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Search of human proteins with 247301318
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|247301318 non-protein coding RNA 153 isoform 2 [Homo
sapiens]
(570 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|247301318 non-protein coding RNA 153 isoform 2 [Homo sapiens] 1136 0.0
gi|118150654 non-protein coding RNA 153 isoform 1 [Homo sapiens] 1133 0.0
gi|247301334 non-protein coding RNA 153 isoform 3 [Homo sapiens] 1074 0.0
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 49 2e-05
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 45 1e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 44 3e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 43 7e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 43 7e-04
gi|54633319 PDZ domain-containing guanine nucleotide exchange fa... 43 9e-04
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 41 0.003
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 41 0.003
gi|148806891 hypothetical protein LOC54906 [Homo sapiens] 40 0.006
gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens] 39 0.010
gi|34996489 pleckstrin homology domain interacting protein [Homo... 39 0.017
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 39 0.017
gi|54633315 deoxynucleotidyltransferase, terminal, interacting p... 38 0.029
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 38 0.029
gi|190194423 SPARC-like 1 [Homo sapiens] 37 0.037
gi|190341024 SPARC-like 1 [Homo sapiens] 37 0.037
gi|210032580 SET domain containing 1B [Homo sapiens] 37 0.049
gi|17978469 cyclin T2 isoform b [Homo sapiens] 36 0.083
gi|154090979 hypothetical protein LOC57481 [Homo sapiens] 36 0.083
gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens] 36 0.11
gi|4502805 chromogranin A precursor [Homo sapiens] 36 0.11
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 36 0.11
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 36 0.11
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 36 0.11
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 35 0.14
gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens] 35 0.14
gi|38176300 nestin [Homo sapiens] 35 0.19
>gi|247301318 non-protein coding RNA 153 isoform 2 [Homo sapiens]
Length = 570
Score = 1136 bits (2938), Expect = 0.0
Identities = 570/570 (100%), Positives = 570/570 (100%)
Query: 1 MQLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQ 60
MQLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQ
Sbjct: 1 MQLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQ 60
Query: 61 MSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDN 120
MSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDN
Sbjct: 61 MSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDN 120
Query: 121 IDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLS 180
IDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLS
Sbjct: 121 IDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLS 180
Query: 181 PENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPW 240
PENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPW
Sbjct: 181 PENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPW 240
Query: 241 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 300
EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME
Sbjct: 241 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 300
Query: 301 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 360
GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA
Sbjct: 301 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 360
Query: 361 QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEA 420
QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEA
Sbjct: 361 QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEA 420
Query: 421 KPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRF 480
KPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRF
Sbjct: 421 KPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRF 480
Query: 481 QKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNAL 540
QKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNAL
Sbjct: 481 QKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNAL 540
Query: 541 WDESDDSNSEIEAALRPRNHNTDDSDDFYD 570
WDESDDSNSEIEAALRPRNHNTDDSDDFYD
Sbjct: 541 WDESDDSNSEIEAALRPRNHNTDDSDDFYD 570
>gi|118150654 non-protein coding RNA 153 isoform 1 [Homo sapiens]
Length = 673
Score = 1133 bits (2931), Expect = 0.0
Identities = 568/570 (99%), Positives = 570/570 (100%)
Query: 1 MQLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQ 60
++LEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQ
Sbjct: 104 LKLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQ 163
Query: 61 MSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDN 120
MSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDN
Sbjct: 164 MSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDN 223
Query: 121 IDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLS 180
IDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLS
Sbjct: 224 IDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLS 283
Query: 181 PENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPW 240
PENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPW
Sbjct: 284 PENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPW 343
Query: 241 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 300
EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME
Sbjct: 344 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 403
Query: 301 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 360
GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA
Sbjct: 404 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 463
Query: 361 QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEA 420
QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEA
Sbjct: 464 QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEA 523
Query: 421 KPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRF 480
KPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRF
Sbjct: 524 KPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRF 583
Query: 481 QKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNAL 540
QKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNAL
Sbjct: 584 QKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNAL 643
Query: 541 WDESDDSNSEIEAALRPRNHNTDDSDDFYD 570
WDESDDSNSEIEAALRPRNHNTDDSDDFYD
Sbjct: 644 WDESDDSNSEIEAALRPRNHNTDDSDDFYD 673
>gi|247301334 non-protein coding RNA 153 isoform 3 [Homo sapiens]
Length = 540
Score = 1074 bits (2777), Expect = 0.0
Identities = 538/539 (99%), Positives = 539/539 (100%)
Query: 32 KVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH 91
+VAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH
Sbjct: 2 QVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH 61
Query: 92 RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI 151
RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI
Sbjct: 62 RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI 121
Query: 152 GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK 211
GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK
Sbjct: 122 GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK 181
Query: 212 RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST 271
RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST
Sbjct: 182 RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST 241
Query: 272 SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL 331
SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL
Sbjct: 242 SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL 301
Query: 332 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 391
SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE
Sbjct: 302 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 361
Query: 392 CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA 451
CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA
Sbjct: 362 CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA 421
Query: 452 DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE 511
DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE
Sbjct: 422 DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE 481
Query: 512 ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD 570
ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD
Sbjct: 482 ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD 540
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 48.5 bits (114), Expect = 2e-05
Identities = 91/505 (18%), Positives = 178/505 (35%), Gaps = 39/505 (7%)
Query: 69 DFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQ 128
D S + S + S S ++ SSN +DS S+D+ + SD+ D K+
Sbjct: 570 DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS--DSSDSSDSKSDSS 627
Query: 129 IGEKMPVTASVLSEEEQTHCLEIGSNT-RHGKSNLSEGKKSAELNSPLRERLSPENRTTD 187
E + S+ ++ + N+ SN S S++ + S ++ +
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687
Query: 188 LKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHL 247
DSS S E S S S+ +S N S + S S
Sbjct: 688 DSSDSSDSSNS----------SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737
Query: 248 AHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEA 307
++ S + +S +S+ S S D + D ++
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 308 LKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVA 367
+ + + + + +S DS S ++ + + SD + G
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD---SSDGSDSD 854
Query: 368 TLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLN 427
+ D+S +++ + + + S S+ESS S S + NS ++ +
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSS--DSNESSNSSDSSDSSNSSDSDSS-----D 907
Query: 428 SVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASV 487
S + + SS D S+ N + + D++N +++ ++
Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSS--------------DNSNSSDSSNSSDSSDSSDSSNS 953
Query: 488 SHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESD-- 545
S S + S + ++ +N S S +SS+ S S + + S+ D SD
Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013
Query: 546 DSNSEIEAALRPRNHNTDDSDDFYD 570
DS++ +++ + N+ DS D D
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSD 1038
Score = 45.8 bits (107), Expect = 1e-04
Identities = 89/505 (17%), Positives = 176/505 (34%), Gaps = 18/505 (3%)
Query: 69 DFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQ 128
D S S + + D ++ SSN +DS S+D+ N SD+ + S
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834
Query: 129 IGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDL 188
+ S S + + S+ R SN S+ S++ ++ S ++ +
Sbjct: 835 SSNSSDSSDSSDSSDGS----DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890
Query: 189 KCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLA 248
DSS S + + + +S S+ ES N S SD
Sbjct: 891 SSDSSDSSN----SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD--- 943
Query: 249 HREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEAL 308
S S SSD + S S D + + + D ++
Sbjct: 944 --SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Query: 309 KLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVAT 368
+ + + + S + +SS ++ + + + DS ++
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 369 LKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSI-LNDNSGIKEAKPAVWLN 427
+ + + + +E + +SS+SS S S +D+S ++ + +
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS--SD 1119
Query: 428 SVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASV 487
S + + SS D S N + +E+ ++ +++ + + +D+S
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1179
Query: 488 SHLSGLNIGSGAFETKTANKIASEASFS--SSEGSPLSRHENKKKPVINLKSNALWDESD 545
S S + S + + +S++S S SS+ S S + + SN D SD
Sbjct: 1180 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239
Query: 546 DSNSEIEAALRPRNHNTDDSDDFYD 570
S+S + + ++D SD D
Sbjct: 1240 SSDSSDSSNSSDSSDSSDSSDSTSD 1264
Score = 44.3 bits (103), Expect = 3e-04
Identities = 83/500 (16%), Positives = 182/500 (36%), Gaps = 26/500 (5%)
Query: 71 STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQ----CLNKSDNIDGKAS 126
