BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24308452 WD repeat domain 85 [Homo sapiens] (452 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24308452 WD repeat domain 85 [Homo sapiens] 953 0.0 gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 54 3e-07 gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 54 4e-07 gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 54 4e-07 gi|58331266 WD repeat domain 59 [Homo sapiens] 54 4e-07 gi|4507703 tumor suppressing subtransferable candidate 1 [Homo s... 53 5e-07 gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 49 1e-05 gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 47 3e-05 gi|188219762 denticleless homolog [Homo sapiens] 47 4e-05 gi|217330644 WD repeat domain 12 protein [Homo sapiens] 47 4e-05 gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 45 2e-04 gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 45 2e-04 gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 42 9e-04 gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 42 9e-04 gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 42 9e-04 gi|13376840 WD repeat domain 61 [Homo sapiens] 42 9e-04 gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens] 42 0.001 gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens] 42 0.001 gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens] 42 0.001 gi|65787364 coronin, actin binding protein, 1B [Homo sapiens] 40 0.003 gi|14149734 coronin, actin binding protein, 1B [Homo sapiens] 40 0.003 gi|168229161 coronin 7 [Homo sapiens] 40 0.004 gi|14149696 SEC31 homolog B [Homo sapiens] 40 0.004 gi|13129110 WD repeat domain 77 [Homo sapiens] 40 0.004 gi|62234438 Notchless gene homolog isoform b [Homo sapiens] 40 0.004 gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 40 0.004 gi|118402582 cell division cycle 20 [Homo sapiens] 40 0.006 gi|209969680 Fzr1 protein isoform 1 [Homo sapiens] 39 0.007 gi|209969678 Fzr1 protein isoform 3 [Homo sapiens] 39 0.007 gi|33620742 Fzr1 protein isoform 2 [Homo sapiens] 39 0.007 >gi|24308452 WD repeat domain 85 [Homo sapiens] Length = 452 Score = 953 bits (2463), Expect = 0.0 Identities = 452/452 (100%), Positives = 452/452 (100%) Query: 1 MMGCFALQTVDTELTADSVEWCPLQGCRHLLACGTYQLRRPEDRPAGPQNKGGMEVKEPQ 60 MMGCFALQTVDTELTADSVEWCPLQGCRHLLACGTYQLRRPEDRPAGPQNKGGMEVKEPQ Sbjct: 1 MMGCFALQTVDTELTADSVEWCPLQGCRHLLACGTYQLRRPEDRPAGPQNKGGMEVKEPQ 60 Query: 61 VRLGRLFLYSFNDNNSIHPLVEVQRKDTSAILDMKWCHIPVAGHALLGLADASGSIQLLR 120 VRLGRLFLYSFNDNNSIHPLVEVQRKDTSAILDMKWCHIPVAGHALLGLADASGSIQLLR Sbjct: 61 VRLGRLFLYSFNDNNSIHPLVEVQRKDTSAILDMKWCHIPVAGHALLGLADASGSIQLLR 120 Query: 121 LVESEKSHVLEPLSSLALEEQCLALSLDWSTGKTGRAGDQPLKIISSDSTGQLHLLMVNE 180 LVESEKSHVLEPLSSLALEEQCLALSLDWSTGKTGRAGDQPLKIISSDSTGQLHLLMVNE Sbjct: 121 LVESEKSHVLEPLSSLALEEQCLALSLDWSTGKTGRAGDQPLKIISSDSTGQLHLLMVNE 180 Query: 181 TRPRLQKVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTM 240 TRPRLQKVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTM Sbjct: 181 TRPRLQKVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTM 240 Query: 241 GVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLLLA 300 GVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLLLA Sbjct: 241 GVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLLLA 300 Query: 301 ACMHSGFKILNCQKAMEERQEATVLTSHTLPDSLVYGADWSWLLFRSLQRAPSWSFPSNL 360 ACMHSGFKILNCQKAMEERQEATVLTSHTLPDSLVYGADWSWLLFRSLQRAPSWSFPSNL Sbjct: 301 ACMHSGFKILNCQKAMEERQEATVLTSHTLPDSLVYGADWSWLLFRSLQRAPSWSFPSNL 360 Query: 361 GTKTADLKGASELPTPCHECREDNDGEGHARPQSGMKPLTEGMRKNGTWLQATAATTRDC 420 GTKTADLKGASELPTPCHECREDNDGEGHARPQSGMKPLTEGMRKNGTWLQATAATTRDC Sbjct: 361 GTKTADLKGASELPTPCHECREDNDGEGHARPQSGMKPLTEGMRKNGTWLQATAATTRDC 420 Query: 421 GVNPEEADSAFSLLATCSFYDHALHLWEWEGN 452 GVNPEEADSAFSLLATCSFYDHALHLWEWEGN Sbjct: 421 