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Search of human proteins with 24430163
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24430163 peripheral myelin protein 22 [Homo sapiens]
(160 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505907 peripheral myelin protein 22 [Homo sapiens] 322 7e-89
gi|24430165 peripheral myelin protein 22 [Homo sapiens] 322 7e-89
gi|24430163 peripheral myelin protein 22 [Homo sapiens] 322 7e-89
gi|4503563 epithelial membrane protein 3 [Homo sapiens] 134 3e-32
gi|4503561 epithelial membrane protein 2 [Homo sapiens] 132 1e-31
gi|4503559 epithelial membrane protein 1 [Homo sapiens] 127 3e-30
gi|239747698 PREDICTED: similar to hCG1784039 [Homo sapiens] 76 1e-14
gi|22748765 claudin domain containing 2 [Homo sapiens] 49 1e-06
gi|183979973 claudin 19 isoform a [Homo sapiens] 49 2e-06
gi|183979975 claudin 19 isoform b [Homo sapiens] 49 2e-06
gi|7656981 claudin 15 [Homo sapiens] 45 2e-05
gi|169211272 PREDICTED: germ cell-specific gene 1-like protein 2... 44 5e-05
gi|169211660 PREDICTED: germ cell-specific gene 1-like protein 2... 44 5e-05
gi|169210878 PREDICTED: germ cell-specific gene 1-like protein 2... 44 5e-05
gi|5921465 claudin 10 isoform b [Homo sapiens] 44 5e-05
gi|33598916 claudin 10 isoform a [Homo sapiens] 44 5e-05
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ... 43 1e-04
gi|169163665 PREDICTED: similar to hCG1784039 [Homo sapiens] 41 4e-04
gi|169163222 PREDICTED: hypothetical protein LOC391359 [Homo sap... 41 4e-04
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 41 5e-04
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 40 7e-04
gi|13899273 transmembrane protein 47 [Homo sapiens] 39 0.002
gi|31377722 PERP, TP53 apoptosis effector [Homo sapiens] 38 0.003
gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1 [... 37 0.007
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 37 0.009
gi|22027551 voltage-dependent calcium channel gamma-5 subunit is... 36 0.012
gi|4502877 claudin 4 [Homo sapiens] 36 0.016
gi|157951718 GSG1-like isoform 1 [Homo sapiens] 36 0.016
gi|93588657 claudin domain containing 1 protein isoform d [Homo ... 35 0.021
gi|93588650 claudin domain containing 1 protein isoform a [Homo ... 35 0.021
>gi|4505907 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 322 bits (826), Expect = 7e-89
Identities = 160/160 (100%), Positives = 160/160 (100%)
Query: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 60
MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE
Sbjct: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 60
Query: 61 WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR 120
WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR
Sbjct: 61 WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR 120
Query: 121 HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160
HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE
Sbjct: 121 HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160
>gi|24430165 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 322 bits (826), Expect = 7e-89
Identities = 160/160 (100%), Positives = 160/160 (100%)
Query: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 60
MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE
Sbjct: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 60