S++ S + N D + ++ SS+ +DS +S+D+ + SD+ + S
Sbjct: 642 SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701
Query: 127 LQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTT 186
+ +S S+ ++ + S+ S+ S S++ + S ++ +
Sbjct: 702 SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 761
Query: 187 DLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDH 246
DSS S+ + + +S S+ +S N S SD
Sbjct: 762 SNSSDSSDSSDSSDSS------DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815
Query: 247 LAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIE 306
S + + S SSD + S D + N + D
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875
Query: 307 ALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHV 366
+ + + ++ + + +S DS+ S+N+ + SD +
Sbjct: 876 SSDSSDSSDSNESSNSSDSS--DSSNSSDSDSSDSSNS-------SDSSDSSNSSDSSES 926
Query: 367 ATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWL 426
+ ++ NS + + + ++ + +SS+SS S S +++S ++
Sbjct: 927 SNSSDNSNS-SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS----- 980
Query: 427 NSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDAS 486
NS + + SS D S N + +++ ++ +++ + + +D+S
Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 487 VSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDD 546
S S + S + + +S++S SS+ S S + + + S+ D SD
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSS-DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099
Query: 547 SNSEIEAALRPRNHNTDDSD 566
S+S + + ++D SD
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSD 1119
Score = 41.2 bits (95), Expect = 0.003
Identities = 85/496 (17%), Positives = 174/496 (35%), Gaps = 22/496 (4%)
Query: 71 STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIG 130
S++ + + S S ++ S + +DS + +D+ N SD+ D S
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 131 EKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKC 190
+ S S + S+ S+ S+ S+E + S + ++D
Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720
Query: 191 DSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHR 250
+SS S+ + +S S+ +S + + S SD +
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD--SSD 778
Query: 251 EPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKL 310
S + S SSD + S D S N D ++
Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS--- 835
Query: 311 IHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLK 370
++ + + + + DS S ++ + + SD + + +
Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895
Query: 371 EHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVP 430
+ NS +++ + + + S SSESS S +DNS ++ NS
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSS--DSSESSNS-----SDNSNSSDSS-----NSSD 943
Query: 431 TREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHL 490
+ + SS D S + + +++ + + D+++ +++ +D+S S
Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS----SDSSDSSD 999
Query: 491 SGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSE 550
S N + + +++ S S +SS+ S S + + S+ D SD SNS
Sbjct: 1000 SS-NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 551 IEAALRPRNHNTDDSD 566
+ + ++D SD
Sbjct: 1059 DSSDSSDSSDSSDSSD 1074
Score = 38.9 bits (89), Expect = 0.013
Identities = 88/504 (17%), Positives = 179/504 (35%), Gaps = 17/504 (3%)
Query: 71 STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIG 130
S++ + + N S S + SSN +DS S+D+ N SD+ D S
Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS--NSSDSSDSSDSSDGS 851
Query: 131 EKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLK- 189
+ S S + SN+ S+ S+ +S+ + S ++ ++D
Sbjct: 852 DSDSSNRSDSSNSSDSSDSSDSSNSSDS-SDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910
Query: 190 -CDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLA 248
DSS S + + +S + S+ +S N S SD
Sbjct: 911 SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970
Query: 249 HREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEAL 308
S + S SSD + S + D S + + + +
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD----SSDSSDSSDSSNSSDSSNSSD 1026
Query: 309 KLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVAT 368
++ + S++ + + S DS S ++ + + SD + +
Sbjct: 1027 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1086
Query: 369 LKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNS 428
+ NS ++ + S+ S S+ S S +D+S ++ + +S
Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS--DS 1144
Query: 429 VPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVS 488
+ E SS D S + + +++ ++ +++ + + +D+S S
Sbjct: 1145 SDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204
Query: 489 HLSGLNIGSGAFETKTANKIASEASFS-----SSEGSPLSRHENKKKPVINL-KSNALWD 542
S + S + + +S++S S SS+ S S N + S++ D
Sbjct: 1205 SDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSD 1264
Query: 543 ESDDSNSEIEAALRPRNHNTDDSD 566
+D+S+S+ ++ N + DSD
Sbjct: 1265 SNDESDSQSKSGNGNNNGSDSDSD 1288
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 45.4 bits (106), Expect = 1e-04
Identities = 80/370 (21%), Positives = 143/370 (38%), Gaps = 38/370 (10%)
Query: 197 EGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQK 256
EG++ RE E+EE + + + E E E K HS E
Sbjct: 309 EGKVAQREE-ELEE--TGNQHNDVEIEEAGEEEEKEIAIVHSDAE--------------- 350
Query: 257 PFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPN-PGGKMEGEDGIEALKLIHAEQ 315
K QEEEE+ ++ + + E+ + ES + Q + P M+ + +E +K + A+Q
Sbjct: 351 ---KEQEEEEQK----QEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQ 403
Query: 316 ERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVG-QHVATLK-EHD 373
E + + ++ P + S P E PD + G ++V+ L E +
Sbjct: 404 EVMETNRVESV------EPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKE 457
Query: 374 NSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTRE 433
+ KEE + + + +S S S P + + E L P
Sbjct: 458 SEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVT 517
Query: 434 QEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGL 493
QE G +K+ + +TE +L ++ ++T+ R + + + S
Sbjct: 518 QE--QGHLLPERKDFPVESVKLTEVPVEPVL--TVHPESKSKTKTRSRSRGRARNKTSKS 573
