Search of human proteins with 120953251

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|120953251 neuron navigator 3 [Homo sapiens]
         (2363 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|120953251 neuron navigator 3 [Homo sapiens]                       4646   0.0  
gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]             2435   0.0  
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]              2429   0.0  
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]             2408   0.0  
gi|161169017 neuron navigator 2 isoform 4 [Homo sapiens]             1720   0.0  
gi|169218146 PREDICTED: similar to neuron navigator 3, partial [...  1467   0.0  
gi|27262622 neuron navigator 1 [Homo sapiens]                        1264   0.0  
gi|239750047 PREDICTED: similar to neuron navigator 2, partial [...   701   0.0  
gi|239747580 PREDICTED: similar to NAV1 protein [Homo sapiens]        516   e-145
gi|16975496 cortactin binding protein 2 [Homo sapiens]                115   7e-25
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...   106   3e-22
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]           104   1e-21
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]           104   1e-21
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]           104   1e-21
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]           104   1e-21
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]           104   1e-21
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]           104   1e-21
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]           104   1e-21
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]           104   1e-21
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]           104   1e-21
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    99   6e-20
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        97   1e-19
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    94   1e-18
gi|91982772 mucin 17 [Homo sapiens]                                    92   6e-18
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        92   8e-18
gi|161016767 mucin 21 [Homo sapiens]                                   79   4e-14
gi|167736355 mucin 4 isoform a [Homo sapiens]                          77   2e-13
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        77   2e-13
gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]           77   2e-13
gi|83367077 mucin 16 [Homo sapiens]                                    75   6e-13

>gi|120953251 neuron navigator 3 [Homo sapiens]
          Length = 2363

 Score = 4646 bits (12050), Expect = 0.0
 Identities = 2363/2363 (100%), Positives = 2363/2363 (100%)

Query: 1    MPVLGVASKLRQPAVGSKPVHTALPIPNLGTTGSQHCSSRPLELTETESSMLSCQLALKS 60
            MPVLGVASKLRQPAVGSKPVHTALPIPNLGTTGSQHCSSRPLELTETESSMLSCQLALKS
Sbjct: 1    MPVLGVASKLRQPAVGSKPVHTALPIPNLGTTGSQHCSSRPLELTETESSMLSCQLALKS 60

Query: 61   TCEFGEKKPLQGKAKEKEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQII 120
            TCEFGEKKPLQGKAKEKEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQII
Sbjct: 61   TCEFGEKKPLQGKAKEKEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQII 120

Query: 121  ANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLS 180
            ANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLS
Sbjct: 121  ANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLS 180

Query: 181  RYKQQQHHQQQYYQSLVELQQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIAT 240
            RYKQQQHHQQQYYQSLVELQQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIAT
Sbjct: 181  RYKQQQHHQQQYYQSLVELQQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIAT 240

Query: 241  SQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQ 300
            SQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQ
Sbjct: 241  SQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQ 300

Query: 301  SSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPT 360
            SSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPT
Sbjct: 301  SSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPT 360

Query: 361  PSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSES 420
            PSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSES
Sbjct: 361  PSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSES 420

Query: 421  GEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCT 480
            GEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCT
Sbjct: 421  GEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCT 480

Query: 481  EKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQT 540
            EKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQT
Sbjct: 481  EKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQT 540

Query: 541  ISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMT 600
            ISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMT
Sbjct: 541  ISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMT 600

Query: 601  VAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDL 660
            VAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDL
Sbjct: 601  VAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDL 660

Query: 661  SYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDST 720
            SYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDST
Sbjct: 661  SYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDST 720

Query: 721  VTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFM 780
            VTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFM
Sbjct: 721  VTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFM 780

Query: 781  YTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGY 840
            YTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGY
Sbjct: 781  YTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGY 840

Query: 841  MTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTD 900
            MTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTD
Sbjct: 841  MTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTD 900

Query: 901  DLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGK 960
            DLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGK
Sbjct: 901  DLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGK 960

Query: 961  WKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAK 1020
            WKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAK
Sbjct: 961  WKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAK 1020

Query: 1021 ASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMIT 1080
            ASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMIT
Sbjct: 1021 ASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMIT 1080

Query: 1081 SSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPR 1140
            SSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPR
Sbjct: 1081 SSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPR 1140

Query: 1141 PSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKE 1200
            PSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKE
Sbjct: 1141 PSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKE 1200

Query: 1201 KEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKS 1260
            KEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKS
Sbjct: 1201 KEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKS 1260

Query: 1261 ASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTT 1320
            ASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTT
Sbjct: 1261 ASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTT 1320

Query: 1321 DVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPL 1380
            DVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPL
Sbjct: 1321 DVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPL 1380

Query: 1381 SHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEG 1440
            SHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEG
Sbjct: 1381 SHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEG 1440

Query: 1441 KEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSN 1500
            KEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSN
Sbjct: 1441 KEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSN 1500

Query: 1501 SIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYS 1560
            SIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYS
Sbjct: 1501 SIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYS 1560

Query: 1561 TAEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTA 1620
            TAEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTA
Sbjct: 1561 TAEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTA 1620

Query: 1621 EQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSAT 1680
            EQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSAT
Sbjct: 1621 EQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSAT 1680

Query: 1681 SHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSL 1740
            SHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSL
Sbjct: 1681 SHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSL 1740

Query: 1741 PASPKLPHNAGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEAL 1800
            PASPKLPHNAGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEAL
Sbjct: 1741 PASPKLPHNAGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEAL 1800

Query: 1801 SSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSL 1860
            SSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSL
Sbjct: 1801 SSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSL 1860

Query: 1861 GLSLNNLNITEAVSSDILLDDAGDATGHKDGRSVKIIVSISKGYGRAKDQKSQAYLIGSI 1920
            GLSLNNLNITEAVSSDILLDDAGDATGHKDGRSVKIIVSISKGYGRAKDQKSQAYLIGSI
Sbjct: 1861 GLSLNNLNITEAVSSDILLDDAGDATGHKDGRSVKIIVSISKGYGRAKDQKSQAYLIGSI 1920

Query: 1921 GVSGKTKWDVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLP 1980
            GVSGKTKWDVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLP
Sbjct: 1921 GVSGKTKWDVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLP 1980

Query: 1981 CGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGK 2040
            CGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGK
Sbjct: 1981 CGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGK 2040

Query: 2041 TYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVV 2100
            TYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVV
Sbjct: 2041 TYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVV 2100

Query: 2101 IILDNLHHVGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTE 2160
            IILDNLHHVGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTE
Sbjct: 2101 IILDNLHHVGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTE 2160

Query: 2161 PVKGFLGRYLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRL 2220
            PVKGFLGRYLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRL
Sbjct: 2161 PVKGFLGRYLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRL 2220

Query: 2221 FLPCPMDVEGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDTYPWSSA 2280
            FLPCPMDVEGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDTYPWSSA
Sbjct: 2221 FLPCPMDVEGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDTYPWSSA 2280

Query: 2281 TLPQESPALLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSST 2340
            TLPQESPALLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSST
Sbjct: 2281 TLPQESPALLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSST 2340

Query: 2341 QSCDSESTSHHEDILDSSLESTL 2363
            QSCDSESTSHHEDILDSSLESTL
Sbjct: 2341 QSCDSESTSHHEDILDSSLESTL 2363


>gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]
          Length = 2432

 Score = 2435 bits (6312), Expect = 0.0
 Identities = 1376/2477 (55%), Positives = 1742/2477 (70%), Gaps = 159/2477 (6%)

Query: 1    MPVLGVASKLRQPAVGSKPVHTALPIPNL--GTTGSQHCSSRPLELTETESSMLSCQLAL 58
            MP + VASK++      KPVH+A PI ++     G Q C  +     E   +    Q+ L
Sbjct: 1    MPAILVASKMKSGL--PKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPL 58

Query: 59   KSTCEFGEKKPL--------QGKAKEKEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADG 110
            KS    G ++P          G  +   D++IYTDWANHYLAKSGHKRLI+DLQQD+ DG
Sbjct: 59   KSQVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDG 118

Query: 111  VLLAEIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLK 170
            VLLA+IIQ++ANEK+EDINGCP+++SQMIEN+D CL+FLAA+G+N+QGLSAEEIRNGNLK
Sbjct: 119  VLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLK 178

Query: 171  AILGLFFSLSRYKQQQHHQQQYYQS--LVELQQRVTHASPPSEASQAKTQQDMQSSLAAR 228
            AILGLFFSLSRYKQQQ   Q+ + S  L     +V  A    +A   + Q  +      +
Sbjct: 179  AILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQ 238

Query: 229  YATQSNHSGIATSQKKPTRLPGPS-RVPAAGSSSKVQGASNL--NRRSQSFNSIDKNKP- 284
                + H       +  +RLPGP+ RV AAGS +K +G S    NRRSQSFN+ DK+KP 
Sbjct: 239  PHQPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPV 298

Query: 285  ---PNYANGNEKDSSKGPQSSS-GVNGNVQPPSTAGQPP-------ASAIPSP-SASKPW 332
               P   + +EK+      SS  G++ N      +G          +SAIP P +A+KPW
Sbjct: 299  TSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATKPW 358

Query: 333  RSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVN 392
            RSKS++VKHSAT +ML+VK       P P + R   P  E +K AP+ QKSMLEK KL N
Sbjct: 359  RSKSLSVKHSATVSMLSVKP------PGPEAPR---PTPEAMKPAPNNQKSMLEKLKLFN 409

Query: 393  ARTALRPPQPPSSGPSDGGKDDD--AFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPK 450
            ++   +  + P S  +   + +   +F ES E+E  +  L + G  +SSPK++ K    +
Sbjct: 410  SKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQR 469

Query: 451  AGSKNLSNKKSLLQPKEKE------EKNRDKNK-------VCTEKPVKEEKDQ------V 491
              S+ L+NKKS L+  EKE      EK+++K+K       V     +KEE  +      V
Sbjct: 470  TFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAV 529

Query: 492  TEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKES 551
             EM PKK+SKIAS IPKG K  +AKKE + PS SGIPKPG K    K   +P    SKE 
Sbjct: 530  PEM-PKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAP--SKEG 586

Query: 552  EKFRTTKGSPSQSLSKP-ITMEKASASSCPAPLEGREAGQASPSGSCT-MTVAQSSG--Q 607
            E+ R+ K S      KP +    +S+SS  A  EG+  G  + + S +  TV+ S G  Q
Sbjct: 587  ERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQ 646

Query: 608  STGNG--AVQLPQ-QQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLS-YS 663
            +TG+   +VQLPQ QQQ++HPNTATVAPF+YR+ ++ EG    +A+S ++   ++ S ++
Sbjct: 647  TTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNV--TAESSSTGVSVEPSHFT 704

Query: 664  KTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTT 723
            KT +  LEE++GEDPE RR+RTVKNIADLRQNLEETMSSLRGTQ++HSTLETTFD+ VTT
Sbjct: 705  KTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTT 764

Query: 724  EVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYP-RSGTSRFIHTDPSRFMYT 782
            E++GR+I +LT RPTP++WRLGQ+ PRLQAGDAPS+G GYP R+  SRFI+T+  R++Y+
Sbjct: 765  EMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYS 824

Query: 783  TPLRRAAVSRLGNMSQIDMSEKASSDLDMSS-EVDVGGYMSDGDILGKSLRTDDINSGYM 841
             PLRR   SR  ++  +D+S+KA  ++D+    +D  GYMSDGD+L K++RTDDI SGYM
Sbjct: 825  APLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYM 884

Query: 842  TDGGLNLYTRSLNRIPD-TATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTD 900
            TDGGL LYTR LNR+PD  A  R+ +QR       DADSWDDSSSVSSG+SDT+DN+STD
Sbjct: 885  TDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTD 944

Query: 901  DLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDET--WDSPEELKKPEEDFDS--HGD 956
            D+NT+SS+SSY+N    SRKN  ++TD+EK S  +    W S +++KK +   DS    +
Sbjct: 945  DINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLW-SGDDVKKSDGGSDSGIKME 1003

Query: 957  AGGKWKTVSSGLPEDPEKAGQ-KASLSVSQTGSWRRGMSAQGGAP---SRQKAGTSALKT 1012
             G KW+   S + ++ +K+   K +  +SQTGSWRRGM+AQ G     ++  A   ALKT
Sbjct: 1004 PGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKT 1063

Query: 1013 PG--KTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKP-PSGIGRSTATS-SFGFK 1068
            PG  KTDDAK SEKG+   K S ++RSPSDAG+SSGDE KKP PS     TA + SFGFK
Sbjct: 1064 PGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFK 1123

Query: 1069 KPSGVGSS-AMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHV 1127
            K SG  +  AMIT+SG T+TS SATLGKIPKS+A+  +S AGRK+S+DG+QNQDD  L +
Sbjct: 1124 KQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS-AGRKSSMDGAQNQDDGYLAL 1182

Query: 1128 SSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSG 1187
            SS+T LQYRSLPRPSKS++       G+RSSTSSIDSN+SSKSAG    KLREP+K   G
Sbjct: 1183 SSRTNLQYRSLPRPSKSNSRN---GAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALG 1239

Query: 1188 RSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACG-AQGLRQPGSKYPDIASP 1246
             S P  VNQTDKEK     SD+ESV+   S K +P +      AQ   QPG+KYPD+ASP
Sbjct: 1240 SSLPGLVNQTDKEKG--ISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASP 1297

Query: 1247 TFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSG 1306
            T RRLFG K   K       E +K+S V+ +P  T+ +QG+L+SPS G+G + S     G
Sbjct: 1298 TLRRLFGGKPT-KQVPIATAENMKNSVVISNPHATMTQQGNLDSPS-GSGVLSS-----G 1350

Query: 1307 SSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSM 1366
            SSSPL++K  DL          LASSP+S HS  S  L W  N SSSSA SKD   +QS+
Sbjct: 1351 SSSPLYSKNVDLNQS------PLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSV 1404

Query: 1367 TSLHTSSESIDLPLSH-----HGSLSGLTTGTHEVQ-SLLMRTGSVRSTLSESM------ 1414
            +SLHTS ESID+ LS      H S +GL   + +   +  +RT SV++TLSES       
Sbjct: 1405 SSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAA 1464

Query: 1415 -----------------QLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGN 1457
                              LDRNTLPKKGLRYTP+S+   QE+ KEWLRSHS GGLQDT  
Sbjct: 1465 SPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAA 1524

Query: 1458 QSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQL 1517
             SP  S S+++S +  +++FS L SPT ++Q +L  P+M+R++S+   D  +D Y DS+ 
Sbjct: 1525 NSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRF 1584

Query: 1518 CGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRE 1577
              S+ SL+E+ R +S SGSFRD  EEVHGSSLSLVSSTSS+YST EEK  SE I KLRRE
Sbjct: 1585 RNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSE-IRKLRRE 1643

Query: 1578 LVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEML 1637
            L ASQEKV+ LT+QL+ANAHLVAAFE+SLGNMT RLQSLTMTAEQK+SEL ELR+TIE+L
Sbjct: 1644 LDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELL 1703

Query: 1638 KAQNSAAQAAIQGALNGPDHPPK--------DLRIRRQHSSESVSSINSATSHSSIGSGN 1689
            K QN+AAQAAI G +N P+   K        DLRIRRQHSS+SVSSINSATSHSS+GS  
Sbjct: 1704 KKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNI 1763

Query: 1690 DADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHN 1749
            ++DSKKKK+KNWVN    ELRSSFKQAFGKKKS K  SSHSDIEE+TDSSLP+SPKLPHN
Sbjct: 1764 ESDSKKKKRKNWVN----ELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHN 1819

Query: 1750 AGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQI 1809
                 +  ++ S S S I EC ++EAE ++QL++ELR+KE+KLTDIRLEALSSAH LDQ+
Sbjct: 1820 GSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQL 1879

Query: 1810 REAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNNLNI 1869
            REAMNRMQ+EIE LKAENDRLK+E+  +   +R PS+ S S   +S RQS+GLS ++LN+
Sbjct: 1880 REAMNRMQSEIEKLKAENDRLKSESQGSGC-SRAPSQVSIS---ASPRQSMGLSQHSLNL 1935

Query: 1870 TEAVSSDILLDDAGDATGHKDG-RSVKIIVSISKGYGRAKDQKSQAYLIGSIGVSGKTKW 1928
            TE+ S D+LLDD G+ +  K+G R VKI+VS  +     +D +   +LIG IGVSGKTKW
Sbjct: 1936 TESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKW 1995

Query: 1929 DVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLPCGYLVGDN 1988
            DVLDGV+RRLFKEY+  +D  + LGL+SD +  Y IG++ RS+  E PELLPCGYLVG+N
Sbjct: 1996 DVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGEN 2055

Query: 1989 NIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGKTYLANKLA 2048
              I+V +KG+ ENSLDS VF++LIPKPI QRY +LL+EH RIILSGPSGTGKTYLAN+L+
Sbjct: 2056 TTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLS 2115

Query: 2049 EYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVVIILDNLHH 2108
            EY++ + GR+ T+  IATFNVDHKSSKEL+QYL+NLA+QC+++NN V++P+VIILDNLHH
Sbjct: 2116 EYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHH 2175

Query: 2109 VGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGR 2168
            V SL +IFNG LNCKY+KCPYIIGTMNQ  SS+PNL+LHHNFRWVLCANHTEPVKGFLGR
Sbjct: 2176 VSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGR 2235

Query: 2169 YLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDV 2228
            +LRRKL+E EI   +RN +LVKIIDWIPK WHHLN FLE HSSSDVTIGPRLFL CP+DV
Sbjct: 2236 FLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDV 2295

Query: 2229 EGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDTYPWSSATLPQESPA 2288
            +GSRVWF DLWNYS++PY+LEAVREGLQ+YG+R PWEDP+KWV+DTYPW+++    E P 
Sbjct: 2296 DGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPP 2355

Query: 2289 LLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSSTQSCDSE-- 2346
            LLQLRPEDVG++  +  +E +TSK +P +D EGDPLMNMLM+LQEAANYSS QS DS+  
Sbjct: 2356 LLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSN 2415

Query: 2347 STSHHEDILDSSLESTL 2363
            S SHH+DILDSSLESTL
Sbjct: 2416 SNSHHDDILDSSLESTL 2432


>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
          Length = 2429

 Score = 2429 bits (6294), Expect = 0.0
 Identities = 1373/2477 (55%), Positives = 1739/2477 (70%), Gaps = 162/2477 (6%)

Query: 1    MPVLGVASKLRQPAVGSKPVHTALPIPNL--GTTGSQHCSSRPLELTETESSMLSCQLAL 58
            MP + VASK++      KPVH+A PI ++     G Q C  +     E   +    Q+ L
Sbjct: 1    MPAILVASKMKSGL--PKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPL 58

Query: 59   KSTCEFGEKKPL--------QGKAKEKEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADG 110
            KS    G ++P          G  +   D++IYTDWANHYLAKSGHKRLI+DLQQD+ DG
Sbjct: 59   KSQVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDG 118

Query: 111  VLLAEIIQIIANEKVEDINGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLK 170
            VLLA+IIQ++ANEK+EDINGCP+++SQMIEN+D CL+FLAA+G+N+QGLSAEEIRNGNLK
Sbjct: 119  VLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLK 178

Query: 171  AILGLFFSLSRYKQQQHHQQQYYQS--LVELQQRVTHASPPSEASQAKTQQDMQSSLAAR 228
            AILGLFFSLSRYKQQQ   Q+ + S  L     +V  A    +A   + Q  +      +
Sbjct: 179  AILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQ 238

Query: 229  YATQSNHSGIATSQKKPTRLPGPS-RVPAAGSSSKVQGASNL--NRRSQSFNSIDKNKP- 284
                + H       +  +RLPGP+ RV AAGS +K +G S    NRRSQSFN+ DK+KP 
Sbjct: 239  PHQPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPV 298

Query: 285  ---PNYANGNEKDSSKGPQSSS-GVNGNVQPPSTAGQPP-------ASAIPSP-SASKPW 332
               P   + +EK+      SS  G++ N      +G          +SAIP P +A+KPW
Sbjct: 299  TSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATKPW 358

Query: 333  RSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVN 392
            RSKS++VKHSAT +ML+VK       P P + R   P  E +K AP+ QKSMLEK KL N
Sbjct: 359  RSKSLSVKHSATVSMLSVKP------PGPEAPR---PTPEAMKPAPNNQKSMLEKLKLFN 409

Query: 393  ARTALRPPQPPSSGPSDGGKDDD--AFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPK 450
            ++   +  + P S  +   + +   +F ES E+E  +  L + G  +SSPK++ K    +
Sbjct: 410  SKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQR 469

Query: 451  AGSKNLSNKKSLLQPKEKE------EKNRDKNK-------VCTEKPVKEEKDQ------V 491
              S+ L+NKKS L+  EKE      EK+++K+K       V     +KEE  +      V
Sbjct: 470  TFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAV 529

Query: 492  TEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKES 551
             EM PKK+SKIAS IPKG K  +AKKE + PS SGIPKPG K    K   +P    SKE 
Sbjct: 530  PEM-PKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAP--SKEG 586

Query: 552  EKFRTTKGSPSQSLSKP-ITMEKASASSCPAPLEGREAGQASPSGSCT-MTVAQSSG--Q 607
            E+ R+ K S      KP +    +S+SS  A  EG+  G  + + S +  TV+ S G  Q
Sbjct: 587  ERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQ 646

Query: 608  STGNG--AVQLPQ-QQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLS-YS 663
            +TG+   +VQLPQ QQQ++HPNTATVAPF+YR+ ++ EG    +A+S ++   ++ S ++
Sbjct: 647  TTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNV--TAESSSTGVSVEPSHFT 704

Query: 664  KTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTT 723
            KT +  LEE++GEDPE RR+RTVKNIADLRQNLEETMSSLRGTQ++HSTLETTFD+ VTT
Sbjct: 705  KTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTT 764

Query: 724  EVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYP-RSGTSRFIHTDPSRFMYT 782
            E++GR+I +LT RPTP++WRLGQ+ PRLQAGDAPS+G GYP R+  SRFI+T+  R++Y+
Sbjct: 765  EMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYS 824

Query: 783  TPLRRAAVSRLGNMSQIDMSEKASSDLDMSS-EVDVGGYMSDGDILGKSLRTDDINSGYM 841
             PLRR   SR  ++  +D+S+KA  ++D+    +D  GYMSDGD+L K++RTDDI SGYM
Sbjct: 825  APLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYM 884

Query: 842  TDGGLNLYTRSLNRIPD-TATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTD 900
            TDGGL LYTR LNR+PD  A  R+ +QR       DADSWDDSSSVSSG+SDT+DN+STD
Sbjct: 885  TDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTD 944

Query: 901  DLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDET--WDSPEELKKPEEDFDS--HGD 956
            D+NT+SS+SSY+N    SRKN  ++TD+EK S  +    W S +++KK +   DS    +
Sbjct: 945  DINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLW-SGDDVKKSDGGSDSGIKME 1003

Query: 957  AGGKWKTVSSGLPEDPEKAGQ-KASLSVSQTGSWRRGMSAQGGAP---SRQKAGTSALKT 1012
             G KW+   S + ++ +K+   K +  +SQTGSWRRGM+AQ G     ++  A   ALKT
Sbjct: 1004 PGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKT 1063

Query: 1013 PG--KTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKP-PSGIGRSTATS-SFGFK 1068
            PG  KTDDAK SEKG+   K S ++RSPSDAG+SSGDE KKP PS     TA + SFGFK
Sbjct: 1064 PGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFK 1123

Query: 1069 KPSGVGSS-AMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHV 1127
            K SG  +  AMIT+SG T+TS SATLGKIPKS+A+  +S AGRK+S+DG+QNQDD  L +
Sbjct: 1124 KQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS-AGRKSSMDGAQNQDDGYLAL 1182

Query: 1128 SSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSG 1187
            SS+T LQYRSLPRPSKS++       G+RSSTSSIDSN+SSKSAG    KLREP+K   G
Sbjct: 1183 SSRTNLQYRSLPRPSKSNSRN---GAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALG 1239

Query: 1188 RSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACG-AQGLRQPGSKYPDIASP 1246
             S P  VNQTDKEK     SD+ESV+   S K +P +      AQ   QPG+KYPD+ASP
Sbjct: 1240 SSLPGLVNQTDKEKG--ISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASP 1297

Query: 1247 TFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSG 1306
            T RRLFG K   K       E +K+S V+ +P  T+ +QG+L+SPS G+G + S     G
Sbjct: 1298 TLRRLFGGKPT-KQVPIATAENMKNSVVISNPHATMTQQGNLDSPS-GSGVLSS-----G 1350

Query: 1307 SSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSM 1366
            SSSPL++K  DL          LASSP+S HS  S  L W  N SSSSA SKD   +QS+
Sbjct: 1351 SSSPLYSKNVDLNQS------PLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSV 1404

Query: 1367 TSLHTSSESIDLPLSH-----HGSLSGLTTGTHEVQ-SLLMRTGSVRSTLSESM------ 1414
            +SLHTS ESID+ LS      H S +GL   + +   +  +RT SV++TLSES       
Sbjct: 1405 SSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAA 1464

Query: 1415 -----------------QLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGN 1457
                              LDRNTLPKKGLRYTP+S+   QE+ KEWLRSHS GGLQDT  
Sbjct: 1465 SPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAA 1524

Query: 1458 QSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQL 1517
             SP  S S+++S +  +++FS L SPT ++Q +L  P+M+R++S+   D  +D Y DS+ 
Sbjct: 1525 NSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRF 1584

Query: 1518 CGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRE 1577
              S+ SL+E+ R +S SGSFRD  EEVHGSSLSLVSSTSS+YST EEK  SE I KLRRE
Sbjct: 1585 RNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSE-IRKLRRE 1643

Query: 1578 LVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEML 1637
            L ASQEKV+ LT+QL+ANAHLVAAFE+SLGNMT RLQSLTMTAEQK+SEL ELR+TIE+L
Sbjct: 1644 LDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELL 1703

Query: 1638 KAQNSAAQAAIQGALNGPDHPPK--------DLRIRRQHSSESVSSINSATSHSSIGSGN 1689
            K QN+AAQAAI G +N P+   K        DLRIRRQHSS+SVSSINSATSHSS+GS  
Sbjct: 1704 KKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNI 1763

Query: 1690 DADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHN 1749
            ++DSKKKK+KNW       LRSSFKQAFGKKKS K  SSHSDIEE+TDSSLP+SPKLPHN
Sbjct: 1764 ESDSKKKKRKNW-------LRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHN 1816

Query: 1750 AGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQI 1809
                 +  ++ S S S I EC ++EAE ++QL++ELR+KE+KLTDIRLEALSSAH LDQ+
Sbjct: 1817 GSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQL 1876

Query: 1810 REAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNNLNI 1869
            REAMNRMQ+EIE LKAENDRLK+E+  +   +R PS+ S S   +S RQS+GLS ++LN+
Sbjct: 1877 REAMNRMQSEIEKLKAENDRLKSESQGSGC-SRAPSQVSIS---ASPRQSMGLSQHSLNL 1932

Query: 1870 TEAVSSDILLDDAGDATGHKDG-RSVKIIVSISKGYGRAKDQKSQAYLIGSIGVSGKTKW 1928
            TE+ S D+LLDD G+ +  K+G R VKI+VS  +     +D +   +LIG IGVSGKTKW
Sbjct: 1933 TESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKW 1992

Query: 1929 DVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLPCGYLVGDN 1988
            DVLDGV+RRLFKEY+  +D  + LGL+SD +  Y IG++ RS+  E PELLPCGYLVG+N
Sbjct: 1993 DVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGEN 2052

Query: 1989 NIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGKTYLANKLA 2048
              I+V +KG+ ENSLDS VF++LIPKPI QRY +LL+EH RIILSGPSGTGKTYLAN+L+
Sbjct: 2053 TTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLS 2112

Query: 2049 EYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVVIILDNLHH 2108
            EY++ + GR+ T+  IATFNVDHKSSKEL+QYL+NLA+QC+++NN V++P+VIILDNLHH
Sbjct: 2113 EYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHH 2172

Query: 2109 VGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGR 2168
            V SL +IFNG LNCKY+KCPYIIGTMNQ  SS+PNL+LHHNFRWVLCANHTEPVKGFLGR
Sbjct: 2173 VSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGR 2232

Query: 2169 YLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDV 2228
            +LRRKL+E EI   +RN +LVKIIDWIPK WHHLN FLE HSSSDVTIGPRLFL CP+DV
Sbjct: 2233 FLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDV 2292

Query: 2229 EGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDTYPWSSATLPQESPA 2288
            +GSRVWF DLWNYS++PY+LEAVREGLQ+YG+R PWEDP+KWV+DTYPW+++    E P 
Sbjct: 2293 DGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPP 2352

Query: 2289 LLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSSTQSCDSE-- 2346
            LLQLRPEDVG++  +  +E +TSK +P +D EGDPLMNMLM+LQEAANYSS QS DS+  
Sbjct: 2353 LLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSN 2412

Query: 2347 STSHHEDILDSSLESTL 2363
            S SHH+DILDSSLESTL
Sbjct: 2413 SNSHHDDILDSSLESTL 2429


>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
          Length = 2365

 Score = 2408 bits (6240), Expect = 0.0
 Identities = 1348/2391 (56%), Positives = 1703/2391 (71%), Gaps = 150/2391 (6%)

Query: 77   KEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEKVEDINGCPRSQS 136
            ++  +IYTDWANHYLAKSGHKRLI+DLQQD+ DGVLLA+IIQ++ANEK+EDINGCP+++S
Sbjct: 21   EDQKRIYTDWANHYLAKSGHKRLIRDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRS 80

Query: 137  QMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHHQQQYYQS- 195
            QMIEN+D CL+FLAA+G+N+QGLSAEEIRNGNLKAILGLFFSLSRYKQQQ   Q+ + S 
Sbjct: 81   QMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQPQKQHLSS 140

Query: 196  -LVELQQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPS-R 253
             L     +V  A    +A   + Q  +      +    + H       +  +RLPGP+ R
Sbjct: 141  PLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQAEMQSRLPGPTAR 200

Query: 254  VPAAGSSSKVQGASNL--NRRSQSFNSIDKNKP----PNYANGNEKDSSKGPQSSS-GVN 306
            V AAGS +K +G S    NRRSQSFN+ DK+KP    P   + +EK+      SS  G++
Sbjct: 201  VSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMS 260

Query: 307  GNVQPPSTAGQPP-------ASAIPSP-SASKPWRSKSMNVKHSATSTMLTVKQSSTATS 358
             N      +G          +SAIP P +A+KPWRSKS++VKHSAT +ML+VK       
Sbjct: 261  DNAPASLESGSSSTPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKP------ 314

Query: 359  PTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDD--A 416
            P P + R   P  E +K AP+ QKSMLEK KL N++   +  + P S  +   + +   +
Sbjct: 315  PGPEAPR---PTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPS 371

Query: 417  FSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKE------E 470
            F ES E+E  +  L + G  +SSPK++ K    +  S+ L+NKKS L+  EKE      E
Sbjct: 372  FEESEELEAASRMLTTVGPASSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQRE 431

Query: 471  KNRDKNK-------VCTEKPVKEEKDQ------VTEMAPKKTSKIASLIPKGSKTTAAKK 517
            K+++K+K       V     +KEE  +      V EM PKK+SKIAS IPKG K  +AKK
Sbjct: 432  KDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEM-PKKSSKIASFIPKGGKLNSAKK 490

Query: 518  ESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKP-ITMEKASA 576
            E + PS SGIPKPG K    K   +P    SKE E+ R+ K S      KP +    +S+
Sbjct: 491  EPMAPSHSGIPKPGMKSMPGKSPSAPAP--SKEGERSRSGKLSSGLPQQKPQLDGRHSSS 548

Query: 577  SSCPAPLEGREAGQASPSGSCT-MTVAQSSG--QSTGNG--AVQLPQ-QQQHSHPNTATV 630
            SS  A  EG+  G  + + S +  TV+ S G  Q+TG+   +VQLPQ QQQ++HPNTATV
Sbjct: 549  SSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATV 608

Query: 631  APFIYRAHSENEGTALPSADSCTSPTKMDLS-YSKTAKQCLEEISGEDPETRRMRTVKNI 689
            APF+YR+ ++ EG    +A+S ++   ++ S ++KT +  LEE++GEDPE RR+RTVKNI
Sbjct: 609  APFLYRSQTDTEGNV--TAESSSTGVSVEPSHFTKTGQPALEELTGEDPEARRLRTVKNI 666

Query: 690  ADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACP 749
            ADLRQNLEETMSSLRGTQ++HSTLETTFD+ VTTE++GR+I +LT RPTP++WRLGQ+ P
Sbjct: 667  ADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSP 726

Query: 750  RLQAGDAPSLGAGYP-RSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSD 808
            RLQAGDAPS+G GYP R+  SRFI+T+  R++Y+ PLRR   SR  ++  +D+S+KA  +
Sbjct: 727  RLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDE 786

Query: 809  LDMSS-EVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPD-TATSRDII 866
            +D+    +D  GYMSDGD+L K++RTDDI SGYMTDGGL LYTR LNR+PD  A  R+ +
Sbjct: 787  MDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETL 846

Query: 867  QRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRT 926
            QR       DADSWDDSSSVSSG+SDT+DN+STDD+NT+SS+SSY+N    SRKN  ++T
Sbjct: 847  QRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQT 906

Query: 927  DSEKRSTTDET--WDSPEELKKPEEDFDS--HGDAGGKWKTVSSGLPEDPEKAGQ-KASL 981
            D+EK S  +    W S +++KK +   DS    + G KW+   S + ++ +K+   K + 
Sbjct: 907  DAEKHSQVERNSLW-SGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNP 965

Query: 982  SVSQTGSWRRGMSAQGGAP---SRQKAGTSALKTPG--KTDDAKASEKGKAPLKGSSLQR 1036
             +SQTGSWRRGM+AQ G     ++  A   ALKTPG  KTDDAK SEKG+   K S ++R
Sbjct: 966  VISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKR 1025

Query: 1037 SPSDAGKSSGDEGKKP-PSGIGRSTATS-SFGFKKPSGVGSS-AMITSSGATITSGSATL 1093
            SPSDAG+SSGDE KKP PS     TA + SFGFKK SG  +  AMIT+SG T+TS SATL
Sbjct: 1026 SPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATL 1085

Query: 1094 GKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRG 1153
            GKIPKS+A+  +S AGRK+S+DG+QNQDD  L +SS+T LQYRSLPRPSKS++       
Sbjct: 1086 GKIPKSSALVSRS-AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRN---GA 1141

Query: 1154 GHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVS 1213
            G+RSSTSSIDSN+SSKSAG    KLREP+K   G S P  VNQTDKEK     SD+ESV+
Sbjct: 1142 GNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKG--ISSDNESVA 1199

Query: 1214 LSGSPKSSPTSASACG-AQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS 1272
               S K +P +      AQ   QPG+KYPD+ASPT RRLFG K   K       E +K+S
Sbjct: 1200 SCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT-KQVPIATAENMKNS 1258

Query: 1273 SVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASS 1332
             V+ +P  T+ +QG+L+SPS G+G + S     GSSSPL++K  DL          LASS
Sbjct: 1259 VVISNPHATMTQQGNLDSPS-GSGVLSS-----GSSSPLYSKNVDLNQS------PLASS 1306

Query: 1333 PASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSH-----HGSLS 1387
            P+S HS  S  L W  N SSSSA SKD   +QS++SLHTS ESID+ LS      H S +
Sbjct: 1307 PSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSST 1366

Query: 1388 GLTTGTHEVQ-SLLMRTGSVRSTLSESM-----------------------QLDRNTLPK 1423
            GL   + +   +  +RT SV++TLSES                         LDRNTLPK
Sbjct: 1367 GLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPK 1426

Query: 1424 KGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSP 1483
            KGLRYTP+S+   QE+ KEWLRSHS GGLQDT   SP  S S+++S +  +++FS L SP
Sbjct: 1427 KGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASP 1486

Query: 1484 TNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEE 1543
            T ++Q +L  P+M+R++S+   D  +D Y DS+   S+ SL+E+ R +S SGSFRD  EE
Sbjct: 1487 TTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEE 1546

Query: 1544 VHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFE 1603
            VHGSSLSLVSSTSS+YST EEK  SE I KLRREL ASQEKV+ LT+QL+ANAHLVAAFE
Sbjct: 1547 VHGSSLSLVSSTSSVYSTPEEKCQSE-IRKLRRELDASQEKVSALTTQLTANAHLVAAFE 1605

Query: 1604 KSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPK--- 1660
            +SLGNMT RLQSLTMTAEQK+SEL ELR+TIE+LK QN+AAQAAI G +N P+   K   
Sbjct: 1606 QSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNG 1665

Query: 1661 -----DLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQ 1715
                 DLRIRRQHSS+SVSSINSATSHSS+GS  ++DSKKKK+KNW       LRSSFKQ
Sbjct: 1666 TAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNW-------LRSSFKQ 1718

Query: 1716 AFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNAGDCGSASMKPSQSASAICECTEAEA 1775
            AFGKKKS K  SSHSDIEE+TDSSLP+SPKLPHN     +  ++ S S S I EC ++EA
Sbjct: 1719 AFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEA 1778

Query: 1776 EIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETG 1835
            E ++QL++ELR+KE+KLTDIRLEALSSAH LDQ+REAMNRMQ+EIE LKAENDRLK+E+ 
Sbjct: 1779 ETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQ 1838

Query: 1836 NTAKPTRPPSESSSSTSSSSSRQSLGLSLNNLNITEAVSSDILLDDAGDATGHKDG-RSV 1894
             +   +R PS+ S S   +S RQS+GLS ++LN+TE+ S D+LLDD G+ +  K+G R V
Sbjct: 1839 GSGC-SRAPSQVSIS---ASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHV 1894

Query: 1895 KIIVSISKGYGRAKDQKSQAYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRIDTSTSLGL 1954
            KI+VS  +     +D +   +LIG IGVSGKTKWDVLDGV+RRLFKEY+  +D  + LGL
Sbjct: 1895 KIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGL 1954

Query: 1955 SSDCIASYCIGDLIRSHNLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPK 2014
            +SD +  Y IG++ RS+  E PELLPCGYLVG+N  I+V +KG+ ENSLDS VF++LIPK
Sbjct: 1955 NSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPK 2014

Query: 2015 PITQRYFNLLMEHHRIILSGPSGTGKTYLANKLAEYVITKSGRKKTEDAIATFNVDHKSS 2074
            PI QRY +LL+EH RIILSGPSGTGKTYLAN+L+EY++ + GR+ T+  IATFNVDHKSS
Sbjct: 2015 PILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSS 2074

Query: 2075 KELQQYLANLAEQCSADNNGVELPVVIILDNLHHVGSLSDIFNGFLNCKYNKCPYIIGTM 2134
            KEL+QYL+NLA+QC+++NN V++P+VIILDNLHHV SL +IFNG LNCKY+KCPYIIGTM
Sbjct: 2075 KELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTM 2134

Query: 2135 NQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIEIEIERNIRNNDLVKIIDW 2194
            NQ  SS+PNL+LHHNFRWVLCANHTEPVKGFLGR+LRRKL+E EI   +RN +LVKIIDW
Sbjct: 2135 NQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDW 2194

Query: 2195 IPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVEGSRVWFMDLWNYSLVPYILEAVREG 2254
            IPK WHHLN FLE HSSSDVTIGPRLFL CP+DV+GSRVWF DLWNYS++PY+LEAVREG
Sbjct: 2195 IPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREG 2254

Query: 2255 LQMYGKRTPWEDPSKWVLDTYPWSSATLPQESPALLQLRPEDVGYESCTSTKEATTSKHI 2314
            LQ+YG+R PWEDP+KWV+DTYPW+++    E P LLQLRPEDVG++  +  +E +TSK +
Sbjct: 2255 LQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQM 2314

Query: 2315 PQTDTEGDPLMNMLMKLQEAANYSSTQSCDSE--STSHHEDILDSSLESTL 2363
            P +D EGDPLMNMLM+LQEAANYSS QS DS+  S SHH+DILDSSLESTL
Sbjct: 2315 PPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL 2365


>gi|161169017 neuron navigator 2 isoform 4 [Homo sapiens]
          Length = 1493

 Score = 1720 bits (4454), Expect = 0.0
 Identities = 927/1517 (61%), Positives = 1143/1517 (75%), Gaps = 64/1517 (4%)

Query: 879  SWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDET- 937
            SWDDSSSVSSG+SDT+DN+STDD+NT+SS+SSY+N    SRKN  ++TD+EK S  +   
Sbjct: 9    SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS 68

Query: 938  -WDSPEELKKPEEDFDS--HGDAGGKWKTVSSGLPEDPEKAGQ-KASLSVSQTGSWRRGM 993
             W S +++KK +   DS    + G KW+   S + ++ +K+   K +  +SQTGSWRRGM
Sbjct: 69   LW-SGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127

Query: 994  SAQGGAP---SRQKAGTSALKTPG--KTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDE 1048
            +AQ G     ++  A   ALKTPG  KTDDAK SEKG+   K S ++RSPSDAG+SSGDE
Sbjct: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187

Query: 1049 GKKP-PSGIGRSTATS-SFGFKKPSGVGSS-AMITSSGATITSGSATLGKIPKSAAIGGK 1105
             KKP PS     TA + SFGFKK SG  +  AMIT+SG T+TS SATLGKIPKS+A+  +
Sbjct: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247

Query: 1106 SNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSN 1165
            S AGRK+S+DG+QNQDD  L +SS+T LQYRSLPRPSKS++       G+RSSTSSIDSN
Sbjct: 248  S-AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRN---GAGNRSSTSSIDSN 303

Query: 1166 VSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSA 1225
            +SSKSAG    KLREP+K   G S P  VNQTDKEK     SD+ESV+   S K +P + 
Sbjct: 304  ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKG--ISSDNESVASCNSVKVNPAAQ 361

Query: 1226 SACG-AQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLAR 1284
                 AQ   QPG+KYPD+ASPT RRLFG K   K       E +K+S V+ +P  T+ +
Sbjct: 362  PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT-KQVPIATAENMKNSVVISNPHATMTQ 420

Query: 1285 QGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGL 1344
            QG+L+SPS G+G + S     GSSSPL++K  DL          LASSP+S HS  S  L
Sbjct: 421  QGNLDSPS-GSGVLSS-----GSSSPLYSKNVDLNQS------PLASSPSSAHSAPSNSL 468

Query: 1345 VWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSH-----HGSLSGLTTGTHEVQ-S 1398
             W  N SSSSA SKD   +QS++SLHTS ESID+ LS      H S +GL   + +   +
Sbjct: 469  TWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLT 528

Query: 1399 LLMRTGSVRSTLSES-MQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGN 1457
              +RT SV++TLSES   LDRNTLPKKGLRYTP+S+   QE+ KEWLRSHS GGLQDT  
Sbjct: 529  PFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAA 588

Query: 1458 QSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQL 1517
             SP  S S+++S +  +++FS L SPT ++Q +L  P+M+R++S+   D  +D Y DS+ 
Sbjct: 589  NSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRF 648

Query: 1518 CGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRE 1577
              S+ SL+E+ R +S SGSFRD  EEVHGSSLSLVSSTSS+YST EEK  SE I KLRRE
Sbjct: 649  RNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSE-IRKLRRE 707

Query: 1578 LVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEML 1637
            L ASQEKV+ LT+QL+ANAHLVAAFE+SLGNMT RLQSLTMTAEQK+SEL ELR+TIE+L
Sbjct: 708  LDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELL 767

Query: 1638 KAQNSAAQAAIQGALNGPDHPPK--------DLRIRRQHSSESVSSINSATSHSSIGSGN 1689
            K QN+AAQAAI G +N P+   K        DLRIRRQHSS+SVSSINSATSHSS+GS  
Sbjct: 768  KKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNI 827

Query: 1690 DADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHN 1749
            ++DSKKKK+KNW       LRSSFKQAFGKKKS K  SSHSDIEE+TDSSLP+SPKLPHN
Sbjct: 828  ESDSKKKKRKNW-------LRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHN 880

Query: 1750 AGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQI 1809
                 +  ++ S S S I EC ++EAE ++QL++ELR+KE+KLTDIRLEALSSAH LDQ+
Sbjct: 881  GSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQL 940

Query: 1810 REAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNNLNI 1869
            REAMNRMQ+EIE LKAENDRLK+E+  +   +R PS+ S S   +S RQS+GLS ++LN+
Sbjct: 941  REAMNRMQSEIEKLKAENDRLKSESQGSGC-SRAPSQVSIS---ASPRQSMGLSQHSLNL 996

Query: 1870 TEAVSSDILLDDAGDATGHKDG-RSVKIIVSISKGYGRAKDQKSQAYLIGSIGVSGKTKW 1928
            TE+ S D+LLDD G+ +  K+G R VKI+VS  +     +D +   +LIG IGVSGKTKW
Sbjct: 997  TESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKW 1056

Query: 1929 DVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLPCGYLVGDN 1988
            DVLDGV+RRLFKEY+  +D  + LGL+SD +  Y IG++ RS+  E PELLPCGYLVG+N
Sbjct: 1057 DVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGEN 1116

Query: 1989 NIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGKTYLANKLA 2048
              I+V +KG+ ENSLDS VF++LIPKPI QRY +LL+EH RIILSGPSGTGKTYLAN+L+
Sbjct: 1117 TTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLS 1176

Query: 2049 EYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVVIILDNLHH 2108
            EY++ + GR+ T+  IATFNVDHKSSKEL+QYL+NLA+QC+++NN V++P+VIILDNLHH
Sbjct: 1177 EYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHH 1236

Query: 2109 VGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGR 2168
            V SL +IFNG LNCKY+KCPYIIGTMNQ  SS+PNL+LHHNFRWVLCANHTEPVKGFLGR
Sbjct: 1237 VSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGR 1296

Query: 2169 YLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDV 2228
            +LRRKL+E EI   +RN +LVKIIDWIPK WHHLN FLE HSSSDVTIGPRLFL CP+DV
Sbjct: 1297 FLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDV 1356

Query: 2229 EGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDTYPWSSATLPQESPA 2288
            +GSRVWF DLWNYS++PY+LEAVREGLQ+YG+R PWEDP+KWV+DTYPW+++    E P 
Sbjct: 1357 DGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPP 1416

Query: 2289 LLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSSTQSCDSE-- 2346
            LLQLRPEDVG++  +  +E +TSK +P +D EGDPLMNMLM+LQEAANYSS QS DS+  
Sbjct: 1417 LLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSN 1476

Query: 2347 STSHHEDILDSSLESTL 2363
            S SHH+DILDSSLESTL
Sbjct: 1477 SNSHHDDILDSSLESTL 1493



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 183/879 (20%), Positives = 320/879 (36%), Gaps = 124/879 (14%)

Query: 358  SPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAF 417
            S   +S +  P +S+      S ++ M  +  +   RT    P      P  G  DD   
Sbjct: 105  SDKSTSGKKNPVISQ----TGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKV 160

Query: 418  SESGEMEGFNSGLNSGGSTNSSPKVSP-KLAPPKAG-SKNLSNKKSLLQPKEKEEKNRDK 475
            SE G +               SPK S  K +P  AG S    +KK L         N + 
Sbjct: 161  SEKGRL---------------SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANS 205

Query: 476  NKVCTEKPVKEEKDQVTEMAPKKTSKIASL--IPKGSKTTAAKKESLIPSSSGIPKPGSK 533
                 +         +T      TS+ A+L  IPK S        +L+  S+G  +  S 
Sbjct: 206  FGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSS--------ALVSRSAG--RKSSM 255

Query: 534  VPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASP 593
                 Q     + +S+ + ++R+    PS+S S+     ++S SS  + +  + AG   P
Sbjct: 256  DGAQNQDDGYLALSSRTNLQYRSLP-RPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVP 314

Query: 594  SGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCT 653
                    ++++  S+  G V    +++    +  +VA       S N     P+A   +
Sbjct: 315  K---LREPSKTALGSSLPGLVNQTDKEKGISSDNESVA-------SCNSVKVNPAAQPVS 364

Query: 654  SPTKMDL----SYSKTAKQCLEEISGEDPETR-RMRTVKNIADLRQNLEETMSSLRGTQI 708
            SP +  L     Y   A   L  + G  P  +  + T +N+ +        +S+   T  
Sbjct: 365  SPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKN-----SVVISNPHATMT 419

Query: 709  SHSTLETTFDSTVTTEVNGRTI--PNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGY-PR 765
                L++   S V +  +   +   N+    +P+      A     A  APS    +   
Sbjct: 420  QQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPL------ASSPSSAHSAPSNSLTWGTN 473

Query: 766  SGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGD 825
            + +S  +  D   F   + L  +  S       ID+S  +      +S   +     D D
Sbjct: 474  ASSSSAVSKDGLGFQSVSSLHTSCES-------IDISLSSGGVPSHNSSTGLIASSKD-D 525

Query: 826  ILGKSLRTDDINSGYM-TDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSS 884
             L   +RT+ + +    +D  L+  T     +  T TS+   Q        DA  W  S 
Sbjct: 526  SLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQE-------DAKEWLRSH 578

Query: 885  SVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEEL 944
            S + GL DT  N         S  SS S++T PS         +   + T  +  +P  L
Sbjct: 579  S-AGGLQDTAAN---------SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTML 628

Query: 945  KKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQK 1004
            +       S  +A G++   +     +   +  + S ++S++GS+R G     G      
Sbjct: 629  RT-----HSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHG------ 677

Query: 1005 AGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSS 1064
               S+L     T    ++ + K   +   L+R   DA +      +K  +   + TA + 
Sbjct: 678  ---SSLSLVSSTSSVYSTPEEKCQSEIRKLRRE-LDASQ------EKVSALTTQLTANAH 727

Query: 1065 FGFKKPSGVGSSAM-ITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDV 1123
                    +G+  + + S   T     + L ++ K+  +  K NA  + +++G  N  + 
Sbjct: 728  LVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPE- 786

Query: 1124 VLHVSSKTTLQYRSL---PRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLRE 1180
             L+     T Q   L    + S  S S I     H S  S+I+S+   K      + LR 
Sbjct: 787  -LNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKK---RKNWLRS 842

Query: 1181 PTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPK 1219
              K   G+        +  + E++  S     SL  SPK
Sbjct: 843  SFKQAFGKKKSPKSASSHSDIEEMTDS-----SLPSSPK 876


>gi|169218146 PREDICTED: similar to neuron navigator 3, partial [Homo
            sapiens]
          Length = 733

 Score = 1467 bits (3799), Expect = 0.0
 Identities = 733/733 (100%), Positives = 733/733 (100%)

Query: 1631 RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 1690
            RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND
Sbjct: 1    RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 60

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 1750
            ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA
Sbjct: 61   ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 120

Query: 1751 GDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIR 1810
            GDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIR
Sbjct: 121  GDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIR 180

Query: 1811 EAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNNLNIT 1870
            EAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNNLNIT
Sbjct: 181  EAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNNLNIT 240

Query: 1871 EAVSSDILLDDAGDATGHKDGRSVKIIVSISKGYGRAKDQKSQAYLIGSIGVSGKTKWDV 1930
            EAVSSDILLDDAGDATGHKDGRSVKIIVSISKGYGRAKDQKSQAYLIGSIGVSGKTKWDV
Sbjct: 241  EAVSSDILLDDAGDATGHKDGRSVKIIVSISKGYGRAKDQKSQAYLIGSIGVSGKTKWDV 300

Query: 1931 LDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLPCGYLVGDNNI 1990
            LDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLPCGYLVGDNNI
Sbjct: 301  LDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLPCGYLVGDNNI 360

Query: 1991 ITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGKTYLANKLAEY 2050
            ITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGKTYLANKLAEY
Sbjct: 361  ITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGKTYLANKLAEY 420

Query: 2051 VITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVVIILDNLHHVG 2110
            VITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVVIILDNLHHVG
Sbjct: 421  VITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVVIILDNLHHVG 480

Query: 2111 SLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYL 2170
            SLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYL
Sbjct: 481  SLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYL 540

Query: 2171 RRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVEG 2230
            RRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVEG
Sbjct: 541  RRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVEG 600

Query: 2231 SRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDTYPWSSATLPQESPALL 2290
            SRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDTYPWSSATLPQESPALL
Sbjct: 601  SRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDTYPWSSATLPQESPALL 660

Query: 2291 QLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSSTQSCDSESTSH 2350
            QLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSSTQSCDSESTSH
Sbjct: 661  QLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSSTQSCDSESTSH 720

Query: 2351 HEDILDSSLESTL 2363
            HEDILDSSLESTL
Sbjct: 721  HEDILDSSLESTL 733


>gi|27262622 neuron navigator 1 [Homo sapiens]
          Length = 1874

 Score = 1264 bits (3270), Expect = 0.0
 Identities = 786/1903 (41%), Positives = 1106/1903 (58%), Gaps = 198/1903 (10%)

Query: 518  ESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASAS 577
            + +  +  G+ K GSK    ++      T SK        KGSP+     P+     +  
Sbjct: 113  DDMAKAPKGLGKVGSKG---REAPLMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLG 169

Query: 578  SCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRA 637
              P+ +      +  P            G+S         + Q+ S P        +  A
Sbjct: 170  K-PSRIPRGPYAEVKPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGP--------VPSA 220

Query: 638  HSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGE---DPETRRMRTVKNIADLRQ 694
              + E   L          K+D     T    LE++      DPE++R RTV+N+ DLRQ
Sbjct: 221  KGQEERAFL----------KVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQ 270

Query: 695  NLEETMSSLRGTQISHSTLETT-FDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQA 753
            NLEETMSSLRG+Q++HS+LE T +DS    + N R++ +L++R +P++WR GQ+ PRLQA
Sbjct: 271  NLEETMSSLRGSQVTHSSLEMTCYDSD---DANPRSVSSLSNRSSPLSWRYGQSSPRLQA 327

Query: 754  GDAPSLGAGYPRSGTSR-FIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMS 812
            GDAPS+G      GT   ++H + + + +T P+R  + S+L ++S++++ E   SD    
Sbjct: 328  GDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMR--SPSKLSHISRLELVESLDSD---- 381

Query: 813  SEVDV-GGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVH 871
             EVD+  GYMSD D++GK++  DD                                    
Sbjct: 382  -EVDLKSGYMSDSDLMGKTMTEDD------------------------------------ 404

Query: 872  DVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQ--LRTDSE 929
            D+T     WD+SSS+SSGLSD  DN+S+++ N +SS++S  +    SR+N+   LRTDSE
Sbjct: 405  DITT---GWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSE 461

Query: 930  KRSTTDE--TWDSPEELKKPEE-DFDSHG----DAGGKWKTVSSGLPEDPEKAGQ-KASL 981
            KRS  +   +W S  E K P++ ++DS          KW+       +D  K G+ K  +
Sbjct: 462  KRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPI 521

Query: 982  SVSQTGSWRRGMSAQGGAPSR-QKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSD 1040
            S+   GS ++G +      S       SALK  GK +  KA++KGK  +K + LQRS SD
Sbjct: 522  SLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPE-GKATDKGKLAVKNTGLQRSSSD 580

Query: 1041 AGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSA 1100
            AG+    + KKPPSGI R + + SFG+KKP     +A +  +G     GSATL KI KS+
Sbjct: 581  AGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTG-----GSATLSKIQKSS 635

Query: 1101 AIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPG-RGGHRSST 1159
             I  K   GRKTSLD S + +   L   +++ +QYRSLPRP+KSS+  + G RGG R  +
Sbjct: 636  GIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVS 695

Query: 1160 SSID-SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVS----DSESVSL 1214
            SSID S +S+K  G T S+L+EPTK+ SGR++P  VNQTD+EKEK        DS+++SL
Sbjct: 696  SSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISL 755

Query: 1215 S--GSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS 1272
               GSP+S+P +      Q      +K  ++     R    AK+  K  S  N + V S+
Sbjct: 756  KSIGSPESTPKN------QASHPTATKLAELPPTPLRAT--AKSFVKPPSLANLDKVNSN 807

Query: 1273 SV-MPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLAS 1331
            S+ +PS S T       + P     S  S G L    +P                     
Sbjct: 808  SLDLPSSSDTTHAS---KVPDLHATSSASGGPLPSCFTP--------------------- 843

Query: 1332 SPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLT- 1390
            SPA + +  S        + S  +  K+T  Y  ++ LH S ES+ +P+S   +    T 
Sbjct: 844  SPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTP 903

Query: 1391 ---------TGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGK 1441
                       T E    L  +GS R+   +S Q DRNTLPKKGLRY   S    QEE K
Sbjct: 904  VPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQS----QEETK 959

Query: 1442 EWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNS 1501
            E   SH+ GGL ++ +QS L SP A+  S + K   +N+VSPT  +      P + RSNS
Sbjct: 960  ERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAATT-----PRITRSNS 1014

Query: 1502 IPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYST 1561
            IP  +++F+LY  SQ+ GS  SL ERP+ +  SGSFRD  ++VHGS LSL SS SS YS+
Sbjct: 1015 IPTHEAAFELYSGSQM-GSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSS 1073

Query: 1562 AEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAE 1621
            AEE+  SEQI KLRREL +SQEKVATLTSQLSANA+LVAAFE+SL NMT RL+ L  TAE
Sbjct: 1074 AEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAE 1133

Query: 1622 QKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATS 1681
            +K++EL++LRETI+ LK +NS AQA IQGALN  +  PK+LRI+RQ+SS+S+SS+NS TS
Sbjct: 1134 EKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITS 1193

Query: 1682 HSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELT--DSS 1739
            HSSIGS  DAD+KKKKKK+W       LRSSF +AF  KK  K  SS+SDIEE+   DSS
Sbjct: 1194 HSSIGSSKDADAKKKKKKSW-------LRSSFNKAFSIKKGPKSASSYSDIEEIATPDSS 1246

Query: 1740 LPASPKLPHNAGDCGSASMKPSQSASAICECTEA-------------------EAEIILQ 1780
             P+SPKL H + +  S S+K S S+S   + TE                    E + + +
Sbjct: 1247 APSSPKLQHGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSE 1306

Query: 1781 LKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTAKP 1840
            L+SEL EKE+KLTDIRLEAL+SAH LDQ+RE M+ MQ E+++LKAENDRLK   G ++  
Sbjct: 1307 LRSELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGS 1366

Query: 1841 TRPPSESSSSTSSSSSRQSLGLSLNNLNITEAVSSDILLDDAGDATGHKDGRSVKIIVSI 1900
            T  P +   S++ SS R+SLGL+L +        +D+   D     G K+  +++++V +
Sbjct: 1367 T--PGQVPGSSALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRM 1424

Query: 1901 SKGYGRAKDQKSQAYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIA 1960
               +    D K Q + +G   VSGK  W +LD  + ++FK+Y+ ++D +++LGLS++ I 
Sbjct: 1425 PPQHIIKGDLKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIH 1484

Query: 1961 SYCIGDLIRSHNLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRY 2020
             Y I  + R  + E PE+ PC    G NNI +V+LKG++E  +DS VF+TLIPKP+ Q Y
Sbjct: 1485 GYSISHVKRVLDAEPPEMPPCRR--GVNNI-SVSLKGLKEKCVDSLVFETLIPKPMMQHY 1541

Query: 2021 FNLLMEHHRIILSGPSGTGKTYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQY 2080
             +LL++H R++LSGPSGTGKTYL N+LAEY++ +SGR+ TE  ++TFN+  +S K+LQ Y
Sbjct: 1542 ISLLLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLY 1601

Query: 2081 LANLAEQCSADNNGVELPVVIILDNLHHVGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSS 2140
            L+NLA Q   +    ++P+VI+LD+L   GS+S++ NG L CKY+KCPYIIGT NQ V  
Sbjct: 1602 LSNLANQIDRETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKM 1661

Query: 2141 SPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIEIEIERNIRNNDLVKIIDWIPKTWH 2200
            +PN  LH +FR +  +N+ EP  GFL RYLRRKL+E + + N    +L++++DW+PK W+
Sbjct: 1662 TPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWY 1721

Query: 2201 HLNSFLETHSSSDVTIGPRLFLPCPMDVEGSRVWFMDLWNYSLVPYILEAVREGLQMYGK 2260
            HL++FLE HS+SD  IGP  FL CP+ +E  R WF+DLWN S++PY+ E  ++G++++G+
Sbjct: 1722 HLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQ 1781

Query: 2261 RTPWEDPSKWVLDTYPWSSATLPQESPALLQLRPEDVGYESCTSTKEATTSKHIPQTDTE 2320
            +  WEDP +WV DT PW SA   Q+   L  L P  VG  S  S  E  T K    +  +
Sbjct: 1782 KAAWEDPVEWVRDTLPWPSA--QQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLD 1839

Query: 2321 GDPLMNMLMKLQEAANYSSTQSCDSESTSHHEDILDSSLESTL 2363
             DPLM ML+KLQEAANY  +           E ILD +L++TL
Sbjct: 1840 SDPLMAMLLKLQEAANYIESPD--------RETILDPNLQATL 1874


>gi|239750047 PREDICTED: similar to neuron navigator 2, partial [Homo
            sapiens]
          Length = 453

 Score =  701 bits (1808), Expect = 0.0
 Identities = 324/451 (71%), Positives = 388/451 (86%), Gaps = 2/451 (0%)

Query: 1915 YLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLE 1974
            +LIG IGVSGKTKWDVLDGV+RRLFKEY+  +D  + LGL+SD +  Y IG++ RS+  E
Sbjct: 3    FLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSE 62

Query: 1975 VPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSG 2034
             PELLPCGYLVG+N  I+V +KG+ ENSLDS VF++LIPKPI QRY +LL+EH RIILSG
Sbjct: 63   TPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSG 122

Query: 2035 PSGTGKTYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNG 2094
            PSGTGKTYLAN+L+EY++ + GR+ T+  IATFNVDHKSSKEL+QYL+NLA+QC+++NN 
Sbjct: 123  PSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNA 182

Query: 2095 VELPVVIILDNLHHVGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVL 2154
            V++P+VIILDNLHHV SL +IFNG LNCKY+KCPYIIGTMNQ  SS+PNL+LHHNFRWVL
Sbjct: 183  VDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVL 242

Query: 2155 CANHTEPVKGFLGRYLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDV 2214
            CANHTEPVKGFLGR+LRRKL+E EI   +RN +LVKIIDWIPK WHHLN FLE HSSSDV
Sbjct: 243  CANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDV 302

Query: 2215 TIGPRLFLPCPMDVEGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDT 2274
            TIGPRLFL CP+DV+GSRVWF DLWNYS++PY+LEAVREGLQ+YG+R PWEDP+KWV+DT
Sbjct: 303  TIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDT 362

Query: 2275 YPWSSATLPQESPALLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEA 2334
            YPW+++    E P LLQLRPEDVG++  +  +E +TSK +P +D EGDPLMNMLM+LQEA
Sbjct: 363  YPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEA 422

Query: 2335 ANYSSTQSCDSE--STSHHEDILDSSLESTL 2363
            ANYSS QS DS+  S SHH+DILDSSLESTL
Sbjct: 423  ANYSSPQSYDSDSNSNSHHDDILDSSLESTL 453


>gi|239747580 PREDICTED: similar to NAV1 protein [Homo sapiens]
          Length = 559

 Score =  516 bits (1328), Expect = e-145
 Identities = 263/574 (45%), Positives = 380/574 (66%), Gaps = 15/574 (2%)

Query: 1790 LKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSS 1849
            +KLTDIRLEAL+SAH LDQ+RE M+ MQ E+++LKAENDRLK   G ++  T  P +   
Sbjct: 1    MKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGST--PGQVPG 58

Query: 1850 STSSSSSRQSLGLSLNNLNITEAVSSDILLDDAGDATGHKDGRSVKIIVSISKGYGRAKD 1909
            S++ SS R+SLGL+L +        +D+   D     G K+  +++++V +   +    D
Sbjct: 59   SSALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKGD 118

Query: 1910 QKSQAYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIR 1969
             K Q + +G   VSGK  W +LD  + ++FK+Y+ ++D +++LGLS++ I  Y I  + R
Sbjct: 119  LKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKR 178

Query: 1970 SHNLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHR 2029
              + E PE+ PC    G NNI +V+LKG++E  +DS VF+TLIPKP+ Q Y +LL++H R
Sbjct: 179  VLDAEPPEMPPCRR--GVNNI-SVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRR 235

Query: 2030 IILSGPSGTGKTYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCS 2089
            ++LSGPSGTGKTYL N+LAEY++ +SGR+ TE  ++TFN+  +S K+LQ YL+NLA Q  
Sbjct: 236  LVLSGPSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQID 295

Query: 2090 ADNNGVELPVVIILDNLHHVGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHN 2149
             +    ++P+VI+LD+L   GS+S++ NG L CKY+KCPYIIGT NQ V  +PN  LH +
Sbjct: 296  RETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLS 355

Query: 2150 FRWVLCANHTEPVKGFLGRYLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETH 2209
            FR +  +N+ EP  GFL RYLRRKL+E + + N    +L++++DW+PK W+HL++FLE H
Sbjct: 356  FRMLTFSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKH 415

Query: 2210 SSSDVTIGPRLFLPCPMDVEGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSK 2269
            S+SD  IGP  FL CP+ +E  R WF+DLWN S++PY+ E  ++G++++G++  WEDP +
Sbjct: 416  STSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVE 475

Query: 2270 WVLDTYPWSSATLPQESPALLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLM 2329
            WV DT PW SA   Q+   L  L P  VG  S  S  E  T K    +  + DPLM ML+
Sbjct: 476  WVRDTLPWPSA--QQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLL 533

Query: 2330 KLQEAANYSSTQSCDSESTSHHEDILDSSLESTL 2363
            KLQEAANY  +           E ILD +L++TL
Sbjct: 534  KLQEAANYIESPD--------RETILDPNLQATL 559


>gi|16975496 cortactin binding protein 2 [Homo sapiens]
          Length = 1663

 Score =  115 bits (287), Expect = 7e-25
 Identities = 107/446 (23%), Positives = 190/446 (42%), Gaps = 56/446 (12%)

Query: 1876 DILLDDAGDATGHKDGRSVKIIVSISK----GYGRAKDQKSQAYLIGSIGVSGKTKWDVL 1931
            D+  DD      + +   + + +S+ +     YG   D       I ++ +  +T WD  
Sbjct: 952  DVATDDCKHLLENLNALKIPLRISVGEIEPSNYG--SDDLECENTICALNIRKQTSWDDF 1009

Query: 1932 DGVIRRLFKEYVFRID---------------TSTSLGLSSDCIASYCIGDLIRSHNLEVP 1976
               + +    +   I                T +++GLS+  I S  +G++  S      
Sbjct: 1010 SKAVSQALTNHFQAISSDGWWSLEDVTCNNTTDSNIGLSARSIRSITLGNVPWSVGQSFA 1069

Query: 1977 ELLPCGYLVGDN-NIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGP 2035
            +  P  ++  +    ITV L G +E  L S  + ++IP  + Q Y  L+ ++H +I  GP
Sbjct: 1070 QS-PWDFMRKNKAEHITVLLSGPQEGCLSSVTYASMIPLQMMQNYLRLVEQYHNVIFHGP 1128

Query: 2036 SGTGKTYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKE-LQQYLANLAEQCSADNNG 2094
             G+ + Y+ ++LA  +  +         I    VD   SKE L     + A       + 
Sbjct: 1129 EGSLQDYIVHQLALCLKHRQMAAGFSCEIVRAEVDAGFSKEQLLDLFISSACLIPVKQSP 1188

Query: 2095 VELPVVIILDNLHHVGSLSDIFNGFL----------NCKYNK------CPY------IIG 2132
             +  ++IIL+NL    SLS++   FL           C + K      C Y      ++G
Sbjct: 1189 SKKKIIIILENLEK-SSLSELLRDFLAPLENRSTESPCTFQKGNGLSECYYFHENCFLMG 1247

Query: 2133 TMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLI-EIEIERNIRNNDLVKI 2191
            T+ +      +L +  +FRWV      EP++G L R+LRRK++ + + +     + + KI
Sbjct: 1248 TIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGLLQRFLRRKVVNKFKGQAPSPCDPVCKI 1307

Query: 2192 IDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDVEGSRV---WFMDLWNYSLVPYIL 2248
            +DW    W  LNS L    + +  +GP+ FL CP+    ++V   W   LWN  + P + 
Sbjct: 1308 VDWALSVWRQLNSCLARLGTPEALLGPKYFLSCPVVPGHAQVTVKWMSKLWNGVIAPRVQ 1367

Query: 2249 EAVREGLQM-----YGKRTPWEDPSK 2269
            EA+     +     +G+ T    PS+
Sbjct: 1368 EAILSRASVKRQPGFGQTTAKRHPSQ 1393


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score =  106 bits (264), Expect = 3e-22
 Identities = 246/1206 (20%), Positives = 437/1206 (36%), Gaps = 142/1206 (11%)

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEG 373
            T   P A +  + +++    + ++ +K S T+T  T    +T  SPT S   +   +S  
Sbjct: 5    TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI-VSISGS 63

Query: 374  VKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
              T  S   S         + T         +  S  G +    S +G      S + S 
Sbjct: 64   EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 434  GSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
             +TNS+   S       AGS+  +                  + V +E       D  T 
Sbjct: 124  TTTNSTTS-SETTVTSTAGSETTT-----------------VSTVGSETTTAYTADSETT 165

Query: 494  MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTAS 548
             A    S++ ++   GS       E++ PS++G     +   GS+  TV  T S  +TAS
Sbjct: 166  AASTTGSEMTTVFTAGS-------ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218

Query: 549  KESEK--FRTTKGSPSQSLS---KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVA- 602
                +    +T GS +  +S      T+  A + +  A  E  E   A    S T T + 
Sbjct: 219  TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278

Query: 603  ---QSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYR-AHSENEGTALPSADSCTSPTKM 658
               +++  ST      +           +T+ P   + + + +E T + +A S T     
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 659  DLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFD 718
              S + T        +G +  T  +   +   D     E T +S  G++ + ++ E +  
Sbjct: 339  VGSETTTV-----STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 719  STVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSR 778
            +TV+T  +  T  ++T   T  T   G                       S       + 
Sbjct: 394  TTVSTTGSETTTVSITDSETTTTCTEG-----------------------SEMTAVSTTV 430

Query: 779  FMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINS 838
            F  TT     +   + + S  + +  ++   + ++    G         G    T   N+
Sbjct: 431  FETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTAS-NT 489

Query: 839  GYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIS 898
            G  T     + + +     + + +  +   G    TV  +  ++++  ++G   T   +S
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT--TVS 547

Query: 899  TDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAG 958
            T  L TT++ +  S +T  S    +  TDS + S T                  +   AG
Sbjct: 548  TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT-----------------TAASTAG 590

Query: 959  GKWKTVSSGLPED-PEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD 1017
             +  TVS+   E+         + S S TGS     S      +      S   T   TD
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 1018 DAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSGIGRSTAT-SSFGFKKPS 1071
                SE       GS     S + S +    ++G E      G G +T + +     K S
Sbjct: 651  ----SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVS 706

Query: 1072 GVGSSAMITSS-GATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSK 1130
              GS   ITS+ G+ IT+ S T  +   ++  G ++      S +GS+         S+ 
Sbjct: 707  TTGSETTITSTEGSEITTASITGSETTTASTEGSETTT---ASTEGSET-------TSAS 756

Query: 1131 TTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDS---NVSSKSAGATT--SKLREPTKIG 1185
            TT    +    + S T+     G   +  S+I S    VS+ S+  TT  ++  E T   
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1186 SGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIAS 1245
            +  S   TV+    E    + + SE+ + + +  S  T+AS  G++            AS
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE---------TTTAS 867

Query: 1246 PTFRRLFGAKAGGKSASAPNTEG--VKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGG 1303
                    A   G   +  +TEG    ++S   S +TT + +GS  +  S TGS  +   
Sbjct: 868  TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 1304 LSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY 1363
              GS +   +      T V +      +  A     T+   + +   ++S+AGS+ T   
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT-- 985

Query: 1364 QSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPK 1423
             S     T++ SI+      GS +   + T    + +  TG+  +T++ +   +  T+  
Sbjct: 986  VSTAGSETTTASIE------GSETTTVSSTGSETTTVSTTGT-ETTITSTEGSETTTVTT 1038

Query: 1424 KG-----LRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFS 1478
             G     +  T S       EG E     +TG    T + + L   + +S+S +G    S
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTVSTSGSGTTTAS 1097

Query: 1479 NLVSPT 1484
               S T
Sbjct: 1098 TAGSET 1103



 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 253/1241 (20%), Positives = 449/1241 (36%), Gaps = 127/1241 (10%)

Query: 345  STMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPS 404
            +T ++   S T T  T  S+      +    TA S   S   K     + T +      +
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253

Query: 405  SGPS-DGGKDDDAFSESGEME-----GFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSN 458
            +  S +  + + AF+E  +       GF +   +  +T S P ++  +      +  +  
Sbjct: 254  TAASTEDSETNTAFTEDSKTTTASTTGFET--TAASTTGSEPTMASTMGSETTMASTIGP 311

