Guide to the Human Genome
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Search of human proteins with 24430212

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24430212 interleukin 23 receptor precursor [Homo sapiens]
         (629 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24430212 interleukin 23 receptor precursor [Homo sapiens]         1288   0.0  
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]    78   3e-14
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ...    74   5e-13
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ...    74   5e-13
gi|4504993 leukemia inhibitory factor receptor precursor [Homo s...    62   1e-09
gi|189083786 leukemia inhibitory factor receptor precursor [Homo...    62   1e-09
gi|27437045 colony stimulating factor 3 receptor isoform d precu...    59   1e-08
gi|24496783 colony stimulating factor 3 receptor isoform c precu...    59   1e-08
gi|27437042 colony stimulating factor 3 receptor isoform b precu...    59   1e-08
gi|4503081 colony stimulating factor 3 receptor isoform a precur...    59   1e-08
gi|115430248 gp130-like monocyte receptor [Homo sapiens]               58   3e-08
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]              57   5e-08
gi|4506107 prolactin receptor [Homo sapiens]                           47   7e-05
gi|37537696 M-phase phosphoprotein 9 [Homo sapiens]                    41   0.003
gi|51093381 leptin receptor isoform 3 [Homo sapiens]                   40   0.006
gi|51093379 leptin receptor isoform 2 [Homo sapiens]                   40   0.006
gi|40254464 leptin receptor isoform 1 [Homo sapiens]                   40   0.006
gi|156142186 cytokine receptor-like factor 3 [Homo sapiens]            37   0.055
gi|24497438 interleukin 12B precursor [Homo sapiens]                   36   0.094
gi|4759328 class I cytokine receptor [Homo sapiens]                    36   0.094
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi...    35   0.21 
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap...    35   0.21 
gi|20070195 colony stimulating factor 2 receptor alpha chain iso...    34   0.47 
gi|238908519 colony stimulating factor 2 receptor alpha chain is...    34   0.47 
gi|238908517 colony stimulating factor 2 receptor alpha chain is...    34   0.47 
gi|238908515 colony stimulating factor 2 receptor alpha chain is...    34   0.47 
gi|27437036 colony stimulating factor 2 receptor alpha chain iso...    34   0.47 
gi|27437034 colony stimulating factor 2 receptor alpha chain iso...    34   0.47 
gi|27437032 colony stimulating factor 2 receptor alpha chain iso...    34   0.47 
gi|18641360 collectin sub-family member 12 [Homo sapiens]              33   0.79 

>gi|24430212 interleukin 23 receptor precursor [Homo sapiens]
          Length = 629

 Score = 1288 bits (3334), Expect = 0.0
 Identities = 629/629 (100%), Positives = 629/629 (100%)

Query: 1   MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQ 60
           MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQ
Sbjct: 1   MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQ 60

Query: 61  PRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDIS 120
           PRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDIS
Sbjct: 61  PRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDIS 120

Query: 121 SGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYIN 180
           SGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYIN
Sbjct: 121 SGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYIN 180

Query: 181 ISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTII 240
           ISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTII
Sbjct: 181 ISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTII 240

Query: 241 YWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETG 300
           YWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETG
Sbjct: 241 YWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETG 300

Query: 301 KRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGM 360
           KRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGM
Sbjct: 301 KRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGM 360

Query: 361 IVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMN 420
           IVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMN
Sbjct: 361 IVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMN 420

Query: 421 NNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDL 480
           NNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDL
Sbjct: 421 NNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDL 480

Query: 481 NTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSL 540
           NTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSL
Sbjct: 481 NTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSL 540

Query: 541 SNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGI 600
           SNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGI
Sbjct: 541 SNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGI 600

Query: 601 VNEELPSINTYFPQNILESHFNRISLLEK 629
           VNEELPSINTYFPQNILESHFNRISLLEK
Sbjct: 601 VNEELPSINTYFPQNILESHFNRISLLEK 629


>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
          Length = 862

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 74/305 (24%), Positives = 127/305 (41%), Gaps = 30/305 (9%)

Query: 32  GHIWVEPATIFKMGMNISIYC-----QAAIKNCQPRKLHFYKNGIKERFQITR-INKTTA 85
           G + V+P+ +  +G  ++I C     Q      +  KL  YK   +  F     +N    
Sbjct: 31  GDVTVKPSHVILLGSTVNITCSLKPRQGCFHYSRRNKLILYKFDRRINFHHGHSLNSQVT 90

Query: 86  RLWYKNFLEPHASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNMTCT 145
            L     L       C   C     E  ICG +I  G  P+ P  ++C+     G + CT
Sbjct: 91  GLPLGTTL-----FVCKLACINS-DEIQICGAEIFVGVAPEQPQNLSCIQKGEQGTVACT 144

Query: 146 WNAGKLTYIDTKYVVHV---KSLETEEEQQYLTSSY----INISTDSLQGGKKYLVWVQA 198
           W  G+ T++ T+Y + +   K+L  +++ + +   Y    IN++ +S +    +   V A
Sbjct: 145 WERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCDYLDFGINLTPESPE--SNFTAKVTA 202

Query: 199 ANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTIIYWDSQTTIEKVSCEMRYK 258
            N+LG   S        DIV P      R +   A+V +  +YW  +  +  +   +RY+
Sbjct: 203 VNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEGLV--LLNRLRYR 260