GVNPEEADSAFSLLATCSFYDHALHLWEWEGN 452 >gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] Length = 425 Score = 53.9 bits (128), Expect = 3e-07 Identities = 36/121 (29%), Positives = 57/121 (47%), Gaps = 3/121 (2%) Query: 202 AFNYWHPEIVYSGGDDGLLRGWDTR--VPGKFLFTSKRHTMGVCSIQSSPHREHILATGS 259 A++ H + S DD L WDTR K HT V + +P+ E ILATGS Sbjct: 233 AWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGS 292 Query: 260 YDEHILLWDTRNMKQPL-ADTPVQGGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEE 318 D+ + LWD RN+K L + ++++ W P + +L ++ + + K EE Sbjct: 293 ADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEE 352 Query: 319 R 319 + Sbjct: 353 Q 353 Score = 42.4 bits (98), Expect = 9e-04 Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Query: 176 LMVNETRPRLQKVASW--QAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLF 233 LM+ +TR S AH E +FN + I+ +G D + WD R L Sbjct: 251 LMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLH 310 Query: 234 TSKRHTMGVCSIQSSPHREHILATGSYDEHILLWD 268 T + H + + SPH E ILA+ D + +WD Sbjct: 311 TFESHKDEIFQVHWSPHNETILASSGTDRRLNVWD 345 >gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo sapiens] Length = 731 Score = 53.5 bits (127), Expect = 4e-07 Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 2/91 (2%) Query: 186 QKVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSI 245 Q+ +Q H+ W FN P+++ SG DD ++ W T + S VC + Sbjct: 504 QRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNS--VASIEAKANVCCV 561 Query: 246 QSSPHREHILATGSYDEHILLWDTRNMKQPL 276 + SP + LA G D + +D RN KQP+ Sbjct: 562 KFSPSSRYHLAFGCADHCVHYYDLRNTKQPI 592 >gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo sapiens] Length = 707 Score = 53.5 bits (127), Expect = 4e-07 Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 2/91 (2%) Query: 186 QKVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSI 245 Q+ +Q H+ W FN P+++ SG DD ++ W T + S VC + Sbjct: 480 QRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNS--VASIEAKANVCCV 537 Query: 246 QSSPHREHILATGSYDEHILLWDTRNMKQPL 276 + SP + LA G D + +D RN KQP+ Sbjct: 538 KFSPSSRYHLAFGCADHCVHYYDLRNTKQPI 568 >gi|58331266 WD repeat domain 59 [Homo sapiens] Length = 974 Score = 53.5 bits (127), Expect = 4e-07 Identities = 28/82 (34%), Positives = 40/82 (48%) Query: 217 DGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPL 276 DG +R WD R P + H + + P EHILAT S D + WD R ++ L Sbjct: 169 DGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSVKFWDYRQPRKYL 228 Query: 277 ADTPVQGGVWRIKWHPFHHHLL 298 P Q VW+ ++ PF + L+ Sbjct: 229 NILPCQVPVWKARYTPFSNGLV 250 Score = 41.2 bits (95), Expect = 0.002 Identities = 42/203 (20%), Positives = 85/203 (41%), Gaps = 20/203 (9%) Query: 139 EEQCLALSLDWSTGKTGRAGDQPLKIISSDSTGQLHLLMVNETRPRLQKVASWQAHQ-FE 197 + Q A+S+D +G + L I++ D+ + H + +++ + V W H F Sbjct: 16 DSQATAMSVDCLGQHAVLSGRRFLYIVNLDAPFEGHRKISRQSKWDIGAV-QWNPHDSFA 74 Query: 198 AWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILAT 257 + AA + ++ Y D G+ T + HT + + + +L T Sbjct: 75 HYFAASSNQRVDL-YKWKDGS----------GEVGTTLQGHTRVISDLDWAVFEPDLLVT 123 Query: 258 GSYDEHILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAME 317 S D +I +WD ++ ++P G ++KW+ + + L A H G + + Sbjct: 124 SSVDTYIYIWDIKDTRKPTVALSAVAGASQVKWNKKNANCL--ATSHDG-----DVRIWD 176 Query: 318 ERQEATVLTSHTLPDSLVYGADW 340 +R+ +T + S ++G DW Sbjct: 177 KRKPSTAVEYLAAHLSKIHGLDW 199 >gi|4507703 tumor suppressing subtransferable candidate 1 [Homo sapiens] Length = 387 Score = 53.1 bits (126), Expect = 5e-07 Identities = 43/164 (26%), Positives = 66/164 (40%), Gaps = 33/164 (20%) Query: 216 DDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTRNMKQP 275 +D LRGWDTR + H V + +P++++ LA+ D + WDTRN+ +P Sbjct: 205 NDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEP 264 Query: 276 LADTPVQG-GVWRIKWHPFHHHLLLAACMHSGFKILNC---------------------- 