Guide to the Human Genome
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Search of human proteins with 24430132

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24430132 WW domain binding protein 2 [Homo sapiens]
         (261 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24430132 WW domain binding protein 2 [Homo sapiens]                560   e-160
gi|224593260 WBP2 N-terminal like [Homo sapiens]                      140   9e-34
gi|59806357 submaxillary gland androgen regulated protein 3 homo...    59   4e-09
gi|157168329 formin 1 [Homo sapiens]                                   58   7e-09
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    58   7e-09
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         58   1e-08
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    57   2e-08
gi|160707881 formin 2 [Homo sapiens]                                   55   5e-08
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               55   6e-08
gi|25470890 DAZ associated protein 1 isoform a [Homo sapiens]          55   8e-08
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    55   8e-08
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 54   1e-07
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 54   1e-07
gi|210032580 SET domain containing 1B [Homo sapiens]                   54   1e-07
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    54   1e-07
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     54   2e-07
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     54   2e-07
gi|33356148 formin-like 1 [Homo sapiens]                               54   2e-07
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             53   2e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    53   3e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    53   3e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   4e-07
gi|146134388 YLP motif containing 1 [Homo sapiens]                     52   4e-07
gi|41281808 harmonin isoform b3 [Homo sapiens]                         52   5e-07
gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens]          52   5e-07
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    52   7e-07
gi|11386183 WAS protein family, member 2 [Homo sapiens]                52   7e-07
gi|56549694 enabled homolog isoform a [Homo sapiens]                   51   9e-07
gi|39930375 enabled homolog isoform b [Homo sapiens]                   51   9e-07
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    51   1e-06

>gi|24430132 WW domain binding protein 2 [Homo sapiens]
          Length = 261

 Score =  560 bits (1442), Expect = e-160
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFL 60
           MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFL
Sbjct: 1   MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFL 60

Query: 61  SKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAGGAI 120
           SKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAGGAI
Sbjct: 61  SKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAGGAI 120

Query: 121 EFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY 180
           EFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY
Sbjct: 121 EFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY 180

Query: 181 PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV 240
           PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV
Sbjct: 181 PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV 240

Query: 241 YMPTSQPPPPPYYPPEDKKTQ 261
           YMPTSQPPPPPYYPPEDKKTQ
Sbjct: 241 YMPTSQPPPPPYYPPEDKKTQ 261


>gi|224593260 WBP2 N-terminal like [Homo sapiens]
          Length = 309

 Score =  140 bits (354), Expect = 9e-34
 Identities = 92/229 (40%), Positives = 118/229 (51%), Gaps = 34/229 (14%)

Query: 1   MALNKNHSEGG-GVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIF 59
           MA+N++H+E   G ++ N ES+L    +VEL+F         F G K GT++LT YRVIF
Sbjct: 1   MAVNQSHTENRRGALIPNGESLLKRSPNVELSFPQRSEGSNVFSGRKTGTLFLTSYRVIF 60

Query: 60  LSKGK--DAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAG 117
           ++     D M SFMMPF LM +  ++QPVF AN+IKGT++A   GGWEG A++KL F  G
Sbjct: 61  ITSCSISDPMLSFMMPFDLMTNLTVEQPVFAANFIKGTIQAAPYGGWEGQATFKLVFRNG 120

Query: 118 GAIEFGQRMLQVASQASRG-----------------EVPSGAYGYSYMPSGAYVYPPPVA 160
            AIEF Q M++ AS A+RG                     G      MP    VY  P A
Sbjct: 121 DAIEFAQLMVKAASAAARGFPLRTLNDWFSSMGIYVITGEGNMCTPQMPCSVIVYGAPPA 180

Query: 161 NGMYPCPPGYPYPPP-----------PPEFYPGPPMMDGA--MGYVQPP 196
               P PPGY  PP            PP  Y   P+  GA  +GY  PP
Sbjct: 181 GYGAP-PPGYGAPPAGYGAQPVGNEGPPVGYRASPVRYGAPPLGYGAPP 228


>gi|59806357 submaxillary gland androgen regulated protein 3 homolog
           A precursor [Homo sapiens]
          Length = 134

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 37/99 (37%), Positives = 43/99 (43%), Gaps = 16/99 (16%)

Query: 165 PCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPP-PPPY-PGPMEPPVSGP-------DVPS 215
           P PPG   PPPPP F  G        G+V PP PPPY PG   PP+S P         P 
Sbjct: 29  PYPPGPLAPPPPPCFPFGT-------GFVPPPHPPPYGPGRFPPPLSPPYGPGRIPPSPP 81

Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
            P    +    +    Y PG P     P   PP PP++P
Sbjct: 82  PPYGPGRIQSHSLPPPYGPGYPQPPSQPRPYPPGPPFFP 120



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 33/99 (33%), Positives = 41/99 (41%), Gaps = 20/99 (20%)

Query: 139 PSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPY------PPPPPEFYPG--------PP 184
           P   +G  ++P     +PPP   G +P P   PY      P PPP + PG        PP
Sbjct: 41  PCFPFGTGFVPPP---HPPPYGPGRFPPPLSPPYGPGRIPPSPPPPYGPGRIQSHSLPPP 97

Query: 185 MMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKA 223
                 GY QPP  P P P  PP    + P+ PA    A
Sbjct: 98  Y---GPGYPQPPSQPRPYPPGPPFFPVNSPTDPALPTPA 133


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 34/91 (37%), Positives = 37/91 (40%), Gaps = 10/91 (10%)

Query: 167 PPGYPYPPPPP------EFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAE 220
           PP    PPPPP         P PPM   + G   PPPPP P P+ PP S    P  P   
Sbjct: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPP 706

Query: 221 AKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251
              + A      NPG P     P    PPPP
Sbjct: 707 LPNSPAPP----NPGGPPPAPPPPGLAPPPP 733



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 31/83 (37%), Positives = 34/83 (40%), Gaps = 15/83 (18%)

Query: 138 VPSGAYGYSYMP------SGAYVYPPPVANGMYPCPP--GYPYPPPPPEF--YPGPPMMD 187
           +PSG    S  P      +G  + PPP      P P   G P PPPPP     P PP   
Sbjct: 658 LPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPG 717

Query: 188 GAMGYVQPPPPPYPGPMEPPVSG 210
           G      PP PP PG   PP  G
Sbjct: 718 GP-----PPAPPPPGLAPPPPPG 735



 Score = 31.6 bits (70), Expect = 0.73
 Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 7/58 (12%)

Query: 156 PPPVANGMYPCPPGYP--YPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG-----PMEP 206
           PPP+ N   P  PG P   PPPP    P PP +   +G      P  P      PM+P
Sbjct: 704 PPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 41/123 (33%), Positives = 46/123 (37%), Gaps = 12/123 (9%)

Query: 139 PSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQP-PP 197
           P G  G    P    V PPP+A      PP     PPPP  +PG P     +G + P PP
Sbjct: 243 PPGPPGPPGPPPPGQVLPPPLAG-----PPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP 297

Query: 198 PPYPG-----PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPY 252
           PP PG        PP  GP  P  P                P  PH    P   PPP P+
Sbjct: 298 PPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP-PPHLPGPPPGAPPPAPH 356

Query: 253 YPP 255
             P
Sbjct: 357 VNP 359



 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 50/143 (34%), Positives = 63/143 (44%), Gaps = 26/143 (18%)

Query: 129 VASQASRGEVPSGAYGYSYMPSGAYVYPP--PVANGMYPCPPGY-PYP-PPPPEFYPGPP 184
           +A   +RG+ P     +   P G    PP  P+  G  P  PGY P P PPPP+  P PP
Sbjct: 263 LAGPPNRGDRPPPPVLFPGQPFGQ---PPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPP 319

Query: 185 MMDGAMGYVQPPPPPYPGPMEPPVS---GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVY 241
                     P PP  PGP+ PP++    P +P  P      A     A++ P  P N  
Sbjct: 320 --------PGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPP--PTNSG 369

Query: 242 MPTSQ----PPPPPY--YPPEDK 258
           MPTS     PP  PY   PP D+
Sbjct: 370 MPTSDSRGPPPTDPYGRPPPYDR 392



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 46/135 (34%), Positives = 52/135 (38%), Gaps = 21/135 (15%)

Query: 133 ASRGEVPSGAYGYSYMPS---GAYVYPPPVANGMYPCP-PGYPYPPPPPEFYPGPPMMDG 188
           +SR   P G  G    P    G   +P P   G  P P P    PP PP   PGPP    
Sbjct: 192 SSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPP---- 247

Query: 189 AMGYVQPPPPPYPGP-MEPPVSGP----DVPSTPAA-EAKAAEAAASAYYNPGNPHNV-- 240
                 PP PP PG  + PP++GP    D P  P     +           PG P  V  
Sbjct: 248 -----GPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG 302

Query: 241 YMPTSQPPPPPYYPP 255
           Y P   PPPP   PP
Sbjct: 303 YGPPPGPPPPQQGPP 317



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 30/81 (37%), Positives = 34/81 (41%), Gaps = 14/81 (17%)

Query: 156 PPPVANGMYPCPPGYPYPPPP--PEFYPGPPM--MDGAMGYVQPP------PPPYP-GPM 204
           PPP   G    PPG P P P   P F+P P    M  +     PP      PPPY  G  
Sbjct: 339 PPPHLPGP---PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDY 395

Query: 205 EPPVSGPDVPSTPAAEAKAAE 225
            PP    D   TP +EA+  E
Sbjct: 396 GPPGREMDTARTPLSEAEFEE 416


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 41/143 (28%), Positives = 56/143 (39%), Gaps = 10/143 (6%)

Query: 113 TFTAGGAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPY 172
           ++ +G   +  Q M++     S G +P      +++P   +VYPP         PP  P 
Sbjct: 437 SYMSGEGYQSLQSMMKTEGP-SYGALPPAYGPPAHLPYHPHVYPPN--------PPPPPV 487

Query: 173 PPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYY 232
           PPPP  F P P +     GY  PPP   P    PP   P   + P           ++Y 
Sbjct: 488 PPPPASF-PPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYP 546

Query: 233 NPGNPHNVYMPTSQPPPPPYYPP 255
            P  P     P   P PPP  PP
Sbjct: 547 PPAVPPGGQPPVPPPIPPPGMPP 569



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 31/75 (41%), Positives = 35/75 (46%), Gaps = 17/75 (22%)

Query: 149 PSGAYVYPPPVANGMYPCPPGY--------PYPPP----PPEFYPGPPMMDGAMGYVQPP 196
           P+  Y  PPP  N  +P PP          P+PPP    PP  YP P +  G     QPP
Sbjct: 502 PTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGG----QPP 557