Query: 459  KKSLLQPKEKE--------EKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGS 510
            + + +     E         +    + V +E          T  A    S+ ++    GS
Sbjct: 312  ETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGS 371

Query: 511  KTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
            +TT A  E    +++     GS+  TV  T S  +T S    +  TT    S+  +   T
Sbjct: 372  ETTTASTEGSETTTASTE--GSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT 429

Query: 571  MEKASASSCP------APLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSH 624
            + + + +S        A     E   AS  GS T TV  ++G  T        +    S+
Sbjct: 430  VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVT-TAGSETKTAYTTGSETTTASN 488

Query: 625  PNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMR 684
                T   F   + +    T   S  +  S T  +++   T       +S    ET  + 
Sbjct: 489  TGLETTTVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS 547

Query: 685  TVKNIADLRQNLEETMSSLRG---TQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMT 741
            T          LE T +S  G   T +S +  ETT DST   E +G T  +     T   
Sbjct: 548  TT--------GLETTTTSTEGSEMTTVSTTGAETTTDST---EGSGTTAASTAGSETTTV 596

Query: 742  WRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDM 801
                         D+ +  A    S T+    T       +T           +     +
Sbjct: 597  STADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV 656

Query: 802  SEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTAT 861
            S   S     S+E   G   +     G         SG  T   +++      ++  T +
Sbjct: 657  STTGSERTITSTE---GSETTTVSATGSETTVSTEGSGTTT---VSITGSETTKVSTTGS 710

Query: 862  SRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKN 921
               I      ++T  + +  ++++ S+  S+T    ST+   TTS+ ++ S  T  S  +
Sbjct: 711  ETTITSTEGSEITTASITGSETTTASTEGSETT-TASTEGSETTSASTTGSETTTASTTS 769

Query: 922  TQLRTDSEKRSTT-------DETWDSPEELKKPEEDFDSHGDA------GGKWKTVSSGL 968
            ++    S   S T        ET        K    F  + +         +  TVS+  
Sbjct: 770  SETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAG 829

Query: 969  PED--PEKAGQKASLSVSQTGSWRRGMSAQGG---APSRQKAGTSALKTPGK---TDDAK 1020
             E      AG + + + S  GS     S +G      S + + T+   T G    T   +
Sbjct: 830  SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTE 889

Query: 1021 ASEKGKAPLKGSSLQRSPSDAGK-----SSGDEGKKPPSGIGRSTATSSFGFKKP--SGV 1073
             SE      +GS    + ++  +     ++G E     +    +T  S+ G +    S  
Sbjct: 890  GSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTT 949

Query: 1074 GSSAMITSSGATITSGSATLGKIPKSAAIGGK-----SNAGRKT---SLDGSQNQDDVVL 1125
            GS  +  S+  + T+   T+G    +A+  G      S AG +T   S++GS+     V 
Sbjct: 950  GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETT--TVS 1007

Query: 1126 HVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIG 1185
               S+TT    +    + +ST G        S T+++ +  S  +A  TT    E T   
Sbjct: 1008 STGSETTTVSTTGTETTITSTEG--------SETTTVTTAGSETTAVYTTGS--ETTTTS 1057

Query: 1186 SGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQ--PGSKYPDI 1243
            +  S   TV+ T  E    + +D E+ ++S S  S  T+AS  G++       GSK    
Sbjct: 1058 TEGSETTTVSTTGSETTTASTADLETTTVSTSG-SGTTTASTAGSETTTVYITGSKTTTA 1116

Query: 1244 ASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMP--SPSTTLARQGSLESPSSGTGSMGSA 1301
            ++        +    ++ +A +T G + ++V    S +TT++  GS  + SS  GS  + 
Sbjct: 1117 STEGSEATTVSTTSSETTTA-STTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATT 1175

Query: 1302 GGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSK--- 1358
                GS +   +     TT   +      ++  S     +     +   + SSAGS+   
Sbjct: 1176 TSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNT 1235

Query: 1359 -----------DTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTG-SV 1406
                        T S +   +  T SE+  + ++  G+ +  TT +     L   T  S+
Sbjct: 1236 AFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSI 1295

Query: 1407 RSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEW---LRSHSTGG--LQDTGNQSPL 1461
            +   +  M   R T    G R T SS       G ++     SH+  G  L  +G  +  
Sbjct: 1296 QPITNTPMSGTRTT----GTRLTASS-SVTMAPGMDFTASAASHTVPGIVLNTSGLGTST 1350

Query: 1462 VSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSI 1502
            +  S+ +S+   +    +   PT+ S F   GP  M +N++
Sbjct: 1351 MGASSTTSAHGVRTTTGSTREPTS-STFQETGPVSMGTNTV 1390



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 171/889 (19%), Positives = 323/889 (36%), Gaps = 70/889 (7%)

Query: 999  APSRQKAGTSALKTPGKTDDA--KASEKGKAPLKGSSLQRSPSDAGKS------SGDEGK 1050
            AP+     T+A  T  +T     KASE   A   GS    +PS  G        SG E  
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT-TPSPTGSQTTIVSISGSEIT 66

Query: 1051 KPPSGIGRSTATSSFGF--KKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNA 1108
               +    +T  SS G      S  GS   ++++G+  T+ S T  +    +A+G ++  
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 1109 GRKTSLDGSQ-----NQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSID 1163
               TS + +      ++   V  V S+TT  Y +    + +ST+G        + + +I 
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 1164 SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES--VSLSGSPKSS 1221
             + +       ++   E T + +  S   T +    E    +   SE+  VS +GS  + 
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 1222 PTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS--SVMPSPS 1279
             T+ S   A       +   + A     +   A   G   +A +T G + +  S M S +
Sbjct: 247  STAGSETTAASTEDSET---NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 1280 TTLARQG----SLESPSSGTGSMGSAGGLSGSSSPLFNKPSDL-TTDVISLSHSLASSPA 1334
            T  +  G     + + SS   ++ +AG  +  +S + ++ + + TT   + + S+  S  
Sbjct: 304  TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTH 1394
            S  S T+G     A+   S   +  T   ++ T   T SE+  + ++     S  TT   
Sbjct: 364  STDS-TTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITD----SETTTTCT 418

Query: 1395 EVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQD 1454
            E   +   + +V  T + S +    T+       T ++     E          T     
Sbjct: 419  EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478

Query: 1455 TGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDD 1514
            TG+++   S + + ++           + T  S+      +     ++  + S       
Sbjct: 479  TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVST 538

Query: 1515 SQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKL 1574
            +   GS T+       +S +G    +     GS ++ VS+T      AE    S +    
Sbjct: 539  T---GSETT------TVSTTG-LETTTTSTEGSEMTTVSTTG-----AETTTDSTEGSGT 583

Query: 1575 RRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELI----EL 1630
                 A  E     T+         A  E +  + TG   S T TA    SE      E 
Sbjct: 584  TAASTAGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEG 640

Query: 1631 RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 1690
             ET  +    +     +  G+        + +       + +VS+  S T+ S+ GSG  
Sbjct: 641  SETTTVSTTDSETTMVSTTGS-------ERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 1750
              S    +   V++ GSE  ++     G + +T   +        T+ S   +       
Sbjct: 694  TVSITGSETTKVSTTGSE--TTITSTEGSEITTASITGSETTTASTEGSETTTAST--EG 749

Query: 1751 GDCGSASMKPSQSASAICECTEAEAEIIL----QLKSELREKELKLTDIRLEALSSAHHL 1806
             +  SAS   S++ +A    +E     I+     + S +  +  K++    +  +     
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 1807 DQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSS 1855
             +   A         +  A ++ + A T  +   T   +E S +T++S+
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score =  104 bits (259), Expect = 1e-21
 Identities = 245/1206 (20%), Positives = 436/1206 (36%), Gaps = 142/1206 (11%)

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEG 373
            T   P A +  + +++    + ++ +K S T+T  T    +T  SPT S   +   +S  
Sbjct: 5    TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI-VSISGS 63

Query: 374  VKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
              T  S   S         + T         +  S  G +    S +G      S + S 
Sbjct: 64   EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 434  GSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
             +TNS+   S       AGS+  +                  + V +E       D  T 
Sbjct: 124  TTTNSTTS-SETTVTSTAGSETTT-----------------VSTVGSETTTAYTADSETT 165

Query: 494  MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTAS 548
             A    S++ ++   GS       E++ PS++G     +   GS+  TV  T S  +TAS
Sbjct: 166  AASTTGSEMTTVFTAGS-------ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218

Query: 549  KESEK--FRTTKGSPSQSLS---KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVA- 602
                +    +T GS +  +S      T+  A + +  A  E  E   A    S T T + 
Sbjct: 219  TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278

Query: 603  ---QSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYR-AHSENEGTALPSADSCTSPTKM 658
               +++  ST      +           +T+ P   + + + +E T + +A S T     
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 659  DLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFD 718
              S + T        +G +  T  +   +   D     E T +S  G++ + ++ E +  
Sbjct: 339  VGSETTTV-----STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 719  STVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSR 778
            +TV+T  +  T  ++T   T  T   G                       S       + 
Sbjct: 394  TTVSTTGSETTTVSITDSETTTTCTEG-----------------------SEMTAVSTTV 430

Query: 779  FMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINS 838
            F  TT     +   + + S  + +  ++   + ++    G         G    T   N+
Sbjct: 431  FETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTAS-NT 489

Query: 839  GYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIS 898
            G  T     + + +     + + +  +   G    TV  +  ++++  ++G   T   +S
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT--TVS 547

Query: 899  TDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAG 958
            T  L TT++ +  S +T  S    +  TDS + S T                  +   AG
Sbjct: 548  TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT-----------------TAASTAG 590

Query: 959  GKWKTVSSGLPED-PEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD 1017
             +  TVS+   E+         + S S TGS     S      +      S   T   TD
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 1018 DAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSGIGRSTAT-SSFGFKKPS 1071
                SE       GS     S + S +    ++G E      G G +T + +     K S
Sbjct: 651  ----SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVS 706

Query: 1072 GVGSSAMITSS-GATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSK 1130
              GS    TS+ G+ IT+ S T  +   ++  G ++      S +GS+         S+ 
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT---ASTEGSET-------TSAS 756

Query: 1131 TTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDS---NVSSKSAGATT--SKLREPTKIG 1185
            TT    +    + S T+     G   +  S+I S    VS+ S+  TT  ++  E T   
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1186 SGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIAS 1245
            +  S   TV+    E    + + SE+ + + +  S  T+AS  G++            AS
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE---------TTTAS 867

Query: 1246 PTFRRLFGAKAGGKSASAPNTEG--VKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGG 1303
                    A   G   +  +TEG    ++S   S +TT + +GS  +  S TGS  +   
Sbjct: 868  TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 1304 LSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY 1363
              GS +   +      T V +      +  A     T+   + +   ++S+AGS+ T   
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT-- 985

Query: 1364 QSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPK 1423
             S     T++ SI+      GS +   + T    + +  TG+  +T++ +   +  T+  
Sbjct: 986  VSTAGSETTTASIE------GSETTTVSSTGSETTTVSTTGT-ETTITSTEGSETTTVTT 1038

Query: 1424 KG-----LRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFS 1478
             G     +  T S       EG E     +TG    T + + L   + +S+S +G    S
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTVSTSGSGTTTAS 1097

Query: 1479 NLVSPT 1484
               S T
Sbjct: 1098 TAGSET 1103



 Score = 71.6 bits (174), Expect = 8e-12
 Identities = 195/988 (19%), Positives = 343/988 (34%), Gaps = 87/988 (8%)

Query: 256  AAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTA 315
            A+ S S+   AS     + +  +        Y  G+E  ++      +     +   +T 
Sbjct: 446  ASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 316  GQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTP-SSDRLKPPVSEGV 374
                 S   + SA+      +++ + S  +T+ T    +T  S T   +       SE  
Sbjct: 506  ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT 564

Query: 375  KTAPSGQKSMLEKFK---LVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLN 431
              + +G ++  +  +      A TA       S+  S+      A SE+       S   
Sbjct: 565  TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624

Query: 432  SGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQP--KEKEEKNRDKNKVCTEKPVKEEKD 489
            +  +T+S    +              ++ +++     E+   + + ++  T      E  
Sbjct: 625  TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 490  QVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASK 549
              TE +   T  I      GS+TT  K  +    ++     GS++ T   T S  +TAS 
Sbjct: 685  VSTEGSGTTTVSIT-----GSETT--KVSTTGSETTTTSTEGSEITTASITGSETTTAST 737

Query: 550  ESEKFRT--TKGSPSQSLS----KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQ 603
            E  +  T  T+GS + S S    +  T    S+ +  A + G E   AS  GS T  V+ 
Sbjct: 738  EGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVST 797

Query: 604  SSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSEN--EGTALPSADSCTSPTKMDLS 661
            +S + T    V     +      TA+    +  A SE     TA     + TS    + +
Sbjct: 798  ASSKMT---TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 854

Query: 662  YSKTAKQCLEEISGEDPETRRMRTV--KNIADLRQNLEETMSSLRGTQISHSTLETTFDS 719
             + T        S E  ET    T+  +      +  E T +S  G++ + ++ E +  +
Sbjct: 855  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 914

Query: 720  TVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRF 779
            TV+T  +  T  +     T      G     +    + ++      S T     T  +  
Sbjct: 915  TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSET-----TTVTTM 969

Query: 780  MYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSG 839
               T     A S    +S    SE  ++ ++ S    V    S+   +  +     I S 
Sbjct: 970  GSETTTASTAGSETTTVSTAG-SETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS- 1027

Query: 840  YMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIST 899
              T+G           +    +    +     + T  +    ++++VS+  S+T    ST
Sbjct: 1028 --TEGS------ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETT-TAST 1078

Query: 900  DDLNTTSSVSSYSNITVPSRKNTQLRT---DSEKRSTTDETWDSPEELKKPEEDFDSHGD 956
             DL TT+  +S S  T  S   ++  T      K +T          +     +  +   
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1138

Query: 957  AGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG---APSRQKAGTSALKTP 1013
             G +  TV + + E         + +VS  GS     SA G      S + + T+   T 
Sbjct: 1139 TGSEMTTVFTTVSE---------TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTA 1189

Query: 1014 GK---TDDAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSG---------I 1056
            G    T     SE   A   GS     S   S ++   ++G E   P S          I
Sbjct: 1190 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1249

Query: 1057 GRSTATSSFGFKKPSGVG------SSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGR 1110
            G  T  +S    +P+         ++  IT+SGAT  S + +      + A         
Sbjct: 1250 GSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPIT 1309

Query: 1111 KTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPG----RGGHRSSTSSIDSNV 1166
             T + G++     +   SS T          + S T  +PG      G  +ST    S  
Sbjct: 1310 NTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHT--VPGIVLNTSGLGTSTMGASSTT 1367

Query: 1167 SSKSAGATTSKLREPTKIGSGRSSPVTV 1194
            S+     TT   REPT      + PV++
Sbjct: 1368 SAHGVRTTTGSTREPTSSTFQETGPVSM 1395



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 171/889 (19%), Positives = 324/889 (36%), Gaps = 70/889 (7%)

Query: 999  APSRQKAGTSALKTPGKTDDA--KASEKGKAPLKGSSLQRSPSDAGKS------SGDEGK 1050
            AP+     T+A  T  +T     KASE   A   GS    +PS  G        SG E  
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT-TPSPTGSQTTIVSISGSEIT 66

Query: 1051 KPPSGIGRSTATSSFGF--KKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNA 1108
               +    +T  SS G      S  GS   ++++G+  T+ S T  +    +A+G ++  
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 1109 GRKTSLDGSQ-----NQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSID 1163
               TS + +      ++   V  V S+TT  Y +    + +ST+G        + + +I 
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 1164 SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES--VSLSGSPKSS 1221
             + +       ++   E T + +  S   T +    E    +   SE+  VS +GS  + 
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 1222 PTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS--SVMPSPS 1279
             T+ S   A       +   + A     +   A   G   +A +T G + +  S M S +
Sbjct: 247  STAGSETTAASTEDSET---NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 1280 TTLARQG----SLESPSSGTGSMGSAGGLSGSSSPLFNKPSDL-TTDVISLSHSLASSPA 1334
            T  +  G     + + SS   ++ +AG  +  +S + ++ + + TT   + + S+  S  
Sbjct: 304  TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTH 1394
            S  S T+G     A+   S   +  T   ++ T   T SE+  + ++     S  TT   
Sbjct: 364  STDS-TTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITD----SETTTTCT 418

Query: 1395 EVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQD 1454
            E   +   + +V  T + S +    T+       T ++     E          T     
Sbjct: 419  EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478

Query: 1455 TGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDD 1514
            TG+++   S + + ++           + T  S+      +     ++  + S       
Sbjct: 479  TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVST 538

Query: 1515 SQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKL 1574
            +   GS T+       +S +G    +     GS ++ VS+T      AE    S +    
Sbjct: 539  T---GSETT------TVSTTG-LETTTTSTEGSEMTTVSTTG-----AETTTDSTEGSGT 583

Query: 1575 RRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELI----EL 1630
                 A  E     T+         A  E +  + TG   S T TA    SE      E 
Sbjct: 584  TAASTAGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEG 640

Query: 1631 RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 1690
             ET  +    +     +  G+        + +       + +VS+  S T+ S+ GSG  
Sbjct: 641  SETTTVSTTDSETTMVSTTGS-------ERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 1750
              S    +   V++ GSE  ++  +  G + +T   +        T+ S   +       
Sbjct: 694  TVSITGSETTKVSTTGSETTTTSTE--GSEITTASITGSETTTASTEGSETTTAST--EG 749

Query: 1751 GDCGSASMKPSQSASAICECTEAEAEIIL----QLKSELREKELKLTDIRLEALSSAHHL 1806
             +  SAS   S++ +A    +E     I+     + S +  +  K++    +  +     
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 1807 DQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSS 1855
             +   A         +  A ++ + A T  +   T   +E S +T++S+
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score =  104 bits (259), Expect = 1e-21
 Identities = 245/1206 (20%), Positives = 436/1206 (36%), Gaps = 142/1206 (11%)

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEG 373
            T   P A +  + +++    + ++ +K S T+T  T    +T  SPT S   +   +S  
Sbjct: 5    TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI-VSISGS 63

Query: 374  VKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
              T  S   S         + T         +  S  G +    S +G      S + S 
Sbjct: 64   EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 434  GSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
             +TNS+   S       AGS+  +                  + V +E       D  T 
Sbjct: 124  TTTNSTTS-SETTVTSTAGSETTT-----------------VSTVGSETTTAYTADSETT 165

Query: 494  MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTAS 548
             A    S++ ++   GS       E++ PS++G     +   GS+  TV  T S  +TAS
Sbjct: 166  AASTTGSEMTTVFTAGS-------ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218

Query: 549  KESEK--FRTTKGSPSQSLS---KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVA- 602
                +    +T GS +  +S      T+  A + +  A  E  E   A    S T T + 
Sbjct: 219  TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278

Query: 603  ---QSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYR-AHSENEGTALPSADSCTSPTKM 658
               +++  ST      +           +T+ P   + + + +E T + +A S T     
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 659  DLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFD 718
              S + T        +G +  T  +   +   D     E T +S  G++ + ++ E +  
Sbjct: 339  VGSETTTV-----STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 719  STVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSR 778
            +TV+T  +  T  ++T   T  T   G                       S       + 
Sbjct: 394  TTVSTTGSETTTVSITDSETTTTCTEG-----------------------SEMTAVSTTV 430

Query: 779  FMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINS 838
            F  TT     +   + + S  + +  ++   + ++    G         G    T   N+
Sbjct: 431  FETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTAS-NT 489

Query: 839  GYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIS 898
            G  T     + + +     + + +  +   G    TV  +  ++++  ++G   T   +S
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT--TVS 547

Query: 899  TDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAG 958
            T  L TT++ +  S +T  S    +  TDS + S T                  +   AG
Sbjct: 548  TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT-----------------TAASTAG 590

Query: 959  GKWKTVSSGLPED-PEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD 1017
             +  TVS+   E+         + S S TGS     S      +      S   T   TD
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 1018 DAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSGIGRSTAT-SSFGFKKPS 1071
                SE       GS     S + S +    ++G E      G G +T + +     K S
Sbjct: 651  ----SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVS 706

Query: 1072 GVGSSAMITSS-GATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSK 1130
              GS    TS+ G+ IT+ S T  +   ++  G ++      S +GS+         S+ 
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT---ASTEGSET-------TSAS 756

Query: 1131 TTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDS---NVSSKSAGATT--SKLREPTKIG 1185
            TT    +    + S T+     G   +  S+I S    VS+ S+  TT  ++  E T   
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1186 SGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIAS 1245
            +  S   TV+    E    + + SE+ + + +  S  T+AS  G++            AS
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE---------TTTAS 867

Query: 1246 PTFRRLFGAKAGGKSASAPNTEG--VKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGG 1303
                    A   G   +  +TEG    ++S   S +TT + +GS  +  S TGS  +   
Sbjct: 868  TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 1304 LSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY 1363
              GS +   +      T V +      +  A     T+   + +   ++S+AGS+ T   
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT-- 985

Query: 1364 QSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPK 1423
             S     T++ SI+      GS +   + T    + +  TG+  +T++ +   +  T+  
Sbjct: 986  VSTAGSETTTASIE------GSETTTVSSTGSETTTVSTTGT-ETTITSTEGSETTTVTT 1038

Query: 1424 KG-----LRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFS 1478
             G     +  T S       EG E     +TG    T + + L   + +S+S +G    S
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTVSTSGSGTTTAS 1097

Query: 1479 NLVSPT 1484
               S T
Sbjct: 1098 TAGSET 1103



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 253/1247 (20%), Positives = 449/1247 (36%), Gaps = 139/1247 (11%)

Query: 345  STMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPS 404
            +T ++   S T T  T  S+      +    TA S   S   K     + T +      +
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253

Query: 405  SGPS-DGGKDDDAFSESGEME-----GFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSN 458
            +  S +  + + AF+E  +       GF +   +  +T S P ++  +      +  +  
Sbjct: 254  TAASTEDSETNTAFTEDSKTTTASTTGFET--TAASTTGSEPTMASTMGSETTMASTIGP 311

Query: 459  KKSLLQPKEKE--------EKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGS 510
            + + +     E         +    + V +E          T  A    S+ ++    GS
Sbjct: 312  ETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGS 371

Query: 511  KTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
            +TT A  E    +++     GS+  TV  T S  +T S    +  TT    S+  +   T
Sbjct: 372  ETTTASTEGSETTTASTE--GSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT 429

Query: 571  MEKASASSCP------APLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSH 624
            + + + +S        A     E   AS  GS T TV  ++G  T        +    S+
Sbjct: 430  VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVT-TAGSETKTAYTTGSETTTASN 488

Query: 625  PNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMR 684
                T   F   + +    T   S  +  S T  +++   T       +S    ET  + 
Sbjct: 489  TGLETTTVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS 547

Query: 685  TVKNIADLRQNLEETMSSLRG---TQISHSTLETTFDST-----------------VTTE 724
            T          LE T +S  G   T +S +  ETT DST                 V+T 
Sbjct: 548  TT--------GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 725  VNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMY-TT 783
             +  T  +     T      G          + +  A    S T+    TD    M  TT
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 784  PLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKS---LRTDDINSGY 840
               R   S  G  S+        S+  +S+E   G   +   I G     + T    +  
Sbjct: 660  GSERTITSTEG--SETTTVSATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTT 714

Query: 841  MTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTD 900
             +  G  + T S+     T  S +    G    T   +  + +S+ ++G   T  + ++ 
Sbjct: 715  TSTEGSEITTASITGSETTTASTE----GSETTTASTEGSETTSASTTGSETTTASTTSS 770

Query: 901  DLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGK 960
            +    S + S + +       T   + +  + TT  T +S   +        +     G 
Sbjct: 771  ETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAG- 829

Query: 961  WKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG---APSRQKAGTSALKTPGK-- 1015
                S  +P     AG + + + S  GS     S +G      S + + T+   T G   
Sbjct: 830  ----SETIPAST--AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883

Query: 1016 -TDDAKASEKGKAPLKGSSLQRSPSDAGK-----SSGDEGKKPPSGIGRSTATSSFGFKK 1069
             T   + SE      +GS    + ++  +     ++G E     +    +T  S+ G + 
Sbjct: 884  TTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943

Query: 1070 P--SGVGSSAMITSSGATITSGSATLGKIPKSAAIGGK-----SNAGRKT---SLDGSQN 1119
               S  GS  +  S+  + T+   T+G    +A+  G      S AG +T   S++GS+ 
Sbjct: 944  TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 1120 QDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLR 1179
                V    S+TT    +    + +ST G        S T+++ +  S  +A  TT    
Sbjct: 1004 T--TVSSTGSETTTVSTTGTETTITSTEG--------SETTTVTTAGSETTAVYTTGS-- 1051

Query: 1180 EPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQ--PG 1237
            E T   +  S   TV+ T  E    + +D E+ ++S S  S  T+AS  G++       G
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG-SGTTTASTAGSETTTVYITG 1110

Query: 1238 SKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMP--SPSTTLARQGSLESPSSGT 1295
            SK    ++        +    ++ +A +T G + ++V    S +TT++  GS  + SS  
Sbjct: 1111 SKTTTASTEGSEATTVSTTSSETTTA-STTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1296 GSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSA 1355
            GS  +     GS +   +     TT   +      ++  S     +     +   + SSA
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1229

Query: 1356 GSK--------------DTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLM 1401
            GS+               T S +   +  T SE+  + ++  G+ +  TT +     L  
Sbjct: 1230 GSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK 1289

Query: 1402 RTG-SVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEW---LRSHSTGG--LQDT 1455
             T  S++   +  M   R T    G R T SS       G ++     SH+  G  L  +
Sbjct: 1290 ATDVSIQPITNTPMSGTRTT----GTRLTASS-SVTMAPGMDFTASAASHTVPGIVLNTS 1344

Query: 1456 GNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSI 1502
            G  +  +  S+ +S+   +    +   PT+ S F   GP  M +N++
Sbjct: 1345 GLGTSTMGASSTTSAHGVRTTTGSTREPTS-STFQETGPVSMGTNTV 1390



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 218/1205 (18%), Positives = 416/1205 (34%), Gaps = 79/1205 (6%)

Query: 225  LAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKP 284
            + A   T ++ +G  T+   PT   G      + S S++   S     + + +S      
Sbjct: 30   IKASETTTASTAGSETTTPSPT---GSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTT 86

Query: 285  PNYANGNEKDSSKGPQSSSGVN--------GNVQPPSTAGQPPASAIPSPSASKPWRSKS 336
                 G+E   S     ++ V+         +     T      S+  + +++    + +
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 337  MNVKHSATSTMLTVKQSSTATSPTPSS-DRLKPPVSEGVKTAPSGQKSMLEKFKLVNART 395
            ++   S T+T  T    +TA S T S    +    SE +  + +G ++           T
Sbjct: 147  VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSET-------TTVST 199

Query: 396  ALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKN 455
            A       S+  S+      A SE+       S      +  S   VS   +   A S  
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTE 259

Query: 456  LSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAA 515
             S   +      K           T       +  +      +T+  +++ P+ +K + A
Sbjct: 260  DSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA 319

Query: 516  KKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
              E     ++G         GS+  TV  T S  +TAS    +  T   + S++     T
Sbjct: 320  SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETT----T 375

Query: 571  MEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGN---GAVQLPQQQQHSHPNT 627
                 + +  A  EG EA   S +GS T TV+ +  ++T     G+             T
Sbjct: 376  ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 628  ATV--APFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRT 685
            A+   +     + S++E T   +  S T+      S +KTA     E +          T
Sbjct: 436  ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 686  VKNIAD-----LRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPM 740
            V  I         +  E T  S  G++++  + E + ++TV+T  +  T  + T   T  
Sbjct: 496  VFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT 555

Query: 741  TWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQID 800
            T   G     +    A +       SGT+            +T       +   +     
Sbjct: 556  TSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS 615

Query: 801  MSEKASSDLDMSS-EVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRS----LNR 855
             S   S     S+   +     ++G        TD   +   T G     T +       
Sbjct: 616  ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTT 675

Query: 856  IPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNIT 915
            +  T +   +   G    TV     + +   ++G   T  +    ++ T S   S +   
Sbjct: 676  VSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735

Query: 916  VPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKA 975
                  T   +     +T+  T  S            +     G   T++S +  +  K 
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 976  GQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQ 1035
               +S   +         +++    S   + T+ + T G ++   AS  G      +S +
Sbjct: 796  STASSKMTTVFTE-----NSETTIASTTASETTTVSTAG-SETIPASTAGSETTTTTSTE 849

Query: 1036 RSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKP--SGVGSSAMITSSGATITSGSATL 1093
             S +    + G E     +    +T  ++ G +    S  GS    TS+  + T+ ++T 
Sbjct: 850  GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909

Query: 1094 GKIPKSAAIGGK-----SNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSG 1148
            G    + +  G      S  G +T+   ++  +   +  +   T+   +      S T+ 
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA----EGSETTT 965

Query: 1149 IPGRGGHRSSTSSIDSN---VSSKSAGATTSKLR--EPTKIGSGRSSPVTVNQTDKEKEK 1203
            +   G   ++ S+  S    VS+  +  TT+ +   E T + S  S   TV+ T  E   
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 1204 VAVSDSES--VSLSGSP---------KSSPTSASACGAQGLRQPGSKYPDIASPTFRRLF 1252
             +   SE+  V+ +GS          +++ TS        +   GS+    AS       
Sbjct: 1026 TSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSE-TTTASTADLETT 1084

Query: 1253 GAKAGGKSASAPNTEGVKSSSVM--PSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSP 1310
                 G   +  +T G ++++V    S +TT + +GS  +  S T S  +    +GS   
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144

Query: 1311 LFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLH 1370
                    TT V ++     +S A+    T+     +   ++S+AGS+ T +  + +   
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETT 1204

Query: 1371 TSSES 1375
            T+S S
Sbjct: 1205 TASTS 1209



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 171/889 (19%), Positives = 324/889 (36%), Gaps = 70/889 (7%)

Query: 999  APSRQKAGTSALKTPGKTDDA--KASEKGKAPLKGSSLQRSPSDAGKS------SGDEGK 1050
            AP+     T+A  T  +T     KASE   A   GS    +PS  G        SG E  
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT-TPSPTGSQTTIVSISGSEIT 66

Query: 1051 KPPSGIGRSTATSSFGF--KKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNA 1108
               +    +T  SS G      S  GS   ++++G+  T+ S T  +    +A+G ++  
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 1109 GRKTSLDGSQ-----NQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSID 1163
               TS + +      ++   V  V S+TT  Y +    + +ST+G        + + +I 
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 1164 SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES--VSLSGSPKSS 1221
             + +       ++   E T + +  S   T +    E    +   SE+  VS +GS  + 
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 1222 PTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS--SVMPSPS 1279
             T+ S   A       +   + A     +   A   G   +A +T G + +  S M S +
Sbjct: 247  STAGSETTAASTEDSET---NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 1280 TTLARQG----SLESPSSGTGSMGSAGGLSGSSSPLFNKPSDL-TTDVISLSHSLASSPA 1334
            T  +  G     + + SS   ++ +AG  +  +S + ++ + + TT   + + S+  S  
Sbjct: 304  TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTH 1394
            S  S T+G     A+   S   +  T   ++ T   T SE+  + ++     S  TT   
Sbjct: 364  STDS-TTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITD----SETTTTCT 418

Query: 1395 EVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQD 1454
            E   +   + +V  T + S +    T+       T ++     E          T     
Sbjct: 419  EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478

Query: 1455 TGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDD 1514
            TG+++   S + + ++           + T  S+      +     ++  + S       
Sbjct: 479  TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVST 538

Query: 1515 SQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKL 1574
            +   GS T+       +S +G    +     GS ++ VS+T      AE    S +    
Sbjct: 539  T---GSETT------TVSTTG-LETTTTSTEGSEMTTVSTTG-----AETTTDSTEGSGT 583

Query: 1575 RRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELI----EL 1630
                 A  E     T+         A  E +  + TG   S T TA    SE      E 
Sbjct: 584  TAASTAGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEG 640

Query: 1631 RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 1690
             ET  +    +     +  G+        + +       + +VS+  S T+ S+ GSG  
Sbjct: 641  SETTTVSTTDSETTMVSTTGS-------ERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 1750
              S    +   V++ GSE  ++  +  G + +T   +        T+ S   +       
Sbjct: 694  TVSITGSETTKVSTTGSETTTTSTE--GSEITTASITGSETTTASTEGSETTTAST--EG 749

Query: 1751 GDCGSASMKPSQSASAICECTEAEAEIIL----QLKSELREKELKLTDIRLEALSSAHHL 1806
             +  SAS   S++ +A    +E     I+     + S +  +  K++    +  +     
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 1807 DQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSS 1855
             +   A         +  A ++ + A T  +   T   +E S +T++S+
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score =  104 bits (259), Expect = 1e-21
 Identities = 245/1206 (20%), Positives = 436/1206 (36%), Gaps = 142/1206 (11%)

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEG 373
            T   P A +  + +++    + ++ +K S T+T  T    +T  SPT S   +   +S  
Sbjct: 5    TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI-VSISGS 63

Query: 374  VKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
              T  S   S         + T         +  S  G +    S +G      S + S 
Sbjct: 64   EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 434  GSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
             +TNS+   S       AGS+  +                  + V +E       D  T 
Sbjct: 124  TTTNSTTS-SETTVTSTAGSETTT-----------------VSTVGSETTTAYTADSETT 165

Query: 494  MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTAS 548
             A    S++ ++   GS       E++ PS++G     +   GS+  TV  T S  +TAS
Sbjct: 166  AASTTGSEMTTVFTAGS-------ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218

Query: 549  KESEK--FRTTKGSPSQSLS---KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVA- 602
                +    +T GS +  +S      T+  A + +  A  E  E   A    S T T + 
Sbjct: 219  TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278

Query: 603  ---QSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYR-AHSENEGTALPSADSCTSPTKM 658
               +++  ST      +           +T+ P   + + + +E T + +A S T     
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 659  DLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFD 718
              S + T        +G +  T  +   +   D     E T +S  G++ + ++ E +  
Sbjct: 339  VGSETTTV-----STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 719  STVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSR 778
            +TV+T  +  T  ++T   T  T   G                       S       + 
Sbjct: 394  TTVSTTGSETTTVSITDSETTTTCTEG-----------------------SEMTAVSTTV 430

Query: 779  FMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINS 838
            F  TT     +   + + S  + +  ++   + ++    G         G    T   N+
Sbjct: 431  FETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTAS-NT 489

Query: 839  GYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIS 898
            G  T     + + +     + + +  +   G    TV  +  ++++  ++G   T   +S
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT--TVS 547

Query: 899  TDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAG 958
            T  L TT++ +  S +T  S    +  TDS + S T                  +   AG
Sbjct: 548  TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT-----------------TAASTAG 590

Query: 959  GKWKTVSSGLPED-PEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD 1017
             +  TVS+   E+         + S S TGS     S      +      S   T   TD
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 1018 DAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSGIGRSTAT-SSFGFKKPS 1071
                SE       GS     S + S +    ++G E      G G +T + +     K S
Sbjct: 651  ----SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVS 706

Query: 1072 GVGSSAMITSS-GATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSK 1130
              GS    TS+ G+ IT+ S T  +   ++  G ++      S +GS+         S+ 
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT---ASTEGSET-------TSAS 756

Query: 1131 TTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDS---NVSSKSAGATT--SKLREPTKIG 1185
            TT    +    + S T+     G   +  S+I S    VS+ S+  TT  ++  E T   
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1186 SGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIAS 1245
            +  S   TV+    E    + + SE+ + + +  S  T+AS  G++            AS
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE---------TTTAS 867

Query: 1246 PTFRRLFGAKAGGKSASAPNTEG--VKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGG 1303
                    A   G   +  +TEG    ++S   S +TT + +GS  +  S TGS  +   
Sbjct: 868  TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 1304 LSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY 1363
              GS +   +      T V +      +  A     T+   + +   ++S+AGS+ T   
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT-- 985

Query: 1364 QSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPK 1423
             S     T++ SI+      GS +   + T    + +  TG+  +T++ +   +  T+  
Sbjct: 986  VSTAGSETTTASIE------GSETTTVSSTGSETTTVSTTGT-ETTITSTEGSETTTVTT 1038

Query: 1424 KG-----LRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFS 1478
             G     +  T S       EG E     +TG    T + + L   + +S+S +G    S
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTVSTSGSGTTTAS 1097

Query: 1479 NLVSPT 1484
               S T
Sbjct: 1098 TAGSET 1103



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 253/1247 (20%), Positives = 449/1247 (36%), Gaps = 139/1247 (11%)

Query: 345  STMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPS 404
            +T ++   S T T  T  S+      +    TA S   S   K     + T +      +
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253

Query: 405  SGPS-DGGKDDDAFSESGEME-----GFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSN 458
            +  S +  + + AF+E  +       GF +   +  +T S P ++  +      +  +  
Sbjct: 254  TAASTEDSETNTAFTEDSKTTTASTTGFET--TAASTTGSEPTMASTMGSETTMASTIGP 311

Query: 459  KKSLLQPKEKE--------EKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGS 510
            + + +     E         +    + V +E          T  A    S+ ++    GS
Sbjct: 312  ETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGS 371

Query: 511  KTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
            +TT A  E    +++     GS+  TV  T S  +T S    +  TT    S+  +   T
Sbjct: 372  ETTTASTEGSETTTASTE--GSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT 429

Query: 571  MEKASASSCP------APLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSH 624
            + + + +S        A     E   AS  GS T TV  ++G  T        +    S+
Sbjct: 430  VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVT-TAGSETKTAYTTGSETTTASN 488

Query: 625  PNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMR 684
                T   F   + +    T   S  +  S T  +++   T       +S    ET  + 
Sbjct: 489  TGLETTTVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS 547

Query: 685  TVKNIADLRQNLEETMSSLRG---TQISHSTLETTFDST-----------------VTTE 724
            T          LE T +S  G   T +S +  ETT DST                 V+T 
Sbjct: 548  TT--------GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 725  VNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMY-TT 783
             +  T  +     T      G          + +  A    S T+    TD    M  TT
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 784  PLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKS---LRTDDINSGY 840
               R   S  G  S+        S+  +S+E   G   +   I G     + T    +  
Sbjct: 660  GSERTITSTEG--SETTTVSATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTT 714

Query: 841  MTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTD 900
             +  G  + T S+     T  S +    G    T   +  + +S+ ++G   T  + ++ 
Sbjct: 715  TSTEGSEITTASITGSETTTASTE----GSETTTASTEGSETTSASTTGSETTTASTTSS 770

Query: 901  DLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGK 960
            +    S + S + +       T   + +  + TT  T +S   +        +     G 
Sbjct: 771  ETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAG- 829

Query: 961  WKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG---APSRQKAGTSALKTPGK-- 1015
                S  +P     AG + + + S  GS     S +G      S + + T+   T G   
Sbjct: 830  ----SETIPAST--AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883

Query: 1016 -TDDAKASEKGKAPLKGSSLQRSPSDAGK-----SSGDEGKKPPSGIGRSTATSSFGFKK 1069
             T   + SE      +GS    + ++  +     ++G E     +    +T  S+ G + 
Sbjct: 884  TTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943

Query: 1070 P--SGVGSSAMITSSGATITSGSATLGKIPKSAAIGGK-----SNAGRKT---SLDGSQN 1119
               S  GS  +  S+  + T+   T+G    +A+  G      S AG +T   S++GS+ 
Sbjct: 944  TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 1120 QDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLR 1179
                V    S+TT    +    + +ST G        S T+++ +  S  +A  TT    
Sbjct: 1004 T--TVSSTGSETTTVSTTGTETTITSTEG--------SETTTVTTAGSETTAVYTTGS-- 1051

Query: 1180 EPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQ--PG 1237
            E T   +  S   TV+ T  E    + +D E+ ++S S  S  T+AS  G++       G
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG-SGTTTASTAGSETTTVYITG 1110

Query: 1238 SKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMP--SPSTTLARQGSLESPSSGT 1295
            SK    ++        +    ++ +A +T G + ++V    S +TT++  GS  + SS  
Sbjct: 1111 SKTTTASTEGSEATTVSTTSSETTTA-STTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1296 GSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSA 1355
            GS  +     GS +   +     TT   +      ++  S     +     +   + SSA
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1229

Query: 1356 GSK--------------DTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLM 1401
            GS+               T S +   +  T SE+  + ++  G+ +  TT +     L  
Sbjct: 1230 GSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK 1289

Query: 1402 RTG-SVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEW---LRSHSTGG--LQDT 1455
             T  S++   +  M   R T    G R T SS       G ++     SH+  G  L  +
Sbjct: 1290 ATDVSIQPITNTPMSGTRTT----GTRLTASS-SVTMAPGMDFTASAASHTVPGIVLNTS 1344

Query: 1456 GNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSI 1502
            G  +  +  S+ +S+   +    +   PT+ S F   GP  M +N++
Sbjct: 1345 GLGTSTMGASSTTSAHGVRTTTGSTREPTS-STFQETGPVSMGTNTV 1390



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 218/1205 (18%), Positives = 416/1205 (34%), Gaps = 79/1205 (6%)

Query: 225  LAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKP 284
            + A   T ++ +G  T+   PT   G      + S S++   S     + + +S      
Sbjct: 30   IKASETTTASTAGSETTTPSPT---GSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTT 86

Query: 285  PNYANGNEKDSSKGPQSSSGVN--------GNVQPPSTAGQPPASAIPSPSASKPWRSKS 336
                 G+E   S     ++ V+         +     T      S+  + +++    + +
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 337  MNVKHSATSTMLTVKQSSTATSPTPSS-DRLKPPVSEGVKTAPSGQKSMLEKFKLVNART 395
            ++   S T+T  T    +TA S T S    +    SE +  + +G ++           T
Sbjct: 147  VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSET-------TTVST 199

Query: 396  ALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKN 455
            A       S+  S+      A SE+       S      +  S   VS   +   A S  
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTE 259

Query: 456  LSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAA 515
             S   +      K           T       +  +      +T+  +++ P+ +K + A
Sbjct: 260  DSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA 319

Query: 516  KKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
              E     ++G         GS+  TV  T S  +TAS    +  T   + S++     T
Sbjct: 320  SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETT----T 375

Query: 571  MEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGN---GAVQLPQQQQHSHPNT 627
                 + +  A  EG EA   S +GS T TV+ +  ++T     G+             T
Sbjct: 376  ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 628  ATV--APFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRT 685
            A+   +     + S++E T   +  S T+      S +KTA     E +          T
Sbjct: 436  ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 686  VKNIAD-----LRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPM 740
            V  I         +  E T  S  G++++  + E + ++TV+T  +  T  + T   T  
Sbjct: 496  VFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT 555

Query: 741  TWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQID 800
            T   G     +    A +       SGT+            +T       +   +     
Sbjct: 556  TSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS 615

Query: 801  MSEKASSDLDMSS-EVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRS----LNR 855
             S   S     S+   +     ++G        TD   +   T G     T +       
Sbjct: 616  ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTT 675

Query: 856  IPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNIT 915
            +  T +   +   G    TV     + +   ++G   T  +    ++ T S   S +   
Sbjct: 676  VSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735

Query: 916  VPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKA 975
                  T   +     +T+  T  S            +     G   T++S +  +  K 
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 976  GQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQ 1035
               +S   +         +++    S   + T+ + T G ++   AS  G      +S +
Sbjct: 796  STASSKMTTVFTE-----NSETTIASTTASETTTVSTAG-SETIPASTAGSETTTTTSTE 849

Query: 1036 RSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKP--SGVGSSAMITSSGATITSGSATL 1093
             S +    + G E     +    +T  ++ G +    S  GS    TS+  + T+ ++T 
Sbjct: 850  GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909

Query: 1094 GKIPKSAAIGGK-----SNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSG 1148
            G    + +  G      S  G +T+   ++  +   +  +   T+   +      S T+ 
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA----EGSETTT 965

Query: 1149 IPGRGGHRSSTSSIDSN---VSSKSAGATTSKLR--EPTKIGSGRSSPVTVNQTDKEKEK 1203
            +   G   ++ S+  S    VS+  +  TT+ +   E T + S  S   TV+ T  E   
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 1204 VAVSDSES--VSLSGSP---------KSSPTSASACGAQGLRQPGSKYPDIASPTFRRLF 1252
             +   SE+  V+ +GS          +++ TS        +   GS+    AS       
Sbjct: 1026 TSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSE-TTTASTADLETT 1084

Query: 1253 GAKAGGKSASAPNTEGVKSSSVM--PSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSP 1310
                 G   +  +T G ++++V    S +TT + +GS  +  S T S  +    +GS   
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144

Query: 1311 LFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLH 1370
                    TT V ++     +S A+    T+     +   ++S+AGS+ T +  + +   
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETT 1204

Query: 1371 TSSES 1375
            T+S S
Sbjct: 1205 TASTS 1209



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 171/889 (19%), Positives = 324/889 (36%), Gaps = 70/889 (7%)

Query: 999  APSRQKAGTSALKTPGKTDDA--KASEKGKAPLKGSSLQRSPSDAGKS------SGDEGK 1050
            AP+     T+A  T  +T     KASE   A   GS    +PS  G        SG E  
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT-TPSPTGSQTTIVSISGSEIT 66

Query: 1051 KPPSGIGRSTATSSFGF--KKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNA 1108
               +    +T  SS G      S  GS   ++++G+  T+ S T  +    +A+G ++  
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 1109 GRKTSLDGSQ-----NQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSID 1163
               TS + +      ++   V  V S+TT  Y +    + +ST+G        + + +I 
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 1164 SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES--VSLSGSPKSS 1221
             + +       ++   E T + +  S   T +    E    +   SE+  VS +GS  + 
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 1222 PTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS--SVMPSPS 1279
             T+ S   A       +   + A     +   A   G   +A +T G + +  S M S +
Sbjct: 247  STAGSETTAASTEDSET---NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 1280 TTLARQG----SLESPSSGTGSMGSAGGLSGSSSPLFNKPSDL-TTDVISLSHSLASSPA 1334
            T  +  G     + + SS   ++ +AG  +  +S + ++ + + TT   + + S+  S  
Sbjct: 304  TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTH 1394
            S  S T+G     A+   S   +  T   ++ T   T SE+  + ++     S  TT   
Sbjct: 364  STDS-TTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITD----SETTTTCT 418

Query: 1395 EVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQD 1454
            E   +   + +V  T + S +    T+       T ++     E          T     
Sbjct: 419  EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478

Query: 1455 TGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDD 1514
            TG+++   S + + ++           + T  S+      +     ++  + S       
Sbjct: 479  TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVST 538

Query: 1515 SQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKL 1574
            +   GS T+       +S +G    +     GS ++ VS+T      AE    S +    
Sbjct: 539  T---GSETT------TVSTTG-LETTTTSTEGSEMTTVSTTG-----AETTTDSTEGSGT 583

Query: 1575 RRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELI----EL 1630
                 A  E     T+         A  E +  + TG   S T TA    SE      E 
Sbjct: 584  TAASTAGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEG 640

Query: 1631 RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 1690
             ET  +    +     +  G+        + +       + +VS+  S T+ S+ GSG  
Sbjct: 641  SETTTVSTTDSETTMVSTTGS-------ERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 1750
              S    +   V++ GSE  ++  +  G + +T   +        T+ S   +       
Sbjct: 694  TVSITGSETTKVSTTGSETTTTSTE--GSEITTASITGSETTTASTEGSETTTAST--EG 749

Query: 1751 GDCGSASMKPSQSASAICECTEAEAEIIL----QLKSELREKELKLTDIRLEALSSAHHL 1806
             +  SAS   S++ +A    +E     I+     + S +  +  K++    +  +     
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 1807 DQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSS 1855
             +   A         +  A ++ + A T  +   T   +E S +T++S+
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score =  104 bits (259), Expect = 1e-21
 Identities = 235/1223 (19%), Positives = 440/1223 (35%), Gaps = 147/1223 (12%)

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEG 373
            TA    +    +P+A     + + +   S T+T+L +K S T T+ T  S+   P     
Sbjct: 18   TASSMSSETTVAPAAGS--NTTTASTTGSETTTIL-IKASETTTASTAGSETTTP----- 69

Query: 374  VKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGE------MEGFN 427
               +P+G ++ +         T            S  G ++   S +G       M G  
Sbjct: 70   ---SPTGSQTTIVSISGSEITTT-----------STAGSENTTVSSAGSGTTTASMAGSE 115

Query: 428  SGLNSGGSTNSSPKVS--PKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCT---EK 482
            S +++ GS  ++  ++          GS+  +N  +  +         +   V T   E 
Sbjct: 116  STISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSET 175

Query: 483  PVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG-----IPKPGSKVPTV 537
                  D  T  A    S++ ++   GS+T       + PS++G     +   GS+  TV
Sbjct: 176  TTAYTADSETTAASTTGSEMTTVFTAGSET-------ITPSTAGSETTTVSTAGSETTTV 228

Query: 538  KQTISPGSTASKESEKFR--TTKGSPSQSLS---KPITMEKASASSCPAPLEGREAGQAS 592
              T S  +TAS    +    +T GS +  +S      T+  A + +  A  E  E   A 
Sbjct: 229  STTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAF 288

Query: 593  PSGSCTMTVA----QSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHS-ENEGTALP 647
               S T T +    +++  ST      +           +T+ P   +  +  +E T + 
Sbjct: 289  TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVF 348

Query: 648  SADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQ 707
            +A S T       S + T        +G +  T  +   +   D     E T +S  G++
Sbjct: 349  AAGSETIRASTVGSETTTVST-----TGSETTTASIMGSETSTDSTTGSETTTASTEGSE 403

Query: 708  ISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSG 767
             + ++ E +  +TV+T  +  T  ++T   T  T   G                      
Sbjct: 404  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG---------------------- 441

Query: 768  TSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDIL 827
             S       + F  TT     +   + + S  + +  ++   + ++    G         
Sbjct: 442  -SEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTT 500

Query: 828  GKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVS 887
            G    T   N+G  T     + + +     + + +  +   G    TV  +  ++++  +
Sbjct: 501  GSETTTAS-NTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVST 559

Query: 888  SGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRS------------TTD 935
            +G   T   +ST  L TT++ +  S +T  S    +  TDS + S            TT 
Sbjct: 560  TGSETT--TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 617

Query: 936  ETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLS------------V 983
             T DS        +   +     G   T +S    +   A  + S +            V
Sbjct: 618  STADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMV 677

Query: 984  SQTGSWRRGMSAQGGAPSRQKAGTS--ALKTPGK---TDDAKASEKGKAPLKGS-----S 1033
            S TGS R   S +G   +   A  S   + T G    T     SE  K    GS     S
Sbjct: 678  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 737

Query: 1034 LQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATL 1093
             + S       +G E     +    +T  S+ G +  S   + +  T+  A+ TS   T+
Sbjct: 738  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT--ASTTSSETTM 795

Query: 1094 GKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRG 1153
              I  S      +     T +  + ++   V   +S+TT+   +    +  ST+G     
Sbjct: 796  ASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAG----- 850

Query: 1154 GHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVS 1213
                 + +I ++ +      TTS     T   S   S  T   T+  +   A +     +
Sbjct: 851  -----SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 905

Query: 1214 LSGSPKSSPTSASACGAQ--GLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKS 1271
             + +  S  T+ S  G++       GS+   + S T      A   G   +  +TEG + 
Sbjct: 906  TASTEGSETTTTSTEGSETTTASTEGSEITTV-STTGSETTTASTEGSETTTASTEGSEL 964

Query: 1272 SSVMP--SPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSL 1329
            ++V    S + T++ +GS  +  +  GS  +    +GS +   +     TT   S+  S 
Sbjct: 965  TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT-TASIEGSE 1023

Query: 1330 ASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGL 1389
             ++ +S  S T+        +S++   +  T +  S T+  T++ S    +   GS    
Sbjct: 1024 TTTVSSTGSETT-------TVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS-ETT 1075

Query: 1390 TTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHST 1449
            TT T   ++  + T    +T + +  L+  T+   G   T +S  A  E    ++    T
Sbjct: 1076 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS-TAGSETTTVYITGSKT 1134

Query: 1450 GGLQDTGNQSPLVSPSAMSSSAA 1472
                  G+++  VS ++  ++ A
Sbjct: 1135 TTASTEGSEATTVSTTSSETTTA 1157



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 253/1247 (20%), Positives = 449/1247 (36%), Gaps = 139/1247 (11%)

Query: 345  STMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPS 404
            +T ++   S T T  T  S+      +    TA S   S   K     + T +      +
Sbjct: 215  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 274

Query: 405  SGPS-DGGKDDDAFSESGEME-----GFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSN 458
            +  S +  + + AF+E  +       GF +   +  +T S P ++  +      +  +  
Sbjct: 275  TAASTEDSETNTAFTEDSKTTTASTTGFET--TAASTTGSEPTMASTMGSETTMASTIGP 332

Query: 459  KKSLLQPKEKE--------EKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGS 510
            + + +     E         +    + V +E          T  A    S+ ++    GS
Sbjct: 333  ETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGS 392

Query: 511  KTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
            +TT A  E    +++     GS+  TV  T S  +T S    +  TT    S+  +   T
Sbjct: 393  ETTTASTEGSETTTASTE--GSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT 450

Query: 571  MEKASASSCP------APLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSH 624
            + + + +S        A     E   AS  GS T TV  ++G  T        +    S+
Sbjct: 451  VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVT-TAGSETKTAYTTGSETTTASN 509

Query: 625  PNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMR 684
                T   F   + +    T   S  +  S T  +++   T       +S    ET  + 
Sbjct: 510  TGLETTTVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS 568

Query: 685  TVKNIADLRQNLEETMSSLRG---TQISHSTLETTFDST-----------------VTTE 724
            T          LE T +S  G   T +S +  ETT DST                 V+T 
Sbjct: 569  TT--------GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 620

Query: 725  VNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMY-TT 783
             +  T  +     T      G          + +  A    S T+    TD    M  TT
Sbjct: 621  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 680

Query: 784  PLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKS---LRTDDINSGY 840
               R   S  G  S+        S+  +S+E   G   +   I G     + T    +  
Sbjct: 681  GSERTITSTEG--SETTTVSATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTT 735

Query: 841  MTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTD 900
             +  G  + T S+     T  S +    G    T   +  + +S+ ++G   T  + ++ 
Sbjct: 736  TSTEGSEITTASITGSETTTASTE----GSETTTASTEGSETTSASTTGSETTTASTTSS 791

Query: 901  DLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGK 960
            +    S + S + +       T   + +  + TT  T +S   +        +     G 
Sbjct: 792  ETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAG- 850

Query: 961  WKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG---APSRQKAGTSALKTPGK-- 1015
                S  +P     AG + + + S  GS     S +G      S + + T+   T G   
Sbjct: 851  ----SETIPAST--AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 904

Query: 1016 -TDDAKASEKGKAPLKGSSLQRSPSDAGK-----SSGDEGKKPPSGIGRSTATSSFGFKK 1069
             T   + SE      +GS    + ++  +     ++G E     +    +T  S+ G + 
Sbjct: 905  TTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 964

Query: 1070 P--SGVGSSAMITSSGATITSGSATLGKIPKSAAIGGK-----SNAGRKT---SLDGSQN 1119
               S  GS  +  S+  + T+   T+G    +A+  G      S AG +T   S++GS+ 
Sbjct: 965  TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1024

Query: 1120 QDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLR 1179
                V    S+TT    +    + +ST G        S T+++ +  S  +A  TT    
Sbjct: 1025 T--TVSSTGSETTTVSTTGTETTITSTEG--------SETTTVTTAGSETTAVYTTGS-- 1072

Query: 1180 EPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQ--PG 1237
            E T   +  S   TV+ T  E    + +D E+ ++S S  S  T+AS  G++       G
Sbjct: 1073 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG-SGTTTASTAGSETTTVYITG 1131

Query: 1238 SKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMP--SPSTTLARQGSLESPSSGT 1295
            SK    ++        +    ++ +A +T G + ++V    S +TT++  GS  + SS  
Sbjct: 1132 SKTTTASTEGSEATTVSTTSSETTTA-STTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1190

Query: 1296 GSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSA 1355
            GS  +     GS +   +     TT   +      ++  S     +     +   + SSA
Sbjct: 1191 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1250

Query: 1356 GSK--------------DTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLM 1401
            GS+               T S +   +  T SE+  + ++  G+ +  TT +     L  
Sbjct: 1251 GSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK 1310

Query: 1402 RTG-SVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEW---LRSHSTGG--LQDT 1455
             T  S++   +  M   R T    G R T SS       G ++     SH+  G  L  +
Sbjct: 1311 ATDVSIQPITNTPMSGTRTT----GTRLTASS-SVTMAPGMDFTASAASHTVPGIVLNTS 1365

Query: 1456 GNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSI 1502
            G  +  +  S+ +S+   +    +   PT+ S F   GP  M +N++
Sbjct: 1366 GLGTSTMGASSTTSAHGVRTTTGSTREPTS-STFQETGPVSMGTNTV 1411



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 228/1232 (18%), Positives = 421/1232 (34%), Gaps = 84/1232 (6%)

Query: 213  SQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRL----PGPSRVPAAGSSSKVQGASN 268
            S+  T   M S      A  SN +  +T+  + T +       +    AGS +     + 
Sbjct: 14   SKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTG 73

Query: 269  LNRRSQSFNSIDKNKPPNYANGNEKDSSKGP-QSSSGVNGNVQPPSTAGQPPA------- 320
                  S +  +        + N   SS G   +++ + G+    STAG           
Sbjct: 74   SQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTTVSITGT 133

Query: 321  -----SAIPSPSASKPWRSKSMNVKHSATSTMLTVKQ--SSTATSPTPSSDRLKPPV--S 371
                 SA+ S + +    S    V  +A S   TV    S T T+ T  S+        S
Sbjct: 134  ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGS 193

Query: 372  EGVKTAPSGQKSMLEKF---KLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNS 428
            E      +G +++       +     TA       S+  S+      A SE+       S
Sbjct: 194  EMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGS 253

Query: 429  GLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEK 488
                  +  S   VS   +   A S   S   +      K           T       +
Sbjct: 254  ETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE 313

Query: 489  DQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG-----IPKPGSKVPTVKQTISP 543
              +      +T+  +++ P+ +K + A  E     ++G         GS+  TV  T S 
Sbjct: 314  PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSE 373

Query: 544  GSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQ 603
             +TAS    +  T   + S++     T     + +  A  EG EA   S +GS T TV+ 
Sbjct: 374  TTTASIMGSETSTDSTTGSETT----TASTEGSETTTASTEGSEATTVSTTGSETTTVSI 429

Query: 604  SSGQSTGN---GAVQLPQQQQHSHPNTATV--APFIYRAHSENEGTALPSADSCTSPTKM 658
            +  ++T     G+             TA+   +     + S++E T   +  S T+    
Sbjct: 430  TDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 489

Query: 659  DLSYSKTAKQCLEEISGEDPETRRMRTVKNIAD-----LRQNLEETMSSLRGTQISHSTL 713
              S +KTA     E +          TV  I         +  E T  S  G++++  + 
Sbjct: 490  AGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVST 549

Query: 714  ETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIH 773
            E + ++TV+T  +  T  + T   T  T   G     +    A +       SGT+    
Sbjct: 550  EGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAST 609

Query: 774  TDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSS-EVDVGGYMSDGDILGKSLR 832
                    +T       +   +      S   S     S+   +     ++G        
Sbjct: 610  AGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 669

Query: 833  TDDINSGYMTDGGLNLYTRS----LNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSS 888
            TD   +   T G     T +       +  T +   +   G    TV     + +   ++
Sbjct: 670  TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT 729

Query: 889  GLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPE 948
            G   T  +    ++ T S   S +         T   +     +T+  T  S        
Sbjct: 730  GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 789

Query: 949  EDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTS 1008
                +     G   T++S +  +  K    +S   +         +++    S   + T+
Sbjct: 790  SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTE-----NSETTIASTTASETT 844

Query: 1009 ALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFK 1068
             + T G ++   AS  G      +S + S +    + G E     +    +T  ++ G +
Sbjct: 845  TVSTAG-SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 903

Query: 1069 KP--SGVGSSAMITSSGATITSGSATLGKIPKSAAIGGK-----SNAGRKTSLDGSQNQD 1121
                S  GS    TS+  + T+ ++T G    + +  G      S  G +T+   ++  +
Sbjct: 904  TTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSE 963

Query: 1122 DVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSN---VSSKSAGATTSKL 1178
               +  +   T+   +      S T+ +   G   ++ S+  S    VS+  +  TT+ +
Sbjct: 964  LTTVSTTGSETITVSA----EGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASI 1019

Query: 1179 R--EPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES--VSLSGSP---------KSSPTSA 1225
               E T + S  S   TV+ T  E    +   SE+  V+ +GS          +++ TS 
Sbjct: 1020 EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST 1079

Query: 1226 SACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVM--PSPSTTLA 1283
                   +   GS+    AS            G   +  +T G ++++V    S +TT +
Sbjct: 1080 EGSETTTVSTTGSE-TTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAS 1138

Query: 1284 RQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGG 1343
             +GS  +  S T S  +    +GS           TT V ++     +S A+    T+  
Sbjct: 1139 TEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTS 1198

Query: 1344 LVWAANMSSSSAGSKDTPSYQSMTSLHTSSES 1375
               +   ++S+AGS+ T +  + +   T+S S
Sbjct: 1199 TEGSETTTASTAGSETTTASTAGSETTTASTS 1230



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 172/889 (19%), Positives = 325/889 (36%), Gaps = 70/889 (7%)

Query: 999  APSRQKAGTSALKTPGKTDDA--KASEKGKAPLKGSSLQRSPSDAGKS------SGDEGK 1050
            AP+     T+A  T  +T     KASE   A   GS    +PS  G        SG E  
Sbjct: 29   APAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT-TPSPTGSQTTIVSISGSEIT 87

Query: 1051 KPPSGIGRSTATSSFGF--KKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNA 1108
               +    +T  SS G      S  GS + I+++G+  T+ S T  +    +A+G ++  
Sbjct: 88   TTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETTT 147

Query: 1109 GRKTSLDGSQ-----NQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSID 1163
               TS + +      ++   V  V S+TT  Y +    + +ST+G        + + +I 
Sbjct: 148  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 207

Query: 1164 SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES--VSLSGSPKSS 1221
             + +       ++   E T + +  S   T +    E    +   SE+  VS +GS  + 
Sbjct: 208  PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 267

Query: 1222 PTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS--SVMPSPS 1279
             T+ S   A       +   + A     +   A   G   +A +T G + +  S M S +
Sbjct: 268  STAGSETTAASTEDSET---NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSET 324

Query: 1280 TTLARQG----SLESPSSGTGSMGSAGGLSGSSSPLFNKPSDL-TTDVISLSHSLASSPA 1334
            T  +  G     + + SS   ++ +AG  +  +S + ++ + + TT   + + S+  S  
Sbjct: 325  TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 384

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTH 1394
            S  S T+G     A+   S   +  T   ++ T   T SE+  + ++     S  TT   
Sbjct: 385  STDS-TTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITD----SETTTTCT 439

Query: 1395 EVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQD 1454
            E   +   + +V  T + S +    T+       T ++     E          T     
Sbjct: 440  EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 499

Query: 1455 TGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDD 1514
            TG+++   S + + ++           + T  S+      +     ++  + S       
Sbjct: 500  TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVST 559

Query: 1515 SQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKL 1574
            +   GS T+       +S +G    +     GS ++ VS+T      AE    S +    
Sbjct: 560  T---GSETT------TVSTTG-LETTTTSTEGSEMTTVSTTG-----AETTTDSTEGSGT 604

Query: 1575 RRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELI----EL 1630
                 A  E     T+         A  E +  + TG   S T TA    SE      E 
Sbjct: 605  TAASTAGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEG 661

Query: 1631 RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 1690
             ET  +    +     +  G+        + +       + +VS+  S T+ S+ GSG  
Sbjct: 662  SETTTVSTTDSETTMVSTTGS-------ERTITSTEGSETTTVSATGSETTVSTEGSGTT 714

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 1750
              S    +   V++ GSE  ++  +  G + +T   +        T+ S   +       
Sbjct: 715  TVSITGSETTKVSTTGSETTTTSTE--GSEITTASITGSETTTASTEGSETTTAST--EG 770

Query: 1751 GDCGSASMKPSQSASAICECTEAEAEIIL----QLKSELREKELKLTDIRLEALSSAHHL 1806
             +  SAS   S++ +A    +E     I+     + S +  +  K++    +  +     
Sbjct: 771  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 830

Query: 1807 DQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSS 1855
             +   A         +  A ++ + A T  +   T   +E S +T++S+
Sbjct: 831  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 879


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score =  104 bits (259), Expect = 1e-21
 Identities = 245/1206 (20%), Positives = 436/1206 (36%), Gaps = 142/1206 (11%)

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEG 373
            T   P A +  + +++    + ++ +K S T+T  T    +T  SPT S   +   +S  
Sbjct: 5    TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI-VSISGS 63

Query: 374  VKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
              T  S   S         + T         +  S  G +    S +G      S + S 
Sbjct: 64   EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 434  GSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
             +TNS+   S       AGS+  +                  + V +E       D  T 
Sbjct: 124  TTTNSTTS-SETTVTSTAGSETTT-----------------VSTVGSETTTAYTADSETT 165

Query: 494  MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTAS 548
             A    S++ ++   GS       E++ PS++G     +   GS+  TV  T S  +TAS
Sbjct: 166  AASTTGSEMTTVFTAGS-------ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218

Query: 549  KESEK--FRTTKGSPSQSLS---KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVA- 602
                +    +T GS +  +S      T+  A + +  A  E  E   A    S T T + 
Sbjct: 219  TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278

Query: 603  ---QSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYR-AHSENEGTALPSADSCTSPTKM 658
               +++  ST      +           +T+ P   + + + +E T + +A S T     
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 659  DLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFD 718
              S + T        +G +  T  +   +   D     E T +S  G++ + ++ E +  
Sbjct: 339  VGSETTTV-----STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 719  STVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSR 778
            +TV+T  +  T  ++T   T  T   G                       S       + 
Sbjct: 394  TTVSTTGSETTTVSITDSETTTTCTEG-----------------------SEMTAVSTTV 430

Query: 779  FMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINS 838
            F  TT     +   + + S  + +  ++   + ++    G         G    T   N+
Sbjct: 431  FETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTAS-NT 489

Query: 839  GYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIS 898
            G  T     + + +     + + +  +   G    TV  +  ++++  ++G   T   +S
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT--TVS 547

Query: 899  TDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAG 958
            T  L TT++ +  S +T  S    +  TDS + S T                  +   AG
Sbjct: 548  TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT-----------------TAASTAG 590

Query: 959  GKWKTVSSGLPED-PEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD 1017
             +  TVS+   E+         + S S TGS     S      +      S   T   TD
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 1018 DAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSGIGRSTAT-SSFGFKKPS 1071
                SE       GS     S + S +    ++G E      G G +T + +     K S
Sbjct: 651  ----SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVS 706

Query: 1072 GVGSSAMITSS-GATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSK 1130
              GS    TS+ G+ IT+ S T  +   ++  G ++      S +GS+         S+ 
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT---ASTEGSET-------TSAS 756

Query: 1131 TTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDS---NVSSKSAGATT--SKLREPTKIG 1185
            TT    +    + S T+     G   +  S+I S    VS+ S+  TT  ++  E T   
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1186 SGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIAS 1245
            +  S   TV+    E    + + SE+ + + +  S  T+AS  G++            AS
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE---------TTTAS 867

Query: 1246 PTFRRLFGAKAGGKSASAPNTEG--VKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGG 1303
                    A   G   +  +TEG    ++S   S +TT + +GS  +  S TGS  +   
Sbjct: 868  TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 1304 LSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY 1363
              GS +   +      T V +      +  A     T+   + +   ++S+AGS+ T   
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT-- 985

Query: 1364 QSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPK 1423
             S     T++ SI+      GS +   + T    + +  TG+  +T++ +   +  T+  
Sbjct: 986  VSTAGSETTTASIE------GSETTTVSSTGSETTTVSTTGT-ETTITSTEGSETTTVTT 1038

Query: 1424 KG-----LRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFS 1478
             G     +  T S       EG E     +TG    T + + L   + +S+S +G    S
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTVSTSGSGTTTAS 1097

Query: 1479 NLVSPT 1484
               S T
Sbjct: 1098 TAGSET 1103



 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 253/1247 (20%), Positives = 449/1247 (36%), Gaps = 139/1247 (11%)

Query: 345  STMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPS 404
            +T ++   S T T  T  S+      +    TA S   S   K     + T +      +
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253

Query: 405  SGPS-DGGKDDDAFSESGEME-----GFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSN 458
            +  S +  + + AF+E  +       GF +   +  +T S P ++  +      +  +  
Sbjct: 254  TAASTEDSETNTAFTEDSKTTTASTTGFET--TAASTTGSEPTMASTMGSETTMASTIGP 311

Query: 459  KKSLLQPKEKE--------EKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGS 510
            + + +     E         +    + V +E          T  A    S+ ++    GS
Sbjct: 312  ETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGS 371

Query: 511  KTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
            +TT A  E    +++     GS+  TV  T S  +T S    +  TT    S+  +   T
Sbjct: 372  ETTTASTEGSETTTASTE--GSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT 429

Query: 571  MEKASASSCP------APLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSH 624
            + + + +S        A     E   AS  GS T TV  ++G  T        +    S+
Sbjct: 430  VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVT-TAGSETKTAYTTGSETTTASN 488

Query: 625  PNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMR 684
                T   F   + +    T   S  +  S T  +++   T       +S    ET  + 
Sbjct: 489  TGLETTTVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS 547

Query: 685  TVKNIADLRQNLEETMSSLRG---TQISHSTLETTFDST-----------------VTTE 724
            T          LE T +S  G   T +S +  ETT DST                 V+T 
Sbjct: 548  TT--------GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 725  VNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMY-TT 783
             +  T  +     T      G          + +  A    S T+    TD    M  TT
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 784  PLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKS---LRTDDINSGY 840
               R   S  G  S+        S+  +S+E   G   +   I G     + T    +  
Sbjct: 660  GSERTITSTEG--SETTTVSATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTT 714

Query: 841  MTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTD 900
             +  G  + T S+     T  S +    G    T   +  + +S+ ++G   T  + ++ 
Sbjct: 715  TSTEGSEITTASITGSETTTASTE----GSETTTASTEGSETTSASTTGSETTTASTTSS 770

Query: 901  DLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGK 960
            +    S + S + +       T   + +  + TT  T +S   +        +     G 
Sbjct: 771  ETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAG- 829

Query: 961  WKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG---APSRQKAGTSALKTPGK-- 1015
                S  +P     AG + + + S  GS     S +G      S + + T+   T G   
Sbjct: 830  ----SETIPAST--AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883

Query: 1016 -TDDAKASEKGKAPLKGSSLQRSPSDAGK-----SSGDEGKKPPSGIGRSTATSSFGFKK 1069
             T   + SE      +GS    + ++  +     ++G E     +    +T  S+ G + 
Sbjct: 884  TTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943

Query: 1070 P--SGVGSSAMITSSGATITSGSATLGKIPKSAAIGGK-----SNAGRKT---SLDGSQN 1119
               S  GS  +  S+  + T+   T+G    +A+  G      S AG +T   S++GS+ 
Sbjct: 944  TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 1120 QDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLR 1179
                V    S+TT    +    + +ST G        S T+++ +  S  +A  TT    
Sbjct: 1004 T--TVSSTGSETTTVSTTGTETTITSTEG--------SETTTVTTAGSETTAVYTTGS-- 1051

Query: 1180 EPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQ--PG 1237
            E T   +  S   TV+ T  E    + +D E+ ++S S  S  T+AS  G++       G
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG-SGTTTASTAGSETTTVYITG 1110

Query: 1238 SKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMP--SPSTTLARQGSLESPSSGT 1295
            SK    ++        +    ++ +A +T G + ++V    S +TT++  GS  + SS  
Sbjct: 1111 SKTTTASTEGSEATTVSTTSSETTTA-STTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1296 GSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSA 1355
            GS  +     GS +   +     TT   +      ++  S     +     +   + SSA
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1229

Query: 1356 GSK--------------DTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLM 1401
            GS+               T S +   +  T SE+  + ++  G+ +  TT +     L  
Sbjct: 1230 GSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK 1289

Query: 1402 RTG-SVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEW---LRSHSTGG--LQDT 1455
             T  S++   +  M   R T    G R T SS       G ++     SH+  G  L  +
Sbjct: 1290 ATDVSIQPITNTPMSGTRTT----GTRPTASS-SVTMAPGMDFTASAASHTVPGIVLNTS 1344

Query: 1456 GNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSI 1502
            G  +  +  S+ +S+   +    +   PT+ S F   GP  M +N++
Sbjct: 1345 GLGTSTMGASSTTSAHGVRTTTGSTREPTS-STFQETGPVSMGTNTV 1390



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 218/1205 (18%), Positives = 416/1205 (34%), Gaps = 79/1205 (6%)

