BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24308527 stereocilin [Homo sapiens] (1775 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24308527 stereocilin [Homo sapiens] 3584 0.0 gi|239735575 otoancorin isoform 3 [Homo sapiens] 110 1e-23 gi|24638452 otoancorin isoform 2 [Homo sapiens] 110 1e-23 gi|77404409 otoancorin isoform 1 [Homo sapiens] 110 1e-23 gi|153792074 proline rich 12 [Homo sapiens] 40 0.015 gi|13899257 transmembrane and ubiquitin-like domain containing 1... 40 0.020 gi|209862889 transmembrane and ubiquitin-like domain containing ... 40 0.020 gi|239740825 PREDICTED: hypothetical protein XP_002344066 [Homo ... 39 0.034 gi|40548415 dishevelled associated activator of morphogenesis 2 ... 39 0.059 gi|224458301 family with sequence similarity 186, member A [Homo... 37 0.13 gi|239754267 PREDICTED: hypothetical protein [Homo sapiens] 37 0.17 gi|239742842 PREDICTED: hypothetical protein XP_002342660 [Homo ... 37 0.17 gi|239740775 PREDICTED: hypothetical protein [Homo sapiens] 37 0.17 gi|239740672 PREDICTED: hypothetical protein [Homo sapiens] 37 0.17 gi|239513938 PREDICTED: hypothetical protein [Homo sapiens] 37 0.17 gi|32490559 low density lipoprotein receptor-related protein 10 ... 37 0.17 gi|169234951 coiled-coil domain containing 17 [Homo sapiens] 37 0.22 gi|4503657 forkhead box H1 [Homo sapiens] 35 0.50 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 35 0.50 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 35 0.50 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 35 0.50 gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 35 0.50 gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 35 0.50 gi|110611914 progesterone receptor [Homo sapiens] 34 1.1 gi|239758021 PREDICTED: hypothetical protein [Homo sapiens] 34 1.1 gi|239741335 PREDICTED: hypothetical protein XP_002342177 [Homo ... 34 1.1 gi|5032055 reticulon 2 isoform A [Homo sapiens] 34 1.1 gi|46255005 reticulon 2 isoform B [Homo sapiens] 34 1.1 gi|156105693 PPAR-alpha interacting complex protein 285 isoform ... 34 1.4 gi|156105695 PPAR-alpha interacting complex protein 285 isoform ... 34 1.4 >gi|24308527 stereocilin [Homo sapiens] Length = 1775 Score = 3584 bits (9294), Expect = 0.0 Identities = 1775/1775 (100%), Positives = 1775/1775 (100%) Query: 1 MALSLWPLLLLLLLLLLLSFAVTLAPTGPHSLDPGLSFLKSLLSTLDQAPQGSLSRSRFF 60 MALSLWPLLLLLLLLLLLSFAVTLAPTGPHSLDPGLSFLKSLLSTLDQAPQGSLSRSRFF Sbjct: 1 MALSLWPLLLLLLLLLLLSFAVTLAPTGPHSLDPGLSFLKSLLSTLDQAPQGSLSRSRFF 60 Query: 61 TFLANISSSFEPGRMGEGPVGEPPPLQPPALRLHDFLVTLRGSPDWEPMLGLLGDMLALL 120 TFLANISSSFEPGRMGEGPVGEPPPLQPPALRLHDFLVTLRGSPDWEPMLGLLGDMLALL Sbjct: 61 TFLANISSSFEPGRMGEGPVGEPPPLQPPALRLHDFLVTLRGSPDWEPMLGLLGDMLALL 120 Query: 121 GQEQTPRDFLVHQAGVLGGLVEVLLGALVPGGPPTPTRPPCTRDGPSDCVLAADWLPSLL 180 GQEQTPRDFLVHQAGVLGGLVEVLLGALVPGGPPTPTRPPCTRDGPSDCVLAADWLPSLL Sbjct: 121 GQEQTPRDFLVHQAGVLGGLVEVLLGALVPGGPPTPTRPPCTRDGPSDCVLAADWLPSLL 180 Query: 181 LLLEGTRWQALVQVQPSVDPTNATGLDGREAAPHFLQGLLGLLTPTGELGSKEALWGGLL 240 LLLEGTRWQALVQVQPSVDPTNATGLDGREAAPHFLQGLLGLLTPTGELGSKEALWGGLL Sbjct: 181 LLLEGTRWQALVQVQPSVDPTNATGLDGREAAPHFLQGLLGLLTPTGELGSKEALWGGLL 240 Query: 241 RTVGAPLYAAFQEGLLRVTHSLQDEVFSILGQPEPDTNGQCQGGNLQQLLLWGVRHNLSW 300 RTVGAPLYAAFQEGLLRVTHSLQDEVFSILGQPEPDTNGQCQGGNLQQLLLWGVRHNLSW Sbjct: 241 RTVGAPLYAAFQEGLLRVTHSLQDEVFSILGQPEPDTNGQCQGGNLQQLLLWGVRHNLSW 300 Query: 301 DVQALGFLSGSPPPPPALLHCLSTGVPLPRASQPSAHISPRQRRAITVEALCENHLGPAP 360 DVQALGFLSGSPPPPPALLHCLSTGVPLPRASQPSAHISPRQRRAITVEALCENHLGPAP Sbjct: 301 DVQALGFLSGSPPPPPALLHCLSTGVPLPRASQPSAHISPRQRRAITVEALCENHLGPAP 360 Query: 361 PYSISNFSIHLLCQHTKPATPQPHPSTTAICQTAVWYAVSWAPGAQGWLQACHDQFPDEF 420 PYSISNFSIHLLCQHTKPATPQPHPSTTAICQTAVWYAVSWAPGAQGWLQACHDQFPDEF Sbjct: 361 PYSISNFSIHLLCQHTKPATPQPHPSTTAICQTAVWYAVSWAPGAQGWLQACHDQFPDEF 420 Query: 421 LDAICSNLSFSALSGSNRRLVKRLCAGLLPPPTSCPEGLPPVPLTPDIFWGCFLENETLW 480 LDAICSNLSFSALSGSNRRLVKRLCAGLLPPPTSCPEGLPPVPLTPDIFWGCFLENETLW Sbjct: 421 LDAICSNLSFSALSGSNRRLVKRLCAGLLPPPTSCPEGLPPVPLTPDIFWGCFLENETLW 480 Query: 481 AERLCGEASLQAVPPSNQAWVQHVCQGPTPDVTASPPCHIGPCGERCPDGGSFLVMVCAN 540 AERLCGEASLQAVPPSNQAWVQHVCQGPTPDVTASPPCHIGPCGERCPDGGSFLVMVCAN Sbjct: 481 AERLCGEASLQAVPPSNQAWVQHVCQGPTPDVTASPPCHIGPCGERCPDGGSFLVMVCAN 540 Query: 541 DTMYEVLVPFWPWLAGQCRISRGGNDTCFLEGLLGPLLPSLPPLGPSPLCLTPGPFLLGM 600 DTMYEVLVPFWPWLAGQCRISRGGNDTCFLEGLLGPLLPSLPPLGPSPLCLTPGPFLLGM Sbjct: 541 DTMYEVLVPFWPWLAGQCRISRGGNDTCFLEGLLGPLLPSLPPLGPSPLCLTPGPFLLGM 600 Query: 601 LSQLPRCQSSVPALAHPTRLHYLLRLLTFLLGPGAGGAEAQGMLGRALLLSSLPDNCSFW 660 LSQLPRCQSSVPALAHPTRLHYLLRLLTFLLGPGAGGAEAQGMLGRALLLSSLPDNCSFW Sbjct: 601 LSQLPRCQSSVPALAHPTRLHYLLRLLTFLLGPGAGGAEAQGMLGRALLLSSLPDNCSFW 660 Query: 661 DAFRPEGRRSVLRTIGEYLEQDEEQPTPSGFEPTVNPSSGISKMELLACFSPVLWDLLQR 720 DAFRPEGRRSVLRTIGEYLEQDEEQPTPSGFEPTVNPSSGISKMELLACFSPVLWDLLQR Sbjct: 661 DAFRPEGRRSVLRTIGEYLEQDEEQPTPSGFEPTVNPSSGISKMELLACFSPVLWDLLQR 720 Query: 721 EKSVWALQILVQAYLHMPPENLQQLVLSAEREAAQGFLTLMLQGKLQGKLQVPPSEEQAL 780 EKSVWALQILVQAYLHMPPENLQQLVLSAEREAAQGFLTLMLQGKLQGKLQVPPSEEQAL