Query: 61 WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR 120
WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR
Sbjct: 61 WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR 120
Query: 121 HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160
HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE
Sbjct: 121 HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160
>gi|24430163 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 322 bits (826), Expect = 7e-89
Identities = 160/160 (100%), Positives = 160/160 (100%)
Query: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 60
MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE
Sbjct: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 60
Query: 61 WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR 120
WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR
Sbjct: 61 WLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR 120
Query: 121 HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160
HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE
Sbjct: 121 HPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160
>gi|4503563 epithelial membrane protein 3 [Homo sapiens]
Length = 163
Score = 134 bits (338), Expect = 3e-32
Identities = 71/164 (43%), Positives = 103/164 (62%), Gaps = 5/164 (3%)
Query: 1 MLLLLLSIIVLHVAVLVLLFVSTI-VSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPN 59
M LLLL + LH+ +L+LLFV+T+ S W + + +LW +C+ ++ C + S N
Sbjct: 1 MSLLLLVVSALHILILILLFVATLDKSWWTLPGKESLNLWYDCTWNNDTKTWACSNVSEN 60
Query: 60 EWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTV 119
WL++VQ M+LS+I LS LF QL+T+ +GG FY TG+ Q+ + V + A IY +
Sbjct: 61 GWLKAVQVLMVLSLILCCLSFILFMFQLYTMRRGGLFYATGLCQLCTSVAVFTGALIYAI 120
Query: 120 RHPEWHLNS---DYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160
H E L S+G+ + LAWVAFPLAL+SG+IY+ LRKRE
Sbjct: 121 -HAEEILEKHPRGGSFGYCFALAWVAFPLALVSGIIYIHLRKRE 163
>gi|4503561 epithelial membrane protein 2 [Homo sapiens]
Length = 167
Score = 132 bits (332), Expect = 1e-31
Identities = 73/170 (42%), Positives = 108/170 (63%), Gaps = 13/170 (7%)
Query: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNE 60
ML+LL II H+ LLF++T+ + W VG+ D+W+ C+ +++ V + S E
Sbjct: 1 MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTV---INDSFQE 57
Query: 61 W--LQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYT 118
+ LQ+VQATMILS I ++ F+F QLF L +G RF +T I Q+++ LCVM AA+IYT
Sbjct: 58 YSTLQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYT 117
Query: 119 VRHPEWH--------LNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160
R + H + + SYG++YILAWVAF +SG++Y+ILRKR+
Sbjct: 118 DRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK 167
>gi|4503559 epithelial membrane protein 1 [Homo sapiens]
Length = 157
Score = 127 bits (320), Expect = 3e-30
Identities = 64/161 (39%), Positives = 104/161 (64%), Gaps = 6/161 (3%)
Query: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGN--GHATDLWQNCSTSSSGNVHHCFSSSP 58
ML+LL I V+H+A +++LFVSTI + W+V N + LW+NC+ S + S +
Sbjct: 1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSD---SLSYAS 57
Query: 59 NEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYT 118
+ L++VQA MILSIIF +++L +F QLFT+ KG RF+++G ++ LC++ +IYT
Sbjct: 58 EDALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYT 117
Query: 119 VRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKR 159