Query: 225  LAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKP 284
            + A   T ++ +G  T+   PT   G      + S S++   S     + + +S      
Sbjct: 30   IKASETTTASTAGSETTTPSPT---GSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTT 86

Query: 285  PNYANGNEKDSSKGPQSSSGVN--------GNVQPPSTAGQPPASAIPSPSASKPWRSKS 336
                 G+E   S     ++ V+         +     T      S+  + +++    + +
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 337  MNVKHSATSTMLTVKQSSTATSPTPSS-DRLKPPVSEGVKTAPSGQKSMLEKFKLVNART 395
            ++   S T+T  T    +TA S T S    +    SE +  + +G ++           T
Sbjct: 147  VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSET-------TTVST 199

Query: 396  ALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKN 455
            A       S+  S+      A SE+       S      +  S   VS   +   A S  
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTE 259

Query: 456  LSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAA 515
             S   +      K           T       +  +      +T+  +++ P+ +K + A
Sbjct: 260  DSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA 319

Query: 516  KKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
              E     ++G         GS+  TV  T S  +TAS    +  T   + S++     T
Sbjct: 320  SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETT----T 375

Query: 571  MEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGN---GAVQLPQQQQHSHPNT 627
                 + +  A  EG EA   S +GS T TV+ +  ++T     G+             T
Sbjct: 376  ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 628  ATV--APFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRT 685
            A+   +     + S++E T   +  S T+      S +KTA     E +          T
Sbjct: 436  ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 686  VKNIAD-----LRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPM 740
            V  I         +  E T  S  G++++  + E + ++TV+T  +  T  + T   T  
Sbjct: 496  VFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT 555

Query: 741  TWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQID 800
            T   G     +    A +       SGT+            +T       +   +     
Sbjct: 556  TSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS 615

Query: 801  MSEKASSDLDMSS-EVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRS----LNR 855
             S   S     S+   +     ++G        TD   +   T G     T +       
Sbjct: 616  ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTT 675

Query: 856  IPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNIT 915
            +  T +   +   G    TV     + +   ++G   T  +    ++ T S   S +   
Sbjct: 676  VSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735

Query: 916  VPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKA 975
                  T   +     +T+  T  S            +     G   T++S +  +  K 
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 976  GQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQ 1035
               +S   +         +++    S   + T+ + T G ++   AS  G      +S +
Sbjct: 796  STASSKMTTVFTE-----NSETTIASTTASETTTVSTAG-SETIPASTAGSETTTTTSTE 849

Query: 1036 RSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKP--SGVGSSAMITSSGATITSGSATL 1093
             S +    + G E     +    +T  ++ G +    S  GS    TS+  + T+ ++T 
Sbjct: 850  GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909

Query: 1094 GKIPKSAAIGGK-----SNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSG 1148
            G    + +  G      S  G +T+   ++  +   +  +   T+   +      S T+ 
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA----EGSETTT 965

Query: 1149 IPGRGGHRSSTSSIDSN---VSSKSAGATTSKLR--EPTKIGSGRSSPVTVNQTDKEKEK 1203
            +   G   ++ S+  S    VS+  +  TT+ +   E T + S  S   TV+ T  E   
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 1204 VAVSDSES--VSLSGSP---------KSSPTSASACGAQGLRQPGSKYPDIASPTFRRLF 1252
             +   SE+  V+ +GS          +++ TS        +   GS+    AS       
Sbjct: 1026 TSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSE-TTTASTADLETT 1084

Query: 1253 GAKAGGKSASAPNTEGVKSSSVM--PSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSP 1310
                 G   +  +T G ++++V    S +TT + +GS  +  S T S  +    +GS   
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144

Query: 1311 LFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLH 1370
                    TT V ++     +S A+    T+     +   ++S+AGS+ T +  + +   
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETT 1204

Query: 1371 TSSES 1375
            T+S S
Sbjct: 1205 TASTS 1209



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 171/889 (19%), Positives = 324/889 (36%), Gaps = 70/889 (7%)

Query: 999  APSRQKAGTSALKTPGKTDDA--KASEKGKAPLKGSSLQRSPSDAGKS------SGDEGK 1050
            AP+     T+A  T  +T     KASE   A   GS    +PS  G        SG E  
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT-TPSPTGSQTTIVSISGSEIT 66

Query: 1051 KPPSGIGRSTATSSFGF--KKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNA 1108
               +    +T  SS G      S  GS   ++++G+  T+ S T  +    +A+G ++  
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 1109 GRKTSLDGSQ-----NQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSID 1163
               TS + +      ++   V  V S+TT  Y +    + +ST+G        + + +I 
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 1164 SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES--VSLSGSPKSS 1221
             + +       ++   E T + +  S   T +    E    +   SE+  VS +GS  + 
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 1222 PTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS--SVMPSPS 1279
             T+ S   A       +   + A     +   A   G   +A +T G + +  S M S +
Sbjct: 247  STAGSETTAASTEDSET---NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 1280 TTLARQG----SLESPSSGTGSMGSAGGLSGSSSPLFNKPSDL-TTDVISLSHSLASSPA 1334
            T  +  G     + + SS   ++ +AG  +  +S + ++ + + TT   + + S+  S  
Sbjct: 304  TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTH 1394
            S  S T+G     A+   S   +  T   ++ T   T SE+  + ++     S  TT   
Sbjct: 364  STDS-TTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITD----SETTTTCT 418

Query: 1395 EVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQD 1454
            E   +   + +V  T + S +    T+       T ++     E          T     
Sbjct: 419  EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478

Query: 1455 TGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDD 1514
            TG+++   S + + ++           + T  S+      +     ++  + S       
Sbjct: 479  TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVST 538

Query: 1515 SQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKL 1574
            +   GS T+       +S +G    +     GS ++ VS+T      AE    S +    
Sbjct: 539  T---GSETT------TVSTTG-LETTTTSTEGSEMTTVSTTG-----AETTTDSTEGSGT 583

Query: 1575 RRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELI----EL 1630
                 A  E     T+         A  E +  + TG   S T TA    SE      E 
Sbjct: 584  TAASTAGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEG 640

Query: 1631 RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 1690
             ET  +    +     +  G+        + +       + +VS+  S T+ S+ GSG  
Sbjct: 641  SETTTVSTTDSETTMVSTTGS-------ERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 1750
              S    +   V++ GSE  ++  +  G + +T   +        T+ S   +       
Sbjct: 694  TVSITGSETTKVSTTGSETTTTSTE--GSEITTASITGSETTTASTEGSETTTAST--EG 749

Query: 1751 GDCGSASMKPSQSASAICECTEAEAEIIL----QLKSELREKELKLTDIRLEALSSAHHL 1806
             +  SAS   S++ +A    +E     I+     + S +  +  K++    +  +     
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 1807 DQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSS 1855
             +   A         +  A ++ + A T  +   T   +E S +T++S+
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score =  104 bits (259), Expect = 1e-21
 Identities = 245/1206 (20%), Positives = 436/1206 (36%), Gaps = 142/1206 (11%)

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEG 373
            T   P A +  + +++    + ++ +K S T+T  T    +T  SPT S   +   +S  
Sbjct: 5    TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI-VSISGS 63

Query: 374  VKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
              T  S   S         + T         +  S  G +    S +G      S + S 
Sbjct: 64   EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 434  GSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
             +TNS+   S       AGS+  +                  + V +E       D  T 
Sbjct: 124  TTTNSTTS-SETTVTSTAGSETTT-----------------VSTVGSETTTAYTADSETT 165

Query: 494  MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTAS 548
             A    S++ ++   GS       E++ PS++G     +   GS+  TV  T S  +TAS
Sbjct: 166  AASTTGSEMTTVFTAGS-------ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218

Query: 549  KESEK--FRTTKGSPSQSLS---KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVA- 602
                +    +T GS +  +S      T+  A + +  A  E  E   A    S T T + 
Sbjct: 219  TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278

Query: 603  ---QSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYR-AHSENEGTALPSADSCTSPTKM 658
               +++  ST      +           +T+ P   + + + +E T + +A S T     
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 659  DLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFD 718
              S + T        +G +  T  +   +   D     E T +S  G++ + ++ E +  
Sbjct: 339  VGSETTTV-----STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 719  STVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSR 778
            +TV+T  +  T  ++T   T  T   G                       S       + 
Sbjct: 394  TTVSTTGSETTTVSITDSETTTTCTEG-----------------------SEMTAVSTTV 430

Query: 779  FMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINS 838
            F  TT     +   + + S  + +  ++   + ++    G         G    T   N+
Sbjct: 431  FETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTAS-NT 489

Query: 839  GYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIS 898
            G  T     + + +     + + +  +   G    TV  +  ++++  ++G   T   +S
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT--TVS 547

Query: 899  TDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAG 958
            T  L TT++ +  S +T  S    +  TDS + S T                  +   AG
Sbjct: 548  TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT-----------------TAASTAG 590

Query: 959  GKWKTVSSGLPED-PEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD 1017
             +  TVS+   E+         + S S TGS     S      +      S   T   TD
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 1018 DAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSGIGRSTAT-SSFGFKKPS 1071
                SE       GS     S + S +    ++G E      G G +T + +     K S
Sbjct: 651  ----SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVS 706

Query: 1072 GVGSSAMITSS-GATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSK 1130
              GS    TS+ G+ IT+ S T  +   ++  G ++      S +GS+         S+ 
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT---ASTEGSET-------TSAS 756

Query: 1131 TTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDS---NVSSKSAGATT--SKLREPTKIG 1185
            TT    +    + S T+     G   +  S+I S    VS+ S+  TT  ++  E T   
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1186 SGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIAS 1245
            +  S   TV+    E    + + SE+ + + +  S  T+AS  G++            AS
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE---------TTTAS 867

Query: 1246 PTFRRLFGAKAGGKSASAPNTEG--VKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGG 1303
                    A   G   +  +TEG    ++S   S +TT + +GS  +  S TGS  +   
Sbjct: 868  TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 1304 LSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY 1363
              GS +   +      T V +      +  A     T+   + +   ++S+AGS+ T   
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT-- 985

Query: 1364 QSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPK 1423
             S     T++ SI+      GS +   + T    + +  TG+  +T++ +   +  T+  
Sbjct: 986  VSTAGSETTTASIE------GSETTTVSSTGSETTTVSTTGT-ETTITSTEGSETTTVTT 1038

Query: 1424 KG-----LRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFS 1478
             G     +  T S       EG E     +TG    T + + L   + +S+S +G    S
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTVSTSGSGTTTAS 1097

Query: 1479 NLVSPT 1484
               S T
Sbjct: 1098 TAGSET 1103



 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 253/1247 (20%), Positives = 449/1247 (36%), Gaps = 139/1247 (11%)

Query: 345  STMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPS 404
            +T ++   S T T  T  S+      +    TA S   S   K     + T +      +
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253

Query: 405  SGPS-DGGKDDDAFSESGEME-----GFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSN 458
            +  S +  + + AF+E  +       GF +   +  +T S P ++  +      +  +  
Sbjct: 254  TAASTEDSETNTAFTEDSKTTTASTTGFET--TAASTTGSEPTMASTMGSETTMASTIGP 311

Query: 459  KKSLLQPKEKE--------EKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGS 510
            + + +     E         +    + V +E          T  A    S+ ++    GS
Sbjct: 312  ETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGS 371

Query: 511  KTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
            +TT A  E    +++     GS+  TV  T S  +T S    +  TT    S+  +   T
Sbjct: 372  ETTTASTEGSETTTASTE--GSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT 429

Query: 571  MEKASASSCP------APLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSH 624
            + + + +S        A     E   AS  GS T TV  ++G  T        +    S+
Sbjct: 430  VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVT-TAGSETKTAYTTGSETTTASN 488

Query: 625  PNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMR 684
                T   F   + +    T   S  +  S T  +++   T       +S    ET  + 
Sbjct: 489  TGLETTTVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS 547

Query: 685  TVKNIADLRQNLEETMSSLRG---TQISHSTLETTFDST-----------------VTTE 724
            T          LE T +S  G   T +S +  ETT DST                 V+T 
Sbjct: 548  TT--------GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 725  VNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMY-TT 783
             +  T  +     T      G          + +  A    S T+    TD    M  TT
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 784  PLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKS---LRTDDINSGY 840
               R   S  G  S+        S+  +S+E   G   +   I G     + T    +  
Sbjct: 660  GSERTITSTEG--SETTTVSATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTT 714

Query: 841  MTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTD 900
             +  G  + T S+     T  S +    G    T   +  + +S+ ++G   T  + ++ 
Sbjct: 715  TSTEGSEITTASITGSETTTASTE----GSETTTASTEGSETTSASTTGSETTTASTTSS 770

Query: 901  DLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGK 960
            +    S + S + +       T   + +  + TT  T +S   +        +     G 
Sbjct: 771  ETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAG- 829

Query: 961  WKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG---APSRQKAGTSALKTPGK-- 1015
                S  +P     AG + + + S  GS     S +G      S + + T+   T G   
Sbjct: 830  ----SETIPAST--AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883

Query: 1016 -TDDAKASEKGKAPLKGSSLQRSPSDAGK-----SSGDEGKKPPSGIGRSTATSSFGFKK 1069
             T   + SE      +GS    + ++  +     ++G E     +    +T  S+ G + 
Sbjct: 884  TTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943

Query: 1070 P--SGVGSSAMITSSGATITSGSATLGKIPKSAAIGGK-----SNAGRKT---SLDGSQN 1119
               S  GS  +  S+  + T+   T+G    +A+  G      S AG +T   S++GS+ 
Sbjct: 944  TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 1120 QDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLR 1179
                V    S+TT    +    + +ST G        S T+++ +  S  +A  TT    
Sbjct: 1004 T--TVSSTGSETTTVSTTGTETTITSTEG--------SETTTVTTAGSETTAVYTTGS-- 1051

Query: 1180 EPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQ--PG 1237
            E T   +  S   TV+ T  E    + +D E+ ++S S  S  T+AS  G++       G
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG-SGTTTASTAGSETTTVYITG 1110

Query: 1238 SKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMP--SPSTTLARQGSLESPSSGT 1295
            SK    ++        +    ++ +A +T G + ++V    S +TT++  GS  + SS  
Sbjct: 1111 SKTTTASTEGSEATTVSTTSSETTTA-STTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1296 GSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSA 1355
            GS  +     GS +   +     TT   +      ++  S     +     +   + SSA
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1229

Query: 1356 GSK--------------DTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLM 1401
            GS+               T S +   +  T SE+  + ++  G+ +  TT +     L  
Sbjct: 1230 GSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK 1289

Query: 1402 RTG-SVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEW---LRSHSTGG--LQDT 1455
             T  S++   +  M   R T    G R T SS       G ++     SH+  G  L  +
Sbjct: 1290 ATDVSIQPITNTPMSGTRTT----GTRPTASS-SVTMAPGMDFTASAASHTVPGIVLNTS 1344

Query: 1456 GNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSI 1502
            G  +  +  S+ +S+   +    +   PT+ S F   GP  M +N++
Sbjct: 1345 GLGTSTMGASSTTSAHGVRTTTGSTREPTS-STFQETGPVSMGTNTV 1390



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 218/1205 (18%), Positives = 416/1205 (34%), Gaps = 79/1205 (6%)

Query: 225  LAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKP 284
            + A   T ++ +G  T+   PT   G      + S S++   S     + + +S      
Sbjct: 30   IKASETTTASTAGSETTTPSPT---GSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTT 86

Query: 285  PNYANGNEKDSSKGPQSSSGVN--------GNVQPPSTAGQPPASAIPSPSASKPWRSKS 336
                 G+E   S     ++ V+         +     T      S+  + +++    + +
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 337  MNVKHSATSTMLTVKQSSTATSPTPSS-DRLKPPVSEGVKTAPSGQKSMLEKFKLVNART 395
            ++   S T+T  T    +TA S T S    +    SE +  + +G ++           T
Sbjct: 147  VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSET-------TTVST 199

Query: 396  ALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKN 455
            A       S+  S+      A SE+       S      +  S   VS   +   A S  
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTE 259

Query: 456  LSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAA 515
             S   +      K           T       +  +      +T+  +++ P+ +K + A
Sbjct: 260  DSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA 319

Query: 516  KKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
              E     ++G         GS+  TV  T S  +TAS    +  T   + S++     T
Sbjct: 320  SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETT----T 375

Query: 571  MEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGN---GAVQLPQQQQHSHPNT 627
                 + +  A  EG EA   S +GS T TV+ +  ++T     G+             T
Sbjct: 376  ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 628  ATV--APFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRT 685
            A+   +     + S++E T   +  S T+      S +KTA     E +          T
Sbjct: 436  ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 686  VKNIAD-----LRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPM 740
            V  I         +  E T  S  G++++  + E + ++TV+T  +  T  + T   T  
Sbjct: 496  VFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT 555

Query: 741  TWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQID 800
            T   G     +    A +       SGT+            +T       +   +     
Sbjct: 556  TSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS 615

Query: 801  MSEKASSDLDMSS-EVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRS----LNR 855
             S   S     S+   +     ++G        TD   +   T G     T +       
Sbjct: 616  ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTT 675

Query: 856  IPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNIT 915
            +  T +   +   G    TV     + +   ++G   T  +    ++ T S   S +   
Sbjct: 676  VSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735

Query: 916  VPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKA 975
                  T   +     +T+  T  S            +     G   T++S +  +  K 
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 976  GQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQ 1035
               +S   +         +++    S   + T+ + T G ++   AS  G      +S +
Sbjct: 796  STASSKMTTVFTE-----NSETTIASTTASETTTVSTAG-SETIPASTAGSETTTTTSTE 849

Query: 1036 RSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKP--SGVGSSAMITSSGATITSGSATL 1093
             S +    + G E     +    +T  ++ G +    S  GS    TS+  + T+ ++T 
Sbjct: 850  GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909

Query: 1094 GKIPKSAAIGGK-----SNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSG 1148
            G    + +  G      S  G +T+   ++  +   +  +   T+   +      S T+ 
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA----EGSETTT 965

Query: 1149 IPGRGGHRSSTSSIDSN---VSSKSAGATTSKLR--EPTKIGSGRSSPVTVNQTDKEKEK 1203
            +   G   ++ S+  S    VS+  +  TT+ +   E T + S  S   TV+ T  E   
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 1204 VAVSDSES--VSLSGSP---------KSSPTSASACGAQGLRQPGSKYPDIASPTFRRLF 1252
             +   SE+  V+ +GS          +++ TS        +   GS+    AS       
Sbjct: 1026 TSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSE-TTTASTADLETT 1084

Query: 1253 GAKAGGKSASAPNTEGVKSSSVM--PSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSP 1310
                 G   +  +T G ++++V    S +TT + +GS  +  S T S  +    +GS   
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144

Query: 1311 LFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLH 1370
                    TT V ++     +S A+    T+     +   ++S+AGS+ T +  + +   
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETT 1204

Query: 1371 TSSES 1375
            T+S S
Sbjct: 1205 TASTS 1209



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 171/889 (19%), Positives = 324/889 (36%), Gaps = 70/889 (7%)

Query: 999  APSRQKAGTSALKTPGKTDDA--KASEKGKAPLKGSSLQRSPSDAGKS------SGDEGK 1050
            AP+     T+A  T  +T     KASE   A   GS    +PS  G        SG E  
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT-TPSPTGSQTTIVSISGSEIT 66

Query: 1051 KPPSGIGRSTATSSFGF--KKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNA 1108
               +    +T  SS G      S  GS   ++++G+  T+ S T  +    +A+G ++  
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 1109 GRKTSLDGSQ-----NQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSID 1163
               TS + +      ++   V  V S+TT  Y +    + +ST+G        + + +I 
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 1164 SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES--VSLSGSPKSS 1221
             + +       ++   E T + +  S   T +    E    +   SE+  VS +GS  + 
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 1222 PTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS--SVMPSPS 1279
             T+ S   A       +   + A     +   A   G   +A +T G + +  S M S +
Sbjct: 247  STAGSETTAASTEDSET---NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 1280 TTLARQG----SLESPSSGTGSMGSAGGLSGSSSPLFNKPSDL-TTDVISLSHSLASSPA 1334
            T  +  G     + + SS   ++ +AG  +  +S + ++ + + TT   + + S+  S  
Sbjct: 304  TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTH 1394
            S  S T+G     A+   S   +  T   ++ T   T SE+  + ++     S  TT   
Sbjct: 364  STDS-TTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITD----SETTTTCT 418

Query: 1395 EVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQD 1454
            E   +   + +V  T + S +    T+       T ++     E          T     
Sbjct: 419  EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478

Query: 1455 TGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDD 1514
            TG+++   S + + ++           + T  S+      +     ++  + S       
Sbjct: 479  TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVST 538

Query: 1515 SQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKL 1574
            +   GS T+       +S +G    +     GS ++ VS+T      AE    S +    
Sbjct: 539  T---GSETT------TVSTTG-LETTTTSTEGSEMTTVSTTG-----AETTTDSTEGSGT 583

Query: 1575 RRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELI----EL 1630
                 A  E     T+         A  E +  + TG   S T TA    SE      E 
Sbjct: 584  TAASTAGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEG 640

Query: 1631 RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 1690
             ET  +    +     +  G+        + +       + +VS+  S T+ S+ GSG  
Sbjct: 641  SETTTVSTTDSETTMVSTTGS-------ERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 1750
              S    +   V++ GSE  ++  +  G + +T   +        T+ S   +       
Sbjct: 694  TVSITGSETTKVSTTGSETTTTSTE--GSEITTASITGSETTTASTEGSETTTAST--EG 749

Query: 1751 GDCGSASMKPSQSASAICECTEAEAEIIL----QLKSELREKELKLTDIRLEALSSAHHL 1806
             +  SAS   S++ +A    +E     I+     + S +  +  K++    +  +     
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 1807 DQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSS 1855
             +   A         +  A ++ + A T  +   T   +E S +T++S+
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score =  104 bits (259), Expect = 1e-21
 Identities = 245/1206 (20%), Positives = 436/1206 (36%), Gaps = 142/1206 (11%)

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEG 373
            T   P A +  + +++    + ++ +K S T+T  T    +T  SPT S   +   +S  
Sbjct: 5    TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI-VSISGS 63

Query: 374  VKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
              T  S   S         + T         +  S  G +    S +G      S + S 
Sbjct: 64   EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 434  GSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
             +TNS+   S       AGS+  +                  + V +E       D  T 
Sbjct: 124  TTTNSTTS-SETTVTSTAGSETTT-----------------VSTVGSETTTAYTADSETT 165

Query: 494  MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTAS 548
             A    S++ ++   GS       E++ PS++G     +   GS+  TV  T S  +TAS
Sbjct: 166  AASTTGSEMTTVFTAGS-------ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218

Query: 549  KESEK--FRTTKGSPSQSLS---KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVA- 602
                +    +T GS +  +S      T+  A + +  A  E  E   A    S T T + 
Sbjct: 219  TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278

Query: 603  ---QSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYR-AHSENEGTALPSADSCTSPTKM 658
               +++  ST      +           +T+ P   + + + +E T + +A S T     
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 659  DLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFD 718
              S + T        +G +  T  +   +   D     E T +S  G++ + ++ E +  
Sbjct: 339  VGSETTTV-----STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 719  STVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSR 778
            +TV+T  +  T  ++T   T  T   G                       S       + 
Sbjct: 394  TTVSTTGSETTTVSITDSETTTTCTEG-----------------------SEMTAVSTTV 430

Query: 779  FMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINS 838
            F  TT     +   + + S  + +  ++   + ++    G         G    T   N+
Sbjct: 431  FETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTAS-NT 489

Query: 839  GYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIS 898
            G  T     + + +     + + +  +   G    TV  +  ++++  ++G   T   +S
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT--TVS 547

Query: 899  TDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAG 958
            T  L TT++ +  S +T  S    +  TDS + S T                  +   AG
Sbjct: 548  TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT-----------------TAASTAG 590

Query: 959  GKWKTVSSGLPED-PEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD 1017
             +  TVS+   E+         + S S TGS     S      +      S   T   TD
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 1018 DAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSGIGRSTAT-SSFGFKKPS 1071
                SE       GS     S + S +    ++G E      G G +T + +     K S
Sbjct: 651  ----SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVS 706

Query: 1072 GVGSSAMITSS-GATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSK 1130
              GS    TS+ G+ IT+ S T  +   ++  G ++      S +GS+         S+ 
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT---ASTEGSET-------TSAS 756

Query: 1131 TTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDS---NVSSKSAGATT--SKLREPTKIG 1185
            TT    +    + S T+     G   +  S+I S    VS+ S+  TT  ++  E T   
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1186 SGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIAS 1245
            +  S   TV+    E    + + SE+ + + +  S  T+AS  G++            AS
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE---------TTTAS 867

Query: 1246 PTFRRLFGAKAGGKSASAPNTEG--VKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGG 1303
                    A   G   +  +TEG    ++S   S +TT + +GS  +  S TGS  +   
Sbjct: 868  TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 1304 LSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY 1363
              GS +   +      T V +      +  A     T+   + +   ++S+AGS+ T   
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT-- 985

Query: 1364 QSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPK 1423
             S     T++ SI+      GS +   + T    + +  TG+  +T++ +   +  T+  
Sbjct: 986  VSTAGSETTTASIE------GSETTTVSSTGSETTTVSTTGT-ETTITSTEGSETTTVTT 1038

Query: 1424 KG-----LRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFS 1478
             G     +  T S       EG E     +TG    T + + L   + +S+S +G    S
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTVSTSGSGTTTAS 1097

Query: 1479 NLVSPT 1484
               S T
Sbjct: 1098 TAGSET 1103



 Score = 71.6 bits (174), Expect = 8e-12
 Identities = 195/988 (19%), Positives = 343/988 (34%), Gaps = 87/988 (8%)

Query: 256  AAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTA 315
            A+ S S+   AS     + +  +        Y  G+E  ++      +     +   +T 
Sbjct: 446  ASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 316  GQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTP-SSDRLKPPVSEGV 374
                 S   + SA+      +++ + S  +T+ T    +T  S T   +       SE  
Sbjct: 506  ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT 564

Query: 375  KTAPSGQKSMLEKFK---LVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLN 431
              + +G ++  +  +      A TA       S+  S+      A SE+       S   
Sbjct: 565  TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624

Query: 432  SGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQP--KEKEEKNRDKNKVCTEKPVKEEKD 489
            +  +T+S    +              ++ +++     E+   + + ++  T      E  
Sbjct: 625  TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 490  QVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASK 549
              TE +   T  I      GS+TT  K  +    ++     GS++ T   T S  +TAS 
Sbjct: 685  VSTEGSGTTTVSIT-----GSETT--KVSTTGSETTTTSTEGSEITTASITGSETTTAST 737

Query: 550  ESEKFRT--TKGSPSQSLS----KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQ 603
            E  +  T  T+GS + S S    +  T    S+ +  A + G E   AS  GS T  V+ 
Sbjct: 738  EGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVST 797

Query: 604  SSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSEN--EGTALPSADSCTSPTKMDLS 661
            +S + T    V     +      TA+    +  A SE     TA     + TS    + +
Sbjct: 798  ASSKMT---TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 854

Query: 662  YSKTAKQCLEEISGEDPETRRMRTV--KNIADLRQNLEETMSSLRGTQISHSTLETTFDS 719
             + T        S E  ET    T+  +      +  E T +S  G++ + ++ E +  +
Sbjct: 855  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 914

Query: 720  TVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRF 779
            TV+T  +  T  +     T      G     +    + ++      S T     T  +  
Sbjct: 915  TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSET-----TTVTTM 969

Query: 780  MYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSG 839
               T     A S    +S    SE  ++ ++ S    V    S+   +  +     I S 
Sbjct: 970  GSETTTASTAGSETTTVSTAG-SETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS- 1027

Query: 840  YMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIST 899
              T+G           +    +    +     + T  +    ++++VS+  S+T    ST
Sbjct: 1028 --TEGS------ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETT-TAST 1078

Query: 900  DDLNTTSSVSSYSNITVPSRKNTQLRT---DSEKRSTTDETWDSPEELKKPEEDFDSHGD 956
             DL TT+  +S S  T  S   ++  T      K +T          +     +  +   
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1138

Query: 957  AGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG---APSRQKAGTSALKTP 1013
             G +  TV + + E         + +VS  GS     SA G      S + + T+   T 
Sbjct: 1139 TGSEMTTVFTTVSE---------TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTA 1189

Query: 1014 GK---TDDAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSG---------I 1056
            G    T     SE   A   GS     S   S ++   ++G E   P S          I
Sbjct: 1190 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1249

Query: 1057 GRSTATSSFGFKKPSGVG------SSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGR 1110
            G  T  +S    +P+         ++  IT+SGAT  S + +      + A         
Sbjct: 1250 GSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPIT 1309

Query: 1111 KTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPG----RGGHRSSTSSIDSNV 1166
             T + G++     +   SS T          + S T  +PG      G  +ST    S  
Sbjct: 1310 NTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHT--VPGIVLNTSGLGTSTMGASSTT 1367

Query: 1167 SSKSAGATTSKLREPTKIGSGRSSPVTV 1194
            S+     TT   REPT      + PV++
Sbjct: 1368 SAHGVRTTTGSTREPTSSTFQETGPVSM 1395



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 171/889 (19%), Positives = 324/889 (36%), Gaps = 70/889 (7%)

Query: 999  APSRQKAGTSALKTPGKTDDA--KASEKGKAPLKGSSLQRSPSDAGKS------SGDEGK 1050
            AP+     T+A  T  +T     KASE   A   GS    +PS  G        SG E  
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT-TPSPTGSQTTIVSISGSEIT 66

Query: 1051 KPPSGIGRSTATSSFGF--KKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNA 1108
               +    +T  SS G      S  GS   ++++G+  T+ S T  +    +A+G ++  
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 1109 GRKTSLDGSQ-----NQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSID 1163
               TS + +      ++   V  V S+TT  Y +    + +ST+G        + + +I 
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 1164 SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES--VSLSGSPKSS 1221
             + +       ++   E T + +  S   T +    E    +   SE+  VS +GS  + 
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 1222 PTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS--SVMPSPS 1279
             T+ S   A       +   + A     +   A   G   +A +T G + +  S M S +
Sbjct: 247  STAGSETTAASTEDSET---NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 1280 TTLARQG----SLESPSSGTGSMGSAGGLSGSSSPLFNKPSDL-TTDVISLSHSLASSPA 1334
            T  +  G     + + SS   ++ +AG  +  +S + ++ + + TT   + + S+  S  
Sbjct: 304  TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTH 1394
            S  S T+G     A+   S   +  T   ++ T   T SE+  + ++     S  TT   
Sbjct: 364  STDS-TTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITD----SETTTTCT 418

Query: 1395 EVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQD 1454
            E   +   + +V  T + S +    T+       T ++     E          T     
Sbjct: 419  EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478

Query: 1455 TGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDD 1514
            TG+++   S + + ++           + T  S+      +     ++  + S       
Sbjct: 479  TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVST 538

Query: 1515 SQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKL 1574
            +   GS T+       +S +G    +     GS ++ VS+T      AE    S +    
Sbjct: 539  T---GSETT------TVSTTG-LETTTTSTEGSEMTTVSTTG-----AETTTDSTEGSGT 583

Query: 1575 RRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELI----EL 1630
                 A  E     T+         A  E +  + TG   S T TA    SE      E 
Sbjct: 584  TAASTAGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEG 640

Query: 1631 RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 1690
             ET  +    +     +  G+        + +       + +VS+  S T+ S+ GSG  
Sbjct: 641  SETTTVSTTDSETTMVSTTGS-------ERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 1750
              S    +   V++ GSE  ++  +  G + +T   +        T+ S   +       
Sbjct: 694  TVSITGSETTKVSTTGSETTTTSTE--GSEITTASITGSETTTASTEGSETTTAST--EG 749

Query: 1751 GDCGSASMKPSQSASAICECTEAEAEIIL----QLKSELREKELKLTDIRLEALSSAHHL 1806
             +  SAS   S++ +A    +E     I+     + S +  +  K++    +  +     
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 1807 DQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSS 1855
             +   A         +  A ++ + A T  +   T   +E S +T++S+
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score =  104 bits (259), Expect = 1e-21
 Identities = 245/1206 (20%), Positives = 436/1206 (36%), Gaps = 142/1206 (11%)

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEG 373
            T   P A +  + +++    + ++ +K S T+T  T    +T  SPT S   +   +S  
Sbjct: 5    TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI-VSISGS 63

Query: 374  VKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
              T  S   S         + T         +  S  G +    S +G      S + S 
Sbjct: 64   EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 434  GSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
             +TNS+   S       AGS+  +                  + V +E       D  T 
Sbjct: 124  TTTNSTTS-SETTVTSTAGSETTT-----------------VSTVGSETTTAYTADSETT 165

Query: 494  MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTAS 548
             A    S++ ++   GS       E++ PS++G     +   GS+  TV  T S  +TAS
Sbjct: 166  AASTTGSEMTTVFTAGS-------ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218

Query: 549  KESEK--FRTTKGSPSQSLS---KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVA- 602
                +    +T GS +  +S      T+  A + +  A  E  E   A    S T T + 
Sbjct: 219  TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278

Query: 603  ---QSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYR-AHSENEGTALPSADSCTSPTKM 658
               +++  ST      +           +T+ P   + + + +E T + +A S T     
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 659  DLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFD 718
              S + T        +G +  T  +   +   D     E T +S  G++ + ++ E +  
Sbjct: 339  VGSETTTV-----STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 719  STVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSR 778
            +TV+T  +  T  ++T   T  T   G                       S       + 
Sbjct: 394  TTVSTTGSETTTVSITDSETTTTCTEG-----------------------SEMTAVSTTV 430

Query: 779  FMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINS 838
            F  TT     +   + + S  + +  ++   + ++    G         G    T   N+
Sbjct: 431  FETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTAS-NT 489

Query: 839  GYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIS 898
            G  T     + + +     + + +  +   G    TV  +  ++++  ++G   T   +S
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT--TVS 547

Query: 899  TDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAG 958
            T  L TT++ +  S +T  S    +  TDS + S T                  +   AG
Sbjct: 548  TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT-----------------TAASTAG 590

Query: 959  GKWKTVSSGLPED-PEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD 1017
             +  TVS+   E+         + S S TGS     S      +      S   T   TD
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 1018 DAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSGIGRSTAT-SSFGFKKPS 1071
                SE       GS     S + S +    ++G E      G G +T + +     K S
Sbjct: 651  ----SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVS 706

Query: 1072 GVGSSAMITSS-GATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSK 1130
              GS    TS+ G+ IT+ S T  +   ++  G ++      S +GS+         S+ 
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT---ASTEGSET-------TSAS 756

Query: 1131 TTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDS---NVSSKSAGATT--SKLREPTKIG 1185
            TT    +    + S T+     G   +  S+I S    VS+ S+  TT  ++  E T   
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1186 SGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIAS 1245
            +  S   TV+    E    + + SE+ + + +  S  T+AS  G++            AS
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE---------TTTAS 867

Query: 1246 PTFRRLFGAKAGGKSASAPNTEG--VKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGG 1303
                    A   G   +  +TEG    ++S   S +TT + +GS  +  S TGS  +   
Sbjct: 868  TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 1304 LSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY 1363
              GS +   +      T V +      +  A     T+   + +   ++S+AGS+ T   
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT-- 985

Query: 1364 QSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPK 1423
             S     T++ SI+      GS +   + T    + +  TG+  +T++ +   +  T+  
Sbjct: 986  VSTAGSETTTASIE------GSETTTVSSTGSETTTVSTTGT-ETTITSTEGSETTTVTT 1038

Query: 1424 KG-----LRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFS 1478
             G     +  T S       EG E     +TG    T + + L   + +S+S +G    S
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTVSTSGSGTTTAS 1097

Query: 1479 NLVSPT 1484
               S T
Sbjct: 1098 TAGSET 1103



 Score = 71.6 bits (174), Expect = 8e-12
 Identities = 195/988 (19%), Positives = 343/988 (34%), Gaps = 87/988 (8%)

Query: 256  AAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTA 315
            A+ S S+   AS     + +  +        Y  G+E  ++      +     +   +T 
Sbjct: 446  ASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT 505

Query: 316  GQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTP-SSDRLKPPVSEGV 374
                 S   + SA+      +++ + S  +T+ T    +T  S T   +       SE  
Sbjct: 506  ASTEGSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT 564

Query: 375  KTAPSGQKSMLEKFK---LVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLN 431
              + +G ++  +  +      A TA       S+  S+      A SE+       S   
Sbjct: 565  TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624

Query: 432  SGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQP--KEKEEKNRDKNKVCTEKPVKEEKD 489
            +  +T+S    +              ++ +++     E+   + + ++  T      E  
Sbjct: 625  TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 490  QVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASK 549
              TE +   T  I      GS+TT  K  +    ++     GS++ T   T S  +TAS 
Sbjct: 685  VSTEGSGTTTVSIT-----GSETT--KVSTTGSETTTTSTEGSEITTASITGSETTTAST 737

Query: 550  ESEKFRT--TKGSPSQSLS----KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQ 603
            E  +  T  T+GS + S S    +  T    S+ +  A + G E   AS  GS T  V+ 
Sbjct: 738  EGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVST 797

Query: 604  SSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSEN--EGTALPSADSCTSPTKMDLS 661
            +S + T    V     +      TA+    +  A SE     TA     + TS    + +
Sbjct: 798  ASSKMT---TVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 854

Query: 662  YSKTAKQCLEEISGEDPETRRMRTV--KNIADLRQNLEETMSSLRGTQISHSTLETTFDS 719
             + T        S E  ET    T+  +      +  E T +S  G++ + ++ E +  +
Sbjct: 855  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 914

Query: 720  TVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRF 779
            TV+T  +  T  +     T      G     +    + ++      S T     T  +  
Sbjct: 915  TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSET-----TTVTTM 969

Query: 780  MYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSG 839
               T     A S    +S    SE  ++ ++ S    V    S+   +  +     I S 
Sbjct: 970  GSETTTASTAGSETTTVSTAG-SETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS- 1027

Query: 840  YMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIST 899
              T+G           +    +    +     + T  +    ++++VS+  S+T    ST
Sbjct: 1028 --TEGS------ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETT-TAST 1078

Query: 900  DDLNTTSSVSSYSNITVPSRKNTQLRT---DSEKRSTTDETWDSPEELKKPEEDFDSHGD 956
             DL TT+  +S S  T  S   ++  T      K +T          +     +  +   
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1138

Query: 957  AGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG---APSRQKAGTSALKTP 1013
             G +  TV + + E         + +VS  GS     SA G      S + + T+   T 
Sbjct: 1139 TGSEMTTVFTTVSE---------TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTA 1189

Query: 1014 GK---TDDAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSG---------I 1056
            G    T     SE   A   GS     S   S ++   ++G E   P S          I
Sbjct: 1190 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1249

Query: 1057 GRSTATSSFGFKKPSGVG------SSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGR 1110
            G  T  +S    +P+         ++  IT+SGAT  S + +      + A         
Sbjct: 1250 GSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPIT 1309

Query: 1111 KTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPG----RGGHRSSTSSIDSNV 1166
             T + G++     +   SS T          + S T  +PG      G  +ST    S  
Sbjct: 1310 NTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHT--VPGIVLNTSGLGTSTMGASSTT 1367

Query: 1167 SSKSAGATTSKLREPTKIGSGRSSPVTV 1194
            S+     TT   REPT      + PV++
Sbjct: 1368 SAHGVRTTTGSTREPTSSTFQETGPVSM 1395



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 171/889 (19%), Positives = 324/889 (36%), Gaps = 70/889 (7%)

Query: 999  APSRQKAGTSALKTPGKTDDA--KASEKGKAPLKGSSLQRSPSDAGKS------SGDEGK 1050
            AP+     T+A  T  +T     KASE   A   GS    +PS  G        SG E  
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT-TPSPTGSQTTIVSISGSEIT 66

Query: 1051 KPPSGIGRSTATSSFGF--KKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNA 1108
               +    +T  SS G      S  GS   ++++G+  T+ S T  +    +A+G ++  
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 1109 GRKTSLDGSQ-----NQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSID 1163
               TS + +      ++   V  V S+TT  Y +    + +ST+G        + + +I 
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 1164 SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES--VSLSGSPKSS 1221
             + +       ++   E T + +  S   T +    E    +   SE+  VS +GS  + 
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 1222 PTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS--SVMPSPS 1279
             T+ S   A       +   + A     +   A   G   +A +T G + +  S M S +
Sbjct: 247  STAGSETTAASTEDSET---NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 1280 TTLARQG----SLESPSSGTGSMGSAGGLSGSSSPLFNKPSDL-TTDVISLSHSLASSPA 1334
            T  +  G     + + SS   ++ +AG  +  +S + ++ + + TT   + + S+  S  
Sbjct: 304  TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTH 1394
            S  S T+G     A+   S   +  T   ++ T   T SE+  + ++     S  TT   
Sbjct: 364  STDS-TTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITD----SETTTTCT 418

Query: 1395 EVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQD 1454
            E   +   + +V  T + S +    T+       T ++     E          T     
Sbjct: 419  EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478

Query: 1455 TGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDD 1514
            TG+++   S + + ++           + T  S+      +     ++  + S       
Sbjct: 479  TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVST 538

Query: 1515 SQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKL 1574
            +   GS T+       +S +G    +     GS ++ VS+T      AE    S +    
Sbjct: 539  T---GSETT------TVSTTG-LETTTTSTEGSEMTTVSTTG-----AETTTDSTEGSGT 583

Query: 1575 RRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELI----EL 1630
                 A  E     T+         A  E +  + TG   S T TA    SE      E 
Sbjct: 584  TAASTAGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEG 640

Query: 1631 RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 1690
             ET  +    +     +  G+        + +       + +VS+  S T+ S+ GSG  
Sbjct: 641  SETTTVSTTDSETTMVSTTGS-------ERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 1750
              S    +   V++ GSE  ++  +  G + +T   +        T+ S   +       
Sbjct: 694  TVSITGSETTKVSTTGSETTTTSTE--GSEITTASITGSETTTASTEGSETTTAST--EG 749

Query: 1751 GDCGSASMKPSQSASAICECTEAEAEIIL----QLKSELREKELKLTDIRLEALSSAHHL 1806
             +  SAS   S++ +A    +E     I+     + S +  +  K++    +  +     
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 1807 DQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSS 1855
             +   A         +  A ++ + A T  +   T   +E S +T++S+
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score =  104 bits (259), Expect = 1e-21
 Identities = 245/1206 (20%), Positives = 436/1206 (36%), Gaps = 142/1206 (11%)

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEG 373
            T   P A +  + +++    + ++ +K S T+T  T    +T  SPT S   +   +S  
Sbjct: 5    TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI-VSISGS 63

Query: 374  VKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
              T  S   S         + T         +  S  G +    S +G      S + S 
Sbjct: 64   EITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 434  GSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
             +TNS+   S       AGS+  +                  + V +E       D  T 
Sbjct: 124  TTTNSTTS-SETTVTSTAGSETTT-----------------VSTVGSETTTAYTADSETT 165

Query: 494  MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTAS 548
             A    S++ ++   GS       E++ PS++G     +   GS+  TV  T S  +TAS
Sbjct: 166  AASTTGSEMTTVFTAGS-------ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 218

Query: 549  KESEK--FRTTKGSPSQSLS---KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVA- 602
                +    +T GS +  +S      T+  A + +  A  E  E   A    S T T + 
Sbjct: 219  TAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAST 278

Query: 603  ---QSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYR-AHSENEGTALPSADSCTSPTKM 658
               +++  ST      +           +T+ P   + + + +E T + +A S T     
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 659  DLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFD 718
              S + T        +G +  T  +   +   D     E T +S  G++ + ++ E +  
Sbjct: 339  VGSETTTV-----STTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393

Query: 719  STVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSR 778
            +TV+T  +  T  ++T   T  T   G                       S       + 
Sbjct: 394  TTVSTTGSETTTVSITDSETTTTCTEG-----------------------SEMTAVSTTV 430

Query: 779  FMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINS 838
            F  TT     +   + + S  + +  ++   + ++    G         G    T   N+
Sbjct: 431  FETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTAS-NT 489

Query: 839  GYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNIS 898
            G  T     + + +     + + +  +   G    TV  +  ++++  ++G   T   +S
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT--TVS 547

Query: 899  TDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAG 958
            T  L TT++ +  S +T  S    +  TDS + S T                  +   AG
Sbjct: 548  TTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT-----------------TAASTAG 590

Query: 959  GKWKTVSSGLPED-PEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD 1017
             +  TVS+   E+         + S S TGS     S      +      S   T   TD
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 1018 DAKASEKGKAPLKGS-----SLQRSPSDAGKSSGDEGKKPPSGIGRSTAT-SSFGFKKPS 1071
                SE       GS     S + S +    ++G E      G G +T + +     K S
Sbjct: 651  ----SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVS 706

Query: 1072 GVGSSAMITSS-GATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSK 1130
              GS    TS+ G+ IT+ S T  +   ++  G ++      S +GS+         S+ 
Sbjct: 707  TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT---ASTEGSET-------TSAS 756

Query: 1131 TTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDS---NVSSKSAGATT--SKLREPTKIG 1185
            TT    +    + S T+     G   +  S+I S    VS+ S+  TT  ++  E T   
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1186 SGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIAS 1245
            +  S   TV+    E    + + SE+ + + +  S  T+AS  G++            AS
Sbjct: 817  TTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE---------TTTAS 867

Query: 1246 PTFRRLFGAKAGGKSASAPNTEG--VKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGG 1303
                    A   G   +  +TEG    ++S   S +TT + +GS  +  S TGS  +   
Sbjct: 868  TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927

Query: 1304 LSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY 1363
              GS +   +      T V +      +  A     T+   + +   ++S+AGS+ T   
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT-- 985

Query: 1364 QSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPK 1423
             S     T++ SI+      GS +   + T    + +  TG+  +T++ +   +  T+  
Sbjct: 986  VSTAGSETTTASIE------GSETTTVSSTGSETTTVSTTGT-ETTITSTEGSETTTVTT 1038

Query: 1424 KG-----LRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFS 1478
             G     +  T S       EG E     +TG    T + + L   + +S+S +G    S
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL-ETTTVSTSGSGTTTAS 1097

Query: 1479 NLVSPT 1484
               S T
Sbjct: 1098 TAGSET 1103



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 253/1247 (20%), Positives = 449/1247 (36%), Gaps = 139/1247 (11%)

Query: 345  STMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPS 404
            +T ++   S T T  T  S+      +    TA S   S   K     + T +      +
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSET 253

Query: 405  SGPS-DGGKDDDAFSESGEME-----GFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSN 458
            +  S +  + + AF+E  +       GF +   +  +T S P ++  +      +  +  
Sbjct: 254  TAASTEDSETNTAFTEDSKTTTASTTGFET--TAASTTGSEPTMASTMGSETTMASTIGP 311

Query: 459  KKSLLQPKEKE--------EKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGS 510
            + + +     E         +    + V +E          T  A    S+ ++    GS
Sbjct: 312  ETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGS 371

Query: 511  KTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
            +TT A  E    +++     GS+  TV  T S  +T S    +  TT    S+  +   T
Sbjct: 372  ETTTASTEGSETTTASTE--GSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT 429

Query: 571  MEKASASSCP------APLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSH 624
            + + + +S        A     E   AS  GS T TV  ++G  T        +    S+
Sbjct: 430  VFETTTASTEGSEITIASTSDSETTTASTEGSETTTVT-TAGSETKTAYTTGSETTTASN 488

Query: 625  PNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMR 684
                T   F   + +    T   S  +  S T  +++   T       +S    ET  + 
Sbjct: 489  TGLETTTVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS 547

Query: 685  TVKNIADLRQNLEETMSSLRG---TQISHSTLETTFDST-----------------VTTE 724
            T          LE T +S  G   T +S +  ETT DST                 V+T 
Sbjct: 548  TT--------GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA 599

Query: 725  VNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMY-TT 783
             +  T  +     T      G          + +  A    S T+    TD    M  TT
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 784  PLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKS---LRTDDINSGY 840
               R   S  G  S+        S+  +S+E   G   +   I G     + T    +  
Sbjct: 660  GSERTITSTEG--SETTTVSATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTT 714

Query: 841  MTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTD 900
             +  G  + T S+     T  S +    G    T   +  + +S+ ++G   T  + ++ 
Sbjct: 715  TSTEGSEITTASITGSETTTASTE----GSETTTASTEGSETTSASTTGSETTTASTTSS 770

Query: 901  DLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGK 960
            +    S + S + +       T   + +  + TT  T +S   +        +     G 
Sbjct: 771  ETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAG- 829

Query: 961  WKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG---APSRQKAGTSALKTPGK-- 1015
                S  +P     AG + + + S  GS     S +G      S + + T+   T G   
Sbjct: 830  ----SETIPAST--AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET 883

Query: 1016 -TDDAKASEKGKAPLKGSSLQRSPSDAGK-----SSGDEGKKPPSGIGRSTATSSFGFKK 1069
             T   + SE      +GS    + ++  +     ++G E     +    +T  S+ G + 
Sbjct: 884  TTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL 943

Query: 1070 P--SGVGSSAMITSSGATITSGSATLGKIPKSAAIGGK-----SNAGRKT---SLDGSQN 1119
               S  GS  +  S+  + T+   T+G    +A+  G      S AG +T   S++GS+ 
Sbjct: 944  TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 1120 QDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLR 1179
                V    S+TT    +    + +ST G        S T+++ +  S  +A  TT    
Sbjct: 1004 T--TVSSTGSETTTVSTTGTETTITSTEG--------SETTTVTTAGSETTAVYTTGS-- 1051

Query: 1180 EPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQ--PG 1237
            E T   +  S   TV+ T  E    + +D E+ ++S S  S  T+AS  G++       G
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSG-SGTTTASTAGSETTTVYITG 1110

Query: 1238 SKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMP--SPSTTLARQGSLESPSSGT 1295
            SK    ++        +    ++ +A +T G + ++V    S +TT++  GS  + SS  
Sbjct: 1111 SKTTTASTEGSEATTVSTTSSETTTA-STTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1296 GSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSA 1355
            GS  +     GS +   +     TT   +      ++  S     +     +   + SSA
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1229

Query: 1356 GSK--------------DTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLM 1401
            GS+               T S +   +  T SE+  + ++  G+ +  TT +     L  
Sbjct: 1230 GSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK 1289

Query: 1402 RTG-SVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEW---LRSHSTGG--LQDT 1455
             T  S++   +  M   R T    G R T SS       G ++     SH+  G  L  +
Sbjct: 1290 ATDVSIQPITNTPMSGTRTT----GTRLTASS-SVTMAPGMDFTASAASHTVPGIVLNTS 1344

Query: 1456 GNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSI 1502
            G  +  +  S+ +S+   +    +   PT+ S F   GP  M +N++
Sbjct: 1345 GLGTSTMGASSTTSAHGVRTTTGSTREPTS-STFQETGPVSMGTNTV 1390



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 218/1205 (18%), Positives = 416/1205 (34%), Gaps = 79/1205 (6%)

Query: 225  LAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKP 284
            + A   T ++ +G  T+   PT   G      + S S++   S     + + +S      
Sbjct: 30   IKASETTTASTAGSETTTPSPT---GSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTT 86

Query: 285  PNYANGNEKDSSKGPQSSSGVN--------GNVQPPSTAGQPPASAIPSPSASKPWRSKS 336
                 G+E   S     ++ V+         +     T      S+  + +++    + +
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 337  MNVKHSATSTMLTVKQSSTATSPTPSS-DRLKPPVSEGVKTAPSGQKSMLEKFKLVNART 395
            ++   S T+T  T    +TA S T S    +    SE +  + +G ++           T
Sbjct: 147  VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSET-------TTVST 199

Query: 396  ALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKN 455
            A       S+  S+      A SE+       S      +  S   VS   +   A S  
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTE 259

Query: 456  LSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAA 515
             S   +      K           T       +  +      +T+  +++ P+ +K + A
Sbjct: 260  DSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA 319

Query: 516  KKESLIPSSSG-----IPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPIT 570
              E     ++G         GS+  TV  T S  +TAS    +  T   + S++     T
Sbjct: 320  SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETT----T 375

Query: 571  MEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGN---GAVQLPQQQQHSHPNT 627
                 + +  A  EG EA   S +GS T TV+ +  ++T     G+             T
Sbjct: 376  ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 628  ATV--APFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRT 685
            A+   +     + S++E T   +  S T+      S +KTA     E +          T
Sbjct: 436  ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTT 495

Query: 686  VKNIAD-----LRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPM 740
            V  I         +  E T  S  G++++  + E + ++TV+T  +  T  + T   T  
Sbjct: 496  VFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTT 555

Query: 741  TWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQID 800
            T   G     +    A +       SGT+            +T       +   +     
Sbjct: 556  TSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS 615

Query: 801  MSEKASSDLDMSS-EVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRS----LNR 855
             S   S     S+   +     ++G        TD   +   T G     T +       
Sbjct: 616  ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTT 675

Query: 856  IPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNIT 915
            +  T +   +   G    TV     + +   ++G   T  +    ++ T S   S +   
Sbjct: 676  VSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735

Query: 916  VPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKA 975
                  T   +     +T+  T  S            +     G   T++S +  +  K 
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 976  GQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQ 1035
               +S   +         +++    S   + T+ + T G ++   AS  G      +S +
Sbjct: 796  STASSKMTTVFTE-----NSETTIASTTASETTTVSTAG-SETIPASTAGSETTTTTSTE 849

Query: 1036 RSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKP--SGVGSSAMITSSGATITSGSATL 1093
             S +    + G E     +    +T  ++ G +    S  GS    TS+  + T+ ++T 
Sbjct: 850  GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909

Query: 1094 GKIPKSAAIGGK-----SNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSG 1148
            G    + +  G      S  G +T+   ++  +   +  +   T+   +      S T+ 
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA----EGSETTT 965

Query: 1149 IPGRGGHRSSTSSIDSN---VSSKSAGATTSKLR--EPTKIGSGRSSPVTVNQTDKEKEK 1203
            +   G   ++ S+  S    VS+  +  TT+ +   E T + S  S   TV+ T  E   
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 1204 VAVSDSES--VSLSGSP---------KSSPTSASACGAQGLRQPGSKYPDIASPTFRRLF 1252
             +   SE+  V+ +GS          +++ TS        +   GS+    AS       
Sbjct: 1026 TSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSE-TTTASTADLETT 1084

Query: 1253 GAKAGGKSASAPNTEGVKSSSVM--PSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSP 1310
                 G   +  +T G ++++V    S +TT + +GS  +  S T S  +    +GS   
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144

Query: 1311 LFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLH 1370
                    TT V ++     +S A+    T+     +   ++S+AGS+ T +  + +   
Sbjct: 1145 TVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETT 1204

Query: 1371 TSSES 1375
            T+S S
Sbjct: 1205 TASTS 1209



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 171/889 (19%), Positives = 324/889 (36%), Gaps = 70/889 (7%)

Query: 999  APSRQKAGTSALKTPGKTDDA--KASEKGKAPLKGSSLQRSPSDAGKS------SGDEGK 1050
            AP+     T+A  T  +T     KASE   A   GS    +PS  G        SG E  
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT-TPSPTGSQTTIVSISGSEIT 66

Query: 1051 KPPSGIGRSTATSSFGF--KKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNA 1108
               +    +T  SS G      S  GS   ++++G+  T+ S T  +    +A+G ++  
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 1109 GRKTSLDGSQ-----NQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSID 1163
               TS + +      ++   V  V S+TT  Y +    + +ST+G        + + +I 
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 1164 SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES--VSLSGSPKSS 1221
             + +       ++   E T + +  S   T +    E    +   SE+  VS +GS  + 
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 1222 PTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS--SVMPSPS 1279
             T+ S   A       +   + A     +   A   G   +A +T G + +  S M S +
Sbjct: 247  STAGSETTAASTEDSET---NTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSET 303

Query: 1280 TTLARQG----SLESPSSGTGSMGSAGGLSGSSSPLFNKPSDL-TTDVISLSHSLASSPA 1334
            T  +  G     + + SS   ++ +AG  +  +S + ++ + + TT   + + S+  S  
Sbjct: 304  TMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTH 1394
            S  S T+G     A+   S   +  T   ++ T   T SE+  + ++     S  TT   
Sbjct: 364  STDS-TTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITD----SETTTTCT 418

Query: 1395 EVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQD 1454
            E   +   + +V  T + S +    T+       T ++     E          T     
Sbjct: 419  EGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYT 478

Query: 1455 TGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDD 1514
            TG+++   S + + ++           + T  S+      +     ++  + S       
Sbjct: 479  TGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVST 538

Query: 1515 SQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKL 1574
            +   GS T+       +S +G    +     GS ++ VS+T      AE    S +    
Sbjct: 539  T---GSETT------TVSTTG-LETTTTSTEGSEMTTVSTTG-----AETTTDSTEGSGT 583

Query: 1575 RRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELI----EL 1630
                 A  E     T+         A  E +  + TG   S T TA    SE      E 
Sbjct: 584  TAASTAGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEG 640

Query: 1631 RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 1690
             ET  +    +     +  G+        + +       + +VS+  S T+ S+ GSG  
Sbjct: 641  SETTTVSTTDSETTMVSTTGS-------ERTITSTEGSETTTVSATGSETTVSTEGSGTT 693

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNA 1750
              S    +   V++ GSE  ++  +  G + +T   +        T+ S   +       
Sbjct: 694  TVSITGSETTKVSTTGSETTTTSTE--GSEITTASITGSETTTASTEGSETTTAST--EG 749

Query: 1751 GDCGSASMKPSQSASAICECTEAEAEIIL----QLKSELREKELKLTDIRLEALSSAHHL 1806
             +  SAS   S++ +A    +E     I+     + S +  +  K++    +  +     
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 1807 DQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSS 1855
             +   A         +  A ++ + A T  +   T   +E S +T++S+
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 170/765 (22%), Positives = 289/765 (37%), Gaps = 50/765 (6%)

Query: 804  KASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSR 863
            K + D D  S  D     S+G+  G +   D+  S    D G      S +   D++ S 
Sbjct: 508  KGAEDDDSDSTSDTNNSDSNGN--GNNGNDDNDKS----DSGKGKSDSSDSDSSDSSNSS 561

Query: 864  DIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQ 923
            D         + D+   D S S SS  SD+ D+ S+D  ++ SS SS S+ +  S     
Sbjct: 562  D---------SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS----- 607

Query: 924  LRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSV 983
              +DS   S + ++ DS  +  K E D     D+  K  +  S   +  + +    S + 
Sbjct: 608  --SDSSDSSDSSDSSDSKSDSSKSESD---SSDSDSKSDSSDSNSSDSSDNSDSSDSSNS 662

Query: 984  SQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGK 1043
            S         S+     S     +S+  +   +D + +S+   +     S   S SD+  
Sbjct: 663  SN--------SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714

Query: 1044 SSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIG 1103
            SS             +++ SS          SS    SS ++ +S S+       S+   
Sbjct: 715  SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 774

Query: 1104 GKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSID 1163
              S++   +  + S N  D      S  +         S SS S         +S+ S +
Sbjct: 775  DSSDSSNSSDSNDSSNSSD------SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828

Query: 1164 SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPT 1223
            S+ SS S+ ++ S     +  GS   S    N++D      +   S+S + S S  SS +
Sbjct: 829  SSDSSDSSNSSDSSDSSDSSDGSDSDSS---NRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885

Query: 1224 SASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLA 1283
            + S+  +       S   D +  +      + +   S S+ ++E   SS    S  ++ +
Sbjct: 886  NESSNSSDSSDSSNSSDSDSSDSS----NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS 941

Query: 1284 RQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGG 1343
               S  S SS +    ++   S SS    +  SD ++D  + S S  SS +S  S +S  
Sbjct: 942  SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD-SSDSSNSSDSSDSSDSSDSSDSSDS 1000

Query: 1344 LVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRT 1403
               +++ S SS  S  + S  S  S  +S+ S     S     S  +  +    S     
Sbjct: 1001 SN-SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059

Query: 1404 GSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVS 1463
             S  S  S+S     ++        + SS  +N  +  +   S  +    D+ + S   S
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD-SS 1118

Query: 1464 PSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSATS 1523
             S+ SS ++     S+    +N S  +    S   S+S  + DSS D  D S    S+ S
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS-DSSDSSDSSDSSDS 1177

Query: 1524 LEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHS 1568
                  + S   S      +   SS S  SS SS  S + + + S
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1222



 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 210/1019 (20%), Positives = 368/1019 (36%), Gaps = 82/1019 (8%)

Query: 875  VDADSWDDSSSVSSGLSDTLDNIS-----TDDLNTTSSVSSYSNITVPSR---------K 920
            VD D    S   S+G+ +  DN S     T  LN   S    + IT  S          K
Sbjct: 317  VDGDKTSKSEENSAGIPE--DNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDK 374

Query: 921  NTQLRTDSE-KRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKA 979
              +++  S   R+ T E     E     +ED   HG   GK    + G   + E  GQK+
Sbjct: 375  GIEIKGPSSGNRNITKEVGKGNEG----KEDKGQHGMILGKGNVKTQGEVVNIEGPGQKS 430

Query: 980  SLSVSQTGSWRRGMSAQGGAPSRQKAGTSALK--TPGKTDDAKASEKGKAPLKGSSLQRS 1037
                ++ G    G  +             +++   P  +D++  ++   +    +S  R 
Sbjct: 431  EPG-NKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRG 489

Query: 1038 P----SDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATL 1093
                 SD  K +G+      +    S +TS       +G G++    +            
Sbjct: 490  DASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDND----------- 538

Query: 1094 GKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRG 1153
                KS +  GKS++    S D S + D      S  +     S    S S +S      
Sbjct: 539  ----KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594

Query: 1154 GHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVS 1213
               SS SS DS+ SS S+ ++ S     +K  S +S   + +   K       SDS S  
Sbjct: 595  SSDSSNSS-DSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDS----SDSNSSD 649

Query: 1214 LSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSS 1273
             S +  SS +S S+  +       S     +S +      + +   S S+ +++   SS 
Sbjct: 650  SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD 709

Query: 1274 VMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSP 1333
               S S+  +   S +S SS +     +   S SS    +  S  ++D    S+S  SS 
Sbjct: 710  SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769

Query: 1334 ASVHSFTSGGLVWA-ANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTG 1392
            +S  S +S     + +N SS+S+ S D+ +    ++   SS+S D   S   + S  +  
Sbjct: 770  SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS 829

Query: 1393 THEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRY-----TPSSRQANQEEGKEWLRSH 1447
            +    S      S  S  S+    D +              + SS  ++  +  +   S 
Sbjct: 830  SDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889

Query: 1448 STGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDS 1507
            ++    D+ N S   S S+ SS+++     SN    +  S  +    S   SNS  + DS
Sbjct: 890  NSSDSSDSSNSSD--SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDS 947

Query: 1508 SFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAH 1567
            S    D S    S+ S +    + S   +  DS +    SS S  SS SS  S + + + 
Sbjct: 948  S----DSSNSSDSSNSSDSSNSSDSSDSNSSDSSD----SSNSSDSSDSSDSSDSSDSSD 999

Query: 1568 SEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESEL 1627
            S            S +   +  S  S+N+           N +    S   +     S+ 
Sbjct: 1000 SSN----------SSDSSDSSDSSDSSNS-------SDSSNSSDSSNSSDSSDSSDSSDS 1042

Query: 1628 IELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGS 1687
             +  ++ +   + NS+  +    + +  D            SS+S  S NS+ S  S  S
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102

Query: 1688 GNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLP 1747
             + +DS      +  +   +   SS          +   S  SD  E +DSS  +     
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDS 1162

Query: 1748 HNAGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLD 1807
             ++ D  S S   S S+++      +++             +   +    ++  S+   D
Sbjct: 1163 SDSSD-SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1221

Query: 1808 QIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNN 1866
                + +   NE       +D   +   + +  +   S+S+S ++  S  QS   + NN
Sbjct: 1222 SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 198/1056 (18%), Positives = 366/1056 (34%), Gaps = 65/1056 (6%)

Query: 407  PSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPK 466
            PS  G D+D    SG+ E   +G     S NS  +             ++       +  
Sbjct: 246  PSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYY 305

Query: 467  EKEEKNRDKNKVCTEKPVKEEK--------------DQVTEMAPKKTSKIASLIPKGSKT 512
            + E K    N+V  +K  K E+              +   ++  +++ ++ + I K S+T
Sbjct: 306  DPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESET 365

Query: 513  TAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITME 572
             A  K         I  P S    + + +  G+   ++       KG     L K     
Sbjct: 366  HAVGKSQ--DKGIEIKGPSSGNRNITKEVGKGNEGKED-------KGQHGMILGKGNVKT 416

Query: 573  KASASSCPAPLEGREAGQAS-PSGSCTMTVAQSSGQSTGNGAVQLPQQQ-QHSHPNTATV 630
            +    +   P      GQ S P      +   S   S G  +     +  Q   PN++  
Sbjct: 417  QGEVVNIEGP------GQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDE 470

Query: 631  APFIYRAHSENEGTALPSAD-SCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKN- 688
            +     A+SE++  +    D S  S    D      +K   ++ S    +T    +  N 
Sbjct: 471  SNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNG 530

Query: 689  -----------------------IADLRQNLEETMSSLRGTQISHSTLET-TFDSTVTTE 724
                                    +D   + + + SS   +  S+S+ ++ + DS  +  
Sbjct: 531  NNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS 590

Query: 725  VNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTP 784
             +  +  +  S  +  +     +     + D+ S  +      +     +D S    +  
Sbjct: 591  SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS 650

Query: 785  LRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDG 844
               +  S   N S    S  +S   D SS  D        D    S  ++  +S   +D 
Sbjct: 651  SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710

Query: 845  GLNLYTRSLN-RIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLN 903
              +  + S N    D+ +S         + +  +DS D S+S  S  S    N S    +
Sbjct: 711  DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770

Query: 904  TTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKT 963
            + SS SS S+ +  S  ++     S+  +++D +  S         D DS   +     +
Sbjct: 771  SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830

Query: 964  VSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASE 1023
             SS      + +    S   S + S  R  S+     S     +++  +   +D  ++S 
Sbjct: 831  DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890

Query: 1024 KGKAPLKGSSLQRSPSDAGKSS--GDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITS 1081
               +    +S     SD+  SS   D      S    +++ +S      +   SS    S
Sbjct: 891  SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950

Query: 1082 SGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRP 1141
            S ++ +S S+       S+      ++    S D S + D      SS ++    S    
Sbjct: 951  SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1010

Query: 1142 SKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRS----SPVTVNQT 1197
              S +S          S++S DS+ SS S+ ++ S     +   S  S    S  + + +
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070

Query: 1198 DKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAG 1257
            D      +   SES   S S  SS +S S+  +       S     +S +      + + 
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130

Query: 1258 GKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSD 1317
              S S+ ++    SS    S  ++ +   S  S SS +     +   S SS    +  S 
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190

Query: 1318 LTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESID 1377
             ++D    S S  SS +S  S +S     +++ S SS  S    S  S  S  +S  S  
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSD-SSDSSDSSDSSDSNESSDSSDSSDSSDSSNS 1249

Query: 1378 LPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSES 1413
               S     S  T+ +++      ++G+  +  S+S
Sbjct: 1250 SDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS 1285



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 227/1117 (20%), Positives = 395/1117 (35%), Gaps = 154/1117 (13%)

Query: 789  AVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDG-DILGKSLRTDD----INSGYMTD 843
            A +R       D + +     D     DV     DG  + G +  TD+    I +    +
Sbjct: 148  ATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNE 207

Query: 844  GGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLN 903
            G  +  T  +N   +     ++      D  +D     D S   +G  +  D  S DD +
Sbjct: 208  GNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNS---DGSPSGNGADEDEDEGSGDDED 264

Query: 904  TTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSH----GDAGG 959
              +     S+     ++      + +  S+  +  DS +E   PE   D H    GD   
Sbjct: 265  EEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDS-KEYYDPEGKEDPHNEVDGDKTS 323

Query: 960  KWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDA 1019
            K +  S+G+PED        S  +  T       S +      +++ T A+   GK+ D 
Sbjct: 324  KSEENSAGIPED------NGSQRIEDTQKLNHRESKRVENRITKESETHAV---GKSQDK 374

Query: 1020 KASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMI 1079
                KG +    S  +    + GK  G+EGK+                      G   MI
Sbjct: 375  GIEIKGPS----SGNRNITKEVGK--GNEGKEDK--------------------GQHGMI 408

Query: 1080 TSSGATITSGSATLGKIPKSAAIGGKSNAGRKT--SLDGSQNQDDVVLHVSSKTTLQYRS 1137
               G   T G     + P     G KS  G K   S  GS +  D            Y S
Sbjct: 409  LGKGNVKTQGEVVNIEGP-----GQKSEPGNKVGHSNTGSDSNSD-----------GYDS 452

Query: 1138 LPRPSKSSTSGIPGRG----GHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVT 1193
                 KS     P       G+  + S  D+N SS+   +  S                 
Sbjct: 453  YDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNS----------------- 495

Query: 1194 VNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFG 1253
                D+ K+    SDS+      S  +S T+ S     G    G+   D  S + +    
Sbjct: 496  ----DESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNG--NNGNDDND-KSDSGKGKSD 548

Query: 1254 AKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFN 1313
            +     S S+ +++   SS    S S + +   S +S SS +    S+   + S S   +
Sbjct: 549  SSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS 608

Query: 1314 KPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSS 1373
              SD ++D    S S + S  S    +       ++ S+SS  S ++ S  S  S ++S 
Sbjct: 609  DSSD-SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSD 667

Query: 1374 ESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSR 1433
             S     S   S S  +  +    S      S  S  S+S   D +         +  S 
Sbjct: 668  SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727

Query: 1434 QANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPG 1493
             +N  +  +   S  +    D+ N S     S+ SS ++     S+    ++ S  +   
Sbjct: 728  SSNSSDSSDSSNSSDSSDSSDSSNSSD----SSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783

Query: 1494 PSMMRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVS 1553
             S   SNS  + DSS    + S    S+ S +    + S S +  DS      SS S  S
Sbjct: 784  DSNDSSNSSDSSDSS----NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS-SDSSDSSNS 838

Query: 1554 STSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRL 1613
            S SS  S + + + S+  ++       S    ++ +S  S +++   + + S  N +   
Sbjct: 839  SDSSDSSDSSDGSDSDSSNR-------SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891

Query: 1614 QSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESV 1673
               + ++   +S+  +   + +   + NS+  +    + N  D+           SS+S 
Sbjct: 892  SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE---SSNSSDNSNSSDSSNSSDSSDSS 948

Query: 1674 SSINSATSHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIE 1733
             S NS+ S +S  S N +DS      +  +S  S   S    +     S+   +S SD  
Sbjct: 949  DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS-SDSS 1007

Query: 1734 ELTDSSLPASPKLPHNAGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLT 1793
            + +DSS  ++     N+ D  ++S     S S+                           
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS--------------------------- 1040

Query: 1794 DIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSS 1853
                ++  S+   D    + +   ++       +D   +   + +  +   SESS S+ S
Sbjct: 1041 ----DSSDSSDSSDSSDSSNSSDSSD------SSDSSDSSDSSDSSDSSDSSESSDSSDS 1090

Query: 1854 SSSRQSLGLSLNNLNITEAVSSDILLDDAGDATGHKD 1890
            S+S  S   S ++ +   + SSD    D+ D++   D
Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSNSSD 1125



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 156/920 (16%), Positives = 311/920 (33%), Gaps = 74/920 (8%)

Query: 258  GSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQ 317
            GS S   G  + +   +S    D N     +NGN+  +S+   +SS   G+    S   +
Sbjct: 442  GSDSNSDGYDSYDFDDKSMQGDDPNSSDE-SNGNDDANSESDNNSSS-RGDASYNSDESK 499

Query: 318  PPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTA 377
               +   S  A              + ST  T    S       + D  K    +G   +
Sbjct: 500  DNGNGSDSKGAEDD----------DSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDS 549

Query: 378  PSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTN 437
                 S        N+  +       SS  +     D + S+S +    +S  +S  S+N
Sbjct: 550  SDSDSSDSS-----NSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD----SSDSDSSDSSN 600

Query: 438  SSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPK 497
            SS       +   + S + S+ KS     E +  + D     ++    +  D        
Sbjct: 601  SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660

Query: 498  KTSKIA----------SLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTA 547
             +S  +          S     S  ++   +S   S+S      S       + S  S+ 
Sbjct: 661  NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720

Query: 548  SKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSG--SCTMTVAQSS 605
            S  S+   +     S S +   + + + +S+     +  ++  +S S   S +   + SS
Sbjct: 721  SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 780

Query: 606  GQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKT 665
              S  N +         S+ + ++ +     +   ++  +  S+DS  S    D S S  
Sbjct: 781  NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840

Query: 666  AKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEV 725
            +    +   G D ++       N +D   + + + SS               DS+ +++ 
Sbjct: 841  SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS---------------DSSDSSDS 885

Query: 726  NGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPL 785
            N  +  + +S  +              + D+ S  +      +     +D S    ++  
Sbjct: 886  NESSNSSDSSDSS-------------NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932

