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Search of human proteins with 120953264
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|120953264 folliculin interacting protein 1 isoform 2 [Homo
sapiens]
(1138 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|120953264 folliculin interacting protein 1 isoform 2 [Homo sa... 2297 0.0
gi|120953291 folliculin interacting protein 1 isoform 1 [Homo sa... 2282 0.0
gi|154689769 folliculin interacting protein 2 [Homo sapiens] 678 0.0
gi|209969819 hypothetical protein LOC253143 [Homo sapiens] 37 0.082
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 36 0.24
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 36 0.24
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 36 0.24
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 36 0.24
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 36 0.24
gi|13491168 pumilio homolog 2 [Homo sapiens] 35 0.41
gi|134152667 ICBP90 binding protein 1 [Homo sapiens] 34 0.69
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 33 1.5
gi|16445033 ACRC protein [Homo sapiens] 33 1.5
gi|38569484 kinesin family member 21A [Homo sapiens] 33 2.0
gi|150170670 piccolo isoform 2 [Homo sapiens] 33 2.0
gi|150378539 piccolo isoform 1 [Homo sapiens] 33 2.0
gi|31742492 Nedd4 binding protein 2 [Homo sapiens] 33 2.0
gi|88759339 aster-associated protein [Homo sapiens] 33 2.0
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 32 2.6
gi|206597470 neural precursor cell expressed, developmentally do... 32 3.4
gi|206597468 neural precursor cell expressed, developmentally do... 32 3.4
gi|23097254 neural precursor cell expressed, developmentally dow... 32 3.4
gi|206597465 neural precursor cell expressed, developmentally do... 32 3.4
gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens] 32 4.5
gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens] 32 4.5
gi|154426278 hypothetical protein LOC90523 [Homo sapiens] 32 4.5
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 31 5.9
gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13... 31 5.9
gi|189083849 delta-aminolevulinic acid dehydratase [Homo sapiens] 31 5.9
gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo sap... 31 7.6
>gi|120953264 folliculin interacting protein 1 isoform 2 [Homo
sapiens]
Length = 1138
Score = 2297 bits (5953), Expect = 0.0
Identities = 1138/1138 (100%), Positives = 1138/1138 (100%)
Query: 1 MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD 60
MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD
Sbjct: 1 MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD 60
Query: 61 SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS 120
SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS
Sbjct: 61 SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS 120
Query: 121 RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD 180
RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD
Sbjct: 121 RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD 180
Query: 181 SLEFINQDNNTLKADNNTVINGLLGNIVHSNPMDMPGRELNEDRDSGIARSASLSSLLIT 240
SLEFINQDNNTLKADNNTVINGLLGNIVHSNPMDMPGRELNEDRDSGIARSASLSSLLIT
Sbjct: 181 SLEFINQDNNTLKADNNTVINGLLGNIVHSNPMDMPGRELNEDRDSGIARSASLSSLLIT 240
Query: 241 PFPSPNSSLTRSCASSYQRRWRRSQTTSLENGVFPRWSIEESFNLSDESCGPNPGIVRKK 300
PFPSPNSSLTRSCASSYQRRWRRSQTTSLENGVFPRWSIEESFNLSDESCGPNPGIVRKK
Sbjct: 241 PFPSPNSSLTRSCASSYQRRWRRSQTTSLENGVFPRWSIEESFNLSDESCGPNPGIVRKK 300
Query: 301 KIAIGVIFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADASQRSL 360
KIAIGVIFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADASQRSL
Sbjct: 301 KIAIGVIFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADASQRSL 360
Query: 361 AYNRIVDALNEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNHLCYRFMKEFTFLMENASK 420
AYNRIVDALNEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNHLCYRFMKEFTFLMENASK
Sbjct: 361 AYNRIVDALNEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNHLCYRFMKEFTFLMENASK 420
Query: 421 NQFLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVDMLAKTHPYNPLWAQLGD 480
NQFLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVDMLAKTHPYNPLWAQLGD
Sbjct: 421 NQFLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVDMLAKTHPYNPLWAQLGD 480
Query: 481 LYGAIGSPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPGTV 540
LYGAIGSPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPGTV
Sbjct: 481 LYGAIGSPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPGTV 540
Query: 541 ITTTLEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCKYCSHPLLGQNVENISQQ 600
ITTTLEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCKYCSHPLLGQNVENISQQ
Sbjct: 541 ITTTLEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCKYCSHPLLGQNVENISQQ 600
Query: 601 EREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVCTGSVP 660
EREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVCTGSVP
Sbjct: 601 EREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVCTGSVP 660
Query: 661 VDKCALSESGLESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQ 720
VDKCALSESGLESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQ
Sbjct: 661 VDKCALSESGLESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQ 720
Query: 721 TKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGES 780
TKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGES
Sbjct: 721 TKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGES 780
Query: 781 DTQNMVSEEPCELPCWNHSDPESMSLFDEYFNDDSIETRTIDDVPFKTSTDSKDHCCMLE 840
DTQNMVSEEPCELPCWNHSDPESMSLFDEYFNDDSIETRTIDDVPFKTSTDSKDHCCMLE
Sbjct: 781 DTQNMVSEEPCELPCWNHSDPESMSLFDEYFNDDSIETRTIDDVPFKTSTDSKDHCCMLE 840
Query: 841 FSKILCTKNNKQNNEFCKCIETVPQDSCKTCFPQQDQRDTLSILVPHGDKESSDKKIAVG 900
FSKILCTKNNKQNNEFCKCIETVPQDSCKTCFPQQDQRDTLSILVPHGDKESSDKKIAVG
Sbjct: 841 FSKILCTKNNKQNNEFCKCIETVPQDSCKTCFPQQDQRDTLSILVPHGDKESSDKKIAVG 900
Query: 901 TEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAEEDEIPFPGSKLIEVSA 960
TEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAEEDEIPFPGSKLIEVSA
Sbjct: 901 TEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAEEDEIPFPGSKLIEVSA 960
Query: 961 VQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSDLSHAVQHPVLDEPIAEAV 1020
VQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSDLSHAVQHPVLDEPIAEAV
Sbjct: 961 VQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSDLSHAVQHPVLDEPIAEAV 1020
Query: 1021 CIIADMDKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHSTLQLYKHNLSPNFCVMHLE 1080
CIIADMDKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHSTLQLYKHNLSPNFCVMHLE
Sbjct: 1021 CIIADMDKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHSTLQLYKHNLSPNFCVMHLE 1080
Query: 1081 DRLQELYFKSKMLSEYLRGQMRVHVKELGVVLGIESSDLPLLAAVASTHSPYVAQILL 1138
DRLQELYFKSKMLSEYLRGQMRVHVKELGVVLGIESSDLPLLAAVASTHSPYVAQILL
Sbjct: 1081 DRLQELYFKSKMLSEYLRGQMRVHVKELGVVLGIESSDLPLLAAVASTHSPYVAQILL 1138
>gi|120953291 folliculin interacting protein 1 isoform 1 [Homo
sapiens]
Length = 1166
Score = 2282 bits (5914), Expect = 0.0
Identities = 1138/1166 (97%), Positives = 1138/1166 (97%), Gaps = 28/1166 (2%)
Query: 1 MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD 60
MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD
Sbjct: 1 MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD 60
Query: 61 SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS 120
SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS
Sbjct: 61 SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS 120
Query: 121 RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD 180
RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD
Sbjct: 121 RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD 180
Query: 181 SLEFINQDNNTLKADNNTVINGLLGNI----------------------------VHSNP 212
SLEFINQDNNTLKADNNTVINGLLGNI VHSNP
Sbjct: 181 SLEFINQDNNTLKADNNTVINGLLGNIGLSQFCSPRRAFSEQGPLRLIRSASFFAVHSNP 240
Query: 213 MDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENG 272
MDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENG
Sbjct: 241 MDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENG 300
Query: 273 VFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFE 332
VFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFE
Sbjct: 301 VFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFE 360
Query: 333 SHMNKLKSAIEQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLT 392
SHMNKLKSAIEQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLT
Sbjct: 361 SHMNKLKSAIEQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLT 420
Query: 393 MMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKI 452
MMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKI
Sbjct: 421 MMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKI 480
Query: 453 FLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLT 512
FLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLT
Sbjct: 481 FLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLT 540
Query: 513 YFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKES 572
YFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKES
Sbjct: 541 YFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKES 600
Query: 573 EEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENA 632
EEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENA
Sbjct: 601 EEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENA 660
Query: 633 VDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGK 692
VDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGK
Sbjct: 661 VDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGK 720
Query: 693 AMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHH 752
AMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHH
Sbjct: 721 AMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHH 780
Query: 753 TKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFN 812
TKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFN
Sbjct: 781 TKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFN 840
Query: 813 DDSIETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCF 872
DDSIETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCF
Sbjct: 841 DDSIETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCF 900
Query: 873 PQQDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVS 932
PQQDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVS
Sbjct: 901 PQQDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVS 960
Query: 933 SYYGGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSD 992
SYYGGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSD
Sbjct: 961 SYYGGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSD 1020
Query: 993 ERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVS 1052
ERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVS
Sbjct: 1021 ERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVS 1080
Query: 1053 SLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVL 1112
SLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVL
Sbjct: 1081 SLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVL 1140
Query: 1113 GIESSDLPLLAAVASTHSPYVAQILL 1138
GIESSDLPLLAAVASTHSPYVAQILL
Sbjct: 1141 GIESSDLPLLAAVASTHSPYVAQILL 1166
>gi|154689769 folliculin interacting protein 2 [Homo sapiens]
Length = 1114
Score = 678 bits (1750), Expect = 0.0
Identities = 401/764 (52%), Positives = 500/764 (65%), Gaps = 38/764 (4%)
Query: 1 MAPTLFQKLFSKRTGLG---APGRDARDPDCG--FSWPLPEFDPSQIRLIVYQDCERRGR 55
MAPTL QKLF+KR G A R P G FSW EFD ++IRLIVYQDC+RRGR
Sbjct: 1 MAPTLLQKLFNKRGSSGSSAAASAQGRAPKEGPAFSWSCSEFDLNEIRLIVYQDCDRRGR 60
Query: 56 NVLFDSSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSD-----I 110
VLFDS ++ E+++ K D +K+ KCCQ SSSS S SSS
Sbjct: 61 QVLFDSKAVQKIEEVTAQKT-EDVPIKISAKCCQGSSSVSSSSSSSISSHSSSGGSSHHA 119
Query: 111 KDQCLKYQGSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSS 170
K+Q KYQ +R +SD NMLGEMMFGSVAMSYKGSTLKIH IRSPPQLM+SKVF+AR GS
Sbjct: 120 KEQLPKYQYTRPASDVNMLGEMMFGSVAMSYKGSTLKIHYIRSPPQLMISKVFSARMGS- 178
Query: 171 ICGSLNTLQDSLEFINQDNNTLKADNNTVINGLL---GNIVHSNPMDMPGRELNEDRDSG 227
CGS N LQDS E+INQD N K + N G N+ HS P+DMP R NEDRDSG
Sbjct: 179 FCGSTNNLQDSFEYINQDPNLGKLNTNQNSLGPCRTGSNLAHSTPVDMPSRGQNEDRDSG 238
Query: 228 IARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENGVFPRWSIEESFNLSD 287
IARSASLSSLLITPFPSP+SS + S SSYQRRW RSQTTSLENG+ PR S +E+F+L++
Sbjct: 239 IARSASLSSLLITPFPSPSSSTSSS--SSYQRRWLRSQTTSLENGIIPRRSTDETFSLAE 296
Query: 288 ESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMK 347
E+C NP +VR+KKIAI +IFSL + E+ F +FFFSHFPLFESHMN+LKSAIE+AM
Sbjct: 297 ETCSSNPAMVRRKKIAISIIFSLCEKEEAQRNFQDFFFSHFPLFESHMNRLKSAIEKAMI 356
Query: 348 MSRRSADASQRSLAY-NRIVDALNEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNHLCYR 406
R+ A++S R Y +R+++AL EFR TI NLY++PRI EPVWLTMMSGT EKN LC R
Sbjct: 357 SCRKIAESSLRVQFYVSRLMEALGEFRGTIWNLYSVPRIAEPVWLTMMSGTLEKNQLCQR 416
Query: 407 FMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVDMLA 466
F+KEFT L+E +KNQF AL+TAVLT HLAWVPTVMP PPIK F EK +SQSV+MLA
Sbjct: 417 FLKEFTLLIEQINKNQFFAALLTAVLTYHLAWVPTVMPVDHPPIKAFSEKRTSQSVNMLA 476
Query: 467 KTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETHLL 526
KTHPYNPLWAQLGDLYGAIGSPVRL RTVVVGK++D+VQR+LY LTYF+RCSELQE L
Sbjct: 477 KTHPYNPLWAQLGDLYGAIGSPVRLTRTVVVGKQKDLVQRILYVLTYFLRCSELQENQLT 536
Query: 527 ENGE--DEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCKY 584
+G + V+ G+ I T LEKGE+EESEYV++T+ RN+ +L+ N
Sbjct: 537 WSGNHGEGDQVLNGSKIITALEKGEVEESEYVVITV-RNEPALVPPILPPTAAERHNPWP 595
Query: 585 CSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRT 644
P + ++ + D + + + G S+ C + + ++ +
Sbjct: 596 TGFPECPEGTDSRDLGLKPDKEANRRPEQG-SEACSAGCLGPASDAS------WKPQNAF 648
Query: 645 CFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKK 704
C D K + GS + C + +G++ ++ +LL + T RS V
Sbjct: 649 CGDEKNKEAPQDGSSRLPSCEVLGAGMKMDQQA--VCELLKVEMPTRLPDRS----VAWP 702
Query: 705 PPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQI 748
PD+ + S E KVTF IG SP+SD E R + + +++
Sbjct: 703 CPDRHLREKPSLE----KVTFQIGSFASPESDFESRMKKMEERV 742
Score = 313 bits (801), Expect = 8e-85
Identities = 167/255 (65%), Positives = 196/255 (76%), Gaps = 11/255 (4%)
Query: 885 VPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAE 944
+P GD +KK TE DIPRNESSDSALGDS+ E M + +GG++ +
Sbjct: 870 IPCGD---DNKKANFRTEGDIPRNESSDSALGDSDDEACASAM---LDLGHGGDRTGGSL 923
Query: 945 EDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSDLS 1004
E E+P P S+ I N+ NFGRSLL GYC +Y+PD VL G GSDE+ +QCL++DL
Sbjct: 924 EVELPLPRSQSISTQ----NVRNFGRSLLAGYCPTYMPDLVLHGTGSDEKLKQCLVADLV 979