H + Y +G++YIL W+ F + + GV+Y++LRK+
Sbjct: 118 -SHYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK 157
>gi|239747698 PREDICTED: similar to hCG1784039 [Homo sapiens]
Length = 161
Score = 75.9 bits (185), Expect = 1e-14
Identities = 52/173 (30%), Positives = 88/173 (50%), Gaps = 25/173 (14%)
Query: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHC----FSS 56
ML+LL + H+ LLF++TI + W VGN D+W+ C+ ++ V + +S
Sbjct: 1 MLVLLTFTVAFHITSAALLFIATIDNAWWVGNEFFADVWRICTKNTKCTVINDSFKEYSM 60
Query: 57 SPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQIL-----AGLCVM 111
WL T ++ ++ + L ++ T + I ++L + LC+M
Sbjct: 61 GRARWL-----TPVIPALWEAEACGLXGQEIETS-------LANIMKLLHHATMSYLCLM 108
Query: 112 SAAAIYTVRHPE----WHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160
AA+IYT R E ++L + SYG++YILAWVAF +S ++Y+I + E
Sbjct: 109 IAASIYTDRRDETTDFYYLTKEGSYGYSYILAWVAFAFTFISSMMYLITEEAE 161
>gi|22748765 claudin domain containing 2 [Homo sapiens]
Length = 167
Score = 49.3 bits (116), Expect = 1e-06
Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 11/148 (7%)
Query: 9 IVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQ-A 67
I+L + VL+ +ST + W + LWQ C+ H SS P + +V A
Sbjct: 12 ILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECN-------HGICSSIPCQTTLAVTVA 64
Query: 68 TMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLN 127
M+L++ ++ + + + R T F L GL +++A YTV++ W N
Sbjct: 65 CMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKN-AWKNN 123
Query: 128 SDYSYGFAYILAWVAFPLALLSGVIYVI 155
+S+ +Y W+A P ++L+G +++
Sbjct: 124 VFFSW--SYFSGWLALPFSILAGFCFLL 149
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 48.9 bits (115), Expect = 2e-06
Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 27/159 (16%)
Query: 19 LFVSTIVSQW----------IVGNGHATDLWQNCSTSSSGNVHHCFSSSP---NEWLQSV 65
+ ST + QW I G LW +C++ S+G V S + +QS
Sbjct: 21 IIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKLYDSLLALDGHIQSA 80
Query: 66 QATMILSIIFSILSLFLFFCQLFTLTKG-------GRFYITG-IFQILAGLCVMSAAAIY 117
+A M+++++ +++ L + G GR I G ILAGLC ++A + Y
Sbjct: 81 RALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALFILAGLCTLTAVSWY 140
Query: 118 TVR------HPEWHLNSDYSYGFAYILAWVAFPLALLSG 150
+P +N+ Y +G A + W + LA+L G
Sbjct: 141 ATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGG 179
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 48.9 bits (115), Expect = 2e-06
Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 27/159 (16%)
Query: 19 LFVSTIVSQW----------IVGNGHATDLWQNCSTSSSGNVHHCFSSSP---NEWLQSV 65
+ ST + QW I G LW +C++ S+G V S + +QS
Sbjct: 21 IIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKLYDSLLALDGHIQSA 80
Query: 66 QATMILSIIFSILSLFLFFCQLFTLTKG-------GRFYITG-IFQILAGLCVMSAAAIY 117
+A M+++++ +++ L + G GR I G ILAGLC ++A + Y
Sbjct: 81 RALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALFILAGLCTLTAVSWY 140
Query: 118 TVR------HPEWHLNSDYSYGFAYILAWVAFPLALLSG 150
+P +N+ Y +G A + W + LA+L G
Sbjct: 141 ATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGG 179
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 45.4 bits (106), Expect = 2e-05
Identities = 41/148 (27%), Positives = 64/148 (43%), Gaps = 18/148 (12%)
Query: 21 VSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFS----SSPNEWLQSVQATMILSIIFS 76
VST+ I N +LW +C+T S G V++C+ + + ++Q+ +A MI +I+
