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEV 793
+ + +GK T ++ + GK L V +S PL + V
Sbjct: 2546 LNMMKDDEGKYTFYAGENMTSGK------LTVAGGAISKPLTDQTV 2585
Score = 143 bits (360), Expect = 1e-33
Identities = 157/639 (24%), Positives = 271/639 (42%), Gaps = 54/639 (8%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P GR E + ++ + V +KWK P +GG +T +IVE++ + W+K + T
Sbjct: 18297 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18356
Query: 761 FSTNKVEEGKAYQFRILAVNSEG-VSDPLETE-EVFAGNPIEPPGFASQPQVTDVTKEAV 818
F+ + + E + Y+FR++A N+ G S+P ++ + A + I+ P + P+ DV
Sbjct: 18357 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA 18416
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLED---TEYEFR 875
T+ G P+ + K G L + I+ T +++D T+
Sbjct: 18417 GETFVLEADIRGKPIPDVVWS--KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 18474
Query: 876 VIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPS 933
++ ++ G G S+P + V P P G L V+ + LAW P + G S
Sbjct: 18475 ILKLSNVG-GTKSIPITVKVLDRPGPPEG---PLKVTGVTAEKCYLAWNPPLQDGGANIS 18530
Query: 934 GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV 993
YI+E R W++ + + Y V L+ +Y FR+ AVN+ G+GEP+E
Sbjct: 18531 HYIIEKRETSRLSWTQVST-EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT 18589
Query: 994 RAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKG 1047
P PP+ P ++SA K MVV + G+ I +K D +
Sbjct: 18590 ACNPYKPPGPPSTP--EVSAITKDSMVVTWARPV----DDGGTEIEGYILEKRDKEGVRW 18643
Query: 1048 RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADF---PRPPTN 1101
+ K+ + + S +R+ +N G + + R D P PP+N
Sbjct: 18644 TKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSN 18703
Query: 1102 LRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAER--VFSNKYTVT 1157
++ + ++V+L W S + + G Y++ ++A+ W T + ++TVT
Sbjct: 18704 PKVTDTSRSSVSLAW--SKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVT 18761
Query: 1158 GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT 1217
L +Y FR+ A N G EP + ++ +++I+ +L +K V
Sbjct: 18762 KLKENTEYNFRICAINSEGVGEPATLPGS-VVAQERIEPPEIELDADLRK--------VV 18812
Query: 1218 PLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTL 1277
L+ LR + G P P V K + +T ++ TS LVI T
Sbjct: 18813 VLRASATLR-----LFVTIKGRPEPEVKWEKAEGILTDRAQI--EVTSSFTMLVIDNVTR 18865
Query: 1278 KDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
DSG Y++ +EN G + + V D V +I E
Sbjct: 18866 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIRE 18904
Score = 141 bits (356), Expect = 4e-33
Identities = 163/756 (21%), Positives = 295/756 (39%), Gaps = 74/756 (9%)
Query: 581 GKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVT 640
GKYT + S AS+ + P + +T K VP P
Sbjct: 19948 GKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVT-KESAVLSWDVPENDGGAPVKN 20006
Query: 641 WYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG---SATATLHLSV 697
++ + E +++ VS+ ++ ++N + +N+ G A + +
Sbjct: 20007 YHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI 20066
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
++P PP+ ++ +S V + W P+ +GG + ++VE G+K+W+K K
Sbjct: 20067 TEKPSPPE-KLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA--K 20123
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGFASQ--PQVTDVT 814
T+ + + E Y FR+ A N G+SDP E V +EPP + P T
Sbjct: 20124 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYV 20183
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE- 873
+ + + P G P+ + R VP+ T+ T + L + +
Sbjct: 20184 RAGSNLKVDIPIS--GKPLPKVTLSRDG------VPLKATMRFNTEITAENLTINLKESV 20235
Query: 874 ------FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA 927
+ + A N +G + + + VV P P G V +SD + S++L W P
Sbjct: 20236 TADAGRYEITAANSSGTTKAFI--NIVVLDRPGPPTGPVV---ISDITEESVTLKWEPPK 20290
Query: 928 E--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
G + YIL R T W++ + ++ T V L ++Y FRI+A N G+ +
Sbjct: 20291 YDGGSQVTNYILLKRETSTAVWTEVSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISD 20349
Query: 986 PVELDKGVRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDV 1036
++ +P PP+ P R + H V G + + +
Sbjct: 20350 HIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSI 20409
Query: 1037 IWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH---VRVA 1093
+WQK + + ++ + F + + +R+ +N G + V
Sbjct: 20410 LWQK------ANKLVIRT---THFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAI 20460
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSN 1152
D PP N+R+ + N+V+L+W YI+ +RD W A+ V
Sbjct: 20461 DACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTET 20520
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHA 1212
++ ++GL +Y FRV ARN +G I + S + P D
Sbjct: 20521 QFIISGLTQNSQYEFRVFARNAVGS----------------ISNPSEVVGPITCIDSYGG 20564
Query: 1213 PRFVTPLKPHTVLR---GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
P PL+ V++ G + G P PT+ YK D + N+ +T+ + +
Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20624
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
++I +SG Y + + N +G ++ + + DK
Sbjct: 20625 ILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20660
Score = 139 bits (349), Expect = 2e-32
Identities = 190/815 (23%), Positives = 305/815 (37%), Gaps = 84/815 (10%)
Query: 528 GSPAELCVVLNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
G P L ++ V W K G + G Q+ + L+ P+ + GKY+
Sbjct: 12316 GCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG-QVDLVDTMAFLVIPNSTRDDSGKYSLT 12374
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
E +VF+ P + L +T H + P +VT Y +
Sbjct: 12375 LVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSW--APPENDGGSQVTHYI--V 12430
Query: 647 EVTEEERVSMERGEDQALLT---ISNCVREDSGLILLKLKNDHGSATAT------LHLSV 697
E E +R + + T ++N V + + N++G T L
Sbjct: 12431 EKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12490
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKS--WIKIGEVD 755
L P PP+ ++E E++ + + W P +GG + +I R + + W + V
Sbjct: 12491 LSEPDPPR-KLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVV- 12548
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVT 814
K + ++EGK Y+FR+ A N+ GVS P E E V+ A + PP Q+T
Sbjct: 12549 -KDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQIT--I 12605
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEF 874
K + A P + + ++ + V+K D +D+ Y +
Sbjct: 12606 KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY-Y 12664
Query: 875 RVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPP 932
+ A N +G + + A P +PP +SD + SL+W P E G
Sbjct: 12665 SLTAENSSGTDTQKIKVVVMDAPGPPQPP-----FDISDIDADACSLSWHIPLEDGGSNI 12719
Query: 933 SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG 992
+ YI+E +W +C VG LI Q+Y FR+RA N G+ EP+ K
Sbjct: 12720 TNYIVEKCDVSRGDWVTALASVTKTSC-RVGKLIPGQEYIFRVRAENRFGISEPLTSPKM 12778
Query: 993 VRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT 1052
V P F + + K+ V + CI A+ PD G P G
Sbjct: 12779 VAQFP------FGVPSEPKNARVTKVNKD-CIFVAWDR---PD---SDGGSPIIGYLIER 12825
Query: 1053 KSKNH------SQFLINSTKRSDSGV-------YRILLQNEFGEA---RYDIHVRVADFP 1096
K +N + L+ ST+ +G+ +RI N+ G + + +V
Sbjct: 12826 KERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPV 12885
Query: 1097 RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWY---TAAERVFSNK 1153
PP + + +TV+L W Y + W TA ++ +
Sbjct: 12886 DPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEE 12945
Query: 1154 YTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ---DLSAKLKPYEKKDWR 1210
YT TGL +Y FR +AR + S P + D I + + DLS +K
Sbjct: 12946 YTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL----- 13000
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
TV G + + G P PTV+ K + +CTL
Sbjct: 13001 ------------TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTL 13048
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+ + KDSGDY++ EN G ++ L V DK
Sbjct: 13049 ELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 13083
Score = 137 bits (346), Expect = 5e-32
Identities = 219/998 (21%), Positives = 382/998 (38%), Gaps = 131/998 (13%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P K+ W K + I + K V + T LVI N +D+G YSL++ G+K +
Sbjct: 12329 PAPKVTWRK----VGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAV 12384
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITV 377
+ VLD P + ++K VT+ V + V + ++ + D K TV
Sbjct: 12385 FVNVRVLDTPGP-VSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTV 12443
Query: 378 SEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRAC 437
+ + + + + + F A N T P+ L + R
Sbjct: 12444 TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE---PDPPRKL 12500
Query: 438 LECELTSKDVTLRW---KKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQ 494
E+T TL W +DG + G S E + A+ E + + D V ++
Sbjct: 12501 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD-LSLVVTGLK 12559
Query: 495 DGDPTEYYSTA--------------IVTVEERL----------ATVKSGMS---DVHAAT 527
+G ++ A + +E+L T+K+G + H
Sbjct: 12560 EGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAH-VY 12618
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA 587
G P C W K E+ + + K + LI + + G Y+ A
Sbjct: 12619 GKPHPTC----------KWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTA 12668
Query: 588 K---GTESE---ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW 641
+ GT+++ V A P P + + A A ++ + HI + G + +
Sbjct: 12669 ENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL----SWHIPLEDGGSNI--TNY 12722
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG-SATATLHLSVLDR 700
+ +V+ + V+ + + + + ++ +N G S T V
Sbjct: 12723 IVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQF 12782
Query: 701 P-----KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVD 755
P +P RV +++ C+ + W P +GG P+ +++ER+ W+K +
Sbjct: 12783 PFGVPSEPKNARV--TKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTL 12840
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVT 814
+ T + + EG Y FRI A+N G S P + TE V A P++PPG +P+V DVT
Sbjct: 12841 VRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPG---KPEVIDVT 12897
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLLEDTEY 872
K V++ W P DGG+ ++GY VE K + WV N P I + T GL E +Y
Sbjct: 12898 KSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQY 12957
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSI------------- 919
+FR IA PS PS V PP + DL V+ S ++
Sbjct: 12958 QFRAIARTAVNISPPSEPSDPVTILAENVPPRI--DLSVAMKSLLTVKAGTNVCLDATVF 13015
Query: 920 -----SLAWR------EPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+++W+ +PAEG + R T E + T
Sbjct: 13016 GKPMPTVSWKKDGTLLKPAEGIK----MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 13071
Query: 969 QKYFFRIRAVNEAGVGEPVELDK--GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHA 1026
+ +++ +++ G V+++K RAM P D + + +++V + T+ A
Sbjct: 13072 KSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWA 13131
Query: 1027 AFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
S + P + + E + + + QF I + + G + + + Y
Sbjct: 13132 QVSATVP---------ITSCSVEKLIEGHEY-QFRICAENKYGVG-DPVFTEPAIAKNPY 13180
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA 1146
D R PP + ++ +T++W D Y++ KR+ W
Sbjct: 13181 DPPGRC----DPPVISNITKD---HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVN 13233
Query: 1147 ER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ + TGL G +Y FRV A N+ G +P D+
Sbjct: 13234 RKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDA 13271
Score = 137 bits (344), Expect = 9e-32
Identities = 160/649 (24%), Positives = 257/649 (39%), Gaps = 75/649 (11%)
Query: 690 TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
T L ++ +DRP P+ + + + V++KW+ P +GG P + VERR G W
Sbjct: 11785 TPILAINPIDRPGEPEN-LHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWE 11843
Query: 750 KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQ 809
++ + K T++ ++ E + Y+FR+ N G SD ++TEEV ++ P +
Sbjct: 11844 RVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLS 11903
Query: 810 VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLE 868
K TI A + P + + ++ V D +K ++
Sbjct: 11904 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11963
Query: 869 DTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE 928
++ V A N AG V ++V D PG V++L + D S+ ++ W P +
Sbjct: 11964 SDGGKYVVTATNTAGS---FVAYATVNVLDK---PGPVRNLKIVDVSSDRCTVCWDPPED 12017
Query: 929 --GDPPSGYILEMRAEDTKEWSKCTKIPIS-GTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
G YILE WS + ++ GT TV LIE +Y FR+RA N+ G G
Sbjct: 12018 DGGCEIQNYILEKCETKRMVWSTYSATVLTPGT--TVTRLIEGNEYIFRVRAENKIGTGP 12075
Query: 986 PVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPT 1045
P E + P A K+D R V + +PP + DG +
Sbjct: 12076 PTE------SKPVIAKTKYDKPGRPDPPEVTKVSKE---EMTVVWNPP-----EYDGGKS 12121
Query: 1046 KGRETITKSKNHSQFLINSTKRS--------------DSGVYRILLQNEFGEARYDIHVR 1091
+ K + HS + K + +R+ +NE G + R
Sbjct: 12122 ITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR 12181
Query: 1092 VA------DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKR----DAS 1138
+ P PPTN R+ + +++TL W DG A Y++ R DAS
Sbjct: 12182 PVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPV---YDGGAPIIGYVVEMRPKIADAS 12238
Query: 1139 TATWY---TAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ 1195
+ AA ++ ++TVT L ++Y FRV A+N++G P
Sbjct: 12239 PDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP--------------A 12284
Query: 1196 DLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA 1255
+L +KP E + + K V G + G P P VT K ++
Sbjct: 12285 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 12344
Query: 1256 NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
K + + LVIP T DSG YS+ + N G+ + V D
Sbjct: 12345 R-KGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLD 12392
Score = 135 bits (341), Expect = 2e-31
Identities = 152/639 (23%), Positives = 252/639 (39%), Gaps = 77/639 (12%)
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKA 771
+++ + + +KW PKDNG P+ + +E+R V W ++ + + + + EG
Sbjct: 8608 DVTSNSMLVKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 8666
Query: 772 YQFRILAVNSEG---VSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQD 828
Y FR+ A N+ G S P + + A +PI PPG P+VTD + + + W P +
Sbjct: 8667 YVFRVCAENAAGPGKFSPPSDPKT--AHDPISPPG-PPIPRVTDTSSTTIELEWEPPAFN 8723
Query: 829 GGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPS 888
GG ++GY V+++ G+N W + I+ + TV + E +Y+ RV AVN AG G P
Sbjct: 8724 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPG 8783
Query: 889 VPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWS 948
VA +P +PP + D+ V R PA ++ R TK W+
Sbjct: 8784 ETQPVTVA-EPQEPPAVELDVSVKGGIQIMAGKTLRIPA--------VVTGRPVPTKVWT 8834
Query: 949 KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP-------AA 1001
K G L + + + +E + + + D G + AA
Sbjct: 8835 K-----------EEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAA 8883
Query: 1002 PK---FDLSARLKSHMVVRAGTALCIHAAFSGSPPPD---------VIWQKDGVPTKGRE 1049
+ FD+ + V +C+ + S P D +I +KD R+
Sbjct: 8884 ARVEVFDVPGPVLDLKPVVTNRKMCL---LNWSDPEDDGGSEITGFIIERKDAKMHTWRQ 8940
Query: 1050 TITKSKNHSQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRL 1104
I ++ I +R++ +N+FG E + V P P L
Sbjct: 8941 PIETERSKCD--ITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTY 8998
Query: 1105 FEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGR 1163
E +T+TL W YII KR + +R+ + + V L +
Sbjct: 8999 TERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQ 9058
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHT 1223
Y FRV A NEIG+SEP S ++ +D + KL+ + D
Sbjct: 9059 MYEFRVKAVNEIGESEP--SLPLNVVIQDDEVPPTIKLRLSVRGD------------TIK 9104
Query: 1224 VLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS------KFWYNSTSGVCTLVIPTCTL 1277
V G+ + G P P + K + I + K + + L IP
Sbjct: 9105 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 9164
Query: 1278 KDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
+D G Y+V N LG + + VYD+ ++T+
Sbjct: 9165 EDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9203
Score = 130 bits (328), Expect = 6e-30
Identities = 143/631 (22%), Positives = 251/631 (39%), Gaps = 64/631 (10%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P G ++++++ + +KW P +GG + + +E+R G + W++ D
Sbjct: 21549 PVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQ-GNERWVRCNFTDVSECQ 21607
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE--VFAGNPIEPPGFASQPQVTD--VTKE 816
++ + G Y+FRI+A N+ G P + + PP P+ D + K
Sbjct: 21608 YTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKS 21667
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
++ A Q P + + + + + + + D + T V D + V
Sbjct: 21668 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTV 21726
Query: 877 IAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGD--PPSG 934
A N +G + + V +D P +V + ++ + ++L W P P +
Sbjct: 21727 EAKNASGSAKAEI---KVKVQDT--PGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITH 21781
Query: 935 YILEMRAEDTKEWS----KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELD 990
YI+E R W+ KC YT LI +Y FR+ AVN+ GVG P++ D
Sbjct: 21782 YIIEKRETSRLAWALIEDKC-----EAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSD 21836
Query: 991 KGVRAMP--PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKG 1047
V + P AP + + + + + GS I ++ + T+
Sbjct: 21837 PVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR---PESDGGSEIQQYILERREKKSTRW 21893
Query: 1048 RETITKSK-NHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV------ADFPRPPT 1100
+ I+K + ++F + + + ++ +N G R+ + P PPT
Sbjct: 21894 VKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPT 21953
Query: 1101 NLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTA-AERVFSNKYTVT 1157
+++ + TV+L W S V + G YII A W+ AE +YTVT
Sbjct: 21954 VVKVTDTSKTTVSLEW--SKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVT 22011
Query: 1158 GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ----DLSAKLKPYEKKDWRHAP 1213
L G +Y FRV A N G + + T + D++ D+ A K
Sbjct: 22012 DLQAGEEYKFRVSAINGAGKGDSCEVTGT-IKAVDRLTAPELDIDANFK----------- 22059
Query: 1214 RFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIP 1273
+ H V G + A+ G P PT K D N++ + ++T TL +
Sbjct: 22060 ------QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI--HTTDSFSTLTVE 22111
Query: 1274 TCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
C D+G Y++ VEN G + T+ V D
Sbjct: 22112 NCNRNDAGKYTLTVENNSGSKSITFTVKVLD 22142
Score = 130 bits (327), Expect = 8e-30
Identities = 192/809 (23%), Positives = 309/809 (38%), Gaps = 115/809 (14%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
W K EI D + + + L+ ++ GKYT + + S F+
Sbjct: 16671 WGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDT 16728
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW----YKDGMEVTEEERVSMERGED 661
PS L IT K +TW G ++ E
Sbjct: 16729 PSPPVNLKVTEIT---------------KDSVSITWEPPLLDGGSKIKNYIVEKREATRK 16773
Query: 662 QALLTISNCVRED----------SGLILLKLKNDHG---SATATLHLSVLDRPKPPQGRV 708
++NC + S + +N++G A + V + P+PP G++
Sbjct: 16774 SYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKI 16832
Query: 709 EFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEE 768
+++ + V + W P+ +GG + Q+IVE +A + W + V K + +
Sbjct: 16833 TVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARV--KSLQAVITNLTQ 16890
Query: 769 GKAYQFRILAVNSEGVSDP--LETEEVFAGNPIEP---PGFASQP-QVTDVTKEAV---- 818
G+ Y FR++AVN +G SDP L V IEP P F+S QV K V
Sbjct: 16891 GEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG 16950
Query: 819 ----TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEF 874
TITW T+DG P+ K+ + + V D + T ++ +D ++
Sbjct: 16951 RPKPTITW---TKDG-LPL--------KQTTRINVT---DSLDLTTLSIKETHKDDGGQY 16995
Query: 875 RVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPP 932
+ N G S+ ++ DP K P + D S SI+L+W P G
Sbjct: 16996 GITVANVVGQKTASIEIVTLDKPDPPKGP-----VKFDDVSAESITLSWNPPLYTGGCQI 17050
Query: 933 SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG 992
+ YI++ R T W ++ T V L +Y FRI A N G +E D
Sbjct: 17051 TNYIVQKRDTTTTVWD-VVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI 17109
Query: 993 VRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGV 1043
V P PP P ++ ++ H V G + I ++W
Sbjct: 17110 VAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW----- 17164
Query: 1044 PTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQN--EFGEARYDIHVRVADFP-RPPT 1100
TK +TI + +QF + + +R+ +N G+A + VA P PP
Sbjct: 17165 -TKVNKTII---HDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG 17220
Query: 1101 NLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAA-ERVFSNKYTVT 1157
N +TL W + V + G YI+ KRD W A+ V ++TV+
Sbjct: 17221 TPEPIMVKRNEITLQW--TKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVS 17278
Query: 1158 GLLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
GL ++Y FRV+A+N G S+P DS + KD+++ P D P+F
Sbjct: 17279 GLTEDQRYEFRVIAKNAAGAISKPSDSTGP-ITAKDEVE------LPRISMD----PKFR 17327
Query: 1217 TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
+ V G+ + G P PT+ +GD I +++ +T L++
Sbjct: 17328 DTI---VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAI 17384
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
D G Y + N G + V D+
Sbjct: 17385 RIDGGQYILRASNVAGSKSFPVNVKVLDR 17413
Score = 130 bits (326), Expect = 1e-29
Identities = 117/443 (26%), Positives = 200/443 (45%), Gaps = 28/443 (6%)
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K+ V I KPL D+ VF+C E+ +P+ K W++ + L + ++ +
Sbjct: 2568 KLTVAGGAISKPLTDQTVAESQEAVFEC--EVANPDSKGEWLRDGKHLPLTNNIRS---E 2622
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G K L+I+ ++D G Y+ V + SA+L V E +K +K + VTE Q AVF
Sbjct: 2623 SDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKV--EAVKIKKTLKNLTVTETQDAVF 2680
Query: 348 EIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+ L+ V W NG L+ ++KY I+V G ++L+IK+ + D + G L
Sbjct: 2681 TVELTHPNVKGVQWIKNGVVLESNEKYAISVK--GTIYSLRIKNCAIVDESVYGFRLGRL 2738
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
A+L ++ + K + K+V E + E ++ V ++W + K+ +
Sbjct: 2739 GASARLHVETV--KIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRL 2796
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
E K +L++++ SD GEYT V Q E + V E L K+ M ++
Sbjct: 2797 VSERKVHKLMLQNISPSDAGEYTAVVGQ----LECKAKLFV---ETLHITKT-MKNIEVP 2848
Query: 527 TGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
A ++ V +WLK+G EI +IV QG +H+LI + E +YTF
Sbjct: 2849 ETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV 2908
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
+ A++ + P + S+L+ + A K T + V + G W K+G+
Sbjct: 2909 CGNDQVSATLTVT--PIMITSMLKDINAEE---KDTITFEVTVNYEG---ISYKWLKNGV 2960
Query: 647 EVTEEERVSMERGEDQALLTISN 669
E+ ++ M + L I N
Sbjct: 2961 EIKSTDKCQMRTKKLTHSLNIRN 2983
Score = 130 bits (326), Expect = 1e-29
Identities = 162/646 (25%), Positives = 269/646 (41%), Gaps = 69/646 (10%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P GR E + ++ + V ++WK P +GG +T +IVE++ + + W+K + T+
Sbjct: 16133 PCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTH 16192
Query: 761 FSTNKVEEGKAYQFRILAVNSEGV-SDPLE-TEEVFAGNPIEPPGFASQPQVTD--VTKE 816
F + E Y+FR++A N+ GV S+P E T + A + ++PP + P+ D V
Sbjct: 16193 FEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHA 16252
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
+ +A P + +I ++ + + + + D + D+
Sbjct: 16253 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG---NY 16309
Query: 877 IAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSG 934
I K G+ SV + V P P G V +S + +LAW+ P + G
Sbjct: 16310 ILKAKNVAGERSVTVNVKVLDRPGPPEGPVV---ISGVTAEKCTLAWKPPLQDGGSDIIN 16366
Query: 935 YILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVR 994
YI+E R W+ + +C V L+E +Y FRI AVN+ GVGEP+E + V
Sbjct: 16367 YIVERRETSRLVWTVVDANVQTLSC-KVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVA 16425
Query: 995 AMP--PPAAPKF-DLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI 1051
P P APK +++ K M+V A+ GS + +K + +E I
Sbjct: 16426 KNPFVVPDAPKAPEVTTVTKDSMIVVWERP----ASDGGSEILGYVLEK-----RDKEGI 16476
Query: 1052 TKSKNHSQFLINSTKRSDSGV-------YRILLQNEFG------EARYDIHVRVADFPRP 1098
++ H + LI + +G+ +R+ +N G + Y P P
Sbjct: 16477 RWTRCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGP 16535
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDG--EAHYIIMKRDASTATWYTAAERVFSNKYT- 1155
P N ++ + ++V L+W S + + G YI+ K D S W NK
Sbjct: 16536 PNNPKVIDITRSSVFLSW--SKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNI 16593
Query: 1156 -VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ----DLSAKLKPYEKKDWR 1210
V LL +Y FR+ A N+ G E D +I +++++ DL +L+
Sbjct: 16594 EVEKLLEKHEYNFRICAINKAGVGEHADVPGP-IIVEEKLEAPDIDLDLELRKIINIRAG 16652
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
+ R P+K G P P V K D I + + TS +L
Sbjct: 16653 GSLRLFVPIK-----------------GRPTPEVKWGKVDGEIRDAAII--DVTSSFTSL 16693
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
V+ DSG Y++ +EN G + T+ V D V +TE
Sbjct: 16694 VLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTE 16739
Score = 129 bits (324), Expect = 2e-29
Identities = 180/796 (22%), Positives = 290/796 (36%), Gaps = 82/796 (10%)
Query: 543 EGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPP 602
E W ++ E TD +QI K +L + GKY + + + S F+
Sbjct: 17750 EITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17807
Query: 603 TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQ 662
P + LA + G K + D E T + ++ +
Sbjct: 17808 LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK-NYVIDKRESTRKAYANVSSKCSK 17866
Query: 663 ALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ--GRVEFLELSGSCVHM 720
+ N + +N+ G + + +PP G+V ++S + +
Sbjct: 17867 TSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASL 17926
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W+ P+ +GG V ++VE + G + W + E KV N + G+ YQFR+ A N
Sbjct: 17927 MWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAE--SKVCNAVVTGLSSGQEYQFRVKAYN 17984
Query: 781 SEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA------PVL 834
+G SDP G P+ QP ++ + +N + G PV+
Sbjct: 17985 EKGKSDPR-----VLGVPVIAKDLTIQP--------SLKLPFNTYSIQAGEDLKIEIPVI 18031
Query: 835 GYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY-----------EFRVIAVNKAG 883
G R + + WV + Q T+ V+ T ++ V A N AG
Sbjct: 18032 G-----RPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG 18086
Query: 884 PGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRA 941
++ S +V + P P G V+ + S + ++W PA G S YI+E R
Sbjct: 18087 TATENL--SVIVLEKPGPPVGPVR---FDEVSADFVVISWEPPAYTGGCQISNYIVEKRD 18141
Query: 942 EDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMP---- 997
T W + ++ T + L +Y FRI A N G P++ + P
Sbjct: 18142 TTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP 18200
Query: 998 -PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT 1052
PP P ++ ++ H V G I ++W K T ++T
Sbjct: 18201 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLN-KTPIQDTKF 18259
Query: 1053 KSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTV 1112
K+ + L K S + I ++ E D PP N V
Sbjct: 18260 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFV-----ARDPCDPPGRPEAIVITRNNV 18314
Query: 1113 TLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVA 1171
TL W YI+ K+D W A+ V ++TV+GL+ ++Y FRV+A
Sbjct: 18315 TLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIA 18374
Query: 1172 RNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDC 1230
RN G+ SEP DS + +D+I +A L P K V G+
Sbjct: 18375 RNAAGNFSEPSDSSGA-ITARDEIDAPNASLDPKYK-------------DVIVVHAGETF 18420
Query: 1231 TMTCAFLGNPRPTVTLYKGDVNITAN-SKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVEN 1289
+ G P P V K + ++ ST TLV+ C D G Y + + N
Sbjct: 18421 VLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSN 18480
Query: 1290 ELGKDRSSCTLTVYDK 1305
G T+ V D+
Sbjct: 18481 VGGTKSIPITVKVLDR 18496
Score = 123 bits (309), Expect = 1e-27
Identities = 159/650 (24%), Positives = 271/650 (41%), Gaps = 64/650 (9%)
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
L + L P P+ R+ + E + S + + WK P+ NGG P+ +I+E+R K + ++
Sbjct: 8982 LAVDPLGPPTSPE-RLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 9040
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVT- 811
+ T+F ++E + Y+FR+ AVN G S+P V + PP + V
Sbjct: 9041 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG 9100
Query: 812 DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP-----VNKDPIQG----TKCT 862
D K + P G P+ +E K + + P + K+ + T+ +
Sbjct: 9101 DTIKVKAGEPVHIPADVTGLPMPK--IEWSKNETVIEKPTDALQITKEEVSRSEAKTELS 9158
Query: 863 VDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ + + + + V A N+ G +V V D PP ++L V+D S L
Sbjct: 9159 IPKAVREDKGTYTVTASNRLGSVFRNV---HVEVYDRPSPP---RNLAVTDIKAESCYLT 9212
Query: 923 WREPAE--GDPPSGYILEMRAEDTK--EWSKCTKIPISGTCYTVGGLIERQKYFFRIRAV 978
W P + G + Y+++ R K EW + T + Y + LI +Y FR+RAV
Sbjct: 9213 WDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKR-YGIWKLIPNGQYEFRVRAV 9271
Query: 979 NEAGVGEPVELDKGVRAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
N+ G+ + + DK V P PP PK + AR K M+V L +G P
Sbjct: 9272 NKYGISDECKSDKVVIQDPYRLPGPPGKPK--VLARTKGSMLVSWTPPLD-----NGGSP 9324
Query: 1034 PDVIW---QKDGVP---TKGRETITK-SKNHSQFLINSTKRSDSGVYRILLQNEFG---- 1082
W +++G P R ITK +F + +R + N G
Sbjct: 9325 ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPP 9384
Query: 1083 EARYDIHVRVADF--PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDAS 1138
D V P PP+ + ++ ++++L W P ++ G YI+ ++
Sbjct: 9385 SEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWK--PPAKDGGSPIKGYIVEMQEEG 9442
Query: 1139 TATWYTAAER---VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ 1195
T W E + + + V L RKY FRV A NE G+SEP D+ T I IQ
Sbjct: 9443 TTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDT--TGEIPATDIQ 9500
Query: 1196 DLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTC-AFLGNPRPTVTLYKGDVNIT 1254
+ +D + + ++ V++G+ + F G + + D+
Sbjct: 9501 EEPEVFIDIGAQDCLVC-KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 9559
Query: 1255 ANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
A + NS+ ++IP C +G YS+ +N+ G+ ++C + V D
Sbjct: 9560 AQLETAENSS----VIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMD 9605
Score = 122 bits (307), Expect = 2e-27
Identities = 148/640 (23%), Positives = 248/640 (38%), Gaps = 83/640 (12%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
+RP PP G++ ++++ + V + W+ P+ +GG + +IVE + G W V KV
Sbjct: 15742 ERPLPP-GKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATV--KV 15798
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGF----------ASQ 807
T + + +G+ Y FR+ A N +G+SDP + V A + + PP F A +
Sbjct: 15799 TEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGE 15858
Query: 808 PQVTDVT---KEAVTITW---NAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
DV + +TW N P + E + S L +
Sbjct: 15859 DLKVDVPFIGRPTPAVTWHKDNVPLKQ----TTRVNAESTENNSLLTIK----------- 15903
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
D ED + + V N AG ++ + +V+ D PP + + + + SI+L
Sbjct: 15904 --DACREDVGH-YVVKLTNSAGE---AIETLNVIVLDKPGPP--TGPVKMDEVTADSITL 15955
Query: 922 AWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVN 979
+W P G + YI+E R T W + ++ T L +Y FRI A N
Sbjct: 15956 SWGPPKYDGGSSINNYIVEKRDTSTTTW-QIVSATVARTTIKACRLKTGCEYQFRIAAEN 16014
Query: 980 EAGVGEPVELDKGVRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSG 1030
G + + V P PP P LS+R ++ + + G + I
Sbjct: 16015 RYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLER 16074
Query: 1031 SPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYD--I 1088
++W K + I ++K F + +R+ +N G +
Sbjct: 16075 KERNSILWVK-----LNKTPIPQTK----FKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 16125
Query: 1089 HVRVADFP-RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA- 1146
VA P PP N+VTL W YI+ K++ W A+
Sbjct: 16126 ECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASF 16185
Query: 1147 ERVFSNKYTVTGLLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYE 1205
+ + VTGL+ +Y FRV+ARN G SEP +S + +D++ + P
Sbjct: 16186 TNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA-ITARDEVDPPRISMDPKY 16244
Query: 1206 KKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTS 1265
K V G+ + G P PT+ KGD ++ ++ ST
Sbjct: 16245 KDTI-------------VVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16291
Query: 1266 GVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+L + DSG+Y + +N G+ + + V D+
Sbjct: 16292 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDR 16331
Score = 122 bits (306), Expect = 2e-27
Identities = 200/934 (21%), Positives = 332/934 (35%), Gaps = 131/934 (14%)
Query: 441 ELTSKDVTLRWKK---DGQLLMHGTKYSMNHEGKRA-------------ELIIEDAQLSD 484
+ T K +L W K DG L + G G A + ++ D Q +
Sbjct: 14378 DTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKE 14437
Query: 485 GGEYTVVAMQD---GDPTEYYSTAIVTVE-----------ERLATVKSGMSD--VHAATG 528
+ + A+ D G+P IV E R V++G+S G
Sbjct: 14438 KYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKG 14497
Query: 529 SPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAK 588
PA E W KD + + ++ + + LI P GK+ +
Sbjct: 14498 RPAP----------EVTWTKDNINLKNRANIENTESFTL--LIIPECNRYDTGKFVMTIE 14545
Query: 589 GTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEV 648
+ S F+ P + L IT K T H +P G +
Sbjct: 14546 NPAGKKSGFVNVRVLDTPGPVLNLRPTDIT-KDSVTLHWDLPL----------IDGGSRI 14594
Query: 649 TE---EERVSMERGEDQALLTISNCVREDSGL-------ILLKLKNDHG---SATATLHL 695
T E+R + + A C + +GL + +N++G T +
Sbjct: 14595 TNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPV 14654
Query: 696 SVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVD 755
+ P PP + ++++ S V + W PK +GG +T +++E + G W I V
Sbjct: 14655 KASEAPSPPDS-LNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVK 14713
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQP--QVTDV 813
G + EG+ Y F+++AVNS G S P E+ V P + Q +
Sbjct: 14714 G--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14771
Query: 814 TKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCT----VDGLLED 869
K I P P + + KKG + + + T + ++ +
Sbjct: 14772 AKAGDNIKVEIPVLGRPKPTVTW-----KKGDQILKQTQRVNFETTATSTILNINECVRS 14826
Query: 870 TEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE- 928
+ + A N G + ++ D PP + + S+ ++ +W P
Sbjct: 14827 DSGPYPLTARNIVGEVGDVI---TIQVHDIPGPP--TGPIKFDEVSSDFVTFSWDPPEND 14881
Query: 929 -GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPV 987
G P S Y++EMR D+ W + I T Y L +Y FR++A N GVG +
Sbjct: 14882 GGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRYGVGPGI 14940
Query: 988 ELDKGVRAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG 1042
V P PP P+ ++A K M + H S P + + +
Sbjct: 14941 TSACIVANYPFKVPGPPGTPQ--VTAVTKDSMTISW------HEPLSDGGSPILGYHVER 14992
Query: 1043 VPTKGRETITKSKNHSQFLINSTKRSDSGV---YRILLQNEFGEARYD------IHVRVA 1093
G T SK I + G+ +R++ +N G+++ + +
Sbjct: 14993 KERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPI 15052
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSN 1152
D P P L + +TVTL W YI+ KRD W A + N
Sbjct: 15053 DPPGKPVPLNITR---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILEN 15109
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHA 1212
++TV+GL Y FRV+A+N G P + +D ++ + K+K K
Sbjct: 15110 EFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVE--APKIKVDVK------ 15161
Query: 1213 PRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLV 1271
K +L+ G+ + G P PT+ K + +K LV
Sbjct: 15162 ------FKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLV 15215
Query: 1272 IPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
T +DSG Y++ N G + + V D+
Sbjct: 15216 NKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDR 15249
Score = 121 bits (303), Expect = 5e-27
Identities = 146/660 (22%), Positives = 265/660 (40%), Gaps = 56/660 (8%)
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLE 128
F ++ Q V A E D + W ++ G+ + E K S K H L +
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKD-GMEVHEGDKYRMHSDRKVHFLSIL 2188
Query: 129 PLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANE 188
+ + D+++Y C+ D + + T + L+ EG ++F K L+ P + +
Sbjct: 2189 TIDTSDAEDYSCVLVED--ENVKTTAKLIVEG-AVVEFVKELQDIEVPESYSGELECIVS 2245
Query: 189 KEMLEILSKVPKKDFE-KVCMEYGFTDFRG--------------------LLRKLKEMKK 227
E +E K D E K +Y T RG + K K
Sbjct: 2246 PENIE--GKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K++ I IL+ L D++ V + + L+ +V+ +W+K + ++ + K
Sbjct: 2304 KMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE--SVEGVWMKDGQEVQPSDRVHIVIDK 2361
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
Q +ML+I ++ DAG YS ++ +S V + + +K V V E AV
Sbjct: 2362 Q---SHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVL 2418
Query: 348 EIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
E ++S + V W N +++K DD+ + V G L I SD G + G +
Sbjct: 2419 ECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK--GTKQRLVINRTHASDEGPYKLIVGRV 2476
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
L++++ IK + L+++ E E EL+ + + W + + +KY +
Sbjct: 2477 ETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKI 2534
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
GK +L + + D G+YT A E ++ +TV + ++D A
Sbjct: 2535 EAHGKIYKLTVLNMMKDDEGKYTFYA------GENMTSGKLTVAG--GAISKPLTDQTVA 2586
Query: 527 TGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A C V N + +G WL+DGK + ++ G +LI + + G+YT+
Sbjct: 2587 ESQEAVFECEVANPDS-KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTY 2645
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+ +++ A + + +V +TV A V + V W K+G
Sbjct: 2646 KVATSKTSAKLKV-------EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNG 2698
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
+ + E+ ++ L I NC D + +L A+A LH+ + K P+
Sbjct: 2699 VVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL--GRLGASARLHVETVKIIKKPK 2756
Score = 121 bits (303), Expect = 5e-27
Identities = 150/654 (22%), Positives = 261/654 (39%), Gaps = 83/654 (12%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P G+ E ++++ S V + W PK +GG + + VE + W++ ++
Sbjct: 12884 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12943
Query: 761 --FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE---VFAGNPIEPPGFASQPQVTDVTK 815
++ +EE YQFR +A + +S P E + + A N + + K
Sbjct: 12944 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVK 13003
Query: 816 EAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN--KDPIQGTKCTVD--GLLEDTE 871
+ +A P + + KK L P K +Q CT++ +
Sbjct: 13004 AGTNVCLDATVFGKPMPTVSW-----KKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 13058
Query: 872 YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--G 929
++ + A N +G S+ + + PG + ++ + L+W P E G
Sbjct: 13059 GDYTITAENSSGS------KSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGG 13112
Query: 930 DPPSGYILEMRAEDTKEWSKCTK-IPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE 988
+ YI++ R W++ + +PI T +V LIE +Y FRI A N+ GVG+PV
Sbjct: 13113 SEITNYIVDKRETSRPNWAQVSATVPI--TSCSVEKLIEGHEYQFRICAENKYGVGDPVF 13170
Query: 989 LDKGVRAMPPPAAPKFD---LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPT 1045
+ + P + D +S K HM V S PP D G P
Sbjct: 13171 TEPAIAKNPYDPPGRCDPPVISNITKDHMTV------------SWKPPAD----DGGSPI 13214
Query: 1046 KG-----RET--ITKSKNHSQFLINSTKRSDSGV-------YRILLQNEFG-----EARY 1086
G RET + +K + + +I T ++ +G+ +R+ N+ G +A
Sbjct: 13215 TGYLLEKRETQAVNWTKVNRKPIIERTLKA-TGLQEGTEYEFRVTAINKAGPGKPSDASK 13273
Query: 1087 DIHVRVADFPR-PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTA 1145
+ R +P PP ++++ ++V+L+W Y++ + A + W
Sbjct: 13274 AAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRC 13333
Query: 1146 --AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203
+ + ++ VTGL+ +Y FRV A N+IG S+P D D K +D+ + P
Sbjct: 13334 NLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPD-----KHYPKDIL--IPP 13386
Query: 1204 YEKKDWRHAPRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
+ D L+ +LR G + G P P +T K +VN+
Sbjct: 13387 EGELD--------ADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK 13438
Query: 1263 STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
ST L D+G Y + +EN GK + + V D V ++ E
Sbjct: 13439 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKE 13492
Score = 121 bits (303), Expect = 5e-27
Identities = 140/627 (22%), Positives = 244/627 (38%), Gaps = 83/627 (13%)
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
V + W P +GG +T+++VER+ G+++W G K ++++E +FR+
Sbjct: 21174 VILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGI--SKTCEIEVSQLKEQSVLEFRVF 21231
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTIT------WNAPTQDGGA 831
A N +G+SDP+ + I P + ++D+ VT+ P +
Sbjct: 21232 AKNEKGLSDPVTIGPITVKELIITP----EVDLSDIPGAQVTVRIGHNVHLELPYKGKPK 21287
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
P + ++ + + +V +K + T ++ ++ ++ VI N + +VP
Sbjct: 21288 PSISWLKDGLPLKESEFVRFSKTENKIT-LSIKNAKKEHGGKYTVILDNAVC--RIAVPI 21344
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSK 949
+ + P KP G ++ + S+ L+W P + G + Y +E R W K
Sbjct: 21345 TVITLGPPSKPKGPIR---FDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW-K 21400
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEP-----VELDKGVRAMPPPAAPKF 1004
++ T + V L++ +Y FR+RA N GV +P + R PP P
Sbjct: 21401 MVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVI 21460
Query: 1005 DLSARLKSHMVVRAGTALCIHA-AFSGSPPP-----------DVIWQKDGV-PTKGRETI 1051
+ V G +L A + G ++WQK P GRE
Sbjct: 21461 --------YNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGRE-- 21510
Query: 1052 TKSKNHSQFLINSTKRSDSGVYRILLQNEFG------EARYDIHVRVADFPRPPTNLRLF 1105
+ +R+ +N G +++ + V D P P + +
Sbjct: 21511 --------YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVT 21562
Query: 1106 EEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGR 1163
E T+TL WN P +++ G Y I KR + V +YTVTGL PG
Sbjct: 21563 RE---TITLKWN--PPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGD 21617
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHT 1223
+Y FR++ARN +G P ++ +D+ + P + P + L
Sbjct: 21618 RYEFRIIARNAVGTISPPSQSSGIIMTRDE------NVPPIVE----FGPEYFDGL---I 21664
Query: 1224 VLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDY 1283
+ G+ + G P P VT +K V I G +L + T G Y
Sbjct: 21665 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21724
Query: 1284 SVLVENELGKDRSSCTLTVYDKDDKSV 1310
+V +N G ++ + V D K V
Sbjct: 21725 TVEAKNASGSAKAEIKVKVQDTPGKVV 21751
Score = 120 bits (302), Expect = 7e-27
Identities = 163/681 (23%), Positives = 272/681 (39%), Gaps = 74/681 (10%)
Query: 361 KFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIK 420
+ N EL R + + +G + +IK A + GE A +++ K L + +
Sbjct: 11547 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 11606
Query: 421 FVS-NLKNVRVKERSRACLECE-LTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIE 478
++ VRV + R + D+T W K+G++L+ + + + R EL I+
Sbjct: 11607 VTCRDVITVRVGQTIRILARVKGRPEPDIT--WTKEGKVLVREKRVDLIQDLPRVELQIK 11664
Query: 479 DAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLN 538
+A +D G+Y + A + +AIV V +R G T E C +
Sbjct: 11665 EAVRADHGKYIISAKNSSGHAQ--GSAIVNVLDR-----PGPCQNLKVTNVTKENCTISW 11717
Query: 539 DEKVEGVWLKDGKEITDL---------PGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKG 589
+ ++ G EIT+ G IV +LI ++ +E Y FR
Sbjct: 11718 ENPLD----NGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNE--YYFRV-C 11770
Query: 590 TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYK---DGM 646
E++ V PTI+ LA + I + G ++ + +GK + W + DG
Sbjct: 11771 AENKVGV----GPTIETKT-PILAINPID-RPGEPENLHIADKGKTFVYLKWRRPDYDGG 11824
Query: 647 EVTEEERVSME-RGED-----------QALLTISNCVREDSGLILLKLKNDHGSATATLH 694
V +G D + + CV ++ KN+ G +
Sbjct: 11825 SPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKT 11884
Query: 695 LSVL---DRPKPPQGRVEFLELSGSCV-----HMKWKAPKDNGGRPVTQFIVERRA--VG 744
V+ D KP V L+LSG ++ +A P + ++ A +
Sbjct: 11885 EEVVVKEDLQKP----VLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11940
Query: 745 KKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGF 804
+ +KI + + FS K + ++ + A N+ G T N ++ PG
Sbjct: 11941 RSPRVKI-DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATV-----NVLDKPGP 11994
Query: 805 ASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI-QGTKCTV 863
++ DV+ + T+ W+ P DGG + YI+E+ + +W + + GT TV
Sbjct: 11995 VRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGT--TV 12052
Query: 864 DGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAW 923
L+E EY FRV A NK G G P+ S V+AK PG V+ S +++ W
Sbjct: 12053 TRLIEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVW 12111
Query: 924 REPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEA 981
P G +GY LE + + + W K I V L+ +Y FR++A NE
Sbjct: 12112 NPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEI 12171
Query: 982 GVGEPVELDKGVRAMPPPAAP 1002
G+GEP + V A P P
Sbjct: 12172 GIGEPSLPSRPVVAKDPIEPP 12192
Score = 117 bits (294), Expect = 6e-26
Identities = 148/628 (23%), Positives = 233/628 (37%), Gaps = 87/628 (13%)
Query: 713 LSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAY 772
+S S + WK P +GG + ++V+ K W ++ + +S + EGK Y
Sbjct: 13590 VSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRV--MKSLSLQYSAKDLTEGKEY 13646
Query: 773 QFRILAVNSEGVSDPLETEEVFAGNPIEPP-GFASQPQVTDVTKEAVTITWNAPTQDGGA 831
FR+ A N G P E V + + P P + + KE P + A
Sbjct: 13647 TFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPA 13706
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
P + + ++ V V + T D D ++ + N AG + ++ S
Sbjct: 13707 PSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAG-KYTITLKNVAGTKEGTI-S 13764
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSK 949
VV K P P G ++ + + +++L W P + G + YILE R +W
Sbjct: 13765 IKVVGK-PGIPTGPIK---FDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13820
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSAR 1009
C + T + V L E +Y FR+ A N+ GVGE G+++ P A FD+
Sbjct: 13821 CASA-VQKTTFRVTRLHEGMEYTFRVSAENKYGVGE------GLKSEPIVARHPFDVP-- 13871
Query: 1010 LKSHMVVRAGTALCIHAAFSGSPPPDVI----------W----QKDGVPTKGRETITKSK 1055
PPP+++ W + G P G K +
Sbjct: 13872 -------------------DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKER 13912
Query: 1056 NH-------------SQFLINSTKRSDSGVYRILLQNEFGEARYDIH---VRVADFPRPP 1099
N F + +R++ N G + + V D PP
Sbjct: 13913 NSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13972
Query: 1100 TNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAE-RVFSNKYTVTG 1158
+ N+VTL W YI+ KRD + +W A V +TVT
Sbjct: 13973 GKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTD 14032
Query: 1159 LLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT 1217
L+ G KY FR+ A+N G S P +S +T +I KD+ + + L P K
Sbjct: 14033 LVEGGKYEFRIRAKNTAGAISAPSESTET-IICKDEYEAPTIVLDPTIKDGL-------- 14083
Query: 1218 PLKPHTVLRGQDCTMTC-AFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
T+ G + + LG P P + K +I + ST L I T
Sbjct: 14084 -----TIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 14138
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYD 1304
KD+G+Y++ N G +TV D
Sbjct: 14139 RKDAGEYTITATNPFGTKVEHVKVTVLD 14166
Score = 109 bits (273), Expect = 2e-23
Identities = 145/639 (22%), Positives = 241/639 (37%), Gaps = 71/639 (11%)
Query: 695 LSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEV 754
++V +RP+ +E E++ + V + W PK +GG + +++E R +G + + K+
Sbjct: 10409 ITVPERPED----LEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTND 10464
Query: 755 DGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVT 814
+ ++ ++EG Y++R+ AVN G P F PI + P +
Sbjct: 10465 NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPS-----FCTKPITCKDELAPPTLHLDF 10519
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE- 873
++ +TI + G A L + K W D ++ + + E
Sbjct: 10520 RDKLTI------RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEK 10573
Query: 874 ----------FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAW 923
+ V+ N G + + V D PP V + + + + ++W
Sbjct: 10574 IKAKRSDSGKYCVVVENSTGSRKGFCQVNVV---DRPGPP--VGPVSFDEVTKDYMVISW 10628
Query: 924 REPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEA 981
+ P + G + YI+E + W T TC V L+E + Y FRI A N
Sbjct: 10629 KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTC-KVSKLLEGKDYIFRIHAENLY 10687
Query: 982 GVGEPVELD--KGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQ 1039
G+ +P+ D K P AP + + + G P + I +
Sbjct: 10688 GISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNK----PHDGGKPITNYILE 10743
Query: 1040 KDGVPTKGRETITKSKNH--SQFLINSTKRSDSGVYRILLQNEFG------EARYDIHVR 1091
K +K +TK H ++F + +R+ +NE G ++
Sbjct: 10744 KRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKD 10803
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTA---A 1146
P PP N + N+V LTW P + G YI+ + W A
Sbjct: 10804 PIAKPSPPVNPEAIDTTCNSVDLTWQ--PPRHDGGSKILGYIVEYQKVGDEEWRRANHTP 10861
Query: 1147 ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEK 1206
E KY VTGL G+ Y FRV+A N G+S+P + L+ KD+++ L
Sbjct: 10862 ESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLV-KDRLEPPELILD---- 10916
Query: 1207 KDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG 1266
+ + G ++ G P P VT K D + A +K + T
Sbjct: 10917 ---------ANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD--APTKARIDVTPV 10965
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
L I +D G YS+ VEN G S + V DK
Sbjct: 10966 GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 11004
Score = 107 bits (268), Expect = 6e-23
Identities = 144/617 (23%), Positives = 249/617 (40%), Gaps = 55/617 (8%)
Query: 217 GLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLR 276
G K K VE +R +K LE++ T V ++ K+ +V +W K +
Sbjct: 4890 GNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDV--VWRKDGKI-- 4945
Query: 277 IQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV---GDKRMSAELTVLDEPLKFLGE 333
+ G+ +G L I++ + DAG Y+++V + S+ + V++ +L
Sbjct: 4946 VVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWL-- 5003
Query: 334 MKPVK---VTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKD 390
+KP++ V + TA+F ++K PN W E+ + + + DG LKIK+
Sbjct: 5004 VKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKN 5063
Query: 391 ARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLR 450
A D E++ E A+LT+ ++ + +++V + E+ A + E++ D+ +
Sbjct: 5064 AMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQ 5123
Query: 451 WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVE 510
WK G+LL + EG + L + +L GE A+ +TAI+TV+
Sbjct: 5124 WKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQAL------NAITTAILTVK 5177
Query: 511 ERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHK 569
E + DV A CV+ + V +W K I I+ G H
Sbjct: 5178 EIELDFAVPLKDVTVPERRQARFECVLTREANV--IWSKGPDIIKSSDKFDIIADGKKHI 5235
Query: 570 LIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKV 629
L+ + EG YT +G ++ A +F+ S LE TVK G TA
Sbjct: 5236 LVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQ-----TVKEGETATFVC 5290
Query: 630 PFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA 689
+ + V W+K+ ++ V + L + +D I ++K
Sbjct: 5291 ELSHEKM-HVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVK----EL 5345
Query: 690 TATLHLSVLDRPK------PPQGRVEFLELSGSC-----VHMKWKAPKDNGGRPVTQFIV 738
++T L VL+ + VE E++ C V +KW +G V
Sbjct: 5346 SSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKW---FKDGEEIVPSPKY 5402
Query: 739 ERRAVGKKSWIKIGEVDGK-----VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEV 793
+A G + +KI + D K V + T+K + + R++ V PL EV
Sbjct: 5403 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEK-----PLYGVEV 5457
Query: 794 FAGNPIEPPGFASQPQV 810
F G S+P V
Sbjct: 5458 FVGETAHFEIELSEPDV 5474
Score = 107 bits (266), Expect = 1e-22
Identities = 168/748 (22%), Positives = 293/748 (39%), Gaps = 96/748 (12%)
Query: 232 EAIRILKPLEDKETKVDTTVVFDC-IMELKDPNVKMIWIK-GTEPLRIQYSLGKYDVKQM 289
EA I K ++D TK+ C I+ P++K W + G E ++ + KY +
Sbjct: 24226 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSR----KYKMSSD 24279
Query: 290 GTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
G + L + D G+Y+ VG+ S++L + P G P+K
Sbjct: 24280 GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGY--PLKEKYYGAV 24337
Query: 346 VFEIRL-----SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFS 400
+RL + P W F+G++L ++ + + + TH + R + +G++
Sbjct: 24338 GSTLRLHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYK 24396
Query: 401 AEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMH 460
+ N+ +D +++ K +E L + V + WK
Sbjct: 24397 VQLSNVFGTVDAILD-------VEIQDKPDKPTGPIVIEALLKNSAV-ISWKPPAD---D 24445
Query: 461 GTKYSMNH--------EGKRAELIIEDAQLS---------DGGEYTVVAMQD----GDPT 499
G + N+ EG +L+ ++ + G Y V+ Q+ DP
Sbjct: 24446 GGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPL 24505
Query: 500 EYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVL-------NDEKVEGVWLKDGKE 552
E S I+ + K G T + CVV K+ +L+ +E
Sbjct: 24506 EVSSVVII----KSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEK-RE 24560
Query: 553 ITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAK----GTESEASVFI------ADPP 602
+ + + + + +F +Y FR K G ESE S +D P
Sbjct: 24561 KKQNKWISVTTE-EIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVP 24619
Query: 603 TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEE---RVSMERG 659
P E L + V+ A + G P P V WY+ G E+ + R+ +G
Sbjct: 24620 IQAPHFKEEL--RNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKG 24677
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV-----LDRPKPPQGRVEFLELS 714
L+ I++ +D+ + ++ N GS + T L V + PK +G L
Sbjct: 24678 GYHQLI-IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALR 24736
Query: 715 GSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQF 774
G V +K P PV + + + ++ + N VE A +
Sbjct: 24737 GEVVSIK--IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFY 24794
Query: 775 RILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVL 834
+ A N G+ +T E+ + +PP +V+DV++++V +TW P DGG+ +
Sbjct: 24795 VVCAKNRFGIDQ--KTVELDVADVPDPPRGV---KVSDVSRDSVNLTWTEPASDGGSKIT 24849
Query: 835 GYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSV 894
YIVE+ + W+ V + + T+ TV L T Y+FRVIA NK G +PS PS
Sbjct: 24850 NYIVEKCATTAERWLRVGQ--ARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPT 24907
Query: 895 VAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ K+ K + D V ++ S++ A
Sbjct: 24908 ITKED-KTRAMNYDEEVDETREVSMTKA 24934
Score = 98.2 bits (243), Expect = 5e-20
Identities = 145/714 (20%), Positives = 274/714 (38%), Gaps = 108/714 (15%)
Query: 3 TIHSRQMLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPA 62
T+ + L VS EF TT V T K EE +S +V + +T P
Sbjct: 977 TVSTSCYLAVQVSEEFEKETTAV-----TEKFTTEEKRFVESRDVVMTDTSLTEEQAGPG 1031
Query: 63 GDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA--KIFYDSIN 120
+ P F+ KP EG VF +V GN KPH+ WK+ SG+P+ K+ Y+
Sbjct: 1032 EPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK-SGVPLTTGYRYKVSYNKQT 1090
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK 180
E L + +DD+ Y + N H + + SLL E+ D++ ++K + +
Sbjct: 1091 GECKLVISMTFADDAGEYTIVVRNKHGETSASASLL-----EEADYELLMKSQQEMLYQT 1145
Query: 181 KQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPL 240
+ E ++ E ++EK EY ++ ++KK+ + + + +
Sbjct: 1146 QVTAFVQEPKVGETAPGFVYSEYEK---EYE--------KEQALIRKKMAKDTVVVRTYV 1194
Query: 241 EDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNV 300
ED+E + + ++ +K I+Y + K ++++
Sbjct: 1195 EDQEFHISS---------FEERLIK----------EIEYRIIKTTLEEL----------- 1224
Query: 301 NMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKE-PNFV 359
+ + G ++V A + D +K ++ E F ++S P
Sbjct: 1225 -LEEDGEEKMAVDISESEAVESGFDS------RIKNYRILEGMGVTFHCKMSGYPLPKIA 1277
Query: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQLTID 415
W +GK +K ++Y++ +DG +L+I D G ++A A GN + +L ++
Sbjct: 1278 WYKDGKRIKHGERYQMDFLQDGRA-SLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Query: 416 -RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAE 474
P+ + + + R R+ ++ + + + M + S
Sbjct: 1337 PAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMS--------- 1387
Query: 475 LIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH--AATGSPAE 532
A++S G +++ D ++ ERL + V G A
Sbjct: 1388 ----PARMSPGRR-----LEETDESQL---------ERLYKPVFVLKPVSFKCLEGQTAR 1429
Query: 533 LCV-VLNDEKVEGVWLKDGKEIT-DLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
+ V+ E W DG++I D ++K+ LI P G++T A+
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489
Query: 591 ESEASVFI-----ADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+S+ + A + P +E L + +K G +KV G P P + W K+
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKN--VNIKEGSRLEMKVRATGNPNPDIVWLKNS 1547
Query: 646 MEVTEEE--RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
+ + ++ +E + +A L I + V +DS N G T ++V
Sbjct: 1548 DIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1601
Score = 95.9 bits (237), Expect = 2e-19
Identities = 152/639 (23%), Positives = 238/639 (37%), Gaps = 111/639 (17%)
Query: 430 VKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
VK + CL+ + K + T+ WKKDG LL M + L + D G+Y
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 13061
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCV-VLNDEKVEGVW- 546
T+ TA + + AT+K + D G PA + + + ++ W
Sbjct: 13062 TI-------------TAENSSGSKSATIKLKVLD---KPGPPASVKINKMYSDRAMLSWE 13105
Query: 547 --LKDG----------KEITDLPGMQIVKQG------AVHKLIFPSMGPEHEGKYTFRAK 588
L+DG K T P V +V KLI HE ++ A+
Sbjct: 13106 PPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLI-----EGHEYQFRICAE 13160
Query: 589 G---------TESEASVFIADPP-TIDPSVLEALAAHAITVKVGHTAHIK-VPFRGKPLP 637
TE + DPP DP V+ + +TV A P G L
Sbjct: 13161 NKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLE 13220
Query: 638 K-----VTWYKDGMEVTEEERVS----MERGEDQALLTISNCVREDSGLILLKLKNDHGS 688
K V W K + E + E E + +T N K G
Sbjct: 13221 KRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAIN-------------KAGPGK 13267
Query: 689 ATATLHLSVLDRPKPPQGRVEF---LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGK 745
+ + P+ P G F + + S V + W P +GG P+ ++VE +
Sbjct: 13268 PSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS 13327
Query: 746 KSWIKIGEVDG-KVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLET-EEVFAGNPIEPPG 803
+W++ + T F + E YQFR+ AVN G SDP + ++ + + + PP
Sbjct: 13328 DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPE 13387
Query: 804 --FASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
+ + T + + VT+ P + P + + K NL + D
Sbjct: 13388 GELDADLRKTLILRAGVTMRLYVPVKGRPPPKITW----SKPNVNLRDRIGLD------- 13436
Query: 862 TVDGLLEDTEYE--FRVIAVNKAGPGQPSVPSSSVVAKDP-------VKPPGLVQDLHVS 912
++ T+++ R VNK G+ + + K + PG ++ V
Sbjct: 13437 -----IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVK 13491
Query: 913 DSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQK 970
+ S S + W P G P Y+++ R + K WS T S T + V L E +
Sbjct: 13492 EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTT-ECSKTSFRVANLEEGKS 13550
Query: 971 YFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSAR 1009
YFFR+ A NE G+G+P E V+A P P DL R
Sbjct: 13551 YFFRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVR 13588
Score = 92.8 bits (229), Expect = 2e-18
Identities = 110/495 (22%), Positives = 193/495 (38%), Gaps = 34/495 (6%)
Query: 232 EAIRILKPLEDKETKV-DTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
+ I + L+D K DT F+C E +P VK+ W K + + KY +
Sbjct: 2126 QLITFTQELQDVVAKEKDTMATFEC--ETSEPFVKVKWYKDGMEV---HEGDKYRMHSDR 2180
Query: 291 TKYMLVISNVNMNDAGIYS-LSVGDKRM--SAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+ L I ++ +DA YS + V D+ + +A+L V ++F+ E++ ++V E +
Sbjct: 2181 KVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGEL 2240
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E +S + W N ELK + KY IT S G L +KD D GE+S
Sbjct: 2241 ECIVSPENIEGKWYHNDVELKSNGKYTIT-SRRG-RQNLTVKDVTKEDQGEYSFVIDGKK 2298
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
+L + PI + L + +V E LE +++ + V W KDGQ + + +
Sbjct: 2299 TTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIV 2358
Query: 468 HEGKRAELIIEDAQLSDGGEYT----VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
+ + L+IED D G Y+ + + YS ++T + DV
Sbjct: 2359 IDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVIT----------PLKDV 2408
Query: 524 HAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGK 582
+ G+ A L C V + W + ++I +Q + +G +L+ EG
Sbjct: 2409 NVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGP 2468
Query: 583 YTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWY 642
Y E+ ++ + ++ L T +++ G V W
Sbjct: 2469 YKLIVGRVETNCNLSVE-----KIKIIRGLRDLTCTETQNVVFEVELSHSG---IDVLWN 2520
Query: 643 KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPK 702
E+ + +E LT+ N +++D G + S T+ + +P
Sbjct: 2521 FKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAISKPL 2580
Query: 703 PPQGRVEFLELSGSC 717
Q E E C
Sbjct: 2581 TDQTVAESQEAVFEC 2595
Score = 88.2 bits (217), Expect = 5e-17
Identities = 139/589 (23%), Positives = 233/589 (39%), Gaps = 79/589 (13%)
Query: 65 SVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV 124
+ P K +P+ G A F +Q W + +G I ES K S +++
Sbjct: 4527 AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFK-AGREIYESDKCSIRS--SKYI 4583
Query: 125 LKLEPLTSD--DSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPA----- 177
LE L + D Y C ASN++ T +L VT + +K+L +R P
Sbjct: 4584 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV 4643
Query: 178 --------PKKKQKKVANEKEMLEILSK--VPKKDFEKVCMEYGFTDFRGLLRKLKEMKK 227
P++++ KV E + LE + K VP+ K E RK+ E K
Sbjct: 4644 LKSVLRKRPEEEEPKV--EPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK 4701
Query: 228 KVEVEA----------------IRILKP--LEDKETKVDTTVVFDCI---MELKDPNVKM 266
E++ ++ +KP +E + T + V + E K P +
Sbjct: 4702 VPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEA 4761
Query: 267 IWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMS-AELT--V 323
KG +K + K S + + S G+K A T +
Sbjct: 4762 AKPKGP-------------IKGVPKK---TPSPIEAERRKLRPGSGGEKPPDEAPFTYQL 4805
Query: 324 LDEPLKFLGEMKPVKVTERQ----TAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSE 379
PLKF+ E+K + +TE + +A+FE +S W +G ++ K+
Sbjct: 4806 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIA-- 4863
Query: 380 DGLTHTLKIKDARLSDSGEFSA--EAGN--LVQKAQLTIDRIPIKFVSNL-KNVRVKERS 434
DG L I D +LSD+GE++ GN A+L ++ +P++FV L + V V +
Sbjct: 4864 DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQ 4923
Query: 435 RACLECELTSKDVTLRWKKDGQLLMHGT-KYSMNHEGKRAELIIEDAQLSDGGEYTVVAM 493
L CEL +K+ + W+KDG++++ + G L I DA +D G YT V +
Sbjct: 4924 PLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYT-VTV 4981
Query: 494 QDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEI 553
++ + E S+ + VE + + D H A + + W K EI
Sbjct: 4982 ENANNLE-CSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEI 5040
Query: 554 TDLPG--MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIAD 600
P +I++ G L + PE +Y +G A + + +
Sbjct: 5041 PAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGE 5089
Score = 85.9 bits (211), Expect = 2e-16
Identities = 154/685 (22%), Positives = 262/685 (38%), Gaps = 91/685 (13%)
Query: 76 VTAPEGDKAVFRARVQGNAKPHISWK-RESGIPIKESAKIFYDSINKEHVLKLEPLTSDD 134
+ A E D F V IS+K ++G+ IK + K + H L + + D
Sbjct: 2932 INAEEKDTITFEVTVNYEG---ISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGD 2988
Query: 135 SDNYKCIASNDHADAIYTVSLLVTEGQEKM-DFKKMLKKRA--------PPAPKKKQK-- 183
+ +Y +A + A V E ++ + D K + KKRA P + K
Sbjct: 2989 AADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDD 3048
Query: 184 ---------KVANEKEMLEILSKVPK-KDFEKVCMEYG--------FTDFRGLLRKLKEM 225
K+ EK + +L + D K + G F + R + +++ +
Sbjct: 3049 QELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDV--RIRSI 3106
Query: 226 KKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYS-LGKY 284
KK+V+V +E + V+ E+ + +V W K + Q KY
Sbjct: 3107 KKEVQV--------IEKQRAVVE--------FEVNEDDVDAHWYKDGIEINFQVQERHKY 3150
Query: 285 DVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTV-LDEPLKFLGEMKPVKVTERQ 343
V++ + + IS +DAG Y+ G R S L V EP + L E++PV V +
Sbjct: 3151 VVERR--IHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGK 3208
Query: 344 TAVFEIRLS-KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAE 402
A F +S + +P W + L K + DG +TL + +A D+ ++ E
Sbjct: 3209 PARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL--HDGQEYTLLLIEAFPEDAAVYTCE 3266
Query: 403 AGN----LVQKAQLTIDR------------IPIKFVSNLKNVRVKERSRACLECELTSKD 446
A N A L+++ P ++ L++ E A +C ++ D
Sbjct: 3267 AKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTD 3326
Query: 447 VTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAI 506
+ + W + + + M +L I +A D G YT VA + STA
Sbjct: 3327 LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA--SNAVGQVSSTAN 3384
Query: 507 VTVEERLATVKSGMSDVHAATGSPA--ELCVVLNDEKVEGVWLKDGKEIT---DLPGMQI 561
+++E + +S DV + S A + + K+ +K + + ++ +
Sbjct: 3385 LSLEVQALDRQSSGKDVRESAKSQAVADSSFTKEESKISQKEIKSFQGSSYEYEVQVFES 3444
Query: 562 VKQGAVHKLI-FPSMGPEHEGKYTFRAKGTESE---ASVFIADPPTIDPSVLEALAAHAI 617
V Q ++H H + A+ TE A + P I L +
Sbjct: 3445 VSQSSIHTAASVQDTQLCHTASLSQIAESTELSKECAKESTGEAPKI------FLHLQDV 3498
Query: 618 TVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGL 677
TVK G TA + VTW +G ++ E ER+ + + LTI N D GL
Sbjct: 3499 TVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGL 3558
Query: 678 ILLKLKNDHGSATATLHLSVLDRPK 702
+ ND G T + LSV P+
Sbjct: 3559 YSCIVHNDCGERTTSAVLSVEGAPE 3583
Score = 85.9 bits (211), Expect = 2e-16
Identities = 147/715 (20%), Positives = 268/715 (37%), Gaps = 124/715 (17%)
Query: 72 KPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLT 131
KP+ +T EG+ A F G P ++W R+ + + SA+ + + ++ +
Sbjct: 26261 KPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQV-LSTSARHQVTTTKYKSTFEISSVQ 26319
Query: 132 SDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKR--------APPAPKKKQK 183
+ D NY + N +EG+++ +F ++K +PP K +
Sbjct: 26320 ASDEGNYSVVVEN-------------SEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEP 26366
Query: 184 KVANEKEMLEILS-KVPKKDFEKVCMEYGFTDFRGL-LRKLKEMKKKVEVEAIRILKPLE 241
+V + + + K P+ K T+ + K++ + + + LK
Sbjct: 26367 RVKSPEAVKSPKRVKSPEPSHPKAVSP---TETKPTPTEKVQHLPVSAPPKITQFLKAEA 26423
Query: 242 DKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVN 301
KE T VV ++ K+ + W K + L+ + ++ GT Y L I+N+
Sbjct: 26424 SKEIAKLTCVVESSVLRAKE----VTWYKDGKKLK-ENGHFQFHYSADGT-YELKINNLT 26477
Query: 302 MNDAGIYSLSVGDKRMSAE--LTVLDEPLKFLGEM------------------------- 334
+D G Y + + +++ L + + K + E
Sbjct: 26478 ESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP 26537
Query: 335 --------KPVKVTERQ--------TAVFEIRLS-KKEPNFVWKFNGKELKRDDKYEITV 377
KPV VT Q A F ++ + + P +W +GK + + KY++
Sbjct: 26538 KAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL-- 26595
Query: 378 SEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTIDRIP---IKFVSNLKNVRV 430
SED L+I SDSG ++ AG++ +LTI I + VS K +
Sbjct: 26596 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEI 26655
Query: 431 KERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTV 490
+ +A ++ E++ K + K + K ++ E + LI E+ + S
Sbjct: 26656 TPQKKAVVQEEISQKALRSEEIKMSEAKSQ-EKLALKEEASKV-LISEEVKKSAATSLEK 26713
Query: 491 VAMQDGDPTEYYSTAIVTVEERL-ATVKSGMSDVHAATGSPAELCVVLNDEKVEGV-WLK 548
+ + E T+ + E R A +K+ + + G L + N V W+
Sbjct: 26714 SIVHE----EITKTSQASEEVRTHAEIKAFSTQMSINEGQ--RLVLKANIAGATDVKWVL 26767
Query: 549 DGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTE---------------SE 593
+G E+T+ + G+ L EG T +K E S+
Sbjct: 26768 NGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSD 26827
Query: 594 ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEER 653
A FI+ P + + G G+P P++ W+K+ + ++
Sbjct: 26828 APAFISQP-------------RSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN 26874
Query: 654 VSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRV 708
VS+ R + L I N DSG +K KN G +AT L VL + P V
Sbjct: 26875 VSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREV 26929
Score = 83.6 bits (205), Expect = 1e-15
Identities = 80/296 (27%), Positives = 128/296 (43%), Gaps = 15/296 (5%)
Query: 417 IPIKFVSNLKNVRVKER----SRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKR 472
+P+KFV +K++ + E S A EC ++ W KDG + K+ +GK
Sbjct: 4808 VPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKD 4867
Query: 473 AELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAE 532
+L I D QLSD GEYT V ++ G+ + + +V E + VK+ +V G P
Sbjct: 4868 RKLHIIDVQLSDAGEYTCV-LRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 4926
Query: 533 LCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQ--GAVHKLIFPSMGPEHEGKYTFRAKGT 590
L LN E+ + VW KDGK + + PG +IV G + L G YT +
Sbjct: 4927 LSCELNKER-DVVWRKDGKIVVEKPG-RIVPGVIGLMRALTINDADDTDAGTYTVTVENA 4984
Query: 591 ES-EASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVT 649
+ E S + I +++ + VK TA K P + W+K E+
Sbjct: 4985 NNLECSSCVKVVEVIRDWLVKPIRDQ--HVKPKGTAIFACDI-AKDTPNIKWFKGYDEIP 5041
Query: 650 EE--ERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKP 703
E ++ + R + L I N + ED ++++ A TL ++ KP
Sbjct: 5042 AEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKP 5097
Score = 83.6 bits (205), Expect = 1e-15
Identities = 150/648 (23%), Positives = 250/648 (38%), Gaps = 101/648 (15%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
D+P P G +E L +S V ++W+ P+ +GG+ + + VE R G +W K + K
Sbjct: 24124 DKPSQP-GELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKD 24182
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-----EVFAGNPIEPPGFASQPQVTDV 813
F+ + E Y+FR+ A N G+S P T ++ +G E PG + ++ DV
Sbjct: 24183 KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSG---EAPGI--RKEMKDV 24237
Query: 814 TKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC---------TVD 864
T T+ G A L + R W K+ IQ K T+
Sbjct: 24238 T-----------TKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24286
Query: 865 GLLEDTEYE--FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ E+ E E + IA N+ G + S S ++ P PG + S++ L
Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETS--SKLLLQATPQFHPGYPLKEKYYGAVGSTLRLH 24344
Query: 923 WREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGT---CYTVGGLIERQKYF--FRIRA 977
P + + E I I T + V ++R+ + ++++
Sbjct: 24345 VMYIGRPVPAMTWFHGQKLLQNSE-----NITIENTEHYTHLVMKNVQRKTHAGKYKVQL 24399
Query: 978 VNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV- 1036
N G + + LD ++ P + A LK+ V+ S PP D
Sbjct: 24400 SNVFGTVDAI-LDVEIQDKPDKPTGPIVIEALLKNSAVI------------SWKPPADDG 24446
Query: 1037 -IWQKDGVPTK-----GRETITKSKNHSQF---LINSTKRSDSGVY-RILLQNEFGEAR- 1085
W + V K G E S S ++N T+ ++G Y R+ QN FG +
Sbjct: 24447 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDP 24504
Query: 1086 ---YDIHVRVADFPRP--PTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDAS 1138
+ + + F +P P + ++ + W P + G +Y + KR+
Sbjct: 24505 LEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWK--PPASDGGAKIRNYYLEKREKK 24562
Query: 1139 TATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDL 1197
W + E + ++V L+ G +Y FRV N G+SE W ++
Sbjct: 24563 QNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESE-------W-------SEI 24608
Query: 1198 SAKLKPYEKKDWR-HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITAN 1256
S + P K D AP F L+ V + T+ C G+P+P V Y+ I A+
Sbjct: 24609 SEPITP--KSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIAD 24666
Query: 1257 SKFW--YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
+ G L+I + T D+ Y V N+ G + +L V
Sbjct: 24667 GLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24714
Score = 75.5 bits (184), Expect = 3e-13
Identities = 136/655 (20%), Positives = 238/655 (36%), Gaps = 106/655 (16%)
Query: 52 SLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISW-KRESGIPIKE 110
S VT N P P+ +++ QPVT G A F A + G +P ISW K E +
Sbjct: 3181 SSVTLYVNAP---EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGF 3237
Query: 111 SAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKML 170
K +D +E+ L L +D+ Y C A ND+ A + SL V E E + + +
Sbjct: 3238 KCKFLHD--GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEM 3294
Query: 171 KKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVE 230
P Q V +E + +V D K+ K +
Sbjct: 3295 PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-----------------KVSWYSKDKK 3337
Query: 231 VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
++ R + + ++T Q + + + G
Sbjct: 3338 IKPSRFFRMTQFEDT-------------------------------YQLEIAEAYPEDEG 3366
Query: 291 TKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIR 350
T Y V SN +VG +A L++ + L K V+ + + AV +
Sbjct: 3367 T-YTFVASN-----------AVGQVSSTANLSLEVQALDRQSSGKDVRESAKSQAVADSS 3414
Query: 351 LSKKEPNFVWK----FNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFS--AEAG 404
+K+E K F G + + + +VS+ + ++D +L + S AE+
Sbjct: 3415 FTKEESKISQKEIKSFQGSSYEYEVQVFESVSQSSIHTAASVQDTQLCHTASLSQIAEST 3474
Query: 405 NLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKD-VTLRWKKDGQLLMHGTK 463
L ++ K +L++V VK A C L + + W +G + +
Sbjct: 3475 ELSKECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESER 3534
Query: 464 YSMNHEGKRAELIIEDAQLSDGGEYTVVAMQD-GDPTEYYSTAIVTVEERLATVKSGMSD 522
+ G L I + QL D G Y+ + D G+ T ++A+++VE ++
Sbjct: 3535 LKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERT---TSAVLSVEGAPESI------ 3585
Query: 523 VHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGK 582
+H E + ++ +L +E +Q+ K +L+ S P + K
Sbjct: 3586 LHERIEQEIE----MEMKEFSSSFLSAEEEGLHSAELQLSKINETLELL--SESPVYPTK 3639
Query: 583 YTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWY 642
+ +GT +FI + D + +G A + V G P PK+ W+
Sbjct: 3640 FDSEKEGT---GPIFIKEVSNAD-------------ISMGDVATLSVTVIGIPKPKIQWF 3683
Query: 643 KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
+G+ +T D L I ED G ND+G + +L +
Sbjct: 3684 FNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3738
Score = 75.5 bits (184), Expect = 3e-13
Identities = 142/714 (19%), Positives = 258/714 (36%), Gaps = 116/714 (16%)
Query: 14 VSMEFSSSTTHVQTFSQTTKIVGEEVVR---RKSSSIVEFFSLVTRSSNIPAGDSV---P 67
+S E +S T++Q Q K + E+V + K S S VTR + A + + P
Sbjct: 26488 ISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKP 26547
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
V Q T A F + G +P W ++ G I + K
Sbjct: 26548 VIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKD-GKAITQGGKY------------- 26593
Query: 128 EPLTSDDSDNYKCIASNDHADA-IYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
L+ D + I D +D+ +YT ++ + G K +K + +KV+
Sbjct: 26594 -KLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA----IKDTEAQKVS 26648
Query: 187 NEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETK 246
+K ++ KK V E I K L +E
Sbjct: 26649 TQKTS-----------------------------EITPQKKAVVQEEIS-QKALRSEE-- 26676
Query: 247 VDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAG 306
+KM K E L ++ K + + K + ++ +
Sbjct: 26677 -----------------IKMSEAKSQEKLALKEEASKVLISEEVKKS----AATSLEKSI 26715
Query: 307 IYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKE 366
++ + S E+ E F +M + E Q V + ++ + W NG E
Sbjct: 26716 VHEEITKTSQASEEVRTHAEIKAFSTQMS---INEGQRLVLKANIAGAT-DVKWVLNGVE 26771
Query: 367 LKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTIDRI---PI 419
L ++Y VS G TL IK A D G + + G + + LT+ +
Sbjct: 26772 LTNSEEYRYGVS--GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAP 26829
Query: 420 KFVSNLKNVRVKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIE 478
F+S ++ + E CE++ + + W K+ + + S++ L I
Sbjct: 26830 AFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIR 26889
Query: 479 DAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLN 538
+A +SD G+YT+ A ++ +V L V+ +V T L +
Sbjct: 26890 NASVSDSGKYTIKAKNFRGQCSATASLMV-----LPLVEEPSREVVLRTSGDTSLQGSFS 26944
Query: 539 DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFI 598
+ V+ + K+ ++ ++ F SM + S + + I
Sbjct: 26945 SQSVQ---MSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 27001
Query: 599 ADPPTIDPSVLEALAAHA-------------ITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
++ ++ S + L A I++ G + F G+P P+VTW G
Sbjct: 27002 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 27061
Query: 646 MEVTEEE--RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
++ +E R +E +D L I + ++D GL L L N+ GS +AT+++ +
Sbjct: 27062 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115
Score = 73.9 bits (180), Expect = 9e-13
Identities = 141/679 (20%), Positives = 253/679 (37%), Gaps = 92/679 (13%)
Query: 54 VTRSSNIPAGDSVP----EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIK 109
VT ++ +PA +P V + VT EG+ + G P ++W RE I+
Sbjct: 880 VTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYRED-YQIE 938
Query: 110 ESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKM 169
S + L + ++DS + C A N+ A + T L + E+ +
Sbjct: 939 SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNE-AGTVSTSCYLAVQVSEEFE---- 993
Query: 170 LKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKV 229
K+ EK E V +D V + T+ ++
Sbjct: 994 -----------KETTAVTEKFTTEEKRFVESRDV--VMTDTSLTE--------EQAGPGE 1032
Query: 230 EVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQM 289
I KP+ K + +VVF C + +P + W K PL Y KQ
Sbjct: 1033 PAAPYFITKPVVQKLVE-GGSVVFGCQVG-GNPKPHVYWKKSGVPLTTGYRYKVSYNKQT 1090
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKR--MSAELTVLDEP---LKFLGEMKPVKVTERQT 344
G + LVIS +DAG Y++ V +K SA ++L+E L + + + T+
Sbjct: 1091 G-ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTA 1149
Query: 345 AVFEIRLSKKEPNFVWKFNGKELKR---------------------DDKYEITVSEDGLT 383
V E ++ + P FV+ KE ++ D ++ I+ E+ L
Sbjct: 1150 FVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLI 1209
Query: 384 HTLKIKDARLSDSGEFSAEAGNLVQKAQLT-IDRIPIKFVSNLKNVRVKERSRACLECEL 442
++ + + + E E G ++ + + F S +KN R+ E C++
Sbjct: 1210 KEIEYRIIKTTLE-ELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKM 1268
Query: 443 TSKDVT-LRWKKDGQLLMHGTKYSMNH-EGKRAELIIEDAQLSDGGEYTVVAMQDGDPTE 500
+ + + W KDG+ + HG +Y M+ + RA L I D G YT A +
Sbjct: 1269 SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA------SN 1322
Query: 501 YYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQ 560
AI + + + + + T P L+ V I P
Sbjct: 1323 IKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSV------SRSPIRMSPARM 1376
Query: 561 IVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVK 620
+ + ++ M P + T ++ VF+ P + LE
Sbjct: 1377 SPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKP--VSFKCLE---------- 1424
Query: 621 VGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVREDSGLI 678
G TA + G+P+P+ W+ DG ++ + +V ++ Q+L+ + DSG
Sbjct: 1425 -GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVP-ATPSDSGEW 1482
Query: 679 LLKLKNDHGSATATLHLSV 697
+ +N G ++ ++ L+V
Sbjct: 1483 TVVAQNRAGRSSISVILTV 1501
Score = 68.2 bits (165), Expect = 5e-11
Identities = 46/164 (28%), Positives = 76/164 (46%), Gaps = 7/164 (4%)
Query: 546 WLKDGKEITD--LPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA---KGTESEASVFIAD 600
W +DG+ I+ LPG+QI KL P++ + G+Y+ +A G + + +
Sbjct: 39 WFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
T P+ ++ L ++TV+ G ++V G P P V +Y+DG E+ + +
Sbjct: 99 AETAPPNFVQRL--QSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEG 156
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
D L I+ EDSG + N G AT+T L V + P
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Score = 67.4 bits (163), Expect = 9e-11
Identities = 105/466 (22%), Positives = 185/466 (39%), Gaps = 44/466 (9%)
Query: 867 LEDTEYEFRVIAVN---KAGPGQPSVPSSSV-----------VAKDPVKPPGLVQDLHVS 912
+E+TE+ ++ N K G+ V S+V + P KP G + +
Sbjct: 24372 IENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV---IE 24428
Query: 913 DSSNSSISLAWREPAE--GDPPSGYILEM-RAEDTKEWSKCTKIPISGTCYTVGGLIERQ 969
+S ++W+ PA+ G + Y++E A++ EW + TC V L E
Sbjct: 24429 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENA 24487
Query: 970 KYFFRIRAVNEAGVGEPVELDKGVRAMPP---PAAP-KFDLSARLKSHMVVRAGTALCIH 1025
Y+FR+ A N G+ +P+E+ V P P AP K ++A K VV A
Sbjct: 24488 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVV----AWKPP 24543
Query: 1026 AAFSGSPPPDVIWQK-DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEA 1084
A+ G+ + +K + K T+ + F + + +R+ +N GE+
Sbjct: 24544 ASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGES 24603
Query: 1085 RYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
+ +++ P +++ + + P+ N + Q + + WY
Sbjct: 24604 EWS---EISEPITPKSDVPI--QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR 24658
Query: 1145 AAERVFSN--KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLK 1202
+ + ++ KY + G Y+ ++A D+ R T N+ +A L+
Sbjct: 24659 QGKEIIADGLKYRIQEFKGG--YHQLIIASVTDDDATVYQVRAT---NQGGSVSGTASLE 24713
Query: 1203 PYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
E H P+ + + LRG+ ++ F G P P +T KG I N +
Sbjct: 24714 -VEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI 24772
Query: 1263 STSGVCTLVIPT-CTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
T +LV P KD+G Y V +N G D+ + L V D D
Sbjct: 24773 VTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPD 24818
Score = 62.8 bits (151), Expect = 2e-09
Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 1/115 (0%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P V+ LK TV+ G+ T+ C G P PTVT Y+ D I ++ F SG+ L+I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD-KSVVASITESLQKKSKHLM 1326
+DSG ++ NE G +SC L V ++ + ++TE + K +
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFV 1011
Score = 62.8 bits (151), Expect = 2e-09
Identities = 127/605 (20%), Positives = 241/605 (39%), Gaps = 84/605 (13%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P ++ + VT G+ A ++ G P I W R G + +S K S + H L
Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR-FGKELIQSRKYKMSSDGRTHTLT 24286
Query: 127 LEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
+ +D Y CIA+N+ + + T S L+ + + LK++ A +
Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGE-VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLR--- 24342
Query: 187 NEKEMLEILSKVPK----------KDFEKVCME----YGFTDFRGLLRKLKEMKKKVE-- 230
++ I VP ++ E + +E Y + + RK K KV+
Sbjct: 24343 --LHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLS 24400
Query: 231 -----VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTE---PLRIQYSLG 282
V+AI ++ ++DK K +V + +++ + + W + Y +
Sbjct: 24401 NVFGTVDAILDVE-IQDKPDKPTGPIVIEALLK---NSAVISWKPPADDGGSWITNYVVE 24456
Query: 283 KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDK---RMSAELTV-LDEPLKFLGEMKPVK 338
K + K+ G ++ LV S +++ I +L+ R+SA+ T + +PL+ +
Sbjct: 24457 KCEAKE-GAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKS 24515
Query: 339 VTERQTAVFE---IRLSKKEPNFVWK--------------FNGKELKRDDKYEITVSE-- 379
E+ A + ++K WK +E K++ +T E
Sbjct: 24516 PFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIR 24575
Query: 380 ----------DGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVR 429
+GL + ++K L E+S + + K+ + I F L+N+
Sbjct: 24576 ETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQ--APHFKEELRNLN 24633
Query: 430 VKERSRACLECELTSKDVTL-RWKKDG-QLLMHGTKYSMNH-EGKRAELIIEDAQLSDGG 486
V+ +S A L C++T + +W + G +++ G KY + +G +LII D
Sbjct: 24634 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDAT 24693
Query: 487 EYTVVAMQDGDPTEYYSTAIVTVEERLATVKS--GMSDVHAATGSPAELCVVLNDEKVEG 544
Y V A G ++ V V ++ K+ GM VHA G + + + +
Sbjct: 24694 VYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPV 24753
Query: 545 VWLKDGKEITDLPG-MQIVKQGAVHKLIFPSMGPEHE--GKYTFRAKG----TESEASVF 597
+ + G+++ D G Q++ + L+FP+ G E + G Y AK + +
Sbjct: 24754 ITWQKGQDLIDNNGHYQVIVTRSFTSLVFPN-GVERKDAGFYVVCAKNRFGIDQKTVELD 24812
Query: 598 IADPP 602
+AD P
Sbjct: 24813 VADVP 24817
Score = 59.7 bits (143), Expect = 2e-08
Identities = 70/309 (22%), Positives = 126/309 (40%), Gaps = 28/309 (9%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTK--GRETITKSKNHS 1058
AP F R ++ + G + SG P P++ W K+ +P +I++S+N
Sbjct: 26828 APAFISQPRSQN---INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVY 26884
Query: 1059 QFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNH 1118
I + SDSG Y I +N G+ + V L L EE V L +
Sbjct: 26885 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV---------LPLVEEPSREVVLRTSG 26935
Query: 1119 SPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+Q + + M A++ + FS+ + + + + + + + +S
Sbjct: 26936 DTSLQGSFSSQSVQMSASKQEASFSS-----FSSS-SASSMTEMKFASMSAQSMSSMQES 26989
Query: 1179 --EPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPH-TVLRGQDCTMTCA 1235
E S + N Q++ ++K+ K R P + L ++ G+ T+ CA
Sbjct: 26990 FVEMSSSSFMGISNMTQLESSTSKML---KAGIRGIPPKIEALPSDISIDEGKVLTVACA 27046
Query: 1236 FLGNPRPTVTLYKGDVNITANS--KFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGK 1293
F G P P VT G I + +F +T + TL+I +D G Y++ + NE G
Sbjct: 27047 FTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGS 27106
Query: 1294 DRSSCTLTV 1302
D ++ + +
Sbjct: 27107 DSATVNIHI 27115
Score = 57.4 bits (137), Expect = 9e-08
Identities = 77/307 (25%), Positives = 121/307 (39%), Gaps = 34/307 (11%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI--TKSKNHS 1058
AP+ L R++SH V G P +V W +GV + I T +
Sbjct: 26068 APRITL--RMRSHRVP-CGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVL 26124
Query: 1059 QFLINSTKRSDSGVYRILLQNEFGEAR--YDIHVRVADFPRPPTNLRLFEEVPNTVTLTW 1116
I DSG YR + N GEA + V D+ + R EEVP +V
Sbjct: 26125 TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRR-DEEVPRSVF--- 26180
Query: 1117 NHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIG 1176
P++ EA+ + + S ++ V S L ++ ++
Sbjct: 26181 ---PELTRT-EAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 26236
Query: 1177 DSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAF 1236
+ + L+ + T + K+K A R +T + TV G+ +C
Sbjct: 26237 EEKSLEEKST-----------TRKIKT------TLAARILTKPRSMTVYEGESARFSCDT 26279
Query: 1237 LGNPRPTVT-LYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDR 1295
G P PTVT L KG V ++ +++ +T T I + D G+YSV+VEN GK
Sbjct: 26280 DGEPVPTVTWLRKGQV-LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQE 26338
Query: 1296 SSCTLTV 1302
+ TLT+
Sbjct: 26339 AEFTLTI 26345
Score = 55.8 bits (133), Expect = 3e-07
Identities = 99/494 (20%), Positives = 176/494 (35%), Gaps = 85/494 (17%)
Query: 316 RMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYE 374
R+ A + + P + +K V V E ++ E +S P W +++ ++
Sbjct: 885 RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQ 944
Query: 375 ITVSEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTID----------RIPIK 420
IT + G+ L I++A DSG F+ EAG + L + + K
Sbjct: 945 ITF-QSGIAR-LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1002
Query: 421 FVSNLKNVRVKERSRACLECELTSKDVT-------------------------------- 448
F + K V+ R + LT +
Sbjct: 1003 FTTEEKRF-VESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1061
Query: 449 -----LRWKKDGQLLMHGTKYSMNHEGKRAE--LIIEDAQLSDGGEYTVVAMQDGDPTEY 501
+ WKK G L G +Y +++ + E L+I D GEYT+V T
Sbjct: 1062 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS- 1120
Query: 502 YSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQI 561
++A + E + ++ T A + E G + ++ + I
Sbjct: 1121 -ASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALI 1179
Query: 562 VKQGAVHKLIFPSMGPEHE-----------GKYTFRAKGT----------ESEASVFIAD 600
K+ A ++ + + E + +R T E + +V I++
Sbjct: 1180 RKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISE 1239
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
++ + + I +G T H K+ G PLPK+ WYKDG + ER M+ +
Sbjct: 1240 SEAVESGFDSRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQ 1297
Query: 661 D-QALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
D +A L I + ED G+ N G+A + L V P P G ++
Sbjct: 1298 DGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV--EPAAPLGAPTYIPTLEPVSR 1355
Query: 720 MKWKAPKDNGGRPV 733
++ +P+ P+
Sbjct: 1356 IRSLSPRSVSRSPI 1369
Score = 54.3 bits (129), Expect = 8e-07
Identities = 33/96 (34%), Positives = 41/96 (42%)
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
HAPR ++ H V GQ+ P V Y V + +SK Y +TSGV TL
Sbjct: 26067 HAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTL 26126
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKD 1306
I C DSG Y + N G+ TL V D
Sbjct: 26127 EILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGD 26162
Score = 52.8 bits (125), Expect = 2e-06
Identities = 66/296 (22%), Positives = 108/296 (36%), Gaps = 50/296 (16%)
Query: 251 VVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL 310
V + C +E D + ++ W G L + KY++ +L + ++ D G Y
Sbjct: 25280 VKYVCKIENYDQSTQVTWYFGVRQLE---NSEKYEITYEDGVAILYVKDITKLDDGTYRC 25336
Query: 311 SVGD-------------------------------KRMSAELTVLDEPLKFLGEMKPVKV 339
V + KR + + +L+ P +F +
Sbjct: 25337 KVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTA 25396
Query: 340 TERQTAVFEIRLS-KKEPNFVWKFNGKELKR-DDKYEITVSEDGLTHTLKIKDARLSDSG 397
+ F + ++ EP+ W +G+++K D+ + T D + L I D
Sbjct: 25397 YVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDA 25456
Query: 398 EFSAEAGNLVQ----KAQLTIDRIPIKFVSNLK--------NVRVKERSRACLECELTS- 444
E++ A N KA+LT+ P S L+ N +E C E ++
Sbjct: 25457 EYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGI 25516
Query: 445 KDVTLRWKKDGQLLMHGTKYSMNHEG-KRAELIIEDAQLSDGGEYTVVAMQDGDPT 499
TL+W+KDGQ L G + HEG L I D D G Y V A T
Sbjct: 25517 PPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGST 25572
Score = 52.4 bits (124), Expect = 3e-06
Identities = 70/313 (22%), Positives = 120/313 (38%), Gaps = 39/313 (12%)
Query: 999 PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-TKG---RETITKS 1054
PAAP F ++ + +V G ++ G+P P V W+K GVP T G + + K
Sbjct: 1033 PAAPYF-ITKPVVQKLV--EGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQ 1089
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+ +I+ T D+G Y I+++N+ GE + L EE + +
Sbjct: 1090 TGECKLVISMTFADDAGEYTIVVRNKHGET--------------SASASLLEEADYELLM 1135
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKY-YFRVVARN 1173
Q A ++ + TA + +E + +Y L +K VV R
Sbjct: 1136 KSQQEMLYQTQVTA-FVQEPKVGETAPGFVYSE--YEKEYEKEQALIRKKMAKDTVVVRT 1192
Query: 1174 EIGDSE-PLDSRDTWLINKDQIQDLSAKLKPYEKKDWRH------------APRFVTPLK 1220
+ D E + S + LI + + + + L+ ++D F + +K
Sbjct: 1193 YVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIK 1252
Query: 1221 PHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN-STSGVCTLVIPTCTLKD 1279
+ +L G T C G P P + YK I ++ + G +L IP +D
Sbjct: 1253 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312
Query: 1280 SGDYSVLVENELG 1292
G Y+ N G
Sbjct: 1313 EGIYTAFASNIKG 1325
Score = 52.4 bits (124), Expect = 3e-06
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFW--YNSTSGVCT 1269
AP F+T ++ G C GNP+P V K V +T ++ YN +G C
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
LVI D+G+Y+++V N+ G+ +S +L
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 51.2 bits (121), Expect = 6e-06
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 13/109 (11%)
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG----VP 1044
L G+R +PP L S + + G L + AF+G P P+V W G
Sbjct: 27015 LKAGIRGIPPKIEA-------LPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQ 27067
Query: 1045 TKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG--EARYDIHVR 1091
+GR I + + + +I ++ D G+Y + L NEFG A +IH+R
Sbjct: 27068 EQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 27116
Score = 50.8 bits (120), Expect = 8e-06
Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 8/197 (4%)
Query: 330 FLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKI 388
F ++ V V E TA FE +S P W +G+ + + +S L I
Sbjct: 8 FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTI 67
Query: 389 KDARLSDSGEFSAEA----GNLVQKAQLTI--DRIPIKFVSNLKNVRVKERSRACLECEL 442
++SG +S +A G A+L + + P FV L+++ V++ S+ L+ +
Sbjct: 68 PAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRV 127
Query: 443 TSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEY 501
T +++ +DG + + ++ EG L+I +A D G Y+V A
Sbjct: 128 TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATS 187
Query: 502 YSTAIVTVEERLATVKS 518
+ +V EE + K+
Sbjct: 188 TAELLVQGEEEVPAKKT 204
Score = 50.4 bits (119), Expect = 1e-05
Identities = 25/96 (26%), Positives = 49/96 (51%)
Query: 1207 KDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG 1266
K+ AP F++ + + GQ+ TC G P P + +K ++ I+ +S + +
Sbjct: 26823 KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN 26882
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
V +L I ++ DSG Y++ +N G+ ++ +L V
Sbjct: 26883 VYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918
Score = 50.1 bits (118), Expect = 1e-05
Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVRE 673
++ V G TA + G P+P+V+W++DG ++ V + + +A LTI +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 674 DSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
+SG LK N G AT+T L V PP
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 50.1 bits (118), Expect = 1e-05
Identities = 84/364 (23%), Positives = 140/364 (38%), Gaps = 55/364 (15%)
Query: 384 HTLKIKD-------ARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSN-LKNVRVKERSR 435
HTL KD AR+S G ++ G V A++ + I I VS + + +E
Sbjct: 25222 HTLIKKDLNMVVSAARISCGGAIRSQKG--VSVAKVKVASIEIGPVSGQIMHAVGEEGGH 25279
Query: 436 ACLECELTSKDVTLR--WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAM 493
C++ + D + + W + L + KY + +E A L ++D D G Y +
Sbjct: 25280 VKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 25339
Query: 494 QD-GDPTEYYSTAIVTVEE-------RLATVKSGMSDVHAATGSPAELCVVLNDEKV--- 542
D G+ + Y + V E R +D P E + L ++
Sbjct: 25340 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 25399
Query: 543 EGV---------------WLKDGKEITDLPGMQIVK-----QGAVHKLIFPSMGPEHEGK 582
E V W K G++I PG K +++L S+ + + +
Sbjct: 25400 ENVRFGVTITVHPEPHVTWYKSGQKIK--PGDNDKKYTFESDKGLYQLTINSVTTDDDAE 25457
Query: 583 YTFRAKGTESEAS------VFIADPPTIDP--SVLEALAAHAITVKVGHTAHIKVPFRGK 634
YT A+ E S V + PPT + + L A+A + G + ++ G
Sbjct: 25458 YTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANA-ECQEGQSVCFEIRVSGI 25516
Query: 635 PLPKVTWYKDGMEVTEEERVSM-ERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
P P + W KDG ++ + + G D L I + + ED+G + N GS +
Sbjct: 25517 PPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQA 25576
Query: 694 HLSV 697
HL V
Sbjct: 25577 HLQV 25580
Score = 48.9 bits (115), Expect = 3e-05
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P FV L+ TV +G + G P P V Y+ I ++ F + + +L+I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD------KSVV--ASITESLQKK 1321
+DSG YSV N +G+ S+ L V +++ K++V A I+ES Q +
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 48.9 bits (115), Expect = 3e-05
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 3/99 (3%)
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTK---GRETITK 1053
PP + + RL ++ + G ++C SG PPP + W+KDG P E I +
Sbjct: 25482 PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHE 25541
Query: 1054 SKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV 1092
++ I T D+G YR+ N G H++V
Sbjct: 25542 GLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25580
Score = 47.8 bits (112), Expect = 7e-05
Identities = 78/309 (25%), Positives = 120/309 (38%), Gaps = 29/309 (9%)
Query: 354 KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSD-SGEFSAEA----GNLVQ 408
KE N W F K + D+K++ +D T+TL I D GE+ EA G
Sbjct: 4462 KEVN--WYFENKLVPSDEKFKCL--QDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTAT 4517
Query: 409 KAQLTIDRIPIKFVSN-LKNVRVKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSM 466
A+LT+ + + ++ + V A CE+ S +V +W K G+ + K S+
Sbjct: 4518 SAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSI 4577
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
+ L I Q+ D GEYT A + +T VTV V+ + +
Sbjct: 4578 RSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPE 4637
Query: 527 TGSPAELCVVL------NDEKVEGVWLKDGKE--ITDLPGMQIVKQGAV-------HKLI 571
L VL + KVE L+ K+ + + P + V++ V K+
Sbjct: 4638 PKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIP 4697
Query: 572 FPSMGPEHEGKYTFRA--KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKV 629
P+ PE + A + EA V PP ++P A + V VG A K
Sbjct: 4698 EPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPV-VGKKAEAKA 4756
Query: 630 PFRGKPLPK 638
P PK
Sbjct: 4757 PKEEAAKPK 4765
Score = 47.8 bits (112), Expect = 7e-05
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA---NSKFWYNSTSGVCT 1269
P F PL T G++ +P P VT YK I + K+ + S G+
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25444
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L I + T D +Y+V+ N+ G+D LTV
Sbjct: 25445 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 47.4 bits (111), Expect = 9e-05
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSK-FWYNSTSGVCTL 1270
AP+ ++ TV +G D +G P P YK V I + + +WY VC L
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCEL 2090
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQ 1319
VI T +DS V N G+ S L V K + + T+ LQ
Sbjct: 2091 VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ----LITFTQELQ 2135
Score = 47.4 bits (111), Expect = 9e-05
Identities = 55/226 (24%), Positives = 100/226 (44%), Gaps = 30/226 (13%)
Query: 220 RKLKEMKKKVEVEAIRILK-------PLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGT 272
R +K++K++ + +R+L+ PL +K V V F + + P + W K
Sbjct: 25366 RTMKKIKRRTDT--MRLLERPPEFTLPLYNKTAYVGENVRFGVTITVH-PEPHVTWYKSG 25422
Query: 273 EPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPL 328
+ ++ + KY + Y L I++V +D Y++ G+ A+LTV P
Sbjct: 25423 QKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPP 25482
Query: 329 KFLGEMKPV--------KVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSE 379
++P+ + E Q+ FEIR+S P W+ +G+ L EI
Sbjct: 25483 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII--H 25540
Query: 380 DGLT-HTLKIKDARLSDSGEF----SAEAGNLVQKAQLTIDRIPIK 420
+GL + L I+D D+G + + AG+ +A L ++R+ K
Sbjct: 25541 EGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYK 25586
Score = 45.4 bits (106), Expect = 4e-04
Identities = 69/296 (23%), Positives = 111/296 (37%), Gaps = 39/296 (13%)
Query: 1032 PPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P +VIW K + + GR I +I + D+G Y L + + + +H
Sbjct: 6184 PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVH 6243
Query: 1090 VRVADFPRPPTNLRLFE-EVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAER 1148
A+F P NL + E E V S VQ KRD T
Sbjct: 6244 ELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQ---------WKRDDKTLE------- 6287
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKD 1208
+KY V + G+K R + L T+++ + +A L EK
Sbjct: 6288 -SGDKYDV--IADGKK-------RVLVVKDATLQDMGTYVVMVGAAR-AAAHLTVIEKL- 6335
Query: 1209 WRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVC 1268
R V PLK V Q+ C + ++ + I +SK+ V
Sbjct: 6336 -----RIVVPLKDTRVKEQQEVVFNCE-VNTEGAKAKWFRNEEAIFDSSKYIILQKDLVY 6389
Query: 1269 TLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASI--TESLQKKS 1322
TL I L D +Y+V + N G++ S + +++D +V + E+++KKS
Sbjct: 6390 TLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKS 6445
Score = 45.4 bits (106), Expect = 4e-04
Identities = 74/329 (22%), Positives = 131/329 (39%), Gaps = 40/329 (12%)
Query: 369 RDDKYEITVSEDGLTHTLKIKDARLSDSG--EFSAEAGNLVQKAQLTIDRIPIKFVSNLK 426
R+ K ++T + + L+ A + + E S E + +K + T+ + ++ +
Sbjct: 26207 REVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTL---AARILTKPR 26263
Query: 427 NVRVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDG 485
++ V E A C+ + V T+ W + GQ+L ++ + ++ I Q SD
Sbjct: 26264 SMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDE 26323
Query: 486 GEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGV 545
G Y+VV E T +T+++ T K+ S + P V + E V
Sbjct: 26324 GNYSVVVENSEGKQEAEFT--LTIQKARVTEKAVTSPPRVKSPEPR----VKSPEAV--- 26374
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
K K + + + K + P+ E K T TE + ++ PP I
Sbjct: 26375 --KSPKRVKS-------PEPSHPKAVSPT-----ETKPT----PTEKVQHLPVSAPPKI- 26415
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL- 664
L+A A+ I K+ V R K +VTWYKDG ++ E D
Sbjct: 26416 TQFLKAEASKEI-AKLTCVVESSV-LRAK---EVTWYKDGKKLKENGHFQFHYSADGTYE 26470
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATL 693
L I+N D G + ++ + G++ L
Sbjct: 26471 LKINNLTESDQGEYVCEISGEGGTSKTNL 26499
Score = 45.1 bits (105), Expect = 5e-04
Identities = 32/106 (30%), Positives = 42/106 (39%)
Query: 1197 LSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITAN 1256
++ K +P + P VT L+ TV G PRPT K IT
Sbjct: 26531 VTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG 26590
Query: 1257 SKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
K+ + G L I DSG Y+ V+N G SSC LT+
Sbjct: 26591 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26636
Score = 43.9 bits (102), Expect = 0.001
Identities = 40/196 (20%), Positives = 77/196 (39%), Gaps = 14/196 (7%)
Query: 509 VEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVH 568
++E + + + D + G L + + K E W + K + + ++ +
Sbjct: 4430 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAK-EVNWYFENKLVPSDEKFKCLQDQNTY 4488
Query: 569 KLIFPSMGPE-HEGKYTFRA------KGTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
L+ + E H+G+Y A T ++ +V P I + + V +
Sbjct: 4489 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKI------EPLEVAL 4542
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
GH A + P + W+K G E+ E ++ S+ + + L I D G K
Sbjct: 4543 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCK 4602
Query: 682 LKNDHGSATATLHLSV 697
N++GS + T L+V
Sbjct: 4603 ASNEYGSVSCTATLTV 4618
Score = 43.1 bits (100), Expect = 0.002
Identities = 46/213 (21%), Positives = 81/213 (38%), Gaps = 6/213 (2%)
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMS---DVHAATGSPAELCVVLNDEKVEGV 545
+V + G +AI T+++ L+ S V A T P+E V +
Sbjct: 776 SVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQF 835
Query: 546 WLKDGKEI-TDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
D + G+++ K+ V E + AK TE+ + P
Sbjct: 836 PFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVT 895
Query: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL 664
P+++ L +TV G + ++ G P P VTWY++ ++ + A
Sbjct: 896 PPTLVSGLKN--VTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIAR 953
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
L I EDSG N+ G+ + + +L+V
Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 43.1 bits (100), Expect = 0.002
Identities = 73/336 (21%), Positives = 119/336 (35%), Gaps = 70/336 (20%)
Query: 1030 GSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
G P P+ W DG V + + K +I SDSG + ++ QN G +
Sbjct: 1436 GRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSI 1495
Query: 1087 DI--HVRVADFPRPP--------TNLRLFEEVPNTVTLTWNHSPDVQ------------- 1123
+ V + P N++ + V T N +PD+
Sbjct: 1496 SVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKY 1555
Query: 1124 -------EDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTG-----------------L 1159
GEA I + + WYTA + + T +
Sbjct: 1556 PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLI 1615
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSR---DTWLINKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
+P Y + +A E+ EPL R + W + + D + KP+ KK +
Sbjct: 1616 IPRGTYRAKEIAAPEL---EPLHLRYGQEQW--EEGDLYDKEKQQKPFFKKK-------L 1663
Query: 1217 TPLKPHTVLRGQ-DCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
T L+ +C +T +G+P V + A ++ + G C+L
Sbjct: 1664 TSLRLKRFGPAHFECRLTP--IGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVA 1721
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVV 1311
+DSG + N+ G D +S TL V KD+KS+V
Sbjct: 1722 YSRDSGIITCRATNKYGTDHTSATLIV--KDEKSLV 1755
Score = 42.7 bits (99), Expect = 0.002
Identities = 57/273 (20%), Positives = 106/273 (38%), Gaps = 30/273 (10%)
Query: 1032 PPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P V W KD + R I K K + LI ST+ SD+G Y ++ A+ +
Sbjct: 3038 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3097
Query: 1090 VRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERV 1149
R +++ E+ V N ++D +AH+ +D + ER
Sbjct: 3098 GRDVRIRSIKKEVQVIEKQRAVVEFEVN-----EDDVDAHWY---KDGIEIN-FQVQER- 3147
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
+KY V R + R I ++ D+ + + ++ + E
Sbjct: 3148 --HKYVVE----------RRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPE---- 3191
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
P+ + L+P TV G+ G P+P ++ YK + ++ K + T
Sbjct: 3192 --PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3249
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L++ +D+ Y+ +N+ G +S +L+V
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 42.4 bits (98), Expect = 0.003
Identities = 25/112 (22%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P F+ + + G T++ +G P+P + + V +T ++ + + +L+I
Sbjct: 3649 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3708
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK----DDKSVVASITESLQK 1320
L+D G+Y+ + N+ GK S L + K D +++ +SL+K
Sbjct: 3709 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEK 3760
Score = 42.4 bits (98), Expect = 0.003
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 1198 SAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS 1257
SA K EK P F+ LKP +G +G P PTVT +K + + +
Sbjct: 3752 SAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSV 3811
Query: 1258 KFW-YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKD 1306
+ ++ +G T ++ +DSG Y EN LG+ + L V +D
Sbjct: 3812 YYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLED 3861
Score = 42.0 bits (97), Expect = 0.004
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 588 KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGME 647
K +E + V P T+D + L + V G + + KP +V WY +G+E
Sbjct: 26049 KTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVE 26108
Query: 648 VTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSAT--ATLHLS 696
+ E ++ L I +C +DSG N G A+ ATL ++
Sbjct: 26109 LQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVT 26159
Score = 40.0 bits (92), Expect = 0.015
Identities = 33/111 (29%), Positives = 45/111 (40%), Gaps = 15/111 (13%)
Query: 1002 PKFDLSARLKSHMV---VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE-----TITK 1053
P+F L K+ V VR G + +H P P V W K G K + T
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVH------PEPHVTWYKSGQKIKPGDNDKKYTFES 25438
Query: 1054 SKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRL 1104
K Q INS D Y ++ +N++GE + V P PPT+ L
Sbjct: 25439 DKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP-PPTDSTL 25488
Score = 39.7 bits (91), Expect = 0.019
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS--KFWYNSTSGVCT 1269
AP F PL+ VL G T G P P V+ ++ I+ ++ + + G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L IP T +SG YS+ N G+ S+ L V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 39.7 bits (91), Expect = 0.019
Identities = 62/301 (20%), Positives = 101/301 (33%), Gaps = 54/301 (17%)
Query: 1008 ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKS---KNHSQFLINS 1064
+R+K++ ++ G + H SG P P + W KDG K E + I
Sbjct: 1249 SRIKNYRILE-GMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPV 1307
Query: 1065 TKRSDSGVYRILLQNEFGEARYD--IHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDV 1122
D G+Y N G A ++V A PT + E V +L+
Sbjct: 1308 VLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLS------- 1360
Query: 1123 QEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
R S + + R+ + + + P R + L+
Sbjct: 1361 -----------PRSVSRSPIRMSPARMSPARMSPARMSPAR-----------MSPGRRLE 1398
Query: 1183 SRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP 1242
D + Q++ L + P FV L GQ +G P P
Sbjct: 1399 ETD-----ESQLERL-------------YKPVFVLKPVSFKCLEGQTARFDLKVVGRPMP 1440
Query: 1243 -TVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLT 1301
T + G + + G +L+I T DSG+++V+ +N G+ S LT
Sbjct: 1441 ETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILT 1500
Query: 1302 V 1302
V
Sbjct: 1501 V 1501
Score = 39.7 bits (91), Expect = 0.019
Identities = 42/183 (22%), Positives = 70/183 (38%), Gaps = 14/183 (7%)
Query: 9 MLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAG----- 63
+L E + E + + + G + S I E L++ S P
Sbjct: 3585 ILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEK 3644
Query: 64 -DSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKE 122
+ P F+++ GD A V G KP I W +G+ + SA + +
Sbjct: 3645 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFF-NGVLLTPSADYKFVFDGDD 3703
Query: 123 HVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV-TEGQEKMDFK------KMLKKRAP 175
H L + +D Y C+ASND+ I + L + ++G+ D + K L+K
Sbjct: 3704 HSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 3763
Query: 176 PAP 178
P P
Sbjct: 3764 PCP 3766
Score = 39.7 bits (91), Expect = 0.019
Identities = 32/131 (24%), Positives = 52/131 (39%), Gaps = 6/131 (4%)
Query: 52 SLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKES 111
S V +S G P F+++ +P+ +G A+F V G P ++W +E+ +
Sbjct: 3752 SAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENK---QLC 3808
Query: 112 AKIFYDSI---NKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKK 168
++Y I N + +DS Y C A N ++ LLV M
Sbjct: 3809 TSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 3868
Query: 169 MLKKRAPPAPK 179
K P AP+
Sbjct: 3869 CKAKSTPEAPE 3879
Score = 39.7 bits (91), Expect = 0.019
Identities = 49/220 (22%), Positives = 90/220 (40%), Gaps = 24/220 (10%)
Query: 80 EGDKAVFRARVQGNAKPHISWKRE-SGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNY 138
EG F RV G P + W+++ + + + +I ++ ++ + L + +D+ Y
Sbjct: 25503 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD-YYALHIRDTLPEDTGYY 25561
Query: 139 KCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANEKEMLEILS-- 196
+ A+N L V E++ +KK K + QK++ M EILS
Sbjct: 25562 RVTATNTAGSTSCQAHLQV----ERLRYKKQEFKSKEEHERHVQKQIDKTLRMAEILSGT 25617
Query: 197 ------KVPKKDFEKVCMEY----GFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETK 246
+V K+ + + Y +G R E+++K E +R+ + +
Sbjct: 25618 ESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFR--LEIEEKKEERKLRMPYDVPEPRKY 25675
Query: 247 VDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSL-GKYD 285
TT+ D ++ P M W K +R QY + GK D
Sbjct: 25676 KQTTIEEDQRIKQFVPMSDMKWYK---KIRDQYEMPGKLD 25712
Score = 39.3 bits (90), Expect = 0.025
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 3/89 (3%)
Query: 618 TVKVGHTAHIKVPFRGKPLPKVTWYKDGMEV---TEEERVSMERGEDQALLTISNCVRED 674
T VG V P P VTWYK G ++ +++ + E + LTI++ +D
Sbjct: 25395 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25454
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKP 703
+ +N +G + L+V P P
Sbjct: 25455 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 25483
Score = 38.5 bits (88), Expect = 0.043
Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 1/106 (0%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV-L 125
P F + Q V EG A F A + G P +SW R+ + + S + L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171
+ +T +S Y A+N A T LLV +F + L+
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ 111
Score = 38.5 bits (88), Expect = 0.043
Identities = 32/145 (22%), Positives = 60/145 (41%), Gaps = 10/145 (6%)
Query: 17 EFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGDSVPEFVEKPQPV 76
++ +++ + F + + V + RR I R+ + + PEF
Sbjct: 25341 DYGEDSSYAELFVKGVREVYDYYCRRTMKKIKR------RTDTMRLLERPPEFTLPLYNK 25394
Query: 77 TAPEGDKAVFRARVQGNAKPHISWKRESGIPIK---ESAKIFYDSINKEHVLKLEPLTSD 133
TA G+ F + + +PH++W + SG IK K ++S + L + +T+D
Sbjct: 25395 TAYVGENVRFGVTITVHPEPHVTWYK-SGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25453
Query: 134 DSDNYKCIASNDHADAIYTVSLLVT 158
D Y +A N + + L VT
Sbjct: 25454 DDAEYTVVARNKYGEDSCKAKLTVT 25478
Score = 37.7 bits (86), Expect = 0.074
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 81 GDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKC 140
G+ V G +P+ISW ++ G P+K++ ++ + VL ++ DD Y
Sbjct: 18021 GEDLKIEIPVIGRPRPNISWVKD-GEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 18079
Query: 141 IASNDHADAIYTVSLLVTE 159
A+N A +S++V E
Sbjct: 18080 TATNSAGTATENLSVIVLE 18098
Score = 37.4 bits (85), Expect = 0.096
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 1/98 (1%)
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
+ P V +P VL G+ C G P+P V Y I + +F G+
Sbjct: 1792 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHY 1850
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
L I C D+G+ V EN G L + ++D
Sbjct: 1851 LDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1888
Score = 37.0 bits (84), Expect = 0.13
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 1029 SGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG 1082
+G P P IW KDG + G+ +++ K I+ T SDSG+Y ++N G
Sbjct: 26571 TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAG 26626
Score = 35.8 bits (81), Expect = 0.28
Identities = 25/93 (26%), Positives = 36/93 (38%)
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
R AP ++P V G TC P +K I + K S+ + +
Sbjct: 4526 RAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISS 4585
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L I + D G+Y+ NE G + TLTV
Sbjct: 4586 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618
Score = 35.4 bits (80), Expect = 0.37
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDG----VPTKGRETITKSKNHSQFLINSTKRSD 1069
+VV G+ A SG P P+V W +DG T I+ S ++ I + +++
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKAN 74
Query: 1070 SGVYRILLQNEFGEARYDIHVRVADFPRPP 1099
SG Y + N G+A + V PP
Sbjct: 75 SGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 35.4 bits (80), Expect = 0.37
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 4/119 (3%)
Query: 54 VTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAK 113
+T S++P P F E+ + + A +V G+ KP + W R+ I + K
Sbjct: 24612 ITPKSDVPI--QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 24669
Query: 114 I-FYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171
+ H L + +T DD+ Y+ A+N T SL V E K+ K L+
Sbjct: 24670 YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV-EVPAKIHLPKTLE 24727
Score = 35.0 bits (79), Expect = 0.48
Identities = 29/101 (28%), Positives = 41/101 (40%), Gaps = 7/101 (6%)
Query: 1030 GSPPPDVIWQKDG--VPTKGRETITKSKNHS-QFLINSTKRSDSGVYRILLQNEFGEARY 1086
G P P V W K+ + T TI + N S F++N +R DSG+Y +N GE+
Sbjct: 3792 GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTC 3851
Query: 1087 DIHVRV----ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQ 1123
+ V D P + E P T P V+
Sbjct: 3852 AAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVE 3892
Score = 34.3 bits (77), Expect = 0.82
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDG---VPTK-GRETITKSKNHSQFLINSTKRSDSG 1071
++ G+ L + +G+P PD++W K+ VP K + I +K + I+ST DS
Sbjct: 1521 IKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSA 1580
Query: 1072 VYRILLQNEFGE--ARYDIHVRVADFPRPPTNLRL 1104
Y N+ G R ++V V +F P +L
Sbjct: 1581 WYTATAINKAGRDTTRCKVNVEV-EFAEPEPERKL 1614
Score = 33.9 bits (76), Expect = 1.1
Identities = 30/134 (22%), Positives = 62/134 (46%), Gaps = 12/134 (8%)
Query: 296 VISNVNMNDAGIYSLSVGDKR-----MSAELTVLDEPLKFLGEMKPV----KVTERQTAV 346
VI+N+ + ++ + +++ S + ++ + L ++KP V Q
Sbjct: 16884 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 16943
Query: 347 FEIRLS-KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
E+ +S + +P W +G LK+ + +T S D LT TL IK+ D G++ N
Sbjct: 16944 IEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD-LT-TLSIKETHKDDGGQYGITVAN 17001
Query: 406 LVQKAQLTIDRIPI 419
+V + +I+ + +
Sbjct: 17002 VVGQKTASIEIVTL 17015
Score = 33.5 bits (75), Expect = 1.4
Identities = 36/161 (22%), Positives = 65/161 (40%), Gaps = 12/161 (7%)
Query: 973 FRIRAVNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGS 1031
+ ++A N +G EL PP + RL+S M VR G+ + + +G
Sbjct: 78 YSLKATNGSGQATSTAELLVKAETAPP------NFVQRLQS-MTVRQGSQVRLQVRVTGI 130
Query: 1032 PPPDVIWQKDGVPTKGR--ETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P P V + +DG + I++ + LI DSG Y + N G A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAE 190
Query: 1090 VRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHY 1130
+ V P + + + +T ++ + +++ EAH+
Sbjct: 191 LLVQGEEEVPA--KKTKTIVSTAQISESRQTRIEKKIEAHF 229
Score = 33.1 bits (74), Expect = 1.8
Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 76 VTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDS 135
V A GD V G KP ++WK+ I +K++ ++ +++ +L + DS
Sbjct: 14770 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQI-LKQTQRVNFETTATSTILNINECVRSDS 14828
Query: 136 DNYKCIASN 144
Y A N
Sbjct: 14829 GPYPLTARN 14837
Score = 33.1 bits (74), Expect = 1.8
Identities = 33/135 (24%), Positives = 53/135 (39%), Gaps = 17/135 (12%)
Query: 26 QTFSQT--TKIVGEEVVRRKSSSIVEFFSLVTR----SSNIPAGD-SVPEFVEKPQ---- 74
QT+S +K EV + K S++EF S + G +V E + P+
Sbjct: 21202 QTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLS 21261
Query: 75 -----PVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEP 129
VT G +G KP ISW ++ G+P+KES + + + L ++
Sbjct: 21262 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKD-GLPLKESEFVRFSKTENKITLSIKN 21320
Query: 130 LTSDDSDNYKCIASN 144
+ Y I N
Sbjct: 21321 AKKEHGGKYTVILDN 21335
Score = 33.1 bits (74), Expect = 1.8
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEF 399
P WK LK D+ IT ++D TL +KD+ DSG +
Sbjct: 22372 PKVTWKLEEMRLKETDRVSITTTKD--RTTLTVKDSMRGDSGRY 22413
Score = 32.7 bits (73), Expect = 2.4
Identities = 64/277 (23%), Positives = 104/277 (37%), Gaps = 48/277 (17%)
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEF---GEARYDIHVRV 1092
V W KDG K K K + G RIL+ N+ EA Y VR
Sbjct: 6099 VKWFKDGAEIK------KGKKYDII--------SKGAVRILVINKCLLDDEAEYSCEVRT 6144
Query: 1093 ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYII-MKRDASTATWYTAAERVF- 1150
A T L EE T L + +V E + + + + WY E +
Sbjct: 6145 ARTSGMLTVLE--EEAVFTKNLA---NIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIE 6199
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR--DTWLINKDQIQDLSAKLKPYEKKD 1208
+ +Y + L GRK V+ + D+ + R + K ++ +L+A+
Sbjct: 6200 TGRYEI--LTEGRKRIL-VIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAE-------- 6248
Query: 1209 WRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVC 1268
F++ + +L G+ C+ P V + D + + K+ +
Sbjct: 6249 ------FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKKR 6301
Query: 1269 TLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
LV+ TL+D G Y V+V G R++ LTV +K
Sbjct: 6302 VLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6334
Score = 32.3 bits (72), Expect = 3.1
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query: 280 SLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMK 335
SL K ++ + +L++ NVN D+G Y L+V G K + VLD P G +
Sbjct: 15596 SLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTP----GPPQ 15651
Query: 336 PVKVTE 341
+KV E
Sbjct: 15652 DLKVKE 15657
Score = 32.0 bits (71), Expect = 4.0
Identities = 15/54 (27%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 1247 YKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
Y DV + +N K+ S G L + T +D G+YS +++ + +++C L
Sbjct: 2254 YHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK----KTTCKL 2303
Score = 32.0 bits (71), Expect = 4.0
Identities = 57/243 (23%), Positives = 90/243 (37%), Gaps = 27/243 (11%)
Query: 1067 RSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDG 1126
RS+ V+ + L++ E ++ + DF T+ LF + P V T E+G
Sbjct: 5939 RSEGKVHTLTLRDVKLEDAGEVQLTAKDFK---THANLFVKEP-PVEFTKPLEDQTVEEG 5994
Query: 1127 EAHYII--MKRDASTATWY-TAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ + R+ + W+ E + S KY + GR V + I D P D
Sbjct: 5995 ATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVA--DGR------VRKLVIHDCTPEDI 6046
Query: 1184 RDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPT 1243
+ KD + + P + F+ PL V + C L
Sbjct: 6047 KTYTCDAKDFKTSCNLNVVPPHVE-------FLRPLTDLQVREKEMARFECE-LSRENAK 6098
Query: 1244 VTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVY 1303
V +K I K+ S V LVI C L D +YS E+ R+S LTV
Sbjct: 6099 VKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC----EVRTARTSGMLTVL 6154
Query: 1304 DKD 1306
+++
Sbjct: 6155 EEE 6157
Score = 32.0 bits (71), Expect = 4.0
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 11/70 (15%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAEL 321
PNV +W K LR + + D ++ L I N N ND+G Y+L++ + +A L
Sbjct: 19911 PNV--LWSKPDTDLRTRAYVDTTD-----SRTSLTIENANRNDSGKYTLTIQNVLSAASL 19963
Query: 322 T----VLDEP 327
T VLD P
Sbjct: 19964 TLVVKVLDTP 19973
Score = 32.0 bits (71), Expect = 4.0
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 9/70 (12%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P +W K L + + D+ + L + N N NDAG Y+L+V G K +
Sbjct: 22080 PTPTAVWSKPDSNLSL-----RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSI 22134
Query: 318 SAELTVLDEP 327
+ + VLD P
Sbjct: 22135 TFTVKVLDTP 22144
Score = 31.6 bits (70), Expect = 5.3
Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 11/129 (8%)
Query: 224 EMKKKVEVEAIRI-LKPLEDKETKVDTTVVFDCIME-LKDPNVKMIWIKGTEPLRIQYSL 281
E ++K+ ++ + +K +E K TTV F I+ + P K W ++
Sbjct: 11195 ECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTDEH- 11251
Query: 282 GKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMKPV 337
Y V+ +L I N D G Y ++V G K ++ LTVLD P G + +
Sbjct: 11252 --YTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINIL 11309
Query: 338 KVTERQTAV 346
VT +
Sbjct: 11310 DVTPEHMTI 11318
Score = 31.2 bits (69), Expect = 6.9
Identities = 19/84 (22%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 1012 SHMVVRAGTALCIHAAFSGSPPPDVIWQKDGV---PTKGRETITKSKNHSQFLINSTKRS 1068
S+ + G + G P P + W +GV P+ + + +HS +I TK
Sbjct: 3656 SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHS-LIILFTKLE 3714
Query: 1069 DSGVYRILLQNEFGEARYDIHVRV 1092
D G Y + N++G+ ++++
Sbjct: 3715 DEGEYTCMASNDYGKTICSAYLKI 3738
Score = 30.8 bits (68), Expect = 9.0
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
Query: 277 IQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPLKFLG 332
IQ SL + + Q G Y L+I+ D+G YS+ SVG +AEL V E
Sbjct: 144 IQSSLD-FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Query: 333 EMKPVKVTERQTAVFEIRLSKK 354
+ K + T + + + R+ KK
Sbjct: 203 KTKTIVSTAQISESRQTRIEKK 224
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 423 bits (1087), Expect = e-118
Identities = 299/1086 (27%), Positives = 497/1086 (45%), Gaps = 54/1086 (4%)
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTV------------SLLVTEGQEKMDFKK 168
++ +L ++ +D+ NY C + D V +L + EG EK +F
Sbjct: 6143 RKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEG-EKAEFVC 6201
Query: 169 MLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDF---EKVCMEYG-FTDFRGLLRKLKE 224
+ K + P K+ K + ++++ K+ + + G + G R
Sbjct: 6202 SISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAH 6261
Query: 225 MKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKY 284
+ +E +RI+ PL+D K VVF+C E+ K W + E + + KY
Sbjct: 6262 L---TVIEKLRIVVPLKDTRVKEQQEVVFNC--EVNTEGAKAKWFRNEEAI---FDSSKY 6313
Query: 285 DVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR-----MSAELTVLDEPLKFLGEMKPVKV 339
+ Q Y L I + +++D Y++S+ + R +A L V +E L+ + +K ++
Sbjct: 6314 IILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIET 6373
Query: 340 TERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEF 399
E+++ F ++++ W NG+E+ D++ V D H L IKD D GE+
Sbjct: 6374 MEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRV--DKYKHMLTIKDCGFPDEGEY 6431
Query: 400 SAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLM 459
AG A+L I P +FV +L++ V E A C+L+ + ++W ++G+ +
Sbjct: 6432 IVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIK 6491
Query: 460 HGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSG 519
G KY +G LII+D +L D EY ++D S A + VEE +
Sbjct: 6492 EGKKYKFEKDGSIHRLIIKDCRLDDECEYAC-GVEDRK-----SRARLFVEEIPVEIIRP 6545
Query: 520 MSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEH 579
D+ A G+ LN +KVE WL++ + Q++ +G +H+L + P
Sbjct: 6546 PQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRD 6605
Query: 580 EGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKV 639
+G+Y F AK E+ A + +A P I A + V VG + VP+ P +
Sbjct: 6606 QGEYRFIAKDKEARAKLELAAAPKIKT------ADQDLVVDVGKPLTMVVPYDAYPKAEA 6659
Query: 640 TWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLD 699
W+K+ ++ + +++ +Q I + D G + L+N HG A ++L V+D
Sbjct: 6660 EWFKENEPLSTK---TIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVID 6716
Query: 700 RPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVT 759
P P + +E E V + W+ P +GG + ++VERR + +K+W+ +
Sbjct: 6717 VPGPVRN-LEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE 6775
Query: 760 NFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAV 818
T + G Y FR+ A N G +P+ET+ V A + + PG +TDV + V
Sbjct: 6776 FTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGV 6835
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
++TW P DGGA + Y++E R K S W + TV ++E EY FRV A
Sbjct: 6836 SLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRA 6895
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYI 936
N+ G G+PS + V DP++ P +L SD + SS+ L W P + G P GYI
Sbjct: 6896 QNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 6955
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
+E E W +C + Y V GL + KY +R+ A N+AGV +P E+ + A
Sbjct: 6956 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 7015
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIW--QKDGVPTKGRETITKS 1054
P DLSA K + V + I +G P P W + T R +
Sbjct: 7016 DAFVEPTMDLSA-FKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTL 7074
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+++ +I+ ++RSD G+Y + L+N +I V V P P L+ + ++V L
Sbjct: 7075 SAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHL 7134
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNE 1174
TW D Y++ KR+ S TW + V ++TV L+ G++Y F+V ARN+
Sbjct: 7135 TWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNK 7194
Query: 1175 IGDSEP 1180
G EP
Sbjct: 7195 CGPGEP 7200
Score = 380 bits (977), Expect = e-105
Identities = 300/1056 (28%), Positives = 483/1056 (45%), Gaps = 93/1056 (8%)
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+MG KY ++ VN+ YS S+ + + + D L+ ++K VT R A
Sbjct: 23036 KMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD--LELADDLKKT-VTIRAGASL 23092
Query: 348 EIRLS---KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKD-ARLSDSGEFSAEA 403
+ +S + P W G +L + T S ++L I D D+G+++ EA
Sbjct: 23093 RLMVSVSGRPPPVITWSKQGIDLASRAIIDTTES-----YSLLIVDKVNRYDAGKYTIEA 23147
Query: 404 GNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWK---KDGQLLMH 460
N K T+ +V+VKE SR VT+ W+ DG ++
Sbjct: 23148 ENQSGKKSATVLVKVYDTPGPCPSVKVKEVSR---------DSVTITWEIPTIDGGAPVN 23198
Query: 461 GTKYSMNHEGKRA---------ELIIEDAQLSDGGEYTVVAMQD-----GDPTEYYSTAI 506
RA + + + L +G Y + + G+P E S A+
Sbjct: 23199 NYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE-TSDAV 23257
Query: 507 VTVEERLATVKSGMSDVHAATGSPA-ELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQG 565
+ E L K + DV +T + A E + ++ G L+ K T+ + +
Sbjct: 23258 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23317
Query: 566 AVHKLIFPSMGPEHEGKYTFRAKG-------TESEASVFIAD---PPTIDPSVLEALAAH 615
V + S+ + + RA+ E+ +V + D PTID S + H
Sbjct: 23318 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIH 23377
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDS 675
V G + +P G+P P +W+ G ++ E ERV++E A LTI D+
Sbjct: 23378 ---VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 23434
Query: 676 GLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQ 735
G L+LKN G+ + T+ + +LD+P PP G ++ E+ + + + W+ P+ +GG P++
Sbjct: 23435 GEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSG 23494
Query: 736 FIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFA 795
++VE+R + W+ + E + T F ++ EG Y FR+ A N G+ L++E +
Sbjct: 23495 YVVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIEC 23553
Query: 796 GNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP 855
+ I PG Q+ DV+++ +T+TW P DGG+ V GYIVER++ ++ WV VNK P
Sbjct: 23554 RSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVP 23613
Query: 856 IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSS 915
+ T+ GL E EYE RV A+N G G+PS PS +VA DP+ PPG Q+ V+D++
Sbjct: 23614 VTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTT 23673
Query: 916 NSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFF 973
+S+SLAW P + G +GY++EM+ D EW+KC P YT+ L + +Y F
Sbjct: 23674 RTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRF 23733
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
R+ A N G GEP E+ V+ P ++L R + + VR G + + G P
Sbjct: 23734 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPF 23793
Query: 1034 PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVA 1093
P W K+G R I S+ H++ +I R DSG Y ++L+N+ G+ I VRV
Sbjct: 23794 PICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVI 23853
Query: 1094 DFPRPPTNLRLFEEVP-NTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERV 1149
P P ++++ +V ++W D DG A YI+ +R+ A WYT RV
Sbjct: 23854 GSPNSPEGPLEYDDIQVRSVRVSWRPPAD---DGGADILGYILERREVPKAAWYTIDSRV 23910
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
V GL +Y+FRV A N+ G S+PL S + P K
Sbjct: 23911 RGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE-----------------PVTPKTP 23953
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP------TVTLYKGDVNITANSKFWYNS 1263
+ P P P VL D T + L RP VT Y + T+ K+ ++
Sbjct: 23954 LNPPE--PPSNPPEVL---DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHN 24008
Query: 1264 TSGVCTLVIPTCTLKDSGDYS--VLVENELGKDRSS 1297
+ + T + L +Y ++ +N++G +S
Sbjct: 24009 KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETS 24044
Score = 377 bits (967), Expect = e-104
Identities = 245/766 (31%), Positives = 380/766 (49%), Gaps = 52/766 (6%)
Query: 448 TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIV 507
+L W K L+ T+Y + E L+ G + PTEY
Sbjct: 12763 SLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG-----SSPPSKPTEY------ 12811
Query: 508 TVEERLATVKSGMSDVHAATGSPAELCVVL----NDEKVEGVWLKDGKEITDLPGMQIVK 563
V R+ G +V T S L K+ G ++ E LPG + V+
Sbjct: 12812 -VTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFV----EACKLPGDKWVR 12866
Query: 564 -QGAVHKLI---FPSMGPEHEGKYTFRA----------KGTESEASVFIAD--PPTIDPS 607
A H++ + + G E + +Y FRA S+ +A+ PP ID S
Sbjct: 12867 CNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS 12926
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
V +TVK G + GKP+P V+W KDG + E + M + L +
Sbjct: 12927 VA---MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLEL 12983
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKD 727
+ R+DSG + +N GS +AT+ L VLD+P PP V+ ++ + W+ P +
Sbjct: 12984 FSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPAS-VKINKMYSDRAMLSWEPPLE 13042
Query: 728 NGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP 787
+GG +T +IV++R + +W ++ +T+ S K+ EG YQFRI A N GV DP
Sbjct: 13043 DGGSEITNYIVDKRETSRPNWAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDP 13101
Query: 788 LETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNL 847
+ TE A NP +PPG P ++++TK+ +T++W P DGG+P+ GY++E+R+ +
Sbjct: 13102 VFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVN 13161
Query: 848 WVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
W VN+ PI GL E TEYEFRV A+NKAGPG+PS S + A+DP PPG
Sbjct: 13162 WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPA 13221
Query: 908 DLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIP--ISGTCYTVG 963
V D++ SS+SL+W +PA G P GY++E++ D+ W +C +P + T + V
Sbjct: 13222 FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRC-NLPQNLQKTRFEVT 13280
Query: 964 GLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC 1023
GL+E +Y FR+ AVN+ G +P ++ P+ +L A L+ +++RAG +
Sbjct: 13281 GLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMR 13340
Query: 1024 IHAAFSGSPPPDVIWQKDGVPTKGRETI-TKSKNHSQFL-INSTKRSDSGVYRILLQNEF 1081
++ G PPP + W K V + R + KS + FL + + D+G Y + L+N
Sbjct: 13341 LYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSC 13400
Query: 1082 GEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDAST 1139
G+ Y I V+V D P PP N+ + E ++ +TW P + + G +Y++ KRDA
Sbjct: 13401 GKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTW--EPPIIDGGSPIINYVVQKRDAER 13458
Query: 1140 ATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+W T + V L G+ Y+FRV A NE G +P ++RD
Sbjct: 13459 KSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRD 13504
Score = 372 bits (954), Expect = e-102
Identities = 280/973 (28%), Positives = 457/973 (46%), Gaps = 72/973 (7%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRM 317
P + W+K EPL+ + +V++ T +L I N +D G Y++ S G
Sbjct: 17967 PRPNISWVKDGEPLK---QTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATE 18023
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVW--KFNGKELKRDDKYEI 375
+ + VL++P +G PV+ E +A F + +S + P + + + +++ D
Sbjct: 18024 NLSVIVLEKPGPPVG---PVRFDE-VSADFVV-ISWEPPAYTGGCQISNYIVEKRDTTTT 18078
Query: 376 T---VSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKA-----QLTIDRIPIK------- 420
T VS T+KI + +F A N K+ + I + P K
Sbjct: 18079 TWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGT 18138
Query: 421 -FVSNLKNVR--------VKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMN--H 468
FV+++ + V + + L K+ ++ W K + + TK+
Sbjct: 18139 PFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLD 18198
Query: 469 EGKRAELIIEDAQLSDGGEYT-----VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
EG E + + G+ + VA DP ++T K D
Sbjct: 18199 EGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYD- 18257
Query: 524 HAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVH--KLIFPSMGPEHEG 581
GS +V + +G W+K T++ + G V + F + G
Sbjct: 18258 ---GGSKITGYIVEKKDLPDGRWMK--ASFTNVLETEFTVSGLVEDQRYEFRVIARNAAG 18312
Query: 582 KYTFRAKGTESEASVFIADPP--TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKV 639
++ + + + + D P ++DP + + HA G T ++ RGKP+P V
Sbjct: 18313 NFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA-----GETFVLEADIRGKPIPDV 18367
Query: 640 TWYKDGMEVTEEE-RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVL 698
W KDG E+ E R+ ++ + L + +C+R D G +LKL N G+ + + + VL
Sbjct: 18368 VWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVL 18427
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
DRP PP+G ++ ++ ++ W P +GG ++ +I+E+R + SW ++ + +
Sbjct: 18428 DRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVS-TEVQA 18486
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAV 818
N+ K+ G Y FR++AVN G+ +PLE+ V A NP +PPG S P+V+ +TK+++
Sbjct: 18487 LNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSM 18546
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
+TW P DGG + GYI+E+R K W NK + + V GL E YEFRV A
Sbjct: 18547 VVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAA 18606
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYI 936
N AG G+PS PS A D + PPG + V+D+S SS+SLAW +P G P GY+
Sbjct: 18607 ENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYV 18666
Query: 937 LEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRA 995
+E++ EW+ CT + G +TV L E +Y FRI A+N GVGEP L V A
Sbjct: 18667 VEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVA 18726
Query: 996 MPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKGRETITKS 1054
P+ +L A L+ +V+RA L + G P P+V W+K +G+ T R I +
Sbjct: 18727 QERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT-DRAQIEVT 18785
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+ + +I++ R DSG Y + L+N G ++VRV D P P NL + E ++VTL
Sbjct: 18786 SSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTL 18845
Query: 1115 TWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVAR 1172
+W P + + G +YI+ KR+ + + T + + L G YYFRV+A
Sbjct: 18846 SW--EPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLAS 18903
Query: 1173 NEIGDSEPLDSRD 1185
NE G P ++ +
Sbjct: 18904 NEYGIGLPAETTE 18916
Score = 369 bits (946), Expect = e-101
Identities = 203/577 (35%), Positives = 321/577 (55%), Gaps = 11/577 (1%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ + G + ++ GKP P + WYKD E+ V +E D A + I + R +SG
Sbjct: 20510 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20569
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
LKL+N GSA+AT+ + +LD+P PP G +EF ++ + + W+ P D+GG +T +
Sbjct: 20570 CYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHY 20629
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
IVE+R + W + E + +T K+ +G Y FR+ AVN G+ +PLE++ V A
Sbjct: 20630 IVEKRETSRVVWSMVSEHLEECI-ITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAK 20688
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N PG P+VT +TK ++T+ W+ P DGG+ + GY +E+R K S W V K+ I
Sbjct: 20689 NAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETI 20748
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ T+ V GL E+++Y++RV AVN AG G S PS A DP+ PPG + ++DS+
Sbjct: 20749 RDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 20808
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSK-CTKIPISGTCYTVGGLIERQKYFF 973
SSI+L W +P G +GY++E+R + +EW+ TK + T Y V L Y+F
Sbjct: 20809 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 20868
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
R+ AVN AG GEP+E+++ V+A AP+ DL L++ ++ +AG + + F G PP
Sbjct: 20869 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPP 20928
Query: 1034 PDVIWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYD-IHV 1090
P V W+KD + + R +I + + S I R+D+G Y + ++N GE + + V
Sbjct: 20929 PTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSV 20988
Query: 1091 RVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAER 1148
+V D P L++ TVTL W+ P + + G +Y+I KRDA+ TW + +
Sbjct: 20989 KVLDTPAACQKLQVKHVSRGTVTLLWD--PPLIDGGSPIINYVIEKRDATKRTWSVVSHK 21046
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
S + + L ++FRV+A NEIG EP ++ +
Sbjct: 21047 CSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTE 21083
Score = 361 bits (927), Expect = 2e-99
Identities = 200/602 (33%), Positives = 315/602 (52%), Gaps = 12/602 (1%)
Query: 590 TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVT 649
+ES + + D +++ I VK G I G+PLP ++W KDG+E+
Sbjct: 19400 SESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE 19459
Query: 650 EEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVE 709
E R + ++ LLT+ +C+R D+G +L LKN G+ + ++ VLD+P PP G +E
Sbjct: 19460 ERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLE 19519
Query: 710 FLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEG 769
L+ + W P+++GG + +IVE+R +W I E + ++T+ K+ +G
Sbjct: 19520 INGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT-ICEGELQMTSCKVTKLLKG 19578
Query: 770 KAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDG 829
Y FR+ VN GV +PLE+ + A +P P + ++T VTKE++T+ W+ P DG
Sbjct: 19579 NEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDG 19638
Query: 830 GAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSV 889
G+ + GYI+ERR+K S WV VNK P+ + GL E EYE+RV A N AG PS
Sbjct: 19639 GSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSE 19698
Query: 890 PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEW 947
S + A+DPV P + DS ++I++AW +P G P +GY +E + D +W
Sbjct: 19699 TSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW 19758
Query: 948 SKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLS 1007
K + + GT YT+ GL +Y FR+++VN+ G +P + A P FD+
Sbjct: 19759 -KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDID 19817
Query: 1008 ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKR 1067
+ ++ ++V+AG + + F G P P+V+W K + R + + + + I + R
Sbjct: 19818 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANR 19877
Query: 1068 SDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQE-DG 1126
+DSG Y + +QN A + V+V D P PPTN+ + + + L+W DV E DG
Sbjct: 19878 NDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSW----DVPENDG 19933
Query: 1127 EA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
A +Y I KR+AS W + Y VT L G YYFRV NE G P ++
Sbjct: 19934 GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAET 19993
Query: 1184 RD 1185
++
Sbjct: 19994 KE 19995
Score = 358 bits (918), Expect = 2e-98
Identities = 222/650 (34%), Positives = 334/650 (51%), Gaps = 19/650 (2%)
Query: 552 EITDLPGMQIVKQGAVH--KLIFPSMGPEHEGKYTFR--AKGT--------ESEASVFIA 599
E DLP +K V+ + F GKY FR AK T ES ++
Sbjct: 13939 EKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICK 13998
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIK-VPFRGKPLPKVTWYKDGMEVTEEERVSMER 658
D VL+ +T+K G T + + GKPLPK +W K G ++ + +
Sbjct: 13999 DEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITS 14058
Query: 659 GEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCV 718
++LTI R+D+G + N G+ + ++VLD P PP G VE +S
Sbjct: 14059 TPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKA 14117
Query: 719 HMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILA 778
+ W P ++GG P+ +I+E+R + W + E D + K+ +G Y FR+ A
Sbjct: 14118 TLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSE-DIQSCRHVATKLIQGNEYIFRVSA 14176
Query: 779 VNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
VN G +P+++E V + PPG +P+V++VTK T++W P DGG+ + GY V
Sbjct: 14177 VNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14236
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
ERR+K S WV K P+ +C V GL E + YEFRV A N+AG G PS S SV+ KD
Sbjct: 14237 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14296
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPPSGYILEMRAEDTKEWSK-CTKIPI 955
PPG + HV+D++ S SLAW +P G +GY++E + + W K T +
Sbjct: 14297 AAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTAL 14356
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
T + V L ++KY FRI A+N+AGVGEP + V + AP F+L A L+ +V
Sbjct: 14357 RITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI-PDVEIVEREMAPDFELDAELRRTLV 14415
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
VRAG ++ I G P P+V W KD + K R I +++ + +I R D+G + +
Sbjct: 14416 VRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 14475
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
++N G+ ++VRV D P P NLR + ++VTL W+ +YI+ KR
Sbjct: 14476 TIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKR 14535
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+A+ ++ TA + Y VTGL G +Y+FRV+A NE G EP ++ +
Sbjct: 14536 EATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTE 14585
Score = 355 bits (910), Expect = 2e-97
Identities = 278/985 (28%), Positives = 444/985 (45%), Gaps = 97/985 (9%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P + W K PL+ + D + T L I + +D G Y ++V G K
Sbjct: 16885 PKPTITWTKDGLPLKQTTRINVTDSLDLTT---LSIKETHKDDGGQYGITVANVVGQKTA 16941
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKF---NGKELKRDDKYE 374
S E+ LD+P G PVK + + I LS P + N KRD
Sbjct: 16942 SIEIVTLDKPDPPKG---PVKFDD--VSAESITLSWNPPLYTGGCQITNYIVQKRDTTTT 16996
Query: 375 I--TVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV-QKAQLTIDRIPIKF---------- 421
+ VS TLK+ + +F A N Q L D I ++
Sbjct: 16997 VWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGT 17056
Query: 422 -----VSNLKNV-----RVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEG 470
+S V V + L K+ ++ W K + ++H T++ +
Sbjct: 17057 PFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQN-- 17114
Query: 471 KRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMS-DVHAATGS 529
L +G EY Y+ IV V + + ++ D G+
Sbjct: 17115 -----------LEEGIEYEF---------RVYAENIVGVGKASKNSECYVARDPCDPPGT 17154
Query: 530 PAELCVVLNDEKVEGVWLKD----GKEIT-------DLPGMQIVKQGAVHKLI--FPSMG 576
P + V N+ ++ W K G IT DLP + +K + + F G
Sbjct: 17155 PEPIMVKRNEITLQ--WTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSG 17212
Query: 577 PEHEGKYTFR----------AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAH 626
+ +Y FR +K ++S + D + ++ I V G T
Sbjct: 17213 LTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFR 17272
Query: 627 IKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDH 686
++ GKPLP + W + E+ E R ++ + +ALL + + +R D G +L+ N
Sbjct: 17273 LEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA 17332
Query: 687 GSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKK 746
GS + +++ VLDRP PP+G V+ ++ + W P +GG ++ ++VE+R +
Sbjct: 17333 GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRL 17392
Query: 747 SWIKIGEVDGKVTN-FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFA 805
+W + VTN K+ EG Y FRI+AVN GV +PLE+ V NP PG
Sbjct: 17393 AWTVVASE--VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPP 17450
Query: 806 SQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDG 865
+VT++ K+++T+ WN P DGG+ ++GYIVE+R + W+ NK I + V G
Sbjct: 17451 KSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTG 17510
Query: 866 LLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWRE 925
L ED EYEFRV A N AG G+PS + A DPV PG + H+ D++ +SI+LAW +
Sbjct: 17511 LTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGK 17570
Query: 926 PA--EGDPPSGYILEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAG 982
P G GY++E+ D +EW T + + T + + L E Q+Y R+ A+N+ G
Sbjct: 17571 PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVG 17630
Query: 983 VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG 1042
+GE + V+ AP+ DL + L+ +VVRAG + IH F G P P++ W ++
