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Search of human proteins with 24307939
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon)
[Homo sapiens]
(541 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom... 1056 0.0
gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ... 348 5e-96
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom... 300 2e-81
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom... 294 1e-79
gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens] 273 4e-73
gi|57863257 T-complex protein 1 isoform a [Homo sapiens] 267 2e-71
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo... 258 7e-69
gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom... 258 1e-68
gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] 251 9e-67
gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom... 250 2e-66
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ... 244 2e-64
gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho... 196 6e-50
gi|7657253 T-complex protein 1 [Homo sapiens] 155 1e-37
gi|57863259 T-complex protein 1 isoform b [Homo sapiens] 144 3e-34
gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom... 131 1e-30
gi|41399285 chaperonin [Homo sapiens] 68 2e-11
gi|31542947 chaperonin [Homo sapiens] 68 2e-11
gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens] 55 1e-07
gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens] 53 8e-07
gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens] 53 8e-07
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 51 2e-06
gi|38044112 restin isoform b [Homo sapiens] 35 0.17
gi|4506751 restin isoform a [Homo sapiens] 35 0.17
gi|110349719 titin isoform N2-A [Homo sapiens] 35 0.23
gi|110349717 titin isoform novex-2 [Homo sapiens] 35 0.23
gi|110349713 titin isoform novex-1 [Homo sapiens] 35 0.23
gi|110349715 titin isoform N2-B [Homo sapiens] 35 0.23
gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1 ... 30 5.6
gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1 pr... 30 5.6
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 30 5.6
>gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo
sapiens]
Length = 541
Score = 1056 bits (2732), Expect = 0.0
Identities = 541/541 (100%), Positives = 541/541 (100%)
Query: 1 MASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKM 60
MASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKM
Sbjct: 1 MASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKM 60
Query: 61 MVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEA 120
MVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEA
Sbjct: 61 MVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEA 120
Query: 121 EQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNS 180
EQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNS
Sbjct: 121 EQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNS 180
Query: 181 CHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMP 240
CHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMP
Sbjct: 181 CHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMP 240
Query: 241 KKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLA 300
KKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLA
Sbjct: 241 KKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLA 300
Query: 301 ICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQ 360
ICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQ
Sbjct: 301 ICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQ 360
Query: 361 EISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVY 420
EISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVY
Sbjct: 361 EISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVY 420
Query: 421 GGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRAR 480
GGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRAR
Sbjct: 421 GGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRAR 480
Query: 481 QVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESE 540
QVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESE
Sbjct: 481 QVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESE 540
Query: 541 E 541
E
Sbjct: 541 E 541
>gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
sapiens]
Length = 539
Score = 348 bits (894), Expect = 5e-96
Identities = 201/505 (39%), Positives = 314/505 (62%), Gaps = 12/505 (2%)
Query: 36 SHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELS 95
S+I AAKAVA+ +RTSLGP G+DKM+ D GDVT+TNDGATIL M V H A+++VELS
Sbjct: 36 SNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELS 95
Query: 96 KSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSV 155
K+QD E GDGTT VV++AG+LL+ +LL +GIHP I++ +++A IE L +S V
Sbjct: 96 KAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPV 155
Query: 156 LVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVAD-MERRDVDFELIKVEGK 214
++ D E L+ +A T+L SKVV+ ++ ++VNAV+ V D VD IK+ K
Sbjct: 156 --ELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKK 213
Query: 215 VGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDY 274
+GG ++D +L++G+++ + S+ + + VE AKI ++ PK +++ V+
Sbjct: 214 LGGTIDDCELVEGLVLTQKVSNSGITR-VEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQM 272