Query: 1005 HAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDN-KLGKEVLVSSLVSNLLHSTL 1063
H V HPVLDEPIAEAVCIIAD DKW+VQVA+SQR+VTDN KLG++VLVSS VS+LL S L
Sbjct: 980 HTVHHPVLDEPIAEAVCIIADTDKWSVQVATSQRKVTDNMKLGQDVLVSSQVSSLLQSIL 1039
Query: 1064 QLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVLGIESSDLPLLA 1123
QLYK +L +FC+MHLEDRLQE+Y KSKMLSEYLRG RVHVKELGVVLGIES+DLPLL
Sbjct: 1040 QLYKLHLPADFCIMHLEDRLQEMYLKSKMLSEYLRGHTRVHVKELGVVLGIESNDLPLLT 1099
Query: 1124 AVASTHSPYVAQILL 1138
A+ASTHSPYVAQILL
Sbjct: 1100 AIASTHSPYVAQILL 1114
>gi|209969819 hypothetical protein LOC253143 [Homo sapiens]
Length = 2151
Score = 37.4 bits (85), Expect = 0.082
Identities = 93/461 (20%), Positives = 167/461 (36%), Gaps = 102/461 (22%)
Query: 487 SPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETHLLEN--GEDEAIVMPGTVITTT 544
S ++L+ + GK QD V + F Y I +QE + N G ++ + TV+ ++
Sbjct: 894 SSIKLSEEGLEGKEQD-VSKETVFCKYNISDHAIQELNQTVNIPGPEKVLDQSPTVMFSS 952
Query: 545 LEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCKYCSHPLLGQNV-ENISQQERE 603
+ + E T+ + +L +S + R C + GQ+ E +S +RE
Sbjct: 953 FKNVKSVE------TLDQKADEVLDCQSNQNRPDECKSE-------GQSAKEMLSSDQRE 999
Query: 604 -------DIQNSSKELL-----------GISDECQM----ISPSDCQE--ENAVDVKQYR 639
++ ++ K+LL G +C + + S C E E VD+ Y
Sbjct: 1000 TVTEPHGEVNHNQKDLLVSSGSNNSLPCGSPKKCNLKGAFVKMSGCDESTEGMVDIV-YT 1058
Query: 640 DKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQ--SEKLLDSDSHTGKAMRST 697
D C + E V+ + + C + L E++ S + LD+ +HTG + +
Sbjct: 1059 D----CSNKLAEGVLDVKASNLLDCGARQEKLAFQEDSRSTLSRRELDA-AHTGTTGQDS 1113
Query: 698 GMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLK 757
V + SCE + PDS ++V D +P K
Sbjct: 1114 DFPVTAASTVDFLKIKKSCEENVCRSLKDCEMEKCPDSCAH-EMESVADH------EPNK 1166
Query: 758 EERGAIDQHQETKQTTKDQSGES--DTQNMVSEEPCEL-------PCWNHSDPESMSLFD 808
G ++ + G S +TQ M E + S ESMS D
Sbjct: 1167 RILGRVNLSLNDSHYGQQDKGTSLRETQEMTEGSRLEPNSEFGKESTFGISSKESMSCHD 1226
Query: 809 EYFNDDSIETRTIDDVPFKTSTDSKD-----------HCCMLEFSKILCTK--------- 848
E S+ R++ + S ++ + + C + ++LC
Sbjct: 1227 E----SSVSLRSLKSIEIMPSQENSETNVNSEETDLKNLCKPKDGEMLCENVKDCTVLPE 1282
Query: 849 ----------NNKQNNEFCKCIETVPQDSCKTCFPQQDQRD 879
N+ + C C+E +++CK C P ++ D
Sbjct: 1283 MKEIVSRDWSNSSDRDSVCTCVE---KNACKACHPHENSSD 1320
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 35.8 bits (81), Expect = 0.24
Identities = 48/236 (20%), Positives = 85/236 (36%), Gaps = 22/236 (9%)
Query: 557 LVTMHRNKSSLLFKESEEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGIS 616
L+ H+ K+S +E ++ C+ + +S QE EDI+ S++E
Sbjct: 678 LLQQHKQKTSRKPREERDVS----QCESVA--------STVSAQEDEDIEASNEEENPED 725
Query: 617 DECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVCTG---SVPVDKCALSESGLES 673
E + + PS+ ENA + + ET T +VP K A ES
Sbjct: 726 SEVEAVKPSEDSPENATSRGNTEPAVE--LEPTTETAPSTSPSLAVPSTKPAEDESVETQ 783
Query: 674 TEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSP 733
++ +E D + G V + P K + + + GD+ +
Sbjct: 784 VNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDN-TK 842
Query: 734 DSDTELRSQAV----VDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQNM 785
+ D + S+ V D + + E + + T +D GE + Q M
Sbjct: 843 ERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPERQRM 898
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 35.8 bits (81), Expect = 0.24
Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 597 ISQQEREDIQNSSKELLGIS-DECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVC 655
+S + R + E+L +S DE + + + ++ DV + ++ L F KL+ VV
Sbjct: 798 VSDKHRMSFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLD--FVPKLDQVVE 855
Query: 656 TGSVPVDKCALSESGLESTEETWQSEKLLDSDS 688
+ ++P CA+ E+ + +EE Q+ K D DS
Sbjct: 856 SPAIPRIPCAMPETVVIRSEEQEQASKEYDEDS 888
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 35.8 bits (81), Expect = 0.24
Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 597 ISQQEREDIQNSSKELLGIS-DECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVC 655
+S + R + E+L +S DE + + + ++ DV + ++ L F KL+ VV
Sbjct: 798 VSDKHRMSFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLD--FVPKLDQVVE 855
Query: 656 TGSVPVDKCALSESGLESTEETWQSEKLLDSDS 688
+ ++P CA+ E+ + +EE Q+ K D DS
Sbjct: 856 SPAIPRIPCAMPETVVIRSEEQEQASKEYDEDS 888
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 35.8 bits (81), Expect = 0.24
Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 597 ISQQEREDIQNSSKELLGIS-DECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVC 655
+S + R + E+L +S DE + + + ++ DV + ++ L F KL+ VV
Sbjct: 798 VSDKHRMSFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLD--FVPKLDQVVE 855
Query: 656 TGSVPVDKCALSESGLESTEETWQSEKLLDSDS 688
+ ++P CA+ E+ + +EE Q+ K D DS
Sbjct: 856 SPAIPRIPCAMPETVVIRSEEQEQASKEYDEDS 888
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 35.8 bits (81), Expect = 0.24
Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