Query: 197 -PPPYPGPMEPPVSG 210
            PPP P P  PPV G
Sbjct: 558 VPPPIPPPGMPPVGG 572



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 31/113 (27%), Positives = 42/113 (37%), Gaps = 14/113 (12%)

Query: 157 PPVANGMYPCPPGYPYPPPPP-------EFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVS 209
           P +     P PP +P P   P       E  P  P+    +  VQ PPP +P P+  P  
Sbjct: 356 PKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPP 415

Query: 210 GPDVPSTPAAEAKAAEAAASAYYNPGNPH---NVYMPTSQPP----PPPYYPP 255
            P  P  P   +     + ++ Y  G  +      M T  P     PP Y PP
Sbjct: 416 LPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPP 468



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 39/130 (30%), Positives = 45/130 (34%), Gaps = 35/130 (26%)

Query: 156 PPPVANGMYPCPPGYPY--PPPPPEFY-------------------------PGPPMMDG 188
           PPP        PP  P+  PPPPP  Y                          GP    G
Sbjct: 402 PPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSY--G 459

Query: 189 AMGYVQPPP---PPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTS 245
           A+     PP   P +P    P    P VP  PA+    A    +  Y P  P   Y P +
Sbjct: 460 ALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPP--PPPTYNP-N 516

Query: 246 QPPPPPYYPP 255
            PPPPP  PP
Sbjct: 517 FPPPPPRLPP 526



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 24/66 (36%), Positives = 29/66 (43%), Gaps = 8/66 (12%)

Query: 194 QPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYY 253
           Q P  P P P  P      V  +P  E KAAE        P  P    + T+ PP PP +
Sbjct: 318 QQPKKPSPQPSSPRQVKRAVVVSPKEENKAAE--------PPPPKIPKIETTHPPLPPAH 369

Query: 254 PPEDKK 259
           PP D+K
Sbjct: 370 PPPDRK 375



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 1/81 (1%)

Query: 181 PGPPMMDGAMGYVQPPPPPYPGP-MEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHN 239
           P PP +        P PP +P P  +PP++     + P     A +        P +P  
Sbjct: 350 PPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAP 409

Query: 240 VYMPTSQPPPPPYYPPEDKKT 260
           V+ P   P  PP  PP    T
Sbjct: 410 VHQPPPLPHRPPPPPPSSYMT 430


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 30/82 (36%), Positives = 37/82 (45%), Gaps = 1/82 (1%)

Query: 156 PPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215
           PPP+ +   P PP   +  PPP+F P PP     +   + PPPP P P   P   PD   
Sbjct: 560 PPPLDDPELPPPPP-DFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSAR 618

Query: 216 TPAAEAKAAEAAASAYYNPGNP 237
            P A AK          NPG+P
Sbjct: 619 PPPAVAKRPPVPPKRQENPGHP 640



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 31/114 (27%), Positives = 38/114 (33%), Gaps = 35/114 (30%)

Query: 157 PPVANGMYPCPPGYPY------PPPPP-------EFYPGPPMMDGAMGYVQPPPPPY--- 200
           P + N   P  P  P+      PPPPP          P  P+     G    P PP    
Sbjct: 495 PALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFL 554

Query: 201 -PGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYY 253
            P P  PP+  P++P  P             +  P        P   PPPPP Y
Sbjct: 555 PPPPPPPPLDDPELPPPPPD-----------FMEPP-------PDFVPPPPPSY 590



 Score = 28.9 bits (63), Expect = 4.7
 Identities = 23/76 (30%), Positives = 25/76 (32%), Gaps = 11/76 (14%)

Query: 181 PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV 240
           P  P    A     PPPPP            D   +PA   KA          P  P + 
Sbjct: 503 PAVPRAPHAPKSSLPPPPPVR-------RSSDTSGSPATPLKAKGTGGGGL--PAPPDDF 553

Query: 241 YMPTSQPPPPPYYPPE 256
             P   PPPPP   PE
Sbjct: 554 LPPP--PPPPPLDDPE 567


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 13/116 (11%)

Query: 148  MPSGAYVYPPPVANGMYPCPPGYP---YPPPPP---EFYPGPPMMDGAMGYVQPPPPPYP 201
            +P      PPP+     P PP  P    PPPPP      P PP + GA     PPPPP P
Sbjct: 970  LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA---GIPPPPPLP 1026

Query: 202  G---PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
            G   P  PP+ G  +P  P     A           G P    +P +  PPPP  P
Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1081



 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 13/116 (11%)

Query: 148  MPSGAYVYPPPVANGMYPCPPGYP---YPPPPP---EFYPGPPMMDGAMGYVQPPPPPYP 201
            +P      PPP+     P PP  P    PPPPP      P PP + GA     PPPPP P
Sbjct: 981  LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA---GIPPPPPLP 1037

Query: 202  G---PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
            G   P  PP+ G  +P  P     A           G P    +P +  PPPP  P
Sbjct: 1038 GAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1092



 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 13/116 (11%)

Query: 148  MPSGAYVYPPPVANGMYPCPPGYP---YPPPPP---EFYPGPPMMDGAMGYVQPPPPPYP 201
            +P      PPP+     P PP  P    PPPPP      P PP + GA     PPPPP P
Sbjct: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA---GIPPPPPLP 1092

Query: 202  G---PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
            G   P  PP+ G  +P  P     A           G P    +P +  PPPP  P
Sbjct: 1093 GAGIPPPPPLPGVGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1147



 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 38/113 (33%), Positives = 44/113 (38%), Gaps = 7/113 (6%)

Query: 148  MPSGAYVYPPPVANGMYPCPPGYP---YPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG-- 202
            +P      PPP+     P PP  P    PPPPP    G P      G   PPPPP PG  
Sbjct: 1058 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG 1117

Query: 203  -PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
             P  PP+ G  +P  P     A           G P    +P +  PPPP  P
Sbjct: 1118 IPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP 1169



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 8/111 (7%)

Query: 151  GAYVYP-PPVANGMYPCPPGYP---YPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG---P 203
            GA + P PP+     P PP  P    PPPPP    G P+     G   PPPPP PG   P
Sbjct: 928  GAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIP 987

Query: 204  MEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
              PP+ G  +P  P     A           G P    +P +  PPPP  P
Sbjct: 988  PPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 39/116 (33%), Positives = 46/116 (39%), Gaps = 24/116 (20%)

Query: 148  MPSGAYVYPPPVANGMYPCPPGYP---YPPPPP---EFYPGPPMMDGAMGYVQPPPPPYP 201
            +P      PPP+     P PP  P    PPPPP      P PP + GA     PPPPP P
Sbjct: 1113 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA---GIPPPPPLP 1169

Query: 202  G---PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
            G   P  PP+ G  +P  P                 G P    +P +  PPPP  P
Sbjct: 1170 GAGIPPPPPLPGVGIPPPPPLP------------GVGIPPPPPLPGAGIPPPPPLP 1213



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 36/102 (35%), Positives = 40/102 (39%), Gaps = 14/102 (13%)

Query: 156  PPPVANGMYPCPPGYP---YPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG---PMEPPVS 209
            PPP+     P PP  P    PPPPP    G P      G   PPPPP PG   P  PP+ 
Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1213

Query: 210  GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251
            G  +P  PA                G P    +P S PP  P
Sbjct: 1214 GMGIPPAPAPPLPPP--------GTGIPPPPLLPVSGPPLLP 1247



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 9/73 (12%)

Query: 148  MPSGAYVYPPPVANGMYPCPPGYP---YPPPPP---EFYPGPPMMDGAMGYVQPPPPPYP 201
            +P      PPP+     P PP  P    PPPPP      P PP + GA     PPPPP P
Sbjct: 1157 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGA---GIPPPPPLP 1213

Query: 202  GPMEPPVSGPDVP 214
            G   PP   P +P
Sbjct: 1214 GMGIPPAPAPPLP 1226



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 6/108 (5%)

Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG-PMEP 206
           +PS A   PPP+  G    PP  P PP P    P PP + GA G +  PP P  G P  P
Sbjct: 891 LPSTAIPQPPPL-QGTEMLPP--PPPPLPGAGIPPPPPLPGA-GILPLPPLPGAGIPPPP 946

Query: 207 PVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
           P+ G  +P  P     A           G P    +P +  PPPP  P
Sbjct: 947 PLPGAAIPPPPPLPG-AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLP 993



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 40/154 (25%), Positives = 51/154 (33%), Gaps = 49/154 (31%)

Query: 146 SYMPSGAYVYPPPVANGMYPCPPGYPYPPPP----PEFY-----------------PGPP 184
           S+ P+ +   PPP  + ++    G P   PP     EF                  P PP
Sbjct: 800 SHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP 859

Query: 185 MMD--------GAMGYVQPPPPPYPG-----------PMEPPVSG-----PDVPSTPAAE 220
            +           +G V PPPPP PG           P  PP+ G     P  P  P A 
Sbjct: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAG 919

Query: 221 AKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
                    A   P  P    +P +  PPPP  P
Sbjct: 920 IPPPPPLPGAGILPLPP----LPGAGIPPPPPLP 949



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 25/71 (35%), Positives = 27/71 (38%), Gaps = 9/71 (12%)

Query: 156  PPPVANGMYPCPPGYP---YPPPPP------EFYPGPPMMDGAMGYVQPPPPPYPGPMEP 206
            PPP+     P PP  P    PPPPP         P PP+     G   PP  P  GP   
Sbjct: 1187 PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLL 1246

Query: 207  PVSGPDVPSTP 217
            P  G     TP
Sbjct: 1247 PQVGSSTLPTP 1257



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 9/66 (13%)

Query: 151  GAYVYPPPVANGM-YPCPPGYPYPP-----PPPEFYP--GPPMMDGAMGYVQPPPPPYPG 202
            GA + PPP   GM  P  P  P PP     PPP   P  GPP++   +G    P P   G
Sbjct: 1203 GAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLP-QVGSSTLPTPQVCG 1261

Query: 203  PMEPPV 208
             + PP+
Sbjct: 1262 FLPPPL 1267


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 39/109 (35%), Positives = 44/109 (40%), Gaps = 12/109 (11%)

Query: 149 PSGAYVYPPPVANGMYPCPP-GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYP-GPMEP 206
           P G    PPP+ NG+ P PP     PPPPP   P PPM         PP  P P GP  P
Sbjct: 227 PPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPM---------PPTGPAPSGPPGP 277

Query: 207 PVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
           P   P  P      A      AS  + P    +   P   PP P  +PP
Sbjct: 278 PQLPPPAPGVHPP-APVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPP 325



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 42/132 (31%), Positives = 54/132 (40%), Gaps = 15/132 (11%)

