BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] (1090 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] 2204 0.0 gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom... 951 0.0 gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ... 805 0.0 gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 296 5e-80 gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 296 5e-80 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 86 1e-16 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 86 1e-16 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 86 1e-16 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 86 1e-16 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 84 9e-16 gi|14249672 protein phosphatase 1, regulatory (inhibitor) subuni... 84 9e-16 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 83 1e-15 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 82 2e-15 gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 1... 82 3e-15 gi|163965366 nascent polypeptide-associated complex alpha subuni... 82 3e-15 gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 77 9e-14 gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 77 9e-14 gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 77 1e-13 gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit... 77 1e-13 gi|150170670 piccolo isoform 2 [Homo sapiens] 72 3e-12 gi|150378539 piccolo isoform 1 [Homo sapiens] 72 3e-12 gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 71 6e-12 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 69 2e-11 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 69 2e-11 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 69 2e-11 gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 69 3e-11 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 68 5e-11 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 67 9e-11 gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ... 67 9e-11 gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 67 1e-10 >gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] Length = 1090 Score = 2204 bits (5710), Expect = 0.0 Identities = 1090/1090 (100%), Positives = 1090/1090 (100%) Query: 1 MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDH 60 MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDH Sbjct: 1 MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDH 60 Query: 61 MMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGVG 120 MMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGVG Sbjct: 61 MMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGVG 120 Query: 121 NPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLK 180 NPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLK Sbjct: 121 NPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLK 180 Query: 181 ERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQ 240 ERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQ Sbjct: 181 ERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQ 240 Query: 241 QLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRN 300 QLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRN Sbjct: 241 QLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRN 300 Query: 301 MEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPV 360 MEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPV Sbjct: 301 MEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPV 360 Query: 361 LGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVK 420 LGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVK Sbjct: 361 LGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVK 420 Query: 421 QGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLE 480 QGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLE Sbjct: 421 QGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLE 480 Query: 481 RRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPA 540 RRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPA Sbjct: 481 RRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPA 540 Query: 541 GDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSA 600 GDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSA Sbjct: 541 GDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSA 600 Query: 601 LNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADG 660 LNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADG Sbjct: 601 LNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADG 660 Query: 661 STVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGP 720 STVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGP Sbjct: 661 STVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGP 720 Query: 721 NIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP 780 NIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP Sbjct: 721 NIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP 780 Query: 781 LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEA 840 LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEA Sbjct: 781 LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEA 840 Query: 841 PSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGE 900 PSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGE Sbjct: 841 PSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGE 900 Query: 901 FDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHC 960 FDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHC Sbjct: 901 FDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHC 960 Query: 961 AASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMN 1020 AASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMN Sbjct: 961 AASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMN 1020 Query: 1021 KGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYP 1080 KGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYP Sbjct: 1021 KGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYP 1080 Query: 1081 RIKPRQRTLA 1090 RIKPRQRTLA Sbjct: 1081 RIKPRQRTLA 1090 >gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo sapiens] Length = 1134 Score = 951 bits (2458), Expect = 0.0 Identities = 551/1154 (47%), Positives = 703/1154 (60%), Gaps = 90/1154 (7%) Query: 1 MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDH 60 MMPM LTV+LSNNEQ TEVP+TPET CRDVV+ CKEPGE CHLAEVW G+ERP+ + Sbjct: 7 MMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSERPVADNE 66 Query: 61 MMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGE-KRTENGV 119 M++ LQ++G +R EV+FFLRHE P + G R +Q+ +RN + VPGE +R ENGV Sbjct: 67 RMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPR-SQDPSLKRNGVKVPGEYRRKENGV 125 Query: 120 GNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKL 179 +PR++LTL+ELQ+MA+RQQQQIE QQQ+L KEQRL FLKQQ++RQQQ ++E EKL++L Sbjct: 126 NSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRL 185 Query: 180 KERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLS 239 KE E QE KLKK+RA++G V+ ++ NG L EIE+ + +FQ+K++E+ A+ +V++L+ Sbjct: 186 KEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELT 245 Query: 240 QQLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKR 299 +QLE LK G+++ A EL RLY+ELQ+RN+LNQEQN+KLQQQ+E LNKR Sbjct: 246 RQLEMLKNGRIDSHHDNQS-----AVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKR 300 Query: 300 NMEVAMMDKRISELRERLYGKKIQLNRVNGT------SSPQSPLSTSGRVAAVGPYIQVP 353 N EVA+MDKR++ELR+RL+ KK L + + PQ S RVAAVGPYIQ Sbjct: 301 NSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSS 360 Query: 354 SAGSFP----VLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVK--PVQVAG 407 + P +L P P S+ A+ G K P ++ ++S K + G Sbjct: 361 TMPRMPSRPELLVKPALPDG-SLVIQASEGPMKIQ---TLPNMRSGAASQTKGSKIHPVG 416 Query: 408 ADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG-------KQLPP 460 DW + + QG+ S +AL + + + + + PP Sbjct: 417 PDWSPSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPP 476 Query: 461 SYGTY-PSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQP------- 512 S+GT + + + + + +P P +P++ + LP G T QP Sbjct: 477 SFGTLRKNQSSEDILRDAQVANKNVAKVPPP---VPTKPKQINLPYFGQTNQPPSDIKPD 533 Query: 513 GSSQQIQ--------------QRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLA 558 GSSQQ+ Q+ V SP+ P G + SK E P A+RPF Sbjct: 534 GSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTP 593 Query: 559 DKGSRP-QSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKS------VKAVYGK 611 P + PQTV +SSIYSMY QQ P KN+Q A SAL K+ +VYGK Sbjct: 594 QPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGK 653 Query: 612 PVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLS 671 PV+ + H Q +P S EPE + ++ + E +PRPLS Sbjct: 654 PVIAAAQNQQQ-----HPENIYSNSQGKPGS----PEPETEPVSSVQENHENERIPRPLS 704 Query: 672 PTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFN 731 PTKL P + +P R QSDADLEALR+KL+NAPRPLKKRSSITEPEGP GPNIQKLLYQR Sbjct: 705 PTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTT 764 Query: 732 TLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDA 791 A P Y + + + V+ N + E+ + L E ++ Sbjct: 765 IAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNAST 824 Query: 792 NDNELPSPEP----EELICPQTTHQTAEPAEDNNNNVATV--------PTTEQIPSPVAE 839 ++++P+P P E P + E+ N V P P P E Sbjct: 825 ENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGE 884 Query: 840 APSPGEEQV---PPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDAS 896 PGE+ V PP S PP KRTNL+K SER HG+RV+FNPLALLLD+S Sbjct: 885 PEGPGEDSVSMRPPEITGQVSLPP----GKRTNLRKTGSERIAHGMRVKFNPLALLLDSS 940 Query: 897 LEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWT 956 LEGEFDLVQRIIYEV+DPS PNDEGIT LHNAVCAGH IVKFL+ FGVNVNAADSDGWT Sbjct: 941 LEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWT 1000 Query: 957 PLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKL 1016 PLHCAASCN+V +CK LVESGAA+FA T SD++TAADKCEEMEEGY QCSQFLYGVQEK+ Sbjct: 1001 PLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKM 1060 Query: 1017 GVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLL 1076 G+MNKGV YALWDYE QN DEL EGD +TI+ R+DE E EWWWARL D+EGYVP+NLL Sbjct: 1061 GIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLL 1120 Query: 1077 GLYPRIKPRQRTLA 1090 GLYPRIKPRQR+LA Sbjct: 1121 GLYPRIKPRQRSLA 1134 >gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo sapiens] Length = 1005 Score = 805 bits (2078), Expect = 0.0 Identities = 478/1030 (46%), Positives = 611/1030 (59%), Gaps = 88/1030 (8%) Query: 124 VELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERV 183 ++LTL+ELQ+MA+RQQQQIE QQQ+L KEQRL FLKQQ++RQQQ ++E EKL++LKE Sbjct: 1 MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA 60 Query: 184 EAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLE 243 E QE KLKK+RA++G V+ ++ NG L EIE+ + +FQ+K++E+ A+ +V++L++QLE Sbjct: 61 ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE 120 Query: 244 DLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEV 303 LK G+++ A EL RLY+ELQ+RN+LNQEQN+KLQQQ+E LNKRN EV Sbjct: 121 MLKNGRIDSHHDNQS-----AVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEV 175 Query: 304 AMMDKRISELRERLYGKKIQLNRVNGT------SSPQSPLSTSGRVAAVGPYIQVPSAGS 357 A+MDKR++ELR+RL+ KK L + + PQ S RVAAVGPYIQ + Sbjct: 176 AVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPR 235 Query: 358 FP----VLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVK--PVQVAGADWK 411 P +L P P S+ A+ G K P ++ ++S K + G DW Sbjct: 236 MPSRPELLVKPALPDG-SLVIQASEGPMKIQ---TLPNMRSGAASQTKGSKIHPVGPDWS 291 Query: 412 DPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG-------KQLPPSYGT 464 + + QG+ S +AL + + + + + PPS+GT Sbjct: 292 PSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGT 351 Query: 465 Y-PSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQP-------GSSQ 516 + + + + + +P P +P++ + LP G T QP GSSQ Sbjct: 352 LRKNQSSEDILRDAQVANKNVAKVPPP---VPTKPKQINLPYFGQTNQPPSDIKPDGSSQ 408 Query: 517 QIQ--------------QRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGS 562 Q+ Q+ V SP+ P G + SK E P A+RPF Sbjct: 409 QLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSK 468 Query: 563 RP-QSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKS------VKAVYGKPVLP 615 P + PQTV +SSIYSMY QQ P KN+Q A SAL K+ +VYGKPV+ Sbjct: 469 DTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIA 528 Query: 616 SGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKL 675 + H Q +P S EPE + ++ + E +PRPLSPTKL Sbjct: 529 AAQNQQQ-----HPENIYSNSQGKPGS----PEPETEPVSSVQENHENERIPRPLSPTKL 579 Query: 676 TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAG 735 P + +P R QSDADLEALR+KL+NAPRPLKKRSSITEPEGP GPNIQKLLYQR A Sbjct: 580 LPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAM 639 Query: 736 GMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNE 795 P Y + + + V+ N + E+ + L E ++ +++ Sbjct: 640 ETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSD 699 Query: 796 LPSPEP----EELICPQTTHQTAEPAEDNNNNVATV--------PTTEQIPSPVAEAPSP 843 +P+P P E P + E+ N V P P P E P Sbjct: 700 MPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGP 759 Query: 844 GEEQV---PPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGE 900 GE+ V PP S PP KRTNL+K SER HG+RV+FNPLALLLD+SLEGE Sbjct: 760 GEDSVSMRPPEITGQVSLPP----GKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGE 815 Query: 901 FDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHC 960 FDLVQRIIYEV+DPS PNDEGIT LHNAVCAGH IVKFL+ FGVNVNAADSDGWTPLHC Sbjct: 816 FDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHC 875 Query: 961 AASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMN 1020 AASCN+V +CK LVESGAA+FA T SD++TAADKCEEMEEGY QCSQFLYGVQEK+G+MN Sbjct: 876 AASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMN 935 Query: 1021 KGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYP 1080 KGV YALWDYE QN DEL EGD +TI+ R+DE E EWWWARL D+EGYVP+NLLGLYP Sbjct: 936 KGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYP 995 Query: 1081 RIKPRQRTLA 1090 RIKPRQR+LA Sbjct: 996 RIKPRQRSLA 1005 >gi|215820635 protein phosphatase 1, regulatory subunit 13 like [Homo sapiens] Length = 828 Score = 296 bits (759), Expect = 5e-80 Identities = 261/855 (30%), Positives = 374/855 (43%), Gaps = 118/855 (13%) Query: 296 LNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSA 355 ++ + ME+ ++ EL ++L + SP P +G + Y Sbjct: 25 MDLKQMELDTAAAKVDELTKQLESL--------WSDSPAPPGPQAGPPSRPPRYSSSSIP 76 Query: 356 GSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVK--PVQVAGADWKDP 413 F G P K + + ++ GRS+SA PTL S S K P + P Sbjct: 77 EPFGSRGSPRK--AATDGADTPFGRSESA-----PTLHPYSPLSPKGRPSSPRTPLYLQP 129 Query: 414 SVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG---KQLPPSYGTY----- 465 GS+ + T S +P F G + +G+ P P PG G +Q PP+ + Sbjct: 130 DAYGSLDRAT-SPRPRAFDGAGSS------LGRAPSPRPGPGPLRQQGPPTPFDFLGRAG 182 Query: 466 -PSPTPLGPGSTSSLERRKEGSLPRPSAGL----PSRQRPTLLPATGSTPQPGSSQQIQQ 520 P +PL G + R G PRP A S +LL + GS P Q Sbjct: 183 SPRGSPLAEGPQAFFPER--GPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL 240 Query: 521 RISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIY 580 + P + + A + KP + D +RP SP SS+ Sbjct: 241 TLRRRPPKAWNESDLDV--AYEKKPSQTASYE----RLDVFARPASPSLQLLPWRESSLD 294 Query: 581 SM------YLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTG 634 + L AT P+NY+ + ++ +S Y + + GS PS L S Sbjct: 295 GLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSL---GSAGPSGT--LPRSWQPV 349 Query: 635 TPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPL--SPTKLTPIVHSPLRYQSDADLE 692 + P PPS +P P S + L + SPL ++ Sbjct: 350 SRIPMPPSSP---QPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPP-- 404 Query: 693 ALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLL--------YQRFNTLAGGMEGTPFYQ 744 KL P+P + S +P+ P P Q Q + + G P + Sbjct: 405 ----KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPT-E 459 Query: 745 PSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEEL 804 P + G L V G+++E P A+P +P +PA +A +P E Sbjct: 460 LEPEPEIEGLLTPVLEA-----GDVDEGPVARPLSPTRLQPALPPEAQS--VPELEEVAR 512 Query: 805 ICPQTTHQTAEPAEDNNNNVATVPTT-----EQIPSPVAE---APSPGEEQV-------- 848 + + +P T +QI S + P PG + Sbjct: 513 VLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEG 572 Query: 849 ------PPAPLPPASHPPAT-----------STNKRTNLKKPNSERTGHGLRVRFNPLAL 891 PPAP PPA PP S R+ L+K S R R R NPL L Sbjct: 573 SEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKAR--RARLNPLVL 630 Query: 892 LLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAAD 951 LLDA+L GE ++VQ+ + E+ DPS+PN+EGIT LHNA+C ++ IV FL+ G NVN+ D Sbjct: 631 LLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPD 690 Query: 952 SDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYG 1011 S GWTPLHCAASCN +C LV+ GAAIFA+T+SD TA +KC+ EGY C+ +L Sbjct: 691 SHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCDPYREGYADCATYLAD 750 Query: 1012 VQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYV 1071 V++ +G+MN G YALWDY A+ DELSF EG+++T+LRR ET+WWWA L +EGYV Sbjct: 751 VEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYV 810 Query: 1072 PKNLLGLYPRIKPRQ 1086 P+N GL+PR+KP++ Sbjct: 811 PRNYFGLFPRVKPQR 825 >gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo sapiens] Length = 828 Score = 296 bits (759), Expect = 5e-80 Identities = 261/855 (30%), Positives = 374/855 (43%), Gaps = 118/855 (13%) Query: 296 LNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSA 355 ++ + ME+ ++ EL ++L + SP P +G + Y Sbjct: 25 MDLKQMELDTAAAKVDELTKQLESL--------WSDSPAPPGPQAGPPSRPPRYSSSSIP 76 Query: 356 GSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVK--PVQVAGADWKDP 413 F G P K + + ++ GRS+SA PTL S S K P + P Sbjct: 77 EPFGSRGSPRK--AATDGADTPFGRSESA-----PTLHPYSPLSPKGRPSSPRTPLYLQP 129 Query: 414 SVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG---KQLPPSYGTY----- 465 GS+ + T S +P F G + +G+ P P PG G +Q PP+ + Sbjct: 130 DAYGSLDRAT-SPRPRAFDGAGSS------LGRAPSPRPGPGPLRQQGPPTPFDFLGRAG 182 Query: 466 -PSPTPLGPGSTSSLERRKEGSLPRPSAGL----PSRQRPTLLPATGSTPQPGSSQQIQQ 520 P +PL G + R G PRP A S +LL + GS P Q Sbjct: 183 SPRGSPLAEGPQAFFPER--GPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL 240 Query: 521 RISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIY 580 + P + + A + KP + D +RP SP SS+ Sbjct: 241 TLRRRPPKAWNESDLDV--AYEKKPSQTASYE----RLDVFARPASPSLQLLPWRESSLD 294 Query: 581 SM------YLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTG 634 + L AT P+NY+ + ++ +S Y + + GS PS L S Sbjct: 295 GLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSL---GSAGPSGT--LPRSWQPV 349 Query: 635 TPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPL--SPTKLTPIVHSPLRYQSDADLE 692 + P PPS +P P S + L + SPL ++ Sbjct: 350 SRIPMPPSSP---QPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPP-- 