Query: 259 ATTNQTWNVKEFDTNFTYV--QQSEFYLEPNIKYVFQVRCQ-ETGKRYWQPWSSLFFHKT 315
            + ++ WN+     N T    +     L+P  +Y FQ+  +    K  W  WS     +T
Sbjct: 261 PSNSRLWNM----VNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQT 316

Query: 316 PETVP 320
           PE  P
Sbjct: 317 PEEEP 321


>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
           [Homo sapiens]
          Length = 329

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 18/244 (7%)

Query: 76  QITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVI 135
           Q T IN+T + + + +    +  + C        ++  + G  I SG PP+ P  ++C++
Sbjct: 78  QYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQN-VYGITIISGLPPEKPKNLSCIV 136

Query: 136 YEYSGNMTCTWNAGKLTYIDTKYVVHV-----KSLETEEEQQYLTSSYINISTDSLQGGK 190
            E    M C W+ G+ T+++T + +       K  + + ++   TS  ++ ST      +
Sbjct: 137 NE-GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIE 195

Query: 191 KYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTI--IYWDSQT-- 246
              VWV+A NALG   S    I+ D +             IN+    +I  + W + +  
Sbjct: 196 ---VWVEAENALGKVTSD--HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250

Query: 247 TIEKVSCEMRYKATTNQTWN-VKEFDTNFTYVQQSEFYLEPNIKYVFQVRC-QETGKRYW 304
           ++  +   ++Y+     TW+ +   DT  T    +   L+P  +YVF++RC +E GK YW
Sbjct: 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310

Query: 305 QPWS 308
             WS
Sbjct: 311 SDWS 314


>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
           [Homo sapiens]
          Length = 918

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 18/244 (7%)

Query: 76  QITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVI 135
           Q T IN+T + + + +    +  + C        ++  + G  I SG PP+ P  ++C++
Sbjct: 78  QYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQN-VYGITIISGLPPEKPKNLSCIV 136

Query: 136 YEYSGNMTCTWNAGKLTYIDTKYVVHV-----KSLETEEEQQYLTSSYINISTDSLQGGK 190
            E    M C W+ G+ T+++T + +       K  + + ++   TS  ++ ST      +
Sbjct: 137 NE-GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIE 195

Query: 191 KYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTI--IYWDSQT-- 246
              VWV+A NALG   S    I+ D +             IN+    +I  + W + +  
Sbjct: 196 ---VWVEAENALGKVTSD--HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250

Query: 247 TIEKVSCEMRYKATTNQTWN-VKEFDTNFTYVQQSEFYLEPNIKYVFQVRC-QETGKRYW 304
           ++  +   ++Y+     TW+ +   DT  T    +   L+P  +YVF++RC +E GK YW
Sbjct: 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310

Query: 305 QPWS 308
             WS
Sbjct: 311 SDWS 314


>gi|4504993 leukemia inhibitory factor receptor precursor [Homo
           sapiens]
          Length = 1097

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 61/242 (25%), Positives = 98/242 (40%), Gaps = 38/242 (15%)

Query: 111 ETLICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYI----DTKYV------- 159
           E  I G  I +GYPPD P ++ C  ++    + C+WN G++T +     T Y        
Sbjct: 319 EDNIFGTVIFAGYPPDTPQQLNCETHDLK-EIICSWNPGRVTALVGPRATSYTLVESFSG 377

Query: 160 --VHVKSLETEEEQQYLTSSYINISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDI 217
             V +K  E    + Y       +    L   + Y   + A N LG  +S  L +++ + 
Sbjct: 378 KYVRLKRAEAPTNESY------QLLFQMLPNQEIYNFTLNAHNPLGRSQSTIL-VNITEK 430

Query: 218 VIPSAAVISRAETINATVPKTIIYWDSQTTIEKVS--CEMRYKATTNQTWNVKEFDTNFT 275
           V P      + + IN+T  K  + W       K++  CE+  K + +     ++ +    
Sbjct: 431 VYPHTPTSFKVKDINSTAVK--LSWHLPGNFAKINFLCEIEIKKSNSVQ---EQRNVTIK 485

Query: 276 YVQQSEFY-----LEPNIKYVFQVRCQETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHD 330
            V+ S +      L P   Y F++RC       W  WS+   H T E  P   SK    D
Sbjct: 486 GVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASP---SKG--PD 540

Query: 331 TW 332
           TW
Sbjct: 541 TW 542


>gi|189083786 leukemia inhibitory factor receptor precursor [Homo
           sapiens]
          Length = 1097

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 61/242 (25%), Positives = 98/242 (40%), Gaps = 38/242 (15%)

Query: 111 ETLICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYI----DTKYV------- 159
           E  I G  I +GYPPD P ++ C  ++    + C+WN G++T +     T Y        
Sbjct: 319 EDNIFGTVIFAGYPPDTPQQLNCETHDLK-EIICSWNPGRVTALVGPRATSYTLVESFSG 377

Query: 160 --VHVKSLETEEEQQYLTSSYINISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDI 217
             V +K  E    + Y       +    L   + Y   + A N LG  +S  L +++ + 
Sbjct: 378 KYVRLKRAEAPTNESY------QLLFQMLPNQEIYNFTLNAHNPLGRSQSTIL-VNITEK 430