Sbjct: 17631 LGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREE 17690
Query: 1043 VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNL 1102
+ I K N++Q I++ R+D+G Y + L+N G + V+V D P PP NL
Sbjct: 17691 GEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNL 17750
Query: 1103 RLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLL 1160
+ E ++ L W P + + G +Y+I KR+++ + + + + V L
Sbjct: 17751 AVKEVRKDSAFLVW--EPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLT 17808
Query: 1161 PGRKYYFRVVARNEIGDSEPLDSRD 1185
G YYFRV+A NE G P+++ D
Sbjct: 17809 EGAIYYFRVMAENEFGVGVPVETVD 17833
Score = 352 bits (902), Expect = 2e-96
Identities = 208/628 (33%), Positives = 317/628 (50%), Gaps = 22/628 (3%)
Query: 580 EGK-YTFRA-------KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPF 631
EGK YTFR +GT SE +V D L+ L K +K+P
Sbjct: 13575 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13634
Query: 632 RGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATA 691
+GKP P V+W K + + RVS+E L + +C + D+G + LKN G+
Sbjct: 13635 KGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEG 13694
Query: 692 TLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKI 751
T+ + V+ +P P G ++F E++ + +KW PKD+GG +T +I+E+R W+
Sbjct: 13695 TISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTC 13754
Query: 752 GEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVT 811
K T F ++ EG Y FR+ A N GV + L++E + A +P + P P +
Sbjct: 13755 ASAVQKTT-FRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIV 13813
Query: 812 DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTE 871
DV ++V++TW P + GG+P+ GY +E +++ S LW NK PI+ V GL E E
Sbjct: 13814 DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLE 13873
Query: 872 YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EG 929
YEFRV+A+N AG G+PS+PS VVA DP+ PPG + +++ + +S++L W EP G
Sbjct: 13874 YEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINI---TRNSVTLIWTEPKYDGG 13930
Query: 930 DPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVE 988
+GYI+E R +K W K + + +TV L+E KY FRIRA N AG + P E
Sbjct: 13931 HKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSE 13990
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHA-AFSGSPPPDVIWQKDGVPTKG 1047
+ + AP L +K + ++AG + ++A + G P P W K G +
Sbjct: 13991 STETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRP 14050
Query: 1048 RE--TITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLF 1105
+ IT + S I R D+G Y I N FG + V V D P PP + +
Sbjct: 14051 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEIS 14110
Query: 1106 EEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGR 1163
TLTW +P +++ G YI+ KR+ S W +E + S ++ T L+ G
Sbjct: 14111 NVSAEKATLTW--TPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGN 14168
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINK 1191
+Y FRV A N G EP+ S ++++
Sbjct: 14169 EYIFRVSAVNHYGKGEPVQSEPVKMVDR 14196
Score = 352 bits (902), Expect = 2e-96
Identities = 217/667 (32%), Positives = 334/667 (50%), Gaps = 19/667 (2%)
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAV--HKLIFPSMGPEHEGKYTF 585
GS +V E EG W+K T++ G V H+ F + G ++
Sbjct: 16095 GSKITGYIVEKKELPEGRWMK--ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSE 16152
Query: 586 RAKGTESEASVFIADPPTI--DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYK 643
++ T + + DPP I DP + + HA G + + GKP+P + W K
Sbjct: 16153 PSESTGAITARDEVDPPRISMDPKYKDTIVVHA-----GESFKVDADIYGKPIPTIQWIK 16207
Query: 644 DGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKP 703
E++ R+ ++ + L++ + VR DSG +LK KN G + T+++ VLDRP P
Sbjct: 16208 GDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP 16267
Query: 704 PQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFST 763
P+G V ++ + WK P +GG + +IVERR + W + + + + +
Sbjct: 16268 PEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV-DANVQTLSCKV 16326
Query: 764 NKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWN 823
K+ EG Y FRI+AVN GV +PLE+E V A NP P P+VT VTK+++ + W
Sbjct: 16327 TKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWE 16386
Query: 824 APTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAG 883
P DGG+ +LGY++E+R K W +K I + V GL+E+ +YEFRV A N AG
Sbjct: 16387 RPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAG 16446
Query: 884 PGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRA 941
+PS PS+ A DP+ PG + V D + SS+ L+W +P G GYI+E
Sbjct: 16447 LSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCD 16506
Query: 942 EDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPA 1000
EW+ CT I+ T V L+E+ +Y FRI A+N+AGVGE ++ +
Sbjct: 16507 VSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLE 16566
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
AP DL L+ + +RAG +L + G P P+V W K + I + + +
Sbjct: 16567 APDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSL 16626
Query: 1061 LINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
++++ R DSG Y + L+N G + VRV D P PP NL++ E ++V++TW P
Sbjct: 16627 VLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW--EP 16684
Query: 1121 DVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+ + G +YI+ KR+A+ ++ N + + L G YYFRV A NE G
Sbjct: 16685 PLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG 16744
Query: 1179 EPLDSRD 1185
P + D
Sbjct: 16745 LPAQTAD 16751
Score = 351 bits (901), Expect = 2e-96
Identities = 205/589 (34%), Positives = 309/589 (52%), Gaps = 19/589 (3%)
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKD--GMEVTEEERVSMERGEDQALL 665
VL+ + +TVK G T ++ RGKP P+V W KD ++T RV ++ D +
Sbjct: 11830 VLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKF 11889
Query: 666 TISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAP 725
+++ R D G ++ N GS A ++VLD+P P + ++ +++S + W P
Sbjct: 11890 SLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRN-LKIVDVSSDRCTVCWDPP 11948
Query: 726 KDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVS 785
+D+GG + +I+E+ + W + ++ EG Y FR+ A N G
Sbjct: 11949 EDDGGCEIQNYILEKCETKRMVWSTYSATV-LTPGTTVTRLIEGNEYIFRVRAENKIGTG 12007
Query: 786 DPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGS 845
P E++ V A + PG P+VT V+KE +T+ WN P DGG + GY +E+++K S
Sbjct: 12008 PPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 12067
Query: 846 NLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL 905
WVPVNK I + V LL D EY+FRV A N+ G G+PS+PS VVAKDP++PPG
Sbjct: 12068 TRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGP 12127
Query: 906 VQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMR-----AEDTKEWSKC-TKIPISG 957
+ V D++ SI+L W +P G P GY++EMR A + W +C +
Sbjct: 12128 PTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVR 12187
Query: 958 TCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVR 1017
+TV L E Q+Y FR+ A N+ G+G P EL + ++ P+ DL A ++ ++VR
Sbjct: 12188 KEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVR 12247
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLI--NSTKRSDSGVYRI 1075
AG + + A G P P V W+K G+ R+ + FL+ NST R DSG Y +
Sbjct: 12248 AGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNST-RDDSGKYSL 12306
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIM 1133
L N GE ++VRV D P P ++L++ + + ++W +P + G HYI+
Sbjct: 12307 TLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSW--APPENDGGSQVTHYIVE 12364
Query: 1134 KRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
KR+A TW T V + VT L+PG +YYFRV A NE G P D
Sbjct: 12365 KREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTD 12413
Score = 348 bits (892), Expect = 3e-95
Identities = 218/651 (33%), Positives = 325/651 (49%), Gaps = 40/651 (6%)
Query: 581 GKYTFRAKGTES------EASVFIAD------PPTIDPSVLEALAAHAITVKVGHTAHIK 628
G+Y FR K + A+V D PP+ID + V+ G +I
Sbjct: 9713 GEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSID-------LKEFMEVEEGTNVNIV 9765
Query: 629 VPFRGKPLPKVTWYK------DGME-VTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
+G P P +TW+K D E V + V+ +D L I R D+GL +
Sbjct: 9766 AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTIT 9825
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
N+ G+A+ + L+VL RP PP G ++F +S + + W PKD+GG +T +++E+R
Sbjct: 9826 AVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKR 9885
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
+K+W+ + + K ++ K+ EG Y FRI+A N G+ +PL++E A N
Sbjct: 9886 EANRKTWVHVSS-EPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSV 9944
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQ---- 857
PG +P V+ VT+ ++T+ W P DGG+PV GY +E + S W VN+DPI+
Sbjct: 9945 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 10004
Query: 858 GTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNS 917
G V GL+E ++Y+FRV A+N AG G S+PS A+DP+ PPG V+D + S
Sbjct: 10005 GVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKS 10063
Query: 918 SISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRI 975
S L W P + G +GYI+E + E +EW K + GT V GL E Y FR+
Sbjct: 10064 SADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRV 10123
Query: 976 RAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD 1035
RAVN AG+GEP E+ + +P L A ++ +VV AG + I A SG PPP
Sbjct: 10124 RAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPT 10183
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADF 1095
V W + TI + S +I + +RS GVY +L +NE GE + I V V D
Sbjct: 10184 VTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDV 10243
Query: 1096 PRPPTNLRLFEEVPN-TVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKY 1154
P P L + N + LTW D +Y+I KR++ W V
Sbjct: 10244 PGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA 10303
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINK-----DQIQDLSAK 1200
TV GL+ G+ Y+FR+ A N IG +++ + +I + ++ +DL K
Sbjct: 10304 TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVK 10354
Score = 348 bits (892), Expect = 3e-95
Identities = 210/595 (35%), Positives = 309/595 (51%), Gaps = 17/595 (2%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
IA TI PS+ L + +++ G I++P G+P P ++W KDG + + RV++E
Sbjct: 17932 IAKDLTIQPSL--KLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE 17989
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSC 717
+L I ++D G + N G+AT L + VL++P PP G V F E+S
Sbjct: 17990 ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADF 18049
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
V + W+ P GG ++ +IVE+R +W + + T K++ G YQFRI
Sbjct: 18050 VVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT-IKITKLKTGTEYQFRIF 18108
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYI 837
A N G S PL+++ V P + PG P VT ++K+ + + W+ P DGG ++GY
Sbjct: 18109 AENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYH 18168
Query: 838 VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAK 897
+E+++K S LWV +NK PIQ TK GL E EYEF+V A N G G+PS S VA+
Sbjct: 18169 LEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVAR 18228
Query: 898 DPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPI 955
DP PPG + + + + ++++L W++PA G +GYI+E + W K + +
Sbjct: 18229 DPCDPPGRPEAIVI---TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 18285
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
T +TV GL+E Q+Y FR+ A N AG EP + + A AP L + K +
Sbjct: 18286 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVI 18345
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSG 1071
VV AG + A G P PDV+W KDG T R I + + ++ R+D G
Sbjct: 18346 VVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGG 18405
Query: 1072 VYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGE--A 1128
Y + L N G I V+V D P PP L++ L WN P +Q+ G +
Sbjct: 18406 QYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN--PPLQDGGANIS 18463
Query: 1129 HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
HYII KR+ S +W + V + Y VT LLPG +Y FRV+A N+ G EPL+S
Sbjct: 18464 HYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLES 18518
Score = 345 bits (885), Expect = 2e-94
Identities = 290/986 (29%), Positives = 433/986 (43%), Gaps = 117/986 (11%)
Query: 268 WIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEP 327
WIK T ++ + Q KY IS +N DAG VG+ + ++ +++
Sbjct: 14347 WIKDTTGTALRITQFVVPDLQTKEKYNFRISAIN--DAG-----VGEPAVIPDVEIVER- 14398
Query: 328 LKFLGEMKP---VKVTERQTAVFEIRLS---------KKEPNFVWKFNGKELKRDDKYEI 375
EM P + R+T V LS + P W + LK E
Sbjct: 14399 -----EMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIEN 14453
Query: 376 TVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSR 435
T S L I + D+G+F +TI+ P S NVRV +
Sbjct: 14454 TESFT----LLIIPECNRYDTGKFV-----------MTIEN-PAGKKSGFVNVRVLDTPG 14497
Query: 436 ACLEC---ELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRA--------------ELIIE 478
L ++T VTL W D L+ G++ + KR + +
Sbjct: 14498 PVLNLRPTDITKDSVTLHW--DLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 14555
Query: 479 DAQLSDGGEYTVVAMQD-----GDPTEYYSTAIVTVEERLATVKS-GMSDVHAAT----- 527
LS+G EY M + G+PTE +T V E + S + D+ +T
Sbjct: 14556 VTGLSEGCEYFFRVMAENEYGIGEPTE--TTEPVKASEAPSPPDSLNIMDITKSTVSLAW 14613
Query: 528 -------GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHE 580
GS V+ K W IT + G++ V + G E
Sbjct: 14614 PKPKHDGGSKITGYVIEAQRKGSDQWT----HITTVKGLECVVRNLTE-------GEE-- 14660
Query: 581 GKYTFRAKGTES-------EASVFIADPPTIDPSV-LEALAAHAITVKVGHTAHIKVPFR 632
YTF+ S E+ I T+ P + L + + K G +++P
Sbjct: 14661 --YTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVL 14718
Query: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
G+P P VTW K + + +RV+ E +L I+ CVR DSG L +N G
Sbjct: 14719 GRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDV 14778
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
+ + V D P PP G ++F E+S V W P+++GG P++ ++VE R +W+++
Sbjct: 14779 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELA 14838
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTD 812
+ T + ++ G YQFR+ A N GV + + + A P + PG PQVT
Sbjct: 14839 TTVIRTT-YKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14897
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
VTK+++TI+W+ P DGG+P+LGY VER+++ LW V+K + G GL + Y
Sbjct: 14898 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAY 14957
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGD 930
EFRVIA N AG +PS PS ++A DP+ PPG L++ + +++L W +P G
Sbjct: 14958 EFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNI---TRHTVTLKWAKPEYTGGF 15014
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVEL 989
+ YI+E R W K I +TV GL E Y FR+ A N AG + P E
Sbjct: 15015 KITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEP 15074
Query: 990 DKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE 1049
+ APK + + K ++++AG A + A SG PPP + W KDG +G
Sbjct: 15075 SDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTA 15134
Query: 1050 TI-TKSKNHSQFLIN-STKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFE 1106
+ K + S L+N + R DSG Y + N G A++ +V+V D P PP L + E
Sbjct: 15135 KLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTE 15194
Query: 1107 EVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRK 1164
L+W P + + G HYI+ KR+ S W A V K VT LL G +
Sbjct: 15195 VTSEKCVLSW--FPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNE 15252
Query: 1165 YYFRVVARNEIGDSEPLDSRDTWLIN 1190
Y FRV+A N+ G EPL+S +N
Sbjct: 15253 YIFRVMAVNKYGVGEPLESEPVLAVN 15278
Score = 341 bits (874), Expect = 3e-93
Identities = 190/575 (33%), Positives = 298/575 (51%), Gaps = 8/575 (1%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ +K G ++ G+P P + W KDG E+ ++ ++ + L + R DSG
Sbjct: 15099 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15158
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
L N G A ++ VLDRP PP+G + E++ + W P D+GG + +
Sbjct: 15159 AYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY 15218
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
IV++R + +W + + +VT K+ +G Y FR++AVN GV +PLE+E V A
Sbjct: 15219 IVQKRETSRLAWTNVAS-EVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAV 15277
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
NP PP P+VT +TK+++ + W P DGG+ ++ YIVERR K W+ NK +
Sbjct: 15278 NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTL 15337
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ V GL E EYEFR++A N AG PS S A D V PG + V D+S
Sbjct: 15338 TDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSR 15397
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFF 973
SSIS+AW +P G +GY++E+ + EW T + T YT+ GL E Q+Y
Sbjct: 15398 SSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKI 15457
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
RI A+N G+GEP + +A P+ +L A L+ + +RA L + G P
Sbjct: 15458 RIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPA 15517
Query: 1034 PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVA 1093
P+V W +D + + +I + +++ ++ + R DSG Y + ++N G ++VRV
Sbjct: 15518 PEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVL 15577
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFS 1151
D P PP +L++ E +VTLTW+ P + + G +YI+ KR+++ + T A
Sbjct: 15578 DTPGPPQDLKVKEVTKTSVTLTWD--PPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHK 15635
Query: 1152 NKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDT 1186
+ V L G YYFRV+A NE G P ++ ++
Sbjct: 15636 TSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAES 15670
Score = 340 bits (872), Expect = 5e-93
Identities = 197/589 (33%), Positives = 296/589 (50%), Gaps = 11/589 (1%)
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
PP+++ L+ + VK G T RG P+P W DG E+ +E ++E
Sbjct: 11135 PPSVE---LDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11191
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHM 720
++LTI NC+R D+G + + N GS T +HL+VLD P PP G + L+++ + +
Sbjct: 11192 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 11251
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W+ PKD+GG PV +IVE++ K +W + K T +++G Y FR+ A N
Sbjct: 11252 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-TKLKIPHLQKGCEYVFRVRAEN 11310
Query: 781 SEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVER 840
GV PL++ A + PP +P VTD+T+ A T++W P DGG+P+ GY +ER
Sbjct: 11311 KIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMER 11370
Query: 841 RKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPV 900
R+ + WV VNK PI K V GL E YEFRV A N AG +PS S + A P+
Sbjct: 11371 REV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPI 11429
Query: 901 KPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGT 958
KPPG + + D S + L W +P G P GY++E + T +W++ K +
Sbjct: 11430 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11489
Query: 959 C-YTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVR 1017
C + V GLIE +Y FRI+A N G GEP EL + V A P+ +L + + VR
Sbjct: 11490 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVR 11549
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
G + I A G P PD+ W K+G + + R + + + I R+D G Y I
Sbjct: 11550 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYII 11609
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
+N G A+ V V D P P NL++ T++W + D ++I+ R
Sbjct: 11610 SAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR 11669
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ W A V + + LL +YYFRV A N++G ++++
Sbjct: 11670 KPNQKGWSIVASDV-TKRLIKANLLANNEYYFRVCAENKVGVGPTIETK 11717
Score = 335 bits (859), Expect = 2e-91
Identities = 196/574 (34%), Positives = 306/574 (53%), Gaps = 14/574 (2%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE--DQALLTISNCVRED 674
+ +K G + IK +G+P+P+VTW+KDG+E+ E+R++ME + L + + R+
Sbjct: 21596 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEI--EKRMNMEITDVLGSTSLFVRDATRDH 21653
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
G+ ++ KN GSA A + + V D P G + F ++G + + W AP ++G P+T
Sbjct: 21654 RGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPIT 21713
Query: 735 QFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF 794
+I+E+R + +W I E + +++ K+ G YQFR+ AVN GV PL+++ V
Sbjct: 21714 HYIIEKRETSRLAWALI-EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVV 21772
Query: 795 AGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPV-NK 853
A P P+ +++T ++T+TW P DGG+ + YI+ERR+K S WV V +K
Sbjct: 21773 AQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISK 21832
Query: 854 DPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSD 913
PI T+ V GL E EYEF V+A N AG G S S + ++PV PPG + V+D
Sbjct: 21833 RPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTD 21892
Query: 914 SSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKY 971
+S +++SL W +P G GYI+EM D +W K T YTV L ++Y
Sbjct: 21893 TSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEY 21952
Query: 972 FFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGS 1031
FR+ A+N AG G+ E+ ++A+ AP+ D+ A K VVRAG ++ + A+ G
Sbjct: 21953 KFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGR 22012
Query: 1032 PPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091
P P +W K R I + + S + + R+D+G Y + ++N G V+
Sbjct: 22013 PTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVK 22072
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA---HYIIMKRDASTATWYTAAER 1148
V D P PP + + + TL W+ +P + DG A HY++ KR+AS +W +E+
Sbjct: 22073 VLDTPGPPGPITFKDVTRGSATLMWD-APLL--DGGARIHHYVVEKREASRRSWQVISEK 22129
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
+ V L G YYFRV A NE G EP +
Sbjct: 22130 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYE 22163
Score = 331 bits (849), Expect = 2e-90
Identities = 210/619 (33%), Positives = 310/619 (50%), Gaps = 26/619 (4%)
Query: 582 KYTFRAKGTESEASVFIADPPTIDPSVLEA---------LAAHAITVKVGHTAHIKVPFR 632
+Y+FR + I+DP + V+ L + TV G + VPF
Sbjct: 15744 EYSFRVSAQNEKG---ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFI 15800
Query: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
G+P P VTW+KD + + + RV+ E E+ +LLTI + RED G ++KL N G A T
Sbjct: 15801 GRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIET 15860
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
L++ VLD+P PP G V+ E++ + + W PK +GG + +IVE+R +W +
Sbjct: 15861 LNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15920
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTD 812
+ T +++ G YQFRI A N G S L +E A P + PG P VT
Sbjct: 15921 ATVARTT-IKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTL 15979
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
+++++ + WN P DGG+ V+GY +ER+++ S LWV +NK PI TK GL E EY
Sbjct: 15980 SSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEY 16039
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGD 930
EFRV A N G G+PS S VA+DP PPG + + V + +S++L W++P G
Sbjct: 16040 EFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIV---TRNSVTLQWKKPTYDGGS 16096
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV-GEPVEL 989
+GYI+E + W K + I T + V GL+E +Y FR+ A N AGV EP E
Sbjct: 16097 KITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSES 16156
Query: 990 DKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK--DGVPTKG 1047
+ A P+ + + K +VV AG + + A G P P + W K +
Sbjct: 16157 TGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTA 16216
Query: 1048 RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEE 1107
R I + + + R DSG Y + +N GE ++V+V D P PP +
Sbjct: 16217 RLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16276
Query: 1108 V-PNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRK 1164
V TL W P +Q+ G +YI+ +R+ S W V + VT LL G +
Sbjct: 16277 VTAEKCTLAW--KPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNE 16334
Query: 1165 YYFRVVARNEIGDSEPLDS 1183
Y FR++A N+ G EPL+S
Sbjct: 16335 YTFRIMAVNKYGVGEPLES 16353
Score = 331 bits (848), Expect = 3e-90
Identities = 261/933 (27%), Positives = 421/933 (45%), Gaps = 67/933 (7%)
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEI 349
G +Y+ + +VN A S S D +++ E +EPL + + + A F +
Sbjct: 19778 GAEYVFRVKSVNKVGASDPSDS-SDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTM 19834
Query: 350 RL---SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+ + PN +W +L+ + T S LT I++A +DSG+++ N+
Sbjct: 19835 TVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLT----IENANRNDSGKYTLTIQNV 19890
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRW---KKDGQLLMHGTK 463
+ A LT+ + N+ V++ +T + L W + DG +
Sbjct: 19891 LSAASLTLVVKVLDTPGPPTNITVQD---------VTKESAVLSWDVPENDGGAPVKNYH 19941
Query: 464 YSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERL---ATVKSGM 520
K+A + + + + Y V +Q+G YY E + A K G+
Sbjct: 19942 IEKREASKKAWVSVTNN--CNRLSYKVTNLQEG--AIYYFRVSGENEFGVGIPAETKEGV 19997
Query: 521 SDVHAATGSPAELCVV-LNDEKVEGVWLK---DGK--------EITDLPGMQIVKQGAVH 568
+ P +L V ++ + V WLK DG E + VK
Sbjct: 19998 K-ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAK 20056
Query: 569 KLIFPSMGPEHEGKYTFRA-----KGTESEASVFIA-------DPPTIDPSVLEALAAHA 616
G +Y FR G + + +PP ID ++ +H
Sbjct: 20057 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID---MKNFPSHT 20113
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ V+ G + +P GKPLPKVT +DG+ + R + E + + + V D+G
Sbjct: 20114 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20173
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
+ N G+ A +++ VLDRP PP G V +++ V +KW+ PK +GG VT +
Sbjct: 20174 RYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNY 20233
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
I+ +R W ++ + T K+ G+ YQFRI A N G+SD +++ V
Sbjct: 20234 ILLKRETSTAVWTEVSATVAR-TMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVK 20292
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
P PG S P VT+VT+E++T+ W+ P +GG+ V+GY +E + + S LW NK I
Sbjct: 20293 LPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI 20352
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ T V + YEFRV A N AG G+PS PS V+A D +PP +++ ++D S
Sbjct: 20353 RTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPP---RNVRITDISK 20409
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+S+SL+W++PA G +GYI+E R W+K + ++ T + + GL + +Y FR
Sbjct: 20410 NSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFR 20469
Query: 975 IRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
+ A N G + P E+ + + P DL + RAGT++ + A SG P
Sbjct: 20470 VFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPA 20529
Query: 1034 PDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091
P + W KD + T + + + + LI R +SG Y + L+N G A I V+
Sbjct: 20530 PTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQ 20589
Query: 1092 VADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF 1150
+ D P PP F+ V +TL W D HYI+ KR+ S W +E +
Sbjct: 20590 ILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLE 20649
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
T T ++ G +Y FRV A N+ G EPL+S
Sbjct: 20650 ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 20682
Score = 330 bits (846), Expect = 6e-90
Identities = 206/622 (33%), Positives = 309/622 (49%), Gaps = 19/622 (3%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
+K+G ++ ++ +GK +F K + + PPT+ + L T++V
Sbjct: 10409 LKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELA---PPTLHLDFRDKL-----TIRV 10460
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
G + + GKP PKV+W+KD +V E++R ++ L R DSG +
Sbjct: 10461 GEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVV 10520
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
++N GS ++V+DRP PP G V F E++ + + WK P D+GG +T +I+E++
Sbjct: 10521 VENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKK 10580
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
VGK W+ + K T +K+ EGK Y FRI A N G+SDPL ++ + A +
Sbjct: 10581 EVGKDVWMPVTSASAKTT-CKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRV 10639
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG-TK 860
P QP VT+VTK++ +TWN P DGG P+ YI+E+R+ S W V KDPI TK
Sbjct: 10640 PDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTK 10698
Query: 861 CTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSIS 920
V LLE +YEFRV A N+ G G PS PS V AKDP+ P + D++ +S+
Sbjct: 10699 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10758
Query: 921 LAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPIS--GTCYTVGGLIERQKYFFRIR 976
L W+ P G GYI+E + +EW + P S T Y V GL + Q Y FR+
Sbjct: 10759 LTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVL 10818
Query: 977 AVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
AVN AG +P + + V P+ L A + ++ G L + A G P P V
Sbjct: 10819 AVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKV 10878
Query: 1037 IWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVAD 1094
W+K+ PTK R +T S+ I + D G+Y + ++N G + V V D
Sbjct: 10879 TWKKEDRDAPTKARIDVTPV--GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD 10936
Query: 1095 FPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKY 1154
P PP +L + E ++ LTW D +Y++ +RD ++A W + +
Sbjct: 10937 KPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSH 10996
Query: 1155 TVTGLLPGRKYYFRVVARNEIG 1176
L G +Y FRV A N+ G
Sbjct: 10997 FAKHLNEGNQYLFRVAAENQYG 11018
Score = 326 bits (836), Expect = 8e-89
Identities = 262/890 (29%), Positives = 401/890 (45%), Gaps = 86/890 (9%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQ 411
P VW EL DK + + G L IKDA D G + A G+ A+
Sbjct: 8762 PTKVWTKEEGEL---DKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAAR 8818
Query: 412 LTIDRIPIKFVSNLKNVRVKERSRACLECELTSKD----VT--LRWKKDGQLLMHGTKYS 465
+ + +P V +LK V V R L D +T + +KD + MH +
Sbjct: 8819 VEVFDVPGP-VLDLKPV-VTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQP 8874
Query: 466 MNHEGKRAELIIEDAQLSDGGEYT--VVAMQD---GDPTEYYSTAIV------TVEERLA 514
+ E + ++ L +G EY V+A G P E V T ERL
Sbjct: 8875 IETERSKCDI----TGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLT 8930
Query: 515 TVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPS 574
+ S + P ++G ++ K D P + V + F
Sbjct: 8931 YTERTKSTITLDWKEPRSN----GGSPIQGYIIE--KRRHDKPDFERVNKRLCPTTSFLV 8984
Query: 575 MGPEHEGKYTFRAKGT----ESEAS----VFIAD---PPTIDPSVLEALAAHAITVKVGH 623
+ Y FR K ESE S V I D PPTI + ++ I VK G
Sbjct: 8985 ENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRL--SVRGDTIKVKAGE 9042
Query: 624 TAHIKVPFRGKPLPKVTWYK---------DGMEVTEEERVSMERGEDQALLTISNCVRED 674
HI G P+PK+ W K D +++T+EE + R E + L+I VRED
Sbjct: 9043 PVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEE---VSRSEAKTELSIPKAVRED 9099
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
G + N GS +H+ V DRP PP+ + ++ ++ W AP DNGG +T
Sbjct: 9100 KGTYTVTASNRLGSVFRNVHVEVYDRPSPPRN-LAVTDIKAESCYLTWDAPLDNGGSEIT 9158
Query: 735 QFIVERRAVGKKS--WIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE 792
+++++R +K W ++ + + K+ Y+FR+ AVN G+SD ++++
Sbjct: 9159 HYVIDKRDASRKKAEWEEVTNTAVE-KRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDK 9217
Query: 793 VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW---- 848
V +P PG +P+V TK ++ ++W P +GG+P+ GY +E+R++GS W
Sbjct: 9218 VVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVS 9277
Query: 849 -VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
P+ K ++G + V LLE +Y+FR +A+N AG G PS PS VA DP+ PPG
Sbjct: 9278 RAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPS 9337
Query: 908 DLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTK-IPISGTC-YTVG 963
V D + SSISL W+ PA+ G P GYI+EM+ E T +W + + + TC V
Sbjct: 9338 CPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVP 9397
Query: 964 GLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC 1023
L E +KY FR++AVNEAG EP + + A P+ + + +V +AG+ +
Sbjct: 9398 NLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIR 9457
Query: 1024 IHAAFSGSPPPDVIWQKDGVPTKGRE----------TITKSKNHSQFLINSTKRSDSGVY 1073
I A G P P W+ DG K + + ++N S +I KRS +G Y
Sbjct: 9458 IPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKY 9517
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM 1133
I +N+ G+ + V+V D P PP +L++ + + L+W D D Y+I
Sbjct: 9518 SITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIE 9577
Query: 1134 KRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
KR W S + V LL ++Y+FRV A N G P+++
Sbjct: 9578 KRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVET 9627
Score = 326 bits (836), Expect = 8e-89
Identities = 217/659 (32%), Positives = 323/659 (49%), Gaps = 43/659 (6%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGT---------ESEASVFIADPPTIDPSVLEAL 612
V+ G +L F + +Y FR K E+ +SV I +P + L +
Sbjct: 22221 VEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGI 22280
Query: 613 AAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVR 672
IT K G I VP G+P PKVTW + M + E +RVS+ +D+ LT+ + +R
Sbjct: 22281 TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMR 22340
Query: 673 EDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRP 732
DSG L L+N G T ++ + V+ RP P G +E +S + W PKD GG
Sbjct: 22341 GDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22400
Query: 733 VTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE 792
+T +IVE+R G +W + K T + + Y FR+ + N GVS PLE+
Sbjct: 22401 ITNYIVEKRESGTTAWQLVNS-SVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAP 22459
Query: 793 VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN 852
+ A +P PP ++P+V V+ A++I W P DGG+ ++GY VE++++ + LWV N
Sbjct: 22460 IIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKEN 22519
Query: 853 KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVS 912
K P V GL+E EY+FR A+N AG + S S ++A++PV PG + V+
Sbjct: 22520 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE---VT 22576
Query: 913 DSSNSSISLAWREPA--EGDPPSGYILEMRAED---TKEWSKCTKIPISGTCYTVGGLIE 967
D + S++SL W PA G GYI+E + W KC +S +TV L E
Sbjct: 22577 DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE 22636
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP------AAPKFDLSARLKSHMV-VRAGT 1020
Y FR+ A N AGV + KG + P A PK +L ARL +V +RAG+
Sbjct: 22637 GDTYEFRVLAKNAAGV-----ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGS 22691
Query: 1021 ALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
L + AA G P P +IW K + + ++ + + +I RSDSG Y + ++
Sbjct: 22692 DLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK 22751
Query: 1079 NEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA---HYIIMKR 1135
N G + V+V D P P L + TL W+ QEDG A HYI+ +R
Sbjct: 22752 NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLP---QEDGGAEITHYIVERR 22808
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIG-----DSEPLDSRDTWLI 1189
+ S W + Y VT L+ +Y FRV A N+ G +SEP+ +R+++ I
Sbjct: 22809 ETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTI 22867
Score = 325 bits (833), Expect = 2e-88
Identities = 227/759 (29%), Positives = 365/759 (48%), Gaps = 54/759 (7%)
Query: 587 AKGTESEASVFIADPPTIDPSVLEA-LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+KG+ES V D + L+A L +T++ G + GKP PK+ W K
Sbjct: 22654 SKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22713
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
E+ E+VS++ +A I C R DSG L +KN G+ ++ + VLD P P
Sbjct: 22714 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPC- 22772
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNK 765
G++ ++ + W P+++GG +T +IVERR + +W+ I E + ++ +
Sbjct: 22773 GKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWV-IVEGECPTLSYVVTR 22831
Query: 766 VEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
+ + Y FR+ AVN G P+E+E + A N P P+ KE + I W P
Sbjct: 22832 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 22891
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKD-PIQGTKCTVDGLLEDTEYEFRVIAVNKAGP 884
DGG + Y+V++R+K S W VNKD + T+ V L+E +Y+FRV AVN AG
Sbjct: 22892 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 22951
Query: 885 GQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAE 942
+PS S+ + ++P PG V D++ SISLAW +P G GY+LEM+ +
Sbjct: 22952 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 23011
Query: 943 DTKEWSKC-TKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAA 1001
DT +W + T I T +TV L QKY FR+ AVN G+ E E + +
Sbjct: 23012 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 23071
Query: 1002 PKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
P +L+ LK + +RAG +L + + SG PPP + W K G+ R I ++++S +
Sbjct: 23072 PDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI 23131
Query: 1062 INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
++ R D+G Y I +N+ G+ + V+V D P P ++++ E ++VT+TW P
Sbjct: 23132 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITW-EIPT 23190
Query: 1122 VQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+ DG A +YI+ KR+A+ + T + Y ++GL+ G YYFRV+ N G
Sbjct: 23191 I--DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23248
Query: 1179 EPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLG 1238
EP ++ D L+++ PL P L D T + L
Sbjct: 23249 EPCETSDAVLVSE-------------------------VPLVP-AKLEVVDVTKSTVTLA 23282
Query: 1239 NPRPTVTLYKGDVNIT--------ANSKFWYNSTSGVCTLVIPTCTLKDSGD---YSVLV 1287
+P LY G +T A ++ W + T++ T T + G+ + +
Sbjct: 23283 WEKP---LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRA 23339
Query: 1288 ENELGKDRSSCTLTVYDKDDKSVVASI-TESLQKKSKHL 1325
+NE G T+T D V+ +I ++ +K+ H+
Sbjct: 23340 QNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHV 23378
Score = 325 bits (832), Expect = 2e-88
Identities = 195/607 (32%), Positives = 305/607 (50%), Gaps = 16/607 (2%)
Query: 592 SEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE 651
S A +A I+P V A ++++ V+VG I+VP G+P P +TW KDG+ + +
Sbjct: 16844 SLAVPIVAKDLVIEPDVKPAFSSYS--VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQT 16901
Query: 652 ERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFL 711
R+++ D L+I ++D G + + N G TA++ + LD+P PP+G V+F
Sbjct: 16902 TRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFD 16961
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKA 771
++S + + W P GG +T +IV++R W + + T K++ G
Sbjct: 16962 DVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT-LKVTKLKTGTE 17020
Query: 772 YQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA 831
YQFRI A N G S LE++ + A P + PG P T ++K+++ I W+ P +GG+
Sbjct: 17021 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 17080
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
PV+GY +ER+++ S LW VNK I T+ L E EYEFRV A N G G+ S S
Sbjct: 17081 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 17140
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSK 949
VA+DP PPG + + V + I+L W +P G +GYI+E R W K
Sbjct: 17141 ECYVARDPCDPPGTPEPIMV---KRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMK 17197
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSA 1008
+ + T +TV GL E Q+Y FR+ A N AG + +P + + A P+ +
Sbjct: 17198 ASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP 17257
Query: 1009 RLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTK 1066
+ + +VV AG + A G P P + W + + R I + + ++
Sbjct: 17258 KFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAI 17317
Query: 1067 RSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQED 1125
R D G Y + N G + ++V+V D P PP +++ +LTW SP +Q+
Sbjct: 17318 RIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW--SPPLQDG 17375
Query: 1126 GE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
G +HY++ KR+ S W A V +N VT LL G +Y FR++A N+ G EPL+S
Sbjct: 17376 GSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLES 17435
Query: 1184 RDTWLIN 1190
+ N
Sbjct: 17436 APVLMKN 17442
Score = 318 bits (816), Expect = 2e-86
Identities = 196/641 (30%), Positives = 304/641 (47%), Gaps = 25/641 (3%)
Query: 557 PGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEA--------SVFIADPPTIDPSV 608
P + + V L G + KY FR + V+ A + P +
Sbjct: 12471 PADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI 12530
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L IT+K G I+ GKP P W K EV +++ + + ++L I
Sbjct: 12531 L---MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 12587
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
+ R+DSG L +N G+ T + + V+D P PPQ + ++ + W P ++
Sbjct: 12588 DVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLED 12647
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG +T +IVE+ V + W+ K T+ K+ G+ Y FR+ A N G+S+PL
Sbjct: 12648 GGSNITNYIVEKCDVSRGDWVTALASVTK-TSCRVGKLIPGQEYIFRVRAENRFGISEPL 12706
Query: 789 ETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW 848
+ ++ A P P +VT V K+ + + W+ P DGG+P++GY++ER+++ S LW
Sbjct: 12707 TSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLW 12766
Query: 849 VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQD 908
V N ++ T+ GL+E EY FR+ A+NKAG PS P+ V A+ PV PPG +
Sbjct: 12767 VKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPE- 12825
Query: 909 LHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIP--ISGTCYTVGG 964
V D + S++SL W P G GY +E +W +C P I YT G
Sbjct: 12826 --VIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATG 12883
Query: 965 LIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCI 1024
L E+ +Y FR A + P E V + P+ DLS +KS + V+AGT +C+
Sbjct: 12884 LEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 12943
Query: 1025 HAAFSGSPPPDVIWQKDGVPTKGRETI--TKSKNHSQFLINSTKRSDSGVYRILLQNEFG 1082
A G P P V W+KDG K E I +N + S R DSG Y I +N G
Sbjct: 12944 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 13003
Query: 1083 EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTA 1140
I ++V D P PP ++++ + + L+W P +++ G +YI+ KR+ S
Sbjct: 13004 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSW--EPPLEDGGSEITNYIVDKRETSRP 13061
Query: 1141 TWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPL 1181
W + V +V L+ G +Y FR+ A N+ G +P+
Sbjct: 13062 NWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPV 13102
Score = 317 bits (812), Expect = 5e-86
Identities = 193/605 (31%), Positives = 291/605 (48%), Gaps = 26/605 (4%)
Query: 598 IADPPTIDPSVLEALA-----------AHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
++DP TI P ++ L +TV++GH H+++P++GKP P ++W KDG+
Sbjct: 21171 LSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGL 21230
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
+ E E V + E++ L+I N +E G + L N + + L P P+G
Sbjct: 21231 PLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKG 21290
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
+ F E+ V + W P+DNGG +T + +E+R + +W + + T N V
Sbjct: 21291 PIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLV 21350
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
++ + YQFR+ A N GVS PL + + A + PG +P + +VT + +++TW+AP
Sbjct: 21351 KDAE-YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPV 21409
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQ 886
DGG+ V G+ VE++++ S LW VN PI G + GL+E +Y+FRV A N AG
Sbjct: 21410 YDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSS 21469
Query: 887 PSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDT 944
PS PS +A PV PPG + D + +I+L W P G GY +E R +
Sbjct: 21470 PSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKR-QGN 21525
Query: 945 KEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG-VRAMPPPAAPK 1003
+ W +C +S YTV GL +Y FRI A N G P G + P
Sbjct: 21526 ERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPI 21585
Query: 1004 FDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRET--ITKSKNHSQFL 1061
+ +++++G +L I A G P P V W KDGV + R IT +
Sbjct: 21586 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 21645
Query: 1062 INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+ R GVY + +N G A+ +I V+V D P F + W +P
Sbjct: 21646 VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAP- 21704
Query: 1122 VQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
DG A HYII KR+ S W ++ + YT L+ G +Y FRV A N+ G
Sbjct: 21705 -LNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 21763
Query: 1179 EPLDS 1183
PLDS
Sbjct: 21764 RPLDS 21768
Score = 313 bits (801), Expect = 9e-85
Identities = 262/892 (29%), Positives = 399/892 (44%), Gaps = 90/892 (10%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTID 415
P W +GKE+K D+ +T+ D ++ L++ + +D+G ++ N + A +I+
Sbjct: 8044 PTVSWHKDGKEVKASDR--LTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 8101
Query: 416 RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAEL 475
I K+++ + +++ C+LT + DG + G+R +
Sbjct: 8102 VKVIGLPGPCKDIKASDITKS--SCKLTWEPPEF----DGGTPILHYVLERREAGRRTYI 8155
Query: 476 IIEDAQ---------LSDGGEY--TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524
+ + L GEY V A+ EY + + DV
Sbjct: 8156 PVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8215
Query: 525 AATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVK---------QGAVHKLIFPSM 575
+ + + +G G +I +I K + V L + +
Sbjct: 8216 VHNPTAEAMTITWKPPLYDG-----GSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAK 8270
Query: 576 GPEHEGKYTFRAKGTESEASVFI---ADPPT--IDP-SVLEALAAHAITVKVGHTAHIKV 629
G E +Y FR + E+ A + A PPT +DP + + ++ VK G +
Sbjct: 8271 GLEEGKEYQFRVRA-ENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDA 8329
Query: 630 PFRGKPLPKVTWYKDGM--------------------EVTEEE--------RVSME---R 658
G P P +TW KD EV EEE R+S++ +
Sbjct: 8330 SISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKK 8389
Query: 659 GEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCV 718
GE Q L + + +R D GL ++K++NDHG A A +SVLD P PP V F ++ + V
Sbjct: 8390 GESQ--LRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFV-FEDIRKTSV 8446
Query: 719 HMKWKAPKDNGGRPVTQFIVERRAVGK--KSWIKIGEVDGKVTNFSTNKVEEGKAYQFRI 776
KW+ P D+GG + + +E++ K WI + + +S K+ EGK Y FR+
Sbjct: 8447 LCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTL-RHCKYSVTKLIEGKEYLFRV 8505
Query: 777 LAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGY 836
A N G P ++ + A +P PP +P V DVT ++ + WN P +D G+P+LGY
Sbjct: 8506 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEP-KDNGSPILGY 8564
Query: 837 IVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVA 896
+E+R+ S W VNK + K VDGLLE Y FRV A N AGPG+ S PS A
Sbjct: 8565 WLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTA 8624
Query: 897 KDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIP 954
DP+ PPG V+D+S+++I L W PA G GY ++ + T EWS+CT+
Sbjct: 8625 HDPISPPG-PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 8683
Query: 955 ISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
I YTV + E Y R+ AVN AG G P E + V P P +L +K +
Sbjct: 8684 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE-TQPVTVAEPQEPPAVELDVSVKGGI 8742
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
+ AG L I A +G P P +W K +G K R I S+ +I R D G Y
Sbjct: 8743 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 8802
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---Y 1130
I N G V V D P P +L+ L W+ D ++DG + +
Sbjct: 8803 VITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWS---DPEDDGGSEITGF 8859
Query: 1131 IIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
II ++DA TW E S K +TGLL G++Y FRV+A+N+ G P++
Sbjct: 8860 IIERKDAKMHTWRQPIETERS-KCDITGLLEGQEYKFRVIAKNKFGCGPPVE 8910
Score = 308 bits (790), Expect = 2e-83
Identities = 202/595 (33%), Positives = 288/595 (48%), Gaps = 19/595 (3%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
IA I PSV L H VK I VPF+G+P V W KDG + E RV++
Sbjct: 19015 IARDIEIKPSV--ELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVS 19072
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSC 717
+ L+I +ED G L + N GS T + + VLDRP PP G + E+S
Sbjct: 19073 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDS 19131
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
+ + W P+ +GG ++ +IVE++ +W + + + T+ ++ G YQFR+
Sbjct: 19132 ITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVAR-TSIKIVRLTTGSEYQFRVC 19190
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYI 837
A N G S E+ V A P PPG P+V TK + +TW P DGG+ V+GY
Sbjct: 19191 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 19250
Query: 838 VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAK 897
+E +++ S LW NK I T+ V GL E YE+RV A N AG G+ S V A+
Sbjct: 19251 LEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPAR 19310
Query: 898 DPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPPSGYILEMRAEDTKEWSKCTKIPI 955
DP PPG + V++ + S+SL W +P G +GYI+E R W KC I
Sbjct: 19311 DPCDPPGQPE---VTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNI 19367
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEA-GVGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
T + V L E Q+Y FR+ A N A V EP E + P+ + + + +
Sbjct: 19368 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVI 19427
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGV 1072
VV+AG L I+A +G P P + W KDG + + R I + NH+ + R D+G
Sbjct: 19428 VVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQ 19487
Query: 1073 YRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGEA--- 1128
Y + L+N G ++ +V D P PP L + +L+W QEDG A
Sbjct: 19488 YVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRP---QEDGGADID 19544
Query: 1129 HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+YI+ KR+ S W + VT LL G +Y FRV N+ G EPL+S
Sbjct: 19545 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLES 19599
Score = 293 bits (751), Expect = 6e-79
Identities = 187/608 (30%), Positives = 301/608 (49%), Gaps = 25/608 (4%)
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
++ TE +V + P I L+ +TVK G + GKP PK+TW K M
Sbjct: 7301 SRPTEEIQAVDTQEAPEI---FLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM 7357
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
+ +++R+++E ++ +TI + R D+G +++ N G ATA + ++VLD+P PP
Sbjct: 7358 ILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAA 7417
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
+ +++ + W P+D+GG +T ++VERRA + W K+ K TNF K+
Sbjct: 7418 -FDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTV-KDTNFKATKL 7475
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
K Y FR+ A N GV +P++ + A +PPG ++ + +D+TK+AVT+TW P
Sbjct: 7476 IPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPD 7535
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQ 886
DGG+P+ GY VER ++ WV NK P++ T V GL +Y FRV+A N AGPG+
Sbjct: 7536 DDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGK 7595
Query: 887 PSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDT 944
PS + ++ KDP+ PP V D +S+ L W +P G Y++EM T
Sbjct: 7596 PSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGT 7655
Query: 945 KEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV---RAMPPPAA 1001
EW + + + T + + GL+E Q+Y FR+RAVN+AG EP E V + PP+
Sbjct: 7656 DEWVRVAE-GVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSP 7714
Query: 1002 PKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
P++ + + A + GSP + I +K V KG +T+ + ++
Sbjct: 7715 PRWLEVINITKN---TADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7771
Query: 1062 INSTKRSDSGVYRILLQNEFGEARY---DIHVRVAD---FPRPPTNLRLFEEVPNTVTLT 1115
+ V+R+ +N G++ Y + V D P PP L + + V L
Sbjct: 7772 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLK 7831
Query: 1116 WNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSN-KYTVTGLLPGRKYYFRVVAR 1172
W P + G Y+I K++ W A + + + VT ++ G + F+V A
Sbjct: 7832 W--EPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAE 7889
Query: 1173 NEIGDSEP 1180
NE G P
Sbjct: 7890 NEAGVGHP 7897
Score = 285 bits (729), Expect = 2e-76
Identities = 315/1307 (24%), Positives = 527/1307 (40%), Gaps = 123/1307 (9%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
EF+ KPQ + EG+KA F + + P + WKR+ ++ K + K+ VL +
Sbjct: 6181 EFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKT-LESGDKYDVIADGKKRVLVV 6238
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTV-----------SLLVTEGQEKM-------DFKKM 169
+ T D Y + A A TV V E QE + + K
Sbjct: 6239 KDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKA 6298
Query: 170 LKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKV 229
R A K + +K+++ L ++ T+ RG K V
Sbjct: 6299 KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVK-SAANLIV 6357
Query: 230 EVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPL----RIQYSLGKYD 285
E E +RI++PL+D ET +V F C ++ NV + W K E + R+ Y + KY
Sbjct: 6358 EEEDLRIVEPLKDIETMEKKSVTFWC--KVNRLNVTLKWTKNGEEVPFDNRVSYRVDKY- 6414
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
K+ML I + D G Y ++ G + AEL +++ P +F+ ++ VTE A
Sbjct: 6415 ------KHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDA 6468
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
VF +LS+++ N W NG+E+K KY+ +DG H L IKD RL D E++ +
Sbjct: 6469 VFSCQLSREKANVKWYRNGREIKEGKKYKF--EKDGSIHRLIIKDCRLDDECEYACGVED 6526
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
+A+L ++ IP++ + +++ + EL V ++W ++ +++ G K+
Sbjct: 6527 RKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQ 6586
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
M EGK L I D + D GEY +A +D + A +K+ D+
Sbjct: 6587 MMSEGKIHRLQICDIKPRDQGEYRFIA-KDKEARAKLELAAAP------KIKTADQDLVV 6639
Query: 526 ATGSPAELCVVLND-EKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
G P + V + K E W K+ + ++ + + +++ G + K
Sbjct: 6640 DVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT-IDTTAEQTSFRILEAKKGDKGRYKIV 6698
Query: 585 FRAKGTESEA----SVFIADPPTIDPSVLEAL-----AAHAITVKVGHTAHIKVPFRGKP 635
+ K ++E V P + V E A + G + I +
Sbjct: 6699 LQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRD 6758
Query: 636 LPKVTWY--KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
+ + TW D E E +++G + L +S R +G ++ D+ +
Sbjct: 6759 IKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE---PVETDNPVEARSK 6815
Query: 694 HLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGE 753
+ D P PP V +++ V + W+ P+ +GG +T +++E R W
Sbjct: 6816 Y----DVPGPPLN-VTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMT 6870
Query: 754 VDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP-LETEEVFAGNPIEPPGFASQPQVTD 812
V + + + V EG+ Y FR+ A N GV P T V +PIE P +D
Sbjct: 6871 VRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSD 6930
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
T+ +V + W P +DGG+P+LGYI+ER ++G + W+ N + V GL + +Y
Sbjct: 6931 QTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKY 6990
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPP 932
+RV A NKAG PS + A D P + DL + + + P P
Sbjct: 6991 LYRVSAENKAGVSDPSEILGPLTADDAFVEPTM--DL---SAFKDGLEVIVPNPITILVP 7045
Query: 933 S-GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDK 991
S GY T W K+ +G +R K + A E + DK
Sbjct: 7046 STGY-----PRPTATWCFGDKVLETG---------DRVK-MKTLSAYAELVISPSERSDK 7090
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAG----------TALCIHAAFS------GSPPPD 1035
G+ + K +S + +++ R T +H + GSP
Sbjct: 7091 GIYTLKLENRVK-TISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTG 7149
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGE---ARYDIHVRV 1092
+ +K V K + +F + + ++++ +N+ G A D V +
Sbjct: 7150 YVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNM 7209
Query: 1093 ---ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERV 1149
A P PP N++ + N++ LTW+ + YI+ + + W E V
Sbjct: 7210 STPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPV 7269
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
K VTGL G+ Y +RV A N G S+P SR T ++IQ + + P D
Sbjct: 7270 AETKMEVTGLEEGKWYAYRVKALNRQGASKP--SRPT-----EEIQAVDTQEAPEIFLD- 7321
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
V L TV G + G P P +T K D+ + + + + T
Sbjct: 7322 ------VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST 7375
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
+ I D+G Y + N G+ + + V DK IT+
Sbjct: 7376 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITD 7422
Score = 273 bits (699), Expect = 6e-73
Identities = 160/493 (32%), Positives = 252/493 (51%), Gaps = 15/493 (3%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ +E + ++ + +KW P+ +GG P+T +IVE+R V +K W + + K T
Sbjct: 7712 PSPPRW-LEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV-DTTVKDTK 7769
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVT 819
+ + EG Y FR+ A N+ G SD E E+ V A + PG V DVTK V
Sbjct: 7770 CTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVD 7829
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAV 879
+ W P DGG P+ Y++E++++ WV K V ++E TE +F+V A
Sbjct: 7830 LKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAE 7889
Query: 880 NKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYIL 937
N+AG G PS P+ + +DP PP DLHV+D+ I++AW+ P + G P GY +
Sbjct: 7890 NEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHV 7949
Query: 938 EMRAEDTKEWSKCTKIPISGTCYTV-GGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
EM T++W + PI + V G++ ++Y R+RAVN GV EP E+ + V A
Sbjct: 7950 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 8009
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKN 1056
P P DL ++V G L I F P P V W KDG K + +T +
Sbjct: 8010 DPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKND 8066
Query: 1057 H--SQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
H + + + R+D+G+Y I L+N+ G A I+V+V P P +++ + ++ L
Sbjct: 8067 HISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKL 8126
Query: 1115 TWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVAR 1172
TW P + G HY++ +R+A T+ +TV L+P +Y+FRV A
Sbjct: 8127 TW--EPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 8184
Query: 1173 NEIGDSEPLDSRD 1185
N++G E ++ ++
Sbjct: 8185 NKVGGGEYIELKN 8197
Score = 255 bits (652), Expect = 2e-67
Identities = 168/569 (29%), Positives = 270/569 (47%), Gaps = 36/569 (6%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
I V+ G + +P +GKP P W K+G ++++ R + E L I R DSG
Sbjct: 23774 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK--RAMIATSETHTELVIKEADRGDSG 23831
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
L L+N G + + V+ P P+G +E+ ++ V + W+ P D+GG + +
Sbjct: 23832 TYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGY 23891
Query: 737 IVERRAVGKKSWIKIGEVDGKV--TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF 794
I+ERR V K +W I D +V T+ ++E Y FR+ A N G+S PL++EE
Sbjct: 23892 ILERREVPKAAWYTI---DSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 23948
Query: 795 AG----NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP 850
NP EPP ++ P+V DVTK +V+++W+ P DGG+ V GY +ER++ ++ WV
Sbjct: 23949 TPKTPLNPPEPP--SNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24006
Query: 851 VNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLH 910
NK I T TV GL+ D EY+FR+IA N G + S S VV KDP P +L
Sbjct: 24007 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24066
Query: 911 VSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ S S++L W +P G GY +E R W K K I +T+GGL+E
Sbjct: 24067 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24126
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRA-MPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
+Y FR+ A NE G+ P ++ + AP + +K + + G A +
Sbjct: 24127 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAP--GIRKEMKD-VTTKLGEAAQLSCQ 24183
Query: 1028 FSGSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEA 1084
G P PD+ W + G + ++ + + + H+ + + ++ D GVY + NE GE
Sbjct: 24184 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT-LTVMTEEQEDEGVYTCIATNEVGEV 24242
Query: 1085 RYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
+ + P+ L E+ V T H + + R TW+
Sbjct: 24243 ETSSKLLLQATPQFHPGYPLKEKYYGAVGSTL----------RLHVMYIGRPVPAMTWF- 24291
Query: 1145 AAERVFSNKYTVTGLLPGRKYYFRVVARN 1173
+++ N +T + ++Y +V +N
Sbjct: 24292 HGQKLLQNSENIT--IENTEHYTHLVMKN 24318
Score = 252 bits (643), Expect = 2e-66
Identities = 205/799 (25%), Positives = 359/799 (44%), Gaps = 50/799 (6%)
Query: 438 LECELTSKD-VTLRWKK---DG--QLLMHGTKYSMNHEG---KRAELIIEDAQLSDGG-- 486
LE SKD VTL+W+K DG ++L + +Y + + K + I+D Q + GG
Sbjct: 24065 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 24124
Query: 487 -----EYTVVAMQDGDPTEYYSTAIVTVEERLAT-----VKSGMSDVHAATGSPAEL-CV 535
E+ V A + + TA+ +++ +L + ++ M DV G A+L C
Sbjct: 24125 EATEYEFRVFAENETGLSRPRRTAM-SIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24183
Query: 536 VLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKG----TE 591
++ + W + GKE+ ++ G H L + E EG YT A E
Sbjct: 24184 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24243
Query: 592 SEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE 651
+ + + + P P + VG T + V + G+P+P +TW+ +
Sbjct: 24244 TSSKLLLQATPQFHPGYPLKEKYYGA---VGSTLRLHVMYIGRPVPAMTWFHGQKLLQNS 24300
Query: 652 ERVSMERGEDQALLTISNCVRED-SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEF 710
E +++E E L + N R+ +G ++L N G+ A L + + D+P P G +
Sbjct: 24301 ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVI 24360
Query: 711 LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGK 770
L + + WK P D+GG +T ++VE+ + + ++ VT + E
Sbjct: 24361 EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 24420
Query: 771 AYQFRILAVNSEGVSDPLETEEV-FAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDG 829
Y FR+ A N+ G+SDPLE V +P E PG +P +T VTK++ + W P DG
Sbjct: 24421 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDG 24480
Query: 830 GAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSV 889
GA + Y +E+R+K N W+ V + I+ T +V L+E EYEFRV N G + S
Sbjct: 24481 GAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSE 24540
Query: 890 PSSSVVAKD--PVKPPGLVQDL-HVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKE 946
S + K P++ P ++L +++ S+ +L + P + + + E +
Sbjct: 24541 ISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK-EIIAD 24599
Query: 947 WSKCTKIPISGTCY--TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKF 1004
K G + + + + +++RA N+ G G ++ K
Sbjct: 24600 GLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGG------SVSGTASLEVEVPAKI 24653
Query: 1005 DLSARLKSHMVVRA--GTALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQF 1060
L L+ V A G + I FSG P P + WQK D + G + +++ +
Sbjct: 24654 HLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSL 24713
Query: 1061 LI-NSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHS 1119
+ N +R D+G Y + +N FG + + + VAD P PP +++ + ++V LTW
Sbjct: 24714 VFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24773
Query: 1120 PDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
+YI+ ++ A+TA + + +YTV L Y FRV+A N+ G S+
Sbjct: 24774 ASDGGSKITNYIV-EKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSK 24832
Query: 1180 PLDSRDTWLINKDQIQDLS 1198
P + + + +D+ + ++
Sbjct: 24833 PSEPSEPTITKEDKTRAMN 24851
Score = 243 bits (621), Expect = 7e-64
Identities = 306/1277 (23%), Positives = 500/1277 (39%), Gaps = 142/1277 (11%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARV-QGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
EF + + T EG AV V + NAK + W + +G I +S K + + L
Sbjct: 5914 EFTKPLEDQTVEEGATAVLECEVSRENAK--VKWFK-NGTEILKSKKYEIVADGRVRKLV 5970
Query: 127 LEPLTSDDSDNYKCIASN-----------DHADAIYTVSLLVTEGQEKMDFK-------- 167
+ T +D Y C A + H + + ++ L +E F+
Sbjct: 5971 IHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENA 6030
Query: 168 --KMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEM 225
K K A KK ++ + +++K D + E G+L L+E
Sbjct: 6031 KVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEE- 6089
Query: 226 KKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYD 285
EA+ K L + E T+ C E+ P ++IW KG E + G+Y+
Sbjct: 6090 ------EAV-FTKNLANIEVSETDTIKLVC--EVSKPGAEVIWYKGDEEI---IETGRYE 6137
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
+ G K +LVI N ++ DAG Y+ + R ++ V + +F+ + + +++ E + A
Sbjct: 6138 ILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKA 6197
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
F +SK+ WK + K L+ DKY++ DG L +KDA L D G + G
Sbjct: 6198 EFVCSISKESFPVQWKRDDKTLESGDKYDVIA--DGKKRVLVVKDATLQDMGTYVVMVGA 6255
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
A LT+ ++ V LK+ RVKE+ CE+ ++ +W ++ + + +KY
Sbjct: 6256 ARAAAHLTVIE-KLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYI 6314
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ + L I DA L D Y V ++ + S A + VEE + + D+
Sbjct: 6315 ILQKDLVYTLRIRDAHLDDQANYNV-SLTNHRGENVKSAANLIVEEEDLRIVEPLKDIET 6373
Query: 526 ATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
+N V W K+G+E+ + H L G EG+Y
Sbjct: 6374 MEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIV 6433
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
A +S A + I + PT +E L +T ++ + V WY++G
Sbjct: 6434 TAGQDKSVAELLIIEAPT---EFVEHLEDQTVTEFDDAVFSCQL---SREKANVKWYRNG 6487
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
E+ E ++ E+ L I +C +D +++ A + ++ +PPQ
Sbjct: 6488 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQ 6547
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAV--GKKSWIKIGEVDGKVTNFST 763
+ LE G+ V + KD + Q++ V G K + +GK+
Sbjct: 6548 ---DILEAPGADVVFLAELNKD---KVEVQWLRNNMVVVQGDKHQMMS---EGKIHRLQI 6598
Query: 764 NKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWN 823
++ ++R +A + E + E+ A I+ A Q V DV K +
Sbjct: 6599 CDIKPRDQGEYRFIAKDKEARAKL----ELAAAPKIKT---ADQDLVVDVGKPLTMVV-- 6649
Query: 824 APTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAG 883
P Y K W N +P+ TK T+D E T FR++ K
Sbjct: 6650 --------PYDAY-----PKAEAEWFKEN-EPLS-TK-TIDTTAEQTS--FRILEAKKGD 6691
Query: 884 PGQPSV-------PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSG 934
G+ + + + + PG V++L V+++ + +SLAW EP G G
Sbjct: 6692 KGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIG 6751
Query: 935 YILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQ-KYFFRIRAVNEAGVGEPVELDKGV 993
Y++E R K W T S +TV GL + +Y FR+ A N G GEPVE D V
Sbjct: 6752 YVVERRDIKRKTWVLATDRAESCE-FTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPV 6810
Query: 994 RAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD----------VIWQKDGV 1043
A P L+ + V R G +L PP+ VI +D
Sbjct: 6811 EARSKYDVPGPPLNVTITD--VNRFGVSLTWE-------PPEYDGGAEITNYVIELRDKT 6861
Query: 1044 PTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDI---HVRVAD---FPR 1097
+ +T + +R+ QN G + V+VAD P
Sbjct: 6862 SIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPS 6921
Query: 1098 PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSN-KY 1154
PP NL ++ ++V L W P +++ G YII + + W ++ Y
Sbjct: 6922 PPVNLTSSDQTQSSVQLKWE--PPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTY 6979
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPR 1214
VTGL G KY +RV A N+ G S+P + L D + + L ++ P
Sbjct: 6980 KVTGLEKGNKYLYRVSAENKAGVSDPSEILGP-LTADDAFVEPTMDLSAFKDGLEVIVPN 7038
Query: 1215 FVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPT 1274
+T L P T G PRPT T GD + + + S LVI
Sbjct: 7039 PITILVPST--------------GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISP 7084
Query: 1275 CTLKDSGDYSVLVENEL 1291
D G Y++ +EN +
Sbjct: 7085 SERSDKGIYTLKLENRV 7101
Score = 208 bits (529), Expect = 3e-53
Identities = 167/633 (26%), Positives = 273/633 (43%), Gaps = 66/633 (10%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
D P PP R+E +++ V + W P D+GG P+T + VER W++ ++ K
Sbjct: 7509 DPPGPPT-RLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD 7567
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVTKEA 817
T + + K Y+FR+LA N G P + TE + +PI+PP +P V DV K +
Sbjct: 7568 TTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTS 7627
Query: 818 VTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVI 877
V + W P DGGA + Y++E K G++ WV V + + T+ + GL+E EY FRV
Sbjct: 7628 VRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVR 7686
Query: 878 AVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGY 935
AVNKAG +PS PS V+ ++ + PP + L V + + ++ L W P + G P + Y
Sbjct: 7687 AVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNY 7746
Query: 936 ILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRA 995
I+E R K W + + T TV L E Y FR+ A N G + E++ V A
Sbjct: 7747 IVEKRDVRRKGW-QTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLA 7805
Query: 996 M-------PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD---------VIWQ 1039
PP A D++ R H PP + VI +
Sbjct: 7806 KDTFTTPGPPYALAVVDVTKR---------------HVDLKWEPPKNDGGRPIQRYVIEK 7850
Query: 1040 KDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADF---- 1095
K+ + T+ + + F + +++ +NE G +
Sbjct: 7851 KERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPT 7910
Query: 1096 --PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFS 1151
P PP +L + + + + W P + G Y + T W R
Sbjct: 7911 SPPSPPLDLHVTDAGRKHIAIAWK--PPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 7968
Query: 1152 N-KYTVT-GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
+ K+ V G++P ++Y RV A N IG SEP + + ++ KD + L+ ++
Sbjct: 7969 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISEN-VVAKDPDCKPTIDLETHDI--- 8024
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
V+ G+ ++ F P PTV+ +K + A+ + +
Sbjct: 8025 -------------IVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8071
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L +P D+G Y++ +EN+LG +S + V
Sbjct: 8072 LEVPKSVRADAGIYTITLENKLGSATASINVKV 8104
Score = 208 bits (529), Expect = 3e-53
Identities = 143/432 (33%), Positives = 213/432 (49%), Gaps = 26/432 (6%)
Query: 762 STNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTIT 821
+ N+ + GK + + NS G V ++ PG +V +VTK +VT+T
Sbjct: 15548 NVNRFDSGK---YILTVENSSGSKSAFVNVRV-----LDTPGPPQDLKVKEVTKTSVTLT 15599
Query: 822 WNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNK 881
W+ P DGG+ + YIVE+R+ + V + T VD L E Y FRV+A N+
Sbjct: 15600 WDPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENE 15658
Query: 882 AGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEM 939
G G P+ + SV A + PPG + + D + +S+SL+W +P G GYI+EM
Sbjct: 15659 YGIGLPAETAESVKASERPLPPGKIT---LMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15715
Query: 940 RAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP 999
+ + + +W+ C + ++ T+ GLI+ ++Y FR+ A NE G+ +P +L V A
Sbjct: 15716 QTKGSDKWATCATVKVTEA--TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV 15773
Query: 1000 AAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKG--RETITKSKNH 1057
P F L L + V AG L + F G P P V W KD VP K R ++N+
Sbjct: 15774 IPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN 15830
Query: 1058 SQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTW 1116
S I R D G Y + L N GEA ++V V D P PPT +++ E +++TL+W
Sbjct: 15831 SLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSW 15890
Query: 1117 NHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNE 1174
P + G + +YI+ KRD ST TW + V L G +Y FR+ A N
Sbjct: 15891 G--PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENR 15948
Query: 1175 IGDSEPLDSRDT 1186
G S L+S T
Sbjct: 15949 YGKSTYLNSEPT 15960
Score = 204 bits (518), Expect = 6e-52
Identities = 122/391 (31%), Positives = 190/391 (48%), Gaps = 6/391 (1%)
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N I P + + D+TK++V +TW P DGG+P+ GY+VE+R+ W V D +
Sbjct: 7111 NVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDFV 7169
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ TV L++ EY F+V A NK GPG+P+ V P P +++ D +
Sbjct: 7170 TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTA 7229
Query: 917 SSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+SI L W P G GYI+E + +W C + P++ T V GL E + Y +R
Sbjct: 7230 NSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGE-PVAETKMEVTGLEEGKWYAYR 7288
Query: 975 IRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPP 1034
++A+N G +P + ++A+ AP+ L +L + + V+AGT + + A +G P P
Sbjct: 7289 VKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP 7348
Query: 1035 DVIWQKDGVPTKG--RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV 1092
+ W K + K R TI S I +KRSD+G Y I N G A + V V
Sbjct: 7349 KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7408
Query: 1093 ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSN 1152
D P PP + + + LTWN D +Y++ +R + W+ + V
Sbjct: 7409 LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDT 7468
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ T L+P ++Y FRV A N G EP+ +
Sbjct: 7469 NFKATKLIPNKEYIFRVAAENMYGVGEPVQA 7499
Score = 201 bits (512), Expect = 3e-51
Identities = 144/532 (27%), Positives = 249/532 (46%), Gaps = 31/532 (5%)
Query: 168 KMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKK 227
K K P K + V+ K +L + D + +T G L E K
Sbjct: 2780 KWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGE------YTAVVGQL----ECKA 2829
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K+ VE + I K +++ E T F+C E+ NV +W+K + + K+ +
Sbjct: 2830 KLFVETLHITKTMKNIEVPETKTASFEC--EVSHFNVPSMWLKNGVEIEMSE---KFKIV 2884
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G + L+I N + D+ Y+ G+ ++SA LTV P+ +K + E+ T F
Sbjct: 2885 VQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVT--PIMITSMLKDINAEEKDTITF 2942
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E+ ++ + ++ W NG E+K DK ++ + LTH+L I++ D+ +++ AG
Sbjct: 2943 EVTVNYEGISYKWLKNGVEIKSTDKCQMRTKK--LTHSLNIRNVHFGDAADYTFVAGKAT 3000
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A L ++ I+F ++K+++V E+ RA ECE++ D+T++W KD Q L + +
Sbjct: 3001 STATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQ 3060
Query: 468 HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT 527
E L+I ++SD G+YTVVA + STA + VE R ++S +V
Sbjct: 3061 KEKYVHRLLIPSTRMSDAGKYTVVAGGN------VSTAKLFVEGRDVRIRSIKKEVQVIE 3114
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEIT--DLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A + +N++ V+ W KDG EI + V + +H++ G+YTF
Sbjct: 3115 KQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTF 3174
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
A S ++++ P P VL+ L +TV+ G A G+P PK++WYK+
Sbjct: 3175 VAGRNRSSVTLYVNAPE--PPQVLQEL--QPVTVQSGKPARFCAVISGRPQPKISWYKEE 3230
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
++ + + L + ED+ + + KND+G AT + LSV
Sbjct: 3231 QLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 201 bits (512), Expect = 3e-51
Identities = 137/438 (31%), Positives = 208/438 (47%), Gaps = 44/438 (10%)
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
PG + +D+TK + +TW P DGG P+L Y++ERR+ G ++PV +
Sbjct: 8108 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENK-LSW 8166
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
TV L+ + EY FRV AVNK G G+ + V+A+DP +PP D+ V + + ++++
Sbjct: 8167 TVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTI 8226
Query: 922 AWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVN 979
W+ P G GYI+E A+ + W +C + + YT GL E ++Y FR+RA N
Sbjct: 8227 TWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAEN 8286
Query: 980 EAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQ 1039
AG+ EP +A+ P APK L++ + V+ G + + A+ SGSP P + W
Sbjct: 8287 AAGISEPSRATPPTKAVDPIDAPK----VILRTSLEVKRGDEIALDASISGSPYPTITWI 8342
Query: 1040 KDG------------------------------VPTKGRETITKS-KNHSQFLINSTKRS 1068
KD +P R +I S K SQ + + R
Sbjct: 8343 KDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP 8402
Query: 1069 DSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNT-VTLTWNHSPDVQEDGE 1127
D G+Y I ++N+ G A+ V V D P PP N +FE++ T V W D
Sbjct: 8403 DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEI 8461
Query: 1128 AHYIIMKRDAS--TATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+Y + K+D + + W + KY+VT L+ G++Y FRV A N G P S+
Sbjct: 8462 INYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKP 8521
Query: 1186 TWLINKDQIQDLSAKLKP 1203
L+ KD A KP
Sbjct: 8522 --LVAKDPFGPPDAPDKP 8537
Score = 201 bits (510), Expect = 5e-51
Identities = 167/595 (28%), Positives = 274/595 (46%), Gaps = 38/595 (6%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+ P +D L++ I V+ G +A I +PF+G+P P++TW ++ E T+ +V +E+G
Sbjct: 17648 EAPELD---LDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD--KVQIEKG 17702
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
+ L+I NC R D+G +LKL+N GS +A + + VLD P PPQ + E+
Sbjct: 17703 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQN-LAVKEVRKDSAF 17761
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAV 779
+ W+ P +GG V +++++R +K++ + K T+F + EG Y FR++A
Sbjct: 17762 LVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLTEGAIYYFRVMAE 17820
Query: 780 NSEGVSDPLET-EEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
N GV P+ET + V A P PPG + +TDV++ + ++ W P DGG+ VLGY+V
Sbjct: 17821 NEFGVGVPVETVDAVKAAEPPSPPGKVT---LTDVSQTSASLMWEKPEHDGGSRVLGYVV 17877
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
E + KG+ W V + + V GL EY+FRV A N+ G P V V+AKD
Sbjct: 17878 EMQPKGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 17935
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGT 958
P L + + S + L P G P E K+ T++ + T
Sbjct: 17936 LTIQPSLKLPFN-TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQ---TTRVNVEET 17991
Query: 959 C-YTVGGLIERQKYFF---RIRAVNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSH 1013
TV + E K F + A N AG E + + + PP +FD + +
Sbjct: 17992 ATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFD---EVSAD 18048
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
VV + A G + I +K T ++ + + I K +
Sbjct: 18049 FVVISWEP---PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQF 18105
Query: 1074 RILLQNEFGE-ARYDIHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE- 1127
RI +N +G+ A D + + P PP + + + + W H P V + G
Sbjct: 18106 RIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQW-HEP-VNDGGTK 18163
Query: 1128 -AHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
Y + +++ ++ W + + K+ TGL G +Y F+V A N +G +P
Sbjct: 18164 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKP 18218
Score = 200 bits (509), Expect = 7e-51
Identities = 157/596 (26%), Positives = 262/596 (43%), Gaps = 26/596 (4%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+PP + +L+A A +KVG T + +G P PKVTW K+ + + R+ +
Sbjct: 10842 EPPEL---ILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPV 10898
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
+ L I N ED G+ L ++N GS T ++ + VLD+P PP+ +E E+ +
Sbjct: 10899 GSK--LEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRD-LEVSEIRKDSCY 10955
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAV 779
+ WK P D+GG +T ++VERR V W + K ++F+ + + EG Y FR+ A
Sbjct: 10956 LTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH-LNEGNQYLFRVAAE 11014
Query: 780 NSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
N G +ET + + A +P+ PPG DV K V++ WN P +DGG+P+ GY+V
Sbjct: 11015 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11074
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
E +++G+ W+ + +C V GL + Y FRV A N G G P + + ++
Sbjct: 11075 EYQEEGTQDWIKFK--TVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDT-TIPIECQE 11131
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDP-PSGYILEMRAEDTKEWSKCTKIPI 955
+ PP + D+ + + R PA G P P+ +E + +
Sbjct: 11132 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11191
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
+ T+ + R ++I N AG + V + V +P P ++ HM
Sbjct: 11192 FSSVLTIKNCLRRDTGEYQITVSNAAG-SKTVAVHLTVLDVPGPPTGPINILDVTPEHMT 11250
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
+ GSP + I +K ++ + ++ I ++ V+R+
Sbjct: 11251 ISWQPP----KDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRV 11306
Query: 1076 LLQNEFG-----EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHY 1130
+N+ G ++ + P PP + + N T++W P
Sbjct: 11307 RAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWT-LPKSDGGSPITG 11365
Query: 1131 IIMKRDASTATWYTAAERVFSN-KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
M+R T W + ++ K+ VTGL G Y FRV A N G S+P S D
Sbjct: 11366 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11421
Score = 196 bits (497), Expect = 2e-49
Identities = 174/653 (26%), Positives = 280/653 (42%), Gaps = 42/653 (6%)
Query: 567 VHKLIFPSMGPEHEGKYTFRAKGTESEASV---------FIADPPTIDPSVLEALAAHAI 617
V +L + G E KY +R E++A V AD ++P++ + +
Sbjct: 6974 VPELTYKVTGLEKGNKYLYRVSA-ENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGL 7032
Query: 618 TVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGL 677
V V + I VP G P P TW + +RV M+ A L IS R D G+
Sbjct: 7033 EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGI 7092
Query: 678 ILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFI 737
LKL+N + + + ++V+ RP P+ ++F +++ VH+ W+ P D+GG P+T ++
Sbjct: 7093 YTLKLENRVKTISGEIDVNVIARPSAPK-ELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 7151
Query: 738 VERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAG 796
VE+R V +K+W K+ + + F+ + +GK Y F++ A N G +P +E V
Sbjct: 7152 VEKREVSRKTWTKVMDFVTDL-EFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMS 7210
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
P P + D T ++ +TW+ P DGG+ + GYIVER +GS+ WV +P+
Sbjct: 7211 TPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG-EPV 7269
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
TK V GL E Y +RV A+N+ G +PS P+ + A D + P + D+ +
Sbjct: 7270 AETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLT 7329
Query: 917 SSISLAWREPAE-GDPPSGYILEMRAEDTKEWSK---CTKIPISGTCYTVGGLIERQKYF 972
PA P I +A+ + K +P T T+
Sbjct: 7330 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST-VTIVDSKRSDTGT 7388
Query: 973 FRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSP 1032
+ I AVN G V + PPAA FD++ ++ GS
Sbjct: 7389 YIIEAVNVCGRATAVVEVNVLDKPGPPAA--FDITDVTNESCLLTWNPP----RDDGGSK 7442
Query: 1033 PPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---------- 1082
+ + ++ ++ ++ + + F + ++R+ +N +G
Sbjct: 7443 ITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPI 7502
Query: 1083 EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATW 1142
A+Y D P PPT L + + VTLTW D Y + + D T W
Sbjct: 7503 TAKYQF-----DPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKW 7557
Query: 1143 YTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQI 1194
+ V Y V GL +KY FRV+A N G +P S + LI KD I
Sbjct: 7558 VRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI-KDPI 7609
Score = 196 bits (497), Expect = 2e-49
Identities = 143/520 (27%), Positives = 238/520 (45%), Gaps = 28/520 (5%)
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
L+ P+PP E L+++ S V + W PKD+GG VT + +ER+ W++ +
Sbjct: 23954 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 24013
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKE 816
T ++ + YQFRI+A N G+S+ E V +P + P + ++ ++K+
Sbjct: 24014 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 24073
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
+VT+ W P DGG +LGY VE R+ G + W NK+ I+ + T+ GLLE TEYEFRV
Sbjct: 24074 SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRV 24133
Query: 877 IAVNKAGPGQPSVPSSSVVAK-DPVKPPGLVQDLH-----VSDSSNSSISLAWREPAEGD 930
A N+ G +P + S+ K + PG+ +++ + +++ S + R
Sbjct: 24134 FAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGR------ 24187
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKY--FFRIRAVNEAGVGEPVE 988
P I R S+ K+ G +T+ + E Q+ + A NE G E
Sbjct: 24188 -PLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG-----E 24241
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGR 1048
++ + + A P+F LK G+ L +H + G P P + W +
Sbjct: 24242 VETSSKLLLQ-ATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNS 24300
Query: 1049 ETIT-KSKNHSQFLI--NSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLF 1105
E IT ++ H L+ N +++ +G Y++ L N FG + V + D P PT +
Sbjct: 24301 ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVI 24360
Query: 1106 EEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDAST-ATWYTAAERVFSNKYTVTGLLPGR 1163
E + N+ ++W D +Y++ K +A A W + + + L
Sbjct: 24361 EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 24420
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203
YYFRV A+N G S+PL+ +I K + A KP
Sbjct: 24421 GYYFRVSAQNTFGISDPLEVSSVVII-KSPFEKPGAPGKP 24459
Score = 195 bits (496), Expect = 2e-49
Identities = 163/617 (26%), Positives = 271/617 (43%), Gaps = 43/617 (6%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ E ++ + + W P +GG + +IVERR + WIK +
Sbjct: 15283 PDPPKNP-EVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR 15341
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVT 819
+ + + EG Y+FRI+A N+ G+S P T + A + + PG P+V D ++ +++
Sbjct: 15342 YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSIS 15401
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLEDTEYEFRVIA 878
I WN P DGG+ + GY+VE + W V ++ T T+ GL E+ EY+ R+ A
Sbjct: 15402 IAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYA 15461
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPG--LVQDLHVSDSSNSSISLAWREPAEGDPPSGYI 936
+N G G+P++ + A+D + PP L DL + + +L P +G P
Sbjct: 15462 MNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPE-- 15519
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
++ + + K + S + G + R I V + + ++ VR +
Sbjct: 15520 VKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVN--VRVL 15577
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKS 1054
P P+ LK V + L GS + I +K K T+ +
Sbjct: 15578 DTPGPPQ-----DLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATN 15632
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNT 1111
+ + + ++ + S +R+L +NE+G A V+ ++ P PP + L + N+
Sbjct: 15633 CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS 15692
Query: 1112 VTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFR 1168
V+L+W + DG + YI+ + + W T A V + T+TGL+ G +Y FR
Sbjct: 15693 VSLSWEKP---EHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFR 15748
Query: 1169 VVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQ 1228
V A+NE G S+P + LS P KD P F TVL G+
Sbjct: 15749 VSAQNEKGISDP--------------RQLSV---PVIAKDLVIPPAFKLLFNTFTVLAGE 15791
Query: 1229 DCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVE 1288
D + F+G P P VT +K +V + ++ ST L I +D G Y V +
Sbjct: 15792 DLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLT 15851
Query: 1289 NELGKDRSSCTLTVYDK 1305
N G+ + + V DK
Sbjct: 15852 NSAGEAIETLNVIVLDK 15868
Score = 193 bits (491), Expect = 8e-49
Identities = 124/393 (31%), Positives = 189/393 (48%), Gaps = 9/393 (2%)
Query: 799 IEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG 858
++ PG +V+++ K++ +TW P DGG+ + Y+VERR S W P++ +
Sbjct: 10935 LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKK 10994
Query: 859 TKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSS 918
+ L E +Y FRV A N+ G G + A DP+ PPG +DLH D +
Sbjct: 10995 SHFAKH-LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTE 11053
Query: 919 ISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIR 976
+SL W +P G P +GY++E + E T++W K + + V GL + + Y FR++
Sbjct: 11054 VSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTV--TNLECVVTGLQQGKTYRFRVK 11111
Query: 977 AVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
A N G+G P + + P +L +L +VV+AGT + A G P P
Sbjct: 11112 AENIVGLGLP-DTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTA 11170
Query: 1037 IWQKDGVPTKGRETIT-KSKNHSQFL-INSTKRSDSGVYRILLQNEFGEARYDIHVRVAD 1094
W DG K E T ++ N S L I + R D+G Y+I + N G +H+ V D
Sbjct: 11171 KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD 11230
Query: 1095 FPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNK 1153
P PPT + + + P +T++W D +YI+ K+D TW + K
Sbjct: 11231 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 11290
Query: 1154 YTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDT 1186
+ L G +Y FRV A N+IG PLDS T
Sbjct: 11291 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPT 11323
Score = 193 bits (491), Expect = 8e-49
Identities = 194/806 (24%), Positives = 335/806 (41%), Gaps = 105/806 (13%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
W KDG + G+++ Q + L S+ + G YT A+ + S TI
Sbjct: 12957 WKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSA------TIK 13010
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKD----GMEVT-----EEERVSM 656
VL+ K G A +K+ ++W G E+T + E
Sbjct: 13011 LKVLD---------KPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRP 13061
Query: 657 ERGEDQALLTISNC-----VREDSGLILLKLKNDHGSATATL-HLSVLDRPKPPQGRVE- 709
+ A + I++C + + +N +G ++ P P GR +
Sbjct: 13062 NWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 13121
Query: 710 --FLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVE 767
++ + + WK P D+GG P+T +++E+R +W K+ ++
Sbjct: 13122 PVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQ 13181
Query: 768 EGKAYQFRILAVNSEGVSDPLETEEV-FAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
EG Y+FR+ A+N G P + + +A +P PPG + P+V D T+ +V+++W P
Sbjct: 13182 EGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13241
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVN-KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPG 885
DGG+P++GY+VE ++ S+ WV N +Q T+ V GL+EDT+Y+FRV AVNK G
Sbjct: 13242 YDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYS 13301
Query: 886 QPSVPSSSVVAKDPVKPPG--LVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAED 943
PS KD + PP L DL + + +++ P +G PP
Sbjct: 13302 DPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKIT------- 13354
Query: 944 TKEWSKCTKIPISGTCYTVGGLIERQKY--FFRIRAVNEAGVGEPV----------ELDK 991
WSK P +G I+ + F R VN+ G+ + E
Sbjct: 13355 ---WSK----PNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTI 13407
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI 1051
V+ + P P ++ +K A GSP + + QK K T+
Sbjct: 13408 VVKVLDTPGPP---VNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 13464
Query: 1052 TKSKNHSQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRLFE 1106
T + + F + + + S +R+ +NE+G E R V+ + P P +L++
Sbjct: 13465 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTPGPVVDLKVRS 13522
Query: 1107 EVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTAT--WYTAAERVFSNKYTVTGLLPGRK 1164
++ ++ W DG + I D T W + + S +Y+ L G++
Sbjct: 13523 VSKSSCSIGWKKP---HSDGGSRIIGYVVDFLTEENKWQRVMKSL-SLQYSAKDLTEGKE 13578
Query: 1165 YYFRVVARNEIGDSEPLDSRDTWLINKDQI--QDLSAKLKP---YEKKDWRHAPRFVTPL 1219
Y FRV A NE G+ P + ++ +D + DL K P Y K+ + R P+
Sbjct: 13579 YTFRVSAENENGEGTP---SEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF-RLKIPI 13634
Query: 1220 KPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKD 1279
K G P P+V+ KG+ + +++ S++ TL++ C D
Sbjct: 13635 K-----------------GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSD 13677
Query: 1280 SGDYSVLVENELGKDRSSCTLTVYDK 1305
+G Y++ ++N G + ++ V K
Sbjct: 13678 AGKYTITLKNVAGTKEGTISIKVVGK 13703
Score = 193 bits (490), Expect = 1e-48
Identities = 138/458 (30%), Positives = 214/458 (46%), Gaps = 43/458 (9%)
Query: 749 IKIGEVDGKV------------TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
+K G+VDG++ T+ + V + ++ + NS G T V
Sbjct: 16602 VKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRV--- 16658
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
++ P +VT++TK++V+ITW P DGG+ + YIVE+R+ + V +
Sbjct: 16659 --LDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTN-C 16715
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+D L E Y FRV A N+ G G P+ + + + +PPG + V D +
Sbjct: 16716 HKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKIT---VDDVTR 16772
Query: 917 SSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+S+SL+W +P G YI+EM+A+ +++WS+C ++ T L + ++Y FR
Sbjct: 16773 NSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVIT--NLTQGEEYLFR 16830
Query: 975 IRAVNEAGVGEPVELDKGVRA----MPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSG 1030
+ AVNE G +P L + A + P P F S V+ G L I SG
Sbjct: 16831 VVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAF-------SSYSVQVGQDLKIEVPISG 16883
Query: 1031 SPPPDVIWQKDGVPTK--GRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDI 1088
P P + W KDG+P K R +T S + + I T + D G Y I + N G+ I
Sbjct: 16884 RPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASI 16943
Query: 1089 HVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDG--EAHYIIMKRDASTATWYTA 1145
+ D P PP F++V ++TL+WN P + G +YI+ KRD +T W
Sbjct: 16944 EIVTLDKPDPPKGPVKFDDVSAESITLSWN--PPLYTGGCQITNYIVQKRDTTTTVWDVV 17001
Query: 1146 AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ V VT L G +Y FR+ A N G S L+S
Sbjct: 17002 SATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALES 17039
Score = 191 bits (486), Expect = 3e-48
Identities = 152/474 (32%), Positives = 218/474 (45%), Gaps = 34/474 (7%)
Query: 730 GRPVTQF-IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVS--- 785
G P+ F IV R K +W K+G +D V + V+ F ++ ++ S
Sbjct: 12249 GCPIRLFAIVRGRPAPKVTWRKVG-IDNVVRKGQVDLVD---TMAFLVIPNSTRDDSGKY 12304
Query: 786 -----DPLETEEVFAG-NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE 839
+P + VF ++ PG S +V+DVTK + ++W P DGG+ V YIVE
Sbjct: 12305 SLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVE 12364
Query: 840 RRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDP 899
+R+ W V + ++ T V L+ EY FRV AVN+ GPG P+ V+A DP
Sbjct: 12365 KREADRKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12423
Query: 900 VKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAED--TKEWSKCTKIPI 955
+ P + L V++ + +S +LAW P G GYI R E+ W++ + +
Sbjct: 12424 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYS--VV 12481
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
V GL E +KY FR+ A N GV P E + A PK + +
Sbjct: 12482 KDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI----LMPEQIT 12537
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
++AG L I A G P P W+K D V T + K+ + S +I R DSG Y
Sbjct: 12538 IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYY 12597
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEA---H 1129
+ +N G I V V D P PP ++ + +L+W H P EDG + +
Sbjct: 12598 SLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSW-HIP--LEDGGSNITN 12654
Query: 1130 YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
YI+ K D S W TA V V L+PG++Y FRV A N G SEPL S
Sbjct: 12655 YIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTS 12708
Score = 191 bits (485), Expect = 4e-48
Identities = 165/599 (27%), Positives = 252/599 (42%), Gaps = 54/599 (9%)
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L+A I V G I GKP P VTW + E T + ++E + + I
Sbjct: 10154 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMN--ERTLPQEATIETTAISSSMVIK 10211
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
NC R G+ L KN+ G T+ + VLD P P L+ + W +P+D+
Sbjct: 10212 NCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDD 10271
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG P+T +++E+R +++W + + N + + +GKAY FRI A NS G+ +
Sbjct: 10272 GGSPITNYVIEKRESDRRAWTPVTYTVTR-QNATVQGLIQGKAYFFRIAAENSIGMGPFV 10330
Query: 789 ETEEVFA-GNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNL 847
ET E PI P +V +VTK VT+TWN P DGG+ ++ Y++E R G+
Sbjct: 10331 ETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 10390
Query: 848 WVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
+ V D + K TV GL E YE+RV AVN G G+PS + + KD + PP L
Sbjct: 10391 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 10450
Query: 908 DLH--VSDSSNSSISLAWREPAEGDPPSGYILEMR--AEDTKEWSKCTKIPI-------- 955
D ++ + +L R + P + + ED + K T +
Sbjct: 10451 DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAK 10510
Query: 956 ---SGT-CYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLK 1011
SG C V +K F ++ V+ G PP FD K
Sbjct: 10511 RSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--------------PPVGPVSFD--EVTK 10554
Query: 1012 SHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSG 1071
+MV+ L GS + I +K V +T + + ++
Sbjct: 10555 DYMVISWKPPL----DDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY 10610
Query: 1072 VYRILLQNEFG--------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQ 1123
++RI +N +G + RV D P P + E ++ +TWN D
Sbjct: 10611 IFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPI---VTEVTKDSALVTWNKPHDGG 10667
Query: 1124 EDGEAHYIIMKRDASTATWYTAAERVFS--NKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
+ +YI+ KR+ + W + K+ V LL G +Y FRV A NEIG +P
Sbjct: 10668 KP-ITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDP 10725
Score = 191 bits (484), Expect = 5e-48
Identities = 126/394 (31%), Positives = 187/394 (47%), Gaps = 11/394 (2%)
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N ++ PG +VT+VTKE TI+W P +GG+ + +IVE RK W V D
Sbjct: 11625 NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVT 11684
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ + LL + EY FRV A NK G G + ++A +P+ PG ++LH++D
Sbjct: 11685 K--RLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGK 11742
Query: 917 SSISLAWREP--AEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+ + L WR P G P Y +E R + + +W + K I T Y V +E Q Y FR
Sbjct: 11743 TFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFR 11802
Query: 975 IRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPP 1034
++ NE G + V+ ++ V P DL +L + V+AG + + A G P P
Sbjct: 11803 VQTKNEGGESDWVKTEE-VVVKEDLQKPVLDL--KLSGVLTVKAGDTIRLEAGVRGKPFP 11859
Query: 1035 DVIWQKDGVPT----KGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHV 1090
+V W KD T R I + S+F + KRSD G Y + N G V
Sbjct: 11860 EVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATV 11919
Query: 1091 RVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF 1150
V D P P NL++ + + T+ W+ D +YI+ K + W T + V
Sbjct: 11920 NVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVL 11979
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ TVT L+ G +Y FRV A N+IG P +S+
Sbjct: 11980 TPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESK 12013
Score = 189 bits (481), Expect = 1e-47
Identities = 158/580 (27%), Positives = 258/580 (44%), Gaps = 42/580 (7%)
Query: 619 VKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLI 678
V+ G + + + ++G+P P W K ++ R + + + LT+ NC R D+G
Sbjct: 21997 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL--RADIHTTDSFSTLTVENCNRNDAGKY 22054
Query: 679 LLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIV 738
L ++N+ GS + T + VLD P PP G + F +++ + W AP +GG + ++V
Sbjct: 22055 TLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGARIHHYVV 22113
Query: 739 ERRAVGKKSWIKIGEVDGKVTN--FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
E+R ++SW I E K T F N + EG Y FR+ AVN GV +P E E
Sbjct: 22114 EKREASRRSWQVISE---KCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVA 22170
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
E P + V D +K + + W P DGG+ + GY++E R+KGS+ WV
Sbjct: 22171 T--EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH--T 22226
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPP-----GLVQDLHV 911
+ TV+ L+E TEYEFRV A N AG +P SSV+ K+P P G+ L +
Sbjct: 22227 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQL-I 22285
Query: 912 SDSSNSSISLAWREPAEGDPP---SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ + S ++ P G P + + EMR ++T S T T TV +
Sbjct: 22286 TCKAGSPFTI--DVPISGRPAPKVTWKLEEMRLKETDRVSITT--TKDRTTLTVKDSMRG 22341
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAF 1028
+ + N AGV + + V P P ++S+ V+ G
Sbjct: 22342 DSGRYFLTLENTAGV-KTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEP----KDG 22396
Query: 1029 SGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR-YD 1087
G+ + I +K T + + S +Q + + +R+ +N FG ++ +
Sbjct: 22397 GGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE 22456
Query: 1088 IHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTA 1140
+A+ P PT ++ N +++ W + DG + Y + K++ +T
Sbjct: 22457 SAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWE---EPYHDGGSKIIGYWVEKKERNTI 22513
Query: 1141 TWYTAAE-RVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
W + Y VTGL+ G +Y FR A N G S+
Sbjct: 22514 LWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSK 22553
Score = 189 bits (480), Expect = 2e-47
Identities = 192/770 (24%), Positives = 305/770 (39%), Gaps = 73/770 (9%)
Query: 570 LIFPSMGPEHEGKYTFRAKGTESEAS------VFIADPPTIDPSVLEALAAHAITVKVGH 623
L+ P G YT A AS V P + P E+++A +T+
Sbjct: 9809 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSW-- 9866
Query: 624 TAHIKVPFRGKPLPKVTWYK-DGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKL 682
P + K+T Y + E + V + + TI + + +
Sbjct: 9867 -----FPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMA 9921
Query: 683 KNDHGSA--------TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
+N +G TA SV P P ++ + + + W+ P+ +GG PVT
Sbjct: 9922 QNKYGIGEPLDSEPETARNLFSVPGAPDKPT----VSSVTRNSMTVNWEEPEYDGGSPVT 9977
Query: 735 QFIVERRAVGKKSWIKIGEVDGKV----TNFSTNKVEEGKAYQFRILAVNSEGVSDP-LE 789
+ +E + K W ++ K ++ + EG YQFR+ A+N+ GV L
Sbjct: 9978 GYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLP 10037
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
++ A +PI PPG P+VTD TK + + W+ P +DGG+ V GYIVE +++G W
Sbjct: 10038 SDPATARDPIAPPG-PPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWE 10096
Query: 850 PVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDL 909
++GTK V GL E Y+FRV AVN AG G+P + + KD + P L D
Sbjct: 10097 KGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDA 10156
Query: 910 HVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIE 967
V D R A G PP M + + IS + +
Sbjct: 10157 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSM-VIKNCQR 10215
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
+ + + A NEAG + + V +P P F +H + L +
Sbjct: 10216 SHQGVYSLLAKNEAGERKKTII-VDVLDVPGPVGTPF------LAHNLTNESCKLTWFSP 10268
Query: 1028 FS--GSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG--- 1082
GSP + + +K + +T + + + + +RI +N G
Sbjct: 10269 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10328
Query: 1083 --EARYDIHVRVA-DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDA 1137
E + +R P P +L + E NTVTLTWN P + G +Y++ R
Sbjct: 10329 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWN--PPKYDGGSEIINYVLESRLI 10386
Query: 1138 STATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQD 1196
T ++ + + S KYTV GL G Y +RV A N +G +P
Sbjct: 10387 GTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP---------------- 10430
Query: 1197 LSAKLKPYEKKDWRHAPRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITA 1255
S KP KD P + +R G+ +T + G P+P V+ +K + ++
Sbjct: 10431 -SFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10489
Query: 1256 NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+ + +T L DSG Y V+VEN G + C + V D+
Sbjct: 10490 DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 10539
Score = 188 bits (477), Expect = 3e-47
Identities = 110/321 (34%), Positives = 176/321 (54%), Gaps = 12/321 (3%)
Query: 590 TESEASVFIADP---PTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
+E +V DP PTID L H I V G I VPFR P+P V+W+KDG
Sbjct: 8000 SEISENVVAKDPDCKPTID------LETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGK 8053
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
EV +R++M+ A L + VR D+G+ + L+N GSATA++++ V+ P P +
Sbjct: 8054 EVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKD 8113
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
++ +++ S + W+ P+ +GG P+ +++ERR G++++I + + K++ + +
Sbjct: 8114 -IKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLI 8172
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
G+ Y FR+ AVN G + +E + V A +P +PP +V + T EA+TITW P
Sbjct: 8173 PNGE-YFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPP 8231
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPG 885
DGG+ ++GYI+E+ KG W N+ + T GL E EY+FRV A N AG
Sbjct: 8232 LYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGIS 8291
Query: 886 QPSVPSSSVVAKDPVKPPGLV 906
+PS + A DP+ P ++
Sbjct: 8292 EPSRATPPTKAVDPIDAPKVI 8312
Score = 187 bits (475), Expect = 6e-47
Identities = 164/601 (27%), Positives = 274/601 (45%), Gaps = 52/601 (8%)
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
PP I+ L+A +T++ T + VP +G+P P+V W +D E ++ S+E
Sbjct: 15485 PPEIE---LDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGE--SLDKASIESTS 15539
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHM 720
LL + N R DSG +L ++N GS +A +++ VLD P PPQ ++ E++ + V +
Sbjct: 15540 SYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQD-LKVKEVTKTSVTL 15598
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W P +GG + +IVE+R +K++ + K T++ ++++EG +Y FR+LA N
Sbjct: 15599 TWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHK-TSWKVDQLQEGCSYYFRVLAEN 15657
Query: 781 SEGVSDPLET-EEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE 839
G+ P ET E V A PPG + + DVT+ +V+++W P DGG+ +LGYIVE
Sbjct: 15658 EYGIGLPAETAESVKASERPLPPG---KITLMDVTRNSVSLSWEKPEHDGGSRILGYIVE 15714
Query: 840 RRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDP 899
+ KGS+ W ++ T+ T+ GL++ EY FRV A N+ G P S V+AKD
Sbjct: 15715 MQTKGSDKWATC--ATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDL 15772
Query: 900 VKPPGLV-----------QDLHVSDS--SNSSISLAWREPAEGDPPSGYILEMRAEDTKE 946
V PP +DL V + ++ W + + P + AE T+
Sbjct: 15773 VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWH---KDNVPLKQTTRVNAESTEN 15829
Query: 947 WSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE-LDKGVRAMPPPAAPKFD 1005
S T I C G + ++ N A GE +E L+ V P P
Sbjct: 15830 NSLLT---IKDACREDVG-------HYVVKLTNSA--GEAIETLNVIVLDKPGPPTGPVK 15877
Query: 1006 LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINST 1065
+ + + G GS + I +K T + ++ + +
Sbjct: 15878 MDEVTADSITLSWGPP----KYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRL 15933
Query: 1066 KRSDSGVYRILLQNEFGEARY-DIHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSP 1120
K +RI +N +G++ Y + VA + P PP + +++ + WN
Sbjct: 15934 KTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPI 15993
Query: 1121 DVQEDGEAHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
Y + +++ ++ W + + K+ TGL G +Y FRV A N +G +
Sbjct: 15994 SDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGK 16053
Query: 1180 P 1180
P
Sbjct: 16054 P 16054
Score = 187 bits (474), Expect = 8e-47
Identities = 184/687 (26%), Positives = 294/687 (42%), Gaps = 94/687 (13%)
Query: 560 QIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT------------ESEASVFIADPPTIDPS 607
+I K + + F G +Y FR K ES + I PP ++
Sbjct: 11480 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVE-- 11537
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
L+ ITV+VG T I +G+P P +TW K+G + E+RV + + + L I
Sbjct: 11538 -LDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQI 11596
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKD 727
VR D G ++ KN G A + ++VLDRP P Q +C + W+ P D
Sbjct: 11597 KEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCT-ISWENPLD 11655
Query: 728 NGGRPVTQFIVERRAVGKKSW-IKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSD 786
NGG +T FIVE R +K W I +V ++ + E Y FR+ A N GV
Sbjct: 11656 NGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNE---YYFRVCAENKVGVGP 11712
Query: 787 PLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGS 845
+ET+ + A NPI+ PG + D K V + W P DGG+P L Y VERR KGS
Sbjct: 11713 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11772
Query: 846 NLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL 905
+ W V+K I+ T VD +E+ YEFRV N+ G V + VV K+ ++ P
Sbjct: 11773 DDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVVKEDLQKP-- 11829
Query: 906 VQDLHVSD----SSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT 961
V DL +S + +I L E P + + +D + ++ ++ I +
Sbjct: 11830 VLDLKLSGVLTVKAGDTIRL---EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADS 11886
Query: 962 VGGLIERQKYF----FRIRAVNEAG----------VGEP----------VELDKGVRAMP 997
+ + K + + A N AG + +P V D+
Sbjct: 11887 SKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWD 11946
Query: 998 PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNH 1057
P P+ D ++++++ + T + + +S + V T G T+T+
Sbjct: 11947 P---PEDDGGCEIQNYILEKCETKRMVWSTYSAT-----------VLTPG-TTVTRLIEG 11991
Query: 1058 SQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRLFEEVPNTV 1112
+++ ++R+ +N+ G E++ I D P P + + +
Sbjct: 11992 NEY-----------IFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEM 12040
Query: 1113 TLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGRKYYFRV 1169
T+ WN P + G++ Y + K++ + W + + V LLP +Y FRV
Sbjct: 12041 TVVWN--PPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRV 12098
Query: 1170 VARNEIGDSEP-LDSRDTWLINKDQIQ 1195
A NEIG EP L SR ++ KD I+
Sbjct: 12099 KAENEIGIGEPSLPSRP--VVAKDPIE 12123
Score = 185 bits (470), Expect = 2e-46
Identities = 136/460 (29%), Positives = 206/460 (44%), Gaps = 20/460 (4%)
Query: 730 GRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE 789
GRP + R ++I E T S + + A ++ + NS G
Sbjct: 17678 GRPTPEITWSREEGEFTDKVQI-EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 17736
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
T +V ++ PG V +V K++ + W P DGGA V Y++++R+ +
Sbjct: 17737 TVKV-----LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYA 17791
Query: 850 PVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDL 909
V+ T V+ L E Y FRV+A N+ G G P +V A +P PPG V
Sbjct: 17792 NVSSK-CSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVT-- 17848
Query: 910 HVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIE 967
++D S +S SL W +P G GY++EM+ + T++WS + + T GL
Sbjct: 17849 -LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVT--GLSS 17905
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
Q+Y FR++A NE G +P L V A P L S ++AG L I
Sbjct: 17906 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYS---IQAGEDLKIEIP 17962
Query: 1028 FSGSPPPDVIWQKDGVPTKG--RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR 1085
G P P++ W KDG P K R + ++ + I + D G Y + N G A
Sbjct: 17963 VIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTAT 18022
Query: 1086 YDIHVRVADFPRPPTNLRLFEEVP-NTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
++ V V + P PP F+EV + V ++W ++YI+ KRD +T TW+
Sbjct: 18023 ENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHM 18082
Query: 1145 AAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ V +T L G +Y FR+ A N G S PLDS+
Sbjct: 18083 VSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSK 18122
Score = 184 bits (467), Expect = 5e-46
Identities = 129/458 (28%), Positives = 206/458 (44%), Gaps = 17/458 (3%)
Query: 732 PVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE 791
P + + R + +++ I+ + + + + +G + +LA N G E +
Sbjct: 10182 PTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV---YSLLAKNEAG-----ERK 10233
Query: 792 EVFAGNPIEPPGFASQPQVT-DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP 850
+ + ++ PG P + ++T E+ +TW +P DGG+P+ Y++E+R+ W P
Sbjct: 10234 KTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTP 10293
Query: 851 VNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLH 910
V + TV GL++ Y FR+ A N G G S ++V ++P+ P +DL
Sbjct: 10294 VTYT-VTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE 10352
Query: 911 VSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
V + + ++++L W P G Y+LE R T+++ K T + YTV GL E
Sbjct: 10353 VKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEG 10412
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAF 1028
Y +R+ AVN G G+P K + A P L R K + +R G A + +
Sbjct: 10413 DTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDK--LTIRVGEAFALTGRY 10470
Query: 1029 SGSPPPDVIWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
SG P P V W KD V R I + KRSDSG Y ++++N G +
Sbjct: 10471 SGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKG 10530
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNT-VTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTA 1145
V V D P PP F+EV + ++W D +YII K++ W
Sbjct: 10531 FCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV 10590
Query: 1146 AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
V+ LL G+ Y FR+ A N G S+PL S
Sbjct: 10591 TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVS 10628
Score = 183 bits (465), Expect = 8e-46
Identities = 173/660 (26%), Positives = 266/660 (40%), Gaps = 74/660 (11%)
Query: 582 KYTFRAKGT----ESEASVFIADPPTID----PSVLEALAAH-AITVKVGHTAHIKVPFR 632
KY FR K ESE S + P D P V + A + K G I +
Sbjct: 9404 KYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIK 9463
Query: 633 GKPLPKVTW---------YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLK 683
G+P PK +W KDG+ E+ +E E+ +++ I C R +G + K
Sbjct: 9464 GRPTPKSSWEFDGKAKKAMKDGVHDIPED-AQLETAENSSVIIIPECKRSHTGKYSITAK 9522
Query: 684 NDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAV 743
N G TA + V+D P PP+ GSC + WK P D+GG + +++E+R +
Sbjct: 9523 NKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSC-RLSWKMPDDDGGDRIKGYVIEKRTI 9581
Query: 744 GKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLET-EEVFAGNPIEPP 802
K+W K+ G T + + E + Y FR+ A N G+ P+ET + A +PI PP
Sbjct: 9582 DGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIYPP 9640
Query: 803 GFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE-------RRKKGSNLWVPVNKDP 855
+ ++ +TK V ++W P DGG+PV YIVE KK + W NK
Sbjct: 9641 DPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEA--WRQCNKRD 9698
Query: 856 IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPG--LVQDLHVSD 913
++ + TV+ L+E EYEFRV AVN AG +PS + P PP L + + V +
Sbjct: 9699 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 9758
Query: 914 SSNSSI----------SLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVG 963
+N +I +L W + P + E + K+ + TC V
Sbjct: 9759 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDN-------KEPVLYDTHVNKLVVDDTCTLVI 9811
Query: 964 GLIERQKY-FFRIRAVNEAGVGEPVELDKGVRAMP-PPAAPKFDLSARLKSHMVVRAGTA 1021
R + I AVN G E+ V P PP P + +S + +
Sbjct: 9812 PQSRRSDTGLYTITAVNNLGTASK-EMRLNVLGRPGPPVGP-----IKFESVSADQMTLS 9865
Query: 1022 LCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEF 1081
GS + + +K K ++ + I V+RI+ QN++
Sbjct: 9866 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKY 9925
Query: 1082 G-----EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRD 1136
G ++ + + P P + N++T+ W Y + +D
Sbjct: 9926 GIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKD 9985
Query: 1137 ASTATWYTA-----AERVFSNKYTVTGLLPGRKYYFRVVARNEIG------DSEPLDSRD 1185
++ W Y VTGL+ G Y FRV A N G S+P +RD
Sbjct: 9986 TTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARD 10045
Score = 182 bits (463), Expect = 1e-45
Identities = 168/649 (25%), Positives = 276/649 (42%), Gaps = 83/649 (12%)
Query: 582 KYTFRAKGTESEASVFIADPPTIDPSV------------LEALAAHAITVKVGHTAHIKV 629
+Y FR SE + +P T+ SV L+A + ++ T + V
Sbjct: 18701 EYNFRICAINSEG---VGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFV 18757
Query: 630 PFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA 689
+G+P P+V W K +T+ R +E +L I N R DSG L L+N+ GS
Sbjct: 18758 TIKGRPEPEVKWEKAEGILTD--RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSK 18815
Query: 690 TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
TA +++ VLD P P + E+ V + W+ P +GG +T +IVE+R +K++
Sbjct: 18816 TAFVNVRVLDSPSAPVN-LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18874
Query: 750 KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQP 808
I K T F ++EG +Y FR+LA N G+ P ET E V P PPG +
Sbjct: 18875 TITNNCTKTT-FRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVT-- 18931
Query: 809 QVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
+ DVT+ TI W P DGG+ + GY+VE + KGS W + ++ + T+ GL
Sbjct: 18932 -LVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTA 18988
Query: 869 DTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE 928
EY FRV AVN+ G P V+A+D P + H + ++ RE +
Sbjct: 18989 GEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH-------TFNVKAREQLK 19041
Query: 929 GDPPSGYILEMRAEDTKEWSK-------CTKIPISG----TCYTVGGLIERQKYFFRIRA 977
D P + R + T W K T++ +S T ++ + + +
Sbjct: 19042 IDVP----FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV 19097
Query: 978 VNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP--- 1033
N AG + P+ + V P P P +R C S +PP
Sbjct: 19098 SNSAGSITVPITII--VLDRPGPPGP-------------IRIDEVSCDSITISWNPPEYD 19142
Query: 1034 -----PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY-D 1087
+ I +K + ++++ + I +R+ +N +G++ Y +
Sbjct: 19143 GGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE 19202
Query: 1088 IHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWY 1143
VA++ P PP ++ +T+ +TW + Y + ++ S+ W
Sbjct: 19203 SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWS 19262
Query: 1144 TAAERVFSN-KYTVTGLLPGRKYYFRVVARNEIG------DSEPLDSRD 1185
A + + ++ + V+GL G Y +RV A N G EP+ +RD
Sbjct: 19263 KANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARD 19311
Score = 176 bits (447), Expect = 1e-43
Identities = 152/630 (24%), Positives = 264/630 (41%), Gaps = 70/630 (11%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ + E ++ + + WK P D+GG +T + VERR W++ +
Sbjct: 14200 PGPPE-KPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLR 14258
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVTKEAVT 819
++EG Y+FR+ A N G+ P E ++ V + PPG S P VTD TK++ +
Sbjct: 14259 CKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSAS 14318
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVP-VNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
+ W P DGG + GY+VE +K G W+ ++ T+ V L +Y FR+ A
Sbjct: 14319 LAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14378
Query: 879 VNKAGPGQPSV-PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPP----- 932
+N AG G+P+V P +V ++ L +L + + +S+ P +G P
Sbjct: 14379 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTW 14438
Query: 933 --SGYILEMRA--EDTKEWS-----KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV 983
L+ RA E+T+ ++ +C + T+ ++ F +R ++ G
Sbjct: 14439 TKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14498
Query: 984 G---EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK 1040
P ++ K + P D +R+ +++V +K
Sbjct: 14499 VLNLRPTDITKDSVTLHWDL-PLIDGGSRITNYIV-----------------------EK 14534
Query: 1041 DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPR 1097
K T T + + + +R++ +NE+G V+ ++ P
Sbjct: 14535 REATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS 14594
Query: 1098 PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKY 1154
PP +L + + +TV+L W P + DG + Y+I + + W T V +
Sbjct: 14595 PPDSLNIMDITKSTVSLAW---PKPKHDGGSKITGYVIEAQRKGSDQW-THITTVKGLEC 14650
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPR 1214
V L G +Y F+V+A N G S P +SR + + + +L + Y+K A
Sbjct: 14651 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLR-GIYQKLVIAKA-- 14707
Query: 1215 FVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPT 1274
G + + LG P+PTVT KGD + + + +T+ L I
Sbjct: 14708 ------------GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINE 14755
Query: 1275 CTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
C DSG Y + N +G+ T+ V+D
Sbjct: 14756 CVRSDSGPYPLTARNIVGEVGDVITIQVHD 14785
Score = 174 bits (442), Expect = 4e-43
Identities = 163/600 (27%), Positives = 259/600 (43%), Gaps = 61/600 (10%)
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L+A + ++ G T + VP +G+P PK+TW K + + + + ++ + L
Sbjct: 13323 LDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCE 13382
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
N + D+G +L L+N G T+ + VLD P PP V E+S ++ W+ P +
Sbjct: 13383 NVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVN-VTVKEISKDSAYVTWEPPIID 13441
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG P+ ++V++R +KSW + K T+F +EEGK+Y FR+ A N G+ DP
Sbjct: 13442 GGSPIINYVVQKRDAERKSWSTVTTECSK-TSFRVANLEEGKSYFFRVFAENEYGIGDPG 13500
Query: 789 ETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW 848
ET + + + PG +V V+K + +I W P DGG+ ++GY+V+ + N W
Sbjct: 13501 ETRDAVKAS--QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTE-ENKW 13557
Query: 849 VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL--- 905
V K + + L E EY FRV A N+ G G PS +VVA+D V P L
Sbjct: 13558 QRVMKS--LSLQYSAKDLTEGKEYTFRVSAENENGEGTPS--EITVVARDDVVAPDLDLK 13613
Query: 906 -VQDLHVSDSSNSSISLAWREPAEGDP-PSGYILEMRAEDTKEWSKCTKIPIS--GTCYT 961
+ DL NS+ L + P +G P PS + + ED + S T
Sbjct: 13614 GLPDLCYLAKENSNFRL--KIPIKGKPAPS--VSWKKGEDPLATDTRVSVESSAVNTTLI 13669
Query: 962 VGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAP-KFDLSARLKSHMVVRAGT 1020
V + + I N AG E K V P P KFD + A T
Sbjct: 13670 VYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFD-------EVTAEAMT 13722
Query: 1021 ALCIHAAFSGSPPPD---------VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSG 1071
+PP D ++ ++D V K T + + F +
Sbjct: 13723 -------LKWAPPKDDGGSEITNYILEKRDSVNNKW-VTCASAVQKTTFRVTRLHEGMEY 13774
Query: 1072 VYRILLQNEFG----------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+R+ +N++G AR+ V D P PP + + ++V+LTW
Sbjct: 13775 TFRVSAENKYGVGEGLKSEPIVARHPFD--VPDAPPPP---NIVDVRHDSVSLTWTDPKK 13829
Query: 1122 VQEDGEAHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
Y + ++ ++ W A + + + VTGL G +Y FRV+A N G +P
Sbjct: 13830 TGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKP 13889
Score = 174 bits (440), Expect = 7e-43
Identities = 143/479 (29%), Positives = 208/479 (43%), Gaps = 77/479 (16%)
Query: 743 VGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPP 802
V KKS + I VD K ++ T +E AVN G V N ++ P
Sbjct: 7370 VPKKSTVTI--VDSKRSDTGTYIIE----------AVNVCG-----RATAVVEVNVLDKP 7412
Query: 803 GFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCT 862
G + +TDVT E+ +TWN P DGG+ + Y+VERR S +W ++ ++ T
Sbjct: 7413 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSST-VKDTNFK 7471
Query: 863 VDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
L+ + EY FRV A N G G+P V +S + AK PPG L SD + +++L
Sbjct: 7472 ATKLIPNKEYIFRVAAENMYGVGEP-VQASPITAKYQFDPPGPPTRLEPSDITKDAVTLT 7530
Query: 923 WREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNE 980
W EP + G P +GY +E DT +W +C K+P+ T Y V GL ++KY FR+ A N
Sbjct: 7531 WCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENL 7590
Query: 981 AGVG------EPVELDKGVRAMPPPAAP-----------------KFDLSARLKSHMV-- 1015
AG G EP+ + + PP P + D A+++S+++
Sbjct: 7591 AGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEM 7650
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
++ GT + A +GVPT +Q L+ +R+
Sbjct: 7651 LKTGTDEWVRVA-------------EGVPT------------TQHLLPGLMEGQEYSFRV 7685
Query: 1076 LLQNEFGEARYD-----IHVRVADFP-RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH 1129
N+ GE+ + R +P PP L + NT L W +
Sbjct: 7686 RAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITN 7745
Query: 1130 YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWL 1188
YI+ KRD W T V K TVT L G Y FRV A N IG S+ + D+ L
Sbjct: 7746 YIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVL 7804
Score = 174 bits (440), Expect = 7e-43
Identities = 141/466 (30%), Positives = 208/466 (44%), Gaps = 32/466 (6%)
Query: 730 GRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFST-------NKVEEGKAYQFRILAVNSE 782
GRP + + V + +IG +D K T+F T NK + GK + + NS
Sbjct: 13347 GRPPPKITWSKPNVNLRD--RIG-LDIKSTDFDTFLRCENVNKYDAGK---YILTLENSC 13400
Query: 783 GVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRK 842
G + E ++ PG V +++K++ +TW P DGG+P++ Y+V++R
Sbjct: 13401 G-----KKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRD 13455
Query: 843 KGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKP 902
W V + T V L E Y FRV A N+ G G P +V A +
Sbjct: 13456 AERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKAS---QT 13511
Query: 903 PGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCY 960
PG V DL V S SS S+ W++P G GY+++ E+ K W + K Y
Sbjct: 13512 PGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKS--LSLQY 13568
Query: 961 TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGT 1020
+ L E ++Y FR+ A NE G G P E+ V A AP DL + + +
Sbjct: 13569 SAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENS 13626
Query: 1021 ALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
+ G P P V W+K D + T R ++ S ++ ++ ++SD+G Y I L+
Sbjct: 13627 NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLK 13686
Query: 1079 NEFGEARYDIHVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDA 1137
N G I ++V P PT F+EV +TL W D +YI+ KRD+
Sbjct: 13687 NVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13746
Query: 1138 STATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
W T A V + VT L G +Y FRV A N+ G E L S
Sbjct: 13747 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKS 13792
Score = 172 bits (437), Expect = 1e-42
Identities = 175/656 (26%), Positives = 265/656 (40%), Gaps = 95/656 (14%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG-----EVD 755
P PP G+ + L + + + W P DNGG P+T + +E+R G W ++ +V
Sbjct: 9227 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9285
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVT 814
K F+ ++ EG YQFR +A+N+ G+ P E ++ AG+PI PPG S P+V D T
Sbjct: 9286 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKT 9345
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLLEDTEY 872
K ++++ W P +DGG+P+ GYIVE +++G+ W VN+ I +C V L E +Y
Sbjct: 9346 KSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKY 9405
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA----E 928
FRV AVN+AG +PS + + A D + P + D+ D R PA
Sbjct: 9406 RFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGR 9465
Query: 929 GDPPSGYILEMRAE----------------DTKEWSKCTKIPISGTCYTVGGLIERQKYF 972
P S + + +A+ +T E S IP +T KY
Sbjct: 9466 PTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT-------GKY- 9517
Query: 973 FRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC--IHAAFSG 1030
I A N+AG + V+ M P PK LK + R L + G
Sbjct: 9518 -SITAKNKAG---QKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDDDGG 9568
Query: 1031 SPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG-------- 1082
+ +K + K + + F++ +R+ +N FG
Sbjct: 9569 DRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETI 9628
Query: 1083 ---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM-----K 1134
AR I+ P PP L++ NTV L+W + HYI+
Sbjct: 9629 QRTTARDPIYP-----PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDP 9683
Query: 1135 RDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQ 1193
W +R V ++TV L+ G +Y FRV A N G S+P
Sbjct: 9684 TGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP------------- 9730
Query: 1194 IQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNI 1253
SA + P + + P + + V G + + G P PT+T +K
Sbjct: 9731 ----SATVGPCDCQR-PDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKK 9785
Query: 1254 TANSKFWYNST-------SGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
N + T CTLVIP D+G Y++ N LG L V
Sbjct: 9786 PDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9841
Score = 172 bits (437), Expect = 1e-42
Identities = 178/792 (22%), Positives = 321/792 (40%), Gaps = 74/792 (9%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFI------A 599
W+K +E+++ ++I L G Y +AK E SV +
Sbjct: 16205 WIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDR 16264
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
P P V+ + A T+ K P + + + + E + ++
Sbjct: 16265 PGPPEGPVVISGVTAEKCTLAW------KPPLQDGGSDIINYIVERRETSRLVWTVVDAN 16318
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHG--------SATATLHLSVLDRPKPPQGRVEFL 711
++ + + + N +G A V D PK P E
Sbjct: 16319 VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP----EVT 16374
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK-----IGEVDGKVTNFSTNKV 766
++ + + W+ P +GG + +++E+R W + IGE+ +VT N
Sbjct: 16375 TVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH- 16433
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
Y+FR+ A N+ G+S+P A +PI PG + P+V D+T+ +V ++W+ P
Sbjct: 16434 ----DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKP 16489
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLEDTEYEFRVIAVNKAGP 884
DGG + GYIVE+ W I T V+ LLE EY FR+ A+NKAG
Sbjct: 16490 IYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGV 16549
Query: 885 GQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN--SSISLAWREPAEGDPPSGYILEMRAE 942
G+ + ++ ++ ++ P + DL + N + SL P +G P + + + +
Sbjct: 16550 GEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRP-TPEVKWGKVD 16608
Query: 943 DTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAP 1002
+ + S T + + + + N +G VR + P+ P
Sbjct: 16609 GEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVT---VRVLDTPSPP 16665
Query: 1003 KFDLSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
LK + + ++ GS + I +K K + + + + +
Sbjct: 16666 -----VNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSW 16720
Query: 1061 LINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWN 1117
I+ + S +R+ +NE+G A+ ++VA+ P+PP + + + N+V+L+W
Sbjct: 16721 KIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWT 16780
Query: 1118 HSPDVQEDGEAHYI--IMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEI 1175
+ DG + I I++ A + ++ RV S + +T L G +Y FRVVA NE
Sbjct: 16781 KP---EHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEK 16837
Query: 1176 GDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCA 1235
G S+P S ++ KD + + K P F + ++V GQD +
Sbjct: 16838 GRSDPR-SLAVPIVAKDLVIEPDVK------------PAFSS----YSVQVGQDLKIEVP 16880
Query: 1236 FLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDR 1295
G P+PT+T K + + ++ + + TL I D G Y + V N +G+
Sbjct: 16881 ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKT 16940
Query: 1296 SSCTLTVYDKDD 1307
+S + DK D
Sbjct: 16941 ASIEIVTLDKPD 16952
Score = 171 bits (432), Expect = 6e-42
Identities = 170/661 (25%), Positives = 275/661 (41%), Gaps = 101/661 (15%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP + ++++ V +KW+ PK++GGRP+ ++++E++ W+K G+ G N
Sbjct: 7812 PGPPYA-LAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 7870
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFA-GNPIEPPGFASQPQVTDVTKEAVT 819
F V EG QF++ A N GV P E E+ + +P PP VTD ++ +
Sbjct: 7871 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 7930
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVD-GLLEDTEYEFRVIA 878
I W P ++GG+P++GY VE G+ W+ VN PI+ K V+ G++ D EY RV A
Sbjct: 7931 IAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRA 7990
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGL---VQDLHVSDSSNSSISLAWREPAEGDPPSGY 935
VN G +PS S +VVAKDP P + D+ V + SI + +R A P +
Sbjct: 7991 VNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFR--AVPVPTVSW 8048
Query: 936 ILEMRAEDTKEWSKCTKIPISGTCYT----VGGLIERQKYFFRIRAVNEAGVGEPVELDK 991
+D KE ++ + + V + + I N+ G ++
Sbjct: 8049 -----HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG-SATASINV 8102
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA-FSGSPP--PDVIWQKDGVPTKGR 1048
V +P P +K+ + ++ L F G P V+ +++ GR
Sbjct: 8103 KVIGLPGPCKD-------IKASDITKSSCKLTWEPPEFDGGTPILHYVLERREA----GR 8151
Query: 1049 ET---ITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR---VADFPR----P 1098
T + +N + + + +R+ N+ G Y I ++ +A P+ P
Sbjct: 8152 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY-IELKNPVIAQDPKQPPDP 8210
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSN-KYT 1155
P ++ + +T+TW P + + G YII K W E + YT
Sbjct: 8211 PVDVEVHNPTAEAMTITWK--PPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYT 8268
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
GL G++Y FRV A N G SEP S P + D AP+
Sbjct: 8269 AKGLEEGKEYQFRVRAENAAGISEP-----------------SRATPPTKAVDPIDAPKV 8311
Query: 1216 V--TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWY------------ 1261
+ T L+ V RG + + + G+P PT+T K D N+ +
Sbjct: 8312 ILRTSLE---VKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE 8367
Query: 1262 ------------------NSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVY 1303
NS G L + D G Y + VEN+ G ++ CT++V
Sbjct: 8368 VQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8427
Query: 1304 D 1304
D
Sbjct: 8428 D 8428
Score = 169 bits (427), Expect = 2e-41
Identities = 217/939 (23%), Positives = 367/939 (39%), Gaps = 112/939 (11%)
Query: 430 VKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
VK R + ++ + T+ W+KDGQ L T+ +++ L I++A D G Y
Sbjct: 19034 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19093
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLA---TVKSGMSDVHAATGSPAEL---CVVLNDEKV 542
+ T IV + D + +P E C + N
Sbjct: 19094 ELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISN---- 19149
Query: 543 EGVWLKDGKEITDLPGMQIVKQGAVH---KLIFPSMGPEHEGKYTFR---AKGTESEASV 596
++ + KE T IV Q K++ + G E++ + K + SE+S
Sbjct: 19150 ---YIVEKKETTSTT-WHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSA 19205
Query: 597 FIADPPTIDPS------VLEA-----LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+A+ P P V+ A L + V G + I K + W K
Sbjct: 19206 VVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKAN 19265
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
+ + ++ + G D+ L+ E+ I G + + P P
Sbjct: 19266 KILIADTQMKVS-GLDEGLMYEYRVYAENIAGI--------GKCSKSCEPVPARDPCDPP 19316
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNK 765
G+ E ++ V +KW P +GG +T +IVERR + W+K + + T F +
Sbjct: 19317 GQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTE 19376
Query: 766 VEEGKAYQFRILAVNS-EGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDV--TKEAVTIT 821
+ E + Y+FR+ A N+ + VS+P E T + + +EPP + DV K +
Sbjct: 19377 LTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLK 19436
Query: 822 WNAPTQDGGAPVLGYI---VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
NA PV+ + +E ++ + + + K D + DT + +
Sbjct: 19437 INADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVK---DCIRRDTG---QYVL 19490
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYI 936
K G SV + V P P G L ++ + SL+W P E G YI
Sbjct: 19491 TLKNVAGTRSVAVNCKVLDKPGPPAG---PLEINGLTAEKCSLSWGRPQEDGGADIDYYI 19547
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
+E R W+ C + T V L++ +Y FR+ VN+ GVGEP+E ++A+
Sbjct: 19548 VEKRETSHLAWTICEG-ELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLE-SVAIKAL 19605
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT---- 1052
P P S + S V + LC P D + G + RE +
Sbjct: 19606 DPFTVPSPPTSLEITS--VTKESMTLCW-----SRPESDGGSEISGYIIERREKNSLRWV 19658
Query: 1053 --KSKNHSQFLINST--KRSDSGVYRILLQNEFG---EARYDIHVRVAD---FPRPPTNL 1102
K + ST + YR+ +N G + +R D P PP+
Sbjct: 19659 RVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKP 19718
Query: 1103 RLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYTVTGL 1159
++ + T+T+ W DG A Y + + + W T+ + + +YT++GL
Sbjct: 19719 KIVDSGKTTITIAWVKP---LFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGL 19775
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSRDTWLI---NKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
G +Y FRV + N++G S+P DS D + ++ + D+ ++++
Sbjct: 19776 TTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMR-------------- 19821
Query: 1217 TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
K V G TMT F G P P V K D ++ ++ + ++T +L I
Sbjct: 19822 ---KTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL--RTRAYVDTTDSRTSLTIENAN 19876
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASIT 1315
DSG Y++ ++N L +S TL V D +IT
Sbjct: 19877 RNDSGKYTLTIQNVL--SAASLTLVVKVLDTPGPPTNIT 19913
Score = 167 bits (424), Expect = 5e-41
Identities = 248/1114 (22%), Positives = 419/1114 (37%), Gaps = 162/1114 (14%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRM 317
P K+ W K LR + L D+K L NVN DAG Y L S G K
Sbjct: 13349 PPPKITWSKPNVNLRDRIGL---DIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEY 13405
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEP---------NFVWKFNGKELK 368
+ + VLD P PV VT ++ + ++ + P N+V + E K
Sbjct: 13406 TIVVKVLDTP------GPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERK 13459
Query: 369 R---------DDKYEITVSEDGLTHTLKI---KDARLSDSGEFSAEAGNLVQKAQLTIDR 416
+ + E+G ++ ++ + + D GE + +A Q +D
Sbjct: 13460 SWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGE-TRDAVKASQTPGPVVD- 13517
Query: 417 IPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKK---DGQLLMHGTKYSMNHEGKRA 473
+K RS + C ++ WKK DG + G E +
Sbjct: 13518 -------------LKVRSVSKSSC-------SIGWKKPHSDGGSRIIGYVVDFLTEENKW 13557
Query: 474 ELIIEDAQL-------SDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKS----GMSD 522
+ +++ L ++G EYT + + E + I V G+ D
Sbjct: 13558 QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPD 13617
Query: 523 VH--AATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHK-LIFPSMGPEH 579
+ A S L + + + V K G++ V+ AV+ LI
Sbjct: 13618 LCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSD 13677
Query: 580 EGKYTFRAKGT----ESEASVFIADPPTID--PSVLEALAAHAITVKVGHTAHIKVPFRG 633
GKYT K E S+ + P I P + + A A+T+K P +
Sbjct: 13678 AGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWA-------PPKD 13730
Query: 634 KPLPKVTWY-KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA--- 689
++T Y + + + V+ + ++ + +N +G
Sbjct: 13731 DGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGL 13790
Query: 690 -----TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVG 744
A V D P PP +++ V + W PK GG P+T + +E +
Sbjct: 13791 KSEPIVARHPFDVPDAPPPPN----IVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 13846
Query: 745 KKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP-LETEEVFAGNPIEPPG 803
W + + ++ +F + EG Y+FR++A+N GV P L +E V A +PI+PPG
Sbjct: 13847 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 13906
Query: 804 FASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTV 863
+P+V ++T+ +VT+ W P DGG + GYIVE+R S W+ N + TV
Sbjct: 13907 ---KPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTV 13963
Query: 864 DGLLEDTEYEFRVIAVNKAGP-GQPSVPSSSVVAKDPVKPPGLVQDLHVSD-----SSNS 917
L+E +YEFR+ A N AG PS + +++ KD + P +V D + D + ++
Sbjct: 13964 TDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDT 14023
Query: 918 SISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRA 977
+ A + P S + + + ++ T P S + T+ + + I A
Sbjct: 14024 IVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKDAGEYTITA 14082
Query: 978 VNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
N G E V++ V +P P P + + +A GSP
Sbjct: 14083 TNPFGTKVEHVKVT--VLDVPGPPGP-----VEISNVSAEKATLTWTPPLEDGGSPIKSY 14135
Query: 1037 IWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR--YDIHVRVAD 1094
I +K +++ + + + + ++R+ N +G+ V++ D
Sbjct: 14136 ILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVD 14195
Query: 1095 F---PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFS 1151
P PP + NT T++W D Y + +R+ + W A + S
Sbjct: 14196 RFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS 14255
Query: 1152 N-KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWR 1210
+ + VTGL G Y FRV A N G P ++ D+ L+ KD
Sbjct: 14256 DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLM-----------------KDAA 14298
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNIT--------ANSKFWYN 1262
+ P P PH D T A L +P Y G + IT + W
Sbjct: 14299 YPPG--PPSNPHVT----DTTKKSASLAWGKPH---YDGGLEITGYVVEHQKVGDEAWIK 14349
Query: 1263 STSG----VCTLVIPTCTLKDSGDYSVLVENELG 1292
T+G + V+P K+ ++ + N+ G
Sbjct: 14350 DTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14383
Score = 167 bits (423), Expect = 6e-41
Identities = 166/658 (25%), Positives = 277/658 (42%), Gaps = 63/658 (9%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
+++GA +KL ++ EG T +E +PP ++ L+ I +
Sbjct: 8694 IREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQ----EPPAVE---LDVSVKGGIQIMA 8746
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
G T I G+P+P W K+ E+ +++RV ++ ++ L I + +R+D G ++
Sbjct: 8747 GKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVIDNVGTKSELIIKDALRKDHGRYVIT 8805
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
N GS A + V D P P + C+ + W P+D+GG +T FI+ER+
Sbjct: 8806 ATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCL-LNWSDPEDDGGSEITGFIIERK 8864
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
+W + ++ + + + EG+ Y+FR++A N G P+E + A +P+ P
Sbjct: 8865 DAKMHTWRQ--PIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGP 8922
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
P + T+ TK +T+ W P +GG+P+ GYI+E+R+ + VNK T
Sbjct: 8923 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 8982
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
V+ L E YEFRV AVN+ G +PS+P + V+ D V PP + L V +I +
Sbjct: 8983 LVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEV-PPTIKLRLSV---RGDTIKV 9038
Query: 922 AWREPAEGDPPSGYILEMRAEDTKEWSK-------------CTKIPIS----GTCYTVGG 964
EP P L M EWSK TK +S T ++
Sbjct: 9039 KAGEPVH-IPADVTGLPM---PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPK 9094
Query: 965 LIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSAR---LKSHMVVRAGT 1020
+ K + + A N G V V ++ R PP D+ A L + G
Sbjct: 9095 AVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGG 9154
Query: 1021 ALCIHAAFSGSPPPDVIWQKDGVPTKGR-ETITKSKNHSQFLINSTKRSDSGVYRILLQN 1079
+ H VI ++D K E +T + ++ I + +R+ N
Sbjct: 9155 SEITHY---------VIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVN 9205
Query: 1080 EFG---EARYDIHVRVAD---FPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM 1133
++G E + D V + D P PP ++ ++ ++W D Y +
Sbjct: 9206 KYGISDECKSD-KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLE 9264
Query: 1134 KRDASTATWYTAAERVFSN------KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
KR+ + W + + ++ V LL G KY FR +A N G P + D
Sbjct: 9265 KREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSD 9322
Score = 165 bits (418), Expect = 2e-40
Identities = 271/1160 (23%), Positives = 436/1160 (37%), Gaps = 188/1160 (16%)
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMI-WIKGTEPLRIQYSLGKYDV 286
K++VEA++I K L++ VF +EL PNVK + WIK L S KY +
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFT--VELTHPNVKGVQWIKNGVVLE---SNEKYAI 2709
Query: 287 KQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAV 346
GT Y L I N + D +Y +G SA L V E +K + + K V E T
Sbjct: 2710 SVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHV--ETVKIIKKPKDVTALENATVA 2767
Query: 347 FEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
FE+ +S W E+K DK+ + VSE + H L +++ SD+GE++A G L
Sbjct: 2768 FEVSVSHDTVPVKWFHKSVEIKPSDKHRL-VSERKV-HKLMLQNISPSDAGEYTAVVGQL 2825
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
KA+L ++ + I +KN+ V E A ECE++ +V W K+G + K+ +
Sbjct: 2826 ECKAKLFVETLHI--TKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKI 2883
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
+GK +LII + D EYT V D +A +TV + T S + D++A
Sbjct: 2884 VVQGKLHQLIIMNTSTEDSAEYTFVCGND------QVSATLTVTPIMIT--SMLKDINAE 2935
Query: 527 TGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
V +N E + WLK+G EI Q+ + H L ++ YTF
Sbjct: 2936 EKDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFV 2995
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPL-------PKV 639
A S A++++ A H K H IKV + + + P +
Sbjct: 2996 AGKATSTATLYVE-------------ARHIEFRK--HIKDIKVLEKKRAMFECEVSEPDI 3040
Query: 640 T--WYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
T W KD E+ +R+ +++ + L I + D+G K G +T L V
Sbjct: 3041 TVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAG----KYTVVAGGNVSTAKLFV 3096
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
R R+ ++ + + R V +F V V W K DG
Sbjct: 3097 EGRDV----RIRSIKKEVQVIEKQ---------RAVVEFEVNEDDVDAH-WYK----DGI 3138
Query: 758 VTNFSTNKVEEGKAY----QFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDV 813
NF +V+E Y + + ++ SD E V N + + P+ V
Sbjct: 3139 EINF---QVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQV 3195
Query: 814 TKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE 873
+E +T Q G ++ R + W + G KC L + EY
Sbjct: 3196 LQELQPVT----VQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKF--LHDGQEYT 3249
Query: 874 FRVI-------------AVNKAGPGQPSVPSS----SVVAKD---PVKPPGLV---QDLH 910
+I A N G S S VV+ D PV PP ++ QD
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3309
Query: 911 VSDS---------SNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT 961
S+ S + + ++W + PS + + EDT + P YT
Sbjct: 3310 TSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYT 3369
Query: 962 ---------VGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKS 1012
V F N + V L + P P F + S
Sbjct: 3370 FVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSF---IQPLS 3426
Query: 1013 HMVVRAGTALCIHAAFSGSPPPDVIW---QKDGVPTKGRET-ITKSKNHSQFLINSTKRS 1068
+ V G + HA SG P P++ W Q+ +PTK +S + LI
Sbjct: 3427 SLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSE 3486
Query: 1069 DSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA 1128
+G Y N GEA + V P+ P ++ L E + + +
Sbjct: 3487 HAGQYSCKAANSAGEATCAATLTVT--PKAPESI-LHERIEQEIEME------------- 3530
Query: 1129 HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWL 1188
MK +S+ + +AE E L S + L
Sbjct: 3531 ----MKEFSSS---FLSAEE------------------------------EGLHSAELQL 3553
Query: 1189 INKDQIQDLSAKLKPYEKKDWRH----APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTV 1244
++ +L ++ Y K P F+ + + G T++ +G P+P +
Sbjct: 3554 SKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKI 3613
Query: 1245 TLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
+ V +T ++ + + +L+I L+D G+Y+ + N+ GK S L +
Sbjct: 3614 QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3673
Query: 1305 K----DDKSVVASITESLQK 1320
K D +++ +SL+K
Sbjct: 3674 KGEGHKDTETESAVAKSLEK 3693
Score = 165 bits (417), Expect = 3e-40
Identities = 163/635 (25%), Positives = 271/635 (42%), Gaps = 78/635 (12%)
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
+D +PP+ V ++S + V + W+ P +GG +T +IVERR + W K +
Sbjct: 20393 IDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20451