Query: 136 GEVPSGAYGYSYMPSGAY-VYPP-----PVANGMYPCPPGYPYPPPPPEFYPGPPMMDGA 189
           G  PSG  G   +P  A  V+PP     P A+G++P  PG    PP P  +P  P +   
Sbjct: 268 GPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVH--PPAPGVHPPAPGVHPP 325

Query: 190 MGYVQPPP----PPYPGPMEPPVSGPDVPSTPA-AEAKAAEAAASAYYNPGNPH-NVYMP 243
              V PP     PP PG + PP  G   P+      A       SA  +P  P  +   P
Sbjct: 326 TSGVHPPAPGVHPPAPG-VHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAP 384

Query: 244 TSQPPPPPYYPP 255
              P  P  +PP
Sbjct: 385 AVHPQAPGVHPP 396



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 34/108 (31%), Positives = 41/108 (37%), Gaps = 15/108 (13%)

Query: 157 PPVANGMYPCPPGYPYPPPPPEFY---PGPPMMDGAMGYVQPPPPP--YPGPMEPPV--- 208
           PP    +   PPG   PPPP       P PP+ +       PPPPP   P P  PP    
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPL-MNGLPPRPPLPESL-----PPPPPGGLPLPPMPPTGPA 270

Query: 209 -SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
            SGP  P      A      A   + P +  +   P   PP P  +PP
Sbjct: 271 PSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPP 318



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 40/121 (33%), Positives = 49/121 (40%), Gaps = 24/121 (19%)

Query: 149 PSGAYVYPP-----PVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQP------PP 197
           P    V+PP     P A G++P  PG  +PPP    +P  P +  A   V P      PP
Sbjct: 338 PPAPGVHPPAPGVHPPAPGVHPPAPGV-HPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPP 396

Query: 198 PPYPGPMEPPV--SGPDV-PSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
            P   P  P V    P V PS P    +          +P NP  V+ PT  P PP   P
Sbjct: 397 APGMHPQAPGVHPQPPGVHPSAPGVHPQPPGV------HPSNP-GVHPPT--PMPPMLRP 447

Query: 255 P 255
           P
Sbjct: 448 P 448



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 20/113 (17%)

Query: 149 PSGAYVYPP-----PVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGP 203
           P    V+PP     P A G++P  PG    PP P  +P  P +           PP PG 
Sbjct: 317 PPAPGVHPPTSGVHPPAPGVHPPAPGVH--PPAPGVHPPAPGVH----------PPAPGV 364

Query: 204 MEPPVSG--PDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
             PP +G  P  P    A A A    A   + P    +   P   P PP  +P
Sbjct: 365 HPPPSAGVHPQAPGVHPA-APAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHP 416



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 36/120 (30%), Positives = 42/120 (35%), Gaps = 20/120 (16%)

Query: 149 PSGAYVYPPPVANGMYPC-PPGYP---------YPPPPPEFYPGPPMMDGAMGYVQPPP- 197
           P G    PP    G  P  PPG P         +PP P    P   +   A G   P P 
Sbjct: 255 PPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPG 314

Query: 198 --PPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
             PP PG + PP SG   P      A      A   + P    +   P   PP P  +PP
Sbjct: 315 VHPPAPG-VHPPTSGVHPP------APGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPP 367



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 40/117 (34%), Positives = 46/117 (39%), Gaps = 27/117 (23%)

Query: 149 PSGAYVYPPPVANGMYPCPPG-YP-----YPPPPPEFYPGPPMMDGAMGYVQPPP---PP 199
           P    V+PPP A G++P  PG +P     +P  P    P P M   A G    PP   P 
Sbjct: 359 PPAPGVHPPPSA-GVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPS 417

Query: 200 YPG--PMEPPV--SGPDV-PSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251
            PG  P  P V  S P V P TP          +     PGN          PPPPP
Sbjct: 418 APGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSE---GPGN---------IPPPPP 462


>gi|25470890 DAZ associated protein 1 isoform a [Homo sapiens]
          Length = 378

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 46/161 (28%), Positives = 61/161 (37%), Gaps = 30/161 (18%)

Query: 118 GAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVY---------PPPVANGMYPCPP 168
           GA ++G R++  A+    G+ P   +   Y P G +V          PPP   G  P PP
Sbjct: 202 GASQWGSRVVPNAANGWAGQPPP-TWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPP 260

Query: 169 ------------GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPP----YPGPMEPPVSGPD 212
                       G+P P   P+ Y  PP    + GY  PPPPP     PG   PP +   
Sbjct: 261 PFTSYIVSTPPGGFPPPQGFPQGYGAPPQF--SFGYGPPPPPPDQFAPPGVPPPPATPGA 318

Query: 213 VPST--PAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251
            P    P     A + +      P  P+  Y   S  P PP
Sbjct: 319 APLAFPPPPSQAAPDMSKPPTAQPDFPYGQYGLGSYSPAPP 359


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 40/118 (33%), Positives = 49/118 (41%), Gaps = 23/118 (19%)

Query: 157  PPVANGMYPCPPGYPYPP--------PPP---EFYPGP-----PMMDGAMGYVQPPPPPY 200
            PP A G+ P    YPY P        PPP   + YPGP     P   GA+ +  P PP  
Sbjct: 985  PPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQ- 1043

Query: 201  PGPMEPPVSGPDVPST----PAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
              P  PP++    PST    P A        +SA  +  +PH V  P   P P P  P
Sbjct: 1044 --PPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPP 1099



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 37/141 (26%), Positives = 47/141 (33%), Gaps = 32/141 (22%)

Query: 139  PSGAYGYSYMPSGAYVYPPPVANGMYPCPP---------GYPYPPPPPEFYPGPPMMDG- 188
            P   Y Y+  P      PPP+   +YP P            P+P P P   P PP+  G 
Sbjct: 994  PQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGP 1053

Query: 189  --------------------AMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAA--EA 226
                                + G   P P   P P   P  GP  P  PAAE        
Sbjct: 1054 APSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRG 1113

Query: 227  AASAYYNPGNPHNVYMPTSQP 247
            AA+A     +P + +  T  P
Sbjct: 1114 AAAADLLSSSPESQHGGTQSP 1134



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 35/134 (26%), Positives = 52/134 (38%), Gaps = 23/134 (17%)

Query: 138  VPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGY----- 192
            +P+  +  S +P+G   +P P      P P  +P P P   F P PP     + +     
Sbjct: 932  IPAQHHFSSGIPAG---FPAPRIG---PQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFP 985

Query: 193  -----VQPPPPPYPGPMEPPVSGPDVPST-------PAAEAKAAEAAASAYYNPGNPHNV 240
                 + PP  PYP   +P V G   P         PA +   A + A  + +PG P   
Sbjct: 986  PQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPP 1045

Query: 241  YMPTSQPPPPPYYP 254
            + P +  P P   P
Sbjct: 1046 HPPLAYGPAPSTRP 1059



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 36/127 (28%), Positives = 46/127 (36%), Gaps = 12/127 (9%)

Query: 136 GEVPSGAYG---YSYMPSGAYVYPPPVANG--MYPCPPGYPYPPPPPEFYPGPPMMDGAM 190
           G +P G Y        P     +  PVA G  +YP P   P     P   P   ++    
Sbjct: 789 GPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPY 848

Query: 191 GYVQPPPPPYPGPMEPP--VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQP- 247
             V P PP    P  PP   SGP++    A   + A     +   P   H    P   P 
Sbjct: 849 VGVGPAPPVAGLPSAPPPQFSGPEL----AMAVRPATTTVDSIQAPIPSHTAPRPNPTPA 904

Query: 248 PPPPYYP 254
           PPPP +P
Sbjct: 905 PPPPCFP 911



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 29/112 (25%), Positives = 40/112 (35%), Gaps = 18/112 (16%)

Query: 162 GMYPCPPGYPYPPPPPEFYPGPPM----------MDGAMGYV------QPPPPPYPGPME 205
           G+ P PP    P  PP  + GP +          +D     +      +P P P P P  
Sbjct: 850 GVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPC 909

Query: 206 PPVSGPDVPSTPAAEAKAAE--AAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
            PV  P    TP      A+    A  +++ G P     P   P P P+  P
Sbjct: 910 FPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQP 961



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 28/105 (26%), Positives = 36/105 (34%), Gaps = 15/105 (14%)

Query: 167 PPGYPYPPPPPEFYPGPPMMDGAM------GYVQPPPPPYPGPMEPPVS-GPDVPSTPA- 218
           P  +P  P P    PGP  + G +      G  Q   P  PGP   PV+ GP +   PA 
Sbjct: 768 PLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAY 827

Query: 219 -------AEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPE 256
                    +       S+ Y    P          PPP +  PE
Sbjct: 828 TPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPE 872


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 49/175 (28%), Positives = 62/175 (35%), Gaps = 60/175 (34%)

Query: 141 GAYGYSYMPSGA---YVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGA-------- 189
           G +   + P+G    ++ PPP      P PPG+  PPP  ++    P+  G         
Sbjct: 409 GGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468

Query: 190 ------MGYVQPPPPPYPGPMEPPVSGPDVP----------------------------- 214
                 MG + PPPPP  G   PP SGP  P                             
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528

Query: 215 -----------STPAAEAKAAEAAAS--AYYNPGNPHNVYMPTS-QPPPPPYYPP 255
                      S P  + + A AAAS  A    GNP  V +P   QPP PP  PP
Sbjct: 529 TTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPP 583



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 24/53 (45%), Positives = 24/53 (45%), Gaps = 12/53 (22%)

Query: 163 MYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215
           M P PPG   PP PP   P PP          PPPP   G M PP  G D PS
Sbjct: 566 MVPLPPGV-QPPLPPGAPPPPP----------PPPPGSAGMMIPP-RGGDGPS 606



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 5/96 (5%)

Query: 158 PVANGMYPCPPGYPYPPPP--PEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215
           P+A+   P  P    PPP         PP M+      +P    + G    P  GP    
Sbjct: 339 PLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFP 398

Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251
            P              +NP  P   +M   QPPPPP
Sbjct: 399 HPLPSLTGGHGGHPMQHNPNGPPPPWM---QPPPPP 431


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 49/175 (28%), Positives = 62/175 (35%), Gaps = 60/175 (34%)

Query: 141 GAYGYSYMPSGA---YVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGA-------- 189
           G +   + P+G    ++ PPP      P PPG+  PPP  ++    P+  G         
Sbjct: 409 GGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468

Query: 190 ------MGYVQPPPPPYPGPMEPPVSGPDVP----------------------------- 214
                 MG + PPPPP  G   PP SGP  P                             
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528