404 Query: 693 ALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLL--------YQRFNTLAGGMEGTPFYQ 744 KL P+P + S +P+ P P Q Q + + G P + Sbjct: 405 ----KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPT-E 459 Query: 745 PSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEEL 804 P + G L V G+++E P A+P +P +PA +A +P E Sbjct: 460 LEPEPEIEGLLTPVLEA-----GDVDEGPVARPLSPTRLQPALPPEAQS--VPELEEVAR 512 Query: 805 ICPQTTHQTAEPAEDNNNNVATVPTT-----EQIPSPVAE---APSPGEEQV-------- 848 + + +P T +QI S + P PG + Sbjct: 513 VLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEG 572 Query: 849 ------PPAPLPPASHPPAT-----------STNKRTNLKKPNSERTGHGLRVRFNPLAL 891 PPAP PPA PP S R+ L+K S R R R NPL L Sbjct: 573 SEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKAR--RARLNPLVL 630 Query: 892 LLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAAD 951 LLDA+L GE ++VQ+ + E+ DPS+PN+EGIT LHNA+C ++ IV FL+ G NVN+ D Sbjct: 631 LLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPD 690 Query: 952 SDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYG 1011 S GWTPLHCAASCN +C LV+ GAAIFA+T+SD TA +KC+ EGY C+ +L Sbjct: 691 SHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCDPYREGYADCATYLAD 750 Query: 1012 VQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYV 1071 V++ +G+MN G YALWDY A+ DELSF EG+++T+LRR ET+WWWA L +EGYV Sbjct: 751 VEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYV 810 Query: 1072 PKNLLGLYPRIKPRQ 1086 P+N GL+PR+KP++ Sbjct: 811 PRNYFGLFPRVKPQR 825 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 86.3 bits (212), Expect = 1e-16 Identities = 126/564 (22%), Positives = 193/564 (34%), Gaps = 51/564 (9%) Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390 ++P+ P T+ + A P P+ P P +P + A + P Sbjct: 242 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 301 Query: 391 T-LKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449 + P + A K+P+ + + +P P + P + P Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361 Query: 450 --PIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTL---- 502 P P K+ P+ PSPT P P T++ P P+ ++ PT Sbjct: 362 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEP 418 Query: 503 LPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGS 562 P T P P + ++ P+PT P P P K P T K Sbjct: 419 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEP 474 Query: 563 RPQSPRK-GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSP 621 P +P++ P T + + T P+ P L + P P+ +T Sbjct: 475 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT------PEEPTPTTPE 528 Query: 622 SPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGS---TVESLPRPLSPTKL--- 675 P P + + TP+ P+ +T KEP P PA + T + P+ +PT L Sbjct: 529 EPAPTTPKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 586 Query: 676 ---TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT 732 TP +P E K ++ T P+ P P K + T Sbjct: 587 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA-PTTPK---EPAPT 642 Query: 733 LAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP------LPAEPA 786 G T +P+P+ ++ T + PA PT P P EPA Sbjct: 643 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-PTTPKETAPTTPKEPA 701 Query: 787 PSSDANDN----ELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPS 842 P++ E P P E+ P TT EP + + + P P+P A S Sbjct: 702 PTTPKKPAPTTPETPPPTTSEVSTPTTTK---EPTTIHKSPDESTPELSAEPTPKALENS 758 Query: 843 PGEEQVPPAPLPPASHPPATSTNK 866 P E VP P A+ P T+T K Sbjct: 759 PKEPGVPTTKTPAATKPEMTTTAK 782 Score = 60.1 bits (144), Expect = 1e-08 Identities = 96/453 (21%), Positives = 146/453 (32%), Gaps = 95/453 (20%) Query: 448 PPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507 PP + G L G + TP TS+ + K + P+ + P RP+L P + Sbjct: 82 PPVVDEAGSGL--DNGDFKVTTP----DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD 135 Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP-----------F 556 ++ + +S + + +V T + + T +I Sbjct: 136 TSKE--TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 193 Query: 557 LADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPS 616 LA + ++ KGP ++ TP +PA+ + + + P P Sbjct: 194 LAKPTPKAETTTKGPALTTP--------KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 245 Query: 617 GSTSPSPLPFLHGSLSTGTPQPQP-----PSESTEKEPEQDGPAAPADGSTVESLPRPLS 671 P P S T +P P P+ +T KEP PA +T + P Sbjct: 246 -----EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300 Query: 672 PTKLTPIVHSPLRYQSDADLEALRRK--LANAPRPLKKRSSITEPEGPGGPNIQKLLYQR 729 P TP +P + A P P K + T P+ P P K Sbjct: 301 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-PTAPK----- 354 Query: 730 FNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSS 789 +P+P+ P +P P EPAP++ Sbjct: 355 --------------KPAPTT------------------------PKEPAPTTPKEPAPTT 376 Query: 790 DANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVA---EAPSPGEE 846 + EP T EPA + PTT + PSP AP+ +E Sbjct: 377 TKEPSPTTPKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTTTKEPAPTTPKE 433 Query: 847 QVPPAPLPPA---SHPPATSTNKR---TNLKKP 873 P P PA PA +T K T KKP Sbjct: 434 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 466 Score = 60.1 bits (144), Expect = 1e-08 Identities = 105/512 (20%), Positives = 160/512 (31%), Gaps = 81/512 (15%) Query: 423 TVSSQPVPFSALGP----TEKPGIEIGKVPPPI------PGVGKQLPPSYGTYPSPTPLG 472 T +P P + P T+KP K P P P K+L P+ +PT Sbjct: 445 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 504 Query: 473 PGSTSSLERRKEGSLPRPSAGLPSRQRPTL----LPATGSTPQPGSSQQIQQRISVPPSP 528 + ++ E + P+ P PT P T P P + ++ P+P Sbjct: 505 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564 Query: 529 TYPPAGPPAFPAGDSK----------PELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSS 578 T P P P G + P+ P + P + + + P T ++ Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 624 Query: 579 IYSMYLQQATPPKNYQPA-----AHSALNKSVKAVYGKPVL----------PSGSTSPSP 623 + T PK P A + L + KP P+ +TS P Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684 Query: 624 LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPL 683 P T P+ P+ +T K+P P P T + P + + T I SP Sbjct: 685 APTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPP--TTSEVSTPTTTKEPTTIHKSPD 740 Query: 684 RYQSDADLEALRRKLANAPR----PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEG 739 + E + L N+P+ P K + T+PE + T + Sbjct: 741 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE--------MTTTAKDKTTERDLRT 792 Query: 740 TP---FYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEP------APSSD 790 TP P +++ T A Q T P AP Sbjct: 793 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 852 Query: 791 ANDNELPSPE----PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEE 846 + + E PEE TA+P + N+ AT P P +AP Sbjct: 853 TTKKTITTTEIMNKPEE---------TAKPKDRATNSKATTPK----PQKPTKAPKKPTS 899 Query: 847 QVPPAPLPPASHPPATSTNKRTNLKKPNSERT 878 P +P P T T ++ P T Sbjct: 900 TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 931 Score = 44.3 bits (103), Expect = 6e-04 Identities = 79/385 (20%), Positives = 133/385 (34%), Gaps = 53/385 (13%) Query: 331 SSPQSPLSTSGR-VAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNW 389 ++P+ P T+ + A P P+ P P KP +A + + D Sbjct: 557 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 616 Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSS---QPVPFSA-------LGPTEK 439 PT + ++ + P + A K+P+ + +GT + +P P + L PT Sbjct: 617 PTTPKGTAPTT-PKEPAPTTPKEPAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 673 Query: 440 PGIEIGKVPPPIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498 G P P K+ P+ P+PT P P T+ P P+ S Sbjct: 674 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-------ETPPPTTSEVSTP 726 Query: 499 RPTLLPAT------GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVA 552 T P T STP+ + + + P P P PA +KPE+ T Sbjct: 727 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAK 782 Query: 553 IRPFLADKGSRPQSPRKGPQ-----------------TVNSSSIYSMYLQQATPPKNYQP 595 + D + P++ P+ T ++ + S Q TP K Sbjct: 783 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 842 Query: 596 AAHSALNK---SVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQD 652 + K + K + ++ + P S +T TP+PQ P+++ +K Sbjct: 843 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT-TPKPQKPTKAPKKPTSTK 901 Query: 653 GPAAPADGSTVESLPRPLSPTKLTP 677 P ++ P P T P Sbjct: 902 KPKTMPRVRKPKTTPTPRKMTSTMP 926 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 86.3 bits (212), Expect = 1e-16 Identities = 126/564 (22%), Positives = 193/564 (34%), Gaps = 51/564 (9%) Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390 ++P+ P T+ + A P P+ P P +P + A + P Sbjct: 283 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 342 Query: 391 T-LKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449 + P + A K+P+ + + +P P + P + P Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 402 Query: 450 --PIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTL---- 502 P P K+ P+ PSPT P P T++ P P+ ++ PT Sbjct: 403 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEP 459 Query: 503 LPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGS 562 P T P P + ++ P+PT P P P K P T K Sbjct: 460 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEP 515 Query: 563 RPQSPRK-GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSP 621 P +P++ P T + + T P+ P L + P P+ +T Sbjct: 516 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT------PEEPTPTTPE 569 Query: 622 SPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGS---TVESLPRPLSPTKL--- 675 P P + + TP+ P+ +T KEP P PA + T + P+ +PT L Sbjct: 570 EPAPTTPKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 627 Query: 676 ---TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT 732 TP +P E K ++ T P+ P P K + T Sbjct: 628 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA-PTTPK---EPAPT 683 Query: 733 LAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP------LPAEPA 786 G T +P+P+ ++ T + PA PT P P EPA Sbjct: 684 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-PTTPKETAPTTPKEPA 742 Query: 787 PSSDANDN----ELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPS 842 P++ E P P E+ P TT EP + + + P P+P A S Sbjct: 743 PTTPKKPAPTTPETPPPTTSEVSTPTTTK---EPTTIHKSPDESTPELSAEPTPKALENS 799 Query: 843 PGEEQVPPAPLPPASHPPATSTNK 866 P E VP P A+ P T+T K Sbjct: 800 PKEPGVPTTKTPAATKPEMTTTAK 823 Score = 60.1 bits (144), Expect = 1e-08 Identities = 96/453 (21%), Positives = 146/453 (32%), Gaps = 95/453 (20%) Query: 448 PPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507 PP + G L G + TP TS+ + K + P+ + P RP+L P + Sbjct: 123 PPVVDEAGSGL--DNGDFKVTTP----DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD 176 Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP-----------F 556 ++ + +S + + +V T + + T +I Sbjct: 177 TSKE--TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 234 Query: 557 LADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPS 616 LA + ++ KGP ++ TP +PA+ + + + P P Sbjct: 235 LAKPTPKAETTTKGPALTTP--------KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 286 Query: 617 GSTSPSPLPFLHGSLSTGTPQPQP-----PSESTEKEPEQDGPAAPADGSTVESLPRPLS 671 P P S T +P P P+ +T KEP PA +T + P Sbjct: 287 -----EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341 Query: 672 PTKLTPIVHSPLRYQSDADLEALRRK--LANAPRPLKKRSSITEPEGPGGPNIQKLLYQR 729 P TP +P + A P P K + T P+ P P K Sbjct: 342 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-PTAPK----- 395 Query: 730 FNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSS 789 +P+P+ P +P P EPAP++ Sbjct: 396 --------------KPAPTT------------------------PKEPAPTTPKEPAPTT 417 Query: 790 DANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVA---EAPSPGEE 846 + EP T EPA + PTT + PSP AP+ +E Sbjct: 418 TKEPSPTTPKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTTTKEPAPTTPKE 474 Query: 847 QVPPAPLPPA---SHPPATSTNKR---TNLKKP 873 P P PA PA +T K T KKP Sbjct: 475 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 507 Score = 60.1 bits (144), Expect = 1e-08 Identities = 105/512 (20%), Positives = 160/512 (31%), Gaps = 81/512 (15%) Query: 423 TVSSQPVPFSALGP----TEKPGIEIGKVPPPI------PGVGKQLPPSYGTYPSPTPLG 472 T +P P + P T+KP K P P P K+L P+ +PT Sbjct: 486 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 545 Query: 473 PGSTSSLERRKEGSLPRPSAGLPSRQRPTL----LPATGSTPQPGSSQQIQQRISVPPSP 528 + ++ E + P+ P PT P T P P + ++ P+P Sbjct: 546 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605 Query: 529 TYPPAGPPAFPAGDSK----------PELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSS 578 T P P P G + P+ P + P + + + P T ++ Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 665 Query: 579 IYSMYLQQATPPKNYQPA-----AHSALNKSVKAVYGKPVL----------PSGSTSPSP 623 + T PK P A + L + KP P+ +TS P Sbjct: 666 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725 Query: 624 LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPL 683 P T P+ P+ +T K+P P P T + P + + T I SP Sbjct: 726 APTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPP--TTSEVSTPTTTKEPTTIHKSPD 781 Query: 684 RYQSDADLEALRRKLANAPR----PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEG 739 + E + L N+P+ P K + T+PE + T + Sbjct: 782 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE--------MTTTAKDKTTERDLRT 833 Query: 740 TP---FYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEP------APSSD 790 TP P +++ T A Q T P AP Sbjct: 834 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 893 Query: 791 ANDNELPSPE----PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEE 846 + + E PEE TA+P + N+ AT P P +AP Sbjct: 894 TTKKTITTTEIMNKPEE---------TAKPKDRATNSKATTPK----PQKPTKAPKKPTS 940 Query: 847 QVPPAPLPPASHPPATSTNKRTNLKKPNSERT 878 P +P P T T ++ P T Sbjct: 941 TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 972 Score = 44.3 bits (103), Expect = 6e-04 Identities = 79/385 (20%), Positives = 133/385 (34%), Gaps = 53/385 (13%) Query: 331 SSPQSPLSTSGR-VAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNW 389 ++P+ P T+ + A P P+ P P KP +A + + D Sbjct: 598 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 657 Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSS---QPVPFSA-------LGPTEK 439 PT + ++ + P + A K+P+ + +GT + +P P + L PT Sbjct: 658 PTTPKGTAPTT-PKEPAPTTPKEPAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 714 Query: 440 PGIEIGKVPPPIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498 G P P K+ P+ P+PT P P T+ P P+ S Sbjct: 715 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-------ETPPPTTSEVSTP 767 Query: 499 RPTLLPAT------GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVA 552 T P T STP+ + + + P P P PA +KPE+ T Sbjct: 768 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAK 823 Query: 553 IRPFLADKGSRPQSPRKGPQ-----------------TVNSSSIYSMYLQQATPPKNYQP 595 + D + P++ P+ T ++ + S Q TP K Sbjct: 824 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 883 Query: 596 AAHSALNK---SVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQD 652 + K + K + ++ + P S +T TP+PQ P+++ +K Sbjct: 884 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT-TPKPQKPTKAPKKPTSTK 942 Query: 653 GPAAPADGSTVESLPRPLSPTKLTP 677 P ++ P P T P Sbjct: 943 KPKTMPRVRKPKTTPTPRKMTSTMP 967 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 86.3 bits (212), Expect = 1e-16 Identities = 126/564 (22%), Positives = 193/564 (34%), Gaps = 51/564 (9%) Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390 ++P+ P T+ + A P P+ P P +P + A + P Sbjct: 335 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 394 Query: 391 T-LKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449 + P + A K+P+ + + +P P + P + P Sbjct: 395 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 454 Query: 450 --PIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTL---- 502 P P K+ P+ PSPT P P T++ P P+ ++ PT Sbjct: 455 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEP 511 Query: 503 LPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGS 562 P T P P + ++ P+PT P P P K P T K Sbjct: 512 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEP 567 Query: 563 RPQSPRK-GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSP 621 P +P++ P T + + T P+ P L + P P+ +T Sbjct: 568 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT------PEEPTPTTPE 621 Query: 622 SPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGS---TVESLPRPLSPTKL--- 675 P P + + TP+ P+ +T KEP P PA + T + P+ +PT L Sbjct: 622 EPAPTTPKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 679 Query: 676 ---TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT 732 TP +P E K ++ T P+ P P K + T Sbjct: 680 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA-PTTPK---EPAPT 735 Query: 733 LAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP------LPAEPA 786 G T +P+P+ ++ T + PA PT P P EPA Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-PTTPKETAPTTPKEPA 794 Query: 787 PSSDANDN----ELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPS 842 P++ E P P E+ P TT EP + + + P P+P A S Sbjct: 795 PTTPKKPAPTTPETPPPTTSEVSTPTTTK---EPTTIHKSPDESTPELSAEPTPKALENS 851 Query: 843 PGEEQVPPAPLPPASHPPATSTNK 866 P E VP P A+ P T+T K Sbjct: 852 PKEPGVPTTKTPAATKPEMTTTAK 875 Score = 60.1 bits (144), Expect = 1e-08 Identities = 96/453 (21%), Positives = 146/453 (32%), Gaps = 95/453 (20%) Query: 448 PPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507 PP + G L G + TP TS+ + K + P+ + P RP+L P + Sbjct: 175 PPVVDEAGSGL--DNGDFKVTTP----DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD 228 Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP-----------F 556 ++ + +S + + +V T + + T +I Sbjct: 229 TSKE--TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 286 Query: 557 LADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPS 616 LA + ++ KGP ++ TP +PA+ + + + P P Sbjct: 287 LAKPTPKAETTTKGPALTTP--------KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 338 Query: 617 GSTSPSPLPFLHGSLSTGTPQPQP-----PSESTEKEPEQDGPAAPADGSTVESLPRPLS 671 P P S T +P P P+ +T KEP PA +T + P Sbjct: 339 -----EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393 Query: 672 PTKLTPIVHSPLRYQSDADLEALRRK--LANAPRPLKKRSSITEPEGPGGPNIQKLLYQR 729 P TP +P + A P P K + T P+ P P K Sbjct: 394 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-PTAPK----- 447 Query: 730 FNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSS 789 +P+P+ P +P P EPAP++ Sbjct: 448 --------------KPAPTT------------------------PKEPAPTTPKEPAPTT 469 Query: 790 DANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVA---EAPSPGEE 846 + EP T EPA + PTT + PSP AP+ +E Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTTTKEPAPTTPKE 526 Query: 847 QVPPAPLPPA---SHPPATSTNKR---TNLKKP 873 P P PA PA +T K T KKP Sbjct: 527 