BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24430132 WW domain binding protein 2 [Homo sapiens] (261 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24430132 WW domain binding protein 2 [Homo sapiens] 560 e-160 gi|224593260 WBP2 N-terminal like [Homo sapiens] 140 9e-34 gi|59806357 submaxillary gland androgen regulated protein 3 homo... 59 4e-09 gi|157168329 formin 1 [Homo sapiens] 58 7e-09 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 58 7e-09 gi|150417989 cyclin K isoform 1 [Homo sapiens] 58 1e-08 gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 57 2e-08 gi|160707881 formin 2 [Homo sapiens] 55 5e-08 gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 55 6e-08 gi|25470890 DAZ associated protein 1 isoform a [Homo sapiens] 55 8e-08 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 55 8e-08 gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 54 1e-07 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 54 1e-07 gi|210032580 SET domain containing 1B [Homo sapiens] 54 1e-07 gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho... 54 1e-07 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 54 2e-07 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 54 2e-07 gi|33356148 formin-like 1 [Homo sapiens] 54 2e-07 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 53 2e-07 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 53 3e-07 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 53 3e-07 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 52 4e-07 gi|146134388 YLP motif containing 1 [Homo sapiens] 52 4e-07 gi|41281808 harmonin isoform b3 [Homo sapiens] 52 5e-07 gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens] 52 5e-07 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 52 7e-07 gi|11386183 WAS protein family, member 2 [Homo sapiens] 52 7e-07 gi|56549694 enabled homolog isoform a [Homo sapiens] 51 9e-07 gi|39930375 enabled homolog isoform b [Homo sapiens] 51 9e-07 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 51 1e-06 >gi|24430132 WW domain binding protein 2 [Homo sapiens] Length = 261 Score = 560 bits (1442), Expect = e-160 Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFL 60 MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFL Sbjct: 1 MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFL 60 Query: 61 SKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAGGAI 120 SKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAGGAI Sbjct: 61 SKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAGGAI 120 Query: 121 EFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY 180 EFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY Sbjct: 121 EFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY 180 Query: 181 PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV 240 PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV Sbjct: 181 PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV 240 Query: 241 YMPTSQPPPPPYYPPEDKKTQ 261 YMPTSQPPPPPYYPPEDKKTQ Sbjct: 241 YMPTSQPPPPPYYPPEDKKTQ 261 >gi|224593260 WBP2 N-terminal like [Homo sapiens] Length = 309 Score = 140 bits (354), Expect = 9e-34 Identities = 92/229 (40%), Positives = 118/229 (51%), Gaps = 34/229 (14%) Query: 1 MALNKNHSEGG-GVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIF 59 MA+N++H+E G ++ N ES+L +VEL+F F G K GT++LT YRVIF Sbjct: 1 MAVNQSHTENRRGALIPNGESLLKRSPNVELSFPQRSEGSNVFSGRKTGTLFLTSYRVIF 60 Query: 60 LSKGK--DAMQSFMMPFYLMKDCEIKQPVFGANYIKGTVKAEAGGGWEGSASYKLTFTAG 117 ++ D M SFMMPF LM + ++QPVF AN+IKGT++A GGWEG A++KL F G Sbjct: 61 ITSCSISDPMLSFMMPFDLMTNLTVEQPVFAANFIKGTIQAAPYGGWEGQATFKLVFRNG 120 Query: 118 GAIEFGQRMLQVASQASRG-----------------EVPSGAYGYSYMPSGAYVYPPPVA 160 AIEF Q M++ AS A+RG G MP VY P A Sbjct: 121 DAIEFAQLMVKAASAAARGFPLRTLNDWFSSMGIYVITGEGNMCTPQMPCSVIVYGAPPA 180 Query: 161 NGMYPCPPGYPYPPP-----------PPEFYPGPPMMDGA--MGYVQPP 196 P PPGY PP PP Y P+ GA +GY PP Sbjct: 181 GYGAP-PPGYGAPPAGYGAQPVGNEGPPVGYRASPVRYGAPPLGYGAPP 228 >gi|59806357 submaxillary gland androgen regulated protein 3 homolog A precursor [Homo sapiens] Length = 134 Score = 58.9 bits (141), Expect = 4e-09 Identities = 37/99 (37%), Positives = 43/99 (43%), Gaps = 16/99 (16%) Query: 165 PCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPP-PPPY-PGPMEPPVSGP-------DVPS 215 P PPG PPPPP F G G+V PP PPPY PG PP+S P P Sbjct: 29 PYPPGPLAPPPPPCFPFGT-------GFVPPPHPPPYGPGRFPPPLSPPYGPGRIPPSPP 81 Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 P + + Y PG P P PP PP++P Sbjct: 82 PPYGPGRIQSHSLPPPYGPGYPQPPSQPRPYPPGPPFFP 120 Score = 48.9 bits (115), Expect = 4e-06 Identities = 33/99 (33%), Positives = 41/99 (41%), Gaps = 20/99 (20%) Query: 139 PSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPY------PPPPPEFYPG--------PP 184 P +G ++P +PPP G +P P PY P PPP + PG PP Sbjct: 41 PCFPFGTGFVPPP---HPPPYGPGRFPPPLSPPYGPGRIPPSPPPPYGPGRIQSHSLPPP 97 Query: 185 MMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKA 223 GY QPP P P P PP + P+ PA A Sbjct: 98 Y---GPGYPQPPSQPRPYPPGPPFFPVNSPTDPALPTPA 133 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 58.2 bits (139), Expect = 7e-09 Identities = 34/91 (37%), Positives = 37/91 (40%), Gaps = 10/91 (10%) Query: 167 PPGYPYPPPPP------EFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAE 220 PP PPPPP P PPM + G PPPPP P P+ PP S P P Sbjct: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPP 706 Query: 221 AKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251 + A NPG P P PPPP Sbjct: 707 LPNSPAPP----NPGGPPPAPPPPGLAPPPP 733 Score = 40.0 bits (92), Expect = 0.002 Identities = 31/83 (37%), Positives = 34/83 (40%), Gaps = 15/83 (18%) Query: 138 VPSGAYGYSYMP------SGAYVYPPPVANGMYPCPP--GYPYPPPPPEF--YPGPPMMD 187 +PSG S P +G + PPP P P G P PPPPP P PP Sbjct: 658 LPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPG 717 Query: 188 GAMGYVQPPPPPYPGPMEPPVSG 210 G PP PP PG PP G Sbjct: 718 GP-----PPAPPPPGLAPPPPPG 735 Score = 31.6 bits (70), Expect = 0.73 Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 7/58 (12%) Query: 156 PPPVANGMYPCPPGYP--YPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG-----PMEP 206 PPP+ N P PG P PPPP P PP + +G P P PM+P Sbjct: 704 PPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 58.2 bits (139), Expect = 7e-09 Identities = 41/123 (33%), Positives = 46/123 (37%), Gaps = 12/123 (9%) Query: 139 PSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQP-PP 197 P G G P V PPP+A PP PPPP +PG P +G + P PP Sbjct: 243 PPGPPGPPGPPPPGQVLPPPLAG-----PPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP 297 Query: 198 PPYPG-----PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPY 252 PP PG PP GP P P P PH P PPP P+ Sbjct: 298 PPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP-PPHLPGPPPGAPPPAPH 356 Query: 253 YPP 255 P Sbjct: 357 VNP 359 Score = 55.5 bits (132), Expect = 5e-08 Identities = 50/143 (34%), Positives = 63/143 (44%), Gaps = 26/143 (18%) Query: 129 VASQASRGEVPSGAYGYSYMPSGAYVYPP--PVANGMYPCPPGY-PYP-PPPPEFYPGPP 184 +A +RG+ P + P G PP P+ G P PGY P P PPPP+ P PP Sbjct: 263 LAGPPNRGDRPPPPVLFPGQPFGQ---PPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPP 319 Query: 185 MMDGAMGYVQPPPPPYPGPMEPPVS---GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVY 241 P PP PGP+ PP++ P +P P A A++ P P N Sbjct: 320 --------PGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPP--PTNSG 369 Query: 242 MPTSQ----PPPPPY--YPPEDK 258 MPTS PP PY PP D+ Sbjct: 370 MPTSDSRGPPPTDPYGRPPPYDR 392 Score = 51.6 bits (122), Expect = 7e-07 Identities = 46/135 (34%), Positives = 52/135 (38%), Gaps = 21/135 (15%) Query: 133 ASRGEVPSGAYGYSYMPS---GAYVYPPPVANGMYPCP-PGYPYPPPPPEFYPGPPMMDG 188 +SR P G G P G +P P G P P P PP PP PGPP Sbjct: 192 SSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPP---- 247 Query: 189 AMGYVQPPPPPYPGP-MEPPVSGP----DVPSTPAA-EAKAAEAAASAYYNPGNPHNV-- 240 PP PP PG + PP++GP D P P + PG P V Sbjct: 248 -----GPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG 302 Query: 241 YMPTSQPPPPPYYPP 255 Y P PPPP PP Sbjct: 303 YGPPPGPPPPQQGPP 317 Score = 34.7 bits (78), Expect = 0.086 Identities = 30/81 (37%), Positives = 34/81 (41%), Gaps = 14/81 (17%) Query: 156 PPPVANGMYPCPPGYPYPPPP--PEFYPGPPM--MDGAMGYVQPP------PPPYP-GPM 204 PPP G PPG P P P P F+P P M + PP PPPY G Sbjct: 339 PPPHLPGP---PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDY 395 Query: 205 EPPVSGPDVPSTPAAEAKAAE 225 PP D TP +EA+ E Sbjct: 396 GPPGREMDTARTPLSEAEFEE 416 >gi|150417989 cyclin K isoform 1 [Homo sapiens] Length = 580 Score = 57.8 bits (138), Expect = 1e-08 Identities = 41/143 (28%), Positives = 56/143 (39%), Gaps = 10/143 (6%) Query: 113 TFTAGGAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPY 172 ++ +G + Q M++ S G +P +++P +VYPP PP P Sbjct: 437 SYMSGEGYQSLQSMMKTEGP-SYGALPPAYGPPAHLPYHPHVYPPN--------PPPPPV 487 Query: 173 PPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYY 232 PPPP F P P + GY PPP P PP P + P ++Y Sbjct: 488 PPPPASF-PPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYP 546 Query: 233 NPGNPHNVYMPTSQPPPPPYYPP 255 P P P P PPP PP Sbjct: 547 PPAVPPGGQPPVPPPIPPPGMPP 569 Score = 50.1 bits (118), Expect = 2e-06 Identities = 31/75 (41%), Positives = 35/75 (46%), Gaps = 17/75 (22%) Query: 149 PSGAYVYPPPVANGMYPCPPGY--------PYPPP----PPEFYPGPPMMDGAMGYVQPP 196 P+ Y PPP N +P PP P+PPP PP YP P + G QPP Sbjct: 502 PTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGG----QPP 557 Query: 197 -PPPYPGPMEPPVSG 210 PPP P P PPV G Sbjct: 558 VPPPIPPPGMPPVGG 572 