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEG-------VSDPLETEEVFAGNPIEPPGFASQPQV 810
T F + + + Y+FR+ A N+ G V P+ + + G I+ P +
Sbjct: 20452 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLP-----LEY 20506
Query: 811 TDVTK--EAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
T+V K ++ A AP + + + ++ +N V V + T L++
Sbjct: 20507 TEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCV-----ENTTDLASILIK 20561
Query: 869 DTE------YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
D + YE ++ N G ++ V D PPG + + I+L
Sbjct: 20562 DADRLNSGCYELKLR--NAMGSASATI---RVQILDKPGPPG--GPIEFKTVTAEKITLL 20614
Query: 923 WREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNE 980
WR PA+ G + YI+E R WS ++ + T +I+ +Y FR+RAVN+
Sbjct: 20615 WRPPADDGGAKITHYIVEKRETSRVVWSMVSE-HLEECIITTTKIIKGNEYIFRVRAVNK 20673
Query: 981 AGVGEPVELDKGV--RAMPPPAAPKF-DLSARLKSHMVVRAGTALCIHAAFSGSPPPDVI 1037
G+GEP+E D V A P P +++ K+ M V + A GS
Sbjct: 20674 YGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPI----ADGGSDISGYF 20729
Query: 1038 WQKDGVPTKGRETITKS--KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV--- 1092
+K + G + K ++ Q + T+ SD YR+ N G+ +
Sbjct: 20730 LEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKA 20788
Query: 1093 ---ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAE 1147
D P PP +R+ + +++TL W S V + G A Y++ R W T +
Sbjct: 20789 ADPIDPPGPPAKIRIADSTKSSITLGW--SKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20846
Query: 1148 R--VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYE 1205
+ V + +Y V+ L PG YYFRV A N G EP++ + P +
Sbjct: 20847 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNE-----------------PVQ 20889
Query: 1206 KKDWRHAPRFVTPLKPHTVL---RGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
KD AP + T + G+D + F G P PTVT K + N+ +++++
Sbjct: 20890 AKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE 20949
Query: 1263 STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSS 1297
+T L IP T D+G Y + +EN +G+ +SS
Sbjct: 20950 NTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSS 20984
Score = 165 bits (417), Expect = 3e-40
Identities = 205/927 (22%), Positives = 345/927 (37%), Gaps = 119/927 (12%)
Query: 441 ELTSKDVTLRWK---KDGQLLMHGTKYSMN-HEGKRAELIIEDAQLSDGGEYTVVAMQDG 496
++T + +TL+W +DG + G YS+ +G + +S+ +YTV + G
Sbjct: 21493 DVTRETITLKWNPPLRDGGSKIVG--YSIEKRQGNERWVRCNFTDVSEC-QYTVTGLSPG 21549
Query: 497 D----------------PTEYYSTAIVTVEERLATV----KSGMSDVHAATGSPAELCVV 536
D P S I+T +E + + + +G + +
Sbjct: 21550 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 21609
Query: 537 LNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT----E 591
+ V V W KDG EI M+I L +H G YT AK +
Sbjct: 21610 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 21669
Query: 592 SEASVFIADPP--TIDPSVLEALAAHAITV------KVGHTAHIKVPFRGKPLPKVTW-- 641
+E V + D P + P + +T+ G + ++ W
Sbjct: 21670 AEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWAL 21729
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP 701
+D E + + G + +S + G L D A + +V D P
Sbjct: 21730 IEDKCEAQSYTAIKLINGNEYQF-RVSAVNKFGVGRPL-----DSDPVVAQIQYTVPDAP 21783
Query: 702 KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK-IGEVDGKVTN 760
P+ ++G+ + + W P+ +GG + Q+I+ERR W+K I + T
Sbjct: 21784 GIPEPS----NITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETR 21839
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVT 819
F + EG Y+F ++A N+ GV + P+ PPG + +VTD +K V+
Sbjct: 21840 FKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVS 21899
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAV 879
+ W+ P DGG ++GYI+E K W VN + T+ TV L EY+FRV A+
Sbjct: 21900 LEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAI 21959
Query: 880 NKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDS----SNSSISL------------AW 923
N AG G + ++ A D + P L D + + + +SI L W
Sbjct: 21960 NGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVW 22019
Query: 924 REPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV 983
+P I + T C + TV + F ++ ++ G
Sbjct: 22020 SKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP 22079
Query: 984 GEPVELDKGVRAMPPPA--APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKD 1041
P+ R AP D AR+ ++V +K
Sbjct: 22080 PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVV-----------------------EKR 22116
Query: 1042 GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR-YDIH--VRVADFPRP 1098
+ + I++ F +N +R+ NE+G Y++ + + P P
Sbjct: 22117 EASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP 22176
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYT 1155
P L + + ++ L W PD DG + Y++ R + W A +T
Sbjct: 22177 PRRLDVVDTSKSSAVLAWL-KPD--HDGGSRITGYLLEMRQKGSDFWVEAGHTK-QLTFT 22232
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
V L+ +Y FRV A+N+ G SEP ++ + +I + QI+ +A L
Sbjct: 22233 VERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP-TADLTGITN--------- 22282
Query: 1216 VTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
+ T G T+ G P P VT ++ + + +T TL +
Sbjct: 22283 ----QLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 22338
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTV 1302
DSG Y + +EN G S T+ V
Sbjct: 22339 MRGDSGRYFLTLENTAGVKTFSVTVVV 22365
Score = 164 bits (416), Expect = 4e-40
Identities = 230/1109 (20%), Positives = 416/1109 (37%), Gaps = 125/1109 (11%)
Query: 268 WIKGTEPLRIQYSLGKYDVKQMGT------KYMLVISNVNMNDAGIYSL----SVGDKRM 317
++ G P + +++ + + Q T +VI N + G+YSL G+++
Sbjct: 10175 YVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKK 10234
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDK----- 372
+ + VLD P +T + + + + ++ + D +
Sbjct: 10235 TIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPV 10294
Query: 373 -YEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVK 431
Y +T + ++ K + E S G V+ ++ + R PI +++ VK
Sbjct: 10295 TYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVK 10354
Query: 432 ERSRACLECELTSKDVTLRWKKD----GQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGE 487
E +T VTL W G +++ S ++ + D LS +
Sbjct: 10355 E---------VTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSR--K 10403
Query: 488 YTVVAMQDGDPTEYYSTAI--------------VTVEERLA------------TVKSGMS 521
YTV +++GD EY +A+ +T ++ LA T++ G
Sbjct: 10404 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVG-- 10461
Query: 522 DVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEG 581
+ A TG + K + W KD ++ + I A L G
Sbjct: 10462 EAFALTGRYS------GKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSG 10515
Query: 582 KYTFRAKGTES------EASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKP 635
KY + + + +V P + P + + + + K P
Sbjct: 10516 KYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISW------KPPLDDGG 10569
Query: 636 LPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLH- 694
+ + EV ++ + + + +S + + + +N +G + +
Sbjct: 10570 SKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSD 10629
Query: 695 -LSVLDRPKPPQGRVEFL--ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKI 751
+ DR + P + + E++ + W P D GG+P+T +I+E+R K W ++
Sbjct: 10630 SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARV 10688
Query: 752 GEVD-GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQ 809
+ T F + EG Y+FR+ A N G+ DP ++ VFA +PI P P+
Sbjct: 10689 TKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPE 10748
Query: 810 VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLL 867
D T +V +TW P DGG+ +LGYIVE +K G W N P TK V GL
Sbjct: 10749 AIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLR 10808
Query: 868 EDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA 927
+ Y+FRV+AVN AG P+ V+ KD ++PP L+ D +++ + + R A
Sbjct: 10809 DGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSA 10868
Query: 928 --EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
+G P + D ++ P+ G+ + + + N AG
Sbjct: 10869 IIKGVPFPKVTWKKEDRDAPTKARIDVTPV-GSKLEIRNAAHEDGGIYSLTVENPAG--- 10924
Query: 986 PVELDKGVRAMPPPAAPK-FDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP 1044
+ V + P P+ ++S K + L GS + + ++ V
Sbjct: 10925 SKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPL----DDGGSVITNYVVERRDVA 10980
Query: 1045 TKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY---DIHVRVADF---PRP 1098
+ ++ + + ++R+ +N++G + ++ D P P
Sbjct: 10981 SAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGP 11040
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYT 1155
P +L + V+L WN PD DG + Y++ ++ T W + V + +
Sbjct: 11041 PKDLHHVDVDKTEVSLVWN-KPD--RDGGSPITGYLVEYQEEGTQDWIKF-KTVTNLECV 11096
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
VTGL G+ Y FRV A N +G P D + ++ EK
Sbjct: 11097 VTGLQQGKTYRFRVKAENIVGLGLP---------------DTTIPIECQEKLVPPSVELD 11141
Query: 1216 VTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
V ++ V G G P PT I + + + + L I C
Sbjct: 11142 VKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNC 11201
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
+D+G+Y + V N G + LTV D
Sbjct: 11202 LRRDTGEYQITVSNAAGSKTVAVHLTVLD 11230
Score = 163 bits (412), Expect = 1e-39
Identities = 149/604 (24%), Positives = 259/604 (42%), Gaps = 43/604 (7%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
I + P ID L+ ++ K G + +PF+G+P P VTW KD + + R S+E
Sbjct: 20893 ILEAPEID---LDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE 20949
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGS-ATATLHLSVLDRPKPPQGRVEFLELSGS 716
+ +LLTI R D+G +L ++N G ++T+ + VLD P Q +++ +S
Sbjct: 20950 NTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQ-KLQVKHVSRG 21008
Query: 717 CVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRI 776
V + W P +GG P+ +++E+R K++W + T+F + E + FR+
Sbjct: 21009 TVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSS-TSFKLIDLSEKTPFFFRV 21067
Query: 777 LAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGY 836
LA N G+ +P ET E E P + D TK +V ++W P DGG+ + Y
Sbjct: 21068 LAENEIGIGEPCETTEPV--KAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY 21125
Query: 837 IVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVA 896
+VER+ KG W + + V L E + EFRV A N+ G P V +
Sbjct: 21126 VVERKGKGEQTWSHAGIS--KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP-VTIGPITV 21182
Query: 897 KDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPIS 956
K+ + P ++ +SD + +++ + P + + + + W K +P+
Sbjct: 21183 KELIITP----EVDLSDIPGAQVTVRIGHNVHLELP----YKGKPKPSISWLK-DGLPLK 21233
Query: 957 GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV--RAMP-------PPAAPKFDLS 1007
+ + E + A E G V LD V A+P PP+ PK +
Sbjct: 21234 ESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIR 21293
Query: 1008 -ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTK 1066
+K+ V+ + + G +K + + S + F + +
Sbjct: 21294 FDEIKADSVILSWD---VPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLV 21350
Query: 1067 RSDSGVYRILLQNEFGEAR---YDIHVRVADF--PRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+ +R+ +N +G ++ I V F P PP ++ + ++LTW+
Sbjct: 21351 KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWD--AP 21408
Query: 1122 VQEDGE--AHYIIMKRDASTATWYTA-AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
V + G + + K++ ++ W + +Y TGL+ G Y FRV A N G S
Sbjct: 21409 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21468
Query: 1179 EPLD 1182
P D
Sbjct: 21469 SPSD 21472
Score = 162 bits (409), Expect = 3e-39
Identities = 153/668 (22%), Positives = 271/668 (40%), Gaps = 55/668 (8%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+F+ + VTA E + AVF + + + W + + + + K H +
Sbjct: 5558 KFLTPLKDVTAKEKESAVFTVELSHD-NIRVKWFKNDQ-RLHTTRSVSMQDEGKTHSITF 5615
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTV---------SLLVTEGQEKMDF------------ 166
+ L+ DD+ + A ++A TV L G EK +
Sbjct: 5616 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5675
Query: 167 KKMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMK 226
K K P K A+ K+ + IL K K D + + G G K
Sbjct: 5676 VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDKTSG--------K 5727
Query: 227 KKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIW-IKGTEPLRIQYSLGKYD 285
+E I++++PL E T F+ E+ + ++ W +KG L+ +
Sbjct: 5728 LDIEDREIKLVRPLHSVEVMETETARFET--EISEDDIHANWKLKGEALLQTP----DCE 5781
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
+K+ G + LV+ N ++ G + + SA L V + L +K V VT +TA
Sbjct: 5782 IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETA 5841
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
F+ LS ++ W GK+L+ DK + +G HTL ++D +L D+GE A +
Sbjct: 5842 TFDCELSYEDIPVEWYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5899
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
A L + P++F L++ V+E + A LECE++ ++ ++W K+G ++ KY
Sbjct: 5900 FKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYE 5959
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ +G+ +L+I D D YT D ++ ++ + V ++D+
Sbjct: 5960 IVADGRVRKLVIHDCTPEDIKTYTC------DAKDFKTSCNLNVVPPHVEFLRPLTDLQV 6013
Query: 526 ATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A L+ E + W KDG EI I+ +GAV L+ + E +Y+
Sbjct: 6014 REKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC 6073
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFR-GKPLPKVTWYKD 644
+ + + + + + + ++V T IK+ KP +V WYK
Sbjct: 6074 EVRTARTSGMLTVLEEEAV-------FTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKG 6126
Query: 645 GMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
E+ E R + + +L I N ED+G +L + +H + P
Sbjct: 6127 DEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKP 6186
Query: 705 QGRVEFLE 712
Q +E LE
Sbjct: 6187 Q-NLEILE 6193
Score = 160 bits (406), Expect = 6e-39
Identities = 256/1157 (22%), Positives = 432/1157 (37%), Gaps = 180/1157 (15%)
Query: 242 DKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVN 301
++ KV T+ I++ P K+ W K R + + DV +G+K L I N
Sbjct: 10855 EQHIKVGDTLRLSAIIK-GVPFPKVTWKKED---RDAPTKARIDVTPVGSK--LEIRNAA 10908
Query: 302 MNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMKPVKVTE-RQTAVFEIRLSKKEP 356
D GIYSL+V G K +S ++ VLD+P G + ++V+E R+ + + L+ KEP
Sbjct: 10909 HEDGGIYSLTVENPAGSKTVSVKVLVLDKP----GPPRDLEVSEIRKDSCY---LTWKEP 10961
Query: 357 ---------NFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGE---FSAEAG 404
N+V ++R D S T K A+ + G F A
Sbjct: 10962 LDDGGSVITNYV-------VERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 11014
Query: 405 NLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKK---DGQLLMHG 461
N + PIK + L + ++ +V+L W K DG + G
Sbjct: 11015 NQYGRGPFVETPKPIKALDPL---HPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITG 11071
Query: 462 TKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYY-------------STAIVT 508
EG + + + E V +Q G + +T +
Sbjct: 11072 YLVEYQEEGTQDWIKFKTV---TNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIE 11128
Query: 509 VEERLATVKSGM-----SDVHAATGSPAELCVVLNDEKV-EGVWLKDGKEITDLPGMQIV 562
+E+L + + G+ ++ V W DG EI +
Sbjct: 11129 CQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE 11188
Query: 563 KQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVF-------IADPPTIDPSVLEALAAH 615
L + G+Y +V + PPT ++L+ H
Sbjct: 11189 TDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEH 11248
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDS 675
T + P P + + + + ++ + G + L I + +
Sbjct: 11249 M-------TISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCE 11301
Query: 676 GLILLKLKNDHG-----SATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGG 730
+ ++ +N G +T T+ P PP G+ +++ + + W PK +GG
Sbjct: 11302 YVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPP-GKPVVTDITENAATVSWTLPKSDGG 11360
Query: 731 RPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL-E 789
P+T + +ERR V K W+++ + F + EG Y+FR+ A N G+S P
Sbjct: 11361 SPITGYYMERREVTGK-WVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 11419
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
++ + A PI+PPG P++ D ++E + W P DGG+P+LGY+VE +K G+ W
Sbjct: 11420 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWN 11479
Query: 850 PVNKDP-IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQD 908
+NKD I+ V GL+E EY FR+ A N G G+P + SV+AKD + PP + D
Sbjct: 11480 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 11539
Query: 909 LHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ D + R A ++ R E W+K G ++ R
Sbjct: 11540 VTCRDVITVRVGQTIRILAR--------VKGRPEPDITWTK------------EGKVLVR 11579
Query: 969 QKYFFRIRAVN--EAGVGEPVELDKGVRAMPPPAAPKFDLSARLKS---------HMVVR 1017
+K I+ + E + E V D G K+ +SA+ S +++ R
Sbjct: 11580 EKRVDLIQDLPRVELQIKEAVRADHG----------KYIISAKNSSGHAQGSAIVNVLDR 11629
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT---------KSKNHSQFLINSTKR- 1067
G + + W+ G IT K S + TKR
Sbjct: 11630 PGPCQNLKVTNVTKENCTISWENP--LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRL 11687
Query: 1068 -------SDSGVYRILLQNEFG-----EARYDI-HVRVADFPRPPTNLRLFEEVPNTVTL 1114
++ +R+ +N+ G E + I + D P P NL + ++ V L
Sbjct: 11688 IKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYL 11747
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAE-RVFSNKYTVTGLLPGRKYYFRVVARN 1173
W Y + +R + W + + Y V + + Y FRV +N
Sbjct: 11748 KWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKN 11807
Query: 1174 EIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPH---TVLRGQDC 1230
E G+S+ + + + ++ K+ +Q KP V LK TV G
Sbjct: 11808 EGGESDWVKTEE--VVVKEDLQ------KP------------VLDLKLSGVLTVKAGDTI 11847
Query: 1231 TMTCAFLGNPRPTV--TLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVE 1288
+ G P P V T K ++T + + ++ + + D G Y V
Sbjct: 11848 RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTAT 11907
Query: 1289 NELGKDRSSCTLTVYDK 1305
N G + T+ V DK
Sbjct: 11908 NTAGSFVAYATVNVLDK 11924
Score = 160 bits (406), Expect = 6e-39
Identities = 157/655 (23%), Positives = 275/655 (41%), Gaps = 61/655 (9%)
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDR-----PKPPQGRVEFLELSG 715
++ ++T + ++ + + ++ N +G SV+ + P PP G E +++
Sbjct: 20649 EECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITK 20707
Query: 716 SCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFR 775
+ + + W P +GG ++ + +E+R W K+ + + T + E YQ+R
Sbjct: 20708 NSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYR 20767
Query: 776 ILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVL 834
+ AVN+ G E E + A +PI+PPG ++ ++ D TK ++T+ W+ P DGG+ V
Sbjct: 20768 VCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 20827
Query: 835 GYIVERRKKGSNLWVPVN-KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSS 893
GY+VE R+ W V+ K ++ T+ V L Y FRV AVN AG G+P +
Sbjct: 20828 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 20887
Query: 894 VVAKDPVKPPGLVQD--LHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCT 951
V AKD ++ P + D L S + + + P +G PP +D K
Sbjct: 20888 VQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWR---KDEKNLGSDA 20944
Query: 952 KIPISGT----CYTVGGLIERQ--KYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFD 1005
+ I T T+ + KY I E GVGEP V+ + PAA +
Sbjct: 20945 RYSIENTDSSSLLTIPQVTRNDTGKYILTI----ENGVGEPKSSTVSVKVLDTPAACQ-- 20998
Query: 1006 LSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLIN 1063
+L+ V R L GSP + + +K + ++ + + F +
Sbjct: 20999 ---KLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI 21055
Query: 1064 STKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
+R+L +NE G V+ A+ P P +L + + +V L+W P
Sbjct: 21056 DLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWT-KP 21114
Query: 1121 DVQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGD 1177
D DG + Y++ ++ TW A + + V+ L FRV A+NE G
Sbjct: 21115 DF--DGGSVITEYVVERKGKGEQTWSHAGISK-TCEIEVSQLKEQSVLEFRVFAKNEKGL 21171
Query: 1178 SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT---PLKPHTVLRGQDCTMTC 1234
S+P+ + P K+ P P TV G + +
Sbjct: 21172 SDPVT------------------IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLEL 21213
Query: 1235 AFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVEN 1289
+ G P+P+++ K + + + ++ T TL I + G Y+V+++N
Sbjct: 21214 PYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN 21268
Score = 154 bits (389), Expect = 5e-37
Identities = 157/664 (23%), Positives = 267/664 (40%), Gaps = 60/664 (9%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+ ++KP+ VTA E F V + P + W +S + IK S K S K H L L
Sbjct: 2750 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKS-VEIKPSDKHRLVSERKVHKLML 2807
Query: 128 EPLTSDDSDNYKCIASNDHADA-IYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
+ ++ D+ Y + A ++ +L +T+ + ++ P+ K
Sbjct: 2808 QNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKNIE-----------VPETKTASFE 2856
Query: 187 NEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVE---------------- 230
E + S K E E +G L +L M E
Sbjct: 2857 CEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSA 2916
Query: 231 ---VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
V I I L+D + T+ F+ + + + K W+K ++ S K ++
Sbjct: 2917 TLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYK--WLKNGVEIK---STDKCQMR 2971
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+ L I NV+ DA Y+ G +A L V ++F +K +KV E++ A+F
Sbjct: 2972 TKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMF 3031
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E +S+ + W + +EL+ D+ I + ++ H L I R+SD+G+++ AG V
Sbjct: 3032 ECEVSEPDITVQWMKDDQELQITDR--IKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNV 3089
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A+L ++ ++ S K V+V E+ RA +E E+ DV W KDG + +
Sbjct: 3090 STAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3149
Query: 468 H--EGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ E + + I + + SD GEYT VA ++ Y A V + V
Sbjct: 3150 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNA-----PEPPQVLQELQPVTV 3204
Query: 526 ATGSPAELCVVLNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
+G PA C V++ + W K+ + ++ + + G + L+ PE YT
Sbjct: 3205 QSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYT 3264
Query: 585 FRAKG----TESEASVFIADPPTIDPSVLEALAAHAITVKV-------GHTAHIKVPFRG 633
AK + AS+ + P + P + AI + G A + G
Sbjct: 3265 CEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG 3324
Query: 634 KPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
L KV+WY ++ M + ED L I+ ED G N G ++T
Sbjct: 3325 TDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTA 3383
Query: 694 HLSV 697
+LS+
Sbjct: 3384 NLSL 3387
Score = 152 bits (385), Expect = 2e-36
Identities = 151/601 (25%), Positives = 256/601 (42%), Gaps = 58/601 (9%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+ P ID L+ I ++ G + + VP +G+P P+V W K E+ + + +
Sbjct: 16566 EAPDID---LDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSS 16622
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
L + N R DSG L L+N G+ +A + + VLD P PP ++ E++ V
Sbjct: 16623 FTS--LVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVN-LKVTEITKDSVS 16679
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTN-----KVEEGKAYQF 774
+ W+ P +GG + +IVE+R +KS+ + VTN N +++EG +Y F
Sbjct: 16680 ITWEPPLLDGGSKIKNYIVEKREATRKSYAAV------VTNCHKNSWKIDQLQEGCSYYF 16733
Query: 775 RILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPV 833
R+ A N G+ P +T + + +PPG + V DVT+ +V+++W P DGG+ +
Sbjct: 16734 RVTAENEYGIGLPAQTADPIKVAEVPQPPGKIT---VDDVTRNSVSLSWTKPEHDGGSKI 16790
Query: 834 LGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSS 893
+ YIVE + K S W + ++ + + L + EY FRV+AVN+ G P +
Sbjct: 16791 IQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP 16848
Query: 894 VVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKI 953
+VAKD V P V+ S S L P G P +D + T+I
Sbjct: 16849 IVAKDLVIEPD-VKPAFSSYSVQVGQDLKIEVPISGRPKPTITW---TKDGLPLKQTTRI 16904
Query: 954 PISGTC-YTVGGLIERQK---YFFRIRAVNEAGVG----EPVELDKGVRAMPPPAAPKFD 1005
++ + T + E K + I N G E V LDK PP KFD
Sbjct: 16905 NVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK---PDPPKGPVKFD 16961
Query: 1006 ----LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
S L + + G G + I QK T + ++ + +
Sbjct: 16962 DVSAESITLSWNPPLYTG----------GCQITNYIVQKRDTTTTVWDVVSATVARTTLK 17011
Query: 1062 INSTKRSDSGVYRILLQNEFGEA-RYDIHVRVADF----PRPPTNLRLFEEVPNTVTLTW 1116
+ K +RI +N +G++ + VA + P PP +++ + W
Sbjct: 17012 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 17071
Query: 1117 NHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGRKYYFRVVARNEI 1175
+ + Y + +++ ++ W + + ++ L G +Y FRV A N +
Sbjct: 17072 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIV 17131
Query: 1176 G 1176
G
Sbjct: 17132 G 17132
Score = 151 bits (381), Expect = 5e-36
Identities = 228/1018 (22%), Positives = 388/1018 (38%), Gaps = 103/1018 (10%)
Query: 224 EMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQY---- 279
EM + V+ + I LE E +D + I + + +I KG P + +
Sbjct: 20883 EMNEPVQAKDI-----LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDE 20937
Query: 280 ----SLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGD-----KRMSAELTVLDEPLKF 330
S +Y ++ + +L I V ND G Y L++ + K + + VLD P
Sbjct: 20938 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 20997
Query: 331 LGEMKPVKVTERQTAVFE-----IRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHT 385
+ VK R T I N+V +++ D + T S ++H
Sbjct: 20998 --QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYV-------IEKRDATKRTWSV--VSHK 21046
Query: 386 LKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSK 445
+L D E + ++ + ++ I P + +K V R + T
Sbjct: 21047 CSSTSFKLIDLSEKTPFFFRVLAENEIGIGE-PCETTEPVKAAEVPAPIRDLSMKDSTKT 21105
Query: 446 DVTLRWKK---DGQLLMHGTKYSMNHEGKRAELI----------IEDAQLSDGG--EYTV 490
V L W K DG ++ T+Y + +GK + IE +QL + E+ V
Sbjct: 21106 SVILSWTKPDFDGGSVI--TEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRV 21163
Query: 491 VAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT-----GSPAELCVVLNDEKVEGV 545
A + ++ + +TV+E + T + +SD+ A G L + + +
Sbjct: 21164 FAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI 21223
Query: 546 -WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIA----D 600
WLKDG + + ++ K L + EH GKYT +V I
Sbjct: 21224 SWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLG 21283
Query: 601 PPT--IDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME- 657
PP+ P + + A ++ + VP ++T Y T + M
Sbjct: 21284 PPSKPKGPIRFDEIKADSVILS------WDVP-EDNGGGEITCYSIEKRETSQTNWKMVC 21336
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDR-----PKPPQGRVEFLE 712
+ + N V++ ++ +N +G + + ++ + P PP G+
Sbjct: 21337 SSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GKPVIYN 21395
Query: 713 LSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAY 772
++ + + W AP +GG VT F VE++ W K+ + + EG Y
Sbjct: 21396 VTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDY 21455
Query: 773 QFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA 831
QFR+ A NS G+S P + + A +P++PPG P DVT+E +T+ WN P +DGG+
Sbjct: 21456 QFRVYAENSAGLSSPSDPSKFTLAVSPVDPPG---TPDYIDVTRETITLKWNPPLRDGGS 21512
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGP-GQPSVP 890
++GY +E+R +G+ WV N + + TV GL YEFR+IA N G PS
Sbjct: 21513 KIVGYSIEKR-QGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQS 21571
Query: 891 SSSVVAKDPVKPPGLVQDLHVSDS--SNSSISLAWREPAEGDP-PSGYILEMRAEDTKEW 947
S ++ +D PP + D S SL + +G P P + E K
Sbjct: 21572 SGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM 21631
Query: 948 SKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLS 1007
+ + T V + + + A N +G + E+ V+ P +
Sbjct: 21632 NMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK-AEIKVKVQDTPGKVVGPIRFT 21690
Query: 1008 ARLKSHMV------VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE-TITKSKNHSQF 1060
M + G A H + W + + T K N +++
Sbjct: 21691 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEY 21750
Query: 1061 LINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
+ + GV R L + I V D P P + N++TLTW
Sbjct: 21751 QFRVSAVNKFGVGRPL---DSDPVVAQIQYTVPDAPGIPEPSNI---TGNSITLTWARPE 21804
Query: 1121 DVQEDGEAHYIIMKRDASTATWYTAAER--VFSNKYTVTGLLPGRKYYFRVVARNEIG 1176
YI+ +R+ + W + + ++ VTGL G +Y F V+A N G
Sbjct: 21805 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 21862
Score = 147 bits (371), Expect = 7e-35
Identities = 156/631 (24%), Positives = 257/631 (40%), Gaps = 77/631 (12%)
Query: 702 KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNF 761
KP RV + + + V + W P+D GG VT +++E + V + W K K+ +
Sbjct: 23663 KPQNPRVT--DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREY 23720
Query: 762 STNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGFASQPQVTD--VTKEAV 818
+ + +G Y+FR+LA N+ G +P E V +E P + + + ++
Sbjct: 23721 TLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGG 23780
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN--------KDPIQGTKCTVDGLLEDT 870
I P + P+ + E + + + K+ +G T D +LE
Sbjct: 23781 VIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLE-- 23838
Query: 871 EYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE-- 928
NK G + +V V P P G L D S+ ++WR PA+
Sbjct: 23839 ---------NKCG--KKAVYIKVRVIGSPNSPEG---PLEYDDIQVRSVRVSWRPPADDG 23884
Query: 929 GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE 988
G GYILE R W + GT V GL E +Y FR+ A N+ G+ +P++
Sbjct: 23885 GADILGYILERREVPKAAWYTIDS-RVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLK 23943
Query: 989 LDKGVRAMPP--PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPT 1045
++ V P P P + L V ++ +L S S P D + G
Sbjct: 23944 SEEPVTPKTPLNPPEPPSNPPEVLD---VTKSSVSL------SWSRPKDDGGSRVTGYYI 23994
Query: 1046 KGRETIT-KSKNHSQFLINSTKRSDSGV-------YRILLQNEFGEARYD------IHVR 1091
+ +ET T K H++ I +T + +G+ +RI+ QN+ G + +
Sbjct: 23995 ERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 24054
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA-HYIIMKRDASTATWYTA-AERV 1149
D P P L + ++VTL W P+ E Y + R + + W + ER+
Sbjct: 24055 PFDKPSQPGELEILSISKDSVTLQWE-KPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 24113
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
++T+ GLL +Y FRV A NE G S P + + KL E
Sbjct: 24114 KDKQFTIGGLLEATEYEFRVFAENETGLSRP----------RRTAMSIKTKLTSGE---- 24159
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
AP +K T G+ ++C +G P P + Y+ + + K+ +S T
Sbjct: 24160 --APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT 24217
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
L + T +D G Y+ + NE+G+ +S L
Sbjct: 24218 LTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24248
Score = 146 bits (368), Expect = 1e-34
Identities = 152/685 (22%), Positives = 274/685 (40%), Gaps = 60/685 (8%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+F + VT PE +A F + A ++ W + I IK S K + K+H+L +
Sbjct: 5115 DFAVPLKDVTVPERRQARFECVLTREA--NVIWSKGPDI-IKSSDKFDIIADGKKHILVI 5171
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTVSLL------------VTEGQEKMDFKKMLKKRAP 175
DD Y A V+ + V EG+ ++ ++
Sbjct: 5172 NDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMH 5231
Query: 176 PAPKKKQKKVANEKEML-EILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAI 234
K K+ + +L K K + ++V ++ D + ++KE+ +++ +
Sbjct: 5232 VVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLD----DISQIKAQVKELSSTAQLKVL 5287
Query: 235 R----ILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
L DK + C + KD VK W K E + KY +K G
Sbjct: 5288 EADPYFTVKLHDKTAVEKDEITLKCEVS-KDVPVK--WFKDGEEI---VPSPKYSIKADG 5341
Query: 291 TKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIR 350
+ +L I ++ D G Y G + A +TV +K + V+V +TA FEI
Sbjct: 5342 LRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIE 5401
Query: 351 LSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKA 410
LS+ + + WK G+ L EI EDG H L + + +L +GE S +A N A
Sbjct: 5402 LSEPDVHGQWKLKGQPLTASPDCEII--EDGKKHILILHNCQLGMTGEVSFQAANAKSAA 5459
Query: 411 QLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEG 470
L + +P+ F++ L +V+V E+ A ECE++ + T RW K Q + ++ + +G
Sbjct: 5460 NLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDG 5519
Query: 471 KRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSP 530
+ ++I+ A D +Y A + +++ + +E + + DV A
Sbjct: 5520 TKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKFLTPLKDVTAKEKES 5573
Query: 531 AELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
A V L+ + + W K+ + + + + +G H + F + + + A G
Sbjct: 5574 AVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGM 5633
Query: 591 ESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTE 650
SEA + + + DP L + K ++ P V W+KDG E+
Sbjct: 5634 SSEAKLTVLEG---DPYFTGKLQDYTGVEKDEVILQCEISKADAP---VKWFKDGKEIKP 5687
Query: 651 EERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP---KPPQGR 707
+ ++ + +L + ++ D G + D G+ + L + DR P
Sbjct: 5688 SKNAVIKADGKKRMLILKKALKSDIG----QYTCDCGTDKTSGKLDIEDREIKLVRPLHS 5743
Query: 708 VEFL---------ELSGSCVHMKWK 723
VE + E+S +H WK
Sbjct: 5744 VEVMETETARFETEISEDDIHANWK 5768
Score = 143 bits (361), Expect = 1e-33
Identities = 192/826 (23%), Positives = 330/826 (39%), Gaps = 134/826 (16%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA-KIFYDSINKEHVL 125
P+ V P+PV EG+ A FR RV G +P ++W + K ++ YD I H L
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGI---HYL 1851
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPK------ 179
+ S D+ K A N + V L E Q++ DF+ +L++ P P+
Sbjct: 1852 DIVDCKSYDTGEVKVTAENPEGVIEHKVKL---EIQQREDFRSVLRRAPEPRPEFHVHEP 1908
Query: 180 -------------------------KKQKKVANEK---EMLEILSKVPKKDFEKVCMEYG 211
K+ +++ +EK E E+ SK ++ E
Sbjct: 1909 GKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAIT 1968
Query: 212 FTDFRGLLR--KLKEMKKKVEVEAIRILKPLEDKETK----------------------- 246
+ + + +E+ +K + E + K L ++E K
Sbjct: 1969 AVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPS 2028
Query: 247 VDTTVVFDCIME---------------LKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGT 291
++ +F+ I + P+ + W K ++I+ S Y
Sbjct: 2029 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNG--VKIERSDRIYWYWPEDN 2086
Query: 292 KYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPL-KFLGEMKPVKVTERQT-A 345
LVI +V D+ + G+ A L V + L F E++ V E+ T A
Sbjct: 2087 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2146
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSA---E 402
FE S+ W +G E+ DKY + D H L I SD+ ++S E
Sbjct: 2147 TFECETSEPFVKVKWYKDGMEVHEGDKYRM--HSDRKVHFLSILTIDTSDAEDYSCVLVE 2204
Query: 403 AGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGT 462
N+ A+L ++ ++FV L+++ V E LEC ++ +++ +W + L
Sbjct: 2205 DENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNG 2264
Query: 463 KYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSD 522
KY++ R L ++D D GEY+ V DG T T + ++ R + G+SD
Sbjct: 2265 KYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKT----TCKLKMKPRPIAILQGLSD 2318
Query: 523 VHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGK 582
G +L V ++ E VEGVW+KDG+E+ + IV H L+ M E G
Sbjct: 2319 QKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGN 2378
Query: 583 YTFR----AKGTESEASVFIAD--PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPL 636
Y+F T SV+ D P D +V+E K + VP +
Sbjct: 2379 YSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEG-------TKAVLECKVSVP----DV 2427
Query: 637 PKVTWYKDGMEVTEEERV-SMERGEDQALLTISNCVREDSG---LILLKLKNDHGSATAT 692
V WY + ++ ++RV ++ +G Q L+ I+ D G LI+ +++ + +
Sbjct: 2428 TSVKWYLNDEQIKPDDRVQAIVKGTKQRLV-INRTHASDEGPYKLIVGRVETNCNLSVEK 2486
Query: 693 LHL--SVLDRPKPPQGRVEF-LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
+ + + D V F +ELS S + + W KD +P +++ +E K +
Sbjct: 2487 IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNF-KDKEIKPSSKYKIEAHGKIYKLTV 2545
Query: 750 --KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEV 793
+ + +GK T ++ + GK L V +S PL + V
Sbjct: 2546 LNMMKDDEGKYTFYAGENMTSGK------LTVAGGAISKPLTDQTV 2585
Score = 143 bits (360), Expect = 1e-33
Identities = 157/639 (24%), Positives = 271/639 (42%), Gaps = 54/639 (8%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P GR E + ++ + V +KWK P +GG +T +IVE++ + W+K + T
Sbjct: 18230 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18289
Query: 761 FSTNKVEEGKAYQFRILAVNSEG-VSDPLETE-EVFAGNPIEPPGFASQPQVTDVTKEAV 818
F+ + + E + Y+FR++A N+ G S+P ++ + A + I+ P + P+ DV
Sbjct: 18290 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA 18349
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLED---TEYEFR 875
T+ G P+ + K G L + I+ T +++D T+
Sbjct: 18350 GETFVLEADIRGKPIPDVVWS--KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 18407
Query: 876 VIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPS 933
++ ++ G G S+P + V P P G L V+ + LAW P + G S
Sbjct: 18408 ILKLSNVG-GTKSIPITVKVLDRPGPPEG---PLKVTGVTAEKCYLAWNPPLQDGGANIS 18463
Query: 934 GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV 993
YI+E R W++ + + Y V L+ +Y FR+ AVN+ G+GEP+E
Sbjct: 18464 HYIIEKRETSRLSWTQVST-EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT 18522
Query: 994 RAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKG 1047
P PP+ P ++SA K MVV + G+ I +K D +
Sbjct: 18523 ACNPYKPPGPPSTP--EVSAITKDSMVVTWARPV----DDGGTEIEGYILEKRDKEGVRW 18576
Query: 1048 RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADF---PRPPTN 1101
+ K+ + + S +R+ +N G + + R D P PP+N
Sbjct: 18577 TKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSN 18636
Query: 1102 LRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAER--VFSNKYTVT 1157
++ + ++V+L W S + + G Y++ ++A+ W T + ++TVT
Sbjct: 18637 PKVTDTSRSSVSLAW--SKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVT 18694
Query: 1158 GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT 1217
L +Y FR+ A N G EP + ++ +++I+ +L +K V
Sbjct: 18695 KLKENTEYNFRICAINSEGVGEPATLPGS-VVAQERIEPPEIELDADLRK--------VV 18745
Query: 1218 PLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTL 1277
L+ LR + G P P V K + +T ++ TS LVI T
Sbjct: 18746 VLRASATLR-----LFVTIKGRPEPEVKWEKAEGILTDRAQI--EVTSSFTMLVIDNVTR 18798
Query: 1278 KDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
DSG Y++ +EN G + + V D V +I E
Sbjct: 18799 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIRE 18837
Score = 141 bits (356), Expect = 4e-33
Identities = 163/756 (21%), Positives = 295/756 (39%), Gaps = 74/756 (9%)
Query: 581 GKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVT 640
GKYT + S AS+ + P + +T K VP P
Sbjct: 19881 GKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVT-KESAVLSWDVPENDGGAPVKN 19939
Query: 641 WYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG---SATATLHLSV 697
++ + E +++ VS+ ++ ++N + +N+ G A + +
Sbjct: 19940 YHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI 19999
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
++P PP+ ++ +S V + W P+ +GG + ++VE G+K+W+K K
Sbjct: 20000 TEKPSPPE-KLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA--K 20056
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGFASQ--PQVTDVT 814
T+ + + E Y FR+ A N G+SDP E V +EPP + P T
Sbjct: 20057 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYV 20116
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE- 873
+ + + P G P+ + R VP+ T+ T + L + +
Sbjct: 20117 RAGSNLKVDIPIS--GKPLPKVTLSRDG------VPLKATMRFNTEITAENLTINLKESV 20168
Query: 874 ------FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA 927
+ + A N +G + + + VV P P G V +SD + S++L W P
Sbjct: 20169 TADAGRYEITAANSSGTTKAFI--NIVVLDRPGPPTGPVV---ISDITEESVTLKWEPPK 20223
Query: 928 E--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
G + YIL R T W++ + ++ T V L ++Y FRI+A N G+ +
Sbjct: 20224 YDGGSQVTNYILLKRETSTAVWTEVSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISD 20282
Query: 986 PVELDKGVRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDV 1036
++ +P PP+ P R + H V G + + +
Sbjct: 20283 HIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSI 20342
Query: 1037 IWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH---VRVA 1093
+WQK + + ++ + F + + +R+ +N G + V
Sbjct: 20343 LWQK------ANKLVIRT---THFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAI 20393
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSN 1152
D PP N+R+ + N+V+L+W YI+ +RD W A+ V
Sbjct: 20394 DACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTET 20453
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHA 1212
++ ++GL +Y FRV ARN +G I + S + P D
Sbjct: 20454 QFIISGLTQNSQYEFRVFARNAVGS----------------ISNPSEVVGPITCIDSYGG 20497
Query: 1213 PRFVTPLKPHTVLR---GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
P PL+ V++ G + G P PT+ YK D + N+ +T+ + +
Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20557
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
++I +SG Y + + N +G ++ + + DK
Sbjct: 20558 ILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20593
Score = 139 bits (349), Expect = 2e-32
Identities = 190/815 (23%), Positives = 305/815 (37%), Gaps = 84/815 (10%)
Query: 528 GSPAELCVVLNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
G P L ++ V W K G + G Q+ + L+ P+ + GKY+
Sbjct: 12249 GCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG-QVDLVDTMAFLVIPNSTRDDSGKYSLT 12307
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
E +VF+ P + L +T H + P +VT Y +
Sbjct: 12308 LVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSW--APPENDGGSQVTHYI--V 12363
Query: 647 EVTEEERVSMERGEDQALLT---ISNCVREDSGLILLKLKNDHGSATAT------LHLSV 697
E E +R + + T ++N V + + N++G T L
Sbjct: 12364 EKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12423
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKS--WIKIGEVD 755
L P PP+ ++E E++ + + W P +GG + +I R + + W + V
Sbjct: 12424 LSEPDPPR-KLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVV- 12481
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVT 814
K + ++EGK Y+FR+ A N+ GVS P E E V+ A + PP Q+T
Sbjct: 12482 -KDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQIT--I 12538
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEF 874
K + A P + + ++ + V+K D +D+ Y +
Sbjct: 12539 KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY-Y 12597
Query: 875 RVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPP 932
+ A N +G + + A P +PP +SD + SL+W P E G
Sbjct: 12598 SLTAENSSGTDTQKIKVVVMDAPGPPQPP-----FDISDIDADACSLSWHIPLEDGGSNI 12652
Query: 933 SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG 992
+ YI+E +W +C VG LI Q+Y FR+RA N G+ EP+ K
Sbjct: 12653 TNYIVEKCDVSRGDWVTALASVTKTSC-RVGKLIPGQEYIFRVRAENRFGISEPLTSPKM 12711
Query: 993 VRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT 1052
V P F + + K+ V + CI A+ PD G P G
Sbjct: 12712 VAQFP------FGVPSEPKNARVTKVNKD-CIFVAWDR---PD---SDGGSPIIGYLIER 12758
Query: 1053 KSKNH------SQFLINSTKRSDSGV-------YRILLQNEFGEA---RYDIHVRVADFP 1096
K +N + L+ ST+ +G+ +RI N+ G + + +V
Sbjct: 12759 KERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPV 12818
Query: 1097 RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWY---TAAERVFSNK 1153
PP + + +TV+L W Y + W TA ++ +
Sbjct: 12819 DPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEE 12878
Query: 1154 YTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ---DLSAKLKPYEKKDWR 1210
YT TGL +Y FR +AR + S P + D I + + DLS +K
Sbjct: 12879 YTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL----- 12933
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
TV G + + G P PTV+ K + +CTL
Sbjct: 12934 ------------TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTL 12981
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+ + KDSGDY++ EN G ++ L V DK
Sbjct: 12982 ELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 13016
Score = 137 bits (346), Expect = 5e-32
Identities = 219/998 (21%), Positives = 382/998 (38%), Gaps = 131/998 (13%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P K+ W K + I + K V + T LVI N +D+G YSL++ G+K +
Sbjct: 12262 PAPKVTWRK----VGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAV 12317
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITV 377
+ VLD P + ++K VT+ V + V + ++ + D K TV
Sbjct: 12318 FVNVRVLDTPGP-VSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTV 12376
Query: 378 SEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRAC 437
+ + + + + + F A N T P+ L + R
Sbjct: 12377 TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE---PDPPRKL 12433
Query: 438 LECELTSKDVTLRW---KKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQ 494
E+T TL W +DG + G S E + A+ E + + D V ++
Sbjct: 12434 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD-LSLVVTGLK 12492
Query: 495 DGDPTEYYSTA--------------IVTVEERL----------ATVKSGMS---DVHAAT 527
+G ++ A + +E+L T+K+G + H
Sbjct: 12493 EGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAH-VY 12551
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA 587
G P C W K E+ + + K + LI + + G Y+ A
Sbjct: 12552 GKPHPTC----------KWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTA 12601
Query: 588 K---GTESE---ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW 641
+ GT+++ V A P P + + A A ++ + HI + G + +
Sbjct: 12602 ENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL----SWHIPLEDGGSNI--TNY 12655
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG-SATATLHLSVLDR 700
+ +V+ + V+ + + + + ++ +N G S T V
Sbjct: 12656 IVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQF 12715
Query: 701 P-----KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVD 755
P +P RV +++ C+ + W P +GG P+ +++ER+ W+K +
Sbjct: 12716 PFGVPSEPKNARV--TKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTL 12773
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVT 814
+ T + + EG Y FRI A+N G S P + TE V A P++PPG +P+V DVT
Sbjct: 12774 VRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPG---KPEVIDVT 12830
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLLEDTEY 872
K V++ W P DGG+ ++GY VE K + WV N P I + T GL E +Y
Sbjct: 12831 KSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQY 12890
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSI------------- 919
+FR IA PS PS V PP + DL V+ S ++
Sbjct: 12891 QFRAIARTAVNISPPSEPSDPVTILAENVPPRI--DLSVAMKSLLTVKAGTNVCLDATVF 12948
Query: 920 -----SLAWR------EPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+++W+ +PAEG + R T E + T
Sbjct: 12949 GKPMPTVSWKKDGTLLKPAEGIK----MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 13004
Query: 969 QKYFFRIRAVNEAGVGEPVELDK--GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHA 1026
+ +++ +++ G V+++K RAM P D + + +++V + T+ A
Sbjct: 13005 KSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWA 13064
Query: 1027 AFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
S + P + + E + + + QF I + + G + + + Y
Sbjct: 13065 QVSATVP---------ITSCSVEKLIEGHEY-QFRICAENKYGVG-DPVFTEPAIAKNPY 13113
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA 1146
D R PP + ++ +T++W D Y++ KR+ W
Sbjct: 13114 DPPGRC----DPPVISNITKD---HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVN 13166
Query: 1147 ER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ + TGL G +Y FRV A N+ G +P D+
Sbjct: 13167 RKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDA 13204
Score = 137 bits (344), Expect = 9e-32
Identities = 160/649 (24%), Positives = 257/649 (39%), Gaps = 75/649 (11%)
Query: 690 TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
T L ++ +DRP P+ + + + V++KW+ P +GG P + VERR G W
Sbjct: 11718 TPILAINPIDRPGEPEN-LHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWE 11776
Query: 750 KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQ 809
++ + K T++ ++ E + Y+FR+ N G SD ++TEEV ++ P +
Sbjct: 11777 RVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLS 11836
Query: 810 VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLE 868
K TI A + P + + ++ V D +K ++
Sbjct: 11837 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11896
Query: 869 DTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE 928
++ V A N AG V ++V D PG V++L + D S+ ++ W P +
Sbjct: 11897 SDGGKYVVTATNTAGS---FVAYATVNVLDK---PGPVRNLKIVDVSSDRCTVCWDPPED 11950
Query: 929 --GDPPSGYILEMRAEDTKEWSKCTKIPIS-GTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
G YILE WS + ++ GT TV LIE +Y FR+RA N+ G G
Sbjct: 11951 DGGCEIQNYILEKCETKRMVWSTYSATVLTPGT--TVTRLIEGNEYIFRVRAENKIGTGP 12008
Query: 986 PVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPT 1045
P E + P A K+D R V + +PP + DG +
Sbjct: 12009 PTE------SKPVIAKTKYDKPGRPDPPEVTKVSKE---EMTVVWNPP-----EYDGGKS 12054
Query: 1046 KGRETITKSKNHSQFLINSTKRS--------------DSGVYRILLQNEFGEARYDIHVR 1091
+ K + HS + K + +R+ +NE G + R
Sbjct: 12055 ITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR 12114
Query: 1092 VA------DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKR----DAS 1138
+ P PPTN R+ + +++TL W DG A Y++ R DAS
Sbjct: 12115 PVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPV---YDGGAPIIGYVVEMRPKIADAS 12171
Query: 1139 TATWY---TAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ 1195
+ AA ++ ++TVT L ++Y FRV A+N++G P
Sbjct: 12172 PDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP--------------A 12217
Query: 1196 DLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA 1255
+L +KP E + + K V G + G P P VT K ++
Sbjct: 12218 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 12277
Query: 1256 NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
K + + LVIP T DSG YS+ + N G+ + V D
Sbjct: 12278 R-KGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLD 12325
Score = 135 bits (341), Expect = 2e-31
Identities = 152/639 (23%), Positives = 252/639 (39%), Gaps = 77/639 (12%)
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKA 771
+++ + + +KW PKDNG P+ + +E+R V W ++ + + + + EG
Sbjct: 8541 DVTSNSMLVKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 8599
Query: 772 YQFRILAVNSEG---VSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQD 828
Y FR+ A N+ G S P + + A +PI PPG P+VTD + + + W P +
Sbjct: 8600 YVFRVCAENAAGPGKFSPPSDPKT--AHDPISPPG-PPIPRVTDTSSTTIELEWEPPAFN 8656
Query: 829 GGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPS 888
GG ++GY V+++ G+N W + I+ + TV + E +Y+ RV AVN AG G P
Sbjct: 8657 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPG 8716
Query: 889 VPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWS 948
VA +P +PP + D+ V R PA ++ R TK W+
Sbjct: 8717 ETQPVTVA-EPQEPPAVELDVSVKGGIQIMAGKTLRIPA--------VVTGRPVPTKVWT 8767
Query: 949 KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP-------AA 1001
K G L + + + +E + + + D G + AA
Sbjct: 8768 K-----------EEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAA 8816
Query: 1002 PK---FDLSARLKSHMVVRAGTALCIHAAFSGSPPPD---------VIWQKDGVPTKGRE 1049
+ FD+ + V +C+ + S P D +I +KD R+
Sbjct: 8817 ARVEVFDVPGPVLDLKPVVTNRKMCL---LNWSDPEDDGGSEITGFIIERKDAKMHTWRQ 8873
Query: 1050 TITKSKNHSQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRL 1104
I ++ I +R++ +N+FG E + V P P L
Sbjct: 8874 PIETERSKCD--ITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTY 8931
Query: 1105 FEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGR 1163
E +T+TL W YII KR + +R+ + + V L +
Sbjct: 8932 TERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQ 8991
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHT 1223
Y FRV A NEIG+SEP S ++ +D + KL+ + D
Sbjct: 8992 MYEFRVKAVNEIGESEP--SLPLNVVIQDDEVPPTIKLRLSVRGD------------TIK 9037
Query: 1224 VLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS------KFWYNSTSGVCTLVIPTCTL 1277
V G+ + G P P + K + I + K + + L IP
Sbjct: 9038 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 9097
Query: 1278 KDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
+D G Y+V N LG + + VYD+ ++T+
Sbjct: 9098 EDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9136
Score = 130 bits (328), Expect = 6e-30
Identities = 143/631 (22%), Positives = 251/631 (39%), Gaps = 64/631 (10%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P G ++++++ + +KW P +GG + + +E+R G + W++ D
Sbjct: 21482 PVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQ-GNERWVRCNFTDVSECQ 21540
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE--VFAGNPIEPPGFASQPQVTD--VTKE 816
++ + G Y+FRI+A N+ G P + + PP P+ D + K
Sbjct: 21541 YTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKS 21600
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
++ A Q P + + + + + + + D + T V D + V
Sbjct: 21601 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTV 21659
Query: 877 IAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGD--PPSG 934
A N +G + + V +D P +V + ++ + ++L W P P +
Sbjct: 21660 EAKNASGSAKAEI---KVKVQDT--PGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITH 21714
Query: 935 YILEMRAEDTKEWS----KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELD 990
YI+E R W+ KC YT LI +Y FR+ AVN+ GVG P++ D
Sbjct: 21715 YIIEKRETSRLAWALIEDKC-----EAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSD 21769
Query: 991 KGVRAMP--PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKG 1047
V + P AP + + + + + GS I ++ + T+
Sbjct: 21770 PVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR---PESDGGSEIQQYILERREKKSTRW 21826
Query: 1048 RETITKSK-NHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV------ADFPRPPT 1100
+ I+K + ++F + + + ++ +N G R+ + P PPT
Sbjct: 21827 VKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPT 21886
Query: 1101 NLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTA-AERVFSNKYTVT 1157
+++ + TV+L W S V + G YII A W+ AE +YTVT
Sbjct: 21887 VVKVTDTSKTTVSLEW--SKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVT 21944
Query: 1158 GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ----DLSAKLKPYEKKDWRHAP 1213
L G +Y FRV A N G + + T + D++ D+ A K
Sbjct: 21945 DLQAGEEYKFRVSAINGAGKGDSCEVTGT-IKAVDRLTAPELDIDANFK----------- 21992
Query: 1214 RFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIP 1273
+ H V G + A+ G P PT K D N++ + ++T TL +
Sbjct: 21993 ------QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI--HTTDSFSTLTVE 22044
Query: 1274 TCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
C D+G Y++ VEN G + T+ V D
Sbjct: 22045 NCNRNDAGKYTLTVENNSGSKSITFTVKVLD 22075
Score = 130 bits (327), Expect = 8e-30
Identities = 192/809 (23%), Positives = 309/809 (38%), Gaps = 115/809 (14%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
W K EI D + + + L+ ++ GKYT + + S F+
Sbjct: 16604 WGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDT 16661
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW----YKDGMEVTEEERVSMERGED 661
PS L IT K +TW G ++ E
Sbjct: 16662 PSPPVNLKVTEIT---------------KDSVSITWEPPLLDGGSKIKNYIVEKREATRK 16706
Query: 662 QALLTISNCVRED----------SGLILLKLKNDHG---SATATLHLSVLDRPKPPQGRV 708
++NC + S + +N++G A + V + P+PP G++
Sbjct: 16707 SYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKI 16765
Query: 709 EFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEE 768
+++ + V + W P+ +GG + Q+IVE +A + W + V K + +
Sbjct: 16766 TVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARV--KSLQAVITNLTQ 16823
Query: 769 GKAYQFRILAVNSEGVSDP--LETEEVFAGNPIEP---PGFASQP-QVTDVTKEAV---- 818
G+ Y FR++AVN +G SDP L V IEP P F+S QV K V
Sbjct: 16824 GEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG 16883
Query: 819 ----TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEF 874
TITW T+DG P+ K+ + + V D + T ++ +D ++
Sbjct: 16884 RPKPTITW---TKDG-LPL--------KQTTRINVT---DSLDLTTLSIKETHKDDGGQY 16928
Query: 875 RVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPP 932
+ N G S+ ++ DP K P + D S SI+L+W P G
Sbjct: 16929 GITVANVVGQKTASIEIVTLDKPDPPKGP-----VKFDDVSAESITLSWNPPLYTGGCQI 16983
Query: 933 SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG 992
+ YI++ R T W ++ T V L +Y FRI A N G +E D
Sbjct: 16984 TNYIVQKRDTTTTVWD-VVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI 17042
Query: 993 VRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGV 1043
V P PP P ++ ++ H V G + I ++W
Sbjct: 17043 VAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW----- 17097
Query: 1044 PTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQN--EFGEARYDIHVRVADFP-RPPT 1100
TK +TI + +QF + + +R+ +N G+A + VA P PP
Sbjct: 17098 -TKVNKTII---HDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG 17153
Query: 1101 NLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAA-ERVFSNKYTVT 1157
N +TL W + V + G YI+ KRD W A+ V ++TV+
Sbjct: 17154 TPEPIMVKRNEITLQW--TKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVS 17211
Query: 1158 GLLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
GL ++Y FRV+A+N G S+P DS + KD+++ P D P+F
Sbjct: 17212 GLTEDQRYEFRVIAKNAAGAISKPSDSTGP-ITAKDEVE------LPRISMD----PKFR 17260
Query: 1217 TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
+ V G+ + G P PT+ +GD I +++ +T L++
Sbjct: 17261 DTI---VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAI 17317
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
D G Y + N G + V D+
Sbjct: 17318 RIDGGQYILRASNVAGSKSFPVNVKVLDR 17346
Score = 130 bits (326), Expect = 1e-29
Identities = 117/443 (26%), Positives = 200/443 (45%), Gaps = 28/443 (6%)
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K+ V I KPL D+ VF+C E+ +P+ K W++ + L + ++ +
Sbjct: 2568 KLTVAGGAISKPLTDQTVAESQEAVFEC--EVANPDSKGEWLRDGKHLPLTNNIRS---E 2622
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G K L+I+ ++D G Y+ V + SA+L V E +K +K + VTE Q AVF
Sbjct: 2623 SDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKV--EAVKIKKTLKNLTVTETQDAVF 2680
Query: 348 EIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+ L+ V W NG L+ ++KY I+V G ++L+IK+ + D + G L
Sbjct: 2681 TVELTHPNVKGVQWIKNGVVLESNEKYAISVK--GTIYSLRIKNCAIVDESVYGFRLGRL 2738
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
A+L ++ + K + K+V E + E ++ V ++W + K+ +
Sbjct: 2739 GASARLHVETV--KIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRL 2796
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
E K +L++++ SD GEYT V Q E + V E L K+ M ++
Sbjct: 2797 VSERKVHKLMLQNISPSDAGEYTAVVGQ----LECKAKLFV---ETLHITKT-MKNIEVP 2848
Query: 527 TGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
A ++ V +WLK+G EI +IV QG +H+LI + E +YTF
Sbjct: 2849 ETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV 2908
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
+ A++ + P + S+L+ + A K T + V + G W K+G+
Sbjct: 2909 CGNDQVSATLTVT--PIMITSMLKDINAEE---KDTITFEVTVNYEG---ISYKWLKNGV 2960
Query: 647 EVTEEERVSMERGEDQALLTISN 669
E+ ++ M + L I N
Sbjct: 2961 EIKSTDKCQMRTKKLTHSLNIRN 2983
Score = 130 bits (326), Expect = 1e-29
Identities = 162/646 (25%), Positives = 269/646 (41%), Gaps = 69/646 (10%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P GR E + ++ + V ++WK P +GG +T +IVE++ + + W+K + T+
Sbjct: 16066 PCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTH 16125
Query: 761 FSTNKVEEGKAYQFRILAVNSEGV-SDPLE-TEEVFAGNPIEPPGFASQPQVTD--VTKE 816
F + E Y+FR++A N+ GV S+P E T + A + ++PP + P+ D V
Sbjct: 16126 FEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHA 16185
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
+ +A P + +I ++ + + + + D + D+
Sbjct: 16186 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG---NY 16242
Query: 877 IAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSG 934
I K G+ SV + V P P G V +S + +LAW+ P + G
Sbjct: 16243 ILKAKNVAGERSVTVNVKVLDRPGPPEGPVV---ISGVTAEKCTLAWKPPLQDGGSDIIN 16299
Query: 935 YILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVR 994
YI+E R W+ + +C V L+E +Y FRI AVN+ GVGEP+E + V
Sbjct: 16300 YIVERRETSRLVWTVVDANVQTLSC-KVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVA 16358
Query: 995 AMP--PPAAPKF-DLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI 1051
P P APK +++ K M+V A+ GS + +K + +E I
Sbjct: 16359 KNPFVVPDAPKAPEVTTVTKDSMIVVWERP----ASDGGSEILGYVLEK-----RDKEGI 16409
Query: 1052 TKSKNHSQFLINSTKRSDSGV-------YRILLQNEFG------EARYDIHVRVADFPRP 1098
++ H + LI + +G+ +R+ +N G + Y P P
Sbjct: 16410 RWTRCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGP 16468
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDG--EAHYIIMKRDASTATWYTAAERVFSNKYT- 1155
P N ++ + ++V L+W S + + G YI+ K D S W NK
Sbjct: 16469 PNNPKVIDITRSSVFLSW--SKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNI 16526
Query: 1156 -VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ----DLSAKLKPYEKKDWR 1210
V LL +Y FR+ A N+ G E D +I +++++ DL +L+
Sbjct: 16527 EVEKLLEKHEYNFRICAINKAGVGEHADVPGP-IIVEEKLEAPDIDLDLELRKIINIRAG 16585
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
+ R P+K G P P V K D I + + TS +L
Sbjct: 16586 GSLRLFVPIK-----------------GRPTPEVKWGKVDGEIRDAAII--DVTSSFTSL 16626
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
V+ DSG Y++ +EN G + T+ V D V +TE
Sbjct: 16627 VLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTE 16672
Score = 129 bits (324), Expect = 2e-29
Identities = 180/796 (22%), Positives = 290/796 (36%), Gaps = 82/796 (10%)
Query: 543 EGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPP 602
E W ++ E TD +QI K +L + GKY + + + S F+
Sbjct: 17683 EITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17740
Query: 603 TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQ 662
P + LA + G K + D E T + ++ +
Sbjct: 17741 LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK-NYVIDKRESTRKAYANVSSKCSK 17799
Query: 663 ALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ--GRVEFLELSGSCVHM 720
+ N + +N+ G + + +PP G+V ++S + +
Sbjct: 17800 TSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASL 17859
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W+ P+ +GG V ++VE + G + W + E KV N + G+ YQFR+ A N
Sbjct: 17860 MWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAE--SKVCNAVVTGLSSGQEYQFRVKAYN 17917
Query: 781 SEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA------PVL 834
+G SDP G P+ QP ++ + +N + G PV+
Sbjct: 17918 EKGKSDPR-----VLGVPVIAKDLTIQP--------SLKLPFNTYSIQAGEDLKIEIPVI 17964
Query: 835 GYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY-----------EFRVIAVNKAG 883
G R + + WV + Q T+ V+ T ++ V A N AG
Sbjct: 17965 G-----RPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG 18019
Query: 884 PGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRA 941
++ S +V + P P G V+ + S + ++W PA G S YI+E R
Sbjct: 18020 TATENL--SVIVLEKPGPPVGPVR---FDEVSADFVVISWEPPAYTGGCQISNYIVEKRD 18074
Query: 942 EDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMP---- 997
T W + ++ T + L +Y FRI A N G P++ + P
Sbjct: 18075 TTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP 18133
Query: 998 -PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT 1052
PP P ++ ++ H V G I ++W K T ++T
Sbjct: 18134 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLN-KTPIQDTKF 18192
Query: 1053 KSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTV 1112
K+ + L K S + I ++ E D PP N V
Sbjct: 18193 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFV-----ARDPCDPPGRPEAIVITRNNV 18247
Query: 1113 TLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVA 1171
TL W YI+ K+D W A+ V ++TV+GL+ ++Y FRV+A
Sbjct: 18248 TLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIA 18307
Query: 1172 RNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDC 1230
RN G+ SEP DS + +D+I +A L P K V G+
Sbjct: 18308 RNAAGNFSEPSDSSGA-ITARDEIDAPNASLDPKYK-------------DVIVVHAGETF 18353
Query: 1231 TMTCAFLGNPRPTVTLYKGDVNITAN-SKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVEN 1289
+ G P P V K + ++ ST TLV+ C D G Y + + N
Sbjct: 18354 VLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSN 18413
Query: 1290 ELGKDRSSCTLTVYDK 1305
G T+ V D+
Sbjct: 18414 VGGTKSIPITVKVLDR 18429
Score = 123 bits (309), Expect = 1e-27
Identities = 159/650 (24%), Positives = 271/650 (41%), Gaps = 64/650 (9%)
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
L + L P P+ R+ + E + S + + WK P+ NGG P+ +I+E+R K + ++
Sbjct: 8915 LAVDPLGPPTSPE-RLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 8973
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVT- 811
+ T+F ++E + Y+FR+ AVN G S+P V + PP + V
Sbjct: 8974 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG 9033
Query: 812 DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP-----VNKDPIQG----TKCT 862
D K + P G P+ +E K + + P + K+ + T+ +
Sbjct: 9034 DTIKVKAGEPVHIPADVTGLPMPK--IEWSKNETVIEKPTDALQITKEEVSRSEAKTELS 9091
Query: 863 VDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ + + + + V A N+ G +V V D PP ++L V+D S L
Sbjct: 9092 IPKAVREDKGTYTVTASNRLGSVFRNV---HVEVYDRPSPP---RNLAVTDIKAESCYLT 9145
Query: 923 WREPAE--GDPPSGYILEMRAEDTK--EWSKCTKIPISGTCYTVGGLIERQKYFFRIRAV 978
W P + G + Y+++ R K EW + T + Y + LI +Y FR+RAV
Sbjct: 9146 WDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKR-YGIWKLIPNGQYEFRVRAV 9204
Query: 979 NEAGVGEPVELDKGVRAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
N+ G+ + + DK V P PP PK + AR K M+V L +G P
Sbjct: 9205 NKYGISDECKSDKVVIQDPYRLPGPPGKPK--VLARTKGSMLVSWTPPLD-----NGGSP 9257
Query: 1034 PDVIW---QKDGVP---TKGRETITK-SKNHSQFLINSTKRSDSGVYRILLQNEFG---- 1082
W +++G P R ITK +F + +R + N G
Sbjct: 9258 ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPP 9317
Query: 1083 EARYDIHVRVADF--PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDAS 1138
D V P PP+ + ++ ++++L W P ++ G YI+ ++
Sbjct: 9318 SEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWK--PPAKDGGSPIKGYIVEMQEEG 9375
Query: 1139 TATWYTAAER---VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ 1195
T W E + + + V L RKY FRV A NE G+SEP D+ T I IQ
Sbjct: 9376 TTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDT--TGEIPATDIQ 9433
Query: 1196 DLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTC-AFLGNPRPTVTLYKGDVNIT 1254
+ +D + + ++ V++G+ + F G + + D+
Sbjct: 9434 EEPEVFIDIGAQDCLVC-KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 9492
Query: 1255 ANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
A + NS+ ++IP C +G YS+ +N+ G+ ++C + V D
Sbjct: 9493 AQLETAENSS----VIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMD 9538
Score = 122 bits (307), Expect = 2e-27
Identities = 148/640 (23%), Positives = 248/640 (38%), Gaps = 83/640 (12%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
+RP PP G++ ++++ + V + W+ P+ +GG + +IVE + G W V KV
Sbjct: 15675 ERPLPP-GKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATV--KV 15731
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGF----------ASQ 807
T + + +G+ Y FR+ A N +G+SDP + V A + + PP F A +
Sbjct: 15732 TEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGE 15791
Query: 808 PQVTDVT---KEAVTITW---NAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
DV + +TW N P + E + S L +
Sbjct: 15792 DLKVDVPFIGRPTPAVTWHKDNVPLKQ----TTRVNAESTENNSLLTIK----------- 15836
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
D ED + + V N AG ++ + +V+ D PP + + + + SI+L
Sbjct: 15837 --DACREDVGH-YVVKLTNSAGE---AIETLNVIVLDKPGPP--TGPVKMDEVTADSITL 15888
Query: 922 AWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVN 979
+W P G + YI+E R T W + ++ T L +Y FRI A N
Sbjct: 15889 SWGPPKYDGGSSINNYIVEKRDTSTTTW-QIVSATVARTTIKACRLKTGCEYQFRIAAEN 15947
Query: 980 EAGVGEPVELDKGVRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSG 1030
G + + V P PP P LS+R ++ + + G + I
Sbjct: 15948 RYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLER 16007
Query: 1031 SPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYD--I 1088
++W K + I ++K F + +R+ +N G +
Sbjct: 16008 KERNSILWVK-----LNKTPIPQTK----FKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 16058
Query: 1089 HVRVADFP-RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA- 1146
VA P PP N+VTL W YI+ K++ W A+
Sbjct: 16059 ECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASF 16118
Query: 1147 ERVFSNKYTVTGLLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYE 1205
+ + VTGL+ +Y FRV+ARN G SEP +S + +D++ + P
Sbjct: 16119 TNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA-ITARDEVDPPRISMDPKY 16177
Query: 1206 KKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTS 1265
K V G+ + G P PT+ KGD ++ ++ ST
Sbjct: 16178 KDTI-------------VVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16224
Query: 1266 GVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+L + DSG+Y + +N G+ + + V D+
Sbjct: 16225 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDR 16264
Score = 122 bits (306), Expect = 2e-27
Identities = 200/934 (21%), Positives = 332/934 (35%), Gaps = 131/934 (14%)
Query: 441 ELTSKDVTLRWKK---DGQLLMHGTKYSMNHEGKRA-------------ELIIEDAQLSD 484
+ T K +L W K DG L + G G A + ++ D Q +
Sbjct: 14311 DTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKE 14370
Query: 485 GGEYTVVAMQD---GDPTEYYSTAIVTVE-----------ERLATVKSGMSD--VHAATG 528
+ + A+ D G+P IV E R V++G+S G
Sbjct: 14371 KYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKG 14430
Query: 529 SPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAK 588
PA E W KD + + ++ + + LI P GK+ +
Sbjct: 14431 RPAP----------EVTWTKDNINLKNRANIENTESFTL--LIIPECNRYDTGKFVMTIE 14478
Query: 589 GTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEV 648
+ S F+ P + L IT K T H +P G +
Sbjct: 14479 NPAGKKSGFVNVRVLDTPGPVLNLRPTDIT-KDSVTLHWDLPL----------IDGGSRI 14527
Query: 649 TE---EERVSMERGEDQALLTISNCVREDSGL-------ILLKLKNDHG---SATATLHL 695
T E+R + + A C + +GL + +N++G T +
Sbjct: 14528 TNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPV 14587
Query: 696 SVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVD 755
+ P PP + ++++ S V + W PK +GG +T +++E + G W I V
Sbjct: 14588 KASEAPSPPDS-LNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVK 14646
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQP--QVTDV 813
G + EG+ Y F+++AVNS G S P E+ V P + Q +
Sbjct: 14647 G--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14704
Query: 814 TKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCT----VDGLLED 869
K I P P + + KKG + + + T + ++ +
Sbjct: 14705 AKAGDNIKVEIPVLGRPKPTVTW-----KKGDQILKQTQRVNFETTATSTILNINECVRS 14759
Query: 870 TEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE- 928
+ + A N G + ++ D PP + + S+ ++ +W P
Sbjct: 14760 DSGPYPLTARNIVGEVGDVI---TIQVHDIPGPP--TGPIKFDEVSSDFVTFSWDPPEND 14814
Query: 929 -GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPV 987
G P S Y++EMR D+ W + I T Y L +Y FR++A N GVG +
Sbjct: 14815 GGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRYGVGPGI 14873
Query: 988 ELDKGVRAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG 1042
V P PP P+ ++A K M + H S P + + +
Sbjct: 14874 TSACIVANYPFKVPGPPGTPQ--VTAVTKDSMTISW------HEPLSDGGSPILGYHVER 14925
Query: 1043 VPTKGRETITKSKNHSQFLINSTKRSDSGV---YRILLQNEFGEARYD------IHVRVA 1093
G T SK I + G+ +R++ +N G+++ + +
Sbjct: 14926 KERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPI 14985
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSN 1152
D P P L + +TVTL W YI+ KRD W A + N
Sbjct: 14986 DPPGKPVPLNITR---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILEN 15042
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHA 1212
++TV+GL Y FRV+A+N G P + +D ++ + K+K K
Sbjct: 15043 EFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVE--APKIKVDVK------ 15094
Query: 1213 PRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLV 1271
K +L+ G+ + G P PT+ K + +K LV
Sbjct: 15095 ------FKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLV 15148
Query: 1272 IPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
T +DSG Y++ N G + + V D+
Sbjct: 15149 NKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDR 15182
Score = 121 bits (303), Expect = 5e-27
Identities = 146/660 (22%), Positives = 265/660 (40%), Gaps = 56/660 (8%)
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLE 128
F ++ Q V A E D + W ++ G+ + E K S K H L +
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKD-GMEVHEGDKYRMHSDRKVHFLSIL 2188
Query: 129 PLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANE 188
+ + D+++Y C+ D + + T + L+ EG ++F K L+ P + +
Sbjct: 2189 TIDTSDAEDYSCVLVED--ENVKTTAKLIVEG-AVVEFVKELQDIEVPESYSGELECIVS 2245
Query: 189 KEMLEILSKVPKKDFE-KVCMEYGFTDFRG--------------------LLRKLKEMKK 227
E +E K D E K +Y T RG + K K
Sbjct: 2246 PENIE--GKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K++ I IL+ L D++ V + + L+ +V+ +W+K + ++ + K
Sbjct: 2304 KMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE--SVEGVWMKDGQEVQPSDRVHIVIDK 2361
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
Q +ML+I ++ DAG YS ++ +S V + + +K V V E AV
Sbjct: 2362 Q---SHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVL 2418
Query: 348 EIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
E ++S + V W N +++K DD+ + V G L I SD G + G +
Sbjct: 2419 ECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK--GTKQRLVINRTHASDEGPYKLIVGRV 2476
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
L++++ IK + L+++ E E EL+ + + W + + +KY +
Sbjct: 2477 ETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKI 2534
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
GK +L + + D G+YT A E ++ +TV + ++D A
Sbjct: 2535 EAHGKIYKLTVLNMMKDDEGKYTFYA------GENMTSGKLTVAG--GAISKPLTDQTVA 2586
Query: 527 TGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A C V N + +G WL+DGK + ++ G +LI + + G+YT+
Sbjct: 2587 ESQEAVFECEVANPDS-KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTY 2645
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+ +++ A + + +V +TV A V + V W K+G
Sbjct: 2646 KVATSKTSAKLKV-------EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNG 2698
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
+ + E+ ++ L I NC D + +L A+A LH+ + K P+
Sbjct: 2699 VVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL--GRLGASARLHVETVKIIKKPK 2756
Score = 121 bits (303), Expect = 5e-27
Identities = 150/654 (22%), Positives = 261/654 (39%), Gaps = 83/654 (12%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P G+ E ++++ S V + W PK +GG + + VE + W++ ++
Sbjct: 12817 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12876
Query: 761 --FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE---VFAGNPIEPPGFASQPQVTDVTK 815
++ +EE YQFR +A + +S P E + + A N + + K
Sbjct: 12877 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVK 12936
Query: 816 EAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN--KDPIQGTKCTVD--GLLEDTE 871
+ +A P + + KK L P K +Q CT++ +
Sbjct: 12937 AGTNVCLDATVFGKPMPTVSW-----KKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12991
Query: 872 YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--G 929
++ + A N +G S+ + + PG + ++ + L+W P E G
Sbjct: 12992 GDYTITAENSSGS------KSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGG 13045
Query: 930 DPPSGYILEMRAEDTKEWSKCTK-IPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE 988
+ YI++ R W++ + +PI T +V LIE +Y FRI A N+ GVG+PV
Sbjct: 13046 SEITNYIVDKRETSRPNWAQVSATVPI--TSCSVEKLIEGHEYQFRICAENKYGVGDPVF 13103
Query: 989 LDKGVRAMPPPAAPKFD---LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPT 1045
+ + P + D +S K HM V S PP D G P
Sbjct: 13104 TEPAIAKNPYDPPGRCDPPVISNITKDHMTV------------SWKPPAD----DGGSPI 13147
Query: 1046 KG-----RET--ITKSKNHSQFLINSTKRSDSGV-------YRILLQNEFG-----EARY 1086
G RET + +K + + +I T ++ +G+ +R+ N+ G +A
Sbjct: 13148 TGYLLEKRETQAVNWTKVNRKPIIERTLKA-TGLQEGTEYEFRVTAINKAGPGKPSDASK 13206
Query: 1087 DIHVRVADFPR-PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTA 1145
+ R +P PP ++++ ++V+L+W Y++ + A + W
Sbjct: 13207 AAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRC 13266
Query: 1146 --AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203
+ + ++ VTGL+ +Y FRV A N+IG S+P D D K +D+ + P
Sbjct: 13267 NLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPD-----KHYPKDIL--IPP 13319
Query: 1204 YEKKDWRHAPRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
+ D L+ +LR G + G P P +T K +VN+
Sbjct: 13320 EGELD--------ADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK 13371
Query: 1263 STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
ST L D+G Y + +EN GK + + V D V ++ E
Sbjct: 13372 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKE 13425
Score = 121 bits (303), Expect = 5e-27
Identities = 140/627 (22%), Positives = 244/627 (38%), Gaps = 83/627 (13%)
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
V + W P +GG +T+++VER+ G+++W G K ++++E +FR+
Sbjct: 21107 VILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGI--SKTCEIEVSQLKEQSVLEFRVF 21164
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTIT------WNAPTQDGGA 831
A N +G+SDP+ + I P + ++D+ VT+ P +
Sbjct: 21165 AKNEKGLSDPVTIGPITVKELIITP----EVDLSDIPGAQVTVRIGHNVHLELPYKGKPK 21220
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
P + ++ + + +V +K + T ++ ++ ++ VI N + +VP
Sbjct: 21221 PSISWLKDGLPLKESEFVRFSKTENKIT-LSIKNAKKEHGGKYTVILDNAVC--RIAVPI 21277
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSK 949
+ + P KP G ++ + S+ L+W P + G + Y +E R W K
Sbjct: 21278 TVITLGPPSKPKGPIR---FDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW-K 21333
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEP-----VELDKGVRAMPPPAAPKF 1004
++ T + V L++ +Y FR+RA N GV +P + R PP P
Sbjct: 21334 MVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVI 21393
Query: 1005 DLSARLKSHMVVRAGTALCIHA-AFSGSPPP-----------DVIWQKDGV-PTKGRETI 1051
+ V G +L A + G ++WQK P GRE
Sbjct: 21394 --------YNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGRE-- 21443
Query: 1052 TKSKNHSQFLINSTKRSDSGVYRILLQNEFG------EARYDIHVRVADFPRPPTNLRLF 1105
+ +R+ +N G +++ + V D P P + +
Sbjct: 21444 --------YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVT 21495
Query: 1106 EEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGR 1163
E T+TL WN P +++ G Y I KR + V +YTVTGL PG
Sbjct: 21496 RE---TITLKWN--PPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGD 21550
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHT 1223
+Y FR++ARN +G P ++ +D+ + P + P + L
Sbjct: 21551 RYEFRIIARNAVGTISPPSQSSGIIMTRDE------NVPPIVE----FGPEYFDGL---I 21597
Query: 1224 VLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDY 1283
+ G+ + G P P VT +K V I G +L + T G Y
Sbjct: 21598 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21657
Query: 1284 SVLVENELGKDRSSCTLTVYDKDDKSV 1310
+V +N G ++ + V D K V
Sbjct: 21658 TVEAKNASGSAKAEIKVKVQDTPGKVV 21684
Score = 120 bits (302), Expect = 7e-27
Identities = 163/681 (23%), Positives = 272/681 (39%), Gaps = 74/681 (10%)
Query: 361 KFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIK 420
+ N EL R + + +G + +IK A + GE A +++ K L + +
Sbjct: 11480 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 11539
Query: 421 FVS-NLKNVRVKERSRACLECE-LTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIE 478
++ VRV + R + D+T W K+G++L+ + + + R EL I+
Sbjct: 11540 VTCRDVITVRVGQTIRILARVKGRPEPDIT--WTKEGKVLVREKRVDLIQDLPRVELQIK 11597
Query: 479 DAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLN 538
+A +D G+Y + A + +AIV V +R G T E C +
Sbjct: 11598 EAVRADHGKYIISAKNSSGHAQ--GSAIVNVLDR-----PGPCQNLKVTNVTKENCTISW 11650
Query: 539 DEKVEGVWLKDGKEITDL---------PGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKG 589
+ ++ G EIT+ G IV +LI ++ +E Y FR
Sbjct: 11651 ENPLD----NGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNE--YYFRV-C 11703
Query: 590 TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYK---DGM 646
E++ V PTI+ LA + I + G ++ + +GK + W + DG
Sbjct: 11704 AENKVGV----GPTIETKT-PILAINPID-RPGEPENLHIADKGKTFVYLKWRRPDYDGG 11757
Query: 647 EVTEEERVSME-RGED-----------QALLTISNCVREDSGLILLKLKNDHGSATATLH 694
V +G D + + CV ++ KN+ G +
Sbjct: 11758 SPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKT 11817
Query: 695 LSVL---DRPKPPQGRVEFLELSGSCV-----HMKWKAPKDNGGRPVTQFIVERRA--VG 744
V+ D KP V L+LSG ++ +A P + ++ A +
Sbjct: 11818 EEVVVKEDLQKP----VLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11873
Query: 745 KKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGF 804
+ +KI + + FS K + ++ + A N+ G T N ++ PG
Sbjct: 11874 RSPRVKI-DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATV-----NVLDKPGP 11927
Query: 805 ASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI-QGTKCTV 863
++ DV+ + T+ W+ P DGG + YI+E+ + +W + + GT TV
Sbjct: 11928 VRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGT--TV 11985
Query: 864 DGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAW 923
L+E EY FRV A NK G G P+ S V+AK PG V+ S +++ W
Sbjct: 11986 TRLIEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVW 12044
Query: 924 REPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEA 981
P G +GY LE + + + W K I V L+ +Y FR++A NE
Sbjct: 12045 NPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEI 12104
Query: 982 GVGEPVELDKGVRAMPPPAAP 1002
G+GEP + V A P P
Sbjct: 12105 GIGEPSLPSRPVVAKDPIEPP 12125
Score = 117 bits (294), Expect = 6e-26
Identities = 148/628 (23%), Positives = 233/628 (37%), Gaps = 87/628 (13%)
Query: 713 LSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAY 772
+S S + WK P +GG + ++V+ K W ++ + +S + EGK Y
Sbjct: 13523 VSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRV--MKSLSLQYSAKDLTEGKEY 13579
Query: 773 QFRILAVNSEGVSDPLETEEVFAGNPIEPP-GFASQPQVTDVTKEAVTITWNAPTQDGGA 831
FR+ A N G P E V + + P P + + KE P + A
Sbjct: 13580 TFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPA 13639
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
P + + ++ V V + T D D ++ + N AG + ++ S
Sbjct: 13640 PSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAG-KYTITLKNVAGTKEGTI-S 13697
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSK 949
VV K P P G ++ + + +++L W P + G + YILE R +W
Sbjct: 13698 IKVVGK-PGIPTGPIK---FDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13753
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSAR 1009
C + T + V L E +Y FR+ A N+ GVGE G+++ P A FD+
Sbjct: 13754 CASA-VQKTTFRVTRLHEGMEYTFRVSAENKYGVGE------GLKSEPIVARHPFDVP-- 13804
Query: 1010 LKSHMVVRAGTALCIHAAFSGSPPPDVI----------W----QKDGVPTKGRETITKSK 1055
PPP+++ W + G P G K +
Sbjct: 13805 -------------------DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKER 13845
Query: 1056 NH-------------SQFLINSTKRSDSGVYRILLQNEFGEARYDIH---VRVADFPRPP 1099
N F + +R++ N G + + V D PP
Sbjct: 13846 NSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13905
Query: 1100 TNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAE-RVFSNKYTVTG 1158
+ N+VTL W YI+ KRD + +W A V +TVT
Sbjct: 13906 GKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTD 13965
Query: 1159 LLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT 1217
L+ G KY FR+ A+N G S P +S +T +I KD+ + + L P K
Sbjct: 13966 LVEGGKYEFRIRAKNTAGAISAPSESTET-IICKDEYEAPTIVLDPTIKDGL-------- 14016
Query: 1218 PLKPHTVLRGQDCTMTC-AFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
T+ G + + LG P P + K +I + ST L I T
Sbjct: 14017 -----TIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 14071
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYD 1304
KD+G+Y++ N G +TV D
Sbjct: 14072 RKDAGEYTITATNPFGTKVEHVKVTVLD 14099
Score = 109 bits (273), Expect = 2e-23
Identities = 145/639 (22%), Positives = 241/639 (37%), Gaps = 71/639 (11%)
Query: 695 LSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEV 754
++V +RP+ +E E++ + V + W PK +GG + +++E R +G + + K+
Sbjct: 10342 ITVPERPED----LEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTND 10397
Query: 755 DGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVT 814
+ ++ ++EG Y++R+ AVN G P F PI + P +
Sbjct: 10398 NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPS-----FCTKPITCKDELAPPTLHLDF 10452
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE- 873
++ +TI + G A L + K W D ++ + + E
Sbjct: 10453 RDKLTI------RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEK 10506
Query: 874 ----------FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAW 923
+ V+ N G + + V D PP V + + + + ++W
Sbjct: 10507 IKAKRSDSGKYCVVVENSTGSRKGFCQVNVV---DRPGPP--VGPVSFDEVTKDYMVISW 10561
Query: 924 REPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEA 981
+ P + G + YI+E + W T TC V L+E + Y FRI A N
Sbjct: 10562 KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTC-KVSKLLEGKDYIFRIHAENLY 10620
Query: 982 GVGEPVELD--KGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQ 1039
G+ +P+ D K P AP + + + G P + I +
Sbjct: 10621 GISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNK----PHDGGKPITNYILE 10676
Query: 1040 KDGVPTKGRETITKSKNH--SQFLINSTKRSDSGVYRILLQNEFG------EARYDIHVR 1091
K +K +TK H ++F + +R+ +NE G ++
Sbjct: 10677 KRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKD 10736
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTA---A 1146
P PP N + N+V LTW P + G YI+ + W A
Sbjct: 10737 PIAKPSPPVNPEAIDTTCNSVDLTWQ--PPRHDGGSKILGYIVEYQKVGDEEWRRANHTP 10794
Query: 1147 ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEK 1206
E KY VTGL G+ Y FRV+A N G+S+P + L+ KD+++ L
Sbjct: 10795 ESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLV-KDRLEPPELILD---- 10849
Query: 1207 KDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG 1266
+ + G ++ G P P VT K D + A +K + T
Sbjct: 10850 ---------ANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD--APTKARIDVTPV 10898
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
L I +D G YS+ VEN G S + V DK
Sbjct: 10899 GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 10937
Score = 107 bits (268), Expect = 6e-23
Identities = 144/617 (23%), Positives = 249/617 (40%), Gaps = 55/617 (8%)
Query: 217 GLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLR 276
G K K VE +R +K LE++ T V ++ K+ +V +W K +
Sbjct: 4823 GNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDV--VWRKDGKI-- 4878
Query: 277 IQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV---GDKRMSAELTVLDEPLKFLGE 333
+ G+ +G L I++ + DAG Y+++V + S+ + V++ +L
Sbjct: 4879 VVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWL-- 4936
Query: 334 MKPVK---VTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKD 390
+KP++ V + TA+F ++K PN W E+ + + + DG LKIK+
Sbjct: 4937 VKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKN 4996
Query: 391 ARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLR 450
A D E++ E A+LT+ ++ + +++V + E+ A + E++ D+ +
Sbjct: 4997 AMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQ 5056
Query: 451 WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVE 510
WK G+LL + EG + L + +L GE A+ +TAI+TV+
Sbjct: 5057 WKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQAL------NAITTAILTVK 5110
Query: 511 ERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHK 569
E + DV A CV+ + V +W K I I+ G H
Sbjct: 5111 EIELDFAVPLKDVTVPERRQARFECVLTREANV--IWSKGPDIIKSSDKFDIIADGKKHI 5168
Query: 570 LIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKV 629
L+ + EG YT +G ++ A +F+ S LE TVK G TA
Sbjct: 5169 LVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQ-----TVKEGETATFVC 5223
Query: 630 PFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA 689
+ + V W+K+ ++ V + L + +D I ++K
Sbjct: 5224 ELSHEKM-HVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVK----EL 5278
Query: 690 TATLHLSVLDRPK------PPQGRVEFLELSGSC-----VHMKWKAPKDNGGRPVTQFIV 738
++T L VL+ + VE E++ C V +KW +G V
Sbjct: 5279 SSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKW---FKDGEEIVPSPKY 5335
Query: 739 ERRAVGKKSWIKIGEVDGK-----VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEV 793
+A G + +KI + D K V + T+K + + R++ V PL EV
Sbjct: 5336 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEK-----PLYGVEV 5390
Query: 794 FAGNPIEPPGFASQPQV 810
F G S+P V
Sbjct: 5391 FVGETAHFEIELSEPDV 5407
Score = 107 bits (266), Expect = 1e-22
Identities = 168/748 (22%), Positives = 293/748 (39%), Gaps = 96/748 (12%)
Query: 232 EAIRILKPLEDKETKVDTTVVFDC-IMELKDPNVKMIWIK-GTEPLRIQYSLGKYDVKQM 289
EA I K ++D TK+ C I+ P++K W + G E ++ + KY +
Sbjct: 24159 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSR----KYKMSSD 24212
Query: 290 GTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
G + L + D G+Y+ VG+ S++L + P G P+K
Sbjct: 24213 GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGY--PLKEKYYGAV 24270
Query: 346 VFEIRL-----SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFS 400
+RL + P W F+G++L ++ + + + TH + R + +G++
Sbjct: 24271 GSTLRLHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYK 24329
Query: 401 AEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMH 460
+ N+ +D +++ K +E L + V + WK
Sbjct: 24330 VQLSNVFGTVDAILD-------VEIQDKPDKPTGPIVIEALLKNSAV-ISWKPPAD---D 24378
Query: 461 GTKYSMNH--------EGKRAELIIEDAQLS---------DGGEYTVVAMQD----GDPT 499
G + N+ EG +L+ ++ + G Y V+ Q+ DP
Sbjct: 24379 GGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPL 24438
Query: 500 EYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVL-------NDEKVEGVWLKDGKE 552
E S I+ + K G T + CVV K+ +L+ +E
Sbjct: 24439 EVSSVVII----KSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEK-RE 24493
Query: 553 ITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAK----GTESEASVFI------ADPP 602
+ + + + + +F +Y FR K G ESE S +D P
Sbjct: 24494 KKQNKWISVTTE-EIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVP 24552
Query: 603 TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEE---RVSMERG 659
P E L + V+ A + G P P V WY+ G E+ + R+ +G
Sbjct: 24553 IQAPHFKEEL--RNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKG 24610
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV-----LDRPKPPQGRVEFLELS 714
L+ I++ +D+ + ++ N GS + T L V + PK +G L
Sbjct: 24611 GYHQLI-IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALR 24669
Query: 715 GSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQF 774
G V +K P PV + + + ++ + N VE A +
Sbjct: 24670 GEVVSIK--IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFY 24727
Query: 775 RILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVL 834
+ A N G+ +T E+ + +PP +V+DV++++V +TW P DGG+ +
Sbjct: 24728 VVCAKNRFGIDQ--KTVELDVADVPDPPRGV---KVSDVSRDSVNLTWTEPASDGGSKIT 24782
Query: 835 GYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSV 894
YIVE+ + W+ V + + T+ TV L T Y+FRVIA NK G +PS PS
Sbjct: 24783 NYIVEKCATTAERWLRVGQ--ARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPT 24840
Query: 895 VAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ K+ K + D V ++ S++ A
Sbjct: 24841 ITKED-KTRAMNYDEEVDETREVSMTKA 24867
Score = 98.2 bits (243), Expect = 5e-20
Identities = 145/714 (20%), Positives = 274/714 (38%), Gaps = 108/714 (15%)
Query: 3 TIHSRQMLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPA 62
T+ + L VS EF TT V T K EE +S +V + +T P
Sbjct: 977 TVSTSCYLAVQVSEEFEKETTAV-----TEKFTTEEKRFVESRDVVMTDTSLTEEQAGPG 1031
Query: 63 GDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA--KIFYDSIN 120
+ P F+ KP EG VF +V GN KPH+ WK+ SG+P+ K+ Y+
Sbjct: 1032 EPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK-SGVPLTTGYRYKVSYNKQT 1090
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK 180
E L + +DD+ Y + N H + + SLL E+ D++ ++K + +
Sbjct: 1091 GECKLVISMTFADDAGEYTIVVRNKHGETSASASLL-----EEADYELLMKSQQEMLYQT 1145
Query: 181 KQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPL 240
+ E ++ E ++EK EY ++ ++KK+ + + + +
Sbjct: 1146 QVTAFVQEPKVGETAPGFVYSEYEK---EYE--------KEQALIRKKMAKDTVVVRTYV 1194
Query: 241 EDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNV 300
ED+E + + ++ +K I+Y + K ++++
Sbjct: 1195 EDQEFHISS---------FEERLIK----------EIEYRIIKTTLEEL----------- 1224
Query: 301 NMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKE-PNFV 359
+ + G ++V A + D +K ++ E F ++S P
Sbjct: 1225 -LEEDGEEKMAVDISESEAVESGFDS------RIKNYRILEGMGVTFHCKMSGYPLPKIA 1277
Query: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQLTID 415
W +GK +K ++Y++ +DG +L+I D G ++A A GN + +L ++
Sbjct: 1278 WYKDGKRIKHGERYQMDFLQDGRA-SLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Query: 416 -RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAE 474
P+ + + + R R+ ++ + + + M + S
Sbjct: 1337 PAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMS--------- 1387
Query: 475 LIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH--AATGSPAE 532
A++S G +++ D ++ ERL + V G A
Sbjct: 1388 ----PARMSPGRR-----LEETDESQL---------ERLYKPVFVLKPVSFKCLEGQTAR 1429
Query: 533 LCV-VLNDEKVEGVWLKDGKEIT-DLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
+ V+ E W DG++I D ++K+ LI P G++T A+
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489
Query: 591 ESEASVFI-----ADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+S+ + A + P +E L + +K G +KV G P P + W K+
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKN--VNIKEGSRLEMKVRATGNPNPDIVWLKNS 1547
Query: 646 MEVTEEE--RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
+ + ++ +E + +A L I + V +DS N G T ++V
Sbjct: 1548 DIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1601
Score = 95.9 bits (237), Expect = 2e-19
Identities = 152/639 (23%), Positives = 238/639 (37%), Gaps = 111/639 (17%)
Query: 430 VKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
VK + CL+ + K + T+ WKKDG LL M + L + D G+Y
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12994
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCV-VLNDEKVEGVW- 546
T+ TA + + AT+K + D G PA + + + ++ W
Sbjct: 12995 TI-------------TAENSSGSKSATIKLKVLD---KPGPPASVKINKMYSDRAMLSWE 13038
Query: 547 --LKDG----------KEITDLPGMQIVKQG------AVHKLIFPSMGPEHEGKYTFRAK 588
L+DG K T P V +V KLI HE ++ A+
Sbjct: 13039 PPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLI-----EGHEYQFRICAE 13093
Query: 589 G---------TESEASVFIADPP-TIDPSVLEALAAHAITVKVGHTAHIK-VPFRGKPLP 637
TE + DPP DP V+ + +TV A P G L
Sbjct: 13094 NKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLE 13153
Query: 638 K-----VTWYKDGMEVTEEERVS----MERGEDQALLTISNCVREDSGLILLKLKNDHGS 688
K V W K + E + E E + +T N K G
Sbjct: 13154 KRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAIN-------------KAGPGK 13200
Query: 689 ATATLHLSVLDRPKPPQGRVEF---LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGK 745
+ + P+ P G F + + S V + W P +GG P+ ++VE +
Sbjct: 13201 PSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS 13260
Query: 746 KSWIKIGEVDG-KVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLET-EEVFAGNPIEPPG 803
+W++ + T F + E YQFR+ AVN G SDP + ++ + + + PP
Sbjct: 13261 DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPE 13320
Query: 804 --FASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
+ + T + + VT+ P + P + + K NL + D
Sbjct: 13321 GELDADLRKTLILRAGVTMRLYVPVKGRPPPKITW----SKPNVNLRDRIGLD------- 13369
Query: 862 TVDGLLEDTEYE--FRVIAVNKAGPGQPSVPSSSVVAKDP-------VKPPGLVQDLHVS 912
++ T+++ R VNK G+ + + K + PG ++ V
Sbjct: 13370 -----IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVK 13424
Query: 913 DSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQK 970
+ S S + W P G P Y+++ R + K WS T S T + V L E +
Sbjct: 13425 EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTT-ECSKTSFRVANLEEGKS 13483
Query: 971 YFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSAR 1009
YFFR+ A NE G+G+P E V+A P P DL R
Sbjct: 13484 YFFRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVR 13521
Score = 92.8 bits (229), Expect = 2e-18
Identities = 110/495 (22%), Positives = 193/495 (38%), Gaps = 34/495 (6%)
Query: 232 EAIRILKPLEDKETKV-DTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
+ I + L+D K DT F+C E +P VK+ W K + + KY +
Sbjct: 2126 QLITFTQELQDVVAKEKDTMATFEC--ETSEPFVKVKWYKDGMEV---HEGDKYRMHSDR 2180
Query: 291 TKYMLVISNVNMNDAGIYS-LSVGDKRM--SAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+ L I ++ +DA YS + V D+ + +A+L V ++F+ E++ ++V E +
Sbjct: 2181 KVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGEL 2240
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E +S + W N ELK + KY IT S G L +KD D GE+S
Sbjct: 2241 ECIVSPENIEGKWYHNDVELKSNGKYTIT-SRRG-RQNLTVKDVTKEDQGEYSFVIDGKK 2298
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
+L + PI + L + +V E LE +++ + V W KDGQ + + +
Sbjct: 2299 TTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIV 2358
Query: 468 HEGKRAELIIEDAQLSDGGEYT----VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
+ + L+IED D G Y+ + + YS ++T + DV
Sbjct: 2359 IDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVIT----------PLKDV 2408
Query: 524 HAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGK 582
+ G+ A L C V + W + ++I +Q + +G +L+ EG
Sbjct: 2409 NVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGP 2468
Query: 583 YTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWY 642
Y E+ ++ + ++ L T +++ G V W
Sbjct: 2469 YKLIVGRVETNCNLSVE-----KIKIIRGLRDLTCTETQNVVFEVELSHSG---IDVLWN 2520
Query: 643 KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPK 702
E+ + +E LT+ N +++D G + S T+ + +P
Sbjct: 2521 FKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAISKPL 2580
Query: 703 PPQGRVEFLELSGSC 717
Q E E C
Sbjct: 2581 TDQTVAESQEAVFEC 2595
Score = 88.2 bits (217), Expect = 5e-17
Identities = 139/589 (23%), Positives = 233/589 (39%), Gaps = 79/589 (13%)
Query: 65 SVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV 124
+ P K +P+ G A F +Q W + +G I ES K S +++
Sbjct: 4460 AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFK-AGREIYESDKCSIRS--SKYI 4516
Query: 125 LKLEPLTSD--DSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPA----- 177
LE L + D Y C ASN++ T +L VT + +K+L +R P
Sbjct: 4517 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV 4576
Query: 178 --------PKKKQKKVANEKEMLEILSK--VPKKDFEKVCMEYGFTDFRGLLRKLKEMKK 227
P++++ KV E + LE + K VP+ K E RK+ E K
Sbjct: 4577 LKSVLRKRPEEEEPKV--EPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK 4634
Query: 228 KVEVEA----------------IRILKP--LEDKETKVDTTVVFDCI---MELKDPNVKM 266
E++ ++ +KP +E + T + V + E K P +
Sbjct: 4635 VPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEA 4694
Query: 267 IWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMS-AELT--V 323
KG +K + K S + + S G+K A T +
Sbjct: 4695 AKPKGP-------------IKGVPKK---TPSPIEAERRKLRPGSGGEKPPDEAPFTYQL 4738
Query: 324 LDEPLKFLGEMKPVKVTERQ----TAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSE 379
PLKF+ E+K + +TE + +A+FE +S W +G ++ K+
Sbjct: 4739 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIA-- 4796
Query: 380 DGLTHTLKIKDARLSDSGEFSA--EAGN--LVQKAQLTIDRIPIKFVSNL-KNVRVKERS 434
DG L I D +LSD+GE++ GN A+L ++ +P++FV L + V V +
Sbjct: 4797 DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQ 4856
Query: 435 RACLECELTSKDVTLRWKKDGQLLMHGT-KYSMNHEGKRAELIIEDAQLSDGGEYTVVAM 493
L CEL +K+ + W+KDG++++ + G L I DA +D G YT V +
Sbjct: 4857 PLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYT-VTV 4914
Query: 494 QDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEI 553
++ + E S+ + VE + + D H A + + W K EI
Sbjct: 4915 ENANNLE-CSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEI 4973
Query: 554 TDLPG--MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIAD 600
P +I++ G L + PE +Y +G A + + +
Sbjct: 4974 PAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGE 5022
Score = 85.9 bits (211), Expect = 2e-16
Identities = 147/715 (20%), Positives = 268/715 (37%), Gaps = 124/715 (17%)
Query: 72 KPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLT 131
KP+ +T EG+ A F G P ++W R+ + + SA+ + + ++ +
Sbjct: 26194 KPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQV-LSTSARHQVTTTKYKSTFEISSVQ 26252
Query: 132 SDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKR--------APPAPKKKQK 183
+ D NY + N +EG+++ +F ++K +PP K +
Sbjct: 26253 ASDEGNYSVVVEN-------------SEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEP 26299
Query: 184 KVANEKEMLEILS-KVPKKDFEKVCMEYGFTDFRGL-LRKLKEMKKKVEVEAIRILKPLE 241
+V + + + K P+ K T+ + K++ + + + LK
Sbjct: 26300 RVKSPEAVKSPKRVKSPEPSHPKAVSP---TETKPTPTEKVQHLPVSAPPKITQFLKAEA 26356
Query: 242 DKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVN 301
KE T VV ++ K+ + W K + L+ + ++ GT Y L I+N+
Sbjct: 26357 SKEIAKLTCVVESSVLRAKE----VTWYKDGKKLK-ENGHFQFHYSADGT-YELKINNLT 26410
Query: 302 MNDAGIYSLSVGDKRMSAE--LTVLDEPLKFLGEM------------------------- 334
+D G Y + + +++ L + + K + E
Sbjct: 26411 ESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP 26470
Query: 335 --------KPVKVTERQ--------TAVFEIRLS-KKEPNFVWKFNGKELKRDDKYEITV 377
KPV VT Q A F ++ + + P +W +GK + + KY++
Sbjct: 26471 KAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL-- 26528
Query: 378 SEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTIDRIP---IKFVSNLKNVRV 430
SED L+I SDSG ++ AG++ +LTI I + VS K +
Sbjct: 26529 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEI 26588
Query: 431 KERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTV 490
+ +A ++ E++ K + K + K ++ E + LI E+ + S
Sbjct: 26589 TPQKKAVVQEEISQKALRSEEIKMSEAKSQ-EKLALKEEASKV-LISEEVKKSAATSLEK 26646
Query: 491 VAMQDGDPTEYYSTAIVTVEERL-ATVKSGMSDVHAATGSPAELCVVLNDEKVEGV-WLK 548
+ + E T+ + E R A +K+ + + G L + N V W+
Sbjct: 26647 SIVHE----EITKTSQASEEVRTHAEIKAFSTQMSINEGQ--RLVLKANIAGATDVKWVL 26700
Query: 549 DGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTE---------------SE 593
+G E+T+ + G+ L EG T +K E S+
Sbjct: 26701 NGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSD 26760
Query: 594 ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEER 653
A FI+ P + + G G+P P++ W+K+ + ++
Sbjct: 26761 APAFISQP-------------RSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN 26807
Query: 654 VSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRV 708
VS+ R + L I N DSG +K KN G +AT L VL + P V
Sbjct: 26808 VSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREV 26862
Score = 83.6 bits (205), Expect = 1e-15
Identities = 80/296 (27%), Positives = 128/296 (43%), Gaps = 15/296 (5%)
Query: 417 IPIKFVSNLKNVRVKER----SRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKR 472
+P+KFV +K++ + E S A EC ++ W KDG + K+ +GK
Sbjct: 4741 VPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKD 4800
Query: 473 AELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAE 532
+L I D QLSD GEYT V ++ G+ + + +V E + VK+ +V G P
Sbjct: 4801 RKLHIIDVQLSDAGEYTCV-LRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 4859
Query: 533 LCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQ--GAVHKLIFPSMGPEHEGKYTFRAKGT 590
L LN E+ + VW KDGK + + PG +IV G + L G YT +
Sbjct: 4860 LSCELNKER-DVVWRKDGKIVVEKPG-RIVPGVIGLMRALTINDADDTDAGTYTVTVENA 4917
Query: 591 ES-EASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVT 649
+ E S + I +++ + VK TA K P + W+K E+
Sbjct: 4918 NNLECSSCVKVVEVIRDWLVKPIRDQ--HVKPKGTAIFACDI-AKDTPNIKWFKGYDEIP 4974
Query: 650 EE--ERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKP 703
E ++ + R + L I N + ED ++++ A TL ++ KP
Sbjct: 4975 AEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKP 5030
Score = 83.6 bits (205), Expect = 1e-15
Identities = 150/648 (23%), Positives = 250/648 (38%), Gaps = 101/648 (15%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
D+P P G +E L +S V ++W+ P+ +GG+ + + VE R G +W K + K
Sbjct: 24057 DKPSQP-GELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKD 24115
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-----EVFAGNPIEPPGFASQPQVTDV 813
F+ + E Y+FR+ A N G+S P T ++ +G E PG + ++ DV
Sbjct: 24116 KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSG---EAPGI--RKEMKDV 24170
Query: 814 TKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC---------TVD 864
T T+ G A L + R W K+ IQ K T+
Sbjct: 24171 T-----------TKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24219
Query: 865 GLLEDTEYE--FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ E+ E E + IA N+ G + S S ++ P PG + S++ L
Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETS--SKLLLQATPQFHPGYPLKEKYYGAVGSTLRLH 24277
Query: 923 WREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGT---CYTVGGLIERQKYF--FRIRA 977
P + + E I I T + V ++R+ + ++++
Sbjct: 24278 VMYIGRPVPAMTWFHGQKLLQNSE-----NITIENTEHYTHLVMKNVQRKTHAGKYKVQL 24332
Query: 978 VNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV- 1036
N G + + LD ++ P + A LK+ V+ S PP D
Sbjct: 24333 SNVFGTVDAI-LDVEIQDKPDKPTGPIVIEALLKNSAVI------------SWKPPADDG 24379
Query: 1037 -IWQKDGVPTK-----GRETITKSKNHSQF---LINSTKRSDSGVY-RILLQNEFGEAR- 1085
W + V K G E S S ++N T+ ++G Y R+ QN FG +
Sbjct: 24380 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDP 24437
Query: 1086 ---YDIHVRVADFPRP--PTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDAS 1138
+ + + F +P P + ++ + W P + G +Y + KR+
Sbjct: 24438 LEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWK--PPASDGGAKIRNYYLEKREKK 24495
Query: 1139 TATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDL 1197
W + E + ++V L+ G +Y FRV N G+SE W ++
Sbjct: 24496 QNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESE-------W-------SEI 24541
Query: 1198 SAKLKPYEKKDWR-HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITAN 1256
S + P K D AP F L+ V + T+ C G+P+P V Y+ I A+
Sbjct: 24542 SEPITP--KSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIAD 24599
Query: 1257 SKFW--YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
+ G L+I + T D+ Y V N+ G + +L V
Sbjct: 24600 GLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24647
Score = 75.5 bits (184), Expect = 3e-13
Identities = 142/714 (19%), Positives = 258/714 (36%), Gaps = 116/714 (16%)
Query: 14 VSMEFSSSTTHVQTFSQTTKIVGEEVVR---RKSSSIVEFFSLVTRSSNIPAGDSV---P 67
+S E +S T++Q Q K + E+V + K S S VTR + A + + P
Sbjct: 26421 ISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKP 26480
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
V Q T A F + G +P W ++ G I + K
Sbjct: 26481 VIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKD-GKAITQGGKY------------- 26526
Query: 128 EPLTSDDSDNYKCIASNDHADA-IYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
L+ D + I D +D+ +YT ++ + G K +K + +KV+
Sbjct: 26527 -KLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA----IKDTEAQKVS 26581
Query: 187 NEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETK 246
+K ++ KK V E I K L +E
Sbjct: 26582 TQKTS-----------------------------EITPQKKAVVQEEIS-QKALRSEE-- 26609
Query: 247 VDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAG 306
+KM K E L ++ K + + K + ++ +
Sbjct: 26610 -----------------IKMSEAKSQEKLALKEEASKVLISEEVKKS----AATSLEKSI 26648
Query: 307 IYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKE 366
++ + S E+ E F +M + E Q V + ++ + W NG E
Sbjct: 26649 VHEEITKTSQASEEVRTHAEIKAFSTQMS---INEGQRLVLKANIAGAT-DVKWVLNGVE 26704
Query: 367 LKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTIDRI---PI 419
L ++Y VS G TL IK A D G + + G + + LT+ +
Sbjct: 26705 LTNSEEYRYGVS--GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAP 26762
Query: 420 KFVSNLKNVRVKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIE 478
F+S ++ + E CE++ + + W K+ + + S++ L I
Sbjct: 26763 AFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIR 26822
Query: 479 DAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLN 538
+A +SD G+YT+ A ++ +V L V+ +V T L +
Sbjct: 26823 NASVSDSGKYTIKAKNFRGQCSATASLMV-----LPLVEEPSREVVLRTSGDTSLQGSFS 26877
Query: 539 DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFI 598
+ V+ + K+ ++ ++ F SM + S + + I
Sbjct: 26878 SQSVQ---MSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26934
Query: 599 ADPPTIDPSVLEALAAHA-------------ITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
++ ++ S + L A I++ G + F G+P P+VTW G
Sbjct: 26935 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26994
Query: 646 MEVTEEE--RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
++ +E R +E +D L I + ++D GL L L N+ GS +AT+++ +
Sbjct: 26995 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048
Score = 73.9 bits (180), Expect = 9e-13
Identities = 141/679 (20%), Positives = 253/679 (37%), Gaps = 92/679 (13%)
Query: 54 VTRSSNIPAGDSVP----EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIK 109
VT ++ +PA +P V + VT EG+ + G P ++W RE I+
Sbjct: 880 VTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYRED-YQIE 938
Query: 110 ESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKM 169
S + L + ++DS + C A N+ A + T L + E+ +
Sbjct: 939 SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNE-AGTVSTSCYLAVQVSEEFE---- 993
Query: 170 LKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKV 229
K+ EK E V +D V + T+ ++
Sbjct: 994 -----------KETTAVTEKFTTEEKRFVESRDV--VMTDTSLTE--------EQAGPGE 1032
Query: 230 EVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQM 289
I KP+ K + +VVF C + +P + W K PL Y KQ
Sbjct: 1033 PAAPYFITKPVVQKLVE-GGSVVFGCQVG-GNPKPHVYWKKSGVPLTTGYRYKVSYNKQT 1090
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKR--MSAELTVLDEP---LKFLGEMKPVKVTERQT 344
G + LVIS +DAG Y++ V +K SA ++L+E L + + + T+
Sbjct: 1091 G-ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTA 1149
Query: 345 AVFEIRLSKKEPNFVWKFNGKELKR---------------------DDKYEITVSEDGLT 383
V E ++ + P FV+ KE ++ D ++ I+ E+ L
Sbjct: 1150 FVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLI 1209
Query: 384 HTLKIKDARLSDSGEFSAEAGNLVQKAQLT-IDRIPIKFVSNLKNVRVKERSRACLECEL 442
++ + + + E E G ++ + + F S +KN R+ E C++
Sbjct: 1210 KEIEYRIIKTTLE-ELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKM 1268
Query: 443 TSKDVT-LRWKKDGQLLMHGTKYSMNH-EGKRAELIIEDAQLSDGGEYTVVAMQDGDPTE 500
+ + + W KDG+ + HG +Y M+ + RA L I D G YT A +
Sbjct: 1269 SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA------SN 1322
Query: 501 YYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQ 560
AI + + + + + T P L+ V I P
Sbjct: 1323 IKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSV------SRSPIRMSPARM 1376
Query: 561 IVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVK 620
+ + ++ M P + T ++ VF+ P + LE
Sbjct: 1377 SPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKP--VSFKCLE---------- 1424
Query: 621 VGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVREDSGLI 678
G TA + G+P+P+ W+ DG ++ + +V ++ Q+L+ + DSG
Sbjct: 1425 -GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVP-ATPSDSGEW 1482
Query: 679 LLKLKNDHGSATATLHLSV 697
+ +N G ++ ++ L+V
Sbjct: 1483 TVVAQNRAGRSSISVILTV 1501
Score = 71.2 bits (173), Expect = 6e-12
Identities = 150/685 (21%), Positives = 257/685 (37%), Gaps = 112/685 (16%)
Query: 52 SLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISW-KRESGIPIKE 110
S VT N P P+ +++ QPVT G A F A + G +P ISW K E +
Sbjct: 3181 SSVTLYVNAP---EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGF 3237
Query: 111 SAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKML 170
K +D +E+ L L +D+ Y C A ND+ A + SL V E E + + +
Sbjct: 3238 KCKFLHD--GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEM 3294
Query: 171 KKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVE 230
P Q V +E + +V D K+ K +
Sbjct: 3295 PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-----------------KVSWYSKDKK 3337
Query: 231 VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKY-DVKQM 289
++ R + + ++T +E+ + + +GT ++G+ +
Sbjct: 3338 IKPSRFFRMTQFEDTYQ---------LEIAEAYPE---DEGTYTFVASNAVGQVSSTANL 3385
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEI 349
+ N SLSV K+ L + F+ + ++V +T F
Sbjct: 3386 SLEGFSKFEENTSNSQWHVSLSVSFKK-----EPLGQKPSFIQPLSSLRVHNGETVRFHA 3440
Query: 350 RLSK-KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLK-IKDARLSDSGEFSAEAGNLV 407
R+S +P W F+ ++L K + E+ L I DA +G++S +A N
Sbjct: 3441 RVSGIPKPEIQW-FHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSA 3499
Query: 408 QKAQLTID-RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
+A + K ++ + R+++ E E+ K+ + + + +H + +
Sbjct: 3500 GEATCAATLTVTPKAPESILHERIEQ------EIEMEMKEFSSSFLSAEEEGLHSAELQL 3553
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYS----TAIVTVEERLATVKSGMSD 522
+ + EL LS+ Y PT++ S T + ++E +S+
Sbjct: 3554 SKINETLEL------LSESPVY---------PTKFDSEKEGTGPIFIKE--------VSN 3590
Query: 523 VHAATGSPAELCV-VLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEG 581
+ G A L V V+ K + W +G +T + V G H LI E EG
Sbjct: 3591 ADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEG 3650
Query: 582 KYTFRA----------------------KGTESEASVF-----IADPPTIDPSVLEALAA 614
+YT A K TE+E++V + P P L+ L
Sbjct: 3651 EYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGP--CPPHFLKEL-- 3706
Query: 615 HAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEV-TEEERVSMERGEDQALLTISNCVRE 673
I G A + G+P P VTW+K+ ++ T + +++ RE
Sbjct: 3707 KPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQRE 3766
Query: 674 DSGLILLKLKNDHGSATATLHLSVL 698
DSGL + K +N G +T L VL
Sbjct: 3767 DSGLYICKAENMLGESTCAAELLVL 3791
Score = 68.2 bits (165), Expect = 5e-11
Identities = 46/164 (28%), Positives = 76/164 (46%), Gaps = 7/164 (4%)
Query: 546 WLKDGKEITD--LPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA---KGTESEASVFIAD 600
W +DG+ I+ LPG+QI KL P++ + G+Y+ +A G + + +
Sbjct: 39 WFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
T P+ ++ L ++TV+ G ++V G P P V +Y+DG E+ + +
Sbjct: 99 AETAPPNFVQRL--QSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEG 156
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
D L I+ EDSG + N G AT+T L V + P
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Score = 67.4 bits (163), Expect = 9e-11
Identities = 105/466 (22%), Positives = 185/466 (39%), Gaps = 44/466 (9%)
Query: 867 LEDTEYEFRVIAVN---KAGPGQPSVPSSSV-----------VAKDPVKPPGLVQDLHVS 912
+E+TE+ ++ N K G+ V S+V + P KP G + +
Sbjct: 24305 IENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV---IE 24361
Query: 913 DSSNSSISLAWREPAE--GDPPSGYILEM-RAEDTKEWSKCTKIPISGTCYTVGGLIERQ 969
+S ++W+ PA+ G + Y++E A++ EW + TC V L E
Sbjct: 24362 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENA 24420
Query: 970 KYFFRIRAVNEAGVGEPVELDKGVRAMPP---PAAP-KFDLSARLKSHMVVRAGTALCIH 1025
Y+FR+ A N G+ +P+E+ V P P AP K ++A K VV A
Sbjct: 24421 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVV----AWKPP 24476
Query: 1026 AAFSGSPPPDVIWQK-DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEA 1084
A+ G+ + +K + K T+ + F + + +R+ +N GE+
Sbjct: 24477 ASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGES 24536
Query: 1085 RYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
+ +++ P +++ + + P+ N + Q + + WY
Sbjct: 24537 EWS---EISEPITPKSDVPI--QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR 24591
Query: 1145 AAERVFSN--KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLK 1202
+ + ++ KY + G Y+ ++A D+ R T N+ +A L+
Sbjct: 24592 QGKEIIADGLKYRIQEFKGG--YHQLIIASVTDDDATVYQVRAT---NQGGSVSGTASLE 24646
Query: 1203 PYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
E H P+ + + LRG+ ++ F G P P +T KG I N +
Sbjct: 24647 -VEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI 24705
Query: 1263 STSGVCTLVIPT-CTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
T +LV P KD+G Y V +N G D+ + L V D D
Sbjct: 24706 VTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPD 24751
Score = 62.8 bits (151), Expect = 2e-09
Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 1/115 (0%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P V+ LK TV+ G+ T+ C G P PTVT Y+ D I ++ F SG+ L+I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD-KSVVASITESLQKKSKHLM 1326
+DSG ++ NE G +SC L V ++ + ++TE + K +
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFV 1011
Score = 62.8 bits (151), Expect = 2e-09
Identities = 127/605 (20%), Positives = 241/605 (39%), Gaps = 84/605 (13%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P ++ + VT G+ A ++ G P I W R G + +S K S + H L
Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR-FGKELIQSRKYKMSSDGRTHTLT 24219
Query: 127 LEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
+ +D Y CIA+N+ + + T S L+ + + LK++ A +
Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGE-VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLR--- 24275
Query: 187 NEKEMLEILSKVPK----------KDFEKVCME----YGFTDFRGLLRKLKEMKKKVE-- 230
++ I VP ++ E + +E Y + + RK K KV+
Sbjct: 24276 --LHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLS 24333
Query: 231 -----VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTE---PLRIQYSLG 282
V+AI ++ ++DK K +V + +++ + + W + Y +
Sbjct: 24334 NVFGTVDAILDVE-IQDKPDKPTGPIVIEALLK---NSAVISWKPPADDGGSWITNYVVE 24389
Query: 283 KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDK---RMSAELTV-LDEPLKFLGEMKPVK 338
K + K+ G ++ LV S +++ I +L+ R+SA+ T + +PL+ +
Sbjct: 24390 KCEAKE-GAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKS 24448
Query: 339 VTERQTAVFE---IRLSKKEPNFVWK--------------FNGKELKRDDKYEITVSE-- 379
E+ A + ++K WK +E K++ +T E
Sbjct: 24449 PFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIR 24508
Query: 380 ----------DGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVR 429
+GL + ++K L E+S + + K+ + I F L+N+
Sbjct: 24509 ETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQ--APHFKEELRNLN 24566
Query: 430 VKERSRACLECELTSKDVTL-RWKKDG-QLLMHGTKYSMNH-EGKRAELIIEDAQLSDGG 486
V+ +S A L C++T + +W + G +++ G KY + +G +LII D
Sbjct: 24567 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDAT 24626
Query: 487 EYTVVAMQDGDPTEYYSTAIVTVEERLATVKS--GMSDVHAATGSPAELCVVLNDEKVEG 544
Y V A G ++ V V ++ K+ GM VHA G + + + +
Sbjct: 24627 VYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPV 24686
Query: 545 VWLKDGKEITDLPG-MQIVKQGAVHKLIFPSMGPEHE--GKYTFRAKG----TESEASVF 597
+ + G+++ D G Q++ + L+FP+ G E + G Y AK + +
Sbjct: 24687 ITWQKGQDLIDNNGHYQVIVTRSFTSLVFPN-GVERKDAGFYVVCAKNRFGIDQKTVELD 24745
Query: 598 IADPP 602
+AD P
Sbjct: 24746 VADVP 24750
Score = 59.7 bits (143), Expect = 2e-08
Identities = 70/309 (22%), Positives = 126/309 (40%), Gaps = 28/309 (9%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTK--GRETITKSKNHS 1058
AP F R ++ + G + SG P P++ W K+ +P +I++S+N
Sbjct: 26761 APAFISQPRSQN---INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVY 26817
Query: 1059 QFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNH 1118
I + SDSG Y I +N G+ + V L L EE V L +
Sbjct: 26818 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV---------LPLVEEPSREVVLRTSG 26868
Query: 1119 SPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+Q + + M A++ + FS+ + + + + + + + +S
Sbjct: 26869 DTSLQGSFSSQSVQMSASKQEASFSS-----FSSS-SASSMTEMKFASMSAQSMSSMQES 26922
Query: 1179 --EPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPH-TVLRGQDCTMTCA 1235
E S + N Q++ ++K+ K R P + L ++ G+ T+ CA
Sbjct: 26923 FVEMSSSSFMGISNMTQLESSTSKML---KAGIRGIPPKIEALPSDISIDEGKVLTVACA 26979
Query: 1236 FLGNPRPTVTLYKGDVNITANS--KFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGK 1293
F G P P VT G I + +F +T + TL+I +D G Y++ + NE G
Sbjct: 26980 FTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGS 27039
Query: 1294 DRSSCTLTV 1302
D ++ + +
Sbjct: 27040 DSATVNIHI 27048
Score = 57.4 bits (137), Expect = 9e-08
Identities = 77/307 (25%), Positives = 121/307 (39%), Gaps = 34/307 (11%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI--TKSKNHS 1058
AP+ L R++SH V G P +V W +GV + I T +
Sbjct: 26001 APRITL--RMRSHRVP-CGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVL 26057
Query: 1059 QFLINSTKRSDSGVYRILLQNEFGEAR--YDIHVRVADFPRPPTNLRLFEEVPNTVTLTW 1116
I DSG YR + N GEA + V D+ + R EEVP +V
Sbjct: 26058 TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRR-DEEVPRSVF--- 26113
Query: 1117 NHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIG 1176
P++ EA+ + + S ++ V S L ++ ++
Sbjct: 26114 ---PELTRT-EAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 26169
Query: 1177 DSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAF 1236
+ + L+ + T + K+K A R +T + TV G+ +C
Sbjct: 26170 EEKSLEEKST-----------TRKIKT------TLAARILTKPRSMTVYEGESARFSCDT 26212
Query: 1237 LGNPRPTVT-LYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDR 1295
G P PTVT L KG V ++ +++ +T T I + D G+YSV+VEN GK
Sbjct: 26213 DGEPVPTVTWLRKGQV-LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQE 26271
Query: 1296 SSCTLTV 1302
+ TLT+
Sbjct: 26272 AEFTLTI 26278
Score = 55.8 bits (133), Expect = 3e-07
Identities = 99/494 (20%), Positives = 176/494 (35%), Gaps = 85/494 (17%)
Query: 316 RMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYE 374
R+ A + + P + +K V V E ++ E +S P W +++ ++
Sbjct: 885 RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQ 944
Query: 375 ITVSEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTID----------RIPIK 420
IT + G+ L I++A DSG F+ EAG + L + + K
Sbjct: 945 ITF-QSGIAR-LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1002
Query: 421 FVSNLKNVRVKERSRACLECELTSKDVT-------------------------------- 448
F + K V+ R + LT +
Sbjct: 1003 FTTEEKRF-VESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1061
Query: 449 -----LRWKKDGQLLMHGTKYSMNHEGKRAE--LIIEDAQLSDGGEYTVVAMQDGDPTEY 501
+ WKK G L G +Y +++ + E L+I D GEYT+V T
Sbjct: 1062 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS- 1120
Query: 502 YSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQI 561
++A + E + ++ T A + E G + ++ + I
Sbjct: 1121 -ASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALI 1179
Query: 562 VKQGAVHKLIFPSMGPEHE-----------GKYTFRAKGT----------ESEASVFIAD 600
K+ A ++ + + E + +R T E + +V I++
Sbjct: 1180 RKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISE 1239
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
++ + + I +G T H K+ G PLPK+ WYKDG + ER M+ +
Sbjct: 1240 SEAVESGFDSRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQ 1297
Query: 661 D-QALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
D +A L I + ED G+ N G+A + L V P P G ++
Sbjct: 1298 DGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV--EPAAPLGAPTYIPTLEPVSR 1355
Query: 720 MKWKAPKDNGGRPV 733
++ +P+ P+
Sbjct: 1356 IRSLSPRSVSRSPI 1369
Score = 54.3 bits (129), Expect = 8e-07
Identities = 33/96 (34%), Positives = 41/96 (42%)
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
HAPR ++ H V GQ+ P V Y V + +SK Y +TSGV TL
Sbjct: 26000 HAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTL 26059
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKD 1306
I C DSG Y + N G+ TL V D
Sbjct: 26060 EILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGD 26095
Score = 52.8 bits (125), Expect = 2e-06
Identities = 66/296 (22%), Positives = 108/296 (36%), Gaps = 50/296 (16%)
Query: 251 VVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL 310
V + C +E D + ++ W G L + KY++ +L + ++ D G Y
Sbjct: 25213 VKYVCKIENYDQSTQVTWYFGVRQLE---NSEKYEITYEDGVAILYVKDITKLDDGTYRC 25269
Query: 311 SVGD-------------------------------KRMSAELTVLDEPLKFLGEMKPVKV 339
V + KR + + +L+ P +F +
Sbjct: 25270 KVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTA 25329
Query: 340 TERQTAVFEIRLS-KKEPNFVWKFNGKELKR-DDKYEITVSEDGLTHTLKIKDARLSDSG 397
+ F + ++ EP+ W +G+++K D+ + T D + L I D
Sbjct: 25330 YVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDA 25389
Query: 398 EFSAEAGNLVQ----KAQLTIDRIPIKFVSNLK--------NVRVKERSRACLECELTS- 444
E++ A N KA+LT+ P S L+ N +E C E ++
Sbjct: 25390 EYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGI 25449
Query: 445 KDVTLRWKKDGQLLMHGTKYSMNHEG-KRAELIIEDAQLSDGGEYTVVAMQDGDPT 499
TL+W+KDGQ L G + HEG L I D D G Y V A T
Sbjct: 25450 PPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGST 25505
Score = 52.4 bits (124), Expect = 3e-06
Identities = 70/313 (22%), Positives = 120/313 (38%), Gaps = 39/313 (12%)
Query: 999 PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-TKG---RETITKS 1054
PAAP F ++ + +V G ++ G+P P V W+K GVP T G + + K
Sbjct: 1033 PAAPYF-ITKPVVQKLV--EGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQ 1089
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+ +I+ T D+G Y I+++N+ GE + L EE + +
Sbjct: 1090 TGECKLVISMTFADDAGEYTIVVRNKHGET--------------SASASLLEEADYELLM 1135
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKY-YFRVVARN 1173
Q A ++ + TA + +E + +Y L +K VV R
Sbjct: 1136 KSQQEMLYQTQVTA-FVQEPKVGETAPGFVYSE--YEKEYEKEQALIRKKMAKDTVVVRT 1192
Query: 1174 EIGDSE-PLDSRDTWLINKDQIQDLSAKLKPYEKKDWRH------------APRFVTPLK 1220
+ D E + S + LI + + + + L+ ++D F + +K
Sbjct: 1193 YVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIK 1252
Query: 1221 PHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN-STSGVCTLVIPTCTLKD 1279
+ +L G T C G P P + YK I ++ + G +L IP +D
Sbjct: 1253 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312
Query: 1280 SGDYSVLVENELG 1292
G Y+ N G
Sbjct: 1313 EGIYTAFASNIKG 1325
Score = 52.4 bits (124), Expect = 3e-06
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFW--YNSTSGVCT 1269
AP F+T ++ G C GNP+P V K V +T ++ YN +G C
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
LVI D+G+Y+++V N+ G+ +S +L
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 51.2 bits (121), Expect = 6e-06
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 13/109 (11%)
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG----VP 1044
L G+R +PP L S + + G L + AF+G P P+V W G
Sbjct: 26948 LKAGIRGIPPKIEA-------LPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQ 27000
Query: 1045 TKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG--EARYDIHVR 1091
+GR I + + + +I ++ D G+Y + L NEFG A +IH+R
Sbjct: 27001 EQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 27049
Score = 50.8 bits (120), Expect = 8e-06
Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 8/197 (4%)
Query: 330 FLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKI 388
F ++ V V E TA FE +S P W +G+ + + +S L I
Sbjct: 8 FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTI 67
Query: 389 KDARLSDSGEFSAEA----GNLVQKAQLTI--DRIPIKFVSNLKNVRVKERSRACLECEL 442
++SG +S +A G A+L + + P FV L+++ V++ S+ L+ +
Sbjct: 68 PAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRV 127
Query: 443 TSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEY 501
T +++ +DG + + ++ EG L+I +A D G Y+V A
Sbjct: 128 TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATS 187
Query: 502 YSTAIVTVEERLATVKS 518
+ +V EE + K+
Sbjct: 188 TAELLVQGEEEVPAKKT 204
Score = 50.4 bits (119), Expect = 1e-05
Identities = 25/96 (26%), Positives = 49/96 (51%)
Query: 1207 KDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG 1266
K+ AP F++ + + GQ+ TC G P P + +K ++ I+ +S + +
Sbjct: 26756 KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN 26815
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
V +L I ++ DSG Y++ +N G+ ++ +L V
Sbjct: 26816 VYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851
Score = 50.1 bits (118), Expect = 1e-05
Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVRE 673
++ V G TA + G P+P+V+W++DG ++ V + + +A LTI +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 674 DSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
+SG LK N G AT+T L V PP
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 50.1 bits (118), Expect = 1e-05
Identities = 84/364 (23%), Positives = 140/364 (38%), Gaps = 55/364 (15%)
Query: 384 HTLKIKD-------ARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSN-LKNVRVKERSR 435
HTL KD AR+S G ++ G V A++ + I I VS + + +E
Sbjct: 25155 HTLIKKDLNMVVSAARISCGGAIRSQKG--VSVAKVKVASIEIGPVSGQIMHAVGEEGGH 25212
Query: 436 ACLECELTSKDVTLR--WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAM 493
C++ + D + + W + L + KY + +E A L ++D D G Y +
Sbjct: 25213 VKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 25272
Query: 494 QD-GDPTEYYSTAIVTVEE-------RLATVKSGMSDVHAATGSPAELCVVLNDEKV--- 542
D G+ + Y + V E R +D P E + L ++
Sbjct: 25273 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 25332
Query: 543 EGV---------------WLKDGKEITDLPGMQIVK-----QGAVHKLIFPSMGPEHEGK 582
E V W K G++I PG K +++L S+ + + +
Sbjct: 25333 ENVRFGVTITVHPEPHVTWYKSGQKIK--PGDNDKKYTFESDKGLYQLTINSVTTDDDAE 25390
Query: 583 YTFRAKGTESEAS------VFIADPPTIDP--SVLEALAAHAITVKVGHTAHIKVPFRGK 634
YT A+ E S V + PPT + + L A+A + G + ++ G
Sbjct: 25391 YTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANA-ECQEGQSVCFEIRVSGI 25449
Query: 635 PLPKVTWYKDGMEVTEEERVSM-ERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
P P + W KDG ++ + + G D L I + + ED+G + N GS +
Sbjct: 25450 PPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQA 25509
Query: 694 HLSV 697
HL V
Sbjct: 25510 HLQV 25513
Score = 48.9 bits (115), Expect = 3e-05
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P FV L+ TV +G + G P P V Y+ I ++ F + + +L+I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD------KSVV--ASITESLQKK 1321
+DSG YSV N +G+ S+ L V +++ K++V A I+ES Q +
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 48.9 bits (115), Expect = 3e-05
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 3/99 (3%)
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTK---GRETITK 1053
PP + + RL ++ + G ++C SG PPP + W+KDG P E I +
Sbjct: 25415 PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHE 25474
Query: 1054 SKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV 1092
++ I T D+G YR+ N G H++V
Sbjct: 25475 GLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25513
Score = 47.8 bits (112), Expect = 7e-05
Identities = 78/309 (25%), Positives = 120/309 (38%), Gaps = 29/309 (9%)
Query: 354 KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSD-SGEFSAEA----GNLVQ 408
KE N W F K + D+K++ +D T+TL I D GE+ EA G
Sbjct: 4395 KEVN--WYFENKLVPSDEKFKCL--QDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTAT 4450
Query: 409 KAQLTIDRIPIKFVSN-LKNVRVKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSM 466
A+LT+ + + ++ + V A CE+ S +V +W K G+ + K S+
Sbjct: 4451 SAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSI 4510
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
+ L I Q+ D GEYT A + +T VTV V+ + +
Sbjct: 4511 RSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPE 4570
Query: 527 TGSPAELCVVL------NDEKVEGVWLKDGKE--ITDLPGMQIVKQGAV-------HKLI 571
L VL + KVE L+ K+ + + P + V++ V K+
Sbjct: 4571 PKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIP 4630
Query: 572 FPSMGPEHEGKYTFRA--KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKV 629
P+ PE + A + EA V PP ++P A + V VG A K
Sbjct: 4631 EPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPV-VGKKAEAKA 4689
Query: 630 PFRGKPLPK 638
P PK
Sbjct: 4690 PKEEAAKPK 4698
Score = 47.8 bits (112), Expect = 7e-05
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA---NSKFWYNSTSGVCT 1269
P F PL T G++ +P P VT YK I + K+ + S G+
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25377
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L I + T D +Y+V+ N+ G+D LTV
Sbjct: 25378 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 47.4 bits (111), Expect = 9e-05
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSK-FWYNSTSGVCTL 1270
AP+ ++ TV +G D +G P P YK V I + + +WY VC L
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCEL 2090
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQ 1319
VI T +DS V N G+ S L V K + + T+ LQ
Sbjct: 2091 VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ----LITFTQELQ 2135
Score = 47.4 bits (111), Expect = 9e-05
Identities = 55/226 (24%), Positives = 100/226 (44%), Gaps = 30/226 (13%)
Query: 220 RKLKEMKKKVEVEAIRILK-------PLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGT 272
R +K++K++ + +R+L+ PL +K V V F + + P + W K
Sbjct: 25299 RTMKKIKRRTDT--MRLLERPPEFTLPLYNKTAYVGENVRFGVTITVH-PEPHVTWYKSG 25355
Query: 273 EPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPL 328
+ ++ + KY + Y L I++V +D Y++ G+ A+LTV P
Sbjct: 25356 QKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPP 25415
Query: 329 KFLGEMKPV--------KVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSE 379
++P+ + E Q+ FEIR+S P W+ +G+ L EI
Sbjct: 25416 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII--H 25473
Query: 380 DGLT-HTLKIKDARLSDSGEF----SAEAGNLVQKAQLTIDRIPIK 420
+GL + L I+D D+G + + AG+ +A L ++R+ K
Sbjct: 25474 EGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYK 25519
Score = 45.4 bits (106), Expect = 4e-04
Identities = 69/296 (23%), Positives = 111/296 (37%), Gaps = 39/296 (13%)
Query: 1032 PPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P +VIW K + + GR I +I + D+G Y L + + + +H
Sbjct: 6117 PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVH 6176
Query: 1090 VRVADFPRPPTNLRLFE-EVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAER 1148
A+F P NL + E E V S VQ KRD T
Sbjct: 6177 ELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQ---------WKRDDKTLE------- 6220
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKD 1208
+KY V + G+K R + L T+++ + +A L EK
Sbjct: 6221 -SGDKYDV--IADGKK-------RVLVVKDATLQDMGTYVVMVGAAR-AAAHLTVIEKL- 6268
Query: 1209 WRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVC 1268
R V PLK V Q+ C + ++ + I +SK+ V
Sbjct: 6269 -----RIVVPLKDTRVKEQQEVVFNCE-VNTEGAKAKWFRNEEAIFDSSKYIILQKDLVY 6322
Query: 1269 TLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASI--TESLQKKS 1322
TL I L D +Y+V + N G++ S + +++D +V + E+++KKS
Sbjct: 6323 TLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKS 6378
Score = 45.4 bits (106), Expect = 4e-04
Identities = 74/329 (22%), Positives = 131/329 (39%), Gaps = 40/329 (12%)
Query: 369 RDDKYEITVSEDGLTHTLKIKDARLSDSG--EFSAEAGNLVQKAQLTIDRIPIKFVSNLK 426
R+ K ++T + + L+ A + + E S E + +K + T+ + ++ +
Sbjct: 26140 REVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTL---AARILTKPR 26196
Query: 427 NVRVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDG 485
++ V E A C+ + V T+ W + GQ+L ++ + ++ I Q SD
Sbjct: 26197 SMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDE 26256
Query: 486 GEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGV 545
G Y+VV E T +T+++ T K+ S + P V + E V
Sbjct: 26257 GNYSVVVENSEGKQEAEFT--LTIQKARVTEKAVTSPPRVKSPEPR----VKSPEAV--- 26307
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
K K + + + K + P+ E K T TE + ++ PP I
Sbjct: 26308 --KSPKRVKS-------PEPSHPKAVSPT-----ETKPT----PTEKVQHLPVSAPPKI- 26348
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL- 664
L+A A+ I K+ V R K +VTWYKDG ++ E D
Sbjct: 26349 TQFLKAEASKEI-AKLTCVVESSV-LRAK---EVTWYKDGKKLKENGHFQFHYSADGTYE 26403
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATL 693
L I+N D G + ++ + G++ L
Sbjct: 26404 LKINNLTESDQGEYVCEISGEGGTSKTNL 26432
Score = 45.1 bits (105), Expect = 5e-04
Identities = 32/106 (30%), Positives = 42/106 (39%)
Query: 1197 LSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITAN 1256
++ K +P + P VT L+ TV G PRPT K IT
Sbjct: 26464 VTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG 26523
Query: 1257 SKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
K+ + G L I DSG Y+ V+N G SSC LT+
Sbjct: 26524 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26569
Score = 43.9 bits (102), Expect = 0.001
Identities = 40/196 (20%), Positives = 77/196 (39%), Gaps = 14/196 (7%)
Query: 509 VEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVH 568
++E + + + D + G L + + K E W + K + + ++ +
Sbjct: 4363 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAK-EVNWYFENKLVPSDEKFKCLQDQNTY 4421
Query: 569 KLIFPSMGPE-HEGKYTFRA------KGTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
L+ + E H+G+Y A T ++ +V P I + + V +
Sbjct: 4422 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKI------EPLEVAL 4475
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
GH A + P + W+K G E+ E ++ S+ + + L I D G K
Sbjct: 4476 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCK 4535
Query: 682 LKNDHGSATATLHLSV 697
N++GS + T L+V
Sbjct: 4536 ASNEYGSVSCTATLTV 4551
Score = 43.1 bits (100), Expect = 0.002
Identities = 46/213 (21%), Positives = 81/213 (38%), Gaps = 6/213 (2%)
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMS---DVHAATGSPAELCVVLNDEKVEGV 545
+V + G +AI T+++ L+ S V A T P+E V +
Sbjct: 776 SVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQF 835
Query: 546 WLKDGKEI-TDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
D + G+++ K+ V E + AK TE+ + P
Sbjct: 836 PFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVT 895
Query: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL 664
P+++ L +TV G + ++ G P P VTWY++ ++ + A
Sbjct: 896 PPTLVSGLKN--VTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIAR 953
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
L I EDSG N+ G+ + + +L+V
Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 43.1 bits (100), Expect = 0.002
Identities = 73/336 (21%), Positives = 119/336 (35%), Gaps = 70/336 (20%)
Query: 1030 GSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
G P P+ W DG V + + K +I SDSG + ++ QN G +
Sbjct: 1436 GRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSI 1495
Query: 1087 DI--HVRVADFPRPP--------TNLRLFEEVPNTVTLTWNHSPDVQ------------- 1123
+ V + P N++ + V T N +PD+
Sbjct: 1496 SVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKY 1555
Query: 1124 -------EDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTG-----------------L 1159
GEA I + + WYTA + + T +
Sbjct: 1556 PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLI 1615
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSR---DTWLINKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
+P Y + +A E+ EPL R + W + + D + KP+ KK +
Sbjct: 1616 IPRGTYRAKEIAAPEL---EPLHLRYGQEQW--EEGDLYDKEKQQKPFFKKK-------L 1663
Query: 1217 TPLKPHTVLRGQ-DCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
T L+ +C +T +G+P V + A ++ + G C+L
Sbjct: 1664 TSLRLKRFGPAHFECRLTP--IGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVA 1721
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVV 1311
+DSG + N+ G D +S TL V KD+KS+V
Sbjct: 1722 YSRDSGIITCRATNKYGTDHTSATLIV--KDEKSLV 1755
Score = 42.4 bits (98), Expect = 0.003
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 1198 SAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS 1257
SA K EK P F+ LKP +G +G P PTVT +K + + +
Sbjct: 3685 SAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSV 3744
Query: 1258 KFW-YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKD 1306
+ ++ +G T ++ +DSG Y EN LG+ + L V +D
Sbjct: 3745 YYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLED 3794
Score = 42.0 bits (97), Expect = 0.004
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 588 KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGME 647
K +E + V P T+D + L + V G + + KP +V WY +G+E
Sbjct: 25982 KTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVE 26041
Query: 648 VTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSAT--ATLHLS 696
+ E ++ L I +C +DSG N G A+ ATL ++
Sbjct: 26042 LQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVT 26092
Score = 40.0 bits (92), Expect = 0.015
Identities = 33/111 (29%), Positives = 45/111 (40%), Gaps = 15/111 (13%)
Query: 1002 PKFDLSARLKSHMV---VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE-----TITK 1053
P+F L K+ V VR G + +H P P V W K G K + T
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVH------PEPHVTWYKSGQKIKPGDNDKKYTFES 25371
Query: 1054 SKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRL 1104
K Q INS D Y ++ +N++GE + V P PPT+ L
Sbjct: 25372 DKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP-PPTDSTL 25421
Score = 39.7 bits (91), Expect = 0.019
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS--KFWYNSTSGVCT 1269
AP F PL+ VL G T G P P V+ ++ I+ ++ + + G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L IP T +SG YS+ N G+ S+ L V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 39.7 bits (91), Expect = 0.019
Identities = 62/301 (20%), Positives = 101/301 (33%), Gaps = 54/301 (17%)
Query: 1008 ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKS---KNHSQFLINS 1064
+R+K++ ++ G + H SG P P + W KDG K E + I
Sbjct: 1249 SRIKNYRILE-GMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPV 1307
Query: 1065 TKRSDSGVYRILLQNEFGEARYD--IHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDV 1122
D G+Y N G A ++V A PT + E V +L+
Sbjct: 1308 VLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLS------- 1360
Query: 1123 QEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
R S + + R+ + + + P R + L+
Sbjct: 1361 -----------PRSVSRSPIRMSPARMSPARMSPARMSPAR-----------MSPGRRLE 1398
Query: 1183 SRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP 1242
D + Q++ L + P FV L GQ +G P P
Sbjct: 1399 ETD-----ESQLERL-------------YKPVFVLKPVSFKCLEGQTARFDLKVVGRPMP 1440
Query: 1243 -TVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLT 1301
T + G + + G +L+I T DSG+++V+ +N G+ S LT
Sbjct: 1441 ETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILT 1500
Query: 1302 V 1302
V
Sbjct: 1501 V 1501
Score = 39.7 bits (91), Expect = 0.019
Identities = 42/183 (22%), Positives = 70/183 (38%), Gaps = 14/183 (7%)
Query: 9 MLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAG----- 63
+L E + E + + + G + S I E L++ S P
Sbjct: 3518 ILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEK 3577
Query: 64 -DSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKE 122
+ P F+++ GD A V G KP I W +G+ + SA + +
Sbjct: 3578 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFF-NGVLLTPSADYKFVFDGDD 3636
Query: 123 HVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV-TEGQEKMDFK------KMLKKRAP 175
H L + +D Y C+ASND+ I + L + ++G+ D + K L+K
Sbjct: 3637 HSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 3696
Query: 176 PAP 178
P P
Sbjct: 3697 PCP 3699
Score = 39.7 bits (91), Expect = 0.019
Identities = 32/131 (24%), Positives = 52/131 (39%), Gaps = 6/131 (4%)
Query: 52 SLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKES 111
S V +S G P F+++ +P+ +G A+F V G P ++W +E+ +
Sbjct: 3685 SAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENK---QLC 3741
Query: 112 AKIFYDSI---NKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKK 168
++Y I N + +DS Y C A N ++ LLV M
Sbjct: 3742 TSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 3801
Query: 169 MLKKRAPPAPK 179
K P AP+
Sbjct: 3802 CKAKSTPEAPE 3812
Score = 39.7 bits (91), Expect = 0.019
Identities = 49/220 (22%), Positives = 90/220 (40%), Gaps = 24/220 (10%)
Query: 80 EGDKAVFRARVQGNAKPHISWKRE-SGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNY 138
EG F RV G P + W+++ + + + +I ++ ++ + L + +D+ Y
Sbjct: 25436 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD-YYALHIRDTLPEDTGYY 25494
Query: 139 KCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANEKEMLEILS-- 196
+ A+N L V E++ +KK K + QK++ M EILS
Sbjct: 25495 RVTATNTAGSTSCQAHLQV----ERLRYKKQEFKSKEEHERHVQKQIDKTLRMAEILSGT 25550
Query: 197 ------KVPKKDFEKVCMEY----GFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETK 246
+V K+ + + Y +G R E+++K E +R+ + +
Sbjct: 25551 ESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFR--LEIEEKKEERKLRMPYDVPEPRKY 25608
Query: 247 VDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSL-GKYD 285
TT+ D ++ P M W K +R QY + GK D
Sbjct: 25609 KQTTIEEDQRIKQFVPMSDMKWYK---KIRDQYEMPGKLD 25645
Score = 39.3 bits (90), Expect = 0.025
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 3/89 (3%)
Query: 618 TVKVGHTAHIKVPFRGKPLPKVTWYKDGMEV---TEEERVSMERGEDQALLTISNCVRED 674
T VG V P P VTWYK G ++ +++ + E + LTI++ +D
Sbjct: 25328 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25387
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKP 703
+ +N +G + L+V P P
Sbjct: 25388 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 25416
Score = 38.5 bits (88), Expect = 0.043
Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 1/106 (0%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV-L 125
P F + Q V EG A F A + G P +SW R+ + + S + L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171
+ +T +S Y A+N A T LLV +F + L+
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ 111
Score = 38.5 bits (88), Expect = 0.043
Identities = 32/145 (22%), Positives = 60/145 (41%), Gaps = 10/145 (6%)
Query: 17 EFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGDSVPEFVEKPQPV 76
++ +++ + F + + V + RR I R+ + + PEF
Sbjct: 25274 DYGEDSSYAELFVKGVREVYDYYCRRTMKKIKR------RTDTMRLLERPPEFTLPLYNK 25327
Query: 77 TAPEGDKAVFRARVQGNAKPHISWKRESGIPIK---ESAKIFYDSINKEHVLKLEPLTSD 133
TA G+ F + + +PH++W + SG IK K ++S + L + +T+D
Sbjct: 25328 TAYVGENVRFGVTITVHPEPHVTWYK-SGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25386
Query: 134 DSDNYKCIASNDHADAIYTVSLLVT 158
D Y +A N + + L VT
Sbjct: 25387 DDAEYTVVARNKYGEDSCKAKLTVT 25411
Score = 37.7 bits (86), Expect = 0.074
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 81 GDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKC 140
G+ V G +P+ISW ++ G P+K++ ++ + VL ++ DD Y
Sbjct: 17954 GEDLKIEIPVIGRPRPNISWVKD-GEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 18012
Query: 141 IASNDHADAIYTVSLLVTE 159
A+N A +S++V E
Sbjct: 18013 TATNSAGTATENLSVIVLE 18031
Score = 37.4 bits (85), Expect = 0.096
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 1/98 (1%)
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
+ P V +P VL G+ C G P+P V Y I + +F G+
Sbjct: 1792 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHY 1850
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
L I C D+G+ V EN G L + ++D
Sbjct: 1851 LDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1888
Score = 37.0 bits (84), Expect = 0.13
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 1029 SGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG 1082
+G P P IW KDG + G+ +++ K I+ T SDSG+Y ++N G
Sbjct: 26504 TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAG 26559
Score = 35.8 bits (81), Expect = 0.28
Identities = 25/93 (26%), Positives = 36/93 (38%)
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
R AP ++P V G TC P +K I + K S+ + +
Sbjct: 4459 RAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISS 4518
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L I + D G+Y+ NE G + TLTV
Sbjct: 4519 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4551
Score = 35.4 bits (80), Expect = 0.37
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDG----VPTKGRETITKSKNHSQFLINSTKRSD 1069
+VV G+ A SG P P+V W +DG T I+ S ++ I + +++
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKAN 74
Query: 1070 SGVYRILLQNEFGEARYDIHVRVADFPRPP 1099
SG Y + N G+A + V PP