Query: 786  RRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGG 845
              ++ S   + S        SSD   SS+       SD +    S  ++  +S   +D  
Sbjct: 933  SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992

Query: 846  LNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDS--SSVSSGLSDTLDNISTDDLN 903
             +  +   +   D++ S D         + D+ +  DS  SS SS  SD+ D+  + D +
Sbjct: 993  DSSDSSDSSNSSDSSDSSD---------SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043

Query: 904  TTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKT 963
             +S  S  S+ +  S  +    +DS   S + ++ DS +  +  +    S+         
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDS--SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101

Query: 964  VSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASE 1023
             S             +S S + + S     S+     S     + + ++   +D + +S+
Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161

Query: 1024 KGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSG 1083
               +     S   S S     S D      S     ++ SS          SS    SS 
Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1221

Query: 1084 ATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSK 1143
            ++ +S S+   +   S+     S++   +    S +  D     + ++  Q +S    + 
Sbjct: 1222 SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNN 1281

Query: 1144 SSTSGIPGRGGHRSSTSSID 1163
             S S     G   + ++S D
Sbjct: 1282 GSDSDSDSEGSDSNHSTSDD 1301



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 140/780 (17%), Positives = 278/780 (35%), Gaps = 53/780 (6%)

Query: 207  SPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGA 266
            S  S +S      D  SS ++   +  + +   +S    +     S   +   S   +  
Sbjct: 571  SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630

Query: 267  SNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSP 326
            S+ +      +S D N   +  N +  DSS    SS   +              S+  S 
Sbjct: 631  SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD--------------SSDSSD 676

Query: 327  SASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLE 386
            S+S    S S +   S+ S+  +    S+ +S + SSD      S+   +  S   S   
Sbjct: 677  SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS-----SDSSNSNSSDSDSSNS 731

Query: 387  KFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKL 446
                 ++ ++       SS  SD     D+ + S   +  +S  +S  S+NSS       
Sbjct: 732  SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS-DSSDSSNSSDSNDSSN 790

Query: 447  APPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLI 506
            +   + S N S+  +     +  + +   +   ++     +    +  +    S  +S  
Sbjct: 791  SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS-- 848

Query: 507  PKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLS 566
              GS + ++ +     SS       S   +     S  + +S  S+   ++  S S S  
Sbjct: 849  -DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907

Query: 567  KPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPN 626
               + + + +S+     E   +   S S S +   + SS  S  + +         S+ +
Sbjct: 908  SSNSSDSSDSSNSSDSSESSNSSDNSNS-SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966

Query: 627  TATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTV 686
             ++ +     + S N   +  S+DS  S    D S S  +       S +  ++      
Sbjct: 967  DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD-----SSDSSDSSNSSDS 1021

Query: 687  KNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQ 746
             N +D   + + + SS        S    + DS+ +++ +  +  + +S  +  +     
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS----D 1077

Query: 747  ACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKAS 806
            +    ++ D+         S +S    +  S             S   + S    S  +S
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDS-------------SDSSDSSDSSDSSNSS 1124

Query: 807  SDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDII 866
               D S   D     +  D    S  +D  +S   +D   +  +   +   D++ S D  
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184

Query: 867  QRGVHDVTVDADSWDDS--SSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQL 924
                   + D+    DS  SS SS  SD+ D+  + D ++ SS SS SN +  S  ++  
Sbjct: 1185 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD-SSDSSDSSDSNESSDSSDSSD- 1242

Query: 925  RTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVS 984
             +DS   S + ++ DS +      ++ DS   +G      ++G   D +  G  ++ S S
Sbjct: 1243 SSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSG---NGNNNGSDSDSDSEGSDSNHSTS 1299



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 83/473 (17%), Positives = 168/473 (35%), Gaps = 25/473 (5%)

Query: 206  ASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQG 265
            +S  S++S +    D   S  +  ++ S+ S  ++     +     S    +  SS    
Sbjct: 743  SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802

Query: 266  ASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPS 325
            +SN +  S S +S D +   +  + N  DSS    SS   + +    S+ G    S+  S
Sbjct: 803  SSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS---DSSDGSDSDSSNRS 859

Query: 326  PSASKPWRSKSMNVKHSA-TSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSM 384
             S++    S S +  +S+ +S      +SS ++  + SS+      S+   ++ S   S 
Sbjct: 860  DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 919

Query: 385  LEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSP 444
                   ++ ++       +S  SD     D+ S+S +    +   NS  S+NSS   S 
Sbjct: 920  -------SSDSSESSNSSDNSNSSDSSNSSDS-SDSSDSSNSSDSSNSSDSSNSSDS-SD 970

Query: 445  KLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIAS 504
              +   + S N S+        +  + +   N         +  D         +S  ++
Sbjct: 971  SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS-------SDSSDSSDSSDSSNSSDSSN 1023

Query: 505  LIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQS 564
                 + + ++       SS       S   +     S  S +S  S+   ++  S S  
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083

Query: 565  LSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSH 624
             S       +S SS     +  ++  +S S   + +   S   ++ + +           
Sbjct: 1084 SSDSSDSSNSSDSS-----DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138

Query: 625  PNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGED 677
             N++  +     + S +   +  S+DS  S    D S S  +    +     D
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1191



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 88/474 (18%), Positives = 168/474 (35%), Gaps = 38/474 (8%)

Query: 204  THASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKV 263
            +++S  S++S +    D   S  +  ++ S+ S  ++     +     S    + +SS  
Sbjct: 738  SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN---SSDSNDSSNSSDS 794

Query: 264  QGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAI 323
              +SN +  S S +S D +   +  + N  DSS    SS   N +    S+     +   
Sbjct: 795  SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS---DSSDSSDSSDGS 851

Query: 324  PSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKS 383
             S S++   RS S N   S+ S+      SS ++  + SSD      +E   ++ S   S
Sbjct: 852  DSDSSN---RSDSSNSSDSSDSS-----DSSNSSDSSDSSDS-----NESSNSSDSSDSS 898

Query: 384  MLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVS 443
                                SS  S+     D+ + S   E  NS  NS  S +S+   S
Sbjct: 899  --------------NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944

Query: 444  PKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIA 503
               +   + S + SN        +  + N   +   +      +    ++ +    S  +
Sbjct: 945  SD-SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003

Query: 504  SLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQ 563
            S     S ++ +   S   SS+      S   +     S  S +S  S+   ++  S S 
Sbjct: 1004 SDSSDSSDSSDSSNSS--DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061

Query: 564  SLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHS 623
              S       +S SS  +  +  E+  +S S + + +   S    + + +          
Sbjct: 1062 DSSDSSDSSDSSDSSDSS--DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119

Query: 624  HPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGED 677
              N++  +     + S +   +  S+DS  S    D S S  +    +     D
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSD 1173



 Score = 39.3 bits (90), Expect = 0.046
 Identities = 47/224 (20%), Positives = 88/224 (39%), Gaps = 15/224 (6%)

Query: 1670 SESVSSINSATSHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSH 1729
            S+S S  N++ S+ +  +GND + K    K   +S  S+   S   +     S    S  
Sbjct: 515  SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSS---DSSDSSDSDS 571

Query: 1730 SDIEELTDSSLPASPKLPHNAGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKE 1789
            SD    +DS    S     +  D  S S   S S+ +      +++      KS+  + E
Sbjct: 572  SDSNSSSDSDSSDSDSSDSSDSD-SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630

Query: 1790 LKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSS 1849
                       S +   D   ++ +   ++       +D   +   + +  +   S+SSS
Sbjct: 631  -----------SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679

Query: 1850 STSSSSSRQSLGLSLNNLNITEAVSSDILLDDAGDATGHKDGRS 1893
            S+ SS+S  S   S ++ +   + SSD    D+ D++   +  S
Sbjct: 680  SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 312/1473 (21%), Positives = 520/1473 (35%), Gaps = 200/1473 (13%)

Query: 205  HASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKP--TRLPGPSRVPAAGSSSK 262
            H+SP S A+         S ++    T  +  G   +   P  T  PG SR      SS 
Sbjct: 3610 HSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 3669

Query: 263  VQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQS--------------------- 301
                + L   S + +   +    ++++    D++  P S                     
Sbjct: 3670 GSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTH 3729

Query: 302  ---------SSG-VNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVK 351
                     SSG V  + +  S+ G P  +  P+ S S   + +S   +    ST  T  
Sbjct: 3730 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 3789

Query: 352  QSSTATSPTPSSDRL-KPPVSEGVKTAPSGQKSM--LEKFKLVNARTALRPPQPPSSGPS 408
              STAT+P   S    + P S      P+   +    EK  + ++        P S+  +
Sbjct: 3790 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 3849

Query: 409  DGGKDDDAFS-------ESGEMEGFNS--GLNSGGSTNSSPKVSP--KLAPPKAGSKNLS 457
              G+ +   S       E   + G  +  GL+   +T  S   SP   L+P    S  + 
Sbjct: 3850 TSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 3909

Query: 458  NKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKK 517
             + +  + +     +       T   + EE   V   +P  T    ++ P+ + T+  ++
Sbjct: 3910 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE--TTVFPRSTTTSVRRE 3967

Query: 518  ESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASAS 577
            E     S    +P S   T+    S  S  ++ES  F  +  S    L   +T       
Sbjct: 3968 EPTTFHS----RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE 4023

Query: 578  SCPAPLEGREAG-QASPSGSCTMTVAQSSGQS----TGNGAVQLPQQQQHSHPNTATVAP 632
            S   P      G + SP+ S T  +   S  S    +      LP     + P+ +  + 
Sbjct: 4024 STTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP--TTPSLSEKST 4081

Query: 633  FIYRAHSENEGTALP--------SADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMR 684
              Y +    + T  P        S +S TS ++   +++ TA       SG   E     
Sbjct: 4082 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT-TAFPDSTTTSGLSQEPTTSH 4140

Query: 685  TVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPN-LTSRPTPMTWR 743
            + +   +   +   T +S  G Q   +T  ++   T TT +   TI + L    TP    
Sbjct: 4141 SSQGSTEATLSPGSTTASSLGQQ--STTFHSSPGDTETTLLPDDTITSGLVEASTPTHSS 4198

Query: 744  LGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSE 803
             G     L    + S G    +  ++ F     S     +P    AV            E
Sbjct: 4199 TGSLHTTLTPASSTSTGL---QEESTTFQSWPSSSDTTPSPPSTTAVP----------VE 4245

Query: 804  KASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSR 863
             +++     S      + +    LG+S  +  ++S     G     TRS   +     + 
Sbjct: 4246 VSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 4305

Query: 864  DIIQRGVHDVTVDADSWDDSSSVSSGLSD--TLDNISTDDLNTTSSVSSYSNITVPSRKN 921
              I  G  + T         S+ ++GLS+  T    S    +TT S +S ++  V     
Sbjct: 4306 SPISSGSTETTA-----LPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 4360

Query: 922  TQLRTDSEKRSTTDETWDSPEELKKP---EEDFDSHGDAGGKWKTVSSGLPEDPEKAGQK 978
            T     S  R  +  T   P     P   +E   SH   G    T+S G        G +
Sbjct: 4361 T-----SHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPG-STTASSLGPE 4414

Query: 979  ASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSP 1038
            ++   S  GS    +       S     ++ + +   +     S  G    +G S   + 
Sbjct: 4415 STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGES---TT 4471

Query: 1039 SDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPK 1098
              +  +S D    PP      T TS+F     +  GS +  ++     ++ S TLG+  +
Sbjct: 4472 FQSWPNSKDTTPAPP------TTTSAFVELSTTSHGSPS--STPTTHFSASSTTLGRSEE 4523

Query: 1099 SAAIGGKSNAGRKT-----SLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRG 1153
            S  +     A   T     S      ++    H S  +T   +++  P  ++TSG     
Sbjct: 4524 STTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGST---QTMHFPESNTTSG----R 4576

Query: 1154 GHRSSTSSIDSNVSSKSAGATTSKL-REPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESV 1212
            G  S+TS   +  +  SA +TTS L  EPT   S   S  T +  D            S 
Sbjct: 4577 GEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPD------------SS 4624

Query: 1213 SLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS 1272
            + SG  + S  S S+  A G          I  P   R   +   G+S ++P + G   +
Sbjct: 4625 TTSGRSEESTASHSSQDATG---------TIVLPA--RSTTSVLLGESTTSPISSGSMET 4673

Query: 1273 SVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASS 1332
            + +P  +TT    G  E  ++   S  S      S+S      S+ +T V S   + A++
Sbjct: 4674 TALPGSTTT---PGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATT 4730

Query: 1333 PASVHSFTSGGLVWAANMSSSSAGSKDTPSY-QSMTSLHTSSES---------------- 1375
            P+   S TS GLV  +    SS GS  T  + +S T+   S ES                
Sbjct: 4731 PSPARSTTS-GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPS 4789

Query: 1376 -----IDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTP 1430
                 ++ P S+H S   + T TH  +S      S  ST S S   D N +      +T 
Sbjct: 4790 TTSALVEEPTSYHSSPGSIAT-THFPESSTTSGRSEESTASHSSP-DTNGITPLPAHFTT 4847

Query: 1431 SSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSA---AGKYHFSNLVSPTNLS 1487
            S R A      E    + + G  +T   S   +P   + S    +        +SP +++
Sbjct: 4848 SGRIA------ESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMT 4901

Query: 1488 QFNLPG-PSMMRS-------NSIPAQDSSFDLYDDSQLCGS---ATSLEERPRAISHSGS 1536
              ++ G P+ + S        + PA  ++  L  +S    S   +T     P +I+ S S
Sbjct: 4902 SSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTS-S 4960

Query: 1537 FRDSMEEVH---GSSLSLVSSTSSLYSTAEEKA 1566
            F       H   GS+LS VS  S+      E++
Sbjct: 4961 FAQEFTTPHSQPGSALSTVSPASTTVPGLSEES 4993



 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 272/1273 (21%), Positives = 452/1273 (35%), Gaps = 146/1273 (11%)

Query: 197  VELQQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKP--TRLPGPSRV 254
            V  +   +H+ P S  + A         L+    T  +  G   +   P  T   GPS+ 
Sbjct: 2547 VSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE 2606

Query: 255  PAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQS--SSG-VNGNVQP 311
                 SS     + L+  S +  S  +     +++     ++  P S  SSG V  + + 
Sbjct: 2607 STTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV 2666

Query: 312  PSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRL-KPPV 370
             S+ G P  +  P+ S S   + +S   +    ST  T    STAT+P   S    + P 
Sbjct: 2667 HSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG 2726

Query: 371  SEGVKTAPSGQKSM--LEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFS-------ESG 421
            S      P+   +    EK  + ++        P S+  +  G+ +   S       E  
Sbjct: 2727 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 2786

Query: 422  EMEGFNS--GLNSGGSTNSSPKVSP--KLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNK 477
             + G  +  GL+   +T  S   SP   L+P    S  +  + +  + +     +     
Sbjct: 2787 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2846

Query: 478  VCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTV 537
              T   + EE   V   +P  T    ++ P+ + T+   +E     S    +P S   T+
Sbjct: 2847 STTTPGLSEESTTVYSSSPGSTE--TTVFPRSTTTSVRGEEPTTFHS----RPASTHTTL 2900

Query: 538  KQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSC 597
                S  S  ++ES  F  +  S    L   +T       S   P         S SGS 
Sbjct: 2901 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFP---------SSSGST 2951

Query: 598  TMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATV------------APFIYRAHSENEGTA 645
              T++ +   ++G      P +   S   T T+            +   Y +    + T 
Sbjct: 2952 GTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 3011

Query: 646  LP--------SADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLE 697
             P        S +S TS ++   +++ TA       SG   E     + +   +   +  
Sbjct: 3012 SPATTTSSGVSEESSTSHSQPGSTHT-TAFPDSTTTSGLSQEPTASHSSQGSTEATLSPG 3070

Query: 698  ETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPN-LTSRPTPMTWRLGQACPRLQAGDA 756
             T +S  G Q   +T  ++   T TT +   TI + L    TP     G     L    A
Sbjct: 3071 STTASSLGQQ--STTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT--PA 3126

Query: 757  PSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVD 816
             S  AG     T+       S    + P   AA   +        S   ++    SS   
Sbjct: 3127 SSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTT- 3185

Query: 817  VGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVD 876
                      LG+S  +  ++S     G     TRS   +     +   I  G  + T  
Sbjct: 3186 ----------LGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTA- 3234

Query: 877  ADSWDDSSSVSSGLSD--TLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTT 934
                   S+ ++GLS+  T    S    +TT S +S ++  V     T     S  R  +
Sbjct: 3235 ----LPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTT-----SHSRPGS 3285

Query: 935  DETWDSPEELKKP---EEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRR 991
              T   P     P   +E   SH   G    T+S G        G +++   S  GS   
Sbjct: 3286 THTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPG-STTASSLGPESTTFHSGPGSTET 3344

Query: 992  GMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKK 1051
             +       S     ++ + +   +     S  G    +G S   +   +  +S D    
Sbjct: 3345 TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGES---TTFQSWPNSKDTTPA 3401

Query: 1052 PPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRK 1111
            PP      T TS+F     +  GS +  ++     ++ S TLG+  +S  +     A   
Sbjct: 3402 PP------TTTSAFVELSTTSHGSPS--STPTTHFSASSTTLGRSEESTTVHSSPVATAT 3453

Query: 1112 T-----SLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNV 1166
            T     S      ++    H S  +T   +++  P   +TSG     G  S+TS   +  
Sbjct: 3454 TPSPARSTTSGLVEESTTYHSSPGST---QTMHFPESDTTSG----RGEESTTSHSSTTH 3506

Query: 1167 SSKSAGATTSKL-REPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSA 1225
            +  SA +TTS L  EPT   S   S  T +  D            S + SG  + S  S 
Sbjct: 3507 TISSAPSTTSALVEEPTSYHSSPGSTATTHFPD------------SSTTSGRSEESTASH 3554

Query: 1226 SACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTT--LA 1283
            S+  A G          I  P   R   +   G+S ++P + G   ++ +P  +TT  L+
Sbjct: 3555 SSQDATG---------TIVLPA--RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLS 3603

Query: 1284 RQGSL--ESPSSGTGSMGSA----GGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVH 1337
             + +    SP S   ++  A     G+S  S+   ++P   +T   +   S  +   S H
Sbjct: 3604 EKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPG--STHTTAFPDSTTTPGLSRH 3661

Query: 1338 SFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQ 1397
            S TS     + + +   A +  + S Q  T+ H+SS S D  LS  GS + L+ G  E  
Sbjct: 3662 STTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALS-PGSTTALSFG-QEST 3719

Query: 1398 SLLMRTGSVRSTL 1410
            +     GS  +TL
Sbjct: 3720 TFHSSPGSTHTTL 3732



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 311/1466 (21%), Positives = 517/1466 (35%), Gaps = 170/1466 (11%)

Query: 200  QQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQK---KPTRLPGPSRVPA 256
            ++  T  S P             +   +R++T S+ S  +T        T   GPS+   
Sbjct: 992  EESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST 1051

Query: 257  AGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQS--SSG-VNGNVQPPS 313
               SS     + L+  S +  S  +     ++N     ++  P S  SSG V  + +  S
Sbjct: 1052 TSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHS 1111

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRL-KPPVSE 372
            + G P  +  P+ S S   + +S   +    ST  T    STAT+P   S    + P S 
Sbjct: 1112 STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 1171

Query: 373  GVKTAPSGQKSM--LEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFS-------ESGEM 423
                 P+   +    EK  + ++        P S+  +  G+ +   S       E   +
Sbjct: 1172 PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTL 1231

Query: 424  EGFNS--GLNSGGSTNSSPKVSPKLAPPKAGSKNLS-NKKSLLQPKEKEEKNRDKNKVCT 480
             G  +  GL+   +T  S   SP      A   +L   ++S     +    +   +   T
Sbjct: 1232 PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAST 1291

Query: 481  EKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQT 540
              P   E +  T  +  + S   ++ P  + T+   +E     S    +P S   T+   
Sbjct: 1292 TTPGLSE-ESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHS----RPASTHTTL--- 1343

Query: 541  ISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQAS---PSGSC 597
             +  ST S  +E+     GSP+           ++ +  PA L   + G+ S   PS S 
Sbjct: 1344 FTEDSTTSGLTEESTAFPGSPA-----------STQTGLPATLTTADLGEESTTFPSSSG 1392

Query: 598  TMTVAQSSGQSTGNGAV--QLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSP 655
            +     S  +ST +G V    P +   S   T T+              +  S    TSP
Sbjct: 1393 STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLP-----GSPTTPSLSEKSTTFYTSP 1447

Query: 656  TKMDLSYS---KTAKQCLEEISGEDPETRRMRTV-----KNIADLRQNLEETMSSLRGTQ 707
               D + S    T+    EE S    +     T         +DL Q    + SS   T+
Sbjct: 1448 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTE 1507

Query: 708  ISHSTLETTFDSTVTTEVNGRTIPNLTSR----PTPMTWRLGQACPRLQAGDAPSLGAGY 763
             + S   TT  S         + P  T         +T  L +A     +          
Sbjct: 1508 ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 1567

Query: 764  PRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSD 823
            P S TS  +  + + F           S  G  +     E +++     S      + + 
Sbjct: 1568 PASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAA--PVEVSTTYHSRPSSTPTTHFSAS 1625

Query: 824  GDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDS 883
               LG+S  +  ++S     G     TRS   +     +   I  G  + T         
Sbjct: 1626 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTA-----LPG 1680

Query: 884  SSVSSGLSD--TLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSP 941
            S+ ++GLS+  T    S    +TT S +S ++  V     T     S  R  +  T   P
Sbjct: 1681 STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTT-----SHSRPGSTHTTAFP 1735

Query: 942  EELKKP---EEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG 998
                 P   +E   SH   G    T+S G        G +++   S  GS    +     
Sbjct: 1736 GSTTMPGVSQESTASHSSPGSTDTTLSPG-STTASSLGPESTTFHSSPGSTETTLLPDNT 1794

Query: 999  APSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGR 1058
              S     ++ + +   +     S  G    +G S   +   +  SS D    PP     
Sbjct: 1795 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGES---TTFQSWPSSKDTMPAPP----- 1846

Query: 1059 STATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQ 1118
             T TS+F     +  GS +  ++     ++ S TLG+  +S  +     A   T      
Sbjct: 1847 -TTTSAFVELSTTSHGSPS--STPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARS 1903

Query: 1119 NQDDVV----LHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSA--- 1171
                +V     + SS  + Q    P  S +S      R  H S+T +I S  S+ SA   
Sbjct: 1904 TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVE 1963

Query: 1172 ---------GATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVS--LSGSPKS 1220
                     G+T +     +   SGRS   T + + ++     V  + S +  L G   +
Sbjct: 1964 EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT 2023

Query: 1221 SPTSASACGAQGLRQPGS-KYPDIA--SPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPS 1277
            SP S+ +     L  PGS   P ++  S TF     + A   S ++  + GV   S    
Sbjct: 2024 SPISSGSMETTAL--PGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEES---- 2077

Query: 1278 PSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVH 1337
             +T+ +R GS  + +    +  +  GLS  S+   + P   +TD   L  S  +S  S  
Sbjct: 2078 -TTSHSRPGSTHTTAFPDST--TTPGLSRHSTTSHSSPG--STDTTLLPASTTTSGPSQE 2132

Query: 1338 SFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSL-SGLTTGTHEV 1396
            S TS     + + + S   +      Q  T+ H+S  S    L    +  SG+   +  V
Sbjct: 2133 STTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV 2192

Query: 1397 QSLLMRTGSVRSTLS-----------ESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLR 1445
             S    TGS R+TLS           ES     +          PS+  A  EE   + R
Sbjct: 2193 HS---STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 2249

Query: 1446 ------------SHSTGGLQDTG---NQSPLVS---PSAMSSSAAGK-YHFSNLVSPTNL 1486
                        S +T G  +     + SP  S   PS+  S+ +G+    ++ +SP + 
Sbjct: 2250 SPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGST 2309

Query: 1487 SQFNLPGPSMMRSNSIPA-QDSSFDLYDDSQ------LCGSATSL---EERPRAISHSGS 1536
                LPG     S + P   ++S   Y   +         S TSL   EE   + S  GS
Sbjct: 2310 EITTLPG-----STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS 2364

Query: 1537 FRDSMEEVHGSSLSLVSSTSSLYSTA 1562
               ++     ++  L   ++++YS++
Sbjct: 2365 THSTVSPASTTTPGLSEESTTVYSSS 2390



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 288/1329 (21%), Positives = 487/1329 (36%), Gaps = 196/1329 (14%)

Query: 301  SSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPT 360
            SSSG  G    P+ +         +PS   P  +++  +  S T+  L+ K ++  TSP 
Sbjct: 2472 SSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR 2531

Query: 361  PSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSES 420
                 L P       T  SG          V+  ++    QP       G     AF +S
Sbjct: 2532 SPDATLSP-----ATTTSSG----------VSEESSTSHSQP-------GSTHTTAFPDS 2569

Query: 421  GEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCT 480
                G +       +++SSP  +     P + + +  +++S          +   +   T
Sbjct: 2570 TTTPGLS---RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGST 2626

Query: 481  EKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESL-IPSSSGIPKPGSKVPTVKQ 539
                  ++      +P  T    +L P  + ++   + S  + SS+G P         + 
Sbjct: 2627 TALSFGQESTTFHSSPGSTH--TTLFPDSTTSSGIVEASTRVHSSTGSP---------RT 2675

Query: 540  TISPGSTASK----ESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSG 595
            T+SP S+ S     ES  F+T   S   + S P        S+  AP+E       SP G
Sbjct: 2676 TLSPASSTSPGLQGESTTFQTHPASTHTTPSPP--------STATAPVEESTTYHRSP-G 2726

Query: 596  SCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSP 655
            S   T   +S  ++G+          HS P+ +   P    AHS   G    S  S  SP
Sbjct: 2727 STPTTHFPASSTTSGHSE---KSTIFHSSPDASGTTP--SSAHSTTSGRG-ESTTSRISP 2780

Query: 656  --TKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNL---EETMSSLRGTQISH 710
              T++      T    L E S     + R  T         +L   EE+ +S      +H
Sbjct: 2781 GSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTH 2840

Query: 711  STLETTFDSTVTTEVNGRTIPNLTSRP-TPMTWRLGQACPRLQAGDAPSLGAGYPRSGTS 769
            ST+     ST T  ++  +    +S P +  T    ++      G+ P+     P S T 
Sbjct: 2841 STVSPA--STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPAS-TH 2897

Query: 770  RFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKA---SSDLDMSSEVDVGGYMSDGDI 826
              + T+ S    T+ L   + +  G+ +       A   ++DL   S        S G  
Sbjct: 2898 TTLFTEDST---TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTT 2954

Query: 827  LGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDAD---SWDDS 883
            L  +  T     G  T   L+  +     +P + T+  + ++     T       +   +
Sbjct: 2955 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 3014

Query: 884  SSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWD--SP 941
            ++ SSG+S+  ++ ++     ++  +++ + T  S  + +       + +T+ T    S 
Sbjct: 3015 TTTSSGVSE--ESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGST 3072

Query: 942  EELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAG--QKASLSVSQTGSWRRGMSAQGGA 999
                  ++    H   G    T ++ LP+D   +G  + ++ + S TGS    ++     
Sbjct: 3073 TASSLGQQSTTFHSSPG---DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASST 3129

Query: 1000 PSRQKAGTSALKTPGKTDDAKASEKG--KAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIG 1057
             +  +  ++  ++   + D   S  G   AP++ S+   S   +  ++        + +G
Sbjct: 3130 SAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASS--TTLG 3187

Query: 1058 RSTATSSFGFKKPSGVGSSAMITSSGATITSGSATL-----GKIPKSAAIGGKSNAG--- 1109
            RS  +++     P   G++   T S  ++  G  T      G    +A  G  + AG   
Sbjct: 3188 RSEESTTV-HSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSE 3246

Query: 1110 RKTSLDGSQNQDDVVLHVSSKTTL-----QYRSLPRPSKSSTSGIPGR----GGHRSST- 1159
            + T+   S    D  L  +S T+         S  RP  + T+  PG     G  + ST 
Sbjct: 3247 KSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTA 3306

Query: 1160 --SSIDSNVSSKSAGATTSKLREP--TKIGSGRSSPVTVNQTDKEKEKVAVSDSESV-SL 1214
              SS  S  ++ S G+TT+    P  T   SG  S  T    D       +  S  V S 
Sbjct: 3307 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSS 3366

Query: 1215 SGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSV 1274
            +GSP ++ + A +   QG            S TF+            S PN     S   
Sbjct: 3367 TGSPHTTLSPAGSTTRQG-----------ESTTFQ------------SWPN-----SKDT 3398

Query: 1275 MPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPA 1334
             P+P TT +    L + S G+ S       S SS+ L    S+ +T V S   + A++P+
Sbjct: 3399 TPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR--SEESTTVHSSPVATATTPS 3456

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSY----------QSMTSLH------------TS 1372
               S TS GLV  +    SS GS  T  +          +  T+ H            T+
Sbjct: 3457 PARSTTS-GLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTT 3515

Query: 1373 SESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSS 1432
            S  ++ P S+H S  G T  TH   S      S  ST S S Q    T+        P+ 
Sbjct: 3516 SALVEEPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI------VLPAR 3568

Query: 1433 RQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLP 1492
               +   G+      S+G ++ T       +P     S    +H S     T LS     
Sbjct: 3569 STTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT--FHSSPRSPATTLS----- 3621

Query: 1493 GPSMMRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLV 1552
                      PA  +S  + ++S      T+   RP + +H+ +F DS     G S    
Sbjct: 3622 ----------PASTTSSGVSEES------TTSHSRPGS-THTTAFPDS-TTTPGLSRHST 3663

Query: 1553 SSTSSLYST 1561
            +S SS  ST
Sbjct: 3664 TSHSSPGST 3672



 Score = 89.0 bits (219), Expect = 5e-17
 Identities = 316/1427 (22%), Positives = 504/1427 (35%), Gaps = 219/1427 (15%)

Query: 204  THASPPSEA-SQAKTQQDMQSSLAARYAT----QSNHSGIATSQKKPTRLPGPSRVPAAG 258
            TH S  S    +++    + SS  A   T    +S  SG+          PG ++     
Sbjct: 1869 THFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFP 1928

Query: 259  SSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQP 318
             SS   G S  +R S S  +   + PP                 S  +  V+ P++    
Sbjct: 1929 ESSTASGRSEESRTSHSSTTHTISSPP-----------------STTSALVEEPTSYHSS 1971

Query: 319  PASAIPS---PSASKPWRSKSMNVKHS---ATSTMLTVKQSSTA-------TSPTPSSDR 365
            P S   +    S++   RS+     HS   AT T++   +S+T+       TSP  SS  
Sbjct: 1972 PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPI-SSGS 2030

Query: 366  LKPPVSEGVKTAPS-GQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEME 424
            ++     G  T P   +KS        +  T L P    SSG S+      +   S    
Sbjct: 2031 METTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTT 2090

Query: 425  GFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPV 484
             F     + G +  S   +   + P +    L    +      +E      +   T+  +
Sbjct: 2091 AFPDSTTTPGLSRHS---TTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTAL 2147

Query: 485  KEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTV----KQT 540
                        + T+  +S    GS  T    +S   +SSGI +  ++V +     + T
Sbjct: 2148 SPGSTTALSFGQESTTFHSS---PGSTHTTLFPDST--TSSGIVEASTRVHSSTGSPRTT 2202

Query: 541  ISPGSTASK----ESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGS 596
            +SP S+ S     ES  F+T   S   + S P        S+  AP+E       SP GS
Sbjct: 2203 LSPASSTSPGLQGESTAFQTHPASTHTTPSPP--------STATAPVEESTTYHRSP-GS 2253

Query: 597  CTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEG------------- 643
               T   +S  ++G+          HS P+ +   P    AHS   G             
Sbjct: 2254 TPTTHFPASSTTSGHSE---KSTIFHSSPDASGTTPS--SAHSTTSGRGESTTSRISPGS 2308

Query: 644  ---TALPSADSCTSPTKMDLSYSKTAKQCLEEIS---------GEDPETRRMR------T 685
               T LP + +    ++   ++  + +     +S         GE+  T R +      T
Sbjct: 2309 TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHST 2368

Query: 686  VKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRL- 744
            V   +     L E  +++  +    ST  T F  T TT V G       SRP      L 
Sbjct: 2369 VSPASTTTPGLSEESTTVYSSSPG-STETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLF 2427

Query: 745  ------------GQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSR 792
                          A P    G   S   G P + T+  +  + + F  ++      +S 
Sbjct: 2428 TEDSTTSGLTEESTAFP----GSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSP 2483

Query: 793  LGNMSQIDMSEKASSDLDMSS--EVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYT 850
              + +   + E   S L  SS     + G  +   +  KS  T    S    D  L+  T
Sbjct: 2484 ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPAT 2541

Query: 851  RSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLS--DTLDNISTDDLNTTSSV 908
             + + + +  +S    Q G    T   D     S+ + GLS   T  + S    +TT   
Sbjct: 2542 TTSSGVSE-ESSTSHSQPGSTHTTAFPD-----STTTPGLSRHSTTSHSSPGSTDTTLLP 2595

Query: 909  SSYSNITVPSRKNTQLRTDSEKRSTTDETWD--SPEELKKPEEDFDSHGDAGGKWKTVSS 966
            +S +  + PS+++T   T      +TD      S   L   +E    H   G    T+  
Sbjct: 2596 AS-TTTSGPSQEST---TSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL-- 2649

Query: 967  GLPEDPEKAG-QKASLSV-SQTGSWRRGMS-AQGGAPSRQKAGTSALKTPGKTDDAKA-S 1022
              P+    +G  +AS  V S TGS R  +S A   +P  Q   T+    P  T    +  
Sbjct: 2650 -FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPP 2708

Query: 1023 EKGKAPLKGS-SLQRSPSDA-----GKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSS 1076
                AP++ S +  RSP          SS   G    S I  S+  +S      +   +S
Sbjct: 2709 STATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTS 2768

Query: 1077 AMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTL--- 1133
                S+ + I+ GS  +  +P S    G S A   T+   S       L  +S T+L   
Sbjct: 2769 GRGESTTSRISPGSTEITTLPGSTTTPGLSEA--STTFYSSPRSPTTTLSPASMTSLGVG 2826

Query: 1134 ----QYRSLP-------RPSKSSTSGIPGRGG--HRSSTSSIDSNVSSKSAGATTSKLRE 1180
                  RS P        P+ ++T G+       + SS  S ++ V  +S   T+ +  E
Sbjct: 2827 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRST-TTSVRGEE 2885

Query: 1181 PTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKY 1240
            PT   S  +S  T   T  E    +    ES +  GSP S+ T   A             
Sbjct: 2886 PTTFHSRPASTHTTLFT--EDSTTSGLTEESTAFPGSPASTQTGLPA------------- 2930

Query: 1241 PDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGS 1300
                      L  A  G +S + P++ G   +++ P+ STT    G   +PS  + S   
Sbjct: 2931 ---------TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGE-STPSRLSPSSTE 2980

Query: 1301 AGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDT 1360
               L GS +         T      S     SPA+    TS G+   ++ S S  GS  T
Sbjct: 2981 TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT---TSSGVSEESSTSHSQPGSTHT 3037

Query: 1361 PSY----------QSMTSLHTSSESIDLPLS----HHGSLSGLTTGTH----EVQSLLMR 1402
             ++          Q  T+ H+S  S +  LS       SL   +T  H    + ++ L+ 
Sbjct: 3038 TAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 3097

Query: 1403 TGSVRSTLSESMQLDRNTLPKKGLRYTP-SSRQANQEEGKEWLRSHSTGGLQDTGNQSPL 1461
              ++ S L E+     ++        TP SS  A  +E     +S  +    DT    P 
Sbjct: 3098 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSS--SDTTPSPPG 3155

Query: 1462 VSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSS 1508
             + + +  S    YH     +PT  + F+    ++ RS       SS
Sbjct: 3156 TTAAPVEVSTT--YHSRPSSTPT--THFSASSTTLGRSEESTTVHSS 3198



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 289/1311 (22%), Positives = 450/1311 (34%), Gaps = 194/1311 (14%)

Query: 232  QSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGN 291
            ++  SG++         PGP+   A   S+ + G S   + S + +SI  +     + G 
Sbjct: 298  RTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS---QESTASHSIPGSTDTTLSPGT 354

Query: 292  EKDSSKGPQ-----SSSGVNGNVQPP---STAGQPPASAIPSPSASKPWR--SKSMNVKH 341
               SS GP+     SS G     + P   +T+G   AS     S   P    S S +  H
Sbjct: 355  TTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTH 414

Query: 342  SATSTMLTVKQSSTATSPTPSSD-----RLKPPVSEGVKTAPSGQKSML--------EKF 388
                T      SS  TSP PS       +L         + P+   S          E  
Sbjct: 415  EGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEEST 474

Query: 389  KLVNARTALRPPQPPSSGPSDGGKDDDA-------------FSESGEMEGFN-SGLNSGG 434
             + ++  A     PP+   + G  ++               F ES    G +       G
Sbjct: 475  PVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHG 534

Query: 435  STNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEM 494
            ST  +   +P      A +   S+  S      +    RD + +      + E+ + +  
Sbjct: 535  STTHTKSSTPSTTAALAHTSYHSSLGS-----TETTHFRDSSTISG----RSEESKASHS 585

Query: 495  APKKTSKIASLIPKGSKTTAAKKESL-IPSSSGIPK----PGSKVPTVKQTISPGSTASK 549
            +P   +   +++P GS  +    +S   P SSG  +    PGS   T K  +S  ST   
Sbjct: 586  SP--DAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGS---TTKPGLSEKSTTFY 640

Query: 550  ESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQST 609
             S +   T   P+   S  ++ E  ++ S P    G     A P GS TM          
Sbjct: 641  SSPRSPDTTHLPASMTSSGVSEESTTSHSRP----GSTHTTAFP-GSTTMP--------- 686

Query: 610  GNGAVQLPQQQQHSH----PNTATVAPFIYRAHSEN-EGTALPSADSCTSPTKMDLSYSK 664
                  L Q+   SH    P   T++P    A S   E T   S    T  T   L  + 
Sbjct: 687  -----GLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTL--LPDNT 739

Query: 665  TAKQCLEEISGEDPETRRMRTVKNIA--DLRQNLEETMSSLRGTQISHSTLETT----FD 718
            TA   LE        TR   T  + A    RQ    T  S   ++ +     TT     +
Sbjct: 740  TASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVE 799

Query: 719  STVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGT-------SRF 771
             + T+  +  +IP         T  L +      +    +    +P S T       S  
Sbjct: 800  PSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT 859

Query: 772  IHTDPSRFMYTTPLRRAAV--------SRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSD 823
             H+  +  + + P   +A+        S  G+ +     +  SS     SE     + S 
Sbjct: 860  SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPD--SSTTSGRSEESTASHSSQ 917

Query: 824  ---GDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGV---HDVTVDA 877
               G I+  +  T  +  G  T   ++  +     +P + T+  + +R           A
Sbjct: 918  DATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPA 977

Query: 878  DSWDDSSSVSSGLSD---------------------TLDNISTDDLNTTSSVSSYSNITV 916
             +   +S+ SSG+S+                     T   +S     + SS  S     +
Sbjct: 978  TTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL 1037

Query: 917  PSRKNT----QLRTDSEKRSTTDETWDSP---EELKKPEEDFDSHGDAGGKWKTVSSGLP 969
            P+   T    Q  T S   S + +T  SP     L   +E    H + G    T+    P
Sbjct: 1038 PASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL---FP 1094

Query: 970  EDPEKAG-QKASLSV-SQTGSWRRGMS-AQGGAPSRQKAGTSALKTPGKTDDAKA-SEKG 1025
            +    +G  +AS  V S TGS R  +S A   +P  Q   T+    P  T    +     
Sbjct: 1095 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 1154

Query: 1026 KAPLKGS-SLQRSPSDA-----GKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMI 1079
             AP++ S +  RSP          SS   G    S I  S+  +S      +   +S   
Sbjct: 1155 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 1214

Query: 1080 TSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLP 1139
             S+ + I+ GS  +  +P S    G S A   T+   S       L  +S T     SL 
Sbjct: 1215 ESTTSRISPGSTEITTLPGSTTTPGLSEA--STTFYSSPRSPTTTLSPASMT-----SLG 1267

Query: 1140 RPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDK 1199
               +S+TS        RS   S  S VS   A  TT  L E +      S   T      
Sbjct: 1268 VGEESTTS--------RSQPGSTHSTVS--PASTTTPGLSEESTTVYSSSRGSTETTVFP 1317

Query: 1200 EKEKVAVSDSESVSLSGSPKSSPTS--ASACGAQGLRQPGSKYPDIASPTF----RRLFG 1253
                 +V   E  +    P S+ T+         GL +  + +P   + T       L  
Sbjct: 1318 HSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 1377

Query: 1254 AKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFN 1313
            A  G +S + P++ G   + + P+ STT           SG     +   LS SS+    
Sbjct: 1378 ADLGEESTTFPSSSGSTGTKLSPARSTT-----------SGLVGESTPSRLSPSSTETTT 1426

Query: 1314 KPSDLTTDVIS-LSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTS 1372
             P   TT  +S  S +  +SP S  +  S     ++ +S  S+ S   P     T+   S
Sbjct: 1427 LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS 1486

Query: 1373 SESIDL---PLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNT 1420
            + + DL   P + H S  G T  T    S    +   +ST   S   D  T
Sbjct: 1487 TTTSDLSQEPTTSHSS-QGSTEATLSPGSTTASSLGQQSTTFHSSPGDTET 1536



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 299/1412 (21%), Positives = 477/1412 (33%), Gaps = 211/1412 (14%)

Query: 203  VTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSK 262
            + H+SP +  +   T     S+ + R   +S  S I+    + T LPG +  P       
Sbjct: 2748 IFHSSPDASGT---TPSSAHSTTSGR--GESTTSRISPGSTEITTLPGSTTTPG------ 2796

Query: 263  VQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASA 322
                  L+  S +F S  ++     +  +      G +S++  +   QP ST      S 
Sbjct: 2797 ------LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS---QPGSTH-----ST 2842

Query: 323  IPSPSASKPWRSKSMNVKHSAT--STMLTVKQSSTATS---PTPSSDRLKPPVSEGVKTA 377
            +   S + P  S+     +S++  ST  TV   ST TS     P++   +P  +      
Sbjct: 2843 VSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFT 2902

Query: 378  PSGQKSML--EKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGS 435
                 S L  E      +  + +   P +   +D G++   F  S    G  + L+   S
Sbjct: 2903 EDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTG--TTLSPARS 2960

Query: 436  TNSS---PKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEK--NRDKNKVCTEKPVKEEKDQ 490
            T S         +L+P    +  L    +     EK        ++   T  P       
Sbjct: 2961 TTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSG 3020

Query: 491  VTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPG-SKVPTVKQTISPGSTAS- 548
            V+E +    S+     P  + TTA    +     S  P    S   + + T+SPGST + 
Sbjct: 3021 VSEESSTSHSQ-----PGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTAS 3075

Query: 549  ---KESEKFRTTKGSPSQSL-------------SKPITMEKASASSCPAPLEGREAGQAS 592
               ++S  F ++ G    +L             S P      S  +   P     AG   
Sbjct: 3076 SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQE 3135

Query: 593  PSGSCTMTVAQSSGQSTGNGAVQLPQQQQ---HSHPNTATVAPFIYRAHS---ENEGTAL 646
             S +     + S    +  G    P +     HS P++     F   + +     E T +
Sbjct: 3136 ESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTV 3195

Query: 647  PSADSCTS----PTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSS 702
             S+   T     PT+   S     +     IS    ET  +      A L +      SS
Sbjct: 3196 HSSPGATGTALFPTRSATSVL-VGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 3254

Query: 703  LRGTQISHSTLETTFD--------------STVTTEVNGRT-IPNLTSRPTPMTWRLGQA 747
             R    + S   TT                ST TT   G T +P ++   T      G  
Sbjct: 3255 PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGST 3314

Query: 748  CPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASS 807
               L  G   +   G P S T    H+ P     T                +  +  AS 
Sbjct: 3315 DTTLSPGSTTASSLG-PESTT---FHSGPGSTETTL---------------LPDNTTASG 3355

Query: 808  DLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQ 867
             L+ S+ V    + S G     S  T    +G  T  G +   +S     DT  +     
Sbjct: 3356 LLEASTPV----HSSTG-----SPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTT 3406

Query: 868  RGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTD 927
                +++  +     SS+ ++  S +   +   + +TT   S  +  T PS   +     
Sbjct: 3407 SAFVELSTTSHG-SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGL 3465

Query: 928  SEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVS---------------SGLPEDP 972
             E+ +T   +  S + +  PE D  S     G+  T S               S L E+P
Sbjct: 3466 VEESTTYHSSPGSTQTMHFPESDTTS---GRGEESTTSHSSTTHTISSAPSTTSALVEEP 3522

Query: 973  ----EKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGK-TDDAKASEKGKA 1027
                   G  A+     + S   G S +  A    +  T  +  P + T      E   +
Sbjct: 3523 TSYHSSPGSTATTHFPDS-STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 3581

Query: 1028 PLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATIT 1087
            P+   S++        ++   G     G+   + T     + P+   S A  TSSG +  
Sbjct: 3582 PISSGSME--------TTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEE 3633

Query: 1088 S-------GSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPR 1140
            S       GS      P S    G S     T+   S    D  L  +S TT        
Sbjct: 3634 STTSHSRPGSTHTTAFPDSTTTPGLSR--HSTTSHSSPGSTDTTLLPASTTT------SG 3685

Query: 1141 PSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKE 1200
             S+ ST+         SS+ S D+ +S  S  A +      T   S  S+  T+      
Sbjct: 3686 SSQESTTS-------HSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTT 3738

Query: 1201 KEKVAVSDSESVSLSGSPKS--SPTSASACGAQG-----LRQPGSKY-----------PD 1242
               +  + +   S +GSP++  SP S+++ G QG        P S +           P 
Sbjct: 3739 SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPV 3798

Query: 1243 IASPTFRRLFGAKAGGKSASAPNTEG--VKSSSVMPSPSTTLARQGSLESPSSGTGSMGS 1300
              S T+ R  G+       ++  T G   KS+    SP  +     S  S +SG G   +
Sbjct: 3799 EESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE-ST 3857

Query: 1301 AGGLSGSSSPLFNKPSDLTTDVIS-LSHSLASSP------ASVHSFTSGGLVWAANMSSS 1353
               +S  S+ +   P   TT  +S  S +  SSP       S  S TS G+   +  S S
Sbjct: 3858 TSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 3917

Query: 1354 SAGS-KDTPSYQSMTSLHTSSESIDLPLSHHGSLS------GLTTGT--HEVQSLLMRTG 1404
              GS   T S  S T+   S ES  +  S  GS          TT     E  +   R  
Sbjct: 3918 QPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPA 3977

Query: 1405 SVRSTL-SESMQLDRNTLPKKGLRYTPSSRQANQEEGKEW--LRSHSTGGLQDTGNQSPL 1461
            S  +TL +E       T        +P+S Q           L   ST     +G+    
Sbjct: 3978 STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTK 4037

Query: 1462 VSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPG 1493
            +SP+  ++S        + +SP++     LPG
Sbjct: 4038 LSPARSTTSGLVGESTPSRLSPSSTETTTLPG 4069



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 239/1173 (20%), Positives = 399/1173 (34%), Gaps = 158/1173 (13%)

Query: 209  PSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGAS- 267
            PS +    T+     S  +    +S  S ++ S  + T LPG    P+    S     S 
Sbjct: 4028 PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 4087

Query: 268  -----NLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTA----GQP 318
                  L+  + + + + +    +++      ++  P S++  +G  Q P+T+    G  
Sbjct: 4088 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTT-TSGLSQEPTTSHSSQGST 4146

Query: 319  PASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATS-------PTPSSD------- 364
             A+  P  + +     +S     S   T  T+    T TS       PT SS        
Sbjct: 4147 EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL 4206

Query: 365  -----------------RLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGP 407
                             +  P  S+   + PS     +E     ++R +  P    S+  
Sbjct: 4207 TPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASS 4266

Query: 408  SDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNL-----SNKKSL 462
            +  G+ +++ +         + L    S  S     P  +P  +GS        S   + 
Sbjct: 4267 TTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAG 4326

Query: 463  LQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIP 522
            L  K     +  ++   T  P       V+E +    S+     P    TTA    + +P
Sbjct: 4327 LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR-----PGSMHTTAFPSSTTMP 4381

Query: 523  -----SSSGIPKPGSKVPTVKQTISPGSTASK----ESEKFRTTKGSPSQSLSKPITMEK 573
                 S++    PGS       T+SPGST +     ES  F ++ GS   +L    T   
Sbjct: 4382 GVSQESTASHSSPGS----TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTAS 4437

Query: 574  A--SASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVA 631
                AS+      G      SP+GS T     ++ QS  N     P       P T T A
Sbjct: 4438 GLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPA------PPTTTSA 4491

Query: 632  PFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIAD 691
                   S    ++ P+     S T +  S   T        +   P   R  T    + 
Sbjct: 4492 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT----SG 4547

Query: 692  LRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRL 751
            L +      SS   TQ  H      F  + TT   G       S  T             
Sbjct: 4548 LVEESTTYHSSPGSTQTMH------FPESNTTSGRGEESTTSHSSTTH------------ 4589

Query: 752  QAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDM 811
                APS  +      TS   H+ P     T     +  S      + + S  + S  D 
Sbjct: 4590 TISSAPSTTSALVEEPTS--YHSSPGSTATTHFPDSSTTS-----GRSEESTASHSSQDA 4642

Query: 812  SSEVDVGGYMSDGDILGKSLRTDDINSGYM---------TDGGLNLYTRSLNRIPDT--- 859
            +  + +    +   +LG+S  T  I+SG M         T  GL+  + + +  P +   
Sbjct: 4643 TGTIVLPARSTTSVLLGES-TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPT 4701

Query: 860  ---ATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITV 916
               + S   + R     TV +     +++ S   S T   +  +     SS  S   +  
Sbjct: 4702 THFSASSTTLGRSEESTTVHSSPVATATTPSPARS-TTSGLVEESTAYHSSPGSTQTMHF 4760

Query: 917  PSRKNTQLRTDSEK--RSTTDETWDSPEELKKP--EEDFDSHGDAGGKWKTVSSGLPEDP 972
            P       R++  +   S+T  T  SP        EE    H   G      ++  PE  
Sbjct: 4761 PESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPG---SIATTHFPESS 4817

Query: 973  EKAGQKASLSVSQTGSWRRGMS---AQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPL 1029
              +G+    + S +     G++   A      R    T+   +PG  +   AS    A  
Sbjct: 4818 TTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLAS---TATT 4874

Query: 1030 KGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSG 1089
             G S + +   +   S D+   P S       TSS    +P+ + S A  T + A   + 
Sbjct: 4875 PGLSAKSTILYSSSRSPDQTLSPAS------MTSSSISGEPTSLYSQAESTHTTA-FPAS 4927

Query: 1090 SATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGI 1149
            + T G   +S     K  +   T   GS          ++  +    +L   S +ST+ +
Sbjct: 4928 TTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTT-V 4986

Query: 1150 PGRGGHR----SSTSSIDSNVSSKS-AGATTSKLREPTKIGSGRSS---PVTVNQTDKEK 1201
            PG         SS  S ++   S S   +  S+   P     G +    P T+  TD  +
Sbjct: 4987 PGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQ 5046

Query: 1202 EKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSA 1261
            E  A   S     S +  ++P  A +  +  + +P + Y    SPT+  LF A     S+
Sbjct: 5047 ESTAFHSS-----SDATGTTPLPARSTASDLVGEPTTFYIS-PSPTYTTLFPA----SSS 5096

Query: 1262 SAPNTEGVKSSSVMPSPSTTLARQGSLESPSSG 1294
            ++  TE   +    PS ++T+    SLE+ + G
Sbjct: 5097 TSGLTEESTTFHTSPSFTSTIVSTESLETLAPG 5129



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 232/1124 (20%), Positives = 383/1124 (34%), Gaps = 144/1124 (12%)

Query: 301  SSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPT 360
            SSSG  G    P+ +         +PS   P  +++  +  S T+  L+ K ++  TSP 
Sbjct: 4029 SSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR 4088

Query: 361  PSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSES 420
                 L P       T  SG          V+  ++    QP       G     AF +S
Sbjct: 4089 SPDATLSP-----ATTTSSG----------VSEESSTSHSQP-------GSTHTTAFPDS 4126

Query: 421  GEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCT 480
                G +    +  S+  S + +  L+P    + +L  + +       +     +  +  
Sbjct: 4127 TTTSGLSQEPTTSHSSQGSTEAT--LSPGSTTASSLGQQSTTFHSSPGD----TETTLLP 4180

Query: 481  EKPVKEEKDQVTEMAPKKTSKI-ASLIPKGSKTTAAKKESLI----PSSSG-IPKPGS-- 532
            +  +     + +      T  +  +L P  S +T  ++ES      PSSS   P P S  
Sbjct: 4181 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTT 4240

Query: 533  KVPTVKQTI---SPGSTASKESEKFRTTKGSPSQSL---SKPITMEKA--SASSCPAPLE 584
             VP    T     P ST +       TT G   +S    S P     A     S  + L 
Sbjct: 4241 AVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLV 4300

Query: 585  GREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGT 644
            G        SGS   T    S  + G              P+T T++P    A + + G 
Sbjct: 4301 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT-TLSP----ASTTSSGV 4355

Query: 645  ALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLR 704
            +  S  S + P  M      TA      + G   E+    +     D   +   T +S  
Sbjct: 4356 SEESTTSHSRPGSM----HTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSL 4411

Query: 705  GTQISHSTLETTFDSTVTTEV-NGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGY 763
            G +   +T  ++  ST TT + +  T   L    TP+    G     L    + +     
Sbjct: 4412 GPE--STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT----- 4464

Query: 764  PRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSD 823
             R G S    + P+    TTP      S    +S       +S+            + + 
Sbjct: 4465 -RQGESTTFQSWPNS-KDTTPAPPTTTSAFVELSTTSHGSPSST--------PTTHFSAS 4514

Query: 824  GDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDS 883
               LG+S  +  ++S  +          +    P  +T+  +++      +    +    
Sbjct: 4515 STTLGRSEESTTVHSSPV--------ATATTPSPARSTTSGLVEESTTYHSSPGSTQTMH 4566

Query: 884  SSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEE 943
               S+  S   +  +T   +TT ++SS  + T    +       S   + T    DS   
Sbjct: 4567 FPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTT 4626

Query: 944  LKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQ 1003
              + EE   SH          ++G    P ++     L  S T     G           
Sbjct: 4627 SGRSEESTASHSSQD------ATGTIVLPARSTTSVLLGESTTSPISSG----------- 4669

Query: 1004 KAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDA-----GKSSGDEGKKPPSGIGR 1058
               T+AL  PG T     SE      K ++   SPS         SS   G+   S    
Sbjct: 4670 SMETTAL--PGSTTTPGLSE------KSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVH 4721

Query: 1059 STATSSFGFKKPSGVGSSAMITSSGATITS-GSATLGKIPKSAAIGGKSNAGRKTSLDGS 1117
            S+  ++     P+   +S ++  S A  +S GS      P+S+   G+S   R +    +
Sbjct: 4722 SSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTT 4781

Query: 1118 QNQDDVVLHVSS--KTTLQYRSLPR-------PSKSSTSGIPGRGGHRSSTSSIDSN-VS 1167
                      S+  +    Y S P        P  S+TSG        +S SS D+N ++
Sbjct: 4782 HTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEES--TASHSSPDTNGIT 4839

Query: 1168 SKSAGATTS-KLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSAS 1226
               A  TTS ++ E T       S  T   +      ++   +   S S SP  + + AS
Sbjct: 4840 PLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPAS 4899

Query: 1227 ACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNT-----EGVKSSSVMPSPSTT 1281
               +    +P S Y   A  T    F A       S  +T      G   +++ P   TT
Sbjct: 4900 MTSSSISGEPTSLYSQ-AESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITT 4958

Query: 1282 LARQGSLESPSSGTGSMGS--------AGGLSGSSSPLFNKPSDLTTDVISLSHSLASSP 1333
             +      +P S  GS  S          GLS  S+  ++ P   +T+  + SH   S+ 
Sbjct: 4959 SSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPG--STETTAFSH---SNT 5013

Query: 1334 ASVHSFTSGGLVWAANMSSS--SAGSKDTPSYQSMTSLHTSSES 1375
             S+HS  S     +   + +   A    T   Q  T+ H+SS++
Sbjct: 5014 MSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDA 5057


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 300/1409 (21%), Positives = 515/1409 (36%), Gaps = 184/1409 (13%)

Query: 206  ASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQG 265
            A   +   ++ T     SS   R A  +  S     +   T    PS +P    S++   
Sbjct: 252  AGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFV--EPSTTSHGSPSSIPTTHISAR-ST 308

Query: 266  ASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPS 325
             S L   S +++S   +    +   ++  S +G +S++  +      S+A    ++ +  
Sbjct: 309  TSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE 368

Query: 326  P-----------------SASKPWRSKSMNVKHS---ATSTMLTVKQSSTA-------TS 358
            P                 S++   RS+     HS   AT T++   +S+T+       TS
Sbjct: 369  PTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 428

Query: 359  PTPSSDRLKPPVSEGVKTAPS-GQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAF 417
            P  SS  ++     G  T P   ++S        +  T L P    SSG S+      + 
Sbjct: 429  PI-SSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSR 487

Query: 418  SESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNK 477
              S     F     + G +  S   +   + P +    L    +      +E      + 
Sbjct: 488  PGSTHTTAFPDSTTTPGLSRHS---TTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSS 544

Query: 478  VCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTV 537
              T+  +            + T+  ++    GS  T    +S   +SSGI +  ++V + 
Sbjct: 545  GSTDTALSPGSTTALSFGQESTTFHSN---PGSTHTTLFPDST--TSSGIVEASTRVHSS 599

Query: 538  ----KQTISPGSTASK----ESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAG 589
                + T+SP S+ S     ES  F+T   S   + S P        S+  AP+E     
Sbjct: 600  TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPP--------STATAPVEESTTY 651

Query: 590  QASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSA 649
              SP GS   T   +S  ++G+          HS P+ +   P    AHS   G    S 
Sbjct: 652  HRSP-GSTPTTHFPASSTTSGHSE---KSTIFHSSPDASGTTPS--SAHSTTSGRG-EST 704

Query: 650  DSCTSPTKMDLSY--SKTAKQCLEEISGEDPETRRMRTVKNIADLRQNL---EETMSSLR 704
             S  SP   +++     T    L E S     + R  T         +L   EE+ +S  
Sbjct: 705  TSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 764

Query: 705  GTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYP 764
                +HST+     +T        T+ + +SR +  T     +      G+ P+     P
Sbjct: 765  QPGSTHSTVSPASTTTPGLSEESTTVYS-SSRGSTETTVFPHSTTTSVHGEEPTTFHSRP 823

Query: 765  RSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKAS---SDLDMSSEVDVGGYM 821
             S T   + T+ S    T+ L   + +  G+ +       A+   +DL   S        
Sbjct: 824  AS-THTTLFTEDST---TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG 879

Query: 822  SDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDAD--- 878
            S G  L  +  T     G  T   L+  +     +P + T+  + ++     T       
Sbjct: 880  STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 939

Query: 879  SWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETW 938
            +   +++ SSG+S+  ++ ++     ++  +++ + T  S  + +  T    + +T+ T 
Sbjct: 940  TLSPATTTSSGVSE--ESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATL 997

Query: 939  D--SPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAG--QKASLSVSQTGSWRRGMS 994
               S       ++    H   G    T+   LP+D   +G  + ++ + S TGS    ++
Sbjct: 998  SPGSTTASSLGQQSTTFHSSPGDTETTL---LPDDTITSGLVEASTPTHSSTGSLHTTLT 1054

Query: 995  AQGGAPSRQKAGTSALKTPGKTDDAKASEKGK--APLKGSSLQRSPSDAGKSSGDEGKKP 1052
                  +  +  ++  ++   + D   S  G   AP++ S+   S   +  ++       
Sbjct: 1055 PASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASS- 1113

Query: 1053 PSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATL-----GKIPKSAAIGGKSN 1107
             + +GRS  +++     P   G++   T S  ++  G  T      G    +A  G  + 
Sbjct: 1114 -TTLGRSEESTTV-HSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT 1171

Query: 1108 AG---RKTSLDGSQNQDDVVLHVSSKTTL-----QYRSLPRPSKSSTSGIPGR----GGH 1155
            AG   + T+   S    D  L  +S T+         S  RP  + T+  PG     G  
Sbjct: 1172 AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVS 1231

Query: 1156 RSSTSSIDSNVSSK---SAGATTSKLREP--TKIGSGRSSPVTVNQTDKEKEKVAVSDSE 1210
            + ST+S  S  S+    S G+TT+    P  T   S   S  T    D       +  S 
Sbjct: 1232 QESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEAST 1291

Query: 1211 SV-SLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGV 1269
             V S +GSP ++ + A +   QG            S TF+            S P+    
Sbjct: 1292 PVHSSTGSPHTTLSPAGSTTRQG-----------ESTTFQ------------SWPS---- 1324

Query: 1270 KSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSL 1329
             S   MP+P TT +    L + S G+ S       S SS+ L    S+ +T V S   + 
Sbjct: 1325 -SKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR--SEESTTVHSSPVAT 1381

Query: 1330 ASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY-QSMTSLHTSSES------------- 1375
            A++P+   S TS GLV  +    SS GS  T  + +S T+   S ES             
Sbjct: 1382 ATTPSPARSTTS-GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS 1440

Query: 1376 --------IDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLR 1427
                    ++ P S+H S   + T TH  +S      S  ST S S   D N +      
Sbjct: 1441 PPSTTSALVEEPTSYHSSPGSIAT-THFPESSTTSGRSEESTASHSSP-DTNGITPLPAH 1498

Query: 1428 YTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLV-SPTNL 1486
            +T S R A      E    + + G  +T   S   +P   + S     + S+LV  PT  
Sbjct: 1499 FTTSGRIA------ESTTFYISPGSMETTLASTATTPGLSAKSTI--LYTSDLVGEPTTF 1550

Query: 1487 SQFNLPGPSMMRSNSIPAQDSSFDLYDDS 1515
                   PS   +   PA  S+  L ++S
Sbjct: 1551 ----YISPSPTYTTLFPASSSTSGLTEES 1575



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 307/1472 (20%), Positives = 491/1472 (33%), Gaps = 168/1472 (11%)

Query: 333  RSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVN 392
            RS+     HS+   M T    + +T      D    P+S G     +   S  +      
Sbjct: 63   RSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEK 122

Query: 393  ARTALRPPQPP----------SSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKV 442
            + T    P+ P          SSG S+      +   S     F       G +  S   
Sbjct: 123  STTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTAS 182

Query: 443  SPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKI 502
                 P        S   S L P+     +R  +   T  P       + E +    S  
Sbjct: 183  HSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSST 242

Query: 503  AS----LIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQT-ISPGSTASKESEKFRTT 557
             S    L P GS T   +  +               P+ K T  +P +T S   E   T+
Sbjct: 243  RSPHTTLSPAGSTTRQGESTTF-----------HSWPSSKDTRPAPPTTTSAFVEPSTTS 291

Query: 558  KGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLP 617
             GSPS   S P T   ++ S+    +E      +SP  + TM   +S   ++G G     
Sbjct: 292  HGSPS---SIP-TTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESD-TTSGRGEESTT 346

Query: 618  QQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGED 677
                 +H  T + AP    A  E E T+  S+   T+ T    S + + +   EE +   
Sbjct: 347  SHSSTTH--TISSAPSTTSALVE-EPTSYHSSPGSTATTHFPDSSTTSGRS--EESTASH 401

Query: 678  PETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRP 737
                   T+  +   R      +     + IS  ++ET      T      T P L+ R 
Sbjct: 402  SSQDATGTI--VLPARSTTSVLLGESTTSPISSGSMET------TALPGSTTTPGLSERS 453

Query: 738  TPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSR-----FIHTDPSRFMYTTP--LRRAAV 790
            T  T+      P      A +  +G     T+        HT       TTP   R +  
Sbjct: 454  T--TFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTT 511

Query: 791  SRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDG--DILGKSLRTDDINSGY-MTDGGLN 847
            S     S       AS+     S+     + S G  D       T  ++ G   T    N
Sbjct: 512  SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSN 571

Query: 848  LYTRSLNRIPDTATSRDIIQRG--VHDVT-VDADSWDDSSSVSSGLSDTLDNISTDDLNT 904
              +      PD+ TS  I++    VH  T     +   +SS S GL        T   +T
Sbjct: 572  PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 631

Query: 905  TSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEED-FDSHGDAGGKWKT 963
             ++ S  S  T P  ++T          TT     S       +   F S  DA G   T
Sbjct: 632  HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG---T 688

Query: 964  VSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTP---------- 1013
              S         G+  +  +S   +    +      P   +A T+   +P          
Sbjct: 689  TPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPA 748

Query: 1014 -------GKTDDAKASEKGK-----APLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTA 1061
                   G+      S+ G      +P   ++   S       S   G    +    ST 
Sbjct: 749  SMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTT 808

Query: 1062 TSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGS---- 1117
            TS  G ++P+   S    T +    T  S T G   +S A  G S A  +T L  +    
Sbjct: 809  TSVHG-EEPTTFHSRPASTHT-TLFTEDSTTSGLTEESTAFPG-SPASTQTGLPATLTTA 865

Query: 1118 -QNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRG-GHRSSTSSIDSNVSSKSAGATT 1175
               ++      SS +T    S   P++S+TSG+ G     R S SS ++     S    +
Sbjct: 866  DLGEESTTFPSSSGSTGTKLS---PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS 922

Query: 1176 SKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQ 1235
               +  T   S RS   T++        V+   S S S  GS  ++    S   +   ++
Sbjct: 923  LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQE 982

Query: 1236 PGSKYPDIASPTFRRLFG----AKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESP 1291
            P + +    S       G    +  G +S +  ++ G   ++++P  + T     +    
Sbjct: 983  PTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 1042

Query: 1292 SSGTGSM--------GSAGGLSGSSSPLFNKPSDLTT------------DVISLSHSLAS 1331
             S TGS+         ++ GL   S+   + PS   T            +V +  HS  S
Sbjct: 1043 HSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPS 1102

Query: 1332 SPASVH---SFTSGGLVWAANMSSSSAGSKDTPSY--QSMTSL-----------HTSSES 1375
            S  + H   S T+ G    +    SS G+  T  +  +S TS+             S+E+
Sbjct: 1103 STPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTET 1162

Query: 1376 IDLPLS-HHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTL-PKKGLRYTPSSR 1433
              LP S     LS  +T  +        T S  ST S  +  +  T   + G  +T +  
Sbjct: 1163 TALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 1222

Query: 1434 QANQEEG--KEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAG----KYHFSNLVSPTNLS 1487
             +    G  +E   SHS+ G  DT      +SP + ++S+ G     +H S   + T L 
Sbjct: 1223 GSTTMPGVSQESTASHSSPGSTDT-----TLSPGSTTASSLGPESTTFHSSPGSTETTLL 1277

Query: 1488 QFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSAT-------------SLEERPRAISHS 1534
              N     ++ + S P   S+   +      GS T             S +  P   + +
Sbjct: 1278 PDNTTASGLLEA-STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTT 1336

Query: 1535 GSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLTSQLSA 1594
             +F +     HGS  S  ++  S  ST      SE+   +    VA+    +   S  S 
Sbjct: 1337 SAFVELSTTSHGSPSSTPTTHFSASSTT--LGRSEESTTVHSSPVATATTPSPARSTTSG 1394

Query: 1595 NAHLVAAFEKSLGN-MTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALN 1653
                  A+  S G+  T      +  + + E        T   + +  S   A ++   +
Sbjct: 1395 LVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTS 1454

Query: 1654 GPDHPPKDLRIR-RQHSSESVSSINSATSHSS 1684
                P         + S+ S  S  S  SHSS
Sbjct: 1455 YHSSPGSIATTHFPESSTTSGRSEESTASHSS 1486



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 243/1176 (20%), Positives = 402/1176 (34%), Gaps = 118/1176 (10%)

Query: 200  QQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQK---KPTRLPGPSRVPA 256
            ++  T  S P             +   +R++T S+ S  +T        T   GPS+   
Sbjct: 479  EESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST 538

Query: 257  AGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQS--SSG-VNGNVQPPS 313
               SS     + L+  S +  S  +     ++N     ++  P S  SSG V  + +  S
Sbjct: 539  TSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHS 598

Query: 314  TAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRL-KPPVSE 372
            + G P  +  P+ S S   + +S   +    ST  T    STAT+P   S    + P S 
Sbjct: 599  STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 658

Query: 373  GVKTAPSGQKSM--LEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFS-------ESGEM 423
                 P+   +    EK  + ++        P S+  +  G+ +   S       E   +
Sbjct: 659  PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTL 718

Query: 424  EGFNS--GLNSGGSTNSSPKVSPKLAPPKAGSKNLS-NKKSLLQPKEKEEKNRDKNKVCT 480
             G  +  GL+   +T  S   SP      A   +L   ++S     +    +   +   T
Sbjct: 719  PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAST 778

Query: 481  EKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQT 540
              P   E +  T  +  + S   ++ P  + T+   +E     S    +P S   T+   
Sbjct: 779  TTPGLSE-ESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHS----RPASTHTTL--- 830

Query: 541  ISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQAS---PSGSC 597
             +  ST S  +E+     GSP+           ++ +  PA L   + G+ S   PS S 
Sbjct: 831  FTEDSTTSGLTEESTAFPGSPA-----------STQTGLPATLTTADLGEESTTFPSSSG 879

Query: 598  TMTVAQSSGQSTGNGAV--QLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSP 655
            +     S  +ST +G V    P +   S   T T+              +  S    TSP
Sbjct: 880  STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLP-----GSPTTPSLSEKSTTFYTSP 934

Query: 656  TKMDLSYS---KTAKQCLEEISGEDPETRRMRTV-----KNIADLRQNLEETMSSLRGTQ 707
               D + S    T+    EE S    +     T         +DL Q    + SS   T+
Sbjct: 935  RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTE 994

Query: 708  ISHSTLETTFDSTVTTEVNGRTIPNLTSR----PTPMTWRLGQACPRLQAGDAPSLGAGY 763
             + S   TT  S         + P  T         +T  L +A     +          
Sbjct: 995  ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 1054

Query: 764  PRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSD 823
            P S TS  +  + + F           S  G  +     E +++     S      + + 
Sbjct: 1055 PASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAA--PVEVSTTYHSRPSSTPTTHFSAS 1112

Query: 824  GDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDS 883
               LG+S  +  ++S     G     TRS   +     +   I  G  + T         
Sbjct: 1113 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTA-----LPG 1167

Query: 884  SSVSSGLSD--TLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSP 941
            S+ ++GLS+  T    S    +TT S +S ++  V     T     S  R  +  T   P
Sbjct: 1168 STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTT-----SHSRPGSTHTTAFP 1222

Query: 942  EELKKP---EEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG 998
                 P   +E   SH   G    T+S G        G +++   S  GS    +     
Sbjct: 1223 GSTTMPGVSQESTASHSSPGSTDTTLSPG-STTASSLGPESTTFHSSPGSTETTLLPDNT 1281

Query: 999  APSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGR 1058
              S     ++ + +   +     S  G    +G S   +   +  SS D    PP     
Sbjct: 1282 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGES---TTFQSWPSSKDTMPAPP----- 1333

Query: 1059 STATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQ 1118
             T TS+F     +  GS +  ++     ++ S TLG+  +S  +     A   T      
Sbjct: 1334 -TTTSAFVELSTTSHGSPS--STPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARS 1390

Query: 1119 NQDDVV----LHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGAT 1174
                +V     + SS  + Q    P  S +S      R  H S+T +I S  S+     T
Sbjct: 1391 TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST-----T 1445

Query: 1175 TSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLR 1234
            ++ + EPT   S  SSP ++  T            ES + SG  + S  S S+    G+ 
Sbjct: 1446 SALVEEPT---SYHSSPGSIATT---------HFPESSTTSGRSEESTASHSSPDTNGIT 1493

Query: 1235 QPGSKYPD---IASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESP 1291
               + +     IA  T   +         AS   T G+ + S +   S  +    +    
Sbjct: 1494 PLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTFYIS 1553

Query: 1292 SSGT-----GSMGSAGGLSGSSSPLFNKPSDLTTDV 1322
             S T      +  S  GL+  S+     PS  +T V
Sbjct: 1554 PSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIV 1589



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 306/1501 (20%), Positives = 504/1501 (33%), Gaps = 244/1501 (16%)

Query: 200  QQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGS 259
            + + +H+SP + A+         S L       S  S I++   + T LPG +  P    
Sbjct: 66   ESKASHSSPDAMATTVLPAGSTPSVLVG----DSTPSPISSGSMETTALPGSTTKPG--- 118

