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Search of human proteins with 24797106
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24797106 UBX domain containing 8 [Homo sapiens]
(445 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24797106 UBX domain containing 8 [Homo sapiens] 904 0.0
gi|5901948 FAS-associated factor 1 [Homo sapiens] 127 2e-29
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 58 2e-08
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 58 2e-08
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 58 2e-08
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 58 2e-08
gi|92859701 myosin VI [Homo sapiens] 56 8e-08
gi|148746195 trichohyalin [Homo sapiens] 54 3e-07
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 53 6e-07
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 52 1e-06
gi|56549694 enabled homolog isoform a [Homo sapiens] 51 2e-06
gi|39930375 enabled homolog isoform b [Homo sapiens] 51 2e-06
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 49 7e-06
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 49 7e-06
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 49 9e-06
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 49 9e-06
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 49 9e-06
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 49 9e-06
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 49 9e-06
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 49 1e-05
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 48 2e-05
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 48 2e-05
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 48 2e-05
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa... 48 2e-05
gi|52426743 cisplatin resistance-associated overexpressed protei... 47 3e-05
gi|19923485 cisplatin resistance-associated overexpressed protei... 47 3e-05
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 47 3e-05
gi|21264343 scaffold attachment factor B [Homo sapiens] 47 5e-05
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 46 6e-05
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 46 6e-05
>gi|24797106 UBX domain containing 8 [Homo sapiens]
Length = 445
Score = 904 bits (2337), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 1 MAAPEERDLTQEQTEKLLQFQDLTGIESMDQCRHTLEQHNWNIEAAVQDRLNEQEGVPSV 60
MAAPEERDLTQEQTEKLLQFQDLTGIESMDQCRHTLEQHNWNIEAAVQDRLNEQEGVPSV
Sbjct: 1 MAAPEERDLTQEQTEKLLQFQDLTGIESMDQCRHTLEQHNWNIEAAVQDRLNEQEGVPSV 60
Query: 61 FNPPPSRPLQVNTADHRIYSYVVSRPQPRGLLGWGYYLIMLPFRFTYYTILDIFRFALRF 120
FNPPPSRPLQVNTADHRIYSYVVSRPQPRGLLGWGYYLIMLPFRFTYYTILDIFRFALRF
Sbjct: 61 FNPPPSRPLQVNTADHRIYSYVVSRPQPRGLLGWGYYLIMLPFRFTYYTILDIFRFALRF 120
Query: 121 IRPDPRSRVTDPVGDIVSFMHSFEEKYGRAHPVFYQGTYSQALNDAKRELRFLLVYLHGD 180
IRPDPRSRVTDPVGDIVSFMHSFEEKYGRAHPVFYQGTYSQALNDAKRELRFLLVYLHGD
Sbjct: 121 IRPDPRSRVTDPVGDIVSFMHSFEEKYGRAHPVFYQGTYSQALNDAKRELRFLLVYLHGD 180
Query: 181 DHQDSDEFCRNTLCAPEVISLINTRMLFWACSTNKPEGYRVSQALRENTYPFLAMIMLKD 240
DHQDSDEFCRNTLCAPEVISLINTRMLFWACSTNKPEGYRVSQALRENTYPFLAMIMLKD
Sbjct: 181 DHQDSDEFCRNTLCAPEVISLINTRMLFWACSTNKPEGYRVSQALRENTYPFLAMIMLKD 240
Query: 241 RRMTVVGRLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLAS 300
RRMTVVGRLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLAS
Sbjct: 241 RRMTVVGRLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLAS 300
Query: 301 LRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPE 360
LRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPE
Sbjct: 301 LRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPE 360
Query: 361 SVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFSLKESPEKFQIEANFPRRVLPCIPSEEW 420
SVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFSLKESPEKFQIEANFPRRVLPCIPSEEW
Sbjct: 361 SVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFSLKESPEKFQIEANFPRRVLPCIPSEEW 420
Query: 421 PNPPTLQEAGLSHTEVLFVQDLTDE 445
PNPPTLQEAGLSHTEVLFVQDLTDE
Sbjct: 421 PNPPTLQEAGLSHTEVLFVQDLTDE 445
>gi|5901948 FAS-associated factor 1 [Homo sapiens]
Length = 650
Score = 127 bits (320), Expect = 2e-29
Identities = 97/352 (27%), Positives = 169/352 (48%), Gaps = 35/352 (9%)
Query: 112 DIFRFALRFIRPDPRS-RVTDPVGD-IVSFMHSFEEKYGRAHPVFYQGTYSQALNDA--- 166
++F A +R P + GD ++ F F +YG HPVF+ G+ A +A
Sbjct: 308 EVFGMASSALRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYV 367
Query: 167 -KRELRFLLVYLHGDDHQDSDEFCRNTLCAPEVISLINTRMLFWACSTNKPE-------- 217
R+ + L +YLH D+ ++ FC LCA ++S ++ + WA K
Sbjct: 368 KARDRKLLAIYLHHDESVLTNVFCSQMLCAESIVSYLSQNFITWAWDLTKDSNRARFLTM 427
Query: 218 -----GYRVSQALRE---NTYPFLAMIMLKDRRMTVVGRLEGLIQPDDLINQLTFIMDAN 269
G V+Q +R + +P +IM K V+ ++G D+L+ +L M+
Sbjct: 428 CNRHFGSVVAQTIRTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRLMAAMEIF 487
Query: 270 QTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQK 329
+ + +ER + ++++QDEAY SL AD R KRE ER+ ++ ++Q +
Sbjct: 488 TAQQQEDIKDEDEREARENVKREQDEAYRLSLEAD----RAKREAHEREMAEQFRLEQIR 543
Query: 330 LAEERRRQNLQEEKERKLECLPPEPSPDDPESV-KIIFKLPNDSRVERRFHFSQSLTVIH 388
+E R+ ++ E + LPPEP ++ E V K+ + P+ +ERRF S L ++
Sbjct: 544 KEQEEEREAIRLSLE---QALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVF 600
Query: 389 DFLFSLKESPEKFQIEANFPRRVLPCIPSEEWPNPPTLQEAGLSHTEVLFVQ 440
DF+ S +++++ + FPRR + + PN +L E L E LF++
Sbjct: 601 DFVASKGFPWDEYKLLSTFPRRDVTQLD----PN-KSLLEVKLFPQETLFLE 647
Score = 39.3 bits (90), Expect = 0.007
Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 26/107 (24%)
Query: 17 LLQFQDLTGIESMDQCRHTLEQHNWNIEAAVQDRLNEQEGV-----------PSVFNP-- 63
L FQ TGIE++D+ LEQ+NW++ AA+ + ++ G+ FNP
Sbjct: 11 LADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSEYGGETIPGPAFNPAS 70
Query: 64 -PPSRPLQVNTADHR--IYSYVVSRPQPRGLLGWGYYLIMLPFRFTY 107
P S P +++ R + S + QPR ML FR Y
Sbjct: 71 HPASAPTSSSSSAFRPVMPSRQIVERQPR----------MLDFRVEY 107
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 58.2 bits (139), Expect = 2e-08
Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 14/106 (13%)
Query: 255 PDDLINQLTFIMDANQTYLVSERLE--------REERNQTQVLRQQQDEAYLASLRADQE 306
P + QL + A L ER E EER + + LR+QQ+E LR QE
Sbjct: 713 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI----LRRQQE 768
Query: 307 KERKKREERERKRRKEEEVQQQKLAEE--RRRQNLQEEKERKLECL 350
+ERK+REE E RRK+EE +++ +E RRQ +EE++++ E L
Sbjct: 769 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL 814
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/76 (35%), Positives = 48/76 (63%), Gaps = 4/76 (5%)
Query: 273 LVSERLEREE-RNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLA 331
L R E EE R Q ++LR+Q++E A+ A +E+E ++R E R R +EE + +
Sbjct: 817 LEERRREEEERRKQEELLRKQEEE---AAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 873
Query: 332 EERRRQNLQEEKERKL 347
EER+R+ L+ +++++L
Sbjct: 874 EERKRKELEVQRQKEL 889
Score = 43.9 bits (102), Expect = 3e-04
Identities = 24/69 (34%), Positives = 44/69 (63%), Gaps = 5/69 (7%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
ER+ R + ++ R++Q+EA LR +E+E R +RE + R+++E ++L EERRR+
Sbjct: 770 ERKRREEEELARRKQEEA----LRRQREQEIALRRQREEEERQQQEEALRRL-EERRREE 824
Query: 339 LQEEKERKL 347
+ K+ +L
Sbjct: 825 EERRKQEEL 833
Score = 42.7 bits (99), Expect = 7e-04
Identities = 28/74 (37%), Positives = 46/74 (62%), Gaps = 6/74 (8%)
Query: 276 ERLEREERNQTQVLR-QQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
+R E R Q ++LR QQ++E R ++E R+K+EE R++R++E +++ EE
Sbjct: 750 KRQEELRRQQEEILRRQQEEE---RKRREEEELARRKQEEALRRQREQEIALRRQREEEE 806
Query: 335 RRQNLQEEKERKLE 348
R+Q QEE R+LE
Sbjct: 807 RQQ--QEEALRRLE 818
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
+R E E + Q + LR+ ++ R QE+ +K+EE K +EEE Q++L E R
Sbjct: 801 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 860
Query: 336 RQNLQ------EEKERK 346
R + EE+ERK
Sbjct: 861 RMEEEAARLRHEEEERK 877
Score = 40.0 bits (92), Expect = 0.004
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
E L R+ + + RQ+++E A + E ++REE E RRK+EE+ +++ E +
Sbjct: 786 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE--RRKQEELLRKQEEEAAK 843
Query: 336 RQNLQEEKERKLE 348
+EE +R+LE
Sbjct: 844 WAREEEEAQRRLE 856
Score = 39.3 bits (90), Expect = 0.007
Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 6/75 (8%)
Query: 274 VSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEE 333
++ R +REE RQQQ+EA L L + +E ++R++ E R++EEE + EE
Sbjct: 796 IALRRQREEEE-----RQQQEEA-LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE 849
Query: 334 RRRQNLQEEKERKLE 348
++ L+E + R E
Sbjct: 850 EAQRRLEENRLRMEE 864
Score = 38.5 bits (88), Expect = 0.012
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 21/100 (21%)
Query: 277 RLEREERNQTQVLRQQQDEAYL---------------------ASLRADQEKERKKREER 315
R E E R Q ++LR+Q++EA + R E+E +KR+E
Sbjct: 822 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 881
Query: 316 ERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPS 355
E +R+KE Q+Q+ E RR Q+++++ + P S
Sbjct: 882 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 921
Score = 32.0 bits (71), Expect = 1.2
Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 24/93 (25%)
Query: 276 ERLEREERNQTQVLR---QQQDEAYLASLRADQEKE---------------------RKK 311
+ L R+ + Q + LR QQQ + LA ++ +K
Sbjct: 887 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 946
Query: 312 REERERKRRKEEEVQQQKLAEERRRQNLQEEKE 344
EERER+ R+E+ QQ++L + ++Q Q++++
Sbjct: 947 EEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
Score = 28.9 bits (63), Expect = 9.9
Identities = 17/83 (20%), Positives = 38/83 (45%), Gaps = 20/83 (24%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKK--------------------REER 315
++LE E Q + +++Q + +L+ Q+++++K ++E
Sbjct: 944 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEE 1003
Query: 316 ERKRRKEEEVQQQKLAEERRRQN 338
R+ +K+++ QQQ R R N
Sbjct: 1004 ARQMQKQQQQQQQHQQPNRARNN 1026
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 58.2 bits (139), Expect = 2e-08
Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 14/106 (13%)
Query: 255 PDDLINQLTFIMDANQTYLVSERLE--------REERNQTQVLRQQQDEAYLASLRADQE 306
P + QL + A L ER E EER + + LR+QQ+E LR QE
Sbjct: 740 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI----LRRQQE 795
Query: 307 KERKKREERERKRRKEEEVQQQKLAEE--RRRQNLQEEKERKLECL 350
+ERK+REE E RRK+EE +++ +E RRQ +EE++++ E L
Sbjct: 796 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL 841
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/76 (35%), Positives = 48/76 (63%), Gaps = 4/76 (5%)
Query: 273 LVSERLEREE-RNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLA 331
L R E EE R Q ++LR+Q++E A+ A +E+E ++R E R R +EE + +
Sbjct: 844 LEERRREEEERRKQEELLRKQEEE---AAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 900
Query: 332 EERRRQNLQEEKERKL 347
EER+R+ L+ +++++L
Sbjct: 901 EERKRKELEVQRQKEL 916
Score = 43.9 bits (102), Expect = 3e-04
Identities = 24/69 (34%), Positives = 44/69 (63%), Gaps = 5/69 (7%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
ER+ R + ++ R++Q+EA LR +E+E R +RE + R+++E ++L EERRR+
Sbjct: 797 ERKRREEEELARRKQEEA----LRRQREQEIALRRQREEEERQQQEEALRRL-EERRREE 851
Query: 339 LQEEKERKL 347
+ K+ +L
Sbjct: 852 EERRKQEEL 860
Score = 42.7 bits (99), Expect = 7e-04
Identities = 28/74 (37%), Positives = 46/74 (62%), Gaps = 6/74 (8%)
Query: 276 ERLEREERNQTQVLR-QQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
+R E R Q ++LR QQ++E R ++E R+K+EE R++R++E +++ EE
Sbjct: 777 KRQEELRRQQEEILRRQQEEE---RKRREEEELARRKQEEALRRQREQEIALRRQREEEE 833
Query: 335 RRQNLQEEKERKLE 348
R+Q QEE R+LE
Sbjct: 834 RQQ--QEEALRRLE 845
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
+R E E + Q + LR+ ++ R QE+ +K+EE K +EEE Q++L E R
Sbjct: 828 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 887
Query: 336 RQNLQ------EEKERK 346
R + EE+ERK
Sbjct: 888 RMEEEAARLRHEEEERK 904
Score = 40.0 bits (92), Expect = 0.004
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
E L R+ + + RQ+++E A + E ++REE E RRK+EE+ +++ E +
Sbjct: 813 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE--RRKQEELLRKQEEEAAK 870
Query: 336 RQNLQEEKERKLE 348
+EE +R+LE
Sbjct: 871 WAREEEEAQRRLE 883
Score = 39.3 bits (90), Expect = 0.007
Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 6/75 (8%)
Query: 274 VSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEE 333
++ R +REE RQQQ+EA L L + +E ++R++ E R++EEE + EE
Sbjct: 823 IALRRQREEEE-----RQQQEEA-LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE 876
Query: 334 RRRQNLQEEKERKLE 348
++ L+E + R E
Sbjct: 877 EAQRRLEENRLRMEE 891
Score = 38.5 bits (88), Expect = 0.012
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 21/100 (21%)
Query: 277 RLEREERNQTQVLRQQQDEAYL---------------------ASLRADQEKERKKREER 315
R E E R Q ++LR+Q++EA + R E+E +KR+E
Sbjct: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 908
Query: 316 ERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPS 355
E +R+KE Q+Q+ E RR Q+++++ + P S
Sbjct: 909 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 948
Score = 32.0 bits (71), Expect = 1.2
Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 24/93 (25%)
Query: 276 ERLEREERNQTQVLR---QQQDEAYLASLRADQEKE---------------------RKK 311
+ L R+ + Q + LR QQQ + LA ++ +K
Sbjct: 914 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 973
Query: 312 REERERKRRKEEEVQQQKLAEERRRQNLQEEKE 344
EERER+ R+E+ QQ++L + ++Q Q++++
Sbjct: 974 EEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
Score = 28.9 bits (63), Expect = 9.9
Identities = 17/83 (20%), Positives = 38/83 (45%), Gaps = 20/83 (24%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKK--------------------REER 315
++LE E Q + +++Q + +L+ Q+++++K ++E
Sbjct: 971 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEE 1030
Query: 316 ERKRRKEEEVQQQKLAEERRRQN 338
R+ +K+++ QQQ R R N
Sbjct: 1031 ARQMQKQQQQQQQHQQPNRARNN 1053
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 58.2 bits (139), Expect = 2e-08
Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 14/106 (13%)
Query: 255 PDDLINQLTFIMDANQTYLVSERLE--------REERNQTQVLRQQQDEAYLASLRADQE 306
P + QL + A L ER E EER + + LR+QQ+E LR QE
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI----LRRQQE 774
Query: 307 KERKKREERERKRRKEEEVQQQKLAEE--RRRQNLQEEKERKLECL 350
+ERK+REE E RRK+EE +++ +E RRQ +EE++++ E L
Sbjct: 775 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL 820
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/76 (35%), Positives = 48/76 (63%), Gaps = 4/76 (5%)
Query: 273 LVSERLEREE-RNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLA 331
L R E EE R Q ++LR+Q++E A+ A +E+E ++R E R R +EE + +
Sbjct: 823 LEERRREEEERRKQEELLRKQEEE---AAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 879
Query: 332 EERRRQNLQEEKERKL 347
EER+R+ L+ +++++L
Sbjct: 880 EERKRKELEVQRQKEL 895
Score = 43.9 bits (102), Expect = 3e-04
Identities = 24/69 (34%), Positives = 44/69 (63%), Gaps = 5/69 (7%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
ER+ R + ++ R++Q+EA LR +E+E R +RE + R+++E ++L EERRR+