Sbjct: 31 VSTVHGNVITTNTIFENLWFSCATDSLG-VYNCWEFPSMLALSGYIQACRALMITAILLG 89
Query: 77 ILSLFLFFCQLFTLTKGG--------RFYITGIFQILAGLCVMSAAAIYTVR-----HPE 123
L L L L GG G ILAG+C M A + Y
Sbjct: 90 FLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHILAGICGMVAISWYAFNITRDFFDP 149
Query: 124 WHLNSDYSYGFAYILAWVAFPLALLSGV 151
+ + Y G A L W A +++L G+
Sbjct: 150 LYPGTKYELGPALYLGWSASLISILGGL 177
>gi|169211272 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 44.3 bits (103), Expect = 5e-05
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 21/153 (13%)
Query: 18 LLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSS---PNE-----WLQSVQATM 69
+L++ + + G LWQ+C S +G C S P E WL
Sbjct: 72 VLYIWELGDDKFIQRGFHVGLWQSCEESLNGEDEKCRSFRSVVPAEEQGVLWLSI--GGE 129
Query: 70 ILSIIFSILSLFLFFCQLFTLTKGGRFY----ITGIFQILAGLCVMSAAAIYTVRH---- 121
+L I+ + S L ++ + G + + IF +LAGL M A +YT
Sbjct: 130 VLDIVLILTSAILLGSRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVAHMMYTTIFQITV 189
Query: 122 ---PEWHLNSDYSYGFAYILAWVAFPLALLSGV 151
PE + YG++Y LAW +F L L V
Sbjct: 190 NLGPEDWKPQTWDYGWSYCLAWGSFALCLAVSV 222
>gi|169211660 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 44.3 bits (103), Expect = 5e-05
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 21/153 (13%)
Query: 18 LLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSS---PNE-----WLQSVQATM 69
+L++ + + G LWQ+C S +G C S P E WL
Sbjct: 72 VLYIWELGDDKFIQRGFHVGLWQSCEESLNGEDEKCRSFRSVVPAEEQGVLWLSI--GGE 129
Query: 70 ILSIIFSILSLFLFFCQLFTLTKGGRFY----ITGIFQILAGLCVMSAAAIYTVRH---- 121
+L I+ + S L ++ + G + + IF +LAGL M A +YT
Sbjct: 130 VLDIVLILTSAILLGSRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVAHMMYTTIFQITV 189
Query: 122 ---PEWHLNSDYSYGFAYILAWVAFPLALLSGV 151
PE + YG++Y LAW +F L L V
Sbjct: 190 NLGPEDWKPQTWDYGWSYCLAWGSFALCLAVSV 222
>gi|169210878 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 44.3 bits (103), Expect = 5e-05
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 21/153 (13%)
Query: 18 LLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSS---PNE-----WLQSVQATM 69
+L++ + + G LWQ+C S +G C S P E WL
Sbjct: 72 VLYIWELGDDKFIQRGFHVGLWQSCEESLNGEDEKCRSFRSVVPAEEQGVLWLSI--GGE 129
Query: 70 ILSIIFSILSLFLFFCQLFTLTKGGRFY----ITGIFQILAGLCVMSAAAIYTVRH---- 121
+L I+ + S L ++ + G + + IF +LAGL M A +YT
Sbjct: 130 VLDIVLILTSAILLGSRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVAHMMYTTIFQITV 189
Query: 122 ---PEWHLNSDYSYGFAYILAWVAFPLALLSGV 151
PE + YG++Y LAW +F L L V
Sbjct: 190 NLGPEDWKPQTWDYGWSYCLAWGSFALCLAVSV 222
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 44.3 bits (103), Expect = 5e-05
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 17/149 (11%)
Query: 21 VSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHC--FSS--SPNEWLQSVQATMILSIIFS 76
VSTI I + +LW+ C T S+G V +C F S + + ++Q+ + MI ++
Sbjct: 32 VSTIDGTVITTATYWANLWKACVTDSTG-VSNCKDFPSMLALDGYIQACRGLMIAAVSLG 90
Query: 77 IL-SLFLFFCQLFTLTKGGR------FYITGIFQILAGLCVMSAAAIY-----TVRHPEW 124
S+F F T G + GI IL+GLC M+ ++Y T
Sbjct: 91 FFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPL 150
Query: 125 HLNSDYSYGFAYILAWVAFPLALLSGVIY 153
+ Y G A + W L ++ GVI+
Sbjct: 151 FVEQKYELGAALFIGWAGASLCIIGGVIF 179
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 44.3 bits (103), Expect = 5e-05
Identities = 36/147 (24%), Positives = 59/147 (40%), Gaps = 20/147 (13%)