Query: 597 ISQQEREDIQNSSKELLGIS-DECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVC 655
+S + R + E+L +S DE + + + ++ DV + ++ L F KL+ VV
Sbjct: 798 VSDKHRMSFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLD--FVPKLDQVVE 855
Query: 656 TGSVPVDKCALSESGLESTEETWQSEKLLDSDS 688
+ ++P CA+ E+ + +EE Q+ K D DS
Sbjct: 856 SPAIPRIPCAMPETVVIRSEEQEQASKEYDEDS 888
>gi|13491168 pumilio homolog 2 [Homo sapiens]
Length = 1064
Score = 35.0 bits (79), Expect = 0.41
Identities = 35/126 (27%), Positives = 57/126 (45%), Gaps = 13/126 (10%)
Query: 664 CALSESGLESTEETWQSEKLLDSDSHTGKAMR-STGMVVEKKPPDKIVPAS--FSCEAAQ 720
C + + LES QSE + + D H K ++ G V +K + + P S F +A +
Sbjct: 813 CRVIQKALESISSDQQSEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFK 872
Query: 721 TKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGES 780
+V L S P + Q +++ T T P+ EE HQ T+Q +DQ G
Sbjct: 873 GQVFVL---STHPYGCRVI--QRILEHCTAEQTLPILEE-----LHQHTEQLVQDQYGNY 922
Query: 781 DTQNMV 786
Q+++
Sbjct: 923 VIQHVL 928
>gi|134152667 ICBP90 binding protein 1 [Homo sapiens]
Length = 1440
Score = 34.3 bits (77), Expect = 0.69
Identities = 28/126 (22%), Positives = 54/126 (42%), Gaps = 10/126 (7%)
Query: 671 LESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIV-------PASFSCEAAQTKV 723
L+ + Q + D++S TG +++ + P V P + ++A +
Sbjct: 841 LKEVLQRLQEQLTKDTESMTGSPLQNQTACIGVLFPSAEVALLMHPAPGAVDADSAGSDS 900
Query: 724 TFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQ 783
T L+ +SP D EL+S A DQ K L+E + ++Q+ Q +GE
Sbjct: 901 TSLVDSELSPSEDRELKSDASSDQGPASPEKVLEE---SSIENQDVSQERPHSNGELQDS 957
Query: 784 NMVSEE 789
++++
Sbjct: 958 GPLAQQ 963
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 33.1 bits (74), Expect = 1.5
Identities = 37/155 (23%), Positives = 67/155 (43%), Gaps = 15/155 (9%)
Query: 662 DKCALSESGLESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQT 721
DK ++ L+ + +++KL + TG +K P + V + + +AAQ
Sbjct: 1814 DKILATKKNLDHVNKILKAKKL-QRQARTGNNFVKRRPGRPRKCPLQAVVSMQAFQAAQF 1872
Query: 722 KVTFLIGDS------MSPDSDTELRSQAVVDQITRH--HTKPLKEERGAIDQHQETKQTT 773
L D +SPD+ T++ +AVV + + H K LK + +++ KQ
Sbjct: 1873 VNPELNRDEEGAALHLSPDTVTDV-IEAVVQSVNLNPEHKKGLKRKGWLLEEQTRKKQKP 1931
Query: 774 KDQSGESDTQNMVSEEPCELPCWNH-----SDPES 803
+ E + +E P E+P + S+PES
Sbjct: 1932 LPEEEEQENNKSFNEAPVEIPSPSETPAKPSEPES 1966
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 33.1 bits (74), Expect = 1.5
Identities = 59/263 (22%), Positives = 98/263 (37%), Gaps = 16/263 (6%)
Query: 764 DQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFNDDSIETRTIDD 823
D + + + D S +S+ + S++ E P N D E+ D+ +D + DD
Sbjct: 140 DDNSDDSEAPDDNSDDSEAPDDNSDDS-EAPDDNSDDSEAP---DDNSDDSDVPDDNSDD 195
Query: 824 VPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIET-VPQDSCKTCFPQQDQRDTLS 882
S DS D + S + K++ + ++ VP DS D D
Sbjct: 196 SSDDNSDDSSDDNS--DDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSE 253
Query: 883 ILVPHGDK-----ESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTR--QVSSYY 935
D +SSD A D +E+SD + DSE+ D D + S
Sbjct: 254 APDDSSDDSEAPDDSSDDSEAPDDSSD--DSEASDDSSDDSEASDDSSDDSEAPDDKSDD 311
Query: 936 GGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERF 995
ED +++ ++P S +EV ++ N G+ V Q SD+
Sbjct: 312 SDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAG 371
Query: 996 RQCLMSDLSHAVQHPVLDEPIAE 1018
Q L +LS P + ++E
Sbjct: 372 EQDLGENLSKPPSDPEANPEVSE 394
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 32.7 bits (73), Expect = 2.0
Identities = 31/163 (19%), Positives = 67/163 (41%), Gaps = 8/163 (4%)
Query: 890 KESSDKKIAVGTE--WDIPRNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAEEDE 947
KE KK G E D + + + + + E+ + + +++VS + E+E+ EED+
Sbjct: 551 KEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDD 610
Query: 948 IPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSDLSH-- 1005
I G E + AN+ L C + ++ + + ++ Q L
Sbjct: 611 ID-GGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKL 669
Query: 1006 -AVQHPVLDEPIA--EAVCIIADMDKWTVQVASSQRRVTDNKL 1045
+QH + D + + + + ++ ++ + A R + KL
Sbjct: 670 MMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKL 712
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 32.7 bits (73), Expect = 2.0
Identities = 87/439 (19%), Positives = 165/439 (37%), Gaps = 96/439 (21%)
Query: 589 LLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFDA 648
L+ + + + + + I KE L + M++ QEE+ ++ +DK +
Sbjct: 1156 LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE----KDKA-SALQE 1210
Query: 649 KLETVVCTGSVPVDKCALSESG---LESTEETWQSEKLLDS------DSHTGKAMRSTGM 699
K +P ++ SE LE + T + +KLL + ++S
Sbjct: 1211 KKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQ 1270
Query: 700 VVEKKPPDKIVPASFS-CEAAQTKVTFL-IGDSMSPDSDTELRSQAVVDQITRHHTKPLK 757
+ E+K ++ P + + QTK+ L G S + + ++ + +Q P
Sbjct: 1271 IAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ-------PQP 1323
Query: 758 EERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFNDDSIE 817
DQ + K+ T+ + +SDT + S++P P+ +S D ++ D I
Sbjct: 1324 PCTAKPDQVEPGKEKTEKEDDKSDTSS--SQQP--------KSPQGLS--DTGYSSDGIS 1371
Query: 818 TRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETV-------------- 863
+ ++ ++P TD KD L+ + ++ K TV
Sbjct: 1372 S-SLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430
Query: 864 ---------------PQDSCKTCFPQQDQRDTLSILVPHGD-KESSDKK---IAVGTEWD 904
P+D KT Q +TL I + + KES +++ ++ D
Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKT----QSLSETLEITISEEEIKESQEERKDTFKKDSQQD 1486
Query: 905 IP-----------------RNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAEED- 946
IP R E DS SESE++ ++ +S +++ +ED
Sbjct: 1487 IPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDS 1546
Query: 947 -----EIPFPGSKLIEVSA 960
E F ++IE+SA
Sbjct: 1547 QGSGEEEDFIRKQIIEMSA 1565
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 32.7 bits (73), Expect = 2.0
Identities = 87/439 (19%), Positives = 165/439 (37%), Gaps = 96/439 (21%)
Query: 589 LLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFDA 648
L+ + + + + + I KE L + M++ QEE+ ++ +DK +
Sbjct: 1156 LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE----KDKA-SALQE 1210
Query: 649 KLETVVCTGSVPVDKCALSESG---LESTEETWQSEKLLDS------DSHTGKAMRSTGM 699
K +P ++ SE LE + T + +KLL + ++S
Sbjct: 1211 KKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQ 1270
Query: 700 VVEKKPPDKIVPASFS-CEAAQTKVTFL-IGDSMSPDSDTELRSQAVVDQITRHHTKPLK 757
+ E+K ++ P + + QTK+ L G S + + ++ + +Q P
Sbjct: 1271 IAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ-------PQP 1323
Query: 758 EERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFNDDSIE 817
DQ + K+ T+ + +SDT + S++P P+ +S D ++ D I
Sbjct: 1324 PCTAKPDQVEPGKEKTEKEDDKSDTSS--SQQP--------KSPQGLS--DTGYSSDGIS 1371
Query: 818 TRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETV-------------- 863
+ ++ ++P TD KD L+ + ++ K TV
Sbjct: 1372 S-SLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430
Query: 864 ---------------PQDSCKTCFPQQDQRDTLSILVPHGD-KESSDKK---IAVGTEWD 904
P+D KT Q +TL I + + KES +++ ++ D
Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKT----QSLSETLEITISEEEIKESQEERKDTFKKDSQQD 1486
Query: 905 IP-----------------RNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAEED- 946
IP R E DS SESE++ ++ +S +++ +ED
Sbjct: 1487 IPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDS 1546
Query: 947 -----EIPFPGSKLIEVSA 960
E F ++IE+SA
Sbjct: 1547 QGSGEEEDFIRKQIIEMSA 1565
>gi|31742492 Nedd4 binding protein 2 [Homo sapiens]
Length = 1770
Score = 32.7 bits (73), Expect = 2.0
Identities = 71/388 (18%), Positives = 137/388 (35%), Gaps = 37/388 (9%)
Query: 465 LAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETH 524
L++ H Y L+ + + P LAR + G ++ + R+L F+ + +
Sbjct: 529 LSQKHKYKVLFREPDTWWKF--KPKELARRNIHGVSKEKITRMLEHYQRFVSVPIIMSSS 586
Query: 525 LLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCKY 584
+ E E + +T + + E ++ N SL K E T N
Sbjct: 587 VPEKIERIELCAYSCEDRSTSPR----DDEDIISEKEENILSLSLKHLEF--TEEKNLDV 640
Query: 585 CSHPLLGQNVENISQQE----REDIQNSSKEL----------LGISDECQMISPSDCQEE 630
+L +NV +S + R++I + + + + SD + +D E
Sbjct: 641 TKETMLPENVAYLSNADLNKRRKEISDMNPSIQSALILETPHMYFSDSESKLQATDKSEN 700
Query: 631 NAVDVKQYRDKLRTCFDAKLETV---VCTGSVPVDKCALSESGLESTEETWQSEKLLDSD 687
+++ + +T D+ +E V C + C L+ SG E++ E + +
Sbjct: 701 EQIEMVAVKGYSKTDTDSSMERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERA 760
Query: 688 SHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQ 747
+ T KA G K +K S V IG + TE S D+
Sbjct: 761 TVTKKAF---GKQKSKSTLEKFPRHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDK 817
Query: 748 ITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLF 807
+ +++ ++ + +S E ++ C + S+P + +
Sbjct: 818 KYNYPQSHKLVNSVSVNTDCVQQRGSPHESVEDGRKSQ---------CDDASEPLNSYKY 868
Query: 808 DEYFNDDSIETRTIDDVPFKTSTDSKDH 835
D Y N D + D P S ++H
Sbjct: 869 DAYKNIDKNSFNIMGDWPSSDSLAQREH 896
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 32.7 bits (73), Expect = 2.0
Identities = 38/180 (21%), Positives = 72/180 (40%), Gaps = 17/180 (9%)
Query: 668 ESGLESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSC--EAAQTKVTF 725
+ GLE E E L S + + EKK + + SC A + +
Sbjct: 191 KDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQ 250
Query: 726 LIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEER-----------GAIDQHQETKQTTK 774
++GDS SP S+ + ++IT +H +E A+++ +E++ T
Sbjct: 251 ILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTAD 310
Query: 775 DQSGESDTQNMVSEEPCEL-PCWNHSDPESMSLFDEYFNDDSIETRTIDDVPFKTSTDSK 833
D E ++ ++ + P + S +S + +IE R I + K ST+++
Sbjct: 311 DLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKN---KKSTNNR 367
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 32.3 bits (72), Expect = 2.6