Query: 218 VIPSAAVISRAETINATVPKTIIYWDSQTTIEKVS--CEMRYKATTNQTWNVKEFDTNFT 275
           V P      + + IN+T  K  + W       K++  CE+  K + +     ++ +    
Sbjct: 431 VYPHTPTSFKVKDINSTAVK--LSWHLPGNFAKINFLCEIEIKKSNSVQ---EQRNVTIK 485

Query: 276 YVQQSEFY-----LEPNIKYVFQVRCQETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHD 330
            V+ S +      L P   Y F++RC       W  WS+   H T E  P   SK    D
Sbjct: 486 GVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASP---SKG--PD 540

Query: 331 TW 332
           TW
Sbjct: 541 TW 542


>gi|27437045 colony stimulating factor 3 receptor isoform d
           precursor [Homo sapiens]
          Length = 783

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 55/233 (23%), Positives = 94/233 (40%), Gaps = 25/233 (10%)

Query: 118 DISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSS 177
           ++ +GYPP IP  ++C++   + ++ C W  G  T++ T +   +KS ++    Q    S
Sbjct: 116 ELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFT--LKSFKSRGNCQTQGDS 173

Query: 178 YINISTDSLQG----GKKYL-------VWVQAANALGMEESKQLQIHLDDIVIPSAAVIS 226
            ++      Q      +K+L       +WVQA NALG   S QL +   D+V     ++ 
Sbjct: 174 ILDCVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLR 233

Query: 227 RAETINATVPKTI----IYWDSQTTIEKVS--CEMRYKATTNQTWNVKEFDTNFTYVQQS 280
             +      P       + W+       ++  CE+R+K    +             +Q  
Sbjct: 234 TMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYE 293

Query: 281 EFYLEPNIKYVFQVRC-QETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDTW 332
              L P   Y  Q+RC +     +W  WS     +T E  P V     + DTW
Sbjct: 294 LCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTV-----RLDTW 341


>gi|24496783 colony stimulating factor 3 receptor isoform c
           precursor [Homo sapiens]
          Length = 863

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 55/233 (23%), Positives = 94/233 (40%), Gaps = 25/233 (10%)

Query: 118 DISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSS 177
           ++ +GYPP IP  ++C++   + ++ C W  G  T++ T +   +KS ++    Q    S
Sbjct: 116 ELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFT--LKSFKSRGNCQTQGDS 173

Query: 178 YINISTDSLQG----GKKYL-------VWVQAANALGMEESKQLQIHLDDIVIPSAAVIS 226
            ++      Q      +K+L       +WVQA NALG   S QL +   D+V     ++ 
Sbjct: 174 ILDCVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLR 233

Query: 227 RAETINATVPKTI----IYWDSQTTIEKVS--CEMRYKATTNQTWNVKEFDTNFTYVQQS 280
             +      P       + W+       ++  CE+R+K    +             +Q  
Sbjct: 234 TMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYE 293

Query: 281 EFYLEPNIKYVFQVRC-QETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDTW 332
              L P   Y  Q+RC +     +W  WS     +T E  P V     + DTW
Sbjct: 294 LCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTV-----RLDTW 341


>gi|27437042 colony stimulating factor 3 receptor isoform b
           precursor [Homo sapiens]
          Length = 769

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 55/233 (23%), Positives = 94/233 (40%), Gaps = 25/233 (10%)

Query: 118 DISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSS 177
           ++ +GYPP IP  ++C++   + ++ C W  G  T++ T +   +KS ++    Q    S
Sbjct: 116 ELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFT--LKSFKSRGNCQTQGDS 173

Query: 178 YINISTDSLQG----GKKYL-------VWVQAANALGMEESKQLQIHLDDIVIPSAAVIS 226
            ++      Q      +K+L       +WVQA NALG   S QL +   D+V     ++ 
Sbjct: 174 ILDCVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLR 233

Query: 227 RAETINATVPKTI----IYWDSQTTIEKVS--CEMRYKATTNQTWNVKEFDTNFTYVQQS 280
             +      P       + W+       ++  CE+R+K    +             +Q  
Sbjct: 234 TMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYE 293

Query: 281 EFYLEPNIKYVFQVRC-QETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDTW 332
              L P   Y  Q+RC +     +W  WS     +T E  P V     + DTW
Sbjct: 294 LCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTV-----RLDTW 341


>gi|4503081 colony stimulating factor 3 receptor isoform a precursor
           [Homo sapiens]
          Length = 836

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 55/233 (23%), Positives = 94/233 (40%), Gaps = 25/233 (10%)

Query: 118 DISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSS 177
           ++ +GYPP IP  ++C++   + ++ C W  G  T++ T +   +KS ++    Q    S
Sbjct: 116 ELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFT--LKSFKSRGNCQTQGDS 173

Query: 178 YINISTDSLQG----GKKYL-------VWVQAANALGMEESKQLQIHLDDIVIPSAAVIS 226
            ++      Q      +K+L       +WVQA NALG   S QL +   D+V     ++ 
Sbjct: 174 ILDCVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLR 233