Sbjct: 776 ERKRREEEELARRKQEEA----LRRQREQEIALRRQREEEERQQQEEALRRL-EERRREE 830
Query: 339 LQEEKERKL 347
+ K+ +L
Sbjct: 831 EERRKQEEL 839
Score = 42.7 bits (99), Expect = 7e-04
Identities = 28/74 (37%), Positives = 46/74 (62%), Gaps = 6/74 (8%)
Query: 276 ERLEREERNQTQVLR-QQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
+R E R Q ++LR QQ++E R ++E R+K+EE R++R++E +++ EE
Sbjct: 756 KRQEELRRQQEEILRRQQEEE---RKRREEEELARRKQEEALRRQREQEIALRRQREEEE 812
Query: 335 RRQNLQEEKERKLE 348
R+Q QEE R+LE
Sbjct: 813 RQQ--QEEALRRLE 824
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
+R E E + Q + LR+ ++ R QE+ +K+EE K +EEE Q++L E R
Sbjct: 807 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 866
Query: 336 RQNLQ------EEKERK 346
R + EE+ERK
Sbjct: 867 RMEEEAARLRHEEEERK 883
Score = 40.0 bits (92), Expect = 0.004
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
E L R+ + + RQ+++E A + E ++REE E RRK+EE+ +++ E +
Sbjct: 792 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE--RRKQEELLRKQEEEAAK 849
Query: 336 RQNLQEEKERKLE 348
+EE +R+LE
Sbjct: 850 WAREEEEAQRRLE 862
Score = 39.3 bits (90), Expect = 0.007
Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 6/75 (8%)
Query: 274 VSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEE 333
++ R +REE RQQQ+EA L L + +E ++R++ E R++EEE + EE
Sbjct: 802 IALRRQREEEE-----RQQQEEA-LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE 855
Query: 334 RRRQNLQEEKERKLE 348
++ L+E + R E
Sbjct: 856 EAQRRLEENRLRMEE 870
Score = 38.5 bits (88), Expect = 0.012
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 21/100 (21%)
Query: 277 RLEREERNQTQVLRQQQDEAYL---------------------ASLRADQEKERKKREER 315
R E E R Q ++LR+Q++EA + R E+E +KR+E
Sbjct: 828 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
Query: 316 ERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPS 355
E +R+KE Q+Q+ E RR Q+++++ + P S
Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
Score = 32.0 bits (71), Expect = 1.2
Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 24/93 (25%)
Query: 276 ERLEREERNQTQVLR---QQQDEAYLASLRADQEKE---------------------RKK 311
+ L R+ + Q + LR QQQ + LA ++ +K
Sbjct: 893 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952
Query: 312 REERERKRRKEEEVQQQKLAEERRRQNLQEEKE 344
EERER+ R+E+ QQ++L + ++Q Q++++
Sbjct: 953 EEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
Score = 28.9 bits (63), Expect = 9.9
Identities = 17/83 (20%), Positives = 38/83 (45%), Gaps = 20/83 (24%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKK--------------------REER 315
++LE E Q + +++Q + +L+ Q+++++K ++E
Sbjct: 950 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEE 1009
Query: 316 ERKRRKEEEVQQQKLAEERRRQN 338
R+ +K+++ QQQ R R N
Sbjct: 1010 ARQMQKQQQQQQQHQQPNRARNN 1032
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 58.2 bits (139), Expect = 2e-08
Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 14/106 (13%)
Query: 255 PDDLINQLTFIMDANQTYLVSERLE--------REERNQTQVLRQQQDEAYLASLRADQE 306
P + QL + A L ER E EER + + LR+QQ+E LR QE
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI----LRRQQE 774
Query: 307 KERKKREERERKRRKEEEVQQQKLAEE--RRRQNLQEEKERKLECL 350
+ERK+REE E RRK+EE +++ +E RRQ +EE++++ E L
Sbjct: 775 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL 820
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/76 (35%), Positives = 48/76 (63%), Gaps = 4/76 (5%)
Query: 273 LVSERLEREE-RNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLA 331
L R E EE R Q ++LR+Q++E A+ A +E+E ++R E R R +EE + +
Sbjct: 823 LEERRREEEERRKQEELLRKQEEE---AAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 879
Query: 332 EERRRQNLQEEKERKL 347
EER+R+ L+ +++++L
Sbjct: 880 EERKRKELEVQRQKEL 895
Score = 43.9 bits (102), Expect = 3e-04
Identities = 24/69 (34%), Positives = 44/69 (63%), Gaps = 5/69 (7%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
ER+ R + ++ R++Q+EA LR +E+E R +RE + R+++E ++L EERRR+
Sbjct: 776 ERKRREEEELARRKQEEA----LRRQREQEIALRRQREEEERQQQEEALRRL-EERRREE 830
Query: 339 LQEEKERKL 347
+ K+ +L
Sbjct: 831 EERRKQEEL 839
Score = 42.7 bits (99), Expect = 7e-04
Identities = 28/74 (37%), Positives = 46/74 (62%), Gaps = 6/74 (8%)
Query: 276 ERLEREERNQTQVLR-QQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
+R E R Q ++LR QQ++E R ++E R+K+EE R++R++E +++ EE
Sbjct: 756 KRQEELRRQQEEILRRQQEEE---RKRREEEELARRKQEEALRRQREQEIALRRQREEEE 812
Query: 335 RRQNLQEEKERKLE 348
R+Q QEE R+LE
Sbjct: 813 RQQ--QEEALRRLE 824
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
+R E E + Q + LR+ ++ R QE+ +K+EE K +EEE Q++L E R
Sbjct: 807 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 866
Query: 336 RQNLQ------EEKERK 346
R + EE+ERK
Sbjct: 867 RMEEEAARLRHEEEERK 883
Score = 40.0 bits (92), Expect = 0.004
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
E L R+ + + RQ+++E A + E ++REE E RRK+EE+ +++ E +
Sbjct: 792 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEE--RRKQEELLRKQEEEAAK 849
Query: 336 RQNLQEEKERKLE 348
+EE +R+LE
Sbjct: 850 WAREEEEAQRRLE 862
Score = 39.3 bits (90), Expect = 0.007
Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 6/75 (8%)
Query: 274 VSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEE 333
++ R +REE RQQQ+EA L L + +E ++R++ E R++EEE + EE
Sbjct: 802 IALRRQREEEE-----RQQQEEA-LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE 855
Query: 334 RRRQNLQEEKERKLE 348
++ L+E + R E
Sbjct: 856 EAQRRLEENRLRMEE 870
Score = 38.5 bits (88), Expect = 0.012
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 21/100 (21%)
Query: 277 RLEREERNQTQVLRQQQDEAYL---------------------ASLRADQEKERKKREER 315
R E E R Q ++LR+Q++EA + R E+E +KR+E
Sbjct: 828 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
Query: 316 ERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPS 355
E +R+KE Q+Q+ E RR Q+++++ + P S
Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS 927
Score = 32.0 bits (71), Expect = 1.2
Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 24/93 (25%)
Query: 276 ERLEREERNQTQVLR---QQQDEAYLASLRADQEKE---------------------RKK 311
+ L R+ + Q + LR QQQ + LA ++ +K
Sbjct: 893 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952
Query: 312 REERERKRRKEEEVQQQKLAEERRRQNLQEEKE 344
EERER+ R+E+ QQ++L + ++Q Q++++
Sbjct: 953 EEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
Score = 28.9 bits (63), Expect = 9.9
Identities = 17/83 (20%), Positives = 38/83 (45%), Gaps = 20/83 (24%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKK--------------------REER 315
++LE E Q + +++Q + +L+ Q+++++K ++E
Sbjct: 950 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEE 1009
Query: 316 ERKRRKEEEVQQQKLAEERRRQN 338
R+ +K+++ QQQ R R N
Sbjct: 1010 ARQMQKQQQQQQQHQQPNRARNN 1032
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 55.8 bits (133), Expect = 8e-08
Identities = 31/61 (50%), Positives = 45/61 (73%), Gaps = 3/61 (4%)
Query: 287 QVLRQQQDEAY-LASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKER 345
Q +QQ++EA L ++ + EKERK+REE E++RRKEEE ++ KL E +R+ QEE+ER
Sbjct: 914 QKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRK--QEEEER 971
Query: 346 K 346
K
Sbjct: 972 K 972
Score = 42.7 bits (99), Expect = 7e-04
Identities = 20/106 (18%), Positives = 65/106 (61%), Gaps = 4/106 (3%)
Query: 244 TVVGRLEGLIQPDDLIN-QLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLR 302
T++ +++ + + I + ++ +++ L + + ++++ + + LR+ Q+E R
Sbjct: 880 TLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKR 939
Query: 303 ADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
+++++R+++EE ER+ + E E ++++ EER++ +E+ E++++
Sbjct: 940 REEDEKRRRKEEEERRMKLEMEAKRKQEEEERKK---REDDEKRIQ 982
Score = 42.4 bits (98), Expect = 9e-04
Identities = 26/73 (35%), Positives = 41/73 (56%), Gaps = 15/73 (20%)
Query: 279 EREERNQTQVLRQQQDEAYLASL-----RADQEKERKKREERERK----------RRKEE 323
ER+ R + + R++++E L R +E+ERKKRE+ E++ R+KEE
Sbjct: 936 ERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEE 995
Query: 324 EVQQQKLAEERRR 336
E QQQ + E+ RR
Sbjct: 996 ESQQQAVLEQERR 1008
Score = 38.5 bits (88), Expect = 0.012
Identities = 19/80 (23%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 267 DANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQ 326
+A + + E +E+E + + + ++++ E ++ + E +RK+ EE ERK+R+++E +
Sbjct: 922 EAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEE-ERKKREDDEKR 980
Query: 327 QQKLAEERRRQNLQEEKERK 346
Q E + + +EE +++
Sbjct: 981 IQAEVEAQLARQKEEESQQQ 1000
Score = 33.5 bits (75), Expect = 0.40
Identities = 25/98 (25%), Positives = 53/98 (54%), Gaps = 12/98 (12%)
Query: 275 SERLER-EERNQTQVLRQQQDEAYLASLRADQEKERK-------KREERERKRRKEEEVQ 326
+ERL R +E + + R+++DE R +E+ER+ KR++ E +R+K E+ +
Sbjct: 923 AERLRRIQEEMEKERKRREEDE----KRRRKEEEERRMKLEMEAKRKQEEEERKKREDDE 978
Query: 327 QQKLAEERRRQNLQEEKERKLECLPPEPSPDDPESVKI 364
++ AE + Q+E+E + + + + D +++I
Sbjct: 979 KRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRI 1016
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 53.9 bits (128), Expect = 3e-07
Identities = 27/74 (36%), Positives = 49/74 (66%), Gaps = 3/74 (4%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRR 336
R E+EER + ++ RQ+++E LR++Q+ R++ E RE+ ++EEE ++L +ERR
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEE---KRLEQERRE 564
Query: 337 QNLQEEKERKLECL 350
Q L+ E+E + + L
Sbjct: 565 QRLKREQEERRDQL 578
Score = 53.5 bits (127), Expect = 4e-07
Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 3/105 (2%)
Query: 276 ERLEREER-NQTQVLRQQQDEAYLASLRADQE--KERKKREERERKRRKEEEVQQQKLAE 332
++L RE++ + Q LR++Q LR +Q+ +E++ R E++ +R +EEE +QK +
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 333 ERRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERR 377
ERR Q L+ E+E + + L E + E + +L D ERR
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR 485
Score = 52.0 bits (123), Expect = 1e-06
Identities = 25/72 (34%), Positives = 46/72 (63%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRR 336
R ++EER + Q R+QQ+E LR +QE+ R+++ RE++ + E+ +++ EERR
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374
Query: 337 QNLQEEKERKLE 348
Q L+ E++ + E
Sbjct: 375 QQLRREQQLRRE 386
Score = 51.2 bits (121), Expect = 2e-06
Identities = 29/79 (36%), Positives = 51/79 (64%), Gaps = 6/79 (7%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKK---REERERKRRKEEEVQQQKLAE 332
ER E++E + Q LR++Q+E LR +QE+ER++ R E+E +RR+++ ++Q+L
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Query: 333 E---RRRQNLQEEKERKLE 348
E RR Q L+ E++ + E
Sbjct: 386 EQQLRREQQLRREQQLRRE 404
Score = 51.2 bits (121), Expect = 2e-06
Identities = 29/73 (39%), Positives = 46/73 (63%), Gaps = 4/73 (5%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQ--QQKLAEE 333
E L+REER + + RQ+Q+ Y + QE+E+ REERE++RR+E E Q + K ++
Sbjct: 911 EELQREEREKRR--RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Query: 334 RRRQNLQEEKERK 346
+ Q L EE E++
Sbjct: 969 KEEQLLGEEPEKR 981
Score = 50.4 bits (119), Expect = 3e-06
Identities = 28/75 (37%), Positives = 51/75 (68%), Gaps = 3/75 (4%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEK--ERKKREERERKRRKEEEVQQQKLAEE 333
ERL++ R++ Q+ R++Q+E L+ ++EK E+++RE+R ++ ++E Q K EE
Sbjct: 526 ERLQQRLRSEQQL-RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584
Query: 334 RRRQNLQEEKERKLE 348
RR+Q L+ E+E +LE
Sbjct: 585 RRQQRLKREQEERLE 599
Score = 49.7 bits (117), Expect = 5e-06
Identities = 37/127 (29%), Positives = 70/127 (55%), Gaps = 12/127 (9%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQK---LAEE 333
R ERE++ + + QQ++E L +E+E+++R+E ER+ RK++E+QQ++ L EE
Sbjct: 983 RQEREKKYREEEELQQEEEQLLR-----EEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 334 RRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFS 393
R ++ LQE + + E E ++ + + + +ER++ + L + L
Sbjct: 1038 REKRRLQERERQYRE--EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL-- 1093
Query: 394 LKESPEK 400
L+E PEK
Sbjct: 1094 LREEPEK 1100
Score = 48.9 bits (115), Expect = 9e-06
Identities = 32/77 (41%), Positives = 47/77 (61%), Gaps = 12/77 (15%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKER----KKREERER-KRRKEEEVQQQKLA 331
+LE EER + Q R+QQ LR +QE+ R K++EE ER ++R E Q ++
Sbjct: 490 KLEEEERREQQERREQQ-------LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 332 EERRRQNLQEEKERKLE 348
EERR Q L+ E+E++LE
Sbjct: 543 EERREQLLKREEEKRLE 559
Score = 48.5 bits (114), Expect = 1e-05
Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 14/85 (16%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKK-----REERER-----KRRKEEEV 325
ERLE+EER + ++ R++ +E L +E+E ++ RE++ER KR +EEE
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Query: 326 QQQKLA----EERRRQNLQEEKERK 346
+Q+L EERR Q L EE++ +
Sbjct: 668 LEQRLKREHEEERREQELAEEEQEQ 692
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/128 (28%), Positives = 63/128 (49%), Gaps = 13/128 (10%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRR 336
RL+ ER + QQ+E L +E+E ++R+E ER+ RKEEE+QQ++ R
Sbjct: 1042 RLQERERQYREEEELQQEEEQLLG----EERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 337 QNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSR----VERRFHFSQSLTVIHDFLF 392
+ +ER+ +C E + E + + + R +ER++ + + + L
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQ---LLREEREKRRRQELERQYREEEEVQQEEEQL- 1153
Query: 393 SLKESPEK 400
L+E PEK
Sbjct: 1154 -LREEPEK 1160
Score = 47.8 bits (112), Expect = 2e-05
Identities = 43/153 (28%), Positives = 77/153 (50%), Gaps = 19/153 (12%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEK---ERKKREERER---KRRKEEEVQQQK 329
+RL+RE+ + L ++++E L+ +QE+ +R KREE ER + R+E+ +++++
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
Query: 330 LAEERRRQNL--QEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHFSQSLTVI 387
EERR+Q L +E++ER+ + L E + +K R E Q L
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK---------REEEEERLEQRLKRE 675
Query: 388 HDFLFSLKESPEKFQIEANFPRRVLPCIPSEEW 420
H+ +E E+ Q +A R+ IP +W
Sbjct: 676 HEEERREQELAEEEQEQAR--ERIKSRIPKWQW 706
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/108 (27%), Positives = 58/108 (53%), Gaps = 7/108 (6%)
Query: 241 RRMTVVGRLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLAS 300
+R TV+ + E +Q ++ Q + Q +LER+E + + +QQ +
Sbjct: 248 KRETVLRKEEEKLQEEEPQRQRELQEEEEQL----RKLERQELRRERQEEEQQQQRLRRE 303
Query: 301 LRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
+ +++E ++RE++E +R ++E +QQ EERR Q L+ E+E + E
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQ---EERREQQLRREQEERRE 348
Score = 47.4 bits (111), Expect = 3e-05
Identities = 22/68 (32%), Positives = 42/68 (61%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
+ EE+ Q ++ R+QQ R +Q++ER++++ER ++ + E Q ++ EERR Q
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350
Query: 339 LQEEKERK 346
L+ E+E +
Sbjct: 351 LRREQEEE 358
Score = 47.4 bits (111), Expect = 3e-05
Identities = 26/75 (34%), Positives = 51/75 (68%), Gaps = 5/75 (6%)
Query: 276 ERLEREE---RNQTQVLRQQQDEAYLASLRADQEKERKKRE-ERERKRRKEEEVQQQKLA 331
+RL RE+ R Q + R+QQ+E R +Q++ER++++ RE++ R+E+++++++