Sbjct: 721 EKSVWALQILVQAYLHMPPENLQQLVLSAEREAAQGFLTLMLQGKLQGKLQVPPSEEQAL 780 Query: 781 GRLTALLLQRYPRLTSQLFIDLSPLIPFLAVSDLMRFPPSLLANDSVLAAIRDYSPGMRP 840 GRLTALLLQRYPRLTSQLFIDLSPLIPFLAVSDLMRFPPSLLANDSVLAAIRDYSPGMRP Sbjct: 781 GRLTALLLQRYPRLTSQLFIDLSPLIPFLAVSDLMRFPPSLLANDSVLAAIRDYSPGMRP 840 Query: 841 EQKEALAKRLLAPELFGEVPAWPQELLWAVLPLLPHLPLENFLQLSPHQIQALEDSWPAA 900 EQKEALAKRLLAPELFGEVPAWPQELLWAVLPLLPHLPLENFLQLSPHQIQALEDSWPAA Sbjct: 841 EQKEALAKRLLAPELFGEVPAWPQELLWAVLPLLPHLPLENFLQLSPHQIQALEDSWPAA 900 Query: 901 GLGPGHARHVLRSLVNQSVQDGEEQVRRLGPLACFLSPEELQSLVPLSDPTGPVERGLLE 960 GLGPGHARHVLRSLVNQSVQDGEEQVRRLGPLACFLSPEELQSLVPLSDPTGPVERGLLE Sbjct: 901 GLGPGHARHVLRSLVNQSVQDGEEQVRRLGPLACFLSPEELQSLVPLSDPTGPVERGLLE 960 Query: 961 CAANGTLSPEGRVAYELLGVLRSSGGAVLSPRELRVWAPLFSQLGLRFLQELSEPQLRAM 1020 CAANGTLSPEGRVAYELLGVLRSSGGAVLSPRELRVWAPLFSQLGLRFLQELSEPQLRAM Sbjct: 961 CAANGTLSPEGRVAYELLGVLRSSGGAVLSPRELRVWAPLFSQLGLRFLQELSEPQLRAM 1020 Query: 1021 LPVLQGTSVTPAQAVLLLGRLLPRHDLSLEELCSLHLLLPGLSPQTLQAIPRRVLVGACS 1080 LPVLQGTSVTPAQAVLLLGRLLPRHDLSLEELCSLHLLLPGLSPQTLQAIPRRVLVGACS Sbjct: 1021 LPVLQGTSVTPAQAVLLLGRLLPRHDLSLEELCSLHLLLPGLSPQTLQAIPRRVLVGACS 1080 Query: 1081 CLAPELSRLSACQTAALLQTFRVKDGVKNMGTTGAGPAVCIPGQPIPTTWPDCLLPLLPL 1140 CLAPELSRLSACQTAALLQTFRVKDGVKNMGTTGAGPAVCIPGQPIPTTWPDCLLPLLPL Sbjct: 1081 CLAPELSRLSACQTAALLQTFRVKDGVKNMGTTGAGPAVCIPGQPIPTTWPDCLLPLLPL 1140 Query: 1141 KLLQLDSLALLANRRRYWELPWSEQQAQFLWKKMQVPTNLTLRNLQALGTLAGGMSCEFL 1200 KLLQLDSLALLANRRRYWELPWSEQQAQFLWKKMQVPTNLTLRNLQALGTLAGGMSCEFL Sbjct: 1141 KLLQLDSLALLANRRRYWELPWSEQQAQFLWKKMQVPTNLTLRNLQALGTLAGGMSCEFL 1200 Query: 1201 QQINSMVDFLEVVHMIYQLPTRVRGSLRACIWAELQRRMAMPEPEWTTVGPELNGLDSKL 1260 QQINSMVDFLEVVHMIYQLPTRVRGSLRACIWAELQRRMAMPEPEWTTVGPELNGLDSKL Sbjct: 1201 QQINSMVDFLEVVHMIYQLPTRVRGSLRACIWAELQRRMAMPEPEWTTVGPELNGLDSKL 1260 Query: 1261 LLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKETPVSGE 1320 LLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKETPVSGE Sbjct: 1261 LLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKETPVSGE 1320 Query: 1321 VLETLGPLVGFLGTESTRQIPLQILLSHLSQLQGFCLGETFATELGWLLLQESVLGKPEL 1380 VLETLGPLVGFLGTESTRQIPLQILLSHLSQLQGFCLGETFATELGWLLLQESVLGKPEL Sbjct: 1321 VLETLGPLVGFLGTESTRQIPLQILLSHLSQLQGFCLGETFATELGWLLLQESVLGKPEL 1380 Query: 1381 WSQDEVEQAGRLVFTLSTEAISLIPREALGPETLERLLEKQQSWEQSRVGQLCREPQLAA 1440 WSQDEVEQAGRLVFTLSTEAISLIPREALGPETLERLLEKQQSWEQSRVGQLCREPQLAA Sbjct: 1381 WSQDEVEQAGRLVFTLSTEAISLIPREALGPETLERLLEKQQSWEQSRVGQLCREPQLAA 1440 Query: 1441 KKAALVAGVVRPAAEDLPEPVPNCADVRGTFPAAWSATQIAEMELSDFEDCLTLFAGDPG 1500 KKAALVAGVVRPAAEDLPEPVPNCADVRGTFPAAWSATQIAEMELSDFEDCLTLFAGDPG Sbjct: 1441 KKAALVAGVVRPAAEDLPEPVPNCADVRGTFPAAWSATQIAEMELSDFEDCLTLFAGDPG 1500 Query: 1501 LGPEELRAAMGKAKQLWGPPRGFRPEQILQLGRLLIGLGDRELQELILVDWGVLSTLGQI 1560 LGPEELRAAMGKAKQLWGPPRGFRPEQILQLGRLLIGLGDRELQELILVDWGVLSTLGQI Sbjct: 1501 LGPEELRAAMGKAKQLWGPPRGFRPEQILQLGRLLIGLGDRELQELILVDWGVLSTLGQI 1560 Query: 1561 DGWSTTQLRIVVSSFLRQSGRHVSHLDFVHLTALGYTLCGLRPEELQHISSWEFSQAALF 1620 DGWSTTQLRIVVSSFLRQSGRHVSHLDFVHLTALGYTLCGLRPEELQHISSWEFSQAALF Sbjct: 1561 DGWSTTQLRIVVSSFLRQSGRHVSHLDFVHLTALGYTLCGLRPEELQHISSWEFSQAALF 1620 Query: 1621 LGTLHLQCSEEQLEVLAHLLVLPGGFGPISNWGPEIFTEIGTIAAGIPDLALSALLRGQI 1680 LGTLHLQCSEEQLEVLAHLLVLPGGFGPISNWGPEIFTEIGTIAAGIPDLALSALLRGQI Sbjct: 1621 LGTLHLQCSEEQLEVLAHLLVLPGGFGPISNWGPEIFTEIGTIAAGIPDLALSALLRGQI 1680 Query: 1681 QGVTPLAISVIPPPKFAVVFSPIQLSSLTSAQAVAVTPEQMAFLSPEQRRAVAWAQHEGK 1740 QGVTPLAISVIPPPKFAVVFSPIQLSSLTSAQAVAVTPEQMAFLSPEQRRAVAWAQHEGK Sbjct: 1681 QGVTPLAISVIPPPKFAVVFSPIQLSSLTSAQAVAVTPEQMAFLSPEQRRAVAWAQHEGK 1740 Query: 1741 ESPEQQGRSTAWGLQDWSRPSWSLVLTISFLGHLL 1775 ESPEQQGRSTAWGLQDWSRPSWSLVLTISFLGHLL Sbjct: 1741 ESPEQQGRSTAWGLQDWSRPSWSLVLTISFLGHLL 1775 >gi|239735575 otoancorin isoform 3 [Homo sapiens] Length = 1060 Score = 110 bits (275), Expect = 1e-23 Identities = 94/332 (28%), Positives = 140/332 (42%), Gaps = 29/332 (8%) Query: 1450 VRPAAEDLP--EPVPNCADVRGTFP----------AAWSATQIAEMELSDFEDCLTLFAG 1497 VR +++ +P +P+P C V A W+ + ME F + L Sbjct: 717 VRNSSDKIPSYDPMPGCHGVVAPSSDDIFKLAEANACWALEDLRCMEEDTFIRTVELLGA 776 Query: 1498 DPGLGPEELRAAMGKAKQLWGPPRGFRPEQILQLGRLLIGLGDRELQELILVDWGVLSTL 1557 G +L KA Q+W P +R I+ LGR+ + L + EL++L L +++L Sbjct: 777 VQGFSRPQLMTLKEKAIQVWDMPSYWREHHIVSLGRIALALNESELEQLDLSSIDTVASL 836 Query: 1558 GQIDGWSTTQLRIVVSSFLRQSGRHVSHLDFVHLTALGYTLCGLRPEELQHISSWEFSQA 1617 W+ Q ++ +L SG + L HL LG TLC + E+ I EF Sbjct: 837 SWQTEWTPGQAESILQGYLDDSGYSIQDLKSFHLVGLGATLCAINITEIPLIKISEFRVV 896 Query: 1618 ALFLGTLHLQCSEEQLEVLAHLLVLPGGFGPISNWGPEIFTEIGTIAAGIPDLALSALLR 1677 +GT L CS L + FG + W + E+GTIAAG+ L L + Sbjct: 897 VARIGT--LLCSTHVLAEFKRKAEVV--FGDPTEWTSSVLQELGTIAAGLTKAELRMLDK 952 Query: 1678 GQIQGVTPLAISVIPPPKFAVVFSPIQLSSLTSAQAVAVTPEQMAFLSPEQRRAVAWA-- 1735 + P AI +P F + S Q++SL A AVT Q LSP Q +++ A Sbjct: 953 DLMPYFQPSAIKCLPDEIFKEL-SAEQIASLGPENAAAVTHAQRRRLSPLQLQSLQQALD 1011 Query: 1736 ---QHEGKESPEQQG-------RSTAWGLQDW 1757 H +++P G RS A LQ W Sbjct: 1012 GAKTHSWQDAPASAGPTRTSSSRSPAGALQSW 1043 Score = 35.0 bits (79), Expect = 0.65 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 5/92 (5%) Query: 1526 EQILQLGRLLIGLGDRELQELIL-VDWGVLSTLGQIDGWSTTQLRIVVSSFLRQSGRHVS 1584 E + L ++GL +L+ L G +STL Q+ GW+ +Q+ I+ + +L H Sbjct: 306 ETLGSLSDAVVGLTYSQLESLSPEAVHGAISTLNQVSGWAKSQVIILSAKYL----AHEK 361 Query: 1585 HLDFVHLTALGYTLCGLRPEELQHISSWEFSQ 1616 L F +++ +G L G+ + + + SQ Sbjct: 362 VLSFYNVSQMGALLAGVSTQAFCSMKRKDISQ 393 >gi|24638452 otoancorin isoform 2 [Homo sapiens] Length = 815 Score = 110 bits (275), Expect = 1e-23 Identities = 94/332 (28%), Positives = 140/332 (42%), Gaps = 29/332 (8%) Query: 1450 VRPAAEDLP--EPVPNCADVRGTFP----------AAWSATQIAEMELSDFEDCLTLFAG 1497 VR +++ +P +P+P C V A W+ + ME F + L Sbjct: 472 VRNSSDKIPSYDPMPGCHGVVAPSSDDIFKLAEANACWALEDLRCMEEDTFIRTVELLGA 531 Query: 1498 DPGLGPEELRAAMGKAKQLWGPPRGFRPEQILQLGRLLIGLGDRELQELILVDWGVLSTL 1557 G +L KA Q+W P +R I+ LGR+ + L + EL++L L +++L Sbjct: 532 VQGFSRPQLMTLKEKAIQVWDMPSYWREHHIVSLGRIALALNESELEQLDLSSIDTVASL 591 Query: 1558 GQIDGWSTTQLRIVVSSFLRQSGRHVSHLDFVHLTALGYTLCGLRPEELQHISSWEFSQA 1617 W+ Q ++ +L SG + L HL LG TLC + E+ I EF Sbjct: 592 SWQTEWTPGQAESILQGYLDDSGYSIQDLKSFHLVGLGATLCAINITEIPLIKISEFRVV 651 Query: 1618 ALFLGTLHLQCSEEQLEVLAHLLVLPGGFGPISNWGPEIFTEIGTIAAGIPDLALSALLR 1677 +GT L CS L + FG + W + E+GTIAAG+ L L + Sbjct: 652 VARIGT--LLCSTHVLAEFKRKAEVV--FGDPTEWTSSVLQELGTIAAGLTKAELRMLDK 707 Query: 1678 GQIQGVTPLAISVIPPPKFAVVFSPIQLSSLTSAQAVAVTPEQMAFLSPEQRRAVAWA-- 1735 + P AI +P F + S Q++SL A AVT Q LSP Q +++ A Sbjct: 708 DLMPYFQPSAIKCLPDEIFKEL-SAEQIASLGPENAAAVTHAQRRRLSPLQLQSLQQALD 766 Query: 1736 ---QHEGKESPEQQG-------RSTAWGLQDW 1757 H +++P G RS A LQ W Sbjct: 767 GAKTHSWQDAPASAGPTRTSSSRSPAGALQSW 798 Score = 35.0 bits (79), Expect = 0.65 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 5/92 (5%) Query: 1526 EQILQLGRLLIGLGDRELQELIL-VDWGVLSTLGQIDGWSTTQLRIVVSSFLRQSGRHVS 1584 E + L ++GL +L+ L G +STL Q+ GW+ +Q+ I+ + +L H Sbjct: 61 ETLGSLSDAVVGLTYSQLESLSPEAVHGAISTLNQVSGWAKSQVIILSAKYL----AHEK 116 Query: 1585 HLDFVHLTALGYTLCGLRPEELQHISSWEFSQ 1616 L F +++ +G L G+ + + + SQ Sbjct: 117 VLSFYNVSQMGALLAGVSTQAFCSMKRKDISQ 148 >gi|77404409 otoancorin isoform 1 [Homo sapiens] Length = 1139 Score = 110 bits (275), Expect = 1e-23 Identities = 94/332 (28%), Positives = 140/332 (42%), Gaps = 29/332 (8%) Query: 1450 VRPAAEDLP--EPVPNCADVRGTFP----------AAWSATQIAEMELSDFEDCLTLFAG 1497 VR +++ +P +P+P C V A W+ + ME F + L Sbjct: 796 VRNSSDKIPSYDPMPGCHGVVAPSSDDIFKLAEANACWALEDLRCMEEDTFIRTVELLGA 855 Query: 1498 DPGLGPEELRAAMGKAKQLWGPPRGFRPEQILQLGRLLIGLGDRELQELILVDWGVLSTL 1557 G +L KA Q+W P +R I+ LGR+ + L + EL++L L +++L Sbjct: 856 VQGFSRPQLMTLKEKAIQVWDMPSYWREHHIVSLGRIALALNESELEQLDLSSIDTVASL 915 Query: 1558 GQIDGWSTTQLRIVVSSFLRQSGRHVSHLDFVHLTALGYTLCGLRPEELQHISSWEFSQA 1617 W+ Q ++ +L SG + L HL LG TLC + E+ I EF Sbjct: 916 SWQTEWTPGQAESILQGYLDDSGYSIQDLKSFHLVGLGATLCAINITEIPLIKISEFRVV 975 Query: 1618 ALFLGTLHLQCSEEQLEVLAHLLVLPGGFGPISNWGPEIFTEIGTIAAGIPDLALSALLR 1677 +GT L CS L + FG + W + E+GTIAAG+ L L + Sbjct: 976 VARIGT--LLCSTHVLAEFKRKAEVV--FGDPTEWTSSVLQELGTIAAGLTKAELRMLDK 1031 Query: 1678 GQIQGVTPLAISVIPPPKFAVVFSPIQLSSLTSAQAVAVTPEQMAFLSPEQRRAVAWA-- 1735 + P AI +P F + S Q++SL A AVT Q LSP Q +++ A Sbjct: 1032 DLMPYFQPSAIKCLPDEIFKEL-SAEQIASLGPENAAAVTHAQRRRLSPLQLQSLQQALD 1090 Query: 1736 ---QHEGKESPEQQG-------RSTAWGLQDW 1757 H +++P G RS A LQ W Sbjct: 1091 GAKTHSWQDAPASAGPTRTSSSRSPAGALQSW 1122 Score = 35.0 bits (79), Expect = 0.65 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 5/92 (5%) Query: 1526 EQILQLGRLLIGLGDRELQELIL-VDWGVLSTLGQIDGWSTTQLRIVVSSFLRQSGRHVS 1584 E + L ++GL +L+ L G +STL Q+ GW+ +Q+ I+ + +L H Sbjct: 385 ETLGSLSDAVVGLTYSQLESLSPEAVHGAISTLNQVSGWAKSQVIILSAKYL----AHEK 440 Query: 1585 HLDFVHLTALGYTLCGLRPEELQHISSWEFSQ 1616 L F +++ +G L G+ + + + SQ Sbjct: 441 VLSFYNVSQMGALLAGVSTQAFCSMKRKDISQ 472 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 40.4 bits (93), Expect = 0.015 Identities = 53/221 (23%), Positives = 79/221 (35%), Gaps = 51/221 (23%) Query: 189 QALVQVQPSVDPTNATGLDGREAAPHFLQGLLGLLTPTGELGSKEALWGGLLRTVGAPLY 248 Q L+Q + A GL G + A +GL G GG G P Sbjct: 644 QHLLQAPSPPRTSGADGLVGEDGAADASKGLGGS--------------GGAGGPPGTPYE 689 Query: 249 AAFQE-------GLLRVTHSLQDEVFSIL----GQPEPDTNGQCQGGNLQQLLLWGVRHN 297 A ++ ++R + SL + + L G+ + G +GG + L V H Sbjct: 690 LAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHY 749 Query: 298 LSWDVQALGFLSGSPPPPPALLHCLSTGVPLPRASQPSAH-------------ISPRQRR 344 + + FL SPPPPP P +++QP+ H + P Sbjct: 750 GAGAKELGAFLQKSPPPPP----------PTAQSTQPTPHGLLLEAGGPDLPLVLPPPPP 799 Query: 345 AITVEALCENHLGPAPPYSISNFSIHLLCQHTKPATPQPHP 385 + L P+P S S +HLL T+ PQP P Sbjct: 800 QLLPSVLSH---APSPSPSASKVGVHLLEPATRDGAPQPPP 837 >gi|13899257 transmembrane and ubiquitin-like domain containing 1 isoform 1 [Homo sapiens] Length = 246 Score = 40.0 bits (92), Expect = 0.020 Identities = 33/100 (33%), Positives = 44/100 (44%), Gaps = 15/100 (15%) Query: 121 GQEQTPRDFLVHQAGVLGGLVEVLLGALVPG------------GPPTPTRPPCTRDGPSD 168 G+EQ R L++Q +LG + L +P