Query: 260  SSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQS--SSGVNGNVQPPSTAGQ 317
                     L+ +S +F          Y++    D++  P S  SSGV            
Sbjct: 119  ---------LSEKSTTF----------YSSPRSPDTTHLPASMTSSGV------------ 147

Query: 318  PPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTA 377
               S   + S S+P  + +     S T   L+ + +++ +SP P+   L P    G  TA
Sbjct: 148  ---SEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSP----GSTTA 200

Query: 378  PS-GQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGE--MEGFNSGLNSGG 434
             S G +      +  +  T L P    +SG  +      + + S    +    S    G 
Sbjct: 201  SSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGE 260

Query: 435  STN-----SSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKD 489
            ST      SS    P  APP   S  +    +               +  T   V+E   
Sbjct: 261  STTFHSWPSSKDTRP--APPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTT 318

Query: 490  QVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTI-------- 541
              +     +T          S TT+ + E    S S      S  P+    +        
Sbjct: 319  YHSSPGSTQTMHFPE-----SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYH 373

Query: 542  -SPGSTASKESEKFRTTKGSPSQSLSKPITMEKAS-----ASSCPAPLEGREAGQASPSG 595
             SPGSTA+       TT G   +S +   + +        A S  + L G        SG
Sbjct: 374  SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSG 433

Query: 596  SCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEG------------ 643
            S   T    S  + G     L ++    H +  + A  +  A + + G            
Sbjct: 434  SMETTALPGSTTTPG-----LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRP 488

Query: 644  -----TALPSADSCTSP------TKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADL 692
                 TA P  DS T+P      T    S   T    L   +     ++   T  + +  
Sbjct: 489  GSTHTTAFP--DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSG- 545

Query: 693  RQNLEETMSSLRGTQISHSTLETTFDST-----VTTEVNGRTIPNLTSRPTPMTWRLGQA 747
              + +  +S    T +S     TTF S       T   +  T   +    T +    G  
Sbjct: 546  --STDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS- 602

Query: 748  CPRLQAGDAPSLGAGYPRSGTS-----RFIHTDPS-RFMYTTPLRRAAVSRLGNMSQIDM 801
             PR     A S   G     T+        HT PS     T P+  +        S    
Sbjct: 603  -PRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 661

Query: 802  SEKASSDLDMSSEVDVGGYMSDGDILG---KSLRTDDINSGYMTDGGLNLYTRSLNRIPD 858
               ASS     SE     + S  D  G    S  +     G  T   ++  +  +  +P 
Sbjct: 662  HFPASSTTSGHSEKST-IFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 720

Query: 859  TATSRDIIQRGV---HDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNIT 915
            + T+  + +              +   +S  S G+ +     S     +T S  S ++ T
Sbjct: 721  STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE-STTSRSQPGSTHSTVSPASTT 779

Query: 916  VPSRKNTQLRTDSEKRSTTDETW--DSPEELKKPEEDFDSHGDAGGKWKTV------SSG 967
             P          S  R +T+ T    S       EE    H        T+      +SG
Sbjct: 780  TPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSG 839

Query: 968  LPED---------PEKAGQKASLSVSQTGSWRRGMSAQGGAP----SRQKAGTSALKTPG 1014
            L E+           + G  A+L+ +  G       +  G+     S  ++ TS L    
Sbjct: 840  LTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGES 899

Query: 1015 KTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVG 1074
                   S      L GS    S S+   +     + P + +  +T TSS G  + S   
Sbjct: 900  TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS-GVSEESST- 957

Query: 1075 SSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLD------GSQNQDDVVLHVS 1128
            S +   S+  T    S T   + +       S    + +L        S  Q     H S
Sbjct: 958  SHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSS 1017

Query: 1129 ---SKTTLQYRSLPRPSKSSTSG-IPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKI 1184
               ++TTL       P  + TSG +       SST S+ + ++   A +T++ L+E +  
Sbjct: 1018 PGDTETTL------LPDDTITSGLVEASTPTHSSTGSLHTTLT--PASSTSAGLQEEST- 1068

Query: 1185 GSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIA 1244
             + +S P + + T       A     S +    P S+PT+  +  +  L +        +
Sbjct: 1069 -TFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHS 1127

Query: 1245 SP--TFRRLFGAKAG-----GKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGS 1297
            SP  T   LF  ++      G+  ++P + G   ++ +P  +TT                
Sbjct: 1128 SPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT---------------- 1171

Query: 1298 MGSAGGLSGSSSPLFNKP----------SDLTTDVISLSHSLASSPASVH------SFTS 1341
                 GLS  S+  ++ P          S  ++ V   S +  S P S H      S T 
Sbjct: 1172 ----AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTM 1227

Query: 1342 GGLVWAANMSSSSAGSKDT---PSYQSMTSL-------HTSSESIDLP-LSHHGSLSGLT 1390
             G+   +  S SS GS DT   P   + +SL       H+S  S +   L  + + SGL 
Sbjct: 1228 PGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLL 1287

Query: 1391 TGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTG 1450
              +  V S    TGS  +TLS +    R        +  PSS+            + +  
Sbjct: 1288 EASTPVHS---STGSPHTTLSPAGSTTRQG-ESTTFQSWPSSKDTMPAPP---TTTSAFV 1340

Query: 1451 GLQDTGNQSPLVSPS---AMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDS 1507
             L  T + SP  +P+   + SS+  G+   S  V  + ++    P P+   ++ +  + +
Sbjct: 1341 ELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEEST 1400

Query: 1508 SFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAH 1567
            ++     S      T     P + + SG   +S    H S+   +SS  S  S   E+  
Sbjct: 1401 AYHSSPGS------TQTMHFPESSTASGRSEESRTS-HSSTTHTISSPPSTTSALVEEPT 1453

Query: 1568 S 1568
            S
Sbjct: 1454 S 1454


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 92.0 bits (227), Expect = 6e-18
 Identities = 287/1405 (20%), Positives = 508/1405 (36%), Gaps = 187/1405 (13%)

Query: 245  PTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSG 304
            PT  PG    P            +   R+ S   +D + P   +     +++  P ++ G
Sbjct: 915  PTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTST----EATSSPTTAEG 970

Query: 305  VNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSD 364
             +     PS    P  S   S +      + +++     ++T LT   S+ A+SP P+++
Sbjct: 971  TSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTT--STEASSPPPTAE 1028

Query: 365  RLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEME 424
                P S      PS   + L +  +     A       S+ P+D       +S++    
Sbjct: 1029 GTSMPTS-----TPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSS 1083

Query: 425  GFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPK----------EKEEKNRD 474
                G +   ST S    +P  + P +    +S++ S L               E  +  
Sbjct: 1084 TTADGTSMPTSTYSEGS-TPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSP 1142

Query: 475  KNKVCTEKPVKEEKDQVTEMA--PKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGS 532
                 T  P     +  T +A  P  T+ + S       TT    ++ + +S+    P  
Sbjct: 1143 TTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPP- 1201

Query: 533  KVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQAS 592
              PT + T  P ST  +     R+T  +       P+   +AS  S  +P++       S
Sbjct: 1202 --PTAEVTSMPTSTPGE-----RSTPLTSMPVRHTPVASSEASTLST-SPVDTSTPVTTS 1253

Query: 593  PSGSCTMTVAQSSG---QSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSA 649
               S + T A+ +     +T  G+  L      +   T+  A  +     + +G  + S 
Sbjct: 1254 AETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSN 1313

Query: 650  DSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQIS 709
            +  +SPT  + +   T+        G  P T        +A         +S L  T + 
Sbjct: 1314 EVSSSPTPAEGTSMPTSTYS----EGRTPLTSIPVNTTLVAS------SAISILSTTPVD 1363

Query: 710  HSTLETTFDSTVT--TEVNGRTIPN---------LTSRPTPMTWRLGQACPRLQA----- 753
            +ST  TT     +  T   G ++PN         LTS P   T  +      L A     
Sbjct: 1364 NSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDT 1423

Query: 754  ---GDAPSLGAGYPRSGTSRFIHTD-PSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDL 809
               G   +     P +     I T  PS     TPL+   VS    ++  + S  +++ +
Sbjct: 1424 STPGTTSAEATSSPTTAEGISIPTSTPSEGK--TPLKSIPVSNTP-VANSEASTLSTTPV 1480

Query: 810  DMSSEVDVGGYMSDGDILGK----SLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDI 865
            D +S V     +S      +    ++ T    S  +T   ++  T + + I   +T+  +
Sbjct: 1481 DSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAV 1540

Query: 866  IQRGVHDVTVDADS---WDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNI--TVPSRK 920
                V   +  + S    D +S  +S  S+    +++  ++T   VSS +N   T P   
Sbjct: 1541 TSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDS 1600

Query: 921  NTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKAS 980
             TQ+   +E  S+T     S   +  P E         G     S  +   P  + + ++
Sbjct: 1601 KTQVTASTEASSSTTAEGSSMT-ISTPSE---------GSPLLTSIPVSTTPVASPEAST 1650

Query: 981  LSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASE--KGKAPLKGSSLQRSP 1038
            LS +   S          +P       S+  TP +      S   +G+ PL   +++ +P
Sbjct: 1651 LSTTPVDS---------NSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTP 1701

Query: 1039 SDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPK 1098
                 S+       P        TS+     P+    ++M  S   T + G+  L  IP 
Sbjct: 1702 --VASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNS---TPSEGTTPLTSIPV 1756

Query: 1099 SAA--IGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKS-----------S 1145
            S    +  +++    T +D S          SS TT +  S+P  + S           S
Sbjct: 1757 STTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVS 1816

Query: 1146 TSGIPGRGGHRSSTSSIDSN--VSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEK 1203
             + +        ST+ +DSN  V + +A +++    E T I +   S  +   T      
Sbjct: 1817 HTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVST 1876

Query: 1204 VAVSDSESVSLSGSPKSSPT--------SASACGAQGLRQPGSKYPDIASPTFRRLFGAK 1255
              V+ SE+ +LS +P  + T        S+S   A G   P S   +   P         
Sbjct: 1877 TTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPL-------- 1928

Query: 1256 AGGKSASAPNTEGVKSSSVMPSPSTTLAR--------QGSLESPSSGTGSMGSAGGLSGS 1307
                  S P +    +SS + + STTLA           +  SP++  G+       S  
Sbjct: 1929 -----TSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEG 1983

Query: 1308 SSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMT 1367
            S+PL + P   T  V S + +L+++P           V  +  +++S     +P+    T
Sbjct: 1984 STPLTSMPLSTTLVVSSEASTLSTTP-----------VDTSTPATTSTEGSSSPTTAGGT 2032

Query: 1368 SLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLR 1427
            S+ TS+     P      L+G+   T  V S      S  +TLS +  +D  T   +   
Sbjct: 2033 SIQTST-----PSERTTPLAGMPVSTTLVVS------SEGNTLS-TTPVDSKT---QVTN 2077

Query: 1428 YTPSSRQANQEEGKEWLRSHSTGGLQDTG---NQSPLVSPSAMSSSAAGKYHFSNLVSPT 1484
             T +S  A  E     + + S G    T    + +P+ SP A + S       S +++ T
Sbjct: 2078 STEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITST 2137

Query: 1485 NLSQFNLP--GPSMM------RSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGS 1536
             +S   +P  G SM       R   + +   S  +   S +   +T+  +    +++S  
Sbjct: 2138 EVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTE 2197

Query: 1537 FRDSMEEVHGSSLSLVSSTSSLYST 1561
             R S     G+S+   +ST S  ST
Sbjct: 2198 ARSSPTTSEGTSMP--TSTPSEGST 2220



 Score = 85.1 bits (209), Expect = 7e-16
 Identities = 283/1295 (21%), Positives = 462/1295 (35%), Gaps = 184/1295 (14%)

Query: 418  SESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNK 477
            S + EM    S + S     SS +++P     +  S++ S+  +L  P   E+ +     
Sbjct: 86   STNPEMTSIESSVTSDTPGVSSTRMTP--TESRTTSESTSDSTTLF-PSSTEDTSSPTTP 142

Query: 478  VCTEKPVK--EEKDQVTEMAPKKTSKIASLIPKGSKT------------TAAKKESLIPS 523
              T+ P+    E+   + MA   T+ + S     S T            T A      P 
Sbjct: 143  EGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPE 202

Query: 524  SSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPL 583
            S+ IPK  +   +   T  P ST    S +  T   +P + +S P+T+  A ASS P   
Sbjct: 203  STTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVE-ISTPVTI-SAQASSSPTTA 260

Query: 584  EGREAGQASPSGSCT-----------MTVAQSSGQSTGNGAVQLP---QQQQHSHPNTAT 629
            EG     ++PSG  T           +  +++S  ST   A  +P     +  S P TA 
Sbjct: 261  EGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTA- 319

Query: 630  VAPFIYRAHSENEGTALPSA---DSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTV 686
                        EGT++P++   +  T  T    S    A   +  +S    +T  + T 
Sbjct: 320  ------------EGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTT 367

Query: 687  KNIADLRQNLEETMSSLRGTQISHSTLETTF--DSTVTTEVNGRTIPNLTSRPTPMTWRL 744
                       E  S L  T    ST  T     + +       T   +           
Sbjct: 368  STEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTA 427

Query: 745  GQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEK 804
             +A       +  S+    P  G++       S    TTP+  +  S L + + +D   +
Sbjct: 428  SEASSSPTTAEDTSIATSTPSEGSTPLTSMPVS----TTPVASSEASNL-STTPVDSKTQ 482

Query: 805  ASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINS---GYMTDGGLNLYTRSLNRIPDTAT 861
             ++  + SS                S  T ++NS      ++G   L + S++ +P  ++
Sbjct: 483  VTTSTEASS----------------SPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASS 526

Query: 862  SRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKN 921
                +        VD  +   +SS +S  S T +  S      +   +  +N+ V    +
Sbjct: 527  EASTLS----TTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPV----S 578

Query: 922  TQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASL 981
            T+L   SE  +T+    DS   +    E   S   A G     S+      E+     S+
Sbjct: 579  TRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTST----YSERGTTITSM 634

Query: 982  SVSQTGSWRRGMSAQGGAP--------SRQKAGTSALKTPGKTDDAKASEKGKAPLKGSS 1033
            SVS T       S     P        +  +A +S+    G +       +G  PL  +S
Sbjct: 635  SVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPL--TS 692

Query: 1034 LQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATL 1093
            +  + +    S        P        TS+     P+    ++M TS   T + GS  L
Sbjct: 693  MPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTS---TPSEGSTPL 749

Query: 1094 GKIPKSAAIGGKSNAG--RKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKS------- 1144
              +P S  +   S A     T LD S +         S TT +  S+P  + S       
Sbjct: 750  TSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLT 809

Query: 1145 ----STSGIPGRGGHRSSTSSIDSN--------VSSKSAGATTSKLREPTKIGSGRSSPV 1192
                S + +        ST+ +DSN        VSS    A  + +  PT   S   +P+
Sbjct: 810  SIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSM--PTSTYSEGRTPL 867

Query: 1193 T---VNQTDKEKEKVA------VSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDI 1243
            T   V+ T      ++      V  S  V+ S   +SSPT+     ++G   P S   + 
Sbjct: 868  TSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTT-----SEGTSMPTSTPGEG 922

Query: 1244 ASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGG 1303
            ++P             ++   +T  V SS      +T +     + + +  T S  +A G
Sbjct: 923  STPL------------TSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEG 970

Query: 1304 LSGSSSPLFNKPSDLTTDVIS--LSHSL-ASSPASVHSFTSGGLVWAANMSSSSAGSKDT 1360
             S  +S     PS+ TT + S  +SH+L A+S AS  S T    V +    ++S  +   
Sbjct: 971  TSIPTS----TPSEGTTPLTSTPVSHTLVANSEASTLSTTP---VDSNTPLTTSTEASSP 1023

Query: 1361 PSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNT 1420
            P     TS+ TS+ S            G T  T    S  M   S  STLS +   D +T
Sbjct: 1024 PPTAEGTSMPTSTPS-----------EGSTPLTRMPVSTTMVASSETSTLS-TTPADTST 1071

Query: 1421 LPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNL 1480
                   Y+ +S  +   +G     S  + G   T   S  VS   + SS A     + +
Sbjct: 1072 ---PVTTYSQASSSSTTADGTSMPTSTYSEG--STPLTSVPVSTRLVVSSEASTLSTTPV 1126

Query: 1481 VS--PTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFR 1538
             +  P   S      P+     SIP    S      + +  S T+L     A + S +  
Sbjct: 1127 DTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVS-TTLVVSSEANTLSTTPV 1185

Query: 1539 DSMEEVHGSSLS-----LVSSTSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLTSQLS 1593
            DS  +V  S+ +         TS   ST  E++       +R   VAS E     TS + 
Sbjct: 1186 DSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVD 1245

Query: 1594 ANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELI 1628
             +  +  + E S    T    SL  +   + S L+
Sbjct: 1246 TSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLL 1280



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 243/1213 (20%), Positives = 421/1213 (34%), Gaps = 142/1213 (11%)

Query: 211  EASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLN 270
            E S   T     S+    Y+   +    A     PT        P            +  
Sbjct: 2354 ETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSE 2413

Query: 271  RRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSPSASK 330
              + S   +D + P   +     ++S  P ++ G +    PPS    P AS   S +   
Sbjct: 2414 ASTHSTTPVDTSTPVTTST----EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVV 2469

Query: 331  PWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKL 390
               + +++     TST +T   +  ++SPT + D + P     + TA  G  ++L    +
Sbjct: 2470 SSEAGTLSTTPVDTSTPMTT-STEASSSPTTAEDIVVP-----ISTASEG-STLLTSIPV 2522

Query: 391  VNARTALRPPQPPSSGPSDGGK------DDDAFSESGEMEGFNSGLNSGGST--NSSPKV 442
                 A       S+ P D         +  + + S E     +   S GST   S P  
Sbjct: 2523 STTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVS 2582

Query: 443  SPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKI 502
            +  LA  +A + + +   + +      E +   +   T K         +E++   TS +
Sbjct: 2583 TKPLASSEASTLSTTPVDTSIPVTTSTETS---SSPTTAKDTSMPISTPSEVSTSLTSIL 2639

Query: 503  ASLIPKGS------KTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRT 556
             S +P  S       TT     +L+ +S+G               S   T ++ S    +
Sbjct: 2640 VSTMPVASSEASTLSTTPVDTRTLVTTSTG--------------TSSSPTTAEGSSMPTS 2685

Query: 557  TKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNG-AVQ 615
            T G  S  L+  +      A+S  + L       ++P    T +   SS  +T  G +++
Sbjct: 2686 TPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTP---VTTSAEASSSPTTAEGTSMR 2742

Query: 616  LPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISG 675
            +      S P T+ +   +  A SE          S  S T +D S   T        + 
Sbjct: 2743 ISTPSDGSTPLTSILVSTLPVASSE---------ASTVSTTAVDTSIPVTT----STEAS 2789

Query: 676  EDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTS 735
              P T  + ++        +   T   +  T ++ S   T   + V T     T    +S
Sbjct: 2790 SSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASS 2849

Query: 736  RPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRA--AVSRL 793
             PT      G   P   A +  +L    P S T   + +  +  + TTP+  +    +  
Sbjct: 2850 SPTTAE---GIVVPISTASEGSTLLTSIPVSTTP--VASSEASTLSTTPVDTSIPVTTST 2904

Query: 794  GNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSL 853
               S    +E  S  +   SEV              S     I    +   G    T S 
Sbjct: 2905 EGSSSPTTAEGTSMPISTPSEV--------------STPLTSILVSTVPVAGSEASTLST 2950

Query: 854  NRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSN 913
              + DT T            T  A+      S        L ++S   +   SS +S  +
Sbjct: 2951 TPV-DTRTPVTTSAEASSSPTT-AEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLS 3008

Query: 914  ITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPE 973
             T P+  +T + T +E  S+      +   +  P E         G     S  +   P 
Sbjct: 3009 RT-PADTSTPVTTSTEASSSPTTAEGTGIPISTPSE---------GSTPLTSIPVSTTPV 3058

Query: 974  KAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTP--GKTDDAKASEKGKAPLKG 1031
               + ++LS +   S          +P       S+  TP  G +       +G  PL G
Sbjct: 3059 AIPEASTLSTTPVDS---------NSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTG 3109

Query: 1032 SSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSA 1091
              +  +P     S+       P        TS+     P+    ++M TS   T + GS 
Sbjct: 3110 VPVSTTP--VTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTS---TPSEGST 3164

Query: 1092 TLGKIPKSA--AIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLP--RPSKSST- 1146
             L  +P S    +  + +    T +D S          +S TT +  S+P   PS+  T 
Sbjct: 3165 PLTYMPVSTMLVVSSEDSTLSATPVDTS-TPVTTSTEATSSTTAEGTSIPTSTPSEGMTP 3223

Query: 1147 ------SGIPGRGGHRS--STSSIDSN--VSSKSAGATTSKLREPTKIGSGRSSPVTVNQ 1196
                  S  P      S  ST+ +DSN  +++ +  +++    E T + +   S  +   
Sbjct: 3224 LTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPL 3283

Query: 1197 TDKEKEKVAVSDSESVSLSGSPKSSPT--------SASACGAQGLRQPGSKYPDIASPTF 1248
            T        V+ SE+ +LS +P  + T        S+S   A G   P S Y + ++P  
Sbjct: 3284 TSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLT 3343

Query: 1249 RRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSS 1308
               F       S ++     + ++ V  S   T + + SL SP++  G+       S  +
Sbjct: 3344 NMSFSTTPVVSSEAST----LSTTPVDTSTPVTTSTEASL-SPTTAEGTSIPTSSPSEGT 3398

Query: 1309 SPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTS 1368
            +PL + P   T  V S  ++L+++P       S  LV  +  +SSS    +  S  + T+
Sbjct: 3399 TPLASMPVSTTPVVSSEVNTLSTTPVD-----SNTLVTTSTEASSSPTIAEGTSLPTSTT 3453

Query: 1369 LHTSSESIDLPLS 1381
               S+    +PLS
Sbjct: 3454 SEGSTPLSIMPLS 3466



 Score = 78.2 bits (191), Expect = 9e-14
 Identities = 295/1359 (21%), Positives = 489/1359 (35%), Gaps = 184/1359 (13%)

Query: 223  SSLAARYATQSNHSGIATSQKKPTRLP----GPSRVPAAGSSSKVQGASNLNRRSQSFNS 278
            +S A+   T +  + IATS       P      S  P A S +     + ++ ++Q   S
Sbjct: 427  ASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTS 486

Query: 279  IDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMN 338
             + +  P  A  N   +S   + S+ +       S +  P AS+  S  ++ P       
Sbjct: 487  TEASSSPPTAEVNSMPTSTPSEGSTPLTSM----SVSTMPVASSEASTLSTTP------- 535

Query: 339  VKHSATSTMLTVKQSSTATSPTPSSDRLKPPV-SEGVKTAPSGQKSMLEKFKLVNARTAL 397
                 TST +T    ++++S TP    +     SEG     +   +M    +LV +  A 
Sbjct: 536  ---VDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEG----STPLTNMPVSTRLVVSSEAS 588

Query: 398  RPPQPPSSGPSDGGKDDDAFSESGEMEGFN---SGLNSGGSTNSSPKVSPKLAPPKAGSK 454
                 P+   +      +A S S   EG +   S  +  G+T +S  VS  L      S 
Sbjct: 589  TTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEAST 648

Query: 455  NLSNKKSLLQP--KEKEEKNRDKNKVCTEKPVKEEKDQVTEMA--PKKTSKIASLIPKGS 510
              +       P     E  +       T  P     +  T +   P  T+ +AS      
Sbjct: 649  LSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTL 708

Query: 511  KTTAAKKESLI-----PSSSGIPKPGSKVPTVKQTISPGST--ASKESEKFRTTKGSPSQ 563
             TT     + +      SSS     G+ +PT   T S GST   S    K   T    S 
Sbjct: 709  STTPVDTSTPVTTSTEASSSPTTADGASMPT--STPSEGSTPLTSMPVSKTLLTSSEAST 766

Query: 564  SLSKPITME-----KASASSCPAPLEGREAGQASPS-GSCTMT-VAQSSGQSTGNGAVQL 616
              + P+           AS  P   EG     ++PS GS  +T +  S    T   A  L
Sbjct: 767  LSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTL 826

Query: 617  PQQQQHSHPNTATVAPFIYRAHSENEGTALPS---ADSCTSPTKMDLSYSKTAKQCLEEI 673
                  S+ +  T +  +  + +  EGT++P+   ++  T  T M +S +  A   +  +
Sbjct: 827  STTPVDSN-SPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTL 885

Query: 674  SGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNL 733
            S    +T    T    A       E  S    T    ST  T+   + TT V       L
Sbjct: 886  STTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDS-TTPVVSSEARTL 944

Query: 734  TSRP----TPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAA 789
            ++ P    TP+T    +A       +  S+    P  GT+    T  S     T +  + 
Sbjct: 945  SATPVDTSTPVTTST-EATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSH----TLVANSE 999

Query: 790  VSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLY 849
             S L + + +D +   ++  + SS              G S+ T   + G          
Sbjct: 1000 ASTL-STTPVDSNTPLTTSTEASSPPPTAE--------GTSMPTSTPSEG---------- 1040

Query: 850  TRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVS 909
            +  L R+P + T    +       T+     D S+ V++    +  + + D   T+   S
Sbjct: 1041 STPLTRMPVSTT----MVASSETSTLSTTPADTSTPVTTYSQASSSSTTAD--GTSMPTS 1094

Query: 910  SYSNITVPSRK---NTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSS 966
            +YS  + P      +T+L   SE  + +    D+   +    E   S   A G      +
Sbjct: 1095 TYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEG------T 1148

Query: 967  GLPEDPEKAGQK--ASLSVSQT----------------GSWRRGMSAQGGAPSRQKAGTS 1008
             +P  P   G    AS+ VS T                   +   S +  +P      TS
Sbjct: 1149 SIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTS 1208

Query: 1009 -ALKTPGKTDDAKASEKGK----APLKGSSLQRSPSDAG---KSSGDEGKKPPSGIGRS- 1059
                TPG+      S   +    A  + S+L  SP D      +S +    P +  G S 
Sbjct: 1209 MPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSL 1268

Query: 1060 -TATSSFGFKKPSGVG-SSAMITSSGAT--ITSGSATLGKIPKSAAIGGKSNAGRKTSLD 1115
             T+T+S G    + +  S+ ++TS  A+  +T+   T G +  S  +         TS+ 
Sbjct: 1269 PTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMP 1328

Query: 1116 GSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSN--VSSKSAGA 1173
             S        +   +T L   S+P     +T+ +        ST+ +D++  V++ +   
Sbjct: 1329 TS-------TYSEGRTPL--TSIP----VNTTLVASSAISILSTTPVDNSTPVTTSTEAC 1375

Query: 1174 TTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSP--------KSSPTSA 1225
            ++    E T + +   S  T   T        V  SE+ +LS +P         S+  ++
Sbjct: 1376 SSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATS 1435

Query: 1226 SACGAQGLRQPGSKYPDIASPTFR-RLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLAR 1284
            S   A+G+  P S   +  +P     +         AS  +T  V S+    SP  T   
Sbjct: 1436 SPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSN----SPVVTSTA 1491

Query: 1285 QGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGL 1344
              S  +P+ GT    S    S  S+ L + P   TT   S  +SL+++PA      +   
Sbjct: 1492 VSSSPTPAEGTSIAISTP--SEGSTALTSIPVSTTTVASSEINSLSTTPA-----VTSTP 1544

Query: 1345 VWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHH--GSLSGLTTGTHEVQSLLMR 1402
            V   + +SSS  + D  S Q+ T    S+    LP+S     S    T  T  + S    
Sbjct: 1545 VTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQV 1604

Query: 1403 TGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLV 1462
            T S  ++ S + +    T+       TPS       EG   L S          + +P+ 
Sbjct: 1605 TASTEASSSTTAEGSSMTIS------TPS-------EGSPLLTSIPV-------STTPVA 1644

Query: 1463 SPSAMSSSAAGKYHFSNLVSPTNLSQFNLP--GPSMMRS 1499
            SP A + S       S +++ T +S    P  G SM  S
Sbjct: 1645 SPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTS 1683



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 262/1272 (20%), Positives = 420/1272 (33%), Gaps = 175/1272 (13%)

Query: 210  SEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNL 269
            SEAS   T      +L       S+    A     PT  PG    P           +N 
Sbjct: 2648 SEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANS 2707

Query: 270  NRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPS--PS 327
               + S   +D + P         ++S  P ++ G +  +  PS    P  S + S  P 
Sbjct: 2708 EASTLSTTPVDTSTPVT----TSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPV 2763

Query: 328  ASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEK 387
            AS    S++  V  +A  T + V  S+ A+S   +++    P S      PS   + L  
Sbjct: 2764 AS----SEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTS-----TPSETSTPLTS 2814

Query: 388  FKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLA 447
              + +   A       S+ P D                 ++ + +    +SSP  +  + 
Sbjct: 2815 MPVNHTPVASSEAGTLSTTPVD----------------TSTPVTTSTKASSSPTTAEGIV 2858

Query: 448  PPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIP 507
             P + +   S   + +                +  PV   +       P  TS   +   
Sbjct: 2859 VPISTASEGSTLLTSIP--------------VSTTPVASSEASTLSTTPVDTSIPVTTST 2904

Query: 508  KGSKT-TAAKKESL---IPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQ 563
            +GS + T A+  S+    PS    P     V TV    S  ST S      RT   + ++
Sbjct: 2905 EGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAE 2964

Query: 564  SLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQ-----LPQ 618
            + S P T   A  +S P    G      +     TM VA S   +               
Sbjct: 2965 ASSSPTT---AEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTS 3021

Query: 619  QQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEIS--GE 676
             +  S P TA             EGT +P +      T +      T    + E S    
Sbjct: 3022 TEASSSPTTA-------------EGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLST 3068

Query: 677  DPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSR 736
             P       V +            +S+  +  S  +   T     TT V    I  L++ 
Sbjct: 3069 TPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTT 3128

Query: 737  P----TPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSR 792
            P    TP+T           +    S G   P S  S            +TPL    VS 
Sbjct: 3129 PVDTSTPVT-----TSTEAHSSPTTSEGTSMPTSTPSE----------GSTPLTYMPVST 3173

Query: 793  LGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDIL-GKSLRTDDINSGYMTDGGLNLYTR 851
            +  +S  D S  +++ +D S+ V      +      G S+ T   + G MT     L + 
Sbjct: 3174 MLVVSSED-STLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEG-MTP----LTSV 3227

Query: 852  SLNRIPDTATSRDIIQ-RGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSS 910
             ++  P  ++   I+    V   T    S + SSS  +    ++   +  + +T  +   
Sbjct: 3228 PVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMP 3287

Query: 911  YSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGD---AGGKWKTVSSG 967
             S  TV S + + L T     ST   T+ S      P  D  S      + G     +  
Sbjct: 3288 VSTTTVASSETSTLSTTPADTSTPVTTY-SQASSSPPIADGTSMPTSTYSEGSTPLTNMS 3346

Query: 968  LPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKA 1027
                P  + + ++LS +        +       +  +A  S     G +    +  +G  
Sbjct: 3347 FSTTPVVSSEASTLSTTP-------VDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTT 3399

Query: 1028 PLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATIT 1087
            PL  +S+  S +    S  +     P        TS+     P+    +++ TS   T +
Sbjct: 3400 PL--ASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTS---TTS 3454

Query: 1088 SGSATLGKIPKSAAIGGKSNAG--RKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKS- 1144
             GS  L  +P S      S A     T +D S          SS TT +  S+P  +   
Sbjct: 3455 EGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGE 3514

Query: 1145 ----------STSGIPGRGGHRSSTSSIDSN--VSSKSAGA--------TTSKLREPTKI 1184
                      ST+ +        ST+ +DSN  V+S S  +        TT ++  P++ 
Sbjct: 3515 GSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEG 3574

Query: 1185 GSG-----RSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSK 1239
             S       SS    +         +V  S  V+ S    S+PT                
Sbjct: 3575 SSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVS 3634

Query: 1240 YPDIASPTFRRLFGAKAGGKSASAP---NTEGVKSSSVMPSPSTTLARQGSLESPSSG-- 1294
             P    P           G +++ P   +T  + S+ V  SP T       + +PS G  
Sbjct: 3635 TPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGST 3694

Query: 1295 ---------TGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASV----HSFTS 1341
                     T    S G    + S + + P   +T+ IS S +L S+  SV       T 
Sbjct: 3695 PLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTL 3754

Query: 1342 GGLVWAANMSSSSAGSKDTPSYQSM---TSLHTSSESIDLPLSHHGSLSGLTTGTHEVQS 1398
            G  +  +    +      TPS  S+    S+ T+SE    P     +L G TT       
Sbjct: 3755 GTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPT----TLEGTTT------- 3803

Query: 1399 LLMRTGSVRSTL 1410
            + M T S RSTL
Sbjct: 3804 MPMSTTSERSTL 3815



 Score = 68.9 bits (167), Expect = 5e-11
 Identities = 304/1521 (19%), Positives = 532/1521 (34%), Gaps = 190/1521 (12%)

Query: 203  VTHASPPSEAS--QAKTQQDMQSSLAAR--YATQSNHSGIATSQKKP--TRLPGPSRVPA 256
            V+ +  P+E +  Q  T  D ++ L +     T    S I+T    P  T  P  +   A
Sbjct: 2139 VSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEA 2198

Query: 257  AGSSSKVQGAS----NLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPP 312
              S +  +G S      +  S  F S+  +  P   +     S+    +S+ V  + +  
Sbjct: 2199 RSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEAT 2258

Query: 313  STAGQPPASAIPSPSASK---PWRSKSMN---VKHSATSTMLTVKQSSTATSPTPSSDRL 366
            S+      ++IP+ + S+   P  S  ++   V +S  ST+ T    S     T +    
Sbjct: 2259 SSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASS 2318

Query: 367  KPPVSEGVK---TAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEM 423
             PP +EG     +  S   + L +  +     A       S+ P+D       +S++G  
Sbjct: 2319 PPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSS 2378

Query: 424  EGFNSGLNSGGST---NSSPKVS-PKLAPPKAGSKNLSNKKSLLQPK-----EKEEKNRD 474
                   +   ST    S+P  S P    P   S+  ++  + +          E  +  
Sbjct: 2379 PTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSP 2438

Query: 475  KNKVCTEKPVKEEKDQVTEMA--PKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGS 532
                 T  P     +  T +A  P  T+ + S       TT     + + +S+   +  S
Sbjct: 2439 TTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTST---EASS 2495

Query: 533  KVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQAS 592
               T +  + P STAS+ S    +   S     + P+   +AS  S   P++       S
Sbjct: 2496 SPTTAEDIVVPISTASEGSTLLTSIPVS-----TTPVASPEASTLS-TTPVDSNSPVVTS 2549

Query: 593  PSGSCTMTVAQSSGQST---GNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSA 649
               S + T A+ +   T     G+  L      + P  ++ A  +     +       S 
Sbjct: 2550 TEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTST 2609

Query: 650  DSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQIS 709
            ++ +SPT        TAK     IS     +  + ++  +           S+L  T + 
Sbjct: 2610 ETSSSPT--------TAKDTSMPISTPSEVSTSLTSI--LVSTMPVASSEASTLSTTPVD 2659

Query: 710  HSTLETTFDSTVT--TEVNGRTIPNLT--SRPTPM-------------------TWRLGQ 746
              TL TT   T +  T   G ++P  T   R TP+                   T  +  
Sbjct: 2660 TRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDT 2719

Query: 747  ACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKAS 806
            + P   + +A S  +     GTS  I T       +TPL    VS L  ++  + S  ++
Sbjct: 2720 STPVTTSAEASS--SPTTAEGTSMRISTPSDG---STPLTSILVSTL-PVASSEASTVST 2773

Query: 807  SDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDII 866
            + +D S  V      S       +     + +   ++    L +  +N  P  ++    +
Sbjct: 2774 TAVDTSIPVTTSTEASSSP---TTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTL 2830

Query: 867  QRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVS-SYSNITVPSRKNTQLR 925
                 D +    +   +SS  +     +  IST    +T   S   S   V S + + L 
Sbjct: 2831 STTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLS 2890

Query: 926  TDSEKRS----TTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASL 981
            T     S    T+ E   SP   +       +  +       ++S L      AG +AS 
Sbjct: 2891 TTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVS---TPLTSILVSTVPVAGSEAST 2947

Query: 982  SVSQTGSWRRGM--SAQGGAPSRQKAGTS-ALKTPGKTDDAKASEKGKAPLKGSSLQRSP 1038
              +     R  +  SA+  +      GTS  + TPG+          + PL   S+   P
Sbjct: 2948 LSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGER---------RTPLTSMSVSTMP 2998

Query: 1039 SDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPK 1098
                 S      + P+       TS+     P+    + +  S   T + GS  L  IP 
Sbjct: 2999 --VASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPIS---TPSEGSTPLTSIPV 3053

Query: 1099 SAAIGGKSNAGRKTSLDGSQNQDDVVLH--VSSKTTLQYRSLPRPSKS-----------S 1145
            S        A   ++     N   V      SS T  +  S+P  + S           S
Sbjct: 3054 STTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVS 3113

Query: 1146 TSGIPGRGGHRSSTSSID------SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDK 1199
            T+ +        ST+ +D      ++  + S+  T+     PT   S  S+P+T      
Sbjct: 3114 TTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPV-- 3171

Query: 1200 EKEKVAVSDSESVSLSGSPKSSPT-------SASACGAQGLRQPGSKYPDIASP-TFRRL 1251
                + V  SE  +LS +P  + T       + S+  A+G   P S   +  +P T   +
Sbjct: 3172 --STMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPV 3229

Query: 1252 FGAKAGGKSASAPNTEGVKSSSVM-------PSPSTTLARQGSLESPSSGTGSMGS---- 1300
                     AS  +T  V S++ +        SP T         +PS G+  + S    
Sbjct: 3230 SNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVS 3289

Query: 1301 -AGGLSGSSSPLFNKPSDLTTDVISLSHSLASSP-----ASVHSFTSGGLVWAANMS--- 1351
                 S  +S L   P+D +T V + S + +S P     +   S  S G     NMS   
Sbjct: 3290 TTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFST 3349

Query: 1352 ----SSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGS---LSGLTTGTHEVQSLLMRTG 1404
                SS A +  T    + T + TS+E+   P +  G+    S  + GT  + S+ + T 
Sbjct: 3350 TPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTT 3409

Query: 1405 SVRS----TLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSP 1460
             V S    TLS +  +D NTL       T +S      EG     S ++ G         
Sbjct: 3410 PVVSSEVNTLS-TTPVDSNTLVTTS---TEASSSPTIAEGTSLPTSTTSEGSTPLSIMPL 3465

Query: 1461 LVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGS 1520
              +P A S ++       +  +P   S      P+     S+P   +             
Sbjct: 3466 STTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAG----------EG 3515

Query: 1521 ATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVA 1580
            +T L   P + +   S      E    S + V S + + S+++  +    +      +  
Sbjct: 3516 STPLTNMPVSTTPVAS-----SEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMST 3570

Query: 1581 SQEKVATLTSQLSANAHLVAA 1601
              E  ++LT+ L ++ ++ ++
Sbjct: 3571 PSEGSSSLTTMLLSSTYVTSS 3591



 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 260/1397 (18%), Positives = 484/1397 (34%), Gaps = 194/1397 (13%)

Query: 203  VTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSK 262
            +   +P   ++   T  +  SS      T   +S  +      T +P  S  P   S + 
Sbjct: 1356 ILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIP-VSTTPVVSSEAS 1414

Query: 263  VQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASA 322
               A+           +D + P         +++  P ++ G++     PS  G+ P  +
Sbjct: 1415 TLSAT----------PVDTSTPGT----TSAEATSSPTTAEGISIPTSTPSE-GKTPLKS 1459

Query: 323  IPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTA---PS 379
            IP  +           V +S  ST+ T    S +   T ++    P  +EG   A   PS
Sbjct: 1460 IPVSNTP---------VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPS 1510

Query: 380  GQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSS 439
               + L    +     A       S+ P+        +S++        G +   ST S 
Sbjct: 1511 EGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSE 1570

Query: 440  PKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKT 499
               +P  + P +    +S++ + L     + K +             E   +T   P + 
Sbjct: 1571 GS-TPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEG 1629

Query: 500  SKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKG 559
            S + + IP  +   A+ + S + ++       S  P +  T    S    E     T+  
Sbjct: 1630 SPLLTSIPVSTTPVASPEASTLSTTP----VDSNSPVITSTEVSSSPTPAEGTSMPTSTY 1685

Query: 560  SPSQSLSKPITMEKAS-ASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQ 618
            +  ++    IT+     ASS  + L       ++P    T T A+SS   T +    +P 
Sbjct: 1686 TEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPV--TTSTEARSS--PTTSEGTSMPN 1741

Query: 619  QQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDP 678
                      T  P        +    L S  S  S T +D S   T             
Sbjct: 1742 STPSEGTTPLTSIPV-------STTPVLSSEASTLSATPIDTSTPVTTST---------E 1785

Query: 679  ETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSR-- 736
             T    T +  +     L E M+ L  T +SH+ +  +  ST++T       P +TS   
Sbjct: 1786 ATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAV 1845

Query: 737  ---PTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRL 793
               PTP               +  S+    P  G++       S    TT +  +  + L
Sbjct: 1846 SSSPTP--------------AEGTSIATSTPSEGSTALTSIPVS----TTTVASSETNTL 1887

Query: 794  GNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKS--------LRTDDINSGYMTDGG 845
                 +      S+ +   ++V      +DG  +  S        L +  +++  +    
Sbjct: 1888 STTPAV-----TSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSE 1942

Query: 846  LNLYTRSL--NRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLN 903
            +N  + +L   R P T  S+          +    + D +S  +   S+    +++  L+
Sbjct: 1943 INTLSTTLADTRTPVTTYSQ---------ASSSPTTADGTSMPTPAYSEGSTPLTSMPLS 1993

Query: 904  TTSSVSSYSNI--TVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKW 961
            TT  VSS ++   T P   +T   T +E  S+      +  +   P E            
Sbjct: 1994 TTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSER----------- 2042

Query: 962  KTVSSGLPEDPEK--AGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTS-ALKTPGKTD- 1017
             T  +G+P       + +  +LS +   S  +  ++   + S    G+S  +  P +   
Sbjct: 2043 TTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSP 2102

Query: 1018 ---DAKASEKGKAPLKGSSLQRSPSDAGK---SSGDEGKKPPSGIGRSTATSSFGFKKPS 1071
                   S    A  + S+L  +P D+     +S +    P    G S  TS++  ++  
Sbjct: 2103 LLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTP 2162

Query: 1072 GVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKT 1131
                ++M  S+    +S  +TL   P   +    ++   ++S   S+    +     S+ 
Sbjct: 2163 ---LTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTS-MPTSTPSEG 2218

Query: 1132 TLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSN--VSSKSAGATTSKLREPTKIGSGRS 1189
            +  + S+P     ST  +        S + +D++  V++ +   ++    E T I +   
Sbjct: 2219 STPFTSMP----VSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTL 2274

Query: 1190 SPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFR 1249
            S  T   T        V++SE  +LS +P  S T            P +   + +SP   
Sbjct: 2275 SEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNT------------PFTTSTEASSPP-- 2320

Query: 1250 RLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLA--RQGSLESPSSGTGSMGSAGGLSGS 1307
                   G    ++ ++EG    + MP  +T +A     +L +  + T +  +    +GS
Sbjct: 2321 ---PTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGS 2377

Query: 1308 SSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMT 1367
            S    +  S  T+     S  L S P S     S           S A +  T    + T
Sbjct: 2378 SPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVS-----------SEASTHSTTPVDTST 2426

Query: 1368 SLHTSSESIDLPLSHHGS---LSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKK 1424
             + TS+E+   P +  G+    S  + GT  + S+ + T  V S+ + ++          
Sbjct: 2427 PVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLST-------- 2478

Query: 1425 GLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPT 1484
                TP           E   S +T           +V P + +S        S L++  
Sbjct: 2479 ----TPVDTSTPMTTSTEASSSPTTA--------EDIVVPISTASEG------STLLTSI 2520

Query: 1485 NLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEV 1544
             +S   +  P     ++ P  DS+  +   +++  SATS E      S        +  +
Sbjct: 2521 PVSTTPVASPEASTLSTTPV-DSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSM 2579

Query: 1545 HGSSLSLVSSTSSLYST 1561
              S+  L SS +S  ST
Sbjct: 2580 PVSTKPLASSEASTLST 2596



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 263/1315 (20%), Positives = 441/1315 (33%), Gaps = 172/1315 (13%)

Query: 210  SEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNL 269
            SEAS   T      +     A  S+    A     P   PG  R P    S      ++ 
Sbjct: 2943 SEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASS 3002

Query: 270  NRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSPSAS 329
               + S    D + P   +     ++S  P ++ G    +  PS  G  P ++IP  +  
Sbjct: 3003 EASTLSRTPADTSTPVTTST----EASSSPTTAEGTGIPISTPSE-GSTPLTSIPVSTTP 3057

Query: 330  KPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFK 389
                  S        S    V  +  ++SPTP+     P  +    + P           
Sbjct: 3058 VAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTP----------- 3106

Query: 390  LVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPP 449
            L     +  P    +         D +   +   E  +S   S G+       S   + P
Sbjct: 3107 LTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGT-------SMPTSTP 3159

Query: 450  KAGSKNLSNKK-SLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPK 508
              GS  L+    S +     E+       V T  PV    +  +    + TS     IP 
Sbjct: 3160 SEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTS-----IP- 3213

Query: 509  GSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKP 568
                T+   E + P +S    P S  P      S  ST   +S    TT    +++ S P
Sbjct: 3214 ----TSTPSEGMTPLTS---VPVSNTPVASSEASILSTTPVDSNTPLTTS---TEASSSP 3263

Query: 569  ITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTA 628
             T E  S  +   P EG     + P  + T+  +++S  ST       P        ++ 
Sbjct: 3264 PTAEGTSMPTS-TPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSP 3322

Query: 629  TVAPFIYRAHSENEGTALPSA---DSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRT 685
             +A          +GT++P++   +  T  T M  S +         +S    +T    T
Sbjct: 3323 PIA----------DGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVT 3372

Query: 686  VKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLG 745
                A L     E  +S+  +  S  T         TT V    +  L++ P      + 
Sbjct: 3373 TSTEASLSPTTAEG-TSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVT 3431

Query: 746  QACPRLQAGDAPSL--GAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSE 803
             +    +A  +P++  G   P S TS          + TTP+  +  S L          
Sbjct: 3432 TST---EASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTL---------- 3478

Query: 804  KASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSR 863
             +++ +D S+ V      +      +        +G   +G   L    ++  P  ++  
Sbjct: 3479 -STTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAG---EGSTPLTNMPVSTTPVASSEA 3534

Query: 864  DIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSS------YSNITVP 917
              +        VD++++  SSS +S    TL  ++T  ++T S  SS       S+  V 
Sbjct: 3535 STLST----TPVDSNTFVTSSSQASSSPATLQ-VTTMRMSTPSEGSSSLTTMLLSSTYVT 3589

Query: 918  SRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQ 977
            S + +   T S  RST   T         P E          +  T  + +P        
Sbjct: 3590 SSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVST----- 3644

Query: 978  KASLSVSQTGSWRRGMSAQGGAP--SRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQ 1035
              S+++S+ G+    +      P  +  +  +S +   G T       +G  PL      
Sbjct: 3645 -TSVTISEAGT-ASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTM--- 3699

Query: 1036 RSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGK 1095
                             P    R T++       PS V S+ + TS+ A   S SATL  
Sbjct: 3700 -----------------PVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAI--SSSATLDS 3740

Query: 1096 IPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGH 1155
               S ++  + +    T L            VS+    ++       +SST  IP     
Sbjct: 3741 TTMSVSMPMEISTLGTTIL------------VSTTPVTRF------PESSTPSIPSVYTS 3782

Query: 1156 RSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLS 1215
             S T++ + + S  +   TT+    P    S RS+ +T   T        +S SE+ +LS
Sbjct: 3783 MSMTTASEGSSSPTTLEGTTTM---PMSTTSERSTLLT---TVLISPISVMSPSEASTLS 3836

Query: 1216 GSPKSSPTS-ASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSV 1274
              P  + T   ++  A     P        S T  R           S P T  + S+++
Sbjct: 3837 TPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSER-----------STPLTTLLVSTTL 3885

Query: 1275 MPS-PSTTLARQGSLE-----SPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHS 1328
              S P  ++A    L+     +PS+ T S  +    +  S  +  + S   T +   S  
Sbjct: 3886 PTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTP 3945

Query: 1329 LASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSG 1388
            + SS A V   T+G  V    ++S+   +  T S  + TS  T+ E     ++    L+ 
Sbjct: 3946 VTSSTADVFPATTGA-VSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTY 4004

Query: 1389 LTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHS 1448
            +T  T           S   T S       +TL      +T +S             S S
Sbjct: 4005 VTMST---------APSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPS----SES 4051

Query: 1449 TGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIP 1503
            +     T +  P   P A SS+       S  V+P  ++          R+ S P
Sbjct: 4052 SRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFP 4106



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 126/609 (20%), Positives = 227/609 (37%), Gaps = 66/609 (10%)

Query: 1080 TSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLP 1139
            T S A   +G+ +   +     +   +N    TS++ S   D   +  +  T  + R+  
Sbjct: 61   TGSAANTATGTTSTNVVEPRMYLSCSTNP-EMTSIESSVTSDTPGVSSTRMTPTESRTTS 119

Query: 1140 RPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDK 1199
              +  ST+  P         SS +   S  +   T   +  P++  S  S+   V+    
Sbjct: 120  ESTSDSTTLFP---------SSTEDTSSPTTPEGTDVPMSTPSE-ESISSTMAFVSTAPL 169

Query: 1200 EKEKVAVSDSESVSLSGSPKSSPTSASACGA--QGLRQPGSKYPDIASPTFRRLFGAKAG 1257
               +   S +  V +S +P ++ T AS+     +    P S   + ++P    L    A 
Sbjct: 170  PSFEAYTSLTYKVDMS-TPLTTSTQASSSPTTPESTTIPKSTNSEGSTP----LTSMPAS 224

Query: 1258 GKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSD 1317
                ++     + ++ V  S   T++ Q S  SP++  G   S    SG S+PL   P  
Sbjct: 225  TMKVASSEAITLLTTPVEISTPVTISAQAS-SSPTTAEGPSLSNSAPSGGSTPLTRMPLS 283

Query: 1318 LTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESID 1377
            +   V S + +L+++PA+ +         +++ +++   S  T +Y   ++  TS+ +  
Sbjct: 284  VMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPAST 343

Query: 1378 LPL--SHHGSL-------SGLTTGTHEVQSL---LMRTGSVRSTLSE------------- 1412
            +P+  S   +L       S L T + E  SL      T  + STLSE             
Sbjct: 344  MPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTI 403

Query: 1413 ----SMQLDRNTLP--KKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSA 1466
                S     +T+P   K    T S   ++    ++   + ST     T   S  VS + 
Sbjct: 404  LVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTP 463

Query: 1467 MSSSAAGKYHFSNLVSPTNL--SQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSATSL 1524
            ++SS A     + + S T +  S      P     NS+P    S     +     ++ S+
Sbjct: 464  VASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPS-----EGSTPLTSMSV 518

Query: 1525 EERPRAISHSGSFR----DSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRR---- 1576
               P A S + +      D+   V  SS +  SST+   ++      SE    L      
Sbjct: 519  STMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVS 578

Query: 1577 -ELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIE 1635
              LV S E   T T+   +N  +  + E S  + T    S+  +   +    I       
Sbjct: 579  TRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVST 638

Query: 1636 MLKAQNSAA 1644
             L A + A+
Sbjct: 639  TLVASSEAS 647



 Score = 33.1 bits (74), Expect = 3.3
 Identities = 41/178 (23%), Positives = 68/178 (38%), Gaps = 19/178 (10%)

Query: 206  ASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKP----TRLPGPSRVPAAGSSS 261
            ++P   +++  T     SS    ++T    +  A +   P    T    PS  P   S  
Sbjct: 3962 STPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPS-TPRTTSRG 4020

Query: 262  KVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPAS 321
                AS L+  S    S      P         SS+  + S+ +  +  PP+    PPA 
Sbjct: 4021 CTTSASTLSATSTPHTSTSVTTRP------VTPSSESSRPST-ITSHTIPPTF---PPAH 4070

Query: 322  AIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPS 379
            +   P+ S    + S  V   A +TM T  + ST T+  P+      P +  +K+ P+
Sbjct: 4071 SSTPPTTS----ASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPT 4124


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 241/1163 (20%), Positives = 421/1163 (36%), Gaps = 173/1163 (14%)

Query: 227  ARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPN 286
            +R  T +  SG + S+    R    SR P  G S     + +L RR +S +   + +  +
Sbjct: 669  SRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSR----SRSLVRRGRSHSRTPQRRGRS 724

Query: 287  YANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATST 346
             ++   K+ S+  Q  S  N + +                S     RS+S++   S   +
Sbjct: 725  GSSSERKNKSRTSQRRSRSNSSPEMKK-------------SRISSRRSRSLSSPRSKAKS 771

Query: 347  MLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSG 406
             L++++S + +SP P      PP     + + SG      K     +RT  R  +  SS 
Sbjct: 772  RLSLRRSLSGSSPCPKQKSQTPP-----RRSRSGSSQPKAK-----SRTPPRRSRSSSSP 821

Query: 407  PSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPK 466
            P              + +       S  S++  PKV     PP+ G        S+  P+
Sbjct: 822  PP-------------KQKSKTPSRQSHSSSSPHPKVKSG-TPPRQG--------SITSPQ 859

Query: 467  EKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG 526
              E+    + + C E     E   +    P + S   S  P+   +T  ++    PS S 
Sbjct: 860  ANEQSVTPQRRSCFESSPDPE---LKSRTPSRHSCSGSSPPRVKSSTPPRQS---PSRSS 913

Query: 527  IPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGR 586
             P+     P VK  ISP     ++     ++  SPS+  S+       S S C + +E R
Sbjct: 914  SPQ-----PKVKAIISP-----RQRSHSGSSSPSPSRVTSRTTPRRSRSVSPC-SNVESR 962

Query: 587  EAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTAL 646
               + S SGS +                + P +Q HS     +++P+         G   
Sbjct: 963  LLPRYSHSGSSSPDTKVKP---------ETPPRQSHS----GSISPYPKVKAQTPPG--- 1006

Query: 647  PSADSCTSPTKMDLSYSKTAKQC---LEEISGEDPETRRMRTVKNIADLR-----QNLEE 698
            PS     SP   + S     + C   L   +G    T    +   ++ L+     Q   +
Sbjct: 1007 PSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD 1066

Query: 699  TMSSLRGTQI--SHSTLETTFDSTVTTEVNGRT-----IPNLTSRPTPMTWRLGQ--ACP 749
              S     ++  SHS   +    + T+   GR+     +  L SR +P+    G+  A P
Sbjct: 1067 HRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASR-SPIRQDRGEFSASP 1125

Query: 750  RLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRA-AVSRLGNMSQIDMSEKASSD 808
             L++G +P       +S +S +   D +  +  + L  A +  ++    Q D +      
Sbjct: 1126 MLKSGMSPEQSRF--QSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQ 1183

Query: 809  LDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLN-RIPDTATSRDIIQ 867
             D  S   V        +   +LRT        +  G +  T+  N  +P ++   ++++
Sbjct: 1184 KDKFSPFPVQDRPESSLVFKDTLRTPPRE---RSGAGSSPETKEQNSALPTSSQDEELME 1240

Query: 868  RGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVP-SRKNTQLRT 926
                   V   S + +  + S LS  L  +ST +  ++  V     +++   +  +Q   
Sbjct: 1241 -------VVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASL 1293

Query: 927  DSEKRSTTDETWDSPEELKKPEE---------------DFDSHGDAGGKWKT-VSSGLPE 970
            ++ +  +   +W  P    + +E               +F + G  G +  T  SS + E
Sbjct: 1294 EAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKE 1353

Query: 971  D-----PEKAGQKASLSVSQTGSWRRGMSA---------QGGAPSRQKAGTSALKTPGKT 1016
            D       +     SL + +  +   G S+         + G  S Q   +  L    +T
Sbjct: 1354 DLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRT 1413

Query: 1017 DDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGI--GRSTATSSFGFK----KP 1070
               + S    +P     L R+PS   +S    G +  SG     S + SS G K     P
Sbjct: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP 1473

Query: 1071 SGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSK 1130
            S   S    +     +        + P S  +  K    ++    GS++  D       +
Sbjct: 1474 SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQR-ERSGSESSVD-------Q 1525

Query: 1131 TTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSS 1190
             T+    L + S+S +S         S     +S+ S  S   T + LR+ ++ G   SS
Sbjct: 1526 KTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSG---SS 1582

Query: 1191 PVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRR 1250
            P         K +++   S S S S   K  P +A    +     P  K P   +   R 
Sbjct: 1583 PEV-----DSKSRLSPRRSRSGS-SPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS 1636

Query: 1251 LFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSP 1310
              G+ + G+  S   +   +SS   P P +  AR+GS  SP   T S       S  SSP
Sbjct: 1637 RSGSSSKGRGPSPEGSSSTESSPEHP-PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSP 1695

Query: 1311 LFNKPSDLTTDVISLSHSLASSP 1333
               + + L+      S S +SSP
Sbjct: 1696 ELTRKARLS----RRSRSASSSP 1714



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 247/1129 (21%), Positives = 379/1129 (33%), Gaps = 187/1129 (16%)

Query: 210  SEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNL 269
            S  S+AK++  ++ SL+         S     QK  T    P R   +GSS     +   
Sbjct: 764  SPRSKAKSRLSLRRSLSG--------SSPCPKQKSQT----PPRRSRSGSSQPKAKSRTP 811

Query: 270  NRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPAS-AIPSPSA 328
             RRS+S +S     PP       K  SK P   S  + +  P   +G PP   +I SP A
Sbjct: 812  PRRSRSSSS-----PP------PKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQA 860

Query: 329  SK----PWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSM 384
            ++    P R               T  + S + S  P      PP     + +PS   S 
Sbjct: 861  NEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPP-----RQSPSRSSSP 915

Query: 385  LEKFKLV-----NARTALRPPQPPSSGPSDGGKDDDAFSESGEMEG-FNSGLNSGGSTNS 438
              K K +      + +    P P         +   + S    +E       +  GS++ 
Sbjct: 916  QPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSP 975

Query: 439  SPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEK--DQVTEMAP 496
              KV P+  P ++ S ++S       PK K +     +   ++ P  +EK  D + +  P
Sbjct: 976  DTKVKPETPPRQSHSGSISP-----YPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCP 1030

Query: 497  KKTSKIA---SLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEK 553
               S  A   S  P G          L   S   P   S   + +   S   + S +S+ 
Sbjct: 1031 GSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKS 1090

Query: 554  FRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGA 613
              + KG  S+S S P+T E AS S      + R    ASP     M+  QS  QS  +  
Sbjct: 1091 QTSPKGGRSRS-SSPVT-ELASRSPIR---QDRGEFSASPMLKSGMSPEQSRFQSDSSSY 1145

Query: 614  VQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEI 673
              +            T       A S+ +    P  D+  SP +    +S    Q   E 
Sbjct: 1146 PTVDSNSLLGQSRLET-------AESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPES 1198

Query: 674  S-----------------GEDPETRRMRTVKNIADLRQNLEETMSSLR---GTQISHSTL 713
            S                 G  PET+   +    +   + L E +       G  +SH + 
Sbjct: 1199 SLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSS 1258

Query: 714  ETTFDSTVTTEVNGRTIPNLTSRPT-PMTWRLGQACPRLQAGDAPSLGA--GYPR-SGTS 769
            E    ST   E +    P +  RP   +T    Q+   L+A + PS+ +  G P  S   
Sbjct: 1259 ELKEMSTSNFESS----PEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEH 1314

Query: 770  RFIHTDPSRF-MYTTPLRRAAVSRLGNMSQIDMSEKASSDLD----MSSEVDVGGYMSDG 824
            + +   P R   + +PL       LG       S +   DL+       E D    M + 
Sbjct: 1315 KELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQ 1374

Query: 825  DILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSS 884
                    + +++   +   G++              S   I   V D      S + SS
Sbjct: 1375 STRSSGHSSSELSPDAVEKAGMS--------------SNQSISSPVLDAVPRTPSRERSS 1420

Query: 885  SVSSG-LSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQ---------LRTDSEKRSTT 934
            S SS  + D L    +    + SS         PSR +            RT S  RS  
Sbjct: 1421 SASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSEC 1480

Query: 935  DETWDSPE-----ELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSW 989
            D    SPE     +  +P     S  +   K  T        P++    +  SV Q    
Sbjct: 1481 DS---SPEPKALPQTPRPRSRSPSSPELNNKCLT--------PQRERSGSESSVDQKTVA 1529

Query: 990  RRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEG 1049
            R  +  +  + S Q+       +P +  ++ +S   KA  +    QRS S +      + 
Sbjct: 1530 RTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS 1589

Query: 1050 KKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAG 1109
            +  P    RS + SS   K        A   S  +      A      +S +  G S+ G
Sbjct: 1590 RLSPR---RSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS--GSSSKG 1644

Query: 1110 RKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSK 1169
            R  S +GS + +    H              P KS T+    R G RSS           
Sbjct: 1645 RGPSPEGSSSTESSPEH--------------PPKSRTA----RRGSRSSPEP-------- 1678

Query: 1170 SAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACG 1229
                  +K R P +  S RSSP    +    +             S S  SSP + S   
Sbjct: 1679 -----KTKSRTPPRRRSSRSSPELTRKARLSRR------------SRSASSSPETRSRTP 1721

Query: 1230 AQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSP 1278
             +  R P    P+ A  +      +    +SAS+P T+        PSP
Sbjct: 1722 PRHRRSPSVSSPEPAEKS-----RSSRRRRSASSPRTKTTSRRGRSPSP 1765



 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 303/1428 (21%), Positives = 472/1428 (33%), Gaps = 225/1428 (15%)

Query: 228  RYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGAS-NLNRRSQSFNSIDKNKPPN 286
            R A    H     ++KK  RL    R     S S V G+S +  RR++         P  
Sbjct: 115  RPAVTETHQLAELNEKKNERL----RAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170

Query: 287  YANGNEKDSSKGPQSSSGVNGNVQPPSTAGQP--PASAIPSPSASKPWRSKSMNVKHSAT 344
            Y+   E  SS+ P          +      +   P       S  K  RS+S + K    
Sbjct: 171  YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHR 230

Query: 345  STMLTVKQSST--------ATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTA 396
            S     K+ S         +T+P P S R     S    ++    +S           TA
Sbjct: 231  SPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTA 290

Query: 397  LRPPQP-PSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKN 455
            L    P P+SG    G+ D  FSE G             +T++    SP+ A  +  S  
Sbjct: 291  LAGRSPSPASGRR--GEGDAPFSEPG-------------TTSTQRPSSPETATKQPSS-- 333

Query: 456  LSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAA 515
                     P E ++K++ K K  T      E+       P  T  +A            
Sbjct: 334  ---------PYEDKDKDK-KEKSATRPSPSPERSSTGPEPPAPTPLLAE----------- 372

Query: 516  KKESLIPSSSGIPKPGSKVPTVKQTISPGSTAS--------KESEKFRTTKGSPSQSLSK 567
                      G P+P +  P  ++ ++P S AS        K  EK   +  S S   S 
Sbjct: 373  -------RHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425

Query: 568  PITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNT 627
              T     ASS P      E+ + +P+      ++ SS  S      +  + + HSH   
Sbjct: 426  QPTKVSRHASSSP------ESPKPAPAPGSHREIS-SSPTSKNRSHGRAKRDKSHSH--- 475

Query: 628  ATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKT-----AKQCLEEISGEDPETR- 681
                P      S +  TA        +PTK   S S++     ++          P+ R 
Sbjct: 476  ---TPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRG 532

Query: 682  RMRTVKNIADLR----QNLEETMSSLRGTQISHSTLETTFDSTVTTEVNG----RTIPNL 733
            R R+ +     R    Q    + S+ RG   S S        + T    G    RT    
Sbjct: 533  RSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARR 592

Query: 734  TSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRL 793
             SR    T R  ++    + G + S      RS T   +     R    +P RR+  SR 
Sbjct: 593  RSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR---RRSRSRSPARRSGRSRS 649

Query: 794  GNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSL 853
               ++   S   +      S        S     G+S        G           RS 
Sbjct: 650  RTPARRGRSRSRTPARRGRSRSRTPARRS-----GRSRSRTPARRG-----------RSR 693

Query: 854  NRIP--DTATSRDIIQRG-VHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSS 910
            +R P    + SR +++RG  H  T        SSS     S T    S  + +     S 
Sbjct: 694  SRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSR 753

Query: 911  YSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPE 970
             S+    S  + + +  S        +  SP   +K +           + K  S   P 
Sbjct: 754  ISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR 813

Query: 971  DPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLK 1030
                +        S+T S R+  S+    P + K+GT   +  G     +A+E+   P +
Sbjct: 814  RSRSSSSPPPKQKSKTPS-RQSHSSSSPHP-KVKSGTPPRQ--GSITSPQANEQSVTPQR 869

Query: 1031 GSSLQRSPSDAGKS-----SGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGAT 1085
             S  + SP    KS         G  PP  +  ST       +  S       I S    
Sbjct: 870  RSCFESSPDPELKSRTPSRHSCSGSSPPR-VKSSTPPRQSPSRSSSPQPKVKAIISPRQR 928

Query: 1086 ITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSS 1145
              SGS++    P  + +  ++   R  S             VS  + ++ R LPR S S 
Sbjct: 929  SHSGSSS----PSPSRVTSRTTPRRSRS-------------VSPCSNVESRLLPRYSHSG 971

Query: 1146 TSG--------IPGRGGHRSSTSSIDSNVSSKSAGATTSKLREP-----TKIGSGRSSPV 1192
            +S          P R  H  S S      +    G + S  + P     +K    +S P 
Sbjct: 972  SSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPG 1031

Query: 1193 TVNQTDKEKEKVAVSDS----ESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTF 1248
            +++     K      +S     S+ L G  ++SP   S   +  +RQ  S+ P + S   
Sbjct: 1032 SLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQS--- 1088

Query: 1249 RRLFGAKAGGKSASAPNTE-----------GVKSSSVM----PSPSTTLARQGSLESPSS 1293
            +     K G   +S+P TE           G  S+S M     SP  +  +  S   P+ 
Sbjct: 1089 KSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTV 1148

Query: 1294 GTGS-MGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSS 1352
             + S +G +   +  S      P                SP  V       LV+   + +
Sbjct: 1149 DSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRT 1208

Query: 1353 -----SSAGSKDTPSYQSMTSLHTSSESIDLP-------------LSHHGS-LSGLTTGT 1393
                 S AGS      Q+ ++L TSS+  +L              LSH  S L  ++T  
Sbjct: 1209 PPRERSGAGSSPETKEQN-SALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSN 1267

Query: 1394 HEVQSLLMRTGSVRSTLSESM---QLDRNTLPKKGLRY-TPSSRQANQEEGKEWLRSHST 1449
             E    +    +V  TL +S     L+   +P     +  P     ++E     LR +S 
Sbjct: 1268 FESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSF 1327

Query: 1450 GGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSF 1509
            G   +  N  PL +      S+  K               +L GP + +  +    D S 
Sbjct: 1328 GSPLEFRNSGPLGTEMNTGFSSEVKE--------------DLNGPFLNQLET----DPSL 1369

Query: 1510 DLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSS 1557
            D+ + S      +S E  P A+  +G    S + +    L  V  T S
Sbjct: 1370 DMKEQSTRSSGHSSSELSPDAVEKAG--MSSNQSISSPVLDAVPRTPS 1415



 Score = 58.5 bits (140), Expect = 7e-08
 Identities = 279/1443 (19%), Positives = 477/1443 (33%), Gaps = 165/1443 (11%)

Query: 200  QQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGS 259
            + R T  +P S  +   T  D  SS      T  + S  A ++   T L G S  PA+G 
Sbjct: 247  RSRSTTPAPKSRRAHRSTSADSASSSD----TSRSRSRSAAAKTHTTALAGRSPSPASGR 302

Query: 260  SSK-----VQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPST 314
              +      +  +   +R  S  +  K     Y    +KD  K  +S++  + + +  ST
Sbjct: 303  RGEGDAPFSEPGTTSTQRPSSPETATKQPSSPY---EDKDKDKKEKSATRPSPSPERSST 359

Query: 315  AGQPPA---------SAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDR 365
              +PPA            P P A+ P   + +N    A+ T       S    P  SS  
Sbjct: 360  GPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSE 419

Query: 366  LKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRP--PQPPSSGPSDG-GKDDDAFSESGE 422
              PP  +  K +     S  E  K   A  + R     P S   S G  K D + S +  
Sbjct: 420  SSPPSPQPTKVSRHASSSP-ESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPS 478

Query: 423  MEGFNSGLNSGGSTNSSPKVSP-KLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTE 481
                 S   +      S   +P K    ++ S      +S  +        R       +
Sbjct: 479  RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538

Query: 482  KPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPG--------SK 533
            +P    + + T+   +  S         S  T  +  S  P+  G  +          S+
Sbjct: 539  RP-GWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSR 597

Query: 534  VPTVKQTISP-----GSTASKESEKFRTTKGSPSQSLSK---PITMEKASASSCPAPL-E 584
             PT +++ S      G + S+   + R+   SP +  S+   P      S S  PA    
Sbjct: 598  TPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGR 657

Query: 585  GREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYR---AHSEN 641
             R    A    S + T A+ SG+S      +  + +  +     + +  + R   +HS  
Sbjct: 658  SRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717

Query: 642  EGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMS 701
                  S  S     K   S  ++      E+      +RR R+   ++  R   +  +S
Sbjct: 718  PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS---LSSPRSKAKSRLS 774

Query: 702  SLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGA 761
              R    S    +    +      +G + P   SR  P   R   + P  Q    PS   
Sbjct: 775  LRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR-- 832

Query: 762  GYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYM 821
               +S +S   H  P     T P + +  S   N   +    ++  +     E+      
Sbjct: 833  ---QSHSSSSPH--PKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPEL------ 881

Query: 822  SDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWD 881
                      RT   +S   +       +    + P  ++S     + +      + S  
Sbjct: 882  --------KSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS 933

Query: 882  DSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSP 941
             S S S   S T    S        SVS  SN+     ++  L   S   S++ +T   P
Sbjct: 934  SSPSPSRVTSRTTPRRSR-------SVSPCSNV-----ESRLLPRYSHSGSSSPDTKVKP 981

Query: 942  EELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKA---------SLSVSQTGSWRRG 992
            E   +      SH  +   +  V +  P  P  +G K+         SL  S  GS    
Sbjct: 982  ETPPR-----QSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLC 1036

Query: 993  MSAQGGAPSRQKA-GTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKK 1051
               +   P  +   G S+L+  G++   + S   ++      +++S S++          
Sbjct: 1037 AGVKSSTPPGESYFGVSSLQLKGQS---QTSPDHRSDTSSPEVRQSHSESPSLQSKSQTS 1093

Query: 1052 PPSGIGRSTA-----TSSFGFKKPSGVGSSAMITSSGAT-----ITSGSATLGKIPKSAA 1101
            P  G  RS++      S    ++  G  S++ +  SG +       S S++   +  ++ 
Sbjct: 1094 PKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSL 1153

Query: 1102 IGGK--SNAGRKTSLDGSQNQDDVVLHVSSK-------------TTLQYRSLPRPSKSST 1146
            +G      A  K  +     +D        K             ++L ++   R      
Sbjct: 1154 LGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRER 1213

Query: 1147 SGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPT-KIGSGRSSPVTVNQTDKEKEKVA 1205
            SG       +   S++ ++   +       K  EP  +I S  SS +    T   +    
Sbjct: 1214 SGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPE 1273

Query: 1206 VSDSESVSLSGSPKSSPTSASACGAQGLRQP------GSKYPDIA-SPTFRRLFGAKAGG 1258
            V +  +VSL+     S  S  A     +           ++ +++ SP     FG+    
Sbjct: 1274 VEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEF 1333

Query: 1259 KSASAPNTE--------------GVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGL 1304
            +++    TE              G   + +   PS  +  Q +  S  S +     A   
Sbjct: 1334 RNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEK 1393

Query: 1305 SGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANM---SSSSAGSKDTP 1361
            +G SS      S    D +  + S   S ++       GL    +    S SS G +D  
Sbjct: 1394 AGMSSN--QSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGS 1451

Query: 1362 SYQSMTSLHTSSESI-DLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNT 1420
               S  SL  SS  + D+P +     S   +        L +T   RS    S +L+   
Sbjct: 1452 GTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEP--KALPQTPRPRSRSPSSPELNNKC 1509

Query: 1421 LPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNL 1480
            L  +  R    S    +   +  L   S  G     +  P  SP   S S +        
Sbjct: 1510 LTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDS-------- 1561