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQ-E 356
Query: 332 EERRRQNLQEEKERK 346
EERR Q L+ E+E +
Sbjct: 357 EERREQQLRREQEEE 371
Score = 47.4 bits (111), Expect = 3e-05
Identities = 29/79 (36%), Positives = 53/79 (67%), Gaps = 6/79 (7%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERK-RRKEEEVQQQKL--- 330
+ER E+E R Q Q+ R Q++E L+ ++E+ R+++E RE++ RR++EE ++Q+L
Sbjct: 464 TERHEQERRKQ-QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ 522
Query: 331 -AEERRRQNLQEEKERKLE 348
EER +Q L+ E++ + E
Sbjct: 523 EEEERLQQRLRSEQQLRRE 541
Score = 47.4 bits (111), Expect = 3e-05
Identities = 25/76 (32%), Positives = 47/76 (61%), Gaps = 3/76 (3%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKL---AE 332
++L RE+ + + L ++++E L R +Q +R++ E R++ ++EEE +QQ+L E
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 333 ERRRQNLQEEKERKLE 348
ER Q L+ E+ +LE
Sbjct: 596 ERLEQRLKREEVERLE 611
Score = 47.0 bits (110), Expect = 3e-05
Identities = 30/77 (38%), Positives = 46/77 (59%), Gaps = 13/77 (16%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQ--------EKERKKREERERKRRKEEEVQQ 327
E+L REER + + RQ+++ Y + Q E E+++R+ERE+K R+EEE+QQ
Sbjct: 941 EQLLREEREKRR--RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
Query: 328 ---QKLAEERRRQNLQE 341
Q L EER ++ QE
Sbjct: 999 EEEQLLREEREKRRRQE 1015
Score = 45.8 bits (107), Expect = 8e-05
Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 6/83 (7%)
Query: 270 QTYLVSERLEREERNQTQVLR------QQQDEAYLASLRADQEKERKKREERERKRRKEE 323
Q + E E+E R + VLR Q+++ L+ ++E+ RK + R+ R+EE
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 324 EVQQQKLAEERRRQNLQEEKERK 346
E QQQ+L E++ + QEE+ R+
Sbjct: 294 EQQQQRLRREQQLRRKQEEERRE 316
Score = 45.8 bits (107), Expect = 8e-05
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 12/82 (14%)
Query: 267 DANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREER---ERKRRKEE 323
+ Q L SE E+EER Q Q+ R+QQ+ R +Q +R++ EER KR EE
Sbjct: 628 ERRQQLLKSE--EQEERRQQQLRREQQE-------RREQRLKREEEEERLEQRLKREHEE 678
Query: 324 EVQQQKLAEERRRQNLQEEKER 345
E ++Q+LAEE + Q + K R
Sbjct: 679 ERREQELAEEEQEQARERIKSR 700
Score = 45.4 bits (106), Expect = 1e-04
Identities = 36/136 (26%), Positives = 66/136 (48%), Gaps = 9/136 (6%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
E+ ER RQQ+++ +L ++EKE+++R+ RER++ + ++++L R Q
Sbjct: 792 EQRERQLRAEERQQREQRFLPE---EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848
Query: 339 LQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFS----L 394
LQEE++ E S + K ++L + + RR H + + + L L
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERK--RRRHTLYAKPALQEQLRKEQQLL 906
Query: 395 KESPEKFQIEANFPRR 410
+E E+ Q E RR
Sbjct: 907 QEEEEELQREEREKRR 922
Score = 45.1 bits (105), Expect = 1e-04
Identities = 39/130 (30%), Positives = 68/130 (52%), Gaps = 14/130 (10%)
Query: 279 EREERNQTQVLRQQQDEAYLAS-----LRADQEKERKKREERERKRRKEEEVQQQKLAEE 333
ERE R + ++ RQ + E L LR + EK R++ ERER+ R+EEE+QQ++ E+
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ--ERERQCREEEELQQEE--EQ 1122
Query: 334 RRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSR---VERRFHFSQSLTVIHDF 390
R+ ++ + ++LE E E +++ + P R +ER++ + L +
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Query: 391 LFSLKESPEK 400
L L+E EK
Sbjct: 1183 L--LREEQEK 1190
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/71 (36%), Positives = 45/71 (63%), Gaps = 7/71 (9%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRAD--QEKERKKREERERKRRKEEEVQQQKLAEER 334
R E E+R + ++ RQ ++E L +E++ K+R+ERER+ R+EEE+Q+QK
Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK----- 1209
Query: 335 RRQNLQEEKER 345
R+Q ++E +R
Sbjct: 1210 RKQRYRDEDQR 1220
Score = 44.7 bits (104), Expect = 2e-04
Identities = 29/98 (29%), Positives = 59/98 (60%), Gaps = 14/98 (14%)
Query: 271 TYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQK- 329
T L+ + R + Q+L+++++E +E+E+++R+E+ER+ R+EE++QQ++
Sbjct: 888 TLYAKPALQEQLRKEQQLLQEEEEELQR------EEREKRRRQEQERQYREEEQLQQEEE 941
Query: 330 --LAEER--RRQNLQE---EKERKLECLPPEPSPDDPE 360
L EER RR+ +E K++KL+ + ++PE
Sbjct: 942 QLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE 979
Score = 44.7 bits (104), Expect = 2e-04
Identities = 26/78 (33%), Positives = 48/78 (61%), Gaps = 6/78 (7%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRAD---QEKERKKREERERKRRKEEEVQQ---QKL 330
R ERE+R + ++ RQ ++E + +E E+++R+E ER+ R+EEE+QQ Q L
Sbjct: 1125 REEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184
Query: 331 AEERRRQNLQEEKERKLE 348
EE+ ++ + E++ + E
Sbjct: 1185 REEQEKRRQERERQYREE 1202
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/75 (42%), Positives = 46/75 (61%), Gaps = 16/75 (21%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLA---------SLRADQE----KERKKREERERKRRKE 322
E+L+ EE Q Q LRQ++D Y A S R +QE +E+K+R+ERERK R E
Sbjct: 1826 EQLQLEE--QEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR-E 1882
Query: 323 EEVQQQKLAEERRRQ 337
E +++Q+ E+R RQ
Sbjct: 1883 EHIRRQQKEEQRHRQ 1897
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 6/83 (7%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERER--KRRKEEEVQQQKLAEE 333
+RLE+E R Q Q++ L ++ ++R KRE+ ER +R K EEV++ + EE
Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLE-QEE 614
Query: 334 RRRQNL---QEEKERKLECLPPE 353
RR Q L + E+ER+ + L E
Sbjct: 615 RREQRLKREEPEEERRQQLLKSE 637
Score = 43.5 bits (101), Expect = 4e-04
Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 5/78 (6%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREE-----RERKRRKEEEVQQQKL 330
+RL R+ER + + +QQ + Q+++RK REE R+ + RK E +QQ
Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR 1440
Query: 331 AEERRRQNLQEEKERKLE 348
+ER R+ L+EE++ + E
Sbjct: 1441 RQERERKFLEEEQQLRQE 1458
Score = 42.7 bits (99), Expect = 7e-04
Identities = 34/116 (29%), Positives = 61/116 (52%), Gaps = 15/116 (12%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREER--------ERKRRKEEEVQQ 327
+RL+RE+ + L+++++ R Q+ +R + EER E +RR+++E ++
Sbjct: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504
Query: 328 QKL---AEERRRQNL--QEEKERKLECLPPEPS--PDDPESVKIIFKLPNDSRVER 376
Q+L EERR Q L QEE+ER + L E + E + + K + R+E+
Sbjct: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Score = 42.7 bits (99), Expect = 7e-04
Identities = 28/72 (38%), Positives = 49/72 (68%), Gaps = 8/72 (11%)
Query: 276 ERLEREERNQTQVL-RQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
E+LEREE+ + + R+ Q+E L LR ++E E+++R+E +RK R+EE++ Q++ +
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQL--LREERE-EKRRRQETDRKFREEEQLLQEREEQPL 1353
Query: 335 RRQNLQEEKERK 346
RRQ E++RK
Sbjct: 1354 RRQ----ERDRK 1361
Score = 42.7 bits (99), Expect = 7e-04
Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 4/70 (5%)
Query: 281 EERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEE----VQQQKLAEERRR 336
+ER + + RQ++D + QE+ RK EE +R RR+E E ++Q+L + R
Sbjct: 1346 QEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQERE 1405
Query: 337 QNLQEEKERK 346
Q L+++++RK
Sbjct: 1406 QQLRQDRDRK 1415
Score = 42.7 bits (99), Expect = 7e-04
Identities = 26/69 (37%), Positives = 45/69 (65%), Gaps = 8/69 (11%)
Query: 281 EERNQTQVLRQQQDEAYL---ASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQ 337
+ER + Q+ RQ++D +L LR QE+E++ R +R+RK R+EE++ Q+ ++ RRQ
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRR-QEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ 1687
Query: 338 NLQEEKERK 346
E++RK
Sbjct: 1688 ----ERDRK 1692
Score = 42.7 bits (99), Expect = 7e-04
Identities = 26/70 (37%), Positives = 45/70 (64%), Gaps = 8/70 (11%)
Query: 280 REERNQTQVLRQQQDEAYLAS--LRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQ 337
R+E Q Q+ RQ++ L LR ++E+++ +R+ER+RK R+EE+++Q ER Q
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ-----EREEQ 1786
Query: 338 NLQ-EEKERK 346
L+ +E +RK
Sbjct: 1787 QLRSQESDRK 1796
Score = 42.7 bits (99), Expect = 7e-04
Identities = 24/83 (28%), Positives = 50/83 (60%), Gaps = 7/83 (8%)
Query: 273 LVSERLEREERNQTQVLRQQQDEAYL--ASLRADQEKERKKREERERKRRKEEEVQQQKL 330
++ E R ER + Q+ RQ++D + LR ++E+++ + +E +RK R+EE+++Q++
Sbjct: 1749 ILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
Query: 331 AEERRRQNLQ-----EEKERKLE 348
++ R Q EE++ +LE
Sbjct: 1809 EQQLRPQQRDGKYRWEEEQLQLE 1831
Score = 42.4 bits (98), Expect = 9e-04
Identities = 31/74 (41%), Positives = 45/74 (60%), Gaps = 13/74 (17%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRR 336
R REE+ Q + R++QD + QE+E K+ +RE RKEEE Q++ E +R+
Sbjct: 220 RKGREEKQQQR--RERQDRVF-------QEEEEKEWRKRETVLRKEEEKLQEE--EPQRQ 268
Query: 337 QNLQEEKE--RKLE 348
+ LQEE+E RKLE
Sbjct: 269 RELQEEEEQLRKLE 282
Score = 42.4 bits (98), Expect = 9e-04
Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 11/78 (14%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQ------KL 330
R ERE + + + QQ++E L R ++EK R R+E ER+ R+EEEVQQ+ +
Sbjct: 1103 RQERERQCREEEELQQEEEQLL---REEREKRR--RQELERQYREEEEVQQEEEQLLREE 1157
Query: 331 AEERRRQNLQEEKERKLE 348
E+RRRQ L+ + + E
Sbjct: 1158 PEKRRRQELERQYREEEE 1175
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/75 (32%), Positives = 46/75 (61%), Gaps = 17/75 (22%)
Query: 281 EERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEE-----------EVQQQK 329
+ER + Q+ RQ++D +L +E+++ +R+ER+RK R++E E +QQ
Sbjct: 1471 QEREEQQLHRQERDRKFL------EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Query: 330 LAEERRRQNLQEEKE 344
++R+R+ LQEE++
Sbjct: 1525 HRQQRQRKFLQEEQQ 1539
Score = 41.6 bits (96), Expect = 0.001
Identities = 26/85 (30%), Positives = 48/85 (56%), Gaps = 16/85 (18%)
Query: 276 ERLEREERNQTQVLRQQQDEAYL--ASLRADQEKERKKREERERKRRKEEE--------- 324
++L R+ER Q + RQ +D + LR ++E+++ R+ER+RK R EE+
Sbjct: 1538 QQLRRQERGQQR--RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595
Query: 325 ---VQQQKLAEERRRQNLQEEKERK 346
+Q+L + +Q L++E++RK
Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQERDRK 1620
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/86 (31%), Positives = 49/86 (56%), Gaps = 10/86 (11%)
Query: 265 IMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEE 324
+ + + L + +R+ R + Q LR+Q+ E QE+++ +R+E ERK R+EE+
Sbjct: 1676 LQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL-----QEEQQLRRQELERKFREEEQ 1730
Query: 325 VQQQKLAEERRRQ-----NLQEEKER 345
++Q+ E+ RRQ L+EE+ R
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLR 1756
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/80 (33%), Positives = 49/80 (61%), Gaps = 18/80 (22%)
Query: 276 ERLEREERN------QTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEV---- 325
++L R+ER+ + QV RQ+++ +L E+E++ R+ER RK R+EE++
Sbjct: 1421 QQLSRQERDRKFREEEQQVRRQERERKFL-------EEEQQLRQERHRKFREEEQLLQER 1473
Query: 326 -QQQKLAEERRRQNLQEEKE 344
+QQ +ER R+ L+EE++
Sbjct: 1474 EEQQLHRQERDRKFLEEEQQ 1493
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/89 (34%), Positives = 52/89 (58%), Gaps = 12/89 (13%)
Query: 267 DANQTYLVSERLEREERNQTQVLRQQQDEAYLASLR--ADQEKERKKREERERKRRKEEE 324
D ++ + E+L R+ER + Q+ RQ++D + + QE+ERK E+ ++ RR+E
Sbjct: 1552 DRDRKFREEEQL-RQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE-- 1608
Query: 325 VQQQKLAEERRR------QNLQEEKERKL 347
QQ+L +ER R Q LQE +E++L
Sbjct: 1609 -GQQQLRQERDRKFREDEQLLQEREEQQL 1636
Score = 40.8 bits (94), Expect = 0.003
Identities = 25/85 (29%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
+R EE Q + ++Q+ E LA EK+ ++ E+R+R+RR EE +Q++ +ER
Sbjct: 126 DRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQ-ERLEQRDRQRRDEELWRQRQEWQERE 184
Query: 336 RQNLQEEKERKLECLPPEPSPDDPE 360
+ +EE+ + + E PD+ +
Sbjct: 185 ERRAEEEQLQSCKGHETEEFPDEEQ 209
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/111 (25%), Positives = 58/111 (52%), Gaps = 9/111 (8%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQ--KLAEE 333
E+ +ER + ++ R+Q++ + E+ ++R +++ KR +EEE +++ KL EE
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494
Query: 334 RRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHFSQSL 384
RR E++ER+ + L E + +K + + R+++R Q L
Sbjct: 495 ERR----EQQERREQQLRREQEERREQRLK---RQEEEERLQQRLRSEQQL 538
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/82 (29%), Positives = 49/82 (59%), Gaps = 3/82 (3%)
Query: 267 DANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQ--EKERKKREERERKRRKEEE 324
++++ + E+L R+ER + Q+ QQ+D Y Q E+E++ R+ER+R+ R EE+
Sbjct: 1792 ESDRKFREEEQL-RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQ 1850
Query: 325 VQQQKLAEERRRQNLQEEKERK 346
Q+ + ++ QEE++++
Sbjct: 1851 FATQEKSRREEQELWQEEEQKR 1872
Score = 40.4 bits (93), Expect = 0.003
Identities = 18/42 (42%), Positives = 32/42 (76%), Gaps = 2/42 (4%)
Query: 305 QEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERK 346
QE +R+++E+ E++RR+E E+Q Q+ EER + QEE++R+
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQE--EERAHRQQQEEEQRR 765
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/84 (35%), Positives = 49/84 (58%), Gaps = 14/84 (16%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLR--ADQEKERKKREERERKRRKEEE----VQQQK 329
++L +ER Q LRQ +D + + + QE++RK REE ++ RR+E E ++Q+
Sbjct: 1397 QQLRCQEREQQ--LRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
Query: 330 LAEERRR------QNLQEEKERKL 347
L +ER R Q LQE +E++L
Sbjct: 1455 LRQERHRKFREEEQLLQEREEQQL 1478
Score = 39.7 bits (91), Expect = 0.006
Identities = 25/87 (28%), Positives = 50/87 (57%), Gaps = 20/87 (22%)
Query: 276 ERLEREERN----QTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEV------ 325
++L R+ER+ + + LRQ+++E L S QE +RK REE + ++ +EE+
Sbjct: 1762 QQLRRQERDRKFREEEQLRQEREEQQLRS----QESDRKFREEEQLRQEREEQQLRPQQR 1817
Query: 326 ------QQQKLAEERRRQNLQEEKERK 346
++++L E + Q L++E++R+
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQ 1844
Score = 39.3 bits (90), Expect = 0.007
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 4/86 (4%)
Query: 267 DANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERK--KREERERKRRKEEE 324
D ++ L R E ++R RQ ++E + QE+ER+ + EE+ K+ + E+
Sbjct: 104 DGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQ 163
Query: 325 VQQQKLAEE--RRRQNLQEEKERKLE 348
+Q+ EE R+RQ QE +ER+ E
Sbjct: 164 RDRQRRDEELWRQRQEWQEREERRAE 189
Score = 39.3 bits (90), Expect = 0.007
Identities = 28/76 (36%), Positives = 47/76 (61%), Gaps = 7/76 (9%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERK--KREERERKRRKEE---EVQQQKL 330
++L REER + + RQ+ D + + QE+E + +R+ER+RK R+EE + Q +K
Sbjct: 1318 KQLLREEREEKR-RRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKF 1376
Query: 331 AEERRRQNLQEEKERK 346
EE +R ++E+ERK
Sbjct: 1377 LEEEQRLR-RQERERK 1391
Score = 38.9 bits (89), Expect = 0.010
Identities = 24/82 (29%), Positives = 48/82 (58%), Gaps = 8/82 (9%)
Query: 276 ERLEREERN----QTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLA 331
E+L R+ER + + LR +++E L QE++RK REE + ++ +EE+ + + +
Sbjct: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRR----QERDRKFREEEQLRQEREEQQLRSQES 1793
Query: 332 EERRRQNLQEEKERKLECLPPE 353
+ + R+ Q +ER+ + L P+
Sbjct: 1794 DRKFREEEQLRQEREEQQLRPQ 1815
Score = 38.5 bits (88), Expect = 0.012