Query: 494 NIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEA 553
S + + +++ +S + SSS GS SR + + S+ S S+SE +
Sbjct: 574 RSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRS 633
Query: 554 ALRPRNHNTD 563
R R HN D
Sbjct: 634 RSRGRGHNRD 643
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 44.3 bits (103), Expect = 3e-04
Identities = 65/289 (22%), Positives = 117/289 (40%), Gaps = 44/289 (15%)
Query: 122 DGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERL-- 179
+ K+ ++ K P A +EE E+ S + E K E SP +E
Sbjct: 515 EAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKS 574
Query: 180 -----SPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQ 234
SPE + K ++ S +E + + V+E+ SP + PV E E K
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE----EAKSPA 630
Query: 235 EKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPN 294
E SP + S + +++ P + E+EE+ +SPE +
Sbjct: 631 EVKSPEKAKSP----TKEEAKSPEKAKSPEKEEA------------------KSPEKAKS 668
Query: 295 PGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPD 354
P K E + +A + AE + + K+ + + SP+ K +P +E ++P+
Sbjct: 669 P-VKAEAKSPEKAKSPVKAEAK--SPEKAKSPVKEEAKSPEKAK-----SPVKEEAKSPE 720
Query: 355 SDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSES 403
++ V + T ++ + VKEEA + KA + E + + S E+
Sbjct: 721 K--AKSPVKEEAKTPEKAKSPVKEEAKS-PEKAKSPEKAKTLDVKSPEA 766
Score = 43.9 bits (102), Expect = 4e-04
Identities = 59/274 (21%), Positives = 110/274 (40%), Gaps = 29/274 (10%)
Query: 131 EKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRT-TDLK 189
E+ VT V EEE+ E G G+ +EG + + P E SPE + +K
Sbjct: 462 EETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVK 521
Query: 190 CDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYC----ESENKWSQEKHSPWEGVSD 245
++ S +E + +E + + SP + P E E+++ +E SP E S
Sbjct: 522 EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSP 581
Query: 246 HLAH----------REPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNP 295
A E KS + + +EE +S + + ++ ++SPE +P
Sbjct: 582 EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP 641
Query: 296 GGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKE---------SSTNAPT 346
K E + +A ++E + K+ + SP+ K +P
Sbjct: 642 -TKEEAKSPEKAKS--PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698
Query: 347 REPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEA 380
+E ++P+ ++ V + + ++ + VKEEA
Sbjct: 699 KEEAKSPEK--AKSPVKEEAKSPEKAKSPVKEEA 730
Score = 42.0 bits (97), Expect = 0.002
Identities = 60/286 (20%), Positives = 110/286 (38%), Gaps = 27/286 (9%)
Query: 132 KMPVTASVLSEEE-QTHCLEIGSNTRHGKSNLSEGKKSAE-LNSPLRERL-------SPE 182
K PV S E+ ++ E + KS + E K+ E SP++E SPE
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754
Query: 183 N-RTTDLKC--------DSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWS 233
+T D+K + + + + V+E+ SP + P+ E ++ K
Sbjct: 755 KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEI 814
Query: 234 QEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEP-- 291
+K V + +E K ++P +K +EE+ + + + S E+ E+P+P
Sbjct: 815 PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 874
Query: 292 --QPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREP 349
+ P + E +EA K AE ++ + EK + D++ + T +EP
Sbjct: 875 EEKKEPAVEKPKESKVEA-KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP 933
Query: 350 ----GQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 391
+ P + + KE EE KA ++
Sbjct: 934 DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979
Score = 33.1 bits (74), Expect = 0.70
Identities = 40/199 (20%), Positives = 76/199 (38%), Gaps = 6/199 (3%)
Query: 243 VSDHLAHREPKSQKPFRKMQEE----EEESWSTSSDLTISISEDDLILESPEPQPNPGGK 298
VS H+ + + K K ++E EE++ T ++ E+ E + G +
Sbjct: 432 VSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEE 491
Query: 299 MEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVP 358
E E G E K AE+ K+ + + SP +E +S + P + +
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP-AEAKSPEKEEAKSPAEVKSPEKA 550
Query: 359 RAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIK 418
++ + + E + KEEA + + + E + A ++S S S +K
Sbjct: 551 KSPAKEEAKSPPEAKSPEKEEAKS-PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Query: 419 EAKPAVWLNSVPTREQEVS 437
E + P +E+ S
Sbjct: 610 EEAKSPAEAKSPVKEEAKS 628
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 43.1 bits (100), Expect = 7e-04
Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 23/278 (8%)
Query: 227 ESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLIL 286
E+E + K SP + + + E + ++ + +EEEE+ + S SE +
Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 559
Query: 287 ESPEPQPNPG---GKMEGEDGIEALKLIHAEQERVALSTEKNCILQT-LSSPDSEKESST 342
E E + G + EGE+ EA + E++ ++T++ + + P+ K
Sbjct: 560 EKEEGEQEEGETEAEAEGEEA-EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 618
Query: 343 NAPTREPGQTPDSDVPRAQVGQH---VATLKEHDNS------VKEEATALLRKALTEECG 393
+P E G++P P + G+ + ++E S V+E+ + + K+ EE
Sbjct: 619 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 678
Query: 394 R----RSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKS----- 444
+ +S + ++S + KE K A V +E++ K
Sbjct: 679 KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 738
Query: 445 KKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQK 482
K+E VA + IT++ L K+ + Q E +K
Sbjct: 739 KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEK 776
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 43.1 bits (100), Expect = 7e-04
Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 23/278 (8%)
Query: 227 ESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLIL 286
E+E + K SP + + + E + ++ + +EEEE+ + S SE +
Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 183
Query: 287 ESPEPQPNPG---GKMEGEDGIEALKLIHAEQERVALSTEKNCILQT-LSSPDSEKESST 342
E E + G + EGE+ EA + E++ ++T++ + + P+ K
Sbjct: 184 EKEEGEQEEGETEAEAEGEEA-EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 242
Query: 343 NAPTREPGQTPDSDVPRAQVGQH---VATLKEHDNS------VKEEATALLRKALTEECG 393
+P E G++P P + G+ + ++E S V+E+ + + K+ EE