Query: 1481 VSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDS 1540
             SP + ++   P     RS S P  DS   L       GS+  ++++PRA   + S  DS
Sbjct: 1562 -SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDS 1620

Query: 1541 MEE 1543
              E
Sbjct: 1621 SPE 1623



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 188/839 (22%), Positives = 298/839 (35%), Gaps = 130/839 (15%)

Query: 972  PEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKG 1031
            P + G+  S + ++ G  R    A+    SR +      ++  +T     S       +G
Sbjct: 652  PARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRG 711

Query: 1032 SSLQRSPSDAGKSSGDEGKKPPSGIG--RSTATSSFGFKKPSGVGSSAMITSSGATITSG 1089
             S  R+P   G+S     +K  S     RS + SS   KK              + I+S 
Sbjct: 712  RSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK--------------SRISSR 757

Query: 1090 SATLGKIPKSAAIGGKSNAGRKTSLDG--------SQNQDDVVLHVSSKTTLQYRSLPRP 1141
             +     P+S A   KS    + SL G        SQ         SS+   + R+ PR 
Sbjct: 758  RSRSLSSPRSKA---KSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR 814

Query: 1142 SKSST-------SGIPGRGGHRSST--SSIDSNVSSKSAGATTSKLRE----PTKIGSGR 1188
            S+SS+       S  P R  H SS+    + S    +    T+ +  E    P +     
Sbjct: 815  SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874

Query: 1189 SSP-VTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPT 1247
            SSP   +      +   + S    V  S  P+ SP+ +S+        P  K   I SP 
Sbjct: 875  SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS--------PQPKVKAIISPR 926

Query: 1248 FRRLFGAKAGGKSASAPNTEGVKSSSVMPSPST------TLARQGSLESPSSGTGSMGSA 1301
             R   G+ +   S     T   +S SV P  +         +  GS    +         
Sbjct: 927  QRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPR 986

Query: 1302 GGLSGSSSPLFNKPSDLTTDVISLSHSLASSPA-----SVHSFTSGGLVWAANMSSSSAG 1356
               SGS SP + K    T    SLS S +  P      S+     G L   A + SS+  
Sbjct: 987  QSHSGSISP-YPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPP 1045

Query: 1357 SKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQ- 1415
             +   SY  ++SL    +S   P   H S     T + EV+     + S++S    S + 
Sbjct: 1046 GE---SYFGVSSLQLKGQSQTSP--DHRS----DTSSPEVRQSHSESPSLQSKSQTSPKG 1096

Query: 1416 -LDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGK 1474
               R++ P   L      RQ   E     +        Q          P+  S+S  G+
Sbjct: 1097 GRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQ 1156

Query: 1475 YHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLY-----DDSQLCGSATSLEERPR 1529
               S L +  +  +  LP P    + S P Q   F  +      +S L    T L   PR
Sbjct: 1157 ---SRLETAESKEKMALP-PQEDATASPPRQKDKFSPFPVQDRPESSLVFKDT-LRTPPR 1211

Query: 1530 AISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLT 1589
              S +GS  ++ E+            S+L ++++++   E + K       S+E    + 
Sbjct: 1212 ERSGAGSSPETKEQ-----------NSALPTSSQDEELMEVVEK-------SEEPAGQIL 1253

Query: 1590 SQLSANAHLVAA--FEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAA 1647
            S LS+    ++   FE S         SLT+   Q ++ L    E +E+          +
Sbjct: 1254 SHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASL----EAVEV---------PS 1300

Query: 1648 IQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWVNSRGS 1707
            +  +  GP   P       +H   S    NS    +S GS  +  +             S
Sbjct: 1301 MASSWGGPHFSP-------EHKELS----NSPLRENSFGSPLEFRNSGPLGTEMNTGFSS 1349

Query: 1708 ELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNAGDCGSASMKPSQSASA 1766
            E++      F  +  T P  S    E+ T SS  +S +L  +A +   A M  +QS S+
Sbjct: 1350 EVKEDLNGPFLNQLETDP--SLDMKEQSTRSSGHSSSELSPDAVE--KAGMSSNQSISS 1404



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 237/1199 (19%), Positives = 415/1199 (34%), Gaps = 167/1199 (13%)

Query: 209  PSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASN 268
            PS    + T+   +    +R A + + S    S +  T+   P R  ++ SS ++   + 
Sbjct: 1647 PSPEGSSSTESSPEHPPKSRTARRGSRS----SPEPKTKSRTPPRRRSSRSSPELTRKAR 1702

Query: 269  LNRRSQSFNSIDKNK---PPNYANGNEKDSSKGPQS--SSGVNGNVQPPSTAGQPPASAI 323
            L+RRS+S +S  + +   PP +       S +  +   SS    +   P T         
Sbjct: 1703 LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRS 1762

Query: 324  PSPSASKPWRSKSMNVKHSATSTMLTVKQ-SSTATSPTPSSDRLKPPVS---EGVKTAPS 379
            PSP      RS+S + +    +T    +  SS +TS      R +  V+    G     S
Sbjct: 1763 PSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS 1822

Query: 380  GQKSMLEKFKLVNARTALRPPQPPSS--------GPSDGGKDDDAFSESGEMEGFN---- 427
               +  E  +  + R   R   PP+S         P+   +     S +      +    
Sbjct: 1823 RSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPL 1882

Query: 428  -------------SGLNSGGSTNSSPKVSPKLAPP------KAGSKNLSNKKSLLQPKEK 468
                         S   S   T+ + + S   A P      ++ +  ++ ++S  +    
Sbjct: 1883 ISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTT 1942

Query: 469  EEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIP 528
              ++R +    T +  +     VT    +  +   +     S+T+   +      +S + 
Sbjct: 1943 RRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVT 2002

Query: 529  KPGSKVPTVKQTISPGSTASKESEKFRTTKGSP------SQSLSKPITMEKASASSCPAP 582
            +  S+  T   T     + +  + + R+   +P      S+S S P+ + + S S  P  
Sbjct: 2003 RRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRS-PLAIRRRSRSRTPRT 2061

Query: 583  LEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENE 642
              G+ +   SP      + + SS  S  + +   P  + HS   T  VA    R    + 
Sbjct: 2062 ARGKRSLTRSPPAIRRRSASGSS--SDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSR 2119

Query: 643  GTALPS-ADSCTSPTKMD-LSYSKTAKQCLEEISG--------EDPETRRMRTVKNIADL 692
             +  P+  D C SP  ++ L  S+T    L++  G          P+ +R    +N A  
Sbjct: 2120 PSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQS 2179

Query: 693  RQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQ 752
            R  L  T  SL GT     ++     +   ++V    +P ++ R  P    L    P   
Sbjct: 2180 RIALALTAISL-GTARPPPSMSAAGLAARMSQVPA-PVPLMSLRTAPAA-NLASRIPAAS 2236

Query: 753  AGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSD--LD 810
            A       A  P   T+  ++   SR    TP   AA++     + +  S    +D    
Sbjct: 2237 AAAMNLASARTPAIPTA--VNLADSR----TPAAAAAMNLASPRTAVAPSAVNLADPRTP 2290

Query: 811  MSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDII-QRG 869
             +  V++ G  +   +   SL      +G  T      Y  S +R P    S +++  R 
Sbjct: 2291 TAPAVNLAGARTPAALAALSL------TGSGTPPTAANYPSS-SRTPQAPASANLVGPRS 2343

Query: 870  VHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSE 929
             H           ++ V+   S T   ++   L +     + S   + S +      +  
Sbjct: 2344 AH----------ATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERV 2393

Query: 930  KRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSW 989
               T+    D       P         A  + +  S   P    + GQ  S S+      
Sbjct: 2394 SGRTSPPLLDRARSRTPP--------SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQ- 2444

Query: 990  RRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSG--- 1046
             +  S    A S Q     A  TP           G   L   ++  + S AG  +G   
Sbjct: 2445 DQPRSPVPSAFSDQSRCLIAQTTP---------VAGSQSLSSGAVATTTSSAGDHNGMLS 2495

Query: 1047 -DEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGK 1105
                  P S +G   A  S G ++PS + +        ++ +S S+       S++    
Sbjct: 2496 VPAPGVPHSDVGEPPA--STGAQQPSALAALQPAKERRSSSSSSSS-------SSSSSSS 2546

Query: 1106 SNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGI---------PGRGGHR 1156
            S++   +S  GS + D     +  +  +  + +P P+ +    +         P +   R
Sbjct: 2547 SSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRR 2606

Query: 1157 SSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSG 1216
            SS+SS  S+ SS S+ +++S         S  SS                S S S S S 
Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSS-------SSSSSS----------------SSSSSSSSSS 2643

Query: 1217 SPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAP--NTEGVKSSSV 1274
            S  SSP+ A   G Q L +P S  P    P  RR        +S   P  +    +S S 
Sbjct: 2644 SSSSSPSPAKP-GPQALPKPAS--PKKPPPGERR-------SRSPRKPIDSLRDSRSLSY 2693

Query: 1275 MPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSP 1333
             P      + Q S     S +   GS  G  G S    +K    T     + H  + SP
Sbjct: 2694 SPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 93/403 (23%), Positives = 142/403 (35%), Gaps = 68/403 (16%)

Query: 202  RVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSS 261
            R  HA+ P   + ++T        AA  A  S  S           L  P RVP + +  
Sbjct: 2342 RSAHATAPVNIAGSRT--------AAALAPASLTSARMAPALSGANLTSP-RVPLS-AYE 2391

Query: 262  KVQGASN--LNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPP 319
            +V G ++  L  R++S        PP+  + +   S + P  SS +    Q PS +  PP
Sbjct: 2392 RVSGRTSPPLLDRARS------RTPPSAPSQSRMTSERAPSPSSRMG---QAPSQSLLPP 2442

Query: 320  ASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSS-----DRLKPPVSEGV 374
            A   P       +  +S  +    T    +   SS A + T SS       L  P + GV
Sbjct: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP-APGV 2501

Query: 375  KTAPSGQKSMLEKFKLVNARTALRPPQPP-SSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
              +  G+       +  +A  AL+P +   SS  S       + S S      +SG +S 
Sbjct: 2502 PHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561

Query: 434  GSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
             S  SS  V P++A  +  S                             P    K+ V E
Sbjct: 2562 DSEGSSLPVQPEVALKRVPS-----------------------------PTPAPKEAVRE 2592

Query: 494  MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEK 553
              P +        P  +K    K+ S   SSS      S   +   + S  S++S  S  
Sbjct: 2593 GRPPE--------PTPAKR---KRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641

Query: 554  FRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGS 596
              ++  SPS +   P  + K ++   P P E R      P  S
Sbjct: 2642 SSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDS 2684



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 99/446 (22%), Positives = 163/446 (36%), Gaps = 72/446 (16%)

Query: 1075 SSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKT-------SLDGSQNQDDVVLHV 1127
            ++AM  +S  T  + SA     P++      + AG +T       SL GS        + 
Sbjct: 2265 AAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYP 2324

Query: 1128 SSKTTLQY---RSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKS-----AGATTSKLR 1179
            SS  T Q     +L  P  +  +      G R++ +   ++++S       +GA  +  R
Sbjct: 2325 SSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPR 2384

Query: 1180 EPTKIG---SGRSSPVTVNQTDKEKEKVAVSDSESVS-LSGSPKS----SPTSASACGAQ 1231
             P       SGR+SP  +++        A S S   S  + SP S    +P+ +    AQ
Sbjct: 2385 VPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQ 2444

Query: 1232 GLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESP 1291
               QP S  P   S   R L       ++     ++ + S +V  + S+     G L  P
Sbjct: 2445 D--QPRSPVPSAFSDQSRCLIA-----QTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP 2497

Query: 1292 SSGT--GSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAAN 1349
            + G     +G     +G+  P               S   A  PA     +S     +++
Sbjct: 2498 APGVPHSDVGEPPASTGAQQP---------------SALAALQPAKERRSSSSS---SSS 2539

Query: 1350 MSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRST 1409
             SSSS+ S  + S  S  S  + SE   LP+              + +  L R  S    
Sbjct: 2540 SSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV--------------QPEVALKRVPSPTPA 2585

Query: 1410 LSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSS 1469
              E+++  R   P      TP+ R+           S S+     + + S   S S+ SS
Sbjct: 2586 PKEAVREGRPPEP------TPAKRKRRSSSSSS--SSSSSSSSSSSSSSSSSSSSSSSSS 2637

Query: 1470 SAAGKYHFSNLVSPTNLSQFNLPGPS 1495
            S++     S+  SP       LP P+
Sbjct: 2638 SSSSSSSSSSSPSPAKPGPQALPKPA 2663



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 56/246 (22%), Positives = 91/246 (36%), Gaps = 20/246 (8%)

Query: 204  THASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKV 263
            T A  PS  +  +  ++ +SS ++  ++ S+ S  ++S    +   G S   + GSS  V
Sbjct: 2513 TGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS--GSSSSDSEGSSLPV 2570

Query: 264  QGASNLNRRSQSF----NSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPP 319
            Q    L R          ++ + +PP       K  S    SSS         S++    
Sbjct: 2571 QPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS---------SSSSSSS 2621

Query: 320  ASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPS 379
            +S+  S S+S    S S +   S++S+    K    A  P P+S + KPP  E    +P 
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQAL-PKPASPK-KPPPGERRSRSPR 2679

Query: 380  GQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSS 439
                 L   + ++     R    P   P D      + SE G   G      S       
Sbjct: 2680 KPIDSLRDSRSLSYSPVERRRPSPQPSPRD---QQSSSSERGSRRGQRGDSRSPSHKRRR 2736

Query: 440  PKVSPK 445
               SP+
Sbjct: 2737 ETPSPR 2742



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 187/905 (20%), Positives = 317/905 (35%), Gaps = 134/905 (14%)

Query: 969  PEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAP 1028
            P+ PEK  Q +S   S              +P   K    A  +P      ++ +   AP
Sbjct: 406  PKSPEKLPQSSSSESSPP------------SPQPTKVSRHASSSP------ESPKPAPAP 447

Query: 1029 LKGSSLQRSPSDAGKSSGDEGKKPPS---------GIGRSTATSSFGFKK---PSGVGSS 1076
                 +  SP+   +S G   K+  S         G  RS AT+  G  +   P+  G S
Sbjct: 448  GSHREISSSPTSKNRSHG-RAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHS 506

Query: 1077 AMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYR 1136
               + S     S SA      +S    G+S + ++     S+N        S++    + 
Sbjct: 507  R--SRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHS 564

Query: 1137 SLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQ 1196
              P     S S  P R G   S +       S++     S+ R P + G  RS      +
Sbjct: 565  RSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRR 624

Query: 1197 TDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPG------SKYPDIASPTFRR 1250
            +         S S S +       S T A   G    R P       S+ P   S   R 
Sbjct: 625  SRTRSPVRRRSRSRSPARRSGRSRSRTPARR-GRSRSRTPARRGRSRSRTPARRSGRSRS 683

Query: 1251 LFGAKAGGKSASAPNTEGVKSSSVM---PSPSTTLARQGSLESPSSGTGSMGSAGGLSGS 1307
               A+ G   +  P     +S S++    S S T  R+G   S S       ++   S S
Sbjct: 684  RTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRS 743

Query: 1308 SSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMT 1367
            +S    K S +++     S SL+S  +   S  S        +  S +GS   P  +S T
Sbjct: 744  NSSPEMKKSRISS---RRSRSLSSPRSKAKSRLS--------LRRSLSGSSPCPKQKSQT 792

Query: 1368 SLHTSSESIDLPLSHHGS---LSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKK 1424
                S      P +   +    S  ++     Q     +    S+ S   ++   T P++
Sbjct: 793  PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852

Query: 1425 G---------LRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPS-----AMSSS 1470
            G            TP  R   +      L+S +      +G+  P V  S     + S S
Sbjct: 853  GSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRS 912

Query: 1471 AAGKYHFSNLVSPTNLSQ--FNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSATSLEER- 1527
            ++ +     ++SP   S    + P PS + S + P +         S+     +++E R 
Sbjct: 913  SSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR---------SRSVSPCSNVESRL 963

Query: 1528 -PRAISHSGSFRDSME--------EVHGSSLS----LVSSTSSLYSTAEEKAHSEQIHKL 1574
             PR  SHSGS     +        + H  S+S    + + T    S +  K+   Q  K 
Sbjct: 964  LPR-YSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQ-EKS 1021

Query: 1575 RRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETI 1634
            +  LV S     +L + + ++     ++   + ++  + QS T    + ++   E+R++ 
Sbjct: 1022 KDSLVQSCPGSLSLCAGVKSSTPPGESY-FGVSSLQLKGQSQTSPDHRSDTSSPEVRQSH 1080

Query: 1635 EMLKAQNSAAQAAIQGALNGPDHPPKDLRIR---RQHSSESVSSINSATSHSSIGSGNDA 1691
                +  S +Q + +G  +    P  +L  R   RQ   E  +S    +  S   S   +
Sbjct: 1081 SESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQS 1140

Query: 1692 DSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPS--------------SHSDIEELTD 1737
            DS        V+S     +S  + A  K+K   PP               S   +++  +
Sbjct: 1141 DSSSYPT---VDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPE 1197

Query: 1738 SSLPASPKL---PHNAGDCGSASMKPSQSAS------------AICECTEAEAEIILQLK 1782
            SSL     L   P      GS+     Q+++             + +  E   +I+  L 
Sbjct: 1198 SSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLS 1257

Query: 1783 SELRE 1787
            SEL+E
Sbjct: 1258 SELKE 1262



 Score = 32.0 bits (71), Expect = 7.4
 Identities = 63/275 (22%), Positives = 98/275 (35%), Gaps = 29/275 (10%)

Query: 1582 QEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQN 1641
            QEKVAT    L          E++ G      Q   +T   + +EL E +   E L+A  
Sbjct: 88   QEKVATFRLMLLEKDVNPGGKEETPG------QRPAVTETHQLAELNEKKN--ERLRAAF 139

Query: 1642 SAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNW 1701
              + + + G+   P    ++ +   Q + E     +     SS  S      KKKKKK+ 
Sbjct: 140  GISDSYVDGSSFDPQRRAREAK---QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKD- 195

Query: 1702 VNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNAGDCGSASMKPS 1761
               R SE  S  ++   +KKS+K     S+ E         +PK    + D      K S
Sbjct: 196  -RGRRSESSSPRRE---RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKD---KKRKRS 248

Query: 1762 QSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIE 1821
            +S +   +   A         S         +D       SA           R  +   
Sbjct: 249  RSTTPAPKSRRAHRSTSADSASS--------SDTSRSRSRSAAAKTHTTALAGRSPSPAS 300

Query: 1822 ILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSS 1856
              + E D   +E G T+  T+ PS   ++T   SS
Sbjct: 301  GRRGEGDAPFSEPGTTS--TQRPSSPETATKQPSS 333


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 116/488 (23%), Positives = 186/488 (38%), Gaps = 45/488 (9%)

Query: 821  MSDGDIL---GKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSR--DIIQRGVHDVTV 875
            M  G++L   G  L  +   +   T    N  +  ++    TAT+    +   GV   T+
Sbjct: 3    MQKGNVLLMFGLLLHLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATI 62

Query: 876  DADSWDD---SSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRS 932
               S      S   +S    T   IST   +  S+VSS  +I   S  +T   T S   +
Sbjct: 63   SGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESST---TSSGAST 119

Query: 933  TTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRG 992
             T+    +P        + DS   + G     S+    D      +AS + +   S    
Sbjct: 120  ATNSESSTPSSGASTATNSDSSTTSSG----ASTATNSDSSTTSSEASTATNSESSTTS- 174

Query: 993  MSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKP 1052
             S    A + + +  S+  +     ++  +  G +    S  + + + AG ++  E    
Sbjct: 175  -SGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTT 233

Query: 1053 PSGIGRSTATSSFGFKKPSGVG----SSAMITSSGA---------TITSGSATLGKIPKS 1099
             SG   STAT+S      SG G    S +  TSSGA         T++SG +T+     S
Sbjct: 234  SSGA--STATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESS 291

Query: 1100 AAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSST--SGIPGRGGHRS 1157
                G + A    S   S    +   +  S TT    S    S+SST  SG        S
Sbjct: 292  TPSSGANTATNSESSTTSSGA-NTATNSDSSTTSSGASTATNSESSTTSSGASTATNSES 350

Query: 1158 STSS------IDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES 1211
            ST+S       +S  S+ S+G +T+   E + + SG S+  T   +         ++SES
Sbjct: 351  STTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSES 410

Query: 1212 VSLS---GSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEG 1268
             ++S    +  +S +S ++ GA      GS      S T   L G      SAS   +E 
Sbjct: 411  STVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGT-AALTGMHTTSHSASTAVSEA 469

Query: 1269 VKSSSVMP 1276
                S++P
Sbjct: 470  KPGGSLVP 477



 Score = 75.9 bits (185), Expect = 4e-13
 Identities = 83/382 (21%), Positives = 152/382 (39%), Gaps = 13/382 (3%)

Query: 1037 SPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVG----SSAMITSSGA-TITSGSA 1091
            S   +G S     +   +  G STAT+S      SG      S +  TSSGA T T+  +
Sbjct: 96   STVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDS 155

Query: 1092 TLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPG 1151
            +      S A   +S+     +   + ++   V   +S  T    S      S+ +    
Sbjct: 156  STTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSES 215

Query: 1152 RGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSES 1211
            R     + ++ +S  S+ S+GA+T+   E +   SG  +      +         ++SES
Sbjct: 216  RTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSES 275

Query: 1212 VSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKS 1271
             ++S    +   S S+  + G     +      S       GA     S S+  + G  +
Sbjct: 276  STVSSGISTVTNSESSTPSSGANTATNSESSTTSS------GANTATNSDSSTTSSGAST 329

Query: 1272 SSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLAS 1331
            ++   S +T+     +  S SS T S  S    SGSS+      +   ++  ++S   ++
Sbjct: 330  ATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGAST 389

Query: 1332 SPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTT 1391
            +  S  S TS G   A N  SS+  S  + +  S +S  T+S   +   +   S++   +
Sbjct: 390  ATTSESSTTSSGASTATNSESSTVSSGASTATNSESS--TTSSGANTATNSGSSVTSAGS 447

Query: 1392 GTHEVQSLLMRTGSVRSTLSES 1413
            GT  +  +   + S  + +SE+
Sbjct: 448  GTAALTGMHTTSHSASTAVSEA 469



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 92/429 (21%), Positives = 177/429 (41%), Gaps = 26/429 (6%)

Query: 1061 ATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQ 1120
            AT+S      +  GSS + + +     SGS+       +A I G S      S+  +   
Sbjct: 21   ATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEF 80

Query: 1121 DDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLRE 1180
                  +S+ T  ++ ++      +T+         +ST++ +S  S+ S+GA+T+   +
Sbjct: 81   HTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTAT-NSESSTPSSGASTATNSD 139

Query: 1181 PTKIGSGRSSPVTVNQTDKEKEKVAVSDSE-SVSLSGSPKSSPTSASACGAQGLRQPGSK 1239
             +   SG S+    + +    E    ++SE S + SG+  ++ + +S   ++      S+
Sbjct: 140  SSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSE 199

Query: 1240 YPDIASPTFRRLFGAKAGGKSASAPNTEG----VKSSSVMPSPSTTLARQGSLESPSSGT 1295
                +S       GA     S S   + G      S S   S   + A      +PSSG 
Sbjct: 200  SSTTSS-------GASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGA 252

Query: 1296 G---SMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPA--------SVHSFTSGGL 1344
            G   +  S+   SG+ +   ++ S +++ + ++++S +S+P+        S  S TS G 
Sbjct: 253  GTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGA 312

Query: 1345 VWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTG 1404
              A N  SS+  S  + +  S +S  +S  S         + SG +T T+   S    +G
Sbjct: 313  NTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSS-TTSSG 371

Query: 1405 SVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSP 1464
            +  +T SES  +            + +S  A+     E   + S+G    T ++S   S 
Sbjct: 372  TSTATNSESSTVSSGASTATTSESSTTSSGASTATNSE-SSTVSSGASTATNSESSTTSS 430

Query: 1465 SAMSSSAAG 1473
             A +++ +G
Sbjct: 431  GANTATNSG 439



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 86/418 (20%), Positives = 155/418 (37%), Gaps = 36/418 (8%)

Query: 217 TQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSF 276
           T   + ++  + ++T S+   IAT+ +  T   G S    + SS+   GAS       S 
Sbjct: 83  TSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSST 142

Query: 277 NSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKS 336
            S   +   N        S+   ++S+  N              S+  S  AS    S+S
Sbjct: 143 TSSGASTATN-----SDSSTTSSEASTATNSE------------SSTTSSGASTATNSES 185

Query: 337 MNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTA 396
             V  S  ST    + S+T++  + +++      S G  TA + + S         A TA
Sbjct: 186 STVS-SRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSS----GASTA 240

Query: 397 LRPPQP-PSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKN 455
                  PSSG       + + + SG     NS  ++  S  S+   S    P    +  
Sbjct: 241 TNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTA 300

Query: 456 LSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAA 515
            +++ S          N D +   +        +  T  +   T+  +      S TT++
Sbjct: 301 TNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSE-----SSTTSS 355

Query: 516 KKESLIPSSSGIPKPGSKVPTVKQ--TISPGSTASKESEKFRTTKGSPSQSLSKPITMEK 573
              +   S S     G+   T  +  T+S G++ +  SE   T+ G+ + + S+  T+  
Sbjct: 356 GASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSS 415

Query: 574 ASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVA 631
            ++++             + SG+ T T + SS  S G+G   L      SH  +  V+
Sbjct: 416 GASTAT------NSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVS 467


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 295/1360 (21%), Positives = 481/1360 (35%), Gaps = 227/1360 (16%)

Query: 298  GPQSSSGVNGNVQPPSTA--------GQPPASAIPSPSASKPWRSKSMNVKHSATSTMLT 349
            G  SS  V G++ P ++A        GQ PA+   + +      SK+   +   T+ +  
Sbjct: 278  GETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQ 337

Query: 350  VKQSSTATSPTPSS-----DRLKPPVSEGVKTAPSGQKSMLEKFKLVNAR--TALRPPQP 402
            +   +T T  T S+         P  +   +T PSG+ +      + N    T+     P
Sbjct: 338  INTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMP 397

Query: 403  PSSGPSDGGKDDDAFSESGEMEGFNSGLNS-GGSTNSSPKVSPKLAPPKAGSKNLSNKKS 461
             S   + G  ++ + S SG +    S +++   S   S  +SP   PPK     +S    
Sbjct: 398  TSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPK-----ISTAFH 452

Query: 462  LLQPKEKEEKNRDKNKVCTEKPVKEEKDQV--------------------TEMAPKKTSK 501
              Q +  E   R   +      V +E   +                    TE+    T  
Sbjct: 453  TQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGA 512

Query: 502  IASLIPKGSKTTAAKKESLIPSS-SGIPKPG------SKVPTVKQTISPGSTASKESEKF 554
               L+     T  A     +PS  S I +PG      S   T+ +T   G+      E  
Sbjct: 513  ATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETG 572

Query: 555  RTTKG---SPSQSLSKPITMEKASASSCPAPLEGREAGQ---ASPSGS-----CTMTVAQ 603
             T +    SPS S+++ I   K + S   +P+  R   Q    +PS +      T T  Q
Sbjct: 573  TTGEALLSSPSYSVTQMI---KTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQ 629

Query: 604  SSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALP-SADSCTSPTKMDLSY 662
             S   +  G  Q PQ  Q S   T +V+P          G++   S  S +     D   
Sbjct: 630  ESPAVSQRGHTQAPQTTQESQ-TTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPT 688

Query: 663  SKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVT 722
               A       +G+   T+   T    A    + + T+    GT +S +   T  +S V+
Sbjct: 689  ISAATTFAPAPTGDGHTTQAPTTALQAAP--SSHDATLGPSGGTSLSKTGALTLANSVVS 746

Query: 723  T--------------------------------EVNGRTIPNLTSRPTPMTWRLGQACPR 750
            T                                E +G+T  +  +     T   G A P 
Sbjct: 747  TPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPS 806

Query: 751  LQ--AGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSE-KASS 807
                +G  PS   G   SG +    ++PSR  +TT      +S   +   I +S   ASS
Sbjct: 807  SSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASS 866

Query: 808  DLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQ 867
             +  +    +    + G   G+S  T    S           T +++R+  T  +R    
Sbjct: 867  IVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQ--------ETAAISRMAQTQRTR--TS 916

Query: 868  RGVHDVTVDADSWDDSSSV--------SSGLSDTLDNISTDDLNTTSSVSSYSNITVPSR 919
            RG   +++ + + D  S+V        S+GL  T     T  L+ + S  +++   + + 
Sbjct: 917  RGSDTISLASQATDTFSTVPPTPPSITSTGL--TSPQTETHTLSPSGSGKTFTTALISNA 974

Query: 920  KNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKA 979
              T L       ++T  T      L   +    S G A     T  S +       G   
Sbjct: 975  --TPLPVTYASSASTGHT----TPLHVTDASSVSTGHATPLPVTSPSSV-----STGHTT 1023

Query: 980  SLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPS 1039
             L V+ T S   G        S   A T        TD + AS     PL  +SL     
Sbjct: 1024 PLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSL----- 1078

Query: 1040 DAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKS 1099
             +  S+GD    P       T TSS      +G  +S  +T + +  T  +  L     S
Sbjct: 1079 -SSASTGDTTPLP------VTDTSS----ASTGHATSLPVTDTSSVSTGHTTPLPVTDTS 1127

Query: 1100 AAIGGKSNAGRKTSLDGSQNQDDVVLHV---SSKTTLQYRSLPRPSKSSTS--------- 1147
            +A  G + +   T            LHV   SS +T Q   LP  S SS S         
Sbjct: 1128 SASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPV 1187

Query: 1148 GIPGRGGHRSSTSSIDSNVSSKSAG-----------------ATTSKLREPTKIGSGRSS 1190
              P       +T  + ++ SS S G                 AT+  +  P+   +G ++
Sbjct: 1188 TSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTT 1247

Query: 1191 PVTVNQTDK----EKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASP 1246
            P+ V  T      +   + V+D+ SVS +G     P ++++  + G   P      + SP
Sbjct: 1248 PLPVTDTSSASTGQATSLLVTDTSSVS-TGDTTPLPVTSTSSASTGHVTP----LHVTSP 1302

Query: 1247 TFRRLFGAKAGGKSASAPNT--EGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGL 1304
            +      + + G +   P T      +   MP P T         SPSS +    +   +
Sbjct: 1303 S------SASTGHATPLPVTSLSSASTGDTMPLPVT---------SPSSASTGDTTPLPV 1347

Query: 1305 SGSSSPLFNKPSDL-TTDVISLSHSLASS-PASVHSFTSGGLVWAANMSSSSAGSKD--T 1360
            + +SS      + L  TD  S S   A+  P +  S  S G      ++S S+ S    T
Sbjct: 1348 TDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT 1407

Query: 1361 PSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRST-----LSESMQ 1415
            P   + TS  ++  +  LP++   S+S     T    SL +   S  ST     L  +  
Sbjct: 1408 PLLVTDTSSASTGHATPLPVTDASSVS-----TDHATSLPVTIPSAASTGHTTPLPVTDT 1462

Query: 1416 LDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPL--VSPSAMSSSAAG 1473
               +T     L  T +S  +  +     + S S+     TG+ +PL   SPS+ S+  A 
Sbjct: 1463 SSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSA---STGHVTPLHVTSPSSASTGHAT 1519

Query: 1474 KYHFSNLVSPTNLSQFNLPGPSMMRSNS-----IPAQDSS 1508
                ++L S +      LP  S   +++     +P  D+S
Sbjct: 1520 PLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDAS 1559



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 260/1265 (20%), Positives = 432/1265 (34%), Gaps = 144/1265 (11%)

Query: 201  QRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSS 260
            Q +  A+ PS +       D  +S     A  +NHS I ++   P   P  S+     + 
Sbjct: 588  QMIKTATSPSSSPML----DRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAP 643

Query: 261  SKVQGASNLNRRSQSFNSIDKNKP-PNYANGNEKDSSKGPQSS-------------SGVN 306
               Q +      S   ++     P  ++       S   PQ +             +G  
Sbjct: 644  QTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDG 703

Query: 307  GNVQPPSTAGQPPAS---AIPSPSASKPW-RSKSMNVKHSATSTM--LTVKQSSTATSPT 360
               Q P+TA Q   S   A   PS      ++ ++ + +S  ST      + +S + S +
Sbjct: 704  HTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTS 763

Query: 361  PSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPS-DGGKDDDAFSE 419
            P +        +   T  SGQ    E     +  T+     P SSG S       +  S 
Sbjct: 764  PDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGIST 823

Query: 420  SGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVC 479
            SGE   F+S  +    T  S       +         +   S + P        + +   
Sbjct: 824  SGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEAS--T 881

Query: 480  TEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQ 539
              +P  +        +P++T+ I+ +       T+   +++  +S       +  PT   
Sbjct: 882  AGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPS 941

Query: 540  TISPGSTASKESEKFRTTKGSP--------SQSLSKPITMEKASASSCPAPLEGREAGQA 591
              S G T+ +      +  GS         S +   P+T   ++++    PL   +A   
Sbjct: 942  ITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSV 1001

Query: 592  SPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPF---IYRAHSENEGTALPS 648
            S   +  + V   S  STG+    LP     S  +T  V P     + + S  + T LP 
Sbjct: 1002 STGHATPLPVTSPSSVSTGH-TTPLPVTDTSSE-STGHVTPLPVTSFSSASTGDSTPLPV 1059

Query: 649  ADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQI 708
             D+ ++ T        T+   L   S  D       T   + D         +SL  T  
Sbjct: 1060 TDTSSASTGHVTPLPVTS---LSSASTGD------TTPLPVTDTSSASTGHATSLPVTDT 1110

Query: 709  SH-STLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRL--GQACPRLQAGDAPSLGAG--- 762
            S  ST  TT      T+ +  +  + TS P   T  +  G   P L   DA S   G   
Sbjct: 1111 SSVSTGHTT--PLPVTDTSSASTGHATSLPVTDTSSVSTGHTTP-LHVTDASSASTGQAT 1167

Query: 763  -YPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYM 821
              P +  S     D +    T+P    + +  G+ + + +++ +S+    ++ + V    
Sbjct: 1168 PLPVTSLSSVSTGDTTPLPVTSP----SSASTGHATPLLVTDTSSASTGHATPLPVTD-- 1221

Query: 822  SDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDV----TVDA 877
                    S+ TD   S  +T             IP  A++       V D     T  A
Sbjct: 1222 ------ASSVSTDHATSLPVT-------------IPSAASTGHTTPLPVTDTSSASTGQA 1262

Query: 878  DSW--DDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKN----TQLRTDSEKR 931
             S    D+SSVS+G +  L   ST   +T      +  +T PS  +    T L   S   
Sbjct: 1263 TSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLH--VTSPSSASTGHATPLPVTSLSS 1320

Query: 932  STTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSG-------LPEDPEKAGQKASLSVS 984
            ++T +T   P          D+         +VS+G               GQ   L V+
Sbjct: 1321 ASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVT 1380

Query: 985  QTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKS 1044
               S   G +      S   A T        TD + AS     PL         +DA   
Sbjct: 1381 SLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPL-------PVTDASSV 1433

Query: 1045 SGDEGKKPPSGIGRSTATSSFGFKKPSGV-----GSSAMITSSGATITSGSATLGKIPKS 1099
            S D     P  I  + +T   G   P  V      S+   TS   T TS  +T    P  
Sbjct: 1434 STDHATSLPVTIPSAAST---GHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLP 1490

Query: 1100 AAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSST 1159
                  ++ G  T L  +        H    T L   SL   S   T  +P      +ST
Sbjct: 1491 VTSTSSASTGHVTPLHVTSPSSASTGHA---TPLPVTSLSSASTGDTMPLPVTSPSSAST 1547

Query: 1160 SSID----SNVSSKSAGATTS-KLREPTKIGSGRSSPVTVNQTDK----EKEKVAVSDSE 1210
                    ++ SS S G TT   +  P+   +G ++P+ V  T      +   + V+   
Sbjct: 1548 GDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPS 1607

Query: 1211 SVSLSGSPKSSPTSASACGAQGLRQP------GSKYPDIASPTFRRLFGAKAGGKSASAP 1264
            S S +G     P + ++  + G   P       S     A+P       + + G +   P
Sbjct: 1608 SAS-TGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLP 1666

Query: 1265 --NTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDV 1322
              +T    +    P P T L+   + ++       + SA     +  P+ +  S  T D 
Sbjct: 1667 VTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDT 1726

Query: 1323 ISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSH 1382
              L  +  SS ++ H+      +   + SS+S G + TP   + TS  +++ +  LP++ 
Sbjct: 1727 TPLPVTSPSSASTGHA----SPLLVTDASSASTG-QATPLPVTDTSSVSTAHATPLPVTG 1781

Query: 1383 HGSLS 1387
              S S
Sbjct: 1782 LSSAS 1786



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 244/1142 (21%), Positives = 411/1142 (35%), Gaps = 159/1142 (13%)

Query: 299  PQSSSGVNGNVQPPSTAGQPP---ASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSST 355
            P S+S  +    P + A   P   A+++P   AS      S++  H+    +      ST
Sbjct: 1942 PSSASSGHTTPLPVTDASSVPTGHATSLPVTDAS------SVSTGHATPLPVTDASSVST 1995

Query: 356  A-TSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDD 414
               +P P +D           +  +GQ + L    L +A T    P P +   S     D
Sbjct: 1996 GHATPLPVTD---------TSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQD 2046

Query: 415  DAF---SESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEK 471
                  S S    G  + L     +++S   +  L    A S +  +  SLL        
Sbjct: 2047 TPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVT------ 2100

Query: 472  NRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPG 531
              D + V T           + ++   T+ +    P  + T       +  +SS      
Sbjct: 2101 --DASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHA 2158

Query: 532  SKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQA 591
            + +P                    T+  S   + S P+T   ++++    PL   +   A
Sbjct: 2159 TSLPVTD-----------------TSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSA 2201

Query: 592  SPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFI-YRAHSENEGTALPSAD 650
            S   +  + V   S  STG+    L      +    AT  P     + S  + T LP  D
Sbjct: 2202 STGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTD 2261

Query: 651  SCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISH 710
            + +  T    S   T+   L  +S  D  T    T  + A         ++        H
Sbjct: 2262 ASSVSTGHATSLPVTS---LSSVSTGD-TTPLPVTSPSSASTGHATPLHVTDASSASTGH 2317

Query: 711  ST-LETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAG------Y 763
            +T L  T  S+ +T   G T P   + P+  +   G A P L   DA S+  G       
Sbjct: 2318 ATPLPVTSLSSAST---GDTTPLPVTSPSSAS--TGHATP-LHVTDASSVSTGDTTPLPV 2371

Query: 764  PRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSD 823
              S ++   HT P       P+  A+ +  G+ + + +++ +S+    ++ + V G  S 
Sbjct: 2372 TSSSSASSGHTTP------LPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSA 2425

Query: 824  GDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDS 883
                G + R    N    + G           +P T+TS         D T    +  D+
Sbjct: 2426 S--TGDTTRLPVTNVSSASTG-------HATPLPVTSTS----SASTGDTTPLPGT--DT 2470

Query: 884  SSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLR-----TDSEKRSTTDETW 938
            SSVS+G +  L  + TD  + ++  ++   +T PS  +T        TD+   ST D T 
Sbjct: 2471 SSVSTGHTTPL--LVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTT- 2527

Query: 939  DSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGG 998
                    P  +  S          V+S         G   SL V+ T +   G +    
Sbjct: 2528 ------PLPVTNASSLSTRHATSLHVTS---PSSASTGHATSLPVTDTSAASTGHATPLP 2578

Query: 999  APSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGR 1058
              S   A T        TD   AS     PL  +        +  S+GD    P +    
Sbjct: 2579 VTSTSSASTGDTTPLPVTDTYSASTGQATPLPVT------DTSSASTGDTTPLPVT---- 2628

Query: 1059 STATSSFGFKKPSGVGSSAMITSSGAT---ITS-GSATLG-KIPKSAAIGGKSNAGRKTS 1113
             T+++S G   P  V +++ +++  AT   +TS  SA+ G   P         + G  TS
Sbjct: 2629 DTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATS 2688

Query: 1114 LDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAG- 1172
            L         V   SS  T    SLP    SS S      GH +     D+  SS S G 
Sbjct: 2689 LP--------VTDASSVFTGHATSLPVTIPSSAS-----SGHTTPLPVTDA--SSVSTGH 2733

Query: 1173 ATTSKLREPTKIGSGRSSPVTVNQTDK----EKEKVAVSDSESVSLSG-SPKSSPTSASA 1227
            AT+  + + + + +G ++P+ V             + ++   SVS    +P     ++SA
Sbjct: 2734 ATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSA 2793

Query: 1228 CGAQGLRQPGSKYPDIASPTFRRL----FGAKAGGKSASAPNTEGVKSS----SVMPSPS 1279
               Q    P +    +++     L      + + G + S P T+   +S    + +P   
Sbjct: 2794 STGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTD 2853

Query: 1280 TTLARQGS---LESPSSGTGSMGSAGGL----SGSSSPLFNKPSDLTTDVISLSHSLASS 1332
            T+ A  G    L    + + S+G A  L    + S S     P  +T+   + +      
Sbjct: 2854 TSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPL 2913

Query: 1333 PASVHSFTSGGLVWAANMSSSSAGSKD--TPSYQSMTSLHTSSESIDLPLSHHGSLSGLT 1390
            P +  S  S G     +++S S+ S    TP   + TS  ++  +  LP++   SLS ++
Sbjct: 2914 PVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVT---SLSSVS 2970

Query: 1391 TG 1392
            TG
Sbjct: 2971 TG 2972



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 253/1227 (20%), Positives = 444/1227 (36%), Gaps = 179/1227 (14%)

Query: 213  SQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLNRR 272
            S+A+T    Q   +  +++ S H+ + T+         PS V               N  
Sbjct: 86   SKAQTDTLTQMMTSTLFSSPSVHNVMETAPPDEMTTSFPSSVT--------------NTL 131

Query: 273  SQSFNSIDKNKPPNYANGN-EKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPS------ 325
              +  +I      +   GN E+ S+ G +SS+ V   V    TAGQ   S   S      
Sbjct: 132  MMTSKTITMTTSTDSTLGNTEETSTAGTESSTPVTSAVS--ITAGQEGQSRTTSWRTSIQ 189

Query: 326  ---PSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQK 382
                S+   W   +   + S TST LT + +ST  S +PS   +   VS+  KT+PSG+ 
Sbjct: 190  DTSASSQNHWTRSTQTTRESQTST-LTHRTTST-PSFSPSVHNVTGTVSQ--KTSPSGET 245

Query: 383  SMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKV 442
            +      + N  T++   +  +   S G                 S L + G T+S P V
Sbjct: 246  ATSSLCSVTN--TSMMTSEKITVTTSTG-----------------STLGNPGETSSVP-V 285

Query: 443  SPKLAPPKA---------GSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTE 493
            +  L P  +         G    +  ++  Q      KN     V T +    + + +  
Sbjct: 286  TGSLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTR--VSQINTLNT 343

Query: 494  MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTV--------KQTISPGS 545
            + P  TS + S  P G   +    +   PS        S V           +   S  S
Sbjct: 344  LTPVTTSTVLS-SPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDS 402

Query: 546  TASKESEKFRTTKGSPSQSLSKPITM-------EKASASSCPAPLEGREAGQASPSGSCT 598
            T     E   +  G+ S   SK  T+          S SS P  +      Q S     T
Sbjct: 403  TLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETT 462

Query: 599  MTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKM 658
                + S  S G     + Q+    H  T   + F  + H+    T LPS  S  + T++
Sbjct: 463  GRPHERSSFSPG-----VSQEIFTLHETTTWPSSFSSKGHTTWSQTELPST-STGAATRL 516

Query: 659  DLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFD 718
                  T        +G  P     R    ++ + +  E T  S   T +  +T      
Sbjct: 517  VTGNPSTG------TAGTIP-----RVPSKVSAIGEPGEPTTYSSHSTTLPKTT--GAGA 563

Query: 719  STVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPS- 777
             T  T+  G T   L S P+    ++      ++   +PS      R  TS+ I T PS 
Sbjct: 564  QTQWTQETGTTGEALLSSPSYSVTQM------IKTATSPSSSPMLDRH-TSQQITTAPST 616

Query: 778  -----RFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLR 832
                     T+P    AVS+ G+      ++++ +   +S   D     +     G S  
Sbjct: 617  NHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTP----GSSFT 672

Query: 833  TDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSD 892
                +   +        + +    P         Q     +     S D +   S G S 
Sbjct: 673  ASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTS- 731

Query: 893  TLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFD 952
                     L+ T ++ + +N  V +    + +  S   ST+ +T  +     + E    
Sbjct: 732  ---------LSKTGAL-TLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAEST-- 779

Query: 953  SHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKT 1012
               +A G+ +T       +P  +G + + + + T S         GA     +G+  + T
Sbjct: 780  ---EASGQTQT------SEPASSGSRTTSAGTATPS-------SSGASGTTPSGSEGIST 823

Query: 1013 PGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSG 1072
             G+T    ++     P + S   +S ++   +S   G  P S  G +++     F     
Sbjct: 824  SGETTRFSSN-----PSRDSHTTQSTTELLSASASHGAIPVS-TGMASSIVPGTFHPTLS 877

Query: 1073 VGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTT 1132
              S+A   +  ++ TS SA+     ++AAI   +   R  +  GS       + ++S+ T
Sbjct: 878  EASTAGRPTGQSSPTSPSAS---PQETAAISRMAQTQRTRTSRGSD-----TISLASQAT 929

Query: 1133 LQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPV 1192
              + ++P    S TS   G    ++ T ++  + S K+   TT+ +   T +    +S  
Sbjct: 930  DTFSTVPPTPPSITS--TGLTSPQTETHTLSPSGSGKT--FTTALISNATPLPVTYASSA 985

Query: 1193 TVNQTDKEKEKVAVSDSESVSLSGS---PKSSPTSASACGAQGL--RQPGSKYPDIASPT 1247
            +   T      + V+D+ SVS   +   P +SP+S S      L      S+     +P 
Sbjct: 986  STGHT----TPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPL 1041

Query: 1248 FRRLFGAKAGGKSASAP--NTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLS 1305
                F + + G S   P  +T    +  V P P T+L+   + ++         SA    
Sbjct: 1042 PVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGH 1101

Query: 1306 GSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQS 1365
             +S P+ +  S  T     L  +  SS ++ H+ +    +   + SS S G   TP + +
Sbjct: 1102 ATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATS----LPVTDTSSVSTG-HTTPLHVT 1156

Query: 1366 MTSLHTSSESIDLPLSHHGSLSGLTTG 1392
              S  ++ ++  LP++   SLS ++TG
Sbjct: 1157 DASSASTGQATPLPVT---SLSSVSTG 1180



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 272/1271 (21%), Positives = 462/1271 (36%), Gaps = 175/1271 (13%)

Query: 251  PSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGP--QSSSGVNGN 308
            P  +P+A S+         +  S S          + ++ +  D++  P   +SS   G+
Sbjct: 1234 PVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGH 1293

Query: 309  VQP-----PSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSS 363
            V P     PS+A    A+ +P  S S      +M +  ++ S+      S+  T+P P +
Sbjct: 1294 VTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSA-----STGDTTPLPVT 1348

Query: 364  DRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAF---SES 420
            D           +  +G  + L      +A T    P P +S  S    D       S S
Sbjct: 1349 D---------ASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPS 1399

Query: 421  GEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCT 480
                G  + L    ++++S   +  L    A S +  +  SL               +  
Sbjct: 1400 SASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPV 1459

Query: 481  EKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQT 540
                     Q T +    TS +++       TT     S   +S+G   P          
Sbjct: 1460 TDTSSASTGQATSLLVTDTSSVST-----GDTTPLPVTSTSSASTGHVTP-------LHV 1507

Query: 541  ISPGSTASKESEKFRTTK---GSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSC 597
             SP S ++  +     T     S   ++  P+T   ++++    PL   +A   S   + 
Sbjct: 1508 TSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTT 1567

Query: 598  TMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEG--TALPSADSCTSP 655
             + V   S  STG+    LP     S     T    +    S + G  T LP  D+ ++ 
Sbjct: 1568 PLPVTSPSSASTGH-TTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSAS 1626

Query: 656  TKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHST-LE 714
            T        T    L         T    T  + A         ++S       H+T L 
Sbjct: 1627 TGDTTPLPVTNASSL----STGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLP 1682

Query: 715  TTFDSTVTTEVNGR-TIPNLTSRPTPMTWRLGQACP-------RLQAGDAPSLGAGYPRS 766
             T  S+ TT+   R  + +++S  T      GQA P        +  GD   L    P S
Sbjct: 1683 VTGLSSATTDDTTRLPVTDVSSAST------GQATPLPVTSLSSVSTGDTTPLPVTSPSS 1736

Query: 767  GTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDI 826
             ++   H  P        +  A+ +  G  + + +++ +S     ++ + V G  S    
Sbjct: 1737 ASTG--HASP------LLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTD 1788

Query: 827  LGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSV 886
                L   D++S   T   + L   S    P +A++ D     V D +        S+  
Sbjct: 1789 DTTRLPVTDVSSA-STGQAIPLPVTS----PSSASTGDTTPLPVTDAS------SASTGD 1837

Query: 887  SSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKK 946
            ++ L  T+ + ++    T+  V+  S+++      + L TD+   ST D T      L  
Sbjct: 1838 TTSLPVTIPSSASSGHTTSLPVTDASSVST-GHATSLLVTDASSVSTGDTT-----PLPV 1891

Query: 947  PEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAG 1006
             + +  S GD      T +S +       G   SL V+   S   G +      S   A 
Sbjct: 1892 TDTNSASTGDTTPLHVTDASSV-----STGHATSLPVTSLSSASTGDTTPLPVTSPSSA- 1945

Query: 1007 TSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFG 1066
            +S   TP    DA +   G A    +SL  + +    SS   G   P  +  +++ S+ G
Sbjct: 1946 SSGHTTPLPVTDASSVPTGHA----TSLPVTDA----SSVSTGHATPLPVTDASSVST-G 1996

Query: 1067 FKKPSGVGSSAMITSSGAT---ITS-GSATLG-KIPKSAAIGGKSNAGRKTSLDGSQNQD 1121
               P  V  ++ +++  AT   +TS  SA+ G   P        ++ G+ T L       
Sbjct: 1997 HATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLP------ 2050

Query: 1122 DVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKL-RE 1180
              V  +SS +T     LP  S SS S      GH  +T  + ++ SS S G  TS L  +
Sbjct: 2051 --VTSLSSVSTGDTTPLPVTSPSSAS-----TGH--ATPLLVTDASSVSTGHATSLLVTD 2101

Query: 1181 PTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKY 1240
             + + +G ++ + V          ++S  ++  L   P +SP+SAS          G   
Sbjct: 2102 ASSVSTGHATALHVTDAS------SLSTGDTTPL---PVTSPSSAST---------GDTT 2143

Query: 1241 PDIASPTFRRLFGAKAGGKSASAPNTEGVKSS----SVMPSPSTTLARQGS------LES 1290
            P   + T      + + G + S P T+   +S    + +P   T+ A  G        ++
Sbjct: 2144 PLPVTDT-----SSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDT 2198

Query: 1291 PSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGL-----V 1345
             S+ TG        S SS+   +    L TD  S S   A +P  V S +S        +
Sbjct: 2199 SSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQA-TPLPVTSLSSASTGDTTPL 2257

Query: 1346 WAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLS-GLTTGTHEVQSLLMRTG 1404
               + SS S G   +    S++S+ T  ++  LP++   S S G  T  H   +    TG
Sbjct: 2258 PVTDASSVSTGHATSLPVTSLSSVST-GDTTPLPVTSPSSASTGHATPLHVTDASSASTG 2316

Query: 1405 SVR----STLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSP 1460
                   ++LS +   D   LP      +PSS             + S      TG+ +P
Sbjct: 2317 HATPLPVTSLSSASTGDTTPLPVT----SPSSASTGHATPLHVTDASSV----STGDTTP 2368

Query: 1461 LVSPSAMSSSA 1471
            L   S+ S+S+
Sbjct: 2369 LPVTSSSSASS 2379



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 192/878 (21%), Positives = 320/878 (36%), Gaps = 126/878 (14%)

Query: 556  TTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGA-- 613
            T+  S   +   P+T   ++++    PL   +   AS   +  + V  +S  STG+    
Sbjct: 1590 TSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPL 1649

Query: 614  -VQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEE 672
             V  P      H     V      + S    T LP     ++ T                
Sbjct: 1650 HVTSPSSASTGHATPLPVTS--TSSASTGHATPLPVTGLSSATT---------------- 1691

Query: 673  ISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHST-LETTFDSTVTTEVNGRTIP 731
                D  TR   T  + A   Q     ++SL       +T L  T  S+ +T   G   P
Sbjct: 1692 ----DDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSAST---GHASP 1744

Query: 732  NLTSRPTPMTWRLGQACPRLQAGDAPSLGAGY----PRSGTSRFIHTDPSRFMYT----- 782
             L +  +  +   GQA P L   D  S+   +    P +G S     D +R   T     
Sbjct: 1745 LLVTDASSAS--TGQATP-LPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSA 1801

Query: 783  -------TPLRRAAVSRLGNMSQIDMSE--KASSDLDMSSEVDVGGYMSDGDIL------ 827
                    P+   + +  G+ + + +++   AS+    S  V +    S G         
Sbjct: 1802 STGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTD 1861

Query: 828  GKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVS 887
              S+ T    S  +TD   ++ T     +P T T+         D T       D+SSVS
Sbjct: 1862 ASSVSTGHATSLLVTDAS-SVSTGDTTPLPVTDTN----SASTGDTT--PLHVTDASSVS 1914

Query: 888  SGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKP 947
            +G + +L   S    +T  +      +T PS  ++   T       +         L   
Sbjct: 1915 TGHATSLPVTSLSSASTGDTTP--LPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVT 1972

Query: 948  EEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGT 1007
            +    S G A     T +S +       G    L V+ T S   G +      S   A T
Sbjct: 1973 DASSVSTGHATPLPVTDASSV-----STGHATPLPVTDTSSVSTGQATPLPVTSLSSAST 2027

Query: 1008 SALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGF 1067
                    TD + AS     PL  +SL      +  S+GD    P +    S +++S G 
Sbjct: 2028 GDTTPLPVTDTSSASTGQDTPLPVTSL------SSVSTGDTTPLPVT----SPSSASTGH 2077

Query: 1068 KKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIG-GKSNAGRKTSLDGSQNQDDVVLH 1126
              P       ++ +  +++++G AT   +  ++++  G + A   T        D   L 
Sbjct: 2078 ATP-------LLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLP 2130

Query: 1127 V---SSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTK 1183
            V   SS +T     LP    SS S      GH +S    D++ S+ +  AT+  + + + 
Sbjct: 2131 VTSPSSASTGDTTPLPVTDTSSVS-----TGHATSLPVTDTS-SASTGHATSLPVTDTSS 2184

Query: 1184 IGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGL--RQPGSKYP 1241
              +G ++P+ V  T         S + +   +  P +SP+SAS   A  L      S   
Sbjct: 2185 ASTGHATPLPVTDT---------SSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSAST 2235

Query: 1242 DIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGS---- 1297
              A+P       + + G +   P T+   +SSV    +T+L    SL S S+G  +    
Sbjct: 2236 GQATPLPVTSLSSASTGDTTPLPVTD---ASSVSTGHATSLP-VTSLSSVSTGDTTPLPV 2291

Query: 1298 MGSAGGLSGSSSPLFNKPSDLTTDVISLS--HSLASSPASVHSFTSGGLVWAANMSSSSA 1355
               +   +G ++PL        TD  S S  H+      S+ S ++G        S SSA
Sbjct: 2292 TSPSSASTGHATPLH------VTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSA 2345

Query: 1356 GS-KDTPSYQSMTSLHTSSESIDLPLSHHGSL-SGLTT 1391
             +   TP + +  S  ++ ++  LP++   S  SG TT
Sbjct: 2346 STGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTT 2383



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 293/1415 (20%), Positives = 486/1415 (34%), Gaps = 210/1415 (14%)

Query: 203  VTHASPPSEASQAKTQQDMQSSLAARYATQ---SNHSGIATSQKKPTRLPGPSRVPAAGS 259
            VT AS  S            SS++  +AT    ++ S ++T    P  +  PS   + G 
Sbjct: 2083 VTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSA-STGD 2141

Query: 260  SSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQP-------P 312
            ++ +      +  +    S+      + + G+   S     +SS   G+  P        
Sbjct: 2142 TTPLPVTDTSSVSTGHATSLPVTDTSSASTGHAT-SLPVTDTSSASTGHATPLPVTDTSS 2200

Query: 313  STAGQPPASAIPSPSASKPWRSKSMNVKH-SATSTMLTVKQSSTATSPTPSSDRLKPPVS 371
            ++ GQ     + SPS++    +  + V   S+ ST        T+ S   + D    PV+
Sbjct: 2201 ASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVT 2260

Query: 372  EGVKTAPSGQKSMLEKFKLVNARTALRPPQP---PSSGPSDGGKDDDAFSESGEMEGFNS 428
            +   +  +G  + L    L +  T    P P   PSS  +           S    G  +
Sbjct: 2261 DA-SSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHAT 2319

Query: 429  GLN-------SGGSTNSSPKVSPKLAPP-KAGSKNLSNKKSL----LQPKEKEEKNRDKN 476
             L        S G T   P  SP  A    A   ++++  S+      P      +   +
Sbjct: 2320 PLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASS 2379

Query: 477  KVCTEKPVKEEKDQ---------VTEMAPKKTSKIASLIPKGSKTTAAKKESLIP----- 522
               T  PV +             VT+ +   T     L   G  + +    + +P     
Sbjct: 2380 GHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVS 2439

Query: 523  -SSSGIPKP-----GSKVPTVKQTISPGSTASKESEKFRT-------TKGSPSQSLSKPI 569
             +S+G   P      S   T   T  PG+  S  S    T       +  S   +   P+
Sbjct: 2440 SASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPV 2499

Query: 570  TMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGA---VQLPQQQQHSHPN 626
            T   ++++    PL   +   AS   +  + V  +S  ST +     V  P      H  
Sbjct: 2500 TSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHAT 2559

Query: 627  TATVAPFIYRAHSENEGTALPSADSC------TSPTKMDLSYSKTAKQCL-----EEISG 675
            +  V      A S    T LP   +       T+P  +  +YS +  Q       +  S 
Sbjct: 2560 SLPVTDT--SAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSA 2617

Query: 676  EDPETRRMR-TVKNIADLRQNLEETMSSLRGTQISHST-LETTFDSTVTTEVNGRTIPNL 733
               +T  +  T  + A         +++       H+T L  T  S+ +T   G T P  
Sbjct: 2618 STGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSAST---GHTTPLP 2674

Query: 734  TSRPTPMTWRLGQACPRLQA-----GDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRA 788
             +  + ++     + P   A     G A SL    P S +S   HT P       P+  A
Sbjct: 2675 VTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSG--HTTP------LPVTDA 2726

Query: 789  AVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGL-- 846
            +    G+ + + +++ +S     ++ + V    S             +++G+ T   L  
Sbjct: 2727 SSVSTGHATSLPVTDASSVSTGHATPLPVTDASS-------------VSTGHATPLPLTS 2773

Query: 847  --NLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNT 904
              ++ T     +P T TS     +               SSVS+G  DT     TD  + 
Sbjct: 2774 LSSVSTGDTTPLPVTDTSSASTGQATPLPVTSL------SSVSTG--DTTPLPVTDTSSA 2825

Query: 905  TSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTV 964
            ++  ++   +T  S  +T   T      T+  +      L   +    S G A     T 
Sbjct: 2826 STGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTD 2885

Query: 965  SSGLPE---------DPEKA--GQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTP 1013
            +S +            P  A  G    L V+ T S   G +      S   A T      
Sbjct: 2886 TSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPL 2945

Query: 1014 GKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKP--- 1070
              TD + AS     PL  +SL      +  S+GD    P +    S +++S G   P   
Sbjct: 2946 PVTDTSSASTGHATPLPVTSL------SSVSTGDTTPLPVT----SPSSASTGHTTPLPV 2995

Query: 1071 -------SGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDV 1123
                   +G  ++  +TS+ +  T  +  L     S+A  G++     TSL      D  
Sbjct: 2996 TDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTT 3055

Query: 1124 VLHVSS------------------------KTTLQYRSLPRPSKSSTSGIPGRGGHRSST 1159
             L V+S                         T L   SL   S   T+ +P      +ST
Sbjct: 3056 PLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSAST 3115

Query: 1160 SSIDS----NVSSKSAGATTSKLREPTK---IGSGRSSPVTVNQTDK--EKEKVAVSDSE 1210
                S    + SS S G TTS     T     G   S PVT   +    +   + V+++ 
Sbjct: 3116 GHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETS 3175

Query: 1211 SVSLSGSPKSSPTSASACGAQGLRQPGSKYP-DIASPTFRRLFGAKAGGKSASAP--NTE 1267
            SVS   +     T AS+         G   P  + SP+      + + G +   P  +T 
Sbjct: 3176 SVSTGHATPLLVTDASSAST------GHATPLHVTSPS------SASTGDTTPVPVTDTS 3223

Query: 1268 GVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSH 1327
             V +    P P T L+   + ++       + SA     +  P+ N  S  T D + L  
Sbjct: 3224 SVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPV 3283

Query: 1328 SLASSPASVH---------SFTSGGLVWAANMSSSSAGS--KDTPSYQSMTSLHTSSESI 1376
            +  SS ++ H         S  S G      ++S+S+ S    TP   + TS  ++ ++ 
Sbjct: 3284 TSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTT 3343

Query: 1377 DLPLSHHGSLS-GLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQA 1435
             LP++   S S G TT  H        TG   STL  +     +T     L  T +S  +
Sbjct: 3344 PLPVTSPSSASTGHTTPLHVTIPSSASTGDT-STLPVTGASSASTGHATPLPVTDTSSVS 3402

Query: 1436 NQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSS 1470
                    + S S+     TG+ +PL    A S+S
Sbjct: 3403 TGHATPLPVTSLSS---VSTGDTTPLPVTDASSAS 3434



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 223/1014 (21%), Positives = 343/1014 (33%), Gaps = 120/1014 (11%)

Query: 205  HASPPSEASQAKTQQ---DMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSS 261
            H + PS AS   T        SS++  +AT    +G++++    T     +R+P    SS
Sbjct: 3202 HVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDT-----TRLPVTDISS 3256

Query: 262  KVQG-ASNLNRRSQSFNSIDKNKP-----PNYANGNEKDSSKGPQSSSGVNGNVQP---- 311
               G A+ L   + S  S     P     P+ A+           +SS   G+  P    
Sbjct: 3257 ASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVT 3316

Query: 312  ----PSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLK 367
                 ST    P     + SAS    +       S+ ST  T     T  S   + D   
Sbjct: 3317 STSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTST 3376

Query: 368  PPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFN 427
             PV+ G  +A +G  + L      +  T    P P +S  S    D      + +    +
Sbjct: 3377 LPVT-GASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVT-DASSAS 3434

Query: 428  SGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEE 487
            +G  +     S   VS     P   +   S       P    + +       T  PV + 
Sbjct: 3435 TGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDT 3494

Query: 488  KDQVTEMA-PKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGST 546
                T  A P   + ++S+    +        S + +    P P      V  T S  + 
Sbjct: 3495 SSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLP------VTDTSSASTG 3548

Query: 547  ASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSG 606
             +       T+  S  Q+   P+T+  +S+S    PL        S      + V   S 
Sbjct: 3549 DTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSS 3608

Query: 607  QSTGNGAVQLPQQQQ------HSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDL 660
             STG+    LP          H+ P   T A  +   H+    T LP  D+ ++ T    
Sbjct: 3609 ASTGH-VTPLPVTSTSSASTGHATPLLVTDASSVSTGHA----TPLPVTDASSAST---- 3659

Query: 661  SYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQN----LEETMSSLRGTQISHST-LET 715
                T    + + S           V +++ +       L  T +S   T   H+T L  
Sbjct: 3660 --GDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSAST--GHATPLPV 3715

Query: 716  TFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAG-DAPSLGAGYPRSGTSRFIHT 774
            T  S+V+T   G T+P   + P+  +   G A P    G  + S G   P   T     T
Sbjct: 3716 TIPSSVST---GDTMPLPVTSPSSAS--TGHATPLPVTGLSSASTGDTTPLPVTD----T 3766

Query: 775  DPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILG-KSLRT 833
              +   + TPL    V+   + S  D +    +D+  +S     G+ +   +    S  T
Sbjct: 3767 SSASTRHATPL---PVTDTSSASTDDTTRLPVTDVSSAST----GHATPLPVTSTSSAST 3819

Query: 834  DDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDT 893
             D     +TD   ++ T     +P   TSR     G H   +      D+SSVS+G +  
Sbjct: 3820 GDTTPLPVTDTS-SVSTGHATSLP--VTSRSSASTG-HATPLPVT---DTSSVSTGHATP 3872

Query: 894  LDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDS 953
            L   ST  ++T  +      +T PS  +T   T     ST+  +      L        S
Sbjct: 3873 LPVTSTSSVSTGHATPL--PVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLS 3930

Query: 954  HGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTP 1013
             G A     T  S         G  ++L V+   S   G +      S     T      
Sbjct: 3931 TGHATPLHVTSPSSASR-----GDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPL 3985

Query: 1014 GKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKP---PSGIGRSTATS------- 1063
              TD + AS     PL  +SL      +  S+GD    P   PS       TS       
Sbjct: 3986 PVTDTSSASTGQATPLPVTSL------SSVSTGDTTPLPVTIPSSASSGHTTSLPVTDAS 4039

Query: 1064 --SFGFKKPSGVGSSAM----------ITSSGATITSGSATLGKIPKSAAIGGKSNAGRK 1111
              S G   P  V S++           +T + +  T  +  L     S+A  G +     
Sbjct: 4040 SVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPV 4099

Query: 1112 TSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSG-----IPGRGGHRSSTS 1160
            TSL          L VSS T+    S   P K  T G     +   GG R++TS
Sbjct: 4100 TSLSSVSTGHATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATS 4153



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 258/1276 (20%), Positives = 444/1276 (34%), Gaps = 191/1276 (14%)

Query: 203  VTHASPPSEASQAKTQQDMQSSLAARYATQ---SNHSGIATSQKKPTRLPGPSR------ 253
            VT  S  S            SS +  +AT    +N S ++T    P  +  PS       
Sbjct: 2611 VTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHT 2670

Query: 254  --VPAAGSSSKVQGASN---LNRRSQSFNSIDKNKP---PNYANGNEKDSSKGPQSSSGV 305
              +P   +SS   G +    +   S  F     + P   P+ A+           +SS  
Sbjct: 2671 TPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVS 2730

Query: 306  NGN-----VQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTA-TSP 359
             G+     V   S+     A+ +P   AS      S++  H+    + ++   ST  T+P
Sbjct: 2731 TGHATSLPVTDASSVSTGHATPLPVTDAS------SVSTGHATPLPLTSLSSVSTGDTTP 2784

Query: 360  TPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQP---PSSGPSDGGKDDDA 416
             P +D           +A +GQ + L    L +  T    P P    SS  +        
Sbjct: 2785 LPVTD---------TSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPV 2835

Query: 417  FSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKN 476
               S    G  + L    ++++S   +  L      S ++ +  SL              
Sbjct: 2836 TDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHAT 2895

Query: 477  KVCTEKPVKEEKDQVTEMAPKKTSKIAS--------LIPKGSKTTAAKKESLIPSSSG-- 526
             +    P        T +    TS  ++          P  + T  A    +  +SS   
Sbjct: 2896 PLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSAST 2955

Query: 527  ---IPKPGSKVPTVKQ-------TISPGSTASKESEKFR---TTKGSPSQSLSKPITMEK 573
                P P + + +V           SP S ++  +       T+  S  Q+ + P+T   
Sbjct: 2956 GHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTS 3015

Query: 574  ASASSCPAPL-----EGREAGQASP----------SGSCT-MTVAQSSGQSTGNGAVQLP 617
            ++++    PL          GQA+P          +G  T + V   S  STG+    L 
Sbjct: 3016 SASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLV 3075

Query: 618  QQQQHSHPNTATVAPFI-YRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGE 676
                 +    AT  P     + S  + T LP     TSP+     ++ T+    +  S  
Sbjct: 3076 TDASSASTGQATPLPVTSLSSVSTGDTTPLP----VTSPSSASTGHA-TSLPVTDTSSAS 3130

Query: 677  DPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIPNLTSR 736
              +T  +            + +T S+  G   S    +T+  ST      G T P L + 
Sbjct: 3131 TGDTTSL-----------PVTDTSSAYTGDTTSLPVTDTSSSST------GDTTPLLVTE 3173

Query: 737  PTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVS--RLG 794
             + ++   G A P L   DA S   G                  + TPL   + S    G
Sbjct: 3174 TSSVS--TGHATP-LLVTDASSASTG------------------HATPLHVTSPSSASTG 3212

Query: 795  NMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSL- 853
            + + + +++ +S     ++ + V G  S        L   DI+S           T +  
Sbjct: 3213 DTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSS 3272

Query: 854  ----NRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNT--TSS 907
                + +P   TS      G H   +   S   +SS S+G +  +   ST   +T  T+ 
Sbjct: 3273 VSTGDTMPLPVTSPSSASTG-HATPLPVTS---TSSASTGHATPVPVTSTSSASTGHTTP 3328

Query: 908  VSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSG 967
            +      +  +   T L   S   ++T  T  +P  +  P     S GD      T +S 
Sbjct: 3329 LPVTDTSSASTGDTTPLPVTSPSSASTGHT--TPLHVTIPSS--ASTGDTSTLPVTGASS 3384

Query: 968  LPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKA 1027
                    G    L V+ T S   G +      S     T    TP    DA ++  G+A
Sbjct: 3385 -----ASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGD-TTPLPVTDASSASTGQA 3438

Query: 1028 -PLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATI 1086
             PL  +SL         SS   G   P  +  +++ S       +G  +   +T + +  
Sbjct: 3439 TPLPVTSL---------SSVSTGDTTPLLVTDASSVS-------TGHATPLPVTDTSSAS 3482

Query: 1087 TSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQY-RSLPRPSKSS 1145
            T  +  L     S+A  G++     TSL      D   L V+  +++    + P P   +
Sbjct: 3483 TGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDT 3542

Query: 1146 TSGIPGRGGHRSSTSSIDSNVSSKSAG-ATTSKLREPTKIGSGRSSPVTVNQTDKEK--- 1201
            +S   G      +T    ++ SS S G AT   +  P+   SG ++P+ V  T       
Sbjct: 3543 SSASTG-----DTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGH 3597

Query: 1202 ----EKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAG 1257
                   + S + +  ++  P +S +SAS   A  L    +        T   +  A + 
Sbjct: 3598 VTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSA 3657

Query: 1258 GKSASAP----NTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPL-F 1312
                + P    +T    +    P P T+L+   + ++         SA   +G ++PL  
Sbjct: 3658 STGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSAS--TGHATPLPV 3715

Query: 1313 NKPSDLTT-DVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHT 1371
              PS ++T D + L  +  SS ++ H+      +    +SS+S G   TP   + TS  +
Sbjct: 3716 TIPSSVSTGDTMPLPVTSPSSASTGHATP----LPVTGLSSASTGD-TTPLPVTDTSSAS 3770

Query: 1372 SSESIDLPLSHHGSLS 1387
            +  +  LP++   S S
Sbjct: 3771 TRHATPLPVTDTSSAS 3786



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 136/620 (21%), Positives = 238/620 (38%), Gaps = 112/620 (18%)

Query: 887  SSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKR-STTDETWDSPEELK 945
            S  + + ++    D++ TTS  SS +N  + + K   + T ++     T+ET  +  E  
Sbjct: 104  SPSVHNVMETAPPDEM-TTSFPSSVTNTLMMTSKTITMTTSTDSTLGNTEETSTAGTESS 162

Query: 946  KPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKA 1005
             P                V+S +     + GQ      S+T SWR   S Q  + S Q  
Sbjct: 163  TP----------------VTSAVSITAGQEGQ------SRTTSWRT--SIQDTSASSQNH 198

Query: 1006 GTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSF 1065
             T + +T  ++  +  + +       S+   SPS    +     K  PSG    TATSS 
Sbjct: 199  WTRSTQTTRESQTSTLTHRTT-----STPSFSPSVHNVTGTVSQKTSPSG---ETATSSL 250

Query: 1066 GFKKPSGVGSSAMITSSGATITSGS-ATLGKIPKSAAIG-------------------GK 1105
                   V +++M+TS   T+T+ + +TLG   +++++                    G+
Sbjct: 251  -----CSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQ 305