Query: 215 -----------STPAAEAKAAEAAAS--AYYNPGNPHNVYMPTS-QPPPPPYYPP 255
                      S P  + + A AAAS  A    GNP  V +P   QPP PP  PP
Sbjct: 529 TTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPP 583



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 46/152 (30%), Positives = 59/152 (38%), Gaps = 43/152 (28%)

Query: 104 WEGSASYKLTFTAGGAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGM 163
           W+ + +   T    G+I   Q+  Q A+ AS G  P      + +P    V PP      
Sbjct: 525 WQQNTTTTTTSAGTGSIPPWQQQ-QAAAAASPG-APQMQGNPTMVPLPPGVQPP------ 576

Query: 164 YPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEP----PVSGPDVPSTPAA 219
              PPG P PPPPP     PP   G+ G +  PPPP P PM+P     + G  V   P  
Sbjct: 577 --LPPGAPPPPPPP-----PP---GSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPP- 625

Query: 220 EAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251
                                 MP + PPPPP
Sbjct: 626 --------------------FGMPPAPPPPPP 637



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 5/96 (5%)

Query: 158 PVANGMYPCPPGYPYPPPP--PEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215
           P+A+   P  P    PPP         PP M+      +P    + G    P  GP    
Sbjct: 339 PLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFP 398

Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251
            P              +NP  P   +M   QPPPPP
Sbjct: 399 HPLPSLTGGHGGHPMQHNPNGPPPPWM---QPPPPP 431


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 37/106 (34%), Positives = 41/106 (38%), Gaps = 15/106 (14%)

Query: 149 PSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPV 208
           P  A V  P V     P PP   +PP PP   P PP     M    PPPPP P P  P V
Sbjct: 664 PGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAV 723

Query: 209 SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
           + P  P  PA               PG P    +P   P PP  +P
Sbjct: 724 TVPP-PPLPAP--------------PGVPPPPILPPLPPFPPGLFP 754



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 31/108 (28%), Positives = 38/108 (35%), Gaps = 18/108 (16%)

Query: 157  PPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYP-------------GP 203
            PP+   M P P   P PPP P   P PP          P  PP P             G 
Sbjct: 1270 PPM---MLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGS 1326

Query: 204  MEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251
            +    S   VP+TP  E     +  S+  +  +P     P S P P P
Sbjct: 1327 LAKSQSTETVPATPGGEPPL--SGGSSGLSLSSPQVPGSPFSYPAPSP 1372



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 33/124 (26%), Positives = 47/124 (37%), Gaps = 11/124 (8%)

Query: 130 ASQASRG--EVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMD 187
           A+ A RG  ++P GA G +   SG      P  +  +       + PPP +  P P    
Sbjct: 342 ATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFA------HTPPPAQATPAPGFKS 395

Query: 188 GAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQP 247
               Y Q P   +P P E P +     +  + E + A A       P  P     P + P
Sbjct: 396 AFSPY-QTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPP--LPPAEPLAKEKPGTPP 452

Query: 248 PPPP 251
            PPP
Sbjct: 453 GPPP 456



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 18/38 (47%), Positives = 19/38 (50%), Gaps = 14/38 (36%)

Query: 169  GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEP 206
            G P PPPP      PP         QPPPPP P P+EP
Sbjct: 1535 GIPAPPPPL-----PP---------QPPPPPPPPPVEP 1558



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 34/113 (30%), Positives = 40/113 (35%), Gaps = 26/113 (23%)

Query: 165  PCPPGYPYP----PPPPEFYPG-----PPMMDGAMGYVQPPPPP---------YPGPMEP 206
            P PP  P P    PPP +  PG     PP M    G +  PP            PG  + 
Sbjct: 1456 PLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQT 1515

Query: 207  PVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKK 259
            PV     PST        +   +    P  P    +P   PPPPP  P E  K
Sbjct: 1516 PV----FPSTHDPRTVTLDFRNAGIPAPPPP----LPPQPPPPPPPPPVEPTK 1560



 Score = 32.3 bits (72), Expect = 0.43
 Identities = 29/100 (29%), Positives = 37/100 (37%), Gaps = 19/100 (19%)

Query: 173 PPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPV---------SGPDVPST----PAA 219
           P PPPE  PGPP   G +           G   P           SG D+  +    P+A
Sbjct: 592 PRPPPE--PGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSA 649

Query: 220 EAKAAEAAASAYYNPGNPH----NVYMPTSQPPPPPYYPP 255
              +A+        PG       +V  PT   PPPP +PP
Sbjct: 650 PITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPP 689



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 31/108 (28%), Positives = 36/108 (33%), Gaps = 33/108 (30%)

Query: 155 YPPPVANGMYPCPPGYPYP---------------PPPPEFYPGPPMMDGAMGYVQPPPPP 199
           Y  PVA+  +P PP  P                 P PP   P  P+     G    PPPP
Sbjct: 400 YQTPVAH--FPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPP 457

Query: 200 YPGPME---PPVSG-----PDVPSTPAAEAKAAEAAASAYYNPGNPHN 239
               ME    P  G      D P TP  E+  A         P  PH+
Sbjct: 458 DTNSMELGGRPTFGWSPEPCDSPGTPTLESSPA--------GPEKPHD 497



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 16/42 (38%), Positives = 18/42 (42%), Gaps = 3/42 (7%)

Query: 156 PPPVANGMYPCPPGYPYPP---PPPEFYPGPPMMDGAMGYVQ 194
           PPP    +   PP  P PP   PPP   P PP   G    +Q
Sbjct: 716 PPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQ 757



 Score = 28.5 bits (62), Expect = 6.2
 Identities = 29/99 (29%), Positives = 35/99 (35%), Gaps = 12/99 (12%)

Query: 165  PCPPGYPYPPP---PPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEA 221
            P P G   P     PPE  PG    +GAM  + P PP       PP+S    P       
Sbjct: 1211 PLPVGVEEPADSREPPE-EPGLSQ-EGAM-LLSPEPPAKEVEARPPLSPERAPEHDLEVE 1267

Query: 222  KAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKT 260
                        P       +P  +PP PP  PPE + T
Sbjct: 1268 PEPPMMLPLPLQPP------LPPPRPPRPPSPPPEPETT 1300



 Score = 28.1 bits (61), Expect = 8.1
 Identities = 13/26 (50%), Positives = 13/26 (50%), Gaps = 6/26 (23%)

Query: 156  PPPVANGMYPCPPGYPYPPPPPEFYP 181
            PPP      P PP  P PPPPP   P
Sbjct: 1539 PPP------PLPPQPPPPPPPPPVEP 1558


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 47/167 (28%), Positives = 60/167 (35%), Gaps = 16/167 (9%)

Query: 92  IKGTVKAEAGGGWEGSASYKLTFTAGGAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSG 151
           +  T   +   GW GS  +    +A  ++  G       S    G  P+G Y  S  P+G
Sbjct: 22  VSNTKPGQPPQGWPGSNPWNNP-SAPSSVPSGLPPSATPSTVPFGPAPTGMYP-SVPPTG 79

Query: 152 AYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMD-GAMGYVQPP-------PPPYPGP 203
               PP       P PP  P  PPP   YP P +   G  G    P       P PY  P
Sbjct: 80  PPPGPPA------PFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAP 133

Query: 204 MEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP 250
            +P  +GP  P    +    A      Y  P  P+    P   PPPP
Sbjct: 134 TDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPP 180



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 38/122 (31%), Positives = 41/122 (33%), Gaps = 27/122 (22%)

Query: 139 PSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPP 198
           P G +G   M SG +    P   G YP P   PYP P P  YP              PPP
Sbjct: 141 PLGPWGS--MSSGPWA---PGMGGQYPTP-NMPYPSPGP--YP-------------APPP 179

Query: 199 PYPGPMEPPVSGPDV------PSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPY 252
           P      PPV    V      P  P      +      Y  P NP  V    S  PP P 
Sbjct: 180 PQAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAPPMPG 239

Query: 253 YP 254
            P
Sbjct: 240 GP 241



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 5/76 (6%)

Query: 184 PMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVY-- 241
           P    A+   +P  PP   P   P + P  PS+  +    +   ++  + P  P  +Y  
Sbjct: 16  PAKTSAVSNTKPGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVPFGPA-PTGMYPS 74

Query: 242 -MPTSQPP-PPPYYPP 255
             PT  PP PP  +PP
Sbjct: 75  VPPTGPPPGPPAPFPP 90


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 38/114 (33%), Positives = 44/114 (38%), Gaps = 12/114 (10%)

Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY--PGPPMMDGAMGYVQPPPPPYPGPME 205
           +P G  + PPP  +G    PP    PPP PE    P P  + G  G   PPPPP PG   
Sbjct: 624 LPGGTAISPPPPLSGDATIPP----PPPLPEGVGIPSPSSLPG--GTAIPPPPPLPGSAR 677

Query: 206 PPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP----PYYPP 255
            P   P +P +             A   P  P     P   PPPP    P  PP
Sbjct: 678 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP 731



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 37/112 (33%), Positives = 43/112 (38%), Gaps = 30/112 (26%)

Query: 146 SYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG--- 202
           S +P G  + PPP   G    PP  P  P      P PP + G  G + PPPPP PG   
Sbjct: 658 SSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG-MPPPPPPLPGGPG 716

Query: 203 -PMEPPV-SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPY 252
            P  PP   GP +P  P                PG           PPPPP+
Sbjct: 717 IPPPPPFPGGPGIPPPP----------------PG--------MGMPPPPPF 744



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 32/83 (38%), Positives = 37/83 (44%), Gaps = 15/83 (18%)

Query: 148 MPSGAYVYPPPV----ANGMYPCPPGYP----YPPPPPEF-----YPGPPMMDGAMGYVQ 194
           +P  A + PPP     + G+ P PP  P     PPPPP        P PP   G  G   
Sbjct: 672 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGI-- 729

Query: 195 PPPPPYPGPMEPPVSGPDVPSTP 217
           PPPPP  G   PP  G  VP+ P
Sbjct: 730 PPPPPGMGMPPPPPFGFGVPAAP 752



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 37/117 (31%), Positives = 43/117 (36%), Gaps = 17/117 (14%)

Query: 150 SGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPP-- 207
           S A +  PP      P PP  P P       P PP    +     PPPPP P P  P   
Sbjct: 557 SAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 616

Query: 208 -VSGPDVPSTPAAEAKAAEAAASAYYN----PGNPHNVYMP--------TSQPPPPP 251
            +S P  PS P   A +     S        P  P  V +P        T+ PPPPP
Sbjct: 617 CISSP--PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 671



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 20/60 (33%), Positives = 22/60 (36%), Gaps = 20/60 (33%)