Sbjct: 243 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 302
Query: 394 R----RSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKS----- 444
+ +S + ++S + KE K A V +E++ K
Sbjct: 303 KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 362
Query: 445 KKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQK 482
K+E VA + IT++ L K+ + Q E +K
Sbjct: 363 KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEK 400
>gi|54633319 PDZ domain-containing guanine nucleotide exchange factor
I [Homo sapiens]
Length = 1601
Score = 42.7 bits (99), Expect = 9e-04
Identities = 75/342 (21%), Positives = 132/342 (38%), Gaps = 49/342 (14%)
Query: 71 STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQ-- 128
S+ H SP + S ++ +A+S N++DS + S+ + ++ A+LQ
Sbjct: 1232 SSLHSSPPASPQGSPHKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQDE 1291
Query: 129 --IGEKMPVTASVLSEEEQTHCLEIGSNTRHGKS----NLSEGKKSAELNSPLRERLSPE 182
+ + V S + E+ H IG +++HG S K A +S E +S E
Sbjct: 1292 RCSSQALAVPESTGALEKTEHASGIGDHSQHGPGWTLLKPSLIKCLAVSSSVSNEEISQE 1351
Query: 183 NRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEG 242
+ + DS GS + H + P P S W
Sbjct: 1352 HIIIEA-ADSGRGSWTSCSSSSHDNFQSL-------PNPKS--------WDFLNSYRHTH 1395
Query: 243 VSDHLAHREPKSQKPFRKMQE-----------EEEESWSTSSDLTISISEDDLILESPEP 291
+ D +A EP +P+ + E +SW++SS L+ + + ++
Sbjct: 1396 LDDPIAEVEPTDSEPYSCSKSCSRTCGQCKGSLERKSWTSSSSLSDTYEPNYGTVKRRVL 1455
Query: 292 QPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQ 351
+ P EG D +A ++ + V STEK I+ ++SP + REP
Sbjct: 1456 ESTPAESSEGLDPKDATDPVY---KTVTSSTEKGLIVYCVTSPKKDDR------YREPPP 1506
Query: 352 TPDS----DVPRAQVGQHVATLKEHDNSVKEEATALLRKALT 389
TP + + G H LK D SV + + ++ +L+
Sbjct: 1507 TPPGYLGISLADLKEGPH-THLKPPDYSVAVQRSKMMHNSLS 1547
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 41.2 bits (95), Expect = 0.003
Identities = 56/225 (24%), Positives = 84/225 (37%), Gaps = 34/225 (15%)
Query: 241 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 300
E S PKS+K +K QE + + + D+ + SE D S + + G E
Sbjct: 155 ERASARSKRSSPKSRKGKKKSQENKNKG-NKIQDIQLKTSEPDFT--SANMRDSAEGPKE 211
Query: 301 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 360
E+ A L E+ LQ ++S + E +T AP EP PD + A
Sbjct: 212 DEEKPSASAL------------EQPATLQEVASQEVPPELATPAPAWEPQPEPDERLEAA 259
Query: 361 -----QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNS 415
+G+ +E D +E+ E+ G A +E+S P I D
Sbjct: 260 ACEVNDLGEEEEEEEEEDEEEEEDDD----DDELEDEGEEEASMPNENSVKEPEIRCDE- 314
Query: 416 GIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEA 460
KP L T +E C + + A IP T+ EA
Sbjct: 315 -----KPEDLLEEPKTTSEETLEDCSEVTP----AMQIPRTKEEA 350
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 41.2 bits (95), Expect = 0.003
Identities = 56/225 (24%), Positives = 84/225 (37%), Gaps = 34/225 (15%)
Query: 241 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 300
E S PKS+K +K QE + + + D+ + SE D S + + G E
Sbjct: 155 ERASARSKRSSPKSRKGKKKSQENKNKG-NKIQDIQLKTSEPDFT--SANMRDSAEGPKE 211
Query: 301 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 360
E+ A L E+ LQ ++S + E +T AP EP PD + A
Sbjct: 212 DEEKPSASAL------------EQPATLQEVASQEVPPELATPAPAWEPQPEPDERLEAA 259
Query: 361 -----QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNS 415
+G+ +E D +E+ E+ G A +E+S P I D
Sbjct: 260 ACEVNDLGEEEEEEEEEDEEEEEDDD----DDELEDEGEEEASMPNENSVKEPEIRCDE- 314
Query: 416 GIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEA 460
KP L T +E C + + A IP T+ EA
Sbjct: 315 -----KPEDLLEEPKTTSEETLEDCSEVTP----AMQIPRTKEEA 350
>gi|148806891 hypothetical protein LOC54906 [Homo sapiens]
Length = 2430
Score = 40.0 bits (92), Expect = 0.006
Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)
Query: 179 LSPENRTT---DLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSE----YCESE-- 229
+ PEN T DL +S + + L + + S S PVSE +C SE
Sbjct: 509 VQPENTTAAHNDLPENSIVNYDSQALNM----LADLALSSATSSTPVSEARNLHCSSELP 564
Query: 230 -NKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILES 288
N K + G SDH HR K+QK + ++ SDLT+S E+ L+ S
Sbjct: 565 QNDVLLSKENSLRGTSDHEYHRGVKTQKGELLPNPSSDRKSNSGSDLTVSQDEESLVPCS 624
Query: 289 PEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAP--T 346
P E E L+ A Q +L T S +E +P
Sbjct: 625 QAPAKAQSALTE-----EMLESSDASQSSSVSVEHSYALLLTEHSKKHLQEREILSPLFP 679
Query: 347 REPGQTPDSDVPRAQV 362
R ++P++ P +V
Sbjct: 680 RNGTKSPEAATPVGKV 695
>gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]
Length = 880
Score = 39.3 bits (90), Expect = 0.010
Identities = 55/270 (20%), Positives = 102/270 (37%), Gaps = 38/270 (14%)
Query: 332 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRK----- 386
SS S + ST++PT P TP P ++ Q V H + + ++++ K
Sbjct: 414 SSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSM 473
Query: 387 ALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLN------SVPTREQEVSSGC 440
+L E+ + S + P + S + LN S+ + + + S C
Sbjct: 474 SLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHC 533
Query: 441 GDKSKKENVAADIPITETEAYQLLK--KATLQDNT---------NQTENRFQKT------ 483
+ ++E+ + E K + + +D T N EN T
Sbjct: 534 KSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFT 593
Query: 484 ----DASVSHLSGLNI--GSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKS 537
D++ + LN+ G E +++ A E S + + +EN P ++
Sbjct: 594 AKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQT 653
Query: 538 NALWDESDDSNSEIEAALRPRNHNTDDSDD 567
A + + S ++AL+ +TDDSDD
Sbjct: 654 EATGPSAHEETSTRDSALQ----DTDDSDD 679
>gi|34996489 pleckstrin homology domain interacting protein [Homo
sapiens]
Length = 1821
Score = 38.5 bits (88), Expect = 0.017
Identities = 68/291 (23%), Positives = 124/291 (42%), Gaps = 48/291 (16%)
Query: 73 EHKSPQPTKNFSIPDPHSH---------RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDG 123
E+K P +KN + H H +QT Q + T S + +T ++ + +G
Sbjct: 765 ENKIPTVSKNHA----HEHFLDLGESKKQQTNQHNYRTRSALEETPRPSEEIE-----NG 815
Query: 124 KASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPEN 183
+S GE + V+ SEEE+ GS++ + S+ S+ A +N +++ P+N
Sbjct: 816 SSSSDEGEVVAVSGGT-SEEEERAWHSDGSSSDYS-SDYSDWTADAGINLQPPKKV-PKN 872