GPP P PP + GPS Sbjct: 135 GREQQVR--LIYQGQLLGDDTQTLGSLHLPPNCVLHCHVSTRVGPPNPPCPPGSEPGPSG 192 Query: 169 CVLAADWLPSLLLLLEGTRWQALVQVQPSVDPTNATGLDG 208 + + LP LLLLL W +Q +P T GL G Sbjct: 193 LEIGSLLLPLLLLLLL-LLWYCQIQYRPFFPLTATLGLAG 231 >gi|209862889 transmembrane and ubiquitin-like domain containing 1 isoform 2 [Homo sapiens] Length = 246 Score = 40.0 bits (92), Expect = 0.020 Identities = 33/100 (33%), Positives = 44/100 (44%), Gaps = 15/100 (15%) Query: 121 GQEQTPRDFLVHQAGVLGGLVEVLLGALVPG------------GPPTPTRPPCTRDGPSD 168 G+EQ R L++Q +LG + L +P GPP P PP + GPS Sbjct: 135 GREQQVR--LIYQGQLLGDDTQTLGSLHLPPNCVLHCHVSTRVGPPNPPCPPGSEPGPSG 192 Query: 169 CVLAADWLPSLLLLLEGTRWQALVQVQPSVDPTNATGLDG 208 + + LP LLLLL W +Q +P T GL G Sbjct: 193 LEIGSLLLPLLLLLLL-LLWYCQIQYRPFFPLTATLGLAG 231 >gi|239740825 PREDICTED: hypothetical protein XP_002344066 [Homo sapiens] Length = 514 Score = 39.3 bits (90), Expect = 0.034 Identities = 44/161 (27%), Positives = 74/161 (45%), Gaps = 11/161 (6%) Query: 1256 LDSKLLLDL-PIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKE 1314 LDS+L+ L P++++ L +E + ++ L +L+A+ L L + LAP E Sbjct: 343 LDSELVAVLAPLEVV--LESELVAVLAPLESVLDSELVAVLALLDTVLDSELVAVLAPLE 400 Query: 1315 TPVSGEVLETLGPLVGFLGTESTRQI-PLQILLSHLSQLQGFCLGETFATELGWLLLQES 1373 + E++ L PL G L +E + PL+++L L +EL +L+ Sbjct: 401 VTLDPELVTVLAPLEGVLDSELVAVLAPLEVVLDSELVAMLIPLDAVLNSELVAVLIPLE 460 Query: 1374 VLGKPELWSQDEVEQAGRLVFTLSTEAIS-LIPRE-ALGPE 1412 V +W+ + V L TL E ++ L P E L PE Sbjct: 461 V-----VWNSELVTMLTPLEVTLDPEMVAVLTPLEVTLDPE 496 Score = 33.9 bits (76), Expect = 1.4 Identities = 46/147 (31%), Positives = 63/147 (42%), Gaps = 38/147 (25%) Query: 1238 RMAMPEPEWTTVGPELNG--------LDSKLL-----LD--LPIQLMDRLSNESIMLVVE 1282 R A+PEP T+ PEL LDS+L+ LD L +L+ L++ ++L E Sbjct: 32 RAAVPEPAEVTLDPELVAVLAPLEVVLDSELVTVLIPLDTVLDSELVAVLASLEVVLESE 91 Query: 1283 LVQ-RAP-------EQLLALTPLH--------------QAALAERALQNLAPKETPVSGE 1320 LV AP E + LTPL L + LAP E + E Sbjct: 92 LVAVLAPLEVVLDSELVAVLTPLEVVLDSELVAVLAPLDTVLDSELVAVLAPLEVVLDSE 151 Query: 1321 VLETLGPLVGFLGTE-STRQIPLQILL 1346 ++ L PL G L +E T IPL +L Sbjct: 152 LVAVLAPLEGVLDSELVTVLIPLDTVL 178 >gi|40548415 dishevelled associated activator of morphogenesis 2 [Homo sapiens] Length = 1067 Score = 38.5 bits (88), Expect = 0.059 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 12/71 (16%) Query: 310 GSPPPPPALLHCLSTGVPLPRASQPSAHISPRQRRAITVEALCENHLGPAPPYSISNFSI 369 G PP PP CL G+PLP+ PS+ + R++R P P + + +F+ Sbjct: 563 GGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRV------------PQPSHPLKSFNW 610 Query: 370 HLLCQHTKPAT 380 L + P T Sbjct: 611 VKLNEERVPGT 621 >gi|224458301 family with sequence similarity 186, member A [Homo sapiens] Length = 2351 Score = 37.4 bits (85), Expect = 0.13 Identities = 108/464 (23%), Positives = 174/464 (37%), Gaps = 89/464 (19%) Query: 735 LHMPPENLQQ--LVLSAEREAAQGFLTLMLQGKLQGKLQVPPSEEQALGRLTALLLQRYP 792 +H+ P+ Q+ + L+ ++ AQG +TL LQ + + + P + QAL L P Sbjct: 1073 IHLTPQQAQEVGITLTPQQAQAQG-ITLTLQQAQELGIPLTPQQAQALEILFT------P 1125 Query: 793 RLTSQLFIDLSPLIPFLAVSDLMRFPPSLLANDSVLAAIRDYSPGMRPEQKEALAKRLLA 852 + L I L+P L +D +PG+ ++A Sbjct: 1126 QQAQALGIPLTP--------------QQTQVQGITLTPQQDQAPGISLTTQQA------- 1164 Query: 853 PELFGEVPAWPQELLWAVLPLLPHLPLENFLQLSPHQIQALEDSWPAAGLGPGHARHVLR 912 + G +P PQ+ +PL P E + L+P Q QAL S L P A+ + Sbjct: 1165 -QKLG-IPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVS-----LTPQQAQELGI 1217 Query: 913 SLVNQSVQD-----GEEQVRRLGPLACFLSPEELQSLVPLSDPTGPVERGLLECAANGTL 967 L Q Q +Q ++LG L+P++ Q+L P E G+ L Sbjct: 1218 PLTPQQAQALGITLTLQQAQQLG---IPLTPQQAQALGITLTPKQVQELGI-------PL 1267 Query: 968 SPEGRVAYELLGVLRSSGGAVLSPRELR-VWAPLFSQLGLRFLQELSEPQLRAMLPVLQG 1026 +P+ A G L+P++ + + PL Q L+ Q +A+ G Sbjct: 1268 TPQQAQAL----------GITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQAL-----G 1312 Query: 1027 TSVTPAQAVLLLGRLLPRHDLSLEELCSLHLLLPGLSPQTLQAIPRRVLVGACSCLAPEL 1086 TP QA L L P+ + E L+PQ QA+ + L L Sbjct: 1313 IPFTPQQAQALGIPLTPQQAQTQEIT---------LTPQQAQALGMPLTTQQAQELGIPL 1363 Query: 1087 SRLSACQTAALLQTFRVKDGVKNMGTTGAGPAVCIPGQPIPTTWPDCL-LPLLPLKLLQL 1145 + A L T + ++ +G G P+ T L +PL P + +L Sbjct: 1364 TPQHAQALGMPLTTQQAQE----LGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQEL 1419 Query: 1146 DSLALLANRRRYWELPWSEQQAQFLWKKMQVPTNLTLRNLQALG 1189 + + + E+ + QQAQ L LT + Q LG Sbjct: 1420 -GIPFTPQQAQAQEITLTPQQAQALGMP------LTAQQAQELG 1456 Score = 33.9 bits (76), Expect = 1.4 Identities = 53/191 (27%), Positives = 83/191 (43%), Gaps = 29/191 (15%) Query: 769 KLQVPPSEEQALGR-LTALLLQRYP-RLTSQLFIDLS-PLIPFLAVS-DLMRFPPSLLAN 824 ++ + P + QALG LTA Q LT Q +L PL P A + + PP Sbjct: 1432 EITLTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQA--- 1488 Query: 825 DSVLAAIRDYSPGMRPEQKEALAKRLLAPELFG-EVPAWPQELLWAVLPLLPHLPLENFL 883 ++ + P+Q +AL L+ P+ +P PQ+ +PL+P E + Sbjct: 1489 -------QELGIPLTPQQAQALGILLIPPQAQELGIPLTPQQAQALGIPLIPPQAQELGI 1541 Query: 884 QLSPHQIQALEDSWPAAGLGPGHARHVLRSLVNQSVQD-----GEEQVRRLGPLACFLSP 938 L+P Q+QAL L P A+ + L Q Q +Q + LG L+P Sbjct: 