Query: 227 RAETINATVPKTI----IYWDSQTTIEKVS--CEMRYKATTNQTWNVKEFDTNFTYVQQS 280
             +      P       + W+       ++  CE+R+K    +             +Q  
Sbjct: 234 TMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYE 293

Query: 281 EFYLEPNIKYVFQVRC-QETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDTW 332
              L P   Y  Q+RC +     +W  WS     +T E  P V     + DTW
Sbjct: 294 LCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTV-----RLDTW 341


>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
          Length = 764

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 57/212 (26%), Positives = 86/212 (40%), Gaps = 22/212 (10%)

Query: 125 PDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYINISTD 184
           P  P+ ++CV Y Y  N+TCTW+ GK T   T+Y V       E+     T+S  + +  
Sbjct: 54  PAKPENISCVYY-YRKNLTCTWSPGKETSY-TQYTVKRTYAFGEKHDNCTTNSSTSENRA 111

Query: 185 S-------LQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPK 237
           S       +     Y + V+A N  G+ +S      L++I       I R + +      
Sbjct: 112 SCSFFLPRITIPDNYTIEVEAENGDGVIKSHMTYWRLENIAKTEPPKIFRVKPVLGIKRM 171

Query: 238 TIIYWDSQTTIEKVSCEMRYKA---TTNQT-WNVKEF-----DTNFTYVQQSEFYLEPNI 288
             I W  +  +  VS +++Y     T N T W    F     D N TY       L+P  
Sbjct: 172 IQIEW-IKPELAPVSSDLKYTLRFRTVNSTSWMEVNFAKNRKDKNQTYNLTG---LQPFT 227

Query: 289 KYVFQVRCQETGKRYWQPWSSLFFHKTPETVP 320
           +YV  +RC     ++W  WS      T E  P
Sbjct: 228 EYVIALRCAVKESKFWSDWSQEKMGMTEEEAP 259


>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
          Length = 422

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 56/230 (24%), Positives = 91/230 (39%), Gaps = 31/230 (13%)

Query: 112 TLICGKDISSGYPPDIPDEVTCVIYEYSGNM---TCTWNAGKL--TYIDTKYVVHVKSL- 165
           +++ G  +  G PP+ P  ++C    +S NM   TC W  G    T++ T Y +  K   
Sbjct: 122 SILAGSCLYVGLPPEKPVNISC----WSKNMKDLTCRWTPGAHGETFLHTNYSLKYKLRW 177

Query: 166 ----ETEEEQQYLTSSYINISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPS 221
                T EE   +     +I  D L     Y +WV+A N LG   S  L + + D+V   
Sbjct: 178 YGQDNTCEEYHTVGPHSCHIPKD-LALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTD 236

Query: 222 AAVISRAETINATVPKTIIYWDSQTTIE----KVSCEMRYKATTNQTWNVKEFDTNFTYV 277
                    +     +  + W S   ++    +   ++RY+   +  W V +  +N T  
Sbjct: 237 PPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSC 296

Query: 278 QQSEFYLEPNIKYVFQVRCQETG------KRYWQPWSSLFFHKTPETVPQ 321
           + +   L+P   Y  QVRC   G         W  WS    H T  + P+
Sbjct: 297 RLAG--LKPGTVYFVQVRCNPFGIYGSKKAGIWSEWS----HPTAASTPR 340


>gi|4506107 prolactin receptor [Homo sapiens]
          Length = 622

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 62/241 (25%), Positives = 89/241 (36%), Gaps = 43/241 (17%)

Query: 124 PPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSS---YIN 180
           PP  P+   C         TC W  G    + T Y     SL    E + L      YI 
Sbjct: 27  PPGKPEIFKCRSPNKE-TFTCWWRPGTDGGLPTNY-----SLTYHREGETLMHECPDYIT 80

Query: 181 ISTDSLQGGKKY-------LVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINA 233
              +S   GK+Y       ++ V A N +G   S +L + +  IV P   +    E    
Sbjct: 81  GGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQP 140

Query: 234 TVPKTIIY--WDSQTTIE------KVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFY-- 283
              K  ++  W   T I+       +  E+R K      W +          QQ+EF   
Sbjct: 141 EDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAG------QQTEFKIL 194

Query: 284 -LEPNIKYVFQVRCQETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDT--WNSGLTVAS 340
            L P  KY+ QVRC +    YW  WS       P T  Q+ S    +DT  W S   +++
Sbjct: 195 SLHPGQKYLVQVRC-KPDHGYWSAWS-------PATFIQIPSDFTMNDTTVWISVAVLSA 246

Query: 341 I 341
           +
Sbjct: 247 V 247


>gi|37537696 M-phase phosphoprotein 9 [Homo sapiens]
          Length = 1031

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 52/212 (24%), Positives = 90/212 (42%), Gaps = 32/212 (15%)

Query: 439 EIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPD-------LNTGYKPQISNF 491
           E+ +P  K   YKK+     E +  P+ +L   +   + P+       L+   K QIS  
Sbjct: 252 EMKLPSLKDIYYKKQR----ENKQLPERNLTSASNPNHPPEVLTLDPTLHMKPKQQISGI 307

Query: 492 LPEGSHLSNNNEIT---------SLTLKPPVDSLDSGNN-----PRLQKHPNFAFSVSSV 537
            P G   + ++ I+         S++    +DS    +N     P   K+P+     S V
Sbjct: 308 QPHGLPNALDDRISFSPDSVLEPSMSSPSDIDSFSQASNVTSQLPGFPKYPSHT-KASPV 366