Query: 184 RTTDLKCDSSSGSEGEILTREHIEVEEKRASP----PVSP------------IPVSEYCE 227
+T + S E E ++ I+ E+K+ + P+SP + V E
Sbjct: 873 KTKKAESSSDEEEESEKQKQKQIKKEKKKVNEEKDGPISPKKKKPKERKQKRLAVGEL-- 930
Query: 228 SENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILE 287
+EN + E+ P ++D + R PF +E + + + ++ + I
Sbjct: 931 TENGLTLEEWLPSTWITDTIPRR-----CPFVPQMGDEVYYFRQGHEAYVEMARKNKIY- 984
Query: 288 SPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEK 338
S P+ P KME + E +K++ + E V L T C+ PD+ K
Sbjct: 985 SINPKKQPWHKMELREQ-ELMKIVGIKYE-VGLPT-LCCLKLAFLDPDTGK 1032
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 38.5 bits (88), Expect = 0.017
Identities = 103/519 (19%), Positives = 192/519 (36%), Gaps = 59/519 (11%)
Query: 67 MRDFSTEHKSPQPTKNF-SIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGK- 124
M D + ++ P++ F +I S + + S D V N +K+D DGK
Sbjct: 1143 MSDETNNEETESPSQEFVNITKYESSLYSQEYSKPAD---VTPLNGFSEGSKTDATDGKD 1199
Query: 125 -----ASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERL 179
+++ M S +C E+ ++T + S +++ L
Sbjct: 1200 YNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSL 1259
Query: 180 SPENRTTDLKCDSSSGSEGEILTREHIEV----EEKRASPPVSPIPVSEYCESENKWSQE 235
SP + K S LT I+V E SP V+ V E+C S + E
Sbjct: 1260 SPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPEDKTLE 1319
Query: 236 KHSPWEGVSDHLAH----REPKSQKPFRKMQE--EEEESWSTSSDLTISISEDDLILESP 289
SP + V+ H + P +K E E+ + S + + + E++ SP
Sbjct: 1320 VVSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKPPAVPVSFEFSDAKDENERASVSP 1379
Query: 290 EPQPNPGGKMEGEDGIEALK---LIHAEQERVA-LSTEKNCILQTLSSPDSEKESSTNAP 345
+P P + E + L+ LI +E + LS + + SP EK +P
Sbjct: 1380 MDEPVPDSESPIEKVLSPLRSPPLIGSESAYESFLSADDKASGRGAESPFEEKSGKQGSP 1439
Query: 346 TREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSC 405
+ +P S++ + Q K+E + + E+ G+ E+
Sbjct: 1440 DQ---VSPVSEMTSTSLYQD-----------KQEGKSTDFAPIKEDFGQEKKTDDVEAMS 1485
Query: 406 SLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLK 465
S P++ D + + P D S+ + D ++ +E K
Sbjct: 1486 SQPALALDERKLGDVSPTQI----------------DVSQFGSFKEDTKMSISEGTVSDK 1529
Query: 466 KATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRH 525
AT D E+ + + V+ +S ++ + +F T + ++ S + GSP S
Sbjct: 1530 SATPVDE-GVAEDTYSHME-GVASVSTASVATSSFPEPTTDDVS--PSLHAEVGSPHSTE 1585
Query: 526 ENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDD 564
+ V +++ + E++ S S+ E RP + + D
Sbjct: 1586 VDDSLSVSVVQTPTTFQETEMSPSK-EECPRPMSISPPD 1623
>gi|54633315 deoxynucleotidyltransferase, terminal, interacting
protein 2 [Homo sapiens]
Length = 756
Score = 37.7 bits (86), Expect = 0.029
Identities = 70/309 (22%), Positives = 110/309 (35%), Gaps = 60/309 (19%)
Query: 4 EYETQIKKMLCSKDS----LGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGR 59
E +Q+K + +D+ L + T +++ V+VH +NS M AT+ +GR
Sbjct: 315 EKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVGR 374
Query: 60 QMSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSD 119
++ KSP D S + +S V+ S D +N
Sbjct: 375 ----------WNNNKKSP-----IKASDLTKFGDCGGSDDEEESTVISVSED---MNSEG 416
Query: 120 NIDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAEL---NSPLR 176
N+D + ++ P T S+ + L + S+ +S SE ++ NS R
Sbjct: 417 NVDFECDTKLYTSAPNT----SQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQR 472
Query: 177 ERLSPENRTTDLKCDSS----SGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKW 232
E LS + T L CD++ + G + EE +A SE E K
Sbjct: 473 ESLSGD--TGSLSCDNALFVIDTTPGMSADKNFYLEEEDKA---------SEVAIEEEKE 521
Query: 233 SQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQ 292
+E E SDH +E E+ +S D S L L S
Sbjct: 522 EEEDEKSEEDSSDH----------------DENEDEFSDEEDFLNSTKAKLLKLTSSSID 565
Query: 293 PNPGGKMEG 301
P K G
Sbjct: 566 PGLSIKQLG 574
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 37.7 bits (86), Expect = 0.029
Identities = 87/416 (20%), Positives = 152/416 (36%), Gaps = 63/416 (15%)
Query: 123 GKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPE 182
G++ L+ EK + V EEE + +R K +L+ KK +P + PE
Sbjct: 38 GRSHLEPEEKQALKRLV--EEELLKMQVDEAASREDKLDLT--KKGKRPPTPCSD---PE 90
Query: 183 NRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEG 242
+ +S SGSE PP +E ++ + + E
Sbjct: 91 RKRFRFNSESESGSEAS---------SPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEE 141
Query: 243 VSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTI---------SISEDDLILESPEPQP 293
SD R+ +Q+ +EEE+ + + S+S ES E +
Sbjct: 142 SSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAREESEESEA 201
Query: 294 NP----GGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREP 349
P K+EG G ++LK E E L+ +K ++E +E
Sbjct: 202 EPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKK-----------EQREEEVEEEEKEE 250
Query: 350 GQTPDSDVPRAQV-GQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSL- 407
+ PR + G+ + +E K +A LL + +EE + +A +S
Sbjct: 251 DEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDRE 310
Query: 408 PSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKA 467
P + + + K L+ + E E SG G+ + K + +K
Sbjct: 311 PPVQRKSEDRTQLKGGKRLSG--SSEDEEDSGKGEPTAKGS----------------RKM 352
Query: 468 TLQDNTNQTENRFQKTDASVSHLSGLNIG--SGAFETKTANKIASEASFSSSEGSP 521
+T+ E+ ++ + S S G G K++ K + +S SSS+GSP
Sbjct: 353 ARLGSTSGEESDLER-EVSDSEAGGGPQGERKNRSSKKSSRKGRTRSSSSSSDGSP 407
>gi|190194423 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 37.4 bits (85), Expect = 0.037
Identities = 62/319 (19%), Positives = 121/319 (37%), Gaps = 39/319 (12%)
Query: 262 QEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALS 321
+E E+E+ ++ D + +E +L+S E + +G+ + L L E LS
Sbjct: 50 EENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAE-QGKSSSQELGLKDQEDSDGHLS 108
Query: 322 -------TEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDN 374
TE ++ S EK+ S N PG + +D + + + +E+
Sbjct: 109 VNLEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTD---SNQQESITKREENQE 165
Query: 375 SVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILN-DNSGIKEAKPAVWLNSVPTRE 433
+ + L ++ G R + + P+I N + KE N R+