Query: 195 PPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
           PP PP PG      SG  +P  PA               PG+      P   PPPPP  P
Sbjct: 574 PPAPPLPGD-----SGTIIPPPPA---------------PGDSTTPPPPPPPPPPPPPLP 613


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 38/114 (33%), Positives = 44/114 (38%), Gaps = 12/114 (10%)

Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY--PGPPMMDGAMGYVQPPPPPYPGPME 205
           +P G  + PPP  +G    PP    PPP PE    P P  + G  G   PPPPP PG   
Sbjct: 633 LPGGTAISPPPPLSGDATIPP----PPPLPEGVGIPSPSSLPG--GTAIPPPPPLPGSAR 686

Query: 206 PPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP----PYYPP 255
            P   P +P +             A   P  P     P   PPPP    P  PP
Sbjct: 687 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP 740



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 37/112 (33%), Positives = 43/112 (38%), Gaps = 30/112 (26%)

Query: 146 SYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG--- 202
           S +P G  + PPP   G    PP  P  P      P PP + G  G + PPPPP PG   
Sbjct: 667 SSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG-MPPPPPPLPGGPG 725

Query: 203 -PMEPPV-SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPY 252
            P  PP   GP +P  P                PG           PPPPP+
Sbjct: 726 IPPPPPFPGGPGIPPPP----------------PG--------MGMPPPPPF 753



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 32/83 (38%), Positives = 37/83 (44%), Gaps = 15/83 (18%)

Query: 148 MPSGAYVYPPPV----ANGMYPCPPGYP----YPPPPPEF-----YPGPPMMDGAMGYVQ 194
           +P  A + PPP     + G+ P PP  P     PPPPP        P PP   G  G   
Sbjct: 681 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGI-- 738

Query: 195 PPPPPYPGPMEPPVSGPDVPSTP 217
           PPPPP  G   PP  G  VP+ P
Sbjct: 739 PPPPPGMGMPPPPPFGFGVPAAP 761



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 37/117 (31%), Positives = 43/117 (36%), Gaps = 17/117 (14%)

Query: 150 SGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPP-- 207
           S A +  PP      P PP  P P       P PP    +     PPPPP P P  P   
Sbjct: 566 SAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 625

Query: 208 -VSGPDVPSTPAAEAKAAEAAASAYYN----PGNPHNVYMP--------TSQPPPPP 251
            +S P  PS P   A +     S        P  P  V +P        T+ PPPPP
Sbjct: 626 CISSP--PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 680



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 20/60 (33%), Positives = 22/60 (36%), Gaps = 20/60 (33%)

Query: 195 PPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
           PP PP PG      SG  +P  PA               PG+      P   PPPPP  P
Sbjct: 583 PPAPPLPGD-----SGTIIPPPPA---------------PGDSTTPPPPPPPPPPPPPLP 622


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 36/103 (34%), Positives = 40/103 (38%), Gaps = 16/103 (15%)

Query: 157 PPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGP---DV 213
           P +A    P P   P PPPP    PG P    A     P  PP PG  EPP + P   D+
Sbjct: 528 PDLAPAAEPAPGAAPPPPPP---LPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDL 584

Query: 214 PSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPE 256
           P  P                PG    V  P   PPPPP  PP+
Sbjct: 585 PPPPPPPPPP----------PGTDGPVPPPPPPPPPPPGGPPD 617



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 27/67 (40%), Positives = 30/67 (44%), Gaps = 7/67 (10%)

Query: 156 PPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215
           PPP      P P   P PPPPP   P PP  DG +    PPPPP PG     +   D   
Sbjct: 574 PPPAP----PLPGDLPPPPPPP---PPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSEL 626

Query: 216 TPAAEAK 222
            P  +AK
Sbjct: 627 GPGVKAK 633


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 32/75 (42%), Positives = 33/75 (44%), Gaps = 3/75 (4%)

Query: 156 PPPVANGMYPCPPGYPYPPPPP---EFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPD 212
           PPP   G  P   G P PPPPP      P PP   GA G   PPPPP P P     +GP 
Sbjct: 352 PPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPA 411

Query: 213 VPSTPAAEAKAAEAA 227
            P  P A   A   A
Sbjct: 412 PPPLPPALVPAGGLA 426



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 33/99 (33%), Positives = 37/99 (37%), Gaps = 21/99 (21%)

Query: 171 PYPPPPPEF-----YPGPPMMDGAMGYVQP---------PPPPYPGPMEPPVSGPDVPST 216
           P PPPPP        P PP++ G  G   P         PPPP P    PP  G   P  
Sbjct: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPP 371

Query: 217 PAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
           P A  ++          P  P     P   PPPPP  PP
Sbjct: 372 PPATGRSGPL-------PPPPPGAGGPPMPPPPPPPPPP 403



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 27/61 (44%), Positives = 29/61 (47%), Gaps = 1/61 (1%)

Query: 157 PPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPST 216
           PPV  G+ P PP    PPPP    P PP    A G   P PPP PG   PP+  P  P  
Sbjct: 343 PPVPLGIAPPPPTPRGPPPPGRGGP-PPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPP 401

Query: 217 P 217
           P
Sbjct: 402 P 402



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 36/106 (33%), Positives = 38/106 (35%), Gaps = 37/106 (34%)

Query: 157 PPVANG-------MYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVS 209
           PP+  G       + P P G   PPPP    P PP   G      PPPPP P       S
Sbjct: 329 PPIVGGNKGRSGPLPPVPLGIA-PPPPTPRGPPPPGRGG------PPPPPPPATGR---S 378

Query: 210 GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
           GP  P  P A               G P     P   PPPPP  PP
Sbjct: 379 GPLPPPPPGA---------------GGP-----PMPPPPPPPPPPP 404



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 38/121 (31%), Positives = 40/121 (33%), Gaps = 23/121 (19%)

Query: 135 RGEVPSGAYGYSYMP------SGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDG 188
           RG  P G  G    P      SG    PPP A G    PP  P PPPPP    G      
Sbjct: 357 RGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPP-PPPPPSSGNG------ 409

Query: 189 AMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPP 248
                 P PPP P P   P  G        A              PG P +  +   QPP
Sbjct: 410 ------PAPPPLP-PALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSAL---QPP 459

Query: 249 P 249
           P
Sbjct: 460 P 460


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 41/127 (32%), Positives = 50/127 (39%), Gaps = 16/127 (12%)

Query: 145 YSYMPS---GAYVYPPPVANGMYPCPP--GYPYPPPPPEFYP---GPPMMDGAMG----- 191
           +S++PS        PPP A      PP    P PP  P   P     P    A+      
Sbjct: 378 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437

Query: 192 --YVQPPPPPYPGPMEPPVSGPDVPS-TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPP 248
             +  PP PP   P  PP S P  PS TP ++A  + AA      P  P +  M  S  P
Sbjct: 438 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497

Query: 249 PPPYYPP 255
           PP   PP
Sbjct: 498 PPQAPPP 504



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%)

Query: 165 PCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAA 224
           P PP  P   PPP+    PP +  A+  +Q PP P   P  PP+S    PS  A  A A 
Sbjct: 382 PSPPLSPLATPPPQ---APPAL--ALPPLQAPPSP---PASPPLSPLATPSPQAPNALAV 433

Query: 225 EAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ 261
               + +  P +P  V  P S P  PP  P     +Q
Sbjct: 434 HLLQAPFSPPPSPP-VQAPFSPPASPPVSPSATPPSQ 469



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 8/107 (7%)

Query: 157 PPVANGMYP---CPPGYPYPP--PPPEFYPGPPMMDGAMGYVQPPPPPYPGPME---PPV 208
           PPV+    P    PP    PP   PP     PPM   A    Q PPP    P++   PP 
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517

Query: 209 SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
             P   +TP  +A  +  A+     P +P      +    PPP  PP
Sbjct: 518 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 29/105 (27%), Positives = 36/105 (34%), Gaps = 5/105 (4%)

Query: 156 PPPVANGMYPCPPGYPYPPPPPEF---YPGPPMMDGAMGYVQPPPPPYPGPMEPPV--SG 210
           PPP A      PP    P PP  F    P  P     M  +  PPP  P  +  P+    
Sbjct: 515 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 574

Query: 211 PDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
           P  P++P  +A           +   P         PPPPP   P
Sbjct: 575 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 33/101 (32%), Positives = 37/101 (36%), Gaps = 16/101 (15%)

Query: 167 PPGYPYPPPPPEFYP--GPPMMDGAMGYVQPPP---------PPYPGPMEPPVSGPDVPS 215
           PP  P PP    F P   PP+   A    Q PP         PP P P  PP+S    P 
Sbjct: 442 PP--PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPP 498

Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQ--PPPPPYYP 254
             A    AA     A   P  P  +  P  Q  P PP  +P
Sbjct: 499 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 539



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 32/105 (30%), Positives = 38/105 (36%), Gaps = 11/105 (10%)

Query: 157 PPVANGMYP--CPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPME-----PPVS 209
           PPV     P   PP  P   PP +    PP +      V P PP  P PM      PP +
Sbjct: 446 PPVQAPFSPPASPPVSPSATPPSQ---APPSLAAPPLQVPPSPPASP-PMSPSATPPPQA 501

Query: 210 GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
            P + + P   AK    A  A   P        P S P   P+ P
Sbjct: 502 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 546



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 36/123 (29%), Positives = 44/123 (35%), Gaps = 28/123 (22%)

Query: 133 ASRGEVPSGAYGYSYMPSG-AYVYPPPVAN---------GMYPCP-------PGYPYPPP 175
           +S    P    GY   P G A   PPP A             P P       PG P P P
Sbjct: 633 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 692

Query: 176 PPEFYPGPPMMDGAMGYVQPPPP----PYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAY 231
           P     GP   DG     +   P    P PG ++P   GP  P T   +A A   A ++ 
Sbjct: 693 PA---TGPGSADGLCTIYETEGPESATPAPGALDP---GPS-PGTSGGKAAAGAGAGASS 745

Query: 232 YNP 234
            +P
Sbjct: 746 RSP 748



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 14/114 (12%)

Query: 158 PVANGMYPCPPGYPYPPPPPEFYP------GPPMMDGA--MGYVQPPPPPYPGPMEPPVS 209
           P A G  P  P +P  P P            PP  D A  +G +   P   P P     S
Sbjct: 257 PSARGT-PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS 315

Query: 210 G--PDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQP-PPPPYYPPEDKKT 260
              P +P+TP + +   + A      P +P     P+ Q  P PP  PP    T
Sbjct: 316 QAPPTLPATPHSSSLTCQLATPLPLAPPSPS--APPSLQTLPSPPATPPSQATT 367



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 17/93 (18%)