Query: 538 NSLSNTIFLGEL---SLILNQGECSSPDIQ-NSVEEETTMLLENDSPSETIPEQTLLPDE 593
           +S  N  F  E    S   +    +S DI  N+V+EE T+++ + S S++    T   + 
Sbjct: 367 DSWKNQTFQNESRTSSTFPSVYTITSNDISVNTVDEENTVMVASASVSQSQLPGTA--NS 424

Query: 594 FVSCLGIVNEELPSINTYFPQNILESHFNRIS 625
              C+ + + E P I +   QN+ E H   I+
Sbjct: 425 VPECISLTSLEDPVILSKIRQNLKEKHARHIA 456


>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
          Length = 958

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 65/307 (21%), Positives = 121/307 (39%), Gaps = 44/307 (14%)

Query: 34  IWVEPATIFKMGMNISIYCQAAIKN-CQPRKLHFYKNGIKERF---QITRINKTTARLWY 89
           I+  P  +  +G N+S +C    +N   P K   +   + E+    Q   ++   +++ +
Sbjct: 334 IYFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTF 393

Query: 90  KNFLEP-------HASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNM 142
            N  E        + ++YC   C +H      C    +  Y  D+   ++C    Y   M
Sbjct: 394 FNLNETKPRGKFTYDAVYC---CNEHE-----CHHRYAELYVIDVNINISCETDGYLTKM 445

Query: 143 TCTWNAGKLTYI-----------DTKYVVHVKSLE--TEEEQQYLTS-SYINISTDSLQG 188
           TC W+   +  +            + Y   + S+   +E +  YL S  +       +  
Sbjct: 446 TCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFL 505

Query: 189 GKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAE-TINATVPKTIIYWDSQTT 247
              Y +W++  ++LG  +S    +  D +V P      +AE TIN  + K  I W+    
Sbjct: 506 LSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK--ISWEKPVF 563

Query: 248 IE-KVSCEMRYKATTNQT-WNVKEFDTNFTYVQQSEFYLEPNI--KYVFQVRCQE-TGKR 302
            E  +  ++RY  +  +  W + E    +    +S     P++   Y  QVRC+   G  
Sbjct: 564 PENNLQFQIRYGLSGKEVQWKMYEV---YDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLG 620

Query: 303 YWQPWSS 309
           YW  WS+
Sbjct: 621 YWSNWSN 627


>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
          Length = 896

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 65/307 (21%), Positives = 121/307 (39%), Gaps = 44/307 (14%)

Query: 34  IWVEPATIFKMGMNISIYCQAAIKN-CQPRKLHFYKNGIKERF---QITRINKTTARLWY 89
           I+  P  +  +G N+S +C    +N   P K   +   + E+    Q   ++   +++ +
Sbjct: 334 IYFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTF 393

Query: 90  KNFLEP-------HASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNM 142
            N  E        + ++YC   C +H      C    +  Y  D+   ++C    Y   M
Sbjct: 394 FNLNETKPRGKFTYDAVYC---CNEHE-----CHHRYAELYVIDVNINISCETDGYLTKM 445

Query: 143 TCTWNAGKLTYI-----------DTKYVVHVKSLE--TEEEQQYLTS-SYINISTDSLQG 188
           TC W+   +  +            + Y   + S+   +E +  YL S  +       +  
Sbjct: 446 TCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFL 505

Query: 189 GKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAE-TINATVPKTIIYWDSQTT 247
              Y +W++  ++LG  +S    +  D +V P      +AE TIN  + K  I W+    
Sbjct: 506 LSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK--ISWEKPVF 563

Query: 248 IE-KVSCEMRYKATTNQT-WNVKEFDTNFTYVQQSEFYLEPNI--KYVFQVRCQE-TGKR 302
            E  +  ++RY  +  +  W + E    +    +S     P++   Y  QVRC+   G  
Sbjct: 564 PENNLQFQIRYGLSGKEVQWKMYEV---YDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLG 620

Query: 303 YWQPWSS 309
           YW  WS+
Sbjct: 621 YWSNWSN 627


>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
          Length = 1165

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 65/307 (21%), Positives = 121/307 (39%), Gaps = 44/307 (14%)

Query: 34  IWVEPATIFKMGMNISIYCQAAIKN-CQPRKLHFYKNGIKERF---QITRINKTTARLWY 89
           I+  P  +  +G N+S +C    +N   P K   +   + E+    Q   ++   +++ +
Sbjct: 334 IYFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTF 393

Query: 90  KNFLEP-------HASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNM 142
            N  E        + ++YC   C +H      C    +  Y  D+   ++C    Y   M
Sbjct: 394 FNLNETKPRGKFTYDAVYC---CNEHE-----CHHRYAELYVIDVNINISCETDGYLTKM 445

Query: 143 TCTWNAGKLTYI-----------DTKYVVHVKSLE--TEEEQQYLTS-SYINISTDSLQG 188
           TC W+   +  +            + Y   + S+   +E +  YL S  +       +  
Sbjct: 446 TCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFL 505