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 559 Score = 60.1 bits (144), Expect = 1e-08 Identities = 105/512 (20%), Positives = 160/512 (31%), Gaps = 81/512 (15%) Query: 423 TVSSQPVPFSALGP----TEKPGIEIGKVPPPI------PGVGKQLPPSYGTYPSPTPLG 472 T +P P + P T+KP K P P P K+L P+ +PT Sbjct: 538 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 597 Query: 473 PGSTSSLERRKEGSLPRPSAGLPSRQRPTL----LPATGSTPQPGSSQQIQQRISVPPSP 528 + ++ E + P+ P PT P T P P + ++ P+P Sbjct: 598 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657 Query: 529 TYPPAGPPAFPAGDSK----------PELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSS 578 T P P P G + P+ P + P + + + P T ++ Sbjct: 658 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 717 Query: 579 IYSMYLQQATPPKNYQPA-----AHSALNKSVKAVYGKPVL----------PSGSTSPSP 623 + T PK P A + L + KP P+ +TS P Sbjct: 718 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777 Query: 624 LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPL 683 P T P+ P+ +T K+P P P T + P + + T I SP Sbjct: 778 APTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPP--TTSEVSTPTTTKEPTTIHKSPD 833 Query: 684 RYQSDADLEALRRKLANAPR----PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEG 739 + E + L N+P+ P K + T+PE + T + Sbjct: 834 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE--------MTTTAKDKTTERDLRT 885 Query: 740 TP---FYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEP------APSSD 790 TP P +++ T A Q T P AP Sbjct: 886 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 945 Query: 791 ANDNELPSPE----PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEE 846 + + E PEE TA+P + N+ AT P P +AP Sbjct: 946 TTKKTITTTEIMNKPEE---------TAKPKDRATNSKATTPK----PQKPTKAPKKPTS 992 Query: 847 QVPPAPLPPASHPPATSTNKRTNLKKPNSERT 878 P +P P T T ++ P T Sbjct: 993 TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1024 Score = 44.3 bits (103), Expect = 6e-04 Identities = 79/385 (20%), Positives = 133/385 (34%), Gaps = 53/385 (13%) Query: 331 SSPQSPLSTSGR-VAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNW 389 ++P+ P T+ + A P P+ P P KP +A + + D Sbjct: 650 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 709 Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSS---QPVPFSA-------LGPTEK 439 PT + ++ + P + A K+P+ + +GT + +P P + L PT Sbjct: 710 PTTPKGTAPTT-PKEPAPTTPKEPAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 766 Query: 440 PGIEIGKVPPPIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498 G P P K+ P+ P+PT P P T+ P P+ S Sbjct: 767 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-------ETPPPTTSEVSTP 819 Query: 499 RPTLLPAT------GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVA 552 T P T STP+ + + + P P P PA +KPE+ T Sbjct: 820 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAK 875 Query: 553 IRPFLADKGSRPQSPRKGPQ-----------------TVNSSSIYSMYLQQATPPKNYQP 595 + D + P++ P+ T ++ + S Q TP K Sbjct: 876 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 935 Query: 596 AAHSALNK---SVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQD 652 + K + K + ++ + P S +T TP+PQ P+++ +K Sbjct: 936 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT-TPKPQKPTKAPKKPTSTK 994 Query: 653 GPAAPADGSTVESLPRPLSPTKLTP 677 P ++ P P T P Sbjct: 995 KPKTMPRVRKPKTTPTPRKMTSTMP 1019 Score = 33.9 bits (76), Expect = 0.86 Identities = 53/271 (19%), Positives = 92/271 (33%), Gaps = 39/271 (14%) Query: 615 PSGSTSPSPLPFLHGSLSTGTPQPQPPSE-STEKEPEQDGPAAPADGSTVESLPRPLSPT 673 PS +P P ST P+PP++ T+K E + S + S + Sbjct: 73 PSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 132 Query: 674 KLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTL 733 + + ++ A L++KL + KK + +P P P + + Sbjct: 133 SSSSTIRKIKSSKNSAANRELQKKL--KVKDNKKNRTKKKPT-PKPPVVDE--------A 181 Query: 734 AGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDAND 793 G++ + DF T D N ++ A+P P P+ P S + + Sbjct: 182 GSGLD---------NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 232 Query: 794 NELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQI-----------------PSP 836 L + + +TT + + D + T+ I P+P Sbjct: 233 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 292 Query: 837 VAEAPSPGEE-QVPPAPLPPASHPPATSTNK 866 AE + G P P P PA++T K Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPK 323 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 86.3 bits (212), Expect = 1e-16 Identities = 126/564 (22%), Positives = 193/564 (34%), Gaps = 51/564 (9%) Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390 ++P+ P T+ + A P P+ P P +P + A + P Sbjct: 376 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 435 Query: 391 T-LKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449 + P + A K+P+ + + +P P + P + P Sbjct: 436 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 495 Query: 450 --PIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTL---- 502 P P K+ P+ PSPT P P T++ P P+ ++ PT Sbjct: 496 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEP 552 Query: 503 LPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGS 562 P T P P + ++ P+PT P P P K P T K Sbjct: 553 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEP 608 Query: 563 RPQSPRK-GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSP 621 P +P++ P T + + T P+ P L + P P+ +T Sbjct: 609 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT------PEEPTPTTPE 662 Query: 622 SPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGS---TVESLPRPLSPTKL--- 675 P P + + TP+ P+ +T KEP P PA + T + P+ +PT L Sbjct: 663 EPAPTTPKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 720 Query: 676 ---TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT 732 TP +P E K ++ T P+ P P K + T Sbjct: 721 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA-PTTPK---EPAPT 776 Query: 733 LAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP------LPAEPA 786 G T +P+P+ ++ T + PA PT P P EPA Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-PTTPKETAPTTPKEPA 835 Query: 787 PSSDANDN----ELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPS 842 P++ E P P E+ P TT EP + + + P P+P A S Sbjct: 836 PTTPKKPAPTTPETPPPTTSEVSTPTTTK---EPTTIHKSPDESTPELSAEPTPKALENS 892 Query: 843 PGEEQVPPAPLPPASHPPATSTNK 866 P E VP P A+ P T+T K Sbjct: 893 PKEPGVPTTKTPAATKPEMTTTAK 916 Score = 60.1 bits (144), Expect = 1e-08 Identities = 96/453 (21%), Positives = 146/453 (32%), Gaps = 95/453 (20%) Query: 448 PPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507 PP + G L G + TP TS+ + K + P+ + P RP+L P + Sbjct: 216 PPVVDEAGSGL--DNGDFKVTTP----DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD 269 Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP-----------F 556 ++ + +S + + +V T + + T +I Sbjct: 270 TSKE--TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 327 Query: 557 LADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPS 616 LA + ++ KGP ++ TP +PA+ + + + P P Sbjct: 328 LAKPTPKAETTTKGPALTTP--------KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 379 Query: 617 GSTSPSPLPFLHGSLSTGTPQPQP-----PSESTEKEPEQDGPAAPADGSTVESLPRPLS 671 P P S T +P P P+ +T KEP PA +T + P Sbjct: 380 -----EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434 Query: 672 PTKLTPIVHSPLRYQSDADLEALRRK--LANAPRPLKKRSSITEPEGPGGPNIQKLLYQR 729 P TP +P + A P P K + T P+ P P K Sbjct: 435 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-PTAPK----- 488 Query: 730 FNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSS 789 +P+P+ P +P P EPAP++ Sbjct: 489 --------------KPAPTT------------------------PKEPAPTTPKEPAPTT 510 Query: 790 DANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVA---EAPSPGEE 846 + EP T EPA + PTT + PSP AP+ +E Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTTTKEPAPTTPKE 567 Query: 847 QVPPAPLPPA---SHPPATSTNKR---TNLKKP 873 P P PA PA +T K T KKP Sbjct: 568 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 600 Score = 60.1 bits (144), Expect = 1e-08 Identities = 105/512 (20%), Positives = 160/512 (31%), Gaps = 81/512 (15%) Query: 423 TVSSQPVPFSALGP----TEKPGIEIGKVPPPI------PGVGKQLPPSYGTYPSPTPLG 472 T +P P + P T+KP K P P P K+L P+ +PT Sbjct: 579 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 638 Query: 473 PGSTSSLERRKEGSLPRPSAGLPSRQRPTL----LPATGSTPQPGSSQQIQQRISVPPSP 528 + ++ E + P+ P PT P T P P + ++ P+P Sbjct: 639 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698 Query: 529 TYPPAGPPAFPAGDSK----------PELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSS 578 T P P P G + P+ P + P + + + P T ++ Sbjct: 699 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 758 Query: 579 IYSMYLQQATPPKNYQPA-----AHSALNKSVKAVYGKPVL----------PSGSTSPSP 623 + T PK P A + L + KP P+ +TS P Sbjct: 759 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 818 Query: 624 LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPL 683 P T P+ P+ +T K+P P P T + P + + T I SP Sbjct: 819 APTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPP--TTSEVSTPTTTKEPTTIHKSPD 874 Query: 684 RYQSDADLEALRRKLANAPR----PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEG 739 + E + L N+P+ P K + T+PE + T + Sbjct: 875 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE--------MTTTAKDKTTERDLRT 926 Query: 740 TP---FYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEP------APSSD 790 TP P +++ T A Q T P AP Sbjct: 927 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 986 Query: 791 ANDNELPSPE----PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEE 846 + + E PEE TA+P + N+ AT P P +AP Sbjct: 987 TTKKTITTTEIMNKPEE---------TAKPKDRATNSKATTPK----PQKPTKAPKKPTS 1033 Query: 847 QVPPAPLPPASHPPATSTNKRTNLKKPNSERT 878 P +P P T T ++ P T Sbjct: 1034 TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1065 Score = 44.3 bits (103), Expect = 6e-04 Identities = 79/385 (20%), Positives = 133/385 (34%), Gaps = 53/385 (13%) Query: 331 SSPQSPLSTSGR-VAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNW 389 ++P+ P T+ + A P P+ P P KP +A + + D Sbjct: 691 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 750 Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSS---QPVPFSA-------LGPTEK 439 PT + ++ + P + A K+P+ + +GT + +P P + L PT Sbjct: 751 PTTPKGTAPTT-PKEPAPTTPKEPAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 807 Query: 440 PGIEIGKVPPPIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498 G P P K+ P+ P+PT P P T+ P P+ S Sbjct: 808 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-------ETPPPTTSEVSTP 860 Query: 499 RPTLLPAT------GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVA 552 T P T STP+ + + + P P P PA +KPE+ T Sbjct: 861 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAK 916 Query: 553 IRPFLADKGSRPQSPRKGPQ-----------------TVNSSSIYSMYLQQATPPKNYQP 595 + D + P++ P+ T ++ + S Q TP K Sbjct: 917 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 976 Query: 596 AAHSALNK---SVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQD 652 + K + K + ++ + P S +T TP+PQ P+++ +K Sbjct: 977 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT-TPKPQKPTKAPKKPTSTK 1035 Query: 653 GPAAPADGSTVESLPRPLSPTKLTP 677 P ++ P P T P Sbjct: 1036 KPKTMPRVRKPKTTPTPRKMTSTMP 1060 Score = 33.9 bits (76), Expect = 0.86 Identities = 53/271 (19%), Positives = 92/271 (33%), Gaps = 39/271 (14%) Query: 615 PSGSTSPSPLPFLHGSLSTGTPQPQPPSE-STEKEPEQDGPAAPADGSTVESLPRPLSPT 673 PS +P P ST P+PP++ T+K E + S + S + Sbjct: 114 PSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 173 Query: 674 KLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTL 733 + + ++ A L++KL + KK + +P P P + + Sbjct: 174 SSSSTIRKIKSSKNSAANRELQKKL--KVKDNKKNRTKKKPT-PKPPVVDE--------A 222 Query: 734 AGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDAND 793 G++ + DF T D N ++ A+P P P+ P S + + Sbjct: 223 GSGLD---------NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 273 Query: 794 NELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQI-----------------PSP 836 L + + +TT + + D + T+ I P+P Sbjct: 274 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 333 Query: 837 VAEAPSPGEE-QVPPAPLPPASHPPATSTNK 866 AE + G P P P PA++T K Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPK 364 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 83.6 bits (205), Expect = 9e-16 Identities = 154/591 (26%), Positives = 208/591 (35%), Gaps = 76/591 (12%) Query: 329 GTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIAS-------NAAHGRS 381 GT SP + VG PSA P P K S+S AS + A R Sbjct: 161 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK--SVSSASEHSTTEPSPAARRR 218 Query: 382 KSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVP--FSALGPTEK 439 SA G ++ SSS P+ PS G+ + SQP P AL P + Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARS--GPSARGTPRAPAHPSQPKPKGLQALRPPQ- 275 Query: 440 PGIEIGKVPPPIPGVGKQLPP-SYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498 V PP L P S +P+P P S S+ + +LP P A PS+ Sbjct: 276 -------VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ--TLPSPPATPPSQA 326 Query: 499 R-----PTL------LPATGSTPQPGSSQQIQQRISVPP--SPTYPPAGPPAFPAGDSKP 545 PTL LP+ +P Q +++PP +P PPA PP P P Sbjct: 327 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 386 Query: 546 ELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPA-AHSALNKS 604 + P +A+ A P P + P + +S S ATPP P+ A L Sbjct: 387 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS---PSATPPSQAPPSLAAPPLQVP 443 Query: 605 VKAVYGKPVLPSGSTSP-SPLPFLHGSLSTGTPQPQ-PPSESTEKEPEQDGPAAPADGST 662 P+ PS + P +P P L P PQ PP+ +T P Q P+ PA Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT--PPLQALPSPPA---- 497 Query: 663 VESLP--RPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGP 720 S P P SP+ P+ SPL L L P ++ P P P Sbjct: 498 --SFPGQAPFSPSASLPM--SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553 Query: 721 NIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELP--PAQPT 778 + TLA P SPS G D+ +++A EEL + P Sbjct: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG--PDLAGHSSSATSTPEELRGYDSGPE 611 Query: 779 APLPAEPAPSSDANDNELPSPEPEELI---CPQTTHQTAE------PAEDNNNNVATVPT 829 A P P D EL + P P + A P + + T Sbjct: 612 GGAAASPPP-----DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 666 Query: 830 TEQIPSPVAEAPSPGEEQVPPAPLPPAS-HPPATSTNKRTNLKKPNSERTG 879 + P + P+PG + P P P S A + + P R G Sbjct: 667 IYETEGPESATPAPG--ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 715 Score = 77.8 bits (190), Expect = 5e-14 Identities = 125/515 (24%), Positives = 193/515 (37%), Gaps = 83/515 (16%) Query: 398 SSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSA--LGPTEKPGIEIGKVPPPIPGVG 455 ++++ + AGA + P E + G + +P SA GPT PP G G Sbjct: 42 AALRVLGAAGAVGRKPLAE---RAGGIGGATIPESAPRAGPTRTSR-------PPASGRG 91 Query: 456 KQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSS 515 ++ PP+ T P P PG S R G L + + + + AT + + S Sbjct: 92 ERAPPAKNTSPGPVS-SPGRASGTTR--PGPLGQKGLRISAEETVARGKATEAPKRSALS 148 Query: 516 QQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGP-QTV 574 ++ S P T PA A ++ LP RP +RP+ P +GP ++V Sbjct: 149 AGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP-----RP---APSARPRPPTEGPRKSV 200 Query: 575 NSSSIYSMYLQQATPPKNYQPAAHSALN------------------KSVKAVYGKPVLPS 616 +S+S +S + +P +P+A L +S + G P P+ Sbjct: 201 SSASEHS--TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258 Query: 617 GSTSPSPLPFLHGSLSTGTPQPQPP-----------SESTEKEPEQDGPAAPADGSTVES 665 + P P G + PQ PP S S P P +P+ ++++ Sbjct: 259 HPSQPKP----KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314 Query: 666 LPRP--LSPTKLTPIVHSPL-----RYQSDADLEALRRKLANAPRPLKKRSSITEPEGPG 718 LP P P++ T + SP + L L AP L P P Sbjct: 315 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 374 Query: 719 GPNIQKLLY---QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGN-LEELPP 774 P + L Q N LA + PF P PS + + + + + PP Sbjct: 375 SPPLSPLATPSPQAPNALAVHLLQAPF-SPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433 Query: 775 AQPTAPLPAEPAP--SSDANDNELPSPE-PEELICPQTTHQTAEPAEDNNNNVATVPTTE 831 + PL P+P S + + P P+ P L P Q A+P +AT P + Sbjct: 434 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL--QLAKPPPQAPPALAT-PPLQ 490 Query: 832 QIPSPVA----EAPSPGEEQVPPAPL--PPASHPP 860 +PSP A +AP +P +PL PP PP Sbjct: 491 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 525 >gi|14249672 protein phosphatase 1, regulatory (inhibitor) subunit 16A [Homo sapiens] Length = 528 Score = 83.6 bits (205), Expect = 9e-16 Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 3/129 (2%) Query: 871 KKPNSERTGHGL--RVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNA 928 ++P E GL +V F P +LL+A+ + + V++ + P N++G+T LH Sbjct: 52 ERPRKEAASQGLLKQVLFPPSVVLLEAAARNDLEEVRQFLGSGVSPDLANEDGLTALHQC 111 Query: 929 VCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDI 988 +V+ LL+ G N+NA DS+ WTPLH AA+C +HL + L+ SGA + A +D Sbjct: 112 CIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVN-TDG 170 Query: 989 ETAADKCEE 997 D C++ Sbjct: 171 NMPYDLCDD 179 Score = 57.0 bits (136), Expect = 1e-07 Identities = 34/87 (39%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Query: 913 DPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQ 972 D P D G T LH A G LL+ +++A D DGW PLH AA V L + Sbjct: 224 DLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVEL 283 Query: 973 LVESGAAIFASTISDIETAADKCEEME 999 LV GA + A ++ D ET D C + E Sbjct: 284 LVAHGADLNAKSLMD-ETPLDVCGDEE 309 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 83.2 bits (204), Expect = 1e-15 Identities = 132/551 (23%), Positives = 192/551 (34%), Gaps = 75/551 (13%) Query: 330 TSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSL-SIASNAAHGRSKSANDGN 388 ++ P SP + P +Q + + L P+ L +++S A+H + Sbjct: 449 STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508 Query: 389 WPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPF-SALGPTEKPGIEIGKV 447 P L+ SS + +Q A P +E S P P +A P P +E Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLEN-----LPSLAPPPLQTASAPLTTPHLETPPC 563 Query: 448 PPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSA-GLPSRQRPTLLPAT 506 P P P Q PPS T P P P S ++ + +L P GLPS P L P Sbjct: 564 PAPCP---LQAPPSPLTTPPPET--PSSIATPPPQAPPALASPPLQGLPS---PPLSPL- 614 Query: 507 GSTPQPGSSQQIQQRISVPP--SPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRP 564 +TP P Q +++PP +P PPA PP P P+ P +A+ A P Sbjct: 615 -ATPPP----QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669 Query: 565 QSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPL 624 P + P + +S S ATPP P+ A V PS SP Sbjct: 670 SPPVQAPFSPPASPPVS---PSATPPSQAPPSL---------AAPPLQVPPSPPASPPMS 717 Query: 625 PFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLR 684 P +T PQ PP + + PA+P P+SP+ P PL Sbjct: 718 