Query: 148 MPSGAYVYPPPVANGMY--------PCPPGYPY-------PPPPPEFYPGPPMMDGAMGY 192
           +P      PPP A  +         P PP  P        P P P+     P +  A+  
Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA- 608

Query: 193 VQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAE 225
             PPPPP   P    +SGPD+    ++     E
Sbjct: 609 PGPPPPPSRSPSST-LSGPDLAGHSSSATSTPE 640


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 41/127 (32%), Positives = 50/127 (39%), Gaps = 16/127 (12%)

Query: 145 YSYMPS---GAYVYPPPVANGMYPCPP--GYPYPPPPPEFYP---GPPMMDGAMG----- 191
           +S++PS        PPP A      PP    P PP  P   P     P    A+      
Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398

Query: 192 --YVQPPPPPYPGPMEPPVSGPDVPS-TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPP 248
             +  PP PP   P  PP S P  PS TP ++A  + AA      P  P +  M  S  P
Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458

Query: 249 PPPYYPP 255
           PP   PP
Sbjct: 459 PPQAPPP 465



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%)

Query: 165 PCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAA 224
           P PP  P   PPP+    PP +  A+  +Q PP P   P  PP+S    PS  A  A A 
Sbjct: 343 PSPPLSPLATPPPQ---APPAL--ALPPLQAPPSP---PASPPLSPLATPSPQAPNALAV 394

Query: 225 EAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ 261
               + +  P +P  V  P S P  PP  P     +Q
Sbjct: 395 HLLQAPFSPPPSPP-VQAPFSPPASPPVSPSATPPSQ 430



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 8/107 (7%)

Query: 157 PPVANGMYP---CPPGYPYPP--PPPEFYPGPPMMDGAMGYVQPPPPPYPGPME---PPV 208
           PPV+    P    PP    PP   PP     PPM   A    Q PPP    P++   PP 
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478

Query: 209 SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
             P   +TP  +A  +  A+     P +P      +    PPP  PP
Sbjct: 479 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 525



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 29/105 (27%), Positives = 36/105 (34%), Gaps = 5/105 (4%)

Query: 156 PPPVANGMYPCPPGYPYPPPPPEF---YPGPPMMDGAMGYVQPPPPPYPGPMEPPV--SG 210
           PPP A      PP    P PP  F    P  P     M  +  PPP  P  +  P+    
Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535

Query: 211 PDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
           P  P++P  +A           +   P         PPPPP   P
Sbjct: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 33/101 (32%), Positives = 37/101 (36%), Gaps = 16/101 (15%)

Query: 167 PPGYPYPPPPPEFYP--GPPMMDGAMGYVQPPP---------PPYPGPMEPPVSGPDVPS 215
           PP  P PP    F P   PP+   A    Q PP         PP P P  PP+S    P 
Sbjct: 403 PP--PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPP 459

Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQ--PPPPPYYP 254
             A    AA     A   P  P  +  P  Q  P PP  +P
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 500



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 32/105 (30%), Positives = 38/105 (36%), Gaps = 11/105 (10%)

Query: 157 PPVANGMYP--CPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPME-----PPVS 209
           PPV     P   PP  P   PP +    PP +      V P PP  P PM      PP +
Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQ---APPSLAAPPLQVPPSPPASP-PMSPSATPPPQA 462

Query: 210 GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
            P + + P   AK    A  A   P        P S P   P+ P
Sbjct: 463 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 507



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 10/79 (12%)

Query: 165 PCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG--------PMEPPVSGPDVPST 216
           P PPG P PPPP    P    + GA G V   P             P   P +GP   S 
Sbjct: 27  PRPPGSPRPPPP--VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSR 84

Query: 217 PAAEAKAAEAAASAYYNPG 235
           P A  +   A  +   +PG
Sbjct: 85  PPASGRGERAPPAKNTSPG 103



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 36/123 (29%), Positives = 44/123 (35%), Gaps = 28/123 (22%)

Query: 133 ASRGEVPSGAYGYSYMPSG-AYVYPPPVAN---------GMYPCP-------PGYPYPPP 175
           +S    P    GY   P G A   PPP A             P P       PG P P P
Sbjct: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 653

Query: 176 PPEFYPGPPMMDGAMGYVQPPPP----PYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAY 231
           P     GP   DG     +   P    P PG ++P   GP  P T   +A A   A ++ 
Sbjct: 654 PA---TGPGSADGLCTIYETEGPESATPAPGALDP---GPS-PGTSGGKAAAGAGAGASS 706

Query: 232 YNP 234
            +P
Sbjct: 707 RSP 709



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 37/165 (22%), Positives = 60/165 (36%), Gaps = 23/165 (13%)

Query: 97  KAEAGGGWEGSASYKLTFTAGGAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYP 156
           +  AGGG +  AS  L+ +A       +     +  ++RG   + A+     P G     
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPAR-----SGPSARGTPRAPAHPSQPKPKGLQALR 272

Query: 157 PPVANGMYPCPPGYPYPPPPPEFYPG-PPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215
           PP               PP  +  P   P+    +    P  PP P       + P  P+
Sbjct: 273 PPQVT------------PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320

Query: 216 TPAAEAKAAEAA----ASAYYNPGNPHN-VYMPTSQPPPPPYYPP 255
           TP ++A  +  +    A+  + P  P + +  P  Q PP    PP
Sbjct: 321 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 17/93 (18%)

Query: 148 MPSGAYVYPPPVANGMY--------PCPPGYPY-------PPPPPEFYPGPPMMDGAMGY 192
           +P      PPP A  +         P PP  P        P P P+     P +  A+  
Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA- 569

Query: 193 VQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAE 225
             PPPPP   P    +SGPD+    ++     E
Sbjct: 570 PGPPPPPSRSPSST-LSGPDLAGHSSSATSTPE 601


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 35/108 (32%), Positives = 42/108 (38%), Gaps = 8/108 (7%)

Query: 156 PPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMG-------YVQPPPPPYPGPMEPPV 208
           PP +A      PP  P  PP        P    A+        +  PP PP   P  PP 
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681

Query: 209 SGPDVPS-TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
           S P  PS TP ++A  + AA      P  P +  M  S  PPP   PP
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 39/114 (34%), Positives = 48/114 (42%), Gaps = 17/114 (14%)

Query: 156 PPPVANGMYPCPP--GYPYPP------PPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPP 207
           PPP A      PP  G P PP      PPP+    PP +  A+  +Q PP P   P  PP
Sbjct: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQ---APPXL--ALPPLQAPPSP---PASPP 641

Query: 208 VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ 261
           +S    PS  A  A A     + +  P +P  V  P S P  PP  P     +Q
Sbjct: 642 LSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPSATPPSQ 694



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 38/108 (35%), Positives = 45/108 (41%), Gaps = 13/108 (12%)

Query: 157 PPVANGMYP---CPPGYPYPP--PPPEFYPGPPMMDGAMGYVQPPPPPYPGPME----PP 207
           PPV+    P    PP    PP   PP     PPM   A    Q PPP    P++    PP
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP 742

Query: 208 VSGPDVPS-TPAAEAKAAEAAASAYYNPGNPHNVYM-PTSQPPP--PP 251
            S P  PS TP        AA      P  P ++ M P ++PPP  PP
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 35/95 (36%), Positives = 38/95 (40%), Gaps = 9/95 (9%)

Query: 167 PPGYPYPPPPPEFYP--GPPMMDGAMGYVQPPP----PPYPGPMEPPVSGPDVPS-TPAA 219
           PP  P PP    F P   PP+   A    Q PP    PP   P  PP S P  PS TP  
Sbjct: 667 PP--PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724

Query: 220 EAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
           +A    AA      P  P +  M  S  PPP   P
Sbjct: 725 QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 30/113 (26%), Positives = 38/113 (33%), Gaps = 5/113 (4%)

Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPPPPEF---YPGPPMMDGAMGYVQPPPPPYPGPM 204
           +P      PPP A      PP    P PP  F    P  P     M  +  PPP  P  +
Sbjct: 776 LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835

Query: 205 EPPV--SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
             P+    P  P++P  +A           +   P         PPPPP   P
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 32/104 (30%), Positives = 39/104 (37%), Gaps = 7/104 (6%)

Query: 149 PSGAYVYP-PPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPP 207
           PSG    P PP  N   P P   P  PP     P  P    A   +Q  P P   P  PP
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP---PATPP 365

Query: 208 VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251
              P   +TP  +A  +            PH++  P+ Q PP P
Sbjct: 366 SQAPPSMTTPPMQAPPSLQTIPPIQ---VPHSLTSPSLQAPPSP 406



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 29/93 (31%), Positives = 35/93 (37%), Gaps = 15/93 (16%)

Query: 165 PCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSG-PDVPSTPAAEAKA 223
           PCP   P   PP      PP    ++    PPP   P    PP+ G P  P +P A    
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIA--TPPPQAPPALASPPLQGLPSPPLSPLATPP- 618

Query: 224 AEAAASAYYNPGNPHNVYMPTSQ-PPPPPYYPP 255
                     P  P  + +P  Q PP PP  PP
Sbjct: 619 ----------PQAPPXLALPPLQAPPSPPASPP 641



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 38/123 (30%), Positives = 45/123 (36%), Gaps = 20/123 (16%)

Query: 149 PSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPP----PPYPGPM 204
           P      PPP A      PP    PP PP     PPM   A    + PP    PP   P 
Sbjct: 715 PMSPSATPPPQAPPPLAAPP-LQVPPSPPA---SPPMSPSATPPPRVPPLLAAPPLQVPP 770

Query: 205 EPPVSGPDVP-STPAAEAKAAEAAASAYYNPGNPHNV-----YMPTSQPP------PPPY 252
            PP S P  P + P  +A  A A       P  P +      + P++  P      PPP 
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830

Query: 253 YPP 255
            PP
Sbjct: 831 APP 833



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 19/114 (16%)

Query: 157 PPVANGMYPCPPGYPYPP-----PPPEFYPG--PPMMDGAMG-----YVQPPPPPYPGPM 204
           PP+       PP    PP     PP E  P   PP +  A       +++ PP P P P+
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569

Query: 205 EPPVS-----GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPP--PP 251
           + P S      P+ PS+ A     A  A ++    G P     P + PPP  PP
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 36/123 (29%), Positives = 44/123 (35%), Gaps = 28/123 (22%)

Query: 133  ASRGEVPSGAYGYSYMPSG-AYVYPPPVAN---------GMYPCP-------PGYPYPPP 175
            +S    P    GY   P G A   PPP A             P P       PG P P P
Sbjct: 902  SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 961

Query: 176  PPEFYPGPPMMDGAMGYVQPPPP----PYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAY 231
            P     GP   DG     +   P    P PG ++P   GP  P T   +A A   A ++ 
Sbjct: 962  PA---TGPGSADGLCTIYETEGPESATPAPGALDP---GPS-PGTSGGKAAAGAGAGASS 1014