Sbjct: 75 SGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 35.4 bits (80), Expect = 0.37
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 4/119 (3%)
Query: 54 VTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAK 113
+T S++P P F E+ + + A +V G+ KP + W R+ I + K
Sbjct: 24545 ITPKSDVPI--QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 24602
Query: 114 I-FYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171
+ H L + +T DD+ Y+ A+N T SL V E K+ K L+
Sbjct: 24603 YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV-EVPAKIHLPKTLE 24660
Score = 34.3 bits (77), Expect = 0.82
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDG---VPTK-GRETITKSKNHSQFLINSTKRSDSG 1071
++ G+ L + +G+P PD++W K+ VP K + I +K + I+ST DS
Sbjct: 1521 IKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSA 1580
Query: 1072 VYRILLQNEFGE--ARYDIHVRVADFPRPPTNLRL 1104
Y N+ G R ++V V +F P +L
Sbjct: 1581 WYTATAINKAGRDTTRCKVNVEV-EFAEPEPERKL 1614
Score = 33.9 bits (76), Expect = 1.1
Identities = 30/134 (22%), Positives = 62/134 (46%), Gaps = 12/134 (8%)
Query: 296 VISNVNMNDAGIYSLSVGDKR-----MSAELTVLDEPLKFLGEMKPV----KVTERQTAV 346
VI+N+ + ++ + +++ S + ++ + L ++KP V Q
Sbjct: 16817 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 16876
Query: 347 FEIRLS-KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
E+ +S + +P W +G LK+ + +T S D LT TL IK+ D G++ N
Sbjct: 16877 IEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD-LT-TLSIKETHKDDGGQYGITVAN 16934
Query: 406 LVQKAQLTIDRIPI 419
+V + +I+ + +
Sbjct: 16935 VVGQKTASIEIVTL 16948
Score = 33.5 bits (75), Expect = 1.4
Identities = 36/161 (22%), Positives = 65/161 (40%), Gaps = 12/161 (7%)
Query: 973 FRIRAVNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGS 1031
+ ++A N +G EL PP + RL+S M VR G+ + + +G
Sbjct: 78 YSLKATNGSGQATSTAELLVKAETAPP------NFVQRLQS-MTVRQGSQVRLQVRVTGI 130
Query: 1032 PPPDVIWQKDGVPTKGR--ETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P P V + +DG + I++ + LI DSG Y + N G A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAE 190
Query: 1090 VRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHY 1130
+ V P + + + +T ++ + +++ EAH+
Sbjct: 191 LLVQGEEEVPA--KKTKTIVSTAQISESRQTRIEKKIEAHF 229
Score = 33.1 bits (74), Expect = 1.8
Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 76 VTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDS 135
V A GD V G KP ++WK+ I +K++ ++ +++ +L + DS
Sbjct: 14703 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQI-LKQTQRVNFETTATSTILNINECVRSDS 14761
Query: 136 DNYKCIASN 144
Y A N
Sbjct: 14762 GPYPLTARN 14770
Score = 33.1 bits (74), Expect = 1.8
Identities = 33/135 (24%), Positives = 53/135 (39%), Gaps = 17/135 (12%)
Query: 26 QTFSQT--TKIVGEEVVRRKSSSIVEFFSLVTR----SSNIPAGD-SVPEFVEKPQ---- 74
QT+S +K EV + K S++EF S + G +V E + P+
Sbjct: 21135 QTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLS 21194
Query: 75 -----PVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEP 129
VT G +G KP ISW ++ G+P+KES + + + L ++
Sbjct: 21195 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKD-GLPLKESEFVRFSKTENKITLSIKN 21253
Query: 130 LTSDDSDNYKCIASN 144
+ Y I N
Sbjct: 21254 AKKEHGGKYTVILDN 21268
Score = 33.1 bits (74), Expect = 1.8
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEF 399
P WK LK D+ IT ++D TL +KD+ DSG +
Sbjct: 22305 PKVTWKLEEMRLKETDRVSITTTKD--RTTLTVKDSMRGDSGRY 22346
Score = 32.7 bits (73), Expect = 2.4
Identities = 64/277 (23%), Positives = 104/277 (37%), Gaps = 48/277 (17%)
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEF---GEARYDIHVRV 1092
V W KDG K K K + G RIL+ N+ EA Y VR
Sbjct: 6032 VKWFKDGAEIK------KGKKYDII--------SKGAVRILVINKCLLDDEAEYSCEVRT 6077
Query: 1093 ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYII-MKRDASTATWYTAAERVF- 1150
A T L EE T L + +V E + + + + WY E +
Sbjct: 6078 ARTSGMLTVLE--EEAVFTKNLA---NIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIE 6132
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR--DTWLINKDQIQDLSAKLKPYEKKD 1208
+ +Y + L GRK V+ + D+ + R + K ++ +L+A+
Sbjct: 6133 TGRYEI--LTEGRKRIL-VIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAE-------- 6181
Query: 1209 WRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVC 1268
F++ + +L G+ C+ P V + D + + K+ +
Sbjct: 6182 ------FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKKR 6234
Query: 1269 TLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
LV+ TL+D G Y V+V G R++ LTV +K
Sbjct: 6235 VLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6267
Score = 32.3 bits (72), Expect = 3.1
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query: 280 SLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMK 335
SL K ++ + +L++ NVN D+G Y L+V G K + VLD P G +
Sbjct: 15529 SLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTP----GPPQ 15584
Query: 336 PVKVTE 341
+KV E
Sbjct: 15585 DLKVKE 15590
Score = 32.0 bits (71), Expect = 4.0
Identities = 15/54 (27%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 1247 YKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
Y DV + +N K+ S G L + T +D G+YS +++ + +++C L
Sbjct: 2254 YHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK----KTTCKL 2303
Score = 32.0 bits (71), Expect = 4.0
Identities = 57/243 (23%), Positives = 90/243 (37%), Gaps = 27/243 (11%)
Query: 1067 RSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDG 1126
RS+ V+ + L++ E ++ + DF T+ LF + P V T E+G
Sbjct: 5872 RSEGKVHTLTLRDVKLEDAGEVQLTAKDFK---THANLFVKEP-PVEFTKPLEDQTVEEG 5927
Query: 1127 EAHYII--MKRDASTATWY-TAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ + R+ + W+ E + S KY + GR V + I D P D
Sbjct: 5928 ATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVA--DGR------VRKLVIHDCTPEDI 5979
Query: 1184 RDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPT 1243
+ KD + + P + F+ PL V + C L
Sbjct: 5980 KTYTCDAKDFKTSCNLNVVPPHVE-------FLRPLTDLQVREKEMARFECE-LSRENAK 6031
Query: 1244 VTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVY 1303
V +K I K+ S V LVI C L D +YS E+ R+S LTV
Sbjct: 6032 VKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC----EVRTARTSGMLTVL 6087
Query: 1304 DKD 1306
+++
Sbjct: 6088 EEE 6090
Score = 32.0 bits (71), Expect = 4.0
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 11/70 (15%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAEL 321
PNV +W K LR + + D ++ L I N N ND+G Y+L++ + +A L
Sbjct: 19844 PNV--LWSKPDTDLRTRAYVDTTD-----SRTSLTIENANRNDSGKYTLTIQNVLSAASL 19896
Query: 322 T----VLDEP 327
T VLD P
Sbjct: 19897 TLVVKVLDTP 19906
Score = 32.0 bits (71), Expect = 4.0
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 9/70 (12%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P +W K L + + D+ + L + N N NDAG Y+L+V G K +
Sbjct: 22013 PTPTAVWSKPDSNLSL-----RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSI 22067
Query: 318 SAELTVLDEP 327
+ + VLD P
Sbjct: 22068 TFTVKVLDTP 22077
Score = 31.6 bits (70), Expect = 5.3
Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 11/129 (8%)
Query: 224 EMKKKVEVEAIRI-LKPLEDKETKVDTTVVFDCIME-LKDPNVKMIWIKGTEPLRIQYSL 281
E ++K+ ++ + +K +E K TTV F I+ + P K W ++
Sbjct: 11128 ECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTDEH- 11184
Query: 282 GKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMKPV 337
Y V+ +L I N D G Y ++V G K ++ LTVLD P G + +
Sbjct: 11185 --YTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINIL 11242
Query: 338 KVTERQTAV 346
VT +
Sbjct: 11243 DVTPEHMTI 11251
Score = 30.8 bits (68), Expect = 9.0
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
Query: 277 IQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPLKFLG 332
IQ SL + + Q G Y L+I+ D+G YS+ SVG +AEL V E
Sbjct: 144 IQSSLD-FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Query: 333 EMKPVKVTERQTAVFEIRLSKK 354
+ K + T + + + R+ KK
Sbjct: 203 KTKTIVSTAQISESRQTRIEKK 224
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 423 bits (1087), Expect = e-118
Identities = 299/1086 (27%), Positives = 497/1086 (45%), Gaps = 54/1086 (4%)
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTV------------SLLVTEGQEKMDFKK 168
++ +L ++ +D+ NY C + D V +L + EG EK +F
Sbjct: 6018 RKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEG-EKAEFVC 6076
Query: 169 MLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDF---EKVCMEYG-FTDFRGLLRKLKE 224
+ K + P K+ K + ++++ K+ + + G + G R
Sbjct: 6077 SISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAH 6136
Query: 225 MKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKY 284
+ +E +RI+ PL+D K VVF+C E+ K W + E + + KY
Sbjct: 6137 L---TVIEKLRIVVPLKDTRVKEQQEVVFNC--EVNTEGAKAKWFRNEEAI---FDSSKY 6188
Query: 285 DVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR-----MSAELTVLDEPLKFLGEMKPVKV 339
+ Q Y L I + +++D Y++S+ + R +A L V +E L+ + +K ++
Sbjct: 6189 IILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIET 6248
Query: 340 TERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEF 399
E+++ F ++++ W NG+E+ D++ V D H L IKD D GE+
Sbjct: 6249 MEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRV--DKYKHMLTIKDCGFPDEGEY 6306
Query: 400 SAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLM 459
AG A+L I P +FV +L++ V E A C+L+ + ++W ++G+ +
Sbjct: 6307 IVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIK 6366
Query: 460 HGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSG 519
G KY +G LII+D +L D EY ++D S A + VEE +
Sbjct: 6367 EGKKYKFEKDGSIHRLIIKDCRLDDECEYAC-GVEDRK-----SRARLFVEEIPVEIIRP 6420
Query: 520 MSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEH 579
D+ A G+ LN +KVE WL++ + Q++ +G +H+L + P
Sbjct: 6421 PQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRD 6480
Query: 580 EGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKV 639
+G+Y F AK E+ A + +A P I A + V VG + VP+ P +
Sbjct: 6481 QGEYRFIAKDKEARAKLELAAAPKIKT------ADQDLVVDVGKPLTMVVPYDAYPKAEA 6534
Query: 640 TWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLD 699
W+K+ ++ + +++ +Q I + D G + L+N HG A ++L V+D
Sbjct: 6535 EWFKENEPLSTK---TIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVID 6591
Query: 700 RPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVT 759
P P + +E E V + W+ P +GG + ++VERR + +K+W+ +
Sbjct: 6592 VPGPVRN-LEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCE 6650
Query: 760 NFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAV 818
T + G Y FR+ A N G +P+ET+ V A + + PG +TDV + V
Sbjct: 6651 FTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGV 6710
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
++TW P DGGA + Y++E R K S W + TV ++E EY FRV A
Sbjct: 6711 SLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRA 6770
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYI 936
N+ G G+PS + V DP++ P +L SD + SS+ L W P + G P GYI
Sbjct: 6771 QNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 6830
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
+E E W +C + Y V GL + KY +R+ A N+AGV +P E+ + A
Sbjct: 6831 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 6890
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIW--QKDGVPTKGRETITKS 1054
P DLSA K + V + I +G P P W + T R +
Sbjct: 6891 DAFVEPTMDLSA-FKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTL 6949
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+++ +I+ ++RSD G+Y + L+N +I V V P P L+ + ++V L
Sbjct: 6950 SAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHL 7009
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNE 1174
TW D Y++ KR+ S TW + V ++TV L+ G++Y F+V ARN+
Sbjct: 7010 TWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNK 7069
Query: 1175 IGDSEP 1180
G EP
Sbjct: 7070 CGPGEP 7075
Score = 380 bits (977), Expect = e-105
Identities = 300/1056 (28%), Positives = 483/1056 (45%), Gaps = 93/1056 (8%)
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+MG KY ++ VN+ YS S+ + + + D L+ ++K VT R A
Sbjct: 22911 KMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD--LELADDLKKT-VTIRAGASL 22967
Query: 348 EIRLS---KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKD-ARLSDSGEFSAEA 403
+ +S + P W G +L + T S ++L I D D+G+++ EA
Sbjct: 22968 RLMVSVSGRPPPVITWSKQGIDLASRAIIDTTES-----YSLLIVDKVNRYDAGKYTIEA 23022
Query: 404 GNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWK---KDGQLLMH 460
N K T+ +V+VKE SR VT+ W+ DG ++
Sbjct: 23023 ENQSGKKSATVLVKVYDTPGPCPSVKVKEVSR---------DSVTITWEIPTIDGGAPVN 23073
Query: 461 GTKYSMNHEGKRA---------ELIIEDAQLSDGGEYTVVAMQD-----GDPTEYYSTAI 506
RA + + + L +G Y + + G+P E S A+
Sbjct: 23074 NYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE-TSDAV 23132
Query: 507 VTVEERLATVKSGMSDVHAATGSPA-ELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQG 565
+ E L K + DV +T + A E + ++ G L+ K T+ + +
Sbjct: 23133 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23192
Query: 566 AVHKLIFPSMGPEHEGKYTFRAKG-------TESEASVFIAD---PPTIDPSVLEALAAH 615
V + S+ + + RA+ E+ +V + D PTID S + H
Sbjct: 23193 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIH 23252
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDS 675
V G + +P G+P P +W+ G ++ E ERV++E A LTI D+
Sbjct: 23253 ---VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDT 23309
Query: 676 GLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQ 735
G L+LKN G+ + T+ + +LD+P PP G ++ E+ + + + W+ P+ +GG P++
Sbjct: 23310 GEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSG 23369
Query: 736 FIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFA 795
++VE+R + W+ + E + T F ++ EG Y FR+ A N G+ L++E +
Sbjct: 23370 YVVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIEC 23428
Query: 796 GNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP 855
+ I PG Q+ DV+++ +T+TW P DGG+ V GYIVER++ ++ WV VNK P
Sbjct: 23429 RSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVP 23488
Query: 856 IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSS 915
+ T+ GL E EYE RV A+N G G+PS PS +VA DP+ PPG Q+ V+D++
Sbjct: 23489 VTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTT 23548
Query: 916 NSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFF 973
+S+SLAW P + G +GY++EM+ D EW+KC P YT+ L + +Y F
Sbjct: 23549 RTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRF 23608
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
R+ A N G GEP E+ V+ P ++L R + + VR G + + G P
Sbjct: 23609 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPF 23668
Query: 1034 PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVA 1093
P W K+G R I S+ H++ +I R DSG Y ++L+N+ G+ I VRV
Sbjct: 23669 PICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVI 23728
Query: 1094 DFPRPPTNLRLFEEVP-NTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERV 1149
P P ++++ +V ++W D DG A YI+ +R+ A WYT RV
Sbjct: 23729 GSPNSPEGPLEYDDIQVRSVRVSWRPPAD---DGGADILGYILERREVPKAAWYTIDSRV 23785
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
V GL +Y+FRV A N+ G S+PL S + P K
Sbjct: 23786 RGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE-----------------PVTPKTP 23828
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP------TVTLYKGDVNITANSKFWYNS 1263
+ P P P VL D T + L RP VT Y + T+ K+ ++
Sbjct: 23829 LNPPE--PPSNPPEVL---DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHN 23883
Query: 1264 TSGVCTLVIPTCTLKDSGDYS--VLVENELGKDRSS 1297
+ + T + L +Y ++ +N++G +S
Sbjct: 23884 KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETS 23919
Score = 377 bits (967), Expect = e-104
Identities = 245/766 (31%), Positives = 380/766 (49%), Gaps = 52/766 (6%)
Query: 448 TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIV 507
+L W K L+ T+Y + E L+ G + PTEY
Sbjct: 12638 SLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG-----SSPPSKPTEY------ 12686
Query: 508 TVEERLATVKSGMSDVHAATGSPAELCVVL----NDEKVEGVWLKDGKEITDLPGMQIVK 563
V R+ G +V T S L K+ G ++ E LPG + V+
Sbjct: 12687 -VTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFV----EACKLPGDKWVR 12741
Query: 564 -QGAVHKLI---FPSMGPEHEGKYTFRA----------KGTESEASVFIAD--PPTIDPS 607
A H++ + + G E + +Y FRA S+ +A+ PP ID S
Sbjct: 12742 CNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS 12801
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
V +TVK G + GKP+P V+W KDG + E + M + L +
Sbjct: 12802 VA---MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLEL 12858
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKD 727
+ R+DSG + +N GS +AT+ L VLD+P PP V+ ++ + W+ P +
Sbjct: 12859 FSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPAS-VKINKMYSDRAMLSWEPPLE 12917
Query: 728 NGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP 787
+GG +T +IV++R + +W ++ +T+ S K+ EG YQFRI A N GV DP
Sbjct: 12918 DGGSEITNYIVDKRETSRPNWAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDP 12976
Query: 788 LETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNL 847
+ TE A NP +PPG P ++++TK+ +T++W P DGG+P+ GY++E+R+ +
Sbjct: 12977 VFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVN 13036
Query: 848 WVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
W VN+ PI GL E TEYEFRV A+NKAGPG+PS S + A+DP PPG
Sbjct: 13037 WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPA 13096
Query: 908 DLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIP--ISGTCYTVG 963
V D++ SS+SL+W +PA G P GY++E++ D+ W +C +P + T + V
Sbjct: 13097 FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRC-NLPQNLQKTRFEVT 13155
Query: 964 GLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC 1023
GL+E +Y FR+ AVN+ G +P ++ P+ +L A L+ +++RAG +
Sbjct: 13156 GLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMR 13215
Query: 1024 IHAAFSGSPPPDVIWQKDGVPTKGRETI-TKSKNHSQFL-INSTKRSDSGVYRILLQNEF 1081
++ G PPP + W K V + R + KS + FL + + D+G Y + L+N
Sbjct: 13216 LYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSC 13275
Query: 1082 GEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDAST 1139
G+ Y I V+V D P PP N+ + E ++ +TW P + + G +Y++ KRDA
Sbjct: 13276 GKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTW--EPPIIDGGSPIINYVVQKRDAER 13333
Query: 1140 ATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+W T + V L G+ Y+FRV A NE G +P ++RD
Sbjct: 13334 KSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRD 13379
Score = 372 bits (954), Expect = e-102
Identities = 280/973 (28%), Positives = 457/973 (46%), Gaps = 72/973 (7%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRM 317
P + W+K EPL+ + +V++ T +L I N +D G Y++ S G
Sbjct: 17842 PRPNISWVKDGEPLK---QTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATE 17898
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVW--KFNGKELKRDDKYEI 375
+ + VL++P +G PV+ E +A F + +S + P + + + +++ D
Sbjct: 17899 NLSVIVLEKPGPPVG---PVRFDE-VSADFVV-ISWEPPAYTGGCQISNYIVEKRDTTTT 17953
Query: 376 T---VSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKA-----QLTIDRIPIK------- 420
T VS T+KI + +F A N K+ + I + P K
Sbjct: 17954 TWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGT 18013
Query: 421 -FVSNLKNVR--------VKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMN--H 468
FV+++ + V + + L K+ ++ W K + + TK+
Sbjct: 18014 PFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLD 18073
Query: 469 EGKRAELIIEDAQLSDGGEYT-----VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
EG E + + G+ + VA DP ++T K D
Sbjct: 18074 EGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYD- 18132
Query: 524 HAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVH--KLIFPSMGPEHEG 581
GS +V + +G W+K T++ + G V + F + G
Sbjct: 18133 ---GGSKITGYIVEKKDLPDGRWMK--ASFTNVLETEFTVSGLVEDQRYEFRVIARNAAG 18187
Query: 582 KYTFRAKGTESEASVFIADPP--TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKV 639
++ + + + + D P ++DP + + HA G T ++ RGKP+P V
Sbjct: 18188 NFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA-----GETFVLEADIRGKPIPDV 18242
Query: 640 TWYKDGMEVTEEE-RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVL 698
W KDG E+ E R+ ++ + L + +C+R D G +LKL N G+ + + + VL
Sbjct: 18243 VWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVL 18302
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
DRP PP+G ++ ++ ++ W P +GG ++ +I+E+R + SW ++ + +
Sbjct: 18303 DRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVS-TEVQA 18361
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAV 818
N+ K+ G Y FR++AVN G+ +PLE+ V A NP +PPG S P+V+ +TK+++
Sbjct: 18362 LNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSM 18421
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
+TW P DGG + GYI+E+R K W NK + + V GL E YEFRV A
Sbjct: 18422 VVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAA 18481
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYI 936
N AG G+PS PS A D + PPG + V+D+S SS+SLAW +P G P GY+
Sbjct: 18482 ENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYV 18541
Query: 937 LEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRA 995
+E++ EW+ CT + G +TV L E +Y FRI A+N GVGEP L V A
Sbjct: 18542 VEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVA 18601
Query: 996 MPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKGRETITKS 1054
P+ +L A L+ +V+RA L + G P P+V W+K +G+ T R I +
Sbjct: 18602 QERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT-DRAQIEVT 18660
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+ + +I++ R DSG Y + L+N G ++VRV D P P NL + E ++VTL
Sbjct: 18661 SSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTL 18720
Query: 1115 TWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVAR 1172
+W P + + G +YI+ KR+ + + T + + L G YYFRV+A
Sbjct: 18721 SW--EPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLAS 18778
Query: 1173 NEIGDSEPLDSRD 1185
NE G P ++ +
Sbjct: 18779 NEYGIGLPAETTE 18791
Score = 369 bits (946), Expect = e-101
Identities = 203/577 (35%), Positives = 321/577 (55%), Gaps = 11/577 (1%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ + G + ++ GKP P + WYKD E+ V +E D A + I + R +SG
Sbjct: 20385 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20444
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
LKL+N GSA+AT+ + +LD+P PP G +EF ++ + + W+ P D+GG +T +
Sbjct: 20445 CYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHY 20504
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
IVE+R + W + E + +T K+ +G Y FR+ AVN G+ +PLE++ V A
Sbjct: 20505 IVEKRETSRVVWSMVSEHLEECI-ITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAK 20563
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N PG P+VT +TK ++T+ W+ P DGG+ + GY +E+R K S W V K+ I
Sbjct: 20564 NAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETI 20623
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ T+ V GL E+++Y++RV AVN AG G S PS A DP+ PPG + ++DS+
Sbjct: 20624 RDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 20683
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSK-CTKIPISGTCYTVGGLIERQKYFF 973
SSI+L W +P G +GY++E+R + +EW+ TK + T Y V L Y+F
Sbjct: 20684 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 20743
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
R+ AVN AG GEP+E+++ V+A AP+ DL L++ ++ +AG + + F G PP
Sbjct: 20744 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPP 20803
Query: 1034 PDVIWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYD-IHV 1090
P V W+KD + + R +I + + S I R+D+G Y + ++N GE + + V
Sbjct: 20804 PTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSV 20863
Query: 1091 RVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAER 1148
+V D P L++ TVTL W+ P + + G +Y+I KRDA+ TW + +
Sbjct: 20864 KVLDTPAACQKLQVKHVSRGTVTLLWD--PPLIDGGSPIINYVIEKRDATKRTWSVVSHK 20921
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
S + + L ++FRV+A NEIG EP ++ +
Sbjct: 20922 CSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTE 20958
Score = 361 bits (927), Expect = 2e-99
Identities = 200/602 (33%), Positives = 315/602 (52%), Gaps = 12/602 (1%)
Query: 590 TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVT 649
+ES + + D +++ I VK G I G+PLP ++W KDG+E+
Sbjct: 19275 SESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE 19334
Query: 650 EEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVE 709
E R + ++ LLT+ +C+R D+G +L LKN G+ + ++ VLD+P PP G +E
Sbjct: 19335 ERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLE 19394
Query: 710 FLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEG 769
L+ + W P+++GG + +IVE+R +W I E + ++T+ K+ +G
Sbjct: 19395 INGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT-ICEGELQMTSCKVTKLLKG 19453
Query: 770 KAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDG 829
Y FR+ VN GV +PLE+ + A +P P + ++T VTKE++T+ W+ P DG
Sbjct: 19454 NEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDG 19513
Query: 830 GAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSV 889
G+ + GYI+ERR+K S WV VNK P+ + GL E EYE+RV A N AG PS
Sbjct: 19514 GSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSE 19573
Query: 890 PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEW 947
S + A+DPV P + DS ++I++AW +P G P +GY +E + D +W
Sbjct: 19574 TSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW 19633
Query: 948 SKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLS 1007
K + + GT YT+ GL +Y FR+++VN+ G +P + A P FD+
Sbjct: 19634 -KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDID 19692
Query: 1008 ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKR 1067
+ ++ ++V+AG + + F G P P+V+W K + R + + + + I + R
Sbjct: 19693 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANR 19752
Query: 1068 SDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQE-DG 1126
+DSG Y + +QN A + V+V D P PPTN+ + + + L+W DV E DG
Sbjct: 19753 NDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSW----DVPENDG 19808
Query: 1127 EA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
A +Y I KR+AS W + Y VT L G YYFRV NE G P ++
Sbjct: 19809 GAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAET 19868
Query: 1184 RD 1185
++
Sbjct: 19869 KE 19870
Score = 358 bits (918), Expect = 2e-98
Identities = 222/650 (34%), Positives = 334/650 (51%), Gaps = 19/650 (2%)
Query: 552 EITDLPGMQIVKQGAVH--KLIFPSMGPEHEGKYTFR--AKGT--------ESEASVFIA 599
E DLP +K V+ + F GKY FR AK T ES ++
Sbjct: 13814 EKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICK 13873
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIK-VPFRGKPLPKVTWYKDGMEVTEEERVSMER 658
D VL+ +T+K G T + + GKPLPK +W K G ++ + +
Sbjct: 13874 DEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITS 13933
Query: 659 GEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCV 718
++LTI R+D+G + N G+ + ++VLD P PP G VE +S
Sbjct: 13934 TPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKA 13992
Query: 719 HMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILA 778
+ W P ++GG P+ +I+E+R + W + E D + K+ +G Y FR+ A
Sbjct: 13993 TLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSE-DIQSCRHVATKLIQGNEYIFRVSA 14051
Query: 779 VNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
VN G +P+++E V + PPG +P+V++VTK T++W P DGG+ + GY V
Sbjct: 14052 VNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14111
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
ERR+K S WV K P+ +C V GL E + YEFRV A N+AG G PS S SV+ KD
Sbjct: 14112 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14171
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPPSGYILEMRAEDTKEWSK-CTKIPI 955
PPG + HV+D++ S SLAW +P G +GY++E + + W K T +
Sbjct: 14172 AAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTAL 14231
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
T + V L ++KY FRI A+N+AGVGEP + V + AP F+L A L+ +V
Sbjct: 14232 RITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI-PDVEIVEREMAPDFELDAELRRTLV 14290
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
VRAG ++ I G P P+V W KD + K R I +++ + +I R D+G + +
Sbjct: 14291 VRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 14350
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
++N G+ ++VRV D P P NLR + ++VTL W+ +YI+ KR
Sbjct: 14351 TIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKR 14410
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+A+ ++ TA + Y VTGL G +Y+FRV+A NE G EP ++ +
Sbjct: 14411 EATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTE 14460
Score = 355 bits (910), Expect = 2e-97
Identities = 278/985 (28%), Positives = 444/985 (45%), Gaps = 97/985 (9%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P + W K PL+ + D + T L I + +D G Y ++V G K
Sbjct: 16760 PKPTITWTKDGLPLKQTTRINVTDSLDLTT---LSIKETHKDDGGQYGITVANVVGQKTA 16816
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKF---NGKELKRDDKYE 374
S E+ LD+P G PVK + + I LS P + N KRD
Sbjct: 16817 SIEIVTLDKPDPPKG---PVKFDD--VSAESITLSWNPPLYTGGCQITNYIVQKRDTTTT 16871
Query: 375 I--TVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV-QKAQLTIDRIPIKF---------- 421
+ VS TLK+ + +F A N Q L D I ++
Sbjct: 16872 VWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGT 16931
Query: 422 -----VSNLKNV-----RVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEG 470
+S V V + L K+ ++ W K + ++H T++ +
Sbjct: 16932 PFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQN-- 16989
Query: 471 KRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMS-DVHAATGS 529
L +G EY Y+ IV V + + ++ D G+
Sbjct: 16990 -----------LEEGIEYEF---------RVYAENIVGVGKASKNSECYVARDPCDPPGT 17029
Query: 530 PAELCVVLNDEKVEGVWLKD----GKEIT-------DLPGMQIVKQGAVHKLI--FPSMG 576
P + V N+ ++ W K G IT DLP + +K + + F G
Sbjct: 17030 PEPIMVKRNEITLQ--WTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSG 17087
Query: 577 PEHEGKYTFR----------AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAH 626
+ +Y FR +K ++S + D + ++ I V G T
Sbjct: 17088 LTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFR 17147
Query: 627 IKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDH 686
++ GKPLP + W + E+ E R ++ + +ALL + + +R D G +L+ N
Sbjct: 17148 LEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA 17207
Query: 687 GSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKK 746
GS + +++ VLDRP PP+G V+ ++ + W P +GG ++ ++VE+R +
Sbjct: 17208 GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRL 17267
Query: 747 SWIKIGEVDGKVTN-FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFA 805
+W + VTN K+ EG Y FRI+AVN GV +PLE+ V NP PG
Sbjct: 17268 AWTVVASE--VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPP 17325
Query: 806 SQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDG 865
+VT++ K+++T+ WN P DGG+ ++GYIVE+R + W+ NK I + V G
Sbjct: 17326 KSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTG 17385
Query: 866 LLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWRE 925
L ED EYEFRV A N AG G+PS + A DPV PG + H+ D++ +SI+LAW +
Sbjct: 17386 LTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGK 17445
Query: 926 PA--EGDPPSGYILEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAG 982
P G GY++E+ D +EW T + + T + + L E Q+Y R+ A+N+ G
Sbjct: 17446 PIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVG 17505
Query: 983 VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG 1042
+GE + V+ AP+ DL + L+ +VVRAG + IH F G P P++ W ++
Sbjct: 17506 LGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREE 17565
Query: 1043 VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNL 1102
+ I K N++Q I++ R+D+G Y + L+N G + V+V D P PP NL
Sbjct: 17566 GEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNL 17625
Query: 1103 RLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLL 1160
+ E ++ L W P + + G +Y+I KR+++ + + + + V L
Sbjct: 17626 AVKEVRKDSAFLVW--EPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLT 17683
Query: 1161 PGRKYYFRVVARNEIGDSEPLDSRD 1185
G YYFRV+A NE G P+++ D
Sbjct: 17684 EGAIYYFRVMAENEFGVGVPVETVD 17708
Score = 352 bits (902), Expect = 2e-96
Identities = 208/628 (33%), Positives = 317/628 (50%), Gaps = 22/628 (3%)
Query: 580 EGK-YTFRA-------KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPF 631
EGK YTFR +GT SE +V D L+ L K +K+P
Sbjct: 13450 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13509
Query: 632 RGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATA 691
+GKP P V+W K + + RVS+E L + +C + D+G + LKN G+
Sbjct: 13510 KGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEG 13569
Query: 692 TLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKI 751
T+ + V+ +P P G ++F E++ + +KW PKD+GG +T +I+E+R W+
Sbjct: 13570 TISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTC 13629
Query: 752 GEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVT 811
K T F ++ EG Y FR+ A N GV + L++E + A +P + P P +
Sbjct: 13630 ASAVQKTT-FRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIV 13688
Query: 812 DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTE 871
DV ++V++TW P + GG+P+ GY +E +++ S LW NK PI+ V GL E E
Sbjct: 13689 DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLE 13748
Query: 872 YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EG 929
YEFRV+A+N AG G+PS+PS VVA DP+ PPG + +++ + +S++L W EP G
Sbjct: 13749 YEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINI---TRNSVTLIWTEPKYDGG 13805
Query: 930 DPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVE 988
+GYI+E R +K W K + + +TV L+E KY FRIRA N AG + P E
Sbjct: 13806 HKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSE 13865
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHA-AFSGSPPPDVIWQKDGVPTKG 1047
+ + AP L +K + ++AG + ++A + G P P W K G +
Sbjct: 13866 STETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRP 13925
Query: 1048 RE--TITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLF 1105
+ IT + S I R D+G Y I N FG + V V D P PP + +
Sbjct: 13926 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEIS 13985
Query: 1106 EEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGR 1163
TLTW +P +++ G YI+ KR+ S W +E + S ++ T L+ G
Sbjct: 13986 NVSAEKATLTW--TPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGN 14043
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINK 1191
+Y FRV A N G EP+ S ++++
Sbjct: 14044 EYIFRVSAVNHYGKGEPVQSEPVKMVDR 14071
Score = 352 bits (902), Expect = 2e-96
Identities = 217/667 (32%), Positives = 334/667 (50%), Gaps = 19/667 (2%)
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAV--HKLIFPSMGPEHEGKYTF 585
GS +V E EG W+K T++ G V H+ F + G ++
Sbjct: 15970 GSKITGYIVEKKELPEGRWMK--ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSE 16027
Query: 586 RAKGTESEASVFIADPPTI--DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYK 643
++ T + + DPP I DP + + HA G + + GKP+P + W K
Sbjct: 16028 PSESTGAITARDEVDPPRISMDPKYKDTIVVHA-----GESFKVDADIYGKPIPTIQWIK 16082
Query: 644 DGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKP 703
E++ R+ ++ + L++ + VR DSG +LK KN G + T+++ VLDRP P
Sbjct: 16083 GDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP 16142
Query: 704 PQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFST 763
P+G V ++ + WK P +GG + +IVERR + W + + + + +
Sbjct: 16143 PEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV-DANVQTLSCKV 16201
Query: 764 NKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWN 823
K+ EG Y FRI+AVN GV +PLE+E V A NP P P+VT VTK+++ + W
Sbjct: 16202 TKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWE 16261
Query: 824 APTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAG 883
P DGG+ +LGY++E+R K W +K I + V GL+E+ +YEFRV A N AG
Sbjct: 16262 RPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAG 16321
Query: 884 PGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRA 941
+PS PS+ A DP+ PG + V D + SS+ L+W +P G GYI+E
Sbjct: 16322 LSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCD 16381
Query: 942 EDTKEWSKCT-KIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPA 1000
EW+ CT I+ T V L+E+ +Y FRI A+N+AGVGE ++ +
Sbjct: 16382 VSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLE 16441
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
AP DL L+ + +RAG +L + G P P+V W K + I + + +
Sbjct: 16442 APDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSL 16501
Query: 1061 LINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
++++ R DSG Y + L+N G + VRV D P PP NL++ E ++V++TW P
Sbjct: 16502 VLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW--EP 16559
Query: 1121 DVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+ + G +YI+ KR+A+ ++ N + + L G YYFRV A NE G
Sbjct: 16560 PLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIG 16619
Query: 1179 EPLDSRD 1185
P + D
Sbjct: 16620 LPAQTAD 16626
Score = 351 bits (901), Expect = 2e-96
Identities = 205/589 (34%), Positives = 309/589 (52%), Gaps = 19/589 (3%)
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKD--GMEVTEEERVSMERGEDQALL 665
VL+ + +TVK G T ++ RGKP P+V W KD ++T RV ++ D +
Sbjct: 11705 VLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKF 11764
Query: 666 TISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAP 725
+++ R D G ++ N GS A ++VLD+P P + ++ +++S + W P
Sbjct: 11765 SLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRN-LKIVDVSSDRCTVCWDPP 11823
Query: 726 KDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVS 785
+D+GG + +I+E+ + W + ++ EG Y FR+ A N G
Sbjct: 11824 EDDGGCEIQNYILEKCETKRMVWSTYSATV-LTPGTTVTRLIEGNEYIFRVRAENKIGTG 11882
Query: 786 DPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGS 845
P E++ V A + PG P+VT V+KE +T+ WN P DGG + GY +E+++K S
Sbjct: 11883 PPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 11942
Query: 846 NLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL 905
WVPVNK I + V LL D EY+FRV A N+ G G+PS+PS VVAKDP++PPG
Sbjct: 11943 TRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGP 12002
Query: 906 VQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMR-----AEDTKEWSKC-TKIPISG 957
+ V D++ SI+L W +P G P GY++EMR A + W +C +
Sbjct: 12003 PTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVR 12062
Query: 958 TCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVR 1017
+TV L E Q+Y FR+ A N+ G+G P EL + ++ P+ DL A ++ ++VR
Sbjct: 12063 KEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVR 12122
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLI--NSTKRSDSGVYRI 1075
AG + + A G P P V W+K G+ R+ + FL+ NST R DSG Y +
Sbjct: 12123 AGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNST-RDDSGKYSL 12181
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIM 1133
L N GE ++VRV D P P ++L++ + + ++W +P + G HYI+
Sbjct: 12182 TLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSW--APPENDGGSQVTHYIVE 12239
Query: 1134 KRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
KR+A TW T V + VT L+PG +YYFRV A NE G P D
Sbjct: 12240 KREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTD 12288
Score = 348 bits (892), Expect = 3e-95
Identities = 218/651 (33%), Positives = 325/651 (49%), Gaps = 40/651 (6%)
Query: 581 GKYTFRAKGTES------EASVFIAD------PPTIDPSVLEALAAHAITVKVGHTAHIK 628
G+Y FR K + A+V D PP+ID + V+ G +I
Sbjct: 9588 GEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSID-------LKEFMEVEEGTNVNIV 9640
Query: 629 VPFRGKPLPKVTWYK------DGME-VTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
+G P P +TW+K D E V + V+ +D L I R D+GL +
Sbjct: 9641 AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTIT 9700
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
N+ G+A+ + L+VL RP PP G ++F +S + + W PKD+GG +T +++E+R
Sbjct: 9701 AVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKR 9760
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
+K+W+ + + K ++ K+ EG Y FRI+A N G+ +PL++E A N
Sbjct: 9761 EANRKTWVHVSS-EPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSV 9819
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQ---- 857
PG +P V+ VT+ ++T+ W P DGG+PV GY +E + S W VN+DPI+
Sbjct: 9820 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 9879
Query: 858 GTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNS 917
G V GL+E ++Y+FRV A+N AG G S+PS A+DP+ PPG V+D + S
Sbjct: 9880 GVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFP-KVTDWTKS 9938
Query: 918 SISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRI 975
S L W P + G +GYI+E + E +EW K + GT V GL E Y FR+
Sbjct: 9939 SADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRV 9998
Query: 976 RAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD 1035
RAVN AG+GEP E+ + +P L A ++ +VV AG + I A SG PPP
Sbjct: 9999 RAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPT 10058
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADF 1095
V W + TI + S +I + +RS GVY +L +NE GE + I V V D
Sbjct: 10059 VTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDV 10118
Query: 1096 PRPPTNLRLFEEVPN-TVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKY 1154
P P L + N + LTW D +Y+I KR++ W V
Sbjct: 10119 PGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA 10178
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINK-----DQIQDLSAK 1200
TV GL+ G+ Y+FR+ A N IG +++ + +I + ++ +DL K
Sbjct: 10179 TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVK 10229
Score = 348 bits (892), Expect = 3e-95
Identities = 210/595 (35%), Positives = 309/595 (51%), Gaps = 17/595 (2%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
IA TI PS+ L + +++ G I++P G+P P ++W KDG + + RV++E
Sbjct: 17807 IAKDLTIQPSL--KLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE 17864
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSC 717
+L I ++D G + N G+AT L + VL++P PP G V F E+S
Sbjct: 17865 ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADF 17924
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
V + W+ P GG ++ +IVE+R +W + + T K++ G YQFRI
Sbjct: 17925 VVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT-IKITKLKTGTEYQFRIF 17983
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYI 837
A N G S PL+++ V P + PG P VT ++K+ + + W+ P DGG ++GY
Sbjct: 17984 AENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYH 18043
Query: 838 VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAK 897
+E+++K S LWV +NK PIQ TK GL E EYEF+V A N G G+PS S VA+
Sbjct: 18044 LEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVAR 18103
Query: 898 DPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPI 955
DP PPG + + + + ++++L W++PA G +GYI+E + W K + +
Sbjct: 18104 DPCDPPGRPEAIVI---TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 18160
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
T +TV GL+E Q+Y FR+ A N AG EP + + A AP L + K +
Sbjct: 18161 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVI 18220
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSG 1071
VV AG + A G P PDV+W KDG T R I + + ++ R+D G
Sbjct: 18221 VVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGG 18280
Query: 1072 VYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGE--A 1128
Y + L N G I V+V D P PP L++ L WN P +Q+ G +
Sbjct: 18281 QYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN--PPLQDGGANIS 18338
Query: 1129 HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
HYII KR+ S +W + V + Y VT LLPG +Y FRV+A N+ G EPL+S
Sbjct: 18339 HYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLES 18393
Score = 345 bits (885), Expect = 2e-94
Identities = 290/986 (29%), Positives = 433/986 (43%), Gaps = 117/986 (11%)
Query: 268 WIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEP 327
WIK T ++ + Q KY IS +N DAG VG+ + ++ +++
Sbjct: 14222 WIKDTTGTALRITQFVVPDLQTKEKYNFRISAIN--DAG-----VGEPAVIPDVEIVER- 14273
Query: 328 LKFLGEMKP---VKVTERQTAVFEIRLS---------KKEPNFVWKFNGKELKRDDKYEI 375
EM P + R+T V LS + P W + LK E
Sbjct: 14274 -----EMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIEN 14328
Query: 376 TVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSR 435
T S L I + D+G+F +TI+ P S NVRV +
Sbjct: 14329 TESFT----LLIIPECNRYDTGKFV-----------MTIEN-PAGKKSGFVNVRVLDTPG 14372
Query: 436 ACLEC---ELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRA--------------ELIIE 478
L ++T VTL W D L+ G++ + KR + +
Sbjct: 14373 PVLNLRPTDITKDSVTLHW--DLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 14430
Query: 479 DAQLSDGGEYTVVAMQD-----GDPTEYYSTAIVTVEERLATVKS-GMSDVHAAT----- 527
LS+G EY M + G+PTE +T V E + S + D+ +T
Sbjct: 14431 VTGLSEGCEYFFRVMAENEYGIGEPTE--TTEPVKASEAPSPPDSLNIMDITKSTVSLAW 14488
Query: 528 -------GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHE 580
GS V+ K W IT + G++ V + G E
Sbjct: 14489 PKPKHDGGSKITGYVIEAQRKGSDQWT----HITTVKGLECVVRNLTE-------GEE-- 14535
Query: 581 GKYTFRAKGTES-------EASVFIADPPTIDPSV-LEALAAHAITVKVGHTAHIKVPFR 632
YTF+ S E+ I T+ P + L + + K G +++P
Sbjct: 14536 --YTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVL 14593
Query: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
G+P P VTW K + + +RV+ E +L I+ CVR DSG L +N G
Sbjct: 14594 GRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDV 14653
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
+ + V D P PP G ++F E+S V W P+++GG P++ ++VE R +W+++
Sbjct: 14654 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELA 14713
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTD 812
+ T + ++ G YQFR+ A N GV + + + A P + PG PQVT
Sbjct: 14714 TTVIRTT-YKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14772
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
VTK+++TI+W+ P DGG+P+LGY VER+++ LW V+K + G GL + Y
Sbjct: 14773 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAY 14832
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGD 930
EFRVIA N AG +PS PS ++A DP+ PPG L++ + +++L W +P G
Sbjct: 14833 EFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNI---TRHTVTLKWAKPEYTGGF 14889
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVEL 989
+ YI+E R W K I +TV GL E Y FR+ A N AG + P E
Sbjct: 14890 KITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEP 14949
Query: 990 DKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE 1049
+ APK + + K ++++AG A + A SG PPP + W KDG +G
Sbjct: 14950 SDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTA 15009
Query: 1050 TI-TKSKNHSQFLIN-STKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFE 1106
+ K + S L+N + R DSG Y + N G A++ +V+V D P PP L + E
Sbjct: 15010 KLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTE 15069
Query: 1107 EVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRK 1164
L+W P + + G HYI+ KR+ S W A V K VT LL G +
Sbjct: 15070 VTSEKCVLSW--FPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNE 15127
Query: 1165 YYFRVVARNEIGDSEPLDSRDTWLIN 1190
Y FRV+A N+ G EPL+S +N
Sbjct: 15128 YIFRVMAVNKYGVGEPLESEPVLAVN 15153
Score = 341 bits (874), Expect = 3e-93
Identities = 190/575 (33%), Positives = 298/575 (51%), Gaps = 8/575 (1%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ +K G ++ G+P P + W KDG E+ ++ ++ + L + R DSG
Sbjct: 14974 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15033
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
L N G A ++ VLDRP PP+G + E++ + W P D+GG + +
Sbjct: 15034 AYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY 15093
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
IV++R + +W + + +VT K+ +G Y FR++AVN GV +PLE+E V A
Sbjct: 15094 IVQKRETSRLAWTNVAS-EVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAV 15152
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
NP PP P+VT +TK+++ + W P DGG+ ++ YIVERR K W+ NK +
Sbjct: 15153 NPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTL 15212
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ V GL E EYEFR++A N AG PS S A D V PG + V D+S
Sbjct: 15213 TDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSR 15272
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCT-KIPISGTCYTVGGLIERQKYFF 973
SSIS+AW +P G +GY++E+ + EW T + T YT+ GL E Q+Y
Sbjct: 15273 SSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKI 15332
Query: 974 RIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
RI A+N G+GEP + +A P+ +L A L+ + +RA L + G P
Sbjct: 15333 RIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPA 15392
Query: 1034 PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVA 1093
P+V W +D + + +I + +++ ++ + R DSG Y + ++N G ++VRV
Sbjct: 15393 PEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVL 15452
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFS 1151
D P PP +L++ E +VTLTW+ P + + G +YI+ KR+++ + T A
Sbjct: 15453 DTPGPPQDLKVKEVTKTSVTLTWD--PPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHK 15510
Query: 1152 NKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDT 1186
+ V L G YYFRV+A NE G P ++ ++
Sbjct: 15511 TSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAES 15545
Score = 340 bits (872), Expect = 5e-93
Identities = 197/589 (33%), Positives = 296/589 (50%), Gaps = 11/589 (1%)
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
PP+++ L+ + VK G T RG P+P W DG E+ +E ++E
Sbjct: 11010 PPSVE---LDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11066
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHM 720
++LTI NC+R D+G + + N GS T +HL+VLD P PP G + L+++ + +
Sbjct: 11067 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 11126
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W+ PKD+GG PV +IVE++ K +W + K T +++G Y FR+ A N
Sbjct: 11127 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK-TKLKIPHLQKGCEYVFRVRAEN 11185
Query: 781 SEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVER 840
GV PL++ A + PP +P VTD+T+ A T++W P DGG+P+ GY +ER
Sbjct: 11186 KIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMER 11245
Query: 841 RKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPV 900
R+ + WV VNK PI K V GL E YEFRV A N AG +PS S + A P+
Sbjct: 11246 REV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPI 11304
Query: 901 KPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGT 958
KPPG + + D S + L W +P G P GY++E + T +W++ K +
Sbjct: 11305 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11364
Query: 959 C-YTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVR 1017
C + V GLIE +Y FRI+A N G GEP EL + V A P+ +L + + VR
Sbjct: 11365 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVR 11424
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
G + I A G P PD+ W K+G + + R + + + I R+D G Y I
Sbjct: 11425 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYII 11484
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
+N G A+ V V D P P NL++ T++W + D ++I+ R
Sbjct: 11485 SAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR 11544
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ W A V + + LL +YYFRV A N++G ++++
Sbjct: 11545 KPNQKGWSIVASDV-TKRLIKANLLANNEYYFRVCAENKVGVGPTIETK 11592
Score = 335 bits (859), Expect = 2e-91
Identities = 196/574 (34%), Positives = 306/574 (53%), Gaps = 14/574 (2%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE--DQALLTISNCVRED 674
+ +K G + IK +G+P+P+VTW+KDG+E+ E+R++ME + L + + R+
Sbjct: 21471 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEI--EKRMNMEITDVLGSTSLFVRDATRDH 21528
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
G+ ++ KN GSA A + + V D P G + F ++G + + W AP ++G P+T
Sbjct: 21529 RGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPIT 21588
Query: 735 QFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF 794
+I+E+R + +W I E + +++ K+ G YQFR+ AVN GV PL+++ V
Sbjct: 21589 HYIIEKRETSRLAWALI-EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVV 21647
Query: 795 AGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPV-NK 853
A P P+ +++T ++T+TW P DGG+ + YI+ERR+K S WV V +K
Sbjct: 21648 AQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISK 21707
Query: 854 DPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSD 913
PI T+ V GL E EYEF V+A N AG G S S + ++PV PPG + V+D
Sbjct: 21708 RPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTD 21767
Query: 914 SSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKY 971
+S +++SL W +P G GYI+EM D +W K T YTV L ++Y
Sbjct: 21768 TSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEY 21827
Query: 972 FFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGS 1031
FR+ A+N AG G+ E+ ++A+ AP+ D+ A K VVRAG ++ + A+ G
Sbjct: 21828 KFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGR 21887
Query: 1032 PPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091
P P +W K R I + + S + + R+D+G Y + ++N G V+
Sbjct: 21888 PTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVK 21947
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA---HYIIMKRDASTATWYTAAER 1148
V D P PP + + + TL W+ +P + DG A HY++ KR+AS +W +E+
Sbjct: 21948 VLDTPGPPGPITFKDVTRGSATLMWD-APLL--DGGARIHHYVVEKREASRRSWQVISEK 22004
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
+ V L G YYFRV A NE G EP +
Sbjct: 22005 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYE 22038
Score = 331 bits (849), Expect = 2e-90
Identities = 210/619 (33%), Positives = 310/619 (50%), Gaps = 26/619 (4%)
Query: 582 KYTFRAKGTESEASVFIADPPTIDPSVLEA---------LAAHAITVKVGHTAHIKVPFR 632
+Y+FR + I+DP + V+ L + TV G + VPF
Sbjct: 15619 EYSFRVSAQNEKG---ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFI 15675
Query: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
G+P P VTW+KD + + + RV+ E E+ +LLTI + RED G ++KL N G A T
Sbjct: 15676 GRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIET 15735
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
L++ VLD+P PP G V+ E++ + + W PK +GG + +IVE+R +W +
Sbjct: 15736 LNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15795
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTD 812
+ T +++ G YQFRI A N G S L +E A P + PG P VT
Sbjct: 15796 ATVARTT-IKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTL 15854
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
+++++ + WN P DGG+ V+GY +ER+++ S LWV +NK PI TK GL E EY
Sbjct: 15855 SSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEY 15914
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGD 930
EFRV A N G G+PS S VA+DP PPG + + V + +S++L W++P G
Sbjct: 15915 EFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIV---TRNSVTLQWKKPTYDGGS 15971
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV-GEPVEL 989
+GYI+E + W K + I T + V GL+E +Y FR+ A N AGV EP E
Sbjct: 15972 KITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSES 16031
Query: 990 DKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK--DGVPTKG 1047
+ A P+ + + K +VV AG + + A G P P + W K +
Sbjct: 16032 TGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTA 16091
Query: 1048 RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEE 1107
R I + + + R DSG Y + +N GE ++V+V D P PP +
Sbjct: 16092 RLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16151
Query: 1108 V-PNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRK 1164
V TL W P +Q+ G +YI+ +R+ S W V + VT LL G +
Sbjct: 16152 VTAEKCTLAW--KPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNE 16209
Query: 1165 YYFRVVARNEIGDSEPLDS 1183
Y FR++A N+ G EPL+S
Sbjct: 16210 YTFRIMAVNKYGVGEPLES 16228
Score = 331 bits (848), Expect = 3e-90
Identities = 261/933 (27%), Positives = 421/933 (45%), Gaps = 67/933 (7%)
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEI 349
G +Y+ + +VN A S S D +++ E +EPL + + + A F +
Sbjct: 19653 GAEYVFRVKSVNKVGASDPSDS-SDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTM 19709
Query: 350 RL---SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+ + PN +W +L+ + T S LT I++A +DSG+++ N+
Sbjct: 19710 TVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLT----IENANRNDSGKYTLTIQNV 19765
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRW---KKDGQLLMHGTK 463
+ A LT+ + N+ V++ +T + L W + DG +
Sbjct: 19766 LSAASLTLVVKVLDTPGPPTNITVQD---------VTKESAVLSWDVPENDGGAPVKNYH 19816
Query: 464 YSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERL---ATVKSGM 520
K+A + + + + Y V +Q+G YY E + A K G+
Sbjct: 19817 IEKREASKKAWVSVTNN--CNRLSYKVTNLQEG--AIYYFRVSGENEFGVGIPAETKEGV 19872
Query: 521 SDVHAATGSPAELCVV-LNDEKVEGVWLK---DGK--------EITDLPGMQIVKQGAVH 568
+ P +L V ++ + V WLK DG E + VK
Sbjct: 19873 K-ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAK 19931
Query: 569 KLIFPSMGPEHEGKYTFRA-----KGTESEASVFIA-------DPPTIDPSVLEALAAHA 616
G +Y FR G + + +PP ID ++ +H
Sbjct: 19932 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEID---MKNFPSHT 19988
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ V+ G + +P GKPLPKVT +DG+ + R + E + + + V D+G
Sbjct: 19989 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20048
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
+ N G+ A +++ VLDRP PP G V +++ V +KW+ PK +GG VT +
Sbjct: 20049 RYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNY 20108
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
I+ +R W ++ + T K+ G+ YQFRI A N G+SD +++ V
Sbjct: 20109 ILLKRETSTAVWTEVSATVAR-TMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVK 20167
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
P PG S P VT+VT+E++T+ W+ P +GG+ V+GY +E + + S LW NK I
Sbjct: 20168 LPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI 20227
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ T V + YEFRV A N AG G+PS PS V+A D +PP +++ ++D S
Sbjct: 20228 RTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPP---RNVRITDISK 20284
Query: 917 SSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+S+SL+W++PA G +GYI+E R W+K + ++ T + + GL + +Y FR
Sbjct: 20285 NSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFR 20344
Query: 975 IRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
+ A N G + P E+ + + P DL + RAGT++ + A SG P
Sbjct: 20345 VFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPA 20404
Query: 1034 PDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091
P + W KD + T + + + + LI R +SG Y + L+N G A I V+
Sbjct: 20405 PTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQ 20464
Query: 1092 VADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF 1150
+ D P PP F+ V +TL W D HYI+ KR+ S W +E +
Sbjct: 20465 ILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLE 20524
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
T T ++ G +Y FRV A N+ G EPL+S
Sbjct: 20525 ECIITTTKIIKGNEYIFRVRAVNKYGIGEPLES 20557
Score = 330 bits (846), Expect = 6e-90
Identities = 206/622 (33%), Positives = 309/622 (49%), Gaps = 19/622 (3%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
+K+G ++ ++ +GK +F K + + PPT+ + L T++V
Sbjct: 10284 LKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELA---PPTLHLDFRDKL-----TIRV 10335
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
G + + GKP PKV+W+KD +V E++R ++ L R DSG +
Sbjct: 10336 GEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVV 10395
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
++N GS ++V+DRP PP G V F E++ + + WK P D+GG +T +I+E++
Sbjct: 10396 VENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKK 10455
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
VGK W+ + K T +K+ EGK Y FRI A N G+SDPL ++ + A +
Sbjct: 10456 EVGKDVWMPVTSASAKTT-CKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRV 10514
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG-TK 860
P QP VT+VTK++ +TWN P DGG P+ YI+E+R+ S W V KDPI TK
Sbjct: 10515 PDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTK 10573
Query: 861 CTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSIS 920
V LLE +YEFRV A N+ G G PS PS V AKDP+ P + D++ +S+
Sbjct: 10574 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10633
Query: 921 LAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPIS--GTCYTVGGLIERQKYFFRIR 976
L W+ P G GYI+E + +EW + P S T Y V GL + Q Y FR+
Sbjct: 10634 LTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVL 10693
Query: 977 AVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
AVN AG +P + + V P+ L A + ++ G L + A G P P V
Sbjct: 10694 AVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKV 10753
Query: 1037 IWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVAD 1094
W+K+ PTK R +T S+ I + D G+Y + ++N G + V V D
Sbjct: 10754 TWKKEDRDAPTKARIDVTPV--GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD 10811
Query: 1095 FPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKY 1154
P PP +L + E ++ LTW D +Y++ +RD ++A W + +
Sbjct: 10812 KPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSH 10871
Query: 1155 TVTGLLPGRKYYFRVVARNEIG 1176
L G +Y FRV A N+ G
Sbjct: 10872 FAKHLNEGNQYLFRVAAENQYG 10893
Score = 326 bits (836), Expect = 8e-89
Identities = 262/890 (29%), Positives = 401/890 (45%), Gaps = 86/890 (9%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQ 411
P VW EL DK + + G L IKDA D G + A G+ A+
Sbjct: 8637 PTKVWTKEEGEL---DKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAAR 8693
Query: 412 LTIDRIPIKFVSNLKNVRVKERSRACLECELTSKD----VT--LRWKKDGQLLMHGTKYS 465
+ + +P V +LK V V R L D +T + +KD + MH +
Sbjct: 8694 VEVFDVPGP-VLDLKPV-VTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQP 8749
Query: 466 MNHEGKRAELIIEDAQLSDGGEYT--VVAMQD---GDPTEYYSTAIV------TVEERLA 514
+ E + ++ L +G EY V+A G P E V T ERL
Sbjct: 8750 IETERSKCDI----TGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLT 8805
Query: 515 TVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPS 574
+ S + P ++G ++ K D P + V + F
Sbjct: 8806 YTERTKSTITLDWKEPRSN----GGSPIQGYIIE--KRRHDKPDFERVNKRLCPTTSFLV 8859
Query: 575 MGPEHEGKYTFRAKGT----ESEAS----VFIAD---PPTIDPSVLEALAAHAITVKVGH 623
+ Y FR K ESE S V I D PPTI + ++ I VK G
Sbjct: 8860 ENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRL--SVRGDTIKVKAGE 8917
Query: 624 TAHIKVPFRGKPLPKVTWYK---------DGMEVTEEERVSMERGEDQALLTISNCVRED 674
HI G P+PK+ W K D +++T+EE + R E + L+I VRED
Sbjct: 8918 PVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEE---VSRSEAKTELSIPKAVRED 8974
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
G + N GS +H+ V DRP PP+ + ++ ++ W AP DNGG +T
Sbjct: 8975 KGTYTVTASNRLGSVFRNVHVEVYDRPSPPRN-LAVTDIKAESCYLTWDAPLDNGGSEIT 9033
Query: 735 QFIVERRAVGKKS--WIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE 792
+++++R +K W ++ + + K+ Y+FR+ AVN G+SD ++++
Sbjct: 9034 HYVIDKRDASRKKAEWEEVTNTAVE-KRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDK 9092
Query: 793 VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW---- 848
V +P PG +P+V TK ++ ++W P +GG+P+ GY +E+R++GS W
Sbjct: 9093 VVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVS 9152
Query: 849 -VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
P+ K ++G + V LLE +Y+FR +A+N AG G PS PS VA DP+ PPG
Sbjct: 9153 RAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPS 9212
Query: 908 DLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTK-IPISGTC-YTVG 963
V D + SSISL W+ PA+ G P GYI+EM+ E T +W + + + TC V
Sbjct: 9213 CPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVP 9272
Query: 964 GLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC 1023
L E +KY FR++AVNEAG EP + + A P+ + + +V +AG+ +
Sbjct: 9273 NLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIR 9332
Query: 1024 IHAAFSGSPPPDVIWQKDGVPTKGRE----------TITKSKNHSQFLINSTKRSDSGVY 1073
I A G P P W+ DG K + + ++N S +I KRS +G Y
Sbjct: 9333 IPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKY 9392
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM 1133
I +N+ G+ + V+V D P PP +L++ + + L+W D D Y+I
Sbjct: 9393 SITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIE 9452
Query: 1134 KRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
KR W S + V LL ++Y+FRV A N G P+++
Sbjct: 9453 KRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVET 9502
Score = 326 bits (836), Expect = 8e-89
Identities = 217/659 (32%), Positives = 323/659 (49%), Gaps = 43/659 (6%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGT---------ESEASVFIADPPTIDPSVLEAL 612
V+ G +L F + +Y FR K E+ +SV I +P + L +
Sbjct: 22096 VEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGI 22155
Query: 613 AAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVR 672
IT K G I VP G+P PKVTW + M + E +RVS+ +D+ LT+ + +R
Sbjct: 22156 TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMR 22215
Query: 673 EDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRP 732
DSG L L+N G T ++ + V+ RP P G +E +S + W PKD GG
Sbjct: 22216 GDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22275
Query: 733 VTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE 792
+T +IVE+R G +W + K T + + Y FR+ + N GVS PLE+
Sbjct: 22276 ITNYIVEKRESGTTAWQLVNS-SVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAP 22334
Query: 793 VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN 852
+ A +P PP ++P+V V+ A++I W P DGG+ ++GY VE++++ + LWV N
Sbjct: 22335 IIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKEN 22394
Query: 853 KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVS 912
K P V GL+E EY+FR A+N AG + S S ++A++PV PG + V+
Sbjct: 22395 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE---VT 22451
Query: 913 DSSNSSISLAWREPA--EGDPPSGYILEMRAED---TKEWSKCTKIPISGTCYTVGGLIE 967
D + S++SL W PA G GYI+E + W KC +S +TV L E
Sbjct: 22452 DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE 22511
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP------AAPKFDLSARLKSHMV-VRAGT 1020
Y FR+ A N AGV + KG + P A PK +L ARL +V +RAG+
Sbjct: 22512 GDTYEFRVLAKNAAGV-----ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGS 22566
Query: 1021 ALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
L + AA G P P +IW K + + ++ + + +I RSDSG Y + ++
Sbjct: 22567 DLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK 22626
Query: 1079 NEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA---HYIIMKR 1135
N G + V+V D P P L + TL W+ QEDG A HYI+ +R
Sbjct: 22627 NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLP---QEDGGAEITHYIVERR 22683
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIG-----DSEPLDSRDTWLI 1189
+ S W + Y VT L+ +Y FRV A N+ G +SEP+ +R+++ I
Sbjct: 22684 ETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTI 22742
Score = 325 bits (833), Expect = 2e-88
Identities = 227/759 (29%), Positives = 365/759 (48%), Gaps = 54/759 (7%)
Query: 587 AKGTESEASVFIADPPTIDPSVLEA-LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+KG+ES V D + L+A L +T++ G + GKP PK+ W K
Sbjct: 22529 SKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22588
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
E+ E+VS++ +A I C R DSG L +KN G+ ++ + VLD P P
Sbjct: 22589 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPC- 22647
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNK 765
G++ ++ + W P+++GG +T +IVERR + +W+ I E + ++ +
Sbjct: 22648 GKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWV-IVEGECPTLSYVVTR 22706
Query: 766 VEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
+ + Y FR+ AVN G P+E+E + A N P P+ KE + I W P
Sbjct: 22707 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 22766
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKD-PIQGTKCTVDGLLEDTEYEFRVIAVNKAGP 884
DGG + Y+V++R+K S W VNKD + T+ V L+E +Y+FRV AVN AG
Sbjct: 22767 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 22826
Query: 885 GQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAE 942
+PS S+ + ++P PG V D++ SISLAW +P G GY+LEM+ +
Sbjct: 22827 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 22886
Query: 943 DTKEWSKC-TKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAA 1001
DT +W + T I T +TV L QKY FR+ AVN G+ E E + +
Sbjct: 22887 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 22946
Query: 1002 PKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
P +L+ LK + +RAG +L + + SG PPP + W K G+ R I ++++S +
Sbjct: 22947 PDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI 23006
Query: 1062 INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
++ R D+G Y I +N+ G+ + V+V D P P ++++ E ++VT+TW P
Sbjct: 23007 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITW-EIPT 23065
Query: 1122 VQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+ DG A +YI+ KR+A+ + T + Y ++GL+ G YYFRV+ N G
Sbjct: 23066 I--DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23123
Query: 1179 EPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLG 1238
EP ++ D L+++ PL P L D T + L
Sbjct: 23124 EPCETSDAVLVSE-------------------------VPLVP-AKLEVVDVTKSTVTLA 23157
Query: 1239 NPRPTVTLYKGDVNIT--------ANSKFWYNSTSGVCTLVIPTCTLKDSGD---YSVLV 1287
+P LY G +T A ++ W + T++ T T + G+ + +
Sbjct: 23158 WEKP---LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRA 23214
Query: 1288 ENELGKDRSSCTLTVYDKDDKSVVASI-TESLQKKSKHL 1325
+NE G T+T D V+ +I ++ +K+ H+
Sbjct: 23215 QNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHV 23253
Score = 325 bits (832), Expect = 2e-88
Identities = 195/607 (32%), Positives = 305/607 (50%), Gaps = 16/607 (2%)
Query: 592 SEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE 651
S A +A I+P V A ++++ V+VG I+VP G+P P +TW KDG+ + +
Sbjct: 16719 SLAVPIVAKDLVIEPDVKPAFSSYS--VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQT 16776
Query: 652 ERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFL 711
R+++ D L+I ++D G + + N G TA++ + LD+P PP+G V+F
Sbjct: 16777 TRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFD 16836
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKA 771
++S + + W P GG +T +IV++R W + + T K++ G
Sbjct: 16837 DVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT-LKVTKLKTGTE 16895
Query: 772 YQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA 831
YQFRI A N G S LE++ + A P + PG P T ++K+++ I W+ P +GG+
Sbjct: 16896 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 16955
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
PV+GY +ER+++ S LW VNK I T+ L E EYEFRV A N G G+ S S
Sbjct: 16956 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 17015
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSK 949
VA+DP PPG + + V + I+L W +P G +GYI+E R W K
Sbjct: 17016 ECYVARDPCDPPGTPEPIMV---KRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMK 17072
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSA 1008
+ + T +TV GL E Q+Y FR+ A N AG + +P + + A P+ +
Sbjct: 17073 ASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDP 17132
Query: 1009 RLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTK 1066
+ + +VV AG + A G P P + W + + R I + + ++
Sbjct: 17133 KFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAI 17192
Query: 1067 RSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQED 1125
R D G Y + N G + ++V+V D P PP +++ +LTW SP +Q+
Sbjct: 17193 RIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW--SPPLQDG 17250
Query: 1126 GE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
G +HY++ KR+ S W A V +N VT LL G +Y FR++A N+ G EPL+S
Sbjct: 17251 GSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLES 17310
Query: 1184 RDTWLIN 1190
+ N
Sbjct: 17311 APVLMKN 17317
Score = 318 bits (816), Expect = 2e-86
Identities = 196/641 (30%), Positives = 304/641 (47%), Gaps = 25/641 (3%)
Query: 557 PGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEA--------SVFIADPPTIDPSV 608
P + + V L G + KY FR + V+ A + P +
Sbjct: 12346 PADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI 12405
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L IT+K G I+ GKP P W K EV +++ + + ++L I
Sbjct: 12406 L---MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 12462
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
+ R+DSG L +N G+ T + + V+D P PPQ + ++ + W P ++
Sbjct: 12463 DVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLED 12522
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG +T +IVE+ V + W+ K T+ K+ G+ Y FR+ A N G+S+PL
Sbjct: 12523 GGSNITNYIVEKCDVSRGDWVTALASVTK-TSCRVGKLIPGQEYIFRVRAENRFGISEPL 12581
Query: 789 ETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW 848
+ ++ A P P +VT V K+ + + W+ P DGG+P++GY++ER+++ S LW
Sbjct: 12582 TSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLW 12641
Query: 849 VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQD 908
V N ++ T+ GL+E EY FR+ A+NKAG PS P+ V A+ PV PPG +
Sbjct: 12642 VKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPE- 12700
Query: 909 LHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIP--ISGTCYTVGG 964
V D + S++SL W P G GY +E +W +C P I YT G
Sbjct: 12701 --VIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATG 12758
Query: 965 LIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCI 1024
L E+ +Y FR A + P E V + P+ DLS +KS + V+AGT +C+
Sbjct: 12759 LEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 12818
Query: 1025 HAAFSGSPPPDVIWQKDGVPTKGRETI--TKSKNHSQFLINSTKRSDSGVYRILLQNEFG 1082
A G P P V W+KDG K E I +N + S R DSG Y I +N G
Sbjct: 12819 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 12878
Query: 1083 EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTA 1140
I ++V D P PP ++++ + + L+W P +++ G +YI+ KR+ S
Sbjct: 12879 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSW--EPPLEDGGSEITNYIVDKRETSRP 12936
Query: 1141 TWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPL 1181
W + V +V L+ G +Y FR+ A N+ G +P+
Sbjct: 12937 NWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPV 12977
Score = 317 bits (812), Expect = 5e-86
Identities = 193/605 (31%), Positives = 291/605 (48%), Gaps = 26/605 (4%)
Query: 598 IADPPTIDPSVLEALA-----------AHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
++DP TI P ++ L +TV++GH H+++P++GKP P ++W KDG+
Sbjct: 21046 LSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGL 21105
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
+ E E V + E++ L+I N +E G + L N + + L P P+G
Sbjct: 21106 PLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKG 21165
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
+ F E+ V + W P+DNGG +T + +E+R + +W + + T N V
Sbjct: 21166 PIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLV 21225
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
++ + YQFR+ A N GVS PL + + A + PG +P + +VT + +++TW+AP
Sbjct: 21226 KDAE-YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPV 21284
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQ 886
DGG+ V G+ VE++++ S LW VN PI G + GL+E +Y+FRV A N AG
Sbjct: 21285 YDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSS 21344
Query: 887 PSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDT 944
PS PS +A PV PPG + D + +I+L W P G GY +E R +
Sbjct: 21345 PSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKR-QGN 21400
Query: 945 KEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG-VRAMPPPAAPK 1003
+ W +C +S YTV GL +Y FRI A N G P G + P
Sbjct: 21401 ERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPI 21460
Query: 1004 FDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRET--ITKSKNHSQFL 1061
+ +++++G +L I A G P P V W KDGV + R IT +
Sbjct: 21461 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 21520
Query: 1062 INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+ R GVY + +N G A+ +I V+V D P F + W +P
Sbjct: 21521 VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAP- 21579
Query: 1122 VQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
DG A HYII KR+ S W ++ + YT L+ G +Y FRV A N+ G
Sbjct: 21580 -LNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 21638
Query: 1179 EPLDS 1183
PLDS
Sbjct: 21639 RPLDS 21643
Score = 313 bits (801), Expect = 9e-85
Identities = 262/892 (29%), Positives = 399/892 (44%), Gaps = 90/892 (10%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTID 415
P W +GKE+K D+ +T+ D ++ L++ + +D+G ++ N + A +I+
Sbjct: 7919 PTVSWHKDGKEVKASDR--LTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 7976
Query: 416 RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAEL 475
I K+++ + +++ C+LT + DG + G+R +
Sbjct: 7977 VKVIGLPGPCKDIKASDITKS--SCKLTWEPPEF----DGGTPILHYVLERREAGRRTYI 8030
Query: 476 IIEDAQ---------LSDGGEY--TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524
+ + L GEY V A+ EY + + DV
Sbjct: 8031 PVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8090
Query: 525 AATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVK---------QGAVHKLIFPSM 575
+ + + +G G +I +I K + V L + +
Sbjct: 8091 VHNPTAEAMTITWKPPLYDG-----GSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAK 8145
Query: 576 GPEHEGKYTFRAKGTESEASVFI---ADPPT--IDP-SVLEALAAHAITVKVGHTAHIKV 629
G E +Y FR + E+ A + A PPT +DP + + ++ VK G +
Sbjct: 8146 GLEEGKEYQFRVRA-ENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDA 8204
Query: 630 PFRGKPLPKVTWYKDGM--------------------EVTEEE--------RVSME---R 658
G P P +TW KD EV EEE R+S++ +
Sbjct: 8205 SISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKK 8264
Query: 659 GEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCV 718
GE Q L + + +R D GL ++K++NDHG A A +SVLD P PP V F ++ + V
Sbjct: 8265 GESQ--LRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFV-FEDIRKTSV 8321
Query: 719 HMKWKAPKDNGGRPVTQFIVERRAVGK--KSWIKIGEVDGKVTNFSTNKVEEGKAYQFRI 776
KW+ P D+GG + + +E++ K WI + + +S K+ EGK Y FR+
Sbjct: 8322 LCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTL-RHCKYSVTKLIEGKEYLFRV 8380
Query: 777 LAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGY 836
A N G P ++ + A +P PP +P V DVT ++ + WN P +D G+P+LGY
Sbjct: 8381 RAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEP-KDNGSPILGY 8439
Query: 837 IVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVA 896
+E+R+ S W VNK + K VDGLLE Y FRV A N AGPG+ S PS A
Sbjct: 8440 WLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTA 8499
Query: 897 KDPVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIP 954
DP+ PPG V+D+S+++I L W PA G GY ++ + T EWS+CT+
Sbjct: 8500 HDPISPPG-PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM 8558
Query: 955 ISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
I YTV + E Y R+ AVN AG G P E + V P P +L +K +
Sbjct: 8559 IKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE-TQPVTVAEPQEPPAVELDVSVKGGI 8617
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
+ AG L I A +G P P +W K +G K R I S+ +I R D G Y
Sbjct: 8618 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 8677
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---Y 1130
I N G V V D P P +L+ L W+ D ++DG + +
Sbjct: 8678 VITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWS---DPEDDGGSEITGF 8734
Query: 1131 IIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
II ++DA TW E S K +TGLL G++Y FRV+A+N+ G P++
Sbjct: 8735 IIERKDAKMHTWRQPIETERS-KCDITGLLEGQEYKFRVIAKNKFGCGPPVE 8785
Score = 308 bits (790), Expect = 2e-83
Identities = 202/595 (33%), Positives = 288/595 (48%), Gaps = 19/595 (3%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
IA I PSV L H VK I VPF+G+P V W KDG + E RV++
Sbjct: 18890 IARDIEIKPSV--ELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVS 18947
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSC 717
+ L+I +ED G L + N GS T + + VLDRP PP G + E+S
Sbjct: 18948 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDS 19006
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
+ + W P+ +GG ++ +IVE++ +W + + + T+ ++ G YQFR+
Sbjct: 19007 ITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVAR-TSIKIVRLTTGSEYQFRVC 19065
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYI 837
A N G S E+ V A P PPG P+V TK + +TW P DGG+ V+GY
Sbjct: 19066 AENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYH 19125
Query: 838 VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAK 897
+E +++ S LW NK I T+ V GL E YE+RV A N AG G+ S V A+
Sbjct: 19126 LEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPAR 19185
Query: 898 DPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPPSGYILEMRAEDTKEWSKCTKIPI 955
DP PPG + V++ + S+SL W +P G +GYI+E R W KC I
Sbjct: 19186 DPCDPPGQPE---VTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNI 19242
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEA-GVGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
T + V L E Q+Y FR+ A N A V EP E + P+ + + + +
Sbjct: 19243 QETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVI 19302
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGV 1072
VV+AG L I+A +G P P + W KDG + + R I + NH+ + R D+G
Sbjct: 19303 VVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQ 19362
Query: 1073 YRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGEA--- 1128
Y + L+N G ++ +V D P PP L + +L+W QEDG A
Sbjct: 19363 YVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRP---QEDGGADID 19419
Query: 1129 HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+YI+ KR+ S W + VT LL G +Y FRV N+ G EPL+S
Sbjct: 19420 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLES 19474
Score = 293 bits (751), Expect = 6e-79
Identities = 187/608 (30%), Positives = 301/608 (49%), Gaps = 25/608 (4%)
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
++ TE +V + P I L+ +TVK G + GKP PK+TW K M
Sbjct: 7176 SRPTEEIQAVDTQEAPEI---FLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM 7232
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
+ +++R+++E ++ +TI + R D+G +++ N G ATA + ++VLD+P PP
Sbjct: 7233 ILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAA 7292
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
+ +++ + W P+D+GG +T ++VERRA + W K+ K TNF K+
Sbjct: 7293 -FDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTV-KDTNFKATKL 7350
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
K Y FR+ A N GV +P++ + A +PPG ++ + +D+TK+AVT+TW P
Sbjct: 7351 IPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPD 7410
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQ 886
DGG+P+ GY VER ++ WV NK P++ T V GL +Y FRV+A N AGPG+
Sbjct: 7411 DDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGK 7470
Query: 887 PSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDT 944
PS + ++ KDP+ PP V D +S+ L W +P G Y++EM T
Sbjct: 7471 PSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGT 7530
Query: 945 KEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV---RAMPPPAA 1001
EW + + + T + + GL+E Q+Y FR+RAVN+AG EP E V + PP+
Sbjct: 7531 DEWVRVAE-GVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSP 7589
Query: 1002 PKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
P++ + + A + GSP + I +K V KG +T+ + ++
Sbjct: 7590 PRWLEVINITKN---TADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7646
Query: 1062 INSTKRSDSGVYRILLQNEFGEARY---DIHVRVAD---FPRPPTNLRLFEEVPNTVTLT 1115
+ V+R+ +N G++ Y + V D P PP L + + V L
Sbjct: 7647 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLK 7706
Query: 1116 WNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSN-KYTVTGLLPGRKYYFRVVAR 1172
W P + G Y+I K++ W A + + + VT ++ G + F+V A
Sbjct: 7707 W--EPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAE 7764
Query: 1173 NEIGDSEP 1180
NE G P
Sbjct: 7765 NEAGVGHP 7772
Score = 285 bits (729), Expect = 2e-76
Identities = 315/1307 (24%), Positives = 527/1307 (40%), Gaps = 123/1307 (9%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
EF+ KPQ + EG+KA F + + P + WKR+ ++ K + K+ VL +
Sbjct: 6056 EFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKT-LESGDKYDVIADGKKRVLVV 6113
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTV-----------SLLVTEGQEKM-------DFKKM 169
+ T D Y + A A TV V E QE + + K
Sbjct: 6114 KDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKA 6173
Query: 170 LKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKV 229
R A K + +K+++ L ++ T+ RG K V
Sbjct: 6174 KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVK-SAANLIV 6232
Query: 230 EVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPL----RIQYSLGKYD 285
E E +RI++PL+D ET +V F C ++ NV + W K E + R+ Y + KY
Sbjct: 6233 EEEDLRIVEPLKDIETMEKKSVTFWC--KVNRLNVTLKWTKNGEEVPFDNRVSYRVDKY- 6289
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
K+ML I + D G Y ++ G + AEL +++ P +F+ ++ VTE A
Sbjct: 6290 ------KHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDA 6343
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
VF +LS+++ N W NG+E+K KY+ +DG H L IKD RL D E++ +
Sbjct: 6344 VFSCQLSREKANVKWYRNGREIKEGKKYKF--EKDGSIHRLIIKDCRLDDECEYACGVED 6401
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
+A+L ++ IP++ + +++ + EL V ++W ++ +++ G K+
Sbjct: 6402 RKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQ 6461
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
M EGK L I D + D GEY +A +D + A +K+ D+
Sbjct: 6462 MMSEGKIHRLQICDIKPRDQGEYRFIA-KDKEARAKLELAAAP------KIKTADQDLVV 6514
Query: 526 ATGSPAELCVVLND-EKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
G P + V + K E W K+ + ++ + + +++ G + K
Sbjct: 6515 DVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT-IDTTAEQTSFRILEAKKGDKGRYKIV 6573
Query: 585 FRAKGTESEA----SVFIADPPTIDPSVLEAL-----AAHAITVKVGHTAHIKVPFRGKP 635
+ K ++E V P + V E A + G + I +
Sbjct: 6574 LQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRD 6633
Query: 636 LPKVTWY--KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
+ + TW D E E +++G + L +S R +G ++ D+ +
Sbjct: 6634 IKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE---PVETDNPVEARSK 6690
Query: 694 HLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGE 753
+ D P PP V +++ V + W+ P+ +GG +T +++E R W
Sbjct: 6691 Y----DVPGPPLN-VTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMT 6745
Query: 754 VDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP-LETEEVFAGNPIEPPGFASQPQVTD 812
V + + + V EG+ Y FR+ A N GV P T V +PIE P +D
Sbjct: 6746 VRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSD 6805
Query: 813 VTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY 872
T+ +V + W P +DGG+P+LGYI+ER ++G + W+ N + V GL + +Y
Sbjct: 6806 QTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKY 6865
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPP 932
+RV A NKAG PS + A D P + DL + + + P P
Sbjct: 6866 LYRVSAENKAGVSDPSEILGPLTADDAFVEPTM--DL---SAFKDGLEVIVPNPITILVP 6920
Query: 933 S-GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDK 991
S GY T W K+ +G +R K + A E + DK
Sbjct: 6921 STGY-----PRPTATWCFGDKVLETG---------DRVK-MKTLSAYAELVISPSERSDK 6965
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAG----------TALCIHAAFS------GSPPPD 1035
G+ + K +S + +++ R T +H + GSP
Sbjct: 6966 GIYTLKLENRVK-TISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTG 7024
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGE---ARYDIHVRV 1092
+ +K V K + +F + + ++++ +N+ G A D V +
Sbjct: 7025 YVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNM 7084
Query: 1093 ---ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERV 1149
A P PP N++ + N++ LTW+ + YI+ + + W E V
Sbjct: 7085 STPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPV 7144
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
K VTGL G+ Y +RV A N G S+P SR T ++IQ + + P D
Sbjct: 7145 AETKMEVTGLEEGKWYAYRVKALNRQGASKP--SRPT-----EEIQAVDTQEAPEIFLD- 7196
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
V L TV G + G P P +T K D+ + + + + T
Sbjct: 7197 ------VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST 7250
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
+ I D+G Y + N G+ + + V DK IT+
Sbjct: 7251 VTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITD 7297
Score = 273 bits (699), Expect = 6e-73
Identities = 160/493 (32%), Positives = 252/493 (51%), Gaps = 15/493 (3%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ +E + ++ + +KW P+ +GG P+T +IVE+R V +K W + + K T
Sbjct: 7587 PSPPRW-LEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV-DTTVKDTK 7644
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVT 819
+ + EG Y FR+ A N+ G SD E E+ V A + PG V DVTK V
Sbjct: 7645 CTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVD 7704
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAV 879
+ W P DGG P+ Y++E++++ WV K V ++E TE +F+V A
Sbjct: 7705 LKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAE 7764
Query: 880 NKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYIL 937
N+AG G PS P+ + +DP PP DLHV+D+ I++AW+ P + G P GY +
Sbjct: 7765 NEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHV 7824
Query: 938 EMRAEDTKEWSKCTKIPISGTCYTV-GGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
EM T++W + PI + V G++ ++Y R+RAVN GV EP E+ + V A
Sbjct: 7825 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 7884
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKN 1056
P P DL ++V G L I F P P V W KDG K + +T +
Sbjct: 7885 DPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKND 7941
Query: 1057 H--SQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
H + + + R+D+G+Y I L+N+ G A I+V+V P P +++ + ++ L
Sbjct: 7942 HISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKL 8001
Query: 1115 TWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVAR 1172
TW P + G HY++ +R+A T+ +TV L+P +Y+FRV A
Sbjct: 8002 TW--EPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 8059
Query: 1173 NEIGDSEPLDSRD 1185
N++G E ++ ++
Sbjct: 8060 NKVGGGEYIELKN 8072
Score = 255 bits (652), Expect = 2e-67
Identities = 168/569 (29%), Positives = 270/569 (47%), Gaps = 36/569 (6%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
I V+ G + +P +GKP P W K+G ++++ R + E L I R DSG
Sbjct: 23649 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK--RAMIATSETHTELVIKEADRGDSG 23706
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
L L+N G + + V+ P P+G +E+ ++ V + W+ P D+GG + +
Sbjct: 23707 TYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGY 23766
Query: 737 IVERRAVGKKSWIKIGEVDGKV--TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF 794
I+ERR V K +W I D +V T+ ++E Y FR+ A N G+S PL++EE
Sbjct: 23767 ILERREVPKAAWYTI---DSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 23823
Query: 795 AG----NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP 850
NP EPP ++ P+V DVTK +V+++W+ P DGG+ V GY +ER++ ++ WV
Sbjct: 23824 TPKTPLNPPEPP--SNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 23881
Query: 851 VNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLH 910
NK I T TV GL+ D EY+FR+IA N G + S S VV KDP P +L
Sbjct: 23882 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 23941
Query: 911 VSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ S S++L W +P G GY +E R W K K I +T+GGL+E
Sbjct: 23942 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24001
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRA-MPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
+Y FR+ A NE G+ P ++ + AP + +K + + G A +
Sbjct: 24002 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAP--GIRKEMKD-VTTKLGEAAQLSCQ 24058
Query: 1028 FSGSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEA 1084
G P PD+ W + G + ++ + + + H+ + + ++ D GVY + NE GE
Sbjct: 24059 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT-LTVMTEEQEDEGVYTCIATNEVGEV 24117
Query: 1085 RYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
+ + P+ L E+ V T H + + R TW+
Sbjct: 24118 ETSSKLLLQATPQFHPGYPLKEKYYGAVGSTL----------RLHVMYIGRPVPAMTWF- 24166
Query: 1145 AAERVFSNKYTVTGLLPGRKYYFRVVARN 1173
+++ N +T + ++Y +V +N
Sbjct: 24167 HGQKLLQNSENIT--IENTEHYTHLVMKN 24193
Score = 252 bits (643), Expect = 2e-66
Identities = 205/799 (25%), Positives = 359/799 (44%), Gaps = 50/799 (6%)
Query: 438 LECELTSKD-VTLRWKK---DG--QLLMHGTKYSMNHEG---KRAELIIEDAQLSDGG-- 486
LE SKD VTL+W+K DG ++L + +Y + + K + I+D Q + GG
Sbjct: 23940 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 23999
Query: 487 -----EYTVVAMQDGDPTEYYSTAIVTVEERLAT-----VKSGMSDVHAATGSPAEL-CV 535
E+ V A + + TA+ +++ +L + ++ M DV G A+L C
Sbjct: 24000 EATEYEFRVFAENETGLSRPRRTAM-SIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24058
Query: 536 VLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKG----TE 591
++ + W + GKE+ ++ G H L + E EG YT A E
Sbjct: 24059 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24118
Query: 592 SEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE 651
+ + + + P P + VG T + V + G+P+P +TW+ +
Sbjct: 24119 TSSKLLLQATPQFHPGYPLKEKYYGA---VGSTLRLHVMYIGRPVPAMTWFHGQKLLQNS 24175
Query: 652 ERVSMERGEDQALLTISNCVRED-SGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEF 710
E +++E E L + N R+ +G ++L N G+ A L + + D+P P G +
Sbjct: 24176 ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVI 24235
Query: 711 LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGK 770
L + + WK P D+GG +T ++VE+ + + ++ VT + E
Sbjct: 24236 EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 24295
Query: 771 AYQFRILAVNSEGVSDPLETEEV-FAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDG 829
Y FR+ A N+ G+SDPLE V +P E PG +P +T VTK++ + W P DG
Sbjct: 24296 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDG 24355
Query: 830 GAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSV 889
GA + Y +E+R+K N W+ V + I+ T +V L+E EYEFRV N G + S
Sbjct: 24356 GAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSE 24415
Query: 890 PSSSVVAKD--PVKPPGLVQDL-HVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKE 946
S + K P++ P ++L +++ S+ +L + P + + + E +
Sbjct: 24416 ISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK-EIIAD 24474
Query: 947 WSKCTKIPISGTCY--TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKF 1004
K G + + + + +++RA N+ G G ++ K
Sbjct: 24475 GLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGG------SVSGTASLEVEVPAKI 24528
Query: 1005 DLSARLKSHMVVRA--GTALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQF 1060
L L+ V A G + I FSG P P + WQK D + G + +++ +
Sbjct: 24529 HLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSL 24588
Query: 1061 LI-NSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHS 1119
+ N +R D+G Y + +N FG + + + VAD P PP +++ + ++V LTW
Sbjct: 24589 VFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24648
Query: 1120 PDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
+YI+ ++ A+TA + + +YTV L Y FRV+A N+ G S+
Sbjct: 24649 ASDGGSKITNYIV-EKCATTAERWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSK 24707
Query: 1180 PLDSRDTWLINKDQIQDLS 1198
P + + + +D+ + ++
Sbjct: 24708 PSEPSEPTITKEDKTRAMN 24726
Score = 243 bits (621), Expect = 7e-64
Identities = 306/1277 (23%), Positives = 500/1277 (39%), Gaps = 142/1277 (11%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARV-QGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
EF + + T EG AV V + NAK + W + +G I +S K + + L
Sbjct: 5789 EFTKPLEDQTVEEGATAVLECEVSRENAK--VKWFK-NGTEILKSKKYEIVADGRVRKLV 5845
Query: 127 LEPLTSDDSDNYKCIASN-----------DHADAIYTVSLLVTEGQEKMDFK-------- 167
+ T +D Y C A + H + + ++ L +E F+
Sbjct: 5846 IHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENA 5905
Query: 168 --KMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEM 225
K K A KK ++ + +++K D + E G+L L+E
Sbjct: 5906 KVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEE- 5964
Query: 226 KKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYD 285
EA+ K L + E T+ C E+ P ++IW KG E + G+Y+
Sbjct: 5965 ------EAV-FTKNLANIEVSETDTIKLVC--EVSKPGAEVIWYKGDEEI---IETGRYE 6012
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
+ G K +LVI N ++ DAG Y+ + R ++ V + +F+ + + +++ E + A
Sbjct: 6013 ILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKA 6072
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
F +SK+ WK + K L+ DKY++ DG L +KDA L D G + G
Sbjct: 6073 EFVCSISKESFPVQWKRDDKTLESGDKYDVIA--DGKKRVLVVKDATLQDMGTYVVMVGA 6130
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
A LT+ ++ V LK+ RVKE+ CE+ ++ +W ++ + + +KY
Sbjct: 6131 ARAAAHLTVIE-KLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYI 6189
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ + L I DA L D Y V ++ + S A + VEE + + D+
Sbjct: 6190 ILQKDLVYTLRIRDAHLDDQANYNV-SLTNHRGENVKSAANLIVEEEDLRIVEPLKDIET 6248
Query: 526 ATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
+N V W K+G+E+ + H L G EG+Y
Sbjct: 6249 MEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIV 6308
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
A +S A + I + PT +E L +T ++ + V WY++G
Sbjct: 6309 TAGQDKSVAELLIIEAPT---EFVEHLEDQTVTEFDDAVFSCQL---SREKANVKWYRNG 6362
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
E+ E ++ E+ L I +C +D +++ A + ++ +PPQ
Sbjct: 6363 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQ 6422
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAV--GKKSWIKIGEVDGKVTNFST 763
+ LE G+ V + KD + Q++ V G K + +GK+
Sbjct: 6423 ---DILEAPGADVVFLAELNKD---KVEVQWLRNNMVVVQGDKHQMMS---EGKIHRLQI 6473
Query: 764 NKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWN 823
++ ++R +A + E + E+ A I+ A Q V DV K +
Sbjct: 6474 CDIKPRDQGEYRFIAKDKEARAKL----ELAAAPKIKT---ADQDLVVDVGKPLTMVV-- 6524
Query: 824 APTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAG 883
P Y K W N +P+ TK T+D E T FR++ K
Sbjct: 6525 --------PYDAY-----PKAEAEWFKEN-EPLS-TK-TIDTTAEQTS--FRILEAKKGD 6566
Query: 884 PGQPSV-------PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSG 934
G+ + + + + PG V++L V+++ + +SLAW EP G G
Sbjct: 6567 KGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIG 6626
Query: 935 YILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQ-KYFFRIRAVNEAGVGEPVELDKGV 993
Y++E R K W T S +TV GL + +Y FR+ A N G GEPVE D V
Sbjct: 6627 YVVERRDIKRKTWVLATDRAESCE-FTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPV 6685
Query: 994 RAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD----------VIWQKDGV 1043
A P L+ + V R G +L PP+ VI +D
Sbjct: 6686 EARSKYDVPGPPLNVTITD--VNRFGVSLTWE-------PPEYDGGAEITNYVIELRDKT 6736
Query: 1044 PTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDI---HVRVAD---FPR 1097
+ +T + +R+ QN G + V+VAD P
Sbjct: 6737 SIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPS 6796
Query: 1098 PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSN-KY 1154
PP NL ++ ++V L W P +++ G YII + + W ++ Y
Sbjct: 6797 PPVNLTSSDQTQSSVQLKWE--PPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTY 6854
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPR 1214
VTGL G KY +RV A N+ G S+P + L D + + L ++ P
Sbjct: 6855 KVTGLEKGNKYLYRVSAENKAGVSDPSEILGP-LTADDAFVEPTMDLSAFKDGLEVIVPN 6913
Query: 1215 FVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPT 1274
+T L P T G PRPT T GD + + + S LVI
Sbjct: 6914 PITILVPST--------------GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISP 6959
Query: 1275 CTLKDSGDYSVLVENEL 1291
D G Y++ +EN +
Sbjct: 6960 SERSDKGIYTLKLENRV 6976
Score = 208 bits (529), Expect = 3e-53
Identities = 167/633 (26%), Positives = 273/633 (43%), Gaps = 66/633 (10%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
D P PP R+E +++ V + W P D+GG P+T + VER W++ ++ K
Sbjct: 7384 DPPGPPT-RLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD 7442
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVTKEA 817
T + + K Y+FR+LA N G P + TE + +PI+PP +P V DV K +
Sbjct: 7443 TTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTS 7502
Query: 818 VTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVI 877
V + W P DGGA + Y++E K G++ WV V + + T+ + GL+E EY FRV
Sbjct: 7503 VRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVR 7561
Query: 878 AVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGY 935
AVNKAG +PS PS V+ ++ + PP + L V + + ++ L W P + G P + Y
Sbjct: 7562 AVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNY 7621
Query: 936 ILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRA 995
I+E R K W + + T TV L E Y FR+ A N G + E++ V A
Sbjct: 7622 IVEKRDVRRKGW-QTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLA 7680
Query: 996 M-------PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPD---------VIWQ 1039
PP A D++ R H PP + VI +
Sbjct: 7681 KDTFTTPGPPYALAVVDVTKR---------------HVDLKWEPPKNDGGRPIQRYVIEK 7725
Query: 1040 KDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADF---- 1095
K+ + T+ + + F + +++ +NE G +
Sbjct: 7726 KERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPT 7785
Query: 1096 --PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFS 1151
P PP +L + + + + W P + G Y + T W R
Sbjct: 7786 SPPSPPLDLHVTDAGRKHIAIAWK--PPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 7843
Query: 1152 N-KYTVT-GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
+ K+ V G++P ++Y RV A N IG SEP + + ++ KD + L+ ++
Sbjct: 7844 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISEN-VVAKDPDCKPTIDLETHDI--- 7899
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
V+ G+ ++ F P PTV+ +K + A+ + +
Sbjct: 7900 -------------IVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 7946
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L +P D+G Y++ +EN+LG +S + V
Sbjct: 7947 LEVPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 208 bits (529), Expect = 3e-53
Identities = 143/432 (33%), Positives = 213/432 (49%), Gaps = 26/432 (6%)
Query: 762 STNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTIT 821
+ N+ + GK + + NS G V ++ PG +V +VTK +VT+T
Sbjct: 15423 NVNRFDSGK---YILTVENSSGSKSAFVNVRV-----LDTPGPPQDLKVKEVTKTSVTLT 15474
Query: 822 WNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNK 881
W+ P DGG+ + YIVE+R+ + V + T VD L E Y FRV+A N+
Sbjct: 15475 WDPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENE 15533
Query: 882 AGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEM 939
G G P+ + SV A + PPG + + D + +S+SL+W +P G GYI+EM
Sbjct: 15534 YGIGLPAETAESVKASERPLPPGKIT---LMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15590
Query: 940 RAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP 999
+ + + +W+ C + ++ T+ GLI+ ++Y FR+ A NE G+ +P +L V A
Sbjct: 15591 QTKGSDKWATCATVKVTEA--TITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV 15648
Query: 1000 AAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKG--RETITKSKNH 1057
P F L L + V AG L + F G P P V W KD VP K R ++N+
Sbjct: 15649 IPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN 15705
Query: 1058 SQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN-LRLFEEVPNTVTLTW 1116
S I R D G Y + L N GEA ++V V D P PPT +++ E +++TL+W
Sbjct: 15706 SLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSW 15765
Query: 1117 NHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNE 1174
P + G + +YI+ KRD ST TW + V L G +Y FR+ A N
Sbjct: 15766 G--PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENR 15823
Query: 1175 IGDSEPLDSRDT 1186
G S L+S T
Sbjct: 15824 YGKSTYLNSEPT 15835
Score = 204 bits (518), Expect = 6e-52
Identities = 122/391 (31%), Positives = 190/391 (48%), Gaps = 6/391 (1%)
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N I P + + D+TK++V +TW P DGG+P+ GY+VE+R+ W V D +
Sbjct: 6986 NVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDFV 7044
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ TV L++ EY F+V A NK GPG+P+ V P P +++ D +
Sbjct: 7045 TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTA 7104
Query: 917 SSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+SI L W P G GYI+E + +W C + P++ T V GL E + Y +R
Sbjct: 7105 NSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGE-PVAETKMEVTGLEEGKWYAYR 7163
Query: 975 IRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPP 1034
++A+N G +P + ++A+ AP+ L +L + + V+AGT + + A +G P P
Sbjct: 7164 VKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP 7223
Query: 1035 DVIWQKDGVPTKG--RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV 1092
+ W K + K R TI S I +KRSD+G Y I N G A + V V
Sbjct: 7224 KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283
Query: 1093 ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSN 1152
D P PP + + + LTWN D +Y++ +R + W+ + V
Sbjct: 7284 LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDT 7343
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ T L+P ++Y FRV A N G EP+ +
Sbjct: 7344 NFKATKLIPNKEYIFRVAAENMYGVGEPVQA 7374
Score = 201 bits (512), Expect = 3e-51
Identities = 144/532 (27%), Positives = 249/532 (46%), Gaps = 31/532 (5%)
Query: 168 KMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKK 227
K K P K + V+ K +L + D + +T G L E K
Sbjct: 2780 KWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGE------YTAVVGQL----ECKA 2829
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K+ VE + I K +++ E T F+C E+ NV +W+K + + K+ +
Sbjct: 2830 KLFVETLHITKTMKNIEVPETKTASFEC--EVSHFNVPSMWLKNGVEIEMSE---KFKIV 2884
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G + L+I N + D+ Y+ G+ ++SA LTV P+ +K + E+ T F
Sbjct: 2885 VQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVT--PIMITSMLKDINAEEKDTITF 2942
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E+ ++ + ++ W NG E+K DK ++ + LTH+L I++ D+ +++ AG
Sbjct: 2943 EVTVNYEGISYKWLKNGVEIKSTDKCQMRTKK--LTHSLNIRNVHFGDAADYTFVAGKAT 3000
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A L ++ I+F ++K+++V E+ RA ECE++ D+T++W KD Q L + +
Sbjct: 3001 STATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQ 3060
Query: 468 HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT 527
E L+I ++SD G+YTVVA + STA + VE R ++S +V
Sbjct: 3061 KEKYVHRLLIPSTRMSDAGKYTVVAGGN------VSTAKLFVEGRDVRIRSIKKEVQVIE 3114
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEIT--DLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A + +N++ V+ W KDG EI + V + +H++ G+YTF
Sbjct: 3115 KQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTF 3174
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
A S ++++ P P VL+ L +TV+ G A G+P PK++WYK+
Sbjct: 3175 VAGRNRSSVTLYVNAPE--PPQVLQEL--QPVTVQSGKPARFCAVISGRPQPKISWYKEE 3230
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
++ + + L + ED+ + + KND+G AT + LSV
Sbjct: 3231 QLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 201 bits (512), Expect = 3e-51
Identities = 137/438 (31%), Positives = 208/438 (47%), Gaps = 44/438 (10%)
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
PG + +D+TK + +TW P DGG P+L Y++ERR+ G ++PV +
Sbjct: 7983 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENK-LSW 8041
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
TV L+ + EY FRV AVNK G G+ + V+A+DP +PP D+ V + + ++++
Sbjct: 8042 TVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTI 8101
Query: 922 AWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVN 979
W+ P G GYI+E A+ + W +C + + YT GL E ++Y FR+RA N
Sbjct: 8102 TWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAEN 8161
Query: 980 EAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQ 1039
AG+ EP +A+ P APK L++ + V+ G + + A+ SGSP P + W
Sbjct: 8162 AAGISEPSRATPPTKAVDPIDAPK----VILRTSLEVKRGDEIALDASISGSPYPTITWI 8217
Query: 1040 KDG------------------------------VPTKGRETITKS-KNHSQFLINSTKRS 1068
KD +P R +I S K SQ + + R
Sbjct: 8218 KDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP 8277
Query: 1069 DSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNT-VTLTWNHSPDVQEDGE 1127
D G+Y I ++N+ G A+ V V D P PP N +FE++ T V W D
Sbjct: 8278 DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEI 8336
Query: 1128 AHYIIMKRDAS--TATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
+Y + K+D + + W + KY+VT L+ G++Y FRV A N G P S+
Sbjct: 8337 INYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKP 8396
Query: 1186 TWLINKDQIQDLSAKLKP 1203
L+ KD A KP
Sbjct: 8397 --LVAKDPFGPPDAPDKP 8412
Score = 201 bits (510), Expect = 5e-51
Identities = 167/595 (28%), Positives = 274/595 (46%), Gaps = 38/595 (6%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+ P +D L++ I V+ G +A I +PF+G+P P++TW ++ E T+ +V +E+G
Sbjct: 17523 EAPELD---LDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD--KVQIEKG 17577
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
+ L+I NC R D+G +LKL+N GS +A + + VLD P PPQ + E+
Sbjct: 17578 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQN-LAVKEVRKDSAF 17636
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAV 779
+ W+ P +GG V +++++R +K++ + K T+F + EG Y FR++A
Sbjct: 17637 LVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSK-TSFKVENLTEGAIYYFRVMAE 17695
Query: 780 NSEGVSDPLET-EEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
N GV P+ET + V A P PPG + +TDV++ + ++ W P DGG+ VLGY+V
Sbjct: 17696 NEFGVGVPVETVDAVKAAEPPSPPGKVT---LTDVSQTSASLMWEKPEHDGGSRVLGYVV 17752
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
E + KG+ W V + + V GL EY+FRV A N+ G P V V+AKD
Sbjct: 17753 EMQPKGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 17810
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGT 958
P L + + S + L P G P E K+ T++ + T
Sbjct: 17811 LTIQPSLKLPFN-TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQ---TTRVNVEET 17866
Query: 959 C-YTVGGLIERQKYFF---RIRAVNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSH 1013
TV + E K F + A N AG E + + + PP +FD + +
Sbjct: 17867 ATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFD---EVSAD 17923
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
VV + A G + I +K T ++ + + I K +
Sbjct: 17924 FVVISWEP---PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQF 17980
Query: 1074 RILLQNEFGE-ARYDIHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE- 1127
RI +N +G+ A D + + P PP + + + + W H P V + G
Sbjct: 17981 RIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQW-HEP-VNDGGTK 18038
Query: 1128 -AHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
Y + +++ ++ W + + K+ TGL G +Y F+V A N +G +P
Sbjct: 18039 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKP 18093
Score = 200 bits (509), Expect = 7e-51
Identities = 157/596 (26%), Positives = 262/596 (43%), Gaps = 26/596 (4%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+PP + +L+A A +KVG T + +G P PKVTW K+ + + R+ +
Sbjct: 10717 EPPEL---ILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPV 10773
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
+ L I N ED G+ L ++N GS T ++ + VLD+P PP+ +E E+ +
Sbjct: 10774 GSK--LEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRD-LEVSEIRKDSCY 10830
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAV 779
+ WK P D+GG +T ++VERR V W + K ++F+ + + EG Y FR+ A
Sbjct: 10831 LTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH-LNEGNQYLFRVAAE 10889
Query: 780 NSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
N G +ET + + A +P+ PPG DV K V++ WN P +DGG+P+ GY+V
Sbjct: 10890 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 10949
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
E +++G+ W+ + +C V GL + Y FRV A N G G P + + ++
Sbjct: 10950 EYQEEGTQDWIKFK--TVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDT-TIPIECQE 11006
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPA--EGDP-PSGYILEMRAEDTKEWSKCTKIPI 955
+ PP + D+ + + R PA G P P+ +E + +
Sbjct: 11007 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11066
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
+ T+ + R ++I N AG + V + V +P P ++ HM
Sbjct: 11067 FSSVLTIKNCLRRDTGEYQITVSNAAG-SKTVAVHLTVLDVPGPPTGPINILDVTPEHMT 11125
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
+ GSP + I +K ++ + ++ I ++ V+R+
Sbjct: 11126 ISWQPP----KDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRV 11181
Query: 1076 LLQNEFG-----EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHY 1130
+N+ G ++ + P PP + + N T++W P
Sbjct: 11182 RAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWT-LPKSDGGSPITG 11240
Query: 1131 IIMKRDASTATWYTAAERVFSN-KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
M+R T W + ++ K+ VTGL G Y FRV A N G S+P S D
Sbjct: 11241 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11296
Score = 196 bits (497), Expect = 2e-49
Identities = 174/653 (26%), Positives = 280/653 (42%), Gaps = 42/653 (6%)
Query: 567 VHKLIFPSMGPEHEGKYTFRAKGTESEASV---------FIADPPTIDPSVLEALAAHAI 617
V +L + G E KY +R E++A V AD ++P++ + +
Sbjct: 6849 VPELTYKVTGLEKGNKYLYRVSA-ENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGL 6907
Query: 618 TVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGL 677
V V + I VP G P P TW + +RV M+ A L IS R D G+
Sbjct: 6908 EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGI 6967
Query: 678 ILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFI 737
LKL+N + + + ++V+ RP P+ ++F +++ VH+ W+ P D+GG P+T ++
Sbjct: 6968 YTLKLENRVKTISGEIDVNVIARPSAPK-ELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 7026
Query: 738 VERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAG 796
VE+R V +K+W K+ + + F+ + +GK Y F++ A N G +P +E V
Sbjct: 7027 VEKREVSRKTWTKVMDFVTDL-EFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMS 7085
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
P P + D T ++ +TW+ P DGG+ + GYIVER +GS+ WV +P+
Sbjct: 7086 TPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACG-EPV 7144
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
TK V GL E Y +RV A+N+ G +PS P+ + A D + P + D+ +
Sbjct: 7145 AETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLT 7204
Query: 917 SSISLAWREPAE-GDPPSGYILEMRAEDTKEWSK---CTKIPISGTCYTVGGLIERQKYF 972
PA P I +A+ + K +P T T+
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKST-VTIVDSKRSDTGT 7263
Query: 973 FRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSP 1032
+ I AVN G V + PPAA FD++ ++ GS
Sbjct: 7264 YIIEAVNVCGRATAVVEVNVLDKPGPPAA--FDITDVTNESCLLTWNPP----RDDGGSK 7317
Query: 1033 PPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---------- 1082
+ + ++ ++ ++ + + F + ++R+ +N +G
Sbjct: 7318 ITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPI 7377
Query: 1083 EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATW 1142
A+Y D P PPT L + + VTLTW D Y + + D T W
Sbjct: 7378 TAKYQF-----DPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKW 7432
Query: 1143 YTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQI 1194
+ V Y V GL +KY FRV+A N G +P S + LI KD I
Sbjct: 7433 VRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI-KDPI 7484
Score = 196 bits (497), Expect = 2e-49
Identities = 143/520 (27%), Positives = 238/520 (45%), Gaps = 28/520 (5%)
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
L+ P+PP E L+++ S V + W PKD+GG VT + +ER+ W++ +
Sbjct: 23829 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 23888
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKE 816
T ++ + YQFRI+A N G+S+ E V +P + P + ++ ++K+
Sbjct: 23889 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 23948
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
+VT+ W P DGG +LGY VE R+ G + W NK+ I+ + T+ GLLE TEYEFRV
Sbjct: 23949 SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRV 24008
Query: 877 IAVNKAGPGQPSVPSSSVVAK-DPVKPPGLVQDLH-----VSDSSNSSISLAWREPAEGD 930
A N+ G +P + S+ K + PG+ +++ + +++ S + R
Sbjct: 24009 FAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGR------ 24062
Query: 931 PPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKY--FFRIRAVNEAGVGEPVE 988
P I R S+ K+ G +T+ + E Q+ + A NE G E
Sbjct: 24063 -PLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVG-----E 24116
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGR 1048
++ + + A P+F LK G+ L +H + G P P + W +
Sbjct: 24117 VETSSKLLLQ-ATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNS 24175
Query: 1049 ETIT-KSKNHSQFLI--NSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLF 1105
E IT ++ H L+ N +++ +G Y++ L N FG + V + D P PT +
Sbjct: 24176 ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVI 24235
Query: 1106 EEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDAST-ATWYTAAERVFSNKYTVTGLLPGR 1163
E + N+ ++W D +Y++ K +A A W + + + L
Sbjct: 24236 EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENA 24295
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203
YYFRV A+N G S+PL+ +I K + A KP
Sbjct: 24296 GYYFRVSAQNTFGISDPLEVSSVVII-KSPFEKPGAPGKP 24334
Score = 195 bits (496), Expect = 2e-49
Identities = 163/617 (26%), Positives = 271/617 (43%), Gaps = 43/617 (6%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ E ++ + + W P +GG + +IVERR + WIK +
Sbjct: 15158 PDPPKNP-EVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR 15216
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVT 819
+ + + EG Y+FRI+A N+ G+S P T + A + + PG P+V D ++ +++
Sbjct: 15217 YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSIS 15276
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLEDTEYEFRVIA 878
I WN P DGG+ + GY+VE + W V ++ T T+ GL E+ EY+ R+ A
Sbjct: 15277 IAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYA 15336
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPG--LVQDLHVSDSSNSSISLAWREPAEGDPPSGYI 936
+N G G+P++ + A+D + PP L DL + + +L P +G P
Sbjct: 15337 MNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPE-- 15394
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
++ + + K + S + G + R I V + + ++ VR +
Sbjct: 15395 VKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVN--VRVL 15452
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKS 1054
P P+ LK V + L GS + I +K K T+ +
Sbjct: 15453 DTPGPPQ-----DLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATN 15507
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNT 1111
+ + + ++ + S +R+L +NE+G A V+ ++ P PP + L + N+
Sbjct: 15508 CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS 15567
Query: 1112 VTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFR 1168
V+L+W + DG + YI+ + + W T A V + T+TGL+ G +Y FR
Sbjct: 15568 VSLSWEKP---EHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFR 15623
Query: 1169 VVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQ 1228
V A+NE G S+P + LS P KD P F TVL G+
Sbjct: 15624 VSAQNEKGISDP--------------RQLSV---PVIAKDLVIPPAFKLLFNTFTVLAGE 15666
Query: 1229 DCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVE 1288
D + F+G P P VT +K +V + ++ ST L I +D G Y V +
Sbjct: 15667 DLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLT 15726
Query: 1289 NELGKDRSSCTLTVYDK 1305
N G+ + + V DK
Sbjct: 15727 NSAGEAIETLNVIVLDK 15743
Score = 193 bits (491), Expect = 8e-49
Identities = 124/393 (31%), Positives = 189/393 (48%), Gaps = 9/393 (2%)
Query: 799 IEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG 858
++ PG +V+++ K++ +TW P DGG+ + Y+VERR S W P++ +
Sbjct: 10810 LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKK 10869
Query: 859 TKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSS 918
+ L E +Y FRV A N+ G G + A DP+ PPG +DLH D +
Sbjct: 10870 SHFAKH-LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTE 10928
Query: 919 ISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIR 976
+SL W +P G P +GY++E + E T++W K + + V GL + + Y FR++
Sbjct: 10929 VSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTV--TNLECVVTGLQQGKTYRFRVK 10986
Query: 977 AVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
A N G+G P + + P +L +L +VV+AGT + A G P P
Sbjct: 10987 AENIVGLGLP-DTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTA 11045
Query: 1037 IWQKDGVPTKGRETIT-KSKNHSQFL-INSTKRSDSGVYRILLQNEFGEARYDIHVRVAD 1094
W DG K E T ++ N S L I + R D+G Y+I + N G +H+ V D
Sbjct: 11046 KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD 11105
Query: 1095 FPRPPTN-LRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNK 1153
P PPT + + + P +T++W D +YI+ K+D TW + K
Sbjct: 11106 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 11165
Query: 1154 YTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDT 1186
+ L G +Y FRV A N+IG PLDS T
Sbjct: 11166 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPT 11198
Score = 193 bits (491), Expect = 8e-49
Identities = 194/806 (24%), Positives = 335/806 (41%), Gaps = 105/806 (13%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
W KDG + G+++ Q + L S+ + G YT A+ + S TI
Sbjct: 12832 WKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSA------TIK 12885
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKD----GMEVT-----EEERVSM 656
VL+ K G A +K+ ++W G E+T + E
Sbjct: 12886 LKVLD---------KPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRP 12936
Query: 657 ERGEDQALLTISNC-----VREDSGLILLKLKNDHGSATATL-HLSVLDRPKPPQGRVE- 709
+ A + I++C + + +N +G ++ P P GR +
Sbjct: 12937 NWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 12996
Query: 710 --FLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVE 767
++ + + WK P D+GG P+T +++E+R +W K+ ++
Sbjct: 12997 PVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQ 13056
Query: 768 EGKAYQFRILAVNSEGVSDPLETEEV-FAGNPIEPPGFASQPQVTDVTKEAVTITWNAPT 826
EG Y+FR+ A+N G P + + +A +P PPG + P+V D T+ +V+++W P
Sbjct: 13057 EGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13116
Query: 827 QDGGAPVLGYIVERRKKGSNLWVPVN-KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPG 885
DGG+P++GY+VE ++ S+ WV N +Q T+ V GL+EDT+Y+FRV AVNK G
Sbjct: 13117 YDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYS 13176
Query: 886 QPSVPSSSVVAKDPVKPPG--LVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAED 943
PS KD + PP L DL + + +++ P +G PP
Sbjct: 13177 DPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKIT------- 13229
Query: 944 TKEWSKCTKIPISGTCYTVGGLIERQKY--FFRIRAVNEAGVGEPV----------ELDK 991
WSK P +G I+ + F R VN+ G+ + E
Sbjct: 13230 ---WSK----PNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTI 13282
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI 1051
V+ + P P ++ +K A GSP + + QK K T+
Sbjct: 13283 VVKVLDTPGPP---VNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 13339
Query: 1052 TKSKNHSQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRLFE 1106
T + + F + + + S +R+ +NE+G E R V+ + P P +L++
Sbjct: 13340 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTPGPVVDLKVRS 13397
Query: 1107 EVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTAT--WYTAAERVFSNKYTVTGLLPGRK 1164
++ ++ W DG + I D T W + + S +Y+ L G++
Sbjct: 13398 VSKSSCSIGWKKP---HSDGGSRIIGYVVDFLTEENKWQRVMKSL-SLQYSAKDLTEGKE 13453
Query: 1165 YYFRVVARNEIGDSEPLDSRDTWLINKDQI--QDLSAKLKP---YEKKDWRHAPRFVTPL 1219
Y FRV A NE G+ P + ++ +D + DL K P Y K+ + R P+
Sbjct: 13454 YTFRVSAENENGEGTP---SEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF-RLKIPI 13509
Query: 1220 KPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKD 1279
K G P P+V+ KG+ + +++ S++ TL++ C D
Sbjct: 13510 K-----------------GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSD 13552
Query: 1280 SGDYSVLVENELGKDRSSCTLTVYDK 1305
+G Y++ ++N G + ++ V K
Sbjct: 13553 AGKYTITLKNVAGTKEGTISIKVVGK 13578
Score = 193 bits (490), Expect = 1e-48
Identities = 138/458 (30%), Positives = 214/458 (46%), Gaps = 43/458 (9%)
Query: 749 IKIGEVDGKV------------TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
+K G+VDG++ T+ + V + ++ + NS G T V
Sbjct: 16477 VKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRV--- 16533
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
++ P +VT++TK++V+ITW P DGG+ + YIVE+R+ + V +
Sbjct: 16534 --LDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTN-C 16590
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+D L E Y FRV A N+ G G P+ + + + +PPG + V D +
Sbjct: 16591 HKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKIT---VDDVTR 16647
Query: 917 SSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+S+SL+W +P G YI+EM+A+ +++WS+C ++ T L + ++Y FR
Sbjct: 16648 NSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVIT--NLTQGEEYLFR 16705
Query: 975 IRAVNEAGVGEPVELDKGVRA----MPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSG 1030
+ AVNE G +P L + A + P P F S V+ G L I SG
Sbjct: 16706 VVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAF-------SSYSVQVGQDLKIEVPISG 16758
Query: 1031 SPPPDVIWQKDGVPTK--GRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDI 1088
P P + W KDG+P K R +T S + + I T + D G Y I + N G+ I
Sbjct: 16759 RPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASI 16818
Query: 1089 HVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDG--EAHYIIMKRDASTATWYTA 1145
+ D P PP F++V ++TL+WN P + G +YI+ KRD +T W
Sbjct: 16819 EIVTLDKPDPPKGPVKFDDVSAESITLSWN--PPLYTGGCQITNYIVQKRDTTTTVWDVV 16876
Query: 1146 AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ V VT L G +Y FR+ A N G S L+S
Sbjct: 16877 SATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALES 16914
Score = 191 bits (486), Expect = 3e-48
Identities = 152/474 (32%), Positives = 218/474 (45%), Gaps = 34/474 (7%)
Query: 730 GRPVTQF-IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVS--- 785
G P+ F IV R K +W K+G +D V + V+ F ++ ++ S
Sbjct: 12124 GCPIRLFAIVRGRPAPKVTWRKVG-IDNVVRKGQVDLVD---TMAFLVIPNSTRDDSGKY 12179
Query: 786 -----DPLETEEVFAG-NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE 839
+P + VF ++ PG S +V+DVTK + ++W P DGG+ V YIVE
Sbjct: 12180 SLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVE 12239
Query: 840 RRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDP 899
+R+ W V + ++ T V L+ EY FRV AVN+ GPG P+ V+A DP
Sbjct: 12240 KREADRKTWSTVTPE-VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12298
Query: 900 VKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAED--TKEWSKCTKIPI 955
+ P + L V++ + +S +LAW P G GYI R E+ W++ + +
Sbjct: 12299 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYS--VV 12356
Query: 956 SGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
V GL E +KY FR+ A N GV P E + A PK + +
Sbjct: 12357 KDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI----LMPEQIT 12412
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
++AG L I A G P P W+K D V T + K+ + S +I R DSG Y
Sbjct: 12413 IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYY 12472
Query: 1074 RILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEA---H 1129
+ +N G I V V D P PP ++ + +L+W H P EDG + +
Sbjct: 12473 SLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSW-HIP--LEDGGSNITN 12529
Query: 1130 YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
YI+ K D S W TA V V L+PG++Y FRV A N G SEPL S
Sbjct: 12530 YIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTS 12583
Score = 191 bits (485), Expect = 4e-48
Identities = 165/599 (27%), Positives = 252/599 (42%), Gaps = 54/599 (9%)
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L+A I V G I GKP P VTW + E T + ++E + + I
Sbjct: 10029 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMN--ERTLPQEATIETTAISSSMVIK 10086
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
NC R G+ L KN+ G T+ + VLD P P L+ + W +P+D+
Sbjct: 10087 NCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDD 10146
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG P+T +++E+R +++W + + N + + +GKAY FRI A NS G+ +
Sbjct: 10147 GGSPITNYVIEKRESDRRAWTPVTYTVTR-QNATVQGLIQGKAYFFRIAAENSIGMGPFV 10205
Query: 789 ETEEVFA-GNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNL 847
ET E PI P +V +VTK VT+TWN P DGG+ ++ Y++E R G+
Sbjct: 10206 ETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEK 10265
Query: 848 WVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQ 907
+ V D + K TV GL E YE+RV AVN G G+PS + + KD + PP L
Sbjct: 10266 FHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL 10325
Query: 908 DLH--VSDSSNSSISLAWREPAEGDPPSGYILEMR--AEDTKEWSKCTKIPI-------- 955
D ++ + +L R + P + + ED + K T +
Sbjct: 10326 DFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAK 10385
Query: 956 ---SGT-CYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLK 1011
SG C V +K F ++ V+ G PP FD K
Sbjct: 10386 RSDSGKYCVVVENSTGSRKGFCQVNVVDRPG--------------PPVGPVSFD--EVTK 10429
Query: 1012 SHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSG 1071
+MV+ L GS + I +K V +T + + ++
Sbjct: 10430 DYMVISWKPPL----DDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY 10485
Query: 1072 VYRILLQNEFG--------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQ 1123
++RI +N +G + RV D P P + E ++ +TWN D
Sbjct: 10486 IFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPI---VTEVTKDSALVTWNKPHDGG 10542
Query: 1124 EDGEAHYIIMKRDASTATWYTAAERVFS--NKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
+ +YI+ KR+ + W + K+ V LL G +Y FRV A NEIG +P
Sbjct: 10543 KP-ITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDP 10600
Score = 191 bits (484), Expect = 5e-48
Identities = 126/394 (31%), Positives = 187/394 (47%), Gaps = 11/394 (2%)
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
N ++ PG +VT+VTKE TI+W P +GG+ + +IVE RK W V D
Sbjct: 11500 NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVT 11559
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 916
+ + LL + EY FRV A NK G G + ++A +P+ PG ++LH++D
Sbjct: 11560 K--RLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGK 11617
Query: 917 SSISLAWREP--AEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
+ + L WR P G P Y +E R + + +W + K I T Y V +E Q Y FR
Sbjct: 11618 TFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFR 11677
Query: 975 IRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPP 1034
++ NE G + V+ ++ V P DL +L + V+AG + + A G P P
Sbjct: 11678 VQTKNEGGESDWVKTEE-VVVKEDLQKPVLDL--KLSGVLTVKAGDTIRLEAGVRGKPFP 11734
Query: 1035 DVIWQKDGVPT----KGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHV 1090
+V W KD T R I + S+F + KRSD G Y + N G V
Sbjct: 11735 EVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATV 11794
Query: 1091 RVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF 1150
V D P P NL++ + + T+ W+ D +YI+ K + W T + V
Sbjct: 11795 NVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVL 11854
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ TVT L+ G +Y FRV A N+IG P +S+
Sbjct: 11855 TPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESK 11888
Score = 189 bits (481), Expect = 1e-47
Identities = 158/580 (27%), Positives = 258/580 (44%), Gaps = 42/580 (7%)
Query: 619 VKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLI 678
V+ G + + + ++G+P P W K ++ R + + + LT+ NC R D+G
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL--RADIHTTDSFSTLTVENCNRNDAGKY 21929
Query: 679 LLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIV 738
L ++N+ GS + T + VLD P PP G + F +++ + W AP +GG + ++V
Sbjct: 21930 TLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGARIHHYVV 21988
Query: 739 ERRAVGKKSWIKIGEVDGKVTN--FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG 796
E+R ++SW I E K T F N + EG Y FR+ AVN GV +P E E
Sbjct: 21989 EKREASRRSWQVISE---KCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVA 22045
Query: 797 NPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI 856
E P + V D +K + + W P DGG+ + GY++E R+KGS+ WV
Sbjct: 22046 T--EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGH--T 22101
Query: 857 QGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPP-----GLVQDLHV 911
+ TV+ L+E TEYEFRV A N AG +P SSV+ K+P P G+ L +
Sbjct: 22102 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQL-I 22160
Query: 912 SDSSNSSISLAWREPAEGDPP---SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ + S ++ P G P + + EMR ++T S T T TV +
Sbjct: 22161 TCKAGSPFTI--DVPISGRPAPKVTWKLEEMRLKETDRVSITT--TKDRTTLTVKDSMRG 22216
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAF 1028
+ + N AGV + + V P P ++S+ V+ G
Sbjct: 22217 DSGRYFLTLENTAGV-KTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEP----KDG 22271
Query: 1029 SGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR-YD 1087
G+ + I +K T + + S +Q + + +R+ +N FG ++ +
Sbjct: 22272 GGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLE 22331
Query: 1088 IHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTA 1140
+A+ P PT ++ N +++ W + DG + Y + K++ +T
Sbjct: 22332 SAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWE---EPYHDGGSKIIGYWVEKKERNTI 22388
Query: 1141 TWYTAAE-RVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
W + Y VTGL+ G +Y FR A N G S+
Sbjct: 22389 LWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSK 22428
Score = 189 bits (480), Expect = 2e-47
Identities = 192/770 (24%), Positives = 305/770 (39%), Gaps = 73/770 (9%)
Query: 570 LIFPSMGPEHEGKYTFRAKGTESEAS------VFIADPPTIDPSVLEALAAHAITVKVGH 623
L+ P G YT A AS V P + P E+++A +T+
Sbjct: 9684 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSW-- 9741
Query: 624 TAHIKVPFRGKPLPKVTWYK-DGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKL 682
P + K+T Y + E + V + + TI + + +
Sbjct: 9742 -----FPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMA 9796
Query: 683 KNDHGSA--------TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
+N +G TA SV P P ++ + + + W+ P+ +GG PVT
Sbjct: 9797 QNKYGIGEPLDSEPETARNLFSVPGAPDKPT----VSSVTRNSMTVNWEEPEYDGGSPVT 9852
Query: 735 QFIVERRAVGKKSWIKIGEVDGKV----TNFSTNKVEEGKAYQFRILAVNSEGVSDP-LE 789
+ +E + K W ++ K ++ + EG YQFR+ A+N+ GV L
Sbjct: 9853 GYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLP 9912
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
++ A +PI PPG P+VTD TK + + W+ P +DGG+ V GYIVE +++G W
Sbjct: 9913 SDPATARDPIAPPG-PPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWE 9971
Query: 850 PVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDL 909
++GTK V GL E Y+FRV AVN AG G+P + + KD + P L D
Sbjct: 9972 KGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDA 10031
Query: 910 HVSDSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIE 967
V D R A G PP M + + IS + +
Sbjct: 10032 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSM-VIKNCQR 10090
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
+ + + A NEAG + + V +P P F +H + L +
Sbjct: 10091 SHQGVYSLLAKNEAGERKKTII-VDVLDVPGPVGTPF------LAHNLTNESCKLTWFSP 10143
Query: 1028 FS--GSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG--- 1082
GSP + + +K + +T + + + + +RI +N G
Sbjct: 10144 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10203
Query: 1083 --EARYDIHVRVA-DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDA 1137
E + +R P P +L + E NTVTLTWN P + G +Y++ R
Sbjct: 10204 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWN--PPKYDGGSEIINYVLESRLI 10261
Query: 1138 STATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQD 1196
T ++ + + S KYTV GL G Y +RV A N +G +P
Sbjct: 10262 GTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP---------------- 10305
Query: 1197 LSAKLKPYEKKDWRHAPRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITA 1255
S KP KD P + +R G+ +T + G P+P V+ +K + ++
Sbjct: 10306 -SFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10364
Query: 1256 NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+ + +T L DSG Y V+VEN G + C + V D+
Sbjct: 10365 DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 10414
Score = 188 bits (477), Expect = 3e-47
Identities = 110/321 (34%), Positives = 176/321 (54%), Gaps = 12/321 (3%)
Query: 590 TESEASVFIADP---PTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
+E +V DP PTID L H I V G I VPFR P+P V+W+KDG
Sbjct: 7875 SEISENVVAKDPDCKPTID------LETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGK 7928
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
EV +R++M+ A L + VR D+G+ + L+N GSATA++++ V+ P P +
Sbjct: 7929 EVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKD 7988
Query: 707 RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKV 766
++ +++ S + W+ P+ +GG P+ +++ERR G++++I + + K++ + +
Sbjct: 7989 -IKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLI 8047
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
G+ Y FR+ AVN G + +E + V A +P +PP +V + T EA+TITW P
Sbjct: 8048 PNGE-YFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPP 8106
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPG 885
DGG+ ++GYI+E+ KG W N+ + T GL E EY+FRV A N AG
Sbjct: 8107 LYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGIS 8166
Query: 886 QPSVPSSSVVAKDPVKPPGLV 906
+PS + A DP+ P ++
Sbjct: 8167 EPSRATPPTKAVDPIDAPKVI 8187
Score = 187 bits (475), Expect = 6e-47
Identities = 164/601 (27%), Positives = 274/601 (45%), Gaps = 52/601 (8%)
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
PP I+ L+A +T++ T + VP +G+P P+V W +D E ++ S+E
Sbjct: 15360 PPEIE---LDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGE--SLDKASIESTS 15414
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHM 720
LL + N R DSG +L ++N GS +A +++ VLD P PPQ ++ E++ + V +
Sbjct: 15415 SYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQD-LKVKEVTKTSVTL 15473
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W P +GG + +IVE+R +K++ + K T++ ++++EG +Y FR+LA N
Sbjct: 15474 TWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHK-TSWKVDQLQEGCSYYFRVLAEN 15532
Query: 781 SEGVSDPLET-EEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE 839
G+ P ET E V A PPG + + DVT+ +V+++W P DGG+ +LGYIVE
Sbjct: 15533 EYGIGLPAETAESVKASERPLPPG---KITLMDVTRNSVSLSWEKPEHDGGSRILGYIVE 15589
Query: 840 RRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDP 899
+ KGS+ W ++ T+ T+ GL++ EY FRV A N+ G P S V+AKD
Sbjct: 15590 MQTKGSDKWATC--ATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDL 15647
Query: 900 VKPPGLV-----------QDLHVSDS--SNSSISLAWREPAEGDPPSGYILEMRAEDTKE 946
V PP +DL V + ++ W + + P + AE T+
Sbjct: 15648 VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWH---KDNVPLKQTTRVNAESTEN 15704
Query: 947 WSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE-LDKGVRAMPPPAAPKFD 1005
S T I C G + ++ N A GE +E L+ V P P
Sbjct: 15705 NSLLT---IKDACREDVG-------HYVVKLTNSA--GEAIETLNVIVLDKPGPPTGPVK 15752
Query: 1006 LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINST 1065
+ + + G GS + I +K T + ++ + +
Sbjct: 15753 MDEVTADSITLSWGPP----KYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRL 15808
Query: 1066 KRSDSGVYRILLQNEFGEARY-DIHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSP 1120
K +RI +N +G++ Y + VA + P PP + +++ + WN
Sbjct: 15809 KTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPI 15868
Query: 1121 DVQEDGEAHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
Y + +++ ++ W + + K+ TGL G +Y FRV A N +G +
Sbjct: 15869 SDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGK 15928
Query: 1180 P 1180
P
Sbjct: 15929 P 15929
Score = 187 bits (474), Expect = 8e-47
Identities = 184/687 (26%), Positives = 294/687 (42%), Gaps = 94/687 (13%)
Query: 560 QIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT------------ESEASVFIADPPTIDPS 607
+I K + + F G +Y FR K ES + I PP ++
Sbjct: 11355 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVE-- 11412
Query: 608 VLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
L+ ITV+VG T I +G+P P +TW K+G + E+RV + + + L I
Sbjct: 11413 -LDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQI 11471
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKD 727
VR D G ++ KN G A + ++VLDRP P Q +C + W+ P D
Sbjct: 11472 KEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCT-ISWENPLD 11530
Query: 728 NGGRPVTQFIVERRAVGKKSW-IKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSD 786
NGG +T FIVE R +K W I +V ++ + E Y FR+ A N GV
Sbjct: 11531 NGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNE---YYFRVCAENKVGVGP 11587
Query: 787 PLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGS 845
+ET+ + A NPI+ PG + D K V + W P DGG+P L Y VERR KGS
Sbjct: 11588 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11647
Query: 846 NLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL 905
+ W V+K I+ T VD +E+ YEFRV N+ G V + VV K+ ++ P
Sbjct: 11648 DDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVVKEDLQKP-- 11704
Query: 906 VQDLHVSD----SSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT 961
V DL +S + +I L E P + + +D + ++ ++ I +
Sbjct: 11705 VLDLKLSGVLTVKAGDTIRL---EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADS 11761
Query: 962 VGGLIERQKYF----FRIRAVNEAG----------VGEP----------VELDKGVRAMP 997
+ + K + + A N AG + +P V D+
Sbjct: 11762 SKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWD 11821
Query: 998 PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNH 1057
P P+ D ++++++ + T + + +S + V T G T+T+
Sbjct: 11822 P---PEDDGGCEIQNYILEKCETKRMVWSTYSAT-----------VLTPG-TTVTRLIEG 11866
Query: 1058 SQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRLFEEVPNTV 1112
+++ ++R+ +N+ G E++ I D P P + + +
Sbjct: 11867 NEY-----------IFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEM 11915
Query: 1113 TLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGRKYYFRV 1169
T+ WN P + G++ Y + K++ + W + + V LLP +Y FRV
Sbjct: 11916 TVVWN--PPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRV 11973
Query: 1170 VARNEIGDSEP-LDSRDTWLINKDQIQ 1195
A NEIG EP L SR ++ KD I+
Sbjct: 11974 KAENEIGIGEPSLPSRP--VVAKDPIE 11998
Score = 185 bits (470), Expect = 2e-46
Identities = 136/460 (29%), Positives = 206/460 (44%), Gaps = 20/460 (4%)
Query: 730 GRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE 789
GRP + R ++I E T S + + A ++ + NS G
Sbjct: 17553 GRPTPEITWSREEGEFTDKVQI-EKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 17611
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
T +V ++ PG V +V K++ + W P DGGA V Y++++R+ +
Sbjct: 17612 TVKV-----LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYA 17666
Query: 850 PVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDL 909
V+ T V+ L E Y FRV+A N+ G G P +V A +P PPG V
Sbjct: 17667 NVSSK-CSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVT-- 17723
Query: 910 HVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIE 967
++D S +S SL W +P G GY++EM+ + T++WS + + T GL
Sbjct: 17724 -LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVT--GLSS 17780
Query: 968 RQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA 1027
Q+Y FR++A NE G +P L V A P L S ++AG L I
Sbjct: 17781 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYS---IQAGEDLKIEIP 17837
Query: 1028 FSGSPPPDVIWQKDGVPTKG--RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR 1085
G P P++ W KDG P K R + ++ + I + D G Y + N G A
Sbjct: 17838 VIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTAT 17897
Query: 1086 YDIHVRVADFPRPPTNLRLFEEVP-NTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
++ V V + P PP F+EV + V ++W ++YI+ KRD +T TW+
Sbjct: 17898 ENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHM 17957
Query: 1145 AAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR 1184
+ V +T L G +Y FR+ A N G S PLDS+
Sbjct: 17958 VSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSK 17997
Score = 184 bits (467), Expect = 5e-46
Identities = 129/458 (28%), Positives = 206/458 (44%), Gaps = 17/458 (3%)
Query: 732 PVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE 791
P + + R + +++ I+ + + + + +G + +LA N G E +
Sbjct: 10057 PTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV---YSLLAKNEAG-----ERK 10108
Query: 792 EVFAGNPIEPPGFASQPQVT-DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP 850
+ + ++ PG P + ++T E+ +TW +P DGG+P+ Y++E+R+ W P
Sbjct: 10109 KTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTP 10168
Query: 851 VNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLH 910
V + TV GL++ Y FR+ A N G G S ++V ++P+ P +DL
Sbjct: 10169 VTYT-VTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE 10227
Query: 911 VSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
V + + ++++L W P G Y+LE R T+++ K T + YTV GL E
Sbjct: 10228 VKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEG 10287
Query: 969 QKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAF 1028
Y +R+ AVN G G+P K + A P L R K + +R G A + +
Sbjct: 10288 DTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDK--LTIRVGEAFALTGRY 10345
Query: 1029 SGSPPPDVIWQKD--GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
SG P P V W KD V R I + KRSDSG Y ++++N G +
Sbjct: 10346 SGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKG 10405
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNT-VTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTA 1145
V V D P PP F+EV + ++W D +YII K++ W
Sbjct: 10406 FCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV 10465
Query: 1146 AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
V+ LL G+ Y FR+ A N G S+PL S
Sbjct: 10466 TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVS 10503
Score = 183 bits (465), Expect = 8e-46
Identities = 173/660 (26%), Positives = 266/660 (40%), Gaps = 74/660 (11%)
Query: 582 KYTFRAKGT----ESEASVFIADPPTID----PSVLEALAAH-AITVKVGHTAHIKVPFR 632
KY FR K ESE S + P D P V + A + K G I +
Sbjct: 9279 KYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIK 9338
Query: 633 GKPLPKVTW---------YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLK 683
G+P PK +W KDG+ E+ +E E+ +++ I C R +G + K
Sbjct: 9339 GRPTPKSSWEFDGKAKKAMKDGVHDIPED-AQLETAENSSVIIIPECKRSHTGKYSITAK 9397
Query: 684 NDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAV 743
N G TA + V+D P PP+ GSC + WK P D+GG + +++E+R +
Sbjct: 9398 NKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSC-RLSWKMPDDDGGDRIKGYVIEKRTI 9456
Query: 744 GKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLET-EEVFAGNPIEPP 802
K+W K+ G T + + E + Y FR+ A N G+ P+ET + A +PI PP
Sbjct: 9457 DGKAWTKVNPDCGSTTFVVPDLLSE-QQYFFRVRAENRFGIGPPVETIQRTTARDPIYPP 9515
Query: 803 GFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVE-------RRKKGSNLWVPVNKDP 855
+ ++ +TK V ++W P DGG+PV YIVE KK + W NK
Sbjct: 9516 DPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEA--WRQCNKRD 9573
Query: 856 IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPG--LVQDLHVSD 913
++ + TV+ L+E EYEFRV AVN AG +PS + P PP L + + V +
Sbjct: 9574 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEE 9633
Query: 914 SSNSSI----------SLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVG 963
+N +I +L W + P + E + K+ + TC V
Sbjct: 9634 GTNVNIVAKIKGVPFPTLTWFKAPPKKPDN-------KEPVLYDTHVNKLVVDDTCTLVI 9686
Query: 964 GLIERQKY-FFRIRAVNEAGVGEPVELDKGVRAMP-PPAAPKFDLSARLKSHMVVRAGTA 1021
R + I AVN G E+ V P PP P + +S + +
Sbjct: 9687 PQSRRSDTGLYTITAVNNLGTASK-EMRLNVLGRPGPPVGP-----IKFESVSADQMTLS 9740
Query: 1022 LCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEF 1081
GS + + +K K ++ + I V+RI+ QN++
Sbjct: 9741 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKY 9800
Query: 1082 G-----EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRD 1136
G ++ + + P P + N++T+ W Y + +D
Sbjct: 9801 GIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKD 9860
Query: 1137 ASTATWYTA-----AERVFSNKYTVTGLLPGRKYYFRVVARNEIG------DSEPLDSRD 1185
++ W Y VTGL+ G Y FRV A N G S+P +RD
Sbjct: 9861 TTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARD 9920
Score = 182 bits (463), Expect = 1e-45
Identities = 168/649 (25%), Positives = 276/649 (42%), Gaps = 83/649 (12%)
Query: 582 KYTFRAKGTESEASVFIADPPTIDPSV------------LEALAAHAITVKVGHTAHIKV 629