Identities = 24/82 (29%), Positives = 49/82 (59%), Gaps = 10/82 (12%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRA--DQEKERKKREERERKRRKEEEVQQQKLAE 332
+E+ + E +Q + + QQD +L + D+E+ER++ ++R+R +EE++++++ E
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
Query: 333 ERRR--------QNLQEEKERK 346
+RR Q L+EE+E K
Sbjct: 1307 AKRRDRKSQEEKQLLREEREEK 1328
Score = 38.5 bits (88), Expect = 0.012
Identities = 22/81 (27%), Positives = 45/81 (55%), Gaps = 10/81 (12%)
Query: 276 ERLEREERN------QTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEE----V 325
++L R+ER+ + Q+ RQ++D + QE ERK EE ++ R++ +
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ 1535
Query: 326 QQQKLAEERRRQNLQEEKERK 346
++Q+L + R Q +++++RK
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRK 1556
Score = 38.5 bits (88), Expect = 0.012
Identities = 22/73 (30%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
++L R++R + + +QQ + Q+++RK REE + ++ +EE QQ E R
Sbjct: 1522 QQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE--QQLSRQERDR 1579
Query: 336 RQNLQEEKERKLE 348
+ L+E+K R+ E
Sbjct: 1580 KFRLEEQKVRRQE 1592
Score = 38.5 bits (88), Expect = 0.012
Identities = 25/82 (30%), Positives = 50/82 (60%), Gaps = 13/82 (15%)
Query: 276 ERLEREERN------QTQVLRQQQDEAYLASLRA--DQEKERKKREERERKRRKEEEV-- 325
++L R+ER+ + +V RQ+Q+ ++ + QE +++ R+ER+RK R++E++
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 326 ---QQQKLAEERRRQNLQEEKE 344
+QQ +ER R+ L+EE +
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQ 1651
Score = 38.5 bits (88), Expect = 0.012
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 7/70 (10%)
Query: 277 RLEREERNQTQVLRQQQDEAYLAS--LRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
+L R+ER Q LR +D + L + E+++ +R+ER+RK R EEE QQ +ER
Sbjct: 1651 QLRRQEREQQ--LRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR-EEE--QQLRRQER 1705
Query: 335 RRQNLQEEKE 344
R+ LQEE++
Sbjct: 1706 ERKFLQEEQQ 1715
Score = 38.5 bits (88), Expect = 0.012
Identities = 26/79 (32%), Positives = 47/79 (59%), Gaps = 12/79 (15%)
Query: 276 ERLEREERN-----QTQVLRQQQDEAYLAS---LRADQEKERKKREERERKRRKEEEVQQ 327
++L R+ER + Q LR+Q+ E LR + E+E+ +R+ER RK +EE+++
Sbjct: 1698 QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP 1757
Query: 328 QKLAEERRRQNLQEEKERK 346
++ ++ RRQ E++RK
Sbjct: 1758 EREEQQLRRQ----ERDRK 1772
Score = 38.1 bits (87), Expect = 0.016
Identities = 22/80 (27%), Positives = 44/80 (55%), Gaps = 3/80 (3%)
Query: 267 DANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQ 326
+ + ++ E+ R + Q Q LRQ++D + + QE+E ++ +ER R+ EE
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQ-LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEE-- 1648
Query: 327 QQKLAEERRRQNLQEEKERK 346
+ +L + R Q L+ +++RK
Sbjct: 1649 EPQLRRQEREQQLRHDRDRK 1668
Score = 37.7 bits (86), Expect = 0.021
Identities = 23/87 (26%), Positives = 48/87 (55%), Gaps = 13/87 (14%)
Query: 272 YLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLA 331
+L+ E+ ER+ + + R QQ + + + +E+K+ + R+RK ++E+++ +++
Sbjct: 1269 HLLGEQQERDREQERR--RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREERE 1326
Query: 332 EERRRQN-----------LQEEKERKL 347
E+RRRQ LQE +E+ L
Sbjct: 1327 EKRRRQETDRKFREEEQLLQEREEQPL 1353
Score = 37.7 bits (86), Expect = 0.021
Identities = 26/88 (29%), Positives = 51/88 (57%), Gaps = 13/88 (14%)
Query: 267 DANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEE--- 323
D ++ + E+L +E Q Q+ RQ++D + +E+++ +R+ERERK +EE
Sbjct: 1664 DRDRKFREEEQLLQEGEEQ-QLRRQERDRKFR------EEEQQLRRQERERKFLQEEQQL 1716
Query: 324 ---EVQQQKLAEERRRQNLQEEKERKLE 348
E++++ EE+ RQ ++E+ R+ E
Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQE 1744
Score = 37.4 bits (85), Expect = 0.028
Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 16/82 (19%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKK---------REERERKRRKEEEVQQQK 329
+ EER Q ++Q + +A+++ ER + RE+RER+ R EE Q+++
Sbjct: 749 QEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQ 808
Query: 330 L-------AEERRRQNLQEEKE 344
E+RRRQ + EKE
Sbjct: 809 RFLPEEEEKEQRRRQRREREKE 830
Score = 37.0 bits (84), Expect = 0.036
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 18/84 (21%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREER----------ERKRRKEEEV 325
E+L+R ER Q L++++D L+ DQE+ R + + R ERKRR+
Sbjct: 838 EQLQRRER--AQQLQEEED-----GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLY 890
Query: 326 QQQKLAEE-RRRQNLQEEKERKLE 348
+ L E+ R+ Q L +E+E +L+
Sbjct: 891 AKPALQEQLRKEQQLLQEEEEELQ 914
Score = 36.6 bits (83), Expect = 0.047
Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
E E EE+++ Q +Q+D R D+E R+++E +ER+ R+ EE Q Q
Sbjct: 147 ELAEGEEQSEKQERLEQRDRQ-----RRDEELWRQRQEWQEREERRAEEEQLQSCKGHET 201
Query: 336 RQNLQEEKERKLECL 350
+ EE+ R+ E L
Sbjct: 202 EEFPDEEQLRRRELL 216
Score = 36.6 bits (83), Expect = 0.047
Identities = 18/73 (24%), Positives = 44/73 (60%), Gaps = 2/73 (2%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRR--KEEEVQQQKLAEE 333
E+ ++ Q +V ++++++ + +++E K +EE +++R +EEE Q +KL +
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Query: 334 RRRQNLQEEKERK 346
R+ QEE++++
Sbjct: 285 ELRRERQEEEQQQ 297
Score = 36.6 bits (83), Expect = 0.047
Identities = 23/96 (23%), Positives = 51/96 (53%), Gaps = 17/96 (17%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKE------------EE 324
R E ++ + + L +++++ R ++EKE + EE E+ +R+E +E
Sbjct: 799 RAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQE 858
Query: 325 VQQQKLAEERRRQ-----NLQEEKERKLECLPPEPS 355
Q+++ ++E+RR L+EE++R+ L +P+
Sbjct: 859 DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA 894
Score = 35.4 bits (80), Expect = 0.11
Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 277 RLEREER--NQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
R ERE + + Q LRQ++ + + QE+E ++ +ER R+ EE QQ + E
Sbjct: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
Query: 335 RRQNLQE----EKERK 346
R+ QE E ERK
Sbjct: 1501 RKFREQELRSQEPERK 1516
Score = 35.0 bits (79), Expect = 0.14
Identities = 30/77 (38%), Positives = 48/77 (62%), Gaps = 10/77 (12%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER--RR 336
+R+ R + Q+L++ +++ LR QE++RK REE ++ RR+E E ++ L EE+ RR
Sbjct: 1666 DRKFREEEQLLQEGEEQ----QLRR-QERDRKFREEEQQLRRQERE--RKFLQEEQQLRR 1718
Query: 337 QNLQEEKERKLECLPPE 353
Q L E K R+ E L E
Sbjct: 1719 QEL-ERKFREEEQLRQE 1734
Score = 34.7 bits (78), Expect = 0.18
Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 3/71 (4%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQ---QKLAEERR 335
ER+ R T + E + QE+E + + E KRR++E+ +Q ++ ++
Sbjct: 881 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
Query: 336 RQNLQEEKERK 346
Q L+EE+E++
Sbjct: 941 EQLLREEREKR 951
Score = 34.7 bits (78), Expect = 0.18
Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 15/77 (19%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLAS---LRADQEKERKKREERERKR------RKEEEVQ 326
+ LER+ R + +V QQ++E L R QE ER+ REE E ++ R+E+E +
Sbjct: 1134 QELERQYREEEEV--QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191
Query: 327 QQKLAEERRRQNLQEEK 343
+Q ER RQ +EE+
Sbjct: 1192 RQ----ERERQYREEEE 1204
Score = 34.7 bits (78), Expect = 0.18
Identities = 32/106 (30%), Positives = 54/106 (50%), Gaps = 24/106 (22%)
Query: 264 FIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERK------------- 310
F+ + Q L + LER+ R + Q LRQ+ ++ L QE+ RK
Sbjct: 1709 FLQEEQQ--LRRQELERKFREEEQ-LRQETEQEQLRR----QERYRKILEEEQLRPEREE 1761
Query: 311 ---KREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPE 353
+R+ER+RK R+EE+++Q++ E++ R + K R+ E L E
Sbjct: 1762 QQLRRQERDRKFREEEQLRQER-EEQQLRSQESDRKFREEEQLRQE 1806
Score = 34.3 bits (77), Expect = 0.23
Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 9/92 (9%)
Query: 261 QLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRR 320
QL DA Q+ + S R + + Q RQ+Q+E R +E E + +EE R+
Sbjct: 707 QLESEADARQSKVYS----RPRKQEGQRRRQEQEEK-----RRRRESELQWQEEERAHRQ 757
Query: 321 KEEEVQQQKLAEERRRQNLQEEKERKLECLPP 352
++EE Q++ + + + E ++L PP
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERGRQRLSARPP 789
Score = 33.9 bits (76), Expect = 0.31
Identities = 22/80 (27%), Positives = 47/80 (58%), Gaps = 10/80 (12%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRK---------EEEVQ 326
E+ E++ER + Q RQ++DE + QE+E ++ EE + + K EE+++
Sbjct: 153 EQSEKQERLE-QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211
Query: 327 QQKLAEERRRQNLQEEKERK 346
+++L E RR+ +++++R+
Sbjct: 212 RRELLELRRKGREEKQQQRR 231
Score = 33.1 bits (74), Expect = 0.52
Identities = 35/133 (26%), Positives = 63/133 (47%), Gaps = 11/133 (8%)
Query: 279 EREERN----QTQVLRQQQDEAYL--ASLRADQ--EKERKKREER--ERKRRKEEEVQQQ 328
EREER Q Q + + E + LR + E RK REE+ +R+ R++ Q++
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE 241
Query: 329 KLAEERRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLP-NDSRVERRFHFSQSLTVI 387
+ E R+R+ + ++E KL+ P+ + E + + KL + R ER+ Q +
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301
Query: 388 HDFLFSLKESPEK 400
+ K+ E+
Sbjct: 302 REQQLRRKQEEER 314
Score = 32.7 bits (73), Expect = 0.68
Identities = 20/84 (23%), Positives = 46/84 (54%), Gaps = 10/84 (11%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKK------REERERKRRKEEEVQQQK 329
E+ E+ R ++++ Q+++ A+ R QE+E+++ + E + +R ++ +
Sbjct: 734 EQEEKRRRRESELQWQEEERAH----RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPP 789
Query: 330 LAEERRRQNLQEEKERKLECLPPE 353
L E+R RQ EE++++ + PE
Sbjct: 790 LREQRERQLRAEERQQREQRFLPE 813
Score = 31.6 bits (70), Expect = 1.5
Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 13/86 (15%)
Query: 274 VSERLERE---ERNQTQVLRQQQDEA----------YLASLRADQEKERKKREERERKRR 320
+ +RL+RE ER + ++ ++Q++A + L ++ + + K R RK+
Sbjct: 668 LEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE 727
Query: 321 KEEEVQQQKLAEERRRQNLQEEKERK 346
+ Q+Q+ RR LQ ++E +
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEER 753
Score = 29.6 bits (65), Expect = 5.8
Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 16/87 (18%)
Query: 276 ERLEREERNQT--QVLRQQQDEAYLASLRADQEK-------ERKKREERERKRRKEEEVQ 326
ERLE+ +R + ++ RQ+Q+ RA++E+ E ++ + E+ RR+E
Sbjct: 159 ERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLEL 218
Query: 327 QQKLAEERRRQN-------LQEEKERK 346
++K EE+++Q QEE+E++
Sbjct: 219 RRKGREEKQQQRRERQDRVFQEEEEKE 245
Score = 29.3 bits (64), Expect = 7.5
Identities = 21/89 (23%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 268 ANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQ 327
A + + E+ REE+ Q Q++ + LR + + ++K E+R R +V +
Sbjct: 1847 AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHR------QVGE 1900
Query: 328 QKLAEERRRQNLQEEKERKLECLPPEPSP 356
K E + L E + +P SP
Sbjct: 1901 IKSQEGKGHGRLLEPGTHQFASVPVRSSP 1929
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 52.8 bits (125), Expect = 6e-07
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Query: 196 PEVISLINTRMLFWACSTNKPEGYRVSQALRENTYPFLAMIMLKDRRMTVVGRLEGLIQP 255
PE S+++ L ST+ PEG +T PF L RR+T + ++
Sbjct: 276 PEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPL--RRIT-----KKFVKG 328
Query: 256 DDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYL-ASLRADQEKERKKREE 314
N+L D Q L + R ER + + L+++ A A + ++EKE K++E
Sbjct: 329 STEKNKLRLQRD--QERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER 386
Query: 315 RERKRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
RE++ + E+E +++ +E RR+ QE E KLE
Sbjct: 387 REKREKDEKEKAEKQRLKEERRKERQEALEAKLE 420
Score = 31.6 bits (70), Expect = 1.5
Identities = 16/51 (31%), Positives = 29/51 (56%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQ 326
E+ + E++ + R+++ EA A L ++KE +KR E KR K E+ +
Sbjct: 394 EKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 51.6 bits (122), Expect = 1e-06
Identities = 32/91 (35%), Positives = 52/91 (57%), Gaps = 8/91 (8%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQ---EKERKKREERERKRRKEEEVQQQKLAEERR 335
ERE+ + RQQ+ E L + Q EKERK+ +E+E +R+KE+E + QK+ E+ +
Sbjct: 526 EREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEK 585
Query: 336 RQNLQEEKERKLECLPP-----EPSPDDPES 361
L++E+E+ E + P EP + ES
Sbjct: 586 ECELEKEREKLEEKIEPREPNLEPMVEKQES 616
Score = 47.8 bits (112), Expect = 2e-05
Identities = 19/75 (25%), Positives = 48/75 (64%)
Query: 274 VSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEE 333
+ ER +ER + + L ++Q++ D+E++++K +E E+++ K+ E+++++ E+
Sbjct: 504 IREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEK 563
Query: 334 RRRQNLQEEKERKLE 348
+ Q+EKE++L+
Sbjct: 564 EKELERQKEKEKELQ 578
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 9/91 (9%)
Query: 266 MDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKK------REERERKR 319
M+ + +E+L+R + + +L +Q + ++E+ER+K +ERE++R
Sbjct: 473 MEEQRKAACAEKLKRLDE-KLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKER 531
Query: 320 RKEEEVQQQKLAEERRRQNLQE--EKERKLE 348
K+ E QQ+K E + Q Q EKERK E
Sbjct: 532 EKDRERQQEKEKELEKEQEKQREMEKERKQE 562
Score = 40.4 bits (93), Expect = 0.003
Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 14/87 (16%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEK--------------ERKKREERERKRRK 321
ER + + + + +Q+ A L+ EK ER++ +ERER++
Sbjct: 460 ERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKEL 519
Query: 322 EEEVQQQKLAEERRRQNLQEEKERKLE 348
E+E +Q++ E + + Q+EKE++LE
Sbjct: 520 EKEQEQEREKEREKDRERQQEKEKELE 546
Score = 37.0 bits (84), Expect = 0.036
Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 7/72 (9%)
Query: 290 RQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKER---K 346
+Q DE + R Q+ E ER RKRR+EEE + EE+R+ E+ +R K
Sbjct: 436 QQVADEDEIWKQRRRQQSEISAAVERARKRREEEE----RRMEEQRKAACAEKLKRLDEK 491
Query: 347 LECLPPEPSPDD 358
L L +PSP++
Sbjct: 492 LGILEKQPSPEE 503
Score = 37.0 bits (84), Expect = 0.036
Identities = 26/114 (22%), Positives = 59/114 (51%), Gaps = 10/114 (8%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
+ LE+E+ Q ++ ++++ E ++E ER+K +E+E ++ KE Q+++ E+
Sbjct: 543 KELEKEQEKQREMEKERKQEK-------EKELERQKEKEKELQKMKE---QEKECELEKE 592
Query: 336 RQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHFSQSLTVIHD 389
R+ L+E+ E + L P + E+ + P +R + ++ V+H+
Sbjct: 593 REKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHE 646
Score = 32.3 bits (72), Expect = 0.89
Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Query: 309 RKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPESVK 363
R +EERE+++ KE E + +K+ E + ++ EK K + PP P P P ++
Sbjct: 1022 RDMKEEREQRKEKEGE-KAEKVTE---KVVVKPEKTEKKDLPPPPPPPQPPAPIQ 1072
Score = 29.3 bits (64), Expect = 7.5
Identities = 22/70 (31%), Positives = 39/70 (55%), Gaps = 11/70 (15%)
Query: 290 RQQQDEAYLASLRADQEKERKKRE-ERERK-------RRKEEE---VQQQKLAEERRRQN 338
R+QQ E A RA + +E ++R E +RK +R +E+ +++Q EE R +
Sbjct: 449 RRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERE 508
Query: 339 LQEEKERKLE 348
++E+ER+ E
Sbjct: 509 REKEREREKE 518
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 14/101 (13%)