Query: 232  YNP 234
             +P
Sbjct: 1015 RSP 1017



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 17/93 (18%)

Query: 148 MPSGAYVYPPPVANGMY--------PCPPGYPY-------PPPPPEFYPGPPMMDGAMGY 192
           +P      PPP A  +         P PP  P        P P P+     P +  A+  
Sbjct: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA- 877

Query: 193 VQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAE 225
             PPPPP   P    +SGPD+    ++     E
Sbjct: 878 PGPPPPPSRSPSST-LSGPDLAGHSSSATSTPE 909


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 36/104 (34%), Positives = 42/104 (40%), Gaps = 23/104 (22%)

Query: 171 PYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVS-----------------GPD- 212
           P+  PPP   P P M  G  G  QPPPPP P P  P +S                 GP  
Sbjct: 78  PHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPG 137

Query: 213 -VPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
            VP    +  ++      +Y  P      YMP  Q PPP YYPP
Sbjct: 138 LVPMELESPPESPPVPPGSYMPPSQS---YMPPPQ-PPPSYYPP 177



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 35/123 (28%), Positives = 51/123 (41%), Gaps = 32/123 (26%)

Query: 157 PPVANGMYPCPPGYPY---PPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDV 213
           PPV  G Y  PP   Y   P PPP +YP       +  Y+   PP  P P + P S   +
Sbjct: 150 PPVPPGSY-MPPSQSYMPPPQPPPSYYP----PTSSQPYL---PPAQPSPSQSPPSQSYL 201

Query: 214 PSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQ----------------PPPPPYYPPED 257
             TP+  + ++ + +   ++       Y+P+SQ                 PPPP  PP +
Sbjct: 202 APTPSYSSSSSSSQSYLSHSQS-----YLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGN 256

Query: 258 KKT 260
           K T
Sbjct: 257 KTT 259



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 40/129 (31%), Positives = 46/129 (35%), Gaps = 30/129 (23%)

Query: 156 PPPVANGMYPC---PPGYP-----------YPPP------PPEFYPGPPMMDGAMGYVQP 195
           PPPV     P    PPG P            PPP      PP   P P +   A   V P
Sbjct: 561 PPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMP 620

Query: 196 PPP-----PYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPT----SQ 246
            PP     P PG   P V     P   AA    A ++ S+   P  P    +PT      
Sbjct: 621 LPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQV-PEKPRPALLPTPVSFGS 679

Query: 247 PPPPPYYPP 255
            PP  Y+PP
Sbjct: 680 APPTTYHPP 688



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 26/62 (41%), Positives = 27/62 (43%), Gaps = 13/62 (20%)

Query: 162  GMYPCPPGYPYPPPPPEFYPG-------PPMMDGAMGY-----VQPPPPPYPGPMEPPVS 209
            GMYP PPG   PPPP    PG       PP             + PPPPP P P  PPV 
Sbjct: 1504 GMYP-PPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVI 1562

Query: 210  GP 211
             P
Sbjct: 1563 KP 1564



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 15/103 (14%)

Query: 156 PPPVANGMYPCPPGYPYPPPP--PEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDV 213
           PPP        PP  P  PPP  P   P PP+M  A+    PPP      M PPV  P +
Sbjct: 517 PPPFVP-YSQMPPPLPTMPPPVLPPSLP-PPVMPPALPATVPPP-----GMPPPVMPPSL 569

Query: 214 PSTPAAEAKAAEAAASAYYNPGNPHNVYMPT-SQPPPPPYYPP 255
           P++          +++     G P  +  P+ S   PPP  PP
Sbjct: 570 PTSVPPPGMPPSLSSA-----GPPPVLPPPSLSSAGPPPVLPP 607



 Score = 36.2 bits (82), Expect = 0.030
 Identities = 31/111 (27%), Positives = 40/111 (36%), Gaps = 14/111 (12%)

Query: 145 YSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPM 204
           YS MP      PPPV     P P     PP  P   P P M          PPP  P  +
Sbjct: 523 YSQMPPPLPTMPPPVLPPSLPPPV---MPPALPATVPPPGM----------PPPVMPPSL 569

Query: 205 EPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPT-SQPPPPPYYP 254
              V  P +P + ++          +  + G P  +  P+ S   PPP  P
Sbjct: 570 PTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMP 620



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 15/62 (24%)

Query: 149  PSGAYVYP--PPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEP 206
            P G+ V P  PP  + +    P  P PPPPP     PP+         PPPPP   P   
Sbjct: 1521 PPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP----PPL---------PPPPPVIKPQTS 1567

Query: 207  PV 208
             V
Sbjct: 1568 AV 1569



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 26/86 (30%), Positives = 30/86 (34%), Gaps = 19/86 (22%)

Query: 180 YPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAA----------EAKAAEAAAS 229
           YP PP+         PPPPP   P   P  G    +TPAA          E   A+    
Sbjct: 14  YPPPPV---------PPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQL 64

Query: 230 AYYNPGNPHNVYMPTSQPPPPPYYPP 255
              +      V  P   PPPP   PP
Sbjct: 65  QQMHQKQMQCVLQPHHLPPPPLPPPP 90



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 2/61 (3%)

Query: 201 PGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKT 260
           PG  + PV   D P  P  E     A +    +P +      P ++  PPP  PPE+ ++
Sbjct: 314 PGHKKGPVVAKDTPE-PVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPP-LPPEEPQS 371

Query: 261 Q 261
           +
Sbjct: 372 E 372


>gi|41281808 harmonin isoform b3 [Homo sapiens]
          Length = 899

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 36/130 (27%), Positives = 53/130 (40%), Gaps = 23/130 (17%)

Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPP--PPEFYPGPPMMD-------GAMGYVQPPPP 198
           +P   + YPP   + +    P  P+PPP  PP   P PP++         +  +VQ  PP
Sbjct: 546 IPLDMFYYPPKTPSAL----PVMPHPPPSNPPHKVPAPPVLPLSGHVSASSSPWVQRTPP 601

Query: 199 PYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVY----------MPTSQPP 248
           P P P  P V   D+  T    +   EA ++  +  G+  N             PT+ P 
Sbjct: 602 PIPIPPPPSVPTQDLTPTRPLPSALEEALSNHPFRTGDTGNPVEDWEAKNHSGKPTNSPV 661

Query: 249 PPPYYPPEDK 258
           P   +PP  K
Sbjct: 662 PEQSFPPTPK 671



 Score = 28.9 bits (63), Expect = 4.7
 Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 11/65 (16%)

Query: 195 PPPPPYPGPMEPPV----SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP 250
           PPPPP   P+ PP+     G  + +T   +          YY P  P  + +    P PP
Sbjct: 516 PPPPPSVSPLAPPLRRFAGGLHLHTTDLDDI----PLDMFYYPPKTPSALPV---MPHPP 568

Query: 251 PYYPP 255
           P  PP
Sbjct: 569 PSNPP 573


>gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens]
          Length = 407

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 46/154 (29%), Positives = 59/154 (38%), Gaps = 31/154 (20%)

Query: 118 GAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVY---------PPPVANGMYPCPP 168
           GA ++G R++  A+    G+ P   +   Y P G +V          PPP   G  P PP
Sbjct: 202 GASQWGSRVVPNAANGWAGQPPP-TWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPP 260

Query: 169 ------------GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPST 216
                       G+P P   P+ Y  PP    + GY  PPPPP       P   P  P+T
Sbjct: 261 PFTSYIVSTPPGGFPPPQGFPQGYGAPPQF--SFGYGPPPPPP---DQFAPPGVPPPPAT 315

Query: 217 PAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP 250
           P A   A     S       P     PT+QP  P
Sbjct: 316 PGAAPLAFPPPPS----QAAPDMSKPPTAQPDFP 345



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 27/102 (26%), Positives = 30/102 (29%), Gaps = 34/102 (33%)

Query: 144 GYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYP---GPPMMDGAMGYVQPP---- 196
           GY   P  ++ Y PP        PPG P PP  P   P    PP    A    +PP    
Sbjct: 283 GYGAPPQFSFGYGPPPPPPDQFAPPGVPPPPATPGAAPLAFPPPPSQAAPDMSKPPTAQP 342

Query: 197 ---------------------------PPPYPGPMEPPVSGP 211
                                      PP Y GP  P   GP
Sbjct: 343 DFPYGQYAGYGQDLSGFGQGFSDPSQQPPSYGGPSVPGSGGP 384


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 38/105 (36%), Positives = 42/105 (40%), Gaps = 15/105 (14%)

Query: 165 PCPP--GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPY---------PGPMEPPVSGPDV 213
           P PP  G P PPPPP    GPP    A G   PPPPP          P P  P V+ P  
Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPP-PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPP 337

Query: 214 PSTPAAEAKAAEAAASAYYNPGNPHNVYM---PTSQPPPPPYYPP 255
           P             +SA   P  P    +   P + PPPPP  PP
Sbjct: 338 PPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPP 382



 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 39/111 (35%), Positives = 43/111 (38%), Gaps = 14/111 (12%)

Query: 156 PPPVANGMYPCPPGYPY---PPPPPEFYPG-PPMMDGAMGYVQPPPPPYPGPMEPPVSGP 211
           PPP + G  P PP  P+   PPPPP    G PP          PPPPP   P  P V+ P
Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPP---PSRPSVAVP 335

Query: 212 DVPSTPAAEAKAAEAAASAYYNPGNPHN-------VYMPTSQPPPPPYYPP 255
             P             +SA   P  P         V  P   PPPPP  PP
Sbjct: 336 PPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPP 386



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 30/65 (46%), Positives = 33/65 (50%), Gaps = 11/65 (16%)

Query: 156 PPPVANGMYPCPP-----GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSG 210
           PPP  N MYP PP       P  PPPP     PP + G +G V PPPPP P P   P   
Sbjct: 335 PPPPPNRMYPPPPPALPSSAPSGPPPP-----PPSVLG-VGPVAPPPPPPPPPPPGPPPP 388

Query: 211 PDVPS 215
           P +PS
Sbjct: 389 PGLPS 393



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 38/109 (34%), Positives = 40/109 (36%), Gaps = 13/109 (11%)

Query: 156 PPPVANGMYPCPP--GYPYPPPPPEFYPG---PPMMDGAMGYVQPPPPP---YPGPMEPP 207
           PPP  N   P PP  G   PPPPP   P    PP          PPPPP   YP P  PP
Sbjct: 291 PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPP--PP 348

Query: 208 VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPE 256
                 PS P     +          P  P     P   PPPPP  P +
Sbjct: 349 ALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP---PPPGPPPPPGLPSD 394