1542 PLTPQQVQAL-----GIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELG---IPLTP 1593 Query: 939 EELQSL-VPLS 948 ++ Q L +PL+ Sbjct: 1594 QQAQELGIPLT 1604 Score = 32.0 bits (71), Expect = 5.5 Identities = 52/213 (24%), Positives = 86/213 (40%), Gaps = 30/213 (14%) Query: 739 PENLQQLVLSAEREAAQGFLTLMLQGKLQGKLQVP--PSEEQALGRLTALLLQRYPRLTS 796 P Q+L + + AQ L++ + Q +L +P P + QALG + P Sbjct: 1485 PPQAQELGIPLTPQQAQALGILLIPPQAQ-ELGIPLTPQQAQALG------IPLIPPQAQ 1537 Query: 797 QLFIDLSP---------LIPFLAVS-DLMRFPPSLLANDSVLAAIRDYSPG--MRPEQKE 844 +L I L+P LIP A ++ P A L + G + P+Q + Sbjct: 1538 ELGIPLTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQ 1597 Query: 845 ALAKRLLAPELFGE-VPAWPQELLWAVLPLLPHLPLENFLQLSPHQIQAL------EDSW 897 L L + + +P PQ+ + L P + L+P Q QAL ++W Sbjct: 1598 ELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNAW 1657 Query: 898 PAAGLGPGHARHVLRSLVNQSVQDGEEQVRRLG 930 +A H L S +N ++ +EQ+ +LG Sbjct: 1658 VSAVTLTSEQTHALESPMN--LEQAQEQLLKLG 1688 >gi|239754267 PREDICTED: hypothetical protein [Homo sapiens] Length = 454 Score = 37.0 bits (84), Expect = 0.17 Identities = 43/160 (26%), Positives = 71/160 (44%), Gaps = 9/160 (5%) Query: 1256 LDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKET 1315 LDS+L+ L + L L +E + ++ L +L+A+ + L + LAP E Sbjct: 283 LDSELVAVLAL-LDTVLDSELVAVLAPLEVVLDSELVAVLASLEVVLESELVAVLAPLEV 341 Query: 1316 PVSGEVLETLGPLVGFLGTESTRQI-PLQILLSHLSQLQGFCLGETFATELGWLLLQESV 1374 + E++ L PL G L +E + PL+++L L +EL +L+ V Sbjct: 342 VLESELVAVLAPLEGVLDSELVAVLAPLEVVLDSELVAMLIPLDAVLNSELVAVLIPLEV 401 Query: 1375 LGKPELWSQDEVEQAGRLVFTLSTEAIS-LIPRE-ALGPE 1412 +W+ + V L TL E ++ L P E L PE Sbjct: 402 -----VWNSELVTMLTPLEVTLDPEMVAVLTPLEVTLDPE 436 Score = 36.2 bits (82), Expect = 0.29 Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 9/110 (8%) Query: 1238 RMAMPEPEWTTVGPELNGLDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPL 1297 R A+PEP T+ PEL + + L + L +L+ L+ +L ELV L PL Sbjct: 32 RAAVPEPAEVTLDPELVAVLAPLEVVLDSELVAVLAPLDTVLDSELV-------AVLAPL 84 Query: 1298 HQAALAERALQNLAPKETPVSGEVLETLGPLVGFLGTESTRQI-PLQILL 1346 + L + LAP +T + E++ L PL L E + PL+++L Sbjct: 85 -EVVLDSEVVAVLAPLDTVLDSELVAVLVPLEVVLDPELVAVLAPLEVVL 133 Score = 31.6 bits (70), Expect = 7.2 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 9/109 (8%) Query: 1239 MAMPEPEWTTVGPELNGLDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLH 1298 +A+ P + PEL + + L + L +L+ L+ ++L ELV L PL Sbjct: 108 VAVLVPLEVVLDPELVAVLAPLEVVLDSELVAVLAPLEVVLDSELVA-------VLAPL- 159 Query: 1299 QAALAERALQNLAPKETPVSGEVLETLGPLVGFLGTE-STRQIPLQILL 1346 + L + LAP E + E++ L PL G L +E T IPL +L Sbjct: 160 EVVLESELVAVLAPLEVVLDSELVAVLAPLEGVLDSELVTVLIPLDTVL 208 >gi|239742842 PREDICTED: hypothetical protein XP_002342660 [Homo sapiens] Length = 454 Score = 37.0 bits (84), Expect = 0.17 Identities = 43/160 (26%), Positives = 71/160 (44%), Gaps = 9/160 (5%) Query: 1256 LDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKET 1315 LDS+L+ L + L L +E + ++ L +L+A+ + L + LAP E Sbjct: 283 LDSELVAVLAL-LDTVLDSELVAVLAPLEVVLDSELVAVLASLEVVLESELVAVLAPLEV 341 Query: 1316 PVSGEVLETLGPLVGFLGTESTRQI-PLQILLSHLSQLQGFCLGETFATELGWLLLQESV 1374 + E++ L PL G L +E + PL+++L L +EL +L+ V Sbjct: 342 VLESELVAVLAPLEGVLDSELVAVLAPLEVVLDSELVAMLIPLDTVLNSELVAVLIPLEV 401 Query: 1375 LGKPELWSQDEVEQAGRLVFTLSTEAIS-LIPRE-ALGPE 1412 +W+ + V L TL E ++ L P E L PE Sbjct: 402 -----VWNSELVTMLTPLEVTLDPEMVAVLTPLEVTLDPE 436 Score = 36.2 bits (82), Expect = 0.29 Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 9/110 (8%) Query: 1238 RMAMPEPEWTTVGPELNGLDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPL 1297 R A+PEP T+ PEL + + L + L +L+ L+ +L ELV L PL Sbjct: 32 RAAVPEPAEVTLDPELVAVLAPLEVVLDSELVAVLAPLDTVLDSELV-------AVLAPL 84 Query: 1298 HQAALAERALQNLAPKETPVSGEVLETLGPLVGFLGTESTRQI-PLQILL 1346 + L + LAP +T + E++ L PL L E + PL+++L Sbjct: 85 -EVVLDSEVVAVLAPLDTVLDSELVAVLVPLEVVLDPELVAVLAPLEVVL 133 Score = 31.6 bits (70), Expect = 7.2 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 9/109 (8%) Query: 1239 MAMPEPEWTTVGPELNGLDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLH 1298 +A+ P + PEL + + L + L +L+ L+ ++L ELV L PL Sbjct: 108 VAVLVPLEVVLDPELVAVLAPLEVVLDSELVAVLAPLEVVLDSELVA-------VLAPL- 159 Query: 1299 QAALAERALQNLAPKETPVSGEVLETLGPLVGFLGTE-STRQIPLQILL 1346 + L + LAP E + E++ L PL G L +E T IPL +L Sbjct: 160 EVVLESELVAVLAPLEVVLDSELVAVLAPLEGVLDSELVTVLIPLDTVL 208 >gi|239740775 PREDICTED: hypothetical protein [Homo sapiens] Length = 454 Score = 37.0 bits (84), Expect = 0.17 Identities = 43/160 (26%), Positives = 71/160 (44%), Gaps = 9/160 (5%) Query: 1256 LDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKET 1315 LDS+L+ L + L L +E + ++ L +L+A+ + L + LAP E Sbjct: 283 LDSELVAVLAL-LDTVLDSELVTVLAPLEVVLDSELVAVLASLEVVLESELVAVLAPLEV 341 Query: 1316 PVSGEVLETLGPLVGFLGTESTRQI-PLQILLSHLSQLQGFCLGETFATELGWLLLQESV 1374 + E++ L PL G L +E + PL+++L L +EL +L+ V Sbjct: 342 VLESELVAVLAPLEGVLDSELVAVLAPLEVVLDSELVAMLIPLDTVLNSELVAVLIPLEV 401 Query: 1375 LGKPELWSQDEVEQAGRLVFTLSTEAIS-LIPRE-ALGPE 