312 + VW ++++ H L+L S + N Sbjct: 265 VKTLEEHSHWVWNVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDISDQED 324 Query: 313 ----QKAMEERQEATVLTSHTLPDSLVYGADWS----WLLFRSL 348 +K+ E Q+ + T DS VY DWS W LF SL Sbjct: 325 HRSEEKSKEPLQDNVIATYEEHEDS-VYAVDWSSADPW-LFASL 366 >gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] Length = 446 Score = 48.5 bits (114), Expect = 1e-05 Identities = 42/137 (30%), Positives = 60/137 (43%), Gaps = 22/137 (16%) Query: 193 AHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRV--PGKFLFTSKRHTMGVCSIQSSPH 250 AH + + +++ P ++ SGGDDG L+ WD R G + T K+H V S++ P Sbjct: 306 AHDGDVNVISWSRREPFLL-SGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQ 364 Query: 251 REHILATGSYDEHILLWDTRNMKQP----------LADTP-----VQGGVWRIK---WHP 292 + A D I WD + P LAD P V G +K WHP Sbjct: 365 DSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELHWHP 424 Query: 293 FHHHLLLAACMHSGFKI 309 LL++ + SGF I Sbjct: 425 QCPGLLVSTAL-SGFTI 440 Score = 28.9 bits (63), Expect = 10.0 Identities = 20/73 (27%), Positives = 28/73 (38%), Gaps = 11/73 (15%) Query: 224 DTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPLADTPVQG 283 D + K +F+ H ++ SP L TG ++I LW TP G Sbjct: 199 DEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLW-----------TPTDG 247 Query: 284 GVWRIKWHPFHHH 296 G W + PF H Sbjct: 248 GSWHVDQRPFVGH 260 >gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] Length = 323 Score = 47.4 bits (111), Expect = 3e-05 Identities = 41/160 (25%), Positives = 74/160 (46%), Gaps = 13/160 (8%) Query: 146 SLDWSTGKTGRAGDQPLKIISSDSTGQLHLLMVNETRPRLQKVASWQAHQFEAWIAAFNY 205 S+DWS + G+Q + S D T +L V ++ + +++ H+ + ++ Sbjct: 116 SVDWSQTR----GEQLVVSGSWDQTVKLWDPTVGKS------LCTFRGHESIIYSTIWSP 165 Query: 206 WHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHIL 265 P S D LR WD + G + H + S + E++L TG+ D + Sbjct: 166 HIPGCFASASGDQTLRIWDVKAAGVRIVIPA-HQAEILSCDWCKYNENLLVTGAVDCSLR 224 Query: 266 LWDTRNMKQPLADTPVQG-GVWRIKWHPFHHHLLLAACMH 304 WD RN++QP+ + + R+K+ PFH +LA+C + Sbjct: 225 GWDLRNVRQPVFELLGHTYAIRRVKFSPFHAS-VLASCSY 263 Score = 42.7 bits (99), Expect = 7e-04 Identities = 23/76 (30%), Positives = 38/76 (50%) Query: 193 AHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHRE 252 AHQ E + ++ ++ +G D LRGWD R + +F HT + ++ SP Sbjct: 196 AHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHA 255 Query: 253 HILATGSYDEHILLWD 268 +LA+ SYD + W+ Sbjct: 256 SVLASCSYDFTVRFWN 271 Score = 40.8 bits (94), Expect = 0.003 Identities = 34/100 (34%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Query: 171 GQLHLLMVNETRPRLQKVASWQAHQFEA-WIAAFNYWHPEIVYSGGDDGLLRGWDTRVPG 229 G L +L +E RL + W F+ W + N H I SG DG L+ WDT Sbjct: 46 GTLLILDPDEAGLRLFRSFDWNDGLFDVTW--SENNEHVLITCSG--DGSLQLWDTAKAA 101 Query: 230 KFLFTSKRHTMGVCSIQSSPHR-EHILATGSYDEHILLWD 268 L K H V S+ S R E ++ +GS+D+ + LWD Sbjct: 102 GPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWD 141 Score = 34.3 bits (77), Expect = 0.24 Identities = 22/83 (26%), Positives = 35/83 (42%) Query: 186 QKVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSI 245 Q V H + F+ +H ++ S D +R W+ P L T + HT C + Sbjct: 233 QPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGL 292 Query: 246 QSSPHREHILATGSYDEHILLWD 268 S +A S+DE I ++D Sbjct: 293 DFSLQSPTQVADCSWDETIKIYD 315 Score = 31.6 bits (70), Expect = 1.5 Identities = 21/59 (35%), Positives = 26/59 (44%) Query: 218 GLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPL 276 G L D G LF S G+ + S + EH+L T S D + LWDT PL Sbjct: 46 GTLLILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPL 104 >gi|188219762 denticleless homolog [Homo sapiens] Length = 730 Score = 47.0 bits (110), Expect = 4e-05 Identities = 45/155 (29%), Positives = 67/155 (43%), Gaps = 15/155 (9%) Query: 132 PLSSLALEEQCLALSLDWSTGKTGRAGDQPLKIISSDSTGQLHLLMV--NETRPRLQKVA 