Sbjct: 166 QPRNYSHHQLNRSSKHSQGLRDQGNQEQD----PNISNGEEEEEKEPGEVGTHNDNQERK 221
Query: 434 QEVS-SGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSG 492
E+ K +++N +D + E++ + K + + + ++A + +
Sbjct: 222 TELPREHANSKQEEDNTQSDDILEESDQPTQVSKMQEDEFDQGNQEQEDNSNAEMEEENA 281
Query: 493 LNIGSGAFETKTANKIASEASFSSSEGSP----LSRHENKKKPVINLKSNALWDESDDSN 548
N+ NK E + S EG +S H+ ++ ++ L + +DD N
Sbjct: 282 SNV----------NKHIQETEWQSQEGKTGLEAISNHKETEEKTVS--EALLMEPTDDGN 329
Query: 549 SEIEAALRPRNHNTDDSDD 567
+ PRNH DD D
Sbjct: 330 TT------PRNHGVDDDGD 342
>gi|190341024 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 37.4 bits (85), Expect = 0.037
Identities = 62/319 (19%), Positives = 121/319 (37%), Gaps = 39/319 (12%)
Query: 262 QEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALS 321
+E E+E+ ++ D + +E +L+S E + +G+ + L L E LS
Sbjct: 50 EENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAE-QGKSSSQELGLKDQEDSDGHLS 108
Query: 322 -------TEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDN 374
TE ++ S EK+ S N PG + +D + + + +E+
Sbjct: 109 VNLEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTD---SNQQESITKREENQE 165
Query: 375 SVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILN-DNSGIKEAKPAVWLNSVPTRE 433
+ + L ++ G R + + P+I N + KE N R+
Sbjct: 166 QPRNYSHHQLNRSSKHSQGLRDQGNQEQD----PNISNGEEEEEKEPGEVGTHNDNQERK 221
Query: 434 QEVS-SGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSG 492
E+ K +++N +D + E++ + K + + + ++A + +
Sbjct: 222 TELPREHANSKQEEDNTQSDDILEESDQPTQVSKMQEDEFDQGNQEQEDNSNAEMEEENA 281
Query: 493 LNIGSGAFETKTANKIASEASFSSSEGSP----LSRHENKKKPVINLKSNALWDESDDSN 548
N+ NK E + S EG +S H+ ++ ++ L + +DD N
Sbjct: 282 SNV----------NKHIQETEWQSQEGKTGLEAISNHKETEEKTVS--EALLMEPTDDGN 329
Query: 549 SEIEAALRPRNHNTDDSDD 567
+ PRNH DD D
Sbjct: 330 TT------PRNHGVDDDGD 342
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 37.0 bits (84), Expect = 0.049
Identities = 52/239 (21%), Positives = 91/239 (38%), Gaps = 15/239 (6%)
Query: 159 KSNLSEGKKSAELNSPLRERLSPENRTTDLKCD--SSSGSEGEILTREHIEVEEKRASPP 216
K +LSE ++S E E E+ D D S + + E E +E +
Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEE 1097
Query: 217 VSPIPVSEYCESENKWSQEKHSPWEGVSDHL-AHREPKSQKPFRKMQEEEEESWSTSSDL 275
+ V+ E+ + + S +E S+ + E + + R+ +EEEEE + +
Sbjct: 1098 ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEES 1157
Query: 276 TISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPD 335
S +D + E PG G+E + + E E VA + + +
Sbjct: 1158 MASAGPEDFEQDGEEAALAPGAPAVDSLGME--EEVDIETEAVAPEERPSMLDEPPLPVG 1215
Query: 336 SEKESSTNAPTREPGQTPD-----SDVPRAQVGQHVATLK-----EHDNSVKEEATALL 384
E+ + + P EPG + + S P A+ + L EHD V+ E +L
Sbjct: 1216 VEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMML 1274
>gi|17978469 cyclin T2 isoform b [Homo sapiens]
Length = 730
Score = 36.2 bits (82), Expect = 0.083
Identities = 49/213 (23%), Positives = 78/213 (36%), Gaps = 22/213 (10%)
Query: 93 QTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEIG 152
Q A SS+VT ++ +D + SL++ +P T S+EE +++
Sbjct: 471 QAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVS 530
Query: 153 SNTRHGKSNLSEGKK-------SAELNSPLRERLSPENRTTDLK---CDSSSGSEGEILT 202
S+ RH S+ GK S + +E S + T+ K S S S G +
Sbjct: 531 SSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHS 590
Query: 203 REHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQ 262
+ I R SP+ +S S + S K H+ K
Sbjct: 591 ADGIPPTVLR-----SPVGLSSDGISSSSSSSRKRL-------HVNDASHNHHSKMSKSS 638
Query: 263 EEEEESWSTSSDLTISISEDDLILESPEPQPNP 295
+ S S+SS + IS + + P P P P
Sbjct: 639 KSSGSSSSSSSSVKQYISSHNSVFNHPLPPPPP 671
>gi|154090979 hypothetical protein LOC57481 [Homo sapiens]
Length = 1709
Score = 36.2 bits (82), Expect = 0.083
Identities = 60/264 (22%), Positives = 97/264 (36%), Gaps = 34/264 (12%)
Query: 215 PPVSPIPVSEYCESENKWSQEKHSPWEGV-SDHLAH-REPKSQKPFRKMQEEEEESWSTS 272
PP S S ++E S ++ P EG S+ LAH +S F QE ES S
Sbjct: 763 PPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFV 822
Query: 273 SDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLS 332
DL+ S E DL S +AL+ E E + TE + ++ +
Sbjct: 823 EDLSSSEEELDLRCLS-----------------QALE----EPEDAEVFTESSSYVEKYN 861
Query: 333 SPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEEC 392
+ D S + P R P Q + +V E N ++ L +
Sbjct: 862 TSDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQ----LPSRCPSQP 917
Query: 393 GRRSAIHSSESSCSLPSILNDNSGIKEAKP----AVWLNSVPTREQEVSSGCGDKSKKEN 448
+ + S+ + + + ++ P W+N P EQEVSS + +E+
Sbjct: 918 IMNPTVQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVN--PKVEQEVSSSPKSMAVEES 975
Query: 449 VAADIPITETEAYQLLKKATLQDN 472
++ P+ Q L +Q N
Sbjct: 976 ISMK-PLPPKLLCQPLMNPKVQQN 998
>gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]
Length = 860
Score = 35.8 bits (81), Expect = 0.11
Identities = 55/259 (21%), Positives = 98/259 (37%), Gaps = 36/259 (13%)
Query: 332 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 391
SS S + ST++PT P TP P ++ Q V H + + + L+ +
Sbjct: 414 SSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDNN----NEKLSPK 469
Query: 392 CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA 451
G + S S + S IK W +S+ + + + S C + ++E+
Sbjct: 470 PGTGEPVLSLHYSTEGTT----TSTIKLNFTDEW-SSIASSSRGIGSHCKSEGQEESFVP 524
Query: 452 DIPITETEAYQLLK--KATLQDNT---------NQTENRFQKT----------DASVSHL 490
+ E K + + +D T N EN T D++
Sbjct: 525 QSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGER 584
Query: 491 SGLNI--GSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSN 548
+ LN+ G E +++ A E S + + +EN P ++ A + +
Sbjct: 585 NDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEET 644
Query: 549 SEIEAALRPRNHNTDDSDD 567
S ++AL+ +TDDSDD
Sbjct: 645 STRDSALQ----DTDDSDD 659
>gi|4502805 chromogranin A precursor [Homo sapiens]
Length = 457
Score = 35.8 bits (81), Expect = 0.11
Identities = 38/154 (24%), Positives = 66/154 (42%), Gaps = 15/154 (9%)
Query: 159 KSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVS 218
+ + E +KS E R + PE + K + ++ + GE E E EE + P +
Sbjct: 133 REDSKEAEKSGEATDGARPQALPEPMQ-ESKAEGNNQAPGE----EEEEEEEATNTHPPA 187