Query: 273 LVSERLEREERNQTQVLRQQQDEAYLASLRADQ--------------EKERKKREERERK 318
L ERLERE Q Q+ R++Q+ L + ++ER++R+ERER
Sbjct: 176 LERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERL 235
Query: 319 RRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDP 359
R E E Q+++ E+ R+ L+ E+ER++ S + P
Sbjct: 236 ERLERERQERERQEQLEREQLEWERERRISSAAAPASVETP 276
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/79 (30%), Positives = 45/79 (56%)
Query: 270 QTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQK 329
Q L ERLERE + ++ R++ + L R +QE+ ++R+ERER+ R E + + ++
Sbjct: 153 QKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLER 212
Query: 330 LAEERRRQNLQEEKERKLE 348
R++ L E++ + E
Sbjct: 213 QERLERQERLDRERQERQE 231
Score = 42.4 bits (98), Expect = 9e-04
Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
E LE + R + RQ++ E R E+ER +RE ER+R + E ++Q++L ER+
Sbjct: 138 EELEIQRRQLQEQQRQKELERERLE-RERMERERLERERLERERLERERLEQEQLERERQ 196
Query: 336 RQNLQEEKERK 346
+ QE ER+
Sbjct: 197 ERERQERLERQ 207
Score = 41.6 bits (96), Expect = 0.001
Identities = 23/77 (29%), Positives = 45/77 (58%), Gaps = 4/77 (5%)
Query: 273 LVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREER----ERKRRKEEEVQQQ 328
L ER+ERE + ++ R++ + L + ++E++ ++R+ER ER R+E +Q+
Sbjct: 161 LERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQE 220
Query: 329 KLAEERRRQNLQEEKER 345
+L ER+ + +E ER
Sbjct: 221 RLDRERQERQERERLER 237
Score = 33.5 bits (75), Expect = 0.40
Identities = 22/88 (25%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Query: 291 QQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER--RRQNLQEEKERKLE 348
Q++ E L+ Q ++ +RE ER+R + E +++++L ER R + QE+ ER+ +
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQ 196
Query: 349 CLPPEPSPDDPESVKIIFKLPNDSRVER 376
+ + E ++ +L R++R
Sbjct: 197 ERERQERLERQERLERQERLERQERLDR 224
Score = 32.0 bits (71), Expect = 1.2
Identities = 24/105 (22%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKE---EEVQQQKLAE 332
E L +E T + Q A + + + +E E ++R+ +E++R+KE E ++++++
Sbjct: 109 EVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMER 168
Query: 333 ERRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERR 377
ER + E + + E L E + + + +L R+ER+
Sbjct: 169 ERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQ 213
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 14/101 (13%)
Query: 273 LVSERLEREERNQTQVLRQQQDEAYLASLRADQ--------------EKERKKREERERK 318
L ERLERE Q Q+ R++Q+ L + ++ER++R+ERER
Sbjct: 176 LERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERL 235
Query: 319 RRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDP 359
R E E Q+++ E+ R+ L+ E+ER++ S + P
Sbjct: 236 ERLERERQERERQEQLEREQLEWERERRISSAAAPASVETP 276
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/79 (30%), Positives = 45/79 (56%)
Query: 270 QTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQK 329
Q L ERLERE + ++ R++ + L R +QE+ ++R+ERER+ R E + + ++
Sbjct: 153 QKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLER 212
Query: 330 LAEERRRQNLQEEKERKLE 348
R++ L E++ + E
Sbjct: 213 QERLERQERLDRERQERQE 231
Score = 42.4 bits (98), Expect = 9e-04
Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
E LE + R + RQ++ E R E+ER +RE ER+R + E ++Q++L ER+
Sbjct: 138 EELEIQRRQLQEQQRQKELERERLE-RERMERERLERERLERERLERERLEQEQLERERQ 196
Query: 336 RQNLQEEKERK 346
+ QE ER+
Sbjct: 197 ERERQERLERQ 207
Score = 41.6 bits (96), Expect = 0.001
Identities = 23/77 (29%), Positives = 45/77 (58%), Gaps = 4/77 (5%)
Query: 273 LVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREER----ERKRRKEEEVQQQ 328
L ER+ERE + ++ R++ + L + ++E++ ++R+ER ER R+E +Q+
Sbjct: 161 LERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQE 220
Query: 329 KLAEERRRQNLQEEKER 345
+L ER+ + +E ER
Sbjct: 221 RLDRERQERQERERLER 237
Score = 33.5 bits (75), Expect = 0.40
Identities = 22/88 (25%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Query: 291 QQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER--RRQNLQEEKERKLE 348
Q++ E L+ Q ++ +RE ER+R + E +++++L ER R + QE+ ER+ +
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQ 196
Query: 349 CLPPEPSPDDPESVKIIFKLPNDSRVER 376
+ + E ++ +L R++R
Sbjct: 197 ERERQERLERQERLERQERLERQERLDR 224
Score = 32.0 bits (71), Expect = 1.2
Identities = 24/105 (22%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKE---EEVQQQKLAE 332
E L +E T + Q A + + + +E E ++R+ +E++R+KE E ++++++
Sbjct: 109 EVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMER 168
Query: 333 ERRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERR 377
ER + E + + E L E + + + +L R+ER+
Sbjct: 169 ERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQ 213
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
b [Homo sapiens]
Length = 1524
Score = 49.3 bits (116), Expect = 7e-06
Identities = 39/167 (23%), Positives = 81/167 (48%), Gaps = 16/167 (9%)
Query: 254 QPDDLINQLTFIMDANQTYLVSERLEREERNQTQV-----LRQQQDEAYLASLRADQEKE 308
Q D++ N+ T ++ ++L ++E ++ L++++ +A A + ++KE
Sbjct: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
Query: 309 RKKREER----ERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPESVKI 364
+K+ E + E + +K+EE ++ K+ E+ R+ L+EEK + +E L P +
Sbjct: 347 KKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDD 406
Query: 365 IFKLPNDSRVERRFH---FSQSLTVIHDFLFSLKESPEKFQIEANFP 408
+ +LP + V+ R F +L V+ L E F ++ FP
Sbjct: 407 LKELPEPTPVKTRLPPEIFGDALMVLE----FLNAFGELFDLQDEFP 449
Score = 35.8 bits (81), Expect = 0.081
Identities = 15/58 (25%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 288 VLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKER 345
+LRQ + E L+A+Q ++ ++ ++RKEE++++Q+ + +++ L+E+++R
Sbjct: 608 ILRQAKQE--FRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQR 663
Score = 32.7 bits (73), Expect = 0.68
Identities = 16/52 (30%), Positives = 32/52 (61%)
Query: 295 EAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERK 346
E Y+ LR +++ R+ + E+ RK R+E + +K EE+ ++ Q+ KE++
Sbjct: 603 EDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQ 654
Score = 30.0 bits (66), Expect = 4.4
Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 7/92 (7%)
Query: 264 FIMDANQTYLVSERLEREERNQTQVLRQQQDEAY----LASLRADQEKERKK---REERE 316
F D T++ S R R ++ Q+D LAS R+ KER K +EE +
Sbjct: 259 FFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMK 318
Query: 317 RKRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
++ +++++K ++ +E+KE+K E
Sbjct: 319 SLAFEKAKLKREKADALEAKKKEKEDKEKKRE 350
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
a [Homo sapiens]
Length = 1556
Score = 49.3 bits (116), Expect = 7e-06
Identities = 39/167 (23%), Positives = 81/167 (48%), Gaps = 16/167 (9%)
Query: 254 QPDDLINQLTFIMDANQTYLVSERLEREERNQTQV-----LRQQQDEAYLASLRADQEKE 308
Q D++ N+ T ++ ++L ++E ++ L++++ +A A + ++KE
Sbjct: 287 QEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKEDKE 346
Query: 309 RKKREER----ERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPESVKI 364
+K+ E + E + +K+EE ++ K+ E+ R+ L+EEK + +E L P +
Sbjct: 347 KKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDD 406
Query: 365 IFKLPNDSRVERRFH---FSQSLTVIHDFLFSLKESPEKFQIEANFP 408
+ +LP + V+ R F +L V+ L E F ++ FP
Sbjct: 407 LKELPEPTPVKTRLPPEIFGDALMVLE----FLNAFGELFDLQDEFP 449
Score = 35.8 bits (81), Expect = 0.081
Identities = 15/58 (25%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 288 VLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKER 345
+LRQ + E L+A+Q ++ ++ ++RKEE++++Q+ + +++ L+E+++R
Sbjct: 640 ILRQAKQE--FRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQR 695
Score = 32.7 bits (73), Expect = 0.68
Identities = 16/52 (30%), Positives = 32/52 (61%)
Query: 295 EAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERK 346
E Y+ LR +++ R+ + E+ RK R+E + +K EE+ ++ Q+ KE++
Sbjct: 635 EDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQ 686
Score = 30.0 bits (66), Expect = 4.4
Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 7/92 (7%)
Query: 264 FIMDANQTYLVSERLEREERNQTQVLRQQQDEAY----LASLRADQEKERKK---REERE 316
F D T++ S R R ++ Q+D LAS R+ KER K +EE +
Sbjct: 259 FFPDDPPTFIFSPANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMK 318
Query: 317 RKRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
++ +++++K ++ +E+KE+K E
Sbjct: 319 SLAFEKAKLKREKADALEAKKKEKEDKEKKRE 350
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 48.9 bits (115), Expect = 9e-06
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 11/108 (10%)
Query: 282 ERNQTQVLRQQQDEAYLA--SLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNL 339
E + + L+Q+Q EA L L+ +E+ RK EE E++R++EE +KL EE ++ L
Sbjct: 286 ESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA--DRKLREEEEKRRL 343
Query: 340 QEEKER-------KLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHF 380
+EE ER K + +P + DD + K + ++E R F
Sbjct: 344 KEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEF 391
Score = 33.5 bits (75), Expect = 0.40
Identities = 20/77 (25%), Positives = 42/77 (54%), Gaps = 5/77 (6%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
+REER + +Q+ + A + +E+E+++ +E +RR E ++QK+ E+
Sbjct: 310 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPED----G 365
Query: 339 LQEEKERKLECLPPEPS 355
L ++K + +C P+ S
Sbjct: 366 LSDDK-KPFKCFTPKGS 381
Score = 33.1 bits (74), Expect = 0.52
Identities = 41/162 (25%), Positives = 64/162 (39%), Gaps = 31/162 (19%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQ----------EKERKKREERERKRRKEEEVQQQ 328
ER R + + LRQ+Q+E L + DQ ++E K + +E +
Sbjct: 34 ERRRRARQERLRQKQEEESLGQV-TDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLE 92
Query: 329 KLA--EERRRQNLQEEKERKLE----------CLPPEPSPDDPESVKIIFKLPNDSRVER 376
+LA EERR++ LQE ER+ E LP +D + K +
Sbjct: 93 RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE 152
Query: 377 RFHFSQSLTVI--------HDFLFSLKESPEKFQIEANFPRR 410
R+ ++ TV D + KE EK + E P+R
Sbjct: 153 RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 194
Score = 33.1 bits (74), Expect = 0.52
Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 281 EERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQ 340
E + + LR+++ E ++K+++ E E ++K EE ++K+ EE ++ Q
Sbjct: 270 EAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE--RRKVLEEEEQRRKQ 327
Query: 341 EEKERKL 347
EE +RKL
Sbjct: 328 EEADRKL 334
Score = 32.0 bits (71), Expect = 1.2
Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 10/117 (8%)
Query: 254 QPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKR- 312
Q ++ + Q+T ++ N V + + TQV + DEA A +E+ R+KR
Sbjct: 48 QEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV--EGDDEAAFLERLARREERRQKRL 105
Query: 313 -EERERKRRKEEEVQQQKLAEERRR------QNLQEEKERKLECLPPEPSPDDPESV 362
E ER++ + + L+ RR +N EKE K E ++ E+V
Sbjct: 106 QEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETV 162
Score = 32.0 bits (71), Expect = 1.2
Identities = 17/79 (21%), Positives = 46/79 (58%), Gaps = 5/79 (6%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRAD----QEKERKKREERERKRRKEEEVQQQKL 330
+E E+EE+++++ R + +E + ++ E K+E++E++ +EE+ ++ +
Sbjct: 138 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
Query: 331 AEER-RRQNLQEEKERKLE 348
E + + + ++++KE K E
Sbjct: 198 GENQIKDEKIKKDKEPKEE 216
Score = 30.4 bits (67), Expect = 3.4
Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 286 TQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKER 345
+Q+ Q+ D+ A +E+ R+ R+ER R++++EE + Q E QN ++E
Sbjct: 17 SQIAYQRNDDD---EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEA 73
Query: 346 KLECLPPEPSPDD 358
K + DD
Sbjct: 74 KTTTTNTQVEGDD 86
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 48.9 bits (115), Expect = 9e-06
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 11/108 (10%)
Query: 282 ERNQTQVLRQQQDEAYLA--SLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNL 339
E + + L+Q+Q EA L L+ +E+ RK EE E++R++EE +KL EE ++ L
Sbjct: 312 ESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA--DRKLREEEEKRRL 369
Query: 340 QEEKER-------KLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHF 380
+EE ER K + +P + DD + K + ++E R F
Sbjct: 370 KEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEF 417
Score = 33.5 bits (75), Expect = 0.40
Identities = 19/85 (22%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
+E E+EE+++++ R + +E + ++ Q+ + + EE +++ +++EE +++K
Sbjct: 138 NETTEKEEKSESRQERYEIEETETVT-KSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS 196
Query: 335 RRQNLQEEKERKLECLPPEPSPDDP 359
+N EEK K++ + D P
Sbjct: 197 IGENQGEEKGTKVQAKREKLQEDKP 221
Score = 33.5 bits (75), Expect = 0.40
Identities = 20/77 (25%), Positives = 42/77 (54%), Gaps = 5/77 (6%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
+REER + +Q+ + A + +E+E+++ +E +RR E ++QK+ E+
Sbjct: 336 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPED----G 391
Query: 339 LQEEKERKLECLPPEPS 355
L ++K + +C P+ S
Sbjct: 392 LSDDK-KPFKCFTPKGS 407
Score = 33.1 bits (74), Expect = 0.52
Identities = 41/162 (25%), Positives = 64/162 (39%), Gaps = 31/162 (19%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQ----------EKERKKREERERKRRKEEEVQQQ 328
ER R + + LRQ+Q+E L + DQ ++E K + +E +
Sbjct: 34 ERRRRARQERLRQKQEEESLGQV-TDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLE 92
Query: 329 KLA--EERRRQNLQEEKERKLE----------CLPPEPSPDDPESVKIIFKLPNDSRVER 376
+LA EERR++ LQE ER+ E LP +D + K +
Sbjct: 93 RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE 152
Query: 377 RFHFSQSLTVI--------HDFLFSLKESPEKFQIEANFPRR 410
R+ ++ TV D + KE EK + E P+R
Sbjct: 153 RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 194
Score = 33.1 bits (74), Expect = 0.52
Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 281 EERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQ 340
E + + LR+++ E ++K+++ E E ++K EE ++K+ EE ++ Q
Sbjct: 296 EAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE--RRKVLEEEEQRRKQ 353
Query: 341 EEKERKL 347
EE +RKL
Sbjct: 354 EEADRKL 360
Score = 32.0 bits (71), Expect = 1.2
Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 10/117 (8%)
Query: 254 QPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKR- 312
Q ++ + Q+T ++ N V + + TQV + DEA A +E+ R+KR
Sbjct: 48 QEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV--EGDDEAAFLERLARREERRQKRL 105
Query: 313 -EERERKRRKEEEVQQQKLAEERRR------QNLQEEKERKLECLPPEPSPDDPESV 362
E ER++ + + L+ RR +N EKE K E ++ E+V
Sbjct: 106 QEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETV 162
Score = 30.4 bits (67), Expect = 3.4
Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 286 TQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKER 345
+Q+ Q+ D+ A +E+ R+ R+ER R++++EE + Q E QN ++E
Sbjct: 17 SQIAYQRNDDD---EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEA 73
Query: 346 KLECLPPEPSPDD 358
K + DD
Sbjct: 74 KTTTTNTQVEGDD 86
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 48.9 bits (115), Expect = 9e-06
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 11/108 (10%)
Query: 282 ERNQTQVLRQQQDEAYLA--SLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNL 339