189 PL SL QC S G+TG P S + H+L V E RL Sbjct: 24 PLQSLLTGYQCSGNDEHTSYGETG-VPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTE 82 Query: 190 SWQAHQ--FEAWIAAFNY-----WHP---EIVYSGGDDGLLRGWDTRVPGKFLFTSKRHT 239 S + F+ W+A +N W P ++V + GD + WD + G+ + T K H Sbjct: 83 SQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQ-TAKFWDVKA-GELIGTCKGHQ 140 Query: 240 MGVCSIQSSPHREHILATGSYDEHILLWDTRNMKQ 274 + S+ S + + TG D +I++WDTR K+ Sbjct: 141 CSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKK 175 >gi|217330644 WD repeat domain 12 protein [Homo sapiens] Length = 423 Score = 47.0 bits (110), Expect = 4e-05 Identities = 28/68 (41%), Positives = 35/68 (51%), Gaps = 2/68 (2%) Query: 213 SGGDDGLLRGWDTRVPGKFLFTSK--RHTMGVCSIQSSPHREHILATGSYDEHILLWDTR 270 SG D +R WD R L + HT V S++ SP E L +GS D + LWDTR Sbjct: 314 SGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTR 373 Query: 271 NMKQPLAD 278 + K PL D Sbjct: 374 SCKAPLYD 381 Score = 40.8 bits (94), Expect = 0.003 Identities = 51/197 (25%), Positives = 77/197 (39%), Gaps = 25/197 (12%) Query: 159 DQPLKIISSDSTGQLHLLMVNETRPRLQK-----------VASWQAHQFEAWIAAFNYWH 207 D+ LKI S+ T + + + RPR ++ + + H EA +++ + Sbjct: 210 DKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHM-EA-VSSVLWSD 267 Query: 208 PEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLW 267 E + S D +R WD G T + + C I SP + LA+GS D HI LW Sbjct: 268 AEEICSASWDHTIRVWDVE-SGSLKSTLTGNKVFNC-ISYSPLCKR-LASGSTDRHIRLW 324 Query: 268 DTRNMKQPLAD---TPVQGGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEERQEATV 324 D R L T G V +KW P H L++ + N K + R Sbjct: 325 DPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLD------NIVKLWDTRSCKAP 378 Query: 325 LTSHTLPDSLVYGADWS 341 L + V DW+ Sbjct: 379 LYDLAAHEDKVLSVDWT 395 >gi|83779014 katanin p80 subunit B 1 [Homo sapiens] Length = 655 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Query: 209 EIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWD 268 E++ +G G +R WD K L T H +CS+ P+ E + A+GS D +I LWD Sbjct: 76 ELIVAGSQSGSIRVWDLEA-AKILRTLMGHKANICSLDFHPYGEFV-ASGSQDTNIKLWD 133 Query: 269 TR 270 R Sbjct: 134 IR 135 Score = 33.9 bits (76), Expect = 0.31 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 8/94 (8%) Query: 213 SGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTRNM 272 S DD ++ WD GK + HT V ++ P+ E++LA+GS D I WD Sbjct: 164 SAADDHTVKLWDLTA-GKMMSEFPGHTGPVNVVEFHPN-EYLLASGSSDRTIRFWDLEKF 221 Query: 273 KQPLADTPVQGGVWRIKWHPFHHHLLLAACMHSG 306 + G V + ++P C++SG Sbjct: 222 QVVSCIEGEPGPVRSVLFNPD------GCCLYSG 249 >gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapiens] Length = 522 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 3/124 (2%) Query: 186 QKVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSI 245 +++ + H + AF+ + +GG D R WD R G+ + + H + I Sbjct: 356 EEILHQEGHSMGVYDIAFHQ-DGSLAGTGGLDAFGRVWDLRT-GRCIMFLEGHLKEIYGI 413 Query: 246 QSSPHREHILATGSYDEHILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLLLAACMHS 305 SP+ HI ATGS D +WD R + Q V +K+ P H + LL + Sbjct: 414 NFSPNGYHI-ATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDN 472 Query: 306 GFKI 309 KI Sbjct: 473 TAKI 476 Score = 30.0 bits (66), Expect = 4.5 Identities = 15/57 (26%), Positives = 26/57 (45%), Gaps = 1/57 (1%) Query: 211 VYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLW 267 + +G D + WD R + ++T H V ++ P + L TG+YD +W Sbjct: 422 IATGSGDNTCKVWDLR-QRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIW 477 >gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sapiens] Length = 390 Score = 42.4 bits (98), Expect = 9e-04 Identities = 26/95 (27%), Positives = 42/95 (44%) Query: 190 SWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSP 249 S AH E +FN + I+ +G D + WD R L + + H + +Q SP Sbjct: 233 SVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSP 292 Query: 250 HREHILATGSYDEHILLWDTRNMKQPLADTPVQGG 284 H E ILA+ D + +WD + + + + G Sbjct: 293 HNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDG 327 Score = 28.9 bits (63), Expect = 10.0 Identities = 20/94 (21%), Positives = 39/94 (41%), Gaps = 13/94 (13%) Query: 187 KVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRV-------------PGKFLF 233 K+ S+++H+ E + ++ + I+ S G D L WD P + LF Sbjct: 274 KLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLF 333 Query: 234 TSKRHTMGVCSIQSSPHREHILATGSYDEHILLW 267 HT + +P+ ++ + S D + +W Sbjct: 334 IHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVW 367 >gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sapiens] Length = 424 Score = 42.4 bits (98), Expect = 9e-04 Identities = 26/95 (27%), Positives = 42/95 (44%) Query: 190 SWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSP 249 S AH E +FN + I+ +G D + WD R L + + H + +Q SP Sbjct: 267 SVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSP 326 Query: 250 HREHILATGSYDEHILLWDTRNMKQPLADTPVQGG 284 H E ILA+ D + +WD + + + + G Sbjct: 327 HNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDG 361 Score = 28.9 bits (63), Expect = 10.0 Identities = 20/94 (21%), Positives = 39/94 (41%), Gaps = 13/94 (13%) Query: 187 KVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRV-------------PGKFLF 233 K+ S+++H+ E + ++ + I+ S G D L WD P + LF Sbjct: 308 KLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLF 367 Query: 234 TSKRHTMGVCSIQSSPHREHILATGSYDEHILLW 267 HT + +P+ ++ + S D + +W Sbjct: 368 IHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVW 401 >gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapiens] Length = 425 Score = 42.4 bits (98), Expect = 9e-04 Identities = 26/95 (27%), Positives = 42/95 (44%) Query: 190 SWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSP 249 S AH E +FN + I+ +G D + WD R L + + H + +Q SP Sbjct: 268 SVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSP 327 Query: 250 HREHILATGSYDEHILLWDTRNMKQPLADTPVQGG 284 H E ILA+ D + +WD + + + + G Sbjct: 328 HNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDG 362 Score = 28.9 bits (63), Expect = 10.0 Identities = 20/94 (21%), Positives = 39/94 (41%), Gaps = 13/94 (13%) Query: 187 KVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLLRGWDTRV-------------PGKFLF 233 K+ S+++H+ E + ++ + I+ S G D L WD P + LF Sbjct: 309 KLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLF 368 Query: 234 TSKRHTMGVCSIQSSPHREHILATGSYDEHILLW 267 HT + +P+ ++ + S D + +W Sbjct: 369 IHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVW 402 >gi|13376840 WD repeat domain 61 [Homo sapiens] Length = 305 Score = 42.4 bits (98), Expect = 9e-04 Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 5/110 (4%) Query: 192 QAHQFEAWIAAFNY---WHPEIVYSGGDDGLLRGWDTRVPGKFL-FTSKRHTMGVCSIQS 247 QAH W A+ + E V +G D L++ W R L ++ + H +GV S+ Sbjct: 13 QAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDI 72 Query: 248 SPHREHILATGSYDEHILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHL 297 S H I A+ S D HI LWD N KQ + W + + P +L Sbjct: 73 S-HTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYL 121 Score = 32.7 bits (73), Expect = 0.69 Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 2/59 (3%) Query: 213 SGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTRN 271 SG DG++ +D GK L T + H M + S+ SP + +L T S D +I ++D ++ Sbjct: 165 SGAIDGIINIFDIAT-GKLLHTLEGHAMPIRSLTFSPDSQ-LLVTASDDGYIKIYDVQH 221 >gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens] Length = 919 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 4/102 (3%) Query: 200 IAAFNYWHPEIVYSGGDDGLLRGWDTRVPG--KFLFTSKRHT-MGVCSIQSSPHREHILA 256 I A W ++ SG D +R WD RVP + + T+ T V S+ P +LA Sbjct: 758 ILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGR-LLA 816 Query: 257 TGSYDEHILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLL 298 TG D +L+D R + + P V +++ P H+LL Sbjct: 817 TGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLL 858 >gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens] Length = 927 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 4/102 (3%) Query: 200 IAAFNYWHPEIVYSGGDDGLLRGWDTRVPG--KFLFTSKRHT-MGVCSIQSSPHREHILA 256 I A W ++ SG D +R WD RVP + + T+ T V S+ P +LA Sbjct: 766 ILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGR-LLA 824 Query: 257 TGSYDEHILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLL 298 TG D +L+D R + + P V +++ P H+LL Sbjct: 825 TGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLL 866 >gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens] Length = 920 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 4/102 (3%) Query: 200 IAAFNYWHPEIVYSGGDDGLLRGWDTRVPG--KFLFTSKRHT-MGVCSIQSSPHREHILA 256 I A W ++ SG D +R WD RVP + + T+ T V S+ P +LA Sbjct: 759 ILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGR-LLA 817 Query: 257 TGSYDEHILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLL 298 TG D +L+D R + + P V +++ P H+LL Sbjct: 818 TGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLL 859 >gi|65787364 coronin, actin binding protein, 1B [Homo sapiens] Length = 489 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 13/111 (11%) Query: 238 HTMGVCSIQSSPHREHILATGSYDEHILLWD--TRNMKQPLADTPV--QGGVWR---IKW 290 HT V I PH + ++A+GS D +++W + PL + V +G R I W Sbjct: 81 HTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAW 140 Query: 291 HPFHHHLLLAACMHSGFKILNCQKAMEERQEATVLTSHTLPDSLVYGADWS 341 HP ++LL+A + I N A E + +L L+Y W+ Sbjct: 141 HPTARNVLLSAGCDNVVLIWNVGTAEE------LYRLDSLHPDLIYNVSWN 185 >gi|14149734 coronin, actin binding protein, 1B [Homo sapiens] Length = 489 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 13/111 (11%) Query: 238 HTMGVCSIQSSPHREHILATGSYDEHILLWD--TRNMKQPLADTPV--QGGVWR---IKW 290 HT V I PH + ++A+GS D +++W + PL + V +G R I W Sbjct: 81 HTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAW 140 Query: 291 HPFHHHLLLAACMHSGFKILNCQKAMEERQEATVLTSHTLPDSLVYGADWS 341 HP ++LL+A + I N A E + +L L+Y W+ Sbjct: 141 HPTARNVLLSAGCDNVVLIWNVGTAEE------LYRLDSLHPDLIYNVSWN 185 >gi|168229161 coronin 7 [Homo sapiens] Length = 925 Score = 40.0 bits (92), Expect = 0.004 Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 11/128 (8%) Query: 202 AFNYWHPEIVYSGGDDGLLRGWDTRVPGKFL---FTSKR-----HTMGVCSIQSSPHREH 253 A++ + P + G+D +R W RVP + L T+ HT +CS++ P + Sbjct: 551 AWDPFDPHRLAVAGEDARIRLW--RVPAEGLEEVLTTPETVLTGHTEKICSLRFHPLAAN 608 Query: 254 ILATGSYDEHILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLLLAACMHSGFKILNCQ 313 +LA+ SYD + +WD + L Q ++ + W P L C ++ + Sbjct: 609 VLASSSYDLTVRIWDLQAGADRLKLQGHQDQIFSLAWSP-DGQQLATVCKDGRVRVYRPR 667 Query: 314 KAMEERQE 321 E QE Sbjct: 668 SGPEPLQE 675 Score = 32.0 bits (71), Expect = 1.2 Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 14/110 (12%) Query: 238 HTMGVCSIQSSPHREHILATGSYDEHILLWDTRNMKQPLADTP--VQG----GVWRIKWH 291 H+ V + SP + +LATGS D + LW Q L P V G V +++H Sbjct: 76 HSDLVTDLDFSPFDDFLLATGSADRTVKLWRLPGPGQALPSAPGVVLGPEDLPVEVLQFH 135 Query: 292 PFHHHLLLAACMHSGFKILNCQKAMEERQEATVLTSHTLPDSLVYGADWS 341 P +L++A + K+ + K +Q T L +H LV A WS Sbjct: 136 PTSDGILVSAA-GTTVKVWDAAK----QQPLTELAAH---GDLVQSAVWS 177 >gi|14149696 SEC31 homolog B [Homo sapiens] Length = 1179 Score = 40.0 bits (92), Expect = 0.004 Identities = 25/102 (24%), Positives = 52/102 (50%), Gaps = 11/102 (10%) Query: 210 IVYSGGDDGLLRGWDTR---VPGK--FLFTSKRHTMGVCSIQSSPHREHILATGSYDEHI 264 ++ GGD+G+L ++ GK + ++HT V ++ +P + ++LA+G+ D I Sbjct: 87 VIVGGGDNGMLILYNVTHILSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEI 146 Query: 265 LLWDTRNMKQPL-----ADTPVQGGVWRIKWHPFHHHLLLAA 301 +WD N+ P+ + P + + + W+ H+L +A Sbjct: 147 