Query: 22 STIVSQWIVGNGHATDLWQNCSTSSSGNVH---HCFSSSPNEWLQSVQATMILSIIFSIL 78
S I + W+ LW NC+ ++ G+ H H ++Q+ + MI ++
Sbjct: 36 SVITATWVYQG-----LWMNCAGNALGSFHCRPHFTIFKVAGYIQACRGLMIAAVSLGFF 90
Query: 79 -SLFLFFCQLFTLTKGGR------FYITGIFQILAGLCVMSAAAIY-----TVRHPEWHL 126
S+F F T G + GI IL+GLC M+ ++Y T +
Sbjct: 91 GSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFV 150
Query: 127 NSDYSYGFAYILAWVAFPLALLSGVIY 153
Y G A + W L ++ GVI+
Sbjct: 151 EQKYELGAALFIGWAGASLCIIGGVIF 177
>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
[Homo sapiens]
Length = 173
Score = 42.7 bits (99), Expect = 1e-04
Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 14/147 (9%)
Query: 17 VLLFVSTIVSQW----IVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILS 72
+LL V+ W + G+ LW+ C GN + + S W + +A MILS
Sbjct: 17 ILLVVAMATDHWMQYRLSGSFAHQGLWRYCL----GNKCYLQTDSIAYW-NATRAFMILS 71
Query: 73 IIFSILSLFL---FFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEW--HLN 127
+ +I + + F T ++ R + GI + L V+ A AIYT +
Sbjct: 72 ALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGVTVSFLGRRF 131
Query: 128 SDYSYGFAYILAWVAFPLALLSGVIYV 154
D+ + ++YIL WVA + +G+ Y+
Sbjct: 132 GDWRFSWSYILGWVAVLMTFFAGIFYM 158
>gi|169163665 PREDICTED: similar to hCG1784039 [Homo sapiens]
Length = 93
Score = 41.2 bits (95), Expect = 4e-04
Identities = 17/46 (36%), Positives = 28/46 (60%)
Query: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSS 46
ML+LL + H+ LLF++TI + W VGN D+W+ C+ ++
Sbjct: 1 MLVLLTFTVAFHITSAALLFIATIDNAWWVGNEFFADVWRICTKNT 46
Score = 41.2 bits (95), Expect = 4e-04
Identities = 16/37 (43%), Positives = 26/37 (70%)
Query: 124 WHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160
++L + SYG++YILAWVAF +S ++Y+I + E
Sbjct: 57 YYLTKEGSYGYSYILAWVAFAFTFISSMMYLITEEAE 93
>gi|169163222 PREDICTED: hypothetical protein LOC391359 [Homo
sapiens]
Length = 93
Score = 41.2 bits (95), Expect = 4e-04
Identities = 17/46 (36%), Positives = 28/46 (60%)
Query: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSS 46
ML+LL + H+ LLF++TI + W VGN D+W+ C+ ++
Sbjct: 1 MLVLLTFTVAFHITSAALLFIATIDNAWWVGNEFFADVWRICTKNT 46
Score = 41.2 bits (95), Expect = 4e-04
Identities = 16/37 (43%), Positives = 26/37 (70%)
Query: 124 WHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE 160
++L + SYG++YILAWVAF +S ++Y+I + E
Sbjct: 57 YYLTKEGSYGYSYILAWVAFAFTFISSMMYLITEEAE 93
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 40.8 bits (94), Expect = 5e-04
Identities = 42/148 (28%), Positives = 64/148 (43%), Gaps = 32/148 (21%)
Query: 38 LWQNCSTSSSG----NVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQL------ 87
LW++C SSG + P LQ+V+A MI+ I+ + L + L
Sbjct: 49 LWRSCVRQSSGFTECRPYFTILGLP-AMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIG 107
Query: 88 ---------FTLTKGGRFYITGIFQILAGLCV----------MSAAAIYT-VRHPEWHLN 127
TLT G F ++G+ I AG+ V MS A +YT + +
Sbjct: 108 SMEDSAKANMTLTSGIMFIVSGLCAI-AGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQ 166
Query: 128 SDYSYGFAYILAWVAFPLALLSGVIYVI 155
+ Y++G A + WVA L L+ GV+ I
Sbjct: 167 TRYTFGAALFVGWVAGGLTLIGGVMMCI 194
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 40.4 bits (93), Expect = 7e-04
Identities = 42/148 (28%), Positives = 64/148 (43%), Gaps = 32/148 (21%)
Query: 38 LWQNCSTSSSGNV----HHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQL------ 87