P-----SATPPPQAPPPLAAPPLQVPPSPPASP-----------PMSPSATPPPRVPPL- 760 Query: 685 YQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQ 744 L A ++ +P S + +P P + Q + G + Sbjct: 761 ------LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814 Query: 745 PSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPL------PAEPAPSSDANDNEL-- 796 PS S L ++PP+ P +P P P P + + L Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874 Query: 797 ---PSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPL 853 P P P P +T + A +++ +T S P G PP Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS----GPEGGAAASPPPDA 930 Query: 854 P-PASHPPATS 863 A HP A S Sbjct: 931 ELAACHPAAWS 941 Score = 74.7 bits (182), Expect = 4e-13 Identities = 119/493 (24%), Positives = 176/493 (35%), Gaps = 41/493 (8%) Query: 428 PVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSL 487 P+P + P+ P ++ PP P Q PPS T P P P + + SL Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPP--SQAPPSMTTPPMQAP--PSLQTIPPIQVPHSL 395 Query: 488 PRPSAGLPSRQRPTLLPATGSTPQPGSS--QQIQQRISVPPSPTYPPAGPPAFPAG---D 542 PS P P L + +T GS Q +++ P T P+ PA D Sbjct: 396 TSPSLQAPPS--PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453 Query: 543 SKP-ELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQAT---------PPKN 592 S P + PL++ P L S SP P T++ S + PP Sbjct: 454 SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE 513 Query: 593 YQPA-AHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQP-PSESTEKEPE 650 Q + A +L ++ P+ S +P PL L+T + P P+ + P Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573 Query: 651 QDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSS 710 P + + + P P +P L PL+ L L AP L Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALAS---PPLQGLPSPPLSPLATPPPQAPPXLALPPL 630 Query: 711 ITEPEGPGGPNIQKLLY---QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANG 767 P P P + L Q N LA + PF P PS + + + + Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF-SPPPSPPVQAPFSPPASPPVSPSA 689 Query: 768 NL-EELPPAQPTAPLPAEPAP--SSDANDNELPSPE-PEELICPQTTHQTAEPAEDNNNN 823 + PP+ PL P+P S + + P P+ P L P + PA + Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP 749 Query: 824 VATVP--TTEQIPSPVAEAPSPGEEQVPPAPL--PPASHPPATSTNKRTNLKKPNSERTG 879 AT P + +P + P +P +PL PP PPA +T L P + G Sbjct: 750 SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG 809 Query: 880 HGLRVRFNPLALL 892 + F+P A L Sbjct: 810 ---QAPFSPSASL 819 Score = 68.6 bits (166), Expect = 3e-11 Identities = 125/490 (25%), Positives = 185/490 (37%), Gaps = 83/490 (16%) Query: 398 SSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSA--LGPTEKPGIEIGKVP--PPIPG 453 ++++ + AGA + P E + G + +P SA GPT G PP G Sbjct: 42 AALRVLGAAGAVGRKPLAE---RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASG 98 Query: 454 VGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPG 513 G++ PP+ T P P PG S R G L + + + + AT + + Sbjct: 99 RGERAPPAKNTSPGPVS-SPGRASGTTR--PGPLGQKGLRISAEETVARGKATEAPKRSA 155 Query: 514 SSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGP-Q 572 S ++ S P T PA A ++ LP RP +RP+ P +GP + Sbjct: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP-----RP---APSARPRPPTEGPRK 207 Query: 573 TVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPL--PFLHGS 630 +V+S+S +S + +P +P+A L +P S S+S +PL P G Sbjct: 208 SVSSASEHS--TTEPSPAARRRPSAGGGLQ--------RPASRSLSSSATPLSSPARSGP 257 Query: 631 LSTGTP-------QPQPPSESTEKEPEQDGP---AAPADG---STVESLPRPLSPTKLTP 677 + GTP QP+P + P+ P AAPA G S+ + P P S TK P Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP-SGTKARP 316 Query: 678 IVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGM 737 + D L L +P PL + P P++Q L Sbjct: 317 VP------PPDNAATPLPATLPPSP-PLATPLPLAPPSPSAPPSLQTL---------PSP 360 Query: 738 EGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELP 797 TP Q PS + A +L+ +PP Q P S + + Sbjct: 361 PATPPSQAPPS---------MTTPPMQAPPSLQTIPPIQ---------VPHSLTSPSLQA 402 Query: 798 SPEPEELICPQTTHQTAEPAEDNNNNVATV---PTTEQIPSPVAEAPSPGEEQVPPAPLP 854 P P L Q T P ++ T+ T + SP A +P + APL Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462 Query: 855 -PASHPPATS 863 PAS P TS Sbjct: 463 LPASPPLQTS 472 Score = 31.6 bits (70), Expect = 4.3 Identities = 47/191 (24%), Positives = 68/191 (35%), Gaps = 24/191 (12%) Query: 331 SSPQSPLSTSGRVAA---VGPYIQVP-SAGSFPVLGDPIKPQSLSIASNAAHGRSKSA-N 385 S P SPL+T A P +QVP S + P L P +P + ++ + R A Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 877 Query: 386 DGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVK------QGTVSSQPVPFSALGPTEK 439 G P ++ SS++ +AG S ++ +G ++ P P + L Sbjct: 878 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 937 Query: 440 PGIEIGKVPP----PIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLP 495 G PP PG PP+ GPGS L E P + P Sbjct: 938 AAWSRGPAPPLAFRGAPGAPLPWPPA---------TGPGSADGLCTIYETEGPESATPAP 988 Query: 496 SRQRPTLLPAT 506 P P T Sbjct: 989 GALDPGPSPGT 999 Score = 31.2 bits (69), Expect = 5.6 Identities = 32/147 (21%), Positives = 48/147 (32%), Gaps = 12/147 (8%) Query: 734 AGGMEGTPFYQPSPSQD---FMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSD 790 AGG+ G + +P GT + A+G E PPA+ T+P P + Sbjct: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121 Query: 791 ANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP------- 843 P + I + T + E + + P PSP Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181 Query: 844 --GEEQVPPAPLPPASHPPATSTNKRT 868 G E P P P A P T +++ Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKS 208 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 82.4 bits (202), Expect = 2e-15 Identities = 156/616 (25%), Positives = 211/616 (34%), Gaps = 96/616 (15%) Query: 329 GTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIAS-------NAAHGRS 381 GT SP + VG PSA P P K S+S AS + A R Sbjct: 170 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK--SVSSASEHSTTEPSPAARRR 227 Query: 382 KSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFS--------- 432 SA G ++ SSS P+ PS G+ + SQP P Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARS--GPSARGTPRAPAHPSQPKPKGLQALRPPQV 285 Query: 433 ---------ALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYP----------SPTPLGP 473 ALGP + P P + Q PP+ P +P PL P Sbjct: 286 TPPRKDAAPALGPLSSSPLA---TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342 Query: 474 GSTSSLERRKEGSLPRPSAGLPSRQR-----PTL------LPATGSTPQPGSSQQIQQRI 522 S S+ + +LP P A PS+ PTL LP+ +P Q + Sbjct: 343 PSPSAPPSLQ--TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400 Query: 523 SVPP--SPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIY 580 ++PP +P PPA PP P P+ P +A+ A P P + P + +S Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460 Query: 581 SMYLQQATPPKNYQPA-AHSALNKSVKAVYGKPVLPSGSTSP-SPLPFLHGSLSTGTPQP 638 S ATPP P+ A L P+ PS + P +P P L P P Sbjct: 461 S---PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517 Query: 639 Q-PPSESTEKEPEQDGPAAPADGSTVESLP--RPLSPTKLTPIVHSPLRYQSDADLEALR 695 Q PP+ +T P Q P+ PA S P P SP+ P+ SPL L Sbjct: 518 QAPPALAT--PPLQALPSPPA------SFPGQAPFSPSASLPM--SPLATPPPQAPPVLA 567 Query: 696 RKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTL 755 L P ++ P P P + TLA P SPS G Sbjct: 568 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG-- 625 Query: 756 ADVDNGNTNANGNLEELP--PAQPTAPLPAEPAPSSDANDNELPSPEPEELI---CPQTT 810 D+ +++A EEL + P A P P D EL + P P Sbjct: 626 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP-----DAELAACHPAAWSRGPAPPLA 680 Query: 811 HQTAE------PAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPAS-HPPATS 863 + A P + + T + P + P+PG + P P P S A Sbjct: 681 FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG--ALDPGPSPGTSGGKAAAG 738 Query: 864 TNKRTNLKKPNSERTG 879 + + P R G Sbjct: 739 AGAGASSRSPKQARLG 754 Score = 79.3 bits (194), Expect = 2e-14 Identities = 126/495 (25%), Positives = 188/495 (37%), Gaps = 83/495 (16%) Query: 398 SSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSA--LGPTEKPGIEIGKVP--PPIPG 453 ++++ + AGA + P E + G + +P SA GPT G PP G Sbjct: 42 AALRVLGAAGAVGRKPLAE---RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASG 98 Query: 454 VGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPG 513 G++ PP+ T P P PG S R G L + + + + AT + + Sbjct: 99 RGERAPPAKNTSPGPVS-SPGRASGTTR--PGPLGQKGLRISAEETVARGKATEAPKRSA 155 Query: 514 SSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGP-Q 572 S ++ S P T PA A ++ LP RP +RP+ P +GP + Sbjct: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP-----RP---APSARPRPPTEGPRK 207 Query: 573 TVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPL--PFLHGS 630 +V+S+S +S + +P +P+A L +P S S+S +PL P G Sbjct: 208 SVSSASEHS--TTEPSPAARRRPSAGGGLQ--------RPASRSLSSSATPLSSPARSGP 257 Query: 631 LSTGTP-------QPQPPSESTEKEPEQDGP---AAPADGSTVESLPRPLSPTKL-TPIV 679 + GTP QP+P + P+ P AAPA G PLS + L TP Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG--------PLSSSPLATPSP 309 Query: 680 HSPLRYQSDADLEA------LRRKLAN-----APRPLKKRSSITEPEGPGGPNIQKLLYQ 728 + L+ Q+ L A L +LA P P S T P P P Q Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369 Query: 729 RFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPS 788 TL + T + PSP + T + PPA PL A P+P Sbjct: 370 GSPTL----QATHSFLPSPPLSPLATPP-------------PQAPPALALPPLQAPPSPP 412 Query: 789 SDANDNELPSPEPEELICPQ--TTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEE 846 + + L +P P+ P H P + P + PV+ + +P + Sbjct: 413 ASPPLSPLATPSPQ---APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 469 Query: 847 QVPPAPLPPASHPPA 861 P PP PP+ Sbjct: 470 APPSLAAPPLQVPPS 484 Score = 31.2 bits (69), Expect = 5.6 Identities = 32/147 (21%), Positives = 48/147 (32%), Gaps = 12/147 (8%) Query: 734 AGGMEGTPFYQPSPSQD---FMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSD 790 AGG+ G + +P GT + A+G E PPA+ T+P P + Sbjct: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121 Query: 791 ANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP------- 843 P + I + T + E + + P PSP Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181 Query: 844 --GEEQVPPAPLPPASHPPATSTNKRT 868 G E P P P A P T +++ Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKS 208 >gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 16B [Homo sapiens] Length = 567 Score = 82.0 bits (201), Expect = 3e-15 Identities = 46/119 (38%), Positives = 63/119 (52%), Gaps = 1/119 (0%) Query: 879 GHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVK 938 G +V F LL+ASL + + V+ + P N++G+T LH IVK Sbjct: 59 GRRKKVSFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVK 118 Query: 939 FLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEE 997 LL G NVNA D++ WTPLH AA+C ++L K LV+ GA + A SD D CE+ Sbjct: 119 LLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVN-SDGNMPYDLCED 176 Score = 60.1 bits (144), Expect = 1e-08 Identities = 34/80 (42%), Positives = 43/80 (53%), Gaps = 1/80 (1%) Query: 920 EGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAA 979 +G T LH A G+ + LLD GV V+ D DGW PLH AA + + + LV GA+ Sbjct: 228 QGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGAS 287 Query: 980 IFASTISDIETAADKCEEME 999 + A T D E D CEE E Sbjct: 288 LSARTSMD-EMPIDLCEEEE 306 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 82.0 bits (201), Expect = 3e-15 Identities = 138/540 (25%), Positives = 190/540 (35%), Gaps = 94/540 (17%) Query: 413 PSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPP--IPGVGKQLPPS-YGTYPSPT 469 PS +G + P +A P+ K G+ PPP P PPS G +P+ Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGLA---TPPPKGAPTTPAATPPSPKGGLATPS 1190 Query: 470 PLG-PGSTSSLERRKEGSLPRPSA-GLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPS 527 P G P + ++ +G L PS G P+ T G P + PPS Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250 Query: 528 P-----TYPPAGPPAFPAGDSKPELPLTVAIRPFL-----------ADKGSRPQSPRKGP 571 P T PP G P PA + P L +A P + KG SP KG Sbjct: 1251 PKGGPATPPPKGAPTPPAA-TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309 Query: 572 QTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSL 631 T +++ S TPP P + S K G P LP+ + S P S Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK---GTPTLPATTPSSKGGPTTPSSK 1366 Query: 632 STGTPQPQPPSES-----TEKEPEQDGPAAPAD-GSTVESLPRPLSPTKL--TPIVHSPL 683 TP PS T P++ GPA P+ G PLSP K TP+ Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKR-GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGA 1425 Query: 684 RYQSDADLEALRRKLANAPRPLKKRSSITEPEG-PGGPNIQKLLYQRFNTLAGGMEGTPF 742 S DL A P LKK + + P+G P P+ + TL +P Sbjct: 1426 ATPSKGDLTPP----AVTPVSLKKAPATSAPKGGPATPSSKG-----DPTLPAVTPPSPK 1476 Query: 743 YQPSPSQDFMGTLADVDNGNTNANG----------NLEELP--------PAQPTAPLPAE 784 P+P Q + G + +E+P P PTA L ++ Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK 1536 Query: 785 PAPSSDANDNEL-------PSPEPEELI-CPQTTHQTAEPAEDNNNNVATVPTTEQIPSP 836 P++ A L PSP+ I P+ T E ++ T T + PSP Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596 Query: 837 -------VAEAPSPGEEQVPPAPLPP--------------ASHPPATSTNKRTNLKKPNS 875 +PSP E PPA PP + PP T ++ + + P S Sbjct: 1597 KELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656 Score = 80.1 bits (196), Expect = 1e-14 Identities = 138/562 (24%), Positives = 182/562 (32%), Gaps = 84/562 (14%) Query: 331 SSPQS-PLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNW 389 SSP+ P SG A S G+ L D P +S++ +K + G Sbjct: 765 SSPKECPTEDSGASATAS------SKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGP- 817 Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449 T N SS V PV+ + S +GS + P P S G + Sbjct: 818 DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT------ 871 Query: 450 PIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGST 509 P+ G LPP +PTP S +L KEG P+ ++ L T S+ Sbjct: 872 PLSPKGVTLPPK----ETPTP----SVVNLPFPKEGP------ATPAPKQAPALSMTSSS 917 Query: 510 PQPGSSQQIQQRISVPPSPTY---PPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQS 566 P+ + + I PSP PPA P P G P P + P S Sbjct: 918 PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP-----AATPPS 972 Query: 567 PRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSA-LNKSVKAVYGKPVL--PSGSTSPSP 623 P+ GP T + TPP P+ S K P + PS SP+ Sbjct: 973 PKGGPATPSPKG-------APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025 Query: 624 LPFLHGSLSTGTPQPQPPSESTEKEPEQDG----PAA----PADGSTVESLPRPLSPTKL 675 PF G+ + P P S P G PAA P G SL +P Sbjct: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085 Query: 676 TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQR-----F 730 TP P A + A P + + P G P Sbjct: 1086 TP----PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141 Query: 731 NTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNA-------NGNLEELPPAQPTAPLPA 783 G TP P + + T T A G P PT P Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201 Query: 784 EPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP 843 P+P L +P P+ TT P+ +AT +P A PSP Sbjct: 1202 PPSPKGG-----LATPSPKG---APTTPAATPPSP--KGGLATPSPKGAPTTPAATPPSP 1251 Query: 844 -GEEQVPP---APLPPASHPPA 861 G PP AP PPA+ PP+ Sbjct: 1252 KGGPATPPPKGAPTPPAATPPS 1273 Score = 79.0 bits (193), Expect = 2e-14 Identities = 126/502 (25%), Positives = 181/502 (36%), Gaps = 79/502 (15%) Query: 413 PSVEGSVKQGTVSSQPVPFSALGPTEK-----PGIEIGKVPP----PIPGVGKQLPPSYG 463 PS +G ++ P P +A P+ K P + +PP P P G PP G Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124 Query: 464 --TYPSPTPLGPGSTSSLERRK------EGSLPRPSAGL---PSRQRPTLLPATGSTPQP 512 T P+ TP P + K + P P GL P + PT AT +P+ Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184 Query: 513 GSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPE---LPLTVAIRPFLADKGSRPQSPRK 569 G + S +PT P A PP+ G + P P T A P G SP K Sbjct: 1185 GLATP-----SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-K 1238 Query: 570 GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVL-----PSGSTSPSPL 624 G T +++ S ATPP P +A S+K P P+ T PSP Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP- 1297 Query: 625 PFLHGSLSTGTPQPQP-PSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPL 683 G +T P+ P P +T P+ P G+ P SP K TP + Sbjct: 1298 ---KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP-KGTPTLP--- 1350 Query: 684 RYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFY 743 A P ++ + EGP P + GG TP Sbjct: 1351 ---------------ATTPSSKGGPTTPSSKEGPTPPAATP-------SHKGGPAMTP-- 1386 Query: 744 QPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEE 803 PSP + G G+ + + P P P+ E A + D P+ P Sbjct: 1387 -PSPKR---GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442 Query: 804 LI-CPQTTHQTAEPAEDNNNN-----VATVPTTEQIPSP--VAEAPSPGEEQVPPAPLPP 855 L P T+ PA ++ T P+ ++ P+P VA + SP + PAP+ Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502 Query: 856 ASHPPATSTNKRTNLKKPNSER 877 + P ++ + P+S R Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRR 1524 Score = 64.7 bits (156), Expect = 5e-10 Identities = 142/596 (23%), Positives = 202/596 (33%), Gaps = 103/596 (17%) Query: 337 LSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNS 396 L+T A P + P + P G P + AA S + G P + Sbjct: 1278 LATPPHKGAPNPAVVTPPS---PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334 Query: 397 SSSVKPVQVAGADW---KDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPG 453 +V P G PS +G + P P +A P+ K G + PP P Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT-PSHKGG---PAMTPPSPK 1390 Query: 454 VGKQLPPSYG--TYPSPTPLGPGSTSSLERRKEGSLPRPSAG--LPSRQRPTLL---PAT 506 G +P G T P+ PL P + +EG+ PS G P P L PAT Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT-PSKGDLTPPAVTPVSLKKAPAT 1449 Query: 507 ----GSTPQPGSSQQIQQRISVPPSPTYPPAGP-----------PAFPAGDSKPELPLTV 551 G P S PPSP PPA PA PA P LP + Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509 Query: 552 AIRPFLADKGSRPQSPRKGPQTVNSS----SIYSMYLQQATP----PKN--YQPAAHSAL 601 P SP++ P T +S + + L + TP PK PA Sbjct: 1510 ------------PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557 Query: 602 NKSVKAV---YGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQ----PPSESTEKEPE---- 650 K A+ P PS + SP P + S G P P+ PP+ ++ E Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSP-PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616 Query: 651 --------QDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAP 702 + GPA PA T S P S K +P + + + A + + L Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK 1676 Query: 703 RPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFY-QPSPSQDFMGTLADV--- 758 P + + P P I + T P PS G L+ V Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA 1736 Query: 759 ------DNGNTNANGNLEELPPAQPTAPLPAEPAP--SSDANDNELPSPEPEELICPQTT 810 + + A G P P AP ++ + ++ A + LP PE + + Sbjct: 1737 PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP 1796 