FIWDLNNLNVPMTLGSKSQQPPE-DIKALSWNRQAQHILSSA 187 >gi|13129110 WD repeat domain 77 [Homo sapiens] Length = 342 Score = 40.0 bits (92), Expect = 0.004 Identities = 40/170 (23%), Positives = 69/170 (40%), Gaps = 13/170 (7%) Query: 103 GHALLGLADASGSIQL--LRLVESEKSHVLEPLSSLALEEQCLALSLDWSTGKTGRAGDQ 160 G LLG + SG L L + + E S ++ + L W G++ Sbjct: 40 GALLLGASSLSGRCWAGSLWLFKDPCAAPNEGFCSAGVQTEAGVADLTW-------VGER 92 Query: 161 PLKIISSDSTGQLHLLMVNETRPRLQKVASWQAHQFEAWIAAFNYWHPEIVYSGGDDGLL 220 + + S +L L NET + K ++ + ++ + + SG D + Sbjct: 93 GILVASDSGAVELWELDENETLI-VSKFCKYEHDDIVSTVSVLSSGTQAV--SGSKDICI 149 Query: 221 RGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTR 270 + WD L + + H V + +SPH++ + + S D ILLWDTR Sbjct: 150 KVWDL-AQQVVLSSYRAHAAQVTCVAASPHKDSVFLSCSEDNRILLWDTR 198 >gi|62234438 Notchless gene homolog isoform b [Homo sapiens] Length = 193 Score = 40.0 bits (92), Expect = 0.004 Identities = 38/134 (28%), Positives = 56/134 (41%), Gaps = 9/134 (6%) Query: 208 PEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLW 267 PE + SG DD L W K L H + + SP I+A+ S+D+ I LW Sbjct: 49 PERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD-SRIVASASFDKSIKLW 107 Query: 268 DTRNMKQPLADTPVQGGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEERQEATVLTS 327 D R K + V++I W LL++ S K+ + ++ ++ A L Sbjct: 108 DGRTGKYLASLRGHVAAVYQIAWSA-DSRLLVSGSSDSTLKVWD----VKAQKLAMDLPG 162 Query: 328 HTLPDSLVYGADWS 341 H VY DWS Sbjct: 163 HA---DEVYAVDWS 173 >gi|62234461 Notchless gene homolog isoform a [Homo sapiens] Length = 485 Score = 40.0 bits (92), Expect = 0.004 Identities = 38/134 (28%), Positives = 56/134 (41%), Gaps = 9/134 (6%) Query: 208 PEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLW 267 PE + SG DD L W K L H + + SP I+A+ S+D+ I LW Sbjct: 341 PERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD-SRIVASASFDKSIKLW 399 Query: 268 DTRNMKQPLADTPVQGGVWRIKWHPFHHHLLLAACMHSGFKILNCQKAMEERQEATVLTS 327 D R K + V++I W LL++ S K+ + ++ ++ A L Sbjct: 400 DGRTGKYLASLRGHVAAVYQIAWSA-DSRLLVSGSSDSTLKVWD----VKAQKLAMDLPG 454 Query: 328 HTLPDSLVYGADWS 341 H VY DWS Sbjct: 455 HA---DEVYAVDWS 465 Score = 39.3 bits (90), Expect = 0.007 Identities = 55/186 (29%), Positives = 70/186 (37%), Gaps = 35/186 (18%) Query: 213 SGGDDGLLRGWD--TRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHILLWDTR 270 SG D +R WD T P FT K H V SI SP LA+G + ILLWD Sbjct: 131 SGSGDTTVRFWDLSTETPH---FTCKGHRHWVLSISWSPDGRK-LASGCKNGQILLWDPS 186 Query: 271 NMKQPLADTPVQGGVW--RIKWHPFHHH----LLLAACMHSGFKILNCQKAMEERQEATV 324 KQ + T W + W P H + + ++ +I + ER + Sbjct: 187 TGKQ-VGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCER----I 241 Query: 325 LTSHTLP--------DSLVYGAD-------W---SWLLFRSLQRAPSWSFPSNLGTKTAD 366 LT HT D L+Y A W +L R+LQ W L T A Sbjct: 242 LTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYAL 301 Query: 367 LKGASE 372 GA E Sbjct: 302 RTGAFE 307 >gi|118402582 cell division cycle 20 [Homo sapiens] Length = 499 Score = 39.7 bits (91), Expect = 0.006 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 5/97 (5%) Query: 206 WHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKRHTMGVCSIQSSPHREHILATGSYDEHIL 265 W+ I+ SG G + D RV + T H+ VC ++ +P H LA+G D + Sbjct: 276 WNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRH-LASGGNDNLVN 334 Query: 266 LWDTRNMK---QPLAD-TPVQGGVWRIKWHPFHHHLL 298 +W + + PL T QG V + W P+ ++L Sbjct: 335 VWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVL 371 >gi|209969680 Fzr1 protein isoform 1 [Homo sapiens] Length = 496 Score = 39.3 bits (90), Expect = 0.007 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 6/96 (6%) Query: 206 WHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKR---HTMGVCSIQSSPHREHILATGSYDE 262 W+ E + SG D ++ D R P L + +R H VC ++ S + +LA+G D Sbjct: 279 WNAEQLSSGSRDRMILQRDIRTPP--LQSERRLQGHRQEVCGLKWSTDHQ-LLASGGNDN 335 Query: 