Query: 275 KALQKYEKEKFEEMIQQIKETGANLAICQWGF-----DDEANHLLLQNNLPAVRWVGGPE 329
+ + E+ +++QIK+TG N+ + Q D A H L + + ++ + +
Sbjct: 273 DRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIERED 332
Query: 330 IELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKN-SRAVTIFIR 388
IE I G + V + TA+ LG A L +E++ + K+L I C + + VTI +R
Sbjct: 333 IEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGS-GKLLKITGCASPGKTVTIVVR 391
Query: 389 GGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAM 448
G NK++IEEA+RS+HDALCVIR L++ ++ GGGA EI AL +++ + +E Y +
Sbjct: 392 GSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCV 451
Query: 449 RAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIE 508
RAFADA+EVIP L+EN+G+NPI T+TE+R R + A GI+ G +++ ++ V++
Sbjct: 452 RAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTA-GINVRKGGISNILEELVVQ 510
Query: 509 TLIGKKQQISLATQMVRMILKIDDI 533
L+ ++LAT+ VR ILKIDD+
Sbjct: 511 PLLVSVSALTLATETVRSILKIDDV 535
>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
sapiens]
Length = 545
Score = 300 bits (769), Expect = 2e-81
Identities = 179/535 (33%), Positives = 310/535 (57%), Gaps = 14/535 (2%)
Query: 14 RPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTND 73
RP L++ ++ G + +I AAK +A+ +RT LGP + KM++D G + +TND
Sbjct: 5 RPVLVLSQNTKRES--GRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTND 62
Query: 74 GATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRI 133
G IL + V H AK M+E+S++QD+E+GDGTT V++LAG +L AE L++ +HP +
Sbjct: 63 GNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVV 122
Query: 134 ADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAV 193
Y +A I L KI S+ VDI D++ ++ +++ +K ++ IA++AV
Sbjct: 123 ISAYRKALDDMISTLKKI--SIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 180
Query: 194 LTVADME--RRDVDF-ELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAI 250
V E R+++D + +VE GG +ED+ +++GV+++KD +HP+M + +++ +I +
Sbjct: 181 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 240
Query: 251 LTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEA 310
L E K +++ +++T ED+ + + E+E +++ + I + ++ I + G D A
Sbjct: 241 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 300
Query: 311 NHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGF-AGLVQEISFGTTKD 369
H L++ N+ A+R V + IA A G RIV R EL + +G AGL++ G +
Sbjct: 301 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIG--DE 358
Query: 370 KMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISC 429
I CK+ +A TI +RG +K I+ E +R+L DA+ V RN++ D ++V GGGA+E++
Sbjct: 359 YFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAV 418
Query: 430 ALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPAL 489
A A+++++ +EQ+ RA A ALEVIP L +N G + I+ +T +RA+ +E
Sbjct: 419 AHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETW 478
Query: 490 GIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDI----RKPGESE 540
G++ DMK+ + E L K Q A + ++L+IDDI +K G+ +
Sbjct: 479 GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQ 533
>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
sapiens]
Length = 544
Score = 294 bits (753), Expect = 1e-79
Identities = 178/535 (33%), Positives = 309/535 (57%), Gaps = 15/535 (2%)
Query: 14 RPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTND 73
RP L++ ++ G + +I AAK +A+ +RT LGP + KM++D G + +TND
Sbjct: 5 RPVLVLSQNTKRES--GRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTND 62
Query: 74 GATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRI 133
G IL + V H AK M+E+S++QD+E+GDGTT V++L G +L AE L++ +HP +
Sbjct: 63 GNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPTVV 121
Query: 134 ADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAV 193
Y +A I L KIS + VDI D++ ++ +++ +K ++ IA++AV
Sbjct: 122 ISAYRKALDDMISTLKKIS--IPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 179
Query: 194 LTVADME--RRDVDFE-LIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAI 250
V E R+++D + +VE GG +ED+ +++GV+++KD +HP+M + +++ +I +
Sbjct: 180 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 239
Query: 251 LTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEA 310
L E K +++ +++T ED+ + + E+E +++ + I + ++ I + G D A
Sbjct: 240 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 299
Query: 311 NHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGF-AGLVQEISFGTTKD 369
H L++ N+ A+R V + IA A G RIV R EL + +G AGL++ G +
Sbjct: 300 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD--E 357
Query: 370 KMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISC 429
I CK+ +A TI +RG +K I+ E +R+L DA+ V RN++ D ++V GGGA+E++
Sbjct: 358 YFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAV 417
Query: 430 ALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPAL 489
A A+++++ +EQ+ RA A ALEVIP L +N G + I+ +T +RA+ +E
Sbjct: 418 AHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETW 477
Query: 490 GIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDI----RKPGESE 540
G++ DMK+ + E L K Q A + ++L+IDDI +K G+ +
Sbjct: 478 GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQ 532
>gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
Length = 535
Score = 273 bits (697), Expect = 4e-73
Identities = 172/501 (34%), Positives = 277/501 (55%), Gaps = 12/501 (2%)