+Y FR SE + +P T+ SV L+A + ++ T + V
Sbjct: 18576 EYNFRICAINSEG---VGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFV 18632
Query: 630 PFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA 689
+G+P P+V W K +T+ R +E +L I N R DSG L L+N+ GS
Sbjct: 18633 TIKGRPEPEVKWEKAEGILTD--RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSK 18690
Query: 690 TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
TA +++ VLD P P + E+ V + W+ P +GG +T +IVE+R +K++
Sbjct: 18691 TAFVNVRVLDSPSAPVN-LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18749
Query: 750 KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQP 808
I K T F ++EG +Y FR+LA N G+ P ET E V P PPG +
Sbjct: 18750 TITNNCTKTT-FRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVT-- 18806
Query: 809 QVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
+ DVT+ TI W P DGG+ + GY+VE + KGS W + ++ + T+ GL
Sbjct: 18807 -LVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTA 18863
Query: 869 DTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE 928
EY FRV AVN+ G P V+A+D P + H + ++ RE +
Sbjct: 18864 GEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH-------TFNVKAREQLK 18916
Query: 929 GDPPSGYILEMRAEDTKEWSK-------CTKIPISG----TCYTVGGLIERQKYFFRIRA 977
D P + R + T W K T++ +S T ++ + + +
Sbjct: 18917 IDVP----FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV 18972
Query: 978 VNEAG-VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP--- 1033
N AG + P+ + V P P P +R C S +PP
Sbjct: 18973 SNSAGSITVPITII--VLDRPGPPGP-------------IRIDEVSCDSITISWNPPEYD 19017
Query: 1034 -----PDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY-D 1087
+ I +K + ++++ + I +R+ +N +G++ Y +
Sbjct: 19018 GGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE 19077
Query: 1088 IHVRVADF----PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWY 1143
VA++ P PP ++ +T+ +TW + Y + ++ S+ W
Sbjct: 19078 SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWS 19137
Query: 1144 TAAERVFSN-KYTVTGLLPGRKYYFRVVARNEIG------DSEPLDSRD 1185
A + + ++ + V+GL G Y +RV A N G EP+ +RD
Sbjct: 19138 KANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARD 19186
Score = 176 bits (447), Expect = 1e-43
Identities = 152/630 (24%), Positives = 264/630 (41%), Gaps = 70/630 (11%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP+ + E ++ + + WK P D+GG +T + VERR W++ +
Sbjct: 14075 PGPPE-KPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLR 14133
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVTKEAVT 819
++EG Y+FR+ A N G+ P E ++ V + PPG S P VTD TK++ +
Sbjct: 14134 CKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSAS 14193
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVP-VNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
+ W P DGG + GY+VE +K G W+ ++ T+ V L +Y FR+ A
Sbjct: 14194 LAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14253
Query: 879 VNKAGPGQPSV-PSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPP----- 932
+N AG G+P+V P +V ++ L +L + + +S+ P +G P
Sbjct: 14254 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTW 14313
Query: 933 --SGYILEMRA--EDTKEWS-----KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV 983
L+ RA E+T+ ++ +C + T+ ++ F +R ++ G
Sbjct: 14314 TKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14373
Query: 984 G---EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK 1040
P ++ K + P D +R+ +++V +K
Sbjct: 14374 VLNLRPTDITKDSVTLHWDL-PLIDGGSRITNYIV-----------------------EK 14409
Query: 1041 DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPR 1097
K T T + + + +R++ +NE+G V+ ++ P
Sbjct: 14410 REATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS 14469
Query: 1098 PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKY 1154
PP +L + + +TV+L W P + DG + Y+I + + W T V +
Sbjct: 14470 PPDSLNIMDITKSTVSLAW---PKPKHDGGSKITGYVIEAQRKGSDQW-THITTVKGLEC 14525
Query: 1155 TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPR 1214
V L G +Y F+V+A N G S P +SR + + + +L + Y+K A
Sbjct: 14526 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLR-GIYQKLVIAKA-- 14582
Query: 1215 FVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPT 1274
G + + LG P+PTVT KGD + + + +T+ L I
Sbjct: 14583 ------------GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINE 14630
Query: 1275 CTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
C DSG Y + N +G+ T+ V+D
Sbjct: 14631 CVRSDSGPYPLTARNIVGEVGDVITIQVHD 14660
Score = 174 bits (442), Expect = 4e-43
Identities = 163/600 (27%), Positives = 259/600 (43%), Gaps = 61/600 (10%)
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
L+A + ++ G T + VP +G+P PK+TW K + + + + ++ + L
Sbjct: 13198 LDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCE 13257
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDN 728
N + D+G +L L+N G T+ + VLD P PP V E+S ++ W+ P +
Sbjct: 13258 NVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVN-VTVKEISKDSAYVTWEPPIID 13316
Query: 729 GGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL 788
GG P+ ++V++R +KSW + K T+F +EEGK+Y FR+ A N G+ DP
Sbjct: 13317 GGSPIINYVVQKRDAERKSWSTVTTECSK-TSFRVANLEEGKSYFFRVFAENEYGIGDPG 13375
Query: 789 ETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW 848
ET + + + PG +V V+K + +I W P DGG+ ++GY+V+ + N W
Sbjct: 13376 ETRDAVKAS--QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTE-ENKW 13432
Query: 849 VPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGL--- 905
V K + + L E EY FRV A N+ G G PS +VVA+D V P L
Sbjct: 13433 QRVMKS--LSLQYSAKDLTEGKEYTFRVSAENENGEGTPS--EITVVARDDVVAPDLDLK 13488
Query: 906 -VQDLHVSDSSNSSISLAWREPAEGDP-PSGYILEMRAEDTKEWSKCTKIPIS--GTCYT 961
+ DL NS+ L + P +G P PS + + ED + S T
Sbjct: 13489 GLPDLCYLAKENSNFRL--KIPIKGKPAPS--VSWKKGEDPLATDTRVSVESSAVNTTLI 13544
Query: 962 VGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAP-KFDLSARLKSHMVVRAGT 1020
V + + I N AG E K V P P KFD + A T
Sbjct: 13545 VYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFD-------EVTAEAMT 13597
Query: 1021 ALCIHAAFSGSPPPD---------VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSG 1071
+PP D ++ ++D V K T + + F +
Sbjct: 13598 -------LKWAPPKDDGGSEITNYILEKRDSVNNKW-VTCASAVQKTTFRVTRLHEGMEY 13649
Query: 1072 VYRILLQNEFG----------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+R+ +N++G AR+ V D P PP + + ++V+LTW
Sbjct: 13650 TFRVSAENKYGVGEGLKSEPIVARHPFD--VPDAPPPP---NIVDVRHDSVSLTWTDPKK 13704
Query: 1122 VQEDGEAHYIIMKRDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
Y + ++ ++ W A + + + VTGL G +Y FRV+A N G +P
Sbjct: 13705 TGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKP 13764
Score = 174 bits (440), Expect = 7e-43
Identities = 143/479 (29%), Positives = 208/479 (43%), Gaps = 77/479 (16%)
Query: 743 VGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPP 802
V KKS + I VD K ++ T +E AVN G V N ++ P
Sbjct: 7245 VPKKSTVTI--VDSKRSDTGTYIIE----------AVNVCG-----RATAVVEVNVLDKP 7287
Query: 803 GFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCT 862
G + +TDVT E+ +TWN P DGG+ + Y+VERR S +W ++ ++ T
Sbjct: 7288 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSST-VKDTNFK 7346
Query: 863 VDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
L+ + EY FRV A N G G+P V +S + AK PPG L SD + +++L
Sbjct: 7347 ATKLIPNKEYIFRVAAENMYGVGEP-VQASPITAKYQFDPPGPPTRLEPSDITKDAVTLT 7405
Query: 923 WREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNE 980
W EP + G P +GY +E DT +W +C K+P+ T Y V GL ++KY FR+ A N
Sbjct: 7406 WCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENL 7465
Query: 981 AGVG------EPVELDKGVRAMPPPAAP-----------------KFDLSARLKSHMV-- 1015
AG G EP+ + + PP P + D A+++S+++
Sbjct: 7466 AGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEM 7525
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
++ GT + A +GVPT +Q L+ +R+
Sbjct: 7526 LKTGTDEWVRVA-------------EGVPT------------TQHLLPGLMEGQEYSFRV 7560
Query: 1076 LLQNEFGEARYD-----IHVRVADFP-RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH 1129
N+ GE+ + R +P PP L + NT L W +
Sbjct: 7561 RAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITN 7620
Query: 1130 YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWL 1188
YI+ KRD W T V K TVT L G Y FRV A N IG S+ + D+ L
Sbjct: 7621 YIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVL 7679
Score = 174 bits (440), Expect = 7e-43
Identities = 141/466 (30%), Positives = 208/466 (44%), Gaps = 32/466 (6%)
Query: 730 GRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFST-------NKVEEGKAYQFRILAVNSE 782
GRP + + V + +IG +D K T+F T NK + GK + + NS
Sbjct: 13222 GRPPPKITWSKPNVNLRD--RIG-LDIKSTDFDTFLRCENVNKYDAGK---YILTLENSC 13275
Query: 783 GVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRK 842
G + E ++ PG V +++K++ +TW P DGG+P++ Y+V++R
Sbjct: 13276 G-----KKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRD 13330
Query: 843 KGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKP 902
W V + T V L E Y FRV A N+ G G P +V A +
Sbjct: 13331 AERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKAS---QT 13386
Query: 903 PGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCY 960
PG V DL V S SS S+ W++P G GY+++ E+ K W + K Y
Sbjct: 13387 PGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKS--LSLQY 13443
Query: 961 TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGT 1020
+ L E ++Y FR+ A NE G G P E+ V A AP DL + + +
Sbjct: 13444 SAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENS 13501
Query: 1021 ALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
+ G P P V W+K D + T R ++ S ++ ++ ++SD+G Y I L+
Sbjct: 13502 NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLK 13561
Query: 1079 NEFGEARYDIHVRVADFPRPPTNLRLFEEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDA 1137
N G I ++V P PT F+EV +TL W D +YI+ KRD+
Sbjct: 13562 NVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13621
Query: 1138 STATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
W T A V + VT L G +Y FRV A N+ G E L S
Sbjct: 13622 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKS 13667
Score = 172 bits (437), Expect = 1e-42
Identities = 175/656 (26%), Positives = 265/656 (40%), Gaps = 95/656 (14%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG-----EVD 755
P PP G+ + L + + + W P DNGG P+T + +E+R G W ++ +V
Sbjct: 9102 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9160
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVT 814
K F+ ++ EG YQFR +A+N+ G+ P E ++ AG+PI PPG S P+V D T
Sbjct: 9161 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKT 9220
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLLEDTEY 872
K ++++ W P +DGG+P+ GYIVE +++G+ W VN+ I +C V L E +Y
Sbjct: 9221 KSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKY 9280
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA----E 928
FRV AVN+AG +PS + + A D + P + D+ D R PA
Sbjct: 9281 RFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGR 9340
Query: 929 GDPPSGYILEMRAE----------------DTKEWSKCTKIPISGTCYTVGGLIERQKYF 972
P S + + +A+ +T E S IP +T KY
Sbjct: 9341 PTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT-------GKY- 9392
Query: 973 FRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALC--IHAAFSG 1030
I A N+AG + V+ M P PK LK + R L + G
Sbjct: 9393 -SITAKNKAG---QKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDDDGG 9443
Query: 1031 SPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG-------- 1082
+ +K + K + + F++ +R+ +N FG
Sbjct: 9444 DRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETI 9503
Query: 1083 ---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM-----K 1134
AR I+ P PP L++ NTV L+W + HYI+
Sbjct: 9504 QRTTARDPIYP-----PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDP 9558
Query: 1135 RDASTATWYTAAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQ 1193
W +R V ++TV L+ G +Y FRV A N G S+P
Sbjct: 9559 TGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP------------- 9605
Query: 1194 IQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNI 1253
SA + P + + P + + V G + + G P PT+T +K
Sbjct: 9606 ----SATVGPCDCQR-PDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKK 9660
Query: 1254 TANSKFWYNST-------SGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
N + T CTLVIP D+G Y++ N LG L V
Sbjct: 9661 PDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9716
Score = 172 bits (437), Expect = 1e-42
Identities = 178/792 (22%), Positives = 321/792 (40%), Gaps = 74/792 (9%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFI------A 599
W+K +E+++ ++I L G Y +AK E SV +
Sbjct: 16080 WIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDR 16139
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
P P V+ + A T+ K P + + + + E + ++
Sbjct: 16140 PGPPEGPVVISGVTAEKCTLAW------KPPLQDGGSDIINYIVERRETSRLVWTVVDAN 16193
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHG--------SATATLHLSVLDRPKPPQGRVEFL 711
++ + + + N +G A V D PK P E
Sbjct: 16194 VQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP----EVT 16249
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK-----IGEVDGKVTNFSTNKV 766
++ + + W+ P +GG + +++E+R W + IGE+ +VT N
Sbjct: 16250 TVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH- 16308
Query: 767 EEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
Y+FR+ A N+ G+S+P A +PI PG + P+V D+T+ +V ++W+ P
Sbjct: 16309 ----DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKP 16364
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLEDTEYEFRVIAVNKAGP 884
DGG + GYIVE+ W I T V+ LLE EY FR+ A+NKAG
Sbjct: 16365 IYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGV 16424
Query: 885 GQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN--SSISLAWREPAEGDPPSGYILEMRAE 942
G+ + ++ ++ ++ P + DL + N + SL P +G P + + + +
Sbjct: 16425 GEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRP-TPEVKWGKVD 16483
Query: 943 DTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAP 1002
+ + S T + + + + N +G VR + P+ P
Sbjct: 16484 GEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVT---VRVLDTPSPP 16540
Query: 1003 KFDLSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
LK + + ++ GS + I +K K + + + + +
Sbjct: 16541 -----VNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSW 16595
Query: 1061 LINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWN 1117
I+ + S +R+ +NE+G A+ ++VA+ P+PP + + + N+V+L+W
Sbjct: 16596 KIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWT 16655
Query: 1118 HSPDVQEDGEAHYI--IMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEI 1175
+ DG + I I++ A + ++ RV S + +T L G +Y FRVVA NE
Sbjct: 16656 KP---EHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEK 16712
Query: 1176 GDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCA 1235
G S+P S ++ KD + + K P F + ++V GQD +
Sbjct: 16713 GRSDPR-SLAVPIVAKDLVIEPDVK------------PAFSS----YSVQVGQDLKIEVP 16755
Query: 1236 FLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDR 1295
G P+PT+T K + + ++ + + TL I D G Y + V N +G+
Sbjct: 16756 ISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKT 16815
Query: 1296 SSCTLTVYDKDD 1307
+S + DK D
Sbjct: 16816 ASIEIVTLDKPD 16827
Score = 171 bits (432), Expect = 6e-42
Identities = 170/661 (25%), Positives = 275/661 (41%), Gaps = 101/661 (15%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P PP + ++++ V +KW+ PK++GGRP+ ++++E++ W+K G+ G N
Sbjct: 7687 PGPPYA-LAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 7745
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFA-GNPIEPPGFASQPQVTDVTKEAVT 819
F V EG QF++ A N GV P E E+ + +P PP VTD ++ +
Sbjct: 7746 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 7805
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVD-GLLEDTEYEFRVIA 878
I W P ++GG+P++GY VE G+ W+ VN PI+ K V+ G++ D EY RV A
Sbjct: 7806 IAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRA 7865
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGL---VQDLHVSDSSNSSISLAWREPAEGDPPSGY 935
VN G +PS S +VVAKDP P + D+ V + SI + +R A P +
Sbjct: 7866 VNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFR--AVPVPTVSW 7923
Query: 936 ILEMRAEDTKEWSKCTKIPISGTCYT----VGGLIERQKYFFRIRAVNEAGVGEPVELDK 991
+D KE ++ + + V + + I N+ G ++
Sbjct: 7924 -----HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG-SATASINV 7977
Query: 992 GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAA-FSGSPP--PDVIWQKDGVPTKGR 1048
V +P P +K+ + ++ L F G P V+ +++ GR
Sbjct: 7978 KVIGLPGPCKD-------IKASDITKSSCKLTWEPPEFDGGTPILHYVLERREA----GR 8026
Query: 1049 ET---ITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR---VADFPR----P 1098
T + +N + + + +R+ N+ G Y I ++ +A P+ P
Sbjct: 8027 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY-IELKNPVIAQDPKQPPDP 8085
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAERVFSN-KYT 1155
P ++ + +T+TW P + + G YII K W E + YT
Sbjct: 8086 PVDVEVHNPTAEAMTITWK--PPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYT 8143
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
GL G++Y FRV A N G SEP S P + D AP+
Sbjct: 8144 AKGLEEGKEYQFRVRAENAAGISEP-----------------SRATPPTKAVDPIDAPKV 8186
Query: 1216 V--TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWY------------ 1261
+ T L+ V RG + + + G+P PT+T K D N+ +
Sbjct: 8187 ILRTSLE---VKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE 8242
Query: 1262 ------------------NSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVY 1303
NS G L + D G Y + VEN+ G ++ CT++V
Sbjct: 8243 VQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVL 8302
Query: 1304 D 1304
D
Sbjct: 8303 D 8303
Score = 169 bits (427), Expect = 2e-41
Identities = 217/939 (23%), Positives = 367/939 (39%), Gaps = 112/939 (11%)
Query: 430 VKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
VK R + ++ + T+ W+KDGQ L T+ +++ L I++A D G Y
Sbjct: 18909 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 18968
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLA---TVKSGMSDVHAATGSPAEL---CVVLNDEKV 542
+ T IV + D + +P E C + N
Sbjct: 18969 ELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISN---- 19024
Query: 543 EGVWLKDGKEITDLPGMQIVKQGAVH---KLIFPSMGPEHEGKYTFR---AKGTESEASV 596
++ + KE T IV Q K++ + G E++ + K + SE+S
Sbjct: 19025 ---YIVEKKETTSTT-WHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSA 19080
Query: 597 FIADPPTIDPS------VLEA-----LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+A+ P P V+ A L + V G + I K + W K
Sbjct: 19081 VVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKAN 19140
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
+ + ++ + G D+ L+ E+ I G + + P P
Sbjct: 19141 KILIADTQMKVS-GLDEGLMYEYRVYAENIAGI--------GKCSKSCEPVPARDPCDPP 19191
Query: 706 GRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNK 765
G+ E ++ V +KW P +GG +T +IVERR + W+K + + T F +
Sbjct: 19192 GQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTE 19251
Query: 766 VEEGKAYQFRILAVNS-EGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDV--TKEAVTIT 821
+ E + Y+FR+ A N+ + VS+P E T + + +EPP + DV K +
Sbjct: 19252 LTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLK 19311
Query: 822 WNAPTQDGGAPVLGYI---VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
NA PV+ + +E ++ + + + K D + DT + +
Sbjct: 19312 INADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVK---DCIRRDTG---QYVL 19365
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYI 936
K G SV + V P P G L ++ + SL+W P E G YI
Sbjct: 19366 TLKNVAGTRSVAVNCKVLDKPGPPAG---PLEINGLTAEKCSLSWGRPQEDGGADIDYYI 19422
Query: 937 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAM 996
+E R W+ C + T V L++ +Y FR+ VN+ GVGEP+E ++A+
Sbjct: 19423 VEKRETSHLAWTICEG-ELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLE-SVAIKAL 19480
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT---- 1052
P P S + S V + LC P D + G + RE +
Sbjct: 19481 DPFTVPSPPTSLEITS--VTKESMTLCW-----SRPESDGGSEISGYIIERREKNSLRWV 19533
Query: 1053 --KSKNHSQFLINST--KRSDSGVYRILLQNEFG---EARYDIHVRVAD---FPRPPTNL 1102
K + ST + YR+ +N G + +R D P PP+
Sbjct: 19534 RVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKP 19593
Query: 1103 RLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYTVTGL 1159
++ + T+T+ W DG A Y + + + W T+ + + +YT++GL
Sbjct: 19594 KIVDSGKTTITIAWVKP---LFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGL 19650
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSRDTWLI---NKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
G +Y FRV + N++G S+P DS D + ++ + D+ ++++
Sbjct: 19651 TTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMR-------------- 19696
Query: 1217 TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
K V G TMT F G P P V K D ++ ++ + ++T +L I
Sbjct: 19697 ---KTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL--RTRAYVDTTDSRTSLTIENAN 19751
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASIT 1315
DSG Y++ ++N L +S TL V D +IT
Sbjct: 19752 RNDSGKYTLTIQNVL--SAASLTLVVKVLDTPGPPTNIT 19788
Score = 167 bits (424), Expect = 5e-41
Identities = 248/1114 (22%), Positives = 419/1114 (37%), Gaps = 162/1114 (14%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRM 317
P K+ W K LR + L D+K L NVN DAG Y L S G K
Sbjct: 13224 PPPKITWSKPNVNLRDRIGL---DIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEY 13280
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEP---------NFVWKFNGKELK 368
+ + VLD P PV VT ++ + ++ + P N+V + E K
Sbjct: 13281 TIVVKVLDTP------GPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERK 13334
Query: 369 R---------DDKYEITVSEDGLTHTLKI---KDARLSDSGEFSAEAGNLVQKAQLTIDR 416
+ + E+G ++ ++ + + D GE + +A Q +D
Sbjct: 13335 SWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGE-TRDAVKASQTPGPVVD- 13392
Query: 417 IPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKK---DGQLLMHGTKYSMNHEGKRA 473
+K RS + C ++ WKK DG + G E +
Sbjct: 13393 -------------LKVRSVSKSSC-------SIGWKKPHSDGGSRIIGYVVDFLTEENKW 13432
Query: 474 ELIIEDAQL-------SDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKS----GMSD 522
+ +++ L ++G EYT + + E + I V G+ D
Sbjct: 13433 QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPD 13492
Query: 523 VH--AATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHK-LIFPSMGPEH 579
+ A S L + + + V K G++ V+ AV+ LI
Sbjct: 13493 LCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSD 13552
Query: 580 EGKYTFRAKGT----ESEASVFIADPPTID--PSVLEALAAHAITVKVGHTAHIKVPFRG 633
GKYT K E S+ + P I P + + A A+T+K P +
Sbjct: 13553 AGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWA-------PPKD 13605
Query: 634 KPLPKVTWY-KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA--- 689
++T Y + + + V+ + ++ + +N +G
Sbjct: 13606 DGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGL 13665
Query: 690 -----TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVG 744
A V D P PP +++ V + W PK GG P+T + +E +
Sbjct: 13666 KSEPIVARHPFDVPDAPPPPN----IVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 13721
Query: 745 KKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP-LETEEVFAGNPIEPPG 803
W + + ++ +F + EG Y+FR++A+N GV P L +E V A +PI+PPG
Sbjct: 13722 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 13781
Query: 804 FASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTV 863
+P+V ++T+ +VT+ W P DGG + GYIVE+R S W+ N + TV
Sbjct: 13782 ---KPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTV 13838
Query: 864 DGLLEDTEYEFRVIAVNKAGP-GQPSVPSSSVVAKDPVKPPGLVQDLHVSD-----SSNS 917
L+E +YEFR+ A N AG PS + +++ KD + P +V D + D + ++
Sbjct: 13839 TDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDT 13898
Query: 918 SISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRA 977
+ A + P S + + + ++ T P S + T+ + + I A
Sbjct: 13899 IVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKDAGEYTITA 13957
Query: 978 VNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV 1036
N G E V++ V +P P P + + +A GSP
Sbjct: 13958 TNPFGTKVEHVKVT--VLDVPGPPGP-----VEISNVSAEKATLTWTPPLEDGGSPIKSY 14010
Query: 1037 IWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR--YDIHVRVAD 1094
I +K +++ + + + + ++R+ N +G+ V++ D
Sbjct: 14011 ILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVD 14070
Query: 1095 F---PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFS 1151
P PP + NT T++W D Y + +R+ + W A + S
Sbjct: 14071 RFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS 14130
Query: 1152 N-KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWR 1210
+ + VTGL G Y FRV A N G P ++ D+ L+ KD
Sbjct: 14131 DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLM-----------------KDAA 14173
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNIT--------ANSKFWYN 1262
+ P P PH D T A L +P Y G + IT + W
Sbjct: 14174 YPPG--PPSNPHVT----DTTKKSASLAWGKPH---YDGGLEITGYVVEHQKVGDEAWIK 14224
Query: 1263 STSG----VCTLVIPTCTLKDSGDYSVLVENELG 1292
T+G + V+P K+ ++ + N+ G
Sbjct: 14225 DTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14258
Score = 167 bits (423), Expect = 6e-41
Identities = 166/658 (25%), Positives = 277/658 (42%), Gaps = 63/658 (9%)
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
+++GA +KL ++ EG T +E +PP ++ L+ I +
Sbjct: 8569 IREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQ----EPPAVE---LDVSVKGGIQIMA 8621
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
G T I G+P+P W K+ E+ +++RV ++ ++ L I + +R+D G ++
Sbjct: 8622 GKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVIDNVGTKSELIIKDALRKDHGRYVIT 8680
Query: 682 LKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERR 741
N GS A + V D P P + C+ + W P+D+GG +T FI+ER+
Sbjct: 8681 ATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCL-LNWSDPEDDGGSEITGFIIERK 8739
Query: 742 AVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEP 801
+W + ++ + + + EG+ Y+FR++A N G P+E + A +P+ P
Sbjct: 8740 DAKMHTWRQ--PIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGP 8797
Query: 802 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
P + T+ TK +T+ W P +GG+P+ GYI+E+R+ + VNK T
Sbjct: 8798 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 8857
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
V+ L E YEFRV AVN+ G +PS+P + V+ D V PP + L V +I +
Sbjct: 8858 LVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEV-PPTIKLRLSV---RGDTIKV 8913
Query: 922 AWREPAEGDPPSGYILEMRAEDTKEWSK-------------CTKIPIS----GTCYTVGG 964
EP P L M EWSK TK +S T ++
Sbjct: 8914 KAGEPVH-IPADVTGLPM---PKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPK 8969
Query: 965 LIERQKYFFRIRAVNEAG-VGEPVELDKGVRAMPPPAAPKFDLSAR---LKSHMVVRAGT 1020
+ K + + A N G V V ++ R PP D+ A L + G
Sbjct: 8970 AVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGG 9029
Query: 1021 ALCIHAAFSGSPPPDVIWQKDGVPTKGR-ETITKSKNHSQFLINSTKRSDSGVYRILLQN 1079
+ H VI ++D K E +T + ++ I + +R+ N
Sbjct: 9030 SEITHY---------VIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVN 9080
Query: 1080 EFG---EARYDIHVRVAD---FPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM 1133
++G E + D V + D P PP ++ ++ ++W D Y +
Sbjct: 9081 KYGISDECKSD-KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLE 9139
Query: 1134 KRDASTATWYTAAERVFSN------KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRD 1185
KR+ + W + + ++ V LL G KY FR +A N G P + D
Sbjct: 9140 KREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSD 9197
Score = 165 bits (417), Expect = 3e-40
Identities = 163/635 (25%), Positives = 271/635 (42%), Gaps = 78/635 (12%)
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
+D +PP+ V ++S + V + W+ P +GG +T +IVERR + W K +
Sbjct: 20268 IDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20326
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEG-------VSDPLETEEVFAGNPIEPPGFASQPQV 810
T F + + + Y+FR+ A N+ G V P+ + + G I+ P +
Sbjct: 20327 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLP-----LEY 20381
Query: 811 TDVTK--EAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
T+V K ++ A AP + + + ++ +N V V + T L++
Sbjct: 20382 TEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCV-----ENTTDLASILIK 20436
Query: 869 DTE------YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
D + YE ++ N G ++ V D PPG + + I+L
Sbjct: 20437 DADRLNSGCYELKLR--NAMGSASATI---RVQILDKPGPPG--GPIEFKTVTAEKITLL 20489
Query: 923 WREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNE 980
WR PA+ G + YI+E R WS ++ + T +I+ +Y FR+RAVN+
Sbjct: 20490 WRPPADDGGAKITHYIVEKRETSRVVWSMVSE-HLEECIITTTKIIKGNEYIFRVRAVNK 20548
Query: 981 AGVGEPVELDKGV--RAMPPPAAPKF-DLSARLKSHMVVRAGTALCIHAAFSGSPPPDVI 1037
G+GEP+E D V A P P +++ K+ M V + A GS
Sbjct: 20549 YGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPI----ADGGSDISGYF 20604
Query: 1038 WQKDGVPTKGRETITKS--KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV--- 1092
+K + G + K ++ Q + T+ SD YR+ N G+ +
Sbjct: 20605 LEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKA 20663
Query: 1093 ---ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAE 1147
D P PP +R+ + +++TL W S V + G A Y++ R W T +
Sbjct: 20664 ADPIDPPGPPAKIRIADSTKSSITLGW--SKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20721
Query: 1148 R--VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYE 1205
+ V + +Y V+ L PG YYFRV A N G EP++ + P +
Sbjct: 20722 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNE-----------------PVQ 20764
Query: 1206 KKDWRHAPRFVTPLKPHTVL---RGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
KD AP + T + G+D + F G P PTVT K + N+ +++++
Sbjct: 20765 AKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE 20824
Query: 1263 STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSS 1297
+T L IP T D+G Y + +EN +G+ +SS
Sbjct: 20825 NTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSS 20859
Score = 165 bits (417), Expect = 3e-40
Identities = 205/927 (22%), Positives = 345/927 (37%), Gaps = 119/927 (12%)
Query: 441 ELTSKDVTLRWK---KDGQLLMHGTKYSMN-HEGKRAELIIEDAQLSDGGEYTVVAMQDG 496
++T + +TL+W +DG + G YS+ +G + +S+ +YTV + G
Sbjct: 21368 DVTRETITLKWNPPLRDGGSKIVG--YSIEKRQGNERWVRCNFTDVSEC-QYTVTGLSPG 21424
Query: 497 D----------------PTEYYSTAIVTVEERLATV----KSGMSDVHAATGSPAELCVV 536
D P S I+T +E + + + +G + +
Sbjct: 21425 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 21484
Query: 537 LNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT----E 591
+ V V W KDG EI M+I L +H G YT AK +
Sbjct: 21485 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 21544
Query: 592 SEASVFIADPP--TIDPSVLEALAAHAITV------KVGHTAHIKVPFRGKPLPKVTW-- 641
+E V + D P + P + +T+ G + ++ W
Sbjct: 21545 AEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWAL 21604
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP 701
+D E + + G + +S + G L D A + +V D P
Sbjct: 21605 IEDKCEAQSYTAIKLINGNEYQF-RVSAVNKFGVGRPL-----DSDPVVAQIQYTVPDAP 21658
Query: 702 KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK-IGEVDGKVTN 760
P+ ++G+ + + W P+ +GG + Q+I+ERR W+K I + T
Sbjct: 21659 GIPEPS----NITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETR 21714
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVT 819
F + EG Y+F ++A N+ GV + P+ PPG + +VTD +K V+
Sbjct: 21715 FKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVS 21774
Query: 820 ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAV 879
+ W+ P DGG ++GYI+E K W VN + T+ TV L EY+FRV A+
Sbjct: 21775 LEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAI 21834
Query: 880 NKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDS----SNSSISL------------AW 923
N AG G + ++ A D + P L D + + + +SI L W
Sbjct: 21835 NGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVW 21894
Query: 924 REPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV 983
+P I + T C + TV + F ++ ++ G
Sbjct: 21895 SKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP 21954
Query: 984 GEPVELDKGVRAMPPPA--APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKD 1041
P+ R AP D AR+ ++V +K
Sbjct: 21955 PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVV-----------------------EKR 21991
Query: 1042 GVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR-YDIH--VRVADFPRP 1098
+ + I++ F +N +R+ NE+G Y++ + + P P
Sbjct: 21992 EASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAP 22051
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYT 1155
P L + + ++ L W PD DG + Y++ R + W A +T
Sbjct: 22052 PRRLDVVDTSKSSAVLAWL-KPD--HDGGSRITGYLLEMRQKGSDFWVEAGHTK-QLTFT 22107
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
V L+ +Y FRV A+N+ G SEP ++ + +I + QI+ +A L
Sbjct: 22108 VERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP-TADLTGITN--------- 22157
Query: 1216 VTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
+ T G T+ G P P VT ++ + + +T TL +
Sbjct: 22158 ----QLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 22213
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTV 1302
DSG Y + +EN G S T+ V
Sbjct: 22214 MRGDSGRYFLTLENTAGVKTFSVTVVV 22240
Score = 164 bits (416), Expect = 4e-40
Identities = 230/1109 (20%), Positives = 416/1109 (37%), Gaps = 125/1109 (11%)
Query: 268 WIKGTEPLRIQYSLGKYDVKQMGT------KYMLVISNVNMNDAGIYSL----SVGDKRM 317
++ G P + +++ + + Q T +VI N + G+YSL G+++
Sbjct: 10050 YVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKK 10109
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDK----- 372
+ + VLD P +T + + + + ++ + D +
Sbjct: 10110 TIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPV 10169
Query: 373 -YEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVK 431
Y +T + ++ K + E S G V+ ++ + R PI +++ VK
Sbjct: 10170 TYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVK 10229
Query: 432 ERSRACLECELTSKDVTLRWKKD----GQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGE 487
E +T VTL W G +++ S ++ + D LS +
Sbjct: 10230 E---------VTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSR--K 10278
Query: 488 YTVVAMQDGDPTEYYSTAI--------------VTVEERLA------------TVKSGMS 521
YTV +++GD EY +A+ +T ++ LA T++ G
Sbjct: 10279 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVG-- 10336
Query: 522 DVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEG 581
+ A TG + K + W KD ++ + I A L G
Sbjct: 10337 EAFALTGRYS------GKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSG 10390
Query: 582 KYTFRAKGTES------EASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKP 635
KY + + + +V P + P + + + + K P
Sbjct: 10391 KYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISW------KPPLDDGG 10444
Query: 636 LPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLH- 694
+ + EV ++ + + + +S + + + +N +G + +
Sbjct: 10445 SKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSD 10504
Query: 695 -LSVLDRPKPPQGRVEFL--ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKI 751
+ DR + P + + E++ + W P D GG+P+T +I+E+R K W ++
Sbjct: 10505 SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARV 10563
Query: 752 GEVD-GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQ 809
+ T F + EG Y+FR+ A N G+ DP ++ VFA +PI P P+
Sbjct: 10564 TKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPE 10623
Query: 810 VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLL 867
D T +V +TW P DGG+ +LGYIVE +K G W N P TK V GL
Sbjct: 10624 AIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLR 10683
Query: 868 EDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA 927
+ Y+FRV+AVN AG P+ V+ KD ++PP L+ D +++ + + R A
Sbjct: 10684 DGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSA 10743
Query: 928 --EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
+G P + D ++ P+ G+ + + + N AG
Sbjct: 10744 IIKGVPFPKVTWKKEDRDAPTKARIDVTPV-GSKLEIRNAAHEDGGIYSLTVENPAG--- 10799
Query: 986 PVELDKGVRAMPPPAAPK-FDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP 1044
+ V + P P+ ++S K + L GS + + ++ V
Sbjct: 10800 SKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPL----DDGGSVITNYVVERRDVA 10855
Query: 1045 TKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY---DIHVRVADF---PRP 1098
+ ++ + + ++R+ +N++G + ++ D P P
Sbjct: 10856 SAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGP 10915
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKRDASTATWYTAAERVFSNKYT 1155
P +L + V+L WN PD DG + Y++ ++ T W + V + +
Sbjct: 10916 PKDLHHVDVDKTEVSLVWN-KPD--RDGGSPITGYLVEYQEEGTQDWIKF-KTVTNLECV 10971
Query: 1156 VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRF 1215
VTGL G+ Y FRV A N +G P D + ++ EK
Sbjct: 10972 VTGLQQGKTYRFRVKAENIVGLGLP---------------DTTIPIECQEKLVPPSVELD 11016
Query: 1216 VTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
V ++ V G G P PT I + + + + L I C
Sbjct: 11017 VKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNC 11076
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
+D+G+Y + V N G + LTV D
Sbjct: 11077 LRRDTGEYQITVSNAAGSKTVAVHLTVLD 11105
Score = 163 bits (412), Expect = 1e-39
Identities = 149/604 (24%), Positives = 259/604 (42%), Gaps = 43/604 (7%)
Query: 598 IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
I + P ID L+ ++ K G + +PF+G+P P VTW KD + + R S+E
Sbjct: 20768 ILEAPEID---LDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIE 20824
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGS-ATATLHLSVLDRPKPPQGRVEFLELSGS 716
+ +LLTI R D+G +L ++N G ++T+ + VLD P Q +++ +S
Sbjct: 20825 NTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQ-KLQVKHVSRG 20883
Query: 717 CVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRI 776
V + W P +GG P+ +++E+R K++W + T+F + E + FR+
Sbjct: 20884 TVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSS-TSFKLIDLSEKTPFFFRV 20942
Query: 777 LAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGY 836
LA N G+ +P ET E E P + D TK +V ++W P DGG+ + Y
Sbjct: 20943 LAENEIGIGEPCETTEPV--KAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY 21000
Query: 837 IVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVA 896
+VER+ KG W + + V L E + EFRV A N+ G P V +
Sbjct: 21001 VVERKGKGEQTWSHAGIS--KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP-VTIGPITV 21057
Query: 897 KDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPIS 956
K+ + P ++ +SD + +++ + P + + + + W K +P+
Sbjct: 21058 KELIITP----EVDLSDIPGAQVTVRIGHNVHLELP----YKGKPKPSISWLK-DGLPLK 21108
Query: 957 GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV--RAMP-------PPAAPKFDLS 1007
+ + E + A E G V LD V A+P PP+ PK +
Sbjct: 21109 ESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIR 21168
Query: 1008 -ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTK 1066
+K+ V+ + + G +K + + S + F + +
Sbjct: 21169 FDEIKADSVILSWD---VPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLV 21225
Query: 1067 RSDSGVYRILLQNEFGEAR---YDIHVRVADF--PRPPTNLRLFEEVPNTVTLTWNHSPD 1121
+ +R+ +N +G ++ I V F P PP ++ + ++LTW+
Sbjct: 21226 KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWD--AP 21283
Query: 1122 VQEDGE--AHYIIMKRDASTATWYTA-AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
V + G + + K++ ++ W + +Y TGL+ G Y FRV A N G S
Sbjct: 21284 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21343
Query: 1179 EPLD 1182
P D
Sbjct: 21344 SPSD 21347
Score = 162 bits (409), Expect = 3e-39
Identities = 153/668 (22%), Positives = 271/668 (40%), Gaps = 55/668 (8%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+F+ + VTA E + AVF + + + W + + + + K H +
Sbjct: 5433 KFLTPLKDVTAKEKESAVFTVELSHD-NIRVKWFKNDQ-RLHTTRSVSMQDEGKTHSITF 5490
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTV---------SLLVTEGQEKMDF------------ 166
+ L+ DD+ + A ++A TV L G EK +
Sbjct: 5491 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5550
Query: 167 KKMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMK 226
K K P K A+ K+ + IL K K D + + G G K
Sbjct: 5551 VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTDKTSG--------K 5602
Query: 227 KKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIW-IKGTEPLRIQYSLGKYD 285
+E I++++PL E T F+ E+ + ++ W +KG L+ +
Sbjct: 5603 LDIEDREIKLVRPLHSVEVMETETARFET--EISEDDIHANWKLKGEALLQTP----DCE 5656
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
+K+ G + LV+ N ++ G + + SA L V + L +K V VT +TA
Sbjct: 5657 IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETA 5716
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
F+ LS ++ W GK+L+ DK + +G HTL ++D +L D+GE A +
Sbjct: 5717 TFDCELSYEDIPVEWYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5774
Query: 406 LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYS 465
A L + P++F L++ V+E + A LECE++ ++ ++W K+G ++ KY
Sbjct: 5775 FKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYE 5834
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ +G+ +L+I D D YT D ++ ++ + V ++D+
Sbjct: 5835 IVADGRVRKLVIHDCTPEDIKTYTC------DAKDFKTSCNLNVVPPHVEFLRPLTDLQV 5888
Query: 526 ATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A L+ E + W KDG EI I+ +GAV L+ + E +Y+
Sbjct: 5889 REKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC 5948
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFR-GKPLPKVTWYKD 644
+ + + + + + + ++V T IK+ KP +V WYK
Sbjct: 5949 EVRTARTSGMLTVLEEEAV-------FTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKG 6001
Query: 645 GMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
E+ E R + + +L I N ED+G +L + +H + P
Sbjct: 6002 DEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKP 6061
Query: 705 QGRVEFLE 712
Q +E LE
Sbjct: 6062 Q-NLEILE 6068
Score = 160 bits (406), Expect = 6e-39
Identities = 256/1157 (22%), Positives = 432/1157 (37%), Gaps = 180/1157 (15%)
Query: 242 DKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVN 301
++ KV T+ I++ P K+ W K R + + DV +G+K L I N
Sbjct: 10730 EQHIKVGDTLRLSAIIK-GVPFPKVTWKKED---RDAPTKARIDVTPVGSK--LEIRNAA 10783
Query: 302 MNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMKPVKVTE-RQTAVFEIRLSKKEP 356
D GIYSL+V G K +S ++ VLD+P G + ++V+E R+ + + L+ KEP
Sbjct: 10784 HEDGGIYSLTVENPAGSKTVSVKVLVLDKP----GPPRDLEVSEIRKDSCY---LTWKEP 10836
Query: 357 ---------NFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGE---FSAEAG 404
N+V ++R D S T K A+ + G F A
Sbjct: 10837 LDDGGSVITNYV-------VERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 10889
Query: 405 NLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKK---DGQLLMHG 461
N + PIK + L + ++ +V+L W K DG + G
Sbjct: 10890 NQYGRGPFVETPKPIKALDPL---HPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITG 10946
Query: 462 TKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYY-------------STAIVT 508
EG + + + E V +Q G + +T +
Sbjct: 10947 YLVEYQEEGTQDWIKFKTV---TNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIE 11003
Query: 509 VEERLATVKSGM-----SDVHAATGSPAELCVVLNDEKV-EGVWLKDGKEITDLPGMQIV 562
+E+L + + G+ ++ V W DG EI +
Sbjct: 11004 CQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE 11063
Query: 563 KQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVF-------IADPPTIDPSVLEALAAH 615
L + G+Y +V + PPT ++L+ H
Sbjct: 11064 TDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEH 11123
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDS 675
T + P P + + + + ++ + G + L I + +
Sbjct: 11124 M-------TISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCE 11176
Query: 676 GLILLKLKNDHG-----SATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGG 730
+ ++ +N G +T T+ P PP G+ +++ + + W PK +GG
Sbjct: 11177 YVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPP-GKPVVTDITENAATVSWTLPKSDGG 11235
Query: 731 RPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL-E 789
P+T + +ERR V K W+++ + F + EG Y+FR+ A N G+S P
Sbjct: 11236 SPITGYYMERREVTGK-WVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 11294
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
++ + A PI+PPG P++ D ++E + W P DGG+P+LGY+VE +K G+ W
Sbjct: 11295 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWN 11354
Query: 850 PVNKDP-IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQD 908
+NKD I+ V GL+E EY FR+ A N G G+P + SV+AKD + PP + D
Sbjct: 11355 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 11414
Query: 909 LHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+ D + R A ++ R E W+K G ++ R
Sbjct: 11415 VTCRDVITVRVGQTIRILAR--------VKGRPEPDITWTK------------EGKVLVR 11454
Query: 969 QKYFFRIRAVN--EAGVGEPVELDKGVRAMPPPAAPKFDLSARLKS---------HMVVR 1017
+K I+ + E + E V D G K+ +SA+ S +++ R
Sbjct: 11455 EKRVDLIQDLPRVELQIKEAVRADHG----------KYIISAKNSSGHAQGSAIVNVLDR 11504
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT---------KSKNHSQFLINSTKR- 1067
G + + W+ G IT K S + TKR
Sbjct: 11505 PGPCQNLKVTNVTKENCTISWENP--LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRL 11562
Query: 1068 -------SDSGVYRILLQNEFG-----EARYDI-HVRVADFPRPPTNLRLFEEVPNTVTL 1114
++ +R+ +N+ G E + I + D P P NL + ++ V L
Sbjct: 11563 IKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYL 11622
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAE-RVFSNKYTVTGLLPGRKYYFRVVARN 1173
W Y + +R + W + + Y V + + Y FRV +N
Sbjct: 11623 KWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKN 11682
Query: 1174 EIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPH---TVLRGQDC 1230
E G+S+ + + + ++ K+ +Q KP V LK TV G
Sbjct: 11683 EGGESDWVKTEE--VVVKEDLQ------KP------------VLDLKLSGVLTVKAGDTI 11722
Query: 1231 TMTCAFLGNPRPTV--TLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVE 1288
+ G P P V T K ++T + + ++ + + D G Y V
Sbjct: 11723 RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTAT 11782
Query: 1289 NELGKDRSSCTLTVYDK 1305
N G + T+ V DK
Sbjct: 11783 NTAGSFVAYATVNVLDK 11799
Score = 160 bits (406), Expect = 6e-39
Identities = 157/655 (23%), Positives = 275/655 (41%), Gaps = 61/655 (9%)
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDR-----PKPPQGRVEFLELSG 715
++ ++T + ++ + + ++ N +G SV+ + P PP G E +++
Sbjct: 20524 EECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITK 20582
Query: 716 SCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFR 775
+ + + W P +GG ++ + +E+R W K+ + + T + E YQ+R
Sbjct: 20583 NSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYR 20642
Query: 776 ILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVL 834
+ AVN+ G E E + A +PI+PPG ++ ++ D TK ++T+ W+ P DGG+ V
Sbjct: 20643 VCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 20702
Query: 835 GYIVERRKKGSNLWVPVN-KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSS 893
GY+VE R+ W V+ K ++ T+ V L Y FRV AVN AG G+P +
Sbjct: 20703 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 20762
Query: 894 VVAKDPVKPPGLVQD--LHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCT 951
V AKD ++ P + D L S + + + P +G PP +D K
Sbjct: 20763 VQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWR---KDEKNLGSDA 20819
Query: 952 KIPISGT----CYTVGGLIERQ--KYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFD 1005
+ I T T+ + KY I E GVGEP V+ + PAA +
Sbjct: 20820 RYSIENTDSSSLLTIPQVTRNDTGKYILTI----ENGVGEPKSSTVSVKVLDTPAACQ-- 20873
Query: 1006 LSARLKSHMVVRAGTALCIHAAF--SGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLIN 1063
+L+ V R L GSP + + +K + ++ + + F +
Sbjct: 20874 ---KLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI 20930
Query: 1064 STKRSDSGVYRILLQNEFG---EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
+R+L +NE G V+ A+ P P +L + + +V L+W P
Sbjct: 20931 DLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWT-KP 20989
Query: 1121 DVQEDGEA---HYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGD 1177
D DG + Y++ ++ TW A + + V+ L FRV A+NE G
Sbjct: 20990 DF--DGGSVITEYVVERKGKGEQTWSHAGISK-TCEIEVSQLKEQSVLEFRVFAKNEKGL 21046
Query: 1178 SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT---PLKPHTVLRGQDCTMTC 1234
S+P+ + P K+ P P TV G + +
Sbjct: 21047 SDPVT------------------IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLEL 21088
Query: 1235 AFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVEN 1289
+ G P+P+++ K + + + ++ T TL I + G Y+V+++N
Sbjct: 21089 PYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN 21143
Score = 154 bits (389), Expect = 5e-37
Identities = 157/664 (23%), Positives = 267/664 (40%), Gaps = 60/664 (9%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+ ++KP+ VTA E F V + P + W +S + IK S K S K H L L
Sbjct: 2750 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKS-VEIKPSDKHRLVSERKVHKLML 2807
Query: 128 EPLTSDDSDNYKCIASNDHADA-IYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
+ ++ D+ Y + A ++ +L +T+ + ++ P+ K
Sbjct: 2808 QNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKNIE-----------VPETKTASFE 2856
Query: 187 NEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVE---------------- 230
E + S K E E +G L +L M E
Sbjct: 2857 CEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSA 2916
Query: 231 ---VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
V I I L+D + T+ F+ + + + K W+K ++ S K ++
Sbjct: 2917 TLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYK--WLKNGVEIK---STDKCQMR 2971
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+ L I NV+ DA Y+ G +A L V ++F +K +KV E++ A+F
Sbjct: 2972 TKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMF 3031
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E +S+ + W + +EL+ D+ I + ++ H L I R+SD+G+++ AG V
Sbjct: 3032 ECEVSEPDITVQWMKDDQELQITDR--IKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNV 3089
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A+L ++ ++ S K V+V E+ RA +E E+ DV W KDG + +
Sbjct: 3090 STAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3149
Query: 468 H--EGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ E + + I + + SD GEYT VA ++ Y A V + V
Sbjct: 3150 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNA-----PEPPQVLQELQPVTV 3204
Query: 526 ATGSPAELCVVLNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
+G PA C V++ + W K+ + ++ + + G + L+ PE YT
Sbjct: 3205 QSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYT 3264
Query: 585 FRAKG----TESEASVFIADPPTIDPSVLEALAAHAITVKV-------GHTAHIKVPFRG 633
AK + AS+ + P + P + AI + G A + G
Sbjct: 3265 CEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG 3324
Query: 634 KPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
L KV+WY ++ M + ED L I+ ED G N G ++T
Sbjct: 3325 TDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTA 3383
Query: 694 HLSV 697
+LS+
Sbjct: 3384 NLSL 3387
Score = 152 bits (385), Expect = 2e-36
Identities = 151/601 (25%), Positives = 256/601 (42%), Gaps = 58/601 (9%)
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
+ P ID L+ I ++ G + + VP +G+P P+V W K E+ + + +
Sbjct: 16441 EAPDID---LDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSS 16497
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
L + N R DSG L L+N G+ +A + + VLD P PP ++ E++ V
Sbjct: 16498 FTS--LVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVN-LKVTEITKDSVS 16554
Query: 720 MKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTN-----KVEEGKAYQF 774
+ W+ P +GG + +IVE+R +KS+ + VTN N +++EG +Y F
Sbjct: 16555 ITWEPPLLDGGSKIKNYIVEKREATRKSYAAV------VTNCHKNSWKIDQLQEGCSYYF 16608
Query: 775 RILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPV 833
R+ A N G+ P +T + + +PPG + V DVT+ +V+++W P DGG+ +
Sbjct: 16609 RVTAENEYGIGLPAQTADPIKVAEVPQPPGKIT---VDDVTRNSVSLSWTKPEHDGGSKI 16665
Query: 834 LGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSS 893
+ YIVE + K S W + ++ + + L + EY FRV+AVN+ G P +
Sbjct: 16666 IQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP 16723
Query: 894 VVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKI 953
+VAKD V P V+ S S L P G P +D + T+I
Sbjct: 16724 IVAKDLVIEPD-VKPAFSSYSVQVGQDLKIEVPISGRPKPTITW---TKDGLPLKQTTRI 16779
Query: 954 PISGTC-YTVGGLIERQK---YFFRIRAVNEAGVG----EPVELDKGVRAMPPPAAPKFD 1005
++ + T + E K + I N G E V LDK PP KFD
Sbjct: 16780 NVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK---PDPPKGPVKFD 16836
Query: 1006 ----LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
S L + + G G + I QK T + ++ + +
Sbjct: 16837 DVSAESITLSWNPPLYTG----------GCQITNYIVQKRDTTTTVWDVVSATVARTTLK 16886
Query: 1062 INSTKRSDSGVYRILLQNEFGEA-RYDIHVRVADF----PRPPTNLRLFEEVPNTVTLTW 1116
+ K +RI +N +G++ + VA + P PP +++ + W
Sbjct: 16887 VTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQW 16946
Query: 1117 NHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGRKYYFRVVARNEI 1175
+ + Y + +++ ++ W + + ++ L G +Y FRV A N +
Sbjct: 16947 HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIV 17006
Query: 1176 G 1176
G
Sbjct: 17007 G 17007
Score = 151 bits (381), Expect = 5e-36
Identities = 228/1018 (22%), Positives = 388/1018 (38%), Gaps = 103/1018 (10%)
Query: 224 EMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQY---- 279
EM + V+ + I LE E +D + I + + +I KG P + +
Sbjct: 20758 EMNEPVQAKDI-----LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDE 20812
Query: 280 ----SLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGD-----KRMSAELTVLDEPLKF 330
S +Y ++ + +L I V ND G Y L++ + K + + VLD P
Sbjct: 20813 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 20872
Query: 331 LGEMKPVKVTERQTAVFE-----IRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHT 385
+ VK R T I N+V +++ D + T S ++H
Sbjct: 20873 --QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYV-------IEKRDATKRTWSV--VSHK 20921
Query: 386 LKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSK 445
+L D E + ++ + ++ I P + +K V R + T
Sbjct: 20922 CSSTSFKLIDLSEKTPFFFRVLAENEIGIGE-PCETTEPVKAAEVPAPIRDLSMKDSTKT 20980
Query: 446 DVTLRWKK---DGQLLMHGTKYSMNHEGKRAELI----------IEDAQLSDGG--EYTV 490
V L W K DG ++ T+Y + +GK + IE +QL + E+ V
Sbjct: 20981 SVILSWTKPDFDGGSVI--TEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRV 21038
Query: 491 VAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT-----GSPAELCVVLNDEKVEGV 545
A + ++ + +TV+E + T + +SD+ A G L + + +
Sbjct: 21039 FAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI 21098
Query: 546 -WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIA----D 600
WLKDG + + ++ K L + EH GKYT +V I
Sbjct: 21099 SWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLG 21158
Query: 601 PPT--IDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME- 657
PP+ P + + A ++ + VP ++T Y T + M
Sbjct: 21159 PPSKPKGPIRFDEIKADSVILS------WDVP-EDNGGGEITCYSIEKRETSQTNWKMVC 21211
Query: 658 RGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDR-----PKPPQGRVEFLE 712
+ + N V++ ++ +N +G + + ++ + P PP G+
Sbjct: 21212 SSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GKPVIYN 21270
Query: 713 LSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAY 772
++ + + W AP +GG VT F VE++ W K+ + + EG Y
Sbjct: 21271 VTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDY 21330
Query: 773 QFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA 831
QFR+ A NS G+S P + + A +P++PPG P DVT+E +T+ WN P +DGG+
Sbjct: 21331 QFRVYAENSAGLSSPSDPSKFTLAVSPVDPPG---TPDYIDVTRETITLKWNPPLRDGGS 21387
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGP-GQPSVP 890
++GY +E+R +G+ WV N + + TV GL YEFR+IA N G PS
Sbjct: 21388 KIVGYSIEKR-QGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQS 21446
Query: 891 SSSVVAKDPVKPPGLVQDLHVSDS--SNSSISLAWREPAEGDP-PSGYILEMRAEDTKEW 947
S ++ +D PP + D S SL + +G P P + E K
Sbjct: 21447 SGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM 21506
Query: 948 SKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLS 1007
+ + T V + + + A N +G + E+ V+ P +
Sbjct: 21507 NMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK-AEIKVKVQDTPGKVVGPIRFT 21565
Query: 1008 ARLKSHMV------VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE-TITKSKNHSQF 1060
M + G A H + W + + T K N +++
Sbjct: 21566 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEY 21625
Query: 1061 LINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSP 1120
+ + GV R L + I V D P P + N++TLTW
Sbjct: 21626 QFRVSAVNKFGVGRPL---DSDPVVAQIQYTVPDAPGIPEPSNI---TGNSITLTWARPE 21679
Query: 1121 DVQEDGEAHYIIMKRDASTATWYTAAER--VFSNKYTVTGLLPGRKYYFRVVARNEIG 1176
YI+ +R+ + W + + ++ VTGL G +Y F V+A N G
Sbjct: 21680 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 21737
Score = 148 bits (373), Expect = 4e-35
Identities = 228/958 (23%), Positives = 368/958 (38%), Gaps = 159/958 (16%)
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMI-WIKGTEPLRIQYSLGKYDV 286
K++VEA++I K L++ VF +EL PNVK + WIK L S KY +
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFT--VELTHPNVKGVQWIKNGVVLE---SNEKYAI 2709
Query: 287 KQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAV 346
GT Y L I N + D +Y +G SA L V E +K + + K V E T
Sbjct: 2710 SVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHV--ETVKIIKKPKDVTALENATVA 2767
Query: 347 FEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
FE+ +S W E+K DK+ + VSE + H L +++ SD+GE++A G L
Sbjct: 2768 FEVSVSHDTVPVKWFHKSVEIKPSDKHRL-VSERKV-HKLMLQNISPSDAGEYTAVVGQL 2825
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
KA+L ++ + I +KN+ V E A ECE++ +V W K+G + K+ +
Sbjct: 2826 ECKAKLFVETLHI--TKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKI 2883
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
+GK +LII + D EYT V D +A +TV + T S + D++A
Sbjct: 2884 VVQGKLHQLIIMNTSTEDSAEYTFVCGND------QVSATLTVTPIMIT--SMLKDINAE 2935
Query: 527 TGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
V +N E + WLK+G EI Q+ + H L ++ YTF
Sbjct: 2936 EKDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFV 2995
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPL-------PKV 639
A S A++++ A H K H IKV + + + P +
Sbjct: 2996 AGKATSTATLYVE-------------ARHIEFRK--HIKDIKVLEKKRAMFECEVSEPDI 3040
Query: 640 T--WYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
T W KD E+ +R+ +++ + L I + D+G K G +T L V
Sbjct: 3041 TVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAG----KYTVVAGGNVSTAKLFV 3096
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
R R+ ++ + + R V +F V V W K DG
Sbjct: 3097 EGRDV----RIRSIKKEVQVIEKQ---------RAVVEFEVNEDDVDAH-WYK----DGI 3138
Query: 758 VTNFSTNKVEEGKAY----QFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDV 813
NF +V+E Y + + ++ SD E V N + + P+ V
Sbjct: 3139 EINF---QVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQV 3195
Query: 814 TKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE 873
+E +T Q G ++ R + W + G KC L + EY
Sbjct: 3196 LQELQPVT----VQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKF--LHDGQEYT 3249
Query: 874 FRVI-------------AVNKAGPGQPSVPSS----SVVAKD---PVKPPGLV---QDLH 910
+I A N G S S VV+ D PV PP ++ QD
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3309
Query: 911 VSDS---------SNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT 961
S+ S + + ++W + PS + + EDT + P YT
Sbjct: 3310 TSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYT 3369
Query: 962 ------VGGL------------------------IERQKYFFRIRAVNEAGV-GEPVELD 990
VG + +E +++ + E G+ ++L
Sbjct: 3370 FVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLS 3429
Query: 991 K-----GVRAMPPPAAPKFD--------LSARLKSHMVVRAGTALCIHAAFSGSPPPDVI 1037
K + + P KFD + + S+ + G + G P P +
Sbjct: 3430 KINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQ 3489
Query: 1038 WQKDGV---PTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV 1092
W +GV P+ + + +HS +I TK D G Y + N++G+ ++++
Sbjct: 3490 WFFNGVLLTPSADYKFVFDGDDHS-LIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3546
Score = 147 bits (371), Expect = 7e-35
Identities = 156/631 (24%), Positives = 257/631 (40%), Gaps = 77/631 (12%)
Query: 702 KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNF 761
KP RV + + + V + W P+D GG VT +++E + V + W K K+ +
Sbjct: 23538 KPQNPRVT--DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREY 23595
Query: 762 STNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGFASQPQVTD--VTKEAV 818
+ + +G Y+FR+LA N+ G +P E V +E P + + + ++
Sbjct: 23596 TLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGG 23655
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN--------KDPIQGTKCTVDGLLEDT 870
I P + P+ + E + + + K+ +G T D +LE
Sbjct: 23656 VIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLE-- 23713
Query: 871 EYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE-- 928
NK G + +V V P P G L D S+ ++WR PA+
Sbjct: 23714 ---------NKCG--KKAVYIKVRVIGSPNSPEG---PLEYDDIQVRSVRVSWRPPADDG 23759
Query: 929 GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE 988
G GYILE R W + GT V GL E +Y FR+ A N+ G+ +P++
Sbjct: 23760 GADILGYILERREVPKAAWYTIDS-RVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLK 23818
Query: 989 LDKGVRAMPP--PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPT 1045
++ V P P P + L V ++ +L S S P D + G
Sbjct: 23819 SEEPVTPKTPLNPPEPPSNPPEVLD---VTKSSVSL------SWSRPKDDGGSRVTGYYI 23869
Query: 1046 KGRETIT-KSKNHSQFLINSTKRSDSGV-------YRILLQNEFGEARYD------IHVR 1091
+ +ET T K H++ I +T + +G+ +RI+ QN+ G + +
Sbjct: 23870 ERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 23929
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA-HYIIMKRDASTATWYTA-AERV 1149
D P P L + ++VTL W P+ E Y + R + + W + ER+
Sbjct: 23930 PFDKPSQPGELEILSISKDSVTLQWE-KPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 23988
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
++T+ GLL +Y FRV A NE G S P + + KL E
Sbjct: 23989 KDKQFTIGGLLEATEYEFRVFAENETGLSRP----------RRTAMSIKTKLTSGE---- 24034
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
AP +K T G+ ++C +G P P + Y+ + + K+ +S T
Sbjct: 24035 --APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHT 24092
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
L + T +D G Y+ + NE+G+ +S L
Sbjct: 24093 LTVMTEEQEDEGVYTCIATNEVGEVETSSKL 24123
Score = 146 bits (368), Expect = 1e-34
Identities = 152/685 (22%), Positives = 274/685 (40%), Gaps = 60/685 (8%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+F + VT PE +A F + A ++ W + I IK S K + K+H+L +
Sbjct: 4990 DFAVPLKDVTVPERRQARFECVLTREA--NVIWSKGPDI-IKSSDKFDIIADGKKHILVI 5046
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTVSLL------------VTEGQEKMDFKKMLKKRAP 175
DD Y A V+ + V EG+ ++ ++
Sbjct: 5047 NDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMH 5106
Query: 176 PAPKKKQKKVANEKEML-EILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAI 234
K K+ + +L K K + ++V ++ D + ++KE+ +++ +
Sbjct: 5107 VVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLD----DISQIKAQVKELSSTAQLKVL 5162
Query: 235 R----ILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
L DK + C + KD VK W K E + KY +K G
Sbjct: 5163 EADPYFTVKLHDKTAVEKDEITLKCEVS-KDVPVK--WFKDGEEI---VPSPKYSIKADG 5216
Query: 291 TKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIR 350
+ +L I ++ D G Y G + A +TV +K + V+V +TA FEI
Sbjct: 5217 LRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIE 5276
Query: 351 LSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKA 410
LS+ + + WK G+ L EI EDG H L + + +L +GE S +A N A
Sbjct: 5277 LSEPDVHGQWKLKGQPLTASPDCEII--EDGKKHILILHNCQLGMTGEVSFQAANAKSAA 5334
Query: 411 QLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEG 470
L + +P+ F++ L +V+V E+ A ECE++ + T RW K Q + ++ + +G
Sbjct: 5335 NLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDG 5394
Query: 471 KRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSP 530
+ ++I+ A D +Y A + +++ + +E + + DV A
Sbjct: 5395 TKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKFLTPLKDVTAKEKES 5448
Query: 531 AELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
A V L+ + + W K+ + + + + +G H + F + + + A G
Sbjct: 5449 AVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGM 5508
Query: 591 ESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTE 650
SEA + + + DP L + K ++ P V W+KDG E+
Sbjct: 5509 SSEAKLTVLEG---DPYFTGKLQDYTGVEKDEVILQCEISKADAP---VKWFKDGKEIKP 5562
Query: 651 EERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP---KPPQGR 707
+ ++ + +L + ++ D G + D G+ + L + DR P
Sbjct: 5563 SKNAVIKADGKKRMLILKKALKSDIG----QYTCDCGTDKTSGKLDIEDREIKLVRPLHS 5618
Query: 708 VEFL---------ELSGSCVHMKWK 723
VE + E+S +H WK
Sbjct: 5619 VEVMETETARFETEISEDDIHANWK 5643
Score = 143 bits (361), Expect = 1e-33
Identities = 192/826 (23%), Positives = 330/826 (39%), Gaps = 134/826 (16%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA-KIFYDSINKEHVL 125
P+ V P+PV EG+ A FR RV G +P ++W + K ++ YD I H L
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGI---HYL 1851
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPK------ 179
+ S D+ K A N + V L E Q++ DF+ +L++ P P+
Sbjct: 1852 DIVDCKSYDTGEVKVTAENPEGVIEHKVKL---EIQQREDFRSVLRRAPEPRPEFHVHEP 1908
Query: 180 -------------------------KKQKKVANEK---EMLEILSKVPKKDFEKVCMEYG 211
K+ +++ +EK E E+ SK ++ E
Sbjct: 1909 GKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAIT 1968
Query: 212 FTDFRGLLR--KLKEMKKKVEVEAIRILKPLEDKETK----------------------- 246
+ + + +E+ +K + E + K L ++E K
Sbjct: 1969 AVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPS 2028
Query: 247 VDTTVVFDCIME---------------LKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGT 291
++ +F+ I + P+ + W K ++I+ S Y
Sbjct: 2029 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNG--VKIERSDRIYWYWPEDN 2086
Query: 292 KYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPL-KFLGEMKPVKVTERQT-A 345
LVI +V D+ + G+ A L V + L F E++ V E+ T A
Sbjct: 2087 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2146
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSA---E 402
FE S+ W +G E+ DKY + D H L I SD+ ++S E
Sbjct: 2147 TFECETSEPFVKVKWYKDGMEVHEGDKYRM--HSDRKVHFLSILTIDTSDAEDYSCVLVE 2204
Query: 403 AGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGT 462
N+ A+L ++ ++FV L+++ V E LEC ++ +++ +W + L
Sbjct: 2205 DENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNG 2264
Query: 463 KYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSD 522
KY++ R L ++D D GEY+ V DG T T + ++ R + G+SD
Sbjct: 2265 KYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKT----TCKLKMKPRPIAILQGLSD 2318
Query: 523 VHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGK 582
G +L V ++ E VEGVW+KDG+E+ + IV H L+ M E G
Sbjct: 2319 QKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGN 2378
Query: 583 YTFR----AKGTESEASVFIAD--PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPL 636
Y+F T SV+ D P D +V+E K + VP +
Sbjct: 2379 YSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEG-------TKAVLECKVSVP----DV 2427
Query: 637 PKVTWYKDGMEVTEEERV-SMERGEDQALLTISNCVREDSG---LILLKLKNDHGSATAT 692
V WY + ++ ++RV ++ +G Q L+ I+ D G LI+ +++ + +
Sbjct: 2428 TSVKWYLNDEQIKPDDRVQAIVKGTKQRLV-INRTHASDEGPYKLIVGRVETNCNLSVEK 2486
Query: 693 LHL--SVLDRPKPPQGRVEF-LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
+ + + D V F +ELS S + + W KD +P +++ +E K +
Sbjct: 2487 IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNF-KDKEIKPSSKYKIEAHGKIYKLTV 2545
Query: 750 --KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEV 793
+ + +GK T ++ + GK L V +S PL + V
Sbjct: 2546 LNMMKDDEGKYTFYAGENMTSGK------LTVAGGAISKPLTDQTV 2585
Score = 143 bits (360), Expect = 1e-33
Identities = 157/639 (24%), Positives = 271/639 (42%), Gaps = 54/639 (8%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P GR E + ++ + V +KWK P +GG +T +IVE++ + W+K + T
Sbjct: 18105 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18164
Query: 761 FSTNKVEEGKAYQFRILAVNSEG-VSDPLETE-EVFAGNPIEPPGFASQPQVTDVTKEAV 818
F+ + + E + Y+FR++A N+ G S+P ++ + A + I+ P + P+ DV
Sbjct: 18165 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHA 18224
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLED---TEYEFR 875
T+ G P+ + K G L + I+ T +++D T+
Sbjct: 18225 GETFVLEADIRGKPIPDVVWS--KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 18282
Query: 876 VIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPS 933
++ ++ G G S+P + V P P G L V+ + LAW P + G S
Sbjct: 18283 ILKLSNVG-GTKSIPITVKVLDRPGPPEG---PLKVTGVTAEKCYLAWNPPLQDGGANIS 18338
Query: 934 GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV 993
YI+E R W++ + + Y V L+ +Y FR+ AVN+ G+GEP+E
Sbjct: 18339 HYIIEKRETSRLSWTQVST-EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT 18397
Query: 994 RAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKG 1047
P PP+ P ++SA K MVV + G+ I +K D +
Sbjct: 18398 ACNPYKPPGPPSTP--EVSAITKDSMVVTWARPV----DDGGTEIEGYILEKRDKEGVRW 18451
Query: 1048 RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG---EARYDIHVRVADF---PRPPTN 1101
+ K+ + + S +R+ +N G + + R D P PP+N
Sbjct: 18452 TKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSN 18511
Query: 1102 LRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTAAER--VFSNKYTVT 1157
++ + ++V+L W S + + G Y++ ++A+ W T + ++TVT
Sbjct: 18512 PKVTDTSRSSVSLAW--SKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVT 18569
Query: 1158 GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT 1217
L +Y FR+ A N G EP + ++ +++I+ +L +K V
Sbjct: 18570 KLKENTEYNFRICAINSEGVGEPATLPGS-VVAQERIEPPEIELDADLRK--------VV 18620
Query: 1218 PLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTL 1277
L+ LR + G P P V K + +T ++ TS LVI T
Sbjct: 18621 VLRASATLR-----LFVTIKGRPEPEVKWEKAEGILTDRAQI--EVTSSFTMLVIDNVTR 18673
Query: 1278 KDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
DSG Y++ +EN G + + V D V +I E
Sbjct: 18674 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIRE 18712
Score = 141 bits (356), Expect = 4e-33
Identities = 163/756 (21%), Positives = 295/756 (39%), Gaps = 74/756 (9%)
Query: 581 GKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVT 640
GKYT + S AS+ + P + +T K VP P
Sbjct: 19756 GKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVT-KESAVLSWDVPENDGGAPVKN 19814
Query: 641 WYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG---SATATLHLSV 697
++ + E +++ VS+ ++ ++N + +N+ G A + +
Sbjct: 19815 YHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI 19874
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGK 757
++P PP+ ++ +S V + W P+ +GG + ++VE G+K+W+K K
Sbjct: 19875 TEKPSPPE-KLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA--K 19931
Query: 758 VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGFASQ--PQVTDVT 814
T+ + + E Y FR+ A N G+SDP E V +EPP + P T
Sbjct: 19932 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYV 19991
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE- 873
+ + + P G P+ + R VP+ T+ T + L + +
Sbjct: 19992 RAGSNLKVDIPIS--GKPLPKVTLSRDG------VPLKATMRFNTEITAENLTINLKESV 20043
Query: 874 ------FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPA 927
+ + A N +G + + + VV P P G V +SD + S++L W P
Sbjct: 20044 TADAGRYEITAANSSGTTKAFI--NIVVLDRPGPPTGPVV---ISDITEESVTLKWEPPK 20098
Query: 928 E--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
G + YIL R T W++ + ++ T V L ++Y FRI+A N G+ +
Sbjct: 20099 YDGGSQVTNYILLKRETSTAVWTEVSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISD 20157
Query: 986 PVELDKGVRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDV 1036
++ +P PP+ P R + H V G + + +
Sbjct: 20158 HIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSI 20217
Query: 1037 IWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH---VRVA 1093
+WQK + + ++ + F + + +R+ +N G + V
Sbjct: 20218 LWQK------ANKLVIRT---THFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAI 20268
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSN 1152
D PP N+R+ + N+V+L+W YI+ +RD W A+ V
Sbjct: 20269 DACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTET 20328
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHA 1212
++ ++GL +Y FRV ARN +G I + S + P D
Sbjct: 20329 QFIISGLTQNSQYEFRVFARNAVGS----------------ISNPSEVVGPITCIDSYGG 20372
Query: 1213 PRFVTPLKPHTVLR---GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
P PL+ V++ G + G P PT+ YK D + N+ +T+ + +
Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20432
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
++I +SG Y + + N +G ++ + + DK
Sbjct: 20433 ILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20468
Score = 139 bits (349), Expect = 2e-32
Identities = 190/815 (23%), Positives = 305/815 (37%), Gaps = 84/815 (10%)
Query: 528 GSPAELCVVLNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
G P L ++ V W K G + G Q+ + L+ P+ + GKY+
Sbjct: 12124 GCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG-QVDLVDTMAFLVIPNSTRDDSGKYSLT 12182
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
E +VF+ P + L +T H + P +VT Y +
Sbjct: 12183 LVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSW--APPENDGGSQVTHYI--V 12238
Query: 647 EVTEEERVSMERGEDQALLT---ISNCVREDSGLILLKLKNDHGSATAT------LHLSV 697
E E +R + + T ++N V + + N++G T L
Sbjct: 12239 EKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12298
Query: 698 LDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKS--WIKIGEVD 755
L P PP+ ++E E++ + + W P +GG + +I R + + W + V
Sbjct: 12299 LSEPDPPR-KLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVV- 12356
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF-AGNPIEPPGFASQPQVTDVT 814
K + ++EGK Y+FR+ A N+ GVS P E E V+ A + PP Q+T
Sbjct: 12357 -KDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQIT--I 12413
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEF 874
K + A P + + ++ + V+K D +D+ Y +
Sbjct: 12414 KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY-Y 12472
Query: 875 RVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPP 932
+ A N +G + + A P +PP +SD + SL+W P E G
Sbjct: 12473 SLTAENSSGTDTQKIKVVVMDAPGPPQPP-----FDISDIDADACSLSWHIPLEDGGSNI 12527
Query: 933 SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG 992
+ YI+E +W +C VG LI Q+Y FR+RA N G+ EP+ K
Sbjct: 12528 TNYIVEKCDVSRGDWVTALASVTKTSC-RVGKLIPGQEYIFRVRAENRFGISEPLTSPKM 12586
Query: 993 VRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT 1052
V P F + + K+ V + CI A+ PD G P G
Sbjct: 12587 VAQFP------FGVPSEPKNARVTKVNKD-CIFVAWDR---PD---SDGGSPIIGYLIER 12633
Query: 1053 KSKNH------SQFLINSTKRSDSGV-------YRILLQNEFGEA---RYDIHVRVADFP 1096
K +N + L+ ST+ +G+ +RI N+ G + + +V
Sbjct: 12634 KERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPV 12693
Query: 1097 RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWY---TAAERVFSNK 1153
PP + + +TV+L W Y + W TA ++ +
Sbjct: 12694 DPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEE 12753
Query: 1154 YTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ---DLSAKLKPYEKKDWR 1210
YT TGL +Y FR +AR + S P + D I + + DLS +K
Sbjct: 12754 YTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL----- 12808
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
TV G + + G P PTV+ K + +CTL
Sbjct: 12809 ------------TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTL 12856
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+ + KDSGDY++ EN G ++ L V DK
Sbjct: 12857 ELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 12891
Score = 137 bits (346), Expect = 5e-32
Identities = 219/998 (21%), Positives = 382/998 (38%), Gaps = 131/998 (13%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P K+ W K + I + K V + T LVI N +D+G YSL++ G+K +
Sbjct: 12137 PAPKVTWRK----VGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAV 12192
Query: 318 SAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITV 377
+ VLD P + ++K VT+ V + V + ++ + D K TV
Sbjct: 12193 FVNVRVLDTPGP-VSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTV 12251
Query: 378 SEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRAC 437
+ + + + + + F A N T P+ L + R
Sbjct: 12252 TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSE---PDPPRKL 12308
Query: 438 LECELTSKDVTLRW---KKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQ 494
E+T TL W +DG + G S E + A+ E + + D V ++
Sbjct: 12309 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD-LSLVVTGLK 12367
Query: 495 DGDPTEYYSTA--------------IVTVEERL----------ATVKSGMS---DVHAAT 527
+G ++ A + +E+L T+K+G + H
Sbjct: 12368 EGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAH-VY 12426
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA 587
G P C W K E+ + + K + LI + + G Y+ A
Sbjct: 12427 GKPHPTC----------KWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTA 12476
Query: 588 K---GTESE---ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW 641
+ GT+++ V A P P + + A A ++ + HI + G + +
Sbjct: 12477 ENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL----SWHIPLEDGGSNI--TNY 12530
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG-SATATLHLSVLDR 700
+ +V+ + V+ + + + + ++ +N G S T V
Sbjct: 12531 IVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQF 12590
Query: 701 P-----KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVD 755
P +P RV +++ C+ + W P +GG P+ +++ER+ W+K +
Sbjct: 12591 PFGVPSEPKNARV--TKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTL 12648
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE-TEEVFAGNPIEPPGFASQPQVTDVT 814
+ T + + EG Y FRI A+N G S P + TE V A P++PPG +P+V DVT
Sbjct: 12649 VRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPG---KPEVIDVT 12705
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP--IQGTKCTVDGLLEDTEY 872
K V++ W P DGG+ ++GY VE K + WV N P I + T GL E +Y
Sbjct: 12706 KSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQY 12765
Query: 873 EFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSI------------- 919
+FR IA PS PS V PP + DL V+ S ++
Sbjct: 12766 QFRAIARTAVNISPPSEPSDPVTILAENVPPRI--DLSVAMKSLLTVKAGTNVCLDATVF 12823
Query: 920 -----SLAWR------EPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 968
+++W+ +PAEG + R T E + T
Sbjct: 12824 GKPMPTVSWKKDGTLLKPAEGIK----MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 12879
Query: 969 QKYFFRIRAVNEAGVGEPVELDK--GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHA 1026
+ +++ +++ G V+++K RAM P D + + +++V + T+ A
Sbjct: 12880 KSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWA 12939
Query: 1027 AFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
S + P + + E + + + QF I + + G + + + Y
Sbjct: 12940 QVSATVP---------ITSCSVEKLIEGHEY-QFRICAENKYGVG-DPVFTEPAIAKNPY 12988
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA 1146
D R PP + ++ +T++W D Y++ KR+ W
Sbjct: 12989 DPPGRC----DPPVISNITKD---HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVN 13041
Query: 1147 ER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ + TGL G +Y FRV A N+ G +P D+
Sbjct: 13042 RKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDA 13079
Score = 137 bits (344), Expect = 9e-32
Identities = 160/649 (24%), Positives = 257/649 (39%), Gaps = 75/649 (11%)
Query: 690 TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
T L ++ +DRP P+ + + + V++KW+ P +GG P + VERR G W
Sbjct: 11593 TPILAINPIDRPGEPEN-LHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWE 11651
Query: 750 KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQ 809
++ + K T++ ++ E + Y+FR+ N G SD ++TEEV ++ P +
Sbjct: 11652 RVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLS 11711
Query: 810 VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP-IQGTKCTVDGLLE 868
K TI A + P + + ++ V D +K ++
Sbjct: 11712 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11771
Query: 869 DTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE 928
++ V A N AG V ++V D PG V++L + D S+ ++ W P +
Sbjct: 11772 SDGGKYVVTATNTAGS---FVAYATVNVLDK---PGPVRNLKIVDVSSDRCTVCWDPPED 11825
Query: 929 --GDPPSGYILEMRAEDTKEWSKCTKIPIS-GTCYTVGGLIERQKYFFRIRAVNEAGVGE 985
G YILE WS + ++ GT TV LIE +Y FR+RA N+ G G
Sbjct: 11826 DGGCEIQNYILEKCETKRMVWSTYSATVLTPGT--TVTRLIEGNEYIFRVRAENKIGTGP 11883
Query: 986 PVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPT 1045
P E + P A K+D R V + +PP + DG +
Sbjct: 11884 PTE------SKPVIAKTKYDKPGRPDPPEVTKVSKE---EMTVVWNPP-----EYDGGKS 11929
Query: 1046 KGRETITKSKNHSQFLINSTKRS--------------DSGVYRILLQNEFGEARYDIHVR 1091
+ K + HS + K + +R+ +NE G + R
Sbjct: 11930 ITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR 11989
Query: 1092 VA------DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH---YIIMKR----DAS 1138
+ P PPTN R+ + +++TL W DG A Y++ R DAS
Sbjct: 11990 PVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPV---YDGGAPIIGYVVEMRPKIADAS 12046
Query: 1139 TATWY---TAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ 1195
+ AA ++ ++TVT L ++Y FRV A+N++G P
Sbjct: 12047 PDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP--------------A 12092
Query: 1196 DLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA 1255
+L +KP E + + K V G + G P P VT K ++
Sbjct: 12093 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 12152
Query: 1256 NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
K + + LVIP T DSG YS+ + N G+ + V D
Sbjct: 12153 R-KGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLD 12200
Score = 135 bits (341), Expect = 2e-31
Identities = 152/639 (23%), Positives = 252/639 (39%), Gaps = 77/639 (12%)
Query: 712 ELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKA 771
+++ + + +KW PKDNG P+ + +E+R V W ++ + + + + EG
Sbjct: 8416 DVTSNSMLVKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 8474
Query: 772 YQFRILAVNSEG---VSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQD 828
Y FR+ A N+ G S P + + A +PI PPG P+VTD + + + W P +
Sbjct: 8475 YVFRVCAENAAGPGKFSPPSDPKT--AHDPISPPG-PPIPRVTDTSSTTIELEWEPPAFN 8531
Query: 829 GGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPS 888
GG ++GY V+++ G+N W + I+ + TV + E +Y+ RV AVN AG G P
Sbjct: 8532 GGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPG 8591
Query: 889 VPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWS 948
VA +P +PP + D+ V R PA ++ R TK W+
Sbjct: 8592 ETQPVTVA-EPQEPPAVELDVSVKGGIQIMAGKTLRIPA--------VVTGRPVPTKVWT 8642
Query: 949 KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPP-------AA 1001
K G L + + + +E + + + D G + AA
Sbjct: 8643 K-----------EEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAA 8691
Query: 1002 PK---FDLSARLKSHMVVRAGTALCIHAAFSGSPPPD---------VIWQKDGVPTKGRE 1049
+ FD+ + V +C+ + S P D +I +KD R+
Sbjct: 8692 ARVEVFDVPGPVLDLKPVVTNRKMCL---LNWSDPEDDGGSEITGFIIERKDAKMHTWRQ 8748
Query: 1050 TITKSKNHSQFLINSTKRSDSGVYRILLQNEFG-----EARYDIHVRVADFPRPPTNLRL 1104
I ++ I +R++ +N+FG E + V P P L
Sbjct: 8749 PIETERSKCD--ITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTY 8806
Query: 1105 FEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVF-SNKYTVTGLLPGR 1163
E +T+TL W YII KR + +R+ + + V L +
Sbjct: 8807 TERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQ 8866
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHT 1223
Y FRV A NEIG+SEP S ++ +D + KL+ + D
Sbjct: 8867 MYEFRVKAVNEIGESEP--SLPLNVVIQDDEVPPTIKLRLSVRGD------------TIK 8912
Query: 1224 VLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS------KFWYNSTSGVCTLVIPTCTL 1277
V G+ + G P P + K + I + K + + L IP
Sbjct: 8913 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 8972
Query: 1278 KDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
+D G Y+V N LG + + VYD+ ++T+
Sbjct: 8973 EDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9011
Score = 130 bits (328), Expect = 6e-30
Identities = 143/631 (22%), Positives = 251/631 (39%), Gaps = 64/631 (10%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P G ++++++ + +KW P +GG + + +E+R G + W++ D
Sbjct: 21357 PVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQ-GNERWVRCNFTDVSECQ 21415
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE--VFAGNPIEPPGFASQPQVTD--VTKE 816
++ + G Y+FRI+A N+ G P + + PP P+ D + K
Sbjct: 21416 YTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKS 21475
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
++ A Q P + + + + + + + D + T V D + V
Sbjct: 21476 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTV 21534
Query: 877 IAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGD--PPSG 934
A N +G + + V +D P +V + ++ + ++L W P P +
Sbjct: 21535 EAKNASGSAKAEI---KVKVQDT--PGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITH 21589
Query: 935 YILEMRAEDTKEWS----KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELD 990
YI+E R W+ KC YT LI +Y FR+ AVN+ GVG P++ D
Sbjct: 21590 YIIEKRETSRLAWALIEDKC-----EAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSD 21644
Query: 991 KGVRAMP--PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK-DGVPTKG 1047
V + P AP + + + + + GS I ++ + T+
Sbjct: 21645 PVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR---PESDGGSEIQQYILERREKKSTRW 21701
Query: 1048 RETITKSK-NHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV------ADFPRPPT 1100
+ I+K + ++F + + + ++ +N G R+ + P PPT
Sbjct: 21702 VKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPT 21761
Query: 1101 NLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTA-AERVFSNKYTVT 1157
+++ + TV+L W S V + G YII A W+ AE +YTVT
Sbjct: 21762 VVKVTDTSKTTVSLEW--SKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVT 21819
Query: 1158 GLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ----DLSAKLKPYEKKDWRHAP 1213
L G +Y FRV A N G + + T + D++ D+ A K
Sbjct: 21820 DLQAGEEYKFRVSAINGAGKGDSCEVTGT-IKAVDRLTAPELDIDANFK----------- 21867
Query: 1214 RFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIP 1273
+ H V G + A+ G P PT K D N++ + ++T TL +
Sbjct: 21868 ------QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADI--HTTDSFSTLTVE 21919
Query: 1274 TCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
C D+G Y++ VEN G + T+ V D
Sbjct: 21920 NCNRNDAGKYTLTVENNSGSKSITFTVKVLD 21950
Score = 130 bits (327), Expect = 8e-30
Identities = 192/809 (23%), Positives = 309/809 (38%), Gaps = 115/809 (14%)
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
W K EI D + + + L+ ++ GKYT + + S F+
Sbjct: 16479 WGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDT 16536
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW----YKDGMEVTEEERVSMERGED 661
PS L IT K +TW G ++ E
Sbjct: 16537 PSPPVNLKVTEIT---------------KDSVSITWEPPLLDGGSKIKNYIVEKREATRK 16581
Query: 662 QALLTISNCVRED----------SGLILLKLKNDHG---SATATLHLSVLDRPKPPQGRV 708
++NC + S + +N++G A + V + P+PP G++
Sbjct: 16582 SYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKI 16640
Query: 709 EFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEE 768
+++ + V + W P+ +GG + Q+IVE +A + W + V K + +
Sbjct: 16641 TVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARV--KSLQAVITNLTQ 16698
Query: 769 GKAYQFRILAVNSEGVSDP--LETEEVFAGNPIEP---PGFASQP-QVTDVTKEAV---- 818
G+ Y FR++AVN +G SDP L V IEP P F+S QV K V
Sbjct: 16699 GEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG 16758
Query: 819 ----TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEF 874
TITW T+DG P+ K+ + + V D + T ++ +D ++
Sbjct: 16759 RPKPTITW---TKDG-LPL--------KQTTRINVT---DSLDLTTLSIKETHKDDGGQY 16803
Query: 875 RVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREP--AEGDPP 932
+ N G S+ ++ DP K P + D S SI+L+W P G
Sbjct: 16804 GITVANVVGQKTASIEIVTLDKPDPPKGP-----VKFDDVSAESITLSWNPPLYTGGCQI 16858
Query: 933 SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG 992
+ YI++ R T W ++ T V L +Y FRI A N G +E D
Sbjct: 16859 TNYIVQKRDTTTTVWD-VVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI 16917
Query: 993 VRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGV 1043
V P PP P ++ ++ H V G + I ++W
Sbjct: 16918 VAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW----- 16972
Query: 1044 PTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQN--EFGEARYDIHVRVADFP-RPPT 1100
TK +TI + +QF + + +R+ +N G+A + VA P PP
Sbjct: 16973 -TKVNKTII---HDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG 17028
Query: 1101 NLRLFEEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAA-ERVFSNKYTVT 1157
N +TL W + V + G YI+ KRD W A+ V ++TV+
Sbjct: 17029 TPEPIMVKRNEITLQW--TKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVS 17086
Query: 1158 GLLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
GL ++Y FRV+A+N G S+P DS + KD+++ P D P+F
Sbjct: 17087 GLTEDQRYEFRVIAKNAAGAISKPSDSTGP-ITAKDEVE------LPRISMD----PKFR 17135
Query: 1217 TPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
+ V G+ + G P PT+ +GD I +++ +T L++
Sbjct: 17136 DTI---VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAI 17192
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
D G Y + N G + V D+
Sbjct: 17193 RIDGGQYILRASNVAGSKSFPVNVKVLDR 17221
Score = 130 bits (326), Expect = 1e-29
Identities = 117/443 (26%), Positives = 200/443 (45%), Gaps = 28/443 (6%)
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K+ V I KPL D+ VF+C E+ +P+ K W++ + L + ++ +
Sbjct: 2568 KLTVAGGAISKPLTDQTVAESQEAVFEC--EVANPDSKGEWLRDGKHLPLTNNIRS---E 2622
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G K L+I+ ++D G Y+ V + SA+L V E +K +K + VTE Q AVF
Sbjct: 2623 SDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKV--EAVKIKKTLKNLTVTETQDAVF 2680
Query: 348 EIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+ L+ V W NG L+ ++KY I+V G ++L+IK+ + D + G L
Sbjct: 2681 TVELTHPNVKGVQWIKNGVVLESNEKYAISVK--GTIYSLRIKNCAIVDESVYGFRLGRL 2738
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
A+L ++ + K + K+V E + E ++ V ++W + K+ +
Sbjct: 2739 GASARLHVETV--KIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRL 2796
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
E K +L++++ SD GEYT V Q E + V E L K+ M ++
Sbjct: 2797 VSERKVHKLMLQNISPSDAGEYTAVVGQ----LECKAKLFV---ETLHITKT-MKNIEVP 2848
Query: 527 TGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
A ++ V +WLK+G EI +IV QG +H+LI + E +YTF
Sbjct: 2849 ETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV 2908
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
+ A++ + P + S+L+ + A K T + V + G W K+G+
Sbjct: 2909 CGNDQVSATLTVT--PIMITSMLKDINAEE---KDTITFEVTVNYEG---ISYKWLKNGV 2960
Query: 647 EVTEEERVSMERGEDQALLTISN 669
E+ ++ M + L I N
Sbjct: 2961 EIKSTDKCQMRTKKLTHSLNIRN 2983
Score = 130 bits (326), Expect = 1e-29
Identities = 162/646 (25%), Positives = 269/646 (41%), Gaps = 69/646 (10%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P GR E + ++ + V ++WK P +GG +T +IVE++ + + W+K + T+
Sbjct: 15941 PCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTH 16000
Query: 761 FSTNKVEEGKAYQFRILAVNSEGV-SDPLE-TEEVFAGNPIEPPGFASQPQVTD--VTKE 816
F + E Y+FR++A N+ GV S+P E T + A + ++PP + P+ D V
Sbjct: 16001 FEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHA 16060
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
+ +A P + +I ++ + + + + D + D+
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG---NY 16117
Query: 877 IAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSG 934
I K G+ SV + V P P G V +S + +LAW+ P + G
Sbjct: 16118 ILKAKNVAGERSVTVNVKVLDRPGPPEGPVV---ISGVTAEKCTLAWKPPLQDGGSDIIN 16174
Query: 935 YILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVR 994
YI+E R W+ + +C V L+E +Y FRI AVN+ GVGEP+E + V
Sbjct: 16175 YIVERRETSRLVWTVVDANVQTLSC-KVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVA 16233
Query: 995 AMP--PPAAPKF-DLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI 1051
P P APK +++ K M+V A+ GS + +K + +E I
Sbjct: 16234 KNPFVVPDAPKAPEVTTVTKDSMIVVWERP----ASDGGSEILGYVLEK-----RDKEGI 16284
Query: 1052 TKSKNHSQFLINSTKRSDSGV-------YRILLQNEFG------EARYDIHVRVADFPRP 1098
++ H + LI + +G+ +R+ +N G + Y P P
Sbjct: 16285 RWTRCHKR-LIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGP 16343
Query: 1099 PTNLRLFEEVPNTVTLTWNHSPDVQEDG--EAHYIIMKRDASTATWYTAAERVFSNKYT- 1155
P N ++ + ++V L+W S + + G YI+ K D S W NK
Sbjct: 16344 PNNPKVIDITRSSVFLSW--SKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNI 16401
Query: 1156 -VTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ----DLSAKLKPYEKKDWR 1210
V LL +Y FR+ A N+ G E D +I +++++ DL +L+
Sbjct: 16402 EVEKLLEKHEYNFRICAINKAGVGEHADVPGP-IIVEEKLEAPDIDLDLELRKIINIRAG 16460
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
+ R P+K G P P V K D I + + TS +L
Sbjct: 16461 GSLRLFVPIK-----------------GRPTPEVKWGKVDGEIRDAAII--DVTSSFTSL 16501
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
V+ DSG Y++ +EN G + T+ V D V +TE
Sbjct: 16502 VLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTE 16547
Score = 129 bits (324), Expect = 2e-29
Identities = 180/796 (22%), Positives = 290/796 (36%), Gaps = 82/796 (10%)
Query: 543 EGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPP 602
E W ++ E TD +QI K +L + GKY + + + S F+
Sbjct: 17558 EITWSREEGEFTDK--VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17615
Query: 603 TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQ 662
P + LA + G K + D E T + ++ +
Sbjct: 17616 LDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK-NYVIDKRESTRKAYANVSSKCSK 17674
Query: 663 ALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ--GRVEFLELSGSCVHM 720
+ N + +N+ G + + +PP G+V ++S + +
Sbjct: 17675 TSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASL 17734
Query: 721 KWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN 780
W+ P+ +GG V ++VE + G + W + E KV N + G+ YQFR+ A N
Sbjct: 17735 MWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAE--SKVCNAVVTGLSSGQEYQFRVKAYN 17792
Query: 781 SEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGA------PVL 834
+G SDP G P+ QP ++ + +N + G PV+
Sbjct: 17793 EKGKSDPR-----VLGVPVIAKDLTIQP--------SLKLPFNTYSIQAGEDLKIEIPVI 17839
Query: 835 GYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEY-----------EFRVIAVNKAG 883
G R + + WV + Q T+ V+ T ++ V A N AG
Sbjct: 17840 G-----RPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAG 17894
Query: 884 PGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRA 941
++ S +V + P P G V+ + S + ++W PA G S YI+E R
Sbjct: 17895 TATENL--SVIVLEKPGPPVGPVR---FDEVSADFVVISWEPPAYTGGCQISNYIVEKRD 17949
Query: 942 EDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMP---- 997
T W + ++ T + L +Y FRI A N G P++ + P
Sbjct: 17950 TTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP 18008
Query: 998 -PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT 1052
PP P ++ ++ H V G I ++W K T ++T
Sbjct: 18009 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLN-KTPIQDTKF 18067
Query: 1053 KSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTV 1112
K+ + L K S + I ++ E D PP N V
Sbjct: 18068 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFV-----ARDPCDPPGRPEAIVITRNNV 18122
Query: 1113 TLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVA 1171
TL W YI+ K+D W A+ V ++TV+GL+ ++Y FRV+A
Sbjct: 18123 TLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIA 18182
Query: 1172 RNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDC 1230
RN G+ SEP DS + +D+I +A L P K V G+
Sbjct: 18183 RNAAGNFSEPSDSSGA-ITARDEIDAPNASLDPKYK-------------DVIVVHAGETF 18228
Query: 1231 TMTCAFLGNPRPTVTLYKGDVNITAN-SKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVEN 1289
+ G P P V K + ++ ST TLV+ C D G Y + + N
Sbjct: 18229 VLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSN 18288
Query: 1290 ELGKDRSSCTLTVYDK 1305
G T+ V D+
Sbjct: 18289 VGGTKSIPITVKVLDR 18304
Score = 123 bits (309), Expect = 1e-27
Identities = 159/650 (24%), Positives = 271/650 (41%), Gaps = 64/650 (9%)
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
L + L P P+ R+ + E + S + + WK P+ NGG P+ +I+E+R K + ++
Sbjct: 8790 LAVDPLGPPTSPE-RLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 8848
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVT- 811
+ T+F ++E + Y+FR+ AVN G S+P V + PP + V
Sbjct: 8849 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG 8908
Query: 812 DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP-----VNKDPIQG----TKCT 862
D K + P G P+ +E K + + P + K+ + T+ +
Sbjct: 8909 DTIKVKAGEPVHIPADVTGLPMPK--IEWSKNETVIEKPTDALQITKEEVSRSEAKTELS 8966
Query: 863 VDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ + + + + V A N+ G +V V D PP ++L V+D S L
Sbjct: 8967 IPKAVREDKGTYTVTASNRLGSVFRNV---HVEVYDRPSPP---RNLAVTDIKAESCYLT 9020
Query: 923 WREPAE--GDPPSGYILEMRAEDTK--EWSKCTKIPISGTCYTVGGLIERQKYFFRIRAV 978
W P + G + Y+++ R K EW + T + Y + LI +Y FR+RAV
Sbjct: 9021 WDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKR-YGIWKLIPNGQYEFRVRAV 9079
Query: 979 NEAGVGEPVELDKGVRAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPP 1033
N+ G+ + + DK V P PP PK + AR K M+V L +G P
Sbjct: 9080 NKYGISDECKSDKVVIQDPYRLPGPPGKPK--VLARTKGSMLVSWTPPLD-----NGGSP 9132
Query: 1034 PDVIW---QKDGVP---TKGRETITK-SKNHSQFLINSTKRSDSGVYRILLQNEFG---- 1082
W +++G P R ITK +F + +R + N G
Sbjct: 9133 ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPP 9192
Query: 1083 EARYDIHVRVADF--PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDAS 1138
D V P PP+ + ++ ++++L W P ++ G YI+ ++
Sbjct: 9193 SEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWK--PPAKDGGSPIKGYIVEMQEEG 9250
Query: 1139 TATWYTAAER---VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ 1195
T W E + + + V L RKY FRV A NE G+SEP D+ T I IQ
Sbjct: 9251 TTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDT--TGEIPATDIQ 9308
Query: 1196 DLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTC-AFLGNPRPTVTLYKGDVNIT 1254
+ +D + + ++ V++G+ + F G + + D+
Sbjct: 9309 EEPEVFIDIGAQDCLVC-KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 9367
Query: 1255 ANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
A + NS+ ++IP C +G YS+ +N+ G+ ++C + V D
Sbjct: 9368 AQLETAENSS----VIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMD 9413
Score = 122 bits (307), Expect = 2e-27
Identities = 148/640 (23%), Positives = 248/640 (38%), Gaps = 83/640 (12%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
+RP PP G++ ++++ + V + W+ P+ +GG + +IVE + G W V KV
Sbjct: 15550 ERPLPP-GKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATV--KV 15606
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-EVFAGNPIEPPGF----------ASQ 807
T + + +G+ Y FR+ A N +G+SDP + V A + + PP F A +
Sbjct: 15607 TEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGE 15666
Query: 808 PQVTDVT---KEAVTITW---NAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
DV + +TW N P + E + S L +
Sbjct: 15667 DLKVDVPFIGRPTPAVTWHKDNVPLKQ----TTRVNAESTENNSLLTIK----------- 15711
Query: 862 TVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISL 921
D ED + + V N AG ++ + +V+ D PP + + + + SI+L
Sbjct: 15712 --DACREDVGH-YVVKLTNSAGE---AIETLNVIVLDKPGPP--TGPVKMDEVTADSITL 15763
Query: 922 AWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVN 979
+W P G + YI+E R T W + ++ T L +Y FRI A N
Sbjct: 15764 SWGPPKYDGGSSINNYIVEKRDTSTTTW-QIVSATVARTTIKACRLKTGCEYQFRIAAEN 15822
Query: 980 EAGVGEPVELDKGVRAMP-----PPAAPKFDLSAR----LKSHMVVRAGTALCIHAAFSG 1030
G + + V P PP P LS+R ++ + + G + I
Sbjct: 15823 RYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLER 15882
Query: 1031 SPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYD--I 1088
++W K + I ++K F + +R+ +N G +
Sbjct: 15883 KERNSILWVK-----LNKTPIPQTK----FKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 15933
Query: 1089 HVRVADFP-RPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA- 1146
VA P PP N+VTL W YI+ K++ W A+
Sbjct: 15934 ECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASF 15993
Query: 1147 ERVFSNKYTVTGLLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYE 1205
+ + VTGL+ +Y FRV+ARN G SEP +S + +D++ + P
Sbjct: 15994 TNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA-ITARDEVDPPRISMDPKY 16052
Query: 1206 KKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTS 1265
K V G+ + G P PT+ KGD ++ ++ ST
Sbjct: 16053 KDTI-------------VVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16099
Query: 1266 GVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+L + DSG+Y + +N G+ + + V D+
Sbjct: 16100 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDR 16139
Score = 122 bits (306), Expect = 2e-27
Identities = 200/934 (21%), Positives = 332/934 (35%), Gaps = 131/934 (14%)
Query: 441 ELTSKDVTLRWKK---DGQLLMHGTKYSMNHEGKRA-------------ELIIEDAQLSD 484
+ T K +L W K DG L + G G A + ++ D Q +
Sbjct: 14186 DTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKE 14245
Query: 485 GGEYTVVAMQD---GDPTEYYSTAIVTVE-----------ERLATVKSGMSD--VHAATG 528
+ + A+ D G+P IV E R V++G+S G
Sbjct: 14246 KYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKG 14305
Query: 529 SPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAK 588
PA E W KD + + ++ + + LI P GK+ +
Sbjct: 14306 RPAP----------EVTWTKDNINLKNRANIENTESFTL--LIIPECNRYDTGKFVMTIE 14353
Query: 589 GTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEV 648
+ S F+ P + L IT K T H +P G +
Sbjct: 14354 NPAGKKSGFVNVRVLDTPGPVLNLRPTDIT-KDSVTLHWDLPL----------IDGGSRI 14402
Query: 649 TE---EERVSMERGEDQALLTISNCVREDSGL-------ILLKLKNDHG---SATATLHL 695
T E+R + + A C + +GL + +N++G T +
Sbjct: 14403 TNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPV 14462
Query: 696 SVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVD 755
+ P PP + ++++ S V + W PK +GG +T +++E + G W I V
Sbjct: 14463 KASEAPSPPDS-LNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVK 14521
Query: 756 GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQP--QVTDV 813
G + EG+ Y F+++AVNS G S P E+ V P + Q +
Sbjct: 14522 G--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14579
Query: 814 TKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCT----VDGLLED 869
K I P P + + KKG + + + T + ++ +
Sbjct: 14580 AKAGDNIKVEIPVLGRPKPTVTW-----KKGDQILKQTQRVNFETTATSTILNINECVRS 14634
Query: 870 TEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE- 928
+ + A N G + ++ D PP + + S+ ++ +W P
Sbjct: 14635 DSGPYPLTARNIVGEVGDVI---TIQVHDIPGPP--TGPIKFDEVSSDFVTFSWDPPEND 14689
Query: 929 -GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPV 987
G P S Y++EMR D+ W + I T Y L +Y FR++A N GVG +
Sbjct: 14690 GGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRYGVGPGI 14748
Query: 988 ELDKGVRAMP-----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG 1042
V P PP P+ ++A K M + H S P + + +
Sbjct: 14749 TSACIVANYPFKVPGPPGTPQ--VTAVTKDSMTISW------HEPLSDGGSPILGYHVER 14800
Query: 1043 VPTKGRETITKSKNHSQFLINSTKRSDSGV---YRILLQNEFGEARYD------IHVRVA 1093
G T SK I + G+ +R++ +N G+++ + +
Sbjct: 14801 KERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPI 14860
Query: 1094 DFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA-ERVFSN 1152
D P P L + +TVTL W YI+ KRD W A + N
Sbjct: 14861 DPPGKPVPLNITR---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILEN 14917
Query: 1153 KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHA 1212
++TV+GL Y FRV+A+N G P + +D ++ + K+K K
Sbjct: 14918 EFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVE--APKIKVDVK------ 14969
Query: 1213 PRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLV 1271
K +L+ G+ + G P PT+ K + +K LV
Sbjct: 14970 ------FKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLV 15023
Query: 1272 IPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
T +DSG Y++ N G + + V D+
Sbjct: 15024 NKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDR 15057
Score = 121 bits (303), Expect = 5e-27
Identities = 146/660 (22%), Positives = 265/660 (40%), Gaps = 56/660 (8%)
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLE 128
F ++ Q V A E D + W ++ G+ + E K S K H L +
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKD-GMEVHEGDKYRMHSDRKVHFLSIL 2188
Query: 129 PLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANE 188
+ + D+++Y C+ D + + T + L+ EG ++F K L+ P + +
Sbjct: 2189 TIDTSDAEDYSCVLVED--ENVKTTAKLIVEG-AVVEFVKELQDIEVPESYSGELECIVS 2245
Query: 189 KEMLEILSKVPKKDFE-KVCMEYGFTDFRG--------------------LLRKLKEMKK 227
E +E K D E K +Y T RG + K K
Sbjct: 2246 PENIE--GKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2303
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K++ I IL+ L D++ V + + L+ +V+ +W+K + ++ + K
Sbjct: 2304 KMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE--SVEGVWMKDGQEVQPSDRVHIVIDK 2361
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
Q +ML+I ++ DAG YS ++ +S V + + +K V V E AV
Sbjct: 2362 Q---SHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVL 2418
Query: 348 EIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
E ++S + V W N +++K DD+ + V G L I SD G + G +
Sbjct: 2419 ECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK--GTKQRLVINRTHASDEGPYKLIVGRV 2476
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
L++++ IK + L+++ E E EL+ + + W + + +KY +
Sbjct: 2477 ETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKI 2534
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
GK +L + + D G+YT A E ++ +TV + ++D A
Sbjct: 2535 EAHGKIYKLTVLNMMKDDEGKYTFYA------GENMTSGKLTVAG--GAISKPLTDQTVA 2586
Query: 527 TGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A C V N + +G WL+DGK + ++ G +LI + + G+YT+
Sbjct: 2587 ESQEAVFECEVANPDS-KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTY 2645
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+ +++ A + + +V +TV A V + V W K+G
Sbjct: 2646 KVATSKTSAKLKV-------EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNG 2698
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
+ + E+ ++ L I NC D + +L A+A LH+ + K P+
Sbjct: 2699 VVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL--GRLGASARLHVETVKIIKKPK 2756
Score = 121 bits (303), Expect = 5e-27
Identities = 150/654 (22%), Positives = 261/654 (39%), Gaps = 83/654 (12%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P G+ E ++++ S V + W PK +GG + + VE + W++ ++
Sbjct: 12692 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12751
Query: 761 --FSTNKVEEGKAYQFRILAVNSEGVSDPLETEE---VFAGNPIEPPGFASQPQVTDVTK 815
++ +EE YQFR +A + +S P E + + A N + + K
Sbjct: 12752 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVK 12811
Query: 816 EAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN--KDPIQGTKCTVD--GLLEDTE 871
+ +A P + + KK L P K +Q CT++ +
Sbjct: 12812 AGTNVCLDATVFGKPMPTVSW-----KKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12866
Query: 872 YEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--G 929
++ + A N +G S+ + + PG + ++ + L+W P E G
Sbjct: 12867 GDYTITAENSSGS------KSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGG 12920
Query: 930 DPPSGYILEMRAEDTKEWSKCTK-IPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE 988
+ YI++ R W++ + +PI T +V LIE +Y FRI A N+ GVG+PV
Sbjct: 12921 SEITNYIVDKRETSRPNWAQVSATVPI--TSCSVEKLIEGHEYQFRICAENKYGVGDPVF 12978
Query: 989 LDKGVRAMPPPAAPKFD---LSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPT 1045
+ + P + D +S K HM V S PP D G P
Sbjct: 12979 TEPAIAKNPYDPPGRCDPPVISNITKDHMTV------------SWKPPAD----DGGSPI 13022
Query: 1046 KG-----RET--ITKSKNHSQFLINSTKRSDSGV-------YRILLQNEFG-----EARY 1086
G RET + +K + + +I T ++ +G+ +R+ N+ G +A
Sbjct: 13023 TGYLLEKRETQAVNWTKVNRKPIIERTLKA-TGLQEGTEYEFRVTAINKAGPGKPSDASK 13081
Query: 1087 DIHVRVADFPR-PPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTA 1145
+ R +P PP ++++ ++V+L+W Y++ + A + W
Sbjct: 13082 AAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRC 13141
Query: 1146 --AERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203
+ + ++ VTGL+ +Y FRV A N+IG S+P D D K +D+ + P
Sbjct: 13142 NLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPD-----KHYPKDIL--IPP 13194
Query: 1204 YEKKDWRHAPRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
+ D L+ +LR G + G P P +T K +VN+
Sbjct: 13195 EGELD--------ADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIK 13246
Query: 1263 STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
ST L D+G Y + +EN GK + + V D V ++ E
Sbjct: 13247 STDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKE 13300
Score = 121 bits (303), Expect = 5e-27
Identities = 140/627 (22%), Positives = 244/627 (38%), Gaps = 83/627 (13%)
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRIL 777
V + W P +GG +T+++VER+ G+++W G K ++++E +FR+
Sbjct: 20982 VILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGI--SKTCEIEVSQLKEQSVLEFRVF 21039
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTIT------WNAPTQDGGA 831
A N +G+SDP+ + I P + ++D+ VT+ P +
Sbjct: 21040 AKNEKGLSDPVTIGPITVKELIITP----EVDLSDIPGAQVTVRIGHNVHLELPYKGKPK 21095
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
P + ++ + + +V +K + T ++ ++ ++ VI N + +VP
Sbjct: 21096 PSISWLKDGLPLKESEFVRFSKTENKIT-LSIKNAKKEHGGKYTVILDNAVC--RIAVPI 21152
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSK 949
+ + P KP G ++ + S+ L+W P + G + Y +E R W K
Sbjct: 21153 TVITLGPPSKPKGPIR---FDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW-K 21208
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEP-----VELDKGVRAMPPPAAPKF 1004
++ T + V L++ +Y FR+RA N GV +P + R PP P
Sbjct: 21209 MVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVI 21268
Query: 1005 DLSARLKSHMVVRAGTALCIHA-AFSGSPPP-----------DVIWQKDGV-PTKGRETI 1051
+ V G +L A + G ++WQK P GRE
Sbjct: 21269 --------YNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGRE-- 21318
Query: 1052 TKSKNHSQFLINSTKRSDSGVYRILLQNEFG------EARYDIHVRVADFPRPPTNLRLF 1105
+ +R+ +N G +++ + V D P P + +
Sbjct: 21319 --------YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVT 21370
Query: 1106 EEVPNTVTLTWNHSPDVQEDGE--AHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGR 1163
E T+TL WN P +++ G Y I KR + V +YTVTGL PG
Sbjct: 21371 RE---TITLKWN--PPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGD 21425
Query: 1164 KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHT 1223
+Y FR++ARN +G P ++ +D+ + P + P + L
Sbjct: 21426 RYEFRIIARNAVGTISPPSQSSGIIMTRDE------NVPPIVE----FGPEYFDGL---I 21472
Query: 1224 VLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDY 1283
+ G+ + G P P VT +K V I G +L + T G Y
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21532
Query: 1284 SVLVENELGKDRSSCTLTVYDKDDKSV 1310
+V +N G ++ + V D K V
Sbjct: 21533 TVEAKNASGSAKAEIKVKVQDTPGKVV 21559
Score = 120 bits (302), Expect = 7e-27
Identities = 163/681 (23%), Positives = 272/681 (39%), Gaps = 74/681 (10%)
Query: 361 KFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIK 420
+ N EL R + + +G + +IK A + GE A +++ K L + +
Sbjct: 11355 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 11414
Query: 421 FVS-NLKNVRVKERSRACLECE-LTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIE 478
++ VRV + R + D+T W K+G++L+ + + + R EL I+
Sbjct: 11415 VTCRDVITVRVGQTIRILARVKGRPEPDIT--WTKEGKVLVREKRVDLIQDLPRVELQIK 11472
Query: 479 DAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLN 538
+A +D G+Y + A + +AIV V +R G T E C +
Sbjct: 11473 EAVRADHGKYIISAKNSSGHAQ--GSAIVNVLDR-----PGPCQNLKVTNVTKENCTISW 11525
Query: 539 DEKVEGVWLKDGKEITDL---------PGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKG 589
+ ++ G EIT+ G IV +LI ++ +E Y FR
Sbjct: 11526 ENPLD----NGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNE--YYFRV-C 11578
Query: 590 TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYK---DGM 646
E++ V PTI+ LA + I + G ++ + +GK + W + DG
Sbjct: 11579 AENKVGV----GPTIETKT-PILAINPID-RPGEPENLHIADKGKTFVYLKWRRPDYDGG 11632
Query: 647 EVTEEERVSME-RGED-----------QALLTISNCVREDSGLILLKLKNDHGSATATLH 694
V +G D + + CV ++ KN+ G +
Sbjct: 11633 SPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKT 11692
Query: 695 LSVL---DRPKPPQGRVEFLELSGSCV-----HMKWKAPKDNGGRPVTQFIVERRA--VG 744
V+ D KP V L+LSG ++ +A P + ++ A +
Sbjct: 11693 EEVVVKEDLQKP----VLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11748
Query: 745 KKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGF 804
+ +KI + + FS K + ++ + A N+ G T N ++ PG
Sbjct: 11749 RSPRVKI-DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATV-----NVLDKPGP 11802
Query: 805 ASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPI-QGTKCTV 863
++ DV+ + T+ W+ P DGG + YI+E+ + +W + + GT TV
Sbjct: 11803 VRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGT--TV 11860
Query: 864 DGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAW 923
L+E EY FRV A NK G G P+ S V+AK PG V+ S +++ W
Sbjct: 11861 TRLIEGNEYIFRVRAENKIGTGPPT-ESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVW 11919
Query: 924 REPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEA 981
P G +GY LE + + + W K I V L+ +Y FR++A NE
Sbjct: 11920 NPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEI 11979
Query: 982 GVGEPVELDKGVRAMPPPAAP 1002
G+GEP + V A P P
Sbjct: 11980 GIGEPSLPSRPVVAKDPIEPP 12000
Score = 117 bits (294), Expect = 6e-26
Identities = 148/628 (23%), Positives = 233/628 (37%), Gaps = 87/628 (13%)
Query: 713 LSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAY 772
+S S + WK P +GG + ++V+ K W ++ + +S + EGK Y
Sbjct: 13398 VSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRV--MKSLSLQYSAKDLTEGKEY 13454
Query: 773 QFRILAVNSEGVSDPLETEEVFAGNPIEPP-GFASQPQVTDVTKEAVTITWNAPTQDGGA 831
FR+ A N G P E V + + P P + + KE P + A
Sbjct: 13455 TFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPA 13514
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
P + + ++ V V + T D D ++ + N AG + ++ S
Sbjct: 13515 PSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAG-KYTITLKNVAGTKEGTI-S 13572
Query: 892 SSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSK 949
VV K P P G ++ + + +++L W P + G + YILE R +W
Sbjct: 13573 IKVVGK-PGIPTGPIK---FDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13628
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSAR 1009
C + T + V L E +Y FR+ A N+ GVGE G+++ P A FD+
Sbjct: 13629 CASA-VQKTTFRVTRLHEGMEYTFRVSAENKYGVGE------GLKSEPIVARHPFDVP-- 13679
Query: 1010 LKSHMVVRAGTALCIHAAFSGSPPPDVI----------W----QKDGVPTKGRETITKSK 1055
PPP+++ W + G P G K +
Sbjct: 13680 -------------------DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKER 13720
Query: 1056 NH-------------SQFLINSTKRSDSGVYRILLQNEFGEARYDIH---VRVADFPRPP 1099
N F + +R++ N G + + V D PP
Sbjct: 13721 NSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13780
Query: 1100 TNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAE-RVFSNKYTVTG 1158
+ N+VTL W YI+ KRD + +W A V +TVT
Sbjct: 13781 GKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTD 13840
Query: 1159 LLPGRKYYFRVVARNEIGD-SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVT 1217
L+ G KY FR+ A+N G S P +S +T +I KD+ + + L P K
Sbjct: 13841 LVEGGKYEFRIRAKNTAGAISAPSESTET-IICKDEYEAPTIVLDPTIKDGL-------- 13891
Query: 1218 PLKPHTVLRGQDCTMTC-AFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCT 1276
T+ G + + LG P P + K +I + ST L I T
Sbjct: 13892 -----TIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 13946
Query: 1277 LKDSGDYSVLVENELGKDRSSCTLTVYD 1304
KD+G+Y++ N G +TV D
Sbjct: 13947 RKDAGEYTITATNPFGTKVEHVKVTVLD 13974
Score = 109 bits (273), Expect = 2e-23
Identities = 145/639 (22%), Positives = 241/639 (37%), Gaps = 71/639 (11%)
Query: 695 LSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEV 754
++V +RP+ +E E++ + V + W PK +GG + +++E R +G + + K+
Sbjct: 10217 ITVPERPED----LEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTND 10272
Query: 755 DGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVT 814
+ ++ ++EG Y++R+ AVN G P F PI + P +
Sbjct: 10273 NLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPS-----FCTKPITCKDELAPPTLHLDF 10327
Query: 815 KEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE- 873
++ +TI + G A L + K W D ++ + + E
Sbjct: 10328 RDKLTI------RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEK 10381
Query: 874 ----------FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAW 923
+ V+ N G + + V D PP V + + + + ++W
Sbjct: 10382 IKAKRSDSGKYCVVVENSTGSRKGFCQVNVV---DRPGPP--VGPVSFDEVTKDYMVISW 10436
Query: 924 REPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEA 981
+ P + G + YI+E + W T TC V L+E + Y FRI A N
Sbjct: 10437 KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTC-KVSKLLEGKDYIFRIHAENLY 10495
Query: 982 GVGEPVELD--KGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQ 1039
G+ +P+ D K P AP + + + G P + I +
Sbjct: 10496 GISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNK----PHDGGKPITNYILE 10551
Query: 1040 KDGVPTKGRETITKSKNH--SQFLINSTKRSDSGVYRILLQNEFG------EARYDIHVR 1091
K +K +TK H ++F + +R+ +NE G ++
Sbjct: 10552 KRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKD 10611
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDASTATWYTA---A 1146
P PP N + N+V LTW P + G YI+ + W A
Sbjct: 10612 PIAKPSPPVNPEAIDTTCNSVDLTWQ--PPRHDGGSKILGYIVEYQKVGDEEWRRANHTP 10669
Query: 1147 ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEK 1206
E KY VTGL G+ Y FRV+A N G+S+P + L+ KD+++ L
Sbjct: 10670 ESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLV-KDRLEPPELILD---- 10724
Query: 1207 KDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG 1266
+ + G ++ G P P VT K D + A +K + T
Sbjct: 10725 ---------ANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD--APTKARIDVTPV 10773
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
L I +D G YS+ VEN G S + V DK
Sbjct: 10774 GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 10812
Score = 107 bits (268), Expect = 6e-23
Identities = 144/617 (23%), Positives = 249/617 (40%), Gaps = 55/617 (8%)
Query: 217 GLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLR 276
G K K VE +R +K LE++ T V ++ K+ +V +W K +
Sbjct: 4698 GNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDV--VWRKDGKI-- 4753
Query: 277 IQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV---GDKRMSAELTVLDEPLKFLGE 333
+ G+ +G L I++ + DAG Y+++V + S+ + V++ +L
Sbjct: 4754 VVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWL-- 4811
Query: 334 MKPVK---VTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKD 390
+KP++ V + TA+F ++K PN W E+ + + + DG LKIK+
Sbjct: 4812 VKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKN 4871
Query: 391 ARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLR 450
A D E++ E A+LT+ ++ + +++V + E+ A + E++ D+ +
Sbjct: 4872 AMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQ 4931
Query: 451 WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVE 510
WK G+LL + EG + L + +L GE A+ +TAI+TV+
Sbjct: 4932 WKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQAL------NAITTAILTVK 4985
Query: 511 ERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHK 569
E + DV A CV+ + V +W K I I+ G H
Sbjct: 4986 EIELDFAVPLKDVTVPERRQARFECVLTREANV--IWSKGPDIIKSSDKFDIIADGKKHI 5043
Query: 570 LIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKV 629
L+ + EG YT +G ++ A +F+ S LE TVK G TA
Sbjct: 5044 LVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRLKFMSPLEDQ-----TVKEGETATFVC 5098
Query: 630 PFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA 689
+ + V W+K+ ++ V + L + +D I ++K
Sbjct: 5099 ELSHEKM-HVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVK----EL 5153
Query: 690 TATLHLSVLDRPK------PPQGRVEFLELSGSC-----VHMKWKAPKDNGGRPVTQFIV 738
++T L VL+ + VE E++ C V +KW +G V
Sbjct: 5154 SSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKW---FKDGEEIVPSPKY 5210
Query: 739 ERRAVGKKSWIKIGEVDGK-----VTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEV 793
+A G + +KI + D K V + T+K + + R++ V PL EV
Sbjct: 5211 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEK-----PLYGVEV 5265
Query: 794 FAGNPIEPPGFASQPQV 810
F G S+P V
Sbjct: 5266 FVGETAHFEIELSEPDV 5282
Score = 107 bits (266), Expect = 1e-22
Identities = 168/748 (22%), Positives = 293/748 (39%), Gaps = 96/748 (12%)
Query: 232 EAIRILKPLEDKETKVDTTVVFDC-IMELKDPNVKMIWIK-GTEPLRIQYSLGKYDVKQM 289
EA I K ++D TK+ C I+ P++K W + G E ++ + KY +
Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIK--WYRFGKELIQSR----KYKMSSD 24087
Query: 290 GTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTA 345
G + L + D G+Y+ VG+ S++L + P G P+K
Sbjct: 24088 GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGY--PLKEKYYGAV 24145
Query: 346 VFEIRL-----SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFS 400
+RL + P W F+G++L ++ + + + TH + R + +G++
Sbjct: 24146 GSTLRLHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYK 24204
Query: 401 AEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMH 460
+ N+ +D +++ K +E L + V + WK
Sbjct: 24205 VQLSNVFGTVDAILD-------VEIQDKPDKPTGPIVIEALLKNSAV-ISWKPPAD---D 24253
Query: 461 GTKYSMNH--------EGKRAELIIEDAQLS---------DGGEYTVVAMQD----GDPT 499
G + N+ EG +L+ ++ + G Y V+ Q+ DP
Sbjct: 24254 GGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPL 24313
Query: 500 EYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVL-------NDEKVEGVWLKDGKE 552
E S I+ + K G T + CVV K+ +L+ +E
Sbjct: 24314 EVSSVVII----KSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEK-RE 24368
Query: 553 ITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAK----GTESEASVFI------ADPP 602
+ + + + + +F +Y FR K G ESE S +D P
Sbjct: 24369 KKQNKWISVTTE-EIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVP 24427
Query: 603 TIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEE---RVSMERG 659
P E L + V+ A + G P P V WY+ G E+ + R+ +G
Sbjct: 24428 IQAPHFKEEL--RNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKG 24485
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV-----LDRPKPPQGRVEFLELS 714
L+ I++ +D+ + ++ N GS + T L V + PK +G L
Sbjct: 24486 GYHQLI-IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALR 24544
Query: 715 GSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQF 774
G V +K P PV + + + ++ + N VE A +
Sbjct: 24545 GEVVSIK--IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFY 24602
Query: 775 RILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVL 834
+ A N G+ +T E+ + +PP +V+DV++++V +TW P DGG+ +
Sbjct: 24603 VVCAKNRFGIDQ--KTVELDVADVPDPPRGV---KVSDVSRDSVNLTWTEPASDGGSKIT 24657
Query: 835 GYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSV 894
YIVE+ + W+ V + + T+ TV L T Y+FRVIA NK G +PS PS
Sbjct: 24658 NYIVEKCATTAERWLRVGQ--ARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPT 24715
Query: 895 VAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ K+ K + D V ++ S++ A
Sbjct: 24716 ITKED-KTRAMNYDEEVDETREVSMTKA 24742
Score = 98.2 bits (243), Expect = 5e-20
Identities = 145/714 (20%), Positives = 274/714 (38%), Gaps = 108/714 (15%)
Query: 3 TIHSRQMLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPA 62
T+ + L VS EF TT V T K EE +S +V + +T P
Sbjct: 977 TVSTSCYLAVQVSEEFEKETTAV-----TEKFTTEEKRFVESRDVVMTDTSLTEEQAGPG 1031
Query: 63 GDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA--KIFYDSIN 120
+ P F+ KP EG VF +V GN KPH+ WK+ SG+P+ K+ Y+
Sbjct: 1032 EPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK-SGVPLTTGYRYKVSYNKQT 1090
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK 180
E L + +DD+ Y + N H + + SLL E+ D++ ++K + +
Sbjct: 1091 GECKLVISMTFADDAGEYTIVVRNKHGETSASASLL-----EEADYELLMKSQQEMLYQT 1145
Query: 181 KQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPL 240
+ E ++ E ++EK EY ++ ++KK+ + + + +
Sbjct: 1146 QVTAFVQEPKVGETAPGFVYSEYEK---EYE--------KEQALIRKKMAKDTVVVRTYV 1194
Query: 241 EDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNV 300
ED+E + + ++ +K I+Y + K ++++
Sbjct: 1195 EDQEFHISS---------FEERLIK----------EIEYRIIKTTLEEL----------- 1224
Query: 301 NMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKE-PNFV 359
+ + G ++V A + D +K ++ E F ++S P
Sbjct: 1225 -LEEDGEEKMAVDISESEAVESGFDS------RIKNYRILEGMGVTFHCKMSGYPLPKIA 1277
Query: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQLTID 415
W +GK +K ++Y++ +DG +L+I D G ++A A GN + +L ++
Sbjct: 1278 WYKDGKRIKHGERYQMDFLQDGRA-SLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Query: 416 -RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAE 474
P+ + + + R R+ ++ + + + M + S
Sbjct: 1337 PAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMS--------- 1387
Query: 475 LIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH--AATGSPAE 532
A++S G +++ D ++ ERL + V G A
Sbjct: 1388 ----PARMSPGRR-----LEETDESQL---------ERLYKPVFVLKPVSFKCLEGQTAR 1429
Query: 533 LCV-VLNDEKVEGVWLKDGKEIT-DLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
+ V+ E W DG++I D ++K+ LI P G++T A+
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489
Query: 591 ESEASVFI-----ADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+S+ + A + P +E L + +K G +KV G P P + W K+
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKN--VNIKEGSRLEMKVRATGNPNPDIVWLKNS 1547
Query: 646 MEVTEEE--RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
+ + ++ +E + +A L I + V +DS N G T ++V
Sbjct: 1548 DIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1601
Score = 95.9 bits (237), Expect = 2e-19
Identities = 152/639 (23%), Positives = 238/639 (37%), Gaps = 111/639 (17%)
Query: 430 VKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
VK + CL+ + K + T+ WKKDG LL M + L + D G+Y
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCV-VLNDEKVEGVW- 546
T+ TA + + AT+K + D G PA + + + ++ W
Sbjct: 12870 TI-------------TAENSSGSKSATIKLKVLD---KPGPPASVKINKMYSDRAMLSWE 12913
Query: 547 --LKDG----------KEITDLPGMQIVKQG------AVHKLIFPSMGPEHEGKYTFRAK 588
L+DG K T P V +V KLI HE ++ A+
Sbjct: 12914 PPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLI-----EGHEYQFRICAE 12968
Query: 589 G---------TESEASVFIADPP-TIDPSVLEALAAHAITVKVGHTAHIK-VPFRGKPLP 637
TE + DPP DP V+ + +TV A P G L
Sbjct: 12969 NKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLE 13028
Query: 638 K-----VTWYKDGMEVTEEERVS----MERGEDQALLTISNCVREDSGLILLKLKNDHGS 688
K V W K + E + E E + +T N K G
Sbjct: 13029 KRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAIN-------------KAGPGK 13075
Query: 689 ATATLHLSVLDRPKPPQGRVEF---LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGK 745
+ + P+ P G F + + S V + W P +GG P+ ++VE +
Sbjct: 13076 PSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS 13135
Query: 746 KSWIKIGEVDG-KVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLET-EEVFAGNPIEPPG 803
+W++ + T F + E YQFR+ AVN G SDP + ++ + + + PP
Sbjct: 13136 DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPE 13195
Query: 804 --FASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC 861
+ + T + + VT+ P + P + + K NL + D
Sbjct: 13196 GELDADLRKTLILRAGVTMRLYVPVKGRPPPKITW----SKPNVNLRDRIGLD------- 13244
Query: 862 TVDGLLEDTEYE--FRVIAVNKAGPGQPSVPSSSVVAKDP-------VKPPGLVQDLHVS 912
++ T+++ R VNK G+ + + K + PG ++ V
Sbjct: 13245 -----IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVK 13299
Query: 913 DSSNSSISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQK 970
+ S S + W P G P Y+++ R + K WS T S T + V L E +
Sbjct: 13300 EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTT-ECSKTSFRVANLEEGKS 13358
Query: 971 YFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSAR 1009
YFFR+ A NE G+G+P E V+A P P DL R
Sbjct: 13359 YFFRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVR 13396
Score = 92.8 bits (229), Expect = 2e-18
Identities = 110/495 (22%), Positives = 193/495 (38%), Gaps = 34/495 (6%)
Query: 232 EAIRILKPLEDKETKV-DTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
+ I + L+D K DT F+C E +P VK+ W K + + KY +
Sbjct: 2126 QLITFTQELQDVVAKEKDTMATFEC--ETSEPFVKVKWYKDGMEV---HEGDKYRMHSDR 2180
Query: 291 TKYMLVISNVNMNDAGIYS-LSVGDKRM--SAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+ L I ++ +DA YS + V D+ + +A+L V ++F+ E++ ++V E +
Sbjct: 2181 KVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGEL 2240
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E +S + W N ELK + KY IT S G L +KD D GE+S
Sbjct: 2241 ECIVSPENIEGKWYHNDVELKSNGKYTIT-SRRG-RQNLTVKDVTKEDQGEYSFVIDGKK 2298
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
+L + PI + L + +V E LE +++ + V W KDGQ + + +
Sbjct: 2299 TTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIV 2358
Query: 468 HEGKRAELIIEDAQLSDGGEYT----VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
+ + L+IED D G Y+ + + YS ++T + DV
Sbjct: 2359 IDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVIT----------PLKDV 2408
Query: 524 HAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGK 582
+ G+ A L C V + W + ++I +Q + +G +L+ EG
Sbjct: 2409 NVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGP 2468
Query: 583 YTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWY 642
Y E+ ++ + ++ L T +++ G V W
Sbjct: 2469 YKLIVGRVETNCNLSVE-----KIKIIRGLRDLTCTETQNVVFEVELSHSG---IDVLWN 2520
Query: 643 KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPK 702
E+ + +E LT+ N +++D G + S T+ + +P
Sbjct: 2521 FKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAISKPL 2580
Query: 703 PPQGRVEFLELSGSC 717
Q E E C
Sbjct: 2581 TDQTVAESQEAVFEC 2595
Score = 88.2 bits (217), Expect = 5e-17
Identities = 139/589 (23%), Positives = 233/589 (39%), Gaps = 79/589 (13%)
Query: 65 SVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV 124
+ P K +P+ G A F +Q W + +G I ES K S +++
Sbjct: 4335 AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFK-AGREIYESDKCSIRS--SKYI 4391
Query: 125 LKLEPLTSD--DSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPA----- 177
LE L + D Y C ASN++ T +L VT + +K+L +R P
Sbjct: 4392 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV 4451
Query: 178 --------PKKKQKKVANEKEMLEILSK--VPKKDFEKVCMEYGFTDFRGLLRKLKEMKK 227
P++++ KV E + LE + K VP+ K E RK+ E K
Sbjct: 4452 LKSVLRKRPEEEEPKV--EPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK 4509
Query: 228 KVEVEA----------------IRILKP--LEDKETKVDTTVVFDCI---MELKDPNVKM 266
E++ ++ +KP +E + T + V + E K P +
Sbjct: 4510 VPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEA 4569
Query: 267 IWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMS-AELT--V 323
KG +K + K S + + S G+K A T +
Sbjct: 4570 AKPKGP-------------IKGVPKK---TPSPIEAERRKLRPGSGGEKPPDEAPFTYQL 4613
Query: 324 LDEPLKFLGEMKPVKVTERQ----TAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSE 379
PLKF+ E+K + +TE + +A+FE +S W +G ++ K+
Sbjct: 4614 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIA-- 4671
Query: 380 DGLTHTLKIKDARLSDSGEFSA--EAGN--LVQKAQLTIDRIPIKFVSNL-KNVRVKERS 434
DG L I D +LSD+GE++ GN A+L ++ +P++FV L + V V +
Sbjct: 4672 DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQ 4731
Query: 435 RACLECELTSKDVTLRWKKDGQLLMHGT-KYSMNHEGKRAELIIEDAQLSDGGEYTVVAM 493
L CEL +K+ + W+KDG++++ + G L I DA +D G YT V +
Sbjct: 4732 PLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYT-VTV 4789
Query: 494 QDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEI 553
++ + E S+ + VE + + D H A + + W K EI
Sbjct: 4790 ENANNLE-CSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEI 4848
Query: 554 TDLPG--MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIAD 600
P +I++ G L + PE +Y +G A + + +
Sbjct: 4849 PAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGE 4897
Score = 85.9 bits (211), Expect = 2e-16
Identities = 147/715 (20%), Positives = 268/715 (37%), Gaps = 124/715 (17%)
Query: 72 KPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLT 131
KP+ +T EG+ A F G P ++W R+ + + SA+ + + ++ +
Sbjct: 26069 KPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQV-LSTSARHQVTTTKYKSTFEISSVQ 26127
Query: 132 SDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKR--------APPAPKKKQK 183
+ D NY + N +EG+++ +F ++K +PP K +
Sbjct: 26128 ASDEGNYSVVVEN-------------SEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEP 26174
Query: 184 KVANEKEMLEILS-KVPKKDFEKVCMEYGFTDFRGL-LRKLKEMKKKVEVEAIRILKPLE 241
+V + + + K P+ K T+ + K++ + + + LK
Sbjct: 26175 RVKSPEAVKSPKRVKSPEPSHPKAVSP---TETKPTPTEKVQHLPVSAPPKITQFLKAEA 26231
Query: 242 DKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVN 301
KE T VV ++ K+ + W K + L+ + ++ GT Y L I+N+
Sbjct: 26232 SKEIAKLTCVVESSVLRAKE----VTWYKDGKKLK-ENGHFQFHYSADGT-YELKINNLT 26285
Query: 302 MNDAGIYSLSVGDKRMSAE--LTVLDEPLKFLGEM------------------------- 334
+D G Y + + +++ L + + K + E
Sbjct: 26286 ESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEP 26345
Query: 335 --------KPVKVTERQ--------TAVFEIRLS-KKEPNFVWKFNGKELKRDDKYEITV 377
KPV VT Q A F ++ + + P +W +GK + + KY++
Sbjct: 26346 KAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL-- 26403
Query: 378 SEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTIDRIP---IKFVSNLKNVRV 430
SED L+I SDSG ++ AG++ +LTI I + VS K +
Sbjct: 26404 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEI 26463
Query: 431 KERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTV 490
+ +A ++ E++ K + K + K ++ E + LI E+ + S
Sbjct: 26464 TPQKKAVVQEEISQKALRSEEIKMSEAKSQ-EKLALKEEASKV-LISEEVKKSAATSLEK 26521
Query: 491 VAMQDGDPTEYYSTAIVTVEERL-ATVKSGMSDVHAATGSPAELCVVLNDEKVEGV-WLK 548
+ + E T+ + E R A +K+ + + G L + N V W+
Sbjct: 26522 SIVHE----EITKTSQASEEVRTHAEIKAFSTQMSINEGQ--RLVLKANIAGATDVKWVL 26575
Query: 549 DGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTE---------------SE 593
+G E+T+ + G+ L EG T +K E S+
Sbjct: 26576 NGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSD 26635
Query: 594 ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEER 653
A FI+ P + + G G+P P++ W+K+ + ++
Sbjct: 26636 APAFISQP-------------RSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN 26682
Query: 654 VSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRV 708
VS+ R + L I N DSG +K KN G +AT L VL + P V
Sbjct: 26683 VSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREV 26737
Score = 83.6 bits (205), Expect = 1e-15
Identities = 80/296 (27%), Positives = 128/296 (43%), Gaps = 15/296 (5%)
Query: 417 IPIKFVSNLKNVRVKER----SRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKR 472
+P+KFV +K++ + E S A EC ++ W KDG + K+ +GK
Sbjct: 4616 VPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKD 4675
Query: 473 AELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAE 532
+L I D QLSD GEYT V ++ G+ + + +V E + VK+ +V G P
Sbjct: 4676 RKLHIIDVQLSDAGEYTCV-LRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 4734
Query: 533 LCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQ--GAVHKLIFPSMGPEHEGKYTFRAKGT 590
L LN E+ + VW KDGK + + PG +IV G + L G YT +
Sbjct: 4735 LSCELNKER-DVVWRKDGKIVVEKPG-RIVPGVIGLMRALTINDADDTDAGTYTVTVENA 4792
Query: 591 ES-EASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVT 649
+ E S + I +++ + VK TA K P + W+K E+
Sbjct: 4793 NNLECSSCVKVVEVIRDWLVKPIRDQ--HVKPKGTAIFACDI-AKDTPNIKWFKGYDEIP 4849
Query: 650 EE--ERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKP 703
E ++ + R + L I N + ED ++++ A TL ++ KP
Sbjct: 4850 AEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKP 4905
Score = 83.6 bits (205), Expect = 1e-15
Identities = 150/648 (23%), Positives = 250/648 (38%), Gaps = 101/648 (15%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
D+P P G +E L +S V ++W+ P+ +GG+ + + VE R G +W K + K
Sbjct: 23932 DKPSQP-GELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKD 23990
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETE-----EVFAGNPIEPPGFASQPQVTDV 813
F+ + E Y+FR+ A N G+S P T ++ +G E PG + ++ DV
Sbjct: 23991 KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSG---EAPGI--RKEMKDV 24045
Query: 814 TKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKC---------TVD 864
T T+ G A L + R W K+ IQ K T+
Sbjct: 24046 T-----------TKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094
Query: 865 GLLEDTEYE--FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLA 922
+ E+ E E + IA N+ G + S S ++ P PG + S++ L
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETS--SKLLLQATPQFHPGYPLKEKYYGAVGSTLRLH 24152
Query: 923 WREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGT---CYTVGGLIERQKYF--FRIRA 977
P + + E I I T + V ++R+ + ++++
Sbjct: 24153 VMYIGRPVPAMTWFHGQKLLQNSE-----NITIENTEHYTHLVMKNVQRKTHAGKYKVQL 24207
Query: 978 VNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV- 1036
N G + + LD ++ P + A LK+ V+ S PP D
Sbjct: 24208 SNVFGTVDAI-LDVEIQDKPDKPTGPIVIEALLKNSAVI------------SWKPPADDG 24254
Query: 1037 -IWQKDGVPTK-----GRETITKSKNHSQF---LINSTKRSDSGVY-RILLQNEFGEAR- 1085
W + V K G E S S ++N T+ ++G Y R+ QN FG +
Sbjct: 24255 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDP 24312
Query: 1086 ---YDIHVRVADFPRP--PTNLRLFEEVPNTVTLTWNHSPDVQEDGEA--HYIIMKRDAS 1138
+ + + F +P P + ++ + W P + G +Y + KR+
Sbjct: 24313 LEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWK--PPASDGGAKIRNYYLEKREKK 24370
Query: 1139 TATWYTAA-ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDL 1197
W + E + ++V L+ G +Y FRV N G+SE W ++
Sbjct: 24371 QNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESE-------W-------SEI 24416
Query: 1198 SAKLKPYEKKDWR-HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITAN 1256
S + P K D AP F L+ V + T+ C G+P+P V Y+ I A+
Sbjct: 24417 SEPITP--KSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIAD 24474
Query: 1257 SKFW--YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
+ G L+I + T D+ Y V N+ G + +L V
Sbjct: 24475 GLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24522
Score = 75.5 bits (184), Expect = 3e-13
Identities = 142/714 (19%), Positives = 258/714 (36%), Gaps = 116/714 (16%)
Query: 14 VSMEFSSSTTHVQTFSQTTKIVGEEVVR---RKSSSIVEFFSLVTRSSNIPAGDSV---P 67
+S E +S T++Q Q K + E+V + K S S VTR + A + + P
Sbjct: 26296 ISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKP 26355
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
V Q T A F + G +P W ++ G I + K
Sbjct: 26356 VIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKD-GKAITQGGKY------------- 26401
Query: 128 EPLTSDDSDNYKCIASNDHADA-IYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
L+ D + I D +D+ +YT ++ + G K +K + +KV+
Sbjct: 26402 -KLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA----IKDTEAQKVS 26456
Query: 187 NEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETK 246
+K ++ KK V E I K L +E
Sbjct: 26457 TQKTS-----------------------------EITPQKKAVVQEEIS-QKALRSEE-- 26484
Query: 247 VDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAG 306
+KM K E L ++ K + + K + ++ +
Sbjct: 26485 -----------------IKMSEAKSQEKLALKEEASKVLISEEVKKS----AATSLEKSI 26523
Query: 307 IYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKE 366
++ + S E+ E F +M + E Q V + ++ + W NG E
Sbjct: 26524 VHEEITKTSQASEEVRTHAEIKAFSTQMS---INEGQRLVLKANIAGAT-DVKWVLNGVE 26579
Query: 367 LKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTIDRI---PI 419
L ++Y VS G TL IK A D G + + G + + LT+ +
Sbjct: 26580 LTNSEEYRYGVS--GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAP 26637
Query: 420 KFVSNLKNVRVKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIE 478
F+S ++ + E CE++ + + W K+ + + S++ L I
Sbjct: 26638 AFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIR 26697
Query: 479 DAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLN 538
+A +SD G+YT+ A ++ +V L V+ +V T L +
Sbjct: 26698 NASVSDSGKYTIKAKNFRGQCSATASLMV-----LPLVEEPSREVVLRTSGDTSLQGSFS 26752
Query: 539 DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFI 598
+ V+ + K+ ++ ++ F SM + S + + I
Sbjct: 26753 SQSVQ---MSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26809
Query: 599 ADPPTIDPSVLEALAAHA-------------ITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
++ ++ S + L A I++ G + F G+P P+VTW G
Sbjct: 26810 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26869
Query: 646 MEVTEEE--RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
++ +E R +E +D L I + ++D GL L L N+ GS +AT+++ +
Sbjct: 26870 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 73.9 bits (180), Expect = 9e-13
Identities = 141/679 (20%), Positives = 253/679 (37%), Gaps = 92/679 (13%)
Query: 54 VTRSSNIPAGDSVP----EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIK 109
VT ++ +PA +P V + VT EG+ + G P ++W RE I+
Sbjct: 880 VTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYRED-YQIE 938
Query: 110 ESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKM 169
S + L + ++DS + C A N+ A + T L + E+ +
Sbjct: 939 SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNE-AGTVSTSCYLAVQVSEEFE---- 993
Query: 170 LKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKV 229
K+ EK E V +D V + T+ ++
Sbjct: 994 -----------KETTAVTEKFTTEEKRFVESRDV--VMTDTSLTE--------EQAGPGE 1032
Query: 230 EVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQM 289
I KP+ K + +VVF C + +P + W K PL Y KQ
Sbjct: 1033 PAAPYFITKPVVQKLVE-GGSVVFGCQVG-GNPKPHVYWKKSGVPLTTGYRYKVSYNKQT 1090
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKR--MSAELTVLDEP---LKFLGEMKPVKVTERQT 344
G + LVIS +DAG Y++ V +K SA ++L+E L + + + T+
Sbjct: 1091 G-ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTA 1149
Query: 345 AVFEIRLSKKEPNFVWKFNGKELKR---------------------DDKYEITVSEDGLT 383
V E ++ + P FV+ KE ++ D ++ I+ E+ L
Sbjct: 1150 FVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLI 1209
Query: 384 HTLKIKDARLSDSGEFSAEAGNLVQKAQLT-IDRIPIKFVSNLKNVRVKERSRACLECEL 442
++ + + + E E G ++ + + F S +KN R+ E C++
Sbjct: 1210 KEIEYRIIKTTLE-ELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKM 1268
Query: 443 TSKDVT-LRWKKDGQLLMHGTKYSMNH-EGKRAELIIEDAQLSDGGEYTVVAMQDGDPTE 500
+ + + W KDG+ + HG +Y M+ + RA L I D G YT A +
Sbjct: 1269 SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA------SN 1322
Query: 501 YYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQ 560
AI + + + + + T P L+ V I P
Sbjct: 1323 IKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSV------SRSPIRMSPARM 1376
Query: 561 IVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVK 620
+ + ++ M P + T ++ VF+ P + LE
Sbjct: 1377 SPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKP--VSFKCLE---------- 1424
Query: 621 VGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVREDSGLI 678
G TA + G+P+P+ W+ DG ++ + +V ++ Q+L+ + DSG
Sbjct: 1425 -GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVP-ATPSDSGEW 1482
Query: 679 LLKLKNDHGSATATLHLSV 697
+ +N G ++ ++ L+V
Sbjct: 1483 TVVAQNRAGRSSISVILTV 1501
Score = 73.6 bits (179), Expect = 1e-12
Identities = 142/671 (21%), Positives = 249/671 (37%), Gaps = 105/671 (15%)
Query: 76 VTAPEGDKAVFRARVQGNAKPHISWK-RESGIPIKESAKIFYDSINKEHVLKLEPLTSDD 134
+ A E D F V IS+K ++G+ IK + K + H L + + D
Sbjct: 2932 INAEEKDTITFEVTVNYEG---ISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGD 2988
Query: 135 SDNYKCIASNDHADAIYTVSLLVTEGQEKM-DFKKMLKKRA--------PPAPKKKQK-- 183
+ +Y +A + A V E ++ + D K + KKRA P + K
Sbjct: 2989 AADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDD 3048
Query: 184 ---------KVANEKEMLEILSKVPK-KDFEKVCMEYG--------FTDFRGLLRKLKEM 225
K+ EK + +L + D K + G F + R + +++ +
Sbjct: 3049 QELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDV--RIRSI 3106
Query: 226 KKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYS-LGKY 284
KK+V+V +E + V+ E+ + +V W K + Q KY
Sbjct: 3107 KKEVQV--------IEKQRAVVE--------FEVNEDDVDAHWYKDGIEINFQVQERHKY 3150
Query: 285 DVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTV-LDEPLKFLGEMKPVKVTERQ 343
V++ + + IS +DAG Y+ G R S L V EP + L E++PV V +
Sbjct: 3151 VVERR--IHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGK 3208
Query: 344 TAVFEIRLS-KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAE 402
A F +S + +P W + L K + DG +TL + +A D+ ++ E
Sbjct: 3209 PARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL--HDGQEYTLLLIEAFPEDAAVYTCE 3266
Query: 403 AGN----LVQKAQLTIDR------------IPIKFVSNLKNVRVKERSRACLECELTSKD 446
A N A L+++ P ++ L++ E A +C ++ D
Sbjct: 3267 AKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTD 3326
Query: 447 VTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAI 506
+ + W + + + M +L I +A D G YT VA S A+
Sbjct: 3327 LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA----------SNAV 3376
Query: 507 VTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGA 566
V +T + + E + + ++ +L +E +Q+ K
Sbjct: 3377 GQVS---STANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINE 3433
Query: 567 VHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAH 626
+L+ S P + K+ +GT +FI + D + +G A
Sbjct: 3434 TLELL--SESPVYPTKFDSEKEGT---GPIFIKEVSNAD-------------ISMGDVAT 3475
Query: 627 IKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDH 686
+ V G P PK+ W+ +G+ +T D L I ED G ND+
Sbjct: 3476 LSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDY 3535
Query: 687 GSATATLHLSV 697
G + +L +
Sbjct: 3536 GKTICSAYLKI 3546
Score = 68.6 bits (166), Expect = 4e-11
Identities = 108/486 (22%), Positives = 190/486 (39%), Gaps = 88/486 (18%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYS--------LSVG 313
P K+ W K + L + K G +Y L++ DA +Y+ ++
Sbjct: 3220 PQPKISWYKEEQLLSTGF---KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATT 3276
Query: 314 DKRMSAELTVLDEPLKFLGEMKPVKVT--------ERQTAVFEIRLSKKEPNFVWKFNGK 365
+S E+ + P + + P +T E Q A F+ R+S + W K
Sbjct: 3277 SASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDK 3336
Query: 366 ELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNL 425
++K + +T ED T+ L+I +A D G ++ A N V + T + + ++ ++
Sbjct: 3337 KIKPSRFFRMTQFED--TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN-LSLEAPESI 3393
Query: 426 KNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDG 485
+ R+++ E E+ K+ + + + +H + ++ + EL LS+
Sbjct: 3394 LHERIEQ------EIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLEL------LSES 3441
Query: 486 GEYTVVAMQDGDPTEYYS----TAIVTVEERLATVKSGMSDVHAATGSPAELCV-VLNDE 540
Y PT++ S T + ++E +S+ + G A L V V+
Sbjct: 3442 PVY---------PTKFDSEKEGTGPIFIKE--------VSNADISMGDVATLSVTVIGIP 3484
Query: 541 KVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA------------- 587
K + W +G +T + V G H LI E EG+YT A
Sbjct: 3485 KPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYL 3544
Query: 588 ---------KGTESEASVF-----IADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRG 633
K TE+E++V + P P L+ L I G A + G
Sbjct: 3545 KINSKGEGHKDTETESAVAKSLEKLGGP--CPPHFLKELKP--IRCAQGLPAIFEYTVVG 3600
Query: 634 KPLPKVTWYKDGMEV-TEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
+P P VTW+K+ ++ T + +++ REDSGL + K +N G +T
Sbjct: 3601 EPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCA 3660
Query: 693 LHLSVL 698
L VL
Sbjct: 3661 AELLVL 3666
Score = 68.2 bits (165), Expect = 5e-11
Identities = 46/164 (28%), Positives = 76/164 (46%), Gaps = 7/164 (4%)
Query: 546 WLKDGKEITD--LPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA---KGTESEASVFIAD 600
W +DG+ I+ LPG+QI KL P++ + G+Y+ +A G + + +
Sbjct: 39 WFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
T P+ ++ L ++TV+ G ++V G P P V +Y+DG E+ + +
Sbjct: 99 AETAPPNFVQRL--QSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEG 156
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
D L I+ EDSG + N G AT+T L V + P
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Score = 67.4 bits (163), Expect = 9e-11
Identities = 105/466 (22%), Positives = 185/466 (39%), Gaps = 44/466 (9%)
Query: 867 LEDTEYEFRVIAVN---KAGPGQPSVPSSSV-----------VAKDPVKPPGLVQDLHVS 912
+E+TE+ ++ N K G+ V S+V + P KP G + +
Sbjct: 24180 IENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV---IE 24236
Query: 913 DSSNSSISLAWREPAE--GDPPSGYILEM-RAEDTKEWSKCTKIPISGTCYTVGGLIERQ 969
+S ++W+ PA+ G + Y++E A++ EW + TC V L E
Sbjct: 24237 ALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENA 24295
Query: 970 KYFFRIRAVNEAGVGEPVELDKGVRAMPP---PAAP-KFDLSARLKSHMVVRAGTALCIH 1025
Y+FR+ A N G+ +P+E+ V P P AP K ++A K VV A
Sbjct: 24296 GYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVV----AWKPP 24351
Query: 1026 AAFSGSPPPDVIWQK-DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEA 1084
A+ G+ + +K + K T+ + F + + +R+ +N GE+
Sbjct: 24352 ASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGES 24411
Query: 1085 RYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
+ +++ P +++ + + P+ N + Q + + WY
Sbjct: 24412 EWS---EISEPITPKSDVPI--QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR 24466
Query: 1145 AAERVFSN--KYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLK 1202
+ + ++ KY + G Y+ ++A D+ R T N+ +A L+
Sbjct: 24467 QGKEIIADGLKYRIQEFKGG--YHQLIIASVTDDDATVYQVRAT---NQGGSVSGTASLE 24521
Query: 1203 PYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
E H P+ + + LRG+ ++ F G P P +T KG I N +
Sbjct: 24522 -VEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI 24580
Query: 1263 STSGVCTLVIPT-CTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
T +LV P KD+G Y V +N G D+ + L V D D
Sbjct: 24581 VTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPD 24626
Score = 63.9 bits (154), Expect = 1e-09
Identities = 106/485 (21%), Positives = 185/485 (38%), Gaps = 67/485 (13%)
Query: 52 SLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISW-KRESGIPIKE 110
S VT N P P+ +++ QPVT G A F A + G +P ISW K E +
Sbjct: 3181 SSVTLYVNAP---EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGF 3237
Query: 111 SAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKML 170
K +D +E+ L L +D+ Y C A ND+ A + SL V E E + + +
Sbjct: 3238 KCKFLHD--GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEM 3294
Query: 171 KKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVE 230
P Q V +E + +V D + + + D + + M + +
Sbjct: 3295 PVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLK---VSWYSKDKKIKPSRFFRMTQFED 3351
Query: 231 VEAIRILKPLEDKETKVDTTVVFDCIMELKD-PNVKMIWIKGTEPLRIQYSLGKYDVKQM 289
+ I + + E T V + + ++ N+ + + RI+ + + ++K+
Sbjct: 3352 TYQLEIAEAYPEDEGTY-TFVASNAVGQVSSTANLSLEAPESILHERIEQEI-EMEMKEF 3409
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDE----PLKFLGEMK---PVKVTER 342
+ ++ + + G++S + +++ L +L E P KF E + P+ + E
Sbjct: 3410 SSSFL------SAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEV 3463
Query: 343 QTAVFEIR---------LSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARL 393
A + + +P W FNG L Y+ DG H+L I +L
Sbjct: 3464 SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVF--DGDDHSLIILFTKL 3521
Query: 394 SDSGEFSAEA----GNLVQKAQLTIDR------------------------IPIKFVSNL 425
D GE++ A G + A L I+ P F+ L
Sbjct: 3522 EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKEL 3581
Query: 426 KNVRVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHE-GKRAELIIEDAQLS 483
K +R + A E + + T+ W K+ + L Y++ H I+ D Q
Sbjct: 3582 KPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQRE 3641
Query: 484 DGGEY 488
D G Y
Sbjct: 3642 DSGLY 3646
Score = 62.8 bits (151), Expect = 2e-09
Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 1/115 (0%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P V+ LK TV+ G+ T+ C G P PTVT Y+ D I ++ F SG+ L+I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD-KSVVASITESLQKKSKHLM 1326
+DSG ++ NE G +SC L V ++ + ++TE + K +
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFV 1011
Score = 62.8 bits (151), Expect = 2e-09
Identities = 127/605 (20%), Positives = 241/605 (39%), Gaps = 84/605 (13%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P ++ + VT G+ A ++ G P I W R G + +S K S + H L
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR-FGKELIQSRKYKMSSDGRTHTLT 24094
Query: 127 LEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
+ +D Y CIA+N+ + + T S L+ + + LK++ A +
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGE-VETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLR--- 24150
Query: 187 NEKEMLEILSKVPK----------KDFEKVCME----YGFTDFRGLLRKLKEMKKKVE-- 230
++ I VP ++ E + +E Y + + RK K KV+
Sbjct: 24151 --LHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLS 24208
Query: 231 -----VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTE---PLRIQYSLG 282
V+AI ++ ++DK K +V + +++ + + W + Y +
Sbjct: 24209 NVFGTVDAILDVE-IQDKPDKPTGPIVIEALLK---NSAVISWKPPADDGGSWITNYVVE 24264
Query: 283 KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDK---RMSAELTV-LDEPLKFLGEMKPVK 338
K + K+ G ++ LV S +++ I +L+ R+SA+ T + +PL+ +
Sbjct: 24265 KCEAKE-GAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKS 24323
Query: 339 VTERQTAVFE---IRLSKKEPNFVWK--------------FNGKELKRDDKYEITVSE-- 379
E+ A + ++K WK +E K++ +T E
Sbjct: 24324 PFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIR 24383
Query: 380 ----------DGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVR 429
+GL + ++K L E+S + + K+ + I F L+N+
Sbjct: 24384 ETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQ--APHFKEELRNLN 24441
Query: 430 VKERSRACLECELTSKDVTL-RWKKDG-QLLMHGTKYSMNH-EGKRAELIIEDAQLSDGG 486
V+ +S A L C++T + +W + G +++ G KY + +G +LII D
Sbjct: 24442 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDAT 24501
Query: 487 EYTVVAMQDGDPTEYYSTAIVTVEERLATVKS--GMSDVHAATGSPAELCVVLNDEKVEG 544
Y V A G ++ V V ++ K+ GM VHA G + + + +
Sbjct: 24502 VYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPV 24561
Query: 545 VWLKDGKEITDLPG-MQIVKQGAVHKLIFPSMGPEHE--GKYTFRAKG----TESEASVF 597
+ + G+++ D G Q++ + L+FP+ G E + G Y AK + +
Sbjct: 24562 ITWQKGQDLIDNNGHYQVIVTRSFTSLVFPN-GVERKDAGFYVVCAKNRFGIDQKTVELD 24620
Query: 598 IADPP 602
+AD P
Sbjct: 24621 VADVP 24625
Score = 59.7 bits (143), Expect = 2e-08
Identities = 70/309 (22%), Positives = 126/309 (40%), Gaps = 28/309 (9%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTK--GRETITKSKNHS 1058
AP F R ++ + G + SG P P++ W K+ +P +I++S+N
Sbjct: 26636 APAFISQPRSQN---INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVY 26692
Query: 1059 QFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNH 1118
I + SDSG Y I +N G+ + V L L EE V L +
Sbjct: 26693 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV---------LPLVEEPSREVVLRTSG 26743
Query: 1119 SPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDS 1178
+Q + + M A++ + FS+ + + + + + + + +S
Sbjct: 26744 DTSLQGSFSSQSVQMSASKQEASFSS-----FSSS-SASSMTEMKFASMSAQSMSSMQES 26797
Query: 1179 --EPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPH-TVLRGQDCTMTCA 1235
E S + N Q++ ++K+ K R P + L ++ G+ T+ CA
Sbjct: 26798 FVEMSSSSFMGISNMTQLESSTSKML---KAGIRGIPPKIEALPSDISIDEGKVLTVACA 26854
Query: 1236 FLGNPRPTVTLYKGDVNITANS--KFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGK 1293
F G P P VT G I + +F +T + TL+I +D G Y++ + NE G
Sbjct: 26855 FTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGS 26914
Query: 1294 DRSSCTLTV 1302
D ++ + +
Sbjct: 26915 DSATVNIHI 26923
Score = 57.4 bits (137), Expect = 9e-08
Identities = 77/307 (25%), Positives = 121/307 (39%), Gaps = 34/307 (11%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETI--TKSKNHS 1058
AP+ L R++SH V G P +V W +GV + I T +
Sbjct: 25876 APRITL--RMRSHRVP-CGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVL 25932
Query: 1059 QFLINSTKRSDSGVYRILLQNEFGEAR--YDIHVRVADFPRPPTNLRLFEEVPNTVTLTW 1116
I DSG YR + N GEA + V D+ + R EEVP +V
Sbjct: 25933 TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRR-DEEVPRSVF--- 25988
Query: 1117 NHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIG 1176
P++ EA+ + + S ++ V S L ++ ++
Sbjct: 25989 ---PELTRT-EAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 26044
Query: 1177 DSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAF 1236
+ + L+ + T + K+K A R +T + TV G+ +C
Sbjct: 26045 EEKSLEEKST-----------TRKIKT------TLAARILTKPRSMTVYEGESARFSCDT 26087
Query: 1237 LGNPRPTVT-LYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDR 1295
G P PTVT L KG V ++ +++ +T T I + D G+YSV+VEN GK
Sbjct: 26088 DGEPVPTVTWLRKGQV-LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQE 26146
Query: 1296 SSCTLTV 1302
+ TLT+
Sbjct: 26147 AEFTLTI 26153
Score = 55.8 bits (133), Expect = 3e-07
Identities = 99/494 (20%), Positives = 176/494 (35%), Gaps = 85/494 (17%)
Query: 316 RMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYE 374
R+ A + + P + +K V V E ++ E +S P W +++ ++
Sbjct: 885 RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQ 944
Query: 375 ITVSEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTID----------RIPIK 420
IT + G+ L I++A DSG F+ EAG + L + + K
Sbjct: 945 ITF-QSGIAR-LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1002
Query: 421 FVSNLKNVRVKERSRACLECELTSKDVT-------------------------------- 448
F + K V+ R + LT +
Sbjct: 1003 FTTEEKRF-VESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1061
Query: 449 -----LRWKKDGQLLMHGTKYSMNHEGKRAE--LIIEDAQLSDGGEYTVVAMQDGDPTEY 501
+ WKK G L G +Y +++ + E L+I D GEYT+V T
Sbjct: 1062 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS- 1120
Query: 502 YSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQI 561
++A + E + ++ T A + E G + ++ + I
Sbjct: 1121 -ASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALI 1179
Query: 562 VKQGAVHKLIFPSMGPEHE-----------GKYTFRAKGT----------ESEASVFIAD 600
K+ A ++ + + E + +R T E + +V I++
Sbjct: 1180 RKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISE 1239
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
++ + + I +G T H K+ G PLPK+ WYKDG + ER M+ +
Sbjct: 1240 SEAVESGFDSRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQ 1297
Query: 661 D-QALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
D +A L I + ED G+ N G+A + L V P P G ++
Sbjct: 1298 DGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV--EPAAPLGAPTYIPTLEPVSR 1355
Query: 720 MKWKAPKDNGGRPV 733
++ +P+ P+
Sbjct: 1356 IRSLSPRSVSRSPI 1369
Score = 54.3 bits (129), Expect = 8e-07
Identities = 33/96 (34%), Positives = 41/96 (42%)
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTL 1270
HAPR ++ H V GQ+ P V Y V + +SK Y +TSGV TL
Sbjct: 25875 HAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTL 25934
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKD 1306
I C DSG Y + N G+ TL V D
Sbjct: 25935 EILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGD 25970
Score = 52.8 bits (125), Expect = 2e-06
Identities = 66/296 (22%), Positives = 108/296 (36%), Gaps = 50/296 (16%)
Query: 251 VVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL 310
V + C +E D + ++ W G L + KY++ +L + ++ D G Y
Sbjct: 25088 VKYVCKIENYDQSTQVTWYFGVRQLE---NSEKYEITYEDGVAILYVKDITKLDDGTYRC 25144
Query: 311 SVGD-------------------------------KRMSAELTVLDEPLKFLGEMKPVKV 339
V + KR + + +L+ P +F +
Sbjct: 25145 KVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTA 25204
Query: 340 TERQTAVFEIRLS-KKEPNFVWKFNGKELKR-DDKYEITVSEDGLTHTLKIKDARLSDSG 397
+ F + ++ EP+ W +G+++K D+ + T D + L I D
Sbjct: 25205 YVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDA 25264
Query: 398 EFSAEAGNLVQ----KAQLTIDRIPIKFVSNLK--------NVRVKERSRACLECELTS- 444
E++ A N KA+LT+ P S L+ N +E C E ++
Sbjct: 25265 EYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGI 25324
Query: 445 KDVTLRWKKDGQLLMHGTKYSMNHEG-KRAELIIEDAQLSDGGEYTVVAMQDGDPT 499
TL+W+KDGQ L G + HEG L I D D G Y V A T
Sbjct: 25325 PPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGST 25380
Score = 52.4 bits (124), Expect = 3e-06
Identities = 70/313 (22%), Positives = 120/313 (38%), Gaps = 39/313 (12%)
Query: 999 PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-TKG---RETITKS 1054
PAAP F ++ + +V G ++ G+P P V W+K GVP T G + + K
Sbjct: 1033 PAAPYF-ITKPVVQKLV--EGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQ 1089
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+ +I+ T D+G Y I+++N+ GE + L EE + +
Sbjct: 1090 TGECKLVISMTFADDAGEYTIVVRNKHGET--------------SASASLLEEADYELLM 1135
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKY-YFRVVARN 1173
Q A ++ + TA + +E + +Y L +K VV R
Sbjct: 1136 KSQQEMLYQTQVTA-FVQEPKVGETAPGFVYSE--YEKEYEKEQALIRKKMAKDTVVVRT 1192
Query: 1174 EIGDSE-PLDSRDTWLINKDQIQDLSAKLKPYEKKDWRH------------APRFVTPLK 1220
+ D E + S + LI + + + + L+ ++D F + +K
Sbjct: 1193 YVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIK 1252
Query: 1221 PHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN-STSGVCTLVIPTCTLKD 1279
+ +L G T C G P P + YK I ++ + G +L IP +D
Sbjct: 1253 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312
Query: 1280 SGDYSVLVENELG 1292
G Y+ N G
Sbjct: 1313 EGIYTAFASNIKG 1325
Score = 52.4 bits (124), Expect = 3e-06
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFW--YNSTSGVCT 1269
AP F+T ++ G C GNP+P V K V +T ++ YN +G C
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
LVI D+G+Y+++V N+ G+ +S +L
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 51.2 bits (121), Expect = 6e-06
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 13/109 (11%)
Query: 989 LDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDG----VP 1044
L G+R +PP L S + + G L + AF+G P P+V W G
Sbjct: 26823 LKAGIRGIPPKIEA-------LPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQ 26875
Query: 1045 TKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG--EARYDIHVR 1091
+GR I + + + +I ++ D G+Y + L NEFG A +IH+R
Sbjct: 26876 EQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 26924
Score = 50.8 bits (120), Expect = 8e-06
Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 8/197 (4%)
Query: 330 FLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKI 388
F ++ V V E TA FE +S P W +G+ + + +S L I
Sbjct: 8 FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTI 67
Query: 389 KDARLSDSGEFSAEA----GNLVQKAQLTI--DRIPIKFVSNLKNVRVKERSRACLECEL 442
++SG +S +A G A+L + + P FV L+++ V++ S+ L+ +
Sbjct: 68 PAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRV 127
Query: 443 TSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEY 501
T +++ +DG + + ++ EG L+I +A D G Y+V A
Sbjct: 128 TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATS 187
Query: 502 YSTAIVTVEERLATVKS 518
+ +V EE + K+
Sbjct: 188 TAELLVQGEEEVPAKKT 204
Score = 50.4 bits (119), Expect = 1e-05
Identities = 25/96 (26%), Positives = 49/96 (51%)
Query: 1207 KDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG 1266
K+ AP F++ + + GQ+ TC G P P + +K ++ I+ +S + +
Sbjct: 26631 KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN 26690
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
V +L I ++ DSG Y++ +N G+ ++ +L V
Sbjct: 26691 VYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726
Score = 50.1 bits (118), Expect = 1e-05
Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVRE 673
++ V G TA + G P+P+V+W++DG ++ V + + +A LTI +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 674 DSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
+SG LK N G AT+T L V PP
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 50.1 bits (118), Expect = 1e-05
Identities = 84/364 (23%), Positives = 140/364 (38%), Gaps = 55/364 (15%)
Query: 384 HTLKIKD-------ARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSN-LKNVRVKERSR 435
HTL KD AR+S G ++ G V A++ + I I VS + + +E
Sbjct: 25030 HTLIKKDLNMVVSAARISCGGAIRSQKG--VSVAKVKVASIEIGPVSGQIMHAVGEEGGH 25087
Query: 436 ACLECELTSKDVTLR--WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAM 493
C++ + D + + W + L + KY + +E A L ++D D G Y +
Sbjct: 25088 VKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVV 25147
Query: 494 QD-GDPTEYYSTAIVTVEE-------RLATVKSGMSDVHAATGSPAELCVVLNDEKV--- 542
D G+ + Y + V E R +D P E + L ++
Sbjct: 25148 NDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVG 25207
Query: 543 EGV---------------WLKDGKEITDLPGMQIVK-----QGAVHKLIFPSMGPEHEGK 582
E V W K G++I PG K +++L S+ + + +
Sbjct: 25208 ENVRFGVTITVHPEPHVTWYKSGQKIK--PGDNDKKYTFESDKGLYQLTINSVTTDDDAE 25265
Query: 583 YTFRAKGTESEAS------VFIADPPTIDP--SVLEALAAHAITVKVGHTAHIKVPFRGK 634
YT A+ E S V + PPT + + L A+A + G + ++ G
Sbjct: 25266 YTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANA-ECQEGQSVCFEIRVSGI 25324
Query: 635 PLPKVTWYKDGMEVTEEERVSM-ERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
P P + W KDG ++ + + G D L I + + ED+G + N GS +
Sbjct: 25325 PPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQA 25384
Query: 694 HLSV 697
HL V
Sbjct: 25385 HLQV 25388
Score = 48.9 bits (115), Expect = 3e-05
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P FV L+ TV +G + G P P V Y+ I ++ F + + +L+I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD------KSVV--ASITESLQKK 1321
+DSG YSV N +G+ S+ L V +++ K++V A I+ES Q +
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 48.9 bits (115), Expect = 3e-05
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 3/99 (3%)
Query: 997 PPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTK---GRETITK 1053
PP + + RL ++ + G ++C SG PPP + W+KDG P E I +
Sbjct: 25290 PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHE 25349
Query: 1054 SKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRV 1092
++ I T D+G YR+ N G H++V
Sbjct: 25350 GLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 47.8 bits (112), Expect = 7e-05
Identities = 78/309 (25%), Positives = 120/309 (38%), Gaps = 29/309 (9%)
Query: 354 KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSD-SGEFSAEA----GNLVQ 408
KE N W F K + D+K++ +D T+TL I D GE+ EA G
Sbjct: 4270 KEVN--WYFENKLVPSDEKFKCL--QDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTAT 4325
Query: 409 KAQLTIDRIPIKFVSN-LKNVRVKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSM 466
A+LT+ + + ++ + V A CE+ S +V +W K G+ + K S+
Sbjct: 4326 SAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSI 4385
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
+ L I Q+ D GEYT A + +T VTV V+ + +
Sbjct: 4386 RSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKPE 4445
Query: 527 TGSPAELCVVL------NDEKVEGVWLKDGKE--ITDLPGMQIVKQGAV-------HKLI 571
L VL + KVE L+ K+ + + P + V++ V K+
Sbjct: 4446 PKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIP 4505
Query: 572 FPSMGPEHEGKYTFRA--KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKV 629
P+ PE + A + EA V PP ++P A + V VG A K
Sbjct: 4506 EPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPV-VGKKAEAKA 4564
Query: 630 PFRGKPLPK 638
P PK
Sbjct: 4565 PKEEAAKPK 4573
Score = 47.8 bits (112), Expect = 7e-05
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA---NSKFWYNSTSGVCT 1269
P F PL T G++ +P P VT YK I + K+ + S G+
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25252
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L I + T D +Y+V+ N+ G+D LTV
Sbjct: 25253 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 47.4 bits (111), Expect = 9e-05
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSK-FWYNSTSGVCTL 1270
AP+ ++ TV +G D +G P P YK V I + + +WY VC L
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCEL 2090
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQ 1319
VI T +DS V N G+ S L V K + + T+ LQ
Sbjct: 2091 VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ----LITFTQELQ 2135
Score = 47.4 bits (111), Expect = 9e-05
Identities = 55/226 (24%), Positives = 100/226 (44%), Gaps = 30/226 (13%)
Query: 220 RKLKEMKKKVEVEAIRILK-------PLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGT 272
R +K++K++ + +R+L+ PL +K V V F + + P + W K
Sbjct: 25174 RTMKKIKRRTDT--MRLLERPPEFTLPLYNKTAYVGENVRFGVTITVH-PEPHVTWYKSG 25230
Query: 273 EPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPL 328
+ ++ + KY + Y L I++V +D Y++ G+ A+LTV P
Sbjct: 25231 QKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPP 25290
Query: 329 KFLGEMKPV--------KVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSE 379
++P+ + E Q+ FEIR+S P W+ +G+ L EI
Sbjct: 25291 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII--H 25348
Query: 380 DGLT-HTLKIKDARLSDSGEF----SAEAGNLVQKAQLTIDRIPIK 420
+GL + L I+D D+G + + AG+ +A L ++R+ K
Sbjct: 25349 EGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYK 25394
Score = 45.4 bits (106), Expect = 4e-04
Identities = 69/296 (23%), Positives = 111/296 (37%), Gaps = 39/296 (13%)
Query: 1032 PPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P +VIW K + + GR I +I + D+G Y L + + + +H
Sbjct: 5992 PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVH 6051
Query: 1090 VRVADFPRPPTNLRLFE-EVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAER 1148
A+F P NL + E E V S VQ KRD T
Sbjct: 6052 ELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQ---------WKRDDKTLE------- 6095
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKD 1208
+KY V + G+K R + L T+++ + +A L EK
Sbjct: 6096 -SGDKYDV--IADGKK-------RVLVVKDATLQDMGTYVVMVGAAR-AAAHLTVIEKL- 6143
Query: 1209 WRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVC 1268
R V PLK V Q+ C + ++ + I +SK+ V
Sbjct: 6144 -----RIVVPLKDTRVKEQQEVVFNCE-VNTEGAKAKWFRNEEAIFDSSKYIILQKDLVY 6197
Query: 1269 TLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASI--TESLQKKS 1322
TL I L D +Y+V + N G++ S + +++D +V + E+++KKS
Sbjct: 6198 TLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKS 6253
Score = 45.4 bits (106), Expect = 4e-04
Identities = 74/329 (22%), Positives = 131/329 (39%), Gaps = 40/329 (12%)
Query: 369 RDDKYEITVSEDGLTHTLKIKDARLSDSG--EFSAEAGNLVQKAQLTIDRIPIKFVSNLK 426
R+ K ++T + + L+ A + + E S E + +K + T+ + ++ +
Sbjct: 26015 REVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTL---AARILTKPR 26071
Query: 427 NVRVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDG 485
++ V E A C+ + V T+ W + GQ+L ++ + ++ I Q SD
Sbjct: 26072 SMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDE 26131
Query: 486 GEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGV 545
G Y+VV E T +T+++ T K+ S + P V + E V
Sbjct: 26132 GNYSVVVENSEGKQEAEFT--LTIQKARVTEKAVTSPPRVKSPEPR----VKSPEAV--- 26182
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
K K + + + K + P+ E K T TE + ++ PP I
Sbjct: 26183 --KSPKRVKS-------PEPSHPKAVSPT-----ETKPT----PTEKVQHLPVSAPPKI- 26223
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL- 664
L+A A+ I K+ V R K +VTWYKDG ++ E D
Sbjct: 26224 TQFLKAEASKEI-AKLTCVVESSV-LRAK---EVTWYKDGKKLKENGHFQFHYSADGTYE 26278
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATL 693
L I+N D G + ++ + G++ L
Sbjct: 26279 LKINNLTESDQGEYVCEISGEGGTSKTNL 26307
Score = 45.1 bits (105), Expect = 5e-04
Identities = 32/106 (30%), Positives = 42/106 (39%)
Query: 1197 LSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITAN 1256
++ K +P + P VT L+ TV G PRPT K IT
Sbjct: 26339 VTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG 26398
Query: 1257 SKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
K+ + G L I DSG Y+ V+N G SSC LT+
Sbjct: 26399 GKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26444
Score = 43.9 bits (102), Expect = 0.001
Identities = 40/196 (20%), Positives = 77/196 (39%), Gaps = 14/196 (7%)
Query: 509 VEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVH 568
++E + + + D + G L + + K E W + K + + ++ +
Sbjct: 4238 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAK-EVNWYFENKLVPSDEKFKCLQDQNTY 4296
Query: 569 KLIFPSMGPE-HEGKYTFRA------KGTESEASVFIADPPTIDPSVLEALAAHAITVKV 621
L+ + E H+G+Y A T ++ +V P I + + V +
Sbjct: 4297 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKI------EPLEVAL 4350
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
GH A + P + W+K G E+ E ++ S+ + + L I D G K
Sbjct: 4351 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCK 4410
Query: 682 LKNDHGSATATLHLSV 697
N++GS + T L+V
Sbjct: 4411 ASNEYGSVSCTATLTV 4426
Score = 43.1 bits (100), Expect = 0.002
Identities = 46/213 (21%), Positives = 81/213 (38%), Gaps = 6/213 (2%)
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMS---DVHAATGSPAELCVVLNDEKVEGV 545
+V + G +AI T+++ L+ S V A T P+E V +
Sbjct: 776 SVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQF 835
Query: 546 WLKDGKEI-TDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
D + G+++ K+ V E + AK TE+ + P
Sbjct: 836 PFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVT 895
Query: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL 664
P+++ L +TV G + ++ G P P VTWY++ ++ + A
Sbjct: 896 PPTLVSGLKN--VTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIAR 953
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
L I EDSG N+ G+ + + +L+V
Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 43.1 bits (100), Expect = 0.002
Identities = 73/336 (21%), Positives = 119/336 (35%), Gaps = 70/336 (20%)
Query: 1030 GSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
G P P+ W DG V + + K +I SDSG + ++ QN G +
Sbjct: 1436 GRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSI 1495
Query: 1087 DI--HVRVADFPRPP--------TNLRLFEEVPNTVTLTWNHSPDVQ------------- 1123
+ V + P N++ + V T N +PD+
Sbjct: 1496 SVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKY 1555
Query: 1124 -------EDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTG-----------------L 1159
GEA I + + WYTA + + T +
Sbjct: 1556 PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLI 1615
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSR---DTWLINKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
+P Y + +A E+ EPL R + W + + D + KP+ KK +
Sbjct: 1616 IPRGTYRAKEIAAPEL---EPLHLRYGQEQW--EEGDLYDKEKQQKPFFKKK-------L 1663
Query: 1217 TPLKPHTVLRGQ-DCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
T L+ +C +T +G+P V + A ++ + G C+L
Sbjct: 1664 TSLRLKRFGPAHFECRLTP--IGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVA 1721
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVV 1311
+DSG + N+ G D +S TL V KD+KS+V
Sbjct: 1722 YSRDSGIITCRATNKYGTDHTSATLIV--KDEKSLV 1755
Score = 42.7 bits (99), Expect = 0.002
Identities = 57/273 (20%), Positives = 106/273 (38%), Gaps = 30/273 (10%)
Query: 1032 PPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P V W KD + R I K K + LI ST+ SD+G Y ++ A+ +
Sbjct: 3038 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3097
Query: 1090 VRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERV 1149
R +++ E+ V N ++D +AH+ +D + ER
Sbjct: 3098 GRDVRIRSIKKEVQVIEKQRAVVEFEVN-----EDDVDAHWY---KDGIEIN-FQVQER- 3147
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
+KY V R + R I ++ D+ + + ++ + E
Sbjct: 3148 --HKYVVE----------RRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPE---- 3191
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
P+ + L+P TV G+ G P+P ++ YK + ++ K + T
Sbjct: 3192 --PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3249
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L++ +D+ Y+ +N+ G +S +L+V
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 42.4 bits (98), Expect = 0.003
Identities = 25/112 (22%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P F+ + + G T++ +G P+P + + V +T ++ + + +L+I
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK----DDKSVVASITESLQK 1320
L+D G+Y+ + N+ GK S L + K D +++ +SL+K
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEK 3568
Score = 42.4 bits (98), Expect = 0.003
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
Query: 1198 SAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS 1257
SA K EK P F+ LKP +G +G P PTVT +K + + +
Sbjct: 3560 SAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSV 3619
Query: 1258 KFW-YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKD 1306
+ ++ +G T ++ +DSG Y EN LG+ + L V +D
Sbjct: 3620 YYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLED 3669
Score = 42.0 bits (97), Expect = 0.004
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 588 KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGME 647
K +E + V P T+D + L + V G + + KP +V WY +G+E
Sbjct: 25857 KTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVE 25916
Query: 648 VTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSAT--ATLHLS 696
+ E ++ L I +C +DSG N G A+ ATL ++
Sbjct: 25917 LQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVT 25967
Score = 40.0 bits (92), Expect = 0.015
Identities = 33/111 (29%), Positives = 45/111 (40%), Gaps = 15/111 (13%)
Query: 1002 PKFDLSARLKSHMV---VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE-----TITK 1053
P+F L K+ V VR G + +H P P V W K G K + T
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVH------PEPHVTWYKSGQKIKPGDNDKKYTFES 25246
Query: 1054 SKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRL 1104
K Q INS D Y ++ +N++GE + V P PPT+ L
Sbjct: 25247 DKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHP-PPTDSTL 25296
Score = 39.7 bits (91), Expect = 0.019
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS--KFWYNSTSGVCT 1269
AP F PL+ VL G T G P P V+ ++ I+ ++ + + G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L IP T +SG YS+ N G+ S+ L V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 39.7 bits (91), Expect = 0.019
Identities = 62/301 (20%), Positives = 101/301 (33%), Gaps = 54/301 (17%)
Query: 1008 ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKS---KNHSQFLINS 1064
+R+K++ ++ G + H SG P P + W KDG K E + I
Sbjct: 1249 SRIKNYRILE-GMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPV 1307
Query: 1065 TKRSDSGVYRILLQNEFGEARYD--IHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDV 1122
D G+Y N G A ++V A PT + E V +L+
Sbjct: 1308 VLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLS------- 1360
Query: 1123 QEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
R S + + R+ + + + P R + L+
Sbjct: 1361 -----------PRSVSRSPIRMSPARMSPARMSPARMSPAR-----------MSPGRRLE 1398
Query: 1183 SRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP 1242
D + Q++ L + P FV L GQ +G P P
Sbjct: 1399 ETD-----ESQLERL-------------YKPVFVLKPVSFKCLEGQTARFDLKVVGRPMP 1440
Query: 1243 -TVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLT 1301
T + G + + G +L+I T DSG+++V+ +N G+ S LT
Sbjct: 1441 ETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILT 1500
Query: 1302 V 1302
V
Sbjct: 1501 V 1501
Score = 39.7 bits (91), Expect = 0.019
Identities = 42/183 (22%), Positives = 70/183 (38%), Gaps = 14/183 (7%)
Query: 9 MLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAG----- 63
+L E + E + + + G + S I E L++ S P
Sbjct: 3393 ILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEK 3452
Query: 64 -DSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKE 122
+ P F+++ GD A V G KP I W +G+ + SA + +
Sbjct: 3453 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFF-NGVLLTPSADYKFVFDGDD 3511
Query: 123 HVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV-TEGQEKMDFK------KMLKKRAP 175
H L + +D Y C+ASND+ I + L + ++G+ D + K L+K
Sbjct: 3512 HSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGG 3571
Query: 176 PAP 178
P P
Sbjct: 3572 PCP 3574
Score = 39.7 bits (91), Expect = 0.019
Identities = 32/131 (24%), Positives = 52/131 (39%), Gaps = 6/131 (4%)
Query: 52 SLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKES 111
S V +S G P F+++ +P+ +G A+F V G P ++W +E+ +
Sbjct: 3560 SAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENK---QLC 3616
Query: 112 AKIFYDSI---NKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKK 168
++Y I N + +DS Y C A N ++ LLV M
Sbjct: 3617 TSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTP 3676
Query: 169 MLKKRAPPAPK 179
K P AP+
Sbjct: 3677 CKAKSTPEAPE 3687
Score = 39.7 bits (91), Expect = 0.019
Identities = 49/220 (22%), Positives = 90/220 (40%), Gaps = 24/220 (10%)
Query: 80 EGDKAVFRARVQGNAKPHISWKRE-SGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNY 138
EG F RV G P + W+++ + + + +I ++ ++ + L + +D+ Y
Sbjct: 25311 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD-YYALHIRDTLPEDTGYY 25369
Query: 139 KCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANEKEMLEILS-- 196
+ A+N L V E++ +KK K + QK++ M EILS
Sbjct: 25370 RVTATNTAGSTSCQAHLQV----ERLRYKKQEFKSKEEHERHVQKQIDKTLRMAEILSGT 25425
Query: 197 ------KVPKKDFEKVCMEY----GFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETK 246
+V K+ + + Y +G R E+++K E +R+ + +
Sbjct: 25426 ESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFR--LEIEEKKEERKLRMPYDVPEPRKY 25483
Query: 247 VDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSL-GKYD 285
TT+ D ++ P M W K +R QY + GK D
Sbjct: 25484 KQTTIEEDQRIKQFVPMSDMKWYK---KIRDQYEMPGKLD 25520
Score = 39.3 bits (90), Expect = 0.025
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 3/89 (3%)
Query: 618 TVKVGHTAHIKVPFRGKPLPKVTWYKDGMEV---TEEERVSMERGEDQALLTISNCVRED 674
T VG V P P VTWYK G ++ +++ + E + LTI++ +D
Sbjct: 25203 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25262
Query: 675 SGLILLKLKNDHGSATATLHLSVLDRPKP 703
+ +N +G + L+V P P
Sbjct: 25263 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 25291
Score = 38.5 bits (88), Expect = 0.043
Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 1/106 (0%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV-L 125
P F + Q V EG A F A + G P +SW R+ + + S + L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171
+ +T +S Y A+N A T LLV +F + L+
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ 111
Score = 38.5 bits (88), Expect = 0.043
Identities = 32/145 (22%), Positives = 60/145 (41%), Gaps = 10/145 (6%)
Query: 17 EFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGDSVPEFVEKPQPV 76
++ +++ + F + + V + RR I R+ + + PEF
Sbjct: 25149 DYGEDSSYAELFVKGVREVYDYYCRRTMKKIKR------RTDTMRLLERPPEFTLPLYNK 25202
Query: 77 TAPEGDKAVFRARVQGNAKPHISWKRESGIPIK---ESAKIFYDSINKEHVLKLEPLTSD 133
TA G+ F + + +PH++W + SG IK K ++S + L + +T+D
Sbjct: 25203 TAYVGENVRFGVTITVHPEPHVTWYK-SGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25261
Query: 134 DSDNYKCIASNDHADAIYTVSLLVT 158
D Y +A N + + L VT
Sbjct: 25262 DDAEYTVVARNKYGEDSCKAKLTVT 25286
Score = 37.7 bits (86), Expect = 0.074
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 81 GDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKC 140
G+ V G +P+ISW ++ G P+K++ ++ + VL ++ DD Y
Sbjct: 17829 GEDLKIEIPVIGRPRPNISWVKD-GEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 17887
Query: 141 IASNDHADAIYTVSLLVTE 159
A+N A +S++V E
Sbjct: 17888 TATNSAGTATENLSVIVLE 17906
Score = 37.4 bits (85), Expect = 0.096
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 1/98 (1%)
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
+ P V +P VL G+ C G P+P V Y I + +F G+
Sbjct: 1792 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHY 1850
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
L I C D+G+ V EN G L + ++D
Sbjct: 1851 LDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1888
Score = 37.0 bits (84), Expect = 0.13
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 1029 SGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG 1082
+G P P IW KDG + G+ +++ K I+ T SDSG+Y ++N G
Sbjct: 26379 TGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAG 26434
Score = 35.8 bits (81), Expect = 0.28
Identities = 25/93 (26%), Positives = 36/93 (38%)
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
R AP ++P V G TC P +K I + K S+ + +
Sbjct: 4334 RAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISS 4393
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L I + D G+Y+ NE G + TLTV
Sbjct: 4394 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426
Score = 35.4 bits (80), Expect = 0.37
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDG----VPTKGRETITKSKNHSQFLINSTKRSD 1069
+VV G+ A SG P P+V W +DG T I+ S ++ I + +++
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKAN 74
Query: 1070 SGVYRILLQNEFGEARYDIHVRVADFPRPP 1099
SG Y + N G+A + V PP
Sbjct: 75 SGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 35.4 bits (80), Expect = 0.37
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 4/119 (3%)
Query: 54 VTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAK 113
+T S++P P F E+ + + A +V G+ KP + W R+ I + K
Sbjct: 24420 ITPKSDVPI--QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 24477
Query: 114 I-FYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171
+ H L + +T DD+ Y+ A+N T SL V E K+ K L+
Sbjct: 24478 YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV-EVPAKIHLPKTLE 24535
Score = 35.0 bits (79), Expect = 0.48
Identities = 29/101 (28%), Positives = 41/101 (40%), Gaps = 7/101 (6%)
Query: 1030 GSPPPDVIWQKDG--VPTKGRETITKSKNHS-QFLINSTKRSDSGVYRILLQNEFGEARY 1086
G P P V W K+ + T TI + N S F++N +R DSG+Y +N GE+
Sbjct: 3600 GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTC 3659
Query: 1087 DIHVRV----ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQ 1123
+ V D P + E P T P V+
Sbjct: 3660 AAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVE 3700
Score = 34.3 bits (77), Expect = 0.82
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDG---VPTK-GRETITKSKNHSQFLINSTKRSDSG 1071
++ G+ L + +G+P PD++W K+ VP K + I +K + I+ST DS
Sbjct: 1521 IKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSA 1580
Query: 1072 VYRILLQNEFGE--ARYDIHVRVADFPRPPTNLRL 1104
Y N+ G R ++V V +F P +L
Sbjct: 1581 WYTATAINKAGRDTTRCKVNVEV-EFAEPEPERKL 1614
Score = 33.9 bits (76), Expect = 1.1
Identities = 30/134 (22%), Positives = 62/134 (46%), Gaps = 12/134 (8%)
Query: 296 VISNVNMNDAGIYSLSVGDKR-----MSAELTVLDEPLKFLGEMKPV----KVTERQTAV 346
VI+N+ + ++ + +++ S + ++ + L ++KP V Q
Sbjct: 16692 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 16751
Query: 347 FEIRLS-KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
E+ +S + +P W +G LK+ + +T S D LT TL IK+ D G++ N
Sbjct: 16752 IEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD-LT-TLSIKETHKDDGGQYGITVAN 16809
Query: 406 LVQKAQLTIDRIPI 419
+V + +I+ + +
Sbjct: 16810 VVGQKTASIEIVTL 16823
Score = 33.5 bits (75), Expect = 1.4
Identities = 36/161 (22%), Positives = 65/161 (40%), Gaps = 12/161 (7%)
Query: 973 FRIRAVNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGS 1031
+ ++A N +G EL PP + RL+S M VR G+ + + +G
Sbjct: 78 YSLKATNGSGQATSTAELLVKAETAPP------NFVQRLQS-MTVRQGSQVRLQVRVTGI 130
Query: 1032 PPPDVIWQKDGVPTKGR--ETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P P V + +DG + I++ + LI DSG Y + N G A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAE 190
Query: 1090 VRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHY 1130
+ V P + + + +T ++ + +++ EAH+
Sbjct: 191 LLVQGEEEVPA--KKTKTIVSTAQISESRQTRIEKKIEAHF 229
Score = 33.1 bits (74), Expect = 1.8
Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 76 VTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDS 135
V A GD V G KP ++WK+ I +K++ ++ +++ +L + DS
Sbjct: 14578 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQI-LKQTQRVNFETTATSTILNINECVRSDS 14636
Query: 136 DNYKCIASN 144
Y A N
Sbjct: 14637 GPYPLTARN 14645
Score = 33.1 bits (74), Expect = 1.8
Identities = 33/135 (24%), Positives = 53/135 (39%), Gaps = 17/135 (12%)
Query: 26 QTFSQT--TKIVGEEVVRRKSSSIVEFFSLVTR----SSNIPAGD-SVPEFVEKPQ---- 74
QT+S +K EV + K S++EF S + G +V E + P+
Sbjct: 21010 QTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLS 21069
Query: 75 -----PVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEP 129
VT G +G KP ISW ++ G+P+KES + + + L ++
Sbjct: 21070 DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKD-GLPLKESEFVRFSKTENKITLSIKN 21128
Query: 130 LTSDDSDNYKCIASN 144
+ Y I N
Sbjct: 21129 AKKEHGGKYTVILDN 21143
Score = 33.1 bits (74), Expect = 1.8
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEF 399
P WK LK D+ IT ++D TL +KD+ DSG +
Sbjct: 22180 PKVTWKLEEMRLKETDRVSITTTKD--RTTLTVKDSMRGDSGRY 22221
Score = 32.7 bits (73), Expect = 2.4
Identities = 64/277 (23%), Positives = 104/277 (37%), Gaps = 48/277 (17%)
Query: 1036 VIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEF---GEARYDIHVRV 1092
V W KDG K K K + G RIL+ N+ EA Y VR
Sbjct: 5907 VKWFKDGAEIK------KGKKYDII--------SKGAVRILVINKCLLDDEAEYSCEVRT 5952
Query: 1093 ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYII-MKRDASTATWYTAAERVF- 1150
A T L EE T L + +V E + + + + WY E +
Sbjct: 5953 ARTSGMLTVLE--EEAVFTKNLA---NIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIE 6007
Query: 1151 SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSR--DTWLINKDQIQDLSAKLKPYEKKD 1208
+ +Y + L GRK V+ + D+ + R + K ++ +L+A+
Sbjct: 6008 TGRYEI--LTEGRKRIL-VIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAE-------- 6056
Query: 1209 WRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVC 1268
F++ + +L G+ C+ P V + D + + K+ +
Sbjct: 6057 ------FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKKR 6109
Query: 1269 TLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
LV+ TL+D G Y V+V G R++ LTV +K
Sbjct: 6110 VLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6142
Score = 32.3 bits (72), Expect = 3.1
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query: 280 SLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMK 335
SL K ++ + +L++ NVN D+G Y L+V G K + VLD P G +
Sbjct: 15404 SLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTP----GPPQ 15459
Query: 336 PVKVTE 341
+KV E
Sbjct: 15460 DLKVKE 15465
Score = 32.0 bits (71), Expect = 4.0
Identities = 15/54 (27%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 1247 YKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
Y DV + +N K+ S G L + T +D G+YS +++ + +++C L
Sbjct: 2254 YHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK----KTTCKL 2303
Score = 32.0 bits (71), Expect = 4.0
Identities = 57/243 (23%), Positives = 90/243 (37%), Gaps = 27/243 (11%)
Query: 1067 RSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDG 1126
RS+ V+ + L++ E ++ + DF T+ LF + P V T E+G
Sbjct: 5747 RSEGKVHTLTLRDVKLEDAGEVQLTAKDFK---THANLFVKEP-PVEFTKPLEDQTVEEG 5802
Query: 1127 EAHYII--MKRDASTATWY-TAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDS 1183
+ + R+ + W+ E + S KY + GR V + I D P D
Sbjct: 5803 ATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVA--DGR------VRKLVIHDCTPEDI 5854
Query: 1184 RDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPT 1243
+ KD + + P + F+ PL V + C L
Sbjct: 5855 KTYTCDAKDFKTSCNLNVVPPHVE-------FLRPLTDLQVREKEMARFECE-LSRENAK 5906
Query: 1244 VTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVY 1303
V +K I K+ S V LVI C L D +YS E+ R+S LTV
Sbjct: 5907 VKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC----EVRTARTSGMLTVL 5962
Query: 1304 DKD 1306
+++
Sbjct: 5963 EEE 5965
Score = 32.0 bits (71), Expect = 4.0
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 11/70 (15%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAEL 321
PNV +W K LR + + D ++ L I N N ND+G Y+L++ + +A L
Sbjct: 19719 PNV--LWSKPDTDLRTRAYVDTTD-----SRTSLTIENANRNDSGKYTLTIQNVLSAASL 19771
Query: 322 T----VLDEP 327
T VLD P
Sbjct: 19772 TLVVKVLDTP 19781
Score = 32.0 bits (71), Expect = 4.0
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 9/70 (12%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRM 317
P +W K L + + D+ + L + N N NDAG Y+L+V G K +
Sbjct: 21888 PTPTAVWSKPDSNLSL-----RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSI 21942
Query: 318 SAELTVLDEP 327
+ + VLD P
Sbjct: 21943 TFTVKVLDTP 21952
Score = 31.6 bits (70), Expect = 5.3
Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 11/129 (8%)
Query: 224 EMKKKVEVEAIRI-LKPLEDKETKVDTTVVFDCIME-LKDPNVKMIWIKGTEPLRIQYSL 281
E ++K+ ++ + +K +E K TTV F I+ + P K W ++
Sbjct: 11003 ECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAK--WTTDGSEIKTDEH- 11059
Query: 282 GKYDVKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMKPV 337
Y V+ +L I N D G Y ++V G K ++ LTVLD P G + +
Sbjct: 11060 --YTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINIL 11117
Query: 338 KVTERQTAV 346
VT +
Sbjct: 11118 DVTPEHMTI 11126
Score = 30.8 bits (68), Expect = 9.0
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
Query: 277 IQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPLKFLG 332
IQ SL + + Q G Y L+I+ D+G YS+ SVG +AEL V E
Sbjct: 144 IQSSLD-FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Query: 333 EMKPVKVTERQTAVFEIRLSKK 354
+ K + T + + + R+ KK
Sbjct: 203 KTKTIVSTAQISESRQTRIEKK 224
>gi|133908641 myosin binding protein C, fast type [Homo sapiens]
Length = 1141
Score = 310 bits (793), Expect = 8e-84
Identities = 254/903 (28%), Positives = 390/903 (43%), Gaps = 61/903 (6%)
Query: 429 RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
+V ++ L E++ D+TL+W K+GQ + +KY + GK+ L I L+D Y
Sbjct: 267 QVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAY 326
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLK 548
V + TE + V+E + + + D G E+ V +++E + +W+K
Sbjct: 327 EVAVKDEKCFTELF------VKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMK 380
Query: 549 DGKEITDLPGMQ----IVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
DG E+T + K G H LIF + E G+Y G + EA + + +
Sbjct: 381 DGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQL- 439
Query: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVT--WYKDGMEVTEEERVSMERGEDQ 662
VL+ +A +TVK A K + KVT WYK+G+EV +R+++
Sbjct: 440 --EVLQDIAD--LTVKASEQAVFKCEVSDE---KVTGKWYKNGVEVRPSKRITISHVGRF 492
Query: 663 ALLTISNCVREDSGLILLKLKNDHGSATATLH-----LSVLDRPKPPQGRVEFLELSGSC 717
L I + ED G S +A L+ + + + +PP+ L+ SG
Sbjct: 493 HKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIH---LDCSGKT 549
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEV----DGKV--------TNFSTNK 765
N R E V +W+K EV +G+ ++F
Sbjct: 550 SENAIVVVAGNKLRLDVSITGEPPPVA--TWLKGDEVFTTTEGRTRIEKRVDCSSFVIES 607
Query: 766 VEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAP 825
+ ++ I N G + +F ++ P ++T V ++ + W P
Sbjct: 608 AQREDEGRYTIKVTNPVGE----DVASIFL-QVVDVPDPPEAVRITSVGEDWAILVWEPP 662
Query: 826 TQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPG 885
DGG PV GY+VER+KKGS W+ +N + T ++E YE RV AVN G
Sbjct: 663 MYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVS 722
Query: 886 QPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAED 943
QPS+ + + P+ P L V D ++++ +L WR P GY++E E
Sbjct: 723 QPSMNTKPFM---PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEG 779
Query: 944 TKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPK 1003
++EW P+ +TV L + FR+ VN AG EP L + V PK
Sbjct: 780 SEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPK 839
Query: 1004 FDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-TKGRETITKSKNHSQFLI 1062
L L+ + + G L + F G P P V+W K G P R + S + F +
Sbjct: 840 IRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFV 899
Query: 1063 NSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDV 1122
RSDSG Y + +Q E + I +RV + PP N+ + E + W D
Sbjct: 900 RQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDD 959
Query: 1123 QEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE-PL 1181
Y + K D T W+ ER TV+ L+ G +YYFRV N G S+ P
Sbjct: 960 GNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPG 1019
Query: 1182 DSRDTWLINKDQIQDLSAKLKPYEKK--DWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGN 1239
S++T I K I KP+E K D+R AP+F+TPL V+ G + CA G+
Sbjct: 1020 VSKNTARILKTGI-----TFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGH 1074
Query: 1240 PRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCT 1299
P+P V K + I + KF + GV TL I + D+G Y+ NELG+ + C
Sbjct: 1075 PKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECK 1134
Query: 1300 LTV 1302
L V
Sbjct: 1135 LEV 1137
Score = 244 bits (624), Expect = 3e-64
Identities = 254/1000 (25%), Positives = 398/1000 (39%), Gaps = 131/1000 (13%)
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGNA---KPHISWKRESGIPIKESAKIFYDSINKEHVL 125
F++KP V+ G AV A+V G KP I W + +
Sbjct: 54 FLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLE------------------ 95
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSL------LVTEGQEKMDFKKMLKKRAPPAPK 179
L S + S++ A +YTV L L G +++ K K
Sbjct: 96 ----LGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKA--KDTCDSCGF 149
Query: 180 KKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRK---LKEMKKKVEVEAIRI 236
+ + + L K+ EK G DF GLL+K ++E KKK
Sbjct: 150 NIDVEAPRQDASGQSLESF-KRTSEKKSDTAGELDFSGLLKKREVVEEEKKK-------- 200
Query: 237 LKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLV 296
K +D + + I EL +KG + K + +++ +Y
Sbjct: 201 -KKKDDDDLGIPPE-----IWEL---------LKGAK---------KSEYEKIAFQY--- 233
Query: 297 ISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAV-FEIRLSKKE 355
GI L KR+ + + F ++ P +R + + +S +
Sbjct: 234 ---------GITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPD 284
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTID 415
W NG+E+K KY G L I L+D + + +L +
Sbjct: 285 LTLKWFKNGQEIKPSSKY--VFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVK 342
Query: 416 RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHG----TKYSMNHEGK 471
P+ V+ L++ +V R + E++ + + W KDG L +Y +GK
Sbjct: 343 EPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGK 402
Query: 472 RAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPA 531
R LI D D G Y V+ +G E A + VEE+ V ++D+ A
Sbjct: 403 RHILIFSDVVQEDRGRYQVIT--NGGQCE----AELIVEEKQLEVLQDIADLTVKASEQA 456
Query: 532 ELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTE 591
++DEKV G W K+G E+ + I G HKL+ + PE EG YTF G
Sbjct: 457 VFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYA 516
Query: 592 SEASVFI------------ADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKV 639
S + +PP I + +AI V G+ + V G+P P
Sbjct: 517 LSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVA 576
Query: 640 TWYK-DGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVL 698
TW K D + T E R +E+ D + I + RED G +K+ N G A++ L V+
Sbjct: 577 TWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVV 636
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKV 758
D P PP+ V + + W+ P +GG+PVT ++VER+ G + W+K+
Sbjct: 637 DVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTE 695
Query: 759 TNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAV 818
T + + K+ EG Y+ R+ AVN+ GVS P + F PI P V DVT
Sbjct: 696 TTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM--PIAPTSEPLHLIVEDVTDTTT 753
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
T+ W P + G + GY+VE +GS WVP N +P++ TV L FRV+
Sbjct: 754 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVG 813
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSI--SLAWREPAEGDPPSGYI 936
VN AG +P+ + V ++ +PP + H+ + + L P +G P +
Sbjct: 814 VNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVV 873
Query: 937 ------------LEMRAE--DTKEWSKCTKIPISGTCYTVGGLIERQK--YFFRIRAVNE 980
+ +R DT + + SG Y + IE K RIR V +
Sbjct: 874 WTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGE-YELSVQIENMKDTATIRIRVVEK 932
Query: 981 AG--VGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRA 1018
AG + V+ G A+ APK D ++ + + V +A
Sbjct: 933 AGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKA 972
Score = 45.8 bits (107), Expect = 3e-04
Identities = 70/300 (23%), Positives = 107/300 (35%), Gaps = 47/300 (15%)
Query: 1036 VIWQKDGVPT------KGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
V+W KDGV K R K + + + D G Y+++ EA +
Sbjct: 376 VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVE 435
Query: 1090 VRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDAS-TATWYTAAER 1148
+ L + +++ + V+ +A + D T WY
Sbjct: 436 EK---------QLEVLQDIADLT---------VKASEQAVFKCEVSDEKVTGKWYKNGVE 477
Query: 1149 VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKD 1208
V +K +T GR + ++V I D P D D + LSAKL E K
Sbjct: 478 VRPSK-RITISHVGR--FHKLV----IDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
Query: 1209 WRHAPRFVTPLKPH------------TVLRGQDCTMTCAFLGNPRPTVTLYKGD-VNITA 1255
+ P+ P K H V+ G + + G P P T KGD V T
Sbjct: 531 -EYVPKQEPP-KIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT 588
Query: 1256 NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASIT 1315
+ + VI + +D G Y++ V N +G+D +S L V D D IT
Sbjct: 589 EGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRIT 648
Score = 33.5 bits (75), Expect = 1.4
Identities = 32/129 (24%), Positives = 54/129 (41%), Gaps = 10/129 (7%)
Query: 1194 IQDLSAKLKPYEKK--DWRHAPRFVTPLKP-HTVLRGQDCTMTCAFLGNPRPTVTLYKGD 1250
I DL LK +K + + + F L P + V RG + + +P T+ +K
Sbjct: 235 ITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVE-ISDPDLTLKWFKNG 293
Query: 1251 VNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSV 1310
I +SK+ + + L I CTL D Y V V++E C ++ K+ +
Sbjct: 294 QEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDE------KCFTELFVKEPPVL 347
Query: 1311 VASITESLQ 1319
+ + E Q
Sbjct: 348 IVTPLEDQQ 356
>gi|46049110 myosin binding protein C, slow type isoform 4 [Homo
sapiens]
Length = 1123
Score = 303 bits (777), Expect = 6e-82
Identities = 246/888 (27%), Positives = 381/888 (42%), Gaps = 46/888 (5%)
Query: 429 RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
+V + R EL + ++W K+GQ + TKY H+G + L I + Q++D EY
Sbjct: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLK 548
V A + TE + V E V + D A G EL ++++ W K
Sbjct: 323 YVTAGDEKCSTELF------VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFK 376
Query: 549 DGKEITDLPG----MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
+G+EI +PG +I +G H LI +Y+ G +S A + + P
Sbjct: 377 NGEEI--IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL- 433
Query: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL 664
+L L TV +G +K K W K+G+ V E +R+ +
Sbjct: 434 --KILTPLTDQ--TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHK 487
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKA 724
L I+N + ED G + D + T + V+D PK ++ K +
Sbjct: 488 LVIANALTEDEGDYVFA--PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 545
Query: 725 PKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGV 784
G P + + R G K+ I E G++ T + I + GV
Sbjct: 546 EIPISGEPPPKAMWSR---GDKA---IMEGSGRIR---TESYPDSSTLVIDIAERDDSGV 596
Query: 785 ------SDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
++ E ++ P P VT+V + + W P DGG+P+LGY +
Sbjct: 597 YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 656
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
ER+KK S+ W+ +N D + T ++E YE R+ AVN G +PS+PS V
Sbjct: 657 ERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLA 716
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPIS 956
PP L L V +++++++ WR P GY+LE E T++W K I
Sbjct: 717 VTSPPTL---LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLID 773
Query: 957 GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVV 1016
T +T+ GL K F R++AVN AG EP + + PK + LK +
Sbjct: 774 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 833
Query: 1017 RAGTALCIHAAFSGSPPPDVIWQKDGVP-TKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
R G A+ + F G P P++ W+KDG K + I S+ + I +RS SG Y +
Sbjct: 834 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDL 893
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
++ + I +++ D P PP +++ + V LTW D Y I K
Sbjct: 894 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 953
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD-SRDTWLINKDQI 1194
D + W+T E T+T L+ G +YYFRV + N G SE ++++ +I +D
Sbjct: 954 DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD-- 1011
Query: 1195 QDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNIT 1254
K YE D+ AP F PL + G + T+ C+ GNP+P +T K V I
Sbjct: 1012 -GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1070
Query: 1255 ANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
+ ++ S GVCTL I + D G Y N+LG C L V
Sbjct: 1071 DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1118
Score = 261 bits (666), Expect = 4e-69
Identities = 229/923 (24%), Positives = 389/923 (42%), Gaps = 132/923 (14%)
Query: 12 EHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGDSVPEFVE 71
E S E + TT + ++ GEE ++ ++S + F+E
Sbjct: 20 EEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSIL-----------------FIE 62
Query: 72 KPQPVTAPEGDKAVFRARVQGN---AKPHISWKRESGIPIKESAKIFYDSINKEHVLKLE 128
KPQ T G+ F A+V+ KP I W + + + A +H+ E
Sbjct: 63 KPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAG--------KHLQLKE 114
Query: 129 PLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANE 188
+ +YT + + + ++ R K K + +
Sbjct: 115 TF--------------ERHSRVYTFEMQIIKAKDNFAGNY----RCEVTYKDKFDSCSFD 156
Query: 189 KEMLEILSKVPKKDFEKVCM-------EYGFTDFRGLL--RKLKEMKKKVEVEAIRILKP 239
E+ E P D + G DF GLL R++K+ +++ +V+ +LK
Sbjct: 157 LEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKN 216
Query: 240 LEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISN 299
+ E + +I + G D++ M +
Sbjct: 217 AKPSEYE-----------------------------KIAFQYGITDLRGMLKR------- 240
Query: 300 VNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFV 359
+ + +K+ +A +LD + V + F + L+ +
Sbjct: 241 -------LKRMRREEKKSAAFAKILDPAYQ---------VDKGGRVRFVVELADPKLEVK 284
Query: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPI 419
W NG+E++ KY G L I + +++D E+ AG+ +L + PI
Sbjct: 285 WYKNGQEIRPSTKY--IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
Query: 420 KFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTK--YSMNHEGKRAELII 477
L++ R LECE++ D ++W K+G+ ++ G K Y + EGK+ LII
Sbjct: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
Query: 478 EDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVL 537
E A +D EY+V+ T S+A ++V+ + + + ++D G E+C+
Sbjct: 403 EGATKADAAEYSVMT------TGGQSSAKLSVDLKPLKILTPLTDQTVNLGK--EICLKC 454
Query: 538 N-DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR--AKGTESEA 594
E + G W K+G + + +++V +G +HKL+ + E EG Y F A A
Sbjct: 455 EISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
Query: 595 SVFIADPPTIDPSVLEALAA-HAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEE- 652
V + DPP I +L+ L A + +TV G+ +++P G+P PK W + + E
Sbjct: 515 KVHVIDPPKI---ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
Query: 653 RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLE 712
R+ E D + L I R+DSG+ + LKN+ G A A++ + V+D P PP E
Sbjct: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTE 630
Query: 713 LSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAY 772
+ M W+ P +GG P+ + +ER+ W+++ K T F K+ EG AY
Sbjct: 631 VGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAY 690
Query: 773 QFRILAVNSEGVSDPLETEEVFAGNPI-EPPGFASQPQVTDVTKEAVTITWNAPTQDGGA 831
+ RI AVN+ G+S P F + PP + VTD T VT+ W P G A
Sbjct: 691 EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT---VTMRWRPPDHIGAA 747
Query: 832 PVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPS 891
+ GY++E +G+ W+ NKD I TK T+ GL D + RV AVN AG +P S
Sbjct: 748 GLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 807
Query: 892 SSVVAKDPVKPPGLVQDLHVSDS 914
++ K+ ++PP + H+ +
Sbjct: 808 QPILVKEIIEPPKIRIPRHLKQT 830
Score = 41.6 bits (96), Expect = 0.005
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 1/95 (1%)
Query: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS-KFWYNSTSGVCTLVIPTCTLKDSG 1281
TV+ G + G P P +GD I S + S TLVI DSG
Sbjct: 536 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 595
Query: 1282 DYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
Y + ++NE G+ +S + V D D V ++TE
Sbjct: 596 VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
Score = 30.8 bits (68), Expect = 9.0
Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 3/124 (2%)
Query: 24 HVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGD--SVPEFVEKPQPVTAPEG 81
+ + FS+ + E+ K S+++ + ++ D P F + A G
Sbjct: 984 YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1043
Query: 82 DKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCI 141
A V+GN KP I+W + + I + + S L++ + D Y C
Sbjct: 1044 YNATLNCSVRGNPKPKITWMKNK-VAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1102
Query: 142 ASND 145
A ND
Sbjct: 1103 AVND 1106
>gi|46049125 myosin binding protein C, slow type isoform 2 [Homo
sapiens]
Length = 1148
Score = 303 bits (777), Expect = 6e-82
Identities = 246/888 (27%), Positives = 381/888 (42%), Gaps = 46/888 (5%)
Query: 429 RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
+V + R EL + ++W K+GQ + TKY H+G + L I + Q++D EY
Sbjct: 288 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLK 548
V A + TE + V E V + D A G EL ++++ W K
Sbjct: 348 YVTAGDEKCSTELF------VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFK 401
Query: 549 DGKEITDLPG----MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
+G+EI +PG +I +G H LI +Y+ G +S A + + P
Sbjct: 402 NGEEI--IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL- 458
Query: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL 664
+L L TV +G +K K W K+G+ V E +R+ +
Sbjct: 459 --KILTPLTDQ--TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHK 512
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKA 724
L I+N + ED G + D + T + V+D PK ++ K +
Sbjct: 513 LVIANALTEDEGDYVFA--PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 570
Query: 725 PKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGV 784
G P + + R G K+ I E G++ T + I + GV
Sbjct: 571 EIPISGEPPPKAMWSR---GDKA---IMEGSGRIR---TESYPDSSTLVIDIAERDDSGV 621
Query: 785 ------SDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
++ E ++ P P VT+V + + W P DGG+P+LGY +
Sbjct: 622 YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 681
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
ER+KK S+ W+ +N D + T ++E YE R+ AVN G +PS+PS V
Sbjct: 682 ERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLA 741
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPIS 956
PP L L V +++++++ WR P GY+LE E T++W K I
Sbjct: 742 VTSPPTL---LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLID 798
Query: 957 GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVV 1016
T +T+ GL K F R++AVN AG EP + + PK + LK +
Sbjct: 799 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 858
Query: 1017 RAGTALCIHAAFSGSPPPDVIWQKDGVP-TKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
R G A+ + F G P P++ W+KDG K + I S+ + I +RS SG Y +
Sbjct: 859 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDL 918
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
++ + I +++ D P PP +++ + V LTW D Y I K
Sbjct: 919 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD-SRDTWLINKDQI 1194
D + W+T E T+T L+ G +YYFRV + N G SE ++++ +I +D
Sbjct: 979 DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD-- 1036
Query: 1195 QDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNIT 1254
K YE D+ AP F PL + G + T+ C+ GNP+P +T K V I
Sbjct: 1037 -GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
Query: 1255 ANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
+ ++ S GVCTL I + D G Y N+LG C L V
Sbjct: 1096 DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
Score = 260 bits (664), Expect = 7e-69
Identities = 173/576 (30%), Positives = 280/576 (48%), Gaps = 25/576 (4%)
Query: 347 FEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
F + L+ + W NG+E++ KY G L I + +++D E+ AG+
Sbjct: 297 FVVELADPKLEVKWYKNGQEIRPSTKY--IFEHKGCQRILFINNCQMTDDSEYYVTAGDE 354
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTK--Y 464
+L + PI L++ R LECE++ D ++W K+G+ ++ G K Y
Sbjct: 355 KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 414
Query: 465 SMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524
+ EGK+ LIIE A +D EY+V+ T S+A ++V+ + + + ++D
Sbjct: 415 RIRVEGKKHILIIEGATKADAAEYSVMT------TGGQSSAKLSVDLKPLKILTPLTDQT 468
Query: 525 AATGSPAELCVVLN-DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKY 583
G E+C+ E + G W K+G + + +++V +G +HKL+ + E EG Y
Sbjct: 469 VNLGK--EICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
Query: 584 TFR--AKGTESEASVFIADPPTIDPSVLEALAA-HAITVKVGHTAHIKVPFRGKPLPKVT 640
F A A V + DPP I +L+ L A + +TV G+ +++P G+P PK
Sbjct: 527 VFAPDAYNVTLPAKVHVIDPPKI---ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 583
Query: 641 WYKDGMEVTEEE-RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLD 699
W + + E R+ E D + L I R+DSG+ + LKN+ G A A++ + V+D
Sbjct: 584 WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
Query: 700 RPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVT 759
P PP E+ M W+ P +GG P+ + +ER+ W+++ K T
Sbjct: 644 FPDPPVAPT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET 702
Query: 760 NFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPI-EPPGFASQPQVTDVTKEAV 818
F K+ EG AY+ RI AVN+ G+S P F + PP + VTD T V
Sbjct: 703 TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT---V 759
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
T+ W P G A + GY++E +G+ W+ NKD I TK T+ GL D + RV A
Sbjct: 760 TMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 819
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDS 914
VN AG +P S ++ K+ ++PP + H+ +
Sbjct: 820 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 855
Score = 157 bits (397), Expect = 6e-38
Identities = 142/589 (24%), Positives = 261/589 (44%), Gaps = 65/589 (11%)
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGN---AKPHISWKRESGIPIKESA------KIFYDSI 119
F+EKPQ T G+ F A+V+ KP I W + + + A K ++
Sbjct: 85 FIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERH 144
Query: 120 NKEHVLKLEPLTSDDS--DNYKC-IASNDHADA------------------IYTVSLLVT 158
++ + +++ + + D+ NY+C + D D+ I +
Sbjct: 145 SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSG 204
Query: 159 EGQE---KMDFKKMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDF 215
EGQE ++DF +LK+R + KQ++ + ++ E+L ++EK+ +YG TD
Sbjct: 205 EGQEDAGELDFSGLLKRR-----EVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDL 259
Query: 216 RGLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPL 275
RG+L++LK M+++ + A + D +VD ++EL DP +++ W K + +
Sbjct: 260 RGMLKRLKRMRREEKKSAA--FAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEI 317
Query: 276 RIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMK 335
R KY + G + +L I+N M D Y ++ GD++ S EL V + P+ +++
Sbjct: 318 RPST---KYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLE 374
Query: 336 PVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSD 395
+ E +S+ + N W NG+E+ K + +G H L I+ A +D
Sbjct: 375 DTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKAD 434
Query: 396 SGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDG 455
+ E+S A+L++D P+K ++ L + V CL+CE+ S+++ +W K+G
Sbjct: 435 AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPGKWTKNG 493
Query: 456 QLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYST--AIVTVEERL 513
+ + + H+G+ +L+I +A D G+Y P Y T A V V +
Sbjct: 494 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFA------PDAYNVTLPAKVHVIDPP 547
Query: 514 ATVKSGM---SDVHAATGSPAELCVVLNDE-KVEGVWLKDGKEITDLPG-MQIVKQGAVH 568
+ G+ + V G+ L + ++ E + +W + K I + G ++
Sbjct: 548 KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSS 607
Query: 569 KLIFPSMGPEHEGKYTFRAKGTESEASVFI-------ADPPTIDPSVLE 610
L+ + G Y K EA I DPP + P+V E
Sbjct: 608 TLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPP-VAPTVTE 655
Score = 41.6 bits (96), Expect = 0.005
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 1/95 (1%)
Query: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS-KFWYNSTSGVCTLVIPTCTLKDSG 1281
TV+ G + G P P +GD I S + S TLVI DSG
Sbjct: 561 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 620
Query: 1282 DYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
Y + ++NE G+ +S + V D D V ++TE
Sbjct: 621 VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
Score = 30.8 bits (68), Expect = 9.0
Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 3/124 (2%)
Query: 24 HVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGD--SVPEFVEKPQPVTAPEG 81
+ + FS+ + E+ K S+++ + ++ D P F + A G
Sbjct: 1009 YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1068
Query: 82 DKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCI 141
A V+GN KP I+W + + I + + S L++ + D Y C
Sbjct: 1069 YNATLNCSVRGNPKPKITWMKNK-VAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1127
Query: 142 ASND 145
A ND
Sbjct: 1128 AVND 1131
>gi|45976288 myosin binding protein C, slow type isoform 1 [Homo
sapiens]
Length = 1171
Score = 303 bits (777), Expect = 6e-82
Identities = 246/888 (27%), Positives = 381/888 (42%), Gaps = 46/888 (5%)
Query: 429 RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
+V + R EL + ++W K+GQ + TKY H+G + L I + Q++D EY
Sbjct: 288 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLK 548
V A + TE + V E V + D A G EL ++++ W K
Sbjct: 348 YVTAGDEKCSTELF------VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFK 401
Query: 549 DGKEITDLPG----MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
+G+EI +PG +I +G H LI +Y+ G +S A + + P
Sbjct: 402 NGEEI--IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL- 458
Query: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL 664
+L L TV +G +K K W K+G+ V E +R+ +
Sbjct: 459 --KILTPLTDQ--TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHK 512
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKA 724
L I+N + ED G + D + T + V+D PK ++ K +
Sbjct: 513 LVIANALTEDEGDYVFA--PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 570
Query: 725 PKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGV 784
G P + + R G K+ I E G++ T + I + GV
Sbjct: 571 EIPISGEPPPKAMWSR---GDKA---IMEGSGRIR---TESYPDSSTLVIDIAERDDSGV 621
Query: 785 ------SDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
++ E ++ P P VT+V + + W P DGG+P+LGY +
Sbjct: 622 YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 681
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
ER+KK S+ W+ +N D + T ++E YE R+ AVN G +PS+PS V
Sbjct: 682 ERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLA 741
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPIS 956
PP L L V +++++++ WR P GY+LE E T++W K I
Sbjct: 742 VTSPPTL---LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLID 798
Query: 957 GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVV 1016
T +T+ GL K F R++AVN AG EP + + PK + LK +
Sbjct: 799 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 858
Query: 1017 RAGTALCIHAAFSGSPPPDVIWQKDGVP-TKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
R G A+ + F G P P++ W+KDG K + I S+ + I +RS SG Y +
Sbjct: 859 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDL 918
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
++ + I +++ D P PP +++ + V LTW D Y I K
Sbjct: 919 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD-SRDTWLINKDQI 1194
D + W+T E T+T L+ G +YYFRV + N G SE ++++ +I +D
Sbjct: 979 DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD-- 1036
Query: 1195 QDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNIT 1254
K YE D+ AP F PL + G + T+ C+ GNP+P +T K V I
Sbjct: 1037 -GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
Query: 1255 ANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
+ ++ S GVCTL I + D G Y N+LG C L V
Sbjct: 1096 DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
Score = 260 bits (664), Expect = 7e-69
Identities = 173/576 (30%), Positives = 280/576 (48%), Gaps = 25/576 (4%)
Query: 347 FEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
F + L+ + W NG+E++ KY G L I + +++D E+ AG+
Sbjct: 297 FVVELADPKLEVKWYKNGQEIRPSTKY--IFEHKGCQRILFINNCQMTDDSEYYVTAGDE 354
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTK--Y 464
+L + PI L++ R LECE++ D ++W K+G+ ++ G K Y
Sbjct: 355 KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 414
Query: 465 SMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524
+ EGK+ LIIE A +D EY+V+ T S+A ++V+ + + + ++D
Sbjct: 415 RIRVEGKKHILIIEGATKADAAEYSVMT------TGGQSSAKLSVDLKPLKILTPLTDQT 468
Query: 525 AATGSPAELCVVLN-DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKY 583
G E+C+ E + G W K+G + + +++V +G +HKL+ + E EG Y
Sbjct: 469 VNLGK--EICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
Query: 584 TFR--AKGTESEASVFIADPPTIDPSVLEALAA-HAITVKVGHTAHIKVPFRGKPLPKVT 640
F A A V + DPP I +L+ L A + +TV G+ +++P G+P PK
Sbjct: 527 VFAPDAYNVTLPAKVHVIDPPKI---ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 583
Query: 641 WYKDGMEVTEEE-RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLD 699
W + + E R+ E D + L I R+DSG+ + LKN+ G A A++ + V+D
Sbjct: 584 WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
Query: 700 RPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVT 759
P PP E+ M W+ P +GG P+ + +ER+ W+++ K T
Sbjct: 644 FPDPPVAPT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET 702
Query: 760 NFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPI-EPPGFASQPQVTDVTKEAV 818
F K+ EG AY+ RI AVN+ G+S P F + PP + VTD T V
Sbjct: 703 TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT---V 759
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
T+ W P G A + GY++E +G+ W+ NKD I TK T+ GL D + RV A
Sbjct: 760 TMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 819
Query: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDS 914
VN AG +P S ++ K+ ++PP + H+ +
Sbjct: 820 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 855
Score = 157 bits (397), Expect = 6e-38
Identities = 142/589 (24%), Positives = 261/589 (44%), Gaps = 65/589 (11%)
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGN---AKPHISWKRESGIPIKESA------KIFYDSI 119
F+EKPQ T G+ F A+V+ KP I W + + + A K ++
Sbjct: 85 FIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERH 144
Query: 120 NKEHVLKLEPLTSDDS--DNYKC-IASNDHADA------------------IYTVSLLVT 158
++ + +++ + + D+ NY+C + D D+ I +
Sbjct: 145 SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSG 204
Query: 159 EGQE---KMDFKKMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDF 215
EGQE ++DF +LK+R + KQ++ + ++ E+L ++EK+ +YG TD
Sbjct: 205 EGQEDAGELDFSGLLKRR-----EVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDL 259
Query: 216 RGLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPL 275
RG+L++LK M+++ + A + D +VD ++EL DP +++ W K + +
Sbjct: 260 RGMLKRLKRMRREEKKSAA--FAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEI 317
Query: 276 RIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMK 335
R KY + G + +L I+N M D Y ++ GD++ S EL V + P+ +++
Sbjct: 318 RPST---KYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLE 374
Query: 336 PVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSD 395
+ E +S+ + N W NG+E+ K + +G H L I+ A +D
Sbjct: 375 DTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKAD 434
Query: 396 SGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDG 455
+ E+S A+L++D P+K ++ L + V CL+CE+ S+++ +W K+G
Sbjct: 435 AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPGKWTKNG 493
Query: 456 QLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYST--AIVTVEERL 513
+ + + H+G+ +L+I +A D G+Y P Y T A V V +
Sbjct: 494 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFA------PDAYNVTLPAKVHVIDPP 547
Query: 514 ATVKSGM---SDVHAATGSPAELCVVLNDE-KVEGVWLKDGKEITDLPG-MQIVKQGAVH 568
+ G+ + V G+ L + ++ E + +W + K I + G ++
Sbjct: 548 KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSS 607
Query: 569 KLIFPSMGPEHEGKYTFRAKGTESEASVFI-------ADPPTIDPSVLE 610
L+ + G Y K EA I DPP + P+V E
Sbjct: 608 TLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPP-VAPTVTE 655
Score = 42.7 bits (99), Expect = 0.002
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLK 681
G+ A + RG P PK+TW K+ + + ++ R M + L I D G K
Sbjct: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1127
Query: 682 LKNDHGSA--TATLHLSVLDRPKPPQGRVEFLELSGSCVHMK 721
ND G+ L + V+ + G+ FLE +H K
Sbjct: 1128 AVNDLGTVEIECKLEVKVIYQGVNTPGQPVFLEGQQQSLHNK 1169
Score = 41.6 bits (96), Expect = 0.005
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 1/95 (1%)
Query: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS-KFWYNSTSGVCTLVIPTCTLKDSG 1281
TV+ G + G P P +GD I S + S TLVI DSG
Sbjct: 561 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 620
Query: 1282 DYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
Y + ++NE G+ +S + V D D V ++TE
Sbjct: 621 VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
Score = 30.8 bits (68), Expect = 9.0
Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 3/124 (2%)
Query: 24 HVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGD--SVPEFVEKPQPVTAPEG 81
+ + FS+ + E+ K S+++ + ++ D P F + A G
Sbjct: 1009 YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1068
Query: 82 DKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCI 141
A V+GN KP I+W + + I + + S L++ + D Y C
Sbjct: 1069 YNATLNCSVRGNPKPKITWMKNK-VAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1127
Query: 142 ASND 145
A ND
Sbjct: 1128 AVND 1131
>gi|46049119 myosin binding protein C, slow type isoform 3 [Homo
sapiens]
Length = 1141
Score = 291 bits (744), Expect = 4e-78
Identities = 245/906 (27%), Positives = 381/906 (42%), Gaps = 64/906 (7%)
Query: 429 RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
+V + R EL + ++W K+GQ + TKY H+G + L I + Q++D EY
Sbjct: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLK 548
V A + TE + V E V + D A G EL ++++ W K
Sbjct: 323 YVTAGDEKCSTELF------VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFK 376
Query: 549 DGKEITDLPG----MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
+G+EI +PG +I +G H LI +Y+ G +S A + + P
Sbjct: 377 NGEEI--IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL- 433
Query: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL 664
+L L TV +G +K K W K+G+ V E +R+ +
Sbjct: 434 --KILTPLTDQ--TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHK 487
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKA 724
L I+N + ED G + D + T + V+D PK ++ K +
Sbjct: 488 LVIANALTEDEGDYVFA--PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 545
Query: 725 PKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGV 784
G P + + R G K+ I E G++ T + I + GV
Sbjct: 546 EIPISGEPPPKAMWSR---GDKA---IMEGSGRIR---TESYPDSSTLVIDIAERDDSGV 596
Query: 785 ------SDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
++ E ++ P P VT+V + + W P DGG+P+LGY +
Sbjct: 597 YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 656
Query: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
ER+KK S+ W+ +N D + T ++E YE R+ AVN G +PS+PS V
Sbjct: 657 ERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLA 716
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDT------------ 944
PP L L V +++++++ WR P GY+LE E +
Sbjct: 717 VTSPPTL---LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEA 773
Query: 945 ------KEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPP 998
++W K I T +T+ GL K F R++AVN AG EP + +
Sbjct: 774 AYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 833
Query: 999 PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-TKGRETITKSKNH 1057
PK + LK + R G A+ + F G P P++ W+KDG K + I S+
Sbjct: 834 IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 893
Query: 1058 SQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWN 1117
+ I +RS SG Y + ++ + I +++ D P PP +++ + V LTW
Sbjct: 894 TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 953
Query: 1118 HSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGD 1177
D Y I K D + W+T E T+T L+ G +YYFRV + N G
Sbjct: 954 PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1013
Query: 1178 SEPLD-SRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAF 1236
SE ++++ +I +D K YE D+ AP F PL + G + T+ C+
Sbjct: 1014 SEDATMTKESAVIARD---GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSV 1070
Query: 1237 LGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRS 1296
GNP+P +T K V I + ++ S GVCTL I + D G Y N+LG
Sbjct: 1071 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1130
Query: 1297 SCTLTV 1302
C L V
Sbjct: 1131 ECKLEV 1136
Score = 251 bits (642), Expect = 2e-66
Identities = 230/941 (24%), Positives = 389/941 (41%), Gaps = 150/941 (15%)
Query: 12 EHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGDSVPEFVE 71
E S E + TT + ++ GEE ++ ++S + F+E
Sbjct: 20 EEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSIL-----------------FIE 62
Query: 72 KPQPVTAPEGDKAVFRARVQGN---AKPHISWKRESGIPIKESAKIFYDSINKEHVLKLE 128
KPQ T G+ F A+V+ KP I W + + + A +H+ E
Sbjct: 63 KPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAG--------KHLQLKE 114
Query: 129 PLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANE 188
+ +YT + + + ++ R K K + +
Sbjct: 115 TF--------------ERHSRVYTFEMQIIKAKDNFAGNY----RCEVTYKDKFDSCSFD 156
Query: 189 KEMLEILSKVPKKDFEKVCM-------EYGFTDFRGLL--RKLKEMKKKVEVEAIRILKP 239
E+ E P D + G DF GLL R++K+ +++ +V+ +LK
Sbjct: 157 LEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKN 216
Query: 240 LEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISN 299
+ E + +I + G D++ M +
Sbjct: 217 AKPSEYE-----------------------------KIAFQYGITDLRGMLKR------- 240
Query: 300 VNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFV 359
+ + +K+ +A +LD + V + F + L+ +
Sbjct: 241 -------LKRMRREEKKSAAFAKILDPAYQ---------VDKGGRVRFVVELADPKLEVK 284
Query: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPI 419
W NG+E++ KY G L I + +++D E+ AG+ +L + PI
Sbjct: 285 WYKNGQEIRPSTKY--IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
Query: 420 KFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTK--YSMNHEGKRAELII 477
L++ R LECE++ D ++W K+G+ ++ G K Y + EGK+ LII
Sbjct: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
Query: 478 EDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVL 537
E A +D EY+V+ T S+A ++V+ + + + ++D G E+C+
Sbjct: 403 EGATKADAAEYSVMT------TGGQSSAKLSVDLKPLKILTPLTDQTVNLGK--EICLKC 454
Query: 538 N-DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR--AKGTESEA 594
E + G W K+G + + +++V +G +HKL+ + E EG Y F A A
Sbjct: 455 EISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
Query: 595 SVFIADPPTIDPSVLEALAA-HAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEE- 652
V + DPP I +L+ L A + +TV G+ +++P G+P PK W + + E
Sbjct: 515 KVHVIDPPKI---ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
Query: 653 RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLE 712
R+ E D + L I R+DSG+ + LKN+ G A A++ + V+D P PP E
Sbjct: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTE 630
Query: 713 LSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAY 772
+ M W+ P +GG P+ + +ER+ W+++ K T F K+ EG AY
Sbjct: 631 VGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAY 690
Query: 773 QFRILAVNSEGVSDPLETEEVFAGNPI-EPPGFASQPQVTDVTKEAVTITWNAPTQDGGA 831
+ RI AVN+ G+S P F + PP + VTD T VT+ W P G A
Sbjct: 691 EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT---VTMRWRPPDHIGAA 747
Query: 832 PVLGYIVERRKKGSNL------------------WVPVNKDPIQGTKCTVDGLLEDTEYE 873
+ GY++E +GS W+ NKD I TK T+ GL D +
Sbjct: 748 GLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIF 807
Query: 874 FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDS 914
RV AVN AG +P S ++ K+ ++PP + H+ +
Sbjct: 808 VRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 848
Score = 41.6 bits (96), Expect = 0.005
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 1/95 (1%)
Query: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS-KFWYNSTSGVCTLVIPTCTLKDSG 1281
TV+ G + G P P +GD I S + S TLVI DSG
Sbjct: 536 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 595
Query: 1282 DYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
Y + ++NE G+ +S + V D D V ++TE
Sbjct: 596 VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
Score = 30.8 bits (68), Expect = 9.0
Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 3/124 (2%)
Query: 24 HVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGD--SVPEFVEKPQPVTAPEG 81
+ + FS+ + E+ K S+++ + ++ D P F + A G
Sbjct: 1002 YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1061
Query: 82 DKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCI 141
A V+GN KP I+W + + I + + S L++ + D Y C
Sbjct: 1062 YNATLNCSVRGNPKPKITWMKNK-VAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
Query: 142 ASND 145
A ND
Sbjct: 1121 AVND 1124
>gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
Length = 1274
Score = 278 bits (711), Expect = 2e-74
Identities = 317/1322 (23%), Positives = 518/1322 (39%), Gaps = 135/1322 (10%)
Query: 61 PAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSIN 120
P V F +KP+ V G AVF A + A + W+R G I S K +
Sbjct: 4 PGKKPVSAFSKKPRSVEVAAGSPAVFEAETE-RAGVKVRWQR-GGSDISASNKYGLATEG 61
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK 180
H L + + D +Y IA + + + ++ E E M A AP +
Sbjct: 62 TRHTLTVREVGPADQGSYAVIAGSSKVK--FDLKVIEAEKAEPMLAPAPAPAEATGAPGE 119
Query: 181 KQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPL 240
A E+ P G T + + +++P
Sbjct: 120 APAPAA------ELGESAPSPKGSSSAALNGPTP-----------GAPDDPIGLFVMRP- 161
Query: 241 EDKETKVDTTVVFDCIME----LKDPNVKMIWIKGTE---PLRIQYSLGKYDVKQMGTK- 292
+D E V ++ F + LK P VK W KG ++ L +D +K
Sbjct: 162 QDGEVTVGGSITFSARVAGASLLKPPVVK--WFKGKWVDLSSKVGQHLQLHDSYDRASKV 219
Query: 293 -----------------YMLVISNVNMNDAGIYSLSVGDKRMSAELTVLD--EPLKFLGE 333
Y +S + D ++L+V + + +L +L G
Sbjct: 220 YLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGG 279
Query: 334 MKPVKVTERQTAVFEIR-LSKKEPNFVWKFNGKELKRDDKYEITVSEDG---LTHTLKIK 389
+ + + T + + L KK +F RD K E ED L +
Sbjct: 280 GRRISDSHEDTGILDFSSLLKKRDSF-------RTPRDSKLEAPAEEDVWEILRQAPPSE 332
Query: 390 DARLSDSGEFSAEAGNLVQ-KAQLTIDRIPIKFVSNLKNV-RVKERSRACLECELTSKDV 447
R++ + G L + K ++ F L+ +V + + L EL D
Sbjct: 333 YERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDA 392
Query: 448 TLRWKKDGQ-LLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAI 506
++W K+GQ + M G+KY G + L I L+D Y V + TE +
Sbjct: 393 EVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELF---- 448
Query: 507 VTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEIT--DLPGMQIVKQ 564
V+E + + D G E +++E + WLKDG E+T + + K
Sbjct: 449 --VKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKD 506
Query: 565 GAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHT 624
G H LI E G Y G ++ A + + + V +++A + K
Sbjct: 507 GQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKL---EVYQSIADLMVGAK--DQ 561
Query: 625 AHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKN 684
A K + + V W K+G E+ + R+ + LTI + D +
Sbjct: 562 AVFKCEVSDENVRGV-WLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEG 620
Query: 685 DHGSATATLH-----LSVLDRPKPPQ------GRVEFLELSGSCVHMKWKAPKDNGGRPV 733
+ +A LH + + R +PP+ GR+ + + ++ P P
Sbjct: 621 FACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPT 680
Query: 734 TQFIVERRAV--GKKS-----------------WI----KIGEVDGKVTNFSTNK----- 765
++ ++A+ G K+ W+ + E +G+V +T
Sbjct: 681 ---VIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFT 737
Query: 766 VEEGKAYQFRILAVNSEGVSDPLETEEV-FAGNPIEPPGFASQPQVTDVTKEAVTITWNA 824
VE + + V V +P+ ++V I+ P + P++++V +++ T+ W
Sbjct: 738 VEGAEKEDEGVYTVT---VKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEP 794
Query: 825 PTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGP 884
P DGG P+LGYI+ER+KK S W+ +N D IQ ++E YE RV AVN G
Sbjct: 795 PAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGM 854
Query: 885 GQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAE 942
+PS S + P+ PP L V D S++++SL WR P GY +E E
Sbjct: 855 SRPSPASQPFM---PIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPE 911
Query: 943 DTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAP 1002
EW + T V L + FR+RA N AG G PV + V P
Sbjct: 912 GCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRP 971
Query: 1003 KFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE-TITKSKNHSQFL 1061
+ L L+ + + G + + F G P P V W K+G P G E +I S +
Sbjct: 972 RLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILF 1031
Query: 1062 INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD 1121
I + +R SG Y++ ++ E E + + ++V D P PP +LR+ + V L W D
Sbjct: 1032 IRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQD 1091
Query: 1122 VQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE-P 1180
V Y + K D T W+T E V L+ G YYFRV ++N +G S+
Sbjct: 1092 VGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRA 1151
Query: 1181 LDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNP 1240
+++ I + I + + Y+ D+ AP F PL +V+ G + CA G+P
Sbjct: 1152 ATTKEPVFIPRPGI---TYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP 1208
Query: 1241 RPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
+P ++ +K +++ +++F S GV TL I D G Y N G+ R C L
Sbjct: 1209 KPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRL 1268
Query: 1301 TV 1302
V
Sbjct: 1269 EV 1270
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 201 bits (512), Expect = 3e-51
Identities = 144/532 (27%), Positives = 249/532 (46%), Gaps = 31/532 (5%)
Query: 168 KMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKK 227
K K P K + V+ K +L + D + +T G L E K
Sbjct: 2826 KWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGE------YTAVVGQL----ECKA 2875
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K+ VE + I K +++ E T F+C E+ NV +W+K + + K+ +
Sbjct: 2876 KLFVETLHITKTMKNIEVPETKTASFEC--EVSHFNVPSMWLKNGVEIEMSE---KFKIV 2930
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G + L+I N + D+ Y+ G+ ++SA LTV P+ +K + E+ T F
Sbjct: 2931 VQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVT--PIMITSMLKDINAEEKDTITF 2988
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E+ ++ + ++ W NG E+K DK ++ + LTH+L I++ D+ +++ AG
Sbjct: 2989 EVTVNYEGISYKWLKNGVEIKSTDKCQMRTKK--LTHSLNIRNVHFGDAADYTFVAGKAT 3046
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A L ++ I+F ++K+++V E+ RA ECE++ D+T++W KD Q L + +
Sbjct: 3047 STATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQ 3106
Query: 468 HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT 527
E L+I ++SD G+YTVVA + STA + VE R ++S +V
Sbjct: 3107 KEKYVHRLLIPSTRMSDAGKYTVVAGGN------VSTAKLFVEGRDVRIRSIKKEVQVIE 3160
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEIT--DLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A + +N++ V+ W KDG EI + V + +H++ G+YTF
Sbjct: 3161 KQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTF 3220
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
A S ++++ P P VL+ L +TV+ G A G+P PK++WYK+
Sbjct: 3221 VAGRNRSSVTLYVNAPE--PPQVLQEL--QPVTVQSGKPARFCAVISGRPQPKISWYKEE 3276
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
++ + + L + ED+ + + KND+G AT + LSV
Sbjct: 3277 QLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3328
Score = 154 bits (389), Expect = 5e-37
Identities = 157/664 (23%), Positives = 267/664 (40%), Gaps = 60/664 (9%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+ ++KP+ VTA E F V + P + W +S + IK S K S K H L L
Sbjct: 2796 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKS-VEIKPSDKHRLVSERKVHKLML 2853
Query: 128 EPLTSDDSDNYKCIASNDHADA-IYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVA 186
+ ++ D+ Y + A ++ +L +T+ + ++ P+ K
Sbjct: 2854 QNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKNIE-----------VPETKTASFE 2902
Query: 187 NEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVE---------------- 230
E + S K E E +G L +L M E
Sbjct: 2903 CEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSA 2962
Query: 231 ---VEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
V I I L+D + T+ F+ + + + K W+K ++ S K ++
Sbjct: 2963 TLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYK--WLKNGVEIK---STDKCQMR 3017
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+ L I NV+ DA Y+ G +A L V ++F +K +KV E++ A+F
Sbjct: 3018 TKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMF 3077
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E +S+ + W + +EL+ D+ I + ++ H L I R+SD+G+++ AG V
Sbjct: 3078 ECEVSEPDITVQWMKDDQELQITDR--IKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNV 3135
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A+L ++ ++ S K V+V E+ RA +E E+ DV W KDG + +
Sbjct: 3136 STAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3195
Query: 468 H--EGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA 525
+ E + + I + + SD GEYT VA ++ Y A V + V
Sbjct: 3196 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNA-----PEPPQVLQELQPVTV 3250
Query: 526 ATGSPAELCVVLNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
+G PA C V++ + W K+ + ++ + + G + L+ PE YT
Sbjct: 3251 QSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYT 3310
Query: 585 FRAKG----TESEASVFIADPPTIDPSVLEALAAHAITVKV-------GHTAHIKVPFRG 633
AK + AS+ + P + P + AI + G A + G
Sbjct: 3311 CEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG 3370
Query: 634 KPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
L KV+WY ++ M + ED L I+ ED G N G ++T
Sbjct: 3371 TDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTA 3429
Query: 694 HLSV 697
+LS+
Sbjct: 3430 NLSL 3433
Score = 143 bits (361), Expect = 1e-33
Identities = 192/826 (23%), Positives = 330/826 (39%), Gaps = 134/826 (16%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA-KIFYDSINKEHVL 125
P+ V P+PV EG+ A FR RV G +P ++W + K ++ YD I H L
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGI---HYL 1897
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPK------ 179
+ S D+ K A N + V L E Q++ DF+ +L++ P P+
Sbjct: 1898 DIVDCKSYDTGEVKVTAENPEGVIEHKVKL---EIQQREDFRSVLRRAPEPRPEFHVHEP 1954
Query: 180 -------------------------KKQKKVANEK---EMLEILSKVPKKDFEKVCMEYG 211
K+ +++ +EK E E+ SK ++ E
Sbjct: 1955 GKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAIT 2014
Query: 212 FTDFRGLLR--KLKEMKKKVEVEAIRILKPLEDKETK----------------------- 246
+ + + +E+ +K + E + K L ++E K
Sbjct: 2015 AVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPS 2074
Query: 247 VDTTVVFDCIME---------------LKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGT 291
++ +F+ I + P+ + W K ++I+ S Y
Sbjct: 2075 MEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNG--VKIERSDRIYWYWPEDN 2132
Query: 292 KYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPL-KFLGEMKPVKVTERQT-A 345
LVI +V D+ + G+ A L V + L F E++ V E+ T A
Sbjct: 2133 VCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2192
Query: 346 VFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSA---E 402
FE S+ W +G E+ DKY + D H L I SD+ ++S E
Sbjct: 2193 TFECETSEPFVKVKWYKDGMEVHEGDKYRM--HSDRKVHFLSILTIDTSDAEDYSCVLVE 2250
Query: 403 AGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGT 462
N+ A+L ++ ++FV L+++ V E LEC ++ +++ +W + L
Sbjct: 2251 DENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNG 2310
Query: 463 KYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSD 522
KY++ R L ++D D GEY+ V DG T T + ++ R + G+SD
Sbjct: 2311 KYTITSRRGRQNLTVKDVTKEDQGEYSFVI--DGKKT----TCKLKMKPRPIAILQGLSD 2364
Query: 523 VHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGK 582
G +L V ++ E VEGVW+KDG+E+ + IV H L+ M E G
Sbjct: 2365 QKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGN 2424
Query: 583 YTFR----AKGTESEASVFIAD--PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPL 636
Y+F T SV+ D P D +V+E K + VP +
Sbjct: 2425 YSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEG-------TKAVLECKVSVP----DV 2473
Query: 637 PKVTWYKDGMEVTEEERV-SMERGEDQALLTISNCVREDSG---LILLKLKNDHGSATAT 692
V WY + ++ ++RV ++ +G Q L+ I+ D G LI+ +++ + +
Sbjct: 2474 TSVKWYLNDEQIKPDDRVQAIVKGTKQRLV-INRTHASDEGPYKLIVGRVETNCNLSVEK 2532
Query: 693 LHL--SVLDRPKPPQGRVEF-LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI 749
+ + + D V F +ELS S + + W KD +P +++ +E K +
Sbjct: 2533 IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNF-KDKEIKPSSKYKIEAHGKIYKLTV 2591
Query: 750 --KIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEV 793
+ + +GK T ++ + GK L V +S PL + V
Sbjct: 2592 LNMMKDDEGKYTFYAGENMTSGK------LTVAGGAISKPLTDQTV 2631
Score = 130 bits (326), Expect = 1e-29
Identities = 117/443 (26%), Positives = 200/443 (45%), Gaps = 28/443 (6%)
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K+ V I KPL D+ VF+C E+ +P+ K W++ + L + ++ +
Sbjct: 2614 KLTVAGGAISKPLTDQTVAESQEAVFEC--EVANPDSKGEWLRDGKHLPLTNNIRS---E 2668
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G K L+I+ ++D G Y+ V + SA+L V E +K +K + VTE Q AVF
Sbjct: 2669 SDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKV--EAVKIKKTLKNLTVTETQDAVF 2726
Query: 348 EIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+ L+ V W NG L+ ++KY I+V G ++L+IK+ + D + G L
Sbjct: 2727 TVELTHPNVKGVQWIKNGVVLESNEKYAISVK--GTIYSLRIKNCAIVDESVYGFRLGRL 2784
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
A+L ++ + K + K+V E + E ++ V ++W + K+ +
Sbjct: 2785 GASARLHVETV--KIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRL 2842
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
E K +L++++ SD GEYT V Q E + V E L K+ M ++
Sbjct: 2843 VSERKVHKLMLQNISPSDAGEYTAVVGQ----LECKAKLFV---ETLHITKT-MKNIEVP 2894
Query: 527 TGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
A ++ V +WLK+G EI +IV QG +H+LI + E +YTF
Sbjct: 2895 ETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV 2954
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
+ A++ + P + S+L+ + A K T + V + G W K+G+
Sbjct: 2955 CGNDQVSATLTVT--PIMITSMLKDINAEE---KDTITFEVTVNYEG---ISYKWLKNGV 3006
Query: 647 EVTEEERVSMERGEDQALLTISN 669
E+ ++ M + L I N
Sbjct: 3007 EIKSTDKCQMRTKKLTHSLNIRN 3029
Score = 121 bits (303), Expect = 5e-27
Identities = 146/660 (22%), Positives = 265/660 (40%), Gaps = 56/660 (8%)
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLE 128
F ++ Q V A E D + W ++ G+ + E K S K H L +
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKD-GMEVHEGDKYRMHSDRKVHFLSIL 2234
Query: 129 PLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANE 188
+ + D+++Y C+ D + + T + L+ EG ++F K L+ P + +
Sbjct: 2235 TIDTSDAEDYSCVLVED--ENVKTTAKLIVEG-AVVEFVKELQDIEVPESYSGELECIVS 2291
Query: 189 KEMLEILSKVPKKDFE-KVCMEYGFTDFRG--------------------LLRKLKEMKK 227
E +E K D E K +Y T RG + K K
Sbjct: 2292 PENIE--GKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTCKL 2349
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
K++ I IL+ L D++ V + + L+ +V+ +W+K + ++ + K
Sbjct: 2350 KMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE--SVEGVWMKDGQEVQPSDRVHIVIDK 2407
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
Q +ML+I ++ DAG YS ++ +S V + + +K V V E AV
Sbjct: 2408 Q---SHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVL 2464
Query: 348 EIRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
E ++S + V W N +++K DD+ + V G L I SD G + G +
Sbjct: 2465 ECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK--GTKQRLVINRTHASDEGPYKLIVGRV 2522
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
L++++ IK + L+++ E E EL+ + + W + + +KY +
Sbjct: 2523 ETNCNLSVEK--IKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKI 2580
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
GK +L + + D G+YT A E ++ +TV + ++D A
Sbjct: 2581 EAHGKIYKLTVLNMMKDDEGKYTFYA------GENMTSGKLTVAG--GAISKPLTDQTVA 2632
Query: 527 TGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF 585
A C V N + +G WL+DGK + ++ G +LI + + G+YT+
Sbjct: 2633 ESQEAVFECEVANPDS-KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTY 2691
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+ +++ A + + +V +TV A V + V W K+G
Sbjct: 2692 KVATSKTSAKLKV-------EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNG 2744
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQ 705
+ + E+ ++ L I NC D + +L A+A LH+ + K P+
Sbjct: 2745 VVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRL--GRLGASARLHVETVKIIKKPK 2802
Score = 98.2 bits (243), Expect = 5e-20
Identities = 145/714 (20%), Positives = 274/714 (38%), Gaps = 108/714 (15%)
Query: 3 TIHSRQMLQEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPA 62
T+ + L VS EF TT V T K EE +S +V + +T P
Sbjct: 1023 TVSTSCYLAVQVSEEFEKETTAV-----TEKFTTEEKRFVESRDVVMTDTSLTEEQAGPG 1077
Query: 63 GDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA--KIFYDSIN 120
+ P F+ KP EG VF +V GN KPH+ WK+ SG+P+ K+ Y+
Sbjct: 1078 EPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK-SGVPLTTGYRYKVSYNKQT 1136
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK 180
E L + +DD+ Y + N H + + SLL E+ D++ ++K + +
Sbjct: 1137 GECKLVISMTFADDAGEYTIVVRNKHGETSASASLL-----EEADYELLMKSQQEMLYQT 1191
Query: 181 KQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPL 240
+ E ++ E ++EK EY ++ ++KK+ + + + +
Sbjct: 1192 QVTAFVQEPKVGETAPGFVYSEYEK---EYE--------KEQALIRKKMAKDTVVVRTYV 1240
Query: 241 EDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNV 300
ED+E + + ++ +K I+Y + K ++++
Sbjct: 1241 EDQEFHISS---------FEERLIK----------EIEYRIIKTTLEEL----------- 1270
Query: 301 NMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKE-PNFV 359
+ + G ++V A + D +K ++ E F ++S P
Sbjct: 1271 -LEEDGEEKMAVDISESEAVESGFDS------RIKNYRILEGMGVTFHCKMSGYPLPKIA 1323
Query: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQLTID 415
W +GK +K ++Y++ +DG +L+I D G ++A A GN + +L ++
Sbjct: 1324 WYKDGKRIKHGERYQMDFLQDGRA-SLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382
Query: 416 -RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAE 474
P+ + + + R R+ ++ + + + M + S
Sbjct: 1383 PAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMS--------- 1433
Query: 475 LIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH--AATGSPAE 532
A++S G +++ D ++ ERL + V G A
Sbjct: 1434 ----PARMSPGRR-----LEETDESQL---------ERLYKPVFVLKPVSFKCLEGQTAR 1475
Query: 533 LCV-VLNDEKVEGVWLKDGKEIT-DLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
+ V+ E W DG++I D ++K+ LI P G++T A+
Sbjct: 1476 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1535
Query: 591 ESEASVFI-----ADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+S+ + A + P +E L + +K G +KV G P P + W K+
Sbjct: 1536 AGRSSISVILTVEAVEHQVKPMFVEKLKN--VNIKEGSRLEMKVRATGNPNPDIVWLKNS 1593
Query: 646 MEVTEEE--RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
+ + ++ +E + +A L I + V +DS N G T ++V
Sbjct: 1594 DIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647
Score = 92.8 bits (229), Expect = 2e-18
Identities = 110/495 (22%), Positives = 193/495 (38%), Gaps = 34/495 (6%)
Query: 232 EAIRILKPLEDKETKV-DTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
+ I + L+D K DT F+C E +P VK+ W K + + KY +
Sbjct: 2172 QLITFTQELQDVVAKEKDTMATFEC--ETSEPFVKVKWYKDGMEV---HEGDKYRMHSDR 2226
Query: 291 TKYMLVISNVNMNDAGIYS-LSVGDKRM--SAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
+ L I ++ +DA YS + V D+ + +A+L V ++F+ E++ ++V E +
Sbjct: 2227 KVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGEL 2286
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E +S + W N ELK + KY IT S G L +KD D GE+S
Sbjct: 2287 ECIVSPENIEGKWYHNDVELKSNGKYTIT-SRRG-RQNLTVKDVTKEDQGEYSFVIDGKK 2344
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
+L + PI + L + +V E LE +++ + V W KDGQ + + +
Sbjct: 2345 TTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIV 2404
Query: 468 HEGKRAELIIEDAQLSDGGEYT----VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
+ + L+IED D G Y+ + + YS ++T + DV
Sbjct: 2405 IDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVIT----------PLKDV 2454
Query: 524 HAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGK 582
+ G+ A L C V + W + ++I +Q + +G +L+ EG
Sbjct: 2455 NVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGP 2514
Query: 583 YTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWY 642
Y E+ ++ + ++ L T +++ G V W
Sbjct: 2515 YKLIVGRVETNCNLSVE-----KIKIIRGLRDLTCTETQNVVFEVELSHSG---IDVLWN 2566
Query: 643 KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPK 702
E+ + +E LT+ N +++D G + S T+ + +P
Sbjct: 2567 FKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAISKPL 2626
Query: 703 PPQGRVEFLELSGSC 717
Q E E C
Sbjct: 2627 TDQTVAESQEAVFEC 2641
Score = 73.9 bits (180), Expect = 9e-13
Identities = 141/679 (20%), Positives = 253/679 (37%), Gaps = 92/679 (13%)
Query: 54 VTRSSNIPAGDSVP----EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIK 109
VT ++ +PA +P V + VT EG+ + G P ++W RE I+
Sbjct: 926 VTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYRED-YQIE 984
Query: 110 ESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKM 169
S + L + ++DS + C A N+ A + T L + E+ +
Sbjct: 985 SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNE-AGTVSTSCYLAVQVSEEFE---- 1039
Query: 170 LKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKV 229
K+ EK E V +D V + T+ ++
Sbjct: 1040 -----------KETTAVTEKFTTEEKRFVESRDV--VMTDTSLTE--------EQAGPGE 1078
Query: 230 EVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQM 289
I KP+ K + +VVF C + +P + W K PL Y KQ
Sbjct: 1079 PAAPYFITKPVVQKLVE-GGSVVFGCQVG-GNPKPHVYWKKSGVPLTTGYRYKVSYNKQT 1136
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKR--MSAELTVLDEP---LKFLGEMKPVKVTERQT 344
G + LVIS +DAG Y++ V +K SA ++L+E L + + + T+
Sbjct: 1137 G-ECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTA 1195
Query: 345 AVFEIRLSKKEPNFVWKFNGKELKR---------------------DDKYEITVSEDGLT 383
V E ++ + P FV+ KE ++ D ++ I+ E+ L
Sbjct: 1196 FVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLI 1255
Query: 384 HTLKIKDARLSDSGEFSAEAGNLVQKAQLT-IDRIPIKFVSNLKNVRVKERSRACLECEL 442
++ + + + E E G ++ + + F S +KN R+ E C++
Sbjct: 1256 KEIEYRIIKTTLE-ELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKM 1314
Query: 443 TSKDVT-LRWKKDGQLLMHGTKYSMNH-EGKRAELIIEDAQLSDGGEYTVVAMQDGDPTE 500
+ + + W KDG+ + HG +Y M+ + RA L I D G YT A +
Sbjct: 1315 SGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFA------SN 1368
Query: 501 YYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQ 560
AI + + + + + T P L+ V I P
Sbjct: 1369 IKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSV------SRSPIRMSPARM 1422
Query: 561 IVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVK 620
+ + ++ M P + T ++ VF+ P + LE
Sbjct: 1423 SPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKP--VSFKCLE---------- 1470
Query: 621 VGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVREDSGLI 678
G TA + G+P+P+ W+ DG ++ + +V ++ Q+L+ + DSG
Sbjct: 1471 -GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVP-ATPSDSGEW 1528
Query: 679 LLKLKNDHGSATATLHLSV 697
+ +N G ++ ++ L+V
Sbjct: 1529 TVVAQNRAGRSSISVILTV 1547
Score = 68.2 bits (165), Expect = 5e-11
Identities = 46/164 (28%), Positives = 76/164 (46%), Gaps = 7/164 (4%)
Query: 546 WLKDGKEITD--LPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA---KGTESEASVFIAD 600
W +DG+ I+ LPG+QI KL P++ + G+Y+ +A G + + +
Sbjct: 39 WFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
T P+ ++ L ++TV+ G ++V G P P V +Y+DG E+ + +
Sbjct: 99 AETAPPNFVQRL--QSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEG 156
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
D L I+ EDSG + N G AT+T L V + P
Sbjct: 157 DLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Score = 62.8 bits (151), Expect = 2e-09
Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 1/115 (0%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P V+ LK TV+ G+ T+ C G P PTVT Y+ D I ++ F SG+ L+I
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD-KSVVASITESLQKKSKHLM 1326
+DSG ++ NE G +SC L V ++ + ++TE + K +
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFV 1057
Score = 56.2 bits (134), Expect = 2e-07
Identities = 27/89 (30%), Positives = 50/89 (56%), Gaps = 2/89 (2%)
Query: 71 EKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPL 130
E P+ EGD + + G +P ++W ++G+ +K++ K ++ +N H L ++ +
Sbjct: 4163 EMPKHARCREGDSIILECLISGEPQPVVTWF-QNGVLLKQNQKFQFEEVNCSHQLYIKDV 4221
Query: 131 TSDDSDNYKCIASNDHADAIYTVSLLVTE 159
S DS YKC+A N ++ A+ +VS L E
Sbjct: 4222 NSQDSGKYKCVAEN-NSGAVESVSDLTVE 4249
Score = 55.8 bits (133), Expect = 3e-07
Identities = 99/494 (20%), Positives = 176/494 (35%), Gaps = 85/494 (17%)
Query: 316 RMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYE 374
R+ A + + P + +K V V E ++ E +S P W +++ ++
Sbjct: 931 RVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQ 990
Query: 375 ITVSEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTID----------RIPIK 420
IT + G+ L I++A DSG F+ EAG + L + + K
Sbjct: 991 ITF-QSGIAR-LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1048
Query: 421 FVSNLKNVRVKERSRACLECELTSKDVT-------------------------------- 448
F + K V+ R + LT +
Sbjct: 1049 FTTEEKRF-VESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1107
Query: 449 -----LRWKKDGQLLMHGTKYSMNHEGKRAE--LIIEDAQLSDGGEYTVVAMQDGDPTEY 501
+ WKK G L G +Y +++ + E L+I D GEYT+V T
Sbjct: 1108 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS- 1166
Query: 502 YSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQI 561
++A + E + ++ T A + E G + ++ + I
Sbjct: 1167 -ASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALI 1225
Query: 562 VKQGAVHKLIFPSMGPEHE-----------GKYTFRAKGT----------ESEASVFIAD 600
K+ A ++ + + E + +R T E + +V I++
Sbjct: 1226 RKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISE 1285
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
++ + + I +G T H K+ G PLPK+ WYKDG + ER M+ +
Sbjct: 1286 SEAVESGFDSRIKNYRILEGMGVTFHCKMS--GYPLPKIAWYKDGKRIKHGERYQMDFLQ 1343
Query: 661 D-QALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVH 719
D +A L I + ED G+ N G+A + L V P P G ++
Sbjct: 1344 DGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYV--EPAAPLGAPTYIPTLEPVSR 1401
Query: 720 MKWKAPKDNGGRPV 733
++ +P+ P+
Sbjct: 1402 IRSLSPRSVSRSPI 1415
Score = 55.5 bits (132), Expect = 3e-07
Identities = 60/288 (20%), Positives = 106/288 (36%), Gaps = 19/288 (6%)
Query: 1028 FSGSPPPDVIWQKDGVPTKGRET--ITKSKNHSQFLINSTKRSDSGVYRILLQNEFG--- 1082
F G P P V W + +P + I +N+S ++S + G +L N++G
Sbjct: 3967 FQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITCVLFNQYGTVK 4026
Query: 1083 -------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
+A+ V+ P L EE+ P + ++G+ + ++K
Sbjct: 4027 TTSMLKVKAKQKHDVKAHKVPVFHDYLDEEEELALVFDQAKGAHPSMSQEGQTNLHLLKT 4086
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ 1195
+ F + VT P + + E+ +E L+ + + +DQ+
Sbjct: 4087 NPPVPPSGDTELLSFPVEIQVTAATPIPE---QDKESKEVFQTEELEPK---AMPQDQVT 4140
Query: 1196 DLSAKLKPYEKKDWRHAPRFVTPLKPHTVLR-GQDCTMTCAFLGNPRPTVTLYKGDVNIT 1254
+ P+ + + H R G + C G P+P VT ++ V +
Sbjct: 4141 QSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLK 4200
Query: 1255 ANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
N KF + + L I +DSG Y + EN G S LTV
Sbjct: 4201 QNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTV 4248
Score = 54.7 bits (130), Expect = 6e-07
Identities = 70/335 (20%), Positives = 125/335 (37%), Gaps = 65/335 (19%)
Query: 237 LKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGT----- 291
+ P E++ + V +ME + + + ++ L + DVK+
Sbjct: 5272 IMPQEERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIV 5331
Query: 292 ---------KYMLVISNV---NMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKV 339
K M+V +V N D + S DK + +L V + P +F+ + K+
Sbjct: 5332 TVPEFTPDHKSMIVSLDVLPFNFVDPNMDSREGEDKELKIDLEVFEMPPRFIMPICDFKI 5391
Query: 340 TERQTAVFEIR-LSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGE 398
E AVF+ + P W + D + +SE+ +HTLKI++ LSDS
Sbjct: 5392 PENSDAVFKCSVIGIPTPEVKW-YKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSAT 5450
Query: 399 FSAEAGNLV---------------------QKAQLTIDRI-------------------- 417
+ A N V +K+++T+ +
Sbjct: 5451 YRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVV 5510
Query: 418 --PIKFVSNLKNVRVKERSRACLECELT-SKDVTLRWKKDGQLLMHGTKYSMNHEGKR-A 473
P +F+ + + + A +C + S T+ W KDG+ L+ G ++++ G
Sbjct: 5511 EGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGK-LVQGRRFTVEESGTGFH 5569
Query: 474 ELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVT 508
L I SD GEY VA E ++ +T
Sbjct: 5570 NLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604
Score = 53.1 bits (126), Expect = 2e-06
Identities = 29/109 (26%), Positives = 48/109 (44%)
Query: 1204 YEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNS 1263
+ K+ R P F+ ++ V G C C F G P+P VT Y D+ I N F +S
Sbjct: 3935 FRKRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHS 3994
Query: 1264 TSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVA 1312
L + + ++ G + ++ N+ G +++ L V K V A
Sbjct: 3995 LENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKA 4043
Score = 52.4 bits (124), Expect = 3e-06
Identities = 70/313 (22%), Positives = 120/313 (38%), Gaps = 39/313 (12%)
Query: 999 PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-TKG---RETITKS 1054
PAAP F ++ + +V G ++ G+P P V W+K GVP T G + + K
Sbjct: 1079 PAAPYF-ITKPVVQKLV--EGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQ 1135
Query: 1055 KNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+ +I+ T D+G Y I+++N+ GE + L EE + +
Sbjct: 1136 TGECKLVISMTFADDAGEYTIVVRNKHGET--------------SASASLLEEADYELLM 1181
Query: 1115 TWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKY-YFRVVARN 1173
Q A ++ + TA + +E + +Y L +K VV R
Sbjct: 1182 KSQQEMLYQTQVTA-FVQEPKVGETAPGFVYSE--YEKEYEKEQALIRKKMAKDTVVVRT 1238
Query: 1174 EIGDSE-PLDSRDTWLINKDQIQDLSAKLKPYEKKDWRH------------APRFVTPLK 1220
+ D E + S + LI + + + + L+ ++D F + +K
Sbjct: 1239 YVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIK 1298
Query: 1221 PHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN-STSGVCTLVIPTCTLKD 1279
+ +L G T C G P P + YK I ++ + G +L IP +D
Sbjct: 1299 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358
Query: 1280 SGDYSVLVENELG 1292
G Y+ N G
Sbjct: 1359 EGIYTAFASNIKG 1371
Score = 52.4 bits (124), Expect = 3e-06
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFW--YNSTSGVCT 1269
AP F+T ++ G C GNP+P V K V +T ++ YN +G C
Sbjct: 1081 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1140
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
LVI D+G+Y+++V N+ G+ +S +L
Sbjct: 1141 LVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 50.8 bits (120), Expect = 8e-06
Identities = 46/197 (23%), Positives = 84/197 (42%), Gaps = 8/197 (4%)
Query: 330 FLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKI 388
F ++ V V E TA FE +S P W +G+ + + +S L I
Sbjct: 8 FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTI 67
Query: 389 KDARLSDSGEFSAEA----GNLVQKAQLTI--DRIPIKFVSNLKNVRVKERSRACLECEL 442
++SG +S +A G A+L + + P FV L+++ V++ S+ L+ +
Sbjct: 68 PAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRV 127
Query: 443 TSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEY 501
T +++ +DG + + ++ EG L+I +A D G Y+V A
Sbjct: 128 TGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATS 187
Query: 502 YSTAIVTVEERLATVKS 518
+ +V EE + K+
Sbjct: 188 TAELLVQGEEEVPAKKT 204
Score = 50.8 bits (120), Expect = 8e-06
Identities = 79/329 (24%), Positives = 127/329 (38%), Gaps = 42/329 (12%)
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSK--NHSQFLINSTKRSDSGVY 1073
V T L G P P V W ++ + E I + N I++ ++ + G Y
Sbjct: 5194 VYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEY 5253
Query: 1074 RILLQNEFGEARYDIHV-------RVADFPRPPTNLRLFE-EVPNTVTLTWNHSPDVQED 1125
N GEA+ +V RV P P T+ + E ++ +T T + +P QE
Sbjct: 5254 MCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHT---TSSRTPSPQE- 5309
Query: 1126 GEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEP-LDSR 1184
I+++ + S ++V TV P K + +P +DSR
Sbjct: 5310 -----IVLEVELSEKDVKEFEKQV--KIVTVPEFTPDHKSMIVSLDVLPFNFVDPNMDSR 5362
Query: 1185 DTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTV 1244
+ + ++L L+ +E PRF+ P+ + D C+ +G P P V
Sbjct: 5363 E------GEDKELKIDLEVFEMP-----PRFIMPICDFKIPENSDAVFKCSVIGIPTPEV 5411
Query: 1245 TLYKGDVNITA-NSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVY 1303
YK + I N K+ + G TL I L DS Y N +G+ LT+
Sbjct: 5412 KWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMG 5471
Query: 1304 D--------KDDKSVVASITESLQKKSKH 1324
D K K ++S+ E L KS +
Sbjct: 5472 DSEIFAVIAKKSKVTLSSLMEELVLKSNY 5500
Score = 50.1 bits (118), Expect = 1e-05
Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVRE 673
++ V G TA + G P+P+V+W++DG ++ V + + +A LTI +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 674 DSGLILLKLKNDHGSATATLHLSVLDRPKPP 704
+SG LK N G AT+T L V PP
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 48.9 bits (115), Expect = 3e-05
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P FV L+ TV +G + G P P V Y+ I ++ F + + +L+I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD------KSVV--ASITESLQKK 1321
+DSG YSV N +G+ S+ L V +++ K++V A I+ES Q +
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTR 220
Score = 47.4 bits (111), Expect = 9e-05
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 5/109 (4%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSK-FWYNSTSGVCTL 1270
AP+ ++ TV +G D +G P P YK V I + + +WY VC L
Sbjct: 2077 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCEL 2136
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQ 1319
VI T +DS V N G+ S L V K + + T+ LQ
Sbjct: 2137 VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ----LITFTQELQ 2181
Score = 47.4 bits (111), Expect = 9e-05
Identities = 36/107 (33%), Positives = 50/107 (46%), Gaps = 6/107 (5%)
Query: 52 SLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISW-KRESGIPIKE 110
S VT N P P+ +++ QPVT G A F A + G +P ISW K E +
Sbjct: 3227 SSVTLYVNAP---EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGF 3283
Query: 111 SAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV 157
K +D +E+ L L +D+ Y C A ND+ A + SL V
Sbjct: 3284 KCKFLHD--GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3328
Score = 47.4 bits (111), Expect = 9e-05
Identities = 98/484 (20%), Positives = 173/484 (35%), Gaps = 89/484 (18%)
Query: 237 LKPLEDKETKVDTTVVFDCIME-LKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYML 295
++PL ++ +TT+ F +E L P VK W + L + ++++G L
Sbjct: 5186 IEPLTKRKVYENTTLGFIVEVEGLPVPGVK--WYRNKSLLEPDERI---KMERVGNVCSL 5240
Query: 296 VISNVNMNDAGIYSLS----VGDKRMSAELTVLDEPLKFLGEMKPV-------------- 337
ISN+ + G Y +G+ + A + ++ + + + PV
Sbjct: 5241 EISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHTT 5300
Query: 338 --KVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSD 395
+ Q V E+ LS+K+ V +F K++K E T + +L + D
Sbjct: 5301 SSRTPSPQEIVLEVELSEKD---VKEFE-KQVKIVTVPEFTPDHKSMIVSLDVLPFNFVD 5356
Query: 396 SGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVT-LRWKKD 454
S E + K L + +P +F+ + + ++ E S A +C + ++W K+
Sbjct: 5357 PNMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKE 5416
Query: 455 GQLLM-HGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERL 513
+ KY ++ E L I + LS D Y A+ V E +
Sbjct: 5417 YMCIEPDNIKYVISEEKGSHTLKIRNVCLS-------------DSATYRCRAVNCVGEAI 5463
Query: 514 ATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFP 573
+ + D ++ V K K + + +L+
Sbjct: 5464 CRG-----------------FLTMGDSEIFAVIAKKSK---------VTLSSLMEELVLK 5497
Query: 574 SMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRG 633
S YT + E V + PP + + A +G A+ + RG
Sbjct: 5498 S-------NYT----DSFFEFQV-VEGPPRFIKGISDCYAP------IGTAAYFQCLVRG 5539
Query: 634 KPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
P P V WYKDG V E G L I++ V+ D G N G A +
Sbjct: 5540 SPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFA 5599
Query: 694 HLSV 697
L++
Sbjct: 5600 ALTL 5603
Score = 46.6 bits (109), Expect = 2e-04
Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Query: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660
P PS L+ + + V G + + F+G P P VTWY + M + + + E
Sbjct: 3939 PQRCPPSFLQEIESQE--VYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLE 3996
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPK 702
+ ++LT+S+ ++ G I L N +G+ T L V + K
Sbjct: 3997 NYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQK 4038
Score = 45.1 bits (105), Expect = 5e-04
Identities = 76/336 (22%), Positives = 122/336 (36%), Gaps = 56/336 (16%)
Query: 3 TIHSRQMLQEHVSMEFSSSTTHVQTFSQTTKIVG-EEVVRRKSSSIVEF----FSLVTRS 57
T SR + + +E S V+ F + KIV E S IV F+ V +
Sbjct: 5299 TTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPEFTPDHKSMIVSLDVLPFNFVDPN 5358
Query: 58 SNIPAGDSV------------PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESG 105
+ G+ P F+ PE AVF+ V G P + W +E
Sbjct: 5359 MDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYM 5418
Query: 106 IPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMD 165
++ K H LK+ + DS Y+C A N +AI L T G ++
Sbjct: 5419 CIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFL--TMGDSEI- 5475
Query: 166 FKKMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEM 225
F + KK KV M E++ K D F +F
Sbjct: 5476 FAVIAKK----------SKVTLSSLMEELVLKSNYTD--------SFFEF---------- 5507
Query: 226 KKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYD 285
+V R +K + D + T F C++ P + W K + ++ + ++
Sbjct: 5508 --QVVEGPPRFIKGISDCYAPIGTAAYFQCLVR-GSPRPTVYWYKDGKLVQGR----RFT 5560
Query: 286 VKQMGTKY-MLVISNVNMNDAGIYSLSVGDKRMSAE 320
V++ GT + L I+++ +D G Y +K AE
Sbjct: 5561 VEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAE 5596
Score = 44.3 bits (103), Expect = 8e-04
Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 8/112 (7%)
Query: 323 VLDEPLKFLGEM-KPVKVTERQTAVFEIRLS-KKEPNFVWKFNGKELKRDDKYEITVSED 380
+ +EP K L EM K + E + + E +S + +P W NG LK++ K++ E
Sbjct: 4153 ITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQF--EEV 4210
Query: 381 GLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQLTIDRIPIKFVSNLKNV 428
+H L IKD DSG++ A G + + LT++ + + S +N+
Sbjct: 4211 NCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPVTYRENSQFENI 4262
Score = 43.1 bits (100), Expect = 0.002
Identities = 46/213 (21%), Positives = 81/213 (38%), Gaps = 6/213 (2%)
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMS---DVHAATGSPAELCVVLNDEKVEGV 545
+V + G +AI T+++ L+ S V A T P+E V +
Sbjct: 822 SVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQF 881
Query: 546 WLKDGKEI-TDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
D + G+++ K+ V E + AK TE+ + P
Sbjct: 882 PFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVT 941
Query: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL 664
P+++ L +TV G + ++ G P P VTWY++ ++ + A
Sbjct: 942 PPTLVSGLKN--VTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIAR 999
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
L I EDSG N+ G+ + + +L+V
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 43.1 bits (100), Expect = 0.002
Identities = 73/336 (21%), Positives = 119/336 (35%), Gaps = 70/336 (20%)
Query: 1030 GSPPPDVIWQKDG---VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
G P P+ W DG V + + K +I SDSG + ++ QN G +
Sbjct: 1482 GRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSI 1541
Query: 1087 DI--HVRVADFPRPP--------TNLRLFEEVPNTVTLTWNHSPDVQ------------- 1123
+ V + P N++ + V T N +PD+
Sbjct: 1542 SVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKY 1601
Query: 1124 -------EDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTG-----------------L 1159
GEA I + + WYTA + + T +
Sbjct: 1602 PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLI 1661
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSR---DTWLINKDQIQDLSAKLKPYEKKDWRHAPRFV 1216
+P Y + +A E+ EPL R + W + + D + KP+ KK +
Sbjct: 1662 IPRGTYRAKEIAAPEL---EPLHLRYGQEQW--EEGDLYDKEKQQKPFFKKK-------L 1709
Query: 1217 TPLKPHTVLRGQ-DCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
T L+ +C +T +G+P V + A ++ + G C+L
Sbjct: 1710 TSLRLKRFGPAHFECRLTP--IGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVA 1767
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVV 1311
+DSG + N+ G D +S TL V KD+KS+V
Sbjct: 1768 YSRDSGIITCRATNKYGTDHTSATLIV--KDEKSLV 1801
Score = 42.7 bits (99), Expect = 0.002
Identities = 57/273 (20%), Positives = 106/273 (38%), Gaps = 30/273 (10%)
Query: 1032 PPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P V W KD + R I K K + LI ST+ SD+G Y ++ A+ +
Sbjct: 3084 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3143
Query: 1090 VRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERV 1149
R +++ E+ V N ++D +AH+ +D + ER
Sbjct: 3144 GRDVRIRSIKKEVQVIEKQRAVVEFEVN-----EDDVDAHWY---KDGIEIN-FQVQER- 3193
Query: 1150 FSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
+KY V R + R I ++ D+ + + ++ + E
Sbjct: 3194 --HKYVVE----------RRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPE---- 3237
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
P+ + L+P TV G+ G P+P ++ YK + ++ K + T
Sbjct: 3238 --PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT 3295
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L++ +D+ Y+ +N+ G +S +L+V
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3328
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Query: 596 VFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVS 655
VF++D P +L+ + HA + G + ++ G+P P VTW+++G+ + + ++
Sbjct: 4148 VFLSDITNEPPKMLQEMPKHA-RCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQ 4206
Query: 656 MERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
E L I + +DSG +N+ G+ + L+V
Sbjct: 4207 FEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTV 4248
Score = 42.0 bits (97), Expect = 0.004
Identities = 28/69 (40%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Query: 1019 GTALCIHAAFSGSPPPDVIWQKDGVPTKGRE-TITKSKN--HSQFLINSTKRSDSGVYRI 1075
GTA GSP P V W KDG +GR T+ +S H+ F I S +SD G YR
Sbjct: 5528 GTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLF-ITSLVKSDEGEYRC 5586
Query: 1076 LLQNEFGEA 1084
+ N+ G A
Sbjct: 5587 VATNKSGMA 5595
Score = 40.4 bits (93), Expect = 0.011
Identities = 39/176 (22%), Positives = 72/176 (40%), Gaps = 10/176 (5%)
Query: 4 IHSRQMLQEHVSME----FSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSN 59
+H R +++ + ME FS + E + KS + + S ++ +S+
Sbjct: 3440 LHER--IEQEIEMEMKELFSEGESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSS 3497
Query: 60 IPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISW---KRESGIPIKESAKIFY 116
P P F +K EG+ VF R+ P ++W R ++ K
Sbjct: 3498 WPEYFK-PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAES 3556
Query: 117 DSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKK 172
D + L+++ + DS +Y+ +A N A T SLLV + + + + LK+
Sbjct: 3557 DLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKR 3612
Score = 40.4 bits (93), Expect = 0.011
Identities = 23/101 (22%), Positives = 45/101 (44%), Gaps = 2/101 (1%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P F+++ + EGD F QG +P ++W + +PI + S+ +L
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTW-YNNDMPIPRNQNFIIHSLENYSILT 4002
Query: 127 LEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFK 167
L + + + C+ N + + T S+L + ++K D K
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYG-TVKTTSMLKVKAKQKHDVK 4042
Score = 40.4 bits (93), Expect = 0.011
Identities = 70/308 (22%), Positives = 114/308 (37%), Gaps = 37/308 (12%)
Query: 415 DRIPIKFVSNLKNVRVKERSRACLECELTSKDVT-LRWKKDGQLLMHGTKYSMNHEGKRA 473
+ +P F+ L +V E + E+ V ++W ++ LL + M G
Sbjct: 5179 NEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVC 5238
Query: 474 ELIIEDAQLSDGGEYTVVAMQ-DGDPTEYYSTAIVTVEERLATVKSGMSDVH-------- 524
L I + Q +GGEY A+ G+ + + I+ EER+ + ++ H
Sbjct: 5239 SLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEH 5298
Query: 525 ---AATGSPAELCVVLN-DEKVEGVWLKDGKEIT------DLPGMQIVKQGAVHKLIFPS 574
+ T SP E+ + + EK + K K +T D M + + P+
Sbjct: 5299 TTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPEFTPDHKSMIVSLDVLPFNFVDPN 5358
Query: 575 MGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGK 634
M EG+ K + + VF P I P + A K G
Sbjct: 5359 M-DSREGE----DKELKIDLEVFEMPPRFIMPIC-------DFKIPENSDAVFKCSVIGI 5406
Query: 635 PLPKVTWYKDGMEVTEEE---RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATA 691
P P+V WYK+ M + + +S E+G L I N DS + N G A
Sbjct: 5407 PTPEVKWYKEYMCIEPDNIKYVISEEKGSH--TLKIRNVCLSDSATYRCRAVNCVGEAIC 5464
Query: 692 TLHLSVLD 699
L++ D
Sbjct: 5465 RGFLTMGD 5472
Score = 39.7 bits (91), Expect = 0.019
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS--KFWYNSTSGVCT 1269
AP F PL+ VL G T G P P V+ ++ I+ ++ + + G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L IP T +SG YS+ N G+ S+ L V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 39.7 bits (91), Expect = 0.019
Identities = 62/301 (20%), Positives = 101/301 (33%), Gaps = 54/301 (17%)
Query: 1008 ARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKS---KNHSQFLINS 1064
+R+K++ ++ G + H SG P P + W KDG K E + I
Sbjct: 1295 SRIKNYRILE-GMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPV 1353
Query: 1065 TKRSDSGVYRILLQNEFGEARYD--IHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDV 1122
D G+Y N G A ++V A PT + E V +L+
Sbjct: 1354 VLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLS------- 1406
Query: 1123 QEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
R S + + R+ + + + P R + L+
Sbjct: 1407 -----------PRSVSRSPIRMSPARMSPARMSPARMSPAR-----------MSPGRRLE 1444
Query: 1183 SRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP 1242
D + Q++ L + P FV L GQ +G P P
Sbjct: 1445 ETD-----ESQLERL-------------YKPVFVLKPVSFKCLEGQTARFDLKVVGRPMP 1486
Query: 1243 -TVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLT 1301
T + G + + G +L+I T DSG+++V+ +N G+ S LT
Sbjct: 1487 ETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILT 1546
Query: 1302 V 1302
V
Sbjct: 1547 V 1547
Score = 39.3 bits (90), Expect = 0.025
Identities = 30/123 (24%), Positives = 49/123 (39%), Gaps = 9/123 (7%)
Query: 1010 LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNH--SQFLINSTKR 1067
+ H R G ++ + SG P P V W ++GV K + + + Q I
Sbjct: 4164 MPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNS 4223
Query: 1068 SDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPD--VQED 1125
DSG Y+ + +N G V+D P R + N + +S D +Q+
Sbjct: 4224 QDSGKYKCVAENNSGAVE-----SVSDLTVEPVTYRENSQFENIGEIYGKYSRDQQLQDQ 4278
Query: 1126 GEA 1128
GE+
Sbjct: 4279 GES 4281
Score = 38.5 bits (88), Expect = 0.043
Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 1/106 (0%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV-L 125
P F + Q V EG A F A + G P +SW R+ + + S + L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171
+ +T +S Y A+N A T LLV +F + L+
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQ 111
Score = 38.5 bits (88), Expect = 0.043
Identities = 25/90 (27%), Positives = 35/90 (38%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
PRF+ + G C G+PRPTV YK + S +G L I
Sbjct: 5514 PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFI 5573
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
+ D G+Y + N+ G S LT+
Sbjct: 5574 TSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 38.1 bits (87), Expect = 0.056
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P F++ AP G A F+ V+G+ +P + W ++ G ++ +S H L
Sbjct: 5514 PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKD-GKLVQGRRFTVEESGTGFHNLF 5572
Query: 127 LEPLTSDDSDNYKCIASNDHADAIYTVSLLVT 158
+ L D Y+C+A+N A +L +T
Sbjct: 5573 ITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604
Score = 37.4 bits (85), Expect = 0.096
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 1/98 (1%)
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
+ P V +P VL G+ C G P+P V Y I + +F G+
Sbjct: 1838 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHY 1896
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
L I C D+G+ V EN G L + ++D
Sbjct: 1897 LDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1934
Score = 36.6 bits (83), Expect = 0.16
Identities = 41/147 (27%), Positives = 59/147 (40%), Gaps = 22/147 (14%)
Query: 1176 GDSE--PLDSRDTWLINKDQIQDLSAKLKPYEKK-----DWRH--APRFVTPLKPHTVLR 1226
G+SE D+RD + ++D I S K Y + W P F L VL
Sbjct: 3459 GESEHSERDTRDAFSDSED-IDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLE 3517
Query: 1227 GQDCTMTCAFLGNPRPTVTLYKGDVN--------ITANSKFWYNSTSGVCTLVIPTCTLK 1278
G+ TC + P P +T + + I A S ++S+S L I +
Sbjct: 3518 GEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSS----LEIKRVQDR 3573
Query: 1279 DSGDYSVLVENELGKDRSSCTLTVYDK 1305
DSG Y +L N G S+ +L V K
Sbjct: 3574 DSGSYRLLAINSEGSAESTASLLVIQK 3600
Score = 36.6 bits (83), Expect = 0.16
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Query: 426 KNVRVKERSRACLECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSD 484
K+ R +E LEC ++ + + W ++G LL K+ +L I+D D
Sbjct: 4166 KHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQD 4225
Query: 485 GGEYTVVAMQDGDPTEYYSTAIVTVE 510
G+Y VA + E S + +TVE
Sbjct: 4226 SGKYKCVAENNSGAVE--SVSDLTVE 4249
Score = 36.2 bits (82), Expect = 0.21
Identities = 23/106 (21%), Positives = 40/106 (37%)
Query: 1205 EKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNST 1264
E KD P F+ PL V G P P V Y+ + + +
Sbjct: 5175 EPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERV 5234
Query: 1265 SGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSV 1310
VC+L I + G+Y N +G+ +S + + ++++ V
Sbjct: 5235 GNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVV 5280
Score = 35.4 bits (80), Expect = 0.37
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDG----VPTKGRETITKSKNHSQFLINSTKRSD 1069
+VV G+ A SG P P+V W +DG T I+ S ++ I + +++
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKAN 74
Query: 1070 SGVYRILLQNEFGEARYDIHVRVADFPRPP 1099
SG Y + N G+A + V PP
Sbjct: 75 SGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 34.3 bits (77), Expect = 0.82
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDG---VPTK-GRETITKSKNHSQFLINSTKRSDSG 1071
++ G+ L + +G+P PD++W K+ VP K + I +K + I+ST DS
Sbjct: 1567 IKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSA 1626
Query: 1072 VYRILLQNEFGE--ARYDIHVRVADFPRPPTNLRL 1104
Y N+ G R ++V V +F P +L
Sbjct: 1627 WYTATAINKAGRDTTRCKVNVEV-EFAEPEPERKL 1660
Score = 33.5 bits (75), Expect = 1.4
Identities = 36/161 (22%), Positives = 65/161 (40%), Gaps = 12/161 (7%)
Query: 973 FRIRAVNEAGVG-EPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGS 1031
+ ++A N +G EL PP + RL+S M VR G+ + + +G
Sbjct: 78 YSLKATNGSGQATSTAELLVKAETAPP------NFVQRLQS-MTVRQGSQVRLQVRVTGI 130
Query: 1032 PPPDVIWQKDGVPTKGR--ETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIH 1089
P P V + +DG + I++ + LI DSG Y + N G A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAE 190
Query: 1090 VRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHY 1130
+ V P + + + +T ++ + +++ EAH+
Sbjct: 191 LLVQGEEEVPA--KKTKTIVSTAQISESRQTRIEKKIEAHF 229
Score = 32.0 bits (71), Expect = 4.0
Identities = 15/54 (27%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 1247 YKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTL 1300
Y DV + +N K+ S G L + T +D G+YS +++ + +++C L
Sbjct: 2300 YHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK----KTTCKL 2349
Score = 30.8 bits (68), Expect = 9.0
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
Query: 277 IQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLDEPLKFLG 332
IQ SL + + Q G Y L+I+ D+G YS+ SVG +AEL V E
Sbjct: 144 IQSSLD-FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAK 202
Query: 333 EMKPVKVTERQTAVFEIRLSKK 354
+ K + T + + + R+ KK
Sbjct: 203 KTKTIVSTAQISESRQTRIEKK 224
>gi|140560917 myomesin 1 isoform b [Homo sapiens]
Length = 1589
Score = 190 bits (483), Expect = 7e-48
Identities = 154/597 (25%), Positives = 258/597 (43%), Gaps = 54/597 (9%)
Query: 637 PKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLS 696
P++ WY++G+ ++ + V ++A LT S+ +ED GL ++++ + ++
Sbjct: 439 PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
Query: 697 VLDRPKPPQGR------VEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK 750
V D +G V+ LE + + + WK P +GG P+ + +++ VG SW +
Sbjct: 499 VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
Query: 751 IGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQ 809
+ K F + EG++Y FR+ AVN G+ P E V A +P E S+P
Sbjct: 559 CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
Query: 810 ---------------------------VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRK 842
VT+ T+ V ++W P Q G ++ Y VE+ +
Sbjct: 619 APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
Query: 843 KGSNLWVPVNKD-PIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVK 901
G+ W VN + P++ + + L E Y FRV N AG G+PS + V D +
Sbjct: 678 AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
Query: 902 PPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT 961
P + S ++++S+ ++W E + GY +E + +W C P+ G+ +T
Sbjct: 738 IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFT 797
Query: 962 VGGLIERQKYFFRIRAVNEAGVGEPVELDKG--VRAMPPPAAPKFDLSA--RLKSHMVVR 1017
GL+ Q Y FR+RAVN AG+ E + + V+A P +P D++ + MV+
Sbjct: 798 CHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLG 857
Query: 1018 AGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILL 1077
I A + DGVP K RE K+ + + I++ K + +++
Sbjct: 858 WKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAA 917
Query: 1078 QNEFG-------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWN---HSPDVQEDGE 1127
N G + P PP +L+ E +++ L W HS G
Sbjct: 918 MNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTG- 976
Query: 1128 AHYIIMKR-DASTATWYTAAERVFSNKY-TVTGLLPGRKYYFRVVARNEIGDSEPLD 1182
+++ +K A W E N Y V GL G Y FRV A N+ G +P D
Sbjct: 977 -YFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 1032
Score = 148 bits (373), Expect = 4e-35
Identities = 237/1163 (20%), Positives = 428/1163 (36%), Gaps = 209/1163 (17%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR--MSA 319
P ++ W K P+ + + GKY ++ + L I+ + D Y S + + +SA
Sbjct: 304 PEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSA 363
Query: 320 ELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSE 379
+V+ + ++ GE + + + + +F E+ DDK++++
Sbjct: 364 YASVVVK--RYKGEFDETRF-HAGASTMPLSFGVTPYGYASRF---EIHFDDKFDVSFGR 417
Query: 380 DGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLE 439
+G T +L + + F E
Sbjct: 418 EGETMSLGCRVVITPEIKHFQPE------------------------------------- 440
Query: 440 CELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPT 499
++W ++G L G+RA L D G YT+ ++ G+
Sbjct: 441 ---------IQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTI-RVRMGEYY 490
Query: 500 EYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLK---DG----- 550
E YS + V+ +++ A +P ++ C+ N + + W + DG
Sbjct: 491 EQYSAYVF--------VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPIL 542
Query: 551 --------------KEITDLP--------------GMQIVKQGAVHKLI--FPS------ 574
+ D P I + AV+K+ FPS
Sbjct: 543 GYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPV 602
Query: 575 --MGPEHEGKYTFRAKG--------TESEASVFIADPPTIDPSVLEALAAHAITV--KVG 622
+ P + + R TE E S I P D SV EA ++ + G
Sbjct: 603 AALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPG 662
Query: 623 HTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVREDSGLILL 680
H + ++ + E E +RV+ E + + S +
Sbjct: 663 QRGH----------EGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRV 712
Query: 681 KLKNDHG------SATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
+ N G + T+ LD PK P G++ + + V + W+ KD + +
Sbjct: 713 RCSNSAGVGEPSEATEVTVVGDKLDIPKAP-GKIIPSRNTDTSVVVSWEESKD--AKELV 769
Query: 735 QFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSD-PLETEEV 793
+ +E G W K + F+ + + G++Y FR+ AVN+ G+S+ ++E +
Sbjct: 770 GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAI 829
Query: 794 FAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNL---WVP 850
I PP + ++++ + W P + GGA + GY V R+ + W
Sbjct: 830 EVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWRE 889
Query: 851 VNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD-PVKPPGLVQDL 909
N + + L E+ Y+F+V A+N AG G PS S ++ + PG L
Sbjct: 890 ANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSL 949
Query: 910 HVSDSSNSSISLAWREPAEGD--PPSGYILEMRAEDTKE--WSKCTKIPISGTCYTVGGL 965
S+ S+ L W+ P P +GY ++++ KE W + I V GL
Sbjct: 950 KCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGL 1009
Query: 966 IERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIH 1025
E Y FR+RA+N+AGVG+P +L V A P + ++ V G
Sbjct: 1010 KEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVN-------VDDDGVISLNF 1062
Query: 1026 AAFSGSPPPDVIWQKDGVPTKG--RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGE 1083
+P + W KD V T+ R + N ++ D G+Y + + G
Sbjct: 1063 ECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGI 1122
Query: 1084 ARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHS-PDVQEDGEAHYIIMKRDASTATW 1142
A + L EE+ + L+ H P V E I+++ +
Sbjct: 1123 A--------------SSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEK--GQVRF 1166
Query: 1143 YTAAERVFSNK-----YTVTGLLPGRKYYFRVVARNEIGD--SEPLDSRDTWLINKDQIQ 1195
+ AE++ N + + G KY + I + E L D Q+Q
Sbjct: 1167 WMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYT-FQLQ 1225
Query: 1196 DLSA-----------------KLKPYEKKDW--RHAPRFVTPLKPHTVLRGQDCTMTCAF 1236
D A K +++++W + P FV L V + + C
Sbjct: 1226 DGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLS-WEVTGECNVLLKCKV 1284
Query: 1237 LGNPRPT-VTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDR 1295
+ T + YK + I+ + K ++ G+CTL+I + KD+G Y V+++++ GKD+
Sbjct: 1285 ANIKKETHIVWYKDEREISVDEK--HDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDK 1342
Query: 1296 SSCTLTVYDKDDKSVVASITESL 1318
S L + D+ K ++ + + +
Sbjct: 1343 S--RLKLVDEAFKELMMEVCKKI 1363
Score = 52.4 bits (124), Expect = 3e-06
Identities = 100/485 (20%), Positives = 178/485 (36%), Gaps = 74/485 (15%)
Query: 283 KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEP-----LKFLGEMK-- 335
+ +V+ G K + ++ M+D GIYS V D A ++DE L E K
Sbjct: 1087 RLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFP 1146
Query: 336 --PVK------VTERQTAVFEIRLSKKEPNFV--WKFNGKELKRDDKYEITVS------- 378
PVK + E+ F ++ K N + FN KE+ KY++ +
Sbjct: 1147 TVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIE 1206
Query: 379 --------EDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLT--------IDRIPIKFV 422
ED T+T +++D + ++ G++ +K Q I + FV
Sbjct: 1207 MFMEKLQDEDEGTYTFQLQDGKATNHSTVVL-VGDVFKKLQKEAEFQRQEWIRKQGPHFV 1265
Query: 423 SNLKNVRVKERSRACLECELTS--KDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDA 480
L + V L+C++ + K+ + W KD + + K+ + L+I +
Sbjct: 1266 EYL-SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEF 1322
Query: 481 QLSDGGEYTVVAMQDGDPT--------EYYSTAIVTVEERLATVKSGMSDVHAATGSPAE 532
D G Y V+ D E + ++ V +++A + + A G
Sbjct: 1323 SKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY 1382
Query: 533 LCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA-KGTE 591
V E ++ W +G I ++ G L P +GKY G
Sbjct: 1383 SFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKT 1442
Query: 592 SEASVFIADPPTIDPSVLE-------ALAAH-----------AITVKVGHTAHIKVPFRG 633
D + E A+A +T++ G ++ G
Sbjct: 1443 GHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWG 1502
Query: 634 KPLPKVTWYKDGMEVTEEERVSME-RGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
P P+V+W K+ + ++ +++ A TI+ DSG L +KN +GS T+
Sbjct: 1503 DPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSD 1562
Query: 693 LHLSV 697
+SV
Sbjct: 1563 FTVSV 1567
Score = 50.8 bits (120), Expect = 8e-06
Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDV--NITAN-SKFWYNSTSGV 1267
HAP F+ + HTV ++ + C+ G P P VT YK V N+ AN K+ S G+
Sbjct: 275 HAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGM 334
Query: 1268 CTLVIPTCTLKDSGDYSVLVENELGK 1293
TL I C +D+ Y N G+
Sbjct: 335 HTLEINGCDFEDTAQYRASAMNVKGE 360
Score = 42.7 bits (99), Expect = 0.002
Identities = 31/107 (28%), Positives = 58/107 (54%), Gaps = 10/107 (9%)
Query: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA----NSKFWYNSTSGVCTLVIPTCTLK 1278
T+ G+ +TC G+P P V+ K + + + N KF T+ I +
Sbjct: 1487 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTA---YFTINGVSTA 1543
Query: 1279 DSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQ--KKSK 1323
DSG Y ++V+N+ G + S T++V+ ++++ +A++ ESL+ KK+K
Sbjct: 1544 DSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAAL-ESLKGGKKAK 1589
Score = 39.3 bits (90), Expect = 0.025
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT---KSKNHSQFLINSTKRSDS 1070
+ ++ G AL + G PPP+V W K+ + ++ + F IN +DS
Sbjct: 1486 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1545
Query: 1071 GVYRILLQNEFGEARYDIHVRV 1092
G Y ++++N++G D V V
Sbjct: 1546 GKYGLVVKNKYGSETSDFTVSV 1567
Score = 36.2 bits (82), Expect = 0.21
Identities = 74/346 (21%), Positives = 138/346 (39%), Gaps = 57/346 (16%)
Query: 223 KEMKKKVEV---EAIRILKPLEDKETKVDTTVVFDCIMELKDPNVK----MIWIKGTEPL 275
K+++K+ E E IR P + + T + +++ K N+K ++W K +
Sbjct: 1243 KKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREI 1302
Query: 276 RIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR--MSAELTVLDEPLKFLGE 333
+ K+D K L+I+ + DAGIY + + D R + L ++DE K L
Sbjct: 1303 SVDE---KHDFKD--GICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1357
Query: 334 MKPVKVT------ERQTAVFEIRLSKKEPNFV------WKFNGKELKRDDKYEITVSEDG 381
K+ + Q+ I+L +V W NG ++ D+ + V+ +
Sbjct: 1358 EVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQ 1417
Query: 382 LTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKF------VSNLKNVRVKERSR 435
+ L+I + +D G++ E + Q T+D + LK + E++R
Sbjct: 1418 I--WLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR 1475
Query: 436 A------------------CLECEL-TSKDVTLRWKKDGQLLMHGTKYSMNHE-GKRAEL 475
A L C + + W K+ + L ++ E G+ A
Sbjct: 1476 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYF 1535