263 HILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLL 298 +L+W+ ++ T V I W P H LL Sbjct: 336 KLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLL 371 Score = 34.7 bits (78), Expect = 0.18 Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 8/151 (5%) Query: 152 GKTGRAGDQPLKIISSDSTGQLHLLMVNETR-PRLQKVASWQAHQFEAWIAAFNYWHPEI 210 G T R G S + +++ + R P LQ Q H+ E ++ H ++ Sbjct: 269 GHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDH-QL 327 Query: 211 VYSGGDDGLLRGWD-TRVPGKFLFTSKRHTMGVCSIQSSPHREHILAT--GSYDEHILLW 267 + SGG+D L W+ + + +T H V +I SPH+ +LA+ G+ D I W Sbjct: 328 LASGGNDNKLLVWNHSSLSPVQQYTE--HLAAVKAIAWSPHQHGLLASGGGTADRCIRFW 385 Query: 268 DTRNMKQPLADTPVQGGVWRIKWHPFHHHLL 298 +T QPL V + W + L+ Sbjct: 386 NTLT-GQPLQCIDTGSQVCNLAWSKHANELV 415 >gi|209969678 Fzr1 protein isoform 3 [Homo sapiens] Length = 404 Score = 39.3 bits (90), Expect = 0.007 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 6/96 (6%) Query: 206 WHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKR---HTMGVCSIQSSPHREHILATGSYDE 262 W+ E + SG D ++ D R P L + +R H VC ++ S + +LA+G D Sbjct: 190 WNAEQLSSGSRDRMILQRDIRTPP--LQSERRLQGHRQEVCGLKWSTDHQ-LLASGGNDN 246 Query: 263 HILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLL 298 +L+W+ ++ T V I W P H LL Sbjct: 247 KLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLL 282 Score = 34.7 bits (78), Expect = 0.18 Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 8/151 (5%) Query: 152 GKTGRAGDQPLKIISSDSTGQLHLLMVNETR-PRLQKVASWQAHQFEAWIAAFNYWHPEI 210 G T R G S + +++ + R P LQ Q H+ E ++ H ++ Sbjct: 180 GHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDH-QL 238 Query: 211 VYSGGDDGLLRGWD-TRVPGKFLFTSKRHTMGVCSIQSSPHREHILAT--GSYDEHILLW 267 + SGG+D L W+ + + +T H V +I SPH+ +LA+ G+ D I W Sbjct: 239 LASGGNDNKLLVWNHSSLSPVQQYTE--HLAAVKAIAWSPHQHGLLASGGGTADRCIRFW 296 Query: 268 DTRNMKQPLADTPVQGGVWRIKWHPFHHHLL 298 +T QPL V + W + L+ Sbjct: 297 NTLT-GQPLQCIDTGSQVCNLAWSKHANELV 326 >gi|33620742 Fzr1 protein isoform 2 [Homo sapiens] Length = 493 Score = 39.3 bits (90), Expect = 0.007 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 6/96 (6%) Query: 206 WHPEIVYSGGDDGLLRGWDTRVPGKFLFTSKR---HTMGVCSIQSSPHREHILATGSYDE 262 W+ E + SG D ++ D R P L + +R H VC ++ S + +LA+G D Sbjct: 279 WNAEQLSSGSRDRMILQRDIRTPP--LQSERRLQGHRQEVCGLKWSTDHQ-LLASGGNDN 335 Query: 263 HILLWDTRNMKQPLADTPVQGGVWRIKWHPFHHHLL 298 +L+W+ ++ T V I W P H LL Sbjct: 336 KLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLL 371 Score = 34.7 bits (78), Expect = 0.18 Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 8/151 (5%) Query: 152 GKTGRAGDQPLKIISSDSTGQLHLLMVNETR-PRLQKVASWQAHQFEAWIAAFNYWHPEI 210 G T R G S + +++ + R P LQ Q H+ E ++ H ++ Sbjct: 269 GHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDH-QL 327 Query: 211 VYSGGDDGLLRGWD-TRVPGKFLFTSKRHTMGVCSIQSSPHREHILAT--GSYDEHILLW 267 + SGG+D L W+ + + +T H V +I SPH+ +LA+ G+ D I W Sbjct: 328 LASGGNDNKLLVWNHSSLSPVQQYTE--HLAAVKAIAWSPHQHGLLASGGGTADRCIRFW 385 Query: 268 DTRNMKQPLADTPVQGGVWRIKWHPFHHHLL 298 +T QPL V + W + L+ Sbjct: 386 NTLT-GQPLQCIDTGSQVCNLAWSKHANELV 415 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.134 0.434 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,240,030 Number of Sequences: 37866 Number of extensions: 889811 Number of successful extensions: 2842 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 54 Number of HSP's successfully gapped in prelim test: 102 Number of HSP's that attempted gapping in prelim test: 2558 Number of HSP's gapped (non-prelim): 357 length of query: 452 length of database: 18,247,518 effective HSP length: 106 effective length of query: 346 effective length of database: 14,233,722 effective search space: 4924867812 effective search space used: 4924867812 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.