Query: 811 HQTAEPAEDNNNNVATVPTTEQI----PSPVAEAPS----PGEEQ-----VPPAPL 853 + A + V T+P +Q P V E+PS P +E +PP P+ Sbjct: 1797 PVSLPLAP---SPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPI 1849 Score = 60.1 bits (144), Expect = 1e-08 Identities = 92/367 (25%), Positives = 133/367 (36%), Gaps = 78/367 (21%) Query: 332 SPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPT 391 S ++P + + + A + P + VPS P + P + + P+ Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT-------------------PS 1575 Query: 392 LKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQP--VPFSALGPTEKPGIEIGKVPP 449 K+ SS P+V S +G S + +P + P+ K V P Sbjct: 1576 SKEASSP--------------PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621 Query: 450 PIPGVGKQLPPSYGTYPSP--TPLG----PGSTSSLERRKEGSLPRPSAGLPSRQRPTLL 503 P P G P GT SP TP P S +S+ + ++P+ S GLP+++ PT L Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681 Query: 504 PATGSTPQPGSSQQIQQRISVPP-----SPTYPPAGPPAFPAGDSKPELPLTVAIRPFL- 557 P P S+ I P S T PP P SK L TVA P L Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS-TVAPAPLLP 1740 Query: 558 -----------ADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVK 606 D P+ P P++ S+ + + ++ P + SV Sbjct: 1741 VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPE---------SASVS 1791 Query: 607 AVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESL 666 A PV S +PSP+P L P ES K P APAD + L Sbjct: 1792 AAPSPPV--SLPLAPSPVPTLPPKQQFLPSSPGLVLESPSK------PLAPADEDELLPL 1843 Query: 667 --PRPLS 671 P P+S Sbjct: 1844 IPPEPIS 1850 Score = 50.1 bits (118), Expect = 1e-05 Identities = 137/582 (23%), Positives = 206/582 (35%), Gaps = 141/582 (24%) Query: 332 SPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPT 391 SPQ+P G ++ GP + P+A S P+ S A + + Sbjct: 257 SPQNP----GSLSLKGP-VSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAP 311 Query: 392 LKQNSSSSVKPV-QVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPP 450 L Q+S SV+ + Q + DP+V+ T+S A P+++ V PP Sbjct: 312 LHQSSFGSVQLLGQTGPSALSDPTVK------TISVDHSSTGASYPSQR------SVIPP 359 Query: 451 IPGVGKQLPPSYGTYPSPTPL---GPGSTSSLERRKEGSL---------PRPSAGLPSRQ 498 +P + +P + +P P GP + SS+ GSL P S L S Sbjct: 360 LPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSP 419 Query: 499 RPTL---------LPATGSTPQPGSSQQIQQRISVPPSPTYPPA---GPP--AFPAGDSK 544 T + + G+TP ++ I+ P+ T+ A PP + P + + Sbjct: 420 NATYHYPLVAQMPVSSVGTTPLVVTNPCT---IAAAPTTTFEVATCVSPPMSSGPISNIE 476 Query: 545 PELPLTVAIRPFLADKGSR--------PQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPA 596 P P + + P + S P SP P + ++ S L + K+ Q Sbjct: 477 PTSPAALVMAPVAPKEPSTQVATTLRIPVSPPL-PDPEDLKNLPSSVLVKFPTQKDLQTV 535 Query: 597 AHSALNKSVKAVYGKPVLPS--GSTS---PSPLPFLHGSLSTGTPQPQPPSESTEKEPEQ 651 S + G P P+ G T+ P+ LP + + P+ P +ST PE Sbjct: 536 PAS--------LEGAPFSPAQAGLTTKKDPTVLPLVQAA-----PKNSPSFQSTSSSPEI 582 Query: 652 DGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLA-NAPRPLKKRSS 710 P +P +SL PL K + SPL S A + ++ PL K S Sbjct: 583 --PLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSL 640 Query: 711 IT--------EPEGPGG--PNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDN 760 IT E P G P K GT Y + S GT++ Sbjct: 641 ITPTVAAFPLESADPAGVAPTTAK--------------GTSTYTTTASPFLEGTVSLAPK 686 Query: 761 GNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDN 820 + G L LP PTA ++N +P P+ P Sbjct: 687 NHPVKEGTLTTLPLV-PTA------------SENCPVAPSPQNTCAP------------- 720 Query: 821 NNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPAT 862 +AT+ +IP V PSP LPPA PP T Sbjct: 721 ---LATLVLAPEIPKSV---PSPS--------LPPAGTPPGT 748 Score = 37.0 bits (84), Expect = 0.10 Identities = 49/216 (22%), Positives = 78/216 (36%), Gaps = 48/216 (22%) Query: 473 PGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPP 532 PG + E LP+P A + L T + QPG PT PP Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPG--------------PTLPP 47 Query: 533 AGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATP--- 589 P + + PL+ A SP P T+ S+ + + Q ++ Sbjct: 48 ------PCSPAPQQCPLSAA----------NQASPFPSPSTIASTPLEVPFPQSSSGTAL 91 Query: 590 PKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPL--PFLHGSLSTGTP------QPQPP 641 P P A + L + G P+ P+ SP+ P L G+ S+ P P Sbjct: 92 PLGTAPEAPTFLPNLI----GPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSV 147 Query: 642 SESTEKEPE---QDGPAAPADGSTVESLPRPLSPTK 674 +S+ P A A+ +V +L P++P++ Sbjct: 148 QKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSE 183 Score = 32.7 bits (73), Expect = 1.9 Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 14/94 (14%) Query: 781 LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEA 840 +P E + A + ELP P+ E + P ++ +V P P Sbjct: 1 MPGEATETVPATEQELPQPQAETAVLPM-------------SSALSVTAALGQPGPTLPP 47 Query: 841 P-SPGEEQVPPAPLPPASHPPATSTNKRTNLKKP 873 P SP +Q P + AS P+ ST T L+ P Sbjct: 48 PCSPAPQQCPLSAANQASPFPSPSTIASTPLEVP 81 Score = 30.4 bits (67), Expect = 9.5 Identities = 59/233 (25%), Positives = 87/233 (37%), Gaps = 44/233 (18%) Query: 413 PSVEGSVKQGTVSSQPVPFS-ALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPL 471 P+ E + Q + +P S AL T G +PPP +Q P S SP P Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFP- 68 Query: 472 GPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYP 531 P + +S E P+ S+G T LP + P +PT+ Sbjct: 69 SPSTIASTP--LEVPFPQSSSG-------TALPLG----------------TAPEAPTFL 103 Query: 532 P--AGPPAFPAGDSKPELPLTVAIRPFLAD--KGSRPQSPRKGPQTVNSSSIYSMYLQQA 587 P GPP PA L +A P +A KG+ S P + + + +S+ A Sbjct: 104 PNLIGPPISPAA-------LALA-SPMIAPTLKGTPSSS---APLALVALAPHSVQKSSA 152 Query: 588 TPPKNYQPAAHSALNKSVKAV-YGKPVLPS-GSTSPSPLPFLHGSLSTGTPQP 638 PP A+ +S + P+ PS T+ + +P GTP P Sbjct: 153 FPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP 205 >gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit 12A isoform a [Homo sapiens] Length = 1030 Score = 77.0 bits (188), Expect = 9e-14 Identities = 48/135 (35%), Positives = 77/135 (57%), Gaps = 5/135 (3%) Query: 868 TNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHN 927 T+L+ P +R +V+F+ A+ L A G+ D V ++++ D + N +G+T LH Sbjct: 22 TDLEPPVVKR--QKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQ 79 Query: 928 AVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISD 987 A + +VKFL++ G N+N D++GW PLH AASC + + + L+ GA + A S+ Sbjct: 80 ACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SE 138 Query: 988 IETAADKCEE--MEE 1000 +T D EE MEE Sbjct: 139 GDTPLDIAEEEAMEE 153 Score = 55.1 bits (131), Expect = 4e-07 Identities = 46/175 (26%), Positives = 78/175 (44%), Gaps = 8/175 (4%) Query: 836 PVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDA 895 P+ A S G + + +H A ++ T L E L+ N + ++A Sbjct: 109 PLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEA 168 Query: 896 SLEGEFDLVQRIIYEVEDPSKPND-----EGITPLHNAVCAGHHHIVKFLLDFGVNVNAA 950 + + E ++ R + + ND G T LH A G+ ++K L+ G +VN Sbjct: 169 ARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIK 228 Query: 951 DSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDI-ETAADKCEEMEEGYIQ 1004 D DGWTPLH AA C+ LV++ + ++ + +TA D +E GY++ Sbjct: 229 DYDGWTPLHAAAHWGKEEACRILVDNLCDM--EMVNKVGQTAFDVADEDILGYLE 281 >gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit 12A isoform a [Homo sapiens] Length = 1030 Score = 77.0 bits (188), Expect = 9e-14 Identities = 48/135 (35%), Positives = 77/135 (57%), Gaps = 5/135 (3%) Query: 868 TNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHN 927 T+L+ P +R +V+F+ A+ L A G+ D V ++++ D + N +G+T LH Sbjct: 22 TDLEPPVVKR--QKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQ 79 Query: 928 AVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISD 987 A + +VKFL++ G N+N D++GW PLH AASC + + + L+ GA + A S+ Sbjct: 80 ACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SE 138 Query: 988 IETAADKCEE--MEE 1000 +T D EE MEE Sbjct: 139 GDTPLDIAEEEAMEE 153 Score = 55.1 bits (131), Expect = 4e-07 Identities = 46/175 (26%), Positives = 78/175 (44%), Gaps = 8/175 (4%) Query: 836 PVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDA 895 P+ A S G + + +H A ++ T L E L+ N + ++A Sbjct: 109 PLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEA 168 Query: 896 SLEGEFDLVQRIIYEVEDPSKPND-----EGITPLHNAVCAGHHHIVKFLLDFGVNVNAA 950 + + E ++ R + + ND G T LH A G+ ++K L+ G +VN Sbjct: 169 ARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIK 228 Query: 951 DSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDI-ETAADKCEEMEEGYIQ 1004 D DGWTPLH AA C+ LV++ + ++ + +TA D +E GY++ Sbjct: 229 DYDGWTPLHAAAHWGKEEACRILVDNLCDM--EMVNKVGQTAFDVADEDILGYLE 281 >gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit 12B isoform b [Homo sapiens] Length = 998 Score = 76.6 bits (187), Expect = 1e-13 Identities = 42/115 (36%), Positives = 66/115 (57%), Gaps = 1/115 (0%) Query: 883 RVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLD 942 RVRF A+ L A G+ D V++++ D + N +G+T LH A + +VKFL++ Sbjct: 53 RVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVE 112 Query: 943 FGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEE 997 NVN D++GWTPLH AASC +++ + + GA++ S+ E +D EE Sbjct: 113 NRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASV-GIVNSEGEVPSDLAEE 166 Score = 49.3 bits (116), Expect = 2e-05 Identities = 22/56 (39%), Positives = 29/56 (51%) Query: 921 GITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVES 976 G T LH A G+ +++ L+ G +N D DGWTPLH AA C L E+ Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEA 272 >gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit 12B isoform a [Homo sapiens] Length = 982 Score = 76.6 bits (187), Expect = 1e-13 Identities = 42/115 (36%), Positives = 66/115 (57%), Gaps = 1/115 (0%) Query: 883 RVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLD 942 RVRF A+ L A G+ D V++++ D + N +G+T LH A + +VKFL++ Sbjct: 53 RVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVE 112 Query: 943 FGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEE 997 NVN D++GWTPLH AASC +++ + + GA++ S+ E +D EE Sbjct: 113 NRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASV-GIVNSEGEVPSDLAEE 166 Score = 49.3 bits (116), Expect = 2e-05 Identities = 22/56 (39%), Positives = 29/56 (51%) Query: 921 GITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVES 976 G T LH A G+ +++ L+ G +N D DGWTPLH AA C L E+ Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEA 272 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 72.0 bits (175), Expect = 3e-12 Identities = 129/572 (22%), Positives = 193/572 (33%), Gaps = 102/572 (17%) Query: 351 QVPSAGSFPVLGDPIKPQS----LSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVA 406 Q P G P+ G PQ+ L + +A+ ++K A+ ++K + S KP Sbjct: 250 QPPGTGK-PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308 Query: 407 GADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYP 466 K P+ + ++ P G T+ + G V PP+ G PP+ Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ---- 364 Query: 467 SPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTP--QPGSSQQIQQRISV 524 PLGP + + E +PS+ P + P G TP QPG Sbjct: 365 ---PLGPAKPPAQQTGSE----KPSSEQPGPKALAQPPGVGKTPAQQPG----------- 406 Query: 525 PPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYL 584 PA PP G KP +A +P L QSP K P + + Sbjct: 407 -------PAKPPTQQVGTPKP-----LAQQPGL-------QSPAKAPGPTKTP------V 441 Query: 585 QQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPS-PLPFLHGSLSTGTPQP---QP 640 QQ P K PA + K+ G PS P+ P P G QP +P Sbjct: 442 QQPGPGKI--PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP 499 Query: 641 PSE---STEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRK 697 PS+ ST+ P+Q GPA P+ + P P P P + A Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559 Query: 698 LANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT---LAGGMEGTPFYQPSPSQDFMGT 754 + +PL+ + + P + K + NT L E F + Q + + Sbjct: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619 Query: 755 LADVDNGNTNANGNLEELP--------------------PAQPTAPLPAEPAPSSDANDN 794 L N N +L E+ P+ P L P ++ A Sbjct: 620 LC-----GFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSK 674 Query: 795 ELPSPE---PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAP-------SPG 844 P P+ P++ P+ A P + PT PS A+ P P Sbjct: 675 SSPQPQQTSPKKDAAPKQDLSKA-PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733 Query: 845 EEQVPPAPLPPASHPPATSTNKRTNLKKPNSE 876 + P P P A K+ + KP ++ Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTD 765 Score = 61.6 bits (148), Expect = 4e-09 Identities = 99/461 (21%), Positives = 153/461 (33%), Gaps = 58/461 (12%) Query: 460 PSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQ 519 PS+ P+ S ERR+ ++ + GLP P PA +P Q++ Sbjct: 32 PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP---PAAAESPSMHRKQELD 88 Query: 520 QRISVPPSPTYPPAGPPAFPAGD---------SKPELPLTVAIRPFLADKGSRPQSPRKG 570 S P G PA P S+ +LP L + SR + Sbjct: 89 SSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEH 148 Query: 571 PQT--------VNSSSIYSMYLQQATPPK--NYQPAAHSALNKSVKAVYGKPVLPSG--- 617 + VN+ S S + + P + A+ K K V + P G Sbjct: 149 KSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208 Query: 618 ----STSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPT 673 P P+P G Q P + ++PE+ P G ++ PT Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ------GPT 262 Query: 674 KLTPIVHSPLRYQSDA------DLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLY 727 + H+ L Q DA + +R + P + I +P PG P Q+ + Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT-PGKPPAQQPGH 321 Query: 728 QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAP 787 ++ P P GT+ + L PA+P A P Sbjct: 322 EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381 Query: 788 SSDANDNELPSPEPEELICP----QTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP 843 SS+ P P+ L P +T Q PA+ V T Q P + A +P Sbjct: 382 SSE-------QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434 Query: 844 GEEQVP-----PAPLPPASHPPATSTNKRTNLKKPNSERTG 879 G + P P +P P ++ ++T KP S+ G Sbjct: 435 GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475 Score = 61.6 bits (148), Expect = 4e-09 Identities = 149/723 (20%), Positives = 246/723 (34%), Gaps = 126/723 (17%) Query: 243 EDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQ--QKELLNKRN 300 E+ K + GF S L+ ++V K +L ++ +QE+ +K Q+ QKE Sbjct: 146 EEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEG 205 Query: 301 MEVAMMDKRISELRERLYGKKIQLNRVNGTS---SPQSPLSTSGRVAAVGPYIQVPSA-- 355 + + ++ + + G + +GT S Q P + G IQ P+ Sbjct: 206 IIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTP 265 Query: 356 ----GSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWK 411 P+ D +PQ+ S + P ++Q + P Q G + Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK-PPAQQPGHEKS 324 Query: 412 DPSVEGSVKQGTVSSQPV---------PFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSY 462 P Q + ++P+ P G T+ P +G PP G + P S Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384 Query: 463 GTYPSPT--PLGPGSTSSLER------RKEGSLPRPSAGLPSRQRPTLLPATGSTPQ--- 511 P P G G T + + ++ P+P A P Q P P TP Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444 Query: 512 -----------PGSSQQIQQRISVPPS---------PTYP-PAGPPAFPAGDSKPELPLT 550 PG + Q + PPS P P PA PP G +KP Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504 Query: 551 VAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYG 610 + +P G SP++ T S A P +P+A + + G Sbjct: 505 GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564 Query: 611 KPVLPSGSTSPSPLPFLHGSLSTGTP----------QPQPPSESTEKEPE---------- 650 KP+ P + + P G T P P+ + +T E + Sbjct: 565 KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN 624 Query: 651 ----------------QDGPAAPADGSTVESLPRP---LSPTKLTPIV--HSPLRYQSDA 689 Q A D + V S P+P +P T V SP Q+ Sbjct: 625 PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP 684 Query: 690 DLEAL-RRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPS-P 747 +A ++ L+ AP P K + +P G P+ + ++L+ + P +PS P Sbjct: 685 KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS---KPAPPKEPSVP 741 Query: 748 SQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPE-PEELIC 806 S+ +AD +P P +P ++ + P+ P + Sbjct: 742 SEQDKAPVAD-----------------DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784 Query: 807 PQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPA---SHPPATS 863 Q +T P + + + ++ P P E SP + + P P + SHP +S Sbjct: 785 SQAEEKTTPPLKTD-----SAKPSQSFP-PTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838 Query: 864 TNK 866 +K Sbjct: 839 ESK 841 Score = 52.0 bits (123), Expect = 3e-06 Identities = 92/392 (23%), Positives = 129/392 (32%), Gaps = 91/392 (23%) Query: 489 RPSAGLPSRQRPTLLPAT-GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPEL 547 +P +P +Q P P TP+ SSQQ ++ S PP P GP P D +L Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA-KL 272 Query: 548 PLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKA 607 PL SRPQ+ K V S+ Sbjct: 273 PLQ--------RDASRPQT--KQADIVRGESV---------------------------- 294 Query: 608 VYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLP 667 KP LPS S P P TP +PP++ E Q GPA P + + P Sbjct: 295 ---KPSLPSPSKPPIQQP---------TPG-KPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341 Query: 668 RPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLY 727 P + P V P + A + L A P ++ S GP K L Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPA------QPLGPAKPPAQQTGSEKPSSEQPGP---KALA 392 Query: 728 QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAP 787 Q G+ TP QP P A +++ +P A P +P Sbjct: 393 Q-----PPGVGKTPAQQPGP-----------------AKPPTQQVGTPKPLAQQPGLQSP 430 Query: 788 SSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQ 847 + + P +P P Q A P + + Q+P P P +Q Sbjct: 431 AKAPGPTKTPVQQPGPGKIPA---QQAGPGKTSAQQTGPTKPPSQLPGPAKPPP----QQ 483 Query: 848 VPPAPLPPASHPPATSTNKRTNLKKPNSERTG 879 PA PP A +++ KP ++ G Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG 515 Score = 50.8 bits (120), Expect = 7e-06 Identities = 89/416 (21%), Positives = 146/416 (35%), Gaps = 60/416 (14%) Query: 466 PSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPA-TGSTPQPGSSQQIQQRISV 524 P P P ++ ++ P P P ++PTL + + QP + + + Sbjct: 677 PQPQQTSPKKDAA-PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSK--PA 733 Query: 525 PPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYL 584 PP P+ P D KP+ P V L S P + SS + S Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP-----DIPSSKVQSQAE 788 Query: 585 QQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSES 644 ++ TPP +K KP T PF ++ P+P S+S Sbjct: 789 EKTTPP--------------LKTDSAKPSQSFPPTGEKVSPFDSKAI------PRPASDS 828 Query: 645 TEKEPEQDGPAAPADGST-VESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPR 703 K GP++ + G V+ + + P K + + + DA PR Sbjct: 829 --KIISHPGPSSESKGQKQVDPVQKKEEPKK----AQTKMSPKPDAKPMPKGSPTPPGPR 882 Query: 704 PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQD-----FMGTLADV 758 P ++ T + P P Q +RF+ G + P QP+ Q+ G A + Sbjct: 883 PTAGQTVPTPQQSPK-PQEQS---RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASI 938 Query: 759 DNGNTNANGNLEELPPAQPTAP-LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPA 817 + +N + P + P P + AP+ PS P P++T Q A PA Sbjct: 939 FSQASNLISTAGQPGPHSQSGPGAPMKQAPA--------PSQPPTSQGPPKSTGQ-APPA 989 Query: 818 EDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKP 873 ++P ++ +P AE P EQ P P + ++ +P Sbjct: 990 P-----AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040 Score = 50.1 bits (118), Expect = 1e-05 Identities = 95/457 (20%), Positives = 155/457 (33%), Gaps = 83/457 (18%) Query: 396 SSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG 455 S SS +P Q + KD + + + + +P P K PP + Sbjct: 673 SKSSPQPQQTSPK--KDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS 730 Query: 456 KQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSS 515 K PP + PS P + ++ K+ + +P+ L S T P P Sbjct: 731 KPAPPKEPSVPSEQDKAPVAD---DKPKQPKMVKPTTDLVSSSSATTKP---DIPSSKVQ 784 Query: 516 QQIQQRISVP-------PSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPR 568 Q +++ + P PS ++PP G P DSK +P + ++ G P S Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-DSKA-IPRPASDSKIISHPG--PSSES 840 Query: 569 KGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLH 628 KG + V+ +Q+ PK Q K KP+ T P P P Sbjct: 841 KGQKQVDP-------VQKKEEPKKAQ-------TKMSPKPDAKPMPKGSPTPPGPRPTAG 886 Query: 629 GSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSD 688 ++ T P+P +S L I +P + Q Sbjct: 887 QTVPTPQQSPKPQEQSRR------------------------FSLNLGSITDAP-KSQPT 921 Query: 689 ADLEALRRKLANAPRPL-KKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQ-PS 746 E + KL + + S++ G GP+ Q G P Q P+ Sbjct: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ------------SGPGAPMKQAPA 969 Query: 747 PSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELIC 806 PSQ G + G + PPA P +P + + A + P E + Sbjct: 970 PSQ------PPTSQGPPKSTG---QAPPA-PAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019 Query: 807 PQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP 843 T + P +D+ + A P +P+ + ++P P Sbjct: 1020 RTETEKKPPPIKDSKSLTAE-PQKAVLPTKLEKSPKP 1055 Score = 39.3 bits (90), Expect = 0.020 Identities = 56/231 (24%), Positives = 81/231 (35%), Gaps = 43/231 (18%) Query: 495 PSRQRPTLLPATGSTP---QPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTV 551 P+ Q P+ P+ S P +P + PP P PP PP P P LP Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431 Query: 552 AIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVY-- 609 + +P + K L A+P P + AV Sbjct: 2432 SPKPTILPKKK---------------------LTVASPVTTATPLFDAVTTLETTAVLRS 2470 Query: 610 -GKPVLPSGSTSPSPLPFLHGSLSTG---TPQPQPPSESTEKEPEQDGPAAPADGSTVES 665 G PV +T+P P+P S+ +G T +P+P K P P P +T + Sbjct: 2471 NGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEP-----SKPPIAPKPVIPQLPTTTQK 2525 Query: 666 LPRPL--SPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEP 714 P + PT L+ L + AD KL + PL S+ + P Sbjct: 2526 -PTDIHPKPTGLSLTSSMTLNLVTSADY-----KLPSPTSPLSPHSNKSSP 2570 Score = 38.5 bits (88), Expect = 0.035 Identities = 34/133 (25%), Positives = 66/133 (49%), Gaps = 18/133 (13%) Query: 137 RQQQQIENQQQMLVA---KEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKI 193 +QQQQ++ ++++L K+QR + ER++ Q E EK+ K KL+++ Sbjct: 3209 KQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQK--------KLEEL 3260 Query: 194 RAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQL-EDLKKGKLNG 252 ++M+ + + + E + M QE + Q + ++ QL QQL + L++ K+ Sbjct: 3261 QSMKQHLLFQQ------EEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQ 3314 Query: 253 FQSYNGKLTGPAA 265 YN +G A+ Sbjct: 3315 IYQYNYDPSGTAS 3327 Score = 32.7 bits (73), Expect = 1.9 Identities = 35/156 (22%), Positives = 51/156 (32%), Gaps = 17/156 (10%) Query: 773 PPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQ 832 PP P P P P P + P+ P++ + + TA P D + T Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRS 2470 Query: 833 IPSPVAEAPSPGEEQVPPAP-----------LPPASHPPATSTNKRTNLKKPNSERTGHG 881 PV + VPP P P S PP L + T Sbjct: 2471 NGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD-- 2528 Query: 882 LRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKP 917 + P L L +S+ +LV Y++ P+ P Sbjct: 2529 --IHPKPTGLSLTSSM--TLNLVTSADYKLPSPTSP 2560 Score = 32.0 bits (71), Expect = 3.3 Identities = 28/104 (26%), Positives = 34/104 (32%), Gaps = 3/104 (2%) Query: 773 PPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEP---AEDNNNNVATVPT 829 PP P P P P P P P+ I P+ A P A + V T+ T Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464 Query: 830 TEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKP 873 T + S PP P P+S P R KP Sbjct: 2465 TAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKP 2508 Score = 31.2 bits (69), Expect = 5.6 Identities = 56/226 (24%), Positives = 81/226 (35%), Gaps = 31/226 (13%) Query: 417 GSVKQGTVSSQPVPF---SALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGP 473 GS ++ ++P PF S+L + +P PPP P PP P P P P Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQP-----PPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433 Query: 474 GSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPA 533 T +++ + P +A P T L T G RI P PP Sbjct: 2434 KPTILPKKKLTVASPVTTA-TPLFDAVTTLETTAVLRSNGLP---VTRICTTAPPPVPPK 2489 Query: 534 GPPAFPAG-----DSKPELPLTVAIRPFLADKGSRPQSPRK-GPQTVNSSSIYSMYLQQA 587 P + P+G +P P +A +P + + Q P P+ S SM L Sbjct: 2490 -PSSIPSGLVFTHRPEPSKP-PIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLV 2547 Query: 588 TPPKNYQPAAHSAL-----------NKSVKAVYGKPVLPSGSTSPS 622 T P+ S L +KS+ Y LPS +P+ Sbjct: 2548 TSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPT 2593 Score = 30.4 bits (67), Expect = 9.5 Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 6/74 (8%) Query: 794 NELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPL 853 ++LPS P P A+P ++ + P P P P PP PL Sbjct: 2374 SQLPSGSPSVSSLP------AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427 Query: 854 PPASHPPATSTNKR 867 PP + P T K+ Sbjct: 2428 PPPTSPKPTILPKK 2441 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 72.0 bits (175), Expect = 3e-12 Identities = 129/572 (22%), Positives = 193/572 (33%), Gaps = 102/572 (17%) Query: 351 QVPSAGSFPVLGDPIKPQS----LSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVA 406 Q P G P+ G PQ+ L + +A+ ++K A+ ++K + S KP Sbjct: 250 QPPGTGK-PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308 Query: 407 GADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYP 466 K P+ + ++ P G T+ + G V PP+ G PP+ Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ---- 364 Query: 467 SPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTP--QPGSSQQIQQRISV 524 PLGP + + E +PS+ P + P G TP QPG Sbjct: 365 ---PLGPAKPPAQQTGSE----KPSSEQPGPKALAQPPGVGKTPAQQPG----------- 406 Query: 525 PPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYL 584 PA PP G KP +A +P L QSP K P + + Sbjct: 407 -------PAKPPTQQVGTPKP-----LAQQPGL-------QSPAKAPGPTKTP------V 441 Query: 585 QQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPS-PLPFLHGSLSTGTPQP---QP 640 QQ P K PA + K+ G PS P+ P P G QP +P Sbjct: 442 QQPGPGKI--PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP 499 Query: 641 PSE---STEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRK 697 PS+ ST+ P+Q GPA P+ + P P P P + A Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559 Query: 698 LANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT---LAGGMEGTPFYQPSPSQDFMGT 754 + +PL+ + + P + K + NT L E F + Q + + Sbjct: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619 Query: 755 LADVDNGNTNANGNLEELP--------------------PAQPTAPLPAEPAPSSDANDN 794 L N N +L E+ P+ P L P ++ A Sbjct: 620 LC-----GFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSK 674 Query: 795 ELPSPE---PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAP-------SPG 844 P P+ P++ P+ A P + PT PS A+ P P Sbjct: 675 SSPQPQQTSPKKDAAPKQDLSKA-PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733 Query: 845 EEQVPPAPLPPASHPPATSTNKRTNLKKPNSE 876 + P P P A K+ + KP ++ Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTD 765 Score = 61.6 bits (148), Expect = 4e-09 Identities = 99/461 (21%), Positives = 153/461 (33%), Gaps = 58/461 (12%) Query: 460 PSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQ 519 PS+ P+ S ERR+ ++ + GLP P PA +P Q++ Sbjct: 32 PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP---PAAAESPSMHRKQELD 88 Query: 520 QRISVPPSPTYPPAGPPAFPAGD---------SKPELPLTVAIRPFLADKGSRPQSPRKG 570 S P G PA P S+ +LP L + SR + Sbjct: 89 SSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEH 148 Query: 571 PQT--------VNSSSIYSMYLQQATPPK--NYQPAAHSALNKSVKAVYGKPVLPSG--- 617 + VN+ S S + + P + A+ K K V + P G Sbjct: 149 KSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208 Query: 618 ----STSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPT 673 P P+P G Q P + ++PE+ P G ++ PT Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ------GPT 262 Query: 674 KLTPIVHSPLRYQSDA------DLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLY 727 + H+ L Q DA + +R + P + I +P PG P Q+ + Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT-PGKPPAQQPGH 321 Query: 728 QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAP 787 ++ P P GT+ + L PA+P A P Sbjct: 322 EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381 Query: 788 SSDANDNELPSPEPEELICP----QTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP 843 SS+ P P+ L P +T Q PA+ V T Q P + A +P Sbjct: 382 SSE-------QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434 Query: 844 GEEQVP-----PAPLPPASHPPATSTNKRTNLKKPNSERTG 879 G + P P +P P ++ ++T KP S+ G Sbjct: 435 GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475 Score = 61.6 bits (148), Expect = 4e-09 Identities = 149/723 (20%), Positives = 246/723 (34%), Gaps = 126/723 (17%) Query: 243 EDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQ--QKELLNKRN 300 E+ K + GF S L+ ++V K +L ++ +QE+ +K Q+ QKE Sbjct: 146 EEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEG 205 Query: 301 MEVAMMDKRISELRERLYGKKIQLNRVNGTS---SPQSPLSTSGRVAAVGPYIQVPSA-- 355 + + ++ + + G + +GT S Q P + G IQ P+ Sbjct: 206 IIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTP 265 Query: 356 ----GSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWK 411 P+ D +PQ+ S + P ++Q + P Q G + Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK-PPAQQPGHEKS 324 Query: 412 DPSVEGSVKQGTVSSQPV---------PFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSY 462 P Q + ++P+ P G T+ P +G PP G + P S Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384 Query: 463 GTYPSPT--PLGPGSTSSLER------RKEGSLPRPSAGLPSRQRPTLLPATGSTPQ--- 511 P P G G T + + ++ P+P A P Q P P TP Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444 Query: 512 -----------PGSSQQIQQRISVPPS---------PTYP-PAGPPAFPAGDSKPELPLT 550 PG + Q + PPS P P PA PP G +KP Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504 Query: 551 VAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYG 610 + +P G SP++ T S A P +P+A + + G Sbjct: 505 GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564 Query: 611 KPVLPSGSTSPSPLPFLHGSLSTGTP----------QPQPPSESTEKEPE---------- 650 KP+ P + + P G T P P+ + +T E + Sbjct: 565 KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN 624 Query: 651 ----------------QDGPAAPADGSTVESLPRP---LSPTKLTPIV--HSPLRYQSDA 689 Q A D + V S P+P +P T V SP Q+ Sbjct: 625 PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP 684 Query: 690 DLEAL-RRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPS-P 747 +A ++ L+ AP P K + +P G P+ + ++L+ + P +PS P Sbjct: 685 KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS---KPAPPKEPSVP 741 Query: 748 SQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPE-PEELIC 806 S+ +AD +P P +P ++ + P+ P + Sbjct: 742 SEQDKAPVAD-----------------DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784 Query: 807 PQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPA---SHPPATS 863 Q +T P + + + ++ P P E SP + + P P + SHP +S Sbjct: 785 SQAEEKTTPPLKTD-----SAKPSQSFP-PTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838 Query: 864 TNK 866 +K Sbjct: 839 ESK 841 Score = 52.0 bits (123), Expect = 3e-06 Identities = 92/392 (23%), Positives = 129/392 (32%), Gaps = 91/392 (23%) Query: 489 RPSAGLPSRQRPTLLPAT-GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPEL 547 +P +P +Q P P TP+ SSQQ ++ S PP P GP P D +L Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA-KL 272 Query: 548 PLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKA 607 PL SRPQ+ K V S+ Sbjct: 273 PLQ--------RDASRPQT--KQADIVRGESV---------------------------- 294 Query: 608 VYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLP 667 KP LPS S P P TP +PP++ E Q GPA P + + P Sbjct: 295 ---KPSLPSPSKPPIQQP---------TPG-KPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341 Query: 668 RPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLY 727 P + P V P + A + L A P ++ S GP K L Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPA------QPLGPAKPPAQQTGSEKPSSEQPGP---KALA 392 Query: 728 QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAP 787 Q G+ TP QP P A +++ +P A P +P Sbjct: 393 Q-----PPGVGKTPAQQPGP-----------------AKPPTQQVGTPKPLAQQPGLQSP 430 Query: 788 SSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQ 847 + + P +P P Q A P + + Q+P P P +Q Sbjct: 431 AKAPGPTKTPVQQPGPGKIPA---QQAGPGKTSAQQTGPTKPPSQLPGPAKPPP----QQ 483 Query: 848 VPPAPLPPASHPPATSTNKRTNLKKPNSERTG 879 PA PP A +++ KP ++ G Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG 515 Score = 50.8 bits (120), Expect = 7e-06 Identities = 89/416 (21%), Positives = 146/416 (35%), Gaps = 60/416 (14%) Query: 466 PSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPA-TGSTPQPGSSQQIQQRISV 524 P P P ++ ++ P P P ++PTL + + QP + + + Sbjct: 677 PQPQQTSPKKDAA-PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSK--PA 733 Query: 525 PPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYL 584 PP P+ P D KP+ P V L S P + SS + S Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP-----DIPSSKVQSQAE 788 Query: 585 QQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSES 644 ++ TPP +K KP T PF ++ P+P S+S Sbjct: 789 EKTTPP--------------LKTDSAKPSQSFPPTGEKVSPFDSKAI------PRPASDS 828 Query: 645 TEKEPEQDGPAAPADGST-VESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPR 703 K GP++ + G V+ + + P K + + + DA PR Sbjct: 829 --KIISHPGPSSESKGQKQVDPVQKKEEPKK----AQTKMSPKPDAKPMPKGSPTPPGPR 882 Query: 704 PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQD-----FMGTLADV 758 P ++ T + P P Q +RF+ G + P QP+ Q+ G A + Sbjct: 883 PTAGQTVPTPQQSPK-PQEQS---RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASI 938 Query: 759 DNGNTNANGNLEELPPAQPTAP-LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPA 817 + +N + P + P P + AP+ PS P P++T Q A PA Sbjct: 939 FSQASNLISTAGQPGPHSQSGPGAPMKQAPA--------PSQPPTSQGPPKSTGQ-APPA 989 Query: 818 EDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKP 873 ++P ++ +P AE P EQ P P + ++ +P Sbjct: 990 P-----AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040 Score = 50.1 bits (118), Expect = 1e-05 Identities = 95/457 (20%), Positives = 155/457 (33%), Gaps = 83/457 (18%) Query: 396 SSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG 455 S SS +P Q + KD + + + + +P P K PP + Sbjct: 673 SKSSPQPQQTSPK--KDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS 730 Query: 456 KQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSS 515 K PP + PS P + ++ K+ + +P+ L S T P P Sbjct: 731 KPAPPKEPSVPSEQDKAPVAD---DKPKQPKMVKPTTDLVSSSSATTKP---DIPSSKVQ 784 Query: 516 QQIQQRISVP-------PSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPR 568 Q +++ + P PS ++PP G P DSK +P + ++ G P S Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-DSKA-IPRPASDSKIISHPG--PSSES 840 Query: 569 KGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLH 628 KG + V+ +Q+ PK Q K KP+ T P P P Sbjct: 841 KGQKQVDP-------VQKKEEPKKAQ-------TKMSPKPDAKPMPKGSPTPPGPRPTAG 886 Query: 629 GSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSD 688 ++ T P+P +S L I +P + Q Sbjct: 887 QTVPTPQQSPKPQEQSRR------------------------FSLNLGSITDAP-KSQPT 921 Query: 689 ADLEALRRKLANAPRPL-KKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQ-PS 746 E + KL + + S++ G GP+ Q G P Q P+ Sbjct: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ------------SGPGAPMKQAPA 969 Query: 747 PSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELIC 806 PSQ G + G + PPA P +P + + A + P E + Sbjct: 970 PSQ------PPTSQGPPKSTG---QAPPA-PAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019 Query: 807 PQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP 843 T + P +D+ + A P +P+ + ++P P Sbjct: 1020 RTETEKKPPPIKDSKSLTAE-PQKAVLPTKLEKSPKP 1055 Score = 39.3 bits (90), Expect = 0.020 Identities = 56/231 (24%), Positives = 81/231 (35%), Gaps = 43/231 (18%) Query: 495 PSRQRPTLLPATGSTP---QPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTV 551 P+ Q P+ P+ S P +P + PP P PP PP P P LP Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431 Query: 552 AIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVY-- 609 + +P + K L A+P P + AV Sbjct: 2432 SPKPTILPKKK---------------------LTVASPVTTATPLFDAVTTLETTAVLRS 2470 Query: 610 -GKPVLPSGSTSPSPLPFLHGSLSTG---TPQPQPPSESTEKEPEQDGPAAPADGSTVES 665 G PV +T+P P+P S+ +G T +P+P K P P P +T + Sbjct: 2471 NGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEP-----SKPPIAPKPVIPQLPTTTQK 2525 Query: 666 LPRPL--SPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEP 714 P + PT L+ L + AD KL + PL S+ + P Sbjct: 2526 -PTDIHPKPTGLSLTSSMTLNLVTSADY-----KLPSPTSPLSPHSNKSSP 2570 Score = 38.5 bits (88), Expect = 0.035 Identities = 34/133 (25%), Positives = 66/133 (49%), Gaps = 18/133 (13%) Query: 137 RQQQQIENQQQMLVA---KEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKI 193 +QQQQ++ ++++L K+QR + ER++ Q E EK+ K KL+++ Sbjct: 3209 KQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQK--------KLEEL 3260 Query: 194 RAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQL-EDLKKGKLNG 252 ++M+ + + + E + M QE + Q + ++ QL QQL + L++ K+ Sbjct: 3261 QSMKQHLLFQQ------EEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQ 3314 Query: 253 FQSYNGKLTGPAA 265 YN +G A+ Sbjct: 3315 IYQYNYDPSGTAS 3327 Score = 32.7 bits (73), Expect = 1.9 Identities = 35/156 (22%), Positives = 51/156 (32%), Gaps = 17/156 (10%) Query: 773 PPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQ 832 PP P P P P P + P+ P++ + + TA P D + T Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRS 2470 Query: 833 IPSPVAEAPSPGEEQVPPAP-----------LPPASHPPATSTNKRTNLKKPNSERTGHG 881 PV + VPP P P S PP L + T Sbjct: 2471 NGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD-- 2528 Query: 882 LRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKP 917 + P L L +S+ +LV Y++ P+ P Sbjct: 2529 --IHPKPTGLSLTSSM--TLNLVTSADYKLPSPTSP 2560 Score = 32.0 bits (71), Expect = 3.3 Identities = 28/104 (26%), Positives = 34/104 (32%), Gaps = 3/104 (2%) Query: 773 PPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEP---AEDNNNNVATVPT 829 PP P P P P P P P+ I P+ A P A + V T+ T Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464 Query: 830 TEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKP 873 T + S PP P P+S P R KP Sbjct: 2465 TAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKP 2508 Score = 31.2 bits (69), Expect = 5.6 Identities = 56/226 (24%), Positives = 81/226 (35%), Gaps = 31/226 (13%) Query: 417 GSVKQGTVSSQPVPF---SALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGP 473 GS ++ ++P PF S+L + +P PPP P PP P P P P Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQP-----PPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433 Query: 474 GSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPA 533 T +++ + P +A P T L T G RI P PP Sbjct: 2434 KPTILPKKKLTVASPVTTA-TPLFDAVTTLETTAVLRSNGLP---VTRICTTAPPPVPPK 2489 Query: 534 GPPAFPAG-----DSKPELPLTVAIRPFLADKGSRPQSPRK-GPQTVNSSSIYSMYLQQA 587 P + P+G +P P +A +P + + Q P P+ S SM L Sbjct: 2490 -PSSIPSGLVFTHRPEPSKP-PIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLV 2547 Query: 588 TPPKNYQPAAHSAL-----------NKSVKAVYGKPVLPSGSTSPS 622 T P+ S L +KS+ Y LPS +P+ Sbjct: 2548 TSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPT 2593 Score = 30.4 bits (67), Expect = 9.5 Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 6/74 (8%) Query: 794 NELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPL 853 ++LPS P P A+P ++ + P P P P PP PL Sbjct: 2374 SQLPSGSPSVSSLP------AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427 Query: 854 PPASHPPATSTNKR 867 PP + P T K+ Sbjct: 2428 PPPTSPKPTILPKK 2441 >gi|20270347 ankyrin repeat domain 54 [Homo sapiens] Length = 300 Score = 70.9 bits (172), Expect = 6e-12 Identities = 42/120 (35%), Positives = 64/120 (53%), Gaps = 3/120 (2%) Query: 889 LALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVN 948 L L D++ + + VQ+++ + DP +D+G T LH A C G+ IV+ LLD G + N Sbjct: 111 LKRLRDSANANDVETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPN 170 Query: 949 AADSDGWTPLHCAASCNSVHLCKQLVESGAAIFA---STISDIETAADKCEEMEEGYIQC 1005 D G TPLH AA N V + L+ GA + A + + + A K ++EG+ QC Sbjct: 171 QRDGLGNTPLHLAACTNHVPVITTLLRGGARVDALDRAGRTPLHLAKSKLNILQEGHAQC 230 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 68.9 bits (167), Expect = 2e-11 Identities = 112/462 (24%), Positives = 169/462 (36%), Gaps = 62/462 (13%) Query: 435 GPTEKPGIEIGKVPP---PIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPS 491 G ++P G+ P I G+ P + T + + S+ + ++E S P S Sbjct: 33 GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS 92 Query: 492 AGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTV 551 RQR + T + S + Q IS P SP+ + DS+ + Sbjct: 93 N---KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEG-----ESSDSR-SVNDEG 143 Query: 552 AIRPFLADKGSRPQSPR-KGPQTVNSSSIYSMYLQ--QATPPKNYQPAAHSALNKSVKAV 608 + P D+ +R SP PQ S S S Q QA PP P + S A Sbjct: 144 SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS--AP 201 Query: 609 YGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPR 668 G P LP+ P P P S + PQ P + +P+ P AP + ++ P Sbjct: 202 PGTPQLPT----PGPTP----SATAVPPQGSPTASQAPNQPQ--APTAPVPHTHIQQAPA 251 Query: 669 PLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQK---L 725 L P + P H P L+ L P + + +GP GP+ + L Sbjct: 252 -LHPQR-PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL-HGQGPPGPHSLQAGPL 308 Query: 726 LY-----QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNL----EELPPAQ 776 L Q F +G SP+ + T + + + LPPA Sbjct: 309 LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 368 Query: 777 ---------PTAPLPAEPAPSSDANDNELPSPEPEEL---------ICPQTTHQTAEPAE 818 PT P+P PAP + + L P P + + P ++ T P Sbjct: 369 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 428 Query: 819 DNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPP 860 + + +P ++ +PS A+ P G Q P PPASHPP Sbjct: 429 AHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPP 468 Score = 52.0 bits (123), Expect = 3e-06 Identities = 110/448 (24%), Positives = 146/448 (32%), Gaps = 55/448 (12%) Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449 P+ + N S S Q + P+++ S P + PT P VPP Sbjct: 162 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP 221 Query: 450 PIPGVGKQLP--PSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507 Q P P T P P + + +R P P PS P L P TG Sbjct: 222 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH---PS-PHPPLQPLTG 277 Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSP 567 S QP + Q PP P GP + AG P L G PQ Sbjct: 278 SAGQPSAPSHAQ-----PPLHGQGPPGPHSLQAG-------------PLLQHPGP-PQPF 318 Query: 568 RKGPQTVNSSSIYSMYLQQATPPKNYQ-PAAHSALNKSVKAVYGKPVLPSGSTSPSPLPF 626 PQ + A P + Q PA+ SAL +S + +P+ P+PL Sbjct: 319 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPREQPL------PPAPLAM 371 Query: 627 LHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRP--LSPTKLTPIVHSPLR 684 H TP PQ P+ K P + P+ S +LP P L P H P Sbjct: 372 PHIKPPPTTPIPQLPAPQAHKHPPH--LSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 429 Query: 685 YQSDADLEALRRKLANAPRP---LKKRSSITEPEGPGGPN------IQKLLYQRFNTLAG 735 + L + L ++P L + ++ P P Q Q G Sbjct: 430 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 489 Query: 736 GMEGTPFYQPSPSQDFMGTLADVD--------NGNTNANGNLEELPPAQ-PTAPLPAEPA 786 TP PS S G +G + A G+ LP Q L Sbjct: 490 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 549 Query: 787 PSSDANDNELPSPEPEELICPQTTHQTA 814 P S PSPEP + P Q+A Sbjct: 550 PESPPPPPRSPSPEPTVVDTPSHASQSA 577 Score = 38.9 bits (89), Expect = 0.027 Identities = 62/230 (26%), Positives = 81/230 (35%), Gaps = 44/230 (19%) Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390 S Q+PL TS A +Q+P++ S P + Q L A A P Sbjct: 325 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM------------P 372 Query: 391 TLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVP-----FSALGPTEKPGIEIG 445 +K ++ + + A P + G ++ P P S+L P Sbjct: 373 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-- 430 Query: 446 KVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPA 505 PPP+ QL P PS PG T S +LP P A P PT L Sbjct: 431 --PPPL-----QLMPQSQPLPSSPAQPPGLTQSQ------NLPPPPASHP----PTGLHQ 473 Query: 506 TGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP 555 PQP Q VP P PP PP P+ + P P T A P Sbjct: 474 VA--PQP----PFAQHPFVPGGP--PPITPPTCPSTSTPPAGPGTSAQPP 515 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 68.9 bits (167), Expect = 2e-11 Identities = 112/462 (24%), Positives = 169/462 (36%), Gaps = 62/462 (13%) Query: 435 GPTEKPGIEIGKVPP---PIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPS 491 G ++P G+ P I G+ P + T + + S+ + ++E S P S Sbjct: 587 GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS 646 Query: 492 AGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTV 551 RQR + T + S + Q IS P SP+ + DS+ + Sbjct: 647 N---KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEG-----ESSDSR-SVNDEG 697 Query: 552 AIRPFLADKGSRPQSPR-KGPQTVNSSSIYSMYLQ--QATPPKNYQPAAHSALNKSVKAV 608 + P D+ +R SP PQ S S S Q QA PP P + S A Sbjct: 698 SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS--AP 755 Query: 609 YGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPR 668 G P LP+ P P P S + PQ P + +P+ P AP + ++ P Sbjct: 756 PGTPQLPT----PGPTP----SATAVPPQGSPTASQAPNQPQ--APTAPVPHTHIQQAPA 805 Query: 669 PLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQK---L 725 L P + P H P L+ L P + + +GP GP+ + L Sbjct: 806 -LHPQR-PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL-HGQGPPGPHSLQAGPL 862 Query: 726 LY-----QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNL----EELPPAQ 776 L Q F +G SP+ + T + + + LPPA Sbjct: 863 LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922 Query: 777 ---------PTAPLPAEPAPSSDANDNELPSPEPEEL---------ICPQTTHQTAEPAE 818 PT P+P PAP + + L P P + + P ++ T P Sbjct: 923 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982 Query: 819 DNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPP 860 + + +P ++ +PS A+ P G Q P PPASHPP Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPP 1022 Score = 52.0 bits (123), Expect = 3e-06 Identities = 110/448 (24%), Positives = 146/448 (32%), Gaps = 55/448 (12%) Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449 P+ + N S S Q + P+++ S P + PT P VPP Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP 775 Query: 450 PIPGVGKQLP--PSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507 Q P P T P P + + +R P P PS P L P TG Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH---PS-PHPPLQPLTG 831 Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSP 567 S QP + Q PP P GP + AG P L G PQ Sbjct: 832 SAGQPSAPSHAQ-----PPLHGQGPPGPHSLQAG-------------PLLQHPGP-PQPF 872 Query: 568 RKGPQTVNSSSIYSMYLQQATPPKNYQ-PAAHSALNKSVKAVYGKPVLPSGSTSPSPLPF 626 PQ + A P + Q PA+ SAL +S + +P+ P+PL Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPREQPL------PPAPLAM 925 Query: 627 LHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRP--LSPTKLTPIVHSPLR 684 H TP PQ P+ K P + P+ S +LP P L P H P Sbjct: 926 PHIKPPPTTPIPQLPAPQAHKHPPH--LSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 983 Query: 685 YQSDADLEALRRKLANAPRP---LKKRSSITEPEGPGGPN------IQKLLYQRFNTLAG 735 + L + L ++P L + ++ P P Q Q G Sbjct: 984 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043 Query: 736 GMEGTPFYQPSPSQDFMGTLADVD--------NGNTNANGNLEELPPAQ-PTAPLPAEPA 786 TP PS S G +G + A G+ LP Q L Sbjct: 1044 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 1103 Query: 787 PSSDANDNELPSPEPEELICPQTTHQTA 814 P S PSPEP + P Q+A Sbjct: 1104 PESPPPPPRSPSPEPTVVDTPSHASQSA 1131 Score = 38.9 bits (89), Expect = 0.027 Identities = 62/230 (26%), Positives = 81/230 (35%), Gaps = 44/230 (19%) Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390 S Q+PL TS A +Q+P++ S P + Q L A A P Sbjct: 879 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM------------P 926 Query: 391 TLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVP-----FSALGPTEKPGIEIG 445 +K ++ + + A P + G ++ P P S+L P Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-- 984 Query: 446 KVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPA 505 PPP+ QL P PS PG T S +LP P A P PT L Sbjct: 985 --PPPL-----QLMPQSQPLPSSPAQPPGLTQSQ------NLPPPPASHP----PTGLHQ 1027 Query: 506 TGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP 555 PQP Q VP P PP PP P+ + P P T A P Sbjct: 1028 VA--PQP----PFAQHPFVPGGP--PPITPPTCPSTSTPPAGPGTSAQPP 1069 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 68.9 bits (167), Expect = 2e-11 Identities = 112/462 (24%), Positives = 169/462 (36%), Gaps = 62/462 (13%) Query: 435 GPTEKPGIEIGKVPP---PIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPS 491 G ++P G+ P I G+ P + T + + S+ + ++E S P S Sbjct: 587 GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS 646 Query: 492 AGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTV 551 RQR + T + S + Q IS P SP+ + DS+ + Sbjct: 647 N---KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEG-----ESSDSR-SVNDEG 697 Query: 552 AIRPFLADKGSRPQSPR-KGPQTVNSSSIYSMYLQ--QATPPKNYQPAAHSALNKSVKAV 608 + P D+ +R SP PQ S S S Q QA PP P + S A Sbjct: 698 SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS--AP 755 Query: 609 YGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPR 668 G P LP+ P P P S + PQ P + +P+ P AP + ++ P Sbjct: 756 PGTPQLPT----PGPTP----SATAVPPQGSPTASQAPNQPQ--APTAPVPHTHIQQAPA 805 Query: 669 PLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQK---L 725 L P + P H P L+ L P + + +GP GP+ + L Sbjct: 806 -LHPQR-PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL-HGQGPPGPHSLQAGPL 862 Query: 726 LY-----QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNL----EELPPAQ 776 L Q F +G SP+ + T + + + LPPA Sbjct: 863 LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922 Query: 777 ---------PTAPLPAEPAPSSDANDNELPSPEPEEL---------ICPQTTHQTAEPAE 818 PT P+P PAP + + L P P + + P ++ T P Sbjct: 923 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982 Query: 819 DNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPP 860 + + +P ++ +PS A+ P G Q P PPASHPP Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPP 1022 Score = 52.0 bits (123), Expect = 3e-06 Identities = 110/448 (24%), Positives = 146/448 (32%), Gaps = 55/448 (12%) Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449 P+ + N S S Q + P+++ S P + PT P VPP Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP 775 Query: 450 PIPGVGKQLP--PSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507 Q P P T P P + + +R P P PS P L P TG Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH---PS-PHPPLQPLTG 831 Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSP 567 S QP + Q PP P GP + AG P L G PQ Sbjct: 832 SAGQPSAPSHAQ-----PPLHGQGPPGPHSLQAG-------------PLLQHPGP-PQPF 872 Query: 568 RKGPQTVNSSSIYSMYLQQATPPKNYQ-PAAHSALNKSVKAVYGKPVLPSGSTSPSPLPF 626 PQ + A P + Q PA+ SAL +S + +P+ P+PL Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPREQPL------PPAPLAM 925 Query: 627 LHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRP--LSPTKLTPIVHSPLR 684 H TP PQ P+ K P + P+ S +LP P L P H P Sbjct: 926 PHIKPPPTTPIPQLPAPQAHKHPPH--LSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 983 Query: 685 YQSDADLEALRRKLANAPRP---LKKRSSITEPEGPGGPN------IQKLLYQRFNTLAG 735 + L + L ++P L + ++ P P Q Q G Sbjct: 984 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043 Query: 736 GMEGTPFYQPSPSQDFMGTLADVD--------NGNTNANGNLEELPPAQ-PTAPLPAEPA 786 TP PS S G +G + A G+ LP Q L Sbjct: 1044 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 1103 Query: 787 PSSDANDNELPSPEPEELICPQTTHQTA 814 P S PSPEP + P Q+A Sbjct: 1104 PESPPPPPRSPSPEPTVVDTPSHASQSA 1131 Score = 38.9 bits (89), Expect = 0.027 Identities = 62/230 (26%), Positives = 81/230 (35%), Gaps = 44/230 (19%) Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390 S Q+PL TS A +Q+P++ S P + Q L A A P Sbjct: 879 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM------------P 926 Query: 391 TLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVP-----FSALGPTEKPGIEIG 445 +K ++ + + A P + G ++ P P S+L P Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-- 984 Query: 446 KVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPA 505 PPP+ QL P PS PG T S +LP P A P PT L Sbjct: 985 --PPPL-----QLMPQSQPLPSSPAQPPGLTQSQ------NLPPPPASHP----PTGLHQ 1027 Query: 506 TGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP 555 PQP Q VP P PP PP P+ + P P T A P Sbjct: 1028 VA--PQP----PFAQHPFVPGGP--PPITPPTCPSTSTPPAGPGTSAQPP 1069 >gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] Length = 1295 Score = 68.6 bits (166), Expect = 3e-11 Identities = 120/528 (22%), Positives = 207/528 (39%), Gaps = 81/528 (15%) Query: 81 RHEDSPTENSEQGGRQTQEQRTQR----NVINVPGEKRTENGVGNPRVELTLSELQDMAA 136 R E TE G + + + +++NVPGE + E ++ A Sbjct: 313 RGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQE---NKSNSEAL 369 Query: 137 RQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAM 196 +QQQQ++ QQQ + H L Q++RR ++ E ++++ ++R E ++ KL++ Sbjct: 370 KQQQQLQQQQQRDPEAHIK-HLLHQRQRRIEEQKEERRRVEE-QQRREREQRKLQEKEQQ 427 Query: 197 RGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSY 256 R D L E ER A E++QE + L + S++L+ Sbjct: 428 RRLEDMQA-----LRREEERRQA---EREQEYKRKQLEEQRQSERLQR------------ 467 Query: 257 NGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRER 316 +L++ + L+ Q Q+Q + QQQ++LL + + ++ + Sbjct: 468 ----------QLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKP 517 Query: 317 LYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSA--------GSFPVLGDPIKPQ 368 + ++++ R SPL+ S + + GP +P A P + P++PQ Sbjct: 518 AWAREVE-ERTRMNKQQNSPLAKS-KPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVEPQ 575 Query: 369 SLSIASNAAH-----------GRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEG 417 S AH RS+S D L +S P A PS G Sbjct: 576 EGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASH-DPDPAIPAPTATPSARG 634 Query: 418 SV-KQGTVSSQPVPFSALGPTEKPGIEI---GKVPPPIPGVGKQLPPSYGTYPSPTPLGP 473 +V +Q + + P GP+ P + + PP +P Q S T + + G Sbjct: 635 AVIRQNSDPTSEGP----GPSPNPPAWVRPDNEAPPKVP----QRTSSIATALNTSGAGG 686 Query: 474 GSTSSLERRKEGSLPRPSAGLPSRQRPTLLPAT-GSTPQPGSSQQIQQRISVPP--SPTY 530 + R L R G + ++LPA+ G PQ GS ++ + +S P SP Sbjct: 687 SRPAQAVRASNPDLRRSDPGW--ERSDSVLPASHGHLPQAGSLERNRVGVSSKPDSSPVL 744 Query: 531 PPAGPPAFPAGDSKPELPLT-VAIRPFLADKGSRPQSPRKGPQTVNSS 577 P S+P P V ++ D+ RP P+K +SS Sbjct: 745 SPGNKAKPDDHRSRPGRPADFVLLKERTLDEAPRP--PKKAMDYSSSS 790 Score = 34.3 bits (77), Expect = 0.66 Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 9/117 (7%) Query: 60 HMMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGV 119 H++++ ++ ++EE + R E+ EQ R+ QE+ QR + ++ +R E Sbjct: 389 HLLHQRQRRIEEQKEERR---RVEEQQRREREQ--RKLQEKEQQRRLEDMQALRREEERR 443 Query: 120 GNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKL 176 R + E + +Q+Q E Q+ L + L L+QQ+++QQ + ++L Sbjct: 444 QAEREQ----EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQL 496 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 67.8 bits (164), Expect = 5e-11 Identities = 113/470 (24%), Positives = 154/470 (32%), Gaps = 88/470 (18%) Query: 308 KRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKP 367 +R++ LR L + +SS +P SG P I P F + P P Sbjct: 614 ERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSG------PQILTPLGDRFVIPPHPKVP 667 Query: 368 QSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQ 427 S P K S + P A A P S + S Sbjct: 668 APFSP-----------------PPSKPRSPNPAAPALAAPAVVPGPV---STTDASPQSP 707 Query: 428 PVPFSALGPT-EKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPL------GPGSTSSLE 480 P P + L P E P I + PPP P PPSY P PT P ++ + E Sbjct: 708 PTPQTTLTPLQESPVISKDQSPPPSP------PPSYHPPPPPTKKPEVVVEAPSASETAE 761 Query: 481 RR-KEGSLPRPSAGLPSRQR-----------------------PTLLPATGSTPQPGSSQ 516 ++ + P P P Q P+ P S+P SS Sbjct: 762 EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSS 821 Query: 517 QIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNS 576 +I P SP PPA P PA + + P KG P G