E + + L+Q+Q EA L L+ +E+ RK EE E++R++EE +KL EE ++ L
Sbjct: 318 ESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA--DRKLREEEEKRRL 375
Query: 340 QEEKER-------KLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHF 380
+EE ER K + +P + DD + K + ++E R F
Sbjct: 376 KEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEF 423
Score = 33.5 bits (75), Expect = 0.40
Identities = 19/85 (22%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
+E E+EE+++++ R + +E + ++ Q+ + + EE +++ +++EE +++K
Sbjct: 144 NETTEKEEKSESRQERYEIEETETVT-KSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS 202
Query: 335 RRQNLQEEKERKLECLPPEPSPDDP 359
+N EEK K++ + D P
Sbjct: 203 IGENQGEEKGTKVQAKREKLQEDKP 227
Score = 33.5 bits (75), Expect = 0.40
Identities = 20/77 (25%), Positives = 42/77 (54%), Gaps = 5/77 (6%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
+REER + +Q+ + A + +E+E+++ +E +RR E ++QK+ E+
Sbjct: 342 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPED----G 397
Query: 339 LQEEKERKLECLPPEPS 355
L ++K + +C P+ S
Sbjct: 398 LSDDK-KPFKCFTPKGS 413
Score = 33.1 bits (74), Expect = 0.52
Identities = 41/162 (25%), Positives = 64/162 (39%), Gaps = 31/162 (19%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQ----------EKERKKREERERKRRKEEEVQQQ 328
ER R + + LRQ+Q+E L + DQ ++E K + +E +
Sbjct: 40 ERRRRARQERLRQKQEEESLGQV-TDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLE 98
Query: 329 KLA--EERRRQNLQEEKERKLE----------CLPPEPSPDDPESVKIIFKLPNDSRVER 376
+LA EERR++ LQE ER+ E LP +D + K +
Sbjct: 99 RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE 158
Query: 377 RFHFSQSLTVI--------HDFLFSLKESPEKFQIEANFPRR 410
R+ ++ TV D + KE EK + E P+R
Sbjct: 159 RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Score = 33.1 bits (74), Expect = 0.52
Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 281 EERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQ 340
E + + LR+++ E ++K+++ E E ++K EE ++K+ EE ++ Q
Sbjct: 302 EAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE--RRKVLEEEEQRRKQ 359
Query: 341 EEKERKL 347
EE +RKL
Sbjct: 360 EEADRKL 366
Score = 32.0 bits (71), Expect = 1.2
Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 10/117 (8%)
Query: 254 QPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKR- 312
Q ++ + Q+T ++ N V + + TQV + DEA A +E+ R+KR
Sbjct: 54 QEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV--EGDDEAAFLERLARREERRQKRL 111
Query: 313 -EERERKRRKEEEVQQQKLAEERRR------QNLQEEKERKLECLPPEPSPDDPESV 362
E ER++ + + L+ RR +N EKE K E ++ E+V
Sbjct: 112 QEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETV 168
Score = 30.4 bits (67), Expect = 3.4
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 5/79 (6%)
Query: 280 REERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNL 339
R E + R DE A +E+ R+ R+ER R++++EE + Q E QN
Sbjct: 19 RLEAERIAYQRNDDDEE-----EAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNS 73
Query: 340 QEEKERKLECLPPEPSPDD 358
++E K + DD
Sbjct: 74 VPDEEAKTTTTNTQVEGDD 92
Score = 29.6 bits (65), Expect = 5.8
Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 287 QVLRQQQDEAYLASLRADQEKERKKREE--RERKRRKEEEVQQQKLAEERRRQNLQEEKE 344
++ RQ+++E L + R ++ EE RER+RR +E +QK EE Q + +
Sbjct: 9 ELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEV 68
Query: 345 RKLECLPPE 353
+P E
Sbjct: 69 NAQNSVPDE 77
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 48.9 bits (115), Expect = 9e-06
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 11/108 (10%)
Query: 282 ERNQTQVLRQQQDEAYLA--SLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNL 339
E + + L+Q+Q EA L L+ +E+ RK EE E++R++EE +KL EE ++ L
Sbjct: 292 ESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA--DRKLREEEEKRRL 349
Query: 340 QEEKER-------KLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHF 380
+EE ER K + +P + DD + K + ++E R F
Sbjct: 350 KEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEF 397
Score = 33.5 bits (75), Expect = 0.40
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 8/83 (9%)
Query: 273 LVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAE 332
L +R ER + + + R++Q+EA LR ++EK R K EE ER RR E ++QK+ E
Sbjct: 313 LKKKREERRKVLEEEEQRRKQEEAD-RKLREEEEKRRLK-EEIER-RRAEAAEKRQKMPE 369
Query: 333 ERRRQNLQEEKERKLECLPPEPS 355
+ L ++K + +C P+ S
Sbjct: 370 D----GLSDDK-KPFKCFTPKGS 387
Score = 33.1 bits (74), Expect = 0.52
Identities = 41/162 (25%), Positives = 64/162 (39%), Gaps = 31/162 (19%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQ----------EKERKKREERERKRRKEEEVQQQ 328
ER R + + LRQ+Q+E L + DQ ++E K + +E +
Sbjct: 40 ERRRRARQERLRQKQEEESLGQV-TDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLE 98
Query: 329 KLA--EERRRQNLQEEKERKLE----------CLPPEPSPDDPESVKIIFKLPNDSRVER 376
+LA EERR++ LQE ER+ E LP +D + K +
Sbjct: 99 RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE 158
Query: 377 RFHFSQSLTVI--------HDFLFSLKESPEKFQIEANFPRR 410
R+ ++ TV D + KE EK + E P+R
Sbjct: 159 RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Score = 33.1 bits (74), Expect = 0.52
Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 281 EERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQ 340
E + + LR+++ E ++K+++ E E ++K EE ++K+ EE ++ Q
Sbjct: 276 EAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE--RRKVLEEEEQRRKQ 333
Query: 341 EEKERKL 347
EE +RKL
Sbjct: 334 EEADRKL 340
Score = 32.0 bits (71), Expect = 1.2
Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 10/117 (8%)
Query: 254 QPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKR- 312
Q ++ + Q+T ++ N V + + TQV + DEA A +E+ R+KR
Sbjct: 54 QEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV--EGDDEAAFLERLARREERRQKRL 111
Query: 313 -EERERKRRKEEEVQQQKLAEERRR------QNLQEEKERKLECLPPEPSPDDPESV 362
E ER++ + + L+ RR +N EKE K E ++ E+V
Sbjct: 112 QEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETV 168
Score = 32.0 bits (71), Expect = 1.2
Identities = 17/79 (21%), Positives = 46/79 (58%), Gaps = 5/79 (6%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRAD----QEKERKKREERERKRRKEEEVQQQKL 330
+E E+EE+++++ R + +E + ++ E K+E++E++ +EE+ ++ +
Sbjct: 144 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 203
Query: 331 AEER-RRQNLQEEKERKLE 348
E + + + ++++KE K E
Sbjct: 204 GENQIKDEKIKKDKEPKEE 222
Score = 30.4 bits (67), Expect = 3.4
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 5/79 (6%)
Query: 280 REERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNL 339
R E + R DE A +E+ R+ R+ER R++++EE + Q E QN
Sbjct: 19 RLEAERIAYQRNDDDEE-----EAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNS 73
Query: 340 QEEKERKLECLPPEPSPDD 358
++E K + DD
Sbjct: 74 VPDEEAKTTTTNTQVEGDD 92
Score = 29.6 bits (65), Expect = 5.8
Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 287 QVLRQQQDEAYLASLRADQEKERKKREE--RERKRRKEEEVQQQKLAEERRRQNLQEEKE 344
++ RQ+++E L + R ++ EE RER+RR +E +QK EE Q + +
Sbjct: 9 ELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEV 68
Query: 345 RKLECLPPE 353
+P E
Sbjct: 69 NAQNSVPDE 77
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 48.9 bits (115), Expect = 9e-06
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 11/108 (10%)
Query: 282 ERNQTQVLRQQQDEAYLA--SLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNL 339
E + + L+Q+Q EA L L+ +E+ RK EE E++R++EE +KL EE ++ L
Sbjct: 547 ESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA--DRKLREEEEKRRL 604
Query: 340 QEEKER-------KLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHF 380
+EE ER K + +P + DD + K + ++E R F
Sbjct: 605 KEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEF 652
Score = 46.6 bits (109), Expect = 5e-05
Identities = 26/73 (35%), Positives = 44/73 (60%), Gaps = 3/73 (4%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
ER+ EE+ + ++ ++E A+ + KE +KR ER+R KEEE ++ AEER+
Sbjct: 315 ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEE---KRAAEERQ 371
Query: 336 RQNLQEEKERKLE 348
R +EE++ K+E
Sbjct: 372 RARAEEEEKAKVE 384
Score = 44.7 bits (104), Expect = 2e-04
Identities = 27/89 (30%), Positives = 49/89 (55%), Gaps = 7/89 (7%)
Query: 267 DANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEV- 325
+A + L +E ER + Q + + ++ A QE+ER++ EERER R +E+
Sbjct: 266 EAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAA 325
Query: 326 -QQQKLAEERRR-----QNLQEEKERKLE 348
++Q++ EE +R Q ++EE++R E
Sbjct: 326 EERQRIKEEEKRAAEERQRIKEEEKRAAE 354
Score = 44.3 bits (103), Expect = 2e-04
Identities = 21/73 (28%), Positives = 43/73 (58%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
+R++ EE+ + ++ ++E A+ + KE +KR ER+R + EE ++ K+ E++R
Sbjct: 329 QRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKR 388
Query: 336 RQNLQEEKERKLE 348
+ L+E+K E
Sbjct: 389 NKQLEEKKHAMQE 401
Score = 39.3 bits (90), Expect = 0.007
Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 23/91 (25%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEK------------------ERKKREERER 317
E++E E++ + + R + + ++A+Q+K ER++RE ER
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER 314
Query: 318 KRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
+R +EEE ++ AEER+R ++EE++R E
Sbjct: 315 ERMREEE---KRAAEERQR--IKEEEKRAAE 340
Score = 33.5 bits (75), Expect = 0.40
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 8/83 (9%)
Query: 273 LVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAE 332
L +R ER + + + R++Q+EA LR ++EK R K EE ER RR E ++QK+ E
Sbjct: 568 LKKKREERRKVLEEEEQRRKQEEAD-RKLREEEEKRRLK-EEIER-RRAEAAEKRQKMPE 624
Query: 333 ERRRQNLQEEKERKLECLPPEPS 355
+ L ++K + +C P+ S
Sbjct: 625 D----GLSDDK-KPFKCFTPKGS 642
Score = 33.1 bits (74), Expect = 0.52
Identities = 41/162 (25%), Positives = 64/162 (39%), Gaps = 31/162 (19%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQ----------EKERKKREERERKRRKEEEVQQQ 328
ER R + + LRQ+Q+E L + DQ ++E K + +E +
Sbjct: 40 ERRRRARQERLRQKQEEESLGQV-TDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLE 98
Query: 329 KLA--EERRRQNLQEEKERKLE----------CLPPEPSPDDPESVKIIFKLPNDSRVER 376
+LA EERR++ LQE ER+ E LP +D + K +
Sbjct: 99 RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE 158
Query: 377 RFHFSQSLTVI--------HDFLFSLKESPEKFQIEANFPRR 410
R+ ++ TV D + KE EK + E P+R
Sbjct: 159 RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Score = 33.1 bits (74), Expect = 0.52
Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 281 EERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQ 340
E + + LR+++ E ++K+++ E E ++K EE ++K+ EE ++ Q
Sbjct: 531 EAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE--RRKVLEEEEQRRKQ 588
Query: 341 EEKERKL 347
EE +RKL
Sbjct: 589 EEADRKL 595
Score = 32.3 bits (72), Expect = 0.89
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 12/84 (14%)
Query: 273 LVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREE-----RERKRRKEEEVQQ 327
L + ++ EE Q + Q DE +++KER + E ER+R K E Q
Sbjct: 228 LKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAE--QD 285
Query: 328 QKLAEERRRQNLQE-----EKERK 346
+K+A+ER R +E E+ER+
Sbjct: 286 KKIADERARIEAEEKAAAQERERR 309
Score = 32.0 bits (71), Expect = 1.2
Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 10/117 (8%)
Query: 254 QPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKR- 312
Q ++ + Q+T ++ N V + + TQV + DEA A +E+ R+KR
Sbjct: 54 QEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV--EGDDEAAFLERLARREERRQKRL 111
Query: 313 -EERERKRRKEEEVQQQKLAEERRR------QNLQEEKERKLECLPPEPSPDDPESV 362
E ER++ + + L+ RR +N EKE K E ++ E+V
Sbjct: 112 QEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETV 168
Score = 32.0 bits (71), Expect = 1.2
Identities = 20/80 (25%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Query: 269 NQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQ 328
NQ ++ E E + +T V+ + + ++S QE+ER++ + K EE ++
Sbjct: 206 NQVEVMVEEKTTESQEETVVMSLKNGQ--ISSEEPKQEEEREQGSDEISHHEKMEEEDKE 263
Query: 329 KLAEERRRQNLQEEKERKLE 348
+ ER R +E + K E
Sbjct: 264 RAEAERARLEAEERERIKAE 283
Score = 32.0 bits (71), Expect = 1.2
Identities = 17/70 (24%), Positives = 43/70 (61%), Gaps = 1/70 (1%)
Query: 274 VSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEE 333
V+E+ +E++ QT VL++Q +E ++A +EK ++ + +++ K+E++++ K +E
Sbjct: 418 VNEKKAQEDKLQTAVLKKQGEEKG-TKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 476
Query: 334 RRRQNLQEEK 343
+ + +K
Sbjct: 477 EVKSFMDRKK 486
Score = 31.6 bits (70), Expect = 1.5
Identities = 19/73 (26%), Positives = 41/73 (56%), Gaps = 5/73 (6%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
+R++ EE+ + ++ ++E RA +E++R + EE E K + EE+ + ++L E++
Sbjct: 343 QRIKEEEKRAAEERQRIKEE----EKRAAEERQRARAEEEE-KAKVEEQKRNKQLEEKKH 397
Query: 336 RQNLQEEKERKLE 348
+ K K+E
Sbjct: 398 AMQETKIKGEKVE 410
Score = 30.4 bits (67), Expect = 3.4
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 5/79 (6%)
Query: 280 REERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNL 339
R E + R DE A +E+ R+ R+ER R++++EE + Q E QN
Sbjct: 19 RLEAERIAYQRNDDDEE-----EAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNS 73
Query: 340 QEEKERKLECLPPEPSPDD 358
++E K + DD
Sbjct: 74 VPDEEAKTTTTNTQVEGDD 92
Score = 29.6 bits (65), Expect = 5.8
Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 287 QVLRQQQDEAYLASLRADQEKERKKREE--RERKRRKEEEVQQQKLAEERRRQNLQEEKE 344
++ RQ+++E L + R ++ EE RER+RR +E +QK EE Q + +
Sbjct: 9 ELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEV 68
Query: 345 RKLECLPPE 353
+P E
Sbjct: 69 NAQNSVPDE 77
Score = 29.3 bits (64), Expect = 7.5
Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 277 RLEREERNQTQVLRQ--QQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
R ER E +T+ + + Q+++ A ++KE+++ EE + KR E Q + + EE+
Sbjct: 156 RQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEK 215
Query: 335 RRQNLQE 341
++ +E
Sbjct: 216 TTESQEE 222
Score = 28.9 bits (63), Expect = 9.9
Identities = 15/78 (19%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRADQ----EKERKKREERERKRRKEEEVQQQKL 330
+E E+EE+++++ R + +E + + + E K+E++E++ +EE+ ++ +
Sbjct: 144 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 203
Query: 331 AEERRRQNLQEEKERKLE 348
E + ++E+ E
Sbjct: 204 GENQVEVMVEEKTTESQE 221
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 48.5 bits (114), Expect = 1e-05
Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREER--ERKRRKEEEVQQQKLAEE 333
ER ER Q R+++ E R +E+ER++ ER ER+RRKEE +++ +E
Sbjct: 403 ERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDE 462
Query: 334 RRRQNLQEEKERKLECLPPEPSPDDPE 360
+ RQ+ ++E++ E +P P P+
Sbjct: 463 KDRQHRDRDREKEREKEKGKPKPRSPQ 489
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 9/86 (10%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
ER ER++ + RQ++ E R D+E++R+K EE ER+R K +E ++R+
Sbjct: 416 ERERERERDRERERRQREREREREHER-DKERQRRK-EEWERERAKRDE-------KDRQ 466
Query: 336 RQNLQEEKERKLECLPPEPSPDDPES 361
++ EKER+ E P+P P S
Sbjct: 467 HRDRDREKEREKEKGKPKPRSPQPPS 492
Score = 40.0 bits (92), Expect = 0.004
Identities = 19/69 (27%), Positives = 42/69 (60%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRR 336