Score = 40.4 bits (93), Expect = 0.002 Identities = 31/113 (27%), Positives = 42/113 (37%), Gaps = 14/113 (12%) Query: 157 PPVANGMYPCPPGYPYPPPPP-------EFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVS 209 P + P PP +P P P E P P+ + VQ PPP +P P+ P Sbjct: 356 PKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPP 415 Query: 210 GPDVPSTPAAEAKAAEAAASAYYNPGNPH---NVYMPTSQPP----PPPYYPP 255 P P P + + ++ Y G + M T P PP Y PP Sbjct: 416 LPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPP 468 Score = 39.3 bits (90), Expect = 0.003 Identities = 39/130 (30%), Positives = 45/130 (34%), Gaps = 35/130 (26%) Query: 156 PPPVANGMYPCPPGYPY--PPPPPEFY-------------------------PGPPMMDG 188 PPP PP P+ PPPPP Y GP G Sbjct: 402 PPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSY--G 459 Query: 189 AMGYVQPPP---PPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTS 245 A+ PP P +P P P VP PA+ A + Y P P Y P + Sbjct: 460 ALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPP--PPPTYNP-N 516 Query: 246 QPPPPPYYPP 255 PPPPP PP Sbjct: 517 FPPPPPRLPP 526 Score = 38.1 bits (87), Expect = 0.008 Identities = 24/66 (36%), Positives = 29/66 (43%), Gaps = 8/66 (12%) Query: 194 QPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYY 253 Q P P P P P V +P E KAAE P P + T+ PP PP + Sbjct: 318 QQPKKPSPQPSSPRQVKRAVVVSPKEENKAAE--------PPPPKIPKIETTHPPLPPAH 369 Query: 254 PPEDKK 259 PP D+K Sbjct: 370 PPPDRK 375 Score = 33.9 bits (76), Expect = 0.15 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 1/81 (1%) Query: 181 PGPPMMDGAMGYVQPPPPPYPGP-MEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHN 239 P PP + P PP +P P +PP++ + P A + P +P Sbjct: 350 PPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAP 409 Query: 240 VYMPTSQPPPPPYYPPEDKKT 260 V+ P P PP PP T Sbjct: 410 VHQPPPLPHRPPPPPPSSYMT 430 >gi|56118221 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein [Homo sapiens] Length = 666 Score = 56.6 bits (135), Expect = 2e-08 Identities = 30/82 (36%), Positives = 37/82 (45%), Gaps = 1/82 (1%) Query: 156 PPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215 PPP+ + P PP + PPP+F P PP + + PPPP P P P PD Sbjct: 560 PPPLDDPELPPPPP-DFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSAR 618 Query: 216 TPAAEAKAAEAAASAYYNPGNP 237 P A AK NPG+P Sbjct: 619 PPPAVAKRPPVPPKRQENPGHP 640 Score = 33.5 bits (75), Expect = 0.19 Identities = 31/114 (27%), Positives = 38/114 (33%), Gaps = 35/114 (30%) Query: 157 PPVANGMYPCPPGYPY------PPPPP-------EFYPGPPMMDGAMGYVQPPPPPY--- 200 P + N P P P+ PPPPP P P+ G P PP Sbjct: 495 PALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFL 554 Query: 201 -PGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYY 253 P P PP+ P++P P + P P PPPPP Y Sbjct: 555 PPPPPPPPLDDPELPPPPPD-----------FMEPP-------PDFVPPPPPSY 590 Score = 28.9 bits (63), Expect = 4.7 Identities = 23/76 (30%), Positives = 25/76 (32%), Gaps = 11/76 (14%) Query: 181 PGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV 240 P P A PPPPP D +PA KA P P + Sbjct: 503 PAVPRAPHAPKSSLPPPPPVR-------RSSDTSGSPATPLKAKGTGGGGL--PAPPDDF 553 Query: 241 YMPTSQPPPPPYYPPE 256 P PPPPP PE Sbjct: 554 LPPP--PPPPPLDDPE 567 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 55.5 bits (132), Expect = 5e-08 Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 13/116 (11%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYP---YPPPPP---EFYPGPPMMDGAMGYVQPPPPPYP 201 +P PPP+ P PP P PPPPP P PP + GA PPPPP P Sbjct: 970 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA---GIPPPPPLP 1026 Query: 202 G---PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 G P PP+ G +P P A G P +P + PPPP P Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1081 Score = 55.5 bits (132), Expect = 5e-08 Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 13/116 (11%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYP---YPPPPP---EFYPGPPMMDGAMGYVQPPPPPYP 201 +P PPP+ P PP P PPPPP P PP + GA PPPPP P Sbjct: 981 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA---GIPPPPPLP 1037 Query: 202 G---PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 G P PP+ G +P P A G P +P + PPPP P Sbjct: 1038 GAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1092 Score = 55.1 bits (131), Expect = 6e-08 Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 13/116 (11%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYP---YPPPPP---EFYPGPPMMDGAMGYVQPPPPPYP 201 +P PPP+ P PP P PPPPP P PP + GA PPPPP P Sbjct: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA---GIPPPPPLP 1092 Query: 202 G---PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 G P PP+ G +P P A G P +P + PPPP P Sbjct: 1093 GAGIPPPPPLPGVGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1147 Score = 54.7 bits (130), Expect = 8e-08 Identities = 38/113 (33%), Positives = 44/113 (38%), Gaps = 7/113 (6%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYP---YPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG-- 202 +P PPP+ P PP P PPPPP G P G PPPPP PG Sbjct: 1058 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG 1117 Query: 203 -PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 P PP+ G +P P A G P +P + PPPP P Sbjct: 1118 IPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP 1169 Score = 53.9 bits (128), Expect = 1e-07 Identities = 39/111 (35%), Positives = 46/111 (41%), Gaps = 8/111 (7%) Query: 151 GAYVYP-PPVANGMYPCPPGYP---YPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG---P 203 GA + P PP+ P PP P PPPPP G P+ G PPPPP PG P Sbjct: 928 GAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIP 987 Query: 204 MEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 PP+ G +P P A G P +P + PPPP P Sbjct: 988 PPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037 Score = 53.1 bits (126), Expect = 2e-07 Identities = 39/116 (33%), Positives = 46/116 (39%), Gaps = 24/116 (20%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYP---YPPPPP---EFYPGPPMMDGAMGYVQPPPPPYP 201 +P PPP+ P PP P PPPPP P PP + GA PPPPP P Sbjct: 1113 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA---GIPPPPPLP 1169 Query: 202 G---PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 G P PP+ G +P P G P +P + PPPP P Sbjct: 1170 GAGIPPPPPLPGVGIPPPPPLP------------GVGIPPPPPLPGAGIPPPPPLP 1213 Score = 52.0 bits (123), Expect = 5e-07 Identities = 36/102 (35%), Positives = 40/102 (39%), Gaps = 14/102 (13%) Query: 156 PPPVANGMYPCPPGYP---YPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG---PMEPPVS 209 PPP+ P PP P PPPPP G P G PPPPP PG P PP+ Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1213 Query: 210 GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251 G +P PA G P +P S PP P Sbjct: 1214 GMGIPPAPAPPLPPP--------GTGIPPPPLLPVSGPPLLP 1247 Score = 49.3 bits (116), Expect = 3e-06 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 9/73 (12%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYP---YPPPPP---EFYPGPPMMDGAMGYVQPPPPPYP 201 +P PPP+ P PP P PPPPP P PP + GA PPPPP P Sbjct: 1157 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGA---GIPPPPPLP 1213 Query: 202 GPMEPPVSGPDVP 214 G PP P +P Sbjct: 1214 GMGIPPAPAPPLP 1226 Score = 47.0 bits (110), Expect = 2e-05 Identities = 38/108 (35%), Positives = 46/108 (42%), Gaps = 6/108 (5%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG-PMEP 206 +PS A PPP+ G PP P PP P P PP + GA G + PP P G P P Sbjct: 891 LPSTAIPQPPPL-QGTEMLPP--PPPPLPGAGIPPPPPLPGA-GILPLPPLPGAGIPPPP 946 Query: 207 PVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 P+ G +P P A G P +P + PPPP P Sbjct: 947 PLPGAAIPPPPPLPG-AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLP 993 Score = 39.3 bits (90), Expect = 0.003 Identities = 40/154 (25%), Positives = 51/154 (33%), Gaps = 49/154 (31%) Query: 146 SYMPSGAYVYPPPVANGMYPCPPGYPYPPPP----PEFY-----------------PGPP 184 S+ P+ + PPP + ++ G P PP EF P PP Sbjct: 800 SHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP 859 Query: 185 MMD--------GAMGYVQPPPPPYPG-----------PMEPPVSG-----PDVPSTPAAE 220 + +G V PPPPP PG P PP+ G P P P A Sbjct: 860 PLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAG 919 Query: 221 AKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 A P P +P + PPPP P Sbjct: 920 IPPPPPLPGAGILPLPP----LPGAGIPPPPPLP 949 Score = 37.4 bits (85), Expect = 0.013 Identities = 25/71 (35%), Positives = 27/71 (38%), Gaps = 9/71 (12%) Query: 156 PPPVANGMYPCPPGYP---YPPPPP------EFYPGPPMMDGAMGYVQPPPPPYPGPMEP 206 PPP+ P PP P PPPPP P PP+ G PP P GP Sbjct: 1187 PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLL 1246 Query: 207 PVSGPDVPSTP 217 P G TP Sbjct: 1247 PQVGSSTLPTP 1257 Score = 35.4 bits (80), Expect = 0.050 Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 9/66 (13%) Query: 151 GAYVYPPPVANGM-YPCPPGYPYPP-----PPPEFYP--GPPMMDGAMGYVQPPPPPYPG 202 GA + PPP GM P P P PP PPP P GPP++ +G P P G Sbjct: 1203 GAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLP-QVGSSTLPTPQVCG 1261 Query: 203 PMEPPV 208 + PP+ Sbjct: 1262 FLPPPL 1267 >gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] Length = 464 Score = 55.1 bits (131), Expect = 6e-08 Identities = 39/109 (35%), Positives = 44/109 (40%), Gaps = 12/109 (11%) Query: 149 PSGAYVYPPPVANGMYPCPP-GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYP-GPMEP 206 P G PPP+ NG+ P PP PPPPP P PPM PP P P GP P Sbjct: 227 PPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPM---------PPTGPAPSGPPGP 277 Query: 207 PVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 P P P A AS + P + P PP P +PP Sbjct: 278 