V Sbjct: 822 ATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTP 881 Query: 577 SSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLP----------- 625 S + + L+ P A AL S + L SG SP P P Sbjct: 882 SLLQMVRLRSVGAPGG---APTPALGPSAPQKPLRRAL-SGRASPVPAPSSGLHAAVRLK 937 Query: 626 --FLHGSLSTGTPQPQPPSESTEKEPEQDGPAAP---ADGSTVESLPRPLSP---TKLTP 677 L S + QP P E+ + P+ A + GS L RP+SP L Sbjct: 938 ACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQR 997 Query: 678 IVHSPLRYQSDADLEALRRKLANAPRPLKKRSS--ITEPEGPGGPNIQKL 725 + + LR S+ +K AP P+ ++ S + P P P + L Sbjct: 998 NLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPL 1047 Score = 63.2 bits (152), Expect = 1e-09 Identities = 128/556 (23%), Positives = 193/556 (34%), Gaps = 86/556 (15%) Query: 352 VPSAGSFPVLGDPIKPQSLSIASNA---AHGRSKSANDGNWPTLKQNSSSSVKPVQVAGA 408 V S G F + P +P+S +S++ +H +S + TL S +P + Sbjct: 390 VRSLGRFSSVSSP-QPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTAS 448 Query: 409 DWKDPSVEGSVKQGTVS-------SQPVPFSALGPTEKPGIEIGKV--PPPIPGVGKQLP 459 + P +G +G+ S S + + G + + K+ PPP P + Sbjct: 449 NSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPP----RRT 504 Query: 460 PSYGTYPSPTPLGP-GSTSSLERRKEGSLPRP-----SAGLPSRQRPTLLPATGSTP--Q 511 S P GP G ER+++ LPRP S G + P PA P Sbjct: 505 HSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPN-PANSWVPGLS 563 Query: 512 PGSSQQ---IQQRISVPPS--------PTYPP---AGPPAFPAGDSKPELPLTVAIRP-- 555 PG S++ +R P S PT PP AGPPA P P+ ++R Sbjct: 564 PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPG 623 Query: 556 --------FLADKGSRPQ-SPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVK 606 L S P S R GPQ + + P + P + + Sbjct: 624 ASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPA 683 Query: 607 AVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESL 666 A P L + + P P+ S + +PQ PP+ T P Q+ P D S S Sbjct: 684 A----PALAAPAVVPGPV-----STTDASPQ-SPPTPQTTLTPLQESPVISKDQSPPPSP 733 Query: 667 PR----PLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNI 722 P P PTK +V A+ P P + ++ + P Sbjct: 734 PPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPP--- 790 Query: 723 QKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP-L 781 ++ + + G G+P SP+ A L+ PP P P Sbjct: 791 EEAFFSVASPEPAGPSGSPELVSSPAASSSSATA------------LQIQPPGSPDPPPA 838 Query: 782 PAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAP 841 P PAP+S A + P+ E + C + P ED + T + + AP Sbjct: 839 PPAPAPASSAPGHVAKLPQKEPVGC---SKGGGPPREDVGAPLVTPSLLQMVRLRSVGAP 895 Query: 842 --SPGEEQVPPAPLPP 855 +P P AP P Sbjct: 896 GGAPTPALGPSAPQKP 911 Score = 58.5 bits (140), Expect = 3e-08 Identities = 135/592 (22%), Positives = 202/592 (34%), Gaps = 96/592 (16%) Query: 327 VNGTSSPQSPLSTSGRVAAVGPYIQ--VPSAGSFPVLGDPIKPQSLSIASNAAHGRSK-- 382 + G + P PLS + ++ Y+ +P A VL + +L S R Sbjct: 328 LTGGAGPAEPLSPAMSISPQATYLSKLIPHA----VLPPTVDVVALGRCSLRTLSRCSLH 383 Query: 383 SANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTE-KPG 441 SA+ + +L + SS S + + S T+ S S+ G +E +P Sbjct: 384 SASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPE 443 Query: 442 IEIGK---VPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498 VPPP G G+ P T + + +L R G L S L + Sbjct: 444 SSTASNSVVPPPQGGSGRGSPSGGSTAEA--------SDTLSIRSSGQLSGRSVSLRKLK 495 Query: 499 RPTLLPATGSTPQPGSSQQIQQR-ISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIR--- 554 RP P P + + QR ++VP P G P P +P+LP Sbjct: 496 RPP--------PPPRRTHSLHQRGLAVPDGPL----GLPPKPERKQQPQLPRPPTTGGSE 543 Query: 555 ----------------PFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQAT-PPKNYQ-PA 596 P L+ GSR + PR +T++ SS YS T PPK P Sbjct: 544 GAGAAPCPPNPANSWVPGLSPGGSR-RPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP 602 Query: 597 AHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQ----PQPPSESTEKEPEQD 652 A + K + G++ S L L S S P PQ + ++ Sbjct: 603 ASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPP 662 Query: 653 GPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSIT 712 P PA S S PR SP P + +P A P P+ + Sbjct: 663 HPKVPAPFSPPPSKPR--SPNPAAPALAAP----------------AVVPGPVSTTDA-- 702 Query: 713 EPEGPGGPNIQKLLYQRFNTLAGGMEGTP-----FYQPSPSQDFMGTLADVDNGNTNANG 767 P+ P P Q ++ P ++ P P + + + + A Sbjct: 703 SPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETA-- 760 Query: 768 NLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATV 827 E P P P P PAP + + + P PEE + + A P+ + + + Sbjct: 761 ---EEPLQDPNWPPPPPPAPE-EQDLSMADFPPPEEAFFSVASPEPAGPS--GSPELVSS 814 Query: 828 PTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTG 879 P + + PG PPAP PA PA+S K P E G Sbjct: 815 PAASSSSATALQIQPPGSPDPPPAPPAPA---PASSAPGHV-AKLPQKEPVG 862 Score = 55.1 bits (131), Expect = 4e-07 Identities = 118/530 (22%), Positives = 174/530 (32%), Gaps = 91/530 (17%) Query: 411 KDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPS--- 467 + P+ GS G P P ++ P PG + PP P + L PS G Y S Sbjct: 535 RPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGS--RRPPRSPE--RTLSPSSG-YSSQSG 589 Query: 468 -PT---------PLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQ 517 PT P PG + + SL P A + S ++ P S Q Sbjct: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQ 649 Query: 518 IQ----QRISVPPSPTYP-PAGPPAFPAGDSKPELPLTVA---IRPFLADKGSRPQSPRK 569 I R +PP P P P PP P P A + ++ + PQSP Sbjct: 650 ILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPT 709 Query: 570 GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHG 629 T+ + + +PP + P+ H + K + T+ PL Sbjct: 710 PQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQ---- 765 Query: 630 SLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDA 689 P P PP+ + D P P + + P P P+ +V SP S A Sbjct: 766 --DPNWPPPPPPAPEEQDLSMADFPP-PEEAFFSVASPEPAGPSGSPELVSSPAASSSSA 822 Query: 690 DLEALR--------------RKLANAPR-----PLKKRSSITEPEGP-----GGPNIQKL 725 ++ ++AP P K+ ++ GP G P + Sbjct: 823 TALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPS 882 Query: 726 LYQRFNTLAGGMEG---TPFYQPSPSQD-----FMGTLADVDNGNTNANGNL-------- 769 L Q + G G TP PS Q G + V ++ + + Sbjct: 883 LLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLA 942 Query: 770 --EELPPAQPTAPLPAEPAP--SSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVA 825 E L AQP P AEP P S + + + S +L + + E D N+ Sbjct: 943 ASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPV--SPETQADLQRNL- 999 Query: 826 TVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNS 875 VAE S E++ P AP PP + + P S Sbjct: 1000 -----------VAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPAS 1038 Score = 43.1 bits (100), Expect = 0.001 Identities = 91/439 (20%), Positives = 146/439 (33%), Gaps = 74/439 (16%) Query: 495 PSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIR 554 P RP L G T G ++ + +S+ P TY P P + + R Sbjct: 315 PPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYL---SKLIPHAVLPPTVDVVALGR 371 Query: 555 PFLADKGSRPQSPRKGPQTVNS----SSIYSMYLQQATPPKNYQPAAHSALNKSV----- 605 L SR P +V S SS+ S + P + +HS + ++ Sbjct: 372 CSLRTL-SRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGS 430 Query: 606 --KAVYGKPVLPSGST-SPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGST 662 + G P ST S S +P G G+P +E+++ + + Sbjct: 431 TLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVS 490 Query: 663 VESLPRPLSPTKLTPIVHSPLRYQSDADL----EALRRKLANAPR--------------- 703 + L RP P + T +H D L + R++ PR Sbjct: 491 LRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPC 550 Query: 704 PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGG---MEGTPFYQPS-------------- 746 P +S PGG +R + + G GTP P Sbjct: 551 PPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQP 610 Query: 747 PSQDFMGTL----ADVDNGNTNANGNLEELPPAQPTAPL--------------PAEPAP- 787 P + + +L A V + T+ + + P+ + P P PAP Sbjct: 611 PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPF 670 Query: 788 SSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQ 847 S + P+P L P P + + + PT + +P+ E+P ++Q Sbjct: 671 SPPPSKPRSPNPAAPALAAPAV---VPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQ 727 Query: 848 VPPAPLPPASHPPATSTNK 866 PP PP+ HPP T K Sbjct: 728 SPPPSPPPSYHPPPPPTKK 746 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 67.0 bits (162), Expect = 9e-11 Identities = 87/386 (22%), Positives = 132/386 (34%), Gaps = 54/386 (13%) Query: 490 PSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPL 549 P+ + + + P STP+ +S + P PT P A P PE P Sbjct: 977 PATTVHAPEEPDTAAVRVSTPEEPASPAAA--VPTPEEPTSPAAAVPT-------PEEPT 1027 Query: 550 TVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVY 609 + A ++ + P + P+ S + ++ T P P + + A Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA--AAV 1085 Query: 610 GKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRP 669 P P+ + P P S + P P+ P+ P + PA+PA ++P P Sbjct: 1086 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPA-----AAVPTP 1140 Query: 670 LSPTKLTPIVHSPLRYQSDADL----EALRRKLANAPRPLKKRS------SITEPEGPGG 719 P P V +P S A E A P P + S ++ EP P Sbjct: 1141 EEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAA 1200 Query: 720 PNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTA 779 TP + ++F A V A+ P +PT+ Sbjct: 1201 S-----------------VPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTS 1243 Query: 780 PLPAEPAPSSDANDNELPSPEPEELICPQ----TTHQTAEPA------EDNNNNVATVPT 829 P A P + + PEEL P T + A PA E+ + A VPT Sbjct: 1244 PAAAVPT-LEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPT 1302 Query: 830 TEQIPSPVAEAPSPGEEQVPPAPLPP 855 E P A P+P +P A +PP Sbjct: 1303 PEVAAIPAASVPTPEVPAIPAAAVPP 1328 Score = 60.8 bits (146), Expect = 7e-09 Identities = 78/346 (22%), Positives = 119/346 (34%), Gaps = 41/346 (11%) Query: 532 PAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPK 591 P GP PE P T A+R ++ + P + P+ S + ++ T P Sbjct: 971 PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030 Query: 592 NYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQ 651 P + + A P P+ + P P S + P P+ P+ P Sbjct: 1031 AAVPPPEEPTSPA--AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088 Query: 652 DGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSI 711 + P +PA ++P P PT V +P S A + P +++ Sbjct: 1089 EEPTSPA-----AAVPTPEEPTSPAAAVPTPEEPASPA------AAVPTPEEPASPAAAV 1137 Query: 712 TEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSP---------SQDFMGTLADVDNGN 762 PE P P + + A + TP SP S F +A ++ Sbjct: 1138 PTPEEPAFPAPAVPTPEESASAAVAVP-TPEESASPAAAVPTPAESASFAAVVATLEEPT 1196 Query: 763 TNANG---------NLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQT 813 + A LEE + P EPA + A N PEE P T Sbjct: 1197 SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN------PEEPTSPAAAVPT 1250 Query: 814 AEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHP 859 E + ++ A V T E++ SP A P+P E P A + P Sbjct: 1251 LE---EPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP 1293 Score = 50.1 bits (118), Expect = 1e-05 Identities = 82/349 (23%), Positives = 115/349 (32%), Gaps = 57/349 (16%) Query: 520 QRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSI 579 +R +VP P G A A S E VA + +G + P+ + Sbjct: 905 ERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAA--ITQEGMSAVAGFS-PEWAALAIT 961 Query: 580 YSMYLQQATPPKNYQPAA--HSALNKSVKAV-YGKPVLPSGSTSPSPLPFLHGSLSTGTP 636 + + TP PA H+ AV P P+ + P P S + P Sbjct: 962 VPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP 1021 Query: 637 QPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRR 696 P+ P+ P + P +PA ++P P PT V +P S A Sbjct: 1022 TPEEPTSPAAAVPPPEEPTSPA-----AAVPTPEEPTSPAAAVPTPEEPTSPA------A 1070 Query: 697 KLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLA 756 + P +++ PE P P TP SP+ Sbjct: 1071 AVPTPEEPTSPAAAVPTPEEPTSP--------------AAAVPTPEEPTSPAA------- 1109 Query: 757 DVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEP 816 A EE PA P A +P P+S A P PEE P T E Sbjct: 1110 --------AVPTPEE--PASPAAAVPTPEEPASPA----AAVPTPEEPAFPAPAVPTPE- 1154 Query: 817 AEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHP--PATS 863 ++ + VPT E+ SP A P+P E A + P PA S Sbjct: 1155 --ESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAAS 1201 Score = 47.8 bits (112), Expect = 6e-05 Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 22/200 (11%) Query: 669 PLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQ 728 P P VH+P + D A+R ++ P +++ PE P P + Sbjct: 971 PEGPVTPATTVHAP----EEPDTAAVR--VSTPEEPASPAAAVPTPEEPTSPAAAVPTPE 1024 Query: 729 RFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPS 788 + A + P ++ A V + P +PT+P A P P Sbjct: 1025 EPTSPAAAVP--------PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1076 Query: 789 SDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQV 848 + P PEE P T E + + A VPT E+ SP A P+P E Sbjct: 1077 EPTSP-AAAVPTPEEPTSPAAAVPTPE---EPTSPAAAVPTPEEPASPAAAVPTPEEPAS 1132 Query: 849 P----PAPLPPASHPPATST 864 P P P PA PA T Sbjct: 1133 PAAAVPTPEEPAFPAPAVPT 1152 Score = 43.5 bits (101), Expect = 0.001 Identities = 60/259 (23%), Positives = 89/259 (34%), Gaps = 41/259 (15%) Query: 611 KPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSES----TEKEPEQDGPAAPADGSTVESL 666 K V +G+T P L P Q PS + T K+ +P +G+++ ++ Sbjct: 812 KQVTKAGNTEPV--------LEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAV 863 Query: 667 PRPLSPT---KLTPIVHSPLRYQSDADLEA--LRRKLANAP-RPLKKRSSITEPEGPGGP 720 P P L P H + S LE + +AP R +++ PEG Sbjct: 864 PAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAA- 922 Query: 721 NIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP 780 ++ E P + +Q+ M +A G E T P Sbjct: 923 ---------VAAVSSPEETAPAVAAAITQEGMSAVA----------GFSPEWAALAITVP 963 Query: 781 LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEA 840 + E PEE P T E+ + A VPT E+ SP A Sbjct: 964 ITEEDGTPEGPVTPATTVHAPEE---PDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020 Query: 841 PSPGEEQVPPAPLPPASHP 859 P+P E P A +PP P Sbjct: 1021 PTPEEPTSPAAAVPPPEEP 1039 >gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo sapiens] Length = 782 Score = 67.0 bits (162), Expect = 9e-11 Identities = 48/147 (32%), Positives = 72/147 (48%), Gaps = 19/147 (12%) Query: 884 VRFNPLALLLDASLEGEFDLVQRIIYEVE-------DPSKP----------NDEGITPLH 926 VRF A L A G+ D + ++ + DP+ P N +GI+ LH Sbjct: 47 VRFERAAEFLAACAGGDLDEARLMLRAADPGPGAELDPAAPPPARAVLDSTNADGISALH 106 Query: 927 NAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTIS 986 A + +V+FL++ G VN AD++GWTPLH AASC + + + L+ GA I A+ S Sbjct: 107 QACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANI-AAVNS 165 Query: 987 DIETAADKCE-EMEEGYIQCSQFLYGV 1012 D + D E + EG ++ GV Sbjct: 166 DGDLPLDLAESDAMEGLLKAEIARRGV 192 Score = 53.9 bits (128), Expect = 8e-07 Identities = 37/124 (29%), Positives = 59/124 (47%), Gaps = 20/124 (16%) Query: 840 APSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEG 899 A PG P A L PA+ PPA + TN + ++ L A ++ Sbjct: 73 AADPG----PGAELDPAAPPPARAVLDSTNA----------------DGISALHQACIDE 112 Query: 900 EFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLH 959 ++V+ ++ + ++ ++EG TPLH A G+ I ++LL G N+ A +SDG PL Sbjct: 113 NLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLD 172 Query: 960 CAAS 963 A S Sbjct: 173 LAES 176 Score = 48.5 bits (114), Expect = 3e-05 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 921 GITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAI 980 G + LH A G+ +++ LL G + D DGWTPLH AA C+ L E G + Sbjct: 227 GASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGM 286 Query: 981 FASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKL 1016 + T C+ +E + + L QE L Sbjct: 287 DSLT----HAGQRPCDLADEEVLSLLEELARKQEDL 318 >gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] Length = 1303 Score = 66.6 bits (161), Expect = 1e-10 Identities = 110/494 (22%), Positives = 195/494 (39%), Gaps = 81/494 (16%) Query: 81 RHEDSPTENSEQGGRQTQEQRTQR----NVINVPGEKRTENGVGNPRVELTLSELQDMAA 136 R E TE G + + + +++NVPGE + E ++ A Sbjct: 313 RGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQE---NKSNSEAL 369 Query: 137 RQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAM 196 +QQQQ++ QQQ + H L Q++RR ++ E ++++ ++R E ++ KL++ Sbjct: 370 KQQQQLQQQQQRDPEAHIK-HLLHQRQRRIEEQKEERRRVEE-QQRREREQRKLQEKEQQ 427 Query: 197 RGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSY 256 R D L E ER A E++QE + L + S++L+ Sbjct: 428 RRLEDMQA-----LRREEERRQA---EREQEYKRKQLEEQRQSERLQR------------ 467 Query: 257 NGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRER 316 +L++ + L+ Q Q+Q + QQQ++LL + + ++ + Sbjct: 468 ----------QLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKP 517 Query: 317 LYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSA--------GSFPVLGDPIKPQ 368 + ++++ R SPL+ S + + GP +P A P + P++PQ Sbjct: 518 AWAREVE-ERTRMNKQQNSPLAKS-KPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVEPQ 575 Query: 369 SLSIASNAAH-----------GRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEG 417 S AH RS+S D L +S P A PS G Sbjct: 576 EGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASH-DPDPAIPAPTATPSARG 634 Query: 418 SV-KQGTVSSQPVPFSALGPTEKPGIEI---GKVPPPIPGVGKQLPPSYGTYPSPTPLGP 473 +V +Q + + P GP+ P + + PP +P Q S T + + G Sbjct: 635 AVIRQNSDPTSEGP----GPSPNPPAWVRPDNEAPPKVP----QRTSSIATALNTSGAGG 686 Query: 474 GSTSSLERRKEGSLPRPSAGLPSRQRPTLLPAT-GSTPQPGSSQQIQQRISVPPSPTYPP 532 + R L R G + ++LPA+ G PQ GS ++ + +S + P Sbjct: 687 SRPAQAVRASNPDLRRSDPGW--ERSDSVLPASHGHLPQAGSLERNRVGVS-----SKPD 739 Query: 533 AGPPAFPAGDSKPE 546 + P P +KP+ Sbjct: 740 SSPVLSPGNKAKPD 753 Score = 34.3 bits (77), Expect = 0.66 Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 9/117 (7%) Query: 60 HMMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGV 119 H++++ ++ ++EE + R E+ EQ R+ QE+ QR + ++ +R E Sbjct: 389 HLLHQRQRRIEEQKEERR---RVEEQQRREREQ--RKLQEKEQQRRLEDMQALRREEERR 443 Query: 120 GNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKL 176 R + E + +Q+Q E Q+ L + L L+QQ+++QQ + ++L Sbjct: 444 QAEREQ----EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQL 496 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.129 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 50,940,677 Number of Sequences: 37866 Number of extensions: 3225763 Number of successful extensions: 37526 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 651 Number of HSP's successfully gapped in prelim test: 2147 Number of HSP's that attempted gapping in prelim test: 17858 Number of HSP's gapped (non-prelim): 14129 length of query: 1090 length of database: 18,247,518 effective HSP length: 113 effective length of query: 977 effective length of database: 13,968,660 effective search space: 13647380820 effective search space used: 13647380820 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.