Query: 189 GKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAE-TINATVPKTIIYWDSQTT 247
              Y +W++  ++LG  +S    +  D +V P      +AE TIN  + K  I W+    
Sbjct: 506 LSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLK--ISWEKPVF 563

Query: 248 IE-KVSCEMRYKATTNQT-WNVKEFDTNFTYVQQSEFYLEPNI--KYVFQVRCQE-TGKR 302
            E  +  ++RY  +  +  W + E    +    +S     P++   Y  QVRC+   G  
Sbjct: 564 PENNLQFQIRYGLSGKEVQWKMYEV---YDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLG 620

Query: 303 YWQPWSS 309
           YW  WS+
Sbjct: 621 YWSNWSN 627


>gi|156142186 cytokine receptor-like factor 3 [Homo sapiens]
          Length = 442

 Score = 37.0 bits (84), Expect = 0.055
 Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 10/61 (16%)

Query: 283 YLEPNIKYVFQVRCQETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASIS 342
           +++PN+ Y F+V  +  G++ W PWS          VPQ+         W +G    S+S
Sbjct: 238 HIDPNVDYQFRVCARGDGRQEWSPWS----------VPQIGHSTLVPHEWTAGFEGYSLS 287

Query: 343 T 343
           +
Sbjct: 288 S 288


>gi|24497438 interleukin 12B precursor [Homo sapiens]
          Length = 328

 Score = 36.2 bits (82), Expect = 0.094
 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 8/89 (8%)

Query: 133 CVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYINISTDSLQGGKK- 191
           C    YSG  TC W    LT I T     VKS     + Q +T     +S + ++G  K 
Sbjct: 131 CEAKNYSGRFTCWW----LTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKE 186

Query: 192 --YLVWVQAANAL-GMEESKQLQIHLDDI 217
             Y V  Q  +A    EES  +++ +D +
Sbjct: 187 YEYSVECQEDSACPAAEESLPIEVMVDAV 215


>gi|4759328 class I cytokine receptor [Homo sapiens]
          Length = 636

 Score = 36.2 bits (82), Expect = 0.094
 Identities = 45/209 (21%), Positives = 79/209 (37%), Gaps = 29/209 (13%)

Query: 140 GNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTS-----SYINISTDSLQGGKKYLV 194
           G++ C+W    L  +     +H++S +    +    +     S++ I  + L    K LV
Sbjct: 48  GDLNCSWEP--LGDLGAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMSDKLLV 105

Query: 195 WVQAANALGMEESKQLQIHLDDIVIPSAAVI------SRAETINATVPKTIIYWDSQTTI 248
           W   A   G      + ++L+  + P+A  +      S  + + ATV      W S   +
Sbjct: 106 WGTKA---GQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVL 162

Query: 249 EKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFY-LEPNIKYVFQVRCQ-ETGKRYWQP 306
               C+  Y+      W + E +     +   E   LE    Y    RC+ E  +  W  
Sbjct: 163 ---ICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGE 219

Query: 307 WSSLFFHKTPETVPQVTSKAFQHDTWNSG 335
           WS +   +TP + P+        D W SG
Sbjct: 220 WSPILSFQTPPSAPK--------DVWVSG 240


>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
           sapiens]
          Length = 468

 Score = 35.0 bits (79), Expect = 0.21
 Identities = 43/201 (21%), Positives = 77/201 (38%), Gaps = 22/201 (10%)

Query: 124 PPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLET------EEEQQYLTSS 177
           PP+ P +++C       N+ C W       + TK V+ V+  +       +E  QY   S
Sbjct: 113 PPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171

Query: 178 YINISTDSLQGGKK--YLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATV 235
                  ++  G    Y+V +  A+++G + SK        I+ P          +    
Sbjct: 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231

Query: 236 PKTIIYWDS----QTTIEKVSCEMRYKA---TTNQTWNVKEFDTNFTYVQQSEFYLEPNI 288
               + W       ++  ++  E+RY+A    T  TW VK+   +              +
Sbjct: 232 RWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWS-----GL 286

Query: 289 KYVFQVRCQET-GKRYWQPWS 308
           ++V Q+R QE  G+  W  WS
Sbjct: 287 RHVVQLRAQEEFGQGEWSEWS 307


>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
           sapiens]
          Length = 365

 Score = 35.0 bits (79), Expect = 0.21
 Identities = 43/201 (21%), Positives = 77/201 (38%), Gaps = 22/201 (10%)

Query: 124 PPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLET------EEEQQYLTSS 177
           PP+ P +++C       N+ C W       + TK V+ V+  +       +E  QY   S
Sbjct: 113 PPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171

Query: 178 YINISTDSLQGGKK--YLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATV 235
                  ++  G    Y+V +  A+++G + SK        I+ P          +    
Sbjct: 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231

Query: 236 PKTIIYWDS----QTTIEKVSCEMRYKA---TTNQTWNVKEFDTNFTYVQQSEFYLEPNI 288
               + W       ++  ++  E+RY+A    T  TW VK+   +              +
Sbjct: 232 RWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWS-----GL 286

Query: 289 KYVFQVRCQET-GKRYWQPWS 308
           ++V Q+R QE  G+  W  WS
Sbjct: 287 RHVVQLRAQEEFGQGEWSEWS 307


>gi|20070195 colony stimulating factor 2 receptor alpha chain
           isoform a precursor [Homo sapiens]
          Length = 400