Query: 476 IIEDAQLSDGGEY-TVVAMQDGDPTEYYSTAIVTVEE--RLATVKS 518
I +D G+Y VV + G T ++ ++ EE R+A ++S
Sbjct: 1536 TINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALES 1581
Score = 35.8 bits (81), Expect = 0.28
Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 18/172 (10%)
Query: 11 QEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIV-----EFFSL-----VTRSSNI 60
Q S + ++S V + T+ + EE +KS +V E SL T + +
Sbjct: 207 QSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHA 266
Query: 61 PAGDS----VPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA---K 113
+ PEF+ KP+ T E + + G +P ++W + +PI A K
Sbjct: 267 KLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQ-VPINVHANPGK 325
Query: 114 IFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMD 165
+S H L++ +D+ Y+ A N + S++V + + D
Sbjct: 326 YIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFD 377
Score = 30.8 bits (68), Expect = 9.0
Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 8/88 (9%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-----TKGRETITKSK 1055
AP+F + R SH V +H + +G P P V W K+ VP G+ I
Sbjct: 276 APEFIIKPR--SHTVWEKENVK-LHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY 332
Query: 1056 NHSQFLINSTKRSDSGVYRILLQNEFGE 1083
IN D+ YR N GE
Sbjct: 333 GMHTLEINGCDFEDTAQYRASAMNVKGE 360
>gi|55956914 myosin binding protein H [Homo sapiens]
Length = 477
Score = 186 bits (473), Expect = 1e-46
Identities = 126/423 (29%), Positives = 190/423 (44%), Gaps = 10/423 (2%)
Query: 887 PSVPSSSVVAKDPVKP----PGLVQDLHVSDSSNSSISLAWREPAEGDPPS--GYILEMR 940
P P++S K P P P L + D S+SS++++W P GY+LE+
Sbjct: 52 PQAPTASTATK-PAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC 110
Query: 941 AEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPA 1000
E EW + P+ T TV L K+ R+ AV+ AG G P LD+ +
Sbjct: 111 REGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
APK + L+ + + G + + F G P P W +G + ++ +
Sbjct: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
Query: 1061 L-INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHS 1119
L I S +RSDSG Y + ++ E EA+ I + V + P PP+++RL + L W
Sbjct: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
Query: 1120 PDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
D Y++ K D T W+T ER T++ L+ G Y FRV + N G S
Sbjct: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS- 349
Query: 1180 PLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGN 1239
+ T + Q D++AK K + ++D+ AP F PL HT G + C+ +
Sbjct: 350 -TSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
Query: 1240 PRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCT 1299
P+P + K + I N K+ S GVCTL I + DSG Y+ N LG+ C
Sbjct: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
Query: 1300 LTV 1302
L V
Sbjct: 469 LEV 471
Score = 85.9 bits (211), Expect = 2e-16
Identities = 47/166 (28%), Positives = 88/166 (53%), Gaps = 3/166 (1%)
Query: 620 KVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLIL 679
+VG T ++++PF+GKP P+ TW +G + +RVSM G+ ++L I + R DSG
Sbjct: 187 QVGETVNLQIPFQGKPKPQATWTHNG-HALDSQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
Query: 680 LKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVE 739
L ++ + A A + + V+++P PP + L++ G ++W P+D G + ++V+
Sbjct: 246 LTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ 304
Query: 740 RRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVS 785
+ W + E T + + + G +Y FR+ + N G+S
Sbjct: 305 KADKKTGQWFTVLE-RYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Score = 63.5 bits (153), Expect = 1e-09
Identities = 98/476 (20%), Positives = 162/476 (34%), Gaps = 49/476 (10%)
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
E T E + E + +S RE+ ++ A S +P PP
Sbjct: 15 EETASESAKVPTAEPPGEVAVSESTREE------QVPKPQAPAPQAPTASTATKPAPPSE 68
Query: 707 RVEFLEL-------SGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVT 759
V L S S V + W+ P+ G + +++E G W+ + VT
Sbjct: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
Query: 760 NFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAV 818
+ + G + R+ AV+S G P ++ + IE P + V
Sbjct: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
Query: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
T N G P K W N + + ++ +D+ R
Sbjct: 189 GETVNLQIPFQGKP----------KPQATWTH-NGHALDSQRVSMRTGDQDSILFIRSAQ 237
Query: 879 VNKAGPGQPSVPSSSVVAKD-----PVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPS 933
+ +G + +V + AK ++ PG + + D + +L W P +
Sbjct: 238 RSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTE 297
Query: 934 --GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVG------- 984
GY+++ + T +W + TC T+ LI Y FR+ + N G+
Sbjct: 298 LLGYMVQKADKKTGQWFTVLERYHPTTC-TISDLIIGNSYSFRVFSENLCGLSTSATVTK 356
Query: 985 EPVELDKGVRAMPPPAAPKFDLSAR------LKSHMVVRAGTALCIHAAFSGSPPPDVIW 1038
E + K A P + D S L H G + + + SP P +IW
Sbjct: 357 ELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADH-TSTPGYSTQLFCSVRASPKPKIIW 415
Query: 1039 QKDGVPTKGRETITKSKNHSQFLINSTKRS--DSGVYRILLQNEFGEARYDIHVRV 1092
K+ + +G + K S DSGVY N GEA D + V
Sbjct: 416 MKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
Score = 36.6 bits (83), Expect = 0.16
Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALL 665
PS + LA H T G++ + R P PK+ W K+ ME+ + + L
Sbjct: 382 PSFTQPLADHTSTP--GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
Query: 666 TISNCVREDSGLILLKLKNDHGSATATLHLSV 697
I DSG+ K N G A+ L V
Sbjct: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
>gi|140560919 myomesin 1 isoform a [Homo sapiens]
Length = 1685
Score = 170 bits (431), Expect = 7e-42
Identities = 146/599 (24%), Positives = 254/599 (42%), Gaps = 70/599 (11%)
Query: 637 PKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLS 696
P++ WY++G+ ++ + V ++A LT S+ +ED GL ++++ + ++
Sbjct: 439 PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
Query: 697 VLDRPKPPQGR------VEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK 750
V D +G V+ LE + + + WK P +GG P+ + +++ VG SW +
Sbjct: 499 VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
Query: 751 IGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQ 809
+ K F + EG++Y FR+ AVN G+ P E V A +P E S+P
Sbjct: 559 CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
Query: 810 ---------------------------VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRK 842
VT+ T+ V ++W P Q G ++ Y VE+ +
Sbjct: 619 APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
Query: 843 KGSNLWVPVNKD-PIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVK 901
G+ W VN + P++ + + L E Y FRV N AG G+PS + V D +
Sbjct: 678 AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
Query: 902 PPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT 961
P + S ++++S+ ++W E + GY +E + +W C P+ G+ +T
Sbjct: 738 IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFT 797
Query: 962 VGGLIERQKYFFRIRAVNEAGVGEPVELDKGVR---AMPPPAAPKFDLSARLKSHMVVRA 1018
GL+ Q Y FR+RAVN AG+ E + + + A+ +P D+ L
Sbjct: 798 CHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSP--DVCPALSDEPGGLT 855
Query: 1019 GTALCIHAAFSGSPPPDVIWQKDG-VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILL 1077
+ +H A SPP +QKD + +K + S + + +K S++ +
Sbjct: 856 ASRGRVHEA---SPP---TFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSET------V 903
Query: 1078 QNEF----------GEARYDIHVRVADF--PRPPTNLRLFEEVPNTVTLTWNHSPDVQED 1125
Q E G+++ D + D P PP ++ E +++ L W +
Sbjct: 904 QEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGA 963
Query: 1126 GEAHYIIMKR---DASTATWYTAAERVFSNK-YTVTGLLPGRKYYFRVVARNEIGDSEP 1180
Y + R D W A + S + Y ++ L Y F+V A N G P
Sbjct: 964 EITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAP 1022
Score = 115 bits (289), Expect = 2e-25
Identities = 134/579 (23%), Positives = 230/579 (39%), Gaps = 72/579 (12%)
Query: 778 AVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYI 837
A + SDPL+ + A PP + ++++ + W P + GGA + GY
Sbjct: 915 APQGKSKSDPLKKKTDRA-----PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYY 969
Query: 838 VERRKKGSNL---WVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSV 894
V R+ + W N + + L E+ Y+F+V A+N AG G PS S
Sbjct: 970 VNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECF 1029
Query: 895 VAKD-PVKPPGLVQDLHVSDSSNSSISLAWREPAEGD--PPSGYILEMRAEDTKE--WSK 949
++ + PG L S+ S+ L W+ P P +GY ++++ KE W
Sbjct: 1030 KCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRG 1089
Query: 950 CTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSAR 1009
+ I V GL E Y FR+RA+N+AGVG+P +L V A P + ++
Sbjct: 1090 LNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVN-- 1147
Query: 1010 LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKG--RETITKSKNHSQFLINSTKR 1067
V G +P + W KD V T+ R + N ++
Sbjct: 1148 -----VDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGM 1202
Query: 1068 SDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHS-PDVQEDG 1126
D G+Y + + G A + L EE+ + L+ H P V
Sbjct: 1203 DDLGIYSCDVTDTDGIA--------------SSYLIDEEELKRLLALSHEHKFPTVPVKS 1248
Query: 1127 EAHYIIMKRDASTATWYTAAERVFSNK-----YTVTGLLPGRKYYFRVVARNEIGD--SE 1179
E I+++ ++ AE++ N + + G KY + I + E
Sbjct: 1249 ELAVEILEK--GQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFME 1306
Query: 1180 PLDSRDTWLINKDQIQDLSA-----------------KLKPYEKKDW--RHAPRFVTPLK 1220
L D Q+QD A K +++++W + P FV L
Sbjct: 1307 KLQDEDEGTYT-FQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLS 1365
Query: 1221 PHTVLRGQDCTMTCAFLGNPRPT-VTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKD 1279
V + + C + T + YK + I+ + K ++ G+CTL+I + KD
Sbjct: 1366 -WEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEK--HDFKDGICTLLITEFSKKD 1422
Query: 1280 SGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESL 1318
+G Y V+++++ GKD+S L + D+ K ++ + + +
Sbjct: 1423 AGIYEVILKDDRGKDKS--RLKLVDEAFKELMMEVCKKI 1459
Score = 88.6 bits (218), Expect = 4e-17
Identities = 61/204 (29%), Positives = 94/204 (46%), Gaps = 7/204 (3%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P + LE + + WK P GG +T + V R V K E + K +
Sbjct: 933 PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVS 992
Query: 761 ---FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNP--IEPPGFASQPQVTDVTK 815
+ + ++E YQF++ A+N G+ P E F I PG + ++V K
Sbjct: 993 EEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRK 1052
Query: 816 EAVTITWNAPTQDGGAPVLGYIVERR--KKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYE 873
+++ + W P G PV GY V+ + K + W +N+ I+ V GL E Y
Sbjct: 1053 DSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYV 1112
Query: 874 FRVIAVNKAGPGQPSVPSSSVVAK 897
FRV A+N+AG G+PS + VVA+
Sbjct: 1113 FRVRAINQAGVGKPSDLAGPVVAE 1136
Score = 64.7 bits (156), Expect = 6e-10
Identities = 154/805 (19%), Positives = 276/805 (34%), Gaps = 166/805 (20%)
Query: 262 PNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR--MSA 319
P ++ W K P+ + + GKY ++ + L I+ + D Y S + + +SA
Sbjct: 304 PEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSA 363
Query: 320 ELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSE 379
+V+ + ++ GE + + + + +F E+ DDK++++
Sbjct: 364 YASVVVK--RYKGEFDETRF-HAGASTMPLSFGVTPYGYASRF---EIHFDDKFDVSFGR 417
Query: 380 DGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLE 439
+G T +L + + F E
Sbjct: 418 EGETMSLGCRVVITPEIKHFQPE------------------------------------- 440
Query: 440 CELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPT 499
++W ++G L G+RA L D G YT + ++ G+
Sbjct: 441 ---------IQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYT-IRVRMGEYY 490
Query: 500 EYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLK---DG----- 550
E YS + V+ +++ A +P ++ C+ N + + W + DG
Sbjct: 491 EQYSAYVF--------VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPIL 542
Query: 551 --------------KEITDLP--------------GMQIVKQGAVHK--LIFPS------ 574
+ D P I + AV+K + FPS
Sbjct: 543 GYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPV 602
Query: 575 --MGPEHEGKYTFRAKG--------TESEASVFIADPPTIDPSVLEALAAHAIT--VKVG 622
+ P + + R TE E S I P D SV EA ++ + G
Sbjct: 603 AALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPG 662
Query: 623 HTAHIKVPFRGKPLPKVTWYKDGMEVTEE--ERVSMERGEDQALLTISNCVREDSGLILL 680
H + ++ + E E +RV+ E + + S +
Sbjct: 663 QRGH----------EGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRV 712
Query: 681 KLKNDHG------SATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
+ N G + T+ LD PK P G++ + + V + W+ KD + +
Sbjct: 713 RCSNSAGVGEPSEATEVTVVGDKLDIPKAP-GKIIPSRNTDTSVVVSWEESKD--AKELV 769
Query: 735 QFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVF 794
+ +E G W K + F+ + + G++Y FR+ AVN+ G+S+ + E
Sbjct: 770 GYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAI 829
Query: 795 -----AGNPIEP---PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSN 846
G + P P + +P ++ V + PT A + GS
Sbjct: 830 EVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEA-SPPTFQKDALL----------GSK 878
Query: 847 LWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLV 906
P Q T + +T E KA P Q S + K PP
Sbjct: 879 PNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAP-QGKSKSDPLKKKTDRAPPSPP 937
Query: 907 QDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRA---EDTKEWSKCTKIPISGTCYT 961
D+ +S S+ L W++P + G +GY + R +W + +S Y
Sbjct: 938 CDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYK 997
Query: 962 VGGLIERQKYFFRIRAVNEAGVGEP 986
+ L E Y F++ A+N AG+G P
Sbjct: 998 ISNLKENMVYQFQVAAMNMAGLGAP 1022
Score = 52.4 bits (124), Expect = 3e-06
Identities = 100/485 (20%), Positives = 178/485 (36%), Gaps = 74/485 (15%)
Query: 283 KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEP-----LKFLGEMK-- 335
+ +V+ G K + ++ M+D GIYS V D A ++DE L E K
Sbjct: 1183 RLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFP 1242
Query: 336 --PVK------VTERQTAVFEIRLSKKEPNFV--WKFNGKELKRDDKYEITVS------- 378
PVK + E+ F ++ K N + FN KE+ KY++ +
Sbjct: 1243 TVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIE 1302
Query: 379 --------EDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLT--------IDRIPIKFV 422
ED T+T +++D + ++ G++ +K Q I + FV
Sbjct: 1303 MFMEKLQDEDEGTYTFQLQDGKATNHSTVVL-VGDVFKKLQKEAEFQRQEWIRKQGPHFV 1361
Query: 423 SNLKNVRVKERSRACLECELTS--KDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDA 480
L + V L+C++ + K+ + W KD + + K+ + L+I +
Sbjct: 1362 EYL-SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEF 1418
Query: 481 QLSDGGEYTVVAMQDGDPT--------EYYSTAIVTVEERLATVKSGMSDVHAATGSPAE 532
D G Y V+ D E + ++ V +++A + + A G
Sbjct: 1419 SKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLY 1478
Query: 533 LCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRA-KGTE 591
V E ++ W +G I ++ G L P +GKY G
Sbjct: 1479 SFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKT 1538
Query: 592 SEASVFIADPPTIDPSVLE-------ALAAH-----------AITVKVGHTAHIKVPFRG 633
D + E A+A +T++ G ++ G
Sbjct: 1539 GHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWG 1598
Query: 634 KPLPKVTWYKDGMEVTEEERVSME-RGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
P P+V+W K+ + ++ +++ A TI+ DSG L +KN +GS T+
Sbjct: 1599 DPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSD 1658
Query: 693 LHLSV 697
+SV
Sbjct: 1659 FTVSV 1663
Score = 51.2 bits (121), Expect = 6e-06
Identities = 44/190 (23%), Positives = 77/190 (40%), Gaps = 21/190 (11%)
Query: 1034 PDVIWQKDGVPTKGRETITK--SKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091
P++ W ++GVP + + S + + + D G+Y I ++ +Y +V
Sbjct: 439 PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
Query: 1092 VADF-------PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYT 1144
V D P P +++ E + + ++W Y I K + T +W
Sbjct: 499 VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
Query: 1145 AAER-VFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203
+ V ++ VTGL+ GR Y FRV A N++G P ++ + A L P
Sbjct: 559 CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFP-----------SRVSEPVAALDP 607
Query: 1204 YEKKDWRHAP 1213
EK + P
Sbjct: 608 AEKARLKSRP 617
Score = 50.8 bits (120), Expect = 8e-06
Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Query: 1211 HAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDV--NITAN-SKFWYNSTSGV 1267
HAP F+ + HTV ++ + C+ G P P VT YK V N+ AN K+ S G+
Sbjct: 275 HAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGM 334
Query: 1268 CTLVIPTCTLKDSGDYSVLVENELGK 1293
TL I C +D+ Y N G+
Sbjct: 335 HTLEINGCDFEDTAQYRASAMNVKGE 360
Score = 44.7 bits (104), Expect = 6e-04
Identities = 32/116 (27%), Positives = 50/116 (43%), Gaps = 4/116 (3%)
Query: 1096 PRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAER--VFSNK 1153
P PPT+L + E + V L+W +G Y + K +A T W V S +
Sbjct: 638 PGPPTDLSVTEATRSYVVLSWKPPGQRGHEG-IMYFVEKCEAGTENWQRVNTELPVKSPR 696
Query: 1154 YTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLI-NKDQIQDLSAKLKPYEKKD 1208
+ + L G+ Y FRV N G EP ++ + ++ +K I K+ P D
Sbjct: 697 FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTD 752
Score = 42.7 bits (99), Expect = 0.002
Identities = 31/107 (28%), Positives = 58/107 (54%), Gaps = 10/107 (9%)
Query: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITA----NSKFWYNSTSGVCTLVIPTCTLK 1278
T+ G+ +TC G+P P V+ K + + + N KF T+ I +
Sbjct: 1583 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTA---YFTINGVSTA 1639
Query: 1279 DSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQ--KKSK 1323
DSG Y ++V+N+ G + S T++V+ ++++ +A++ ESL+ KK+K
Sbjct: 1640 DSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAAL-ESLKGGKKAK 1685
Score = 42.4 bits (98), Expect = 0.003
Identities = 62/294 (21%), Positives = 114/294 (38%), Gaps = 46/294 (15%)
Query: 439 ECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDP 498
EC+ + W KD + + +G + ++ +D + D G Y+ D
Sbjct: 1159 ECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSC----DVTD 1214
Query: 499 TEYYSTAIVTVEERLATVKSGMSDVHAATGSP--AELCVVLNDEKVEGVWLK-------- 548
T+ +++ + EE L + + +S H P +EL V + ++ W++
Sbjct: 1215 TDGIASSYLIDEEELKRLLA-LSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNA 1273
Query: 549 ------DGKEITDLP--GMQIVKQGAVHKLIFPSMGPEHEGKYTFR---AKGTESEASVF 597
+ KEI + P M I + + ++ + E EG YTF+ K T V
Sbjct: 1274 KVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1333
Query: 598 IADP----------------PTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW 641
+ D P +E L + +T + KV K + W
Sbjct: 1334 VGDVFKKLQKEAEFQRQEWIRKQGPHFVEYL-SWEVTGECNVLLKCKVA-NIKKETHIVW 1391
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHL 695
YKD E++ +E+ + G L I+ ++D+G+ + LK+D G + L L
Sbjct: 1392 YKDEREISVDEKHDFKDG--ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443
Score = 39.3 bits (90), Expect = 0.025
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETIT---KSKNHSQFLINSTKRSDS 1070
+ ++ G AL + G PPP+V W K+ + ++ + F IN +DS
Sbjct: 1582 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADS 1641
Query: 1071 GVYRILLQNEFGEARYDIHVRV 1092
G Y ++++N++G D V V
Sbjct: 1642 GKYGLVVKNKYGSETSDFTVSV 1663
Score = 36.2 bits (82), Expect = 0.21
Identities = 74/346 (21%), Positives = 138/346 (39%), Gaps = 57/346 (16%)
Query: 223 KEMKKKVEV---EAIRILKPLEDKETKVDTTVVFDCIMELKDPNVK----MIWIKGTEPL 275
K+++K+ E E IR P + + T + +++ K N+K ++W K +
Sbjct: 1339 KKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREI 1398
Query: 276 RIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR--MSAELTVLDEPLKFLGE 333
+ K+D K L+I+ + DAGIY + + D R + L ++DE K L
Sbjct: 1399 SVDE---KHDFKD--GICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMM 1453
Query: 334 MKPVKVT------ERQTAVFEIRLSKKEPNFV------WKFNGKELKRDDKYEITVSEDG 381
K+ + Q+ I+L +V W NG ++ D+ + V+ +
Sbjct: 1454 EVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQ 1513
Query: 382 LTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKF------VSNLKNVRVKERSR 435
+ L+I + +D G++ E + Q T+D + LK + E++R
Sbjct: 1514 I--WLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNR 1571
Query: 436 A------------------CLECEL-TSKDVTLRWKKDGQLLMHGTKYSMNHE-GKRAEL 475
A L C + + W K+ + L ++ E G+ A
Sbjct: 1572 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYF 1631
Query: 476 IIEDAQLSDGGEY-TVVAMQDGDPTEYYSTAIVTVEE--RLATVKS 518
I +D G+Y VV + G T ++ ++ EE R+A ++S
Sbjct: 1632 TINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALES 1677
Score = 35.8 bits (81), Expect = 0.28
Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 18/172 (10%)
Query: 11 QEHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIV-----EFFSL-----VTRSSNI 60
Q S + ++S V + T+ + EE +KS +V E SL T + +
Sbjct: 207 QSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHA 266
Query: 61 PAGDS----VPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA---K 113
+ PEF+ KP+ T E + + G +P ++W + +PI A K
Sbjct: 267 KLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQ-VPINVHANPGK 325
Query: 114 IFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMD 165
+S H L++ +D+ Y+ A N + S++V + + D
Sbjct: 326 YIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFD 377
Score = 30.8 bits (68), Expect = 9.0
Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 8/88 (9%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-----TKGRETITKSK 1055
AP+F + R SH V +H + +G P P V W K+ VP G+ I
Sbjct: 276 APEFIIKPR--SHTVWEKENVK-LHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRY 332
Query: 1056 NHSQFLINSTKRSDSGVYRILLQNEFGE 1083
IN D+ YR N GE
Sbjct: 333 GMHTLEINGCDFEDTAQYRASAMNVKGE 360
>gi|156104903 myomesin 2 [Homo sapiens]
Length = 1465
Score = 168 bits (426), Expect = 3e-41
Identities = 136/597 (22%), Positives = 239/597 (40%), Gaps = 45/597 (7%)
Query: 637 PKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLS 696
P+ WY+D + + E + M GE QA L+ S+ ++D GL L++ + G + + L
Sbjct: 312 PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLF 371
Query: 697 VLDRPKPPQGR------VEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIK 750
V D G ++ + + V + WK P PV + V+R VG +W++
Sbjct: 372 VRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQ 431
Query: 751 IGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAG-NPIE--------- 800
+ K+ + + EG++Y FR+ AVNS G+S P + A +P++
Sbjct: 432 CNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHL 491
Query: 801 ------------------PPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRK 842
PG + +++++ V ++W PT G P++ Y +E+
Sbjct: 492 EGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSV 550
Query: 843 KGSNLWVPVN-KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVK 901
GS W VN + ++ + V L+E Y FRV++ N+ G +PS +S + A+D
Sbjct: 551 VGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTV 610
Query: 902 PPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYT 961
P + S ++ +S+ + W P + GY ++ T W C PI +
Sbjct: 611 VPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFV 670
Query: 962 VGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTA 1021
V GL ++Y FR++AVN G+ E + ++ P L +
Sbjct: 671 VHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLG 730
Query: 1022 LCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL-INSTKRSDSGVYRILLQNE 1080
+ GSP K V K + S + L ++ ++I N
Sbjct: 731 WKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNL 790
Query: 1081 FG-------EARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIM 1133
G + P P +L E ++ + W + Y +
Sbjct: 791 AGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVD 850
Query: 1134 KRDASTATWYTAAERVFSNKY-TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLI 1189
R+ W T + +N+Y V+ L G+ Y FRV A N G +P D+ + L+
Sbjct: 851 FREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLV 907
Score = 152 bits (383), Expect = 3e-36
Identities = 153/646 (23%), Positives = 259/646 (40%), Gaps = 78/646 (12%)
Query: 701 PKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTN 760
P P GRV + + V ++W PK + + V+ G W
Sbjct: 612 PSAP-GRVLASRNTKTSVVVQWDRPKHE--EDLLGYYVDCCVAGTNLWEPCNHKPIGYNR 668
Query: 761 FSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGN-----PIEPPGFASQPQVTDVTK 815
F + + G+ Y FR+ AVN+ G+S+ + +V P P G + +
Sbjct: 669 FVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGIT----LLNCDG 724
Query: 816 EAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFR 875
++T+ W P GG+P+LGY +++R+ W VN P + T TVDGL E + YEF+
Sbjct: 725 HSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFK 784
Query: 876 VIAVNKAGPGQPSVPSSSVVAKDPVKP-PGLVQDLHVSDSSNSSISLAWREP--AEGDPP 932
+ AVN AG G+PS PS + P PG DL + ++S+ + W+ P + P
Sbjct: 785 IAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPV 844
Query: 933 SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKG 992
SGY ++ R ED EW + + V L + + Y FR+RAVN GVG+P + +
Sbjct: 845 SGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904
Query: 993 VRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDV---IWQK--DGVPTKG 1047
V P + + + I+ F D W K + +
Sbjct: 905 VLVEARPGTKEISAGVDEQGN----------IYLGFDCQEMTDASQFTWCKSYEEISDDE 954
Query: 1048 RETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLR---- 1103
R I +HS+ + + + D G Y + + + G + + F P L
Sbjct: 955 RFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVS--------SSFVLDPEELERLMA 1006
Query: 1104 LFEEVPN-TVTLT---------------WNHSPDVQEDGEAHYIIMKRDASTATWYTAAE 1147
L E+ N T+ L W + + D +II R+ S +
Sbjct: 1007 LSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSD----SEIH 1062
Query: 1148 RVFSNKYTVTGLLPGRKYYFRVVARN----EIGDSEPLDSRDTWLIN---KDQIQDLSAK 1200
R+ +K TG++ F + +I D + LI K +++ +
Sbjct: 1063 RIKCDK--ATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQ 1120
Query: 1201 LKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFW 1260
K + +K H ++ V + + C + TV + D ++ ++
Sbjct: 1121 RKEFLRKQGPHFAEYL----HWDVTEECEVRLVCKVANTKKETVFKWLKD-DVLYETETL 1175
Query: 1261 YNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLT--VYD 1304
N G+C L+IP + KD G+Y ++++ G+D S + VYD
Sbjct: 1176 PNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYD 1221
Score = 133 bits (335), Expect = 1e-30
Identities = 160/665 (24%), Positives = 258/665 (38%), Gaps = 108/665 (16%)
Query: 606 PSVLEALAAHAITVKVGHTAHIKVPF--RGKPLPKVTWYKDG---MEVTEEERVSMERGE 660
P +L L +H + ++ +K+ F +G P P V WYKDG + E + +E
Sbjct: 154 PEILVRLRSHTVWERMS----VKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNY 209
Query: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVL-----DRPKPPQG--------- 706
L I+ +D+ N HG + + V + P G
Sbjct: 210 GVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSS 269
Query: 707 -------RVEFLE-------LSGSCVHMKWK---APKDNGGRPVTQFIVERRAVGKKSWI 749
V+FLE G V +K P +P ++ + + + W
Sbjct: 270 MIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWT 329
Query: 750 KI--GEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPI--EPPGFA 805
K+ GE ++ +K +EG Y RI V+ GVSD V +P+ PG
Sbjct: 330 KMFFGEGQASLSFSHLHKDDEG-LYTLRI--VSRGGVSDHSAFLFVRDADPLVTGAPGAP 386
Query: 806 SQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDG 865
Q D ++ V +TW P +PV+GY V+R + G+N WV N P++ K V G
Sbjct: 387 MDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTG 446
Query: 866 LLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPV------------------------- 900
L E Y FRV AVN AG +PS S +V A DP+
Sbjct: 447 LFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEG 506
Query: 901 --KPPGLVQDLHVSDSSNSSISLAWREPA-EGDPPSGYILEMRAEDTKEWSKC-TKIPIS 956
+ PG +H S+ S + + L+W P G P Y +E + W + + +
Sbjct: 507 DAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVR 566
Query: 957 GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMP---PPAAPKFDLSAR-LKS 1012
Y V L+E + Y FR+ + N G+ EP E+ ++A P+AP L++R K+
Sbjct: 567 SPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKT 626
Query: 1013 HMVVRAG--------TALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINS 1064
+VV+ + +G+ +W+ K +++F+++
Sbjct: 627 SVVVQWDRPKHEEDLLGYYVDCCVAGTN----LWEPCN---------HKPIGYNRFVVHG 673
Query: 1065 TKRSDSGVYRILLQNEFGEARYD-----IHVRVA-DFPRPPTNLRLFEEVPNTVTLTWNH 1118
+ ++R+ N G + I V+ A P P + L +++TL W
Sbjct: 674 LTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKV 733
Query: 1119 SPDVQEDGEAHYIIMKRDASTATWYTA-AERVFSNKYTVTGLLPGRKYYFRVVARNEIGD 1177
Y + KR+ W+ + TV GL G Y F++ A N G
Sbjct: 734 PKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGI 793
Query: 1178 SEPLD 1182
EP D
Sbjct: 794 GEPSD 798
Score = 63.2 bits (152), Expect = 2e-09
Identities = 111/542 (20%), Positives = 197/542 (36%), Gaps = 88/542 (16%)
Query: 253 FDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSV 312
FDC E+ D + + W K E + ++ ++ +G L + N + D G YS+SV
Sbjct: 930 FDC-QEMTDAS-QFTWCKSYEEISDDE---RFKIETVGDHSKLYLKNPDKEDLGTYSVSV 984
Query: 313 GDKRMSAELTVLD-EPLKFL----GEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKEL 367
D + VLD E L+ L E+K + + +EI K F W + L
Sbjct: 985 SDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEI-FDKGRVRF-W-LQAEHL 1041
Query: 368 KRDDKYEITVSE----DGLTHTLKIKDAR-----------LSDSGEFSAEAGNLVQKAQL 412
D Y +++ D H +K A + + G ++ + + K+Q
Sbjct: 1042 SPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQS 1101
Query: 413 TIDRIPIKFVSNLKNVR---------------------VKERSRACLECEL--TSKDVTL 449
++ I F + L+ V E L C++ T K+
Sbjct: 1102 SLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVF 1161
Query: 450 RWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPT--------EY 501
+W KD +++ T+ N E EL+I D GEY D +
Sbjct: 1162 KWLKDD--VLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKV 1219
Query: 502 YSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQI 561
Y I+ + S + + G + + ++++ W +I+ M+I
Sbjct: 1220 YDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRI 1279
Query: 562 VKQGAVHKLIFPSMGPEHEGKYTFRA-KGTESEASVFIADPPTIDPSVLE----ALAAHA 616
+ L + +GKYTF G ++ D + E AA A
Sbjct: 1280 GGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFA 1339
Query: 617 --------------ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQ 662
+T+ G T ++ G P P+V W+K+ ++ E S++ + +
Sbjct: 1340 EKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK 1399
Query: 663 AL-LTISNCVREDSGLILLKLKNDHGSATATLHLSVL-------DRPKPPQGRVEFLELS 714
+ +TI EDSG + +KN +G + +SV D P Q + + + S
Sbjct: 1400 YVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPAS 1459
Query: 715 GS 716
S
Sbjct: 1460 AS 1461
Score = 52.8 bits (125), Expect = 2e-06
Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
Query: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN-STSGVCTLVIPTCTLKDSG 1281
T++ G+ +TC GNP P V +K D +I + F + ++ I T +DSG
Sbjct: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414
Query: 1282 DYSVLVENELGKDRSSCTLTVYDKDDK 1308
YS+ ++N+ G ++ T++VY +K
Sbjct: 1415 KYSINIKNKYGGEKIDVTVSVYKHGEK 1441
Score = 38.1 bits (87), Expect = 0.056
Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 4/128 (3%)
Query: 1178 SEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFL 1237
S+ D D + I + L+ + +E++ R AP + L+ HTV +
Sbjct: 120 SQARDKLDKYAIQQMMEDKLAWERHTFEERISR-APEILVRLRSHTVWERMSVKLCFTVQ 178
Query: 1238 GNPRPTVTLYKGDVNI---TANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKD 1294
G P P V YK I K+ S GV TL I D+ YS + N G+
Sbjct: 179 GFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQV 238
Query: 1295 RSSCTLTV 1302
++ + V
Sbjct: 239 STNAAVVV 246
Score = 37.7 bits (86), Expect = 0.074
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 1014 MVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL---INSTKRSDS 1070
+ + G L + G+P P+VIW K+ + E + ++++ I DS
Sbjct: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDS 1413
Query: 1071 GVYRILLQNEFGEARYDIHVRV 1092
G Y I ++N++G + D+ V V
Sbjct: 1414 GKYSINIKNKYGGEKIDVTVSV 1435
Score = 32.3 bits (72), Expect = 3.1
Identities = 24/103 (23%), Positives = 40/103 (38%), Gaps = 6/103 (5%)
Query: 508 TVEERLATVKSGMSDVHAATGSPAEL-----CVVLNDEKVEGVWLKDGKEITDLPGMQIV 562
T E L + G ++ A + C + D + W K +EI+D +I
Sbjct: 901 TSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDAS-QFTWCKSYEEISDDERFKIE 959
Query: 563 KQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID 605
G KL + E G Y+ T+ +S F+ DP ++
Sbjct: 960 TVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELE 1002
Score = 32.0 bits (71), Expect = 4.0
Identities = 28/117 (23%), Positives = 55/117 (47%), Gaps = 7/117 (5%)
Query: 580 EGK-YTFRAKGTESEASVFIADPPTIDPSVLEAL-AAHAITVKVGHTAHIKVPFRGKPLP 637
+GK Y FR + + +D T +P ++EA I+ V +I + F + +
Sbjct: 879 QGKTYVFRVRAVNANGVGKPSD--TSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMT 936
Query: 638 ---KVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATA 691
+ TW K E++++ER +E D + L + N +ED G + + + G +++
Sbjct: 937 DASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSS 993
Score = 32.0 bits (71), Expect = 4.0
Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 8/109 (7%)
Query: 73 PQPVTAPEGDKAVFRARVQGNAKPHISW-KRESGIPIKESAKIFYDSINKEHVLKLEPLT 131
P VT EG V GN P + W K + I + E + + K + ++ +T
Sbjct: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQA-KYVSMTIKGVT 1409
Query: 132 SDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKK 180
S+DS Y N + V++ V + EK + APP K
Sbjct: 1410 SEDSGKYSINIKNKYGGEKIDVTVSVYKHGEK------IPDMAPPQQAK 1452
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 165 bits (417), Expect = 3e-40
Identities = 157/655 (23%), Positives = 275/655 (41%), Gaps = 65/655 (9%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+F E + A EG AV R + A P WK + + + D E L++
Sbjct: 3627 KFTEGLRNEEATEGATAVLRCELSKMA-PVEWWKGHETLRDGDRHSLRQDGARCE--LQI 3683
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKM-----------LKKRAPP 176
L ++D+ Y C+ + A+ TV + ++ E + ++ L K AP
Sbjct: 3684 RGLVAEDAGEYLCMCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLWCELSKAAPV 3743
Query: 177 APKKKQKKVANEKE------------MLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKE 224
+K + + + + L+ V ++ VC + +
Sbjct: 3744 EWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQ-------------ER 3790
Query: 225 MKKKVEVEAI--RILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLG 282
+ V A+ R ++ ++++E + T V C + P + W KG+E LR
Sbjct: 3791 TSATLTVRALPARFIEDVKNQEAREGATAVLQCELSKAAP---VEWRKGSETLR---GGD 3844
Query: 283 KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTER 342
+Y ++Q GT+ L I +++ D G YS G +R SA LTV F ++ ++ E
Sbjct: 3845 RYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREPLQSLQAEEG 3904
Query: 343 QTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAE 402
TA + LS+ VW G +L+ + + E + G T L ++D + D+GE++
Sbjct: 3905 STATLQCELSEPTATVVWSKGGLQLQANGRREPRLQ--GCTAELVLQDLQREDTGEYTCT 3962
Query: 403 AGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGT 462
G+ A LT+ P++F+ L++ V E A L CEL+ ++ W+K L
Sbjct: 3963 CGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGSLQLFPCA 4022
Query: 463 KYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSD 522
KY M +G AEL++ + D G+YT D S A ++V K+ +
Sbjct: 4023 KYQMVQDGAAAELLVRGVEQEDAGDYTC------DTGHTQSMASLSVRVPRPKFKTRLQS 4076
Query: 523 VHAATGSPAELCVVLNDEKVEGV--WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHE 580
+ TG A LC L+D + V WLK+G E+ P ++ QGA +L+ + +
Sbjct: 4077 LEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDT 4136
Query: 581 GKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVT 640
G+Y G ++ AS+ + +P + +++ L +T +V G V
Sbjct: 4137 GEYACVTGGQKTAASLRVTEP---EVTIVRGLVDAEVTADEDVEFSCEVSRAG--ATGVQ 4191
Query: 641 WYKDGMEVTEEE--RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
W G+ + E V++ G L + ED+G + L N SA T+
Sbjct: 4192 WCLQGLPLQSNEVTEVAVRDGRIHT-LRLKGVTPEDAGTVSFHLGNHASSAQLTV 4245
Score = 152 bits (384), Expect = 2e-36
Identities = 124/464 (26%), Positives = 200/464 (43%), Gaps = 20/464 (4%)
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
+VE A + + LE ++ TV C EL +++W G LR+ ++ +
Sbjct: 1803 QVEEVAAKFCRLLEPVCGELGGTVTLAC--ELSPACAEVVWRCGNTQLRVGK---RFQMV 1857
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTV-LDEPLKFLGEMKPVKVTERQTAV 346
G L + + DAG Y D SA+LTV + +KF+ + V E A
Sbjct: 1858 AEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEAT 1917
Query: 347 FEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
F+ +S + VW +G L+ +K+ I S+ G +H+L I D L D+G+ + EA
Sbjct: 1918 FQCVVSPSDVAVVWFRDGALLQPSEKFAI--SQSGASHSLTISDLVLEDAGQITVEAEGA 1975
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
A L + P+ F L+ V+ERS LE ELT LRW ++ L G +
Sbjct: 1976 SSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEI 2035
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
+ EG R L++ + +D G + D + A +TVE R + G+ V A
Sbjct: 2036 HAEGARHRLVLHNVGFADRGFFGCETPDD------KTQAKLTVEMRQVRLVRGLQAVEAR 2089
Query: 527 TGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
A + V L+ V+G W +DG P + +G +H L + PE G F+
Sbjct: 2090 EQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFK 2149
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
A+G + A + + + P S L T K T ++ +P V W KDG+
Sbjct: 2150 AEGVHTSARLVVTELPV---SFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGV 2203
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSAT 690
E+ + +++ LTI C D G+ + + SA+
Sbjct: 2204 ELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSAS 2247
Score = 151 bits (382), Expect = 4e-36
Identities = 139/499 (27%), Positives = 221/499 (44%), Gaps = 35/499 (7%)
Query: 235 RILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYM 294
R ++ ++++E + T V C + P + W KG+E LR +Y ++Q GTK
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCELNSAAP---VEWRKGSETLR---DGDRYSLRQDGTKCE 3592
Query: 295 LVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKK 354
L I + M D G YS G +R SA LTV P+KF ++ + TE TAV LSK
Sbjct: 3593 LQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKM 3652
Query: 355 EPNFVWKFNGKELKRD-DKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLT 413
P WK G E RD D++ ++ +DG L+I+ D+GE+ G A LT
Sbjct: 3653 APVEWWK--GHETLRDGDRH--SLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLT 3708
Query: 414 IDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRA 473
+ +P KF+ L+N E A L CEL SK + W+K + L G ++S+ +G R
Sbjct: 3709 VRAMPSKFIEGLRNEEATEGDTATLWCEL-SKAAPVEWRKGHETLRDGDRHSLRQDGSRC 3767
Query: 474 ELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL 533
EL I + D GEY+ V Q+ ++A +TV A + + A G+ A L
Sbjct: 3768 ELQIRGLAVVDAGEYSCVCGQE------RTSATLTVRALPARFIEDVKNQEAREGATAVL 3821
Query: 534 -CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTES 592
C + VE W K + + + + G +L + G+Y+ +
Sbjct: 3822 QCELSKAAPVE--WRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERT 3879
Query: 593 EASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEE 652
A++ + P + L++L A + G TA ++ +P V W K G+++
Sbjct: 3880 SATLTVRAPQPVFREPLQSLQA-----EEGSTATLQCEL-SEPTATVVWSKGGLQLQANG 3933
Query: 653 RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL------HLSVLDRPKPPQG 706
R A L + + RED+G + SAT T+ L L + +G
Sbjct: 3934 RREPRLQGCTAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEG 3993
Query: 707 RVEFL--ELSGSCVHMKWK 723
L ELS + ++W+
Sbjct: 3994 GTAHLCCELSRAGASVEWR 4012
Score = 137 bits (344), Expect = 9e-32
Identities = 179/798 (22%), Positives = 293/798 (36%), Gaps = 106/798 (13%)
Query: 66 VPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVL 125
V +F+ V A EG +A F+ V + + W R+ + ++ S K H L
Sbjct: 1898 VVKFMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGAL-LQPSEKFAISQSGASHSL 1955
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKV 185
+ L +D+ A + A V + + KK+ P +++ V
Sbjct: 1956 TISDLVLEDAGQITVEAEGASSSAALRVR----------EAPVLFKKKLEPQTVEERSSV 2005
Query: 186 ANEKEMLE----------ILSKVPKKDFE---------KVCMEYGFTDFRGLLR-----K 221
E E+ + P K+ E V GF D RG
Sbjct: 2006 TLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFAD-RGFFGCETPDD 2064
Query: 222 LKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSL 281
+ K VE+ +R+++ L+ E + T + ++L +V W + + LR Q
Sbjct: 2065 KTQAKLTVEMRQVRLVRGLQAVEAREQGTATME--VQLSHADVDGSWTR--DGLRFQQGP 2120
Query: 282 GKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTE 341
+ + G + L +S + D+G+ SA L V + P+ F ++ V TE
Sbjct: 2121 TCH-LAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVVTTE 2179
Query: 342 RQTAVFEIRLSKKEPNFVWKFNGKELK--------------------------------- 368
++ E LS+ + W +G EL+
Sbjct: 2180 KEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDA 2239
Query: 369 RDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNV 428
D + +V G T+TL + D+GE A N +AQL + +P+ V L++
Sbjct: 2240 HDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDK 2299
Query: 429 RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
E+ R LEC+++ +RW K Q L G KY + +G +LII D D Y
Sbjct: 2300 IAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTY 2359
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWL 547
T D + ++A VEE+ T+ G+ DV +PA C WL
Sbjct: 2360 TC------DAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWL 2413
Query: 548 KDGKEITDLPG-MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDP 606
GK + G + + ++G VH+L+ G F + S A + ++D P +
Sbjct: 2414 L-GKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLT 2472
Query: 607 SVLEALAAHAITVKVGHTAHIKVPFRGKPLPK-VTWYKDGMEVTEEERVSMERGEDQALL 665
LE + V + FR P PK V WYKD ++ E+ M A L
Sbjct: 2473 RPLEPKTGRELQSVV-----LSCDFR--PAPKAVQWYKDDTPLSPSEKFKMSLEGQMAEL 2525
Query: 666 TISNCVREDSGLILLKLKNDHGSATATLHL-------SVLDRPKPPQGRVEF-LELSGSC 717
I + D+G+ + + H S T+ + D +G F ELS
Sbjct: 2526 RILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHED 2585
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI---KIGEVDGKVTNFSTNKVEEGKAYQF 774
++W NG E G++ + I D + S+ KV +
Sbjct: 2586 EEVEWSL---NGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEV 2642
Query: 775 RILAVNSEGVSDPLETEE 792
R+ V D L EE
Sbjct: 2643 RVKPVVFLKALDDLSAEE 2660
Score = 133 bits (335), Expect = 1e-30
Identities = 109/462 (23%), Positives = 188/462 (40%), Gaps = 23/462 (4%)
Query: 236 ILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYML 295
+ +PLE K + +VV C + + + W K PL K+ + G L
Sbjct: 2471 LTRPLEPKTGRELQSVVLSC--DFRPAPKAVQWYKDDTPLSPSE---KFKMSLEGQMAEL 2525
Query: 296 VISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKE 355
I + DAG+Y G S E+TV + G ++ + TE A F LS ++
Sbjct: 2526 RILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHED 2585
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTID 415
W NG L D +EI S G HTL +K + +D+G A + + A+L +
Sbjct: 2586 EEVEWSLNGMPLYNDSFHEI--SHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEVR 2643
Query: 416 RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAEL 475
P+ F+ L ++ +ER L+CE++ + + W+KDG L KY H L
Sbjct: 2644 VKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 476 IIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCV 535
++ D D G YT + + A V V + + + + G
Sbjct: 2704 VVHDVSPEDAGLYTCHVGSE------ETRARVRVHDLHVGITKRLKTMEVLEGESCSFEC 2757
Query: 536 VLNDEKVE--GVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESE 593
VL+ E +W GK + Q +QG + L+ P G+ F +G S+
Sbjct: 2758 VLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSK 2817
Query: 594 ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEER 653
AS+ + + P ++++ L + ++ G P V W KD + + ++
Sbjct: 2818 ASLIVRERPA---AIIKPLEDQWVAPGEDVELRCELSRAGTP---VHWLKDRKAIRKSQK 2871
Query: 654 VSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHL 695
+ A+L I +D+G ++ + +TA+LH+
Sbjct: 2872 YDVVCEGTMAMLVIRGASLKDAGEYTCEV--EASKSTASLHV 2911
Score = 133 bits (334), Expect = 1e-30
Identities = 153/631 (24%), Positives = 249/631 (39%), Gaps = 58/631 (9%)
Query: 70 VEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSI-NKEHVLKLE 128
+E + V EG A FR R+ + W + P+ + D+ HVL L
Sbjct: 3008 IEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDK-TPLHANELNEIDAQPGGYHVLTLR 3066
Query: 129 PLTSDDSDNYKCIASNDHADAIYTVS------------LLVTEGQE--------KMDFKK 168
L DS A + A A V+ +TEG++ D
Sbjct: 3067 QLALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPV 3126
Query: 169 MLKKRAPPAPKKKQKKVANEKEMLEIL-SKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKK 227
K + ++++E ++L + +D + E G ++R
Sbjct: 3127 CWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVR------- 3179
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
V +R + L+D E C++ VK W G LR KY ++
Sbjct: 3180 -VHARPVRFQEALKDLEVLEGGAATLRCVLSSVAAPVK--WCYGNNVLRPG---DKYSLR 3233
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
Q G LV+ N+ D+G YS S GD+ SA LTV P +F+G+++ + TE TA
Sbjct: 3234 QEGAMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATL 3293
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
LSK P W+ + L+ D+Y + +DG L+I+ + D+ E+S G
Sbjct: 3294 RCELSKAAP-VEWRKGSETLRDGDRY--CLRQDGAMCELQIRGLAMVDAAEYSCVCGEER 3350
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A LTI +P F+ L++ E + A L CEL SK + W+K + L G ++S+
Sbjct: 3351 TSASLTIRPMPAHFIGRLRHQESIEGATATLRCEL-SKAAPVEWRKGRESLRDGDRHSLR 3409
Query: 468 HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT 527
+G EL I ++D GEY+ V E ++A +TV+ A G+ + A
Sbjct: 3410 QDGAVCELQICGLAVADAGEYSCVC------GEERTSATLTVKALPAKFTEGLRNEEAVE 3463
Query: 528 GSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
G+ A L C + VE W K + + D + ++G +L + G+Y
Sbjct: 3464 GATAMLWCELSKVAPVE--WRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCV 3521
Query: 587 AKGTESEASVFI-ADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+ A++ I A P V A T + + P V W K
Sbjct: 3522 CGQERTSATLTIRALPARFIEDVKNQEAREGATAVLQCELNSAAP--------VEWRKGS 3573
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ + +R S+ + + L I D+G
Sbjct: 3574 ETLRDGDRYSLRQDGTKCELQIRGLAMADTG 3604
Score = 124 bits (311), Expect = 6e-28
Identities = 96/357 (26%), Positives = 153/357 (42%), Gaps = 13/357 (3%)
Query: 229 VEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQ 288
VE +A + L + + + T VF C E P + W KG LR GK+ Q
Sbjct: 2911 VEEKANCFTEELTNLQVEEKGTAVFTCKTE--HPAATVTWRKGLLELRAS---GKHQPSQ 2965
Query: 289 MGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFE 348
G L IS + D+ Y+ +G + A+L V + + +++ V V E +A F
Sbjct: 2966 EGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFR 3025
Query: 349 IRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
R+S V W + L ++ EI G H L ++ L DSG EAG+
Sbjct: 3026 CRISPANYEPVHWFLDKTPLHANELNEIDAQPGGY-HVLTLRQLALKDSGTIYFEAGDQR 3084
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A L + P F L + + E L CE ++ D+ + W KDG+ L + ++
Sbjct: 3085 ASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLS 3144
Query: 468 HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT 527
HEG RA+L+I A L D G Y A S++IV V R + + D+
Sbjct: 3145 HEGHRAQLLITGATLQDSGRYKCEA------GGACSSSIVRVHARPVRFQEALKDLEVLE 3198
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
G A L VL+ W + + ++GA+ +L+ ++ P+ G+Y+
Sbjct: 3199 GGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255
Score = 123 bits (309), Expect = 1e-27
Identities = 141/665 (21%), Positives = 252/665 (37%), Gaps = 80/665 (12%)
Query: 78 APEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDN 137
A G A V A+ ++W ++ G + S+K+ ++ L ++ D+
Sbjct: 902 AEAGASATLSCEV-AQAQTEVTWYKD-GKKLSSSSKVCMEATGCTRRLVVQQAGQADAGE 959
Query: 138 YKCIASNDH---------------------------ADAIYTVSLLVTEGQEKMDFKKML 170
Y C A A A T+S V + Q ++ + K
Sbjct: 960 YSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYKDG 1019
Query: 171 KKRAPPAPKKKQKKVANEKEMLEILSKVPKKDF------EKVCMEYGFTDFRGLLRKLKE 224
KK + + K + +++ K D+ ++V T+ + + K +
Sbjct: 1020 KKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQS 1079
Query: 225 MKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKY 284
+ +V+ EA + + C E+ ++ W K + L S K
Sbjct: 1080 VHNEVQAEA--------------GASAMLSC--EVAQAQTEVTWYKDGKKLS---SSSKV 1120
Query: 285 DVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMK---PVKVTE 341
++ G LV+ DAG YS G +R+S L + + F E V+
Sbjct: 1121 GMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEA 1180
Query: 342 RQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSA 401
TA+ +++ + W +GK+L K + V G T L ++ +D+GE+S
Sbjct: 1181 GTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVK--GCTRRLVVQQVGKADAGEYSC 1238
Query: 402 EAGNLVQKAQLTIDRIPIKFVSNL---KNVRVKERSRACLECELTSKDVTLRWKKDGQLL 458
EAG QL I F VR + + A L CE+ + W KDG+ L
Sbjct: 1239 EAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKL 1298
Query: 459 MHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYY----STAIVTVEERLA 514
+K + G +L+++ A +D GEYT A G ++ V +E+LA
Sbjct: 1299 SSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA--GGQRLSFHLDVSEPKAVFAKEQLA 1356
Query: 515 TVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPS 574
K V A G+ A L + + E W KDGK+++ +++ G +L+
Sbjct: 1357 HRK-----VQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQ 1411
Query: 575 MGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGK 634
G+Y+ A G S+ +A+P + E + + G + + +
Sbjct: 1412 ACQADTGEYSCEAGGQRLSFSLDVAEPKVV--FAKEQPVHREVQAQAGASTTLSCEV-AQ 1468
Query: 635 PLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLH 694
+V WYKDG +++ +V ME L + + +G + + GS + H
Sbjct: 1469 AQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAG----EYSCEAGSQRLSFH 1524
Query: 695 LSVLD 699
L V +
Sbjct: 1525 LHVAE 1529
Score = 123 bits (308), Expect = 1e-27
Identities = 102/455 (22%), Positives = 184/455 (40%), Gaps = 18/455 (3%)
Query: 230 EVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQM 289
E +A+ + L ++ + + + E+ ++ W K + L S K ++ +
Sbjct: 1345 EPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLS---SSSKVRMEAV 1401
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEM---KPVKVTERQTAV 346
G LV+ D G YS G +R+S L V + + F E + V+ +
Sbjct: 1402 GCTRRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTT 1461
Query: 347 FEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+++ + +W +GK+L K + + G T L ++ A + +GE+S EAG+
Sbjct: 1462 LSCEVAQAQTEVMWYKDGKKLSFSSK--VRMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQ 1519
Query: 407 VQKAQLTIDRIPIKFVSNL---KNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTK 463
L + F + V+ + + A L CE+ + W KDG+ L +K
Sbjct: 1520 RLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSK 1579
Query: 464 YSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
M G L++++A +D GEY+ A GD + + + A + +V
Sbjct: 1580 VRMEAVGCTRRLVVQEAGQADAGEYSCKA---GDQRLSFHLHVAEPKVVFAKEQPAHREV 1636
Query: 524 HAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKY 583
A G+ A L + + E W KDGK+++ +++ G +L+ G G+Y
Sbjct: 1637 QAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEY 1696
Query: 584 TFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKP-LPKVTWY 642
+ A G + +A+ ++P + E V H I P VTW
Sbjct: 1697 SCEAGGQRLSFRLHVAE---LEPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWL 1753
Query: 643 KDGMEVTEEERVSMERGEDQALLTISNCVREDSGL 677
KDG+E+ +R D LT+ DS +
Sbjct: 1754 KDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAI 1788
Score = 119 bits (299), Expect = 1e-26
Identities = 110/448 (24%), Positives = 187/448 (41%), Gaps = 32/448 (7%)
Query: 258 ELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRM 317
E+ ++ W K + L S K V+ +G LV+ DAG YS G +R+
Sbjct: 1649 EVAQAQTEVTWYKDGKKLS---SSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRL 1705
Query: 318 SAELTVLD-EPLKFLGEM----KPVKVTERQTAVFEIRLSKKEPNFV-WKFNGKELKRDD 371
S L V + EP + E +P+ V E + + L+ V W +G E++R
Sbjct: 1706 SFRLHVAELEPQ--ISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSK 1763
Query: 372 KYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVK 431
++E + G THTL + A++ DS +S G Q + ++ + KF L+ V +
Sbjct: 1764 RHE--TASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGE 1821
Query: 432 ERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVV 491
L CEL+ + W+ L G ++ M EG L + + D GEY
Sbjct: 1822 LGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCE 1881
Query: 492 AMQDGDPTEYYSTAIVTVE-ERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDG 550
+ D +++A +TV R+ SG+S V A G A V++ V VW +DG
Sbjct: 1882 SRDD------HTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVVWFRDG 1935
Query: 551 KEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLE 610
+ I + GA H L + E G+ T A+G S A++ + + P + LE
Sbjct: 1936 ALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKLE 1995
Query: 611 ALAAH---AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
++T++V T +P P++ W ++ + + V + + L +
Sbjct: 1996 PQTVEERSSVTLEVELT---------RPWPELRWTRNATALAPGKNVEIHAEGARHRLVL 2046
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHL 695
N D G + +D A T+ +
Sbjct: 2047 HNVGFADRGFFGCETPDDKTQAKLTVEM 2074
Score = 119 bits (298), Expect = 2e-26
Identities = 169/717 (23%), Positives = 269/717 (37%), Gaps = 69/717 (9%)
Query: 229 VEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQ 288
V +R L+ L+ +E T C EL + W KG+ L + KY + Q
Sbjct: 3974 VTAAPVRFLRELQHQEVDEGGTAHLCC--ELSRAGASVEWRKGSLQL---FPCAKYQMVQ 4028
Query: 289 MGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFE 348
G L++ V DAG Y+ G + A L+V KF ++ ++ A
Sbjct: 4029 DGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLC 4088
Query: 349 IRLSKKEPNFV--WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+LS E V W G EL KYE+ G T L I D+GE++ G
Sbjct: 4089 CQLSDAESGAVVQWLKEGVELHAGPKYEMR--SQGATRELLIHQLEAKDTGEYACVTGGQ 4146
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVT-LRWKKDGQLLMHGTKYS 465
A L + + V L + V CE++ T ++W G L
Sbjct: 4147 KTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTE 4206
Query: 466 MN-HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524
+ +G+ L ++ D G V+ G+ + S+A +TV T+ + DV
Sbjct: 4207 VAVRDGRIHTLRLKGVTPEDAG---TVSFHLGN---HASSAQLTVRAPEVTILEPLQDVQ 4260
Query: 525 AATGSPAEL-CVVLNDEKVEGVWLKDG-----KEITDLPGMQIVKQGAVHKLIFPSMGPE 578
+ G A C + E W G E+ D+ V+QG +H L + E
Sbjct: 4261 LSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDIT----VEQGTLHLLTLHKVTLE 4316
Query: 579 HEGKYTFRAKGTESEASVFIADPPTIDPSV--LEALAAHAITVKVGHTAHIKVPFRGKPL 636
G +F SEA + + T+ + +EAL G A + +
Sbjct: 4317 DAGTVSFHVGTCSSEAQLKVTAKNTVVRGLENVEALE--------GGEALFECQLSQPEV 4368
Query: 637 PKVTWYKDGMEVTEEERVSMERGED--QALLTISNCVREDSGLILLKLKNDHGSATATLH 694
TW D V E + E+ + LL + N +DS + + SA T+
Sbjct: 4369 AAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFLTVR 4428
Query: 695 LSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSW------ 748
R+E LE +K A + T + E VG+ SW
Sbjct: 4429 ----------GWRLEILE------PLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAA 4472
Query: 749 IKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQP 808
++ + D VT ++ ++ Q + D + + + +PP A
Sbjct: 4473 VQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASARLTVLGLPDPPEDA--- 4529
Query: 809 QVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
+V + VT++W AP DGG + GY VE ++ + W + + + G +C VDGL
Sbjct: 4530 EVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQW-RLCHELVPGPECVVDGLAP 4588
Query: 869 DTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKP----PGLVQDLHVSDSSNSSISL 921
Y FRV AV G G+P +V +P KP P + V+ + S+ L
Sbjct: 4589 GETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSLEL 4645
Score = 115 bits (289), Expect = 2e-25
Identities = 150/682 (21%), Positives = 262/682 (38%), Gaps = 59/682 (8%)
Query: 40 VRRKSSSIVEFFSL-VTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHI 98
++R + IV SL V+ S+ + F++ ++A E + V + + H+
Sbjct: 2619 IQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS-DPEAHV 2677
Query: 99 SWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTV----- 153
W+++ G+ + S K + L + ++ +D+ Y C ++ A V
Sbjct: 2678 VWRKD-GVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHV 2736
Query: 154 -------SLLVTEGQEKMDFKKMLKKRAPPAP-------------KKKQKKVANEKEMLE 193
++ V EG E F+ +L + P + Q K +L
Sbjct: 2737 GITKRLKTMEVLEG-ESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILV 2795
Query: 194 ILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVF 253
+ P E V G T L+ V I+KPLED+ V
Sbjct: 2796 VREAAPSDAGEVVFSVRGLTSKASLI---------VRERPAAIIKPLEDQWVAPGEDVEL 2846
Query: 254 DCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVG 313
C EL + W+K + +R KYDV GT MLVI ++ DAG Y+ V
Sbjct: 2847 RC--ELSRAGTPVHWLKDRKAIRKSQ---KYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901
Query: 314 DKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKY 373
+ +A L V ++ F E+ ++V E+ TAVF + W+ EL+ K+
Sbjct: 2902 ASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKH 2961
Query: 374 EITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKER 433
+ S++GLT L I +DS ++ + G +AQL + + + +L++V V+E
Sbjct: 2962 Q--PSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEG 3019
Query: 434 SRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHE-GKRAELIIEDAQLSDGGEYTVV 491
S A C ++ + + W D L ++ + G L + L D G +
Sbjct: 3020 SSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG---TI 3076
Query: 492 AMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGK 551
+ GD ++A + V E+ + ++D G L + + W KDGK
Sbjct: 3077 YFEAGDQR---ASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGK 3133
Query: 552 EITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEA 611
+ Q+ +G +L+ + G+Y A G S + V + P L+
Sbjct: 3134 TLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD 3193
Query: 612 LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCV 671
L V G A ++ P V W + ++ S+ + L + N
Sbjct: 3194 L-----EVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLR 3247
Query: 672 REDSGLILLKLKNDHGSATATL 693
+DSG + SAT T+
Sbjct: 3248 PQDSGRYSCSFGDQTTSATLTV 3269
Score = 115 bits (287), Expect = 4e-25
Identities = 137/583 (23%), Positives = 228/583 (39%), Gaps = 70/583 (12%)
Query: 261 DPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDK- 315
+P ++ W K +P+ ++ + Q G Y L I ++ + D+G Y ++G+
Sbjct: 36 NPTPQVSWEKDQQPVAAG---ARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAF 92
Query: 316 -----RMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLS-KKEPNFVWKFNGKELKR 369
++ AE ++ FL ++V E A F R+ P W +G+ L
Sbjct: 93 AAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGE 152
Query: 370 DDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQ----LTIDRIPIKFVSN- 424
D + V E G L+I+ AR D G + A N + A L +D S
Sbjct: 153 PDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRP 212
Query: 425 -------------------------------LKNVRVKERSRACLECELTS--KDVTLRW 451
+ V E A L C +T K T+ W
Sbjct: 213 GTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETV-W 271
Query: 452 KKDGQLLMHGTKYSMNHEGKRAELI-IEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVE 510
KKDGQL+ G ++ + + + ++ I + SD G YT A T YS+ +V V
Sbjct: 272 KKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT--YSSVLVVVR 329
Query: 511 ERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKL 570
E K + D+ A + E W K+ + I ++G +L
Sbjct: 330 EPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRL 389
Query: 571 IFPSMGPEHEGKYTFRA-KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKV 629
++ + + Y +G+ + A + + ++L L V+VG TA V
Sbjct: 390 TVRNVSADDDAVYICETPEGSRTVAEL------AVQGNLLRKLPRKT-AVRVGDTAMFCV 442
Query: 630 PFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA 689
P+ V W ++ EV RV++ + LTIS C ED G + + S
Sbjct: 443 EL-AVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTST 501
Query: 690 TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT--QFIVERRAVGKKS 747
+ +PP V + S + + W +P +G RPVT ++VE++ +G +
Sbjct: 502 QFCVSAPRKPPLQPPVDPVVKARMESSVI-LSW-SPPPHGERPVTIDGYLVEKKKLGTYT 559
Query: 748 WIKIGEVDGKVT-NFSTNKVEEGKAYQFRILAVNSEGVSDPLE 789
WI+ E + T + V E +QFR+ A+NS G S LE
Sbjct: 560 WIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLE 602
Score = 110 bits (275), Expect = 9e-24
Identities = 103/451 (22%), Positives = 183/451 (40%), Gaps = 23/451 (5%)
Query: 256 IMELKDPNVKMIWIKGTEPLRIQYSLG-KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGD 314
+ EL D + W+K L S G KY+V+ + +L++ +V +DAG+Y
Sbjct: 727 LAELSDQAAAVTWLKDGRTL----SPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG 782
Query: 315 KRMSAELTVLDEPLKFLGEMKP--VKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDK 372
R++ +L+V +M V A FE S+ + W +G EL
Sbjct: 783 GRIAYQLSVQGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSG- 841
Query: 373 YEITVSED-GLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNL---KNV 428
E + ED G H L D G +S G +L + + F + +
Sbjct: 842 -ERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKL 900
Query: 429 RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
+ + + A L CE+ + W KDG+ L +K M G L+++ A +D GEY
Sbjct: 901 QAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY 960
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLK 548
+ A G + + + A + S+V A G+ A L + + E +W K
Sbjct: 961 SCEA---GGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYK 1017
Query: 549 DGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSV 608
DGK+++ + + +G +L+ G G Y+ A+G + I +P +
Sbjct: 1018 DGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMM--FA 1075
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
E + + + G +A + + +VTWYKDG +++ +V ME L +
Sbjct: 1076 KEQSVHNEVQAEAGASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLP 1134
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLD 699
+ D+G + + G + HL + +
Sbjct: 1135 QAGKADAG----EYSCEAGGQRVSFHLHITE 1161
Score = 107 bits (267), Expect = 8e-23
Identities = 108/475 (22%), Positives = 186/475 (39%), Gaps = 34/475 (7%)
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
+V+ + +++PL DK V +C + V+ W KG++ L+ KY++
Sbjct: 2284 RVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVR--WFKGSQELQPG---PKYELV 2338
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G L+IS+V+ D Y+ GD + SA+ V ++ + + ++ V V E A F
Sbjct: 2339 SDGLYRKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWF 2398
Query: 348 EIRL---SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAG 404
E S + P W L+ + + ++G H L ++ + +G G
Sbjct: 2399 ECETSIPSVRPPK--WLLGKTVLQAGG--NVGLEQEGTVHRLMLRRTCSTMTGPVHFTVG 2454
Query: 405 NLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKY 464
A+L + IP+ L+ +E L C+ ++W KD L K+
Sbjct: 2455 KSRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKF 2514
Query: 465 SMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524
M+ EG+ AEL I +D G Y A TE VTVE R TV + D
Sbjct: 2515 KMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTE------VTVEAREVTVTGPLQDAE 2568
Query: 525 AATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
A A L+ E E W +G + + +I +G H L+ S+ G
Sbjct: 2569 ATEEGWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVR 2628
Query: 585 FRAKGTESEASVFIADPPTIDPSVLEALAAH-----AITVKVGHTAHIKVPFRGKPLPKV 639
+ + A + + P + L+ L+A A+ +V P V
Sbjct: 2629 ASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEV-----------SDPEAHV 2677
Query: 640 TWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLH 694
W KDG+++ ++ L + + ED+GL + ++ A +H
Sbjct: 2678 VWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVH 2732
Score = 97.8 bits (242), Expect = 6e-20
Identities = 187/849 (22%), Positives = 324/849 (38%), Gaps = 153/849 (18%)
Query: 329 KFLGEMKPVKVTERQTAVFEIRL-SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLK 387
+FL K V+ + A ++ P W+ + + + ++ + ++DG + L
Sbjct: 11 RFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRL--AQDGDLYRLT 68
Query: 388 IKDARLSDSGEFSAEAGNLVQKAQLTI-----------DRIPIKFVSNLKNVRVKERSRA 436
I D L DSG++ A N + +A + ++ P F+ ++RV+E S A
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAP-HFLLRPTSIRVREGSEA 127
Query: 437 CLECEL-TSKDVTLRWKKDGQLL--MHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVA- 492
C + S + W KDG+ L G + + G+ + L I A+ DGG Y V A
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 493 ------------MQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAE-------- 532
+ D D + S + LA ++ + A G+PA
Sbjct: 188 NPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQR-RREAMRAEGAPASPPSTGTRT 246
Query: 533 -----------LCVVLNDEKVEGVWLKDGKEITDLPGMQIV-----KQGAVHKLIFPSMG 576
C V + K E VW KDG+ +T+ G + V ++ V K++F
Sbjct: 247 CTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTE--GRRHVVYEDAQENFVLKILFCKQ- 303
Query: 577 PEHEGKYTFRAKG----TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFR 632
G YT A T S V + +P L+ L + K T +VP
Sbjct: 304 -SDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDL---EVREKESATFLCEVP-- 357
Query: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
+P + W+K+ + + +E + LT+ N +D + + + GS T
Sbjct: 358 -QPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYI--CETPEGSRT-- 412
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGR--PVTQFIVERRA-VGKKSWI 749
V L + G+ + K P+ R F VE VG W+
Sbjct: 413 ---------------VAELAVQGNLLR---KLPRKTAVRVGDTAMFCVELAVPVGPVHWL 454
Query: 750 KIGE---VDGKVTNFSTNKVEEGKAYQFRILAVNSEGV-------SDPLETEEVFAGNPI 799
+ E G+V + EG + I E V D + + P
Sbjct: 455 RNQEEVVAGGRVAISA-----EGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPR 509
Query: 800 EPPGFASQPQVTDVTK----EAVTITWNAPTQDGGAPVL--GYIVERRKKGSNLWVPVNK 853
+PP QP V V K +V ++W+ P G PV GY+VE++K G+ W+ ++
Sbjct: 510 KPP---LQPPVDPVVKARMESSVILSWSPPPH-GERPVTIDGYLVEKKKLGTYTWIRCHE 565
Query: 854 -DPIQGTKCTVDGLLEDTEYEFRVIAVNKAG-------PGQPSVPSSSVVAKDPVKPPGL 905
+ + + TV + E+ ++FRV A+N G PG + + + + P+K
Sbjct: 566 AEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHL-APKLAVRTPLKAVQA 624
Query: 906 VQDLHVSDSSNSSISLAWREPAEGDP-PSGYILEMRAEDTKEWSKCTKIPISGTCYTVGG 964
V+ V+ S + +++ A +G + + E+ + T+ ++P S
Sbjct: 625 VEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPAS-------- 676
Query: 965 LIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCI 1024
+ + F + E+ + V G+ A PPAA ++ ARL H + L
Sbjct: 677 -LHGAQLKFVANGI-ESSIRMEVRAAPGLTANKPPAAAAREVLARL--HEEAQLLAELSD 732
Query: 1025 HAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG 1082
AA V W KDG + + + S L+ R D+G+Y + + G
Sbjct: 733 QAA-------AVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG--G 783
Query: 1083 EARYDIHVR 1091
Y + V+
Sbjct: 784 RIAYQLSVQ 792
Score = 87.8 bits (216), Expect = 6e-17
Identities = 89/375 (23%), Positives = 153/375 (40%), Gaps = 29/375 (7%)
Query: 334 MKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARL 393
+K V+ E F + L+ W +G+ LK YEI D HTL I++
Sbjct: 619 LKAVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSVYEIHC--DRTRHTLTIREVPA 675
Query: 394 SDSGEFSAEAGNLVQKA---------QLTIDRIPIKFVSNLKNVRVKERSRACLECELTS 444
S G N ++ + LT ++ P + + V + A L EL+
Sbjct: 676 SLHGAQLKFVANGIESSIRMEVRAAPGLTANKPP---AAAAREVLARLHEEAQLLAELSD 732
Query: 445 KDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYST 504
+ + W KDG+ L G KY + R L++ D D G Y V+ Y
Sbjct: 733 QAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSR---GGRIAYQL 789
Query: 505 AIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQ 564
++ + L +G S V A G PA+ ++ V W KDG E+ G + +++
Sbjct: 790 SVQGLARFLHKDMAG-SCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGH-SGERFLQE 847
Query: 565 --GAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVG 622
G H+L+ ++ + EG Y+ R + + +++P + E LA + + G
Sbjct: 848 DVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVV--FAKEQLARRKLQAEAG 905
Query: 623 HTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKL 682
+A + + +VTWYKDG +++ +V ME L + + D+G +
Sbjct: 906 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAG----EY 960
Query: 683 KNDHGSATATLHLSV 697
+ G + HL V
Sbjct: 961 SCEAGGQRLSFHLDV 975
Score = 82.4 bits (202), Expect = 3e-15
Identities = 136/661 (20%), Positives = 232/661 (35%), Gaps = 85/661 (12%)
Query: 77 TAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSD 136
T EG A V G KP WK++ + + + Y+ + VLK+ D
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRG 307
Query: 137 NYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANEKEMLEILS 196
Y C ASN GQ ++++ A P K+ Q EKE L
Sbjct: 308 LYTCTASN-------------LVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLC 354
Query: 197 KVPKKDFEK----------VCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKET- 245
+VP+ E +YG + G R+L + +A+ I + E T
Sbjct: 355 EVPQPSTEAAWFKEETRLWASAKYGIEE-EGTERRLTVRNVSADDDAVYICETPEGSRTV 413
Query: 246 -------------------KVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDV 286
+V T +F C+ EL P + W++ E + + G+ +
Sbjct: 414 AELAVQGNLLRKLPRKTAVRVGDTAMF-CV-ELAVPVGPVHWLRNQEEV---VAGGRVAI 468
Query: 287 KQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTV-------LDEPL----------K 329
GT++ L IS + D G + GD + S + V L P+
Sbjct: 469 SAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESS 528
Query: 330 FLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIK 389
+ P ER + + KK+ E + E+TV++ + +
Sbjct: 529 VILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFR 588
Query: 390 DARLSDSGEFS-AEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVT 448
+ L+ G+ E V A R P LK V+ E +LT
Sbjct: 589 VSALNSFGQSPYLEFPGTVHLAPKLAVRTP------LKAVQAVEGGEVTFSVDLTVASAG 642
Query: 449 LRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGG---EYTVVAMQDGDPTEYYSTA 505
W DGQ L + Y ++ + R L I + S G ++ ++ E +
Sbjct: 643 -EWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAP 701
Query: 506 IVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQG 565
+T + A + +V A A+L L+D+ WLKDG+ ++ P ++
Sbjct: 702 GLTANKPPA---AAAREVLARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASA 758
Query: 566 AVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTA 625
L+ + + G Y ++G + + + + + +A + G A
Sbjct: 759 GRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQG---LARFLHKDMAGSCVDAVAGGPA 815
Query: 626 HIKVPFRGKPLPKVTWYKDGMEVTEE-ERVSMERGEDQALLTISNCVREDSGLILLKLKN 684
+ + V WYKDGME+ ER E + L + R+D G ++
Sbjct: 816 QFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGE 874
Query: 685 D 685
D
Sbjct: 875 D 875
Score = 66.6 bits (161), Expect = 1e-10
Identities = 67/272 (24%), Positives = 101/272 (37%), Gaps = 25/272 (9%)
Query: 1016 VRAGTALCIHAAFSGSPPP-DVIWQKDGV---PTKGRETITKSKNHSQFLINSTKRSDSG 1071
VRAG C S + P + W +G P T+T +H L+ S + +G
Sbjct: 4443 VRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAG 4502
Query: 1072 VYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYI 1131
++ AR + V P PP + + +TVTL+W G Y
Sbjct: 4503 EVTFACRDAVASAR----LTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYR 4558
Query: 1132 IMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINK 1191
+ ++ +T W E V + V GL PG Y FRV A +G EP ++
Sbjct: 4559 VEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEP--------VHL 4610
Query: 1192 DQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDV 1251
Q L+ KP P + + V G+D ++ + V +KG
Sbjct: 4611 PQTVRLAEPPKP--------VPPQPSAPESRQVAAGEDVSLELEVVAE-AGEVIWHKGME 4661
Query: 1252 NITANSKFWYNSTSGVCTLVIPTCTLKDSGDY 1283
I +F S LVI T +D G+Y
Sbjct: 4662 RIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693
Score = 60.8 bits (146), Expect = 8e-09
Identities = 103/449 (22%), Positives = 178/449 (39%), Gaps = 103/449 (22%)
Query: 412 LTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEG 470
LT D P+ F++ L+N V++ +C +T + + ++RW KDG+LL Y +N +
Sbjct: 5120 LTSDAAPV-FLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178
Query: 471 KRA-ELIIEDAQLSDGGEYTVVAMQD----------------------GDPTE---YYS- 503
+ +LII +D G Y +A D TE Y+S
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238
Query: 504 -----------TAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGV------W 546
T T E +L V + D+ A G+ + KV+G W
Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQL----KVKGYPAPRLYW 5294
Query: 547 LKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF---RAKGTE-SEASVFIADPP 602
KDG+ +T +++ + +H L S+ E G+Y A G S A + + P
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD 5354
Query: 603 T-------------IDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVT 649
+ P +LE VK G + V G+P+P V W ++
Sbjct: 5355 EPEEKPASDVHEQLVPPRMLERFTPKK--VKKGSSITFSVKVEGRPVPTVHWLRE----- 5407
Query: 650 EEERVSMERGEDQALLTISNCVREDSGLILLKLKNDH------------GSA--TATLHL 695
E ER + G D T+++ ++ S L+LL + H G A +A+LH+
Sbjct: 5408 EAERGVLWIGPDTPGYTVASSAQQHS-LVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466
Query: 696 SVLDRPKPPQGRVEFL---ELSG-----SCVHMKWKAPKDNGGRPVTQFIVERRAVGKKS 747
S L + + + E L L G S ++ + D GG+ + + + A+G S
Sbjct: 5467 SGLPKVEEQEKVKEALISTFLQGTTQAISAQGLETASFADLGGQRKEEPLAAKEALGHLS 5526
Query: 748 WIKIG------EVDGKVTNFSTNKVEEGK 770
++G ++ ++T + K+ + K
Sbjct: 5527 LAEVGTEEFLQKLTSQITEMVSAKITQAK 5555
Score = 60.1 bits (144), Expect = 1e-08
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 903 PGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCY 960
P +D V S+ +++L+W P G GY +E++ T +W C ++ C
Sbjct: 4523 PDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPEC- 4581
Query: 961 TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGT 1020
V GL + Y FR+ AV G GEPV L + VR PP SA +
Sbjct: 4582 VVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDV 4641
Query: 1021 ALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
+L + +VIW K + + GR + +I D G Y
Sbjct: 4642 SLELEVVAEAG---EVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693
Score = 53.1 bits (126), Expect = 2e-06
Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNS--TSGVCTL 1270
PRFV ++ + G+D TC G P P + YK +T +KF S SG+ L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
VI + +D G Y + N LG R+S L +
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/91 (32%), Positives = 44/91 (48%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLV 1271
APRF+T K V G+D T++C +GNP P V+ K + A ++F + L
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLT 68
Query: 1272 IPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
I L DSG Y N +G+ ++ L V
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 48.1 bits (113), Expect = 5e-05
Identities = 47/182 (25%), Positives = 68/182 (37%), Gaps = 6/182 (3%)
Query: 520 MSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQ-GAVHKLIFPSMGP 577
++D A G +L C V K W KDGK + P +++ LI S+
Sbjct: 6020 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 6079
Query: 578 EHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLP 637
G+Y A S + P + + A G A G P P
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVE--GEDAQFTCTIEGAPYP 6137
Query: 638 KVTWYKDGMEVTEEERVS--MERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHL 695
++ WYKDG +T + E +L I +ED GL +L N GSA A+ L
Sbjct: 6138 QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAEL 6197
Query: 696 SV 697
+
Sbjct: 6198 RI 6199
Score = 45.8 bits (107), Expect = 3e-04
Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 7/125 (5%)
Query: 38 EVVRRKSSSIVEFFSLVTRSSNIPAG--DSVPEFVEKPQPVTAPEGDKAVFRARVQGNAK 95
+ V R ++I E F+ V + A + P F+ +P + EG +A FR RV G+ +
Sbjct: 79 QYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPR 138
Query: 96 PHISWKRES---GIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYT 152
P +SW ++ G P + ++ + + + L++ D Y+ A N A
Sbjct: 139 PAVSWSKDGRRLGEP--DGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196
Query: 153 VSLLV 157
+L+V
Sbjct: 197 AALVV 201
Score = 44.7 bits (104), Expect = 6e-04
Identities = 61/263 (23%), Positives = 100/263 (38%), Gaps = 36/263 (13%)
Query: 1029 SGSPPPDVIWQKDG-VPTKGRETITKSKNHSQFLIN--STKRSDSGVYRILLQNEFGEAR 1085
+G P P+ +W+KDG + T+GR + F++ K+SD G+Y N G+
Sbjct: 262 TGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTY 321
Query: 1086 YDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDAST-ATWYT 1144
+ V V + P P RL +V+E A ++ ST A W+
Sbjct: 322 SSVLVVVRE-PAVPFKKRL-------------QDLEVREKESATFLCEVPQPSTEAAWFK 367
Query: 1145 AAERVF-SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203
R++ S KY + R R+ RN D + + ++ + A+L
Sbjct: 368 EETRLWASAKYGIEEEGTER----RLTVRNVSADDDAV-----YICETPEGSRTVAEL-A 417
Query: 1204 YEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNS 1263
+ R PR T +R D M C L P V + + A + ++
Sbjct: 418 VQGNLLRKLPR-------KTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISA 470
Query: 1264 TSGVCTLVIPTCTLKDSGDYSVL 1286
TL I C L+D G + +
Sbjct: 471 EGTRHTLTISQCCLEDVGQVAFM 493
Score = 42.0 bits (97), Expect = 0.004
Identities = 31/108 (28%), Positives = 42/108 (38%), Gaps = 2/108 (1%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN-STSGVCTL 1270
AP F+T L+ V G + C G P P+V +K + + + N G L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTV-YDKDDKSVVASITES 1317
+I D G Y L EN +G + L V D A TES
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATES 5232
Score = 41.6 bits (96), Expect = 0.005
Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 1/97 (1%)
Query: 61 PAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSIN 120
P P F+ +P+ G A ++ GN P +SW+++ P+ A+
Sbjct: 4 PQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQ-PVAAGARFRLAQDG 62
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV 157
+ L + L DS Y C A N +A V L V
Sbjct: 63 DLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 41.2 bits (95), Expect = 0.007
Identities = 71/302 (23%), Positives = 114/302 (37%), Gaps = 44/302 (14%)
Query: 438 LECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGK-RAELIIEDAQLSDGGEYTVVAMQD 495
LEC + SK DV RW KDG L G + ++ G L+I +D G YT
Sbjct: 4917 LECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNK 4976
Query: 496 GDPTEYYSTAIVTVEERLATVKSG--MSDVHAA----------TGSPAE-----LCVVLN 538
+ + +V+ E A SG + D T SPAE L + +
Sbjct: 4977 FGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSAD 5036
Query: 539 DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKL---------IFPSMGPEHEGKYTF---- 585
+ E D + + ++ A+ + +F ++G E K
Sbjct: 5037 EGPAEPEEPADWQTYREDEHFICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPR 5096
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKV-------GHTAHIKVPFRGKPLPK 638
R + S+ + PP PS+L + AA ++ G+ G+P+P
Sbjct: 5097 RVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPS 5156
Query: 639 VTWYKDGMEVTEEERVSMERGEDQA---LLTISNCVREDSGLILLKLKNDHGSATATLHL 695
V W+KDG + E++ + EDQ L I+ V D G+ +N G ++ L
Sbjct: 5157 VRWFKDGKLLEEDDHYMI--NEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAEL 5214
Query: 696 SV 697
V
Sbjct: 5215 RV 5216
Score = 40.4 bits (93), Expect = 0.011
Identities = 24/78 (30%), Positives = 35/78 (44%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P+F E+ TA G+ RV G KP ISW ++ + I + + L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 127 LEPLTSDDSDNYKCIASN 144
L+ LT DS Y C A++
Sbjct: 6074 LDSLTGVDSGQYMCFAAS 6091
Score = 39.3 bits (90), Expect = 0.025
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 13/127 (10%)
Query: 66 VPEFVEKPQPVTAPEGDK-AVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV 124
+P+ VE+ + + G + A F+ +V+G P + W ++ G P+ SA I H
Sbjct: 5259 LPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKD-GQPLTASAHIRMTDKKILHT 5317
Query: 125 LKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV-----------TEGQEKMDFKKMLKKR 173
L++ +T +DS Y SN A + LLV ++ E++ +ML++
Sbjct: 5318 LEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERF 5377
Query: 174 APPAPKK 180
P KK
Sbjct: 5378 TPKKVKK 5384
Score = 38.9 bits (89), Expect = 0.033
Identities = 36/141 (25%), Positives = 62/141 (43%), Gaps = 9/141 (6%)
Query: 355 EPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEF----SAEAGNLVQKA 410
+P W +GK ++ D + + DG + L + DSG++ ++ AGN
Sbjct: 6042 KPVISWYKDGKAVQVDPHHILIEDPDG-SCALILDSLTGVDSGQYMCFAASAAGNCSTLG 6100
Query: 411 QLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVT-LRWKKDGQLLMHGTKYSMNHE 469
++ + ++P +FV+ ++ E A C + +RW KDG LL G K+ E
Sbjct: 6101 KILV-QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 6159
Query: 470 GKRA--ELIIEDAQLSDGGEY 488
+ L+I A D G Y
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLY 6180
Score = 38.1 bits (87), Expect = 0.056
Identities = 68/325 (20%), Positives = 112/325 (34%), Gaps = 53/325 (16%)
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKG--RETITKSKNHSQFLINSTKRSDSGV 1072
VV G + G+P P V W+KD P R + + + + I DSG
Sbjct: 20 VVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQ 79
Query: 1073 YRILLQNEFGEARYDIHVRV----------ADFPRPPTNLRLFEEVPNTV---------- 1112
Y +N GEA + ++V F PT++R+ E T
Sbjct: 80 YVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRP 139
Query: 1113 TLTWNHS------PD-----VQEDGEAHYIIMK--RDASTATWYTAAERVFSNKYTVTGL 1159
++W+ PD V+E GEA + ++ R T+ AE L
Sbjct: 140 AVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAAL 199
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPL 1219
+ DS+ D+ + + + + + + A T
Sbjct: 200 ---------------VVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGT 244
Query: 1220 KPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSK--FWYNSTSGVCTLVIPTCTL 1277
+ TV G+ ++C G P+P T++K D + + Y L I C
Sbjct: 245 RTCTVTEGKHARLSCYVTGEPKPE-TVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ 303
Query: 1278 KDSGDYSVLVENELGKDRSSCTLTV 1302
D G Y+ N +G+ SS + V
Sbjct: 304 SDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 38.1 bits (87), Expect = 0.056
Identities = 98/500 (19%), Positives = 179/500 (35%), Gaps = 92/500 (18%)
Query: 64 DSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEH 123
D+ P F+ + Q +G F V G P + W ++ + ++ + + H
Sbjct: 5123 DAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182
Query: 124 VLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQK 183
L + + D Y+C+A N ++ + T+ + ++D A A +
Sbjct: 5183 QLIITAVVPADMGVYRCLAEN-------SMGVSSTKAELRVDLTSTDYDTAADATESSSY 5235
Query: 184 KVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDK 243
A LS ++ E TD E + ++++ L D
Sbjct: 5236 FSAQ-----GYLSSREQEGTEST------TD---------------EGQLPQVVEELRDL 5269
Query: 244 ETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMN 303
+ T + + P ++ W K +PL + D K + T L I +V
Sbjct: 5270 QVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHT---LEIISVTRE 5326
Query: 304 DAGIY----SLSVGDKRMSAELTVL--DE--------------PLKFLGEMKPVKVTERQ 343
D+G Y S ++G SA L V DE P + L P KV +
Sbjct: 5327 DSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGS 5386
Query: 344 TAVFEIRL-SKKEPNFVWKFNGKELKR------DDKYEITVSEDGLTHTLKIKDARLSDS 396
+ F +++ + P W +E +R D TV+ H+L + D
Sbjct: 5387 SITFSVKVEGRPVPTVHWL--REEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQ 5444
Query: 397 GEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQ 456
G ++ A N +A + VS L V +E+ + L
Sbjct: 5445 GTYTCIASNAAGQALCSAS----LHVSGLPKVEEQEKVKEALI----------------S 5484
Query: 457 LLMHGTKYSMNHEGKRAELIIEDAQLSD-GGEYTVVAMQDGDPTEYYSTAIVTVEERLAT 515
+ GT +++ +G +E A +D GG+ + + + S A V EE L
Sbjct: 5485 TFLQGTTQAISAQG------LETASFADLGGQRKEEPLAAKEALGHLSLAEVGTEEFLQK 5538
Query: 516 VKSGMSDVHAATGSPAELCV 535
+ S ++++ +A + A+L V
Sbjct: 5539 LTSQITEMVSAKITQAKLQV 5558
Score = 37.7 bits (86), Expect = 0.074
Identities = 39/172 (22%), Positives = 63/172 (36%), Gaps = 13/172 (7%)
Query: 1129 HYIIMK--RDASTATWYTAAERVFSNKYTVTGL-----LPGRKYYFRVVARNEIGDSEPL 1181
H +I K RD+ T T VF N ++ + + G F V E + L
Sbjct: 5928 HLVICKPRRDSRTDT----VSYVFRNMMKLSSIDLNDQVEGDDRAFEVWQEREDSVRKYL 5983
Query: 1182 DSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPR 1241
T +I ++++ + WR P F L T G+ + C G P+
Sbjct: 5984 LQARTAIIKSSWVKEICGIQQRLALPVWR-PPDFEEELADCTAELGETVKLACRVTGTPK 6042
Query: 1242 PTVTLYKGDVNITAN-SKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELG 1292
P ++ YK + + G C L++ + T DSG Y + G
Sbjct: 6043 PVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAG 6094
Score = 37.4 bits (85), Expect = 0.096
Identities = 56/279 (20%), Positives = 102/279 (36%), Gaps = 42/279 (15%)
Query: 1032 PPPDVIWQKDGVPT--KGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR---Y 1086
P V+W+KDGV + + +++ D+G+Y + +E AR +
Sbjct: 2673 PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVH 2732
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA 1146
D+HV + L+ E + E ++ AS +T
Sbjct: 2733 DLHVGITK------RLKTMEVLEG-------------ESCSFECVLSHESASDPAMWTVG 2773
Query: 1147 ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEK 1206
+ + GRKY V ++ P D+ + ++ L++K +
Sbjct: 2774 GKTVGSSSRFQATRQGRKYILVV------REAAPSDAGEVVF----SVRGLTSKASLIVR 2823
Query: 1207 KDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG 1266
+ + PL+ V G+D + C L V K I + K+
Sbjct: 2824 E---RPAAIIKPLEDQWVAPGEDVELRCE-LSRAGTPVHWLKDRKAIRKSQKYDVVCEGT 2879
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+ LVI +LKD+G+Y+ VE +S+ +L V +K
Sbjct: 2880 MAMLVIRGASLKDAGEYTCEVE----ASKSTASLHVEEK 2914
Score = 37.4 bits (85), Expect = 0.096
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 1030 GSPPPDVIWQKDG-VPTKGRETITKSKNHSQFL---INSTKRSDSGVYRILLQNEFGEAR 1085
G+P P + W KDG + T G + T S+ S L I + + D G+Y L N G AR
Sbjct: 6133 GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSAR 6192
Query: 1086 YDIHVRV 1092
+R+
Sbjct: 6193 ASAELRI 6199
Score = 36.2 bits (82), Expect = 0.21
Identities = 33/134 (24%), Positives = 55/134 (41%), Gaps = 23/134 (17%)
Query: 982 GVGEPVEL-DKGVRAM--------PPPAAPKFDLSARLKS-----------HMVVRAGTA 1021
G+G ++L ++G R + P P P L + L S + V+ G
Sbjct: 5083 GIGVEIKLVEQGPRRVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYP 5142
Query: 1022 LCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHS---QFLINSTKRSDSGVYRILLQ 1078
+ +G P P V W KDG + + +++ Q +I + +D GVYR L +
Sbjct: 5143 VSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAE 5202
Query: 1079 NEFGEARYDIHVRV 1092
N G + +RV
Sbjct: 5203 NSMGVSSTKAELRV 5216
Score = 35.8 bits (81), Expect = 0.28
Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 11/107 (10%)
Query: 1215 FVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPT 1274
F+ L+ + G T+ C L P V KG ++ + VC L I
Sbjct: 3364 FIGRLRHQESIEGATATLRCE-LSKAAP-VEWRKGRESLRDGDRHSLRQDGAVCELQICG 3421
Query: 1275 CTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQKK 1321
+ D+G+YS + G++R+S TLTV K++ A TE L+ +
Sbjct: 3422 LAVADAGEYSCV----CGEERTSATLTV-----KALPAKFTEGLRNE 3459
Score = 35.4 bits (80), Expect = 0.37
Identities = 21/70 (30%), Positives = 33/70 (47%)
Query: 1238 GNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSS 1297
G P P + +K +TA++ + TL I + T +DSG Y+ + N +G SS
Sbjct: 5286 GYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSS 5345
Query: 1298 CTLTVYDKDD 1307
L V D+
Sbjct: 5346 ARLLVRGPDE 5355
Score = 35.0 bits (79), Expect = 0.48
Identities = 20/89 (22%), Positives = 38/89 (42%), Gaps = 7/89 (7%)
Query: 589 GTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEV 648
G + ++ + PP + + + T ++G T + G P P ++WYKDG V
Sbjct: 6001 GIQQRLALPVWRPPDFEEELADC------TAELGETVKLACRVTGTPKPVISWYKDGKAV 6054
Query: 649 -TEEERVSMERGEDQALLTISNCVREDSG 676
+ + +E + L + + DSG
Sbjct: 6055 QVDPHHILIEDPDGSCALILDSLTGVDSG 6083
Score = 34.3 bits (77), Expect = 0.82
Identities = 70/311 (22%), Positives = 117/311 (37%), Gaps = 43/311 (13%)
Query: 265 KMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVL 324
++IW KG E RIQ G+++V G + MLVI D G Y + A+ ++
Sbjct: 4653 EVIWHKGME--RIQPG-GRFEVVSQGRQQMLVIKGFTAEDQGEYHCGL------AQGSIC 4703
Query: 325 DEPLKFLGEMKPVKVTER-QTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLT 383
F + P V E Q ++ + + + +W+ + KR E T+ D ++
Sbjct: 4704 PAAATFQVALSPASVDEAPQPSLPPEAAQEGDLHLLWEALAR--KRRMSREPTL--DSIS 4759
Query: 384 HTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELT 443
L +D R + + E + + T D + ++L + + SRA
Sbjct: 4760 E-LPEEDGRSQRLPQEAEEVAPDLSEGYSTADELARTGDADLSHTSSDDESRA------G 4812
Query: 444 SKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQD------GD 497
+ + KK G+ GT + G A ++ Q + + D GD
Sbjct: 4813 TPSLVTYLKKAGR---PGTSPLASKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGD 4869
Query: 498 PTEYYSTAIVTVEERLATVKSGMS------------DVHAATGSPAEL-CVVLNDEKVEG 544
P+ + + + V+ M D A G L CVV + V
Sbjct: 4870 PSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRA 4929
Query: 545 VWLKDGKEITD 555
WLKDG E+TD
Sbjct: 4930 RWLKDGVELTD 4940
Score = 33.5 bits (75), Expect = 1.4
Identities = 23/105 (21%), Positives = 43/105 (40%), Gaps = 10/105 (9%)
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKD---------GVPTKGRETITKSKNHSQFLINSTK 1066
V+ G+++ G P P V W ++ G T G + ++ HS L++
Sbjct: 5382 VKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLD-VG 5440
Query: 1067 RSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNT 1111
R G Y + N G+A + V+ P+ ++ E + +T
Sbjct: 5441 RQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALIST 5485
Score = 32.3 bits (72), Expect = 3.1
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 1214 RFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIP 1273
RF+ +K G + C L P V KG + ++ C L I
Sbjct: 3803 RFIEDVKNQEAREGATAVLQCE-LSKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQIH 3860
Query: 1274 TCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
++ D+G+YS + G++R+S TLTV
Sbjct: 3861 GLSVADTGEYSCV----CGQERTSATLTV 3885
Score = 32.3 bits (72), Expect = 3.1
Identities = 25/72 (34%), Positives = 27/72 (37%), Gaps = 3/72 (4%)
Query: 1016 VRAGTALC-IHAAFSGSPPPDVIWQKDGVPTKGRETI--TKSKNHSQFLINSTKRSDSGV 1072
V GT L G P P + W KDG P I T K I S R DSG
Sbjct: 5271 VAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQ 5330
Query: 1073 YRILLQNEFGEA 1084
Y + N G A
Sbjct: 5331 YAAYISNAMGAA 5342
Score = 32.0 bits (71), Expect = 4.0
Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 620 KVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMER-GEDQALLTISNCVREDSGLI 678
+VG ++ K + W KDG+E+T+ +++ G+ L I+ R D+G
Sbjct: 4910 QVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCY 4969
Query: 679 LLKLKNDHGSAT 690
++ N G T
Sbjct: 4970 TCQVSNKFGQVT 4981
Score = 31.6 bits (70), Expect = 5.3
Identities = 25/108 (23%), Positives = 43/108 (39%), Gaps = 11/108 (10%)
Query: 1214 RFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIP 1273
RF+ +K G + C N V KG + ++ C L I
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIR 3596
Query: 1274 TCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQKK 1321
+ D+G+YS + G++R+S LTV +++ TE L+ +
Sbjct: 3597 GLAMADTGEYSCV----CGQERTSAMLTV-----RALPIKFTEGLRNE 3635
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 165 bits (417), Expect = 3e-40
Identities = 157/655 (23%), Positives = 275/655 (41%), Gaps = 65/655 (9%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKL 127
+F E + A EG AV R + A P WK + + + D E L++
Sbjct: 3627 KFTEGLRNEEATEGATAVLRCELSKMA-PVEWWKGHETLRDGDRHSLRQDGARCE--LQI 3683
Query: 128 EPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKM-----------LKKRAPP 176
L ++D+ Y C+ + A+ TV + ++ E + ++ L K AP
Sbjct: 3684 RGLVAEDAGEYLCMCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLWCELSKAAPV 3743
Query: 177 APKKKQKKVANEKE------------MLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKE 224
+K + + + + L+ V ++ VC + +
Sbjct: 3744 EWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQ-------------ER 3790
Query: 225 MKKKVEVEAI--RILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLG 282
+ V A+ R ++ ++++E + T V C + P + W KG+E LR
Sbjct: 3791 TSATLTVRALPARFIEDVKNQEAREGATAVLQCELSKAAP---VEWRKGSETLR---GGD 3844
Query: 283 KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTER 342
+Y ++Q GT+ L I +++ D G YS G +R SA LTV F ++ ++ E
Sbjct: 3845 RYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPVFREPLQSLQAEEG 3904
Query: 343 QTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAE 402
TA + LS+ VW G +L+ + + E + G T L ++D + D+GE++
Sbjct: 3905 STATLQCELSEPTATVVWSKGGLQLQANGRREPRLQ--GCTAELVLQDLQREDTGEYTCT 3962
Query: 403 AGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGT 462
G+ A LT+ P++F+ L++ V E A L CEL+ ++ W+K L
Sbjct: 3963 CGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGSLQLFPCA 4022
Query: 463 KYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSD 522
KY M +G AEL++ + D G+YT D S A ++V K+ +
Sbjct: 4023 KYQMVQDGAAAELLVRGVEQEDAGDYTC------DTGHTQSMASLSVRVPRPKFKTRLQS 4076
Query: 523 VHAATGSPAELCVVLNDEKVEGV--WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHE 580
+ TG A LC L+D + V WLK+G E+ P ++ QGA +L+ + +
Sbjct: 4077 LEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDT 4136
Query: 581 GKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVT 640
G+Y G ++ AS+ + +P + +++ L +T +V G V
Sbjct: 4137 GEYACVTGGQKTAASLRVTEP---EVTIVRGLVDAEVTADEDVEFSCEVSRAG--ATGVQ 4191
Query: 641 WYKDGMEVTEEE--RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL 693
W G+ + E V++ G L + ED+G + L N SA T+
Sbjct: 4192 WCLQGLPLQSNEVTEVAVRDGRIHT-LRLKGVTPEDAGTVSFHLGNHASSAQLTV 4245
Score = 152 bits (384), Expect = 2e-36
Identities = 124/464 (26%), Positives = 200/464 (43%), Gaps = 20/464 (4%)
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
+VE A + + LE ++ TV C EL +++W G LR+ ++ +
Sbjct: 1803 QVEEVAAKFCRLLEPVCGELGGTVTLAC--ELSPACAEVVWRCGNTQLRVGK---RFQMV 1857
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTV-LDEPLKFLGEMKPVKVTERQTAV 346
G L + + DAG Y D SA+LTV + +KF+ + V E A
Sbjct: 1858 AEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEAT 1917
Query: 347 FEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
F+ +S + VW +G L+ +K+ I S+ G +H+L I D L D+G+ + EA
Sbjct: 1918 FQCVVSPSDVAVVWFRDGALLQPSEKFAI--SQSGASHSLTISDLVLEDAGQITVEAEGA 1975
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM 466
A L + P+ F L+ V+ERS LE ELT LRW ++ L G +
Sbjct: 1976 SSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEI 2035
Query: 467 NHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAA 526
+ EG R L++ + +D G + D + A +TVE R + G+ V A
Sbjct: 2036 HAEGARHRLVLHNVGFADRGFFGCETPDD------KTQAKLTVEMRQVRLVRGLQAVEAR 2089
Query: 527 TGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
A + V L+ V+G W +DG P + +G +H L + PE G F+
Sbjct: 2090 EQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFK 2149
Query: 587 AKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGM 646
A+G + A + + + P S L T K T ++ +P V W KDG+
Sbjct: 2150 AEGVHTSARLVVTELPV---SFSRPLQDVVTTEKEKVTLECEL---SRPNVDVRWLKDGV 2203
Query: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSAT 690
E+ + +++ LTI C D G+ + + SA+
Sbjct: 2204 ELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSAS 2247
Score = 151 bits (382), Expect = 4e-36
Identities = 139/499 (27%), Positives = 221/499 (44%), Gaps = 35/499 (7%)
Query: 235 RILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYM 294
R ++ ++++E + T V C + P + W KG+E LR +Y ++Q GTK
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCELNSAAP---VEWRKGSETLR---DGDRYSLRQDGTKCE 3592
Query: 295 LVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKK 354
L I + M D G YS G +R SA LTV P+KF ++ + TE TAV LSK
Sbjct: 3593 LQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKM 3652
Query: 355 EPNFVWKFNGKELKRD-DKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLT 413
P WK G E RD D++ ++ +DG L+I+ D+GE+ G A LT
Sbjct: 3653 APVEWWK--GHETLRDGDRH--SLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLT 3708
Query: 414 IDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRA 473
+ +P KF+ L+N E A L CEL SK + W+K + L G ++S+ +G R
Sbjct: 3709 VRAMPSKFIEGLRNEEATEGDTATLWCEL-SKAAPVEWRKGHETLRDGDRHSLRQDGSRC 3767
Query: 474 ELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL 533
EL I + D GEY+ V Q+ ++A +TV A + + A G+ A L
Sbjct: 3768 ELQIRGLAVVDAGEYSCVCGQE------RTSATLTVRALPARFIEDVKNQEAREGATAVL 3821
Query: 534 -CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTES 592
C + VE W K + + + + G +L + G+Y+ +
Sbjct: 3822 QCELSKAAPVE--WRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERT 3879
Query: 593 EASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEE 652
A++ + P + L++L A + G TA ++ +P V W K G+++
Sbjct: 3880 SATLTVRAPQPVFREPLQSLQA-----EEGSTATLQCEL-SEPTATVVWSKGGLQLQANG 3933
Query: 653 RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATL------HLSVLDRPKPPQG 706
R A L + + RED+G + SAT T+ L L + +G
Sbjct: 3934 RREPRLQGCTAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEG 3993
Query: 707 RVEFL--ELSGSCVHMKWK 723
L ELS + ++W+
Sbjct: 3994 GTAHLCCELSRAGASVEWR 4012
Score = 137 bits (344), Expect = 9e-32
Identities = 179/798 (22%), Positives = 293/798 (36%), Gaps = 106/798 (13%)
Query: 66 VPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVL 125
V +F+ V A EG +A F+ V + + W R+ + ++ S K H L
Sbjct: 1898 VVKFMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDGAL-LQPSEKFAISQSGASHSL 1955
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKV 185
+ L +D+ A + A V + + KK+ P +++ V
Sbjct: 1956 TISDLVLEDAGQITVEAEGASSSAALRVR----------EAPVLFKKKLEPQTVEERSSV 2005
Query: 186 ANEKEMLE----------ILSKVPKKDFE---------KVCMEYGFTDFRGLLR-----K 221
E E+ + P K+ E V GF D RG
Sbjct: 2006 TLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFAD-RGFFGCETPDD 2064
Query: 222 LKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSL 281
+ K VE+ +R+++ L+ E + T + ++L +V W + + LR Q
Sbjct: 2065 KTQAKLTVEMRQVRLVRGLQAVEAREQGTATME--VQLSHADVDGSWTR--DGLRFQQGP 2120
Query: 282 GKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTE 341
+ + G + L +S + D+G+ SA L V + P+ F ++ V TE
Sbjct: 2121 TCH-LAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVVTTE 2179
Query: 342 RQTAVFEIRLSKKEPNFVWKFNGKELK--------------------------------- 368
++ E LS+ + W +G EL+
Sbjct: 2180 KEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDA 2239
Query: 369 RDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNV 428
D + +V G T+TL + D+GE A N +AQL + +P+ V L++
Sbjct: 2240 HDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDK 2299
Query: 429 RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
E+ R LEC+++ +RW K Q L G KY + +G +LII D D Y
Sbjct: 2300 IAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTY 2359
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWL 547
T D + ++A VEE+ T+ G+ DV +PA C WL
Sbjct: 2360 TC------DAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWL 2413
Query: 548 KDGKEITDLPG-MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDP 606
GK + G + + ++G VH+L+ G F + S A + ++D P +
Sbjct: 2414 L-GKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLT 2472
Query: 607 SVLEALAAHAITVKVGHTAHIKVPFRGKPLPK-VTWYKDGMEVTEEERVSMERGEDQALL 665
LE + V + FR P PK V WYKD ++ E+ M A L
Sbjct: 2473 RPLEPKTGRELQSVV-----LSCDFR--PAPKAVQWYKDDTPLSPSEKFKMSLEGQMAEL 2525
Query: 666 TISNCVREDSGLILLKLKNDHGSATATLHL-------SVLDRPKPPQGRVEF-LELSGSC 717
I + D+G+ + + H S T+ + D +G F ELS
Sbjct: 2526 RILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHED 2585
Query: 718 VHMKWKAPKDNGGRPVTQFIVERRAVGKKSWI---KIGEVDGKVTNFSTNKVEEGKAYQF 774
++W NG E G++ + I D + S+ KV +
Sbjct: 2586 EEVEWSL---NGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEV 2642
Query: 775 RILAVNSEGVSDPLETEE 792
R+ V D L EE
Sbjct: 2643 RVKPVVFLKALDDLSAEE 2660
Score = 133 bits (335), Expect = 1e-30
Identities = 109/462 (23%), Positives = 188/462 (40%), Gaps = 23/462 (4%)
Query: 236 ILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYML 295
+ +PLE K + +VV C + + + W K PL K+ + G L
Sbjct: 2471 LTRPLEPKTGRELQSVVLSC--DFRPAPKAVQWYKDDTPLSPSE---KFKMSLEGQMAEL 2525
Query: 296 VISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKE 355
I + DAG+Y G S E+TV + G ++ + TE A F LS ++
Sbjct: 2526 RILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHED 2585
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTID 415
W NG L D +EI S G HTL +K + +D+G A + + A+L +
Sbjct: 2586 EEVEWSLNGMPLYNDSFHEI--SHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEVR 2643
Query: 416 RIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAEL 475
P+ F+ L ++ +ER L+CE++ + + W+KDG L KY H L
Sbjct: 2644 VKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 476 IIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCV 535
++ D D G YT + + A V V + + + + G
Sbjct: 2704 VVHDVSPEDAGLYTCHVGSE------ETRARVRVHDLHVGITKRLKTMEVLEGESCSFEC 2757
Query: 536 VLNDEKVE--GVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESE 593
VL+ E +W GK + Q +QG + L+ P G+ F +G S+
Sbjct: 2758 VLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSK 2817
Query: 594 ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEER 653
AS+ + + P ++++ L + ++ G P V W KD + + ++
Sbjct: 2818 ASLIVRERPA---AIIKPLEDQWVAPGEDVELRCELSRAGTP---VHWLKDRKAIRKSQK 2871
Query: 654 VSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHL 695
+ A+L I +D+G ++ + +TA+LH+
Sbjct: 2872 YDVVCEGTMAMLVIRGASLKDAGEYTCEV--EASKSTASLHV 2911
Score = 133 bits (334), Expect = 1e-30
Identities = 153/631 (24%), Positives = 249/631 (39%), Gaps = 58/631 (9%)
Query: 70 VEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSI-NKEHVLKLE 128
+E + V EG A FR R+ + W + P+ + D+ HVL L
Sbjct: 3008 IEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDK-TPLHANELNEIDAQPGGYHVLTLR 3066
Query: 129 PLTSDDSDNYKCIASNDHADAIYTVS------------LLVTEGQE--------KMDFKK 168
L DS A + A A V+ +TEG++ D
Sbjct: 3067 QLALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPV 3126
Query: 169 MLKKRAPPAPKKKQKKVANEKEMLEIL-SKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKK 227
K + ++++E ++L + +D + E G ++R
Sbjct: 3127 CWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVR------- 3179
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
V +R + L+D E C++ VK W G LR KY ++
Sbjct: 3180 -VHARPVRFQEALKDLEVLEGGAATLRCVLSSVAAPVK--WCYGNNVLRPG---DKYSLR 3233
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
Q G LV+ N+ D+G YS S GD+ SA LTV P +F+G+++ + TE TA
Sbjct: 3234 QEGAMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATL 3293
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
LSK P W+ + L+ D+Y + +DG L+I+ + D+ E+S G
Sbjct: 3294 RCELSKAAP-VEWRKGSETLRDGDRY--CLRQDGAMCELQIRGLAMVDAAEYSCVCGEER 3350
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A LTI +P F+ L++ E + A L CEL SK + W+K + L G ++S+
Sbjct: 3351 TSASLTIRPMPAHFIGRLRHQESIEGATATLRCEL-SKAAPVEWRKGRESLRDGDRHSLR 3409
Query: 468 HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT 527
+G EL I ++D GEY+ V E ++A +TV+ A G+ + A
Sbjct: 3410 QDGAVCELQICGLAVADAGEYSCVC------GEERTSATLTVKALPAKFTEGLRNEEAVE 3463
Query: 528 GSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
G+ A L C + VE W K + + D + ++G +L + G+Y
Sbjct: 3464 GATAMLWCELSKVAPVE--WRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCV 3521
Query: 587 AKGTESEASVFI-ADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDG 645
+ A++ I A P V A T + + P V W K
Sbjct: 3522 CGQERTSATLTIRALPARFIEDVKNQEAREGATAVLQCELNSAAP--------VEWRKGS 3573
Query: 646 MEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ + +R S+ + + L I D+G
Sbjct: 3574 ETLRDGDRYSLRQDGTKCELQIRGLAMADTG 3604
Score = 124 bits (311), Expect = 6e-28
Identities = 96/357 (26%), Positives = 153/357 (42%), Gaps = 13/357 (3%)
Query: 229 VEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQ 288
VE +A + L + + + T VF C E P + W KG LR GK+ Q
Sbjct: 2911 VEEKANCFTEELTNLQVEEKGTAVFTCKTE--HPAATVTWRKGLLELRAS---GKHQPSQ 2965
Query: 289 MGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFE 348
G L IS + D+ Y+ +G + A+L V + + +++ V V E +A F
Sbjct: 2966 EGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFR 3025
Query: 349 IRLSKKEPNFV-WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
R+S V W + L ++ EI G H L ++ L DSG EAG+
Sbjct: 3026 CRISPANYEPVHWFLDKTPLHANELNEIDAQPGGY-HVLTLRQLALKDSGTIYFEAGDQR 3084
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
A L + P F L + + E L CE ++ D+ + W KDG+ L + ++
Sbjct: 3085 ASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLS 3144
Query: 468 HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT 527
HEG RA+L+I A L D G Y A S++IV V R + + D+
Sbjct: 3145 HEGHRAQLLITGATLQDSGRYKCEA------GGACSSSIVRVHARPVRFQEALKDLEVLE 3198
Query: 528 GSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
G A L VL+ W + + ++GA+ +L+ ++ P+ G+Y+
Sbjct: 3199 GGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255
Score = 123 bits (309), Expect = 1e-27
Identities = 141/665 (21%), Positives = 252/665 (37%), Gaps = 80/665 (12%)
Query: 78 APEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDN 137
A G A V A+ ++W ++ G + S+K+ ++ L ++ D+
Sbjct: 902 AEAGASATLSCEV-AQAQTEVTWYKD-GKKLSSSSKVCMEATGCTRRLVVQQAGQADAGE 959
Query: 138 YKCIASNDH---------------------------ADAIYTVSLLVTEGQEKMDFKKML 170
Y C A A A T+S V + Q ++ + K
Sbjct: 960 YSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYKDG 1019
Query: 171 KKRAPPAPKKKQKKVANEKEMLEILSKVPKKDF------EKVCMEYGFTDFRGLLRKLKE 224
KK + + K + +++ K D+ ++V T+ + + K +
Sbjct: 1020 KKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQS 1079
Query: 225 MKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKY 284
+ +V+ EA + + C E+ ++ W K + L S K
Sbjct: 1080 VHNEVQAEA--------------GASAMLSC--EVAQAQTEVTWYKDGKKLS---SSSKV 1120
Query: 285 DVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMK---PVKVTE 341
++ G LV+ DAG YS G +R+S L + + F E V+
Sbjct: 1121 GMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEA 1180
Query: 342 RQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSA 401
TA+ +++ + W +GK+L K + V G T L ++ +D+GE+S
Sbjct: 1181 GTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVK--GCTRRLVVQQVGKADAGEYSC 1238
Query: 402 EAGNLVQKAQLTIDRIPIKFVSNL---KNVRVKERSRACLECELTSKDVTLRWKKDGQLL 458
EAG QL I F VR + + A L CE+ + W KDG+ L
Sbjct: 1239 EAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKL 1298
Query: 459 MHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYY----STAIVTVEERLA 514
+K + G +L+++ A +D GEYT A G ++ V +E+LA
Sbjct: 1299 SSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA--GGQRLSFHLDVSEPKAVFAKEQLA 1356
Query: 515 TVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPS 574
K V A G+ A L + + E W KDGK+++ +++ G +L+
Sbjct: 1357 HRK-----VQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQ 1411
Query: 575 MGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGK 634
G+Y+ A G S+ +A+P + E + + G + + +
Sbjct: 1412 ACQADTGEYSCEAGGQRLSFSLDVAEPKVV--FAKEQPVHREVQAQAGASTTLSCEV-AQ 1468
Query: 635 PLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLH 694
+V WYKDG +++ +V ME L + + +G + + GS + H
Sbjct: 1469 AQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAG----EYSCEAGSQRLSFH 1524
Query: 695 LSVLD 699
L V +
Sbjct: 1525 LHVAE 1529
Score = 123 bits (308), Expect = 1e-27
Identities = 102/455 (22%), Positives = 184/455 (40%), Gaps = 18/455 (3%)
Query: 230 EVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQM 289
E +A+ + L ++ + + + E+ ++ W K + L S K ++ +
Sbjct: 1345 EPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLS---SSSKVRMEAV 1401
Query: 290 GTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEM---KPVKVTERQTAV 346
G LV+ D G YS G +R+S L V + + F E + V+ +
Sbjct: 1402 GCTRRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTT 1461
Query: 347 FEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+++ + +W +GK+L K + + G T L ++ A + +GE+S EAG+
Sbjct: 1462 LSCEVAQAQTEVMWYKDGKKLSFSSK--VRMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQ 1519
Query: 407 VQKAQLTIDRIPIKFVSNL---KNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTK 463
L + F + V+ + + A L CE+ + W KDG+ L +K
Sbjct: 1520 RLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSK 1579
Query: 464 YSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
M G L++++A +D GEY+ A GD + + + A + +V
Sbjct: 1580 VRMEAVGCTRRLVVQEAGQADAGEYSCKA---GDQRLSFHLHVAEPKVVFAKEQPAHREV 1636
Query: 524 HAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKY 583
A G+ A L + + E W KDGK+++ +++ G +L+ G G+Y
Sbjct: 1637 QAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEY 1696
Query: 584 TFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKP-LPKVTWY 642
+ A G + +A+ ++P + E V H I P VTW
Sbjct: 1697 SCEAGGQRLSFRLHVAE---LEPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWL 1753
Query: 643 KDGMEVTEEERVSMERGEDQALLTISNCVREDSGL 677
KDG+E+ +R D LT+ DS +
Sbjct: 1754 KDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAI 1788
Score = 119 bits (299), Expect = 1e-26
Identities = 110/448 (24%), Positives = 187/448 (41%), Gaps = 32/448 (7%)
Query: 258 ELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRM 317
E+ ++ W K + L S K V+ +G LV+ DAG YS G +R+
Sbjct: 1649 EVAQAQTEVTWYKDGKKLS---SSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRL 1705
Query: 318 SAELTVLD-EPLKFLGEM----KPVKVTERQTAVFEIRLSKKEPNFV-WKFNGKELKRDD 371
S L V + EP + E +P+ V E + + L+ V W +G E++R
Sbjct: 1706 SFRLHVAELEPQ--ISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSK 1763
Query: 372 KYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVK 431
++E + G THTL + A++ DS +S G Q + ++ + KF L+ V +
Sbjct: 1764 RHE--TASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGE 1821
Query: 432 ERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVV 491
L CEL+ + W+ L G ++ M EG L + + D GEY
Sbjct: 1822 LGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCE 1881
Query: 492 AMQDGDPTEYYSTAIVTVE-ERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDG 550
+ D +++A +TV R+ SG+S V A G A V++ V VW +DG
Sbjct: 1882 SRDD------HTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVVWFRDG 1935
Query: 551 KEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLE 610
+ I + GA H L + E G+ T A+G S A++ + + P + LE
Sbjct: 1936 ALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKLE 1995
Query: 611 ALAAH---AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTI 667
++T++V T +P P++ W ++ + + V + + L +
Sbjct: 1996 PQTVEERSSVTLEVELT---------RPWPELRWTRNATALAPGKNVEIHAEGARHRLVL 2046
Query: 668 SNCVREDSGLILLKLKNDHGSATATLHL 695
N D G + +D A T+ +
Sbjct: 2047 HNVGFADRGFFGCETPDDKTQAKLTVEM 2074
Score = 119 bits (298), Expect = 2e-26
Identities = 169/717 (23%), Positives = 269/717 (37%), Gaps = 69/717 (9%)
Query: 229 VEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQ 288
V +R L+ L+ +E T C EL + W KG+ L + KY + Q
Sbjct: 3974 VTAAPVRFLRELQHQEVDEGGTAHLCC--ELSRAGASVEWRKGSLQL---FPCAKYQMVQ 4028
Query: 289 MGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFE 348
G L++ V DAG Y+ G + A L+V KF ++ ++ A
Sbjct: 4029 DGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLC 4088
Query: 349 IRLSKKEPNFV--WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406
+LS E V W G EL KYE+ G T L I D+GE++ G
Sbjct: 4089 CQLSDAESGAVVQWLKEGVELHAGPKYEMR--SQGATRELLIHQLEAKDTGEYACVTGGQ 4146
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVT-LRWKKDGQLLMHGTKYS 465
A L + + V L + V CE++ T ++W G L
Sbjct: 4147 KTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTE 4206
Query: 466 MN-HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524
+ +G+ L ++ D G V+ G+ + S+A +TV T+ + DV
Sbjct: 4207 VAVRDGRIHTLRLKGVTPEDAG---TVSFHLGN---HASSAQLTVRAPEVTILEPLQDVQ 4260
Query: 525 AATGSPAEL-CVVLNDEKVEGVWLKDG-----KEITDLPGMQIVKQGAVHKLIFPSMGPE 578
+ G A C + E W G E+ D+ V+QG +H L + E
Sbjct: 4261 LSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDIT----VEQGTLHLLTLHKVTLE 4316
Query: 579 HEGKYTFRAKGTESEASVFIADPPTIDPSV--LEALAAHAITVKVGHTAHIKVPFRGKPL 636
G +F SEA + + T+ + +EAL G A + +
Sbjct: 4317 DAGTVSFHVGTCSSEAQLKVTAKNTVVRGLENVEALE--------GGEALFECQLSQPEV 4368
Query: 637 PKVTWYKDGMEVTEEERVSMERGED--QALLTISNCVREDSGLILLKLKNDHGSATATLH 694
TW D V E + E+ + LL + N +DS + + SA T+
Sbjct: 4369 AAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFLTVR 4428
Query: 695 LSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSW------ 748
R+E LE +K A + T + E VG+ SW
Sbjct: 4429 ----------GWRLEILE------PLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAA 4472
Query: 749 IKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQP 808
++ + D VT ++ ++ Q + D + + + +PP A
Sbjct: 4473 VQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASARLTVLGLPDPPEDA--- 4529
Query: 809 QVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
+V + VT++W AP DGG + GY VE ++ + W + + + G +C VDGL
Sbjct: 4530 EVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQW-RLCHELVPGPECVVDGLAP 4588
Query: 869 DTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKP----PGLVQDLHVSDSSNSSISL 921
Y FRV AV G G+P +V +P KP P + V+ + S+ L
Sbjct: 4589 GETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSLEL 4645
Score = 115 bits (289), Expect = 2e-25
Identities = 150/682 (21%), Positives = 262/682 (38%), Gaps = 59/682 (8%)
Query: 40 VRRKSSSIVEFFSL-VTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHI 98
++R + IV SL V+ S+ + F++ ++A E + V + + H+
Sbjct: 2619 IQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS-DPEAHV 2677
Query: 99 SWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTV----- 153
W+++ G+ + S K + L + ++ +D+ Y C ++ A V
Sbjct: 2678 VWRKD-GVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHV 2736
Query: 154 -------SLLVTEGQEKMDFKKMLKKRAPPAP-------------KKKQKKVANEKEMLE 193
++ V EG E F+ +L + P + Q K +L
Sbjct: 2737 GITKRLKTMEVLEG-ESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILV 2795
Query: 194 ILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVF 253
+ P E V G T L+ V I+KPLED+ V
Sbjct: 2796 VREAAPSDAGEVVFSVRGLTSKASLI---------VRERPAAIIKPLEDQWVAPGEDVEL 2846
Query: 254 DCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVG 313
C EL + W+K + +R KYDV GT MLVI ++ DAG Y+ V
Sbjct: 2847 RC--ELSRAGTPVHWLKDRKAIRKSQ---KYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901
Query: 314 DKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKY 373
+ +A L V ++ F E+ ++V E+ TAVF + W+ EL+ K+
Sbjct: 2902 ASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKH 2961
Query: 374 EITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKER 433
+ S++GLT L I +DS ++ + G +AQL + + + +L++V V+E
Sbjct: 2962 Q--PSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEG 3019
Query: 434 SRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHE-GKRAELIIEDAQLSDGGEYTVV 491
S A C ++ + + W D L ++ + G L + L D G +
Sbjct: 3020 SSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG---TI 3076
Query: 492 AMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGK 551
+ GD ++A + V E+ + ++D G L + + W KDGK
Sbjct: 3077 YFEAGDQR---ASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGK 3133
Query: 552 EITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEA 611
+ Q+ +G +L+ + G+Y A G S + V + P L+
Sbjct: 3134 TLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD 3193
Query: 612 LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCV 671
L V G A ++ P V W + ++ S+ + L + N
Sbjct: 3194 L-----EVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLR 3247
Query: 672 REDSGLILLKLKNDHGSATATL 693
+DSG + SAT T+
Sbjct: 3248 PQDSGRYSCSFGDQTTSATLTV 3269
Score = 115 bits (287), Expect = 4e-25
Identities = 137/583 (23%), Positives = 228/583 (39%), Gaps = 70/583 (12%)
Query: 261 DPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL----SVGDK- 315
+P ++ W K +P+ ++ + Q G Y L I ++ + D+G Y ++G+
Sbjct: 36 NPTPQVSWEKDQQPVAAG---ARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAF 92
Query: 316 -----RMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLS-KKEPNFVWKFNGKELKR 369
++ AE ++ FL ++V E A F R+ P W +G+ L
Sbjct: 93 AAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGE 152
Query: 370 DDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQ----LTIDRIPIKFVSN- 424
D + V E G L+I+ AR D G + A N + A L +D S
Sbjct: 153 PDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRP 212
Query: 425 -------------------------------LKNVRVKERSRACLECELTS--KDVTLRW 451
+ V E A L C +T K T+ W
Sbjct: 213 GTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETV-W 271
Query: 452 KKDGQLLMHGTKYSMNHEGKRAELI-IEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVE 510
KKDGQL+ G ++ + + + ++ I + SD G YT A T YS+ +V V
Sbjct: 272 KKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT--YSSVLVVVR 329
Query: 511 ERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKL 570
E K + D+ A + E W K+ + I ++G +L
Sbjct: 330 EPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRL 389
Query: 571 IFPSMGPEHEGKYTFRA-KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKV 629
++ + + Y +G+ + A + + ++L L V+VG TA V
Sbjct: 390 TVRNVSADDDAVYICETPEGSRTVAEL------AVQGNLLRKLPRKT-AVRVGDTAMFCV 442
Query: 630 PFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA 689
P+ V W ++ EV RV++ + LTIS C ED G + + S
Sbjct: 443 EL-AVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTST 501
Query: 690 TATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT--QFIVERRAVGKKS 747
+ +PP V + S + + W +P +G RPVT ++VE++ +G +
Sbjct: 502 QFCVSAPRKPPLQPPVDPVVKARMESSVI-LSW-SPPPHGERPVTIDGYLVEKKKLGTYT 559
Query: 748 WIKIGEVDGKVT-NFSTNKVEEGKAYQFRILAVNSEGVSDPLE 789
WI+ E + T + V E +QFR+ A+NS G S LE
Sbjct: 560 WIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLE 602
Score = 110 bits (275), Expect = 9e-24
Identities = 103/451 (22%), Positives = 183/451 (40%), Gaps = 23/451 (5%)
Query: 256 IMELKDPNVKMIWIKGTEPLRIQYSLG-KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGD 314
+ EL D + W+K L S G KY+V+ + +L++ +V +DAG+Y
Sbjct: 727 LAELSDQAAAVTWLKDGRTL----SPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG 782
Query: 315 KRMSAELTVLDEPLKFLGEMKP--VKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDK 372
R++ +L+V +M V A FE S+ + W +G EL
Sbjct: 783 GRIAYQLSVQGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSG- 841
Query: 373 YEITVSED-GLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNL---KNV 428
E + ED G H L D G +S G +L + + F + +
Sbjct: 842 -ERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKL 900
Query: 429 RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
+ + + A L CE+ + W KDG+ L +K M G L+++ A +D GEY
Sbjct: 901 QAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY 960
Query: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLK 548
+ A G + + + A + S+V A G+ A L + + E +W K
Sbjct: 961 SCEA---GGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYK 1017
Query: 549 DGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSV 608
DGK+++ + + +G +L+ G G Y+ A+G + I +P +
Sbjct: 1018 DGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMM--FA 1075
Query: 609 LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTIS 668
E + + + G +A + + +VTWYKDG +++ +V ME L +
Sbjct: 1076 KEQSVHNEVQAEAGASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLP 1134
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLD 699
+ D+G + + G + HL + +
Sbjct: 1135 QAGKADAG----EYSCEAGGQRVSFHLHITE 1161
Score = 107 bits (267), Expect = 8e-23
Identities = 108/475 (22%), Positives = 186/475 (39%), Gaps = 34/475 (7%)
Query: 228 KVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVK 287
+V+ + +++PL DK V +C + V+ W KG++ L+ KY++
Sbjct: 2284 RVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVR--WFKGSQELQPG---PKYELV 2338
Query: 288 QMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVF 347
G L+IS+V+ D Y+ GD + SA+ V ++ + + ++ V V E A F
Sbjct: 2339 SDGLYRKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWF 2398
Query: 348 EIRL---SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAG 404
E S + P W L+ + + ++G H L ++ + +G G
Sbjct: 2399 ECETSIPSVRPPK--WLLGKTVLQAGG--NVGLEQEGTVHRLMLRRTCSTMTGPVHFTVG 2454
Query: 405 NLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKY 464
A+L + IP+ L+ +E L C+ ++W KD L K+
Sbjct: 2455 KSRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKF 2514
Query: 465 SMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524
M+ EG+ AEL I +D G Y A TE VTVE R TV + D
Sbjct: 2515 KMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTE------VTVEAREVTVTGPLQDAE 2568
Query: 525 AATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYT 584
A A L+ E E W +G + + +I +G H L+ S+ G
Sbjct: 2569 ATEEGWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVR 2628
Query: 585 FRAKGTESEASVFIADPPTIDPSVLEALAAH-----AITVKVGHTAHIKVPFRGKPLPKV 639
+ + A + + P + L+ L+A A+ +V P V
Sbjct: 2629 ASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEV-----------SDPEAHV 2677
Query: 640 TWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLH 694
W KDG+++ ++ L + + ED+GL + ++ A +H
Sbjct: 2678 VWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVH 2732
Score = 97.8 bits (242), Expect = 6e-20
Identities = 187/849 (22%), Positives = 324/849 (38%), Gaps = 153/849 (18%)
Query: 329 KFLGEMKPVKVTERQTAVFEIRL-SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLK 387
+FL K V+ + A ++ P W+ + + + ++ + ++DG + L
Sbjct: 11 RFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRL--AQDGDLYRLT 68
Query: 388 IKDARLSDSGEFSAEAGNLVQKAQLTI-----------DRIPIKFVSNLKNVRVKERSRA 436
I D L DSG++ A N + +A + ++ P F+ ++RV+E S A
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAP-HFLLRPTSIRVREGSEA 127
Query: 437 CLECEL-TSKDVTLRWKKDGQLL--MHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVA- 492
C + S + W KDG+ L G + + G+ + L I A+ DGG Y V A
Sbjct: 128 TFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 493 ------------MQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAE-------- 532
+ D D + S + LA ++ + A G+PA
Sbjct: 188 NPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQR-RREAMRAEGAPASPPSTGTRT 246
Query: 533 -----------LCVVLNDEKVEGVWLKDGKEITDLPGMQIV-----KQGAVHKLIFPSMG 576
C V + K E VW KDG+ +T+ G + V ++ V K++F
Sbjct: 247 CTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTE--GRRHVVYEDAQENFVLKILFCKQ- 303
Query: 577 PEHEGKYTFRAKG----TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFR 632
G YT A T S V + +P L+ L + K T +VP
Sbjct: 304 -SDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDL---EVREKESATFLCEVP-- 357
Query: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
+P + W+K+ + + +E + LT+ N +D + + + GS T
Sbjct: 358 -QPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYI--CETPEGSRT-- 412
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGR--PVTQFIVERRA-VGKKSWI 749
V L + G+ + K P+ R F VE VG W+
Sbjct: 413 ---------------VAELAVQGNLLR---KLPRKTAVRVGDTAMFCVELAVPVGPVHWL 454
Query: 750 KIGE---VDGKVTNFSTNKVEEGKAYQFRILAVNSEGV-------SDPLETEEVFAGNPI 799
+ E G+V + EG + I E V D + + P
Sbjct: 455 RNQEEVVAGGRVAISA-----EGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPR 509
Query: 800 EPPGFASQPQVTDVTK----EAVTITWNAPTQDGGAPVL--GYIVERRKKGSNLWVPVNK 853
+PP QP V V K +V ++W+ P G PV GY+VE++K G+ W+ ++
Sbjct: 510 KPP---LQPPVDPVVKARMESSVILSWSPPPH-GERPVTIDGYLVEKKKLGTYTWIRCHE 565
Query: 854 -DPIQGTKCTVDGLLEDTEYEFRVIAVNKAG-------PGQPSVPSSSVVAKDPVKPPGL 905
+ + + TV + E+ ++FRV A+N G PG + + + + P+K
Sbjct: 566 AEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHL-APKLAVRTPLKAVQA 624
Query: 906 VQDLHVSDSSNSSISLAWREPAEGDP-PSGYILEMRAEDTKEWSKCTKIPISGTCYTVGG 964
V+ V+ S + +++ A +G + + E+ + T+ ++P S
Sbjct: 625 VEGGEVTFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPAS-------- 676
Query: 965 LIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTALCI 1024
+ + F + E+ + V G+ A PPAA ++ ARL H + L
Sbjct: 677 -LHGAQLKFVANGI-ESSIRMEVRAAPGLTANKPPAAAAREVLARL--HEEAQLLAELSD 732
Query: 1025 HAAFSGSPPPDVIWQKDG--VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFG 1082
AA V W KDG + + + S L+ R D+G+Y + + G
Sbjct: 733 QAA-------AVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG--G 783
Query: 1083 EARYDIHVR 1091
Y + V+
Sbjct: 784 RIAYQLSVQ 792
Score = 87.8 bits (216), Expect = 6e-17
Identities = 89/375 (23%), Positives = 153/375 (40%), Gaps = 29/375 (7%)
Query: 334 MKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARL 393
+K V+ E F + L+ W +G+ LK YEI D HTL I++
Sbjct: 619 LKAVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSVYEIHC--DRTRHTLTIREVPA 675
Query: 394 SDSGEFSAEAGNLVQKA---------QLTIDRIPIKFVSNLKNVRVKERSRACLECELTS 444
S G N ++ + LT ++ P + + V + A L EL+
Sbjct: 676 SLHGAQLKFVANGIESSIRMEVRAAPGLTANKPP---AAAAREVLARLHEEAQLLAELSD 732
Query: 445 KDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYST 504
+ + W KDG+ L G KY + R L++ D D G Y V+ Y
Sbjct: 733 QAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSR---GGRIAYQL 789
Query: 505 AIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQ 564
++ + L +G S V A G PA+ ++ V W KDG E+ G + +++
Sbjct: 790 SVQGLARFLHKDMAG-SCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGH-SGERFLQE 847
Query: 565 --GAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVG 622
G H+L+ ++ + EG Y+ R + + +++P + E LA + + G
Sbjct: 848 DVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVV--FAKEQLARRKLQAEAG 905
Query: 623 HTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKL 682
+A + + +VTWYKDG +++ +V ME L + + D+G +
Sbjct: 906 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAG----EY 960
Query: 683 KNDHGSATATLHLSV 697
+ G + HL V
Sbjct: 961 SCEAGGQRLSFHLDV 975
Score = 82.4 bits (202), Expect = 3e-15
Identities = 136/661 (20%), Positives = 232/661 (35%), Gaps = 85/661 (12%)
Query: 77 TAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSD 136
T EG A V G KP WK++ + + + Y+ + VLK+ D
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRG 307
Query: 137 NYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANEKEMLEILS 196
Y C ASN GQ ++++ A P K+ Q EKE L
Sbjct: 308 LYTCTASN-------------LVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLC 354
Query: 197 KVPKKDFEK----------VCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKET- 245
+VP+ E +YG + G R+L + +A+ I + E T
Sbjct: 355 EVPQPSTEAAWFKEETRLWASAKYGIEE-EGTERRLTVRNVSADDDAVYICETPEGSRTV 413
Query: 246 -------------------KVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDV 286
+V T +F C+ EL P + W++ E + + G+ +
Sbjct: 414 AELAVQGNLLRKLPRKTAVRVGDTAMF-CV-ELAVPVGPVHWLRNQEEV---VAGGRVAI 468
Query: 287 KQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTV-------LDEPL----------K 329
GT++ L IS + D G + GD + S + V L P+
Sbjct: 469 SAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESS 528
Query: 330 FLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIK 389
+ P ER + + KK+ E + E+TV++ + +
Sbjct: 529 VILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFR 588
Query: 390 DARLSDSGEFS-AEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVT 448
+ L+ G+ E V A R P LK V+ E +LT
Sbjct: 589 VSALNSFGQSPYLEFPGTVHLAPKLAVRTP------LKAVQAVEGGEVTFSVDLTVASAG 642
Query: 449 LRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGG---EYTVVAMQDGDPTEYYSTA 505
W DGQ L + Y ++ + R L I + S G ++ ++ E +
Sbjct: 643 -EWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAP 701
Query: 506 IVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQG 565
+T + A + +V A A+L L+D+ WLKDG+ ++ P ++
Sbjct: 702 GLTANKPPA---AAAREVLARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASA 758
Query: 566 AVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTA 625
L+ + + G Y ++G + + + + + +A + G A
Sbjct: 759 GRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQG---LARFLHKDMAGSCVDAVAGGPA 815
Query: 626 HIKVPFRGKPLPKVTWYKDGMEVTEE-ERVSMERGEDQALLTISNCVREDSGLILLKLKN 684
+ + V WYKDGME+ ER E + L + R+D G ++
Sbjct: 816 QFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGE 874
Query: 685 D 685
D
Sbjct: 875 D 875
Score = 66.6 bits (161), Expect = 1e-10
Identities = 67/272 (24%), Positives = 101/272 (37%), Gaps = 25/272 (9%)
Query: 1016 VRAGTALCIHAAFSGSPPP-DVIWQKDGV---PTKGRETITKSKNHSQFLINSTKRSDSG 1071
VRAG C S + P + W +G P T+T +H L+ S + +G
Sbjct: 4443 VRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAG 4502
Query: 1072 VYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYI 1131
++ AR + V P PP + + +TVTL+W G Y
Sbjct: 4503 EVTFACRDAVASAR----LTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYR 4558
Query: 1132 IMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINK 1191
+ ++ +T W E V + V GL PG Y FRV A +G EP ++
Sbjct: 4559 VEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEP--------VHL 4610
Query: 1192 DQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDV 1251
Q L+ KP P + + V G+D ++ + V +KG
Sbjct: 4611 PQTVRLAEPPKP--------VPPQPSAPESRQVAAGEDVSLELEVVAE-AGEVIWHKGME 4661
Query: 1252 NITANSKFWYNSTSGVCTLVIPTCTLKDSGDY 1283
I +F S LVI T +D G+Y
Sbjct: 4662 RIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693
Score = 60.8 bits (146), Expect = 8e-09
Identities = 103/449 (22%), Positives = 178/449 (39%), Gaps = 103/449 (22%)
Query: 412 LTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEG 470
LT D P+ F++ L+N V++ +C +T + + ++RW KDG+LL Y +N +
Sbjct: 5120 LTSDAAPV-FLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178
Query: 471 KRA-ELIIEDAQLSDGGEYTVVAMQD----------------------GDPTE---YYS- 503
+ +LII +D G Y +A D TE Y+S
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238
Query: 504 -----------TAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGV------W 546
T T E +L V + D+ A G+ + KV+G W
Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQL----KVKGYPAPRLYW 5294
Query: 547 LKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTF---RAKGTE-SEASVFIADPP 602
KDG+ +T +++ + +H L S+ E G+Y A G S A + + P
Sbjct: 5295 FKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD 5354
Query: 603 T-------------IDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVT 649
+ P +LE VK G + V G+P+P V W ++
Sbjct: 5355 EPEEKPASDVHEQLVPPRMLERFTPKK--VKKGSSITFSVKVEGRPVPTVHWLRE----- 5407
Query: 650 EEERVSMERGEDQALLTISNCVREDSGLILLKLKNDH------------GSA--TATLHL 695
E ER + G D T+++ ++ S L+LL + H G A +A+LH+
Sbjct: 5408 EAERGVLWIGPDTPGYTVASSAQQHS-LVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466
Query: 696 SVLDRPKPPQGRVEFL---ELSG-----SCVHMKWKAPKDNGGRPVTQFIVERRAVGKKS 747
S L + + + E L L G S ++ + D GG+ + + + A+G S
Sbjct: 5467 SGLPKVEEQEKVKEALISTFLQGTTQAISAQGLETASFADLGGQRKEEPLAAKEALGHLS 5526
Query: 748 WIKIG------EVDGKVTNFSTNKVEEGK 770
++G ++ ++T + K+ + K
Sbjct: 5527 LAEVGTEEFLQKLTSQITEMVSAKITQAK 5555
Score = 60.1 bits (144), Expect = 1e-08
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 903 PGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCY 960
P +D V S+ +++L+W P G GY +E++ T +W C ++ C
Sbjct: 4523 PDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPEC- 4581
Query: 961 TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGT 1020
V GL + Y FR+ AV G GEPV L + VR PP SA +
Sbjct: 4582 VVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDV 4641
Query: 1021 ALCIHAAFSGSPPPDVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
+L + +VIW K + + GR + +I D G Y
Sbjct: 4642 SLELEVVAEAG---EVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693
Score = 53.1 bits (126), Expect = 2e-06
Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNS--TSGVCTL 1270
PRFV ++ + G+D TC G P P + YK +T +KF S SG+ L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
VI + +D G Y + N LG R+S L +
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/91 (32%), Positives = 44/91 (48%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLV 1271
APRF+T K V G+D T++C +GNP P V+ K + A ++F + L
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLT 68
Query: 1272 IPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
I L DSG Y N +G+ ++ L V
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 52.4 bits (124), Expect = 3e-06
Identities = 58/201 (28%), Positives = 87/201 (43%), Gaps = 18/201 (8%)
Query: 618 TVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG-EDQALLTISNCVREDSG 676
TV +G + + +P + TW KDG + RV + ++ LLTI V ED G
Sbjct: 7473 TVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLG 7532
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
+ + N G+ T T L +RP + E+ V + WK + G PVT +
Sbjct: 7533 VYTCSVSNALGTVTTTGVLRKAERPS-SSPCPDIGEVYADGVLLVWKPVESYG--PVT-Y 7588
Query: 737 IVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGV---SDPLETEEV 793
IV+ G SW + D + T+K+ G Y FR V+ G+ S P +E+V
Sbjct: 7589 IVQCSLEG-GSWTTLAS-DIFDCCYLTSKLSRGGTYTFRTACVSKAGMGPYSSP--SEQV 7644
Query: 794 FAGNPI------EPPGFASQP 808
G P E G ++QP
Sbjct: 7645 LLGGPSHLASEEESQGRSAQP 7665
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 12/122 (9%)
Query: 583 YTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWY 642
YT++A T + A PP++ ++ + A + G TA + G P P VTWY
Sbjct: 6344 YTYQAIDTHT------ARPPSMQVTIEDVQA------QTGGTAQFEAIIEGDPQPSVTWY 6391
Query: 643 KDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPK 702
KD +++ + R+S ++ L + + +D+G+ +N G L VL
Sbjct: 6392 KDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 6451
Query: 703 PP 704
P
Sbjct: 6452 EP 6453
Score = 48.9 bits (115), Expect = 3e-05
Identities = 56/227 (24%), Positives = 78/227 (34%), Gaps = 20/227 (8%)
Query: 964 GLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSA-----------RLKS 1012
GL ER K + ++ G P L+K P F LS R S
Sbjct: 7413 GLRERVKA--SVEHISRILKGRPEGLEKEGPPRKKPGLASFRLSGLKSWDRAPTFLRELS 7470
Query: 1013 HMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKS---KNHSQFLINSTKRSD 1069
V G ++ + S P W KDG P + + S KN I D
Sbjct: 7471 DETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAED 7530
Query: 1070 SGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAH 1129
GVY + N G +R A+ P + E + V L W V+ G
Sbjct: 7531 LGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWK---PVESYGPVT 7587
Query: 1130 YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIG 1176
YI+ + +W T A +F Y + L G Y FR ++ G
Sbjct: 7588 YIV-QCSLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAG 7633
Score = 48.5 bits (114), Expect = 4e-05
Identities = 33/139 (23%), Positives = 62/139 (44%), Gaps = 7/139 (5%)
Query: 35 VGEEVVRRKSSSIVEFFSLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNA 94
V VVR + + ++ T ++ P+ E V+ A G A F A ++G+
Sbjct: 6331 VHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIEDVQ------AQTGGTAQFEAIIEGDP 6384
Query: 95 KPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVS 154
+P ++W ++S + + +S ++ + L L + S D+ Y C+A N +
Sbjct: 6385 QPSVTWYKDS-VQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAE 6443
Query: 155 LLVTEGQEKMDFKKMLKKR 173
LLV G + D +K +R
Sbjct: 6444 LLVLGGDNEPDSEKQSHRR 6462
Score = 48.1 bits (113), Expect = 5e-05
Identities = 47/182 (25%), Positives = 68/182 (37%), Gaps = 6/182 (3%)
Query: 520 MSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQ-GAVHKLIFPSMGP 577
++D A G +L C V K W KDGK + P +++ LI S+
Sbjct: 6020 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 6079
Query: 578 EHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLP 637
G+Y A S + P + + A G A G P P
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVE--GEDAQFTCTIEGAPYP 6137
Query: 638 KVTWYKDGMEVTEEERVS--MERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHL 695
++ WYKDG +T + E +L I +ED GL +L N GSA A+ L
Sbjct: 6138 QIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAEL 6197
Query: 696 SV 697
+
Sbjct: 6198 RI 6199
Score = 45.8 bits (107), Expect = 3e-04
Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 7/125 (5%)
Query: 38 EVVRRKSSSIVEFFSLVTRSSNIPAG--DSVPEFVEKPQPVTAPEGDKAVFRARVQGNAK 95
+ V R ++I E F+ V + A + P F+ +P + EG +A FR RV G+ +
Sbjct: 79 QYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPR 138
Query: 96 PHISWKRES---GIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYT 152
P +SW ++ G P + ++ + + + L++ D Y+ A N A
Sbjct: 139 PAVSWSKDGRRLGEP--DGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAA 196
Query: 153 VSLLV 157
+L+V
Sbjct: 197 AALVV 201
Score = 44.7 bits (104), Expect = 6e-04
Identities = 61/263 (23%), Positives = 100/263 (38%), Gaps = 36/263 (13%)
Query: 1029 SGSPPPDVIWQKDG-VPTKGRETITKSKNHSQFLIN--STKRSDSGVYRILLQNEFGEAR 1085
+G P P+ +W+KDG + T+GR + F++ K+SD G+Y N G+
Sbjct: 262 TGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTY 321
Query: 1086 YDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDAST-ATWYT 1144
+ V V + P P RL +V+E A ++ ST A W+
Sbjct: 322 SSVLVVVRE-PAVPFKKRL-------------QDLEVREKESATFLCEVPQPSTEAAWFK 367
Query: 1145 AAERVF-SNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKP 1203
R++ S KY + R R+ RN D + + ++ + A+L
Sbjct: 368 EETRLWASAKYGIEEEGTER----RLTVRNVSADDDAV-----YICETPEGSRTVAEL-A 417
Query: 1204 YEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNS 1263
+ R PR T +R D M C L P V + + A + ++
Sbjct: 418 VQGNLLRKLPR-------KTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISA 470
Query: 1264 TSGVCTLVIPTCTLKDSGDYSVL 1286
TL I C L+D G + +
Sbjct: 471 EGTRHTLTISQCCLEDVGQVAFM 493
Score = 43.5 bits (101), Expect = 0.001
Identities = 30/111 (27%), Positives = 45/111 (40%), Gaps = 1/111 (0%)
Query: 1207 KDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNST-S 1265
K W AP F+ L TV+ GQ T+ C P T K + ++S+ ++T
Sbjct: 7457 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 7516
Query: 1266 GVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
L I +D G Y+ V N LG ++ L ++ S I E
Sbjct: 7517 NFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGE 7567
Score = 42.0 bits (97), Expect = 0.004
Identities = 31/108 (28%), Positives = 42/108 (38%), Gaps = 2/108 (1%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYN-STSGVCTL 1270
AP F+T L+ V G + C G P P+V +K + + + N G L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTV-YDKDDKSVVASITES 1317
+I D G Y L EN +G + L V D A TES
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATES 5232
Score = 41.6 bits (96), Expect = 0.005
Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 1/97 (1%)
Query: 61 PAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSIN 120
P P F+ +P+ G A ++ GN P +SW+++ P+ A+
Sbjct: 4 PQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQ-PVAAGARFRLAQDG 62
Query: 121 KEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV 157
+ L + L DS Y C A N +A V L V
Sbjct: 63 DLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 41.2 bits (95), Expect = 0.007
Identities = 71/302 (23%), Positives = 114/302 (37%), Gaps = 44/302 (14%)
Query: 438 LECELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGK-RAELIIEDAQLSDGGEYTVVAMQD 495
LEC + SK DV RW KDG L G + ++ G L+I +D G YT
Sbjct: 4917 LECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNK 4976
Query: 496 GDPTEYYSTAIVTVEERLATVKSG--MSDVHAA----------TGSPAE-----LCVVLN 538
+ + +V+ E A SG + D T SPAE L + +
Sbjct: 4977 FGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSAD 5036
Query: 539 DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKL---------IFPSMGPEHEGKYTF---- 585
+ E D + + ++ A+ + +F ++G E K
Sbjct: 5037 EGPAEPEEPADWQTYREDEHFICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPR 5096
Query: 586 RAKGTESEASVFIADPPTIDPSVLEALAAHAITVKV-------GHTAHIKVPFRGKPLPK 638
R + S+ + PP PS+L + AA ++ G+ G+P+P
Sbjct: 5097 RVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPS 5156
Query: 639 VTWYKDGMEVTEEERVSMERGEDQA---LLTISNCVREDSGLILLKLKNDHGSATATLHL 695
V W+KDG + E++ + EDQ L I+ V D G+ +N G ++ L
Sbjct: 5157 VRWFKDGKLLEEDDHYMI--NEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAEL 5214
Query: 696 SV 697
V
Sbjct: 5215 RV 5216
Score = 40.4 bits (93), Expect = 0.011
Identities = 24/78 (30%), Positives = 35/78 (44%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
P+F E+ TA G+ RV G KP ISW ++ + I + + L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 127 LEPLTSDDSDNYKCIASN 144
L+ LT DS Y C A++
Sbjct: 6074 LDSLTGVDSGQYMCFAAS 6091
Score = 39.3 bits (90), Expect = 0.025
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 13/127 (10%)
Query: 66 VPEFVEKPQPVTAPEGDK-AVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV 124
+P+ VE+ + + G + A F+ +V+G P + W ++ G P+ SA I H
Sbjct: 5259 LPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKD-GQPLTASAHIRMTDKKILHT 5317
Query: 125 LKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV-----------TEGQEKMDFKKMLKKR 173
L++ +T +DS Y SN A + LLV ++ E++ +ML++
Sbjct: 5318 LEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERF 5377
Query: 174 APPAPKK 180
P KK
Sbjct: 5378 TPKKVKK 5384
Score = 38.9 bits (89), Expect = 0.033
Identities = 36/141 (25%), Positives = 62/141 (43%), Gaps = 9/141 (6%)
Query: 355 EPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEF----SAEAGNLVQKA 410
+P W +GK ++ D + + DG + L + DSG++ ++ AGN
Sbjct: 6042 KPVISWYKDGKAVQVDPHHILIEDPDG-SCALILDSLTGVDSGQYMCFAASAAGNCSTLG 6100
Query: 411 QLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVT-LRWKKDGQLLMHGTKYSMNHE 469
++ + ++P +FV+ ++ E A C + +RW KDG LL G K+ E
Sbjct: 6101 KILV-QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 6159
Query: 470 GKRA--ELIIEDAQLSDGGEY 488
+ L+I A D G Y
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLY 6180
Score = 38.5 bits (88), Expect = 0.043
Identities = 26/124 (20%), Positives = 51/124 (41%), Gaps = 2/124 (1%)
Query: 1187 WLINKDQIQDLSAKLKPYEKKDWRHA--PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTV 1244
W ++ +++ + + Y+ D A P ++ G G+P+P+V
Sbjct: 6329 WDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSV 6388
Query: 1245 TLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
T YK V + +++ +LV+ KD+G Y+ L +N G+ L V
Sbjct: 6389 TWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLG 6448
Query: 1305 KDDK 1308
D++
Sbjct: 6449 GDNE 6452
Score = 38.5 bits (88), Expect = 0.043
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 8/89 (8%)
Query: 240 LEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISN 299
+ED + + T F+ I+E DP + W K + L L + +Q GT Y LV+ +
Sbjct: 6363 IEDVQAQTGGTAQFEAIIE-GDPQPSVTWYKDSVQLVDSTRLSQ---QQEGTTYSLVLRH 6418
Query: 300 VNMNDAGIYSL----SVGDKRMSAELTVL 324
V DAG+Y+ + G AEL VL
Sbjct: 6419 VASKDAGVYTCLAQNTGGQVLCKAELLVL 6447
Score = 38.1 bits (87), Expect = 0.056
Identities = 68/325 (20%), Positives = 112/325 (34%), Gaps = 53/325 (16%)
Query: 1015 VVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKG--RETITKSKNHSQFLINSTKRSDSGV 1072
VV G + G+P P V W+KD P R + + + + I DSG
Sbjct: 20 VVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQ 79
Query: 1073 YRILLQNEFGEARYDIHVRV----------ADFPRPPTNLRLFEEVPNTV---------- 1112
Y +N GEA + ++V F PT++R+ E T
Sbjct: 80 YVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRP 139
Query: 1113 TLTWNHS------PD-----VQEDGEAHYIIMK--RDASTATWYTAAERVFSNKYTVTGL 1159
++W+ PD V+E GEA + ++ R T+ AE L
Sbjct: 140 AVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAAL 199
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPL 1219
+ DS+ D+ + + + + + + A T
Sbjct: 200 ---------------VVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGT 244
Query: 1220 KPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSK--FWYNSTSGVCTLVIPTCTL 1277
+ TV G+ ++C G P+P T++K D + + Y L I C
Sbjct: 245 RTCTVTEGKHARLSCYVTGEPKPE-TVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ 303
Query: 1278 KDSGDYSVLVENELGKDRSSCTLTV 1302
D G Y+ N +G+ SS + V
Sbjct: 304 SDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 38.1 bits (87), Expect = 0.056
Identities = 98/500 (19%), Positives = 179/500 (35%), Gaps = 92/500 (18%)
Query: 64 DSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEH 123
D+ P F+ + Q +G F V G P + W ++ + ++ + + H
Sbjct: 5123 DAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH 5182
Query: 124 VLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQK 183
L + + D Y+C+A N ++ + T+ + ++D A A +
Sbjct: 5183 QLIITAVVPADMGVYRCLAEN-------SMGVSSTKAELRVDLTSTDYDTAADATESSSY 5235
Query: 184 KVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDK 243
A LS ++ E TD E + ++++ L D
Sbjct: 5236 FSAQ-----GYLSSREQEGTEST------TD---------------EGQLPQVVEELRDL 5269
Query: 244 ETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMN 303
+ T + + P ++ W K +PL + D K + T L I +V
Sbjct: 5270 QVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHT---LEIISVTRE 5326
Query: 304 DAGIY----SLSVGDKRMSAELTVL--DE--------------PLKFLGEMKPVKVTERQ 343
D+G Y S ++G SA L V DE P + L P KV +
Sbjct: 5327 DSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGS 5386
Query: 344 TAVFEIRL-SKKEPNFVWKFNGKELKR------DDKYEITVSEDGLTHTLKIKDARLSDS 396
+ F +++ + P W +E +R D TV+ H+L + D
Sbjct: 5387 SITFSVKVEGRPVPTVHWL--REEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQ 5444
Query: 397 GEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQ 456
G ++ A N +A + VS L V +E+ + L
Sbjct: 5445 GTYTCIASNAAGQALCSAS----LHVSGLPKVEEQEKVKEALI----------------S 5484
Query: 457 LLMHGTKYSMNHEGKRAELIIEDAQLSD-GGEYTVVAMQDGDPTEYYSTAIVTVEERLAT 515
+ GT +++ +G +E A +D GG+ + + + S A V EE L
Sbjct: 5485 TFLQGTTQAISAQG------LETASFADLGGQRKEEPLAAKEALGHLSLAEVGTEEFLQK 5538
Query: 516 VKSGMSDVHAATGSPAELCV 535
+ S ++++ +A + A+L V
Sbjct: 5539 LTSQITEMVSAKITQAKLQV 5558
Score = 37.7 bits (86), Expect = 0.074
Identities = 39/172 (22%), Positives = 63/172 (36%), Gaps = 13/172 (7%)
Query: 1129 HYIIMK--RDASTATWYTAAERVFSNKYTVTGL-----LPGRKYYFRVVARNEIGDSEPL 1181
H +I K RD+ T T VF N ++ + + G F V E + L
Sbjct: 5928 HLVICKPRRDSRTDT----VSYVFRNMMKLSSIDLNDQVEGDDRAFEVWQEREDSVRKYL 5983
Query: 1182 DSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPR 1241
T +I ++++ + WR P F L T G+ + C G P+
Sbjct: 5984 LQARTAIIKSSWVKEICGIQQRLALPVWR-PPDFEEELADCTAELGETVKLACRVTGTPK 6042
Query: 1242 PTVTLYKGDVNITAN-SKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELG 1292
P ++ YK + + G C L++ + T DSG Y + G
Sbjct: 6043 PVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAG 6094
Score = 37.7 bits (86), Expect = 0.074
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Query: 501 YYSTAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGM 559
Y AI T R +++ + DV A TG A+ ++ D + W KD ++ D +
Sbjct: 6344 YTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRL 6403
Query: 560 QIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
++G + L+ + + G YT A+ T
Sbjct: 6404 SQQQEGTTYSLVLRHVASKDAGVYTCLAQNT 6434
Score = 37.4 bits (85), Expect = 0.096
Identities = 56/279 (20%), Positives = 102/279 (36%), Gaps = 42/279 (15%)
Query: 1032 PPPDVIWQKDGVPT--KGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEAR---Y 1086
P V+W+KDGV + + +++ D+G+Y + +E AR +
Sbjct: 2673 PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVH 2732
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAA 1146
D+HV + L+ E + E ++ AS +T