PQLPPPAPGVHPP-APVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPP 325 Score = 45.1 bits (105), Expect = 6e-05 Identities = 42/132 (31%), Positives = 54/132 (40%), Gaps = 15/132 (11%) Query: 136 GEVPSGAYGYSYMPSGAY-VYPP-----PVANGMYPCPPGYPYPPPPPEFYPGPPMMDGA 189 G PSG G +P A V+PP P A+G++P PG PP P +P P + Sbjct: 268 GPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVH--PPAPGVHPPAPGVHPP 325 Query: 190 MGYVQPPP----PPYPGPMEPPVSGPDVPSTPA-AEAKAAEAAASAYYNPGNPH-NVYMP 243 V PP PP PG + PP G P+ A SA +P P + P Sbjct: 326 TSGVHPPAPGVHPPAPG-VHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAP 384 Query: 244 TSQPPPPPYYPP 255 P P +PP Sbjct: 385 AVHPQAPGVHPP 396 Score = 42.4 bits (98), Expect = 4e-04 Identities = 34/108 (31%), Positives = 41/108 (37%), Gaps = 15/108 (13%) Query: 157 PPVANGMYPCPPGYPYPPPPPEFY---PGPPMMDGAMGYVQPPPPP--YPGPMEPPV--- 208 PP + PPG PPPP P PP+ + PPPPP P P PP Sbjct: 217 PPAPPSLPAGPPGVKRPPPPL-MNGLPPRPPLPESL-----PPPPPGGLPLPPMPPTGPA 270 Query: 209 -SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 SGP P A A + P + + P PP P +PP Sbjct: 271 PSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPP 318 Score = 40.0 bits (92), Expect = 0.002 Identities = 40/121 (33%), Positives = 49/121 (40%), Gaps = 24/121 (19%) Query: 149 PSGAYVYPP-----PVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQP------PP 197 P V+PP P A G++P PG +PPP +P P + A V P PP Sbjct: 338 PPAPGVHPPAPGVHPPAPGVHPPAPGV-HPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPP 396 Query: 198 PPYPGPMEPPV--SGPDV-PSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 P P P V P V PS P + +P NP V+ PT P PP P Sbjct: 397 APGMHPQAPGVHPQPPGVHPSAPGVHPQPPGV------HPSNP-GVHPPT--PMPPMLRP 447 Query: 255 P 255 P Sbjct: 448 P 448 Score = 39.7 bits (91), Expect = 0.003 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 20/113 (17%) Query: 149 PSGAYVYPP-----PVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGP 203 P V+PP P A G++P PG PP P +P P + PP PG Sbjct: 317 PPAPGVHPPTSGVHPPAPGVHPPAPGVH--PPAPGVHPPAPGVH----------PPAPGV 364 Query: 204 MEPPVSG--PDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 PP +G P P A A A A + P + P P PP +P Sbjct: 365 HPPPSAGVHPQAPGVHPA-APAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHP 416 Score = 39.3 bits (90), Expect = 0.003 Identities = 36/120 (30%), Positives = 42/120 (35%), Gaps = 20/120 (16%) Query: 149 PSGAYVYPPPVANGMYPC-PPGYP---------YPPPPPEFYPGPPMMDGAMGYVQPPP- 197 P G PP G P PPG P +PP P P + A G P P Sbjct: 255 PPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPG 314 Query: 198 --PPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 PP PG + PP SG P A A + P + P PP P +PP Sbjct: 315 VHPPAPG-VHPPTSGVHPP------APGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPP 367 Score = 34.7 bits (78), Expect = 0.086 Identities = 40/117 (34%), Positives = 46/117 (39%), Gaps = 27/117 (23%) Query: 149 PSGAYVYPPPVANGMYPCPPG-YP-----YPPPPPEFYPGPPMMDGAMGYVQPPP---PP 199 P V+PPP A G++P PG +P +P P P P M A G PP P Sbjct: 359 PPAPGVHPPPSA-GVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPS 417 Query: 200 YPG--PMEPPV--SGPDV-PSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251 PG P P V S P V P TP + PGN PPPPP Sbjct: 418 APGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSE---GPGN---------IPPPPP 462 >gi|25470890 DAZ associated protein 1 isoform a [Homo sapiens] Length = 378 Score = 54.7 bits (130), Expect = 8e-08 Identities = 46/161 (28%), Positives = 61/161 (37%), Gaps = 30/161 (18%) Query: 118 GAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVY---------PPPVANGMYPCPP 168 GA ++G R++ A+ G+ P + Y P G +V PPP G P PP Sbjct: 202 GASQWGSRVVPNAANGWAGQPPP-TWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPP 260 Query: 169 ------------GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPP----YPGPMEPPVSGPD 212 G+P P P+ Y PP + GY PPPPP PG PP + Sbjct: 261 PFTSYIVSTPPGGFPPPQGFPQGYGAPPQF--SFGYGPPPPPPDQFAPPGVPPPPATPGA 318 Query: 213 VPST--PAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251 P P A + + P P+ Y S P PP Sbjct: 319 APLAFPPPPSQAAPDMSKPPTAQPDFPYGQYGLGSYSPAPP 359 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 54.7 bits (130), Expect = 8e-08 Identities = 40/118 (33%), Positives = 49/118 (41%), Gaps = 23/118 (19%) Query: 157 PPVANGMYPCPPGYPYPP--------PPP---EFYPGP-----PMMDGAMGYVQPPPPPY 200 PP A G+ P YPY P PPP + YPGP P GA+ + P PP Sbjct: 985 PPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQ- 1043 Query: 201 PGPMEPPVSGPDVPST----PAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 P PP++ PST P A +SA + +PH V P P P P P Sbjct: 1044 --PPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPP 1099 Score = 43.1 bits (100), Expect = 2e-04 Identities = 37/141 (26%), Positives = 47/141 (33%), Gaps = 32/141 (22%) Query: 139 PSGAYGYSYMPSGAYVYPPPVANGMYPCPP---------GYPYPPPPPEFYPGPPMMDG- 188 P Y Y+ P PPP+ +YP P P+P P P P PP+ G Sbjct: 994 PQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGP 1053 Query: 189 --------------------AMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAA--EA 226 + G P P P P P GP P PAAE Sbjct: 1054 APSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRG 1113 Query: 227 AASAYYNPGNPHNVYMPTSQP 247 AA+A +P + + T P Sbjct: 1114 AAAADLLSSSPESQHGGTQSP 1134 Score = 42.4 bits (98), Expect = 4e-04 Identities = 35/134 (26%), Positives = 52/134 (38%), Gaps = 23/134 (17%) Query: 138 VPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGY----- 192 +P+ + S +P+G +P P P P +P P P F P PP + + Sbjct: 932 IPAQHHFSSGIPAG---FPAPRIG---PQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFP 985 Query: 193 -----VQPPPPPYPGPMEPPVSGPDVPST-------PAAEAKAAEAAASAYYNPGNPHNV 240 + PP PYP +P V G P PA + A + A + +PG P Sbjct: 986 PQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPP 1045 Query: 241 YMPTSQPPPPPYYP 254 + P + P P P Sbjct: 1046 HPPLAYGPAPSTRP 1059 Score = 38.1 bits (87), Expect = 0.008 Identities = 36/127 (28%), Positives = 46/127 (36%), Gaps = 12/127 (9%) Query: 136 GEVPSGAYG---YSYMPSGAYVYPPPVANG--MYPCPPGYPYPPPPPEFYPGPPMMDGAM 190 G +P G Y P + PVA G +YP P P P P ++ Sbjct: 789 GPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPY 848 Query: 191 GYVQPPPPPYPGPMEPP--VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQP- 247 V P PP P PP SGP++ A + A + P H P P Sbjct: 849 VGVGPAPPVAGLPSAPPPQFSGPEL----AMAVRPATTTVDSIQAPIPSHTAPRPNPTPA 904 Query: 248 PPPPYYP 254 PPPP +P Sbjct: 905 PPPPCFP 911 Score = 33.9 bits (76), Expect = 0.15 Identities = 29/112 (25%), Positives = 40/112 (35%), Gaps = 18/112 (16%) Query: 162 GMYPCPPGYPYPPPPPEFYPGPPM----------MDGAMGYV------QPPPPPYPGPME 205 G+ P PP P PP + GP + +D + +P P P P P Sbjct: 850 GVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPC 909 Query: 206 PPVSGPDVPSTPAAEAKAAE--AAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 PV P TP A+ A +++ G P P P P P+ P Sbjct: 910 FPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQP 961 Score = 29.3 bits (64), Expect = 3.6 Identities = 28/105 (26%), Positives = 36/105 (34%), Gaps = 15/105 (14%) Query: 167 PPGYPYPPPPPEFYPGPPMMDGAM------GYVQPPPPPYPGPMEPPVS-GPDVPSTPA- 218 P +P P P PGP + G + G Q P PGP PV+ GP + PA Sbjct: 768 PLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAY 827 Query: 219 -------AEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPE 256 + S+ Y P PPP + PE Sbjct: 828 TPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPE 872 >gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] Length = 638 Score = 53.9 bits (128), Expect = 1e-07 Identities = 49/175 (28%), Positives = 62/175 (35%), Gaps = 60/175 (34%) Query: 141 GAYGYSYMPSGA---YVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGA-------- 189 G + + P+G ++ PPP P PPG+ PPP ++ P+ G Sbjct: 409 GGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468 Query: 190 ------MGYVQPPPPPYPGPMEPPVSGPDVP----------------------------- 214 MG + PPPPP G PP SGP P Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528 Query: 215 -----------STPAAEAKAAEAAAS--AYYNPGNPHNVYMPTS-QPPPPPYYPP 255 S P + + A AAAS A GNP V +P QPP PP PP Sbjct: 529 TTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPP 583 Score = 35.4 bits (80), Expect = 0.050 Identities = 24/53 (45%), Positives = 24/53 (45%), Gaps = 12/53 (22%) Query: 163 MYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215 M P PPG PP PP P PP PPPP G M PP G D PS Sbjct: 566 MVPLPPGV-QPPLPPGAPPPPP----------PPPPGSAGMMIPP-RGGDGPS 606 Score = 34.7 bits (78), Expect = 0.086 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 5/96 (5%) Query: 158 PVANGMYPCPPGYPYPPPP--PEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215 P+A+ P P PPP PP M+ +P + G P GP Sbjct: 339 PLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFP 398 Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251 P +NP P +M QPPPPP Sbjct: 399 HPLPSLTGGHGGHPMQHNPNGPPPPWM---QPPPPP 431 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 53.9 bits (128), Expect = 1e-07 Identities = 49/175 (28%), Positives = 62/175 (35%), Gaps = 60/175 (34%) Query: 141 GAYGYSYMPSGA---YVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGA-------- 189 G + + P+G ++ PPP P PPG+ PPP ++ P+ G Sbjct: 409 GGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468 Query: 190 ------MGYVQPPPPPYPGPMEPPVSGPDVP----------------------------- 214 MG + PPPPP G PP SGP P Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528 Query: 215 -----------STPAAEAKAAEAAAS--AYYNPGNPHNVYMPTS-QPPPPPYYPP 255 S P + + A AAAS A GNP V +P QPP PP PP Sbjct: 529 TTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPP 583 Score = 50.1 bits (118), Expect = 2e-06 Identities = 46/152 (30%), Positives = 59/152 (38%), Gaps = 43/152 (28%) Query: 104 WEGSASYKLTFTAGGAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYPPPVANGM 163 W+ + + T G+I Q+ Q A+ AS G P + +P V PP Sbjct: 525 WQQNTTTTTTSAGTGSIPPWQQQ-QAAAAASPG-APQMQGNPTMVPLPPGVQPP------ 576 Query: 164 YPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEP----PVSGPDVPSTPAA 219 PPG P PPPPP PP G+ G + PPPP P PM+P + G V P Sbjct: 577 --LPPGAPPPPPPP-----PP---GSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPP- 625 Query: 220 EAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251 MP + PPPPP Sbjct: 626 --------------------FGMPPAPPPPPP 637 Score = 34.7 bits (78), Expect = 0.086 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 5/96 (5%) Query: 158 PVANGMYPCPPGYPYPPPP--PEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215 P+A+ P P PPP PP M+ +P + G P GP Sbjct: 339 PLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFP 398 Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251 P +NP P +M QPPPPP Sbjct: 399 HPLPSLTGGHGGHPMQHNPNGPPPPWM---QPPPPP 431 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 53.9 bits (128), Expect = 1e-07 Identities = 37/106 (34%), Positives = 41/106 (38%), Gaps = 15/106 (14%) Query: 149 PSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPV 208 P A V P V P PP +PP PP P PP M PPPPP P P P V Sbjct: 664 PGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAV 723 Query: 209 SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 + P P PA PG P +P P PP +P Sbjct: 724 TVPP-PPLPAP--------------PGVPPPPILPPLPPFPPGLFP 754 Score = 36.6 bits (83), Expect = 0.023 Identities = 31/108 (28%), Positives = 38/108 (35%), Gaps = 18/108 (16%) Query: 157 PPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYP-------------GP 203 PP+ M P P P PPP P P PP P PP P G Sbjct: 1270 PPM---MLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGS 1326 Query: 204 MEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251 + S VP+TP E + S+ + +P P S P P P Sbjct: 1327 LAKSQSTETVPATPGGEPPL--SGGSSGLSLSSPQVPGSPFSYPAPSP 1372 Score = 34.3 bits (77), Expect = 0.11 Identities = 33/124 (26%), Positives = 47/124 (37%), Gaps = 11/124 (8%) Query: 130 ASQASRG--EVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMD 187 A+ A RG ++P GA G + SG P + + + PPP + P P Sbjct: 342 ATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFA------HTPPPAQATPAPGFKS 395 Query: 188 GAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQP 247 Y Q P +P P E P + + + E + A A P P P + P Sbjct: 396 AFSPY-QTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPP--LPPAEPLAKEKPGTPP 452 Query: 248 PPPP 251 PPP Sbjct: 453 GPPP 456 Score = 33.5 bits (75), Expect = 0.19 Identities = 18/38 (47%), Positives = 19/38 (50%), Gaps = 14/38 (36%) Query: 169 GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEP 206 G P PPPP PP QPPPPP P P+EP Sbjct: 1535 GIPAPPPPL-----PP---------QPPPPPPPPPVEP 1558 Score = 33.1 bits (74), Expect = 0.25 Identities = 34/113 (30%), Positives = 40/113 (35%), Gaps = 26/113 (23%) Query: 165 PCPPGYPYP----PPPPEFYPG-----PPMMDGAMGYVQPPPPP---------YPGPMEP 206 P PP P P PPP + PG PP M G + PP PG + Sbjct: 1456 PLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQT 1515 Query: 207 PVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKK 259 PV PST + + P P +P PPPPP P E K Sbjct: 1516 PV----FPSTHDPRTVTLDFRNAGIPAPPPP----LPPQPPPPPPPPPVEPTK 1560 Score = 32.3 bits (72), Expect = 0.43 Identities = 29/100 (29%), Positives = 37/100 (37%), Gaps = 19/100 (19%) Query: 173 PPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPV---------SGPDVPST----PAA 219 P PPPE PGPP G + G P SG D+ + P+A Sbjct: 592 PRPPPE--PGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSA 649 Query: 220 EAKAAEAAASAYYNPGNPH----NVYMPTSQPPPPPYYPP 255 +A+ PG +V PT PPPP +PP Sbjct: 650 PITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPP 689 Score = 30.8 bits (68), Expect = 1.2 Identities = 31/108 (28%), Positives = 36/108 (33%), Gaps = 33/108 (30%) Query: 155 YPPPVANGMYPCPPGYPYP---------------PPPPEFYPGPPMMDGAMGYVQPPPPP 199 Y PVA+ +P PP P P PP P P+ G PPPP Sbjct: 400 YQTPVAH--FPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPP 457 Query: 200 YPGPME---PPVSG-----PDVPSTPAAEAKAAEAAASAYYNPGNPHN 239 ME P G D P TP E+ A P PH+ Sbjct: 458 DTNSMELGGRPTFGWSPEPCDSPGTPTLESSPA--------GPEKPHD 497 Score = 29.3 bits (64), Expect = 3.6 Identities = 16/42 (38%), Positives = 18/42 (42%), Gaps = 3/42 (7%) Query: 156 PPPVANGMYPCPPGYPYPP---PPPEFYPGPPMMDGAMGYVQ 194 PPP + PP P PP PPP P PP G +Q Sbjct: 716 PPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQ 757 Score = 28.5 bits (62), Expect = 6.2 Identities = 29/99 (29%), Positives = 35/99 (35%), Gaps = 12/99 (12%) Query: 165 PCPPGYPYPPP---PPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEA 221 P P G P PPE PG +GAM + P PP PP+S P Sbjct: 1211 PLPVGVEEPADSREPPE-EPGLSQ-EGAM-LLSPEPPAKEVEARPPLSPERAPEHDLEVE 1267 Query: 222 KAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKT 260 P +P +PP PP PPE + T Sbjct: 1268 PEPPMMLPLPLQPP------LPPPRPPRPPSPPPEPETT 1300 Score = 28.1 bits (61), Expect = 8.1 Identities = 13/26 (50%), Positives = 13/26 (50%), Gaps = 6/26 (23%) Query: 156 PPPVANGMYPCPPGYPYPPPPPEFYP 181 PPP P PP P PPPPP P Sbjct: 1539 PPP------PLPPQPPPPPPPPPVEP 1558 >gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo sapiens] Length = 245 Score = 53.9 bits (128), Expect = 1e-07 Identities = 47/167 (28%), Positives = 60/167 (35%), Gaps = 16/167 (9%) Query: 92 IKGTVKAEAGGGWEGSASYKLTFTAGGAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSG 151 + T + GW GS + +A ++ G S G P+G Y S P+G Sbjct: 22 VSNTKPGQPPQGWPGSNPWNNP-SAPSSVPSGLPPSATPSTVPFGPAPTGMYP-SVPPTG 79 Query: 152 AYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMD-GAMGYVQPP-------PPPYPGP 203 PP P PP P PPP YP P + G G P P PY P Sbjct: 80 PPPGPPA------PFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAP 133 Query: 204 MEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP 250 +P +GP P + A Y P P+ P PPPP Sbjct: 134 TDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPP 180 Score = 39.7 bits (91), Expect = 0.003 Identities = 38/122 (31%), Positives = 41/122 (33%), Gaps = 27/122 (22%) Query: 139 PSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPP 198 P G +G M SG + P G YP P PYP P P YP PPP Sbjct: 141 PLGPWGS--MSSGPWA---PGMGGQYPTP-NMPYPSPGP--YP-------------APPP 179 Query: 199 PYPGPMEPPVSGPDV------PSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPY 252 P PPV V P P + Y P NP V S PP P Sbjct: 180 PQAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAPPMPG 239 Query: 253 YP 254 P Sbjct: 240 GP 241 Score = 32.7 bits (73), Expect = 0.33 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Query: 184 PMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVY-- 241 P A+ +P PP P P + P PS+ + + ++ + P P +Y Sbjct: 16 PAKTSAVSNTKPGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVPFGPA-PTGMYPS 74 Query: 242 -MPTSQPP-PPPYYPP 255 PT PP PP +PP Sbjct: 75 VPPTGPPPGPPAPFPP 90 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 53.5 bits (127), Expect = 2e-07 Identities = 38/114 (33%), Positives = 44/114 (38%), Gaps = 12/114 (10%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY--PGPPMMDGAMGYVQPPPPPYPGPME 205 +P G + PPP +G PP PPP PE P P + G G PPPPP PG Sbjct: 624 LPGGTAISPPPPLSGDATIPP----PPPLPEGVGIPSPSSLPG--GTAIPPPPPLPGSAR 677 Query: 206 PPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP----PYYPP 255 P P +P + A P P P PPPP P PP Sbjct: 678 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP 731 Score = 52.0 bits (123), Expect = 5e-07 Identities = 37/112 (33%), Positives = 43/112 (38%), Gaps = 30/112 (26%) Query: 146 SYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG--- 202 S +P G + PPP G PP P P P PP + G G + PPPPP PG Sbjct: 658 SSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG-MPPPPPPLPGGPG 716 Query: 203 -PMEPPV-SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPY 252 P PP GP +P P PG PPPPP+ Sbjct: 717 IPPPPPFPGGPGIPPPP----------------PG--------MGMPPPPPF 744 Score = 48.5 bits (114), Expect = 6e-06 Identities = 32/83 (38%), Positives = 37/83 (44%), Gaps = 15/83 (18%) Query: 148 MPSGAYVYPPPV----ANGMYPCPPGYP----YPPPPPEF-----YPGPPMMDGAMGYVQ 194 +P A + PPP + G+ P PP P PPPPP P PP G G Sbjct: 672 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGI-- 729 Query: 195 PPPPPYPGPMEPPVSGPDVPSTP 217 PPPPP G PP G VP+ P Sbjct: 730 PPPPPGMGMPPPPPFGFGVPAAP 752 Score = 45.1 bits (105), Expect = 6e-05 Identities = 37/117 (31%), Positives = 43/117 (36%), Gaps = 17/117 (14%) Query: 150 SGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPP-- 207 S A + PP P PP P P P PP + PPPPP P P P Sbjct: 557 SAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 616 Query: 208 -VSGPDVPSTPAAEAKAAEAAASAYYN----PGNPHNVYMP--------TSQPPPPP 251 +S P PS P A + S P P V +P T+ PPPPP Sbjct: 617 CISSP--PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 671 Score = 30.4 bits (67), Expect = 1.6 Identities = 20/60 (33%), Positives = 22/60 (36%), Gaps = 20/60 (33%) Query: 195 PPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 PP PP PG SG +P PA PG+ P PPPPP P Sbjct: 574 PPAPPLPGD-----SGTIIPPPPA---------------PGDSTTPPPPPPPPPPPPPLP 613 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 53.5 bits (127), Expect = 2e-07 Identities = 38/114 (33%), Positives = 44/114 (38%), Gaps = 12/114 (10%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFY--PGPPMMDGAMGYVQPPPPPYPGPME 