1412 +W+ + V L TL E ++ L P E L PE Sbjct: 402 -----VWNSELVTMLTPLEVTLDPEMVAVLTPLEVTLDPE 436 Score = 36.2 bits (82), Expect = 0.29 Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 9/110 (8%) Query: 1238 RMAMPEPEWTTVGPELNGLDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPL 1297 R A+PEP T+ PEL + + L + L +L+ L+ +L ELV L PL Sbjct: 32 RAAVPEPAEVTLDPELVAVLAPLEVVLDSELVAVLAPLDTVLDSELV-------AVLAPL 84 Query: 1298 HQAALAERALQNLAPKETPVSGEVLETLGPLVGFLGTESTRQI-PLQILL 1346 + L + LAP +T + E++ L PL L E + PL+++L Sbjct: 85 -EVVLDSEVVAVLAPLDTVLDSELVAVLVPLEVVLDPELVAVLAPLEVVL 133 Score = 31.6 bits (70), Expect = 7.2 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 9/109 (8%) Query: 1239 MAMPEPEWTTVGPELNGLDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLH 1298 +A+ P + PEL + + L + L +L+ L+ ++L ELV L PL Sbjct: 108 VAVLVPLEVVLDPELVAVLAPLEVVLDSELVAVLAPLEVVLDSELVA-------VLAPL- 159 Query: 1299 QAALAERALQNLAPKETPVSGEVLETLGPLVGFLGTE-STRQIPLQILL 1346 + L + LAP E + E++ L PL G L +E T IPL +L Sbjct: 160 EVVLESELVAVLAPLEVVLDSELVAVLAPLEGVLDSELVTVLIPLDTVL 208 >gi|239740672 PREDICTED: hypothetical protein [Homo sapiens] Length = 454 Score = 37.0 bits (84), Expect = 0.17 Identities = 43/160 (26%), Positives = 71/160 (44%), Gaps = 9/160 (5%) Query: 1256 LDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKET 1315 LDS+L+ L + L L +E + ++ L +L+A+ + L + LAP E Sbjct: 283 LDSELVAVLAL-LDTVLDSELVAVLAPLEVVLDSELVAVLASLEVVLESELVAVLAPLEV 341 Query: 1316 PVSGEVLETLGPLVGFLGTESTRQI-PLQILLSHLSQLQGFCLGETFATELGWLLLQESV 1374 + E++ L PL G L +E + PL+++L L +EL +L+ V Sbjct: 342 VLESELVAVLAPLEGVLDSELVAVLAPLEVVLDSELVAMLIPLDAVLNSELVAVLIPLEV 401 Query: 1375 LGKPELWSQDEVEQAGRLVFTLSTEAIS-LIPRE-ALGPE 1412 +W+ + V L TL E ++ L P E L PE Sbjct: 402 -----VWNSELVTMLTPLEVTLDPEMVAVLTPLEVTLDPE 436 Score = 36.2 bits (82), Expect = 0.29 Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 9/110 (8%) Query: 1238 RMAMPEPEWTTVGPELNGLDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPL 1297 R A+PEP T+ PEL + + L + L +L+ L+ +L ELV L PL Sbjct: 32 RAAVPEPAEVTLDPELVAVLAPLEVVLDSELVAVLAPLDTVLDSELV-------AVLAPL 84 Query: 1298 HQAALAERALQNLAPKETPVSGEVLETLGPLVGFLGTESTRQI-PLQILL 1346 + L + LAP +T + E++ L PL L E + PL+++L Sbjct: 85 -EVVLDSEVVAVLAPLDTVLDSELVAVLVPLEVVLDPELVAVLAPLEVVL 133 Score = 31.6 bits (70), Expect = 7.2 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 9/109 (8%) Query: 1239 MAMPEPEWTTVGPELNGLDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLH 1298 +A+ P + PEL + + L + L +L+ L+ ++L ELV L PL Sbjct: 108 VAVLVPLEVVLDPELVAVLAPLEVVLDSELVAVLAPLEVVLDSELVA-------VLAPL- 159 Query: 1299 QAALAERALQNLAPKETPVSGEVLETLGPLVGFLGTE-STRQIPLQILL 1346 + L + LAP E + E++ L PL G L +E T IPL +L Sbjct: 160 EVVLESELVAVLAPLEVVLDSELVAVLAPLEGVLDSELVTVLIPLDTVL 208 >gi|239513938 PREDICTED: hypothetical protein [Homo sapiens] Length = 454 Score = 37.0 bits (84), Expect = 0.17 Identities = 43/160 (26%), Positives = 71/160 (44%), Gaps = 9/160 (5%) Query: 1256 LDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLHQAALAERALQNLAPKET 1315 LDS+L+ L + L L +E + ++ L +L+A+ + L + LAP E Sbjct: 283 LDSELVAVLAL-LDTVLDSELVAVLAPLEVVLDSELVAVLASLEVVLESELVAVLAPLEV 341 Query: 1316 PVSGEVLETLGPLVGFLGTESTRQI-PLQILLSHLSQLQGFCLGETFATELGWLLLQESV 1374 + E++ L PL G L +E + PL+++L L +EL +L+ V Sbjct: 342 VLESELVAVLAPLEGVLDSELVAVLAPLEVVLDSELVAMLIPLDAVLNSELVAVLIPLEV 401 Query: 1375 LGKPELWSQDEVEQAGRLVFTLSTEAIS-LIPRE-ALGPE 1412 +W+ + V L TL E ++ L P E L PE Sbjct: 402 -----VWNSELVTMLTPLEVTLDPEMVAVLTPLEVTLDPE 436 Score = 36.2 bits (82), Expect = 0.29 Identities = 34/110 (30%), Positives = 53/110 (48%), Gaps = 9/110 (8%) Query: 1238 RMAMPEPEWTTVGPELNGLDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPL 1297 R A+PEP T+ PEL + + L + L +L+ L+ +L ELV L PL Sbjct: 32 RAAVPEPAEVTLDPELVAVLAPLEVVLDSELVAVLAPLDTVLDSELV-------AVLAPL 84 Query: 1298 HQAALAERALQNLAPKETPVSGEVLETLGPLVGFLGTESTRQI-PLQILL 1346 + L + LAP +T + E++ L PL L E + PL+++L Sbjct: 85 -EVVLDSEVVAVLAPLDTVLDSELVAVLVPLEVVLDPELVAVLAPLEVVL 133 Score = 31.6 bits (70), Expect = 7.2 Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 9/109 (8%) Query: 1239 MAMPEPEWTTVGPELNGLDSKLLLDLPIQLMDRLSNESIMLVVELVQRAPEQLLALTPLH 1298 +A+ P + PEL + + L + L +L+ L+ ++L ELV L PL Sbjct: 108 VAVLVPLEVVLDPELVAVLAPLEVVLDSELVAVLAPLEVVLDSELVA-------VLAPL- 159 Query: 1299 QAALAERALQNLAPKETPVSGEVLETLGPLVGFLGTE-STRQIPLQILL 1346 + L + LAP E + E++ L PL G L +E T IPL +L Sbjct: 160 EVVLESELVAVLAPLEVVLDSELVAVLAPLEGVLDSELVTVLIPLDTVL 208 >gi|32490559 low density lipoprotein receptor-related protein 10 precursor [Homo sapiens] Length = 713 Score = 37.0 bits (84), Expect = 0.17 Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 6/74 (8%) Query: 126 PRDFLVHQAGVLGGLVEVLLGALVPG-GPPTPTRPPCTRDGPSDCVLAADWLPSLLL--L 182 P L + +L G+V+ L G L+P GPP PTR P GP VLA + +LL L Sbjct: 640 PLPSLPLEPSLLSGVVQALRGRLLPSLGPPGPTRSP---PGPHTAVLALEDEDDVLLVPL 696 Query: 183 LEGTRWQALVQVQP 196 E W A + +P Sbjct: 697 AEPGVWVAEAEDEP 710 >gi|169234951 coiled-coil domain containing 