Sbjct: 2733 DLHVGITK------RLKTMEVLEG-------------ESCSFECVLSHESASDPAMWTVG 2773
Query: 1147 ERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEK 1206
+ + GRKY V ++ P D+ + ++ L++K +
Sbjct: 2774 GKTVGSSSRFQATRQGRKYILVV------REAAPSDAGEVVF----SVRGLTSKASLIVR 2823
Query: 1207 KDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG 1266
+ + PL+ V G+D + C L V K I + K+
Sbjct: 2824 E---RPAAIIKPLEDQWVAPGEDVELRCE-LSRAGTPVHWLKDRKAIRKSQKYDVVCEGT 2879
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDK 1305
+ LVI +LKD+G+Y+ VE +S+ +L V +K
Sbjct: 2880 MAMLVIRGASLKDAGEYTCEVE----ASKSTASLHVEEK 2914
Score = 37.4 bits (85), Expect = 0.096
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 1030 GSPPPDVIWQKDG-VPTKGRETITKSKNHSQFL---INSTKRSDSGVYRILLQNEFGEAR 1085
G+P P + W KDG + T G + T S+ S L I + + D G+Y L N G AR
Sbjct: 6133 GAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSAR 6192
Query: 1086 YDIHVRV 1092
+R+
Sbjct: 6193 ASAELRI 6199
Score = 36.2 bits (82), Expect = 0.21
Identities = 33/134 (24%), Positives = 55/134 (41%), Gaps = 23/134 (17%)
Query: 982 GVGEPVEL-DKGVRAM--------PPPAAPKFDLSARLKS-----------HMVVRAGTA 1021
G+G ++L ++G R + P P P L + L S + V+ G
Sbjct: 5083 GIGVEIKLVEQGPRRVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYP 5142
Query: 1022 LCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHS---QFLINSTKRSDSGVYRILLQ 1078
+ +G P P V W KDG + + +++ Q +I + +D GVYR L +
Sbjct: 5143 VSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAE 5202
Query: 1079 NEFGEARYDIHVRV 1092
N G + +RV
Sbjct: 5203 NSMGVSSTKAELRV 5216
Score = 35.8 bits (81), Expect = 0.28
Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 11/107 (10%)
Query: 1215 FVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPT 1274
F+ L+ + G T+ C L P V KG ++ + VC L I
Sbjct: 3364 FIGRLRHQESIEGATATLRCE-LSKAAP-VEWRKGRESLRDGDRHSLRQDGAVCELQICG 3421
Query: 1275 CTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQKK 1321
+ D+G+YS + G++R+S TLTV K++ A TE L+ +
Sbjct: 3422 LAVADAGEYSCV----CGEERTSATLTV-----KALPAKFTEGLRNE 3459
Score = 35.4 bits (80), Expect = 0.37
Identities = 21/70 (30%), Positives = 33/70 (47%)
Query: 1238 GNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSS 1297
G P P + +K +TA++ + TL I + T +DSG Y+ + N +G SS
Sbjct: 5286 GYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSS 5345
Query: 1298 CTLTVYDKDD 1307
L V D+
Sbjct: 5346 ARLLVRGPDE 5355
Score = 35.0 bits (79), Expect = 0.48
Identities = 20/89 (22%), Positives = 38/89 (42%), Gaps = 7/89 (7%)
Query: 589 GTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEV 648
G + ++ + PP + + + T ++G T + G P P ++WYKDG V
Sbjct: 6001 GIQQRLALPVWRPPDFEEELADC------TAELGETVKLACRVTGTPKPVISWYKDGKAV 6054
Query: 649 -TEEERVSMERGEDQALLTISNCVREDSG 676
+ + +E + L + + DSG
Sbjct: 6055 QVDPHHILIEDPDGSCALILDSLTGVDSG 6083
Score = 34.7 bits (78), Expect = 0.62
Identities = 31/100 (31%), Positives = 43/100 (43%), Gaps = 5/100 (5%)
Query: 800 EPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGT 859
E P + P + +V + V + W P + G PV YIV+ +G + W + D
Sbjct: 7555 ERPSSSPCPDIGEVYADGVLLVWK-PVESYG-PVT-YIVQCSLEGGS-WTTLASDIFDCC 7610
Query: 860 KCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDP 899
T L Y FR V+KAG G S PS V+ P
Sbjct: 7611 YLT-SKLSRGGTYTFRTACVSKAGMGPYSSPSEQVLLGGP 7649
Score = 34.3 bits (77), Expect = 0.82
Identities = 70/311 (22%), Positives = 117/311 (37%), Gaps = 43/311 (13%)
Query: 265 KMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVL 324
++IW KG E RIQ G+++V G + MLVI D G Y + A+ ++
Sbjct: 4653 EVIWHKGME--RIQPG-GRFEVVSQGRQQMLVIKGFTAEDQGEYHCGL------AQGSIC 4703
Query: 325 DEPLKFLGEMKPVKVTER-QTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLT 383
F + P V E Q ++ + + + +W+ + KR E T+ D ++
Sbjct: 4704 PAAATFQVALSPASVDEAPQPSLPPEAAQEGDLHLLWEALAR--KRRMSREPTL--DSIS 4759
Query: 384 HTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELT 443
L +D R + + E + + T D + ++L + + SRA
Sbjct: 4760 E-LPEEDGRSQRLPQEAEEVAPDLSEGYSTADELARTGDADLSHTSSDDESRA------G 4812
Query: 444 SKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQD------GD 497
+ + KK G+ GT + G A ++ Q + + D GD
Sbjct: 4813 TPSLVTYLKKAGR---PGTSPLASKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGD 4869
Query: 498 PTEYYSTAIVTVEERLATVKSGMS------------DVHAATGSPAEL-CVVLNDEKVEG 544
P+ + + + V+ M D A G L CVV + V
Sbjct: 4870 PSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRA 4929
Query: 545 VWLKDGKEITD 555
WLKDG E+TD
Sbjct: 4930 RWLKDGVELTD 4940
Score = 33.9 bits (76), Expect = 1.1
Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 3/67 (4%)
Query: 1019 GTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQF--LINSTKRSDSGVYRIL 1076
GTA A G P P V W KD V +++ + + + ++ D+GVY L
Sbjct: 6372 GTAQ-FEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCL 6430
Query: 1077 LQNEFGE 1083
QN G+
Sbjct: 6431 AQNTGGQ 6437
Score = 33.5 bits (75), Expect = 1.4
Identities = 23/105 (21%), Positives = 43/105 (40%), Gaps = 10/105 (9%)
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKD---------GVPTKGRETITKSKNHSQFLINSTK 1066
V+ G+++ G P P V W ++ G T G + ++ HS L++
Sbjct: 5382 VKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLD-VG 5440
Query: 1067 RSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNT 1111
R G Y + N G+A + V+ P+ ++ E + +T
Sbjct: 5441 RQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALIST 5485
Score = 33.1 bits (74), Expect = 1.8
Identities = 15/49 (30%), Positives = 22/49 (44%)
Query: 448 TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDG 496
++ W KD L+ T+ S EG L++ D G YT +A G
Sbjct: 6387 SVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTG 6435
Score = 32.7 bits (73), Expect = 2.4
Identities = 22/104 (21%), Positives = 42/104 (40%), Gaps = 7/104 (6%)
Query: 42 RKSSSIVEFFSLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWK 101
RK + F R S + + D P F+ + T G +V +W
Sbjct: 7443 RKKPGLASF-----RLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWS 7497
Query: 102 RESGIPIKESAKIFYDSINKE-HVLKLEPLTSDDSDNYKCIASN 144
++ G P++ S+++ + K +L + + ++D Y C SN
Sbjct: 7498 KD-GAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSN 7540
Score = 32.3 bits (72), Expect = 3.1
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 1214 RFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIP 1273
RF+ +K G + C L P V KG + ++ C L I
Sbjct: 3803 RFIEDVKNQEAREGATAVLQCE-LSKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQIH 3860
Query: 1274 TCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
++ D+G+YS + G++R+S TLTV
Sbjct: 3861 GLSVADTGEYSCV----CGQERTSATLTV 3885
Score = 32.3 bits (72), Expect = 3.1
Identities = 25/72 (34%), Positives = 27/72 (37%), Gaps = 3/72 (4%)
Query: 1016 VRAGTALC-IHAAFSGSPPPDVIWQKDGVPTKGRETI--TKSKNHSQFLINSTKRSDSGV 1072
V GT L G P P + W KDG P I T K I S R DSG
Sbjct: 5271 VAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQ 5330
Query: 1073 YRILLQNEFGEA 1084
Y + N G A
Sbjct: 5331 YAAYISNAMGAA 5342
Score = 32.0 bits (71), Expect = 4.0
Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Query: 620 KVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMER-GEDQALLTISNCVREDSGLI 678
+VG ++ K + W KDG+E+T+ +++ G+ L I+ R D+G
Sbjct: 4910 QVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCY 4969
Query: 679 LLKLKNDHGSAT 690
++ N G T
Sbjct: 4970 TCQVSNKFGQVT 4981
Score = 31.6 bits (70), Expect = 5.3
Identities = 25/108 (23%), Positives = 43/108 (39%), Gaps = 11/108 (10%)
Query: 1214 RFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIP 1273
RF+ +K G + C N V KG + ++ C L I
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIR 3596
Query: 1274 TCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQKK 1321
+ D+G+YS + G++R+S LTV +++ TE L+ +
Sbjct: 3597 GLAMADTGEYSCV----CGQERTSAMLTV-----RALPIKFTEGLRNE 3635
>gi|155969693 myomesin family, member 3 [Homo sapiens]
Length = 1437
Score = 164 bits (414), Expect = 7e-40
Identities = 148/603 (24%), Positives = 249/603 (41%), Gaps = 62/603 (10%)
Query: 639 VTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVL 698
+ W++DG + R + + QA L +S +ED GL ++++ + G + ++ V
Sbjct: 304 IQWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVR 363
Query: 699 DRPKPPQG------RVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIG 752
D G V L+++ C+ + W P D G P+T + +ER WI
Sbjct: 364 DAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACH 423
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFA----------------- 795
E G + EG++Y+FR+ A++ G S P + E+
Sbjct: 424 EAPGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDL 483
Query: 796 GNPIEPPGFASQPQVT-----------DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKG 844
GN I A + VT ++ + V + W P+ AP L Y +E+ G
Sbjct: 484 GNKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRDRAP-LTYSLEKSVIG 542
Query: 845 SNLWVPVNKD-PIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDP---V 900
S W ++ + P++ + V L + Y FRV A+N+ G PS PS + + P +
Sbjct: 543 SGTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATL 602
Query: 901 KPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCY 960
PP VQ + +S+SL W +P + GY + R T EW PI GT +
Sbjct: 603 PPPAQVQAFR---DTQTSVSLTW-DPVKDPELLGYYIYSRKVGTSEWQTVNNKPIQGTRF 658
Query: 961 TVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVR---AMPPPAAP-KFDLSARLKSHMVV 1016
TV GL ++Y F +R+V+EAGVGE + +R A+ P+AP F L K+ MV+
Sbjct: 659 TVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVI 718
Query: 1017 ------RAGTALCIHAAFSGSPPPDVIW---QKDGVPTKGRETITKSKNHSQFLINSTKR 1067
R G + ++ W + +PT+ + + H + +
Sbjct: 719 GWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPTRVCKVSDLHEGHF-YEFRARAA 777
Query: 1068 SDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGE 1127
+ +GV + + E + P PP ++R E ++ L W +
Sbjct: 778 NWAGVGELSAPSSLFECK----EWTMPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPV 833
Query: 1128 AHYIIMKRDASTATWYTAAERVFSNKY-TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDT 1186
Y + ++ + W S + V+ L PG+ Y F+V A N G +P D
Sbjct: 834 TGYHVSFQEEGSEQWKPVTPGPISGTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDP 893
Query: 1187 WLI 1189
L+
Sbjct: 894 VLL 896
Score = 152 bits (385), Expect = 2e-36
Identities = 161/639 (25%), Positives = 256/639 (40%), Gaps = 76/639 (11%)
Query: 703 PPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFS 762
PP +V+ + + V + W KD + + + R VG W + + T F+
Sbjct: 603 PPPAQVQAFRDTQTSVSLTWDPVKDP---ELLGYYIYSRKVGTSEWQTVNNKPIQGTRFT 659
Query: 763 TNKVEEGKAYQFRILAVNSEGV------SDPLETEEVFAGNPIEPPGFASQPQVTDVTKE 816
+ GK Y+F + +V+ GV ++P+ ++ A P P GFA + + K
Sbjct: 660 VPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALA-TPSAPYGFA----LLNCGKN 714
Query: 817 AVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRV 876
+ I W P + GG +LGY +++ W VN+ PI C V L E YEFR
Sbjct: 715 EMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRA 774
Query: 877 IAVNKAGPGQPSVPSSSVVAKDPVKP-PGLVQDLHVSDSSNSSISLAWREPAE--GDPPS 933
A N AG G+ S PSS K+ P PG D+ S+ +S+ L W P P +
Sbjct: 775 RAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVT 834
Query: 934 GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV 993
GY + + E +++W T PISGT V L + Y F+++A+N AG+G+P V
Sbjct: 835 GYHVSFQEEGSEQWKPVTPGPISGTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPV 894
Query: 994 RAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVI---WQKD--GVPTKGR 1048
P A + ++ + I+ AF PD W KD G R
Sbjct: 895 LLEDKPGAHEIEVGVDEEGF----------IYLAFEAPEAPDSSEFQWSKDYKGPLDPQR 944
Query: 1049 ETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLR-LFEE 1107
I N S+ ++ D G Y +++ +A DI L+ L E
Sbjct: 945 VKIEDKVNKSKVILKEPGLEDLGTYSVIVT----DADEDISASHTLTEEELEKLKKLSHE 1000
Query: 1108 VPNTVTLT---WNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRK 1164
+ N V WN D+ E GE + S A +F+NK + P RK
Sbjct: 1001 IRNPVIKLISGWNI--DILERGEVRLWLEVEKLSPAA---ELHLIFNNKEIFSS--PNRK 1053
Query: 1165 YYF-------RVVARN-----------EIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEK 1206
F V+ +N ++ D + + L++ D D + ++
Sbjct: 1054 INFDREKGLVEVIIQNLSEEDKGSYTAQLQDGKAKNQITLTLVDDDF--DKLLRKADAKR 1111
Query: 1207 KDWRH--APRFVTPLKPHTVLRGQDCT--MTCAFLGNPRPTVTLYKGDVNITANSKFWYN 1262
+DW+ P F PL+ +DC +TC + T ++ Y+
Sbjct: 1112 RDWKRKQGPYFERPLQWKVT---EDCQVQLTCKVTNTKKET--RFQWFFQRAEMPDGQYD 1166
Query: 1263 STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLT 1301
+G L I + KD G Y +V ++ G+D + LT
Sbjct: 1167 PETGTGLLCIEELSKKDKGIYRAMVSDDRGEDDTILDLT 1205
Score = 54.3 bits (129), Expect = 8e-07
Identities = 99/489 (20%), Positives = 181/489 (37%), Gaps = 87/489 (17%)
Query: 292 KYMLVISNVNMNDAGIYSLSV--GDKRMSAELTVLDEPLKFLGEMKP------------- 336
K +++ + D G YS+ V D+ +SA T+ +E L+ L ++
Sbjct: 953 KSKVILKEPGLEDLGTYSVIVTDADEDISASHTLTEEELEKLKKLSHEIRNPVIKLISGW 1012
Query: 337 -VKVTERQTAVFEIRLSKKEP--NFVWKFNGKELKRDDKYEITVS-EDGLTHTLKIKDAR 392
+ + ER + + K P FN KE+ +I E GL + I++
Sbjct: 1013 NIDILERGEVRLWLEVEKLSPAAELHLIFNNKEIFSSPNRKINFDREKGLVEVI-IQNLS 1071
Query: 393 LSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERS------------------ 434
D G ++A+ + K Q+T+ + F L+ K R
Sbjct: 1072 EEDKGSYTAQLQDGKAKNQITLTLVDDDFDKLLRKADAKRRDWKRKQGPYFERPLQWKVT 1131
Query: 435 ---RACLECELTS--KDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYT 489
+ L C++T+ K+ +W + G + E L IE+ D G Y
Sbjct: 1132 EDCQVQLTCKVTNTKKETRFQWFFQRAEMPDG---QYDPETGTGLLCIEELSKKDKGIYR 1188
Query: 490 VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL------------CVVL 537
+ D + T + + L + + + + A + +P ++
Sbjct: 1189 AMVSDDRGEDD---TILDLTGDALDAIFTELGRIGALSATPLKIQGTEEGIRIFSKVKYY 1245
Query: 538 NDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEH--EGKYTF--------RA 587
N E ++ W K + G +I + ++ + P+ +GKYT R
Sbjct: 1246 NVEYMKTTWFHKDKRLES--GDRIRTGTTLDEIWLHILDPKDSDKGKYTLEIAAGKEVRQ 1303
Query: 588 KGTESEASVF---IADPPTIDP-SVLEALAAHAI-------TVKVGHTAHIKVPFRGKPL 636
T+ F +A+ + +++E A + T+ T + G P
Sbjct: 1304 LSTDLSGQAFEDAMAEHQRLKTLAIIEKNRAKVVRGLPDVATIMEDKTLCLTCIVSGDPT 1363
Query: 637 PKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLS 696
P+++W K+ VT +R ME + +TI EDSG + +KN +GS T + +S
Sbjct: 1364 PEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFVKNKYGSETGQVTIS 1423
Query: 697 VL---DRPK 702
V D PK
Sbjct: 1424 VFKHGDEPK 1432
Score = 53.1 bits (126), Expect = 2e-06
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 4/126 (3%)
Query: 1181 LDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNP 1240
L R W + + ++ + K + + P F PL+ H V +TC +P
Sbjct: 122 LRQRRDWKTLRRRTEEKVQEAKELRELCYGRGPWFWIPLRSHAVWEHTTVLLTCTVQASP 181
Query: 1241 RPTVTLYKGDVNITAN----SKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRS 1296
P VT YK D I K+ + G+ +L I C ++DS Y+V V+N G+ S
Sbjct: 182 PPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYTVRVKNAHGQASS 241
Query: 1297 SCTLTV 1302
+ V
Sbjct: 242 FAKVLV 247
Score = 47.0 bits (110), Expect = 1e-04
Identities = 78/328 (23%), Positives = 122/328 (37%), Gaps = 70/328 (21%)
Query: 214 DFRGLLRKL----KEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWI 269
DF LLRK ++ K+K + +PL+ K T+ D V C + + W
Sbjct: 1099 DFDKLLRKADAKRRDWKRK---QGPYFERPLQWKVTE-DCQVQLTCKVTNTKKETRFQWF 1154
Query: 270 KGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLD---- 325
R + G+YD + GT +L I ++ D GIY V D R + T+LD
Sbjct: 1155 FQ----RAEMPDGQYD-PETGTG-LLCIEELSKKDKGIYRAMVSDDRGEDD-TILDLTGD 1207
Query: 326 -----------------EPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELK 368
PLK G + +++ + + + K W K L+
Sbjct: 1208 ALDAIFTELGRIGALSATPLKIQGTEEGIRIFSK-VKYYNVEYMKT----TWFHKDKRLE 1262
Query: 369 RDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVS----- 423
D+ + D + L I D + SD G+++ E + QL+ D F
Sbjct: 1263 SGDRIRTGTTLDEIW--LHILDPKDSDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEH 1320
Query: 424 -NLKNVRVKERSRA------------------CLECELTSKDVT--LRWKKDGQLLMHGT 462
LK + + E++RA CL C + S D T + W K+ Q +
Sbjct: 1321 QRLKTLAIIEKNRAKVVRGLPDVATIMEDKTLCLTC-IVSGDPTPEISWLKNDQPVTFLD 1379
Query: 463 KYSMNHEGKRAELIIEDAQLSDGGEYTV 490
+Y M G + IE D G Y V
Sbjct: 1380 RYRMEVRGTEVTITIEKVNSEDSGRYGV 1407
Score = 47.0 bits (110), Expect = 1e-04
Identities = 22/86 (25%), Positives = 41/86 (47%)
Query: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGD 1282
T++ + +TC G+P P ++ K D +T ++ T+ I +DSG
Sbjct: 1345 TIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGR 1404
Query: 1283 YSVLVENELGKDRSSCTLTVYDKDDK 1308
Y V V+N+ G + T++V+ D+
Sbjct: 1405 YGVFVKNKYGSETGQVTISVFKHGDE 1430
Score = 44.3 bits (103), Expect = 8e-04
Identities = 39/156 (25%), Positives = 73/156 (46%), Gaps = 15/156 (9%)
Query: 184 KVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDK 243
++A KE+ ++ + + + FE E+ ++LK + +E ++++ L D
Sbjct: 1294 EIAAGKEVRQLSTDLSGQAFEDAMAEH---------QRLKTLAI-IEKNRAKVVRGLPDV 1343
Query: 244 ETKV-DTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNM 302
T + D T+ CI+ DP ++ W+K +P+ L +Y ++ GT+ + I VN
Sbjct: 1344 ATIMEDKTLCLTCIVS-GDPTPEISWLKNDQPVTF---LDRYRMEVRGTEVTITIEKVNS 1399
Query: 303 NDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVK 338
D+G Y + V +K S V K E K +K
Sbjct: 1400 EDSGRYGVFVKNKYGSETGQVTISVFKHGDEPKELK 1435
Score = 38.1 bits (87), Expect = 0.056
Identities = 42/181 (23%), Positives = 75/181 (41%), Gaps = 23/181 (12%)
Query: 379 EDGLTHTLKIKDARLSDSG--------EFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRV 430
ED T+T+++K+A S +AG + + + ++F S LK V
Sbjct: 223 EDSATYTVRVKNAHGQASSFAKVLVRTYLGKDAGFDSEIFKRSTFGPSVEFTSVLKPVFA 282
Query: 431 KERSRACLECELTSKDV----TLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGG 486
+E+ L C L S+DV +++W +DG LL + + + ++A L + D G
Sbjct: 283 REKEPFSLSC-LFSEDVLDAESIQWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEG 341
Query: 487 EYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGV 545
Y V P E + V+ ++ A GSP + C+ +N + +
Sbjct: 342 LYMVRVPSPFGPRE---------QSTYVLVRDAEAENPGAPGSPLNVRCLDVNRDCLILT 392
Query: 546 W 546
W
Sbjct: 393 W 393
Score = 35.8 bits (81), Expect = 0.28
Identities = 20/84 (23%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 1022 LCIHAAFSGSPPPDVIWQKDGVPTK--GRETITKSKNHSQFLINSTKRSDSGVYRILLQN 1079
LC+ SG P P++ W K+ P R + I DSG Y + ++N
Sbjct: 1352 LCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFVKN 1411
Query: 1080 EFGEARYDIHVRVADFPRPPTNLR 1103
++G + + V P L+
Sbjct: 1412 KYGSETGQVTISVFKHGDEPKELK 1435
Score = 34.7 bits (78), Expect = 0.62
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 6/84 (7%)
Query: 612 LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEE----ERVSMERGEDQALLTI 667
L +HA+ T + + P P+VTWYK+ + + + L I
Sbjct: 160 LRSHAVWEHT--TVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEI 217
Query: 668 SNCVREDSGLILLKLKNDHGSATA 691
C EDS +++KN HG A++
Sbjct: 218 RRCAIEDSATYTVRVKNAHGQASS 241
Score = 31.6 bits (70), Expect = 5.3
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 7/81 (8%)
Query: 1010 LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP------TKGRETITKSKNHSQFLIN 1063
L+SH V T L + SPPP V W K+ G+ IT + I
Sbjct: 160 LRSHAVWEHTTVL-LTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIR 218
Query: 1064 STKRSDSGVYRILLQNEFGEA 1084
DS Y + ++N G+A
Sbjct: 219 RCAIEDSATYTVRVKNAHGQA 239
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 145 bits (366), Expect = 3e-34
Identities = 112/431 (25%), Positives = 193/431 (44%), Gaps = 16/431 (3%)
Query: 269 IKGTEPL-RIQYSLGKYDVKQMGTKYMLVISNVNMNDAG-IYSLSVGDKRMSAELTVLDE 326
+K EP +++ +Y ++Q G ++ L++ V D+G + S + SA LT+ +
Sbjct: 654 LKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCPGVQDSAALTIQES 713
Query: 327 PLKFLGEMKPVKVT--ERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTH 384
P+ L V +T + V LS+ + W +G++++ + + V DG H
Sbjct: 714 PVHILSPQDRVSLTFTTSERVVLTCELSRVDFPATWYKDGQKVEESEL--LVVKMDGRKH 771
Query: 385 TLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRAC--LECEL 442
L + +A++ DSGEF + +T+ P+ V ++V V + C L CE+
Sbjct: 772 RLILPEAKVQDSGEFECRTEGVSAFFGVTVQDPPVHIVDPREHVFVHAITSECVMLACEV 831
Query: 443 TSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYY 502
+D +RW KDGQ + + +EG L++ Q SDGGE+ VA GD Y+
Sbjct: 832 DREDAPVRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVA---GDECAYF 888
Query: 503 STAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIV 562
+ I V + SG V A L L E W KDG+E+ + P + +
Sbjct: 889 TVTITDVSSWI-VYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQ 947
Query: 563 KQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVG 622
K+ V +L+ P++ E G+Y + +V + +PP + + A+T++
Sbjct: 948 KEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIAVTLE-- 1005
Query: 623 HTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKL 682
+ + P V WYKDG+EV E E + +ER + L + ED G +
Sbjct: 1006 -CVVLMCELSREDAP-VRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDA 1063
Query: 683 KNDHGSATATL 693
+D T T+
Sbjct: 1064 GDDSAFFTVTV 1074
Score = 117 bits (294), Expect = 6e-26
Identities = 148/647 (22%), Positives = 249/647 (38%), Gaps = 69/647 (10%)
Query: 68 EFVEKPQPVTAPEGDKAVFRARVQGNAK--PHIS-------WKRESGIPIKESAKIFYDS 118
+ E P V APE + R+ G+ + H+S W ++ G + ++ +
Sbjct: 1261 QVAEPPVRVVAPEAAQTRVRSTPGGDLELVVHLSGPGGPVRWYKD-GERLASQGRVQLEQ 1319
Query: 119 INKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVS-------------LLVTEGQEKMD 165
VL+++ S D+ Y C A D + +V L V EG +
Sbjct: 1320 AGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKLVSELTPLTVHEGDDATF 1379
Query: 166 FKKM---------LKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFR 216
++ L+ A P + + N + L D V + G T
Sbjct: 1380 RCEVSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRAGSTATS 1439
Query: 217 GLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNV----KMIWIKGT 272
L ++ E+ +R L+ + +E + D +E++ V + W++G
Sbjct: 1440 ARLHV-----RETELLFLRRLQDVRAEEGQ-------DVCLEVETGRVGAAGAVRWVRGG 1487
Query: 273 EPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLG 332
+PL L + Q G + L I V + D G Y R A L+V L+ L
Sbjct: 1488 QPLPHDSRLS---MAQDGHIHRLFIHGVILADQGTYGCESHHDRTLARLSVRPRQLRVLR 1544
Query: 333 EMKPVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDAR 392
++ V ++E +A F++ LS++ W G +L K I DG H L +
Sbjct: 1545 PLEDVTISEGGSATFQLELSQEGVTGEWARGGVQLYPGPKCHI--HSDGHRHRLVLNGLG 1602
Query: 393 LSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWK 452
L+DSG S A +L A+L + +P+ V ++ V E A ECEL+ + W+
Sbjct: 1603 LADSGCVSFTADSLRCAARLIVREVPVTIVRGPHDLEVTEGDTATFECELSQALADVTWE 1662
Query: 453 KDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEER 512
KDG L + + G R L + SD G Y+ T +TV ER
Sbjct: 1663 KDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTYSCAV-----GTARAGPVRLTVRER 1717
Query: 513 LATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIF 572
V S + V A G A +++ + G W G+ + ++I ++G H L+
Sbjct: 1718 TVAVLSELRSVSAREGDGATFECTVSEVETTGRWELGGRPLRPGARVRIRQEGKKHILVL 1777
Query: 573 PSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAH---AITVKVGHTAHIKV 629
+ E G+ F+A +S A + + P + H TV VG A ++V
Sbjct: 1778 SELRAEDAGEVRFQAGPAQSLALLEVEALPL-------QMCRHPPREKTVLVGRRAVLEV 1830
Query: 630 PFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ V W ++G E+ ++ M L I + ED G
Sbjct: 1831 TV-SRSGGHVCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQG 1876
Score = 117 bits (292), Expect = 1e-25
Identities = 93/361 (25%), Positives = 160/361 (44%), Gaps = 15/361 (4%)
Query: 229 VEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQ 288
V +R+L+PLED + F +EL V W +G L Y K +
Sbjct: 1535 VRPRQLRVLRPLEDVTISEGGSATFQ--LELSQEGVTGEWARGGVQL---YPGPKCHIHS 1589
Query: 289 MGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFE 348
G ++ LV++ + + D+G S + R +A L V + P+ + ++VTE TA FE
Sbjct: 1590 DGHRHRLVLNGLGLADSGCVSFTADSLRCAARLIVREVPVTIVRGPHDLEVTEGDTATFE 1649
Query: 349 IRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL-V 407
LS+ + W+ +G L + + G L+++ SD+G +S G
Sbjct: 1650 CELSQALADVTWEKDGNALTPSPRLRLQAL--GTRRLLQLRRCGPSDAGTYSCAVGTARA 1707
Query: 408 QKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMN 467
+LT+ + +S L++V +E A EC ++ + T RW+ G+ L G + +
Sbjct: 1708 GPVRLTVRERTVAVLSELRSVSAREGDGATFECTVSEVETTGRWELGGRPLRPGARVRIR 1767
Query: 468 HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEER-LATVKSGMSDVHAA 526
EGK+ L++ + + D GE V Q G P + S A++ VE L + +
Sbjct: 1768 QEGKKHILVLSELRAEDAGE---VRFQAG-PAQ--SLALLEVEALPLQMCRHPPREKTVL 1821
Query: 527 TGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR 586
G A L V ++ WL++G E+ ++ G H L+ + PE +G Y +
Sbjct: 1822 VGRRAVLEVTVSRSGGHVCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQ 1881
Query: 587 A 587
A
Sbjct: 1882 A 1882
Score = 100 bits (250), Expect = 7e-21
Identities = 133/641 (20%), Positives = 244/641 (38%), Gaps = 51/641 (7%)
Query: 229 VEVEAIRILKPLEDKETKVDTT--VVFDCIMELKDPNVKMIWIK-GTEPLRIQYSLGKYD 285
V+ + I+ P E T+ V+ C ++ +D V+ W K G E + +
Sbjct: 801 VQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAPVR--WYKDGQEVEESDFVV---- 854
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEP--LKFLGEMKPVKVTERQ 343
++ G LV+ +D G + GD+ +T+ D + + V +
Sbjct: 855 LENEGPHRRLVLPATQPSDGGEFQCVAGDECAYFTVTITDVSSWIVYPSGKVYVAAVRLE 914
Query: 344 TAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA 403
V L + W +G+E+ + + ++ L + +L DSGE+ E
Sbjct: 915 RVVLTCELCRPWAEVRWTKDGEEVVESPA--LLLQKEDTVRRLVLPAVQLEDSGEYLCEI 972
Query: 404 GNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRAC--LECELTSKDVTLRWKKDGQLLMHG 461
+ +T+ P++ + V + + C L CEL+ +D +RW KDG +
Sbjct: 973 DDESASFTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAPVRWYKDGLEVEES 1032
Query: 462 TKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMS 521
+ +G R L++ AQ DGGE+ A GD + +++ + ER+ +
Sbjct: 1033 EALVLERDGPRCRLVLPAAQPEDGGEFVCDA---GDDSAFFTVTVTAPPERIVHPAARSL 1089
Query: 522 DVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEG 581
D+H EL + + W KDG E+ +Q+ +G L P PE G
Sbjct: 1090 DLHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAG 1149
Query: 582 KYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW 641
+Y + +V +A+PP + LE + + V G + P V W
Sbjct: 1150 EYVCETRHEAITFNVILAEPP-VQFLALETTPS-PLCVAPGEPVVLSCELSRAGAP-VVW 1206
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP 701
+G V E E + + + +L I +GL + G+ + + + V + P
Sbjct: 1207 SHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPP 1266
Query: 702 --------------KPPQGRVEF-LELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKK 746
P G +E + LSG ++W +G R +Q V+ G +
Sbjct: 1267 VRVVAPEAAQTRVRSTPGGDLELVVHLSGPGGPVRW---YKDGERLASQGRVQLEQAGAR 1323
Query: 747 SWIKI-GEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFA 805
+++ G G + + ++ RI V+ V +PL + V P+
Sbjct: 1324 QVLRVQGARSGDAGEYLCDAPQDS-----RIFLVS---VEEPLLVKLVSELTPLTVHEGD 1375
Query: 806 SQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSN 846
+V+ +TW ++G G VE + GS+
Sbjct: 1376 DATFRCEVSPPDADVTW---LRNGAVVTPGPQVEMAQNGSS 1413
Score = 98.2 bits (243), Expect = 5e-20
Identities = 73/268 (27%), Positives = 118/268 (44%), Gaps = 9/268 (3%)
Query: 234 IRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKY 293
+ I++ D E T F+C EL + W K L L ++ +GT+
Sbjct: 1629 VTIVRGPHDLEVTEGDTATFEC--ELSQALADVTWEKDGNALTPSPRLR---LQALGTRR 1683
Query: 294 MLVISNVNMNDAGIYSLSVGDKRMS-AELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLS 352
+L + +DAG YS +VG R LTV + + L E++ V E A FE +S
Sbjct: 1684 LLQLRRCGPSDAGTYSCAVGTARAGPVRLTVRERTVAVLSELRSVSAREGDGATFECTVS 1743
Query: 353 KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQL 412
+ E W+ G+ L+ + + + ++G H L + + R D+GE +AG A L
Sbjct: 1744 EVETTGRWELGGRPLRPGAR--VRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLALL 1801
Query: 413 TIDRIPIKFVSNLKNVR-VKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGK 471
++ +P++ + + V RA LE ++ + W ++G L G KY M G
Sbjct: 1802 EVEALPLQMCRHPPREKTVLVGRRAVLEVTVSRSGGHVCWLREGAELCPGDKYEMRSHGP 1861
Query: 472 RAELIIEDAQLSDGGEYTVVAMQDGDPT 499
L+I D + D G Y A QD T
Sbjct: 1862 THSLVIHDVRPEDQGTYCCQAGQDSTHT 1889
Score = 89.0 bits (219), Expect = 3e-17
Identities = 114/518 (22%), Positives = 210/518 (40%), Gaps = 33/518 (6%)
Query: 234 IRILKPLEDKETKVDTT---VVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMG 290
+RI+ P D+ T + T VV C + +D V+ W K + L ++ S +++ G
Sbjct: 988 VRIIYP-RDEVTLIAVTLECVVLMCELSREDAPVR--WYK--DGLEVEESEALV-LERDG 1041
Query: 291 TKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEM-KPVKVTERQTAVFEI 349
+ LV+ D G + GD +TV P + + + + + E+
Sbjct: 1042 PRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPAARSLDLHFGAPGRVEL 1101
Query: 350 R--LSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
R ++ W +G E++ D ++ +G T TL + A+ D+GE+ E +
Sbjct: 1102 RCEVAPAGSQVRWYKDGLEVEASDALQL--GAEGPTRTLTLPHAQPEDAGEYVCETRHEA 1159
Query: 408 QKAQLTIDRIPIKFVS---NLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKY 464
+ + P++F++ + V L CEL+ + W +G+ + G
Sbjct: 1160 ITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAPVVWSHNGRPVQEGEGL 1219
Query: 465 SMNHEGKRAELIIEDAQLSDGGEYTVVA-MQDGDPTEYYSTAIVTVEERLATVKSGMSDV 523
++ EG R L I+ A + G YT + G P+ ++ + R+ ++ + V
Sbjct: 1220 ELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRV 1279
Query: 524 HAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKY 583
+ G EL V L+ W KDG+ + +Q+ + GA L G+Y
Sbjct: 1280 RSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEY 1339
Query: 584 TFRAKGTESEASVFIADPPTIDPSVLEALAAHA--ITVKVGHTAHIKVPFRGKPLPKVTW 641
A ++ +F+ +++ +L L + +TV G A + P VTW
Sbjct: 1340 LCDAP---QDSRIFLV---SVEEPLLVKLVSELTPLTVHEGDDATFRCEV-SPPDADVTW 1392
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA------TATLHL 695
++G VT +V M + +LT+ C D+G + L+ + SA T L L
Sbjct: 1393 LRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRAGSTATSARLHVRETELLFL 1452
Query: 696 SVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPV 733
L + +G+ LE+ V GG+P+
Sbjct: 1453 RRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPL 1490
Score = 83.2 bits (204), Expect = 2e-15
Identities = 149/673 (22%), Positives = 255/673 (37%), Gaps = 103/673 (15%)
Query: 71 EKPQPVTAP-----------EGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSI 119
E P PV P EG A FR V G +P I W E + + ++ Y
Sbjct: 239 EAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDR 298
Query: 120 NKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPK 179
+ VLK+ + D Y C A N + V L V E + + +
Sbjct: 299 DGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIA 358
Query: 180 KKQKKVANEK----EMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLK---------EMK 226
+ KV N + E +P + +E++ E G T R ++ +LK EM+
Sbjct: 359 VLECKVPNSRIPTAWFREDQRLLPCRKYEQI--EEG-TVRRLIIHRLKADDDGIYLCEMR 415
Query: 227 KKVEVEAIRILKP--LEDKETKVDTTVVFDCIM--ELKDPNVKMIWIKGTEPLRIQYSLG 282
+V A +K L+ K+D + ++ E + V+ W + E L +
Sbjct: 416 GRVRTVANVTVKGPILKRLPRKLDVLEGENAVLLVETLEAGVEGRWSRDGEELPVICQ-- 473
Query: 283 KYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTER 342
G + LV+ V DAG + S+G+ R + L V + +K P+
Sbjct: 474 ----SSSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRV--KCVKHSPPGPPILAEMF 527
Query: 343 QTAVFEIRLSKKEPN------FVWKFNGKELKRDDKYE-ITVSEDGLTHT---------- 385
+ + L+ K P F+++ +E+ +D + ++ + G
Sbjct: 528 KGHKNTVLLTWKPPEPAPETPFIYRLERQEVGSEDWIQCFSIEKAGAVEVPGDCVPSEGD 587
Query: 386 LKIKDARLSDSGE-----FSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLEC 440
+ + +S G F A +LV A+L V+ L++V+V + A
Sbjct: 588 YRFRICTVSGHGRSPHVVFHGSA-HLVPTARL---------VAGLEDVQVYDGEDAVFSL 637
Query: 441 ELTSKDVTLRW----------KKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGE--- 487
+L S + W + +GQ+ +Y + +G + LI+ + D G
Sbjct: 638 DL-STIIQGTWFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVG 696
Query: 488 YTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHA--ATGSPAELCVVLNDEKVEGV 545
++ +QD +A +T++E + S V T L L+
Sbjct: 697 FSCPGVQD--------SAALTIQESPVHILSPQDRVSLTFTTSERVVLTCELSRVDFPAT 748
Query: 546 WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPT-- 603
W KDG+++ + + + G H+LI P + G++ R +G + V + DPP
Sbjct: 749 WYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEGVSAFFGVTVQDPPVHI 808
Query: 604 IDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQA 663
+DP E + HAIT + A +V P V WYKDG EV E + V +E
Sbjct: 809 VDPR--EHVFVHAITSECVMLA-CEVDREDAP---VRWYKDGQEVEESDFVVLENEGPHR 862
Query: 664 LLTISNCVREDSG 676
L + D G
Sbjct: 863 RLVLPATQPSDGG 875
Score = 70.9 bits (172), Expect = 8e-12
Identities = 135/593 (22%), Positives = 229/593 (38%), Gaps = 86/593 (14%)
Query: 255 CIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL---- 310
C++ L +P ++W KG + L L G ++ L+++ DAG+Y
Sbjct: 33 CVV-LGEPPPVVVWEKGGQQLAASERLS---FPADGAEHGLLLTAALPTDAGVYVCRARN 88
Query: 311 SVGDKRMSAELTVLDEPLKF--------------LGEMKPVKVTERQTAVF----EIRLS 352
+ G+ +A +TVL+ P GE PV +T ++ E+ L+
Sbjct: 89 AAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLT 148
Query: 353 KK-----EPNFVWKFNGKELKRDDKYEITV-------SEDG--LTHTLKIKDARLSDSGE 398
+ EP W+ +G L D+ ++ + +EDG + L+I ARL DSG
Sbjct: 149 CRAGGLPEPTLYWEKDGMAL--DEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGV 206
Query: 399 F---------SAEAGNLVQKAQ------LTIDRIPIKFVSNL----KNVRVKERSRACLE 439
+ A+AG L+Q Q D P V L K V E A
Sbjct: 207 YVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGKHAKFR 266
Query: 440 CELTSK-DVTLRWKKDGQLLMHGTKYSMNHEGKRAELI-IEDAQLSDGGEYTVVAMQDGD 497
C + K + + W +G+ L+ + M + ++ + Q D G Y A
Sbjct: 267 CYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAG 326
Query: 498 PTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLP 557
T S + V+E + DV A L + + ++ W ++ + +
Sbjct: 327 QT--LSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPTAWFREDQRLLPCR 384
Query: 558 GMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKG-TESEASVFIADPPTIDPSVLEALAAHA 616
+ +++G V +LI + + +G Y +G + A+V + P +L+ L
Sbjct: 385 KYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVANVTVKGP------ILKRL-PRK 437
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ V G A + V + + W +DG E+ + L + RED+G
Sbjct: 438 LDVLEGENAVLLVETLEAGV-EGRWSRDGEELPV---ICQSSSGHMHALVLPGVTREDAG 493
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQF 736
+ L N + T V P P E + + V + WK P+ P T F
Sbjct: 494 EVTFSLGNSR-TTTLLRVKCVKHSPPGPPILAEMFKGHKNTVLLTWKPPEP---APETPF 549
Query: 737 I--VERRAVGKKSWIKIGEVD--GKVTNFSTNKVEEGKAYQFRILAVNSEGVS 785
I +ER+ VG + WI+ ++ G V EG Y+FRI V+ G S
Sbjct: 550 IYRLERQEVGSEDWIQCFSIEKAGAVEVPGDCVPSEGD-YRFRICTVSGHGRS 601
Score = 70.5 bits (171), Expect = 1e-11
Identities = 87/441 (19%), Positives = 176/441 (39%), Gaps = 35/441 (7%)
Query: 251 VVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSL 310
VV C EL ++W P++ L ++ G + +L I AG+Y+
Sbjct: 1191 VVLSC--ELSRAGAPVVWSHNGRPVQEGEGL---ELHAEGPRRVLCIQAAGPAHAGLYTC 1245
Query: 311 ----SVGDKRMSAELTVLDEPLKFLGE---MKPVKVTERQTAVFEIRLSKKEPNFVWKFN 363
+ G +S + V + P++ + V+ T + LS W +
Sbjct: 1246 QSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELVVHLSGPGGPVRWYKD 1305
Query: 364 GKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDR-IPIKFV 422
G+ L + ++ + G L+++ AR D+GE+ +A + ++++ + +K V
Sbjct: 1306 GERLASQGRVQL--EQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKLV 1363
Query: 423 SNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQL 482
S L + V E A CE++ D + W ++G ++ G + M G L + QL
Sbjct: 1364 SELTPLTVHEGDDATFRCEVSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQL 1423
Query: 483 SDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKV 542
D G T+ A ++A + V E + DV A G ++C+ + +V
Sbjct: 1424 GDAGTVTLRAGSTA------TSARLHVRETELLFLRRLQDVRAEEGQ--DVCLEVETGRV 1475
Query: 543 EGV----WLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFI 598
W++ G+ + + + + G +H+L + +G Y G ES +
Sbjct: 1476 GAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTY-----GCESHHDRTL 1530
Query: 599 ADPPTIDPSVLEAL-AAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSME 657
A ++ P L L +T+ G +A ++ + + W + G+++ + +
Sbjct: 1531 A-RLSVRPRQLRVLRPLEDVTISEGGSATFQLELSQEGVTG-EWARGGVQLYPGPKCHIH 1588
Query: 658 RGEDQALLTISNCVREDSGLI 678
+ L ++ DSG +
Sbjct: 1589 SDGHRHRLVLNGLGLADSGCV 1609
Score = 62.8 bits (151), Expect = 2e-09
Identities = 51/188 (27%), Positives = 79/188 (42%), Gaps = 8/188 (4%)
Query: 229 VEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQ 288
V + +L L + F+C + + + W G PLR + ++Q
Sbjct: 1714 VRERTVAVLSELRSVSAREGDGATFECTVSEVETTGR--WELGGRPLRPG---ARVRIRQ 1768
Query: 289 MGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVK-VTERQTAVF 347
G K++LV+S + DAG G + A L V PL+ K V + AV
Sbjct: 1769 EGKKHILVLSELRAEDAGEVRFQAGPAQSLALLEVEALPLQMCRHPPREKTVLVGRRAVL 1828
Query: 348 EIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
E+ +S+ + W G EL DKYE+ G TH+L I D R D G + +AG
Sbjct: 1829 EVTVSRSGGHVCWLREGAELCPGDKYEMR--SHGPTHSLVIHDVRPEDQGTYCCQAGQDS 1886
Query: 408 QKAQLTID 415
+L ++
Sbjct: 1887 THTRLLVE 1894
Score = 53.1 bits (126), Expect = 2e-06
Identities = 75/328 (22%), Positives = 115/328 (35%), Gaps = 50/328 (15%)
Query: 418 PIKFVSNLKNVRVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEGKRAELI 476
P F+ + VRV + A L+C + + + W+K GQ L + S +G L+
Sbjct: 11 PPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLL 70
Query: 477 IEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEE------RLATVKSGMSDVHAATGSP 530
+ A +D G Y A E Y+ A VTV E L + + + G+P
Sbjct: 71 LTAALPTDAGVYVCRARNAAG--EAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAP 128
Query: 531 AELCVVLNDEKVEGV-----------------WLKDGKEITDL---------PGMQIVKQ 564
L + + G W KDG + ++ PG
Sbjct: 129 VFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGP 188
Query: 565 GAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFI------------ADPPTIDPSVLEAL 612
GA L + G Y A+ A ADP V+E L
Sbjct: 189 GASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPL 248
Query: 613 --AAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQA-LLTISN 669
A V G A + GKP P++ W+ +G + + R M R D +L +
Sbjct: 249 KCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLY 308
Query: 670 CVREDSGLILLKLKNDHGSATATLHLSV 697
C +D GL + +N G + + L V
Sbjct: 309 CQAKDRGLYVCAARNSAGQTLSAVQLHV 336
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/85 (28%), Positives = 42/85 (49%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
+ V G A +K G+P P V W K G ++ ER+S + L ++ + D+G
Sbjct: 21 VRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAG 80
Query: 677 LILLKLKNDHGSATATLHLSVLDRP 701
+ + + +N G A A ++VL+ P
Sbjct: 81 VYVCRARNAAGEAYAAAAVTVLEPP 105
Score = 42.0 bits (97), Expect = 0.004
Identities = 81/335 (24%), Positives = 118/335 (35%), Gaps = 39/335 (11%)
Query: 998 PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNH 1057
PP +F R+ S G + G PPP V+W+K G E ++ +
Sbjct: 11 PPCFLRFPRPVRVVS------GAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADG 64
Query: 1058 SQ--FLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEE-VPN---- 1110
++ L+ + +D+GVY +N GEA V V + P L+ E +P+
Sbjct: 65 AEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSG 124
Query: 1111 ---TVTLTWNHSPDVQEDGEAHYIIMKRDASTATWY-----TAAERVFSNKYTVTGLLPG 1162
V LT S V E T Y A + V+ + + L PG
Sbjct: 125 EGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSH--FALQPG 182
Query: 1163 R-------KYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEK--KDWRHAP 1213
R R++A + DS Q L +P E D AP
Sbjct: 183 RAEDGPGASLALRILAA-RLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAP 241
Query: 1214 R-FVTPLK--PHT--VLRGQDCTMTCAFLGNPRPTVTL-YKGDVNITANSKFWYNSTSGV 1267
V PLK P T V G+ C +G P P + ++G + + Y G
Sbjct: 242 APVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGG 301
Query: 1268 CTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
L + C KD G Y N G+ S+ L V
Sbjct: 302 FVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHV 336
Score = 39.7 bits (91), Expect = 0.019
Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 65 SVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV 124
S P F+ P+PV G +A + V G P + W++ G + S ++ + + EH
Sbjct: 10 SPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEK-GGQQLAASERLSFPADGAEHG 68
Query: 125 LKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTE 159
L L D+ Y C A N +A ++ V E
Sbjct: 69 LLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLE 103
Score = 39.3 bits (90), Expect = 0.025
Identities = 22/92 (23%), Positives = 40/92 (43%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P F+ +P V+ G + + C LG P P V KG + A+ + + + L++
Sbjct: 12 PCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLL 71
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
D+G Y N G+ ++ +TV +
Sbjct: 72 TAALPTDAGVYVCRARNAAGEAYAAAAVTVLE 103
Score = 31.2 bits (69), Expect = 6.9
Identities = 29/104 (27%), Positives = 40/104 (38%), Gaps = 15/104 (14%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNS-------- 1263
AP F+T + VLRG + +TC G P PT+ K + A + W +S
Sbjct: 127 APVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGM---ALDEVWDSSHFALQPGR 183
Query: 1264 ----TSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVY 1303
L I L DSG Y N G ++ L V+
Sbjct: 184 AEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVH 227
>gi|194018539 myosin binding protein H-like [Homo sapiens]
Length = 354
Score = 127 bits (320), Expect = 5e-29
Identities = 92/327 (28%), Positives = 140/327 (42%), Gaps = 17/327 (5%)
Query: 982 GVGEPVELDKGVRAMPP-PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK 1040
G G P + +PP PK L L+ + + G + + F G P P IW
Sbjct: 35 GAGSPTP-----QLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH 89
Query: 1041 DGVPTKGRE-TITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPP 1099
DG R ++ + S I +R+DSG Y++ +Q EA I + V + P PP
Sbjct: 90 DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
Query: 1100 TNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGL 1159
+++L + + TL W D Y + K D + W+T E V+ L
Sbjct: 150 QSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDL 209
Query: 1160 LPGRKYYFRVVARNEIGDSEPLDSRDTWLINKD--QIQDLSA--KLKPYEKKDWRHAPRF 1215
+ G Y FRV A N+ G SE T I D IQ + K K + ++D+ AP+F
Sbjct: 210 IIGNSYAFRVFAENQCGLSE------TAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
Query: 1216 VTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
PL T + G + + C +PRP + K ++I N K+ + G+C+L I
Sbjct: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
Query: 1276 TLKDSGDYSVLVENELGKDRSSCTLTV 1302
D G Y+ N LG+ C + V
Sbjct: 324 GPFDGGIYTCKAVNPLGEASVDCRVDV 350
Score = 95.5 bits (236), Expect = 3e-19
Identities = 60/212 (28%), Positives = 105/212 (49%), Gaps = 13/212 (6%)
Query: 620 KVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLIL 679
KVG T ++ +PF+GKP P+ W DG + + RVS+ GE ++L I R DSG
Sbjct: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
Query: 680 LKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVE 739
L+++ ATAT+ + V++RP PPQ ++ +++ G ++W P+D G + + V+
Sbjct: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
Query: 740 RRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSD--PLETE------ 791
+ W + E + T+ + + G +Y FR+ A N G+S+ P+ T+
Sbjct: 184 KADTKSGLWFTVLEHYHR-TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQK 242
Query: 792 --EVFAGNPIEPPGFASQPQVTDVTKEAVTIT 821
V+ F+ P+ T + T+T
Sbjct: 243 AATVYKTKGFAQRDFSEAPKFTQPLADCTTVT 274
Score = 52.8 bits (125), Expect = 2e-06
Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 9/135 (6%)
Query: 749 IKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQP 808
++ GE D + + + G+ YQ R+ E + T ++ IE PG
Sbjct: 101 VRNGEQDSILFIREAQRADSGR-YQLRVQLGGLEATA----TIDILV---IERPGPPQSI 152
Query: 809 QVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
++ DV + T+ W P G +LGY V++ S LW V + T C V L+
Sbjct: 153 KLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLII 211
Query: 869 DTEYEFRVIAVNKAG 883
Y FRV A N+ G
Sbjct: 212 GNSYAFRVFAENQCG 226
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 123 bits (308), Expect = 1e-27
Identities = 152/673 (22%), Positives = 259/673 (38%), Gaps = 60/673 (8%)
Query: 63 GDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKE 122
G+ P+F K V EG F ++ G +P ++W + +P++ SA++ N
Sbjct: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGM 215
Query: 123 HVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQ 182
VL++ + DD Y C+ N A + L + +G + + + + +A + +K+
Sbjct: 216 QVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI-QGLDSANRSFVRETKATNSDVRKE 274
Query: 183 -KKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEV--EAIRILK- 238
V +++ L+ L K G + + + K+E ++ R
Sbjct: 275 VTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQ 334
Query: 239 -PLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLR-IQYSLGKYDVKQMGTKYMLV 296
P+ K + T E + P + ++ G E R + +Q G V
Sbjct: 335 TPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDV 394
Query: 297 ISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSK-KE 355
+S ++R+ E KF + + +V E QT F +S +
Sbjct: 395 VSKA------------ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPK 442
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL--------- 406
P W G ++R + I V ED +H L + AR DSG +S A N
Sbjct: 443 PEVAWFLEGTPVRRQEG-SIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVT-LRWKKDGQLLMHGTKYS 465
+Q +L + + F S LK+ V E L+C + V + W +GQ + +
Sbjct: 502 LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKS------- 518
E AEL I+DA D G YT +A + + +A VTV E+ ++ KS
Sbjct: 562 ---EAGVAELHIQDALPEDHGTYTCLA--ENALGQVSCSAWVTVHEKKSSRKSEYLLPVA 616
Query: 519 -----------GMSDVHAATGSPAELCV-VLNDEKVEGVWLKDGKEITDLPGMQIVKQGA 566
G+SD+ GS + V V + E +WL +G EI + ++G
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676
Query: 567 VHKLIFPSMGPEHEGKYTFRAKGTESEA---SVFIADPPTIDPSVLEALAAHAITVKVGH 623
H L + PE G YT A + E +V P ++T +G
Sbjct: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQ 736
Query: 624 TAHIKVPFRGKPLPKVTWYKDGMEVTEEE-RVSMERGEDQALLTISNCVREDSGLILLKL 682
+ I G P P V W +DG + ++ + + ED L + +G + L
Sbjct: 737 SVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796
Query: 683 KNDHGSATATLHL 695
KN G + + L
Sbjct: 797 KNRVGECSCQVSL 809
Score = 87.8 bits (216), Expect = 6e-17
Identities = 76/325 (23%), Positives = 128/325 (39%), Gaps = 52/325 (16%)
Query: 517 KSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSM 575
K + DVH A G L C V +D +W +GK + + + ++G++ +
Sbjct: 1101 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKA 1160
Query: 576 GPEHEGKYTFRAK-----------------------------------------GTESEA 594
PE G Y AK GTES+A
Sbjct: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDA 1220
Query: 595 SVFIADPPTIDPSVLEALAAHAIT------VKVGHTAHIKVPFRGKPLPKVTWYKDGMEV 648
+V P P A+ I V+ G + + G TW K ++
Sbjct: 1221 TVKKKPAPKTPPKA--AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
Query: 649 TEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRV 708
E E + +E E+ + LTI +E G L ++N GS A ++L+V+D+P PP G
Sbjct: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
Query: 709 EFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEE 768
++ S + + W +GG V + +E K+W ++ + T+F+ +
Sbjct: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC--RSTSFNVQDLLP 1396
Query: 769 GKAYQFRILAVNSEGVSDPLETEEV 793
Y+FR+ A+N G S+P + E+
Sbjct: 1397 DHEYKFRVRAINVYGTSEPSQESEL 1421
Score = 71.2 bits (173), Expect = 6e-12
Identities = 60/228 (26%), Positives = 95/228 (41%), Gaps = 18/228 (7%)
Query: 988 ELDKGVRAMP----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGV 1043
E D V+ P PP A + VRAG ++ + +G+ P W K
Sbjct: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
Query: 1044 PTKGRE--TITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN 1101
+ E + S+N S+ I + ++ G Y +L++N+ G + +++ V D P PP
Sbjct: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAG 1336
Query: 1102 LRLFEEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLL 1160
++ +++TL+W S Y I D++ TW A S + V LL
Sbjct: 1337 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLL 1395
Query: 1161 PGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKD 1208
P +Y FRV A N G SEP + + + KP E KD
Sbjct: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGE----------KPEEPKD 1433
Score = 63.9 bits (154), Expect = 1e-09
Identities = 75/333 (22%), Positives = 126/333 (37%), Gaps = 50/333 (15%)
Query: 635 PLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLH 694
P + W +G + + + + + ++I + ED GL KND G A +
Sbjct: 1125 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQ 1184
Query: 695 LSVLDRP-------------KPPQGRVEFLELSGSCVHMKWKAPKD--NGGRP--VTQFI 737
++V D P +P L K APK P + QF
Sbjct: 1185 VTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFP 1244
Query: 738 VERRAVGKKSWIKIGEVDG-------------KVTNFSTNKVEEGK-AYQFRILAVNSEG 783
+++ +S G+V G ++ KVE + + ILA E
Sbjct: 1245 EDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEH 1304
Query: 784 -------VSDPLETEEVFAGNPI----EPPGFASQPQVTDVTKEAVTITWNAPTQDGGAP 832
V + L + + + +PP A P +D+ ++T++W + DGG+
Sbjct: 1305 CGCYTLLVENKLGSRQAQVNLTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSA 1362
Query: 833 VLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSS 892
V Y +E + W + + T V LL D EY+FRV A+N G +PS S
Sbjct: 1363 VQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
Query: 893 -SVVAKDPVKPPGLVQDLHVSDSSNSSISLAWR 924
+ V + P +P ++ VSD + +R
Sbjct: 1421 LTTVGEKPEEPK---DEVEVSDDDEKEPEVDYR 1450
Score = 52.8 bits (125), Expect = 2e-06
Identities = 74/343 (21%), Positives = 125/343 (36%), Gaps = 40/343 (11%)
Query: 1000 AAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE----TITKSK 1055
A PKF+ + + V+ + SG P P+V W +G P + +E +
Sbjct: 412 AFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAG 468
Query: 1056 NHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLT 1115
+H L+ + R DSG Y N G+ ++V L + E P+ ++
Sbjct: 469 SHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVE-------RLAVMEVAPSFSSVL 520
Query: 1116 WNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYT---------VTGLLPGRKYY 1166
+ + +D + TW + + + T + LP
Sbjct: 521 KDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGT 580
Query: 1167 FRVVARNEIGDSEPLDSRDTWL-INKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVL 1225
+ +A N +G S W+ +++ + S L P AP F+ L V+
Sbjct: 581 YTCLAENALGQV----SCSAWVTVHEKKSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVM 635
Query: 1226 RGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSV 1285
G TMT GNP P V I + F + +L I +D+G Y+
Sbjct: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 695
Query: 1286 LVENELGKDRSSCTLTVYDKDD----------KSVVASITESL 1318
N G+ R+ LTV + D +SV AS+ +S+
Sbjct: 696 EAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 738
Score = 51.2 bits (121), Expect = 6e-06
Identities = 67/274 (24%), Positives = 108/274 (39%), Gaps = 50/274 (18%)
Query: 55 TRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKI 114
+R ++P ++ P F+ P+ + EG A F RV+G +P ++W R +G PI +
Sbjct: 22 SRVDSMPLTEA-PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR-NGQPITSGGRF 79
Query: 115 FYD-SINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKR 173
D I L + + +D Y C A+N TV L V EG F K L +
Sbjct: 80 LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV-EG----SFAKQLGQ- 133
Query: 174 APPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEA 233
++SK F +E + + K +V V
Sbjct: 134 -------------------PVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVV-- 172
Query: 234 IRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKY 293
KE ++ F C + + P ++ W+KG PL+ + V +
Sbjct: 173 ---------KEGQMGR---FSCKITGR-PQPQVTWLKGNVPLQ---PSARVSVSEKNGMQ 216
Query: 294 MLVISNVNMNDAGIYSLSV----GDKRMSAELTV 323
+L I VN +D G+Y+ V G MSAEL++
Sbjct: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 48.5 bits (114), Expect = 4e-05
Identities = 30/94 (31%), Positives = 44/94 (46%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P+F T L V GQ +C G P+P VT KG+V + +++ + +G+ L I
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKD 1306
D G Y+ LV N GK S L++ D
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 45.8 bits (107), Expect = 3e-04
Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 6/113 (5%)
Query: 585 FRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKD 644
F A E+ S++ PP A + VK G G+P P+VTW K
Sbjct: 144 FSAPAVETRPSIWGECPPKF------ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKG 197
Query: 645 GMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
+ + RVS+ +L I ++D G+ + N G A+ + LS+
Sbjct: 198 NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 43.5 bits (101), Expect = 0.001
Identities = 74/336 (22%), Positives = 118/336 (35%), Gaps = 73/336 (21%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
AP F S+ LK V+ G + + G+P P + W +G P + + T ++
Sbjct: 513 APSF--SSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAEL 568
Query: 1061 LINSTKRSDSGVYRILLQNEFGEARYDIHVRVAD-------------FPRPPT------- 1100
I D G Y L +N G+ V V + P PT
Sbjct: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 628
Query: 1101 --NLRLFE--EVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTV 1156
+L++ + +V TV ++ N P+V + I D + +R + +
Sbjct: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED------FHFEQRGTQHSLCI 682
Query: 1157 TGLLPGRKYYFRVVARNEIGD---------SEPLDSRDTWLINKDQIQDLSAKLKPYEKK 1207
+ P + A N G+ EP D W I+K
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---------------- 726
Query: 1208 DWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVT-LYKGDVNITANSKFWYNSTSG 1266
PR VT GQ ++CA G+P PTV L G F
Sbjct: 727 -----PRSVT------ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
V TLV+ +G Y +L++N +G+ SC +++
Sbjct: 776 VFTLVLKKVQPWHAGQYEILLKNRVGE--CSCQVSL 809
Score = 42.4 bits (98), Expect = 0.003
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 6/104 (5%)
Query: 600 DPPTIDPSVLEALAAHAIT-----VKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERV 654
DP +D L A + +K G TA + RG P P+VTW+++G +T R
Sbjct: 20 DPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRF 79
Query: 655 SMERGEDQALLTISNCV-REDSGLILLKLKNDHGSATATLHLSV 697
++ G + + V ED G + N G+ T+ L+V
Sbjct: 80 LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 41.2 bits (95), Expect = 0.007
Identities = 29/121 (23%), Positives = 51/121 (42%), Gaps = 6/121 (4%)
Query: 39 VVRRKSSSIVEFFSLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHI 98
V +KSS E+ V P+ + P F++ + +G + +V GN P +
Sbjct: 600 VHEKKSSRKSEYLLPVA-----PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
Query: 99 SWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVT 158
W +G I+ES ++ +H L ++ + +D+ Y C A N + L V
Sbjct: 655 IW-LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Query: 159 E 159
E
Sbjct: 714 E 714
Score = 40.8 bits (94), Expect = 0.009
Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 1/82 (1%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGED-QALLTISNCVREDS 675
+ V G A G P P+V W+KD + E ++ ED L IS+ +D
Sbjct: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
Query: 676 GLILLKLKNDHGSATATLHLSV 697
K N G AT T L V
Sbjct: 1827 AKYTCKAVNSLGEATCTAELIV 1848
Score = 40.4 bits (93), Expect = 0.011
Identities = 69/306 (22%), Positives = 106/306 (34%), Gaps = 36/306 (11%)
Query: 420 KFVSNLKNVRVKERSRACLECELTS-KDVTLRWKKDGQLLMHGTKYSMNHEGKRAE-LII 477
KF S ++ VKE CE++ + W +G + +E + L +
Sbjct: 415 KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
Query: 478 EDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVK------SGMSDVHAATGSPA 531
A+ D G Y+ A + S + ERLA ++ S + D G
Sbjct: 475 LKARTRDSGTYSCTA---SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
Query: 532 EL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
L C V WL +G+ I + + V +L PE G YT A+
Sbjct: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
Query: 591 -------------------ESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPF 631
+SE + +A P L+ L+ + V G + V
Sbjct: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSD--LKVMDGSQVTMTVQV 646
Query: 632 RGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATA 691
G P P+V W +G E+ E E E+ Q L I ED+G + N G
Sbjct: 647 SGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 706
Query: 692 TLHLSV 697
L+V
Sbjct: 707 QAVLTV 712
Score = 39.3 bits (90), Expect = 0.025
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKR--SDSGVY 1073
V G L + S PP +IW +G K + I S+ S ++ K D G+Y
Sbjct: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
Query: 1074 RILLQNEFGEARYDIHVRVADFP 1096
+ + +N+ G+A V V D P
Sbjct: 1169 KCVAKNDAGQAECSCQVTVDDAP 1191
Score = 38.9 bits (89), Expect = 0.033
Identities = 59/269 (21%), Positives = 96/269 (35%), Gaps = 39/269 (14%)
Query: 65 SVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV 124
+ P F +K Q V EG K + + +V + I W +G +K + I
Sbjct: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL-NGKTLKTTKFIILSQEGSLCS 1154
Query: 125 LKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTE--GQEKMDFKKMLKKRAPPAPKKKQ 182
+ +E +D YKC+A ND A + + V + E +M +R PK
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRR----PKSSL 1210
Query: 183 KKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLED 242
V + + K K K M F E +K E++ +
Sbjct: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQF-------PEDQKVRAGESVELF----- 1258
Query: 243 KETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNM 302
KV T C W+K + ++ + K + + G+K L I
Sbjct: 1259 --GKVTGTQPITC-----------TWMKFRKQIQESEHM-KVENSENGSK--LTILAARQ 1302
Query: 303 NDAGIYSLSV----GDKRMSAELTVLDEP 327
G Y+L V G ++ LTV+D+P
Sbjct: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
Score = 38.5 bits (88), Expect = 0.043
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 5/85 (5%)
Query: 1002 PKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKS-KNHSQF 1060
PKF A +VV+ G +G P P V W K VP + ++ S KN Q
Sbjct: 161 PKF---ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
Query: 1061 L-INSTKRSDSGVYRILLQNEFGEA 1084
L I+ + D GVY L+ N G+A
Sbjct: 218 LEIHGVNQDDVGVYTCLVVNGSGKA 242
Score = 37.0 bits (84), Expect = 0.13
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 9/102 (8%)
Query: 1199 AKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSK 1258
A+ KP+ K P F ++ V+ G C G P P V +K D +I +
Sbjct: 1750 AEEKPHVK------PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH 1803
Query: 1259 FWYN-STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCT 1299
F + G C+L+I D Y+ N LG+ ++CT
Sbjct: 1804 FQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE--ATCT 1843
Score = 36.2 bits (82), Expect = 0.21
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 999 PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHS 1058
P+ P + + S + V G+ + + SG+PPP+VIW +G + E + +
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676
Query: 1059 Q--FLINSTKRSDSGVYRILLQNEFGEAR 1085
Q I D+G Y N GE R
Sbjct: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVR 705
Score = 36.2 bits (82), Expect = 0.21
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG-VCTL 1270
AP F L+ V G+ + C +P P ++ + +KF S G +C++
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDP-PATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
I +D G Y + +N+ G+ SC +TV D
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189
Score = 36.2 bits (82), Expect = 0.21
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 2/97 (2%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISW-KRESGIPIKESAKIFYDSINKEHVL 125
P F + + + EG A F +++G P + W K + I +I YD ++
Sbjct: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQE 162
+ + DD Y C A N +A T L+V +E
Sbjct: 1818 -ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
Score = 35.8 bits (81), Expect = 0.28
Identities = 30/121 (24%), Positives = 46/121 (38%), Gaps = 3/121 (2%)
Query: 1185 DTWLINKDQIQDLSAKLKP--YEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP 1242
D L+ I S + P + AP F+ P + + G G P P
Sbjct: 3 DVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP 62
Query: 1243 TVTLYKGDVNITANSKFWYN-STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLT 1301
VT ++ IT+ +F + G +LVI +D G Y+ N G + + LT
Sbjct: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
Query: 1302 V 1302
V
Sbjct: 123 V 123
Score = 35.4 bits (80), Expect = 0.37
Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 2/114 (1%)
Query: 1196 DLSAKLKPYEKKDWRHA--PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNI 1253
D + K KP K + A P+ + + V G+ + G T T K I
Sbjct: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
Query: 1254 TANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
+ ++ L I + G Y++LVEN+LG ++ LTV DK D
Sbjct: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
Score = 34.3 bits (77), Expect = 0.82
Identities = 23/99 (23%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Query: 61 PAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSIN 120
P + P F+ KP+ VTA G + + G+ P + W R+ K++ ++ +
Sbjct: 715 PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG--HFEVLQ 772
Query: 121 KEHV--LKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV 157
E V L L+ + + Y+ + N + VSL++
Sbjct: 773 NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
Score = 33.1 bits (74), Expect = 1.8
Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 6/103 (5%)
Query: 993 VRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-TKGRETI 1051
V +MP AP F L R ++ ++ G G P P V W ++G P T G +
Sbjct: 24 VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
Query: 1052 TKSKNHSQF--LINSTKRSDSGVYRILLQNEFGEARYDIHVRV 1092
F +I++ D G Y N G + + + V
Sbjct: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 31.2 bits (69), Expect = 6.9
Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Query: 330 FLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKI 388
F ++ ++V E A F+ ++ +P VW + + ++ ++I EDG +L I
Sbjct: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSLII 1818
Query: 389 KDARLSDSGEFSAEAGNLVQKAQLTIDRI 417
D D +++ +A N + +A T + I
Sbjct: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 123 bits (308), Expect = 1e-27
Identities = 152/673 (22%), Positives = 259/673 (38%), Gaps = 60/673 (8%)
Query: 63 GDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKE 122
G+ P+F K V EG F ++ G +P ++W + +P++ SA++ N
Sbjct: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGM 215
Query: 123 HVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQ 182
VL++ + DD Y C+ N A + L + +G + + + + +A + +K+
Sbjct: 216 QVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI-QGLDSANRSFVRETKATNSDVRKE 274
Query: 183 -KKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEV--EAIRILK- 238
V +++ L+ L K G + + + K+E ++ R
Sbjct: 275 VTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQ 334
Query: 239 -PLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLR-IQYSLGKYDVKQMGTKYMLV 296
P+ K + T E + P + ++ G E R + +Q G V
Sbjct: 335 TPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDV 394
Query: 297 ISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSK-KE 355
+S ++R+ E KF + + +V E QT F +S +
Sbjct: 395 VSKA------------ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPK 442
Query: 356 PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL--------- 406
P W G ++R + I V ED +H L + AR DSG +S A N
Sbjct: 443 PEVAWFLEGTPVRRQEG-SIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501
Query: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVT-LRWKKDGQLLMHGTKYS 465
+Q +L + + F S LK+ V E L+C + V + W +GQ + +
Sbjct: 502 LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561
Query: 466 MNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKS------- 518
E AEL I+DA D G YT +A + + +A VTV E+ ++ KS
Sbjct: 562 ---EAGVAELHIQDALPEDHGTYTCLA--ENALGQVSCSAWVTVHEKKSSRKSEYLLPVA 616
Query: 519 -----------GMSDVHAATGSPAELCV-VLNDEKVEGVWLKDGKEITDLPGMQIVKQGA 566
G+SD+ GS + V V + E +WL +G EI + ++G
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676
Query: 567 VHKLIFPSMGPEHEGKYTFRAKGTESEA---SVFIADPPTIDPSVLEALAAHAITVKVGH 623
H L + PE G YT A + E +V P ++T +G
Sbjct: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQ 736
Query: 624 TAHIKVPFRGKPLPKVTWYKDGMEVTEEE-RVSMERGEDQALLTISNCVREDSGLILLKL 682
+ I G P P V W +DG + ++ + + ED L + +G + L
Sbjct: 737 SVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796
Query: 683 KNDHGSATATLHL 695
KN G + + L
Sbjct: 797 KNRVGECSCQVSL 809
Score = 87.8 bits (216), Expect = 6e-17
Identities = 76/325 (23%), Positives = 128/325 (39%), Gaps = 52/325 (16%)
Query: 517 KSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSM 575
K + DVH A G L C V +D +W +GK + + + ++G++ +
Sbjct: 1101 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKA 1160
Query: 576 GPEHEGKYTFRAK-----------------------------------------GTESEA 594
PE G Y AK GTES+A
Sbjct: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDA 1220
Query: 595 SVFIADPPTIDPSVLEALAAHAIT------VKVGHTAHIKVPFRGKPLPKVTWYKDGMEV 648
+V P P A+ I V+ G + + G TW K ++
Sbjct: 1221 TVKKKPAPKTPPKA--AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
Query: 649 TEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRV 708
E E + +E E+ + LTI +E G L ++N GS A ++L+V+D+P PP G
Sbjct: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
Query: 709 EFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEE 768
++ S + + W +GG V + +E K+W ++ + T+F+ +
Sbjct: 1339 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC--RSTSFNVQDLLP 1396
Query: 769 GKAYQFRILAVNSEGVSDPLETEEV 793
Y+FR+ A+N G S+P + E+
Sbjct: 1397 DHEYKFRVRAINVYGTSEPSQESEL 1421
Score = 71.2 bits (173), Expect = 6e-12
Identities = 60/228 (26%), Positives = 95/228 (41%), Gaps = 18/228 (7%)
Query: 988 ELDKGVRAMP----PPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGV 1043
E D V+ P PP A + VRAG ++ + +G+ P W K
Sbjct: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
Query: 1044 PTKGRE--TITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTN 1101
+ E + S+N S+ I + ++ G Y +L++N+ G + +++ V D P PP
Sbjct: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAG 1336
Query: 1102 LRLFEEV-PNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLL 1160
++ +++TL+W S Y I D++ TW A S + V LL
Sbjct: 1337 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLL 1395
Query: 1161 PGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKD 1208
P +Y FRV A N G SEP + + + KP E KD
Sbjct: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGE----------KPEEPKD 1433
Score = 63.9 bits (154), Expect = 1e-09
Identities = 75/333 (22%), Positives = 126/333 (37%), Gaps = 50/333 (15%)
Query: 635 PLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLH 694
P + W +G + + + + + ++I + ED GL KND G A +
Sbjct: 1125 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQ 1184
Query: 695 LSVLDRP-------------KPPQGRVEFLELSGSCVHMKWKAPKD--NGGRP--VTQFI 737
++V D P +P L K APK P + QF
Sbjct: 1185 VTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFP 1244
Query: 738 VERRAVGKKSWIKIGEVDG-------------KVTNFSTNKVEEGK-AYQFRILAVNSEG 783
+++ +S G+V G ++ KVE + + ILA E
Sbjct: 1245 EDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEH 1304
Query: 784 -------VSDPLETEEVFAGNPI----EPPGFASQPQVTDVTKEAVTITWNAPTQDGGAP 832
V + L + + + +PP A P +D+ ++T++W + DGG+
Sbjct: 1305 CGCYTLLVENKLGSRQAQVNLTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSA 1362
Query: 833 VLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSS 892
V Y +E + W + + T V LL D EY+FRV A+N G +PS S
Sbjct: 1363 VQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
Query: 893 -SVVAKDPVKPPGLVQDLHVSDSSNSSISLAWR 924
+ V + P +P ++ VSD + +R
Sbjct: 1421 LTTVGEKPEEPK---DEVEVSDDDEKEPEVDYR 1450
Score = 52.8 bits (125), Expect = 2e-06
Identities = 74/343 (21%), Positives = 125/343 (36%), Gaps = 40/343 (11%)
Query: 1000 AAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRE----TITKSK 1055
A PKF+ + + V+ + SG P P+V W +G P + +E +
Sbjct: 412 AFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAG 468
Query: 1056 NHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLT 1115
+H L+ + R DSG Y N G+ ++V L + E P+ ++
Sbjct: 469 SHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVE-------RLAVMEVAPSFSSVL 520
Query: 1116 WNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYT---------VTGLLPGRKYY 1166
+ + +D + TW + + + T + LP
Sbjct: 521 KDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGT 580
Query: 1167 FRVVARNEIGDSEPLDSRDTWL-INKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVL 1225
+ +A N +G S W+ +++ + S L P AP F+ L V+
Sbjct: 581 YTCLAENALGQV----SCSAWVTVHEKKSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVM 635
Query: 1226 RGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSV 1285
G TMT GNP P V I + F + +L I +D+G Y+
Sbjct: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 695
Query: 1286 LVENELGKDRSSCTLTVYDKDD----------KSVVASITESL 1318
N G+ R+ LTV + D +SV AS+ +S+
Sbjct: 696 EAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 738
Score = 51.2 bits (121), Expect = 6e-06
Identities = 67/274 (24%), Positives = 108/274 (39%), Gaps = 50/274 (18%)
Query: 55 TRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKI 114
+R ++P ++ P F+ P+ + EG A F RV+G +P ++W R +G PI +
Sbjct: 22 SRVDSMPLTEA-PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR-NGQPITSGGRF 79
Query: 115 FYD-SINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKR 173
D I L + + +D Y C A+N TV L V EG F K L +
Sbjct: 80 LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV-EG----SFAKQLGQ- 133
Query: 174 APPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEA 233
++SK F +E + + K +V V
Sbjct: 134 -------------------PVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVV-- 172
Query: 234 IRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKY 293
KE ++ F C + + P ++ W+KG PL+ + V +
Sbjct: 173 ---------KEGQMGR---FSCKITGR-PQPQVTWLKGNVPLQ---PSARVSVSEKNGMQ 216
Query: 294 MLVISNVNMNDAGIYSLSV----GDKRMSAELTV 323
+L I VN +D G+Y+ V G MSAEL++
Sbjct: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 48.5 bits (114), Expect = 4e-05
Identities = 30/94 (31%), Positives = 44/94 (46%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P+F T L V GQ +C G P+P VT KG+V + +++ + +G+ L I
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKD 1306
D G Y+ LV N GK S L++ D
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 45.8 bits (107), Expect = 3e-04
Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 6/113 (5%)
Query: 585 FRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKD 644
F A E+ S++ PP A + VK G G+P P+VTW K
Sbjct: 144 FSAPAVETRPSIWGECPPKF------ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKG 197
Query: 645 GMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
+ + RVS+ +L I ++D G+ + N G A+ + LS+
Sbjct: 198 NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 43.5 bits (101), Expect = 0.001
Identities = 74/336 (22%), Positives = 118/336 (35%), Gaps = 73/336 (21%)
Query: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
AP F S+ LK V+ G + + G+P P + W +G P + + T ++
Sbjct: 513 APSF--SSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAEL 568
Query: 1061 LINSTKRSDSGVYRILLQNEFGEARYDIHVRVAD-------------FPRPPT------- 1100
I D G Y L +N G+ V V + P PT
Sbjct: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 628
Query: 1101 --NLRLFE--EVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTV 1156
+L++ + +V TV ++ N P+V + I D + +R + +
Sbjct: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED------FHFEQRGTQHSLCI 682
Query: 1157 TGLLPGRKYYFRVVARNEIGD---------SEPLDSRDTWLINKDQIQDLSAKLKPYEKK 1207
+ P + A N G+ EP D W I+K
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---------------- 726
Query: 1208 DWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVT-LYKGDVNITANSKFWYNSTSG 1266
PR VT GQ ++CA G+P PTV L G F
Sbjct: 727 -----PRSVT------ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
Query: 1267 VCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
V TLV+ +G Y +L++N +G+ SC +++
Sbjct: 776 VFTLVLKKVQPWHAGQYEILLKNRVGE--CSCQVSL 809
Score = 42.4 bits (98), Expect = 0.003
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 6/104 (5%)
Query: 600 DPPTIDPSVLEALAAHAIT-----VKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERV 654
DP +D L A + +K G TA + RG P P+VTW+++G +T R
Sbjct: 20 DPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRF 79
Query: 655 SMERGEDQALLTISNCV-REDSGLILLKLKNDHGSATATLHLSV 697
++ G + + V ED G + N G+ T+ L+V
Sbjct: 80 LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 41.2 bits (95), Expect = 0.007
Identities = 29/121 (23%), Positives = 51/121 (42%), Gaps = 6/121 (4%)
Query: 39 VVRRKSSSIVEFFSLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHI 98
V +KSS E+ V P+ + P F++ + +G + +V GN P +
Sbjct: 600 VHEKKSSRKSEYLLPVA-----PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
Query: 99 SWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVT 158
W +G I+ES ++ +H L ++ + +D+ Y C A N + L V
Sbjct: 655 IW-LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Query: 159 E 159
E
Sbjct: 714 E 714
Score = 40.8 bits (94), Expect = 0.009
Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 1/82 (1%)
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGED-QALLTISNCVREDS 675
+ V G A G P P+V W+KD + E ++ ED L IS+ +D
Sbjct: 1818 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1877
Query: 676 GLILLKLKNDHGSATATLHLSV 697
K N G AT T L V
Sbjct: 1878 AKYTCKAVNSLGEATCTAELIV 1899
Score = 40.4 bits (93), Expect = 0.011
Identities = 69/306 (22%), Positives = 106/306 (34%), Gaps = 36/306 (11%)
Query: 420 KFVSNLKNVRVKERSRACLECELTS-KDVTLRWKKDGQLLMHGTKYSMNHEGKRAE-LII 477
KF S ++ VKE CE++ + W +G + +E + L +
Sbjct: 415 KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
Query: 478 EDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVK------SGMSDVHAATGSPA 531
A+ D G Y+ A + S + ERLA ++ S + D G
Sbjct: 475 LKARTRDSGTYSCTA---SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
Query: 532 EL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGT 590
L C V WL +G+ I + + V +L PE G YT A+
Sbjct: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
Query: 591 -------------------ESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPF 631
+SE + +A P L+ L+ + V G + V
Sbjct: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSD--LKVMDGSQVTMTVQV 646
Query: 632 RGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATA 691
G P P+V W +G E+ E E E+ Q L I ED+G + N G
Sbjct: 647 SGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 706
Query: 692 TLHLSV 697
L+V
Sbjct: 707 QAVLTV 712
Score = 39.3 bits (90), Expect = 0.025
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKR--SDSGVY 1073
V G L + S PP +IW +G K + I S+ S ++ K D G+Y
Sbjct: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
Query: 1074 RILLQNEFGEARYDIHVRVADFP 1096
+ + +N+ G+A V V D P
Sbjct: 1169 KCVAKNDAGQAECSCQVTVDDAP 1191
Score = 38.9 bits (89), Expect = 0.033
Identities = 59/269 (21%), Positives = 96/269 (35%), Gaps = 39/269 (14%)
Query: 65 SVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHV 124
+ P F +K Q V EG K + + +V + I W +G +K + I
Sbjct: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL-NGKTLKTTKFIILSQEGSLCS 1154
Query: 125 LKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTE--GQEKMDFKKMLKKRAPPAPKKKQ 182
+ +E +D YKC+A ND A + + V + E +M +R PK
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRR----PKSSL 1210
Query: 183 KKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLED 242
V + + K K K M F E +K E++ +
Sbjct: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQF-------PEDQKVRAGESVELF----- 1258
Query: 243 KETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNM 302
KV T C W+K + ++ + K + + G+K L I
Sbjct: 1259 --GKVTGTQPITC-----------TWMKFRKQIQESEHM-KVENSENGSK--LTILAARQ 1302
Query: 303 NDAGIYSLSV----GDKRMSAELTVLDEP 327
G Y+L V G ++ LTV+D+P
Sbjct: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
Score = 38.5 bits (88), Expect = 0.043
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 5/85 (5%)
Query: 1002 PKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKS-KNHSQF 1060
PKF A +VV+ G +G P P V W K VP + ++ S KN Q
Sbjct: 161 PKF---ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
Query: 1061 L-INSTKRSDSGVYRILLQNEFGEA 1084
L I+ + D GVY L+ N G+A
Sbjct: 218 LEIHGVNQDDVGVYTCLVVNGSGKA 242
Score = 37.0 bits (84), Expect = 0.13
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 9/102 (8%)
Query: 1199 AKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSK 1258
A+ KP+ K P F ++ V+ G C G P P V +K D +I +
Sbjct: 1801 AEEKPHVK------PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH 1854
Query: 1259 FWYN-STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCT 1299
F + G C+L+I D Y+ N LG+ ++CT
Sbjct: 1855 FQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE--ATCT 1894
Score = 36.2 bits (82), Expect = 0.21
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 999 PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHS 1058
P+ P + + S + V G+ + + SG+PPP+VIW +G + E + +
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676
Query: 1059 Q--FLINSTKRSDSGVYRILLQNEFGEAR 1085
Q I D+G Y N GE R
Sbjct: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGEVR 705
Score = 36.2 bits (82), Expect = 0.21
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSG-VCTL 1270
AP F L+ V G+ + C +P P ++ + +KF S G +C++
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDP-PATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
Query: 1271 VIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
I +D G Y + +N+ G+ SC +TV D
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189
Score = 36.2 bits (82), Expect = 0.21
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 2/97 (2%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISW-KRESGIPIKESAKIFYDSINKEHVL 125
P F + + + EG A F +++G P + W K + I +I YD ++
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQE 162
+ + DD Y C A N +A T L+V +E
Sbjct: 1869 -ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904
Score = 35.8 bits (81), Expect = 0.28
Identities = 30/121 (24%), Positives = 46/121 (38%), Gaps = 3/121 (2%)
Query: 1185 DTWLINKDQIQDLSAKLKP--YEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRP 1242
D L+ I S + P + AP F+ P + + G G P P
Sbjct: 3 DVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEP 62
Query: 1243 TVTLYKGDVNITANSKFWYN-STSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLT 1301
VT ++ IT+ +F + G +LVI +D G Y+ N G + + LT
Sbjct: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
Query: 1302 V 1302
V
Sbjct: 123 V 123
Score = 35.4 bits (80), Expect = 0.37
Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 2/114 (1%)
Query: 1196 DLSAKLKPYEKKDWRHA--PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNI 1253
D + K KP K + A P+ + + V G+ + G T T K I
Sbjct: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
Query: 1254 TANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDD 1307
+ ++ L I + G Y++LVEN+LG ++ LTV DK D
Sbjct: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
Score = 34.3 bits (77), Expect = 0.82
Identities = 23/99 (23%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Query: 61 PAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSIN 120
P + P F+ KP+ VTA G + + G+ P + W R+ K++ ++ +
Sbjct: 715 PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG--HFEVLQ 772
Query: 121 KEHV--LKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV 157
E V L L+ + + Y+ + N + VSL++
Sbjct: 773 NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
Score = 33.1 bits (74), Expect = 1.8
Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 6/103 (5%)
Query: 993 VRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-TKGRETI 1051
V +MP AP F L R ++ ++ G G P P V W ++G P T G +
Sbjct: 24 VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
Query: 1052 TKSKNHSQF--LINSTKRSDSGVYRILLQNEFGEARYDIHVRV 1092
F +I++ D G Y N G + + + V
Sbjct: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 31.2 bits (69), Expect = 6.9
Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Query: 330 FLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKI 388
F ++ ++V E A F+ ++ +P VW + + ++ ++I EDG +L I
Sbjct: 1811 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSLII 1869
Query: 389 KDARLSDSGEFSAEAGNLVQKAQLTIDRI 417
D D +++ +A N + +A T + I
Sbjct: 1870 SDVCGDDDAKYTCKAVNSLGEATCTAELI 1898
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 121 bits (304), Expect = 4e-27
Identities = 223/1081 (20%), Positives = 420/1081 (38%), Gaps = 125/1081 (11%)
Query: 64 DSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEH 123
+S P ++ A G + + G+ +P W +++ +P++ S + F ++
Sbjct: 222 NSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDN-MPLELSGR-FQKTVTG-- 277
Query: 124 VLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQK 183
L +E + DS +Y C SN + A L V + + + +K
Sbjct: 278 -LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCS 336
Query: 184 KVANEKEML------EILS-----KVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVE 232
E + L EIL+ ++ + E + M++ G + K +
Sbjct: 337 VTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQD 396
Query: 233 AIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSL--------GKY 284
++++ LED K+ + + ++ +P M +KGT I ++L G +
Sbjct: 397 YVQVV--LEDGTPKI-ISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSH 453
Query: 285 DVKQMGTKYMLVISNVNMN-----DAGIYSLSVGDKRMSAELTVLDEPLKFLG--EMKPV 337
+ QM T V+S +N++ D G+Y + + SA + + + G ++P+
Sbjct: 454 RISQMITSEGNVVSYLNISSSQVRDGGVYRCTANN---SAGVVLYQARINVRGPASIRPM 510
Query: 338 K----VTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARL 393
K + R T + + + W N L + + ++ +G TLK+ D +
Sbjct: 511 KNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHR-QVAFENNG---TLKLSDVQK 566
Query: 394 S-DSGEFSAEAGNLVQKAQLTIDR---IPIK---FVSNLKNVRVKERSRACLECELTSKD 446
D GE++ N++ + QL+ + + +K F+ + R R + C + S D
Sbjct: 567 EVDEGEYTC---NVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGD 623
Query: 447 --VTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYST 504
+T+ W+KDG+ + ++++ + L I + L G YT +A + E+ S
Sbjct: 624 LPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQ 683
Query: 505 AIVTVEERLATVKSGMSDVH--------AATGSPAELCVVLNDEKVEGVWLKDGKEITDL 556
IV V + ++ +A G P V + +G + + I
Sbjct: 684 LIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVW---KFSKGAGVPQFQPIALN 740
Query: 557 PGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAK---GTESEASVF--IADPPTIDPSVLEA 611
+Q++ G+ L+ + E G Y + G + S++ + P I
Sbjct: 741 GRIQVLSNGS---LLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTT 797
Query: 612 LAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEER----VSMERGEDQ-ALLT 666
LA ++ TAH + P V W K+ + E + E GE+ + L
Sbjct: 798 LATQGQKKEMSCTAHGEKPI------IVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQ 851
Query: 667 ISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPK 726
I VREDSG N +G + L+V + P PP+ +E ++ + ++W
Sbjct: 852 ILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPE--IEIKDVKARTITLRWTMGF 909
Query: 727 DNGGRPVTQFIVE--RRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGV 784
D G P+T + +E ++ S + +V ++ + + + Y R+ A N G
Sbjct: 910 D-GNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGK 968
Query: 785 SDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQD-GGAPVLGYIVERRK- 842
S+P E + P G + + ++ +++ +TW AP + + GY + R+
Sbjct: 969 SEP-SNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREY 1027
Query: 843 -KGSNLWVPVNKDPIQGTK--CTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD- 898
G N + G T+D L + T+Y V A N+AG G S + +D
Sbjct: 1028 STGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDV 1087
Query: 899 PVKPPGLVQDLHVSDSSNSSISLAW----REPAEGDPPSGYILEMRAEDTKEWSKCTKIP 954
P PP VQ + +S SIS++W +E G ++ E + I
Sbjct: 1088 PSYPPENVQAI---ATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNIT 1144
Query: 955 ISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE--LDKGVRAMP-PPAAPKFDLSAR-- 1009
+ + GL + Y ++ A AG G E + +P PPA K ++
Sbjct: 1145 TTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASM 1204
Query: 1010 --------LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFL 1061
LK + ++R T C H P P VI + + P I + Q+
Sbjct: 1205 VFVSWLPPLKLNGIIRKYTVFCSH------PYPTVISEFEASPDSFSYRIPNLSRNRQYS 1258
Query: 1062 I 1062
+
Sbjct: 1259 V 1259
Score = 109 bits (273), Expect = 2e-23
Identities = 227/1100 (20%), Positives = 410/1100 (37%), Gaps = 173/1100 (15%)
Query: 295 LVISNVNMNDAGIYSLSVGDKRMSAE----LTVLDEPLKFLGEM--KPVKVTERQTAVFE 348
L++ ++ +D G Y V ++SA+ + + D K + K V E + +
Sbjct: 370 LIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCN 429
Query: 349 IRLSKKEPNFVWKFNGKELKRDDKYEIT---VSEDGLTHTLKIKDARLSDSGEFSAEAGN 405
++ P W + + + + I+ SE + L I +++ D G + A N
Sbjct: 430 VK-GTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANN 488
Query: 406 ----LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDV-TLRWKKDGQLLMH 460
++ +A++ + R P + +KN+ + C + +++W K+ LL
Sbjct: 489 SAGVVLYQARINV-RGPAS-IRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLL-- 544
Query: 461 GTKYSMNHEGKRAE----LIIEDAQLS-DGGEYTV-VAMQDGDPTEYYSTAIVTVEERLA 514
NH E L + D Q D GEYT V +Q T V V +
Sbjct: 545 ----PFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQ 600
Query: 515 TVKSGMSDVHAATGSPAELCVVLN-DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFP 573
+ + P CVV++ D + W KDG+ I G+ I L
Sbjct: 601 PFEFPRFSIGQRVFIP---CVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRIS 657
Query: 574 SMGPEHEGKYTFRAKG----TESEASVFIADPP--TIDPSVLEALAAHAITVKVGHTAHI 627
++ H G YT A+ E ++ + + PP + P + + A+ +
Sbjct: 658 NLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSA---- 713
Query: 628 KVPFRGKPLPKVTW-YKDGMEVTEEERVSMERGEDQAL----LTISNCVREDSGLILLKL 682
G P+P + W + G V + + +++ G Q L L I + V EDSG L K+
Sbjct: 714 ----EGYPVPTIVWKFSKGAGVPQFQPIALN-GRIQVLSNGSLLIKHVVEEDSGYYLCKV 768
Query: 683 KNDHGS-ATATLHLSVL---------DRPKPPQGRVEFLELSG---SCVHMKWKAPKDNG 729
ND G+ + +++L+V + QG+ + + + + ++W+
Sbjct: 769 SNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRII 828
Query: 730 GRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLE 789
+ +++V + VG+ EV + T + + G F A+NS G +
Sbjct: 829 NPEMARYLVSTKEVGE-------EVISTLQILPTVREDSGF---FSCHAINSYGEDRGII 878
Query: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
++ P +PP + ++ DV +T+ W DG +P+ GY +E + K S+ W
Sbjct: 879 --QLTVQEPPDPP----EIEIKDVKARTITLRWTMGF-DGNSPITGYDIECKNK-SDSW- 929
Query: 850 PVNKDPIQGTK--------CTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVK 901
D Q TK T+ + + Y R+ A N+ G +PS + + D
Sbjct: 930 ----DSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPS--NELTITADEAA 983
Query: 902 PPGLVQDLHVSDSSNSSISLAWREPA---EGDPPSGYILEMRAEDTKEWSKCTKIPISGT 958
P G Q++H+ S+ SI + W+ P + GY + R T + I + +
Sbjct: 984 PDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTS 1043
Query: 959 ----CYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHM 1014
YT+ L + +Y ++A N AG G + P+ P ++ A S
Sbjct: 1044 GDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPE 1103
Query: 1015 VVRAGTALCIHAAFSGSPPPD--VIWQK--DGV-----------PTKGRETITKSKNHSQ 1059
+ + A +G + W DG P+ + + K N+S
Sbjct: 1104 SISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSI 1163
Query: 1060 FLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHS 1119
++ T+ D + + F + D+ P PP ++ + V ++W
Sbjct: 1164 QVLAFTRAGDG----VRSEQIFTRTKEDV-------PGPPAGVKAAAASASMVFVSW--L 1210
Query: 1120 PDVQEDGEAHYIIMKRDASTATWYTAAERVF-----SNKYTVTGLLPGRKYYFRVVARNE 1174
P ++ +G II K + Y F S Y + L R+Y VVA
Sbjct: 1211 PPLKLNG----IIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTS 1266
Query: 1175 IGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTC 1234
G + +I + + A++ + + TP +D + C
Sbjct: 1267 AGRGNSSE-----IITVEPLAKAPARILTF-------SGTVTTPWM-------KDIVLPC 1307
Query: 1235 AFLGNPRPTVTLYKGD------VNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVE 1288
+G+P P V K V I + N + +I T +DSG YS +
Sbjct: 1308 KAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGS-----FIIRTVKAEDSGYYSCIAN 1362
Query: 1289 NELGKDRSSCTLTVYDKDDK 1308
N G D L V D+
Sbjct: 1363 NNWGSDEIILNLQVQVPPDQ 1382
Score = 84.0 bits (206), Expect = 9e-16
Identities = 179/865 (20%), Positives = 326/865 (37%), Gaps = 84/865 (9%)
Query: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGN---LVQKAQLTIDR 416
W+ +G+ + +T+ T +L+I + L +G ++ A N V+ I R
Sbjct: 630 WQKDGRPIP--GSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVR 687
Query: 417 IPIKFVSNLKNVRVKERSRACLECELTSKDV-TLRWK-KDGQLLMHGTKYSMNHEGK--- 471
+P KFV ++ L C V T+ WK G + ++N +
Sbjct: 688 VPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLS 747
Query: 472 RAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPA 531
L+I+ D G Y + D S ++ + A + S + A G
Sbjct: 748 NGSLLIKHVVEEDSGYY--LCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKK 805
Query: 532 ELCVVLNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHKLIFPSMG-----PEHEGKYTF 585
E+ + EK V W K+ + I +V V + + ++ E G ++
Sbjct: 806 EMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSC 865
Query: 586 RAKGTESE----ASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW 641
A + E + + +PP DP +E A T+ + T + F G +T
Sbjct: 866 HAINSYGEDRGIIQLTVQEPP--DPPEIEIKDVKARTITLRWT----MGFDGNS--PITG 917
Query: 642 YKDGMEVTEEERVSMERGEDQA----LLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697
Y + + S +R +D + TI + + I + KN G + + L++
Sbjct: 918 YDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTI 977
Query: 698 LDRPKPPQG---RVEFLELSGSCVHMKWKAPK---DNGGRPVTQFIVERRAVGKKSWIKI 751
P G V +S + + WKAPK NG Q + G I
Sbjct: 978 TADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNI 1037
Query: 752 GEVD--GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQP- 808
VD G ++ + + + Y + A N G ++E+ + P + +
Sbjct: 1038 ISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGP--SSQEIITTTLEDVPSYPPENV 1095
Query: 809 QVTDVTKEAVTITWNAPTQDGGAPVL-GY--IVERRKKGSNLWVPVNKDPIQGTKCTVDG 865
Q + E+++I+W+ +++ +L G+ I L N Q + +DG
Sbjct: 1096 QAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPS-LELDG 1154
Query: 866 LLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWRE 925
L + T Y +V+A +AG G V S + + PG + + +S S + ++W
Sbjct: 1155 LEKYTNYSIQVLAFTRAGDG---VRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLP 1211
Query: 926 PAEGDPPSGYILEMRAEDTKEW----SKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEA 981
P + +G I + + + S+ P S + Y + L ++Y + AV A
Sbjct: 1212 PLK---LNGIIRKYTVFCSHPYPTVISEFEASPDSFS-YRIPNLSRNRQYSVWVVAVTSA 1267
Query: 982 GVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTA-------LCIHAAFSGSPPP 1034
G G E+ + P AP + ++ +GT + + G P P
Sbjct: 1268 GRGNSSEI---ITVEPLAKAP---------ARILTFSGTVTTPWMKDIVLPCKAVGDPSP 1315
Query: 1035 DVIWQKDGVPTKGRETITKSKN---HSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVR 1091
V W KD T TI ++ + F+I + K DSG Y + N +G ++++
Sbjct: 1316 AVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQ 1375
Query: 1092 VADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFS 1151
V P P L + + +++TL+W D YI+ + ++ W +
Sbjct: 1376 VQVPPDQP-RLTVSKTTSSSITLSWLPG-DNGGSSIRGYILQYSEDNSEQWGSFPISPSE 1433
Query: 1152 NKYTVTGLLPGRKYYFRVVARNEIG 1176
Y + L G Y F + A+N +G
Sbjct: 1434 RSYRLENLKCGTWYKFTLTAQNGVG 1458
Score = 67.0 bits (162), Expect = 1e-10
Identities = 65/260 (25%), Positives = 109/260 (41%), Gaps = 24/260 (9%)
Query: 633 GKPLPKVTWYKDGME----VTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGS 688
G P P V W KD VT + R S+ + T+ EDSG N+ GS
Sbjct: 1311 GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVK---AEDSGYYSCIANNNWGS 1367
Query: 689 ATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSW 748
L+L V + P Q R+ + + S + + W P DNGG + +I++ + W
Sbjct: 1368 DEIILNLQV--QVPPDQPRLTVSKTTSSSITLSW-LPGDNGGSSIRGYILQYSEDNSEQW 1424
Query: 749 IKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPI-EPPGFASQ 807
+ ++ ++ G Y+F + A N G P E+ + + P F+ +
Sbjct: 1425 GSF-PISPSERSYRLENLKCGTWYKFTLTAQNGVG---PGRISEIIEAKTLGKEPQFSKE 1480
Query: 808 PQV---TDVTKEAVT-ITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTV 863
++ + T+ + I WN DGG P+ + +E R G+ +W + + +
Sbjct: 1481 QELFASINTTRVRLNLIGWN----DGGCPITSFTLEYRPFGTTVWTTAQRTSLSKSYILY 1536
Query: 864 DGLLEDTEYEFRVIAVNKAG 883
D L E T YE ++ N AG
Sbjct: 1537 D-LQEATWYELQMRVCNSAG 1555
Score = 41.2 bits (95), Expect = 0.007
Identities = 78/307 (25%), Positives = 114/307 (37%), Gaps = 44/307 (14%)
Query: 699 DRPKPPQGRVEFLELSGSCVHMKWKAPKDNGG--RPVTQFIVERRAVGKKSWIKIGEVDG 756
D P PP G V+ S S V + W P G R T F I E +
Sbjct: 1187 DVPGPPAG-VKAAAASASMVFVSWLPPLKLNGIIRKYTVFCSHPYPT------VISEFEA 1239
Query: 757 KVTNFSTN--KVEEGKAYQFRILAVNSEGVSDPLE--TEEVFAGNP---IEPPGFASQPQ 809
+FS + + Y ++AV S G + E T E A P + G + P
Sbjct: 1240 SPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARILTFSGTVTTPW 1299
Query: 810 VTDVTKEAVTITWNAPT-----QDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVD 864
+ D+ + +P G P L I RR SN G+
Sbjct: 1300 MKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSN-----------GSFIIRT 1348
Query: 865 GLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWR 924
ED+ Y + IA N G S ++ V+ P L VS +++SSI+L+W
Sbjct: 1349 VKAEDSGY-YSCIANNNWG-------SDEIILNLQVQVPPDQPRLTVSKTTSSSITLSWL 1400
Query: 925 EPAE--GDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAG 982
P + G GYIL+ +++++W P S Y + L Y F + A N G
Sbjct: 1401 -PGDNGGSSIRGYILQYSEDNSEQWGSFPISP-SERSYRLENLKCGTWYKFTLTAQNGVG 1458
Query: 983 VGEPVEL 989
G E+
Sbjct: 1459 PGRISEI 1465
Score = 37.0 bits (84), Expect = 0.13
Identities = 54/297 (18%), Positives = 112/297 (37%), Gaps = 55/297 (18%)
Query: 1019 GTALCIHAAFSGSPPPDVIWQKDG-VPTKGRETITKSKNHSQFLINSTKRSDSGVYRILL 1077
G+ + + + +G+ ++ W ++G + G+ NH +++ +SD G Y+ +
Sbjct: 328 GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFV 387
Query: 1078 QNEFGEARYDIHVRVAD--------------FPRPPTNLRLFEEVPNTVTLTWNHSPDVQ 1123
+ + A+ + V + D P P +L + T+TW D
Sbjct: 388 RKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPI 447
Query: 1124 EDGEAHYI--IMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPL 1181
G +H I ++ + + ++ + S++ G+ +R A N
Sbjct: 448 LKGGSHRISQMITSEGNVVSYL----NISSSQVRDGGV-------YRCTANN-------- 488
Query: 1182 DSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPR 1241
SA + Y+ + P + P+K T + G+D + C +G P
Sbjct: 489 ----------------SAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPY 532
Query: 1242 PTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDY--SVLVENELGKDRS 1296
++ YK + N + +G L + D G+Y +VLV+ +L +S
Sbjct: 533 YSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEV-DEGEYTCNVLVQPQLSTSQS 588
Score = 36.2 bits (82), Expect = 0.21
Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 7/108 (6%)
Query: 582 KYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW 641
+YT + + S A +F++DP PS+L+ G + G P P W
Sbjct: 202 RYTGETRQSNS-ARLFVSDPANSAPSILDGFDHR--KAMAGQRVELPCKALGHPEPDYRW 258
Query: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA 689
KD M + R + L I N DSG + ++ N +G+A
Sbjct: 259 LKDNMPLELSGRFQ----KTVTGLLIENIRPSDSGSYVCEVSNRYGTA 302
Score = 35.4 bits (80), Expect = 0.37
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 1013 HMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGV 1072
H AG + + G P PD W KD +P + K+ + LI + + SDSG
Sbjct: 233 HRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTV--TGLLIENIRPSDSGS 290
Query: 1073 YRILLQNEFGEAR 1085
Y + N +G A+
Sbjct: 291 YVCEVSNRYGTAK 303
Score = 31.6 bits (70), Expect = 5.3
Identities = 21/81 (25%), Positives = 31/81 (38%), Gaps = 4/81 (4%)
Query: 1212 APRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLV 1271
AP + + GQ + C LG+P P K ++ + + +F T L+
Sbjct: 224 APSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG----LL 279
Query: 1272 IPTCTLKDSGDYSVLVENELG 1292
I DSG Y V N G
Sbjct: 280 IENIRPSDSGSYVCEVSNRYG 300
>gi|83281200 protogenin [Homo sapiens]
Length = 1150
Score = 120 bits (302), Expect = 7e-27
Identities = 188/912 (20%), Positives = 351/912 (38%), Gaps = 79/912 (8%)
Query: 328 LKFLGEMKPVKVTERQTAVFEIRLSKKEP-NFVWKFNGKELKRDDKYEITVSEDGLTHTL 386
L F+ E + V VT + V + + + P W NG ++ + + E+ + +
Sbjct: 39 LSFVKEPQDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNGSLYISEV 98
Query: 387 KIKDARLSDSGEFSAEAGN-----LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECE 441
+ + SD G + A N L QKA L + I V + + V E A C+
Sbjct: 99 EGRRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFEVQPI-STEVHEGGVARFACK 157
Query: 442 LTSKD-VTLRWKKDGQLL-MHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPT 499
++S + W+ + L M + + G L I D D G Y +A
Sbjct: 158 ISSHPPAVITWEFNRTTLPMTMDRITALPTGV---LQIYDVSQRDSGNYRCIAATVAHRR 214
Query: 500 EYYSTAIVTVEERLA------TVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKE 552
+ ++ + + + T+ +G ++ + L C+ + K W + +
Sbjct: 215 KSMEASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHK 274
Query: 553 ITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAK--GTESEASVFIADPPTIDPSVLE 610
D+ +++ G L+ + +H G Y RA GT + PS +E
Sbjct: 275 SIDVFNTRVLGNG---NLMISDVRLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPSFVE 331
Query: 611 ALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNC 670
++T TA G P PK++W K+G ++ R+ M + L I+
Sbjct: 332 W--PESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYNSK----LVINQI 385
Query: 671 VREDSGLILLKLKNDHGSATATLHLSVL---DRPKPPQGRVEFLELSGSCVHMKWKAPKD 727
+ ED + +N GS + L+V+ DRP P V +S S + + W+ P
Sbjct: 386 IPEDDAIYQCMAENSQGSILSRARLTVVMSEDRPSAPY-NVHAETMSSSAILLAWERPLY 444
Query: 728 NGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDP 787
N + + + +A G + + T++ + +E Y F I+A G S
Sbjct: 445 NSDKVIAYSVHYMKAEGLNNEEYQVVIGNDTTHYIIDDLEPASNYTFYIVAYMPMGASQM 504
Query: 788 LE--TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITW-NAPTQDGGAPVLGYIVERRKKG 844
+ T+ P+ PP + +T + + I+W P + V+ Y + R
Sbjct: 505 SDHVTQNTLEDVPLRPP----EISLTSRSPTDILISWLPIPAKYRRGQVVLYRLSFRLST 560
Query: 845 SNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPG 904
N + V + P + ++GL D+ Y R+ A + G G+ SV +S K
Sbjct: 561 ENS-IQVLELPGTTHEYLLEGLKPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAP 619
Query: 905 LVQDLHVSDSSNSSISLAWREPAEGDPP-SGYILEMRAEDTKEWSKCTKIPISGTCYTVG 963
+LH+ + ++IS+ W++ E GY L + E +E + + YT+
Sbjct: 620 KSPELHLEPLNCTTISVRWQQDVEDTAAIQGYKLYYKEEGQQE-NGPIFLDTKDLLYTLS 678
Query: 964 GLIERQKYFFRIRAVN--------EAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMV 1015
GL R+KY R+ A N + V P + R +PPP P H+
Sbjct: 679 GLDPRRKYHVRLLAYNNIDDGYQADQTVSTPGCVSVRDRMVPPPPPP---------HHLY 729
Query: 1016 VRAGTALCI-----HAAFSGSPPPDVIWQKDGVPTKGRETIT-KSKNHSQFLINSTKRSD 1069
+A T+ I AF+ + + + + V + + + + L+ + +
Sbjct: 730 AKANTSSSIFLHWRRPAFTAAQIINYTIRCNPVGLQNASLVLYLQTSETHMLVQGLEPNT 789
Query: 1070 SGVYRILLQNEFGEARYDIHVRVADFPR----PPTNLRLFEEVPNTVTLTWNHSPDVQED 1125
+ + L + + + V + P PP +++ +T ++W PD E
Sbjct: 790 KYEFAVRLHVDQLSSPWSPVVYHSTLPEAPAGPPVGVKVTLIEDDTALVSWK-PPDGPET 848
Query: 1126 GEAHYIIMKRDASTATWYTAAERVFSNKYTVT-----GLLPGRKYYFRVVARNEIGDSEP 1180
Y I+ AS W +V + +T L+ G Y ++ A NE+G+
Sbjct: 849 VVTRYTILY--ASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGPF 906
Query: 1181 LDSRDTWLINKD 1192
+S + ++ K+
Sbjct: 907 SNSVELAVLPKE 918
Score = 48.5 bits (114), Expect = 4e-05
Identities = 172/901 (19%), Positives = 333/901 (36%), Gaps = 121/901 (13%)
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLE 128
FV++PQ VT D V + G ++W + +G + E+ +I S ++ ++E
Sbjct: 41 FVKEPQDVTVTRKDPVVLDCQAHGEVPIKVTWLK-NGAKMSENKRIEVLSNGSLYISEVE 99
Query: 129 PLTSDDSDN--YKCIASNDHADAI-------------YTVSLLVTEGQEKMDFKKMLK-K 172
+ SD Y+C+A N + + + V + TE E + K
Sbjct: 100 GRRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFEVQPISTEVHEGGVARFACKIS 159
Query: 173 RAPPA-----------PKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDFRGLLR- 220
PPA P + A +L+I + C+ R +
Sbjct: 160 SHPPAVITWEFNRTTLPMTMDRITALPTGVLQIYDVSQRDSGNYRCIAATVAHRRKSMEA 219
Query: 221 --KLKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQ 278
+ K+ I+ ++ T + TVV +C M +P + W +
Sbjct: 220 SLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLEC-MATGNPKPIISWSRLDHK---- 274
Query: 279 YSLGKYDVKQMGTKYMLVISNVNMNDAGIY---SLSVGDKRMS---AELTVLDEPLKFLG 332
S+ ++ + +G L+IS+V + AG+Y + + G + + A LTVL P F+
Sbjct: 275 -SIDVFNTRVLGNG-NLMISDVRLQHAGVYVCRATTPGTRNFTVAMATLTVLAPP-SFVE 331
Query: 333 EMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDA 391
+ + TA F + P W NG+++ + + ++ S+ + + DA
Sbjct: 332 WPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYNSKLVINQIIPEDDA 391
Query: 392 RLSDSGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECE---LTSKDVT 448
E S G+++ +A+LT+ V ++R A ++S +
Sbjct: 392 IYQCMAENS--QGSILSRARLTV-------------VMSEDRPSAPYNVHAETMSSSAIL 436
Query: 449 LRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIV- 507
L W++ YS+ H K L E+ Q+ G + T + D +P Y+ IV
Sbjct: 437 LAWERPLYNSDKVIAYSV-HYMKAEGLNNEEYQVVIGNDTTHYIIDDLEPASNYTFYIVA 495
Query: 508 ------------TVEERLATVKSGMSDVHAATGSPAE-----LCVVLNDEKVEGVWLKDG 550
+ L V ++ + SP + L + + + V +
Sbjct: 496 YMPMGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTDILISWLPIPAKYRRGQVVLYRLS 555
Query: 551 KEITDLPGMQIVK-QGAVHKLIFPSMGPE--HEGKYTFRAKGTESEASVFIADPPTIDPS 607
++ +Q+++ G H+ + + P+ + + T + E+SV+ + S
Sbjct: 556 FRLSTENSIQVLELPGTTHEYLLEGLKPDSVYLVRITAATRVGLGESSVWTSHRTPKATS 615
Query: 608 V---------LEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMER 658
V LE L I+V+ +G L +YK E ++E +
Sbjct: 616 VKAPKSPELHLEPLNCTTISVRWQQDVEDTAAIQGYKL----YYK---EEGQQENGPIFL 668
Query: 659 GEDQALLTISNC-VREDSGLILLKLKN--DHGSATATLH----LSVLDR---PKPPQGRV 708
L T+S R + LL N D A T+ +SV DR P PP +
Sbjct: 669 DTKDLLYTLSGLDPRRKYHVRLLAYNNIDDGYQADQTVSTPGCVSVRDRMVPPPPPPHHL 728
Query: 709 EFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEE 768
+ S + + W+ P + + + + VG ++ + + T+ +E
Sbjct: 729 YAKANTSSSIFLHWRRPAFTAAQ-IINYTIRCNPVGLQNASLVLYLQTSETHMLVQGLEP 787
Query: 769 GKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQD 828
Y+F + ++ + +S P + P P G +VT + + ++W P D
Sbjct: 788 NTKYEFAV-RLHVDQLSSPWSPVVYHSTLPEAPAGPPVGVKVTLIEDDTALVSWKPP--D 844
Query: 829 GGAPVLG----YIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGP 884
G V+ R+ + W ++++ T ++ L+ Y ++ A N+ G
Sbjct: 845 GPETVVTRYTILYASRKAWIAGEWQVLHREGAI-TMALLENLVAGNVYIVKISASNEVGE 903
Query: 885 G 885
G
Sbjct: 904 G 904
Score = 40.4 bits (93), Expect = 0.011
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 7/98 (7%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKI-FYDSINKEHVL 125
P FVE P+ +T P A F + +G P +SW + +G I + +I Y+S L
Sbjct: 327 PSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLK-NGRKIHSNGRIKMYNS-----KL 380
Query: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEK 163
+ + +D Y+C+A N + L V +++
Sbjct: 381 VINQIIPEDDAIYQCMAENSQGSILSRARLTVVMSEDR 418
Score = 34.7 bits (78), Expect = 0.62
Identities = 47/223 (21%), Positives = 78/223 (34%), Gaps = 26/223 (11%)
Query: 1030 GSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKR----SDSGVYRILLQNEFGEA- 1084
G P V W K+G + I N S ++ R SD G Y+ L N++G
Sbjct: 64 GEVPIKVTWLKNGAKMSENKRIEVLSNGSLYISEVEGRRGEQSDEGFYQCLAMNKYGAIL 123
Query: 1085 RYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYI--IMKRDASTATW 1142
H+ ++ + FE P S +V E G A + I + TW
Sbjct: 124 SQKAHLALS-------TISAFEVQPI--------STEVHEGGVARFACKISSHPPAVITW 168
Query: 1143 YTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLK 1202
+ +T L G + V R DS + ++ + + S +
Sbjct: 169 EFNRTTLPMTMDRITALPTGVLQIYDVSQR----DSGNYRCIAATVAHRRKSMEASLTVI 224
Query: 1203 PYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVT 1245
P ++ H P + + T Q + C GNP+P ++
Sbjct: 225 PAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIIS 267
Score = 31.2 bits (69), Expect = 6.9
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)
Query: 1213 PRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVI 1272
P FV + T R C G P P ++ K I +N + ++ V +I
Sbjct: 327 PSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYNSKLVINQII 386
Query: 1273 PTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDK 1308
P +D Y + EN G S LTV +D+
Sbjct: 387 P----EDDAIYQCMAENSQGSILSRARLTVVMSEDR 418
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 120 bits (300), Expect = 1e-26
Identities = 189/842 (22%), Positives = 319/842 (37%), Gaps = 97/842 (11%)
Query: 395 DSGEFSAEA-----GNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDV-T 448
D G + EA G+++ + P++F+S ++V L+CE+ + + T
Sbjct: 111 DEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPT 170
Query: 449 LRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAM-----QDGDPTEYYS 503
+ W+K+ Q L S L I Q D G Y A + G+ E
Sbjct: 171 IHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRI 230
Query: 504 TAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIV 562
+ + +L ++ S+V A G A L C V WL+ G+E+ L +
Sbjct: 231 LSDPGLHRQLYFLQRP-SNVVAIEGKDAVLECCVSGYPPPSFTWLR-GEEVIQLRSKKYS 288
Query: 563 KQGAVHKLIFPSMGPEHEGKYT----FRAKGTESEASVFIADPPTI--DPSVLEALAAHA 616
G + LI ++ + G YT ++ + + A + + PP PS L A +
Sbjct: 289 LLGGSNLLI-SNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMD 347
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
I + GKP+P V W K+G V + + G + +L + V+ D G
Sbjct: 348 I--------EFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGV---VKSDEG 396
Query: 677 LILLKLKNDHGSATATLHLSVLDRPKP-----------PQGRVEFLELSGSCVHMKWKAP 725
+N+ G+A + L V PKP P+ V L +S V + W+ P
Sbjct: 397 FYQCVAENEAGNAQTSAQLIV---PKPAIPSSSVLPSAPRDVVPVL-VSSRFVRLSWRPP 452
Query: 726 KDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVS 785
+ G + F V G + + ++ Y FR++A N G
Sbjct: 453 AEAKGN-IQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPG 511
Query: 786 DPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGS 845
+ + +V ++ PG Q + ++ ITW P G PV GY + + +
Sbjct: 512 ESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANG-PVQGYRLFCTEVST 570
Query: 846 NLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD-PVKPPG 904
+ D G ++GL + TEY R +A N+ GPG + + V D P PP
Sbjct: 571 GKEQNIEVD---GLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPP- 626
Query: 905 LVQDLHVSDSSNSSISLAWREPAEGDPPSGYI--LEMRAEDTKEWSKCTKIPISGTCYTV 962
Q++ + ++ SI ++W P G +G+I ++R T + + + Y
Sbjct: 627 --QNVSLEVVNSRSIKVSWLPPPSG-TQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLF 683
Query: 963 GGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVVRAGTAL 1022
GL + +Y F++ A+ G G P A P S + VR T
Sbjct: 684 TGLEKGSQYSFQVSAMTVNGTGPP---SNWYTAETPENDLDESQVPDQPSSLHVRPQTN- 739
Query: 1023 CIHAAFSGSPPPDVIWQ----KDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
CI +++ P+++ + GV + ET+ + I + S V +
Sbjct: 740 CIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAF 799
Query: 1079 NEFGEA-----------------RYDIHVRVADFPR----------PPTNLRLFEEVPNT 1111
N GE D + + DFP PP ++ +
Sbjct: 800 NNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQAVALTHDA 859
Query: 1112 VTLTW--NHSPDVQEDGEAH-YIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFR 1168
V ++W N P Q+ E Y + R + +A+ +E S YT TGL P Y F
Sbjct: 860 VRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFS 919
Query: 1169 VV 1170
V+
Sbjct: 920 VM 921
Score = 80.9 bits (198), Expect = 8e-15
Identities = 179/831 (21%), Positives = 311/831 (37%), Gaps = 107/831 (12%)
Query: 233 AIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMI-WIKGTEPLRIQYSLGKYDVKQMGT 291
A+R L D T V+ DC E D V +I W K I +LG + KQ +
Sbjct: 39 ALRFLSEPSDAVTMRGGNVLLDCSAE-SDRGVPVIKWKKDG----IHLALGMDERKQQLS 93
Query: 292 KYMLVISNV-----NMNDAGIYSL--SVGDKRMSAELTV---LDEPLKFLGEMKPVKVTE 341
L+I N+ + D G+Y S+GD T + PL+FL + + V
Sbjct: 94 NGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFM 153
Query: 342 RQTAVFEIR-LSKKEPNFVWKFNGKELKR-DDKYEITVSEDGLTHTLKIKDA-----RLS 394
T + + + + P W+ N ++L + V G +++ R S
Sbjct: 154 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCS 213
Query: 395 DSGEFSAEAGNLVQKAQLTIDRI--PIKFVSNLKNVRVKERSRACLECELTS-KDVTLRW 451
S+ GN + L+ + + F+ NV E A LEC ++ + W
Sbjct: 214 ARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTW 273
Query: 452 KKDGQLL-MHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVE 510
+ +++ + KYS+ + L+I + D G YT V + + V V
Sbjct: 274 LRGEEVIQLRSKKYSLLGG---SNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVP 330
Query: 511 ERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGV-WLKDGKEITDLPGMQIVKQGAVHK 569
+ S+++A E ++ + V V W+K+G + QIV +
Sbjct: 331 PWFL---NHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRI 387
Query: 570 LIFPSMGPEHEGKYTFRAKG----TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTA 625
L + EG Y A+ ++ A + + P SVL + + V V +
Sbjct: 388 L---GVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVS-SR 443
Query: 626 HIKVPFRGKPLPK-------VTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLI 678
+++ +R K V + ++G ER LT+ N E
Sbjct: 444 FVRLSWRPPAEAKGNIQTFTVFFSREG---DNRERALNTTQPGSLQLTVGNLKPEAMYTF 500
Query: 679 LLKLKNDHGSATATLHLSVLDRPK----PPQGRVEFLELSGSCVHMKWKAPK-DNGGRPV 733
+ N+ G ++ + V +P+ P ++ + S + + + W+ P NG
Sbjct: 501 RVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQG 560
Query: 734 TQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVN--SEGVSDPLETE 791
+ + GK+ I EVDG ++ +++ Y R LA N GVS T
Sbjct: 561 YRLFCTEVSTGKEQNI---EVDG--LSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITV 615
Query: 792 EVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAP---TQDGGAPVLGYIVERRK------ 842
+ P PP S + V ++ ++W P TQ+G + GY + RK
Sbjct: 616 VTLSDVPSAPPQNVS---LEVVNSRSIKVSWLPPPSGTQNGF--ITGYKIRHRKTTRRGE 670
Query: 843 ----KGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPS------VPSS 892
+ +NLW GL + ++Y F+V A+ G G PS P +
Sbjct: 671 METLEPNNLWY------------LFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPEN 718
Query: 893 SVVAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGD-PPSGYILEMRAEDTKEWSKCT 951
+ D + P LHV +N I ++W P + GYI+ +++
Sbjct: 719 DL---DESQVPDQPSSLHVRPQTNCII-MSWTPPLNPNIVVRGYIIGYGVGSP--YAETV 772
Query: 952 KIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAP 1002
++ Y++ L Y ++A N AG G P+ R++ P P
Sbjct: 773 RVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDP 823
Score = 76.3 bits (186), Expect = 2e-13
Identities = 226/1062 (21%), Positives = 385/1062 (36%), Gaps = 215/1062 (20%)
Query: 17 EFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGDSVPEFVEKPQPV 76
+ S+ + +Q + +E + + +S+ + S+++R++ + + F+ + + V
Sbjct: 91 QLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPL-RFLSQTESV 149
Query: 77 TAPEGDKAVFRARVQGNAKPHISWKRESG--IPIKESAKIFYDSINKEHVLKLEPLTSDD 134
TA GD + + V G P I W++ PI +++ + +L+P D
Sbjct: 150 TAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQP---GD 206
Query: 135 SDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANEKEMLEI 194
Y+C A N PA + NE E+ I
Sbjct: 207 IGIYRCSARN-------------------------------PA----SSRTGNEAEV-RI 230
Query: 195 LSKVPKKDFEKVCMEYGFTDFRGLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVFD 254
LS GL R+L +++ V AI E K+ ++
Sbjct: 231 LSDP------------------GLHRQLYFLQRPSNVVAI------EGKDAVLEC----- 261
Query: 255 CIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGD 314
C+ P+ W++G E ++++ KY + +G +L ISNV +D+G+Y+ V
Sbjct: 262 CVSGYPPPS--FTWLRGEEVIQLRSK--KYSL--LGGSNLL-ISNVTDDDSGMYTCVVTY 314
Query: 315 KR----MSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKE-PNFVWKFNGKELKR 369
K SAELTVL P FL + E FE +S K P W NG +
Sbjct: 315 KNENISASAELTVLVPPW-FLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIP 373
Query: 370 DDKYEITVSEDGLTHTLKIKDARLSDSGEFSA----EAGNLVQKAQLTIDRIPIKFVSNL 425
D ++I + L+I SD G + EAGN AQL + + I S L
Sbjct: 374 SDYFQIVGGSN-----LRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVL 428
Query: 426 KNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSM--NHEGKRAELIIEDAQ-- 481
+ R + ++S+ V L W+ + + +++ + EG E + Q
Sbjct: 429 PSA-----PRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPG 483
Query: 482 --------LSDGGEYT--VVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPA 531
L YT VVA + P E V + L V + ++ A + SP
Sbjct: 484 SLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQ-VPGPVENLQAVSTSPT 542
Query: 532 ELCVVLN-----DEKVEGVWL-----KDGKEIT--------DLPGMQIVKQGAVHKLIFP 573
+ + + V+G L GKE L G++ + ++ L +
Sbjct: 543 SILITWEPPAYANGPVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYN 602
Query: 574 SMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRG 633
GP T+ V ++D P+ P ++++V ++ IKV +
Sbjct: 603 RYGP---------GVSTDDITVVTLSDVPSAPPQ--------NVSLEVVNSRSIKVSWLP 645
Query: 634 KPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSA---- 689
P + G ++ R + RGE + L E + L L + GS
Sbjct: 646 PPSGTQNGFITGYKI--RHRKTTRRGEMETL--------EPNNLWYLFTGLEKGSQYSFQ 695
Query: 690 ----------------TATLHLSVLDRPK-PPQGRVEFLELSGSCVHMKWKAPKDNGGRP 732
TA + LD + P Q + +C+ M W P N
Sbjct: 696 VSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCIIMSWTPPL-NPNIV 754
Query: 733 VTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNS--EGV------ 784
V +I+ VG + + VD K +S ++E Y + A N+ EGV
Sbjct: 755 VRGYIIGY-GVGSP-YAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESA 812
Query: 785 --------SDPLETEEVFAGNPIEPPGFASQP------QVTDVTKEAVTITW---NAPTQ 827
+DP++ + P P ++ Q +T +AV ++W + P
Sbjct: 813 TTRSITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKN 872
Query: 828 DGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQP 887
+ V Y V R S + T GL +T YEF V+
Sbjct: 873 QKTSEVRLYTVRWRTSFSAS-AKYKSEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTW 931
Query: 888 SVPSSSVVAKDPVKPPGLVQDLHV--SDSSNSSISLAWREPAEGDPP-SGYILEMRAEDT 944
S+ + + + P +DL V + ++ ++W+ P E + + YIL +
Sbjct: 932 SMTAHATTYE--AAPTSAPKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKN 989
Query: 945 KEWSKCTKIPISGTCYT--VGGLIERQKYFFRIRAVNEAGVG 984
ISG T + L Y+FRI+A N GVG
Sbjct: 990 IPIDDWIMETISGDRLTHQIMDLNLDTMYYFRIQARNSKGVG 1031
Score = 71.6 bits (174), Expect = 5e-12
Identities = 143/654 (21%), Positives = 246/654 (37%), Gaps = 86/654 (13%)
Query: 616 AITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDS 675
++T +G T +K G+P+P + W K+ ++T S L IS D
Sbjct: 148 SVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDI 207
Query: 676 GLILLKLKNDHGSATAT-LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVT 734
G+ +N S T + +L P + ++ FL+ + V ++ G V
Sbjct: 208 GIYRCSARNPASSRTGNEAEVRILSDPGLHR-QLYFLQRPSNVVAIE-------GKDAVL 259
Query: 735 QFIVERRAVGKKSWIKIGEVD----------GKVTNFSTNKVEEGKAYQFRILAVNSEGV 784
+ V +W++ EV G +N ++ ++ +E +
Sbjct: 260 ECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENI 319
Query: 785 SDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKG 844
S E + PP F + P E++ I + P + ++ K
Sbjct: 320 SASAEL------TVLVPPWFLNHPSNL-YAYESMDIEFECTVSGKPVPTVNWM-----KN 367
Query: 845 SNLWVPVNKDPIQG-TKCTVDGLLEDTEYEFRVIAVNKAGPGQ---------PSVPSSSV 894
++ +P + I G + + G+++ E ++ +A N+AG Q P++PSSSV
Sbjct: 368 GDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSV 427
Query: 895 VAKDPVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTK 952
+ P P +V L S+ + L+WR PAE G+ + + R D +E + T
Sbjct: 428 L---PSAPRDVVPVL----VSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTT 480
Query: 953 IPISGTCYTVGGLIERQKYFFRIRAVNEAGVGE---PVELDKGVRAMPPPAAPKFDLSAR 1009
P S TVG L Y FR+ A NE G GE P+++ P P +L A
Sbjct: 481 QPGS-LQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVP--GPVENLQA- 536
Query: 1010 LKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQ-----FLINS 1064
V + T++ I + PP G E T + + + + +
Sbjct: 537 -----VSTSPTSILI----TWEPPAYANGPVQGYRLFCTEVSTGKEQNIEVDGLSYKLEG 587
Query: 1065 TKRSDSGVYRILLQNEFGE--ARYDIHV-RVADFPR-PPTNLRLFEEVPNTVTLTWNHSP 1120
K+ R L N +G + DI V ++D P PP N+ L ++ ++W P
Sbjct: 588 LKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPP 647
Query: 1121 DVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEP 1180
++G ++ +T + Y TGL G +Y F+V A G P
Sbjct: 648 SGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPP 707
Query: 1181 LDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPR-------FVTPLKPHTVLRG 1227
W + DL P + P+ + PL P+ V+RG
Sbjct: 708 ----SNWYTAETPENDLDESQVPDQPSSLHVRPQTNCIIMSWTPPLNPNIVVRG 757
Score = 37.0 bits (84), Expect = 0.13
Identities = 65/293 (22%), Positives = 99/293 (33%), Gaps = 38/293 (12%)
Query: 1019 GTALCIHAAFSGSPPPDVIWQKDG-----VPTKGRETITKSKNHSQFLINSTKRSDSGVY 1073
G + + G P P + WQK+ +P R + S I+ + D G+Y
Sbjct: 154 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPS---GALQISRLQPGDIGIY 210
Query: 1074 RILLQNEFGEAR-YDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYII 1132
R +N + VR+ P L + N V + +D +
Sbjct: 211 RCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEG-------KDAVLECCV 263
Query: 1133 MKRDASTATWYTAAE--RVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLIN 1190
+ TW E ++ S KY++ G G V ++ G + +
Sbjct: 264 SGYPPPSFTWLRGEEVIQLRSKKYSLLG---GSNLLISNVTDDDSGMYTCV------VTY 314
Query: 1191 KDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYK-G 1249
K++ SA+L P F+ D C G P PTV K G
Sbjct: 315 KNENISASAELTVLVP------PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNG 368
Query: 1250 DVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
DV I ++ Y G L I D G Y + ENE G ++S L V
Sbjct: 369 DVVIPSD----YFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIV 417
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 119 bits (299), Expect = 1e-26
Identities = 153/672 (22%), Positives = 263/672 (39%), Gaps = 96/672 (14%)
Query: 286 VKQMGTKYMLVISNVNMNDAGIYSLSVGD-KRMSAELTVLDE---PLKFLGEMKPVKVTE 341
V++ G + L I N N+ DAGIY D K + E TV+ E L F + P + +
Sbjct: 69 VQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQ 128
Query: 342 RQTAVFEIRLSKKE-PNFVWKFNGKELKR--DDKYEITVSEDGLTHTLKIKDARLSDSGE 398
+ A R+S P W ++ +E+ D+++ + + + L+I + SD G
Sbjct: 129 GEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNN-----LQILNINKSDEGI 183
Query: 399 FSAEA-----GNLVQKAQLTIDRIP--IKFVSNLKNVRVKERSRACLECELT-SKDVTLR 450
+ E G + + + I +P I N + C + S + +
Sbjct: 184 YRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAIS 243
Query: 451 WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVE 510
W ++G+L+ KY + +G EL + + SDGG Y A E + V V+
Sbjct: 244 WFRNGKLIEENEKYIL--KGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQ 301
Query: 511 ERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKL 570
+ +K+ + G +C + E W + AV
Sbjct: 302 PHIIQLKN---ETTYENGQVTLVCDAEGEPIPEITWKR-----------------AVDGF 341
Query: 571 IFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAI------------- 617
F +G+ KG +S+ I D D + AA I
Sbjct: 342 TFTEGDKSLDGR--IEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEY 399
Query: 618 --------TVKV---GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGED--QAL 664
T+ G+ +I + P + W +D + + + +++ + +
Sbjct: 400 APKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMI 459
Query: 665 LTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKA 724
L I+ D G N G+ L++ D P P G V+ +ELS + + +
Sbjct: 460 LEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYG-VKIIELSQTTAKVSFNK 518
Query: 725 PKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGV 784
P +GG P+ + V+ + V + W KI G T N +E Y+ R+ AVN +G
Sbjct: 519 PDSHGGVPIHHYQVDVKEVASEIW-KIVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQ 577
Query: 785 SDPLETEEVFAGNPIE---PPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERR 841
D + E +F P+ PP QP K ++T DGGAP+L YIV+ R
Sbjct: 578 GDYSKIE-IFQTLPVREPSPPSIHGQPSSGKSFKLSIT-----KQDDGGAPILEYIVKYR 631
Query: 842 KKGS-NLWVPVNKDPIQGTKCTVDGLLEDTE----YEFRVIAVNKAGPGQPSVPSSSVVA 896
K + W+ + +QG K + +LE + YE ++ A N+ G +P+V S+
Sbjct: 632 SKDKEDQWL---EKKVQGNKDHI--ILEHLQWTMGYEVQITAANRLGYSEPTVYEFSMPP 686
Query: 897 KDPVKPPGLVQD 908
K P +++D
Sbjct: 687 K-----PNIIKD 693
Score = 79.0 bits (193), Expect = 3e-14
Identities = 141/684 (20%), Positives = 267/684 (39%), Gaps = 84/684 (12%)
Query: 355 EPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL---VQKAQ 411
EP + +N + K + V ++G+ L I +A + D+G + +A + Q+A
Sbjct: 47 EPESIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEAT 106
Query: 412 LTIDRIP-IKFVSNLKNVRVKERSRACLECELTSKDV-TLRWKKDGQLLMHGTKYSMNHE 469
+ ++ + F + K+ A + C ++S + W L H + + +
Sbjct: 107 VVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSW------LYHNEEVTTISD 160
Query: 470 GKRAELIIEDAQL-----SDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524
+ A L + Q+ SD G Y + + IV V A + +
Sbjct: 161 NRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPA-ISMPQKSFN 219
Query: 525 AATGSPAEL---CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEG 581
A E+ C + W ++GK I + + + +G+ +L ++ G
Sbjct: 220 ATAERGEEMTFSCRASGSPEPAISWFRNGKLIEE--NEKYILKGSNTELTVRNIINSDGG 277
Query: 582 KYTFRA--KGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKV 639
Y RA K E E F+ + P +++ + T + G + G+P+P++
Sbjct: 278 PYVCRATNKAGEDEKQAFLQ--VFVQPHIIQL--KNETTYENGQVTLV-CDAEGEPIPEI 332
Query: 640 TWYK--DGMEVTEEE-----RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
TW + DG TE + R+ ++ + L I + DSG + + G +
Sbjct: 333 TWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKS 392
Query: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMK------------WKAPKDNGGRPVTQFI-VE 739
++L + PK + + G+ +++ W+ +D P ++
Sbjct: 393 MYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWR--RDKLVLPAKNTTNLK 450
Query: 740 RRAVGKKSWIKIGEVD----GKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFA 795
+ G+K ++I G+ +TN + G +Q ILA+ A
Sbjct: 451 TYSTGRKMILEIAPTSDNDFGRYNCTATNHI--GTRFQEYILAL---------------A 493
Query: 796 GNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDP 855
P P G ++ ++++ +++N P GG P+ Y V+ ++ S +W V
Sbjct: 494 DVPSSPYGV----KIIELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVASEIWKIVRSHG 549
Query: 856 IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSS 915
+Q T ++ L +T YE RV AVN G GQ + PV+ P +H SS
Sbjct: 550 VQ-TMVVLNNLEPNTTYEIRVAAVN--GKGQGDYSKIEIFQTLPVREPS-PPSIHGQPSS 605
Query: 916 NSSISLAWREPAEGDPP-SGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFR 974
S L+ + +G P YI++ R++D ++ K+ + + L Y +
Sbjct: 606 GKSFKLSITKQDDGGAPILEYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQWTMGYEVQ 665
Query: 975 IRAVNEAGVGEPVELDKGVRAMPP 998
I A N G EP + +MPP
Sbjct: 666 ITAANRLGYSEPTVYE---FSMPP 686
Score = 37.7 bits (86), Expect = 0.074
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGD 1282
T RG++ T +C G+P P ++ ++ I N K+ ++ L + D G
Sbjct: 221 TAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSN--TELTVRNIINSDGGP 278
Query: 1283 YSVLVENELGKDRSSCTLTVY 1303
Y N+ G+D L V+
Sbjct: 279 YVCRATNKAGEDEKQAFLQVF 299
Score = 36.6 bits (83), Expect = 0.16
Identities = 19/79 (24%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGI-PIKESAKIFYDSINKEHVL 125
P+F+ + EG+ V+ N I W+R+ + P K + + S ++ +L
Sbjct: 401 PKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMIL 460
Query: 126 KLEPLTSDDSDNYKCIASN 144
++ P + +D Y C A+N
Sbjct: 461 EIAPTSDNDFGRYNCTATN 479
Score = 36.2 bits (82), Expect = 0.21
Identities = 62/315 (19%), Positives = 114/315 (36%), Gaps = 36/315 (11%)
Query: 1019 GTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
G + SGSP P + W ++G + E ++++ + + SD G Y
Sbjct: 225 GEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRAT 284
Query: 1079 NEFGEARYDIHVRVADFPRPPTNLRLFEEVP---NTVTLTWNHSPDVQEDGEAHYIIMKR 1135
N+ GE ++V F +P ++L E VTL +GE I +
Sbjct: 285 NKAGEDEKQAFLQV--FVQPHI-IQLKNETTYENGQVTLV------CDAEGEPIPEITWK 335
Query: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQ 1195
A +T ++ + V G + + V ++ DS D
Sbjct: 336 RAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDV---KLSDSGRYDC------------ 380
Query: 1196 DLSAKLKPYEKK---DWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVN 1252
+ ++++ ++K D +AP+F++ + G ++C NP ++ + +
Sbjct: 381 EAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLV 440
Query: 1253 I----TANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDK 1308
+ T N K + ST L I + D G Y+ N +G L + D
Sbjct: 441 LPAKNTTNLKTY--STGRKMILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSS 498
Query: 1309 SVVASITESLQKKSK 1323
I E Q +K
Sbjct: 499 PYGVKIIELSQTTAK 513
Score = 35.0 bits (79), Expect = 0.48
Identities = 65/291 (22%), Positives = 103/291 (35%), Gaps = 49/291 (16%)
Query: 1029 SGSPPPDVIW--QKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARY 1086
S SP P V W + V T N++ ++N K SD G+YR EAR
Sbjct: 139 SSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINK-SDEGIYRC---EGRVEARG 194
Query: 1087 DIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDAS---TATWY 1143
+I R ++ + VP +++ E GE + S +W+
Sbjct: 195 EIDFR---------DIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWF 245
Query: 1144 TAAERVFSN-KYTVTGLLPGRKYYFRVVARNEIG-DSEPLDSRDTWLINKDQIQD-LSAK 1200
+ + N KY + G + RN I D P R T +D+ Q L
Sbjct: 246 RNGKLIEENEKYILKGSNT------ELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVF 299
Query: 1201 LKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTV---------TLYKGDV 1251
++P+ + LK T T+ C G P P + T +GD
Sbjct: 300 VQPH-----------IIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDK 348
Query: 1252 NITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302
++ + + G +L I L DSG Y + +G + S L +
Sbjct: 349 SL--DGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDI 397
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 112 bits (280), Expect = 2e-24
Identities = 161/677 (23%), Positives = 271/677 (40%), Gaps = 80/677 (11%)
Query: 352 SKKEPNFVWKFNGK--ELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA-----G 404
S+ P WK +G L DD+ ++ + D G + A G
Sbjct: 78 SEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLG 137
Query: 405 NLVQK-AQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVT-LRWKKDGQLLMHGT 462
++ + A+L + +P +F S + V + A L CE+ + V +RW+++ Q L+
Sbjct: 138 TIISRTAKLIVAGLP-RFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDD 196
Query: 463 KYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSD 522
+ G L+I +A DGG Y V ++ G P +Y VE ++ +SD
Sbjct: 197 RVIKLPSGM---LVISNATEGDGGLYRCV-VESGGPPKYSDE----VELKVLPDPEVISD 248
Query: 523 VHAATGSPAELCVVLNDEKV-----EGV------WLKDGKEITDLPGMQIVKQGAVHKLI 571
+ P+ L V+ + V G+ W+K+ +E D + + A L
Sbjct: 249 L-VFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKN-EEALDTESSERLVLLAGGSLE 306
Query: 572 FPSMGPEHEGKYTFRAKG----TESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHI 627
+ + G Y A E++A + + P A ++ +
Sbjct: 307 ISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIV------F 360
Query: 628 KVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG 687
+ GKP P V W K+G V + + + + L + V+ D G +ND G
Sbjct: 361 ECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHN---LQVLGLVKSDEGFYQCIAENDVG 417
Query: 688 SATATLHLSVLDR--------PKPPQGRVEFLELSGSCVHMKWKAP-KDNGGRPVTQFI- 737
+A A L +L+ P P+ V L +S + + W+ P D G +T +
Sbjct: 418 NAQAGAQLIILEHAPATTGPLPSAPRDVVASL-VSTRFIKLTWRTPASDPHGDNLTYSVF 476
Query: 738 -----VERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE 792
+ R V S GE+ + N V Y FR++A N G +
Sbjct: 477 YTKEGIARERVENTS--HPGEMQVTIQNLMPATV-----YIFRVMAQNKHGSGESSAPLR 529
Query: 793 VFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVN 852
V ++ PG A + + ++T+TW P G + Y + +KG++ V+
Sbjct: 530 VETQPEVQLPGPAPNLRAYAASPTSITVTWETPVS-GNGEIQNYKLYYMEKGTDKEQDVD 588
Query: 853 KDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVS 912
+ T++GL + TEY FRV+A NK GPG S P +V V P Q+L +
Sbjct: 589 ---VSSHSYTINGLKKYTEYSFRVVAYNKHGPG-VSTPDVAVRTLSDV-PSAAPQNLSLE 643
Query: 913 DSSNSSISLAWREPA---EGDPPSGYILEMRAEDTKEWSKCTKIPISGT--CYTVGGLIE 967
++ SI + W+ PA + +GY + R K S T+ +SGT + GL
Sbjct: 644 VRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRK--SDVTETLVSGTQLSQLIEGLDR 701
Query: 968 RQKYFFRIRAVNEAGVG 984
+Y FR+ A+ G G
Sbjct: 702 GTEYNFRVAALTINGTG 718
Score = 71.6 bits (174), Expect = 5e-12
Identities = 158/714 (22%), Positives = 261/714 (36%), Gaps = 124/714 (17%)
Query: 294 MLVISNVNMNDAGIYSLSV---GDKRMS--AELTVLDEP-----LKFLGEMKP-VKVTER 342
MLVISN D G+Y V G + S EL VL +P L FL + P V+V +
Sbjct: 205 MLVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQ 264
Query: 343 QTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAE 402
+ + P W N + L + + + G +L+I D D+G +
Sbjct: 265 DVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG---SLEISDVTEDDAGTYFCI 321
Query: 403 AGN----LVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDV-TLRWKKDGQL 457
A N + +A+LT+ P +F+ N+ E ECE+T K T++W K+G +
Sbjct: 322 ADNGNETIEAQAELTVQAQP-EFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDM 380
Query: 458 LMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLAT-- 515
++ + + K L + SD G Y +A D + ++ +E AT
Sbjct: 381 VIPSDYFKI---VKEHNLQVLGLVKSDEGFYQCIAENDVGNAQ-AGAQLIILEHAPATTG 436
Query: 516 -VKSGMSDVHAATGSPAELCVV----LNDEKVEGV-----WLKDG-----KEITDLPG-M 559
+ S DV A+ S + + +D + + + K+G E T PG M
Sbjct: 437 PLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEM 496
Query: 560 QIVKQGAVHK--LIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTID-PSVLEALAAHA 616
Q+ Q + IF M G ES A + + P + P L A+A
Sbjct: 497 QVTIQNLMPATVYIFRVMAQNKHG-------SGESSAPLRVETQPEVQLPGPAPNLRAYA 549
Query: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQA--------LLTIS 668
+ T + P G E+ + ME+G D+ TI+
Sbjct: 550 AS-PTSITVTWETPVSGNG-----------EIQNYKLYYMEKGTDKEQDVDVSSHSYTIN 597
Query: 669 NCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLEL-----SGSCVHMKWK 723
+ + N HG +T ++V P + L L +H +
Sbjct: 598 GLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPP 657
Query: 724 APKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRI--LAVNS 781
AP G+ +T + + R +KS + V G + ++ G Y FR+ L +N
Sbjct: 658 APATQNGQ-ITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTING 716
Query: 782 EGVSDPLETEEVFAGN------PIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLG 835
G + + E F + P P +P VT ++ ++W P ++ V G
Sbjct: 717 TGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVT-----SIVVSW-TPPENQNIVVRG 770
Query: 836 YIVERRKKGSNLWVP---VNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQP----- 887
Y + G + P K + T++ L + Y + A N G G P
Sbjct: 771 YAI-----GYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESA 825
Query: 888 ----------------SVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSISLAWRE 925
+ P + V P+ PP VQ S S+ +I + W +
Sbjct: 826 VTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQ---ASILSHDTIRITWAD 876
Score = 55.1 bits (131), Expect = 4e-07
Identities = 56/224 (25%), Positives = 95/224 (42%), Gaps = 17/224 (7%)
Query: 964 GLIERQKYFFRIRAVNEAGVGEP----VELDKGVRAMPP-PAAPKFDLSARLKSHMVVRA 1018
GL++ + F++ A N+ G + + L+ P P+AP+ D+ A L S ++
Sbjct: 399 GLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPR-DVVASLVSTRFIKL 457
Query: 1019 GTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ 1078
+ V + K+G+ + E T Q I + + ++R++ Q
Sbjct: 458 TWRTPASDPHGDNLTYSVFYTKEGIARERVEN-TSHPGEMQVTIQNLMPATVYIFRVMAQ 516
Query: 1079 NEFGEARYDIHVRV-----ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEA-HYII 1132
N+ G +RV P P NLR + P ++T+TW V +GE +Y +
Sbjct: 517 NKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWE--TPVSGNGEIQNYKL 574
Query: 1133 MKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIG 1176
+ T V S+ YT+ GL +Y FRVVA N+ G
Sbjct: 575 YYMEKGTDKEQDVD--VSSHSYTINGLKKYTEYSFRVVAYNKHG 616
Score = 51.6 bits (122), Expect = 5e-06
Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 4/93 (4%)
Query: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLK 126
PEF+++P + A E VF V G P + W + + I Y I KEH L+
Sbjct: 341 PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSD----YFKIVKEHNLQ 396
Query: 127 LEPLTSDDSDNYKCIASNDHADAIYTVSLLVTE 159
+ L D Y+CIA ND +A L++ E
Sbjct: 397 VLGLVKSDEGFYQCIAENDVGNAQAGAQLIILE 429
Score = 45.4 bits (106), Expect = 4e-04
Identities = 37/160 (23%), Positives = 63/160 (39%), Gaps = 10/160 (6%)
Query: 1029 SGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDI 1088
+G P P V W K+G + K H+ ++ K SD G Y+ + +N+ G A+
Sbjct: 365 TGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVK-SDEGFYQCIAENDVGNAQAGA 423
Query: 1089 ------HVRVADFPRPPTNLRLFEEVPNT--VTLTWNH-SPDVQEDGEAHYIIMKRDAST 1139
H P P + + +T + LTW + D D + + ++
Sbjct: 424 QLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIA 483
Query: 1140 ATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
+ T+ L+P Y FRV+A+N+ G E
Sbjct: 484 RERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGE 523
Score = 38.1 bits (87), Expect = 0.056
Identities = 48/219 (21%), Positives = 90/219 (41%), Gaps = 33/219 (15%)
Query: 976 RAVNEAGVGEPVELDK-GVRAMPPPAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPP 1034
R V E+G G P D+ ++ +P P + + S +V G + + SG P P
Sbjct: 220 RCVVESG-GPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTP 278
Query: 1035 DVIWQK--DGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQ--NEFGEARYDIHV 1090
+ W K + + T+ E + S I+ D+G Y + NE EA+ ++ V
Sbjct: 279 TIKWMKNEEALDTESSERLVLLAGGS-LEISDVTEDDAGTYFCIADNGNETIEAQAELTV 337
Query: 1091 RV-ADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERV 1149
+ +F + PTN+ E S D+ + E + + T W + V
Sbjct: 338 QAQPEFLKQPTNIYAHE------------SMDIVFECE----VTGKPTPTVKWVKNGDMV 381
Query: 1150 FSNKY---------TVTGLLPGRKYYFRVVARNEIGDSE 1179
+ Y V GL+ + +++ +A N++G+++
Sbjct: 382 IPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQ 420
Score = 36.6 bits (83), Expect = 0.16
Identities = 64/297 (21%), Positives = 113/297 (38%), Gaps = 38/297 (12%)
Query: 1016 VRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075
V AG ++ + P V W+++ P + + K + + N+T+ D G+YR
Sbjct: 163 VYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATE-GDGGLYRC 221
Query: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135
++++ G +Y V + P P EV + + SP V+ G+ +++
Sbjct: 222 VVESG-GPPKYSDEVELKVLPDP--------EVISDLVFLKQPSPLVRVIGQD--VVLPC 270
Query: 1136 DAS-----TATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLI- 1189
AS T W E + + LL G EI D D+ + I
Sbjct: 271 VASGLPTPTIKWMKNEEALDTESSERLVLLAGGSL--------EISDVTEDDAGTYFCIA 322
Query: 1190 -NKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYK 1248
N ++ + A+L + ++ P T + H D C G P PTV K
Sbjct: 323 DNGNETIEAQAELTVQAQPEFLKQP---TNIYAH---ESMDIVFECEVTGKPTPTVKWVK 376
Query: 1249 -GDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYD 1304
GD+ I ++ Y L + D G Y + EN++G ++ L + +
Sbjct: 377 NGDMVIPSD----YFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILE 429
Score = 35.4 bits (80), Expect = 0.37
Identities = 62/264 (23%), Positives = 100/264 (37%), Gaps = 40/264 (15%)
Query: 753 EVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPL----------ETEEV--FAGN--- 797
+VD K ++ ++ Y + A N+ G PL +T EV F N
Sbjct: 786 KVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPY 845
Query: 798 -PIEPPGFASQP---QVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW---VP 850
P+ P P Q + ++ + + ITW D P I + R W +P
Sbjct: 846 TPVPDPTPMMPPVGVQASILSHDTIRITW----ADNSLPKHQKITDSRYYTVR-WKTNIP 900
Query: 851 VNKDPIQGTKCT----VDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAK-DPVKPPGL 905
N T V GL +T YEF V+ S+ + + P PP
Sbjct: 901 ANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPP-- 958
Query: 906 VQDLHV--SDSSNSSISLAWREPAEGDPP-SGYILEMRAEDTKEWSKCTKIPISGTCYT- 961
+D+ V + +I + W+ P+E + +GYI+ + E P+ G T
Sbjct: 959 -KDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTH 1017
Query: 962 -VGGLIERQKYFFRIRAVNEAGVG 984
+ L Y+F+I+A N G+G
Sbjct: 1018 QIQELTLDTPYYFKIQARNSKGMG 1041
Score = 34.3 bits (77), Expect = 0.82
Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 4/77 (5%)
Query: 69 FVEKPQPVTAPEGDKAVFRARVQGNAKPHISW-KRESGIPIKESAKIFYDSINKEHVLKL 127
F+++P P+ G V G P I W K E + + S ++ + L++
Sbjct: 251 FLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS---LEI 307
Query: 128 EPLTSDDSDNYKCIASN 144
+T DD+ Y CIA N
Sbjct: 308 SDVTEDDAGTYFCIADN 324
Score = 31.6 bits (70), Expect = 5.3
Identities = 17/93 (18%), Positives = 41/93 (44%), Gaps = 5/93 (5%)
Query: 52 SLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKES 111
++++R++ + +P F +P+P + G+ A+ V + P + W++ + +
Sbjct: 138 TIISRTAKLIVA-GLPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDD 196
Query: 112 AKIFYDSINKEHVLKLEPLTSDDSDNYKCIASN 144
I S +L + T D Y+C+ +
Sbjct: 197 RVIKLPS----GMLVISNATEGDGGLYRCVVES 225
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 109 bits (273), Expect = 2e-23
Identities = 185/840 (22%), Positives = 319/840 (37%), Gaps = 115/840 (13%)
Query: 240 LEDKETKVDTTV--------VFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGT 291
+ED ETK +TV V C ++ W PL +Q ++ ++ G
Sbjct: 121 IEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGN 180
Query: 292 KYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLK-----FLGEMKP---------V 337
Y I+ V +D G Y+ + +K + PL +GE +P +
Sbjct: 181 LY---IAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETI 237
Query: 338 KVTERQTAVFE-IRLSKKEPNFVWK-FNGKELKRDDKYEITVSEDGLTHTLKIKDARLSD 395
+ + + E L P+ W+ +G L KY + + L+I + + D
Sbjct: 238 QAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQA------ILEIPNFQQED 291
Query: 396 SGEFSAEAGNL----VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSK-DVTLR 450
G + A NL + K QL I P ++ ++N + EC+ + K +
Sbjct: 292 EGFYECIASNLRGRNLAKGQL-IFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYT 350
Query: 451 WKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVE 510
W K+G+ L + + + LII +SD G Y A Y E
Sbjct: 351 WLKNGERLNPEERIQIEN----GTLIITMLNVSDSGVYQCAAENK------YQIIYANAE 400
Query: 511 ERLATVKSGMSDVHAATGSPAEL-------CVVLNDEKVEGVWLKDGKEITDLPGMQIVK 563
R+ S S ++ C + W + + + + +++
Sbjct: 401 LRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLE 460
Query: 564 QGAVHKLIFPSMGPEHEGKYTF-------RAKGTES----EASVFIADPPTIDPSVLEAL 612
G+ L ++ G YT AK T S E +V P +D +V E++
Sbjct: 461 DGS---LKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESI 517
Query: 613 AAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVS-MER--GEDQALLTISN 669
+ +V H I+V F W+ +G + ++ V+ ER GE L I N
Sbjct: 518 V---LPCQVSHDPSIEVVF--------VWFFNGDVIDLKKGVAHFERIGGESVGDLMIRN 566
Query: 670 CVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNG 729
SG L ++ S +A + V P PP+ V+ ++S + + W+A DN
Sbjct: 567 IQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPED-VQVEDISSTTSQLSWRAGPDNN 625
Query: 730 GRPVTQFIVERRAVGKKSWIKIGEV----DGKVTNFSTNKVEEGKAYQFRILAVNSEGVS 785
P+ F ++ R W + V +GK N + + Y+FR++A NS G+
Sbjct: 626 S-PIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIG 684
Query: 786 DPLETEEVFAGNPIEPPGFASQPQVTDV-------TKEAVTITWNA-PTQDGGAPVLGYI 837
+P E E+ AS P V V ++ + ITW + P + GYI
Sbjct: 685 EPSEPSELLRTK-------ASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYI 737
Query: 838 VERRKKGSNLWVPVNKDPIQGTKCTV--DGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVV 895
+ R GS W ++ ++ + ++ + +E +V N G G S+ + ++V
Sbjct: 738 IMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEG--SLSTVTIV 795
Query: 896 AKDPVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPS---GYILEMRAEDTKEWSKCTK 952
+P + + S S + ++W A GY + +D+KE S K
Sbjct: 796 YSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKE-SMIGK 854
Query: 953 IPISG--TCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARL 1010
I +SG T + GL YF +RA N AG G PP+ P +++ +L
Sbjct: 855 IRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKL 914
Score = 78.2 bits (191), Expect = 5e-14
Identities = 165/732 (22%), Positives = 265/732 (36%), Gaps = 116/732 (15%)
Query: 335 KPVKVTERQTAVFEIRLSKKE------------PNFVWKFNGKELKRDDKYEITVSEDGL 382
+P+ E +F + LSK E P++ WK NG ++ Y + L
Sbjct: 25 RPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSL 84
Query: 383 THTLKIKDARLSDSGEFSAEAGNLV-----QKAQLTIDRIPIKFVSNLKNVRVKERSRAC 437
D D G + A NL+ +KA+L I V V+E
Sbjct: 85 AINSPHTD---QDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVV 141
Query: 438 LECELTSK--DVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQ- 494
L C D++ W + L + L I + SD G YT
Sbjct: 142 LLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNK 201
Query: 495 ------DGDPTEYYSTAIVTVEERLATVKSGMSD-VHAATGSPAEL-CVVLNDEKVEGVW 546
G PT + E ++ + + AA S +L C L + + W
Sbjct: 202 EAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISW 261
Query: 547 LK-DGKEITDLPG-MQIVKQGAVHKLIFPSMGPEHEGKY-----TFRAKGTESEASVFIA 599
+ DG + LPG ++ K A+ L P+ E EG Y R + +F A
Sbjct: 262 RRLDG---SPLPGKVKYSKSQAI--LEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYA 316
Query: 600 DPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERG 659
PP + + + + + GKP P TW K+G + EER+ +E G
Sbjct: 317 -PPEWEQKIQNT------HLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENG 369
Query: 660 EDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVL----DRPKPPQGRVEFLELSG 715
++T+ N DSG+ +N + A L VL D K P + F+++ G
Sbjct: 370 --TLIITMLNV--SDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGG 425
Query: 716 SCV-----------HMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTN 764
V + WK + + F++E DG + ++
Sbjct: 426 DIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLE---------------DGSLKIYNIT 470
Query: 765 KVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNA 824
+ + G + +A N G + + V I P P DVT +
Sbjct: 471 RSDAG---SYTCIATNQFGTAKNTGSLIVKERTVITVP-----PSKMDVTVGESIVLPCQ 522
Query: 825 PTQDGGAPVL------GYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
+ D V+ G +++ KKG + + + + L +Y V
Sbjct: 523 VSHDPSIEVVFVWFFNGDVID-LKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTV-- 579
Query: 879 VNKAGPGQPSVPSSSVVAKDPVK-PPGLVQDLHVSDSSNSSISLAWRE-PAEGDPPSGYI 936
Q ++ S S VA V+ PPG +D+ V D S+++ L+WR P P +
Sbjct: 580 -------QTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFT 632
Query: 937 LEMRAEDTKEWSKCTKIP--ISGTCY--TVGGLIERQKYFFRIRAVNEAGVGEPVELDKG 992
++ R + W +P ++G Y TV GL +Y FR+ A N G+GEP E +
Sbjct: 633 IQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSEL 692
Query: 993 VR--AMPPPAAP 1002
+R A P AP
Sbjct: 693 LRTKASVPVVAP 704
Score = 47.4 bits (111), Expect = 9e-05
Identities = 72/293 (24%), Positives = 109/293 (37%), Gaps = 22/293 (7%)
Query: 1035 DVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVAD 1094
DVI K GV R ++ +I + + SG Y +Q + V
Sbjct: 540 DVIDLKKGVAHFER---IGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRG 596
Query: 1095 FPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAE--RVFSN 1152
P PP ++++ + T L+W PD + + I R + W A + +
Sbjct: 597 PPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQI-FTIQTRTPFSVGWQAVATVPEILNG 655
Query: 1153 KY---TVTGLLPGRKYYFRVVARNEIGDSEPLDSRDTWLINKDQIQDLSAKLKPYEKKDW 1209
K TV GL P +Y FRVVA N IG EP S + L+ + A + +
Sbjct: 656 KTYNATVVGLSPWVEYEFRVVAGNSIGIGEP--SEPSELLRTKASVPVVAPVNIHGGGGS 713
Query: 1210 RHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCT 1269
R P + G+ F P + T K V+ +S+F Y + S
Sbjct: 714 RSELVITWESIPEELQNGEGFGYIIMF--RPVGSTTWSKEKVSSVESSRFVYRNES---- 767
Query: 1270 LVIPTCTLKDSGDYSVLVENELGKDRSSCTLTVYDKDDKSVVASITESLQKKS 1322
+IP + V V N G+ S VY +D+ +A SLQ S
Sbjct: 768 -IIPLSPF----EVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFS 815
Score = 39.7 bits (91), Expect = 0.019
Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Query: 53 LVTRSSNIPAGDSVPEF-VEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKES 111
LV R+ + G+ P+ V P+ + A + GN P ISW+R G P+
Sbjct: 214 LVQRTDGV-MGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPL--P 270
Query: 112 AKIFYDSINKEHVLKLEPLTSDDSDNYKCIASN 144
K+ Y + +L++ +D Y+CIASN
Sbjct: 271 GKVKYS--KSQAILEIPNFQQEDEGFYECIASN 301
Score = 39.7 bits (91), Expect = 0.019
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 6/111 (5%)
Query: 51 FSLVTRSSNIPAGDSVPEFVEKP--QPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPI 108
+ ++ ++ + S P+F + P + G V + + ISWKR + +
Sbjct: 392 YQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTET-L 450
Query: 109 KESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTE 159
++S +IF + ++ LK+ +T D+ +Y CIA+N A T SL+V E
Sbjct: 451 RQSKRIF---LLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKE 498
Score = 34.3 bits (77), Expect = 0.82
Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 6/90 (6%)
Query: 1029 SGSPPPDVIWQKDGVPTKGRETITKSKNHSQFLINSTKRSDSGVYRILLQNE----FGEA 1084
SG P P W K+G E I + +I SDSGVY+ +N+ + A
Sbjct: 342 SGKPNPWYTWLKNGERLNPEERI--QIENGTLIITMLNVSDSGVYQCAAENKYQIIYANA 399
Query: 1085 RYDIHVRVADFPRPPTNLRLFEEVPNTVTL 1114
+ DF + P + F +V + +
Sbjct: 400 ELRVLASAPDFSKSPVKKKSFVQVGGDIVI 429
Score = 32.0 bits (71), Expect = 4.0
Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 12/91 (13%)
Query: 1000 AAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKN--- 1056
+AP F S +K V+ G + I + P + W++ G ET+ +SK
Sbjct: 406 SAPDFSKSP-VKKKSFVQVGGDIVIGCKPNAFPRAAISWKR------GTETLRQSKRIFL 458
Query: 1057 --HSQFLINSTKRSDSGVYRILLQNEFGEAR 1085
I + RSD+G Y + N+FG A+
Sbjct: 459 LEDGSLKIYNITRSDAGSYTCIATNQFGTAK 489
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,581,631
Number of Sequences: 37866
Number of extensions: 2606898
Number of successful extensions: 17120
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 228
Number of HSP's that attempted gapping in prelim test: 5856
Number of HSP's gapped (non-prelim): 4981
length of query: 1326
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1212
effective length of database: 13,930,794
effective search space: 16884122328
effective search space used: 16884122328
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.