LW++C SSG + P LQ+V+A MI+ I+ + L + L
Sbjct: 49 LWRSCVRESSGFTECRGYFTLLGLP-AMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIG 107
Query: 88 ---------FTLTKGGRFYITGIFQILAGLCV----------MSAAAIYT-VRHPEWHLN 127
TLT G F ++G+ I AG+ V MS A +YT + +
Sbjct: 108 SMEDSAKANMTLTSGIMFIVSGLCAI-AGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQ 166
Query: 128 SDYSYGFAYILAWVAFPLALLSGVIYVI 155
+ Y++G A + WVA L L+ GV+ I
Sbjct: 167 TRYTFGAALFVGWVAGGLTLIGGVMMCI 194
>gi|13899273 transmembrane protein 47 [Homo sapiens]
Length = 181
Score = 38.5 bits (88), Expect = 0.002
Identities = 34/158 (21%), Positives = 73/158 (46%), Gaps = 9/158 (5%)
Query: 3 LLLLSIIVLHVAVLVLLFVSTIVSQWIVGNG-HATDLWQNCSTSSSGNVHHCFSSSPNEW 61
L L+ ++ + +A L L + + W+ + + LW++C +S ++ HC S+ ++W
Sbjct: 19 LKLVGLVCIFLA-LCLDLGAVLSPAWVTADHQYYLSLWESCRKPASLDIWHCESTLSSDW 77
Query: 62 LQSVQATMILSIIFSILSLFLFFCQLFTLTKGG--RFYITGIFQILAGLCV-MSAAAIYT 118
AT+ L + + + L F L ++ G RFY + A + + + + +Y
Sbjct: 78 ---QIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLFAAVVLQVCSLVLYP 134
Query: 119 VRHPEW-HLNSDYSYGFAYILAWVAFPLALLSGVIYVI 155
++ E L + + + Y LAW A + ++Y +
Sbjct: 135 IKFIETVSLKIYHEFNWGYGLAWGATIFSFGGAILYCL 172
>gi|31377722 PERP, TP53 apoptosis effector [Homo sapiens]
Length = 193
Score = 38.1 bits (87), Expect = 0.003
Identities = 39/157 (24%), Positives = 58/157 (36%), Gaps = 31/157 (19%)
Query: 3 LLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHA--TDLWQNCSTSSSGNVHH---CFSSS 57
LLLLS I + L W+ + H + LW CS G+ + C S
Sbjct: 17 LLLLSAIAFDIIALA-------GRGWLQSSDHGQTSSLWWKCSQEGGGSGSYEEGCQSLM 69
Query: 58 PNEWLQSVQATMILSIIFSILSLFLFFCQL-------FTLTKGGRFYITGIFQILAGLCV 110
W ++ A + I ++ L F L F GG + +FQI+
Sbjct: 70 EYAWGRAAAAMLFCGFIILVICFILSFFALCGPQMLVFLRVIGGLLALAAVFQII----- 124
Query: 111 MSAAAIYTVRHPE---WHLNS--DYSYGFAYILAWVA 142
+ IY V++ + H N Y Y +AY W A
Sbjct: 125 --SLVIYPVKYTQTFTLHANPAVTYIYNWAYGFGWAA 159
>gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1
[Homo sapiens]
Length = 215
Score = 37.0 bits (84), Expect = 0.007
Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 5/96 (5%)
Query: 64 SVQATMILSIIFSILSLFL---FFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVR 120
+ +A MILS + +I + + F T ++ R + GI + L V+ A AIYT
Sbjct: 105 ATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGV 164
Query: 121 HPEW--HLNSDYSYGFAYILAWVAFPLALLSGVIYV 154
+ D+ + ++YIL WVA + +G+ Y+
Sbjct: 165 TVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYM 200
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 36.6 bits (83), Expect = 0.009
Identities = 35/140 (25%), Positives = 52/140 (37%), Gaps = 25/140 (17%)
Query: 22 STIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLF 81
S I + W+ LW NC+ G + C + A + L SI +LF
Sbjct: 36 SVITATWVYQG-----LWMNCA----GYIQACRGL--------MIAAVSLGFFGSIFALF 78
Query: 82 LFFCQLF---TLTKGGRFYITGIFQILAGLCVMSAAAIY-----TVRHPEWHLNSDYSYG 133
C K + GI IL+GLC M+ ++Y T + Y G
Sbjct: 79 GMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELG 138
Query: 134 FAYILAWVAFPLALLSGVIY 153
A + W L ++ GVI+
Sbjct: 139 AALFIGWAGASLCIIGGVIF 158
>gi|22027551 voltage-dependent calcium channel gamma-5 subunit
isoform a [Homo sapiens]
Length = 275
Score = 36.2 bits (82), Expect = 0.012
Identities = 47/193 (24%), Positives = 76/193 (39%), Gaps = 51/193 (26%)
Query: 14 AVLVLLFVSTIVSQWIVGNGHATDLW----------QNCSTSSSGNVHH-----CFSSSP 58