17 [Homo sapiens] Length = 590 Score = 36.6 bits (83), Expect = 0.22 Identities = 69/280 (24%), Positives = 93/280 (33%), Gaps = 25/280 (8%) Query: 898 PAAGLGPGHARHVLRSLVNQSVQDGEEQVRRLGP---LACFLSPEELQSLVPLSDPTGPV 954 P PG +R+L ++DG LG L S ELQ G Sbjct: 201 PVQKANPGTLAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTRRGRAGAT 260 Query: 955 ERGLLECAANGTLSPEGRVAYELLGVLRSSGGAVLSPRELRVWAPLFSQLGLRFLQELSE 1014 L A R+ E+L + G A L P++LR+ Q R L Sbjct: 261 SGELPVVEAENR-----RLEAEILALQMQRGRAPLGPQDLRLLGDASLQPKGRRDPPLLP 315 Query: 1015 PQLRAMLPVLQGTSVTPAQAVLLLGRLLPRHDLSLEELCSLHLLLPGLSPQTLQAIPRRV 1074 P + LP L G S + +L L+ H LLP + L P Sbjct: 316 PPVAPPLPPLPGFSEPQLPGTMT-------RNLGLDS----HFLLP--TSDMLGPAPYDP 362 Query: 1075 LVGACSCLAPELSRLSACQTAALLQTFRVKDGVKNMGTTGAGPAVCIPGQPIPTTWPDC- 1133 G L L A L+T +DG TT PA+C+P P P +C Sbjct: 363 GAGLV-IFYDFLRGLEASWIWVQLRTGLARDGRDTGRTTALPPALCLPPPPAPGPMGNCA 421 Query: 1134 -LLPLLPLKLLQLDSLALLANRRRYWE-LPWSEQQAQFLW 1171 L P+ L S L + W+ L W+ W Sbjct: 422 ILASRQPVPRLPPSSSVSLVCELQVWQGLAWARAPQPKAW 461 >gi|4503657 forkhead box H1 [Homo sapiens] Length = 365 Score = 35.4 bits (80), Expect = 0.50 Identities = 53/220 (24%), Positives = 70/220 (31%), Gaps = 57/220 (25%) Query: 311 SPPPPPA-------LLHCLSTGVPLPRASQPSAHISPRQRRAITVEALCENHLGPAPPYS 363 SPPPPP+ LL G P P + S+ + P EA+ P PP Sbjct: 158 SPPPPPSEGFSIKSLLGGSGEGAPWPGLAPQSSPV-PAGTGNSGEEAV------PTPPLP 210 Query: 364 ISNFSIHLLCQHTKPA-----------------TPQPHPSTTAICQTAVWYAVSWAPGAQ 406 S + LC P +P+P + Q AV + Sbjct: 211 SSERPLWPLCPLPGPTRVEGETVQGGAIGPSTLSPEPRAWPLHLLQGT---AVPGGRSSG 267 Query: 407 GWLQACHDQFPDEFLDAICSNLSFSALSGSNRRLVKRLCAGLLPPPTSCPEGLPPVPLTP 466 G + Q P +L N+ L PPPTSCP+ P T Sbjct: 268 GHRASLWGQLPTSYLPIYTPNVVMP----------------LAPPPTSCPQ----CPSTS 307 Query: 467 DIFWGCFLENETLWAERLCGEASLQAVPPSN---QAWVQH 503 +WG E +A Q VPP+ WV H Sbjct: 308 PAYWGVAPETRGPPGLLCDLDALFQGVPPNKSIYDVWVSH 347 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 35.4 bits (80), Expect = 0.50 Identities = 48/169 (28%), Positives = 67/169 (39%), Gaps = 28/169 (16%) Query: 72 PGRMGE-GPVGEPPPLQPPALRLHDFLVTLRGSPDWEPMLGLLGD--MLALLGQEQTPRD 128 PG G+ GP G+P P+ PP L + ++G P + G +G + + G++ P Sbjct: 795 PGPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP 850 Query: 129 FLVHQAGVLGGLVEVLLGALVPGGPPTPTRPPCTRDGPSDCVLAADWLPSLLLLLEGTRW 188 + G G G+ G P P PP + P A P GT+ Sbjct: 851 PGLDVPGPPGER-----GSPGIPGAPGPIGPPGSPGLPGKA--GASGFP-------GTKG 896 Query: 189 QALVQVQPSVDPTNATGLDGREAAPHF-----LQGLLGLLTPTGELGSK 232 + + P P G+ GR P LQG GL PTGE GSK Sbjct: 897 EMGMMGPPG--PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 35.4 bits (80), Expect = 0.50 Identities = 48/169 (28%), Positives = 67/169 (39%), Gaps = 28/169 (16%) Query: 72 PGRMGE-GPVGEPPPLQPPALRLHDFLVTLRGSPDWEPMLGLLGD--MLALLGQEQTPRD 128 PG G+ GP G+P P+ PP L + ++G P + G +G + + G++ P Sbjct: 795 PGPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP 850 Query: 129 FLVHQAGVLGGLVEVLLGALVPGGPPTPTRPPCTRDGPSDCVLAADWLPSLLLLLEGTRW 188 + G G G+ G P P PP + P A P GT+ Sbjct: 851 PGLDVPGPPGER-----GSPGIPGAPGPIGPPGSPGLPGKA--GASGFP-------GTKG 896 Query: 189 QALVQVQPSVDPTNATGLDGREAAPHF-----LQGLLGLLTPTGELGSK 232 + + P P G+ GR P LQG GL PTGE GSK Sbjct: 897 EMGMMGPPG--PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 35.4 bits (80), Expect = 0.50 Identities = 48/169 (28%), Positives = 67/169 (39%), Gaps = 28/169 (16%) Query: 72 PGRMGE-GPVGEPPPLQPPALRLHDFLVTLRGSPDWEPMLGLLGD--MLALLGQEQTPRD 128 PG G+ GP G+P P+ PP L + ++G P + G +G + + G++ P Sbjct: 795 PGPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP 850 Query: 129 FLVHQAGVLGGLVEVLLGALVPGGPPTPTRPPCTRDGPSDCVLAADWLPSLLLLLEGTRW 188 + G G G+ G P P PP + P A P GT+ Sbjct: 851 PGLDVPGPPGER-----GSPGIPGAPGPIGPPGSPGLPGKA--GASGFP-------GTKG 896 Query: 189 QALVQVQPSVDPTNATGLDGREAAPHF-----LQGLLGLLTPTGELGSK 232 + + P P G+ GR P LQG GL PTGE GSK Sbjct: 897 EMGMMGPPG--PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943 >gi|81158226 neuronal cell adhesion molecule isoform A precursor [Homo sapiens] Length = 1304 Score = 35.4 bits (80), Expect = 0.50 Identities = 41/141 (29%), Positives = 58/141 (41%), Gaps = 28/141 (19%) Query: 209 REAAPHFLQGLLGLLTPTGELGSKEALWGGLLR----TVGAP---LYAAFQEGLL---RV 258 RE P FL TP G +KE L G +L G P +Y A ++G+L R Sbjct: 264 RERPPTFL-------TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRT 316 Query: 259 THSLQDEVFSILGQPEPDT-NGQCQGGNLQQLLLWGVRHNLSWDVQALGFLSGSP----- 312 + ++ I+ E D+ N QC N L + H +S V+A + +P Sbjct: 317 VYKNFEKTLQIIHVSEADSGNYQCIAKN----ALGAIHHTISVRVKAAPYWITAPQNLVL 372 Query: 313 -PPPPALLHCLSTGVPLPRAS 332 P L C + G P PR S Sbjct: 373 SPGEDGTLICRANGNPKPRIS 393 >gi|81158224 neuronal cell adhesion molecule isoform B precursor [Homo sapiens] Length = 1183 Score = 35.4 bits (80), Expect = 0.50 Identities = 41/141 (29%), Positives = 58/141 (41%), Gaps = 28/141 (19%) Query: 209 REAAPHFLQGLLGLLTPTGELGSKEALWGGLLR----TVGAP---LYAAFQEGLL---RV 258 RE P FL TP G +KE L G +L G P +Y A ++G+L R Sbjct: 258 RERPPTFL-------TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRT 310 Query: 259 THSLQDEVFSILGQPEPDT-NGQCQGGNLQQLLLWGVRHNLSWDVQALGFLSGSP----- 312 + ++ I+ E D+ N QC N L + H +S V+A + +P Sbjct: 311 VYKNFEKTLQIIHVSEADSGNYQCIAKN----ALGAIHHTISVRVKAAPYWITAPQNLVL 366 Query: 313 -PPPPALLHCLSTGVPLPRAS 332 P L C + G P PR S Sbjct: 367 SPGEDGTLICRANGNPKPRIS 387 >gi|110611914 progesterone receptor [Homo sapiens] Length = 933 Score = 34.3 bits (77), Expect = 1.1 Identities = 34/113 (30%), Positives = 40/113 (35%), Gaps = 32/113 (28%) Query: 72 PGRMGEGPVGEPPPLQPPAL--RLHDFLVTLRGSPDWEPMLGLLGDMLALLGQEQTPRDF 129 P + P+G PPPL P A R + VT P Sbjct: 411 PAAFPDFPLGPPPPLPPRATPSRPGEAAVTA------------------------APASA 446 Query: 130 LVHQAGVLGGLVEVLL----GALVPGGPPTPTRPPCTRDGPSDCVLAADWLPS 178 V A G +E +L GA GP P PPC G S C+L D LPS Sbjct: 447 SVSSASSSGSTLECILYKAEGAPPQQGPFAP--PPCKAPGASGCLLPRDGLPS 497 >gi|239758021 PREDICTED: hypothetical protein [Homo sapiens] Length = 195 Score = 34.3 bits (77), Expect = 1.1 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 10/66 (15%) Query: 284 GNLQQLLLWGVRHNLSWDVQALGFLSGSPPPPPALLHCLSTGVPLPRASQPSAHISPRQR 343 G LQQ LWG+R WD+ L +L PPPP P QP + P+Q Sbjct: 66 GWLQQSELWGLRR---WDLWRLWWLRQQPPPP-------ELQQPPELEPQPPPELEPQQP 115 Query: 344 RAITVE 349 +T++ Sbjct: 116 PELTLQ 121 >gi|239741335 PREDICTED: hypothetical protein XP_002342177 [Homo sapiens] Length = 214 Score = 34.3 bits (77), Expect = 1.1 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 10/66 (15%) Query: 284 GNLQQLLLWGVRHNLSWDVQALGFLSGSPPPPPALLHCLSTGVPLPRASQPSAHISPRQR 343 G LQQ LWG+R WD+ L +L PPPP P QP + P+Q Sbjct: 66 GWLQQSELWGLRR---WDLWRLWWLRQQPPPP-------ELQQPPELEPQPPPELEPQQP 115 Query: 344 RAITVE 349 +T++ Sbjct: 116 PELTLQ 121 >gi|5032055 reticulon 2 isoform A [Homo sapiens] Length = 545 Score = 34.3 bits (77), Expect = 1.1 Identities = 51/183 (27%), Positives = 73/183 (39%), Gaps = 27/183 (14%) Query: 40 KSLLSTLDQAPQGSLSRSRFFTFLANISSSFEPGRMGEGPVGEPP---PLQPPALRLHDF 96 +S+ DQ PQ SL S + ++S S EPGR G+ P PP PL+ LRL Sbjct: 91 RSVSEPRDQHPQPSLGDS--LESIPSLSQSPEPGRRGD-PDTAPPSERPLEDLRLRLDHL 147 Query: 97 LVTLRGSPDWEPMLGLLGDMLALLGQE-QTPRDFLVHQAG---------VLGGLVEVLLG 146 RG+ E L +E Q P +AG EVL Sbjct: 148 GWVARGTGSGED--SSTSSSTPLEDEEPQEPNRLETGEAGEELDLRLRLAQPSSPEVLTP 205 Query: 147 ALVPG------GPPTPTRPPCTRDGPSDCVLAAD---WLPSLLLLLEGTRWQALVQVQPS 197 L PG G P+P+R + GP + +L + W P + G + Q++ + Sbjct: 206 QLSPGSGTPQAGTPSPSRSRDSNSGPEEPLLEEEEKQWGPLEREPVRGQCLDSTDQLEFT 265 Query: 198 VDP 200 V+P Sbjct: 266 VEP 268 >gi|46255005 reticulon 2 isoform B [Homo sapiens] Length = 472 Score = 34.3 bits (77), Expect = 1.1 Identities = 51/183 (27%), Positives = 73/183 (39%), Gaps = 27/183 (14%) Query: 40 KSLLSTLDQAPQGSLSRSRFFTFLANISSSFEPGRMGEGPVGEPP---PLQPPALRLHDF 96 +S+ DQ PQ SL S + ++S S EPGR G+ P PP PL+ LRL Sbjct: 91 RSVSEPRDQHPQPSLGDS--LESIPSLSQSPEPGRRGD-PDTAPPSERPLEDLRLRLDHL 147 Query: 97 LVTLRGSPDWEPMLGLLGDMLALLGQE-QTPRDFLVHQAG---------VLGGLVEVLLG 146 RG+ E L +E Q P +AG EVL Sbjct: 148 GWVARGTGSGED--SSTSSSTPLEDEEPQEPNRLETGEAGEELDLRLRLAQPSSPEVLTP 205 Query: 147 ALVPG------GPPTPTRPPCTRDGPSDCVLAAD---WLPSLLLLLEGTRWQALVQVQPS 197 L PG G P+P+R + GP + +L + W P + G + Q++ + Sbjct: 206 QLSPGSGTPQAGTPSPSRSRDSNSGPEEPLLEEEEKQWGPLEREPVRGQCLDSTDQLEFT 265 Query: 198 VDP 200 V+P Sbjct: 266 VEP 268 >gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1 [Homo sapiens] Length = 2649 Score = 33.9 bits (76), Expect = 1.4 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 21/103 (20%) Query: 934 CFLSPE--ELQSLVPLSDPT-GPVE-RGLLECAA------------NGTLSPEGRVAYEL 977 C PE E S +PL D + GP++ RG L+C +G +PEGR+ + Sbjct: 1132 CSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRV 1191 Query: 978 LGVLRSSGGAV-----LSPRELRVWAPLFSQLGLRFLQELSEP 1015 LGVL+ + + + R+ P+ + F+ EL +P Sbjct: 1192 LGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDP 1234 >gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2 [Homo sapiens] Length = 2080 Score = 33.9 bits (76), Expect = 1.4 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 21/103 (20%) Query: 934 CFLSPE--ELQSLVPLSDPT-GPVE-RGLLECAA------------NGTLSPEGRVAYEL 977 C PE E S +PL D + GP++ RG L+C +G +PEGR+ + Sbjct: 563 CSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRV 622 Query: 978 LGVLRSSGGAV-----LSPRELRVWAPLFSQLGLRFLQELSEP 1015 LGVL+ + + + R+ P+ + F+ EL +P Sbjct: 623 LGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDP 665 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.138 0.430 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 81,598,106 Number of Sequences: 37866 Number of extensions: 4412582 Number of successful extensions: 15112 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 53 Number of HSP's that attempted gapping in prelim test: 14845 Number of HSP's gapped (non-prelim): 257 length of query: 1775 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1658 effective length of database: 13,817,196 effective search space: 22908910968 effective search space used: 22908910968 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.