205 +P G + PPP +G PP PPP PE P P + G G PPPPP PG Sbjct: 633 LPGGTAISPPPPLSGDATIPP----PPPLPEGVGIPSPSSLPG--GTAIPPPPPLPGSAR 686 Query: 206 PPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP----PYYPP 255 P P +P + A P P P PPPP P PP Sbjct: 687 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP 740 Score = 52.0 bits (123), Expect = 5e-07 Identities = 37/112 (33%), Positives = 43/112 (38%), Gaps = 30/112 (26%) Query: 146 SYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG--- 202 S +P G + PPP G PP P P P PP + G G + PPPPP PG Sbjct: 667 SSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG-MPPPPPPLPGGPG 725 Query: 203 -PMEPPV-SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPY 252 P PP GP +P P PG PPPPP+ Sbjct: 726 IPPPPPFPGGPGIPPPP----------------PG--------MGMPPPPPF 753 Score = 48.5 bits (114), Expect = 6e-06 Identities = 32/83 (38%), Positives = 37/83 (44%), Gaps = 15/83 (18%) Query: 148 MPSGAYVYPPPV----ANGMYPCPPGYP----YPPPPPEF-----YPGPPMMDGAMGYVQ 194 +P A + PPP + G+ P PP P PPPPP P PP G G Sbjct: 681 LPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGI-- 738 Query: 195 PPPPPYPGPMEPPVSGPDVPSTP 217 PPPPP G PP G VP+ P Sbjct: 739 PPPPPGMGMPPPPPFGFGVPAAP 761 Score = 45.1 bits (105), Expect = 6e-05 Identities = 37/117 (31%), Positives = 43/117 (36%), Gaps = 17/117 (14%) Query: 150 SGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPP-- 207 S A + PP P PP P P P PP + PPPPP P P P Sbjct: 566 SAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 625 Query: 208 -VSGPDVPSTPAAEAKAAEAAASAYYN----PGNPHNVYMP--------TSQPPPPP 251 +S P PS P A + S P P V +P T+ PPPPP Sbjct: 626 CISSP--PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 680 Score = 30.4 bits (67), Expect = 1.6 Identities = 20/60 (33%), Positives = 22/60 (36%), Gaps = 20/60 (33%) Query: 195 PPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 PP PP PG SG +P PA PG+ P PPPPP P Sbjct: 583 PPAPPLPGD-----SGTIIPPPPA---------------PGDSTTPPPPPPPPPPPPPLP 622 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 53.5 bits (127), Expect = 2e-07 Identities = 36/103 (34%), Positives = 40/103 (38%), Gaps = 16/103 (15%) Query: 157 PPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGP---DV 213 P +A P P P PPPP PG P A P PP PG EPP + P D+ Sbjct: 528 PDLAPAAEPAPGAAPPPPPP---LPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDL 584 Query: 214 PSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPE 256 P P PG V P PPPPP PP+ Sbjct: 585 PPPPPPPPPP----------PGTDGPVPPPPPPPPPPPGGPPD 617 Score = 46.6 bits (109), Expect = 2e-05 Identities = 27/67 (40%), Positives = 30/67 (44%), Gaps = 7/67 (10%) Query: 156 PPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215 PPP P P P PPPPP P PP DG + PPPPP PG + D Sbjct: 574 PPPAP----PLPGDLPPPPPPP---PPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSEL 626 Query: 216 TPAAEAK 222 P +AK Sbjct: 627 GPGVKAK 633 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 53.1 bits (126), Expect = 2e-07 Identities = 32/75 (42%), Positives = 33/75 (44%), Gaps = 3/75 (4%) Query: 156 PPPVANGMYPCPPGYPYPPPPP---EFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPD 212 PPP G P G P PPPPP P PP GA G PPPPP P P +GP Sbjct: 352 PPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPA 411 Query: 213 VPSTPAAEAKAAEAA 227 P P A A A Sbjct: 412 PPPLPPALVPAGGLA 426 Score = 48.5 bits (114), Expect = 6e-06 Identities = 33/99 (33%), Positives = 37/99 (37%), Gaps = 21/99 (21%) Query: 171 PYPPPPPEF-----YPGPPMMDGAMGYVQP---------PPPPYPGPMEPPVSGPDVPST 216 P PPPPP P PP++ G G P PPPP P PP G P Sbjct: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPP 371 Query: 217 PAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 P A ++ P P P PPPPP PP Sbjct: 372 PPATGRSGPL-------PPPPPGAGGPPMPPPPPPPPPP 403 Score = 46.6 bits (109), Expect = 2e-05 Identities = 27/61 (44%), Positives = 29/61 (47%), Gaps = 1/61 (1%) Query: 157 PPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPST 216 PPV G+ P PP PPPP P PP A G P PPP PG PP+ P P Sbjct: 343 PPVPLGIAPPPPTPRGPPPPGRGGP-PPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPP 401 Query: 217 P 217 P Sbjct: 402 P 402 Score = 41.2 bits (95), Expect = 0.001 Identities = 36/106 (33%), Positives = 38/106 (35%), Gaps = 37/106 (34%) Query: 157 PPVANG-------MYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVS 209 PP+ G + P P G PPPP P PP G PPPPP P S Sbjct: 329 PPIVGGNKGRSGPLPPVPLGIA-PPPPTPRGPPPPGRGG------PPPPPPPATGR---S 378 Query: 210 GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 GP P P A G P P PPPPP PP Sbjct: 379 GPLPPPPPGA---------------GGP-----PMPPPPPPPPPPP 404 Score = 35.4 bits (80), Expect = 0.050 Identities = 38/121 (31%), Positives = 40/121 (33%), Gaps = 23/121 (19%) Query: 135 RGEVPSGAYGYSYMP------SGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDG 188 RG P G G P SG PPP A G PP P PPPPP G Sbjct: 357 RGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPP-PPPPPSSGNG------ 409 Query: 189 AMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPP 248 P PPP P P P G A PG P + + QPP Sbjct: 410 ------PAPPPLP-PALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSAL---QPP 459 Query: 249 P 249 P Sbjct: 460 P 460 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 52.8 bits (125), Expect = 3e-07 Identities = 41/127 (32%), Positives = 50/127 (39%), Gaps = 16/127 (12%) Query: 145 YSYMPS---GAYVYPPPVANGMYPCPP--GYPYPPPPPEFYP---GPPMMDGAMG----- 191 +S++PS PPP A PP P PP P P P A+ Sbjct: 378 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437 Query: 192 --YVQPPPPPYPGPMEPPVSGPDVPS-TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPP 248 + PP PP P PP S P PS TP ++A + AA P P + M S P Sbjct: 438 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497 Query: 249 PPPYYPP 255 PP PP Sbjct: 498 PPQAPPP 504 Score = 45.4 bits (106), Expect = 5e-05 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%) Query: 165 PCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAA 224 P PP P PPP+ PP + A+ +Q PP P P PP+S PS A A A Sbjct: 382 PSPPLSPLATPPPQ---APPAL--ALPPLQAPPSP---PASPPLSPLATPSPQAPNALAV 433 Query: 225 EAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ 261 + + P +P V P S P PP P +Q Sbjct: 434 HLLQAPFSPPPSPP-VQAPFSPPASPPVSPSATPPSQ 469 Score = 44.3 bits (103), Expect = 1e-04 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 8/107 (7%) Query: 157 PPVANGMYP---CPPGYPYPP--PPPEFYPGPPMMDGAMGYVQPPPPPYPGPME---PPV 208 PPV+ P PP PP PP PPM A Q PPP P++ PP Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517 Query: 209 SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 P +TP +A + A+ P +P + PPP PP Sbjct: 518 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564 Score = 40.4 bits (93), Expect = 0.002 Identities = 29/105 (27%), Positives = 36/105 (34%), Gaps = 5/105 (4%) Query: 156 PPPVANGMYPCPPGYPYPPPPPEF---YPGPPMMDGAMGYVQPPPPPYPGPMEPPV--SG 210 PPP A PP P PP F P P M + PPP P + P+ Sbjct: 515 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 574 Query: 211 PDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 P P++P +A + P PPPPP P Sbjct: 575 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619 Score = 33.9 bits (76), Expect = 0.15 Identities = 33/101 (32%), Positives = 37/101 (36%), Gaps = 16/101 (15%) Query: 167 PPGYPYPPPPPEFYP--GPPMMDGAMGYVQPPP---------PPYPGPMEPPVSGPDVPS 215 PP P PP F P PP+ A Q PP PP P P PP+S P Sbjct: 442 PP--PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPP 498 Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQ--PPPPPYYP 254 A AA A P P + P Q P PP +P Sbjct: 499 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 539 Score = 33.9 bits (76), Expect = 0.15 Identities = 32/105 (30%), Positives = 38/105 (36%), Gaps = 11/105 (10%) Query: 157 PPVANGMYP--CPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPME-----PPVS 209 PPV P PP P PP + PP + V P PP P PM PP + Sbjct: 446 PPVQAPFSPPASPPVSPSATPPSQ---APPSLAAPPLQVPPSPPASP-PMSPSATPPPQA 501 Query: 210 GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 P + + P AK A A P P S P P+ P Sbjct: 502 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 546 Score = 32.7 bits (73), Expect = 0.33 Identities = 36/123 (29%), Positives = 44/123 (35%), Gaps = 28/123 (22%) Query: 133 ASRGEVPSGAYGYSYMPSG-AYVYPPPVAN---------GMYPCP-------PGYPYPPP 175 +S P GY P G A PPP A P P PG P P P Sbjct: 633 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 692 Query: 176 PPEFYPGPPMMDGAMGYVQPPPP----PYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAY 231 P GP DG + P P PG ++P GP P T +A A A ++ Sbjct: 693 PA---TGPGSADGLCTIYETEGPESATPAPGALDP---GPS-PGTSGGKAAAGAGAGASS 745 Query: 232 YNP 234 +P Sbjct: 746 RSP 748 Score = 29.3 bits (64), Expect = 3.6 Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 14/114 (12%) Query: 158 PVANGMYPCPPGYPYPPPPPEFYP------GPPMMDGA--MGYVQPPPPPYPGPMEPPVS 209 P A G P P +P P P PP D A +G + P P P S Sbjct: 257 PSARGT-PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS 315 Query: 210 G--PDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQP-PPPPYYPPEDKKT 260 P +P+TP + + + A P +P P+ Q P PP PP T Sbjct: 316 QAPPTLPATPHSSSLTCQLATPLPLAPPSPS--APPSLQTLPSPPATPPSQATT 367 Score = 29.3 bits (64), Expect = 3.6 Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 17/93 (18%) Query: 148 MPSGAYVYPPPVANGMY--------PCPPGYPY-------PPPPPEFYPGPPMMDGAMGY 192 +P PPP A + P PP P P P P+ P + A+ Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA- 608 Query: 193 VQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAE 225 PPPPP P +SGPD+ ++ E Sbjct: 609 PGPPPPPSRSPSST-LSGPDLAGHSSSATSTPE 640 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 52.8 bits (125), Expect = 3e-07 Identities = 41/127 (32%), Positives = 50/127 (39%), Gaps = 16/127 (12%) Query: 145 YSYMPS---GAYVYPPPVANGMYPCPP--GYPYPPPPPEFYP---GPPMMDGAMG----- 191 +S++PS PPP A PP P PP P P P A+ Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398 Query: 192 --YVQPPPPPYPGPMEPPVSGPDVPS-TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPP 248 + PP PP P PP S P PS TP ++A + AA P P + M S P Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458 Query: 249 PPPYYPP 255 PP PP Sbjct: 459 PPQAPPP 465 Score = 45.4 bits (106), Expect = 5e-05 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 9/97 (9%) Query: 165 PCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAA 224 P PP P PPP+ PP + A+ +Q PP P P PP+S PS A A A Sbjct: 343 PSPPLSPLATPPPQ---APPAL--ALPPLQAPPSP---PASPPLSPLATPSPQAPNALAV 394 Query: 225 EAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ 261 + + P +P V P S P PP P +Q Sbjct: 395 HLLQAPFSPPPSPP-VQAPFSPPASPPVSPSATPPSQ 430 Score = 44.3 bits (103), Expect = 1e-04 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 8/107 (7%) Query: 157 PPVANGMYP---CPPGYPYPP--PPPEFYPGPPMMDGAMGYVQPPPPPYPGPME---PPV 208 PPV+ P PP PP PP PPM A Q PPP P++ PP Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478 Query: 209 SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 P +TP +A + A+ P +P + PPP PP Sbjct: 479 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 525 Score = 40.4 bits (93), Expect = 0.002 Identities = 29/105 (27%), Positives = 36/105 (34%), Gaps = 5/105 (4%) Query: 156 PPPVANGMYPCPPGYPYPPPPPEF---YPGPPMMDGAMGYVQPPPPPYPGPMEPPV--SG 210 PPP A PP P PP F P P M + PPP P + P+ Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535 Query: 211 PDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 P P++P +A + P PPPPP P Sbjct: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580 Score = 33.9 bits (76), Expect = 0.15 Identities = 33/101 (32%), Positives = 37/101 (36%), Gaps = 16/101 (15%) Query: 167 PPGYPYPPPPPEFYP--GPPMMDGAMGYVQPPP---------PPYPGPMEPPVSGPDVPS 215 PP P PP F P PP+ A Q PP PP P P PP+S P Sbjct: 403 PP--PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPP 459 Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQ--PPPPPYYP 254 A AA A P P + P Q P PP +P Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 500 Score = 33.9 bits (76), Expect = 0.15 Identities = 32/105 (30%), Positives = 38/105 (36%), Gaps = 11/105 (10%) Query: 157 PPVANGMYP--CPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPME-----PPVS 209 PPV P PP P PP + PP + V P PP P PM PP + Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQ---APPSLAAPPLQVPPSPPASP-PMSPSATPPPQA 462 Query: 210 GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 P + + P AK A A P P S P P+ P Sbjct: 463 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 507 Score = 32.7 bits (73), Expect = 0.33 Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 10/79 (12%) Query: 165 PCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG--------PMEPPVSGPDVPST 216 P PPG P PPPP P + GA G V P P P +GP S Sbjct: 27 PRPPGSPRPPPP--VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSR 84 Query: 217 PAAEAKAAEAAASAYYNPG 235 P A + A + +PG Sbjct: 85 PPASGRGERAPPAKNTSPG 103 Score = 32.7 bits (73), Expect = 0.33 Identities = 36/123 (29%), Positives = 44/123 (35%), Gaps = 28/123 (22%) Query: 133 ASRGEVPSGAYGYSYMPSG-AYVYPPPVAN---------GMYPCP-------PGYPYPPP 175 +S P GY P G A PPP A P P PG P P P Sbjct: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 653 Query: 176 PPEFYPGPPMMDGAMGYVQPPPP----PYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAY 231 P GP DG + P P PG ++P GP P T +A A A ++ Sbjct: 654 PA---TGPGSADGLCTIYETEGPESATPAPGALDP---GPS-PGTSGGKAAAGAGAGASS 706 Query: 232 YNP 234 +P Sbjct: 707 RSP 709 Score = 31.2 bits (69), Expect = 0.95 Identities = 37/165 (22%), Positives = 60/165 (36%), Gaps = 23/165 (13%) Query: 97 KAEAGGGWEGSASYKLTFTAGGAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVYP 156 + AGGG + AS L+ +A + + ++RG + A+ P G Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPAR-----SGPSARGTPRAPAHPSQPKPKGLQALR 272 Query: 157 PPVANGMYPCPPGYPYPPPPPEFYPG-PPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPS 215 PP PP + P P+ + P PP P + P P+ Sbjct: 273 PPQVT------------PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320 Query: 216 TPAAEAKAAEAA----ASAYYNPGNPHN-VYMPTSQPPPPPYYPP 255 TP ++A + + A+ + P P + + P Q PP PP Sbjct: 321 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365 Score = 29.3 bits (64), Expect = 3.6 Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 17/93 (18%) Query: 148 MPSGAYVYPPPVANGMY--------PCPPGYPY-------PPPPPEFYPGPPMMDGAMGY 192 +P PPP A + P PP P P P P+ P + A+ Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA- 569 Query: 193 VQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAE 225 PPPPP P +SGPD+ ++ E Sbjct: 570 PGPPPPPSRSPSST-LSGPDLAGHSSSATSTPE 601 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 52.4 bits (124), Expect = 4e-07 Identities = 35/108 (32%), Positives = 42/108 (38%), Gaps = 8/108 (7%) Query: 156 PPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMG-------YVQPPPPPYPGPMEPPV 208 PP +A PP P PP P A+ + PP PP P PP Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681 Query: 209 SGPDVPS-TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 S P PS TP ++A + AA P P + M S PPP PP Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729 Score = 47.4 bits (111), Expect = 1e-05 Identities = 39/114 (34%), Positives = 48/114 (42%), Gaps = 17/114 (14%) Query: 156 PPPVANGMYPCPP--GYPYPP------PPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPP 207 PPP A PP G P PP PPP+ PP + A+ +Q PP P P PP Sbjct: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQ---APPXL--ALPPLQAPPSP---PASPP 641 Query: 208 VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ 261 +S PS A A A + + P +P V P S P PP P +Q Sbjct: 642 LSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPSATPPSQ 694 Score = 43.9 bits (102), Expect = 1e-04 Identities = 38/108 (35%), Positives = 45/108 (41%), Gaps = 13/108 (12%) Query: 157 PPVANGMYP---CPPGYPYPP--PPPEFYPGPPMMDGAMGYVQPPPPPYPGPME----PP 207 PPV+ P PP PP PP PPM A Q PPP P++ PP Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP 742 Query: 208 VSGPDVPS-TPAAEAKAAEAAASAYYNPGNPHNVYM-PTSQPPP--PP 251 S P PS TP AA P P ++ M P ++PPP PP Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790 Score = 43.1 bits (100), Expect = 2e-04 Identities = 35/95 (36%), Positives = 38/95 (40%), Gaps = 9/95 (9%) Query: 167 PPGYPYPPPPPEFYP--GPPMMDGAMGYVQPPP----PPYPGPMEPPVSGPDVPS-TPAA 219 PP P PP F P PP+ A Q PP PP P PP S P PS TP Sbjct: 667 PP--PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724 Query: 220 EAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 +A AA P P + M S PPP P Sbjct: 725 QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759 Score = 42.0 bits (97), Expect = 5e-04 Identities = 30/113 (26%), Positives = 38/113 (33%), Gaps = 5/113 (4%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPPPPEF---YPGPPMMDGAMGYVQPPPPPYPGPM 204 +P PPP A PP P PP F P P M + PPP P + Sbjct: 776 LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835 Query: 205 EPPV--SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 P+ P P++P +A + P PPPPP P Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888 Score = 40.8 bits (94), Expect = 0.001 Identities = 32/104 (30%), Positives = 39/104 (37%), Gaps = 7/104 (6%) Query: 149 PSGAYVYP-PPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPP 207 PSG P PP N P P P PP P P A +Q P P P PP Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP---PATPP 365 Query: 208 VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPP 251 P +TP +A + PH++ P+ Q PP P Sbjct: 366 SQAPPSMTTPPMQAPPSLQTIPPIQ---VPHSLTSPSLQAPPSP 406 Score = 40.4 bits (93), Expect = 0.002 Identities = 29/93 (31%), Positives = 35/93 (37%), Gaps = 15/93 (16%) Query: 165 PCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSG-PDVPSTPAAEAKA 223 PCP P PP PP ++ PPP P PP+ G P P +P A Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIA--TPPPQAPPALASPPLQGLPSPPLSPLATPP- 618 Query: 224 AEAAASAYYNPGNPHNVYMPTSQ-PPPPPYYPP 255 P P + +P Q PP PP PP Sbjct: 619 ----------PQAPPXLALPPLQAPPSPPASPP 641 Score = 40.0 bits (92), Expect = 0.002 Identities = 38/123 (30%), Positives = 45/123 (36%), Gaps = 20/123 (16%) Query: 149 PSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPP----PPYPGPM 204 P PPP A PP PP PP PPM A + PP PP P Sbjct: 715 PMSPSATPPPQAPPPLAAPP-LQVPPSPPA---SPPMSPSATPPPRVPPLLAAPPLQVPP 770 Query: 205 EPPVSGPDVP-STPAAEAKAAEAAASAYYNPGNPHNV-----YMPTSQPP------PPPY 252 PP S P P + P +A A A P P + + P++ P PPP Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830 Query: 253 YPP 255 PP Sbjct: 831 APP 833 Score = 39.3 bits (90), Expect = 0.003 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 19/114 (16%) Query: 157 PPVANGMYPCPPGYPYPP-----PPPEFYPG--PPMMDGAMG-----YVQPPPPPYPGPM 204 PP+ PP PP PP E P PP + A +++ PP P P P+ Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569 Query: 205 EPPVS-----GPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPP--PP 251 + P S P+ PS+ A A A ++ G P P + PPP PP Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623 Score = 32.7 bits (73), Expect = 0.33 Identities = 36/123 (29%), Positives = 44/123 (35%), Gaps = 28/123 (22%) Query: 133 