Query: 1106 SNA--GRKTSLDGS------QNQDDVVLHVSSKTTLQYRS-------LPRPSKSSTSGIP 1150
            S A   R ++ D +      Q Q      VS   TL   +       L  PS  + SG  
Sbjct: 306  SPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTV 365

Query: 1151 GRGGHRSSTSSIDSNVSSKSAGATTSKL-REPTK----IGSGRSSPVTVNQTDKE-KEKV 1204
             +    S  ++  S  S  +    TSK+ R PT     +G+   + ++V+ T      KV
Sbjct: 366  SQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKV 425

Query: 1205 A-VSDSESVSLSGSPKSSPTSASAC-------GAQGLRQPGSKYPDIASPTFRRLFGAKA 1256
            + +  S+++S + SP S P   S         GA+   +P  +    +    + +F    
Sbjct: 426  STIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRPHER-SSFSPGVSQEIFTLHE 484

Query: 1257 GGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPS 1316
                 S+ +++G  + S    PST+      L + +  TG+ G+   +    S +  +P 
Sbjct: 485  TTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAI-GEPG 543

Query: 1317 DLTTDVISLSHSLA-----SSPASVHSFTSGGLVWAANMSSSSAG------SKDTPSYQS 1365
            + TT     SHS        + A        G    A +SS S        +  +PS   
Sbjct: 544  EPTT---YSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSSP 600

Query: 1366 MTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMR--------TGSVRSTLSESMQLD 1417
            M   HTS +    P ++H ++   +T   E  ++  R        T   ++T S S   D
Sbjct: 601  MLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTD 660

Query: 1418 RNTLPKKGLRYTPSSRQANQ 1437
              T+   G  +T S    ++
Sbjct: 661  TKTVTTPGSSFTASGHSPSE 680



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 195/921 (21%), Positives = 317/921 (34%), Gaps = 100/921 (10%)

Query: 522  PSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPA 581
            PSS+      S   T   + S G T S       T+      + S P+T   +S++    
Sbjct: 3110 PSSASTGHATSLPVTDTSSASTGDTTSLPVTD--TSSAYTGDTTSLPVTDTSSSSTGDTT 3167

Query: 582  PLEGREAGQASPSGSCTMTVAQSSGQSTGNGA-VQLPQQQQHSHPNTATVAPFIYRAHSE 640
            PL   E    S   +  + V  +S  STG+   + +      S  +T  V      + S 
Sbjct: 3168 PLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVST 3227

Query: 641  NEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLR--QNLEE 698
               T LP     ++ T        T +  + +IS           V N + +     +  
Sbjct: 3228 GHATPLPVTGLSSAST------GDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPL 3281

Query: 699  TMSSLRGTQISHST-LETTFDSTVTTEVNGRTIP-NLTSRPTPMTWRLGQACPRLQAGDA 756
             ++S       H+T L  T  S+ +T   G   P  +TS  +  T   G   P L   D 
Sbjct: 3282 PVTSPSSASTGHATPLPVTSTSSAST---GHATPVPVTSTSSAST---GHTTP-LPVTDT 3334

Query: 757  PSLGAGYPRSGTSRFIHTDPSRFM--YTTPLRRAAVS--RLGNMSQIDMSEKASSDLDMS 812
             S   G     T+    T PS     +TTPL     S    G+ S + ++  +S+    +
Sbjct: 3335 SSASTG----DTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHA 3390

Query: 813  SEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHD 872
            + + V               T  +++G+ T     L   SL+ +    T+   +      
Sbjct: 3391 TPLPV-------------TDTSSVSTGHATP----LPVTSLSSVSTGDTTPLPVTDASSA 3433

Query: 873  VTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRS 932
             T  A     +S  S    DT   + TD  + ++  ++   +T  S  +T   T      
Sbjct: 3434 STGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTD 3493

Query: 933  TTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRG 992
            T+  +      L        S GD      T +S +       G    L V+ T S   G
Sbjct: 3494 TSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSV-----STGHATPLPVTDTSSASTG 3548

Query: 993  MSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSD-------AGKSS 1045
             + +        A T        T  + +S     PL  +S     +           SS
Sbjct: 3549 DTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSS 3608

Query: 1046 GDEGKKPPSGIGRSTATSSFGFKKP----------SGVGSSAMITSSGATITSGSATLGK 1095
               G   P  +  ST+++S G   P          +G  +   +T + +  T  +  L  
Sbjct: 3609 ASTGHVTPLPV-TSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPV 3667

Query: 1096 IPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHV---SSKTTLQYRSLP--RPSKSSTSGI- 1149
               S+A  G++     TSL      D   L V   SS +T     LP   PS  ST    
Sbjct: 3668 TDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTM 3727

Query: 1150 ------PGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGR-SSPVTVNQTDK--- 1199
                  P       +T    + +SS S G TT      T   S R ++P+ V  T     
Sbjct: 3728 PLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSAST 3787

Query: 1200 -EKEKVAVSDSESVSLSGS---PKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAK 1255
             +  ++ V+D  S S   +   P +S +SAS      L    +        T   +    
Sbjct: 3788 DDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRS 3847

Query: 1256 AGGKSASAP----NTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPL 1311
            +     + P    +T  V +    P P T+ +   +  +      S  SA     +  P+
Sbjct: 3848 SASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPV 3907

Query: 1312 FNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHT 1371
             +  S  T D   L  + ASS ++ H+      +   + SS+S G   T      +S  T
Sbjct: 3908 TSTSSASTGDTTPLPVTNASSLSTGHATP----LHVTSPSSASRGDTSTLPVTDASSAST 3963

Query: 1372 SSESIDLPLSHHGSLSGLTTG 1392
               +  LPL+   SLS ++TG
Sbjct: 3964 -GHATPLPLT---SLSSVSTG 3980



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 102/454 (22%), Positives = 173/454 (38%), Gaps = 71/454 (15%)

Query: 964  VSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQ------KAGTSALKTPGKTD 1017
            V  G  ED    G K +  V+ TGS    +  Q  A S +       A +   +T     
Sbjct: 25   VVPGTTEDTLITGSKTAAPVTSTGSTTATLEGQSTAASSRTSNQDISASSQNHQTKSTET 84

Query: 1018 DAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSA 1077
             +KA       +  S+L  SPS            PP  +     T+SF    PS V ++ 
Sbjct: 85   TSKAQTDTLTQMMTSTLFSSPSVHNVME----TAPPDEM-----TTSF----PSSVTNTL 131

Query: 1078 MITSSGATI-TSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQ-- 1134
            M+TS   T+ TS  +TLG   +++  G +S+    +++  +  Q+      S +T++Q  
Sbjct: 132  MMTSKTITMTTSTDSTLGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDT 191

Query: 1135 --------YRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGS 1186
                     RS     +S TS +  R     +TS+   + S  +   T S+   P+   +
Sbjct: 192  SASSQNHWTRSTQTTRESQTSTLTHR-----TTSTPSFSPSVHNVTGTVSQKTSPSGETA 246

Query: 1187 GRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKY------ 1240
              S     N +    EK+ V+ S     +GS   +P   S+    G   P +        
Sbjct: 247  TSSLCSVTNTSMMTSEKITVTTS-----TGSTLGNPGETSSVPVTGSLMPVTSAALVTFD 301

Query: 1241 PDIASP-TFRRLF--GAKAGGKSASAPNTE--------------GVKSSSVMPSPS---- 1279
            P+  SP TF R       A  K+    + E               V +S+V+ SPS    
Sbjct: 302  PEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSPSGFNP 361

Query: 1280 TTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSF 1339
            +    Q +  S  + T S  S       +S +F  P+   + + +   +  S   ++ + 
Sbjct: 362  SGTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTISAI 421

Query: 1340 TS--GGLVWAANMSSSSAGSKDTPSYQSMTSLHT 1371
            TS    + W+  +S++ + S   P     T+ HT
Sbjct: 422  TSKVSTIWWSDTLSTALSPSSLPPKIS--TAFHT 453



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 79/326 (24%), Positives = 128/326 (39%), Gaps = 57/326 (17%)

Query: 1268 GVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLT----TDVI 1323
            G K+++ + S  +T A   +LE  S+   S  S   +S SS     K ++ T    TD +
Sbjct: 37   GSKTAAPVTSTGSTTA---TLEGQSTAASSRTSNQDISASSQNHQTKSTETTSKAQTDTL 93

Query: 1324 S--LSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTS--LHTSSESIDLP 1379
            +  ++ +L SSP SVH           N+  ++   + T S+ S  +  L  +S++I + 
Sbjct: 94   TQMMTSTLFSSP-SVH-----------NVMETAPPDEMTTSFPSSVTNTLMMTSKTITMT 141

Query: 1380 LSHHGSLSGLT-TGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQE 1438
             S   +L     T T   +S    T +V  T  +  Q  R T  +  ++ T +S Q +  
Sbjct: 142  TSTDSTLGNTEETSTAGTESSTPVTSAVSITAGQEGQ-SRTTSWRTSIQDTSASSQNHWT 200

Query: 1439 EGKEWLRSHSTGGLQDTGNQSPLVSPS--------AMSSSAAGKYHFSNLVSPTNLSQFN 1490
               +  R   T  L      +P  SPS        +  +S +G+   S+L S TN     
Sbjct: 201  RSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTN----- 255

Query: 1491 LPGPSMMRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSME------EV 1544
                SMM S  I    S+          GS         ++  +GS            + 
Sbjct: 256  ---TSMMTSEKITVTTST----------GSTLGNPGETSSVPVTGSLMPVTSAALVTFDP 302

Query: 1545 HGSSLSLVSSTSSLYSTAEEKAHSEQ 1570
             G S +  S TS+  +TA  K H  Q
Sbjct: 303  EGQSPATFSRTSTQDTTAFSKNHQTQ 328


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 318/1428 (22%), Positives = 490/1428 (34%), Gaps = 271/1428 (18%)

Query: 197  VELQQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPA 256
            V  +   +H+ P S  +         SSL     T  +  G   + + P        + A
Sbjct: 253  VSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEA 312

Query: 257  AGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANG-NEKDSSKGPQSSSGVNGNVQPPSTA 315
            +       G+ +    S + ++  + +P  + +  + KD+S  P   SG        ST 
Sbjct: 313  STPVHSSTGSPHTTL-SPASSTTHEGEPTTFQSWPSSKDTSPAP---SGTTSAFVKLSTT 368

Query: 316  GQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVK 375
                 S+ P+   S    + S  + HS  ST +     +TAT+P P+       V E   
Sbjct: 369  YHSSPSSTPTTHFS----ASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTA 424

Query: 376  TAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGS 435
               S   +    F          P    +SG S+         ES    G  +   S   
Sbjct: 425  YHRSPGSTQTMHF----------PESSTTSGHSE---------ESATFHGSTTHTKS--- 462

Query: 436  TNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMA 495
              S+P  +  LA     S   S + +  +         +++K     P            
Sbjct: 463  --STPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSP------------ 508

Query: 496  PKKTSKIASLIPKGSKTTAAKKESL-IPSSSGIPK----PGSKVPTVKQTISPGSTASKE 550
                +   +++P GS  +    +S   P SSG  +    PGS   T K  +S  ST    
Sbjct: 509  ---DAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGS---TTKPGLSEKSTTFYS 562

Query: 551  SEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTG 610
            S +   T   P+   S  ++ E  ++ S P    G     A P GS TM           
Sbjct: 563  SPRSPDTTHLPASMTSSGVSEESTTSHSRP----GSTHTTAFP-GSTTMP---------- 607

Query: 611  NGAVQLPQQQQHSH----PNTATVAPFIYRAHSEN-EGTALPSADSCTSPTKMDLSYSKT 665
                 L Q+   SH    P   T++P    A S   E T   S    T  T   L  + T
Sbjct: 608  ----GLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTL--LPDNTT 661

Query: 666  AKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEV 725
            A   LE        TR   T             T+S    T  +     TTF S  ++  
Sbjct: 662  ASGLLEASMPVHSSTRSPHT-------------TLSPAGST--TRQGESTTFHSWPSSN- 705

Query: 726  NGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPL 785
                     +RP P T                +  A    S TS   H  PS    T   
Sbjct: 706  --------DTRPAPPT----------------TTSAFVEPSTTS---HGSPSSIPTTHIS 738

Query: 786  RRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGG 845
             R+  S L   S    S   S+      E D      +      S  T  I+S   T   
Sbjct: 739  ARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSA 798

Query: 846  LNLYTRSLNRIP-DTATSR---DIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDD 901
            L     S +  P  TAT+         G  + ++ + S  D++      + + +++   +
Sbjct: 799  LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGE 858

Query: 902  LNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKW 961
             +TTS +SS S  T     +T     SE+ +T   +  SP     P              
Sbjct: 859  -STTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPA------------- 904

Query: 962  KTVSSGLPEDPEKAGQKASLSVSQTGSWR-RGMSAQGGAPSRQKAGTSALKTPGKTDDAK 1020
             T SSG+ E+       ++ S S+ GS            P   +  T++  +PG TD   
Sbjct: 905  STTSSGVSEE-------STTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 957

Query: 1021 ASEKGKAPLKGSSLQRSPSDAG--KSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAM 1078
                    L G     SP  +G  +++   G    +G+   + T     + P    S A 
Sbjct: 958  LPASTTTXLVGEP-TTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 1016

Query: 1079 ITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSL 1138
             TSSG  ++  S T    P S            T+  GS                   ++
Sbjct: 1017 TTSSG--VSEESTTSHSRPGST---------HTTAFPGS------------------TTM 1047

Query: 1139 PRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTD 1198
            P  S+ ST+         SS  S D+ +S +S  A +S   E T   SG  S  T    D
Sbjct: 1048 PGVSQESTAS-------HSSPGSTDTTLSPRSTTA-SSLGPESTTFHSGPGSTETTLLPD 1099

Query: 1199 KEKEKVAVSDSESV-SLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAG 1257
                   +  S  V S +GSP+++ + A +   QG            S TF+        
Sbjct: 1100 NTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQG-----------ESTTFQ-------- 1140

Query: 1258 GKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSD 1317
                S P+     S   MP+P TT +    L + S G+ S       S SS+  F +  +
Sbjct: 1141 ----SWPS-----SKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASST-TFGRSEE 1190

Query: 1318 LTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY-QSMTSLHTSSES- 1375
             TT V S   + A++P+   S TS GLV  +    SS GS  T  + +S T+   S ES 
Sbjct: 1191 STT-VHSSPVAPATTPSPARSTTS-GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESR 1248

Query: 1376 --------------------IDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQ 1415
                                ++ P S+H S   + T TH  +S      S  ST S S  
Sbjct: 1249 TSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIAT-THFPESSTTSGRSEESTASHSSP 1307

Query: 1416 LDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSA---A 1472
             D N +      +T S R A      E    + + G  +T   S   +P   + S    +
Sbjct: 1308 -DTNGITPLPAHFTTSGRIA------ESTTFYISPGSMETTLASTATTPGLSAKSTILYS 1360

Query: 1473 GKYHFSNLVSPTNLSQFNLPG-PSMMRS-------NSIPAQDSSFDLYDDSQLCGS---A 1521
                    +SP +++  ++ G P+ + S        + PA  ++  L  +S    S   +
Sbjct: 1361 SSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGS 1420

Query: 1522 TSLEERPRAISHSGSFRDSMEEVH---GSSLSLVSSTSSLYSTAEEKA 1566
            T     P +I+ S SF       H   GS+LS VS  S+      E++
Sbjct: 1421 TETTLSPGSITTS-SFAQEFTTPHSQPGSALSTVSPASTTVPGLSEES 1467



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 277/1282 (21%), Positives = 440/1282 (34%), Gaps = 176/1282 (13%)

Query: 232  QSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGN 291
            ++  SG++         PGP+   A   S+ + G S   + S + +SI  +     + G 
Sbjct: 219  RTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS---QESTASHSIPGSTDTTLSPGT 275

Query: 292  EKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVK 351
               SS GP+S++         S+ G    + +P  + +      S  V  S  S   T+ 
Sbjct: 276  TTPSSLGPESTTF-------HSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLS 328

Query: 352  QSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGG 411
             +S+ T     +     P S+    APSG  S   K       +       PSS P+   
Sbjct: 329  PASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSS-------PSSTPTTH- 380

Query: 412  KDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEK 471
                 FS S    G +         +SSP V+    PP A S    + +      E    
Sbjct: 381  -----FSASSTTLGHSE---ESTPVHSSP-VATATTPPPARSATSGHVE------ESTAY 425

Query: 472  NRDKNKVCT----EKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGI 527
            +R      T    E        + +      T+   S  P    TTAA   +   SS G 
Sbjct: 426  HRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPS---TTAALAHTSYHSSLG- 481

Query: 528  PKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGRE 587
                    T        ST S  SE+ + +  SP    +  +      A S P+ L G  
Sbjct: 482  -------STETTHFRDSSTISGRSEESKASHSSPDAMATTVLP-----AGSTPSVLVGDS 529

Query: 588  AGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALP 647
                  SGS   T    S    G              P+T  +   +  +    E T   
Sbjct: 530  TPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSH 589

Query: 648  SADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQ 707
            S    T  T    S +         + G   E+    +     D   +   T +S  G +
Sbjct: 590  SRPGSTHTTAFPGSTT---------MPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPE 640

Query: 708  IS--HS---TLETTF--DSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLG 760
             +  HS   + ETT   D+T  + +   ++P  +S  +P T  L  A    + G++ +  
Sbjct: 641  YTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHT-TLSPAGSTTRQGESTTFH 699

Query: 761  AG--------YPRSGTSRFI------HTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKAS 806
            +          P + TS F+      H  PS    T    R+  S L   S    S   S
Sbjct: 700  SWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGS 759

Query: 807  SDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIP-DTATSR-- 863
            +      E D      +      S  T  I+S   T   L     S +  P  TAT+   
Sbjct: 760  TQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFP 819

Query: 864  -DIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNT 922
                  G  + ++ + S  D++      + + +++   + +TTS +SS S  T     +T
Sbjct: 820  DSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGE-STTSPISSGSMETTALPGST 878

Query: 923  QLRTDSEKRSTTDETWDSPEELKKP---------EEDFDSHGDAGGKWKTVSSGLPEDPE 973
                 SE+ +T   +  SP     P         EE   SH   G    T ++  P+   
Sbjct: 879  TTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGS---THTTAFPDSTT 935

Query: 974  KAG--QKASLSVSQTGSWRRGMSAQG------GAPSRQKAGTSALKT---PGKTDDAKAS 1022
              G  + ++ S S  GS    +          G P+     + + +T   PG T  A  S
Sbjct: 936  TPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLS 995

Query: 1023 EKGK---APLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSF-GFKKPSGVG--SS 1076
            EK     +  +      SP+    S   E          ST T++F G     GV   S+
Sbjct: 996  EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 1055

Query: 1077 AMITSSGATITS---GSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTL 1133
            A  +S G+T T+    S T   +   +          +T+L         +L  S+    
Sbjct: 1056 ASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHS 1115

Query: 1134 QYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVT 1193
               S PR + S       +G   +  S   S  +  +   TTS   E +    G  S + 
Sbjct: 1116 STGS-PRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIP 1174

Query: 1194 VNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGA--QGLRQPGSKYPDIASPTFRRL 1251
                         S+ ES ++  SP +  T+ S   +   GL +  + Y      T    
Sbjct: 1175 TTHFSASSTTFGRSE-ESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMH 1233

Query: 1252 F--GAKAGGKSASAPNTEGVKSSSVMPSPSTTLA----------RQGSLES---PSSGTG 1296
            F   + A G+S  +  +    + ++   PSTT A            GS+ +   P S T 
Sbjct: 1234 FPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTT 1293

Query: 1297 SMGSAGGLSGSSSPLFNKPSDL-----TTDVISLSHSLASSPASVHSF-----TSGGL-- 1344
            S  S    +  SSP  N  + L     T+  I+ S +   SP S+ +      T+ GL  
Sbjct: 1294 SGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSA 1353

Query: 1345 ---------------VWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGL 1389
                           +  A+M+SSS   + T  Y    S HT++     P S   + SGL
Sbjct: 1354 KSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTA----FPAS--TTTSGL 1407

Query: 1390 TTGTHEVQSLLMRTGSVRSTLS 1411
               + E  +   + GS  +TLS
Sbjct: 1408 ---SQESTTFHSKPGSTETTLS 1426



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 291/1353 (21%), Positives = 465/1353 (34%), Gaps = 192/1353 (14%)

Query: 489  DQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTIS-PGSTA 547
            D  T     + S ++   P  + TT     S      G PK         +T + PGST 
Sbjct: 134  DSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTT 193

Query: 548  ----SKESEKFRTTKGSPSQSLSKPITM-----EKASAS-SCPAPLEGREAGQASPSGSC 597
                S++S  F ++  SP ++LS   T      EK++ S S P P        A P  + 
Sbjct: 194  TAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTI----AFPDSTT 249

Query: 598  TMTVAQSSGQSTGNGAVQLPQQQQHSHPNTA--TVAPFIYRAHSEN-EGTALPSADSCTS 654
               V+Q S  S             HS P +   T++P      S   E T   S+   T 
Sbjct: 250  MPGVSQESTAS-------------HSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTK 296

Query: 655  PTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLE 714
             T+  L  + T    LE  +     T    T             T+S    T  +H    
Sbjct: 297  TTR--LPDNTTTSGLLEASTPVHSSTGSPHT-------------TLSPASST--THEGEP 339

Query: 715  TTFDSTVTTEVNGRTIPNLTSRPTPM--TWRLGQACPRLQAGDAPSLGAGYPRSGTSRFI 772
            TTF S  +++         TS    +  T+    +        A S   G+    T   +
Sbjct: 340  TTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTP--V 397

Query: 773  HTDPSRFMYTTPLRRAAVS-RLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDIL-GKS 830
            H+ P     T P  R+A S  +   +    S  ++  +         G+  +     G +
Sbjct: 398  HSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGST 457

Query: 831  LRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGL 890
              T               Y  SL     T         G  + +  + S  D+ + +   
Sbjct: 458  THTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLP 517

Query: 891  SDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKP--- 947
            + +  ++   D +T S +SS S  T     +T     SEK +T   +  SP+    P   
Sbjct: 518  AGSTPSVLVGD-STPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASM 576

Query: 948  ------EEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPS 1001
                  EE   SH   G    T   G    P  + Q+++ S S  G     +S   G+ +
Sbjct: 577  TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLS-QESTASHSSPGPTDTTLSP--GSTT 633

Query: 1002 RQKAG---TSALKTPGKT------DDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKP 1052
                G   T+    PG T      D+  AS   +A +   S  RSP      +G   ++ 
Sbjct: 634  ASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQG 693

Query: 1053 PSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKT 1112
             S    S  +S+     P    +SA +  S    T+   +   IP +      + +G   
Sbjct: 694  ESTTFHSWPSSNDTRPAPPTT-TSAFVEPS----TTSHGSPSSIPTTHISARSTTSGLV- 747

Query: 1113 SLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAG 1172
                   ++    H S  +T   +++  P   +TSG   RG   +++ S  ++  S +  
Sbjct: 748  -------EESTTYHSSPGST---QTMHFPESDTTSG---RGEESTTSHSSTTHTISSAPS 794

Query: 1173 ATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQG 1232
             T++ + EPT   S   S  T +  D            S + SG  + S  S S+  A G
Sbjct: 795  TTSALVEEPTSYHSSPGSTATTHFPD------------SSTTSGRSEESIASHSSQDATG 842

Query: 1233 LRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPS 1292
                      I  P   R   +   G+S ++P + G   ++ +P  +TT     S  S +
Sbjct: 843  ---------TIVLPA--RSTNSVLLGESTTSPISSGSMETTALPGSTTTPGL--SERSTT 889

Query: 1293 SGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVH------SFTSGGLVW 1346
              +     A  LS +S+       + TT     SH   S P S H      S T+ GL  
Sbjct: 890  FHSSPRSPATTLSPASTTSSGVSEESTT-----SH---SRPGSTHTTAFPDSTTTPGLSR 941

Query: 1347 AANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHG----SLSGLTT--GTHEVQSLL 1400
             +  S SS GS DT    + T+     E    P+S       +L G TT  G  E  +  
Sbjct: 942  HSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTF 1001

Query: 1401 M-------RTGSVRSTLSESMQLDRNTL-PKKGLRYTPSSRQANQEEG--KEWLRSHSTG 1450
                     T S  ST S  +  +  T   + G  +T +   +    G  +E   SHS+ 
Sbjct: 1002 YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 1061

Query: 1451 GLQDTGNQSPLVSPSAMSSSAAG----KYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQD 1506
            G  DT      +SP + ++S+ G     +H     + T L   N     ++ + S P   
Sbjct: 1062 GSTDT-----TLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEA-STPVHS 1115

Query: 1507 SSFDLYDDSQLCGSAT-------------SLEERPRAISHSGSFRDSMEEVHGSSLSLVS 1553
            S+          GS T             S +  P   + + +F +     HGS  S+ +
Sbjct: 1116 STGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPT 1175

Query: 1554 STSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGN-MTGR 1612
            +  S  ST      SE+   +    VA     +   S  S       A+  S G+  T  
Sbjct: 1176 THFSASSTT--FGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMH 1233

Query: 1613 LQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSES 1672
                +  + + E        T   + +  S   A ++   +    P     I   H  E 
Sbjct: 1234 FPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGS---IATTHFPE- 1289

Query: 1673 VSSINSATSHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDI 1732
             SS  S  S  S  S +  D+      N +    +   +S + A        P S     
Sbjct: 1290 -SSTTSGRSEESTASHSSPDT------NGITPLPAHFTTSGRIAESTTFYISPGSM---- 1338

Query: 1733 EELTDSSLPASPKLPHNAGDCGSASMKPSQSAS 1765
             E T +S   +P L   +    S+S  P Q+ S
Sbjct: 1339 -ETTLASTATTPGLSAKSTILYSSSRSPDQTLS 1370


>gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]
          Length = 683

 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 37/106 (34%), Positives = 67/106 (63%)

Query: 77  KEDSKIYTDWANHYLAKSGHKRLIKDLQQDIADGVLLAEIIQIIANEKVEDINGCPRSQS 136
           ++  + Y  W N  L K    + ++DL+QD+ DGV+LA +I+I+A EK+  +   P +Q 
Sbjct: 20  EQQLQAYVAWVNAQLKKRPAVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPGNQQ 79

Query: 137 QMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRY 182
           +M  NV+  L F+A++ + +   SA++I +GNLK+I+ L  +L+ +
Sbjct: 80  EMKNNVEKVLQFVASKKIRMHQTSAKDIVDGNLKSIMRLVLALAAH 125


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 336/1641 (20%), Positives = 573/1641 (34%), Gaps = 264/1641 (16%)

Query: 230  ATQSNHSGIATSQKKPTRLPGPSR-----------VPAAGSSSKVQGASNLNRRSQSFNS 278
            AT+++ + +A+S++  T +PGP             +P+   S  +  +SN+         
Sbjct: 6685 ATETSRTEVASSRR--TSIPGPDHSTESPDISTEVIPSLPISLGITESSNMT-------I 6735

Query: 279  IDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMN 338
            I +  PP               S+S     +  P+T+ +    ++ +        +  MN
Sbjct: 6736 ITRTGPPL-------------GSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMN 6782

Query: 339  VKHSATSTML--TVKQSSTATSPTPSSDRLKPPVS----EGVKTAPSGQKSMLEKFKLVN 392
                  S  +  +++++S ++S  PS     PPVS    + + T PS   S+L    ++ 
Sbjct: 6783 KDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMT 6842

Query: 393  ARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAG 452
              T    P+P +S P +          S   E   +  ++       P  S      +  
Sbjct: 6843 TDTLGTSPEPTTSSPPN--------LSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETT 6894

Query: 453  SKNLSNKKSLLQPKEKEEKN--RDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGS 510
            S    ++ S+L   EK +     D         V       +E    K     SL P   
Sbjct: 6895 SSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLR 6954

Query: 511  KTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTA----SKESEKFRTTKGSPSQSLS 566
            +T+ ++  S    +S +    S+VPT       G+TA    ++ +   RT+   PSQS  
Sbjct: 6955 ETSISQNASFSTDTSIVL---SEVPT-------GTTAEVSRTEVTSSGRTSIPGPSQSTV 7004

Query: 567  KP----ITMEKASASSCPAPLEGRE---AGQASPSGSC---TMTVAQSSGQSTGNGAVQL 616
             P     TM +  AS  P   E  E     Q  PSGS    T+T+  S+ +S       L
Sbjct: 7005 LPEISTRTMTRLFAS--PTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTL 7062

Query: 617  PQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGE 676
             Q+  HS   T      + R   +    + PS +   +P+ +    S  A      IS  
Sbjct: 7063 TQRFPHSEMTT-----LMSRGPGDMSWQSSPSLE---NPSSLPSLLSLPATTSPPPISST 7114

Query: 677  DPETRRMRTVKNIADLRQNLEETMSSLRGT---------QISHST---LETTFDSTVTTE 724
             P T     +   + L  +   T   L  +         ++SH++   L T  D+T T  
Sbjct: 7115 LPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEA 7174

Query: 725  VNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTS----RFIHTDPSRFM 780
            V+  T    ++   P +   G   P     D+ +  A  P   TS      +      F+
Sbjct: 7175 VHPSTNTAASNVEIPSS---GHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFL 7231

Query: 781  YTTPLRRAAVSRLG-NMSQIDMSEKASSDLDMS---SEVDVGGYMSDGDILGKSLRTDDI 836
             T+ +++ ++S L   + +   S + SS ++ S   SEV +G          +  RT+  
Sbjct: 7232 ETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGA-------TTEISRTEVT 7284

Query: 837  NSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDN 896
            +S   +  G    +     +P+ +T+R II+     +  ++      +  S   S +   
Sbjct: 7285 SSSRTSISG----SAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSEST 7340

Query: 897  ISTDDLNTTSSVSSYSNIT--VPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSH 954
             + D   T S V ++S +T  +P  + T L         +    D P     P E     
Sbjct: 7341 FTLDTSTTPSLVITHSTMTQRLPHSEITTL--------VSRGAGDVPRPSSLPVE----- 7387

Query: 955  GDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPG 1014
                              E +   + LS+S   S     S    +     A  ++L TPG
Sbjct: 7388 ------------------ETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPG 7429

Query: 1015 KTD-----DAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRST--ATSSFGF 1067
            +       DA A  +  +P   SS         + + D  K  P      T   TSS G 
Sbjct: 7430 QVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGH 7489

Query: 1068 KKPSGV--------GSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQN 1119
            + PS V         +SAM T S    TS S     +  +  I  +  +   T L  +  
Sbjct: 7490 ESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETST 7549

Query: 1120 QDDVVLHVSSKTTLQYRSLPRPSK-SSTSGI----PGRGGHRSSTSSID------SNVSS 1168
             ++  L   + T L   S    ++ S T  I        G   ST S D        +S+
Sbjct: 7550 SEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDISIGTIPRISA 7609

Query: 1169 KSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVS--DSESVSLSGSPKSSPTSAS 1226
             S    ++K+   T+ G   S   T+  T         S  ++ S+ + G P    T++ 
Sbjct: 7610 SSVLTESAKMTITTQTGPSES---TLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTSM 7666

Query: 1227 ACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQG 1286
              G  G+  P   +    SP    L  +     S    +T  +      P P T+L   G
Sbjct: 7667 GRGPGGVSWPSPPFVKETSPPSSPL--SLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSG 7724

Query: 1287 SLESPSSGTGSMGSA--GGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGL 1344
                P++ T  +G++   G S SSS        LTT      +   +   +VH  T+ G 
Sbjct: 7725 ----PATTTDILGTSTEPGTSSSSSLSTTSHERLTT------YKDTAHTEAVHPSTNTG- 7773

Query: 1345 VWAANMSSSSAGSKD------------TPSYQSMTSLHTSSES-IDLPLSHHGSLSGLTT 1391
                N++++S+G K             T S    TS+ TS+ + ++         S LT 
Sbjct: 7774 --GTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTSTPAFLETRRIQTELASSLTP 7831

Query: 1392 GTHEVQ-SLLMRTGSVRSTLSESMQLDRNT-LPKKGLRYTPSSRQAN------------- 1436
            G  E   S    +G+  ST+   +     T + K+ +   P   Q+              
Sbjct: 7832 GLRESSGSEGTSSGTKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWF 7891

Query: 1437 -----QEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNL 1491
                   E  E   +  T  L  T   +  +  S+ +S        S   S + +S    
Sbjct: 7892 STSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLMR 7951

Query: 1492 PGPSMMRSNSIPAQDS---SFDLYDDSQLCGSATSLEERPRAISHS---------GSFRD 1539
             GP  +   S P  +    SF L         +      P +IS S              
Sbjct: 7952 RGPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAK 8011

Query: 1540 SMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLV 1599
            + + +H SS  + +S ++L ST+ E   + ++     +   S  +  T     S++ H  
Sbjct: 8012 TTDMLHKSSEPVTNSPANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVG-TSSSGHES 8070

Query: 1600 AAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPP 1659
             +F             L  +   K +  + +  T+E      S         +       
Sbjct: 8071 TSF------------VLADSQTSKVTSPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSS 8118

Query: 1660 KDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGK 1719
              L +R+  SSE  S    AT  S++ SG    +  +  +  V S      S F Q    
Sbjct: 8119 LTLGLRKTSSSEGTS---LATEMSTVLSGVPTGATAEVSRTEVTSSSRTSISGFAQL--- 8172

Query: 1720 KKSTKPPSSHSDIEELTDSSL 1740
              +  P +S   I  L  SS+
Sbjct: 8173 --TVSPETSTETITRLPTSSI 8191



 Score = 71.6 bits (174), Expect = 8e-12
 Identities = 356/1748 (20%), Positives = 619/1748 (35%), Gaps = 283/1748 (16%)

Query: 297  KGPQSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTA 356
            +GP    GV+    P      PP+S +  P+ + P         H  ++T L        
Sbjct: 7668 RGP---GGVSWPSPPFVKETSPPSSPLSLPAVTSP---------HPVSTTFLA------H 7709

Query: 357  TSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDD-D 415
              P+P       PV+  + + P+    +L         T+  P    SS  S    +   
Sbjct: 7710 IPPSPL------PVTSLLTSGPATTTDILG--------TSTEPGTSSSSSLSTTSHERLT 7755

Query: 416  AFSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDK 475
             + ++   E  +   N+GG+          +A   +G K+ S+  +            D 
Sbjct: 7756 TYKDTAHTEAVHPSTNTGGTN---------VATTSSGYKSQSSVLA------------DS 7794

Query: 476  NKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVP 535
            + +CT   + +     +  A  +T +I + +   S  T   +ES   S S     G+K+ 
Sbjct: 7795 SPMCTTSTMGDTSVLTSTPAFLETRRIQTEL--ASSLTPGLRES---SGSEGTSSGTKMS 7849

Query: 536  TVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKAS-ASSCPAPLEGREAGQ---A 591
            TV   +  G+T     E   +  G    ++S  I+    S  S+ P   E  E       
Sbjct: 7850 TVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHT 7909

Query: 592  SPSGSCTM-TVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSAD 650
            SP G+ T  T    +  +T          Q  SH   +T    + R   E+     P   
Sbjct: 7910 SPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMST----LMRRGPEDVSWMSPPLL 7965

Query: 651  SCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQ--- 707
              T P+   +S   T       +S   PE+     +   + L   L +T   L  +    
Sbjct: 7966 EKTRPSFSLMSSPATTSP--SPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPV 8023

Query: 708  ------ISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPM-TWRLGQACPRLQAGDAPSLG 760
                  +S +++E    S VTT+   +T P+     T + T   G         D+ +  
Sbjct: 8024 TNSPANLSSTSVEILATSEVTTDTE-KTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSK 8082

Query: 761  AGYPRSGTSRF----IHTDPSRFMYTTPLRRAAVSRLG-NMSQIDMSEKASSDLDMSSEV 815
               P   TS      + T    F  T+ ++    S L   + +   SE  S   +MS+ +
Sbjct: 8083 VTSPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVL 8142

Query: 816  DVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTV 875
                  +  ++     RT+  +S   +  G    T S    P+T+T           +T 
Sbjct: 8143 SGVPTGATAEVS----RTEVTSSSRTSISGFAQLTVS----PETSTETITRLPTSSIMTE 8194

Query: 876  DADSWDDSSSVSSGLSDTLDNISTDDLNTTSS-VSSYSNITVPSRKNTQLRTDSEKRSTT 934
             A+    + +   G   T ++  T D++TT + V ++S +T   R +    T    RS  
Sbjct: 8195 SAEMMIKTQTDPPG--STPESTHTVDISTTPNWVETHSTVT--QRFSHSEMTTLVSRSPG 8250

Query: 935  DETWDSPEELKKPEEDFDSHG-DAGGKWKTVSSGLPEDPEKAGQKASLSVSQTG----SW 989
            D  W S   +++           A      VSS L ED   A    + S+   G    + 
Sbjct: 8251 DMLWPSQSSVEETSSASSLLSLPATTSPSPVSSTLVEDFPSASLPVT-SLLNPGLVITTD 8309

Query: 990  RRGMSAQGGAPSRQKAGTSA------LKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGK 1043
            R G+S + G  S     +++      L+    T+D + S         +S+    S +  
Sbjct: 8310 RMGISREPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSV 8369

Query: 1044 SSGDEGKKPPSGIGR---------STATSSF------GFKKPSGVGSSAMITSSGATITS 1088
             S  E  K  S +G          S +TS F        +  S + S    TSS   I+S
Sbjct: 8370 LSDSETPKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISS 8429

Query: 1089 ---GSATLGKIPKSAAIGGKSN---AGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPS 1142
               GS  L ++P  A          + R TS+ G  +Q  +   +S++   +  + P  +
Sbjct: 8430 ATEGSTVLSEVPSGATTEVSRTEVISSRGTSMSGP-DQFTISPDISTEAITRLSTSPIMT 8488

Query: 1143 KSSTSGIPGRGGHRSSTS----SIDSNVSSKSAGATTSKL-----REPTKIGSGRSSPVT 1193
            +S+ S I    G   +TS    ++D++ ++  +G  ++        E T + S     V 
Sbjct: 8489 ESAESAITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVP 8548

Query: 1194 VNQTDKEKEKVAVSDS----------------ESVSLSGSPKSSPTSASACGAQGLRQPG 1237
                   +E  +VS S                ES+S S  P ++  +        + +  
Sbjct: 8549 WPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTS 8608

Query: 1238 SKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMP------------SPSTTLARQ 1285
            S+ P+ +SP       A+    S    + E +  SS  P            SPS+ LA  
Sbjct: 8609 SE-PETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADL 8667

Query: 1286 GSLE--SPSSGTGSMGSAGGLSGSSSPLFNKP------SDLTTDVISLSHSLASSPASVH 1337
             + +  SP + T ++G+      +S+P F +       S LT+ +  +S S  +S A+  
Sbjct: 8668 VTTKPTSPMATTSTLGNTS--VSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATER 8725

Query: 1338 SFTSGGLVWAANMSSS-----SAGSKDTPS-YQSMTSLHTSSESI---DLPLSHHGSLSG 1388
            S +  G+   A    S     S G   TP   QS  S   S+E+I     PL+  GS   
Sbjct: 8726 SASLSGMPTGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEM 8785

Query: 1389 LTT------GTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKE 1442
              T      G     +  + T S R++   +     +  P  G+  TP SR      G E
Sbjct: 8786 TITPKTGHSGASSQGTFTLDTSS-RASWPGTHSAATHRSPHSGMT-TPMSR------GPE 8837

Query: 1443 WLRSHSTGGLQDTGNQSPLVS------PSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSM 1496
             +   S   ++ T   S LVS      PS + S+ +   H S L   +  +   +    M
Sbjct: 8838 DVSWPSRPSVEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDM 8897

Query: 1497 MRSNSIPAQDS--SFDLYDDSQLCGSATSLEERPRAISH--------------------- 1533
            + ++  P   S  S ++  D  L  S  ++E     +S                      
Sbjct: 8898 LDTSLEPVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYP 8957

Query: 1534 --------------SGSFRDSMEEVHGSSLSL----VSSTSSLYSTAEEKAHSEQIHKLR 1575
                          S + +D +     +S  +    + STS+L  T  E + S++IH   
Sbjct: 8958 GLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTSTLTPTPRETSTSQEIHSAT 9017

Query: 1576 RELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIE 1635
            +      + + + T + S    + ++   S    T      T    +  +  I+   T  
Sbjct: 9018 KPSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTESTEM 9077

Query: 1636 MLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSI-----GSGND 1690
             +  Q  +  A  +G L         L       S + S+ +   SHS +      +  D
Sbjct: 9078 TITTQTGSPGATSRGTLT--------LDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGD 9129

Query: 1691 ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPH-- 1748
                        +S    L S    +     ST P S HS       SSLP +  L    
Sbjct: 9130 VPWLSHPSVEEASSASFSLSSPVMTSSSPVSSTLPDSIHS-------SSLPVTSLLTSGL 9182

Query: 1749 -NAGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLD 1807
                +    S +P  S+      T AE   I ++ ++   ++L++T++     S   H  
Sbjct: 9183 VKTTELLGTSSEPETSSPPNLSSTSAEILAITEVTTD--TEKLEMTNV---VTSGYTH-- 9235

Query: 1808 QIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNNL 1867
                  + + + +      +  +   TG+T   T  P+ S +S   + S+ SL   L   
Sbjct: 9236 --ESPSSVLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMET 9293

Query: 1868 NITEAVSS 1875
            +I+E  SS
Sbjct: 9294 SISEETSS 9301



 Score = 68.2 bits (165), Expect = 9e-11
 Identities = 336/1745 (19%), Positives = 609/1745 (34%), Gaps = 215/1745 (12%)

Query: 252  SRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQP 311
            S +P+A S S     S  +  +++ +  +     N    N         S         P
Sbjct: 5981 SSLPSASSFSGEILTSEASTNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTP 6040

Query: 312  PSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLT-VKQSSTAT--SPTPSSDRLKP 368
            P   G     AI S S   P   ++ NV   +TS +   +K+ STA   + T  S+ +  
Sbjct: 6041 PKVTGSMMEDAIVSTST--PGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFS 6098

Query: 369  PVSEGVKTAPSGQKSML--EKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEM--E 424
             VS    T  S  +       F   +A++   P   P +  S         S    +  +
Sbjct: 6099 SVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQ 6158

Query: 425  GFNSGLNSGGS-TNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKP 483
               SG+ S G  T  +  ++     P A +++  + ++          N D N V    P
Sbjct: 6159 TGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETT------SVMNNDLNDVLKTSP 6212

Query: 484  VK-EEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPG-SKVPTVKQTI 541
               EE + ++  AP   +   S +   + T      S + S + +P P  +K+  +   +
Sbjct: 6213 FSAEEANSLSSQAPLLVTTSPSPV---TSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNL 6269

Query: 542  SPGSTASKESEKFRTTKGSPSQSLSKPITMEKASAS----SCPAPLEGREAGQASP-SGS 596
             P + + +       T  + + + +   ++  A A+    S P       +  + P   +
Sbjct: 6270 EPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDSDPYKAT 6329

Query: 597  CTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSAD------ 650
              + +  +SG S  +    +P+        + T    I+R    +    + S+       
Sbjct: 6330 SAVVITSTSGDSIVS--TSMPRSSAMKKIESETTFSLIFRLRETSTSQKIGSSSDTSTVF 6387

Query: 651  ------SCTSPTKMDL-SYSKTAKQCLEEIS-GEDPETRRMRTVKNIADLRQNLEETMSS 702
                  + T  ++ +L S S+T+ Q  E+ +   D  TR +  +   A L ++ E T+++
Sbjct: 6388 DKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTIAT 6447

Query: 703  LRGTQISHSTLETTFDSTVTTEVNGR-----------TIPNLTSRPTPMTWRLGQACPRL 751
              G   + S    T+D+++TT   G             +  LTSR     +  G + P +
Sbjct: 6448 QTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVP--EYISGTSPPSV 6505

Query: 752  QAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASS---D 808
            +   + S     P   +   + T       ++P+   ++   G +   DM    +S   +
Sbjct: 6506 EKTSSSSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVASLPPN 6565

Query: 809  LDMSSE--VDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDII 866
            L  +S         + D + +  S      N G  T    +  +      P   TS  + 
Sbjct: 6566 LGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVT 6625

Query: 867  QRGVHDVTVDAD----------SWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITV 916
               + D  V               + + S++ GL  T  + S D + +T   +    +T 
Sbjct: 6626 SFNIRDTIVSTSMPGSSEITRIEMESTFSLAHGLKGT--STSQDPIVSTEKSAVLHKLTT 6683

Query: 917  PSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAG 976
             + + ++    S +R++      S E      E   S          +S G+ E      
Sbjct: 6684 GATETSRTEVASSRRTSIPGPDHSTESPDISTEVIPS--------LPISLGITESSNMT- 6734

Query: 977  QKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQR 1036
               + +    GS  +G        +  +AGT ++ T         +   K P   S    
Sbjct: 6735 -IITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILS--WT 6791

Query: 1037 SPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKI 1096
             P    K+S      P   +     +S+    K      S M +    ++   + TLG  
Sbjct: 6792 IPPSIEKTSFSSSLMPSPAMTSPPVSST--LPKTIHTTPSPMTSLLTPSLVMTTDTLGTS 6849

Query: 1097 PKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHR 1156
            P+             +S     +    +L     TT      P  S ++T+      GH 
Sbjct: 6850 PEPTT----------SSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHG 6899

Query: 1157 SSTSSI-DSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKE--------------K 1201
            S +S + DS  +  +A   T+     T + +  S      +  +E               
Sbjct: 6900 SQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSIS 6959

Query: 1202 EKVAVSDSESVSLSGSP-----KSSPTSASACGAQGLRQPGSK--YPDIASPTFRRLFGA 1254
            +  + S   S+ LS  P     + S T  ++ G   +  P      P+I++ T  RLF +
Sbjct: 6960 QNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFAS 7019

Query: 1255 KAGGKSA-----SAPNTEGVKSSSVMPSPSTTLARQGSLES------PSSGTGSMGS--A 1301
                +SA     +     G  S   +   ++T   Q    S      P S   ++ S   
Sbjct: 7020 PTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGP 7079

Query: 1302 GGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVH---SFTSGGLVWAANMSSSSAGSK 1358
            G +S  SSP    PS L + ++SL  + +  P S     + +S  L   + ++SS   + 
Sbjct: 7080 GDMSWQSSPSLENPSSLPS-LLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTT 7138

Query: 1359 DTPSYQSMTSLHTSSESI--DLPLSHHGSLSGLTTG--THEVQSLLMRTGSVRSTLSESM 1414
            D         LHTS E +    P   H S   LTTG  T   +++   T +  S +    
Sbjct: 7139 D--------MLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVE--- 7187

Query: 1415 QLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGK 1474
                  +P  G   +PSS  A+ E  K       T   +DT     + +P  + +S   K
Sbjct: 7188 ------IPSSG-HESPSSALADSETSKATSPMFITSTQEDT--TVAISTPHFLETSRIQK 7238

Query: 1475 YHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISHS 1534
               S+L SP    +    G S+  S++I   ++S  L + S   G+ T +       S  
Sbjct: 7239 ESISSL-SP----KLRETGSSVETSSAI---ETSAVLSEVS--IGATTEISRTEVTSSSR 7288

Query: 1535 GSFRDSMEEVHGSSLSLVSSTSSL--YSTAEEKAHSEQIHKLRRELVASQEKVATLTSQL 1592
             S   S E    + L  +S+T  +  + T+   A S ++    +         +T T   
Sbjct: 7289 TSISGSAE---STMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDT 7345

Query: 1593 SANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQNSAAQAAIQGAL 1652
            S    LV             +   TMT     SE+     T+    A +    +++    
Sbjct: 7346 STTPSLV-------------ITHSTMTQRLPHSEI----TTLVSRGAGDVPRPSSLPVEE 7388

Query: 1653 NGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWVNSRGSELRSS 1712
              P  P   L +    S   VSS   A+SHSS  S     +  + K   V    +E    
Sbjct: 7389 TSP--PSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAE---- 7442

Query: 1713 FKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPH--------NAGDCGSASMKPSQ-- 1762
                   + S+ P  S + +E L  S +    +  H          G   S    PS   
Sbjct: 7443 ------PETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVL 7496

Query: 1763 SASAICECTEAEAEIILQLKSELREKELKLTDIR-LEALSSAHHLDQIREAMNRMQNEIE 1821
              S   + T A   I +   + +      L++ R +++  ++    ++RE     +  + 
Sbjct: 7497 PDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSL- 7555

Query: 1822 ILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNNLNITEAVSSDILLDD 1881
              +A     K  TG T + +R  + S S TS S   QS      ++     +S+  +L +
Sbjct: 7556 ATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDISIGTIPRISASSVLTE 7615

Query: 1882 AGDAT 1886
            +   T
Sbjct: 7616 SAKMT 7620



 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 362/1831 (19%), Positives = 638/1831 (34%), Gaps = 326/1831 (17%)

Query: 291  NEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTV 350
            + ++++   +S+ GV+    P       P+S +P P+ +             + S++ + 
Sbjct: 5899 HSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAIT-------------SHSSLYSA 5945

Query: 351  KQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDG 410
               S+ TS  P +  L            SG++  ++   +++  + L     PS+    G
Sbjct: 5946 VSGSSPTSALPVTSLLT-----------SGRRKTID---MLDTHSELVTSSLPSASSFSG 5991

Query: 411  GKDDDAFSESGEMEGF--NSGLNSGGSTNSSPKVSPKLA---------PPKA-GSKNLSN 458
                   S + E   F  N+   + G+TNS  K+   ++         PPK  GS     
Sbjct: 5992 EILTSEASTNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDA 6051

Query: 459  KKSLLQPKEKEEKNRDKNKVCTEKP-VKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKK 517
              S   P   E KN D++      P +KE+   +   +  +++ + S +   + T  ++ 
Sbjct: 6052 IVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRA 6111

Query: 518  ESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASAS 577
            E               V     T  P S  S +S    + + S S S S P+T+      
Sbjct: 6112 E---------------VTYYDPTFMPASAQSTKSPDI-SPEASSSHSNSPPLTISTHKTI 6155

Query: 578  SCPAPLEGREAGQASPSGSC--------TMTVAQSSGQSTGNGAVQLPQQQQHSHPNTAT 629
                      A Q  PSG          T T+A S+G  +      +  +      N   
Sbjct: 6156 ----------ATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLN 6205

Query: 630  ----VAPFIYRAHSENEGTALPSADSC---TSPTKMDLSYSKTAKQCLEEISGEDPETRR 682
                 +PF     S  E  +L S       TSP+ +  +  + +   L  ++     T  
Sbjct: 6206 DVLKTSPF-----SAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPT-- 6258

Query: 683  MRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDS--------TVTTEVNGRTIPN-- 732
               +  I D+  NLE    S +  + + +T E T D+        T    V   + PN  
Sbjct: 6259 ---LAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEF 6315

Query: 733  -LTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVS 791
              T  P    ++   A           +    PRS   + I ++ + F     LR  + S
Sbjct: 6316 YFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETT-FSLIFRLRETSTS 6374

Query: 792  -RLGNMSQIDM----------SEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGY 840
             ++G+ S              +E + ++L  SS   + G          S R+  + S +
Sbjct: 6375 QKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTF 6434

Query: 841  MTDGGLNLYTRSLNRIPDTATSRDII---------QRGVHDVTVDADSWDDSSSVSSGLS 891
                     T +    P  ATS+  +         Q G H       S  D S+++S + 
Sbjct: 6435 AGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVP 6494

Query: 892  DTLDNISTDDLNTTSSVSSYSN---ITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPE 948
            + +   S   +  TSS SS  +   IT PS   T L  +S   S    T      L K  
Sbjct: 6495 EYISGTSPPSVEKTSSSSSLLSLPAITSPSPVPTTL-PESRPSSPVHLTSLPTSGLVKTT 6553

Query: 949  EDFDS-------HGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPS 1001
            +   S        G    K  T S  + +D EK     +++V+  G+      +    P+
Sbjct: 6554 DMLASVASLPPNLGSTSHKIPTTSEDI-KDTEKMYPSTNIAVTNVGTTTSEKESYSSVPA 6612

Query: 1002 RQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTA 1061
                     + P  T     S   +  +  +S+  S                S I R   
Sbjct: 6613 YS-------EPPKVTSPMVTSFNIRDTIVSTSMPGS----------------SEITRIEM 6649

Query: 1062 TSSFGFKKPSGVGSSAMITSSGATI-TSGSATLGKIPKSAAIGGKSN--AGRKTSLDG-- 1116
             S+F        G     TS    + T  SA L K+   A    ++   + R+TS+ G  
Sbjct: 6650 ESTFSLAH----GLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPD 6705

Query: 1117 -SQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGI----PGRGGHRSSTSSIDSNVSSKSA 1171
             S    D+   V     +   SL     S+ + I    P  G     T ++D+  +S  A
Sbjct: 6706 HSTESPDISTEVIPSLPI---SLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRA 6762

Query: 1172 GATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAV-----SDSESVSLSGSPKSSPTSAS 1226
            G  +   +E        S   TV   D E     +       S S SL  SP  +    S
Sbjct: 6763 GTHSMATQE-----FPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPVS 6817

Query: 1227 ACGAQGLRQPGSKYPDIASPTF---RRLFGAKAGGKSASAPN----------TEGVKSSS 1273
            +   + +    S    + +P+        G      ++S PN          T+   ++ 
Sbjct: 6818 STLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAI 6877

Query: 1274 VMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDV----ISLSHSL 1329
                PST+ A   ++E+ SSG GS  S   L+ S       P D T+ +    +S S S+
Sbjct: 6878 EAMHPSTSTAAT-NVETTSSGHGSQSSV--LADSEKTKATAPMDTTSTMGHTTVSTSMSV 6934

Query: 1330 ASSPA-----SVHSFTSGGLVWAANMSSSSAGSKDTP-------------------SYQS 1365
            +S        S +S T G  +   ++S +++ S DT                    +   
Sbjct: 6935 SSETTKIKRESTYSLTPG--LRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSG 6992

Query: 1366 MTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLM----RTGSVRSTLSESMQLDRNTL 1421
             TS+   S+S  LP     +++ L       +S  M    +TG   ST  +++ LD +T 
Sbjct: 6993 RTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTT 7052

Query: 1422 PKKGLRYTPSSRQANQEEGKEWLRSHSTGGL---QDTGNQSPLVSPSAMSSSAAGKYHFS 1478
              +   ++  +++    E    L S   G +        ++P   PS +S  A       
Sbjct: 7053 KSQAKTHSTLTQRFPHSE-MTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPI 7111

Query: 1479 NLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAISH----- 1533
            +   P  +S   LP  S++ S+ +   D    L+   +L  S+      P  +SH     
Sbjct: 7112 SSTLPVTISSSPLPVTSLLTSSPVTTTDM---LHTSPELVTSS------PPKLSHTSDER 7162

Query: 1534 --SGSFRDSMEEVHGSSLSLVSS----TSSLYSTAEEKAHSEQIHKLRRELVASQEKVAT 1587
              +G    + E VH S+ +  S+    +S   S +   A SE         + S ++  T
Sbjct: 7163 LTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTT 7222

Query: 1588 LTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKES-------ELIELRETIEMLKAQ 1640
            +              ++S+ +++ +L+    + E   +         + +  T E+ + +
Sbjct: 7223 VAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTE 7282

Query: 1641 -NSAAQAAIQGA---------------LNGPDHP----PKDLRIRRQHS-----SESVSS 1675
              S+++ +I G+               +  P  P      ++ I+ Q S     SES  +
Sbjct: 7283 VTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFT 7342

Query: 1676 INSATS---------------HSSI------GSGNDADSKKKKKKNWVNSRGSELRSSFK 1714
            ++++T+               HS I      G+G D            +   S+L  S  
Sbjct: 7343 LDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAG-DVPRPSSLPVEETSPPSSQLSLSAM 7401

Query: 1715 QAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNAGDCGSASMKPSQSASAICECTEAE 1774
             +     ST P SSHS    +T    P   K      +   AS +P  S+      T  E
Sbjct: 7402 ISPSPVSSTLPASSHSSSASVTSLLTPGQVK----TTEVLDASAEPETSSPPSLSSTSVE 7457

Query: 1775 AEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDR-LKAE 1833
                +   SE+     K+      A++         E+ + +  + E  KA +     + 
Sbjct: 7458 ----ILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGTISI 7513

Query: 1834 TGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNNLNITE----AVSSDILLDDAGDATGHK 1889
             G+T+  T  P+ S++    S    SL   L   + +E    A  ++ +L         +
Sbjct: 7514 MGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTE 7573

Query: 1890 DGRSVKIIVSISKGYGRAKDQKSQAYLIGSI 1920
              R+  I  S +   G  +   SQ   IG+I
Sbjct: 7574 VSRTEAISFSRTSMSGPEQSTMSQDISIGTI 7604



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 354/1745 (20%), Positives = 635/1745 (36%), Gaps = 285/1745 (16%)

Query: 199  LQQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKP-TRLPGP--SRVP 255
            L QR  H+   +  S+       QSS      +  N S + +    P T  P P  S +P
Sbjct: 7062 LTQRFPHSEMTTLMSRGPGDMSWQSS-----PSLENPSSLPSLLSLPATTSPPPISSTLP 7116

Query: 256  AAGSSSKVQGASNLNRRSQSFNS-------IDKNKPPNYANGNEKDSSKGPQ-------- 300
               SSS +   S L     +          +  + PP  ++ +++  + G          
Sbjct: 7117 VTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVH 7176

Query: 301  -SSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSM-NVKHSATSTMLTVKQSSTATS 358
             S++    NV+ PS+  + P+SA+     SK      + + +   T  + T     T+  
Sbjct: 7177 PSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRI 7236

Query: 359  PTPSSDRLKPPVSE---GVKTAPSGQKSMLEKFKLVNARTAL-RPPQPPSSGPSDGGKDD 414
               S   L P + E    V+T+ + + S +     + A T + R     SS  S  G  +
Sbjct: 7237 QKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAE 7296

Query: 415  DA-------------------FSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKN 455
                                  +ES EM    +  +  GST+ S         P     +
Sbjct: 7297 STMLPEISTTRKIIKFPTSPILAESSEMT-IKTQTSPPGSTSESTFTLDTSTTPSLVITH 7355

Query: 456  LSNKKSLLQPKEKEEKNRDKNKV--CTEKPVKE---EKDQVTEMAPKKTSKIASLIPKGS 510
             +  + L   +     +R    V   +  PV+E      Q++  A    S ++S +P  S
Sbjct: 7356 STMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASS 7415

Query: 511  KTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKP-- 568
             +++A   SL+                 +T SP S +S   E   T++ +       P  
Sbjct: 7416 HSSSASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFS 7475

Query: 569  ---ITMEKASASSCPAP---LEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQH 622
               +T    S+S   +P   L   E  +A+ S   T+++   +  ST   A+   ++ Q 
Sbjct: 7476 NTAVTKVGTSSSGHESPSSVLPDSETTKAT-SAMGTISIMGDTSVSTLTPALSNTRKIQS 7534

Query: 623  SHPNTATVAPFIYRAHSENEGTALP----------SADSCTSPTKMD-LSYSKTAKQCLE 671
               ++ T      R  S +E T+L           S  + T  ++ + +S+S+T+    E
Sbjct: 7535 EPASSLTTR---LRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPE 7591

Query: 672  EIS-GEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTI 730
            + +  +D     +  +   + L ++ + T+++  G   S STLE+T +      +N  T 
Sbjct: 7592 QSTMSQDISIGTIPRISASSVLTESAKMTITTQTGP--SESTLESTLN------LNTATT 7643

Query: 731  PNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFI-HTDPSRFMYTTPLRRAA 789
            P+     + +     Q  P  +   +   G G     +  F+  T P     ++PL   A
Sbjct: 7644 PSWVETHSIVI----QGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPP----SSPLSLPA 7695

Query: 790  VSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLY 849
            V+    +S   ++    S L ++S +   G  +  DILG S           T    +L 
Sbjct: 7696 VTSPHPVSTTFLAHIPPSPLPVTSLL-TSGPATTTDILGTSTEPG-------TSSSSSLS 7747

Query: 850  TRSLNRI---PDTATSRDI---IQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLN 903
            T S  R+    DTA +  +      G  +V   +  +   SSV   L+D+    +T  + 
Sbjct: 7748 TTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSSGYKSQSSV---LADSSPMCTTSTMG 7804

Query: 904  TTSSVSSYSNITVPSRKNTQ--------LRTDSEKRSTTDETWDSPEELKKP-------- 947
             TS ++S        R  T+        LR  S    T+  T  S    K P        
Sbjct: 7805 DTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATTEIS 7864

Query: 948  EEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGT 1007
            +ED  S    G    T+S   P+   +     S S   T S    M+           GT
Sbjct: 7865 KEDVTS--IPGPAQSTIS---PDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGT 7919

Query: 1008 SALKTPGKTD----DAKASEKGKAPLKGSSLQRSPSDAGKSSGD--EGKKPPSGIGRSTA 1061
            S L T   T      +  S+        + ++R P D    S    E  +P   +  S A
Sbjct: 7920 STLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMSSPA 7979

Query: 1062 TSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQD 1121
            T+S     PS V S+   + S + +   S     + K+  +  KS+     S     +  
Sbjct: 7980 TTS-----PSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTS 8034

Query: 1122 DVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRS--------------STSSIDSNVS 1167
              +L  S  TT   ++ P  +++ T       GH S              S   I S + 
Sbjct: 8035 VEILATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTME 8094

Query: 1168 SKSAGATTSKLREPTKIGSGRSSPVTVN-QTDKEKEKVAVSDSESVSLSGSP-------- 1218
              S   +T    E ++I +  +S +T+  +     E  +++   S  LSG P        
Sbjct: 8095 DTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVS 8154

Query: 1219 KSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSA------------SAPNT 1266
            ++  TS+S     G  Q  +  P+ ++ T  RL  +    +SA            S P +
Sbjct: 8155 RTEVTSSSRTSISGFAQL-TVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPES 8213

Query: 1267 EGVKSSSVMP----SPSTTLARQGSLE-------SPSSGTGSMGSAGGLSGSSSPLFNKP 1315
                  S  P    + ST   R    E       SP        S+   + S+S L + P
Sbjct: 8214 THTVDISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLP 8273

Query: 1316 SDLTTDVIS--LSHSLASSPASVHSFTSGGLVWAANM-------SSSSAGSKDTPSYQSM 1366
            +  +   +S  L     S+   V S  + GLV   +         +SS  +  + S++ +
Sbjct: 8274 ATTSPSPVSSTLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERL 8333

Query: 1367 TSLHTSSESIDLPLSHHGSLSGLTTGT--HEVQSLLM----------------RTGSVRS 1408
            T+L  + ++ D+  S H +++ + T    HE QS ++                  G    
Sbjct: 8334 TTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSV 8393

Query: 1409 TLSES-------MQLDRNTLPKKGLRYTPSS-RQANQEEGKEWLRSHSTGGLQDTGNQSP 1460
            ++S S       +Q++  +    GLR T SS R ++  EG   L    +G   +      
Sbjct: 8394 SISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEV 8453

Query: 1461 LVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGS 1520
            +   S+  +S +G   F+  +SP      ++   ++ R ++ P    S +         S
Sbjct: 8454 I---SSRGTSMSGPDQFT--ISP------DISTEAITRLSTSPIMTESAE---------S 8493

Query: 1521 ATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKA-----HSEQIHKLR 1575
            A ++E      +  G            +L+L +ST++ +S     A     HSE    + 
Sbjct: 8494 AITIETGSPGATSEG------------TLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMS 8541

Query: 1576 R-------ELVASQEKVATLTSQLSANAHLVAAF----EKSLGNMTGRLQSLTMTAEQKE 1624
            R         + S E+ ++++S LS+ A    +F     +S+ +    + +L      K 
Sbjct: 8542 RTPGDVPWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKT 8601

Query: 1625 SELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSAT---S 1681
            ++++      E     N ++ +A    +       KD    + H S +   +N  T    
Sbjct: 8602 TDMLRTSSEPETSSPPNLSSTSA---EILATSEVTKDR--EKIHPSSNTPVVNVGTVIYK 8656

Query: 1682 HSSIGS--GNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSS-HSDIEELTDS 1738
            H S  S   +   +K        ++ G+   S+   AF +   T+P SS  S + E++ S
Sbjct: 8657 HLSPSSVLADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTS 8716

Query: 1739 SLPAS 1743
               +S
Sbjct: 8717 QETSS 8721



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 291/1393 (20%), Positives = 513/1393 (36%), Gaps = 232/1393 (16%)

Query: 280  DKNKPPNYANGNE---------KDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSPSASK 330
            + + PPN ++ +          KD  K   SS+    NV         P+S +     +K
Sbjct: 8612 ETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTK 8671

Query: 331  PWR--SKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKF 388
            P    + +  + +++ ST       +  T PT S       +S   +T+ + ++S     
Sbjct: 8672 PTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSG 8731

Query: 389  KLVNART------ALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGGSTNSSPKV 442
                A T      AL   +  + GP+      +  +E+  +   ++ L + GS   +  +
Sbjct: 8732 MPTGATTKVSRTEALSLGRTSTPGPAQSTISPEISTET--ITRISTPLTTTGSAEMT--I 8787

Query: 443  SPKLAPPKAGSKNL----SNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAP-- 496
            +PK     A S+      ++ ++          +R  +   T    +  +D      P  
Sbjct: 8788 TPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSV 8847

Query: 497  KKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRT 556
            +KTS  +SL+   + T+ +   S  PS S    P  +V ++   +   +T   ++     
Sbjct: 8848 EKTSPPSSLVSLSAVTSPSPLYST-PSESSHSSP-LRVTSLFTPVMMKTTDMLDTSLEPV 8905

Query: 557  TKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQL 616
            T   PS +    IT +++ A+S  A +E  EA Q S + + T     S+ Q   +    L
Sbjct: 8906 TTSPPSMN----ITSDESLATS-KATME-TEAIQLSENTAVTQMGTISARQEFYSSYPGL 8959

Query: 617  PQQQQHSHP--NTATVAPFIYR---AHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLE 671
            P+  + + P   ++T+   +     A SE     + S  + T PT  + S S+      E
Sbjct: 8960 PEPSKVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTSTLT-PTPRETSTSQ------E 9012

Query: 672  EISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIP 731
              S   P T   + + + A +  ++ + MSS RG     ST+     + V T ++   I 
Sbjct: 9013 IHSATKPSTVPYKALTS-ATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIK 9071

Query: 732  NLTSRPTPMTWRLGQ--ACPR--LQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRR 787
              ++  T +T + G   A  R  L    + +  +G   + +  F H+  +  M  TP   
Sbjct: 9072 TESTEMT-ITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTP--- 9127

Query: 788  AAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLN 847
                 +  +S   + E +S+   +SS V                         MT     
Sbjct: 9128 ---GDVPWLSHPSVEEASSASFSLSSPV-------------------------MTSSS-- 9157

Query: 848  LYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSS 907
                     P ++T  D I      VT         S ++SGL  T + + T     TSS
Sbjct: 9158 ---------PVSSTLPDSIHSSSLPVT---------SLLTSGLVKTTELLGTSSEPETSS 9199

Query: 908  VSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSG 967
              + S+ +      T++ TD+EK   T+                            V+SG
Sbjct: 9200 PPNLSSTSAEILAITEVTTDTEKLEMTN---------------------------VVTSG 9232

Query: 968  LPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSAL-KTPGKTDDAKASEKGK 1026
               +   +    S++   T S   G++   G        T+ L  TP  +D ++   K K
Sbjct: 9233 YTHESPSSVLADSVTTKATSS--MGITYPTG-------DTNVLTSTPAFSDTSRIQTKSK 9283

Query: 1027 APLKGSSLQRSPSDAGKSSGDEG---KKPPSG----IGRSTATSSFGFKKPSGVGSSAMI 1079
              L    ++ S S+   S+ ++       P+G    + R+ A SS     P    S+   
Sbjct: 9284 LSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSS 9343

Query: 1080 TSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLP 1139
             +S  TIT  S  L +   +           KT   G+ +Q    L              
Sbjct: 9344 DTSMETITRISTPLTRKEST-----DMAITPKTGPSGATSQGTFTL-------------- 9384

Query: 1140 RPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDK 1199
                SST+  PG   H ++T     +V       TT   R P  +     SP++V +   
Sbjct: 9385 --DSSSTASWPGT--HSATTQRFPQSV------VTTPMSRGPEDV--SWPSPLSVEKNSP 9432

Query: 1200 EKEKVAVSDSESVS-----LSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGA 1254
                V+ S   S S      SGS  SSP   ++     + +               +  A
Sbjct: 9433 PSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATD------------MLDA 9480

Query: 1255 KAGGKSASAPNTEGVKSSSVMPSPSTTLARQ-GSLESPSSGTGSMGSAGGLSGSSSPLFN 1313
                ++ SAPN       S+  S +TT        E+ ++      SA     SSSP F+
Sbjct: 9481 SLEPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFS 9540

Query: 1314 KPSDLTTDVISLSHSLASSPASVHSFTSGGL--VWAANMSSSSAGSKDTPSYQSMT-SLH 1370
            +P+ + + V++ S S+  +  S     S G+  +   +MSS + G ++T + Q +T S  
Sbjct: 9541 EPTKVISPVVT-SSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTE 9599

Query: 1371 TSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTP 1430
            TS+    +P       SG T      + +     S+      +M LD +      L  +P
Sbjct: 9600 TSTVLYKMP-------SGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSP 9652

Query: 1431 SSRQANQ-----EEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYH--FSNLVS- 1482
               ++ +     + G     S  T  L   G     +S    S+ + G  H   +NL+S 
Sbjct: 9653 IMTESAEITITTQTGYSLATSQVTLPL---GTSMTFLS-GTHSTMSQGLSHSEMTNLMSR 9708

Query: 1483 -PTNLS----QFNLPGPSMMRSNSIPAQDS----SFDLYDDSQLCGSATSLEERPRAISH 1533
             P +LS    +F     S     S+P   S    S  L D S       +    P  +  
Sbjct: 9709 GPESLSWTSPRFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKT 9768

Query: 1534 SGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLTSQLS 1593
            +     S E    SS +L S++  + +T+E    +E+IH      VA   KV T +S   
Sbjct: 9769 TEVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVA---KVRTSSSVHE 9825

Query: 1594 ANAHLVAAFEKSL 1606
            +++ ++A  E ++
Sbjct: 9826 SHSSVLADSETTI 9838



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 268/1378 (19%), Positives = 473/1378 (34%), Gaps = 249/1378 (18%)

Query: 308  NVQPPSTAGQPPASAIPSPSASKPWRSKS--MNVKHSATSTMLTVKQSSTATSPTPSSDR 365
            N + P ++ +P ++     S S P  S +  +  K SATST    K +S+ T+ TP    
Sbjct: 702  NTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEI-- 759

Query: 366  LKPPVSEGVKTAPSGQKSMLEKFKLVNARTA---LRPPQPPSSGPSDGGKDDDAFSESGE 422
                     KT PS   ++L    L NA T+   +R    P + PS  G+         E
Sbjct: 760  -------STKTKPS--SAVLSSMTLSNAATSPERVRNATSPLTHPSPSGE---------E 801

Query: 423  MEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEK 482
              G    L++   T  SP + P                                   T  
Sbjct: 802  TAGSVLTLSTSAETTDSPNIHP-----------------------------------TGT 826

Query: 483  PVKEEKDQVTEMAPKKTSKIASLIPKGSKTT---AAKKESLIPSSSGIPKPGSKVPTVKQ 539
               E  +  + ++    S + +     + +T    + +E+   S+  + +P + V  V+ 
Sbjct: 827  LTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRT 886

Query: 540  TISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTM 599
            T++  S  +       T     +Q  S  +  E  + SS             + +GS   
Sbjct: 887  TLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSS---------TSVTNSTGSALP 937

Query: 600  TVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMD 659
             ++  +G +T      + Q  + +  ++A      +   S    T LPSA +  S +   
Sbjct: 938  KISHLTGTAT------MSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATS 991

Query: 660  LS-------YSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHST 712
            LS       ++  A   +E  S  +P T  + T          +  T   +    I+   
Sbjct: 992  LSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGR 1051

Query: 713  L-------------ETTFDSTVTTE------------------VNGRT----------IP 731
            L             ET+ D T+  E                    GRT          + 
Sbjct: 1052 LDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVY 1111

Query: 732  NLTSR--PTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAA 789
            +LTSR    P         P++ A   PS   G  RS     + + PS     TP     
Sbjct: 1112 HLTSREITIPRDGTSSALTPQMTATHPPSPDPGSARSTWLGILSSSPSS---PTP----- 1163

Query: 790  VSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLY 849
                    ++ MS   S+    +S +      S  ++      T    S   T G +   
Sbjct: 1164 --------KVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKS 1215

Query: 850  TRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSV- 908
            T      P  ATS +  + G+  ++   +S  ++ S+  G   + ++ ST  L   S V 
Sbjct: 1216 TLVPLDTPSPATSLEASEGGLPTLSTYPES-TNTPSIHLGAHASSESPSTIKLTMASVVK 1274