R++ E R+++ E + + ++E+ER++ ERER++R+ E ++ + +ER+R
Sbjct: 389 RVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQR 448
Query: 337 QNLQEEKER 345
+ + E+ER
Sbjct: 449 RKEEWERER 457
Score = 37.0 bits (84), Expect = 0.036
Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKRE---ERERKRRKEEEVQQQKLAE 332
ER R + + ++ + E Y ++E+ER+ R+ ERER+R +E E +Q++
Sbjct: 377 ERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQRERER 436
Query: 333 ERRRQNLQEEKERKLE 348
ER + +E + RK E
Sbjct: 437 EREHERDKERQRRKEE 452
Score = 32.0 bits (71), Expect = 1.2
Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQE--KERKKREERERKRRKEEEVQQQKLAEE 333
ER ER Q + R+++ E R +E +ER KR+E++R+ R + ++++ +
Sbjct: 422 ERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKG 481
Query: 334 RRRQNLQEEKERKLECLPPEPSPDDPE 360
+ + + R+ E E + P+
Sbjct: 482 KPKPRSPQPPSRQAEPPKKEAATTGPQ 508
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/101 (33%), Positives = 58/101 (57%), Gaps = 9/101 (8%)
Query: 248 RLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEK 307
R + L+Q L Q + + L++ER +R E+ + Q R ++ + R QE+
Sbjct: 371 RRQQLLQEQQLREQEEY-----KRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQER 425
Query: 308 ERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
E+++RE+ E KRR EE +++K EERRR EE++R++E
Sbjct: 426 EQRRREQ-EEKRRLEELERRRKEEEERRR---AEEEKRRVE 462
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/77 (37%), Positives = 46/77 (59%), Gaps = 5/77 (6%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASL---RADQEKERKKREERERKRRKEEEVQQQKLAEE 333
RLE ++R + + RQQ+ E R +E ER+++EE ER+R +EE+ + ++ E
Sbjct: 408 RLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEY 467
Query: 334 RRRQNLQEEKERKLECL 350
RRQ EE++R LE L
Sbjct: 468 IRRQ--LEEEQRHLEVL 482
Score = 43.1 bits (100), Expect = 5e-04
Identities = 29/76 (38%), Positives = 49/76 (64%), Gaps = 10/76 (13%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKR-----RKEEEVQQQK 329
SE L R++ Q Q LR+Q++ Y L A+++K R ++++ +R+R R+E E ++Q+
Sbjct: 367 SEALRRQQLLQEQQLREQEE--YKRQLLAERQK-RIEQQKEQRRRLEEQQRREREARRQQ 423
Query: 330 LAEERRRQNLQEEKER 345
E+RRR+ QEEK R
Sbjct: 424 EREQRRRE--QEEKRR 437
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 14/108 (12%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASL--RADQEKERKKREERERKRRKEEEVQQQKLAEE 333
ER R ++ + Q R+Q+++ L L R +E+ER++ EE +R+ +E+E +++L EE
Sbjct: 416 EREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEE 475
Query: 334 RR------RQNLQEEKERKLECLPP------EPSPDDPESVKIIFKLP 369
+R +Q LQE+ + P +P P E K F P
Sbjct: 476 QRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAP 523
Score = 38.1 bits (87), Expect = 0.016
Identities = 23/77 (29%), Positives = 45/77 (58%), Gaps = 6/77 (7%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEE-----VQQQKLA 331
RL++E + +++ LR+QQ LR +E +R+ ER+++ +++E +QQ+
Sbjct: 358 RLQQENKERSEALRRQQ-LLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRRE 416
Query: 332 EERRRQNLQEEKERKLE 348
E RRQ +E++ R+ E
Sbjct: 417 REARRQQEREQRRREQE 433
Score = 29.6 bits (65), Expect = 5.8
Identities = 14/51 (27%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
Query: 299 ASLRADQEKERKKREERERKRRKEEEVQQQKLAE-ERRRQNLQEEKERKLE 348
++LR D + +++ +ER R+++ +Q+Q+L E E ++ L E+++++E
Sbjct: 350 STLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIE 400
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/101 (33%), Positives = 58/101 (57%), Gaps = 9/101 (8%)
Query: 248 RLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEK 307
R + L+Q L Q + + L++ER +R E+ + Q R ++ + R QE+
Sbjct: 371 RRQQLLQEQQLREQEEY-----KRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQER 425
Query: 308 ERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
E+++RE+ E KRR EE +++K EERRR EE++R++E
Sbjct: 426 EQRRREQ-EEKRRLEELERRRKEEEERRR---AEEEKRRVE 462
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/77 (37%), Positives = 46/77 (59%), Gaps = 5/77 (6%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASL---RADQEKERKKREERERKRRKEEEVQQQKLAEE 333
RLE ++R + + RQQ+ E R +E ER+++EE ER+R +EE+ + ++ E
Sbjct: 408 RLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEY 467
Query: 334 RRRQNLQEEKERKLECL 350
RRQ EE++R LE L
Sbjct: 468 IRRQ--LEEEQRHLEVL 482
Score = 43.1 bits (100), Expect = 5e-04
Identities = 29/76 (38%), Positives = 49/76 (64%), Gaps = 10/76 (13%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKR-----RKEEEVQQQK 329
SE L R++ Q Q LR+Q++ Y L A+++K R ++++ +R+R R+E E ++Q+
Sbjct: 367 SEALRRQQLLQEQQLREQEE--YKRQLLAERQK-RIEQQKEQRRRLEEQQRREREARRQQ 423
Query: 330 LAEERRRQNLQEEKER 345
E+RRR+ QEEK R
Sbjct: 424 EREQRRRE--QEEKRR 437
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 14/108 (12%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASL--RADQEKERKKREERERKRRKEEEVQQQKLAEE 333
ER R ++ + Q R+Q+++ L L R +E+ER++ EE +R+ +E+E +++L EE
Sbjct: 416 EREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEE 475
Query: 334 RR------RQNLQEEKERKLECLPP------EPSPDDPESVKIIFKLP 369
+R +Q LQE+ + P +P P E K F P
Sbjct: 476 QRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAP 523
Score = 38.1 bits (87), Expect = 0.016
Identities = 23/77 (29%), Positives = 45/77 (58%), Gaps = 6/77 (7%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEE-----VQQQKLA 331
RL++E + +++ LR+QQ LR +E +R+ ER+++ +++E +QQ+
Sbjct: 358 RLQQENKERSEALRRQQ-LLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRRE 416
Query: 332 EERRRQNLQEEKERKLE 348
E RRQ +E++ R+ E
Sbjct: 417 REARRQQEREQRRREQE 433
Score = 29.6 bits (65), Expect = 5.8
Identities = 14/51 (27%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
Query: 299 ASLRADQEKERKKREERERKRRKEEEVQQQKLAE-ERRRQNLQEEKERKLE 348
++LR D + +++ +ER R+++ +Q+Q+L E E ++ L E+++++E
Sbjct: 350 STLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIE 400
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/101 (33%), Positives = 58/101 (57%), Gaps = 9/101 (8%)
Query: 248 RLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEK 307
R + L+Q L Q + + L++ER +R E+ + Q R ++ + R QE+
Sbjct: 371 RRQQLLQEQQLREQEEY-----KRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQER 425
Query: 308 ERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
E+++RE+ E KRR EE +++K EERRR EE++R++E
Sbjct: 426 EQRRREQ-EEKRRLEELERRRKEEEERRR---AEEEKRRVE 462
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/77 (37%), Positives = 46/77 (59%), Gaps = 5/77 (6%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASL---RADQEKERKKREERERKRRKEEEVQQQKLAEE 333
RLE ++R + + RQQ+ E R +E ER+++EE ER+R +EE+ + ++ E
Sbjct: 408 RLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEY 467
Query: 334 RRRQNLQEEKERKLECL 350
RRQ EE++R LE L
Sbjct: 468 IRRQ--LEEEQRHLEVL 482
Score = 43.1 bits (100), Expect = 5e-04
Identities = 29/79 (36%), Positives = 49/79 (62%), Gaps = 11/79 (13%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
SE L R++ Q Q LR+Q++ Y L A ER+KR E+++++R+ E QQ++ E R
Sbjct: 367 SEALRRQQLLQEQQLREQEE--YKRQLLA----ERQKRIEQQKEQRRRLEEQQRREREAR 420
Query: 335 RRQ-----NLQEEKERKLE 348
R+Q ++E++R+LE
Sbjct: 421 RQQEREQRRREQEEKRRLE 439
Score = 42.4 bits (98), Expect = 9e-04
Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 7/81 (8%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQ--QQKLAEE 333
ER R ++ + Q R+Q+++ L L +++E ++R E KRR E E + +++L EE
Sbjct: 416 EREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEE 475
Query: 334 RR-----RQNLQEEKERKLEC 349
+R +Q L +E+ LEC
Sbjct: 476 QRHLEVLQQQLLQEQAMLLEC 496
Score = 38.1 bits (87), Expect = 0.016
Identities = 23/77 (29%), Positives = 45/77 (58%), Gaps = 6/77 (7%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEE-----VQQQKLA 331
RL++E + +++ LR+QQ LR +E +R+ ER+++ +++E +QQ+
Sbjct: 358 RLQQENKERSEALRRQQ-LLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRRE 416
Query: 332 EERRRQNLQEEKERKLE 348
E RRQ +E++ R+ E
Sbjct: 417 REARRQQEREQRRREQE 433
Score = 33.1 bits (74), Expect = 0.52
Identities = 22/79 (27%), Positives = 43/79 (54%), Gaps = 12/79 (15%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEE-----------V 325
R E+EE+ + + L +++ E RA++EK R +RE+ +R+ EEE +
Sbjct: 429 RREQEEKRRLEELERRRKEEE-ERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL 487
Query: 326 QQQKLAEERRRQNLQEEKE 344
Q+Q + E R + ++E ++
Sbjct: 488 QEQAMLLECRWREMEEHRQ 506
Score = 30.4 bits (67), Expect = 3.4
Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 34/184 (18%)
Query: 266 MDANQTYLVSERLEREERNQTQVLRQQ--QDEAYLASLRADQEKERKKREERERKRRKEE 323
++ Q Y + +LE E+R+ +VL+QQ Q++A L R + +E R+ E
Sbjct: 461 VEREQEY-IRRQLEEEQRH-LEVLQQQLLQEQAMLLECRWREMEEH----------RQAE 508
Query: 324 EVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDS----------R 373
+Q+Q E+ +LQ + R +P P E K F P
Sbjct: 509 RLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRARE 568
Query: 374 VERRF----HFS------QSLTVIHDFLFSLKESPEKFQIEANFPRRVLPCIPSEEWPNP 423
VE RF H S Q+ V+ + S ES E+ P P P +W +
Sbjct: 569 VEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVQWSHL 628
Query: 424 PTLQ 427
+L+
Sbjct: 629 ASLK 632
Score = 29.6 bits (65), Expect = 5.8
Identities = 14/51 (27%), Positives = 34/51 (66%), Gaps = 1/51 (1%)
Query: 299 ASLRADQEKERKKREERERKRRKEEEVQQQKLAE-ERRRQNLQEEKERKLE 348
++LR D + +++ +ER R+++ +Q+Q+L E E ++ L E+++++E
Sbjct: 350 STLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIE 400
>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
sapiens]
Length = 528
Score = 47.8 bits (112), Expect = 2e-05
Identities = 29/84 (34%), Positives = 55/84 (65%), Gaps = 11/84 (13%)
Query: 271 TYLVSERLEREE----RNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQ 326
TY+ S ++E+EE R + + R++++E R +E+E+++REE ER RR+EEE
Sbjct: 174 TYVASHKIEKEEQEKKRKEEEERRRREEEE---RERLQKEEEKRRREEEERLRREEEE-- 228
Query: 327 QQKLAEERRRQNLQEEKERKLECL 350
++++ EER R L+++K++ + L
Sbjct: 229 RRRIEEERLR--LEQQKQQIMAAL 250
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 47.4 bits (111), Expect = 3e-05
Identities = 26/70 (37%), Positives = 45/70 (64%), Gaps = 7/70 (10%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKK-REERERKRRKEEEVQQQKLAEERR 335
R EE ++ + L++++ E R ++EKER++ REERERKRR+EEE ++++ A +R
Sbjct: 235 RKRTEEPDRDERLKKEKQE------REEREKEREREREERERKRRREEEEREKERARDRE 288
Query: 336 RQNLQEEKER 345
R+ + R
Sbjct: 289 RRKRSRSRSR 298
Score = 38.5 bits (88), Expect = 0.012
Identities = 16/44 (36%), Positives = 32/44 (72%)
Query: 305 QEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
+E +R +R ++E++ R+E E ++++ EER R+ +EE+ER+ E
Sbjct: 239 EEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKE 282
Score = 37.4 bits (85), Expect = 0.028
Identities = 20/71 (28%), Positives = 40/71 (56%), Gaps = 8/71 (11%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
E L+ + R +T+ +DE R +EK+ ++ E+ER+R +EE ++++ EE R
Sbjct: 228 EELKEKLRKRTE--EPDRDE------RLKKEKQEREEREKEREREREERERKRRREEEER 279
Query: 336 RQNLQEEKERK 346
+ ++ER+
Sbjct: 280 EKERARDRERR 290
Score = 37.4 bits (85), Expect = 0.028
Identities = 18/74 (24%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 273 LVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAE 332
L E+ EREER + + ++++E R ++E+E+++ +RER++R +
Sbjct: 247 LKKEKQEREEREKER--EREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTS 304
Query: 333 ERRRQNLQEEKERK 346
+RR ++ K +
Sbjct: 305 DRRCSRSRDHKRSR 318
Score = 30.4 bits (67), Expect = 3.4
Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 277 RLEREERNQTQVL-RQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
R E EER + + R+++ + S + + +R+ R+ KR + E +++ + +RR
Sbjct: 273 RREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRE-RRRSRSRDRR 331
Query: 336 RQNLQEEKERK 346
R + ERK
Sbjct: 332 RSRSHDRSERK 342
Score = 29.3 bits (64), Expect = 7.5
Identities = 18/89 (20%), Positives = 39/89 (43%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
S+R R+ + +++ + R + +R +R+ R R R + + + + +
Sbjct: 304 SDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKH 363
Query: 335 RRQNLQEEKERKLECLPPEPSPDDPESVK 363
R ++ E++RK + S D SVK
Sbjct: 364 RSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 47.4 bits (111), Expect = 3e-05
Identities = 26/70 (37%), Positives = 45/70 (64%), Gaps = 7/70 (10%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKK-REERERKRRKEEEVQQQKLAEERR 335
R EE ++ + L++++ E R ++EKER++ REERERKRR+EEE ++++ A +R
Sbjct: 235 RKRTEEPDRDERLKKEKQE------REEREKEREREREERERKRRREEEEREKERARDRE 288
Query: 336 RQNLQEEKER 345
R+ + R
Sbjct: 289 RRKRSRSRSR 298
Score = 38.5 bits (88), Expect = 0.012
Identities = 16/44 (36%), Positives = 32/44 (72%)
Query: 305 QEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
+E +R +R ++E++ R+E E ++++ EER R+ +EE+ER+ E
Sbjct: 239 EEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKE 282
Score = 37.4 bits (85), Expect = 0.028
Identities = 20/71 (28%), Positives = 40/71 (56%), Gaps = 8/71 (11%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
E L+ + R +T+ +DE R +EK+ ++ E+ER+R +EE ++++ EE R
Sbjct: 228 EELKEKLRKRTE--EPDRDE------RLKKEKQEREEREKEREREREERERKRRREEEER 279
Query: 336 RQNLQEEKERK 346
+ ++ER+
Sbjct: 280 EKERARDRERR 290
Score = 37.4 bits (85), Expect = 0.028
Identities = 18/74 (24%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 273 LVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAE 332
L E+ EREER + + ++++E R ++E+E+++ +RER++R +
Sbjct: 247 LKKEKQEREEREKER--EREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTS 304
Query: 333 ERRRQNLQEEKERK 346
+RR ++ K +
Sbjct: 305 DRRCSRSRDHKRSR 318
Score = 30.4 bits (67), Expect = 3.4
Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 277 RLEREERNQTQVL-RQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
R E EER + + R+++ + S + + +R+ R+ KR + E +++ + +RR
Sbjct: 273 RREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRE-RRRSRSRDRR 331
Query: 336 RQNLQEEKERK 346
R + ERK
Sbjct: 332 RSRSHDRSERK 342
Score = 29.3 bits (64), Expect = 7.5
Identities = 18/89 (20%), Positives = 39/89 (43%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
S+R R+ + +++ + R + +R +R+ R R R + + + + +
Sbjct: 304 SDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKH 363
Query: 335 RRQNLQEEKERKLECLPPEPSPDDPESVK 363
R ++ E++RK + S D SVK
Sbjct: 364 RSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 47.0 bits (110), Expect = 3e-05
Identities = 27/105 (25%), Positives = 56/105 (53%), Gaps = 4/105 (3%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERK----RRKEEEVQQQKLAE 332
RL++E+ Q +V +++QD L+ E+ER + EE RK R+++EE ++++ E
Sbjct: 412 RLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGE 471
Query: 333 ERRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERR 377
E+R+ + +++ + E L E + + +I K + + R
Sbjct: 472 EKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAR 516
Score = 42.7 bits (99), Expect = 7e-04
Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 264 FIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEE 323
F+ + L ER REER + R+QQ R EK+ ++R + ++R+ E