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 42/208 (20%), Positives = 78/208 (37%), Gaps = 29/208 (13%)

Query: 120 SSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEE---QQYLTS 176
           +SG         +C IY  +  M CTW  G     D +Y +++++ +   E     Y+  
Sbjct: 113 NSGREGTAAQNFSCFIYN-ADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQD 171

Query: 177 S--YINISTDSLQG--GKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETIN 232
           S  ++    D+L G   + Y +    +  +G++    L   LD   I      S   T+ 
Sbjct: 172 SGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSL---LDTKKIERFNPPSNV-TVR 227

Query: 233 ATVPKTIIYWDSQTTIEKVS-CEMRYK----------ATTNQTWNVK-EFDTNFTYVQQS 280
                 ++ W    T +K+S  + +Y+           T N   NV  + +  + +    
Sbjct: 228 CNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSS- 286

Query: 281 EFYLEPNIKYVFQVRCQETGKRYWQPWS 308
               EP  K+  ++R  +     W  WS
Sbjct: 287 ----EPRAKHSVKIRAADVRILNWSSWS 310


>gi|238908519 colony stimulating factor 2 receptor alpha chain
           isoform g precursor [Homo sapiens]
          Length = 410

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 42/208 (20%), Positives = 78/208 (37%), Gaps = 29/208 (13%)

Query: 120 SSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEE---QQYLTS 176
           +SG         +C IY  +  M CTW  G     D +Y +++++ +   E     Y+  
Sbjct: 113 NSGREGTAAQNFSCFIYN-ADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQD 171

Query: 177 S--YINISTDSLQG--GKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETIN 232
           S  ++    D+L G   + Y +    +  +G++    L   LD   I      S   T+ 
Sbjct: 172 SGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSL---LDTKKIERFNPPSNV-TVR 227

Query: 233 ATVPKTIIYWDSQTTIEKVS-CEMRYK----------ATTNQTWNVK-EFDTNFTYVQQS 280
                 ++ W    T +K+S  + +Y+           T N   NV  + +  + +    
Sbjct: 228 CNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSS- 286

Query: 281 EFYLEPNIKYVFQVRCQETGKRYWQPWS 308
               EP  K+  ++R  +     W  WS
Sbjct: 287 ----EPRAKHSVKIRAADVRILNWSSWS 310


>gi|238908517 colony stimulating factor 2 receptor alpha chain
           isoform f precursor [Homo sapiens]
          Length = 434

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 42/208 (20%), Positives = 78/208 (37%), Gaps = 29/208 (13%)

Query: 120 SSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEE---QQYLTS 176
           +SG         +C IY  +  M CTW  G     D +Y +++++ +   E     Y+  
Sbjct: 113 NSGREGTAAQNFSCFIYN-ADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQD 171

Query: 177 S--YINISTDSLQG--GKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETIN 232
           S  ++    D+L G   + Y +    +  +G++    L   LD   I      S   T+ 
Sbjct: 172 SGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSL---LDTKKIERFNPPSNV-TVR 227

Query: 233 ATVPKTIIYWDSQTTIEKVS-CEMRYK----------ATTNQTWNVK-EFDTNFTYVQQS 280
                 ++ W    T +K+S  + +Y+           T N   NV  + +  + +    
Sbjct: 228 CNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSS- 286

Query: 281 EFYLEPNIKYVFQVRCQETGKRYWQPWS 308
               EP  K+  ++R  +     W  WS
Sbjct: 287 ----EPRAKHSVKIRAADVRILNWSSWS 310


>gi|238908515 colony stimulating factor 2 receptor alpha chain
           isoform a precursor [Homo sapiens]
          Length = 400

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 42/208 (20%), Positives = 78/208 (37%), Gaps = 29/208 (13%)

Query: 120 SSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEE---QQYLTS 176
           +SG         +C IY  +  M CTW  G     D +Y +++++ +   E     Y+  
Sbjct: 113 NSGREGTAAQNFSCFIYN-ADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQD 171

Query: 177 S--YINISTDSLQG--GKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETIN 232
           S  ++    D+L G   + Y +    +  +G++    L   LD   I      S   T+ 
Sbjct: 172 SGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSL---LDTKKIERFNPPSNV-TVR 227

Query: 233 ATVPKTIIYWDSQTTIEKVS-CEMRYK----------ATTNQTWNVK-EFDTNFTYVQQS 280
                 ++ W    T +K+S  + +Y+           T N   NV  + +  + +    
Sbjct: 228 CNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSS- 286

Query: 281 EFYLEPNIKYVFQVRCQETGKRYWQPWS 308
               EP  K+  ++R  +     W  WS
Sbjct: 287 ----EPRAKHSVKIRAADVRILNWSSWS 310


>gi|27437036 colony stimulating factor 2 receptor alpha chain
           isoform c precursor [Homo sapiens]
          Length = 333

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 42/208 (20%), Positives = 78/208 (37%), Gaps = 29/208 (13%)

Query: 120 SSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEE---QQYLTS 176
           +SG         +C IY  +  M CTW  G     D +Y +++++ +   E     Y+  
Sbjct: 113 NSGREGTAAQNFSCFIYN-ADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQD 171