Query: 219 PIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPK-SQKP---FRKMQEEEEESWSTSSD 274
+P +Y + + E G+S L RE S +P ++ +EEEEE + + +
Sbjct: 188 SLPSQKYPGPQAEGDSE------GLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGE 241
Query: 275 LTISISEDDLILESPEPQPNPGGKMEGEDGIEAL 308
+ E ++ +P P +GE EAL
Sbjct: 242 EAVPEEEGPTVVLNPHPSLGYKEIRKGESRSEAL 275
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 35.8 bits (81), Expect = 0.11
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 10/126 (7%)
Query: 300 EGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPR 359
E +DG+ + + R ++ST ++ + +SPD + S N R G+ S
Sbjct: 7 EEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDG-RTSPINEDIRSSGRNSPSAAST 65
Query: 360 AQVGQHVATLKEHDNSVKEEATALLRK---------ALTEECGRRSAIHSSESSCSLPSI 410
+ T+K+ VKEEA++ L+ + TEE R S+ + S P+
Sbjct: 66 SSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS 125
Query: 411 LNDNSG 416
++ G
Sbjct: 126 PSEGEG 131
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 35.8 bits (81), Expect = 0.11
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 10/126 (7%)
Query: 300 EGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPR 359
E +DG+ + + R ++ST ++ + +SPD + S N R G+ S
Sbjct: 561 EEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDG-RTSPINEDIRSSGRNSPSAAST 619
Query: 360 AQVGQHVATLKEHDNSVKEEATALLRK---------ALTEECGRRSAIHSSESSCSLPSI 410
+ T+K+ VKEEA++ L+ + TEE R S+ + S P+
Sbjct: 620 SSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS 679
Query: 411 LNDNSG 416
++ G
Sbjct: 680 PSEGEG 685
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 35.8 bits (81), Expect = 0.11
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 10/126 (7%)
Query: 300 EGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPR 359
E +DG+ + + R ++ST ++ + +SPD + S N R G+ S
Sbjct: 561 EEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDG-RTSPINEDIRSSGRNSPSAAST 619
Query: 360 AQVGQHVATLKEHDNSVKEEATALLRK---------ALTEECGRRSAIHSSESSCSLPSI 410
+ T+K+ VKEEA++ L+ + TEE R S+ + S P+
Sbjct: 620 SSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS 679
Query: 411 LNDNSG 416
++ G
Sbjct: 680 PSEGEG 685
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 35.4 bits (80), Expect = 0.14
Identities = 39/152 (25%), Positives = 60/152 (39%), Gaps = 19/152 (12%)
Query: 314 EQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA-----QVGQHVAT 368
E++ A + E+ LQ ++S + E +T AP EP PD + A +G+
Sbjct: 12 EEKPSASALEQPATLQEVASQEVPPELATPAPAWEPQPEPDERLEAAACEVNDLGEEEEE 71
Query: 369 LKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNS 428
+E D +E+ E+ G A +E+S P I D KP L
Sbjct: 72 EEEEDEEEEEDDD----DDELEDEGEEEASMPNENSVKEPEIRCDE------KPEDLLEE 121
Query: 429 VPTREQEVSSGCGDKSKKENVAADIPITETEA 460
T +E C + + A IP T+ EA
Sbjct: 122 PKTTSEETLEDCSEVTP----AMQIPRTKEEA 149
>gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]
Length = 778
Score = 35.4 bits (80), Expect = 0.14
Identities = 55/260 (21%), Positives = 101/260 (38%), Gaps = 14/260 (5%)
Query: 89 HSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHC 148
H R++ S ++DS + + S+ KS + + L G + P + +
Sbjct: 202 HGARRSKPFSELSDSDLEEKSSSLSPYVKSSSSHNEVFLP-GSRGPRRRKSKQHFVEKNK 260
Query: 149 LEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEV 208
L +G T S L K + P E++S R TD K + E E + +
Sbjct: 261 LTLGLPTPKTDSYLQLHNKKRGESHP--EQISYPVRVTD-KTSIQNAKEMENAAIDPEDK 317
Query: 209 EEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEES 268
+RA + ES + + P + V+DH R P K ++ + +
Sbjct: 318 WHQRAQQLKNYQEHWSQYESTKSSNVPRGQPSDMVNDHQPSRRPAKLKIRKQCKHQNGLK 377
Query: 269 WSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCIL 328
ST+ ++T S + P Q N ++ E++ ++HA V S
Sbjct: 378 SSTTEEVTASQGNQN---NPPRQQQNQNKPLDTSTKPESIVIMHASNNDVQAS------- 427
Query: 329 QTLSSPDSEKESSTNAPTRE 348
+ L S + ++ S+T AP ++
Sbjct: 428 RALRSHNLKETSNTFAPPKQ 447
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 35.0 bits (79), Expect = 0.19
Identities = 48/191 (25%), Positives = 72/191 (37%), Gaps = 18/191 (9%)
Query: 171 LNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESEN 230
+ PL E R L+ E L E E+ K P P E E+E
Sbjct: 1120 MEPPLEEESLEAKRVQGLEGPRKDLEEAGGLGTEFSELPGKSRDPWEPPREGREESEAEA 1179
Query: 231 KWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPE 290
E+ P ++ L H + P+ EE EE ++ S + ++ ++P
Sbjct: 1180 PRGAEEAFP----AETLGHTGSDAPSPWPLGSEEAEEDVPPVL-VSPSPTYTPILEDAPG 1234
Query: 291 PQPNPGGKMEGEDGI----EALKLIHAEQERVALSTEKNCILQTLSSPDSE-KESSTNAP 345
PQP G E G+ EAL + +EQE + + P E +ES +
Sbjct: 1235 PQPQAEGSQEASWGVQGRAEALGKVESEQEELGSG-------EIPEGPQEEGEESREESE 1287
Query: 346 TREPGQT-PDS 355
E G+T PDS
Sbjct: 1288 EDELGETLPDS 1298
Score = 30.4 bits (67), Expect = 4.6
Identities = 32/159 (20%), Positives = 63/159 (39%), Gaps = 9/159 (5%)
Query: 227 ESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESW-----STSSDLTISISE 281
E EN+ + SP G + L ++Q+P R +++E +E++ L E
Sbjct: 671 EKENQ--EPLRSPEVGDEEALRPLTKENQEPLRSLEDENKEAFRSLEKENQEPLKTLEEE 728
Query: 282 DDLILESPEPQPNPGGKMEGEDGIEALKLIHAE--QERVALSTEKNCILQTLSSPDSEKE 339
D I+ E + + + E E L+ + E Q R +L + L+ D E
Sbjct: 729 DQSIVRPLETENHKSLRSLEEQDQETLRTLEKETQQRRRSLGEQDQMTLRPPEKVDLEPL 788
Query: 340 SSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKE 378
S + P + + + ++ + V +K + + E
Sbjct: 789 KSLDQEIARPLENENQEFLKSLKEESVEAVKSLETEILE 827
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.122 0.336
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,706,611
Number of Sequences: 37866
Number of extensions: 1167643
Number of successful extensions: 3510
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 193
Number of HSP's that attempted gapping in prelim test: 3324
Number of HSP's gapped (non-prelim): 335
length of query: 570
length of database: 18,247,518
effective HSP length: 108
effective length of query: 462
effective length of database: 14,157,990
effective search space: 6540991380
effective search space used: 6540991380
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.