Sbjct: 48 FLKSDERQRLAKER--REEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQRE 105
Query: 324 EVQQQKLAEERRRQNLQEEKER 345
+ Q++ EE+R+Q L+EE+ER
Sbjct: 106 D-QKRAAVEEKRKQKLREEEER 126
Score = 38.9 bits (89), Expect = 0.010
Identities = 21/69 (30%), Positives = 45/69 (65%), Gaps = 5/69 (7%)
Query: 276 ERLEREERNQTQ---VLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAE 332
ER+E+EE+++ + + R+ ++E A +++E +KR+E E+K+++ EE ++K E
Sbjct: 421 ERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEE--KRKAGE 478
Query: 333 ERRRQNLQE 341
E +R+ +E
Sbjct: 479 EAKRKAEEE 487
Score = 38.9 bits (89), Expect = 0.010
Identities = 23/73 (31%), Positives = 44/73 (60%), Gaps = 6/73 (8%)
Query: 276 ERLEREE---RNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEE---EVQQQK 329
+RLEREE + + + LR +++ R QE+E+KK+E E+++ EE + +++
Sbjct: 429 DRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEEL 488
Query: 330 LAEERRRQNLQEE 342
L +E++ Q QE+
Sbjct: 489 LLKEKQEQEKQEK 501
Score = 34.7 bits (78), Expect = 0.18
Identities = 23/65 (35%), Positives = 42/65 (64%), Gaps = 6/65 (9%)
Query: 287 QVLRQQQDEAYLASLRADQEKERKK---REERERKRRKEEEVQQQKLAEERRRQNLQEEK 343
++L +++ +A L + +QE+ K+ R ERE +RK EE ++ +L EE R+Q +EE+
Sbjct: 402 KILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEE-ERLRLEEEARKQ--EEER 458
Query: 344 ERKLE 348
+R+ E
Sbjct: 459 KRQEE 463
Score = 31.2 bits (69), Expect = 2.0
Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 25/110 (22%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRR----KEEEVQQQKLA 331
ER +EE + Q +++ A +A++E K+++E+E++ + K++E + K
Sbjct: 457 ERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAR 516
Query: 332 E-------ERRRQNLQEEKER--------------KLECLPPEPSPDDPE 360
E ER + LQ E+ER + +PP+ +DP+
Sbjct: 517 EVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVPPQVKKEDPK 566
Score = 30.4 bits (67), Expect = 3.4
Identities = 23/64 (35%), Positives = 36/64 (56%), Gaps = 10/64 (15%)
Query: 290 RQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQ-----EEKE 344
R Q E +L S E++R +E RE +R K ++Q++ E+++R LQ EE+
Sbjct: 41 RPQGMEGFLKS----DERQRLAKERRE-EREKCLAAREQQILEKQKRARLQYEKQMEERW 95
Query: 345 RKLE 348
RKLE
Sbjct: 96 RKLE 99
Score = 29.6 bits (65), Expect = 5.8
Identities = 17/71 (23%), Positives = 42/71 (59%), Gaps = 3/71 (4%)
Query: 278 LEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQ 337
LE+++R + Q +Q ++ L +++E +KR E KR+++ ++++L E R+
Sbjct: 77 LEKQKRARLQYEKQMEER--WRKLEEQRQREDQKRAAVEEKRKQKLREEEERL-EAMMRR 133
Query: 338 NLQEEKERKLE 348
+L+ ++ +L+
Sbjct: 134 SLERTQQLELK 144
Score = 29.6 bits (65), Expect = 5.8
Identities = 14/52 (26%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 294 DEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKER 345
D A + A++ ++ + ++E+E + R E+E +Q +L E ++ +EE+ R
Sbjct: 396 DAGEAAKILAEKRRQARLQKEQEEQERVEKE-EQDRLEREELKRKAEEERLR 446
>gi|21264343 scaffold attachment factor B [Homo sapiens]
Length = 915
Score = 46.6 bits (109), Expect = 5e-05
Identities = 30/92 (32%), Positives = 50/92 (54%), Gaps = 12/92 (13%)
Query: 267 DANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERER--------- 317
D+ V ER ERE+R Q Q R++++ +A R +++R +RE ER
Sbjct: 616 DSESHSRVRERSEREQRMQAQWEREERERLEIARERLAFQRQRLERERMERERLERERMH 675
Query: 318 ---KRRKEEEVQQQKLAEERRRQNLQEEKERK 346
+RR+E+E ++ E RR+Q L+ E+ER+
Sbjct: 676 VEHERRREQERIHREREELRRQQELRYEQERR 707
Score = 33.5 bits (75), Expect = 0.40
Identities = 15/59 (25%), Positives = 35/59 (59%)
Query: 290 RQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLE 348
R+ +D + +R E+E++ + + ER+ R+ E+ +++LA +R+R + + +LE
Sbjct: 612 RKSRDSESHSRVRERSEREQRMQAQWEREERERLEIARERLAFQRQRLERERMERERLE 670
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 46.2 bits (108), Expect = 6e-05
Identities = 22/71 (30%), Positives = 47/71 (66%), Gaps = 9/71 (12%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
ER ER++R + QV ++++ +EKERK+R++RER R++ ++ +++K ER+
Sbjct: 159 ERKERKKRERKQVGEKEEER---------KEKERKERKKRERNRKERKKERERKERRERK 209
Query: 336 RQNLQEEKERK 346
++ ++E+ +K
Sbjct: 210 KERKKKEERKK 220
Score = 43.9 bits (102), Expect = 3e-04
Identities = 22/72 (30%), Positives = 43/72 (59%)
Query: 275 SERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER 334
SE ERE +T+ +++ E+ R ++EK +++RE+ ++ R ++E + ++ EER
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95
Query: 335 RRQNLQEEKERK 346
R+ + EKE K
Sbjct: 96 ERKKRRREKENK 107
Score = 43.9 bits (102), Expect = 3e-04
Identities = 24/73 (32%), Positives = 44/73 (60%), Gaps = 5/73 (6%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
ER +EER R+++ E ++E+ERK+R++RERK+ E+E ++++ + R
Sbjct: 132 ERERKEERK-----REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 336 RQNLQEEKERKLE 348
++ + KERK E
Sbjct: 187 KKRERNRKERKKE 199
Score = 43.9 bits (102), Expect = 3e-04
Identities = 21/75 (28%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLR--ADQEKERKKREERERKRRKEEEVQQQKLAEE 333
ER ERE + + + +++ E + ++E+ERK++E +ERK+R+ +++K E
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
Query: 334 RRRQNLQEEKERKLE 348
+ R+ ++E+++K E
Sbjct: 203 KERRERKKERKKKEE 217
Score = 42.7 bits (99), Expect = 7e-04
Identities = 27/74 (36%), Positives = 43/74 (58%), Gaps = 5/74 (6%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKRE---ERERKRRKEEEVQQQKLAE 332
++ E++ER +T ++++ +E+ERKK E ERERK RK+ E +Q E
Sbjct: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKE 175
Query: 333 ERRRQNLQEEKERK 346
E R++ +E KERK
Sbjct: 176 EERKE--KERKERK 187
Score = 42.4 bits (98), Expect = 9e-04
Identities = 23/70 (32%), Positives = 43/70 (61%), Gaps = 8/70 (11%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
ER ERE+R + + ++++ ++K +K+EERERK+R+ E ++ K EE+
Sbjct: 62 ERREREKRKREREKERKRERG------KKEKKGERKKEERERKKRRRE--KENKEGEEKE 113
Query: 336 RQNLQEEKER 345
++ +E+KER
Sbjct: 114 KRKKKEKKER 123
Score = 41.6 bits (96), Expect = 0.001
Identities = 21/70 (30%), Positives = 45/70 (64%), Gaps = 1/70 (1%)
Query: 277 RLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRR 336
R E+E + + ++++ E + + KER+++EER+R+ RKE E ++++ +ER R
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160
Query: 337 QNLQEEKERK 346
+ ++++ERK
Sbjct: 161 KE-RKKRERK 169
Score = 41.6 bits (96), Expect = 0.001
Identities = 21/68 (30%), Positives = 43/68 (63%), Gaps = 5/68 (7%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
ER+ER + + R+++ + R +++KERKK+EER+++R+K+ + ++ + +
Sbjct: 182 ERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWRE-----KERG 236
Query: 339 LQEEKERK 346
+E KERK
Sbjct: 237 KRERKERK 244
Score = 40.8 bits (94), Expect = 0.003
Identities = 20/77 (25%), Positives = 48/77 (62%), Gaps = 15/77 (19%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERER---------KRRKEEEVQQQK 329
++EER + + R+++++ +++++RKK+E++ER + RKEE ++++
Sbjct: 91 KKEERERKKRRREKENK------EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER 144
Query: 330 LAEERRRQNLQEEKERK 346
ER+++ ++E+ERK
Sbjct: 145 KERERKKEEREKERERK 161
Score = 40.0 bits (92), Expect = 0.004
Identities = 23/75 (30%), Positives = 44/75 (58%), Gaps = 4/75 (5%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEER- 334
E E EE+ + + +++ + + KE +KREER+ + RK+EE ++++ +ER
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK 164
Query: 335 ---RRQNLQEEKERK 346
R+Q ++E+ERK
Sbjct: 165 KRERKQVGEKEEERK 179
Score = 39.7 bits (91), Expect = 0.006
Identities = 19/64 (29%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Query: 285 QTQVLRQQQDEAYLASLRADQEKERKK--REERERKRRKEEEVQQQKLAEERRRQNLQEE 342
Q+++ ++++ + ++E ERKK RE +RKR +E+E ++++ +E++ + +EE
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 343 KERK 346
+ERK
Sbjct: 95 RERK 98
Score = 38.9 bits (89), Expect = 0.010
Identities = 17/73 (23%), Positives = 47/73 (64%), Gaps = 8/73 (10%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
E +REER + + ++++++ ++E++ +K+ ER++ KEEE ++++ E ++
Sbjct: 137 EERKREERKERERKKEEREK--------ERERKERKKRERKQVGEKEEERKEKERKERKK 188
Query: 336 RQNLQEEKERKLE 348
R+ ++E++++ E
Sbjct: 189 RERNRKERKKERE 201
Score = 36.2 bits (82), Expect = 0.062
Identities = 21/73 (28%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERK--RRKEEEVQQQKLAEE 333
ER ++ R + + ++ E + ++ + K+ +ERERK R++EE ++++ EE
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
Query: 334 RRRQNLQEEKERK 346
R ++ +E KERK
Sbjct: 154 REKE--RERKERK 164
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 46.2 bits (108), Expect = 6e-05
Identities = 21/70 (30%), Positives = 45/70 (64%), Gaps = 2/70 (2%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
ERE + + + +Q+D + D+EKER++++ER+R+R++E E +++ E +R +
Sbjct: 26 ERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERE--TERQRERQ 83
Query: 339 LQEEKERKLE 348
Q E++R+ +
Sbjct: 84 RQRERKRQTD 93
Score = 41.6 bits (96), Expect = 0.001
Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 6/73 (8%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQ---KLAEERR 335
+RE + +T R++ + D++ ER++ ERER+R++E E Q+Q K +R
Sbjct: 101 DRERKRETDRNRERNRKG---GRERDKQTERERDRERERQRQRERERQRQRERKRETDRE 157
Query: 336 RQNLQEEKERKLE 348
RQ E +ERK E
Sbjct: 158 RQRWAEREERKKE 170
Score = 40.0 bits (92), Expect = 0.004
Identities = 22/70 (31%), Positives = 37/70 (52%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
ERE Q + Q + E +E++R+ E+ER+R+KE + Q+Q+ E R
Sbjct: 18 ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETE 77
Query: 339 LQEEKERKLE 348
Q E++R+ E
Sbjct: 78 RQRERQRQRE 87
Score = 40.0 bits (92), Expect = 0.004
Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 7/79 (8%)
Query: 280 REERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNL 339
RE QT+ R ++ E +++ER+++ +RERKR + E Q+ EER+++
Sbjct: 120 RERDKQTERERDRERER-------QRQRERERQRQRERKRETDRERQRWAEREERKKERK 172
Query: 340 QEEKERKLECLPPEPSPDD 358
+E K+ + E E +D
Sbjct: 173 KERKKERKEKKKEEKRRED 191
Score = 40.0 bits (92), Expect = 0.004
Identities = 27/70 (38%), Positives = 45/70 (64%), Gaps = 9/70 (12%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKER-KKREERERKRRKEEEVQQ-QKLAEERRR 336
ERE + Q + RQ+Q E D+E++R +REER+++R+KE + ++ +K EE+RR
Sbjct: 133 ERERQRQRERERQRQRER---KRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRR 189
Query: 337 QNLQEEKERK 346
E+K+RK
Sbjct: 190 ----EDKKRK 195
Score = 39.3 bits (90), Expect = 0.007
Identities = 16/67 (23%), Positives = 39/67 (58%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
ERE R++ + +++D +++KER ++ +RER+ +E E Q+++ + R++
Sbjct: 32 ERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQ 91
Query: 339 LQEEKER 345
E+++
Sbjct: 92 TDRERDK 98
Score = 38.5 bits (88), Expect = 0.012
Identities = 19/73 (26%), Positives = 37/73 (50%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
ER + ER + + +D D+ +ER ++ RER ++ E E +++ + +R
Sbjct: 81 ERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQR 140
Query: 336 RQNLQEEKERKLE 348
+ Q ++ERK E
Sbjct: 141 ERERQRQRERKRE 153
Score = 38.5 bits (88), Expect = 0.012
Identities = 16/73 (21%), Positives = 42/73 (57%)
Query: 276 ERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERR 335
ER + R + + +++D + ++E++R++ +RE R ++ ++++ +ER+
Sbjct: 113 ERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERK 172
Query: 336 RQNLQEEKERKLE 348
++ +E KE+K E
Sbjct: 173 KERKKERKEKKKE 185
Score = 38.1 bits (87), Expect = 0.016
Identities = 18/68 (26%), Positives = 39/68 (57%), Gaps = 2/68 (2%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
+RE NQT+ R+ + D++ +R+K ER+++R ++ + +++ E R++
Sbjct: 24 QRERENQTE--RENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRE 81
Query: 339 LQEEKERK 346
Q ++ERK
Sbjct: 82 RQRQRERK 89
Score = 36.6 bits (83), Expect = 0.047
Identities = 15/70 (21%), Positives = 38/70 (54%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
+RE + +T ++ + E R +Q + + +R+R R ++ + ++K E ++ ++
Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
Query: 339 LQEEKERKLE 348
Q ++ER+ E
Sbjct: 64 RQRQRERETE 73
Score = 36.6 bits (83), Expect = 0.047
Identities = 17/66 (25%), Positives = 39/66 (59%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
E + +T+ R +Q E + R ++ ++R + ER+R+ +E+E ++QK + +R++
Sbjct: 10 ETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRE 69
Query: 339 LQEEKE 344
+ E+E
Sbjct: 70 RETERE 75
Score = 35.8 bits (81), Expect = 0.081
Identities = 17/67 (25%), Positives = 37/67 (55%), Gaps = 5/67 (7%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
E+E Q + RQ+Q E ++E ER++ +R+R+R+++ + ++ K + R++
Sbjct: 53 EKERERQKERDRQRQRER-----ETERETERQRERQRQRERKRQTDRERDKDRDRERKRE 107
Query: 339 LQEEKER 345
+ER
Sbjct: 108 TDRNRER 114
Score = 35.0 bits (79), Expect = 0.14
Identities = 18/70 (25%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
ERE +T+ R++Q + + ++ER K +RERKR + ++ + R +
Sbjct: 69 ERETERETERQRERQRQR---ERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQ 125
Query: 339 LQEEKERKLE 348
+ E++R+ E
Sbjct: 126 TERERDRERE 135
Score = 33.5 bits (75), Expect = 0.40
Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQN 338
ER+ + + R++Q E R ++E ER+ +RER+R++E + Q + ++ R +
Sbjct: 45 ERDRQTDREKERERQKERDRQRQR-ERETERETERQRERQRQRERKRQTDRERDKDRDRE 103
Query: 339 LQEEKERKLE 348
+ E +R E
Sbjct: 104 RKRETDRNRE 113
Score = 33.5 bits (75), Expect = 0.40
Identities = 20/85 (23%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Query: 270 QTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERE------RKRRKEE 323
QT ER ++ER++ + ++ + +++ERK++ +RE R+R++E
Sbjct: 49 QTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRET 108
Query: 324 EVQQQKLAEERRRQNLQEEKERKLE 348
+ +++ + R ++ Q E+ER E
Sbjct: 109 DRNRERNRKGGRERDKQTERERDRE 133
Score = 33.5 bits (75), Expect = 0.40
Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 5/73 (6%)
Query: 279 EREERNQTQVLRQQ-QDEAYLASLRADQEKERKKREER----ERKRRKEEEVQQQKLAEE 333
+RE + QT R + +D ++E+ RK ER ER+R +E E Q+Q+ E
Sbjct: 85 QRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERER 144
Query: 334 RRRQNLQEEKERK 346
+R++ + E +R+
Sbjct: 145 QRQRERKRETDRE 157
Score = 31.6 bits (70), Expect = 1.5
Identities = 16/54 (29%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAE 332
+RE + +T R++Q A + +++KERKK + ++K K E +++K E
Sbjct: 147 QRERKRETD--RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
Score = 30.8 bits (68), Expect = 2.6
Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 9/76 (11%)
Query: 279 EREERNQTQVLRQQQDEAYLASLRADQEKERKKREERE--------RKRRKEEEVQQQKL 330
E E + Q RQ+Q E + R +++K+R + +RE RK +E + Q ++
Sbjct: 71 ETERETERQRERQRQRERKRQTDR-ERDKDRDRERKRETDRNRERNRKGGRERDKQTERE 129
Query: 331 AEERRRQNLQEEKERK 346
+ R + Q E+ER+
Sbjct: 130 RDRERERQRQRERERQ 145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,363,836
Number of Sequences: 37866
Number of extensions: 917354
Number of successful extensions: 25558
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 596
Number of HSP's successfully gapped in prelim test: 605
Number of HSP's that attempted gapping in prelim test: 8463
Number of HSP's gapped (non-prelim): 9195
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.