Query: 177 S--YINISTDSLQG--GKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETIN 232
           S  ++    D+L G   + Y +    +  +G++    L   LD   I      S   T+ 
Sbjct: 172 SGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSL---LDTKKIERFNPPSNV-TVR 227

Query: 233 ATVPKTIIYWDSQTTIEKVS-CEMRYK----------ATTNQTWNVK-EFDTNFTYVQQS 280
                 ++ W    T +K+S  + +Y+           T N   NV  + +  + +    
Sbjct: 228 CNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSS- 286

Query: 281 EFYLEPNIKYVFQVRCQETGKRYWQPWS 308
               EP  K+  ++R  +     W  WS
Sbjct: 287 ----EPRAKHSVKIRAADVRILNWSSWS 310


>gi|27437034 colony stimulating factor 2 receptor alpha chain
           isoform b precursor [Homo sapiens]
          Length = 377

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 42/208 (20%), Positives = 78/208 (37%), Gaps = 29/208 (13%)

Query: 120 SSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEE---QQYLTS 176
           +SG         +C IY  +  M CTW  G     D +Y +++++ +   E     Y+  
Sbjct: 113 NSGREGTAAQNFSCFIYN-ADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQD 171

Query: 177 S--YINISTDSLQG--GKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETIN 232
           S  ++    D+L G   + Y +    +  +G++    L   LD   I      S   T+ 
Sbjct: 172 SGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSL---LDTKKIERFNPPSNV-TVR 227

Query: 233 ATVPKTIIYWDSQTTIEKVS-CEMRYK----------ATTNQTWNVK-EFDTNFTYVQQS 280
                 ++ W    T +K+S  + +Y+           T N   NV  + +  + +    
Sbjct: 228 CNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSS- 286

Query: 281 EFYLEPNIKYVFQVRCQETGKRYWQPWS 308
               EP  K+  ++R  +     W  WS
Sbjct: 287 ----EPRAKHSVKIRAADVRILNWSSWS 310


>gi|27437032 colony stimulating factor 2 receptor alpha chain
           isoform a precursor [Homo sapiens]
          Length = 400

 Score = 33.9 bits (76), Expect = 0.47
 Identities = 42/208 (20%), Positives = 78/208 (37%), Gaps = 29/208 (13%)

Query: 120 SSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEE---QQYLTS 176
           +SG         +C IY  +  M CTW  G     D +Y +++++ +   E     Y+  
Sbjct: 113 NSGREGTAAQNFSCFIYN-ADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQD 171

Query: 177 S--YINISTDSLQG--GKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETIN 232
           S  ++    D+L G   + Y +    +  +G++    L   LD   I      S   T+ 
Sbjct: 172 SGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSL---LDTKKIERFNPPSNV-TVR 227

Query: 233 ATVPKTIIYWDSQTTIEKVS-CEMRYK----------ATTNQTWNVK-EFDTNFTYVQQS 280
                 ++ W    T +K+S  + +Y+           T N   NV  + +  + +    
Sbjct: 228 CNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSS- 286

Query: 281 EFYLEPNIKYVFQVRCQETGKRYWQPWS 308
               EP  K+  ++R  +     W  WS
Sbjct: 287 ----EPRAKHSVKIRAADVRILNWSSWS 310


>gi|18641360 collectin sub-family member 12 [Homo sapiens]
          Length = 742

 Score = 33.1 bits (74), Expect = 0.79
 Identities = 50/240 (20%), Positives = 97/240 (40%), Gaps = 30/240 (12%)

Query: 400 IPNMKNSNVVKMLQENSELMNN------NSSEQVLYVDPMITEIKEIFIPEHKPTDYKKE 453
           I N+ N N+ ++ Q N  L+ N      ++S+ +  +      ++++F+   K TD+ KE
Sbjct: 203 IMNLNNLNLTQVQQRN--LITNLQRSVDDTSQAIQRIKNDFQNLQQVFLQAKKDTDWLKE 260

Query: 454 NTGPLETRDYPQNSLFDNTTVVYIPDLNTGYKPQISNFLPEGSHLSNNNEITSLTLKPPV 513
               L+T     NS         + D+N+    Q+++F  +  +++  ++     LK   
Sbjct: 261 KVQSLQTL-AANNSALAKANNDTLEDMNS----QLNSFTGQMENITTISQANEQNLKDLQ 315

Query: 514 DSLDSGNNPRLQKHPNF-----AFSVSSVNSLSNTIF----LGELSLILNQGECSSPDIQ 564
           D      N    K          F    VN +SN  +    L  L+  LN+   +  D  
Sbjct: 316 DLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTLTSNLNEVRTTCTDTL 375

Query: 565 NSVEEETTML------LENDSPSETIPEQTLLP--DEFVSCLGIVNEELPSINTYFPQNI 616
               ++ T L      +  DS S  + +  +    D  V+ L ++ EE+  +++   Q I
Sbjct: 376 TKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVIMEEMKLVDSKHGQLI 435


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,942,536
Number of Sequences: 37866
Number of extensions: 1071149
Number of successful extensions: 2847
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 2800
Number of HSP's gapped (non-prelim): 71
length of query: 629
length of database: 18,247,518
effective HSP length: 108
effective length of query: 521
effective length of database: 14,157,990
effective search space: 7376312790
effective search space used: 7376312790
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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