 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 31/90 (34%), Positives = 35/90 (38%), Gaps = 21/90 (23%)

Query: 171 PYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAA------ 224
           P PPPP    P PP          PPPP   GP  PP  G   P  P + A  A      
Sbjct: 277 PPPPPPSRGGPPPP----------PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPP 326

Query: 225 EAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
            +  S    P  P+ +Y     PPPPP  P
Sbjct: 327 PSRPSVAVPPPPPNRMY-----PPPPPALP 351



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 30/81 (37%), Positives = 31/81 (38%), Gaps = 21/81 (25%)

Query: 149 PSGAYVYPPPVANGMYPCPPGYPY----PPPPPEFYPGPP--MMDGAMGYVQPPPP---- 198
           PS A    PP      P PP  P     PPPP   YP PP  +   A     PPPP    
Sbjct: 314 PSRAPTAAPP------PPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLG 367

Query: 199 -----PYPGPMEPPVSGPDVP 214
                P P P  PP  GP  P
Sbjct: 368 VGPVAPPPPPPPPPPPGPPPP 388



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 11/54 (20%)

Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYP 201
           +PS A   PPP    +    P  P PPPPP   PGP           PPPP  P
Sbjct: 350 LPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGP-----------PPPPGLP 392



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 18/38 (47%), Positives = 18/38 (47%), Gaps = 6/38 (15%)

Query: 146 SYMPSGAYVYPP------PVANGMYPCPPGYPYPPPPP 177
           S  PSG    PP      PVA    P PP  P PPPPP
Sbjct: 352 SSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPP 389


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 39/121 (32%), Positives = 44/121 (36%), Gaps = 11/121 (9%)

Query: 136 GEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQP 195
           G   S     S+ P    +  PP     +  PP  P PPPP    P PP   G      P
Sbjct: 288 GPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTP 347

Query: 196 PPPPYPG-PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254
           PPP  P  P  P  + P  P  P A          A Y    P  +  PT   PPPP  P
Sbjct: 348 PPPSPPSFPPHPDFAAPPPPPPPPA----------ADYPTLPPPPLSQPTGGAPPPPPPP 397

Query: 255 P 255
           P
Sbjct: 398 P 398



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 37/116 (31%), Positives = 43/116 (37%), Gaps = 34/116 (29%)

Query: 147 YMPSGAYVYPPPVANGMYPCPP-------GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPP 199
           + P  A   PPP   G+ P PP       G P PP PP F P P        +  PPPPP
Sbjct: 316 FAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD-------FAAPPPPP 368

Query: 200 YPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
            P    P    P +P  P ++                P     P   PPPPP  PP
Sbjct: 369 PP----PAADYPTLPPPPLSQ----------------PTGGAPPPPPPPPPPGPPP 404



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 27/65 (41%), Positives = 32/65 (49%), Gaps = 8/65 (12%)

Query: 156 PPPVANGMYPCPPGYPYPPPPPE----FYPG--PPMMDGAMGYVQPPPP--PYPGPMEPP 207
           PPP +   +P  P +  PPPPP      YP   PP +    G   PPPP  P PGP  PP
Sbjct: 347 PPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP 406

Query: 208 VSGPD 212
            +G D
Sbjct: 407 FTGAD 411



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 39/110 (35%), Positives = 45/110 (40%), Gaps = 35/110 (31%)

Query: 155 YPPPVAN-GMYPCP-PGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPP--YPGPMEPPVSG 210
           +PPP    G  P P PG+  PP PP   P PP M G    + PPPPP  +  P  PP   
Sbjct: 299 HPPPAPPLGSPPGPKPGFAPPPAPP---PPPPPMIG----IPPPPPPVGFGSPGTPPPPS 351

Query: 211 PDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKT 260
           P  PS P                   PH  +   + PPPPP  P  D  T
Sbjct: 352 P--PSFP-------------------PHPDF---AAPPPPPPPPAADYPT 377



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 31/111 (27%), Positives = 42/111 (37%), Gaps = 8/111 (7%)

Query: 151 GAYVYPPPVA--NGMYPCPPGYP---YPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPME 205
           G   YPP +   NG   C        YPPPP       P    +   + PPP  +  P++
Sbjct: 220 GTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVD 279

Query: 206 -PPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
               SG   P   +  + +    A    +P  P   + P   PPPPP  PP
Sbjct: 280 NQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPP--PP 328



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 30/90 (33%), Positives = 35/90 (38%), Gaps = 11/90 (12%)

Query: 146 SYMPSGAYVYPPPVANGMYPCPPGYPYP--PPPPEFYP--GPPMMDGAMGYVQPPPPPYP 201
           S+ P   +  PPP      P PP   YP  PPPP   P  G P          PPPPP+ 
Sbjct: 354 SFPPHPDFAAPPPP-----PPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFT 408

Query: 202 GPMEPPVSGPDVPST--PAAEAKAAEAAAS 229
           G    P   P +  T  P +   A   A S
Sbjct: 409 GADGQPAIPPPLSDTTKPKSSLPAVSDARS 438



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 29/76 (38%), Positives = 33/76 (43%), Gaps = 12/76 (15%)

Query: 139 PSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPP-P 197
           P  A  Y  +P      PPP++      PP    PPPPP   P PP   GA G  QP  P
Sbjct: 369 PPPAADYPTLP------PPPLSQPTGGAPPP---PPPPPPPGPPPPPFTGADG--QPAIP 417

Query: 198 PPYPGPMEPPVSGPDV 213
           PP     +P  S P V
Sbjct: 418 PPLSDTTKPKSSLPAV 433


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 28/70 (40%), Positives = 31/70 (44%), Gaps = 16/70 (22%)

Query: 156 PPPVANG------MYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVS 209
           PPP+  G        P PPG P PPP P   P PP          PPPPP P  + PP  
Sbjct: 316 PPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP----------PPPPPLPNQVPPPPP 365

Query: 210 GPDVPSTPAA 219
            P  P  PA+
Sbjct: 366 PPPAPPLPAS 375



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 24/83 (28%)

Query: 173 PPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYY 232
           PPPPP   PGP     A+    PPPP  P P   P +GP  P  P               
Sbjct: 313 PPPPPPLPPGPAQASVAL----PPPPGPPPPPPLPSTGPPPPPPP--------------- 353

Query: 233 NPGNPHNVYMPTSQPPPPPYYPP 255
            P  P+ V      PPPPP  PP
Sbjct: 354 -PPLPNQV----PPPPPPPPAPP 371


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 28/70 (40%), Positives = 31/70 (44%), Gaps = 16/70 (22%)

Query: 156 PPPVANG------MYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVS 209
           PPP+  G        P PPG P PPP P   P PP          PPPPP P  + PP  
Sbjct: 316 PPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP----------PPPPPLPNQVPPPPP 365

Query: 210 GPDVPSTPAA 219
            P  P  PA+
Sbjct: 366 PPPAPPLPAS 375



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 24/83 (28%)

Query: 173 PPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYY 232
           PPPPP   PGP     A+    PPPP  P P   P +GP  P  P               
Sbjct: 313 PPPPPPLPPGPAQASVAL----PPPPGPPPPPPLPSTGPPPPPPP--------------- 353

Query: 233 NPGNPHNVYMPTSQPPPPPYYPP 255
            P  P+ V      PPPPP  PP
Sbjct: 354 -PPLPNQV----PPPPPPPPAPP 371


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 44/131 (33%), Positives = 46/131 (35%), Gaps = 24/131 (18%)

Query: 149 PSGAYVYPPPVANG--MYPCPPGYPYPPPP-------PEFYPGPPMMDGAMGYVQPP-PP 198
           P G    PPP        P PPG P  PPP       P   PG P      G  QP  PP
Sbjct: 53  PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 112

Query: 199 PYPG-PMEPP------VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV-----YMPTSQ 246
           P PG P  PP        GP  P  P       + + S    PG P          P   
Sbjct: 113 PPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 172

Query: 247 PPPP--PYYPP 255
           PPPP  P  PP
Sbjct: 173 PPPPGKPQGPP 183



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 42/131 (32%), Positives = 45/131 (34%), Gaps = 24/131 (18%)

Query: 149 PSGAYVYPPPVANG--MYPCPPGYPYPPPP-------PEFYPGPPMMDGAMGYVQ---PP 196
           P G    PPP        P PPG P  PPP       P   PG P      G  Q   PP
Sbjct: 114 PPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 173

Query: 197 PPPYPGPMEPP-----VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV-----YMPTSQ 246
           PPP      PP       GP  P  P       + + S+   PG P          P   
Sbjct: 174 PPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP 233

Query: 247 PPPP--PYYPP 255
           PPPP  P  PP
Sbjct: 234 PPPPGKPQGPP 244



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 30/101 (29%), Positives = 35/101 (34%), Gaps = 6/101 (5%)

Query: 156 PPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG-PMEPPVSGPDVP 214
           PP    G  P     P  PPPP   PG P      G  +P  PP PG P  PP  G    
Sbjct: 215 PPGKPQGPPPQGGNQPQGPPPP---PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGS-- 269

Query: 215 STPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255
            + +A +   +          NP     P    P  P  PP
Sbjct: 270 KSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 310



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 36/127 (28%), Positives = 42/127 (33%), Gaps = 32/127 (25%)

Query: 146 SYMPSGAYVYPPPVANGMY---PCPPGYPY------------PPPPPEFYPGPPMMDGAM 190
           S  P G    PPP         P PPG P             PPPP +   GPP   G+ 
Sbjct: 212 SQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPAQGGSK 270

Query: 191 GYVQPPPPPYP-GPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPP 249
                 PP  P GP +   + P  P  PA                GNP     P +  P 
Sbjct: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAG---------------GNPQQPQAPPAGQPQ 315

Query: 250 PPYYPPE 256
            P  PP+
Sbjct: 316 GPPRPPQ 322



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 33/102 (32%), Positives = 37/102 (36%), Gaps = 21/102 (20%)

Query: 161 NGMYPCPPG--YPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG-PMEPPVSGPD--VPS 215
           N   P P G   P  PPPP   PG P      G  +P  PP PG P  PP  G     P 
Sbjct: 35  NPQGPSPQGGNKPQGPPPP---PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91

Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP--PYYPP 255
           +P  + +              P     P   PPPP  P  PP
Sbjct: 92  SPPGKPQGPP-----------PQGGNQPQGPPPPPGKPQGPP 122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.135    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,489,330
Number of Sequences: 37866
Number of extensions: 1281988
Number of successful extensions: 23442
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 651
Number of HSP's successfully gapped in prelim test: 1044
Number of HSP's that attempted gapping in prelim test: 7127
Number of HSP's gapped (non-prelim): 8619
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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