ASRGEVPSGAYGYSYMPSG-AYVYPPPVAN---------GMYPCP-------PGYPYPPP 175 +S P GY P G A PPP A P P PG P P P Sbjct: 902 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 961 Query: 176 PPEFYPGPPMMDGAMGYVQPPPP----PYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAY 231 P GP DG + P P PG ++P GP P T +A A A ++ Sbjct: 962 PA---TGPGSADGLCTIYETEGPESATPAPGALDP---GPS-PGTSGGKAAAGAGAGASS 1014 Query: 232 YNP 234 +P Sbjct: 1015 RSP 1017 Score = 29.3 bits (64), Expect = 3.6 Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 17/93 (18%) Query: 148 MPSGAYVYPPPVANGMY--------PCPPGYPY-------PPPPPEFYPGPPMMDGAMGY 192 +P PPP A + P PP P P P P+ P + A+ Sbjct: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA- 877 Query: 193 VQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAE 225 PPPPP P +SGPD+ ++ E Sbjct: 878 PGPPPPPSRSPSST-LSGPDLAGHSSSATSTPE 909 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 52.4 bits (124), Expect = 4e-07 Identities = 36/104 (34%), Positives = 42/104 (40%), Gaps = 23/104 (22%) Query: 171 PYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVS-----------------GPD- 212 P+ PPP P P M G G QPPPPP P P P +S GP Sbjct: 78 PHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPG 137 Query: 213 -VPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 VP + ++ +Y P YMP Q PPP YYPP Sbjct: 138 LVPMELESPPESPPVPPGSYMPPSQS---YMPPPQ-PPPSYYPP 177 Score = 45.4 bits (106), Expect = 5e-05 Identities = 35/123 (28%), Positives = 51/123 (41%), Gaps = 32/123 (26%) Query: 157 PPVANGMYPCPPGYPY---PPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDV 213 PPV G Y PP Y P PPP +YP + Y+ PP P P + P S + Sbjct: 150 PPVPPGSY-MPPSQSYMPPPQPPPSYYP----PTSSQPYL---PPAQPSPSQSPPSQSYL 201 Query: 214 PSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQ----------------PPPPPYYPPED 257 TP+ + ++ + + ++ Y+P+SQ PPPP PP + Sbjct: 202 APTPSYSSSSSSSQSYLSHSQS-----YLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGN 256 Query: 258 KKT 260 K T Sbjct: 257 KTT 259 Score = 42.7 bits (99), Expect = 3e-04 Identities = 40/129 (31%), Positives = 46/129 (35%), Gaps = 30/129 (23%) Query: 156 PPPVANGMYPC---PPGYP-----------YPPP------PPEFYPGPPMMDGAMGYVQP 195 PPPV P PPG P PPP PP P P + A V P Sbjct: 561 PPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMP 620 Query: 196 PPP-----PYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPT----SQ 246 PP P PG P V P AA A ++ S+ P P +PT Sbjct: 621 LPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQV-PEKPRPALLPTPVSFGS 679 Query: 247 PPPPPYYPP 255 PP Y+PP Sbjct: 680 APPTTYHPP 688 Score = 39.3 bits (90), Expect = 0.003 Identities = 26/62 (41%), Positives = 27/62 (43%), Gaps = 13/62 (20%) Query: 162 GMYPCPPGYPYPPPPPEFYPG-------PPMMDGAMGY-----VQPPPPPYPGPMEPPVS 209 GMYP PPG PPPP PG PP + PPPPP P P PPV Sbjct: 1504 GMYP-PPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVI 1562 Query: 210 GP 211 P Sbjct: 1563 KP 1564 Score = 38.1 bits (87), Expect = 0.008 Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 15/103 (14%) Query: 156 PPPVANGMYPCPPGYPYPPPP--PEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDV 213 PPP PP P PPP P P PP+M A+ PPP M PPV P + Sbjct: 517 PPPFVP-YSQMPPPLPTMPPPVLPPSLP-PPVMPPALPATVPPP-----GMPPPVMPPSL 569 Query: 214 PSTPAAEAKAAEAAASAYYNPGNPHNVYMPT-SQPPPPPYYPP 255 P++ +++ G P + P+ S PPP PP Sbjct: 570 PTSVPPPGMPPSLSSA-----GPPPVLPPPSLSSAGPPPVLPP 607 Score = 36.2 bits (82), Expect = 0.030 Identities = 31/111 (27%), Positives = 40/111 (36%), Gaps = 14/111 (12%) Query: 145 YSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPM 204 YS MP PPPV P P PP P P P M PPP P + Sbjct: 523 YSQMPPPLPTMPPPVLPPSLPPPV---MPPALPATVPPPGM----------PPPVMPPSL 569 Query: 205 EPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPT-SQPPPPPYYP 254 V P +P + ++ + + G P + P+ S PPP P Sbjct: 570 PTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMP 620 Score = 34.3 bits (77), Expect = 0.11 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 15/62 (24%) Query: 149 PSGAYVYP--PPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEP 206 P G+ V P PP + + P P PPPPP PP+ PPPPP P Sbjct: 1521 PPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP----PPL---------PPPPPVIKPQTS 1567 Query: 207 PV 208 V Sbjct: 1568 AV 1569 Score = 32.7 bits (73), Expect = 0.33 Identities = 26/86 (30%), Positives = 30/86 (34%), Gaps = 19/86 (22%) Query: 180 YPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAA----------EAKAAEAAAS 229 YP PP+ PPPPP P P G +TPAA E A+ Sbjct: 14 YPPPPV---------PPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQL 64 Query: 230 AYYNPGNPHNVYMPTSQPPPPPYYPP 255 + V P PPPP PP Sbjct: 65 QQMHQKQMQCVLQPHHLPPPPLPPPP 90 Score = 29.3 bits (64), Expect = 3.6 Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 2/61 (3%) Query: 201 PGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKT 260 PG + PV D P P E A + +P + P ++ PPP PPE+ ++ Sbjct: 314 PGHKKGPVVAKDTPE-PVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPP-LPPEEPQS 371 Query: 261 Q 261 + Sbjct: 372 E 372 >gi|41281808 harmonin isoform b3 [Homo sapiens] Length = 899 Score = 52.0 bits (123), Expect = 5e-07 Identities = 36/130 (27%), Positives = 53/130 (40%), Gaps = 23/130 (17%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPP--PPEFYPGPPMMD-------GAMGYVQPPPP 198 +P + YPP + + P P+PPP PP P PP++ + +VQ PP Sbjct: 546 IPLDMFYYPPKTPSAL----PVMPHPPPSNPPHKVPAPPVLPLSGHVSASSSPWVQRTPP 601 Query: 199 PYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVY----------MPTSQPP 248 P P P P V D+ T + EA ++ + G+ N PT+ P Sbjct: 602 PIPIPPPPSVPTQDLTPTRPLPSALEEALSNHPFRTGDTGNPVEDWEAKNHSGKPTNSPV 661 Query: 249 PPPYYPPEDK 258 P +PP K Sbjct: 662 PEQSFPPTPK 671 Score = 28.9 bits (63), Expect = 4.7 Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 11/65 (16%) Query: 195 PPPPPYPGPMEPPV----SGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP 250 PPPPP P+ PP+ G + +T + YY P P + + P PP Sbjct: 516 PPPPPSVSPLAPPLRRFAGGLHLHTTDLDDI----PLDMFYYPPKTPSALPV---MPHPP 568 Query: 251 PYYPP 255 P PP Sbjct: 569 PSNPP 573 >gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens] Length = 407 Score = 52.0 bits (123), Expect = 5e-07 Identities = 46/154 (29%), Positives = 59/154 (38%), Gaps = 31/154 (20%) Query: 118 GAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAYVY---------PPPVANGMYPCPP 168 GA ++G R++ A+ G+ P + Y P G +V PPP G P PP Sbjct: 202 GASQWGSRVVPNAANGWAGQPPP-TWQQGYGPQGMWVPAGQAIGGYGPPPAGRGAPPPPP 260 Query: 169 ------------GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPST 216 G+P P P+ Y PP + GY PPPPP P P P+T Sbjct: 261 PFTSYIVSTPPGGFPPPQGFPQGYGAPPQF--SFGYGPPPPPP---DQFAPPGVPPPPAT 315 Query: 217 PAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP 250 P A A S P PT+QP P Sbjct: 316 PGAAPLAFPPPPS----QAAPDMSKPPTAQPDFP 345 Score = 32.0 bits (71), Expect = 0.56 Identities = 27/102 (26%), Positives = 30/102 (29%), Gaps = 34/102 (33%) Query: 144 GYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYP---GPPMMDGAMGYVQPP---- 196 GY P ++ Y PP PPG P PP P P PP A +PP Sbjct: 283 GYGAPPQFSFGYGPPPPPPDQFAPPGVPPPPATPGAAPLAFPPPPSQAAPDMSKPPTAQP 342 Query: 197 ---------------------------PPPYPGPMEPPVSGP 211 PP Y GP P GP Sbjct: 343 DFPYGQYAGYGQDLSGFGQGFSDPSQQPPSYGGPSVPGSGGP 384 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 51.6 bits (122), Expect = 7e-07 Identities = 38/105 (36%), Positives = 42/105 (40%), Gaps = 15/105 (14%) Query: 165 PCPP--GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPY---------PGPMEPPVSGPDV 213 P PP G P PPPPP GPP A G PPPPP P P P V+ P Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPP-PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPP 337 Query: 214 PSTPAAEAKAAEAAASAYYNPGNPHNVYM---PTSQPPPPPYYPP 255 P +SA P P + P + PPPPP PP Sbjct: 338 PPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPP 382 Score = 51.2 bits (121), Expect = 9e-07 Identities = 39/111 (35%), Positives = 43/111 (38%), Gaps = 14/111 (12%) Query: 156 PPPVANGMYPCPPGYPY---PPPPPEFYPG-PPMMDGAMGYVQPPPPPYPGPMEPPVSGP 211 PPP + G P PP P+ PPPPP G PP PPPPP P P V+ P Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPP---PSRPSVAVP 335 Query: 212 DVPSTPAAEAKAAEAAASAYYNPGNPHN-------VYMPTSQPPPPPYYPP 255 P +SA P P V P PPPPP PP Sbjct: 336 PPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPP 386 Score = 50.4 bits (119), Expect = 2e-06 Identities = 30/65 (46%), Positives = 33/65 (50%), Gaps = 11/65 (16%) Query: 156 PPPVANGMYPCPP-----GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSG 210 PPP N MYP PP P PPPP PP + G +G V PPPPP P P P Sbjct: 335 PPPPPNRMYPPPPPALPSSAPSGPPPP-----PPSVLG-VGPVAPPPPPPPPPPPGPPPP 388 Query: 211 PDVPS 215 P +PS Sbjct: 389 PGLPS 393 Score = 49.7 bits (117), Expect = 3e-06 Identities = 38/109 (34%), Positives = 40/109 (36%), Gaps = 13/109 (11%) Query: 156 PPPVANGMYPCPP--GYPYPPPPPEFYPG---PPMMDGAMGYVQPPPPP---YPGPMEPP 207 PPP N P PP G PPPPP P PP PPPPP YP P PP Sbjct: 291 PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPP--PP 348 Query: 208 VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPE 256 PS P + P P P PPPPP P + Sbjct: 349 ALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP---PPPGPPPPPGLPSD 394 Score = 48.1 bits (113), Expect = 8e-06 Identities = 31/90 (34%), Positives = 35/90 (38%), Gaps = 21/90 (23%) Query: 171 PYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAA------ 224 P PPPP P PP PPPP GP PP G P P + A A Sbjct: 277 PPPPPPSRGGPPPP----------PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPP 326 Query: 225 EAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 + S P P+ +Y PPPPP P Sbjct: 327 PSRPSVAVPPPPPNRMY-----PPPPPALP 351 Score = 40.8 bits (94), Expect = 0.001 Identities = 30/81 (37%), Positives = 31/81 (38%), Gaps = 21/81 (25%) Query: 149 PSGAYVYPPPVANGMYPCPPGYPY----PPPPPEFYPGPP--MMDGAMGYVQPPPP---- 198 PS A PP P PP P PPPP YP PP + A PPPP Sbjct: 314 PSRAPTAAPP------PPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLG 367 Query: 199 -----PYPGPMEPPVSGPDVP 214 P P P PP GP P Sbjct: 368 VGPVAPPPPPPPPPPPGPPPP 388 Score = 36.6 bits (83), Expect = 0.023 Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 11/54 (20%) Query: 148 MPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYP 201 +PS A PPP + P P PPPPP PGP PPPP P Sbjct: 350 LPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGP-----------PPPPGLP 392 Score = 29.3 bits (64), Expect = 3.6 Identities = 18/38 (47%), Positives = 18/38 (47%), Gaps = 6/38 (15%) Query: 146 SYMPSGAYVYPP------PVANGMYPCPPGYPYPPPPP 177 S PSG PP PVA P PP P PPPPP Sbjct: 352 SSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPP 389 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 51.6 bits (122), Expect = 7e-07 Identities = 39/121 (32%), Positives = 44/121 (36%), Gaps = 11/121 (9%) Query: 136 GEVPSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQP 195 G S S+ P + PP + PP P PPPP P PP G P Sbjct: 288 GPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTP 347 Query: 196 PPPPYPG-PMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYP 254 PPP P P P + P P P A A Y P + PT PPPP P Sbjct: 348 PPPSPPSFPPHPDFAAPPPPPPPPA----------ADYPTLPPPPLSQPTGGAPPPPPPP 397 Query: 255 P 255 P Sbjct: 398 P 398 Score = 50.8 bits (120), Expect = 1e-06 Identities = 37/116 (31%), Positives = 43/116 (37%), Gaps = 34/116 (29%) Query: 147 YMPSGAYVYPPPVANGMYPCPP-------GYPYPPPPPEFYPGPPMMDGAMGYVQPPPPP 199 + P A PPP G+ P PP G P PP PP F P P + PPPPP Sbjct: 316 FAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD-------FAAPPPPP 368 Query: 200 YPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 P P P +P P ++ P P PPPPP PP Sbjct: 369 PP----PAADYPTLPPPPLSQ----------------PTGGAPPPPPPPPPPGPPP 404 Score = 48.5 bits (114), Expect = 6e-06 Identities = 27/65 (41%), Positives = 32/65 (49%), Gaps = 8/65 (12%) Query: 156 PPPVANGMYPCPPGYPYPPPPPE----FYPG--PPMMDGAMGYVQPPPP--PYPGPMEPP 207 PPP + +P P + PPPPP YP PP + G PPPP P PGP PP Sbjct: 347 PPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP 406 Query: 208 VSGPD 212 +G D Sbjct: 407 FTGAD 411 Score = 44.7 bits (104), Expect = 8e-05 Identities = 39/110 (35%), Positives = 45/110 (40%), Gaps = 35/110 (31%) Query: 155 YPPPVAN-GMYPCP-PGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPP--YPGPMEPPVSG 210 +PPP G P P PG+ PP PP P PP M G + PPPPP + P PP Sbjct: 299 HPPPAPPLGSPPGPKPGFAPPPAPP---PPPPPMIG----IPPPPPPVGFGSPGTPPPPS 351 Query: 211 PDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKT 260 P PS P PH + + PPPPP P D T Sbjct: 352 P--PSFP-------------------PHPDF---AAPPPPPPPPAADYPT 377 Score = 39.3 bits (90), Expect = 0.003 Identities = 31/111 (27%), Positives = 42/111 (37%), Gaps = 8/111 (7%) Query: 151 GAYVYPPPVA--NGMYPCPPGYP---YPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPME 205 G YPP + NG C YPPPP P + + PPP + P++ Sbjct: 220 GTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVD 279 Query: 206 -PPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 SG P + + + A +P P + P PPPPP PP Sbjct: 280 NQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPP--PP 328 Score = 38.1 bits (87), Expect = 0.008 Identities = 30/90 (33%), Positives = 35/90 (38%), Gaps = 11/90 (12%) Query: 146 SYMPSGAYVYPPPVANGMYPCPPGYPYP--PPPPEFYP--GPPMMDGAMGYVQPPPPPYP 201 S+ P + PPP P PP YP PPPP P G P PPPPP+ Sbjct: 354 SFPPHPDFAAPPPP-----PPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFT 408 Query: 202 GPMEPPVSGPDVPST--PAAEAKAAEAAAS 229 G P P + T P + A A S Sbjct: 409 GADGQPAIPPPLSDTTKPKSSLPAVSDARS 438 Score = 37.7 bits (86), Expect = 0.010 Identities = 29/76 (38%), Positives = 33/76 (43%), Gaps = 12/76 (15%) Query: 139 PSGAYGYSYMPSGAYVYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPP-P 197 P A Y +P PPP++ PP PPPPP P PP GA G QP P Sbjct: 369 PPPAADYPTLP------PPPLSQPTGGAPPP---PPPPPPPGPPPPPFTGADG--QPAIP 417 Query: 198 PPYPGPMEPPVSGPDV 213 PP +P S P V Sbjct: 418 PPLSDTTKPKSSLPAV 433 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 51.2 bits (121), Expect = 9e-07 Identities = 28/70 (40%), Positives = 31/70 (44%), Gaps = 16/70 (22%) Query: 156 PPPVANG------MYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVS 209 PPP+ G P PPG P PPP P P PP PPPPP P + PP Sbjct: 316 PPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP----------PPPPPLPNQVPPPPP 365 Query: 210 GPDVPSTPAA 219 P P PA+ Sbjct: 366 PPPAPPLPAS 375 Score = 46.2 bits (108), Expect = 3e-05 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 24/83 (28%) Query: 173 PPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYY 232 PPPPP PGP A+ PPPP P P P +GP P P Sbjct: 313 PPPPPPLPPGPAQASVAL----PPPPGPPPPPPLPSTGPPPPPPP--------------- 353 Query: 233 NPGNPHNVYMPTSQPPPPPYYPP 255 P P+ V PPPPP PP Sbjct: 354 -PPLPNQV----PPPPPPPPAPP 371 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 51.2 bits (121), Expect = 9e-07 Identities = 28/70 (40%), Positives = 31/70 (44%), Gaps = 16/70 (22%) Query: 156 PPPVANG------MYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVS 209 PPP+ G P PPG P PPP P P PP PPPPP P + PP Sbjct: 316 PPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP----------PPPPPLPNQVPPPPP 365 Query: 210 GPDVPSTPAA 219 P P PA+ Sbjct: 366 PPPAPPLPAS 375 Score = 46.2 bits (108), Expect = 3e-05 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 24/83 (28%) Query: 173 PPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPDVPSTPAAEAKAAEAAASAYY 232 PPPPP PGP A+ PPPP P P P +GP P P Sbjct: 313 PPPPPPLPPGPAQASVAL----PPPPGPPPPPPLPSTGPPPPPPP--------------- 353 Query: 233 NPGNPHNVYMPTSQPPPPPYYPP 255 P P+ V PPPPP PP Sbjct: 354 -PPLPNQV----PPPPPPPPAPP 371 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 50.8 bits (120), Expect = 1e-06 Identities = 44/131 (33%), Positives = 46/131 (35%), Gaps = 24/131 (18%) Query: 149 PSGAYVYPPPVANG--MYPCPPGYPYPPPP-------PEFYPGPPMMDGAMGYVQPP-PP 198 P G PPP P PPG P PPP P PG P G QP PP Sbjct: 53 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 112 Query: 199 PYPG-PMEPP------VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV-----YMPTSQ 246 P PG P PP GP P P + + S PG P P Sbjct: 113 PPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 172 Query: 247 PPPP--PYYPP 255 PPPP P PP Sbjct: 173 PPPPGKPQGPP 183 Score = 49.3 bits (116), Expect = 3e-06 Identities = 42/131 (32%), Positives = 45/131 (34%), Gaps = 24/131 (18%) Query: 149 PSGAYVYPPPVANG--MYPCPPGYPYPPPP-------PEFYPGPPMMDGAMGYVQ---PP 196 P G PPP P PPG P PPP P PG P G Q PP Sbjct: 114 PPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 173 Query: 197 PPPYPGPMEPP-----VSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNV-----YMPTSQ 246 PPP PP GP P P + + S+ PG P P Sbjct: 174 PPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP 233 Query: 247 PPPP--PYYPP 255 PPPP P PP Sbjct: 234 PPPPGKPQGPP 244 Score = 41.2 bits (95), Expect = 0.001 Identities = 30/101 (29%), Positives = 35/101 (34%), Gaps = 6/101 (5%) Query: 156 PPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG-PMEPPVSGPDVP 214 PP G P P PPPP PG P G +P PP PG P PP G Sbjct: 215 PPGKPQGPPPQGGNQPQGPPPP---PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGS-- 269 Query: 215 STPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPP 255 + +A + + NP P P P PP Sbjct: 270 KSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 310 Score = 38.9 bits (89), Expect = 0.005 Identities = 36/127 (28%), Positives = 42/127 (33%), Gaps = 32/127 (25%) Query: 146 SYMPSGAYVYPPPVANGMY---PCPPGYPY------------PPPPPEFYPGPPMMDGAM 190 S P G PPP P PPG P PPPP + GPP G+ Sbjct: 212 SQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPAQGGSK 270 Query: 191 GYVQPPPPPYP-GPMEPPVSGPDVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPP 249 PP P GP + + P P PA GNP P + P Sbjct: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAG---------------GNPQQPQAPPAGQPQ 315 Query: 250 PPYYPPE 256 P PP+ Sbjct: 316 GPPRPPQ 322 Score = 37.7 bits (86), Expect = 0.010 Identities = 33/102 (32%), Positives = 37/102 (36%), Gaps = 21/102 (20%) Query: 161 NGMYPCPPG--YPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPG-PMEPPVSGPD--VPS 215 N P P G P PPPP PG P G +P PP PG P PP G P Sbjct: 35 NPQGPSPQGGNKPQGPPPP---PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 91 Query: 216 TPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPP--PYYPP 255 +P + + P P PPPP P PP Sbjct: 92 SPPGKPQGPP-----------PQGGNQPQGPPPPPGKPQGPP 122 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.135 0.426 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,489,330 Number of Sequences: 37866 Number of extensions: 1281988 Number of successful extensions: 23442 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 651 Number of HSP's successfully gapped in prelim test: 1044 Number of HSP's that attempted gapping in prelim test: 7127 Number of HSP's gapped (non-prelim): 8619 length of query: 261 length of database: 18,247,518 effective HSP length: 100 effective length of query: 161 effective length of database: 14,460,918 effective search space: 2328207798 effective search space used: 2328207798 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.