Query: 909  -SSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSG 967
              SY+ +T PS + T +   + + + +     S  E+  P E      + G  W   +  
Sbjct: 1275 PGSYTPLTFPSIE-THIHVSTARMAYSS---GSSPEMTAPGET-----NTGSTWDPTTYI 1325

Query: 968  LPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKA 1027
               DP+                    SAQ   P   +   +    P       A+  G  
Sbjct: 1326 TTTDPKDTS-----------------SAQVSTPHSVRTLRTTENHPKTESATPAAYSGSP 1368

Query: 1028 PLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATIT 1087
             +  S    SP+    +  D  +          A  S GF+  S  G  +++  +  TI 
Sbjct: 1369 KISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTI- 1427

Query: 1088 SGSATL---GKIPKSAAIGGKSN---------AGRKTSLDGSQNQDDVVLHVSSKTTLQY 1135
             GS+TL     +P    +   S              TSL       D+ +   S     +
Sbjct: 1428 -GSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTF 1486

Query: 1136 RSLP---------RPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGS 1186
               P           S++ TS I       + ++++D ++  +S G T      P     
Sbjct: 1487 AIFPPMSTPSHELSKSEADTSAI-----RNTDSTTLDQHLGIRSLGRTGDLTTVPI---- 1537

Query: 1187 GRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASP 1246
               +P+T   T   +      D+ S ++      SPT  +         P S  P   + 
Sbjct: 1538 ---TPLTTTWTSVIEHSTQAQDTLSATM------SPTHVTQSLKDQTSIPASASPSHLTE 1588

Query: 1247 TFRRLFGAKAGGKSASAPNTEGVKSSSVM----PSPSTTLARQGSLESPSSGTGSMGSAG 1302
             +  L      G+S+S   T    S+  +     +  T +     +++ ++G+ S G   
Sbjct: 1589 VYPEL---GTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTL 1645

Query: 1303 GLS----GSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSK 1358
            G++    G+SS     P++ +T   +++    SS A+V    + GL     + +S+ G  
Sbjct: 1646 GIAHLPIGTSS-----PAETST---NMALERRSSTATVSMAGTMGL-----LVTSAPGRS 1692

Query: 1359 DTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTT-GTHEVQSLLMRTGSVRSTLSESMQLD 1417
             + S   ++S+ + S +  +  S  GS   L T G   + S L  + +  S +S S+ L 
Sbjct: 1693 ISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLT 1752

Query: 1418 RN-TLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYH 1476
             + T P   + +   S    +E         S    +   + + L+S +  S+   GK  
Sbjct: 1753 SSPTTP--DVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEK 1810

Query: 1477 F----SNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSATSLEERPRAIS 1532
                  +L SPT   +   P  S+  SN+ P    S DL        + T   +R     
Sbjct: 1811 LRTASMDLPSPTPSMEVT-PWISLTLSNA-PNTTDSLDLSHGVHTSSAGTLATDRSLNTG 1868

Query: 1533 HSGSFR-DSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLT 1589
             + + R ++  +    SLS+ +ST +  +  E+   S  IH          E   T T
Sbjct: 1869 VTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTST 1926



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 276/1429 (19%), Positives = 506/1429 (35%), Gaps = 244/1429 (17%)

Query: 203  VTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSR----VP--- 255
            V+ +S PS+A  + T       +     T    S + +   K   LP P +    +P   
Sbjct: 2863 VSASSSPSKAFASLTTAPPTWGIPQSTLT-FEFSEVPSLDTKSASLPTPGQSLNTIPDSD 2921

Query: 256  AAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTA 315
            A+ +SS +  +   N R++   S       ++ +    ++ +G  S S      + P++ 
Sbjct: 2922 ASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSG 2981

Query: 316  GQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTV------KQSSTATSPTPSSDR---- 365
               P  A  S S   P ++ S     S  S + T+       +S +++SP   S      
Sbjct: 2982 TGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETS 3041

Query: 366  -LKPPVSEGVKTAPSGQKSMLEKFK-LVNARTALRPPQPPSSGPSDGGKDDDAFSESGEM 423
             L P  S   KT+     SM  +   LV+ +T+     P S+        + +  E  E+
Sbjct: 3042 FLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTL-------NMSQEEPPEL 3094

Query: 424  EGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKP 483
                +     G+T  +  ++     P     +L    S  +P  + + + +        P
Sbjct: 3095 TSSQTIAEEEGTTAETQTLT---FTPSETPTSLLPVSSPTEPTARRKSSPETWASSISVP 3151

Query: 484  VKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGS-------KVPT 536
             K    + T+     T K++S   +G+ T  A  E    S +G   PGS       K+ +
Sbjct: 3152 AKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGT-SPGSPEMSTTLKIMS 3210

Query: 537  VKQ-TISPGSTASKESEKFRTTKGS-PSQSLSKPITMEKASASSCPAPLEGREAGQASPS 594
             K+ +ISP   ++  +  ++T + + P ++  +P+T++  +  S    +     G  SP+
Sbjct: 3211 SKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPT 3270

Query: 595  GSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTS 654
             S T  +  +         V L      +  N  +  P         +  A  S+ S  S
Sbjct: 3271 KSPTENMLATE-------RVSLSPSPPEAWTNLYSGTP-----GGTRQSLATMSSVSLES 3318

Query: 655  PTKMDLSYS--KTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHST 712
            PT   ++ +  +++ + + + +G +       T     D   +L  + + L     S ++
Sbjct: 3319 PTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNS 3378

Query: 713  LETTFDST---VTTEVNGRTIPNL------------TSRPTPMTWRLGQACPRLQAGDAP 757
            + +  D +     T V+   IP+             TSR     +    +     +G   
Sbjct: 3379 VSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDI 3438

Query: 758  SLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDV 817
            +LGA    + T     T  +  + + P     ++ L N S                    
Sbjct: 3439 TLGASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPS-------------------- 3478

Query: 818  GGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVH----DV 873
            GG  S              ++  +T   + L T   N    +A   DI     H      
Sbjct: 3479 GGKTS--------------SASSVTSPSIGLETLRAN---VSAVKSDIAPTAGHLSQTSS 3521

Query: 874  TVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRST 933
              +    D +++ + G+S T+  + T+ ++TT+        T+ S   T+ RT S +  +
Sbjct: 3522 PAEVSILDVTTAPTPGISTTITTMGTNSISTTTPNPEVGMSTMDSTPATERRTTSTEHPS 3581

Query: 934  TDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGM 993
               TW S                A   W    + +  + + A    ++S   T S+    
Sbjct: 3582 ---TWSSTA--------------ASDSWTV--TDMTSNLKVARSPGTISTMHTTSF---- 3618

Query: 994  SAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAG----KSSGDEG 1049
                       A ++ L       D+ ++  G+  + G+SL    SDA     ++S  E 
Sbjct: 3619 ----------LASSTEL-------DSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSER 3661

Query: 1050 KKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAG 1109
               PS    ST  S+F   +   +    ++++S    T  S     +P S          
Sbjct: 3662 TLSPSDTTASTPISTFSRVQRMSISVPDILSTSW---TPSSTEAEDVPVS---------- 3708

Query: 1110 RKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSK 1169
               S D +  + D    +S   T  + SL     S+     GR     S SS  +  S+ 
Sbjct: 3709 -MVSTDHASTKTDPNTPLS---TFLFDSL-----STLDWDTGR-----SLSSATATTSAP 3754

Query: 1170 SAGATTSKLREPTKIGSGRSS-PVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASAC 1228
                T  +L   T I    S  P ++          A++ S  V+ S   +  PTS  A 
Sbjct: 3755 QGATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTFS---RPDPTSKKA- 3810

Query: 1229 GAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQG-- 1286
                  Q  ++ P   S        A  G    SA  T  V   +   +P  T  RQG  
Sbjct: 3811 -----EQTSTQLPTTTS--------AHPGQVPRSAATTLDVIPHTA-KTPDATFQRQGQT 3856

Query: 1287 SLESPSSGTGSMGSAGGLSGSSSP----LFNKPSDLT----TDVISLSHSLASSPASVHS 1338
            +L + +  T    +    S  S+P    + N  S+ T    T   S+  +L +   ++ S
Sbjct: 3857 ALTTEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLES 3916

Query: 1339 FTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESID----LPLSHHGSLSGLTTGTH 1394
             T+    W ++     A S+ T   +   ++H S+ +++    +  S H S S  T   H
Sbjct: 3917 GTTSSPSWKSSPYERIAPSESTTDKE---AIHPSTNTVETTGWVTSSEHASHS--TIPAH 3971

Query: 1395 EVQSLLMRTGSVRSTLSES-MQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQ 1453
               S L       ST  ++ + +   T P+       S+R   +      +         
Sbjct: 3972 SASSKLTSPVVTTSTREQAIVSMSTTTWPE-------STRARTEPNSFLTIELRDVSPYM 4024

Query: 1454 DTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYD 1513
            DT + +     S+  S+A  K   + + S   +S   L     MRS+  P++        
Sbjct: 4025 DTSSTTQTSIISSPGSTAITKGPRTEITSSKRISSSFL--AQSMRSSDSPSE-------- 4074

Query: 1514 DSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTA 1562
                  + T L   P A++ SG    +M+     + SL + T    +TA
Sbjct: 4075 ------AITRLSNFP-AMTESGGMILAMQTSPPGATSLSAPTLDTSATA 4116



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 132/579 (22%), Positives = 206/579 (35%), Gaps = 70/579 (12%)

Query: 964  VSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASE 1023
            +S G+PE        +++  S T      +S    +  R ++  S+L TP  +    A  
Sbjct: 310  LSPGVPEARASTMPNSAIPFSMT------LSNAETSAERVRSTISSLGTPSISTKQTAET 363

Query: 1024 KGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSG 1083
                     ++    +   K+   E    P  +G  T+TS+     PS    S    +  
Sbjct: 364  ILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLG-GTSTSALTTTSPSTTLVSEETNTHH 422

Query: 1084 ATITSGSATLGKIPKSAAIGGKSNAGRK-------------TSLDGSQNQDDVVLHVSSK 1130
            +T  SG  T G +  S      S  G +             T+LD        V   SS 
Sbjct: 423  ST--SGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVS--SSH 478

Query: 1131 TTLQYRSLPRPS--KSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGR 1188
             T + R+    S  +SS++   G      +T+S  S  SS ++ +T  +  EP       
Sbjct: 479  PTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQHTQWVE 538

Query: 1189 SSPVTVNQTDKEKEKVAVSDSESVS--LSG--SPKSSPTSA------SACGAQGLRQPGS 1238
            +SP    +       VA   + SV   +SG  + K+S T        SA    G    G 
Sbjct: 539  TSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGESTAGP 598

Query: 1239 KYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSM 1298
                 A PT   + G  +   S    +     ++S   S   TLA  G   S S      
Sbjct: 599  TTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKT 658

Query: 1299 GSAGGLSGSSSPLFNKPS-DLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGS 1357
             +     GSS P   KPS  + + VI  + SL SS     +F  G  +    +++    S
Sbjct: 659  AA-----GSSPPGGTKPSYTMVSSVIPETSSLQSS-----AFREGTSLGLTPLNTRHPFS 708

Query: 1358 KDTPSYQSMTSLHTS------------SESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGS 1405
               P     T + TS              S     SHH + S +TTGT E+ +    + +
Sbjct: 709  SPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSA 768

Query: 1406 VRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPS 1465
            V S    SM L       + +R   S        G+E   S  T         SP + P+
Sbjct: 769  VLS----SMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPT 824

Query: 1466 AMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPA 1504
               +S + +       SP+ LS  ++ G     S+S P+
Sbjct: 825  GTLTSESSE-------SPSTLSLPSVSGVKTTFSSSTPS 856



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 330/1611 (20%), Positives = 576/1611 (35%), Gaps = 257/1611 (15%)

Query: 209  PSEASQAKTQQDMQSSLAARYAT-QSNHSG-------------------IATSQKKPTRL 248
            PS+AS A T   + S L   ++T Q+  SG                    A++ +K +  
Sbjct: 2997 PSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLF 3056

Query: 249  PGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGN 308
             GPS          +Q  S L     S  ++ + +PP      E  SS+      G    
Sbjct: 3057 LGPSMARQPNILVHLQ-TSALTLSPTSTLNMSQEEPP------ELTSSQTIAEEEGTTAE 3109

Query: 309  VQPPS-TAGQPPASAIPSPSASKP----------WRSK-SMNVKHSATST-----MLTVK 351
             Q  + T  + P S +P  S ++P          W S  S+  K S   T     + T+K
Sbjct: 3110 TQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIK 3169

Query: 352  QSSTA-----TSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSG 406
             SS A     T P P+ +    P      T+P G   M    K+++++     P+  S+ 
Sbjct: 3170 MSSQAAQGNSTWPAPAEETGSSPAG----TSP-GSPEMSTTLKIMSSKEPSISPEIRSTV 3224

Query: 407  PSDGGKDDDA---FSESGEMEGFNSGLNSGGSTNSSPKVSPKLAPPKAGSKN-LSNKKSL 462
             +   K  +       + E     S     GST+ S   +   +P K+ ++N L+ ++  
Sbjct: 3225 RNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVS 3284

Query: 463  LQPKEKE--------------EKNRDKNKVCTEKPVKEE-----KDQVTEMAPKKTSKIA 503
            L P   E              +     + V  E P         +    E+  K T    
Sbjct: 3285 LSPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEF 3344

Query: 504  SLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPS- 562
            S+    +  T       + +SS I +     P    +++  S    ++E + +T   PS 
Sbjct: 3345 SMWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNSVSSLTDKS--KHKTETWVSTTAIPST 3402

Query: 563  ----------QSLSKPITMEKASASSCPAPLEGREAGQ-ASPSGSCTMTVAQSSGQSTGN 611
                      Q  S+ +    +S SS      G +    ASP  + T+ +  S+ Q+T  
Sbjct: 3403 VLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASPDVTNTLYIT-STAQTTS- 3460

Query: 612  GAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPT---KMDLSYSKTAKQ 668
              V LP   Q     T+   P          G    SA S TSP+   +   +     K 
Sbjct: 3461 -LVSLPSGDQGI---TSLTNP---------SGGKTSSASSVTSPSIGLETLRANVSAVKS 3507

Query: 669  CLEEISGEDPETRRMRTVKNIADLRQ----NLEETMSSLRGTQISHSTLE-----TTFDS 719
             +   +G   +T     V +I D+       +  T++++    IS +T       +T DS
Sbjct: 3508 DIAPTAGHLSQTSSPAEV-SILDVTTAPTPGISTTITTMGTNSISTTTPNPEVGMSTMDS 3566

Query: 720  TVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRF 779
            T  TE         TS   P TW    A       D  S        GT   +HT  + F
Sbjct: 3567 TPATE------RRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHT--TSF 3618

Query: 780  MYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSG 839
            + ++    +  +  G ++ I  S    S        D     ++     ++L   D  + 
Sbjct: 3619 LASSTELDSMSTPHGRITVIGTSLVTPSS-------DASAVKTETSTSERTLSPSDTTAS 3671

Query: 840  YMTDGGLNLYTRSLNRIPDT-ATSRDIIQRGVHDVTVDADSWDDSSSVS---SGLSDTL- 894
                    +   S++ +PD  +TS         DV V   S D +S+ +   + LS  L 
Sbjct: 3672 TPISTFSRVQRMSIS-VPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLF 3730

Query: 895  DNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSH 954
            D++ST D +T  S+SS +  T   +  T        +  T ET  SP   + P       
Sbjct: 3731 DSLSTLDWDTGRSLSSATATTSAPQGATT------PQELTLETMISPATSQLPFSIGHIT 3784

Query: 955  GDAGGKWKTVSSGL----PEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGT-SA 1009
                      SSG+    P+   K  ++ S  +  T       SA  G   R  A T   
Sbjct: 3785 SAVTPAAMARSSGVTFSRPDPTSKKAEQTSTQLPTT------TSAHPGQVPRSAATTLDV 3838

Query: 1010 LKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSSFGFKK 1069
            +    KT DA    +G+  L   +  R+ SD    S +E +K       ST ++ +  + 
Sbjct: 3839 IPHTAKTPDATFQRQGQTALTTEA--RATSD----SWNEKEK-------STPSAPWITEM 3885

Query: 1070 PSGVGSSAM--ITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTS-----LDGSQNQDD 1122
             + V    +  +TSS + +     TL  +  +   G  S+   K+S            D 
Sbjct: 3886 MNSVSEDTIKEVTSSSSVLR----TLNTLDINLESGTTSSPSWKSSPYERIAPSESTTDK 3941

Query: 1123 VVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSA--GATTSKLRE 1180
              +H S+ T      +     +S S IP        TS + +  + + A    +T+   E
Sbjct: 3942 EAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWPE 4001

Query: 1181 PTKIGSGRSSPVTVN--------QTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQG 1232
             T+  +  +S +T+          T    +   +S   S +++  P++  TS+    +  
Sbjct: 4002 STRARTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGSTAITKGPRTEITSSKRISSSF 4061

Query: 1233 LRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPS 1292
            L Q   +  D  S    RL    A  +S        + +    P  +T      SL +P+
Sbjct: 4062 LAQ-SMRSSDSPSEAITRLSNFPAMTESGGM-----ILAMQTSPPGAT------SLSAPT 4109

Query: 1293 SGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSS 1352
              T +  S  G   +++  F      T        +   SP SV   +S   +   + ++
Sbjct: 4110 LDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATT 4169

Query: 1353 SSAGSKDTPSYQSMTSL-HTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGS-----V 1406
            S       PS   +TS  H+ S +  +        SGL   T ++  + +  G+     +
Sbjct: 4170 S-------PSNILLTSQGHSPSSTPPVTSVFLSETSGLGKTT-DMSRISLEPGTSLPPNL 4221

Query: 1407 RSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSA 1466
             ST  E++     +   K + ++  +   N E       S   G  + +   SPLV+   
Sbjct: 4222 SSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEY-SPIPGHTKPSKATSPLVTSHI 4280

Query: 1467 M-----SSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQLCGSA 1521
            M     S+S  G    + + + ++++Q  L   S  +  S   + S+   +  S   G A
Sbjct: 4281 MGDITSSTSVFGSSETTEIETVSSVNQ-GLQERSTSQVASSATETSTVITHVSS---GDA 4336

Query: 1522 TSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVAS 1581
            T+   + +A   SG+   S+   H      ++ST++    +   + S         L+ +
Sbjct: 4337 TTHVTKTQATFSSGT---SISSPH----QFITSTNTFTDVSTNPSTS---------LIMT 4380

Query: 1582 QEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEMLKAQN 1641
            +    T+T+Q        AA +      T  +  LT T      + ++  +T  + K   
Sbjct: 4381 ESSGVTITTQTGPTG---AATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPK 4437

Query: 1642 --------SAAQAAIQGALNG---PDHPPKDLRIRRQHSSESVSSINSATS 1681
                    S A+ +   +L        PP    ++ QH+S  VS+ +  TS
Sbjct: 4438 DVSWTSPPSVAETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLTS 4488



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 115/492 (23%), Positives = 182/492 (36%), Gaps = 81/492 (16%)

Query: 1043 KSSGDEGKKPPSGIGRSTATSSFGFKKP----SGVGSSAMI--TSSGATI--------TS 1088
            K SG  G   P+   RS  T S   K      SG+  + +   TS+GA +        TS
Sbjct: 3    KPSGLPGSSSPT---RSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVVTEHTLPFTS 59

Query: 1089 GSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTL----QYRSLPRPSKS 1144
               TL   P S+ +G  + +    S    ++    + H   +T+     Q    P  +  
Sbjct: 60   PDKTLAS-PTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYP 118

Query: 1145 STSGIPGRGGHRSSTSSIDSNVSSKSA----------GATTSKLREPTKIGSGRS-SPVT 1193
            +TS + G    R+ TSS + N + +++          G  T K   PT+  +    S  T
Sbjct: 119  ATSMVSGLSSPRTRTSSTEGNFTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTET 178

Query: 1194 VNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFG 1253
               T     K+          + S +++P S +           S  P   +P+F  L+ 
Sbjct: 179  PWDTRYIPVKITSPMKTFADSTASKENAPVSMTPAETT---VTDSHTPGRTNPSFGTLYS 235

Query: 1254 AKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFN 1313
            +         PN+ G  S  ++ S  TT     S E  S+G   + ++  LS S+S L N
Sbjct: 236  SFLDLSPKGTPNSRGETSLELILS--TTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDN 293

Query: 1314 KPSD------------LTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTP 1361
            K S+            L+  V     S   + A   S T      +A    S+  S  TP
Sbjct: 294  KISETSIFSGQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTP 353

Query: 1362 SY------QSMTSLHTSSESIDLPLSH------------HGSLSGLTTGTHEVQSLLMRT 1403
            S       +++ + H  +E++D+P +H             G+L G +T      S L  T
Sbjct: 354  SISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTST------SALTTT 407

Query: 1404 GSVRSTLSESMQLDRNTLPKK-----GLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQ 1458
                + +SE      +T  K+         TP    A  EE +       T G   T   
Sbjct: 408  SPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGF--TTLD 465

Query: 1459 SPLVSPSAMSSS 1470
            S + SPS +SSS
Sbjct: 466  SKIRSPSQVSSS 477



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 300/1502 (19%), Positives = 512/1502 (34%), Gaps = 274/1502 (18%)

Query: 216  KTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKVQGASNLNRRSQS 275
            K   +M S L     +    +G     +       P +  A+ +SS V       R +QS
Sbjct: 25   KATPEMDSGLTGATLSPKTSTGAIVVTEHTLPFTSPDKTLASPTSSVV------GRTTQS 78

Query: 276  FNSIDKNKPPNYANG-NEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRS 334
               +    P + + G    +    P  S  VNG    PS     PA+++ S  +S   R+
Sbjct: 79   LGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGT---PSR--NYPATSMVSGLSSPRTRT 133

Query: 335  KSM--NVKHSATSTMLTVKQSS----------TATSPTPSSDRLKP--------PVSEGV 374
             S   N    A++  LTV+ +S          T TS T       P         ++  +
Sbjct: 134  SSTEGNFTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPM 193

Query: 375  KTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSGG 434
            KT      S        NA  ++ P +   +     G+ + +F   G +      L+  G
Sbjct: 194  KTFADSTASK------ENAPVSMTPAETTVTDSHTPGRTNPSF---GTLYSSFLDLSPKG 244

Query: 435  STNSSPKVSPKL---------APPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVK 485
            + NS  + S +L         + P+ GS   S + S   P        D NK+ +E  + 
Sbjct: 245  TPNSRGETSLELILSTTGYPFSSPEPGSAGHS-RISTSAPLSSSASVLD-NKI-SETSIF 301

Query: 486  EEKDQVTEMAPKKTSKIASLIPKGS----------KTTAAKKESLIPSSSGIPKPGSK-- 533
              +   + ++P      AS +P  +          +T+A +  S I SS G P   +K  
Sbjct: 302  SGQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETSAERVRSTI-SSLGTPSISTKQT 360

Query: 534  ---------------VPT--VKQTI------SPGSTASKESEKFRTTKGSPSQSLSKPIT 570
                           +P+  + +T+      SPG+     +    TT  SPS +L    T
Sbjct: 361  AETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTT--SPSTTLVSEET 418

Query: 571  MEKASAS---------SCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQ 621
                S S         +   PLE    G+ S     T T+  + G +T +  ++ P Q  
Sbjct: 419  NTHHSTSGKETEGTLNTSMTPLETSAPGEES---EMTATLVPTLGFTTLDSKIRSPSQVS 475

Query: 622  HSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETR 681
             SHP               +   A  S+D   + T    S SK +    E  + +  E +
Sbjct: 476  SSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTS---STSKASSWTSESTAQQFSEPQ 532

Query: 682  RMRTVKNIADLRQNLEETMSSLRGTQISHST-LETTFDSTVTTEVNGRTIPNLTSRPTPM 740
              + V           ET  S++  +   ST +     ++V + V+G T   L +  T  
Sbjct: 533  HTQWV-----------ETSPSMKTERPPASTSVAAPITTSVPSVVSGFT--TLKTSSTKG 579

Query: 741  TWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQID 800
             W        L+   A +L  G   +G +      P+    T        S  G+     
Sbjct: 580  IW--------LEETSADTL-IGESTAGPTTHQFAVPTGISMT-----GGSSTRGSQGTTH 625

Query: 801  MSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLN-LYTRSLNRIPDT 859
            +  +A++  + S+++ +    ++G  +  S       +G    GG    YT   + IP+T
Sbjct: 626  LLTRATASSETSADLTLA---TNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPET 682

Query: 860  ATSRDIIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSR 919
            ++ +    R     ++     +     SS   D     S      ++S+   S+ +V   
Sbjct: 683  SSLQSSAFR--EGTSLGLTPLNTRHPFSSPEPD-----SAGHTKISTSIPLLSSASVLED 735

Query: 920  KNTQLRTDSEKRSTTDETWDSPEELKKPEED--------FDSHGDAGGKWKTVSSGL--- 968
            K +   T S  ++T+  T  +PE   K +            +   +  + +  +S L   
Sbjct: 736  KVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHP 795

Query: 969  -PEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKA 1027
             P   E AG   +LS S   +    +   G   S      S L  P      K +     
Sbjct: 796  SPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLP-SVSGVKTTFSSST 854

Query: 1028 PLKGSSLQRSPSDAGKSSGDEGKKPPSGIGR-STATSSFGFKKP---------------- 1070
            P   + L  S  +  ++S     +P + + R  T  +S     P                
Sbjct: 855  P--STHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFS 912

Query: 1071 -SGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSS 1129
             S + S    TSS +   S  + L KI         S   R T  D +  Q       S 
Sbjct: 913  SSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWPETSP 972

Query: 1130 KTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREP------TK 1183
            +       LP    S+T+ +       S+T  +    S  ++    + +REP      T+
Sbjct: 973  RFK---TGLP----SATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTE 1025

Query: 1184 IGSGRSSP-------------VTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGA 1230
              +G  S              +T  + D     +  + S   S+  +      S S   +
Sbjct: 1026 TTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPS 1085

Query: 1231 QGLRQPGSKYP------------DIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSP 1278
            Q +   GS  P            D+   T R +   + G  SA  P      +++  PSP
Sbjct: 1086 QSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQ----MTATHPPSP 1141

Query: 1279 STTLARQGSL----ESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPA 1334
                AR   L     SPSS T  +  +   S          + +  D +  S     +  
Sbjct: 1142 DPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQ-----RVTTSMIMDTVETSRWNMPNLP 1196

Query: 1335 SVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTH 1394
            S  S T   +  +  +  S+    DTPS    TSL  S           G L  L+T   
Sbjct: 1197 STTSLTPSNIPTSGAIGKSTLVPLDTPS--PATSLEAS----------EGGLPTLSTYPE 1244

Query: 1395 EVQSLLMRTGSVRSTLSES-MQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSH---STG 1450
               +  +  G+  S+ S S ++L   ++ K G  YTP +  +        + +H   ST 
Sbjct: 1245 STNTPSIHLGAHASSESPSTIKLTMASVVKPG-SYTPLTFPS--------IETHIHVSTA 1295

Query: 1451 GLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFD 1510
             +  +   SP         +A G+ +  +   PT       P  +     S P    +  
Sbjct: 1296 RMAYSSGSSP-------EMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLR 1348

Query: 1511 LYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQ 1570
              ++     SAT         ++SGS + S      SS +L S  +  ++  +   HS Q
Sbjct: 1349 TTENHPKTESAT-------PAAYSGSPKIS------SSPNLTSPATKAWTITDTTEHSTQ 1395

Query: 1571 IH 1572
            +H
Sbjct: 1396 LH 1397



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 211/1031 (20%), Positives = 383/1031 (37%), Gaps = 133/1031 (12%)

Query: 490  QVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGSKVPTV----KQTISPGS 545
            +VT  +   T ++ + +   +  T+      +PS++ +    S +PT     K T+ P  
Sbjct: 1164 KVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTP--SNIPTSGAIGKSTLVPLD 1221

Query: 546  TASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSG-SCTMTVAQS 604
            T S  +    +  G P+ S     T       + P+   G  A   SPS    TM     
Sbjct: 1222 TPSPATSLEASEGGLPTLSTYPEST-------NTPSIHLGAHASSESPSTIKLTMASVVK 1274

Query: 605  SGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSK 664
             G  T    +  P  + H H +TA +A   Y + S  E TA    ++ T  T    +Y  
Sbjct: 1275 PGSYT---PLTFPSIETHIHVSTARMA---YSSGSSPEMTA--PGETNTGSTWDPTTYIT 1326

Query: 665  TAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTE 724
            T     +  S +      +RT++   +  +    T ++  G+    S+   T  +T    
Sbjct: 1327 TTDP-KDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPAT---- 1381

Query: 725  VNGRTIPNLTSRPTPMTW-RLGQACPRLQAGDAPS----LGAGYPRSGTSRFIHTD--PS 777
                TI + T   T + + +L +     +   AP     +    P  G+S    T   P 
Sbjct: 1382 -KAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPG 1440

Query: 778  RFMYTTPLRRAAVSR-LGNMSQIDMSEK-ASSDLDMSSEVDVGGYMS--------DGDIL 827
              +   P  +  ++  +       ++E+ AS+DLD+SS        +          ++ 
Sbjct: 1441 EPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELS 1500

Query: 828  GKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSSSVS 887
                 T  I +   T    +L  RSL R  D  T   I        +V   S     ++S
Sbjct: 1501 KSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTV-PITPLTTTWTSVIEHSTQAQDTLS 1559

Query: 888  SGLSDTLDNISTDDLNTTSSVSSYSNIT-VPSRKNTQLRTDSEK----RSTTD------E 936
            + +S T    S  D  +  + +S S++T V     TQ R+ SE     + +TD      E
Sbjct: 1560 ATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIE 1619

Query: 937  TWDSPEELKKPEEDFDSHGDAGGKWKTV-------SSGLPEDPEKAGQKASLSVSQTGSW 989
            T  +  +   P ++  +   + G    +       SS        A ++ S + + + + 
Sbjct: 1620 TGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAG 1679

Query: 990  RRGM---SAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSG 1046
              G+   SA G + S+     S++ +   T+    S KG +P   +    + S + + S 
Sbjct: 1680 TMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSY 1739

Query: 1047 DEGKKPPSGIGRSTAT----------SSFGFKKPSGVGSSAMITSSGATITSGSATLGKI 1096
             EG +  + I  +++           S+F  K+ + V +S  I+ S A   S SATL   
Sbjct: 1740 AEGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSD-ISKSSARTESSSATL--- 1795

Query: 1097 PKSAAIGGKSNAGRKTSLDGSQNQDDVV--LHVSSKTTLQYRSLPRPSKSSTSGIPGRGG 1154
              S A+G   N G++     S +       + V+   +L   + P  + S        G 
Sbjct: 1796 -MSTALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDL---SHGV 1851

Query: 1155 HRSSTSSIDSNVSSKSAGATTSKLREPTKIGS-----GRSSPVTVNQTDKEKEKVAVSDS 1209
            H SS  ++ ++ S  +     S+L   +   S     G S+  ++  T+K +   ++   
Sbjct: 1852 HTSSAGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPR 1911

Query: 1210 ESVSLSGSPKSSPTSASACGAQGLRQPGSKYP--DIASPTFRRLFGAKAGGKSASAPNTE 1267
               S  G+ +++ TS     A  L  P S  P  ++ S       G  +G    SAP T 
Sbjct: 1912 PETSAPGA-ETTLTSTPGNRAISLTLPFSSIPVEEVIST------GITSGPDINSAPMTH 1964

Query: 1268 GVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAG-GLSGSSSPLFNKPSDLTTDVISLS 1326
                 S +  P+      G++E  +    ++ S    +   S+P  N  +   +     S
Sbjct: 1965 -----SPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENS 2019

Query: 1327 HSLASSPASVHSFTS--------------GGLVWAANMSSSSAGSKDTPSYQSMTSLHT- 1371
             S  SS +S +S  S                 +W    S  +     T   ++++S H+ 
Sbjct: 2020 VSSGSSTSSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSG 2079

Query: 1372 ----SSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLR 1427
                SS + + PL    S S       E +     T   ++T + ++  D +++   GL 
Sbjct: 2080 VSNPSSTTTEFPLFSAASTSAAKQRNPETE-----THGPQNTAASTLNTDASSV--TGLS 2132

Query: 1428 YTPSSRQANQE 1438
             TP     + E
Sbjct: 2133 ETPVGASISSE 2143



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 242/1257 (19%), Positives = 413/1257 (32%), Gaps = 162/1257 (12%)

Query: 312  PSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVS 371
            P T G    SA+ + S S    S+  N  HS TS   T    +T+ +P  +S   +    
Sbjct: 393  PGTLGGTSTSALTTTSPSTTLVSEETNTHHS-TSGKETEGTLNTSMTPLETSAPGEESEM 451

Query: 372  EGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGFNSGLN 431
                    G  ++  K +  +  ++  P +   +  S  G+   + +  G  +   +   
Sbjct: 452  TATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRA--- 508

Query: 432  SGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQV 491
               +T+S+ K S   +   A   +       ++     +  R         P+      V
Sbjct: 509  ---TTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSV 565

Query: 492  TE-MAPKKTSKIASLIPKGSKTTAAKKESLIPSSSGIPKPGS-KVPTVKQTISPGSTASK 549
                   KTS       KG        ++LI  S+  P      VPT        ST   
Sbjct: 566  VSGFTTLKTSST-----KGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGS 620

Query: 550  ESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSG----SCTMTVA--- 602
            +      T+ + S   S  +T+         +P   + A  +SP G    S TM  +   
Sbjct: 621  QGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIP 680

Query: 603  -----QSSGQSTGNGAVQLPQQQQH----------SHPNTATVAPFIYRAHSENEGTALP 647
                 QSS    G      P   +H           H   +T  P +  A    +     
Sbjct: 681  ETSSLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKV--- 737

Query: 648  SADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQ 707
            SA S  S  K   S +    +   +          M T+ N A   + +    S L    
Sbjct: 738  SATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSM-TLSNAATSPERVRNATSPLTHPS 796

Query: 708  ISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSG 767
             S    E T  S +T   +  T  +    PT             ++ ++PS  +    SG
Sbjct: 797  PSG---EETAGSVLTLSTSAETTDSPNIHPTGTLTS--------ESSESPSTLSLPSVSG 845

Query: 768  T-SRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDV--------- 817
              + F  + PS  ++T+       S   ++SQ + S         S+ V           
Sbjct: 846  VKTTFSSSTPSTHLFTSGEETEETSN-PSVSQPETSVSRVRTTLASTSVPTPVFPTMDTW 904

Query: 818  ---GGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVT 874
                   S   ++ +   T   +    T   L   +        + T+RD          
Sbjct: 905  PTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFN---DSAA 961

Query: 875  VDADSWDDSSS-VSSGLSDTLDNISTD--DLNTTSSVSSYSNITVPSRKNTQLRTDSEKR 931
              + +W ++S    +GL      +ST    L+ T  VS +++    S + T +R  S   
Sbjct: 962  PQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTI 1021

Query: 932  STTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRR 991
             TT ET + P  +     +        GK       L       G  AS   S   +  +
Sbjct: 1022 LTT-ETTNGPGSMAVASTNIPI-----GKGYITEGRLDTSHLPIGTTASSETSMDFTMAK 1075

Query: 992  GMSAQGGAPSRQKAGTSALKTPGKTD---DAKASEKGKAPLKGSSLQRSPSDAGKSSGDE 1048
               +   +PS Q    +   TPG+T    D  + +      +  ++ R  + +  +    
Sbjct: 1076 ESVSMSVSPS-QSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMT 1134

Query: 1049 GKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIG--GKS 1106
               PPS    S  ++  G    S    +  +T S +T ++   T   I  +         
Sbjct: 1135 ATHPPSPDPGSARSTWLGILSSSPSSPTPKVTMS-STFSTQRVTTSMIMDTVETSRWNMP 1193

Query: 1107 NAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTS--SIDS 1164
            N    TSL  S       +  S+   L   S     ++S  G+P    +  ST+  SI  
Sbjct: 1194 NLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPESTNTPSIHL 1253

Query: 1165 NVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTS 1224
               + S   +T KL   + +  G  +P+T    +     + VS +     SGS   SP  
Sbjct: 1254 GAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETH---IHVSTARMAYSSGS---SPEM 1307

Query: 1225 ASACGAQGLRQPGSKYP-----------DIASPTFRRLFGAKAGGKSASAPNTEG----- 1268
                 A G    GS +            D +S         +    + + P TE      
Sbjct: 1308 T----APGETNTGSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAA 1363

Query: 1269 ------VKSSSVMPSPST------------TLARQGSLESPSSGTGSMGSAGGLS---GS 1307
                  + SS  + SP+T            T      L   SSG  +  + G +S    +
Sbjct: 1364 YSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPT 1423

Query: 1308 SSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMT 1367
            S  + +   +LT+DV      L  +P+   + T     W +   +    S D        
Sbjct: 1424 SPTIGSSTLELTSDVPG--EPLVLAPSEQTTITLPMATWLSTSLTEEMASTD-------- 1473

Query: 1368 SLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQL----------- 1416
             L  SS S   P+S       ++T +HE+      T ++R+T S ++             
Sbjct: 1474 -LDISSPSS--PMSTFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTG 1530

Query: 1417 DRNTLPKKGLRYTPSSRQANQEEGKEWLR-----SHSTGGLQDTGNQSPLVSPSAMS 1468
            D  T+P   L  T +S   +  + ++ L      +H T  L+D  +     SPS ++
Sbjct: 1531 DLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPASASPSHLT 1587



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 303/1428 (21%), Positives = 509/1428 (35%), Gaps = 265/1428 (18%)

Query: 204   THASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRLPGPSRVPAAGSSSKV 263
             TH SP S  + + T +   SS+   Y T    + + TS             PA   +S++
Sbjct: 9234  THESPSSVLADSVTTK-ATSSMGITYPT--GDTNVLTS------------TPAFSDTSRI 9278

Query: 264   QGASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAI 323
             Q  S L+              P     +  + +      S V  +V   +T       AI
Sbjct: 9279  QTKSKLSLT------------PGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAI 9326

Query: 324   PSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKS 383
              S   S P  ++S     S+ ++M T+ + ST  +   S+D    P     KT PSG  S
Sbjct: 9327  SSSRTSIPGPAQSTM---SSDTSMETITRISTPLTRKESTDMAITP-----KTGPSGATS 9378

Query: 384   MLEKFKLVNARTALRP----------PQPPSSGPSDGGKDDDAFSESGEMEGFNSGLNSG 433
                 F L ++ TA  P          PQ   + P   G +D ++     +E  NS  +S 
Sbjct: 9379  Q-GTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPSPLSVEK-NSPPSSL 9436

Query: 434   GSTNSSPKVSPKLAPPKAGSKN----LSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKD 489
              S++S    SP  + P   S +    +++  + +  K  +  +       T  P      
Sbjct: 9437  VSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLDASLEPETTSAPNMNITS 9496

Query: 490   QVTEMAPKKTSKIASL------IPKGSKTTAAKKESLIPSSSGIPKPGSKVPTVKQTISP 543
               +  A K T++  ++           +TT+A +E  + SSS    PG   PT  + ISP
Sbjct: 9497  DESLAASKATTETEAIHVFENTAASHVETTSATEE--LYSSS----PGFSEPT--KVISP 9548

Query: 544   GSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQ 603
               T+S   +   +T    S  +++   +E  S SS    L      Q   S + T TV  
Sbjct: 9549  VVTSSSIRDNMVSTTMPGSSGITR---IEIESMSSLTPGLRETRTSQDITSSTETSTVL- 9604

Query: 604   SSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAH-SENEGTALPSADSCTSPTKMDLSY 662
                               +  P+ AT  P + R     +  T++P     T    +D+S 
Sbjct: 9605  ------------------YKMPSGAT--PEVSRTEVMPSSRTSIPGPAQSTM--SLDISD 9642

Query: 663   SKTAKQCLEEISGEDPE-TRRMRTVKNIADLRQNLE--ETMSSLRGTQISHSTLETTFDS 719
                 +     I  E  E T   +T  ++A  +  L    +M+ L GT   HST+      
Sbjct: 9643  EVVTRLSTSPIMTESAEITITTQTGYSLATSQVTLPLGTSMTFLSGT---HSTMSQGLSH 9699

Query: 720   TVTTEVNGRTIPNLTSR-PTPMTWRLGQACPRLQAGDA----PSLGAGYPRSGTSRFIHT 774
             +  T        NL SR P  ++W   +     ++  +    P   +  P S T   + +
Sbjct: 9700  SEMT--------NLMSRGPESLSWTSPRFVETTRSSSSLTSLPLTTSLSPVSST--LLDS 9749

Query: 775   DPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSS-EVDVGGYMSDGDILGKSLRT 833
              PS  +  T L    + +   +       K SS  ++SS  V++                
Sbjct: 9750  SPSSPLPVTSLILPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPA-------------- 9795

Query: 834   DDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHDV--TVDADSWDDSSSVSSGLS 891
                 S  MTD      T  ++   +TA ++      VH+   +V ADS    +  S G++
Sbjct: 9796  ---TSEIMTD------TEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTITIPSMGIT 9846

Query: 892   DTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDF 951
               +D+ +      TS+ +      +P+     L     + ST++ET    E         
Sbjct: 9847  SAVDDTTV----FTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLYGVP 9902

Query: 952   DSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALK 1011
              S        + +SS     P+      S  +  T    R  S+   + S Q   T+   
Sbjct: 9903  TSATTEVSMTEIMSSNRIHIPDSDQSTMSPDII-TEVITRLSSSSMMSESTQMTITTQKS 9961

Query: 1012  TPGKTDDAKAS-EKGKAPLKGSS---------------LQRSPSDAGKSSGDEGKKPPSG 1055
             +PG T  +  +     APL  +                + RSP +    S    +K  S 
Sbjct: 9962  SPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSS- 10020

Query: 1056  IGRSTATSSFGFKKPSGVGSSA--MITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTS 1113
                S++  S        V S+    I SS  ++TS   T G + K+     +       +
Sbjct: 10021 ---SSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTS-LLTPGMV-KTTDTSTEPGTSLSPN 10075

Query: 1114  LDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTS-GIPGRGGHRSSTSSIDSNVSSKSAG 1172
             L G+  +   +L  S  TT   +  P  S + T+ G    G    S+ SI S  S  +  
Sbjct: 10076 LSGTSVE---ILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYP 10132

Query: 1173  ATTSKLREPTKIGSGRSSPVTVNQTDKEKE----------KVAVS-DSESVSLSGSPKSS 1221
               T      T I +  S P     T  E E          K  +S D+ SV+ + +P SS
Sbjct: 10133 VGTPSSMAETSIST--SMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTP-SS 10189

Query: 1222  PTS------------ASACGAQGLRQPGSKYPDI---------ASPTFRRLFGAKAGGKS 1260
             P S            +SA  +     P S+Y +I         ASP+     G  +  +S
Sbjct: 10190 PGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPES 10249

Query: 1261  ASA---------------PNTEGVKSSSVMPSPSTTLARQGSLESPS--SGTGSMGS--- 1300
                               P+ E + + +VMPS S  +    +   P   SG+GS  S   
Sbjct: 10250 RFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTE 10309

Query: 1301  -----------AGGLSGSSSPLFNKPSDLTTD--VISLSHSLASSPASVH---------- 1337
                        A  L  S+   F+  +  TTD   I   H + SS A+ +          
Sbjct: 10310 SGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTES 10369

Query: 1338  SFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQ 1397
             S T G LV  + + +SS   + + S    T +   +ES++L         G  T  ++V 
Sbjct: 10370 STTEGRLVMVSTLDTSSQPGRTSSSPILDTRM---TESVEL---------GTVTSAYQVP 10417

Query: 1398  SLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGN 1457
             SL  R       +    ++      +  +R     + +      + L +  T  ++ T  
Sbjct: 10418 SLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTT 10477

Query: 1458  QSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQ 1505
                  + +  ++S A     +++ +PT L        SM  +++IP +
Sbjct: 10478 ALKTTTTALKTTSRATL--TTSVYTPT-LGTLTPLNASMQMASTIPTE 10522



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 255/1301 (19%), Positives = 439/1301 (33%), Gaps = 229/1301 (17%)

Query: 319   PASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSP------------------- 359
             P +  PS S++ P    S +   ++  T   VK + T+T P                   
Sbjct: 10028 PVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLSPNLSGTSVEILAAS 10087

Query: 360   --TPSSDRLKPPVSEGVK---TAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDD 414
               T  ++++ P  S  V    T  SG     E +  V+  +       P   PS   +  
Sbjct: 10088 EVTTDTEKIHPSSSMAVTNVGTTSSGH----ELYSSVSIHSEPSKATYPVGTPSSMAETS 10143

Query: 415   DAFSESGEME--GFN--------SGLNSGGSTNSSPKVSPKLAPPKAGSKNL--SNKKSL 462
              + S     E  GF         SG      +  +  V+P   P   GS +L  S+K   
Sbjct: 10144 ISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSKTDF 10203

Query: 463   LQPKEKEEKNRDKNKVCTEKPVK-----EEKDQVTEMAPKKTSKIASLIPKGSKTTAAKK 517
                 +    +       TE PV           +TE     +   +      +++T    
Sbjct: 10204 TSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFTMSVTESTHHLS 10263

Query: 518   ESLIPSSSGIPKPGSKVPTVKQTIS-------PGSTASKESEKFRTTKGSPSQSLSKPIT 570
               L+PS+  I   G+ +P++ + ++       P + +   S   RT  G    +LS   T
Sbjct: 10264 TDLLPSAETI-STGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLS---T 10319

Query: 571   MEKASASSCPAPLEG--------------REAGQASPSGSCTMTVAQSSGQSTGNGAVQL 616
             + ++  SS P P                  E   +S +     T   +   +T    V +
Sbjct: 10320 IAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMV 10379

Query: 617   PQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGE 676
                   S P   + +P +    +E+      ++          L+ +    + + +I  E
Sbjct: 10380 STLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGIMEHITKIPNE 10439

Query: 677   DPETRRMRTVKNIADLR-------------QNLEETMSSLRGTQISHSTLETTFDSTVTT 723
                   +R VK                   + +E T ++L+ T    + L+TT  +T+TT
Sbjct: 10440 AAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTT---TALKTTSRATLTT 10496

Query: 724   EVNGRTIPNLT----------SRPTPM---TWRLGQACPRLQAGDAPSLGAGYPRSGTSR 770
              V   T+  LT          + PT M   T  +    P   +  A SLGA      ++ 
Sbjct: 10497 SVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLGA----ETSTA 10552

Query: 771   FIHTDPSRFMYTTPLRRAAVSRLG--NMSQIDMSEKASSDLDMS--------------SE 814
                T PS F   +    + VSR G      I   + +SS+ D +              S+
Sbjct: 10553 LPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPTVSK 10612

Query: 815   VDVGGYMSDGDILGKSLRTD--DINSGYMTDGGLNLYTRSLNRIP--------DTATSRD 864
                  + S+ D +  +  +   D++S   T    N+    L+ +         DT+T+  
Sbjct: 10613 TTPNFFHSELDTVSSTATSHGADVSSAIPT----NISPSELDALTPLVTISGTDTSTTFP 10668

Query: 865   IIQRGVHDVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSV--------SSYSNITV 916
              + +  H+           +  SS +  T+ N S  + + T S+        SS   I  
Sbjct: 10669 TLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMT 10728

Query: 917   PSRKNTQLRTDSEKRSTTDETWDSPEELKKPEE-----DFDSHGDA-------------- 957
              S     L T     S TD     P     P E        +H +A              
Sbjct: 10729 VSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPA 10788

Query: 958   ------------GGKWKTVSSGLPEDPEKAGQKASL-----SVSQTGSWRRG-------- 992
                           K  T +  L   P +     SL       S T  W           
Sbjct: 10789 VSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSD 10848

Query: 993   ----MSAQGGAPSRQKAGTSALKT--PGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSG 1046
                 M+   GA S     T  + T  PG       S +         L  SP +   +  
Sbjct: 10849 TTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPS 10908

Query: 1047  ---DEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIG 1103
                  G++  S I   T +        S V SS  +TS+   I + S    +   S A  
Sbjct: 10909 MATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATS 10968

Query: 1104  GKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPR----PSKSSTSGIPGRGGHRSST 1159
               + AG        +    V   V+S   +   +LP     P +  T+       H +  
Sbjct: 10969 HGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATS-HGAEA 11027

Query: 1160  SSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPK 1219
             SS    VS +  G  TS +   + + S  S P  +    + +   +++ S     S +  
Sbjct: 11028 SSTVPTVSPEVPGVVTSLVTSSSGVNS-TSIPTLILSPGELETTPSMATSHGAEASSAV- 11085

Query: 1220  SSPTSASACGAQGLRQP-GSKYPDIASPTFRRL-FGAKAGGKSASAPNTEGVKSSSVMPS 1277
               PT   + G  G+  P  +    + S T   L   +     + S   + GV++SS + +
Sbjct: 11086 --PTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLT 11143

Query: 1278  PSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSD---LTTDVISLSHS--LASS 1332
              S         E P   T  + S+  ++ ++ P     SD    TT +++ S +  +++ 
Sbjct: 11144 VSP--------EVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAI 11195

Query: 1333  PASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTG 1392
             P    S T  GLV +   SS S    +T ++ ++T   +  E+ID  ++H G     T  
Sbjct: 11196 PTLAVSPTVQGLVTSLVTSSGS----ETSAFSNLTVASSQPETIDSWVAHPG-----TEA 11246

Query: 1393  THEVQSLLMRTGSVRSTLS--ESMQLDRNTLPKKGLRYTPS 1431
             +  V +L + TG   + +S         +TLP+   R++ S
Sbjct: 11247 SSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHS 11287



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 343/1730 (19%), Positives = 604/1730 (34%), Gaps = 303/1730 (17%)

Query: 294  DSSKGP------QSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTM 347
            DSSKG       Q ++ ++ +++P    G   +++IP  S+       + +V+    ST 
Sbjct: 1714 DSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPT-----TPDVEFIGGSTF 1768

Query: 348  LTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGP 407
             T + ++  TS    S       S  + +   G      K KL  A   L  P P     
Sbjct: 1769 WTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSPTP----- 1823

Query: 408  SDGGKDDDAFSESGEMEGFNS-GLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPK 466
                        S E+  + S  L++  +T  S  +S  +    AG+  L+  +SL    
Sbjct: 1824 ------------SMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGT--LATDRSLNTGV 1869

Query: 467  EKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSSSG 526
             +  +  + +   + K +       T M   + S+++S I    +T+A   E+ + S+ G
Sbjct: 1870 TRASRLENGSDT-SSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPG 1928

Query: 527  -----IPKPGSKVPTVKQTISPGSTASKESEKFR-------------TTKGSPSQSLSK- 567
                 +  P S +P V++ IS G T+  +                  T+ G+  QS    
Sbjct: 1929 NRAISLTLPFSSIP-VEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPL 1987

Query: 568  -PITMEKASASSCPAPLEGREAGQASP-------SGSCTMTVAQSSGQ-------STGNG 612
              ++ EK S  +   P     A  ASP       SGS T +   S+         S  N 
Sbjct: 1988 HAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNA 2047

Query: 613  AVQLPQQQQHSHPNTATVAPFIYRAHSE-NEGTALPSADSCTSPTKMDLSYSKTAKQCLE 671
                      S P T   +  +  A S  + G + PS+ +   P     S S  AKQ   
Sbjct: 2048 ITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTS-AAKQRNP 2106

Query: 672  EISGEDPETRRMRTVKNIADLRQNLEETMSSLRGTQISHSTLETTFDSTVTTEVNGRTIP 731
            E     P+     T+   A     L ET     G  IS S +      T  ++V+G    
Sbjct: 2107 ETETHGPQNTAASTLNTDASSVTGLSETPV---GASIS-SEVPLPMAITSRSDVSG---- 2158

Query: 732  NLTSRPTPMTWRLGQACPRLQAGDAPSLGAGYPRSGTSRFIHTDPSRFMYTTPLRRAAVS 791
             LTS  T        A P L  G A S G    R+               + P   + VS
Sbjct: 2159 -LTSEST--------ANPSL--GTASSAGTKLTRT--------------ISLPTSESLVS 2193

Query: 792  RLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTR 851
               N     +S    S    ++E  +    S G     ++ +D I++   +DG  ++ T 
Sbjct: 2194 FRMNKDPWTVSIPLGSHPTTNTETSIP-VNSAGPPGLSTVASDVIDTP--SDGAESIPTV 2250

Query: 852  SLNRIPDT--ATSRDIIQRGVHD--------------VTVDADSWDDSSSVSSGLSDTLD 895
            S +  PDT   T     ++  H               VT     W  SS++S+  +    
Sbjct: 2251 SFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWM-SSAMSTKPTGASP 2309

Query: 896  NISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEELKKPEEDFDSHG 955
            +I+  +  T +S +  ++  V +   T+  T S    TT +T D  +  K  E   DS  
Sbjct: 2310 SITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSS 2369

Query: 956  DAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGK 1015
             +      +++ +        + AS+S +         S    +  R +  TS  +T   
Sbjct: 2370 SSD----LINTSIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETNTA 2425

Query: 1016 TDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSS--FGFKKPSGV 1073
            T  + +S        GS++  +PS            PP  I     TSS    + +P   
Sbjct: 2426 TSPSVSSNTYSLD-GGSNVGGTPSTL----------PPFTITHPVETSSALLAWSRPVRT 2474

Query: 1074 GSSAMIT--SSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVSSKT 1131
             S+ + T  +SG   TS ++ +  +P   A G  ++ G  T L                 
Sbjct: 2475 FSTMVSTDTASGENPTSSNSVVTSVP---APGTWTSVGSTTDL----------------- 2514

Query: 1132 TLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKIGSGRSSP 1191
                     P+       P    H    S+I+       A A T  L      GS  +S 
Sbjct: 2515 ---------PAMGFLKTSPAGEAHSLLASTIEP------ATAFTPHLSAAVVTGSSATSE 2559

Query: 1192 VTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGS------------- 1238
             ++  T           SES ++  SP++  T  S    +    P S             
Sbjct: 2560 ASLLTT-----------SESKAIHSSPQTPTTPTSGANWETSATPESLLVVTETSDTTLT 2608

Query: 1239 ---------KYPDIASPTFRRLFGAKAGGKS--ASAPNTEGVKSSSVMPSPSTTLARQG- 1286
                      +  +++P  +        G S     P+T  +  ++  P+ S   +    
Sbjct: 2609 SKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSFDST 2668

Query: 1287 ---SLESPSSGT----------GSMGSAGGLSGSSSPLFNKPSDLTTDVI-SLSHSLASS 1332
               ++ S S GT           S G A  L   S+P  + P      V  S  H  ++S
Sbjct: 2669 PLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTS 2728

Query: 1333 PASV---HSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLS-HHGSLSG 1388
            P+ +    + T  G +  A +S+  AG+  +  +   +    ++  +D        S+  
Sbjct: 2729 PSKIVAPRNTTYEGSITVA-LSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMP 2787

Query: 1389 LTTGTHEVQSL-LMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSH 1447
            LTTG+  + S   +R+GS  ST +++     ++LP   L   P    A  E     L + 
Sbjct: 2788 LTTGSQGMASSGGIRSGSTHSTGTKTF----SSLP---LTMNPGEVTAMSEITTNRLTAT 2840

Query: 1448 STGG-----LQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPT-NLSQFNL-----PGPSM 1496
             +       ++ T  +S L++P + SSS +  +       PT  + Q  L       PS+
Sbjct: 2841 QSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSL 2900

Query: 1497 -MRSNSIPAQDSSFDLYDDSQLCGSATSLEERP------------RAIS----HSGSFRD 1539
              +S S+P    S +   DS    +++SL + P            +AIS     S  F +
Sbjct: 2901 DTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTE 2960

Query: 1540 SMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLV 1599
            + E     S++          T + +  SE +            K ++  +  S  + L 
Sbjct: 2961 TPEGSASPSMAGHEPRVPTSGTGDPRYASESMS------YPDPSKASSAMTSTSLASKLT 3014

Query: 1600 AAFEKSLGNMTGRLQSLTMTAEQKESELIE-----------------LRETIEMLKAQNS 1642
              F       +G   S    + +KE+  +                   R+   ++  Q S
Sbjct: 3015 TLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTS 3074

Query: 1643 AAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGNDADSKKKKKKNWV 1702
            A   +    LN     P +L      SS++++     T+ +   +   +++         
Sbjct: 3075 ALTLSPTSTLNMSQEEPPELT-----SSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSS 3129

Query: 1703 NSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHNAGDCGSASMKPS- 1761
             +  +  R S  + +    S    +S   + E TD +L  + K+   A    S    P+ 
Sbjct: 3130 PTEPTARRKSSPETWASSISVPAKTS---LVETTDGTLVTTIKMSSQAAQGNSTWPAPAE 3186

Query: 1762 QSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIE 1821
            ++ S+    +    E+   LK    ++     +IR    +S     +    M      + 
Sbjct: 3187 ETGSSPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVT 3246

Query: 1822 I----LKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNNL 1867
            +    L + +  +      T  PT+ P+E+  +T   S   S   +  NL
Sbjct: 3247 LQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTNL 3296



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 119/549 (21%), Positives = 193/549 (35%), Gaps = 65/549 (11%)

Query: 963  TVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKAS 1022
            T   G+P  P  A       VS + S  +  ++   AP       S L        +  +
Sbjct: 2843 TAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDT 2902

Query: 1023 EKGKAPLKGSSLQRSP-SDAGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITS 1081
            +    P  G SL   P SDA  +S    K P         TS+      S   +    T 
Sbjct: 2903 KSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETP 2962

Query: 1082 SGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVVLHVS--SKTTLQYRSLP 1139
             G+   S +    ++P S   G    A    S          +   S  SK T  + S  
Sbjct: 2963 EGSASPSMAGHEPRVPTSGT-GDPRYASESMSYPDPSKASSAMTSTSLASKLTTLF-STG 3020

Query: 1140 RPSKSSTSGIPGRGGHRSSTSSIDSNVSSK---SAGATTSKLREPTKIGSGRSSPVTVNQ 1196
            + ++S +S  P        TS +    S+    S     S  R+P  +   ++S +T++ 
Sbjct: 3021 QAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSP 3080

Query: 1197 TDKEKEKVAVSDSESVSLSGSPKSSPTSASACGAQGLRQPGSKYPDI-------ASPTFR 1249
            T      + +S  E   L+ S   +    +    Q L    S+ P           PT R
Sbjct: 3081 TST----LNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTAR 3136

Query: 1250 RLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSS 1309
            R    +    S S P       +S++ +   TL     + S ++   S   A      SS
Sbjct: 3137 RKSSPETWASSISVP-----AKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSS 3191

Query: 1310 PLFNKPS--DLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMT 1367
            P    P   +++T +  +S    S    + S T     W             TP  ++  
Sbjct: 3192 PAGTSPGSPEMSTTLKIMSSKEPSISPEIRS-TVRNSPWK------------TP--ETTV 3236

Query: 1368 SLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLR 1427
             + T+ E + L  +  GS  G T+ +H      + TG+   T S +     N L  + + 
Sbjct: 3237 PMETTVEPVTLQSTALGS--GSTSISH------LPTGTTSPTKSPT----ENMLATERVS 3284

Query: 1428 YTPSSRQANQEEGKEW--LRSHSTGGLQD---TGNQSPLVSPSAMSSSAAGKYHFSNLVS 1482
             +PS  +A       W  L S + GG +    T +   L SP+A S +  G+     LVS
Sbjct: 3285 LSPSPPEA-------WTNLYSGTPGGTRQSLATMSSVSLESPTARSITGTGQQSSPELVS 3337

Query: 1483 PTNLSQFNL 1491
             T   +F++
Sbjct: 3338 KTTGMEFSM 3346



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 187/972 (19%), Positives = 327/972 (33%), Gaps = 145/972 (14%)

Query: 482  KPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKE---SLIP-------------SSS 525
            +P K     VT    + T+ I+  IPK SKTT  + E   SL P             S+ 
Sbjct: 4853 EPSKVTSPNVTTSTMEDTT-ISRSIPKSSKTTRTETETTSSLTPKLRETSISQEITSSTE 4911

Query: 526  GIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITME-KASASSCPAPLE 584
                P  ++      +S     S  S  F    G    ++S  I+ E     S+ P   E
Sbjct: 4912 TSTVPYKELTGATTEVSRTDVTSSSSTSF---PGPDQSTVSLDISTETNTRLSTSPIMTE 4968

Query: 585  GRE---AGQASPSGSCTM-TVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSE 640
              E     Q  P G+ +  T       +T    +        S  +  T+   + R   +
Sbjct: 4969 SAEITITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTL---MSRIPQD 5025

Query: 641  NEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGEDPETRRMRT------VKNIADLRQ 694
               T+ PS D  +SP+    S + T    +     ED  +  M +      VK    LR 
Sbjct: 5026 VSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRT 5085

Query: 695  NLEETMSSLRG-TQISHSTLETTFDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQA 753
             LE   SSL   +  S   L T+ DS  T E+     P++ +  T +     +A      
Sbjct: 5086 RLEPVTSSLPNFSSTSDKILATSKDSKDTKEI----FPSINTEETNV-----KANNSGHE 5136

Query: 754  GDAPSLG-AGYPRSGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMS 812
              +P+L  +  P++ T   I T       +T +     S   N+ + + +   +  L  +
Sbjct: 5137 SHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKR-EPTYFLTPRLRET 5195

Query: 813  SEVDVGGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVHD 872
            S      + +D   L                         L+++P T T  ++   GV+ 
Sbjct: 5196 STSQESSFPTDTSFL-------------------------LSKVP-TGTITEVSSTGVNS 5229

Query: 873  VT-VDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKR 931
             + +     D S+      +  +  + T  + T S+  + +    P    +      +  
Sbjct: 5230 SSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTLPLDTS 5289

Query: 932  STTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPED---------PEKAGQKASLS 982
            +T  +                     GG   TV+ G P           P       +  
Sbjct: 5290 TTLSQ---------------------GGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPP 5328

Query: 983  VSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAG 1042
            V +T S    MS+         + TS    P       +S      L  S L  +    G
Sbjct: 5329 VEETSSVSSLMSSPAMTSPSPVSSTSPQSIP-------SSPLPVTALPTSVLVTTTDVLG 5381

Query: 1043 KSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAI 1102
             +S +     P  +   T      +K  +   ++   +++ A    G++  G   +S+ +
Sbjct: 5382 TTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVL 5441

Query: 1103 GGKSNAGRKTSLDGSQNQDDVVLHVSS---KTTLQYRSLPRPSKSSTSGIPGRGGHRSST 1159
                 +     +  +    D  +  S+     T Q ++ P  S S            SST
Sbjct: 5442 ADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSST 5501

Query: 1160 SSIDSNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPK 1219
            +  ++  S    GA T   R  T+I S R+S   ++  D+      +S      L  SP 
Sbjct: 5502 TETNTAFSYVPTGAITQASR--TEISSSRTS---ISDLDRPTIAPDISTGMITRLFTSPI 5556

Query: 1220 SSPTSASACGAQGLRQPGSKYPDIASPTFRRLF-GAKAGGKSASAPNTEGVKSSSVMPSP 1278
             + ++      Q      +    +   T   LF G      S   P++E     S  P  
Sbjct: 5557 MTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGD 5616

Query: 1279 STTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHS 1338
             + +     +E  SSG   M          SP    PS +++   +   S+ SSP  V +
Sbjct: 5617 VSWMTTP-PVEETSSGFSLM----------SPSMTSPSPVSS---TSPESIPSSPLPVTA 5662

Query: 1339 FTSGGLVWAANM--------SSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLT 1390
              +  LV   N+         +SS  +  +P+ + +T+   ++ +  +  S H + +   
Sbjct: 5663 LLTSVLVTTTNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNTAVAN 5722

Query: 1391 TGT----HEVQS 1398
             GT    HE QS
Sbjct: 5723 VGTSISGHESQS 5734



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 138/684 (20%), Positives = 234/684 (34%), Gaps = 120/684 (17%)

Query: 873  VTVDADSWDDS--------SSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQL 924
            V++   +W +S        S ++  L D    + T     TS +SS  +  +     T++
Sbjct: 3992 VSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGSTAITKGPRTEI 4051

Query: 925  ----RTDSEKRSTTDETWDSPEELKKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKAS 980
                R  S   + +  + DSP E      +F +  ++GG    + +  P     +    +
Sbjct: 4052 TSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPPGATSLSAP--T 4109

Query: 981  LSVSQTGSWRRGMSAQGGAPSRQKAGTSALKTPGKTD-------DAKASEKGKAPLKGSS 1033
            L  S T SW     A     +  +  T   K P  T        +  +S     P+  ++
Sbjct: 4110 LDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATT 4169

Query: 1034 LQRSPSDAGKSSGDEGKK--PP---------SGIGRSTATSSF----GFKKPSGVGSSA- 1077
               SPS+   +S        PP         SG+G++T  S      G   P  + S+A 
Sbjct: 4170 ---SPSNILLTSQGHSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTAG 4226

Query: 1078 ---------------------MITSSGATITSGSATLGKIPKSAAIGG------KSNAGR 1110
                                  +T+  AT +  S   G    S A           +   
Sbjct: 4227 EALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDITS 4286

Query: 1111 KTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKS 1170
             TS+ GS    ++    S    LQ RS  + + S+T            TS++ ++VSS  
Sbjct: 4287 STSVFGSSETTEIETVSSVNQGLQERSTSQVASSATE-----------TSTVITHVSSGD 4335

Query: 1171 AGATTSKLREPTKIGSGRSSP---VTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSASA 1227
            A    +K +     G+  SSP   +T   T  +     VS + S SL  +  S  T  + 
Sbjct: 4336 ATTHVTKTQATFSSGTSISSPHQFITSTNTFTD-----VSTNPSTSLIMTESSGVTITTQ 4390

Query: 1228 CGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGS 1287
             G  G    G    D ++  +                 T    +   M S  TTL  +G 
Sbjct: 4391 TGPTGAATQGPYLLDTSTMPY--------------LTETPLAVTPDFMQSEKTTLISKGP 4436

Query: 1288 LESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWA 1347
             +   +   S+        S +P         T  +   H+  SSP S  S  + GLV  
Sbjct: 4437 KDVSWTSPPSVAET-SYPSSLTPFLVTTIPPATSTLQGQHT--SSPVSATSVLTSGLVKT 4493

Query: 1348 ANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEVQSLLMRTGSVR 1407
             +M ++           SM  +  S ++++ P +   +    TT    +   + +  +  
Sbjct: 4494 TDMLNT-----------SMEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNM 4542

Query: 1408 STLSESMQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGNQSPLVSPSAM 1467
             T S +  L  +TLP      T +S         + L S S  G + T      +     
Sbjct: 4543 GTASSAHVL-HSTLPVSSEPSTATSPMVPASSMGDALASISIPGSETTD-----IEGEPT 4596

Query: 1468 SSSAAGKYHFSNLVSPTNLSQFNL 1491
            SS  AG+   S L    + ++ N+
Sbjct: 4597 SSLTAGRKENSTLQEMNSTTESNI 4620



 Score = 37.7 bits (86), Expect = 0.13
 Identities = 239/1173 (20%), Positives = 404/1173 (34%), Gaps = 173/1173 (14%)

Query: 300  QSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSP 359
            QSS          S+AG   AS +P  + S+   S S  ++  +T +  T   SS   + 
Sbjct: 2763 QSSENSETTALVDSSAGLERASVMPLTTGSQGMAS-SGGIRSGSTHSTGTKTFSSLPLTM 2821

Query: 360  TPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDA--- 416
             P        ++    TA           K  +A + L  P   SS PS           
Sbjct: 2822 NPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPP 2881

Query: 417  ------------FSESGEMEGFNSGLNSGG-STNSSPKVSPKLAPPKAGSKNLSNKKSLL 463
                        FSE   ++  ++ L + G S N+ P      A     S +LS      
Sbjct: 2882 TWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTA-----SSSLS------ 2930

Query: 464  QPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKKTSKIASLIPKGSKTTA-AKKESLIP 522
               +  EKN     + + K +     Q T              P+GS + + A  E  +P
Sbjct: 2931 ---KSPEKNPRARMMTSTKAISASSFQSTGFTET---------PEGSASPSMAGHEPRVP 2978

Query: 523  SS-SGIPKPGSKVPT------VKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKAS 575
            +S +G P+  S+  +          ++  S ASK +  F T + + S S S PI++    
Sbjct: 2979 TSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEK 3038

Query: 576  ASSCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIY 635
             +S  +P               T + ++ +    G    + P    H   +  T++P   
Sbjct: 3039 ETSFLSP---------------TASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTST 3083

Query: 636  RAHSENEGTALPSA------DSCTSPTK-MDLSYSKTAKQCLEEISGEDPETRRMRTVKN 688
               S+ E   L S+      +  T+ T+ +  + S+T    L   S  +P  R       
Sbjct: 3084 LNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTAR------- 3136

Query: 689  IADLRQNLEETMSSLRGTQISHSTLETTFDSTVTT-EVNGRTIPNLTSRPTPMTWRLGQA 747
                R++  ET +S        S +ETT  + VTT +++ +     ++ P P        
Sbjct: 3137 ----RKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAE------ 3186

Query: 748  CPRLQAGDAPS-LGAGYPRSGTSRFIHT--DPS----------RFMYTTPLRRAAVSRLG 794
                + G +P+    G P   T+  I +  +PS             + TP     V    
Sbjct: 3187 ----ETGSSPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTP--ETTVPMET 3240

Query: 795  NMSQIDMSEKA-SSDLDMSSEVDVGGYMSDGDILGKSLRTDDIN-SGYMTDGGLNLYTRS 852
             +  + +   A  S     S +  G            L T+ ++ S    +   NLY+ +
Sbjct: 3241 TVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTNLYSGT 3300

Query: 853  ---LNRIPDTATSRDIIQRGVHDVT-VDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSV 908
                 +   T +S  +       +T     S  +  S ++G+  ++ + ST      + V
Sbjct: 3301 PGGTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHV 3360

Query: 909  --SSYSNI---TVPSRKNTQLRTDSEKRSTTDETWDSPEEL-------------KKPEED 950
              S+ SNI    V S  +    TD  K  T  ETW S   +             ++    
Sbjct: 3361 SLSTSSNILEDPVTSPNSVSSLTDKSKHKT--ETWVSTTAIPSTVLNNKIMAAEQQTSRS 3418

Query: 951  FDSHGDAGGKWKTVSSG----LPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQKAG 1006
             D    +   W   +SG    L   P+        S +QT S    +S   G       G
Sbjct: 3419 VDEAYSSTSSWSDQTSGSDITLGASPDVTNTLYITSTAQTTSL---VSLPSG-----DQG 3470

Query: 1007 TSALKTP--GKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSS 1064
             ++L  P  GKT  A +     +P  G    R+   A KS         S        S 
Sbjct: 3471 ITSLTNPSGGKTSSASSV---TSPSIGLETLRANVSAVKSDIAPTAGHLSQTSSPAEVSI 3527

Query: 1065 FGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDVV 1124
                     G S  IT+ G    S +    ++  S      +   R TS +         
Sbjct: 3528 LDVTTAPTPGISTTITTMGTNSISTTTPNPEVGMSTMDSTPATERRTTSTEHPSTWSSTA 3587

Query: 1125 LHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLREPTKI 1184
               S   T         S    +  PG      +TS + S+    S      ++   T I
Sbjct: 3588 ASDSWTVT------DMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTPHGRI---TVI 3638

Query: 1185 GSGRSSPVTVNQTDKEKEKVAVSDSE-SVSLSGSPKSSPTSASACGAQGLRQPGSKYPDI 1243
            G+   +P     +D    K   S SE ++S S +  S+P S  +     +++     PDI
Sbjct: 3639 GTSLVTP----SSDASAVKTETSTSERTLSPSDTTASTPISTFS----RVQRMSISVPDI 3690

Query: 1244 ASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLARQGSLESPSSGTGSMGSAGG 1303
             S ++      +A     S  +T+   + +   +P +T     SL +    TG   S+  
Sbjct: 3691 LSTSWTP-SSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFD-SLSTLDWDTGRSLSSAT 3748

Query: 1304 LSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGLVWAANMSSSSAGSKDTPSY 1363
             + S+      P +LT + + +S + +  P S+   TS   V  A M+ SS  +   P  
Sbjct: 3749 ATTSAPQGATTPQELTLETM-ISPATSQLPFSIGHITSA--VTPAAMARSSGVTFSRPDP 3805

Query: 1364 QSMTSLHTSSESIDLPLSHHGSLSGLTTGTHEV 1396
             S  +  TS++      +H G +      T +V
Sbjct: 3806 TSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDV 3838


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.123    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,511,585
Number of Sequences: 37866
Number of extensions: 4671158
Number of successful extensions: 32727
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 1242
Number of HSP's that attempted gapping in prelim test: 22827
Number of HSP's gapped (non-prelim): 8870
length of query: 2363
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2244
effective length of database: 13,741,464
effective search space: 30835845216
effective search space used: 30835845216
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.