A+ +L V + ++G +TD W QN ST ++H CF +
Sbjct: 8 ALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCFLAGE 67
Query: 59 --------------NEWLQSVQATMILSII-----FSILSLFLFFCQLFTLTKGGRF--- 96
N L S +L +I F ++SLF F F L G
Sbjct: 68 ERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG-FILNNIGHIRPH 126
Query: 97 -----YITGIFQILAGLCVMSAAAIYTVRHPEWHLNS--------DYSYGFAYILAWVAF 143
+++GIF IL+GL ++ +Y + LN +Y YG+++ A ++F
Sbjct: 127 RTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISF 186
Query: 144 PLALLSGVIYVIL 156
L +GV+ V L
Sbjct: 187 LLTESAGVMSVYL 199
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 35.8 bits (81), Expect = 0.016
Identities = 38/146 (26%), Positives = 58/146 (39%), Gaps = 22/146 (15%)
Query: 22 STIVSQWIVGNGHATDLWQNCSTSSSG----NVHHCFSSSPNEWLQSVQATMILSIIFSI 77
S IV+ + G LW NC S+G V+ + P + LQ+ +A +I+SII +
Sbjct: 38 SNIVTSQTIWEG----LWMNCVVQSTGQMQCKVYDSLLALPQD-LQAARALVIISIIVAA 92
Query: 78 LSLFLFF-------CQLFTLTKGGRFYITGIFQILAGLCVMSAAA------IYTVRHPEW 124
L + L C K + G+ +LAGL V+ + I +P
Sbjct: 93 LGVLLSVVGGKCTNCLEDESAKAKTMIVAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLV 152
Query: 125 HLNSDYSYGFAYILAWVAFPLALLSG 150
G + + W A L LL G
Sbjct: 153 ASGQKREMGASLYVGWAASGLLLLGG 178
>gi|157951718 GSG1-like isoform 1 [Homo sapiens]
Length = 331
Score = 35.8 bits (81), Expect = 0.016
Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 23/136 (16%)
Query: 36 TDLWQNCSTSSSGNVHHCFS----SSPNE----WLQSVQATMILSII---FSILSLFLFF 84
T +W +C SG C S + +E WL V + + ++ FS++ L LF
Sbjct: 103 TGIWYSCEEELSGLGEKCRSFIDLAPASEKGVLWLSVVSEVLYILLLVVGFSLMCLELFH 162
Query: 85 CQLFTLTKGGRFY-ITGIFQILAGLCVMSAAAIYT--------VRHPEWHLNSDYSYGFA 135
+ G + +F +L+GL M A +YT + +W +S + YG++
Sbjct: 163 SS--NVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHS-WDYGWS 219
Query: 136 YILAWVAFPLALLSGV 151
+ LAW +F + + V
Sbjct: 220 FCLAWGSFTCCMAASV 235
>gi|93588657 claudin domain containing 1 protein isoform d [Homo
sapiens]
Length = 158
Score = 35.4 bits (80), Expect = 0.021
Identities = 18/62 (29%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 99 TGIFQILAGLCVMSAAAIYT----VRHPEWHLNSDYS--YGFAYILAWVAFPLALLSGVI 152
TGI +LAGLC + + + Y + H + L + S +G+++ LA V+ PL ++ +
Sbjct: 78 TGILHLLAGLCTLGSVSCYVAGIELLHQKLELPDNVSGEFGWSFCLACVSAPLQFMASAL 137
Query: 153 YV 154
++
Sbjct: 138 FI 139
>gi|93588650 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 35.4 bits (80), Expect = 0.021
Identities = 18/62 (29%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 99 TGIFQILAGLCVMSAAAIYT----VRHPEWHLNSDYS--YGFAYILAWVAFPLALLSGVI 152
TGI +LAGLC + + + Y + H + L + S +G+++ LA V+ PL ++ +
Sbjct: 173 TGILHLLAGLCTLGSVSCYVAGIELLHQKLELPDNVSGEFGWSFCLACVSAPLQFMASAL 232
Query: 153 YV 154
++
Sbjct: 233 FI 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.331 0.140 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,345,118
Number of Sequences: 37866
Number of extensions: 190582
Number of successful extensions: 783
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 736
Number of HSP's gapped (non-prelim): 75
length of query: 160
length of database: 18,247,518
effective HSP length: 94
effective length of query: 66
effective length of database: 14,688,114
effective search space: 969415524
effective search space used: 969415524
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.