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 20/86 (23%)
Query: 734 DSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCEL 793
DSDT+ S+ ++ RH ++P+++ R + + K + D+ ES+ + SE
Sbjct: 1138 DSDTDFCSR----RLRRHPSRPMRQSRRLRRKTPKKKYSDDDEEEESEENSRDSE----- 1188
Query: 794 PCWNHSDPESMSLFDEYFNDDSIETR 819
S F + F+DD +ETR
Sbjct: 1189 -----------SDFSDDFSDDFVETR 1203
>gi|206597470 neural precursor cell expressed, developmentally
down-regulated 1 isoform c [Homo sapiens]
Length = 571
Score = 32.0 bits (71), Expect = 3.4
Identities = 53/220 (24%), Positives = 92/220 (41%), Gaps = 35/220 (15%)
Query: 180 DSLEFINQDNNTLKADNNTVINGLLGNIVHSNPMDM----PGRELNEDRDSGIARSASLS 235
D +F+ Q N+ N V + +++HS+P+++ PG+E NE+RD +A
Sbjct: 342 DGFDFLPQLNSVFPPRKNPVTSST--SVLHSSPLNVFMGSPGKEENENRD----LTAESK 395
Query: 236 SLLITPFPSPNS-----SLTRSCASSYQRRWRRS--QTTSLENGVFPRWSIEESFNLS-- 286
+ + S +S L S A S S QT + E P IE
Sbjct: 396 KIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPP 455
Query: 287 -DESCGPNPGIVRKKKIAIGVIFSLSK---DEDENNKFNEFFFSHFPLFESHMNKLKSAI 342
+ S PNP I + GV SLS+ D NN+ N PL + +++ I
Sbjct: 456 INGSSTPNPKIA--SSVTAGVASSLSEKIADSIGNNRQNA------PLTSIQIRFIQNMI 507
Query: 343 EQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTM 382
++ + R +A R + N V+ + +F + ++++
Sbjct: 508 QETLDDFR---EACHRDIV-NLQVEMIKQFHMQLNEMHSL 543
>gi|206597468 neural precursor cell expressed, developmentally
down-regulated 1 isoform b [Homo sapiens]
Length = 660
Score = 32.0 bits (71), Expect = 3.4
Identities = 53/220 (24%), Positives = 92/220 (41%), Gaps = 35/220 (15%)
Query: 180 DSLEFINQDNNTLKADNNTVINGLLGNIVHSNPMDM----PGRELNEDRDSGIARSASLS 235
D +F+ Q N+ N V + +++HS+P+++ PG+E NE+RD +A
Sbjct: 431 DGFDFLPQLNSVFPPRKNPVTSST--SVLHSSPLNVFMGSPGKEENENRD----LTAESK 484
Query: 236 SLLITPFPSPNS-----SLTRSCASSYQRRWRRS--QTTSLENGVFPRWSIEESFNLS-- 286
+ + S +S L S A S S QT + E P IE
Sbjct: 485 KIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPP 544
Query: 287 -DESCGPNPGIVRKKKIAIGVIFSLSK---DEDENNKFNEFFFSHFPLFESHMNKLKSAI 342
+ S PNP I + GV SLS+ D NN+ N PL + +++ I
Sbjct: 545 INGSSTPNPKIA--SSVTAGVASSLSEKIADSIGNNRQNA------PLTSIQIRFIQNMI 596
Query: 343 EQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTM 382
++ + R +A R + N V+ + +F + ++++
Sbjct: 597 QETLDDFR---EACHRDIV-NLQVEMIKQFHMQLNEMHSL 632
>gi|23097254 neural precursor cell expressed, developmentally
down-regulated 1 isoform b [Homo sapiens]
Length = 660
Score = 32.0 bits (71), Expect = 3.4
Identities = 53/220 (24%), Positives = 92/220 (41%), Gaps = 35/220 (15%)
Query: 180 DSLEFINQDNNTLKADNNTVINGLLGNIVHSNPMDM----PGRELNEDRDSGIARSASLS 235
D +F+ Q N+ N V + +++HS+P+++ PG+E NE+RD +A
Sbjct: 431 DGFDFLPQLNSVFPPRKNPVTSST--SVLHSSPLNVFMGSPGKEENENRD----LTAESK 484
Query: 236 SLLITPFPSPNS-----SLTRSCASSYQRRWRRS--QTTSLENGVFPRWSIEESFNLS-- 286
+ + S +S L S A S S QT + E P IE
Sbjct: 485 KIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPP 544
Query: 287 -DESCGPNPGIVRKKKIAIGVIFSLSK---DEDENNKFNEFFFSHFPLFESHMNKLKSAI 342
+ S PNP I + GV SLS+ D NN+ N PL + +++ I
Sbjct: 545 INGSSTPNPKIA--SSVTAGVASSLSEKIADSIGNNRQNA------PLTSIQIRFIQNMI 596
Query: 343 EQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTM 382
++ + R +A R + N V+ + +F + ++++
Sbjct: 597 QETLDDFR---EACHRDIV-NLQVEMIKQFHMQLNEMHSL 632
>gi|206597465 neural precursor cell expressed, developmentally
down-regulated 1 isoform a [Homo sapiens]
Length = 667
Score = 32.0 bits (71), Expect = 3.4
Identities = 53/220 (24%), Positives = 92/220 (41%), Gaps = 35/220 (15%)
Query: 180 DSLEFINQDNNTLKADNNTVINGLLGNIVHSNPMDM----PGRELNEDRDSGIARSASLS 235
D +F+ Q N+ N V + +++HS+P+++ PG+E NE+RD +A
Sbjct: 438 DGFDFLPQLNSVFPPRKNPVTSST--SVLHSSPLNVFMGSPGKEENENRD----LTAESK 491
Query: 236 SLLITPFPSPNS-----SLTRSCASSYQRRWRRS--QTTSLENGVFPRWSIEESFNLS-- 286
+ + S +S L S A S S QT + E P IE
Sbjct: 492 KIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPP 551
Query: 287 -DESCGPNPGIVRKKKIAIGVIFSLSK---DEDENNKFNEFFFSHFPLFESHMNKLKSAI 342
+ S PNP I + GV SLS+ D NN+ N PL + +++ I
Sbjct: 552 INGSSTPNPKIA--SSVTAGVASSLSEKIADSIGNNRQNA------PLTSIQIRFIQNMI 603
Query: 343 EQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTM 382
++ + R +A R + N V+ + +F + ++++
Sbjct: 604 QETLDDFR---EACHRDIV-NLQVEMIKQFHMQLNEMHSL 639
>gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]
Length = 1251
Score = 31.6 bits (70), Expect = 4.5
Identities = 33/118 (27%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 591 GQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFD-AK 649
G N E E N + + D+ ++ S + E+ A R LR D A
Sbjct: 367 GHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQQAAQ----RTALRALSDSAV 422
Query: 650 LETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHT-GKAMRSTGMVVEKKPP 706
++ C SVP K + S S S+ + SE SDS T + S G KPP
Sbjct: 423 VQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEG----SKPP 476
>gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]
Length = 1226
Score = 31.6 bits (70), Expect = 4.5
Identities = 33/118 (27%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 591 GQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFD-AK 649
G N E E N + + D+ ++ S + E+ A R LR D A
Sbjct: 342 GHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQQAAQ----RTALRALSDSAV 397
Query: 650 LETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHT-GKAMRSTGMVVEKKPP 706
++ C SVP K + S S S+ + SE SDS T + S G KPP
Sbjct: 398 VQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEG----SKPP 451
>gi|154426278 hypothetical protein LOC90523 [Homo sapiens]
Length = 458
Score = 31.6 bits (70), Expect = 4.5
Identities = 36/142 (25%), Positives = 54/142 (38%), Gaps = 4/142 (2%)
Query: 816 IETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCFPQQ 875
+E + +D+ P KT + SKD+ + +Q E C I+ V QDS
Sbjct: 225 LEQKALDE-PAKTESVSKDNTLEPPVELYFPAQLRQQTEELCATIDKVLQDSLSMHSSDS 283
Query: 876 DQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYY 935
R ++L K + A G E S S + +S+ G V S
Sbjct: 284 PSRSPKTLLGSDTVKTPTTLPRAAGRETKYANLSSPSSTVSESQLTKPGVIRPVPVKSRI 343
Query: 936 GGEQEDWAEEDEIPFPGSKLIE 957
++E EE P P SK +E
Sbjct: 344 LLKKE---EEVYEPNPFSKYLE 362
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 31.2 bits (69), Expect = 5.9
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 12/76 (15%)
Query: 590 LGQNVENISQQEREDIQN--SSKELLGI-----SDECQMISPS--DCQEENAVDVKQYRD 640
L + EN+ Q+++E I N S +E++ I + IS +++ A DV + +
Sbjct: 462 LKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQ 521
Query: 641 KLRTCF---DAKLETV 653
KLRT F DA LETV
Sbjct: 522 KLRTAFTEKDALLETV 537
>gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13
[Homo sapiens]
Length = 5058
Score = 31.2 bits (69), Expect = 5.9
Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 7/110 (6%)
Query: 831 DSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTC----FPQQDQRDTLSILVP 886
D KD C+ KI + +++ + T+P+D+ K C F D+ L
Sbjct: 4084 DLKDMACVTSLIKIYIPQAFLKDSSGSELTYTIPKDTDKACLKGLFQALDENLHQLHLTG 4143
Query: 887 HGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYYG 936
+G +++ +++ + D N+ S ALG +ESE H T +S Y G
Sbjct: 4144 YGISDTTLEEVFLMLLQD--SNKKSHIALG-TESELQNHRPTGHLSGYCG 4190
>gi|189083849 delta-aminolevulinic acid dehydratase [Homo sapiens]
Length = 330
Score = 31.2 bits (69), Expect = 5.9
Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 16/83 (19%)
Query: 580 CNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDE-CQMISPSDCQE--------- 629
C C Y SH G EN + + E Q ++ L + CQ+++PSD +
Sbjct: 122 CLCPYTSHGHCGLLSENGAFRAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKEA 181
Query: 630 ------ENAVDVKQYRDKLRTCF 646
N V V Y K +CF
Sbjct: 182 LMAHGLGNRVSVMSYSAKFASCF 204
>gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo
sapiens]
Length = 497
Score = 30.8 bits (68), Expect = 7.6
Identities = 80/382 (20%), Positives = 143/382 (37%), Gaps = 38/382 (9%)
Query: 523 THLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNC-- 580
T + E E +V P ++ L+ ++ Y + +LF + I T
Sbjct: 22 TSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTM-------KEVLFYLGQYIMTKRLYD 74
Query: 581 ----NCKYCSHPLLGQ--NVENISQQEREDIQNSSKELLGI------SDECQMISPSDCQ 628
+ YCS+ LLG V + S +E I L + SD +S + C
Sbjct: 75 EKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCH 134
Query: 629 EENAVDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSE-KLLDSD 687
E D K +L+ + +V S + A+SE+ S E + + + K SD
Sbjct: 135 LEGGSDQKDLVQELQEEKPSSSH-LVSRPSTSSRRRAISETEENSDELSGERQRKRHKSD 193
Query: 688 SHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQ 747
S + S + V + + S S E+ T + +S S L +V DQ
Sbjct: 194 SISLSFDESLALCVIR---EICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQ 250
Query: 748 IT-RHHTKPLKEERGAI--------DQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNH 798
+ + L E ++ D+ E Q T Q+GESDT + EE E+ ++
Sbjct: 251 FSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSF--EEDPEISLADY 308
Query: 799 SDPESMSLFDEYFNDDSIETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCK 858
S + + + + + KD + E +K+ + ++ +
Sbjct: 309 WKCTSCNEMNPPLPSHCNRCWALRE-NWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPD 367
Query: 859 CIETVPQDSCKTCFPQQDQRDT 880
C +T+ DS ++C + D + T
Sbjct: 368 CKKTIVNDSRESCVEENDDKIT 389
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,140,232
Number of Sequences: 37866
Number of extensions: 2011141
Number of successful extensions: 5937
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 5884
Number of HSP's gapped (non-prelim): 97
length of query: 1138
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1025
effective length of database: 13,968,660
effective search space: 14317876500
effective search space used: 14317876500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.