Query: 39 MAAKAVANTMRTSLGPNGLDKMMVD--KDGDVTVTNDGATILSMMDVDHQIAKLMVELSK 96
+ A A+ + ++++LGP G+DK+++ +D + VTNDGATIL + VD+ AK++V++S+
Sbjct: 30 IGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSR 89
Query: 97 SQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHL-DKISDSV 155
QDDE+GDGTT V VLA LL EAE L+ + IHP I G+ +A + A E L D
Sbjct: 90 VQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALLSSAVDHG 149
Query: 156 LVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKV 215
++K + L+ A TTL SK++ ++AV AVL + + + E I + K+
Sbjct: 150 SDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRL----KGSGNLEAIHIIKKL 205
Query: 216 GGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKT-KHKLDVTSVEDY 274
GG L D+ L +G ++DK Q PK++E+AKI I + K K ++ V S
Sbjct: 206 GGSLADSYLDEGFLLDKKIGVNQ-PKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKV 264
Query: 275 KALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIA 334
++ EKEK +E +++I + G N I + + L + A+ +E +A
Sbjct: 265 AEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLA 324
Query: 335 IATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMI 394
+ TGG I F KLG L++E+ G +DK++ A TI +RG + I
Sbjct: 325 LVTGGEIASTFDHPELVKLGSCKLIEEVMIG--EDKLIHFSGVALGEACTIVLRGATQQI 382
Query: 395 IEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADA 454
++EA+RSLHDALCV+ ++D+R VYGGG +E+ A AV+Q A++ P E AM ++A A
Sbjct: 383 LDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKA 442
Query: 455 LEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKK 514
L ++P +++N+G + + ++RA E N G+D DM + E+ K+
Sbjct: 443 LRMLPTIIADNAGYDSADLVAQLRAAH-SEGNTTAGLDMREGTIGDMAILGITESFQVKR 501
Query: 515 QQISLATQMVRMILKIDDIRK 535
Q + A + +IL++D+I K
Sbjct: 502 QVLLSAAEAAEVILRVDNIIK 522
>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
Length = 556
Score = 267 bits (683), Expect = 2e-71
Identities = 171/524 (32%), Positives = 290/524 (55%), Gaps = 26/524 (4%)
Query: 32 EALKS-HIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKL 90
E ++S ++MAA ++AN +++SLGP GLDKM+VD GDVT+TNDGATIL +++V+H AK+
Sbjct: 15 ETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKV 74
Query: 91 MVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDK 150
+ EL+ QD E+GDGTT VV++A LL+ A++L+ + IHP + GY A + A+ +
Sbjct: 75 LCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRY--- 131
Query: 151 ISDSVLVDIKD--TEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDV---- 204
I+++++V+ + + LI AKT++ SK++ A + V+AVL + + R
Sbjct: 132 INENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYP 191
Query: 205 --DFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKT 262
++K G+ ++ LI G ++ MPK++ +AKIA L + K K
Sbjct: 192 VNSVNILKAHGR---SQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKL 248
Query: 263 KHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAV 322
++ +T E +++ E + +E IQ+I TGAN+ + G DD ++ AV
Sbjct: 249 GVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAV 308
Query: 323 RWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLV----QEISFGTTKDKMLVIEQCK 378
R V +++ IA A+G I+ + L E+ A ++ + + D++++I+ K
Sbjct: 309 RRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTK 368
Query: 379 NSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEAD 438
+ +I +RG N + +E +RSLHDALCV++ ++ VV GGGA E + ++ + A
Sbjct: 369 ARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYAT 428
Query: 439 KCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRA-RQVKEMNPA------LGI 491
+ EQ A+ FA +L VIP L+ N+ + + ++RA ++NP +G+
Sbjct: 429 SMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGL 488
Query: 492 DCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRK 535
D + D KQ V E I K + + AT+ IL+IDD+ K
Sbjct: 489 DLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532
>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
sapiens]
Length = 543
Score = 258 bits (660), Expect = 7e-69
Identities = 157/526 (29%), Positives = 286/526 (54%), Gaps = 14/526 (2%)
Query: 15 PFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDG 74
P +++K+ S+ G+ L S+I A + +A +RT+LGP G+DK++VD G T++NDG
Sbjct: 5 PVILLKEGTDSSQ--GIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDG 62
Query: 75 ATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIA 134
ATIL ++DV H AK +V+++KSQD E+GDGTT V +LA L++ + ++ G+HP I
Sbjct: 63 ATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIII 122
Query: 135 DGYEQAARVAIEHLDKISDSV--LVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNA 192
+ A ++A+ + +I+ +V ++ + L + A T L SK+++ A++ V+A
Sbjct: 123 RAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDA 182
Query: 193 VLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSH---PQMPKKVEDAKIA 249
V+ + D+ + ++I ++ GG LED++L+ GV K FS+ PKK + KIA
Sbjct: 183 VMMLDDL----LQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIA 238
Query: 250 ILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDE 309
+L E K ++ V +VEDY+A+ E + +++I +GA + + + D
Sbjct: 239 LLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDV 298
Query: 310 ANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKD 369
A ++ V +++ +A GG I + L+A+ LG + +E G +
Sbjct: 299 ATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIG--GE 356
Query: 370 KMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISC 429
+ C ++ T +RGG + +EE +RSLHDA+ ++R I+++ VV GGGA E+
Sbjct: 357 RYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMEL 416
Query: 430 ALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPAL 489
+ + + P +Q + A+A ALE+IP L +N+G + + ++RAR +
Sbjct: 417 SKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHA-QGGTWY 475
Query: 490 GIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRK 535
G+D ++ D + V E + + ++ A++ +I+ +D+ K
Sbjct: 476 GVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIK 521
>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
sapiens]
Length = 507
Score = 258 bits (658), Expect = 1e-68
Identities = 155/468 (33%), Positives = 272/468 (58%), Gaps = 12/468 (2%)
Query: 81 MDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQA 140
+ V H AK M+E+S++QD+E+GDGTT V++LAG +L AE L++ +HP + Y +A
Sbjct: 32 IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKA 91
Query: 141 ARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADME 200
I L KIS + VDI D++ ++ +++ +K ++ IA++AV V E
Sbjct: 92 LDDMISTLKKIS--IPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE 149
Query: 201 --RRDVDFE-LIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEP 257
R+++D + +VE GG +ED+ +++GV+++KD +HP+M + +++ +I +L E
Sbjct: 150 NGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEY 209
Query: 258 PKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQN 317
K +++ +++T ED+ + + E+E +++ + I + ++ I + G D A H L++
Sbjct: 210 KKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRA 269
Query: 318 NLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGF-AGLVQEISFGTTKDKMLVIEQ 376
N+ A+R V + IA A G RIV R EL + +G AGL++ G + I
Sbjct: 270 NITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD--EYFTFITD 327
Query: 377 CKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQE 436
CK+ +A TI +RG +K I+ E +R+L DA+ V RN++ D ++V GGGA+E++ A A++++
Sbjct: 328 CKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEK 387
Query: 437 ADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHK 496
+ +EQ+ RA A ALEVIP L +N G + I+ +T +RA+ +E G++
Sbjct: 388 SKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETG 447
Query: 497 GTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDI----RKPGESE 540
DMK+ + E L K Q A + ++L+IDDI +K G+ +
Sbjct: 448 TLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQ 495
>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
Length = 530
Score = 251 bits (642), Expect = 9e-67
Identities = 168/519 (32%), Positives = 280/519 (53%), Gaps = 22/519 (4%)
Query: 33 ALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMV 92
AL +I AA+ + + +RT+LGP G KM+V GD+ +T DG +L M + H A L+
Sbjct: 19 ALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIA 78
Query: 93 ELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKIS 152
+++ +QDD GDGTT V++ G LL++A+ + G+HP IA+G+E A A+E L+++
Sbjct: 79 KVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEV- 137
Query: 153 DSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDF---ELI 209
V ++K + L+ A+T+L +KV + E+ V++VL V +D E++
Sbjct: 138 -KVTKEMK-RKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR-RPGYPIDLFMVEIM 194
Query: 210 KVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVT 269
+++ K+G DTKLI+G+++D HP M K+VEDA I I E K +
Sbjct: 195 EMKHKLG---TDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYK 251
Query: 270 SVEDYKALQKYEKEKFEEMIQQI---------KETGANLAICQWGFDDEANHLLLQNNLP 320
+ E+ + L K E++ E+ +Q+I + + I Q G D + L ++ +
Sbjct: 252 TAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIV 311
Query: 321 AVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNS 380
A+R +E +++A GG V F +LT + LG AGLV E + G ++K IE+C N
Sbjct: 312 ALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLG--EEKFTFIEECVNP 369
Query: 381 RAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC 440
+VT+ ++G NK + + K ++ D L I+N I D +V G GA E++ A A+ +
Sbjct: 370 CSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSI 429
Query: 441 PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTND 500
+ ++AFADAL +IP L++N+G +P +T+ +V+A V E +G+D
Sbjct: 430 KGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHV-ESKQLVGVDLNTGEPMV 488
Query: 501 MKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGES 539
V + KKQ + T + IL +D+I + G S
Sbjct: 489 AADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMS 527
>gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo
sapiens]
Length = 531
Score = 250 bits (639), Expect = 2e-66
Identities = 164/519 (31%), Positives = 276/519 (53%), Gaps = 22/519 (4%)
Query: 33 ALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMV 92
AL +I AA+ + + +RT+LGP G KM+V GD+ +T DG +L M + H A L+
Sbjct: 19 ALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIA 78
Query: 93 ELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKIS 152
+++ +QDD GDGTT V++ G LL++A+ + G+HP I +G+E A A++ L+++
Sbjct: 79 KVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVK 138
Query: 153 DSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVL-TVADMERRD--VDFELI 209
S + D E LI A+T+L +KV H ++A++ AV+ ++ ++++D +D +I
Sbjct: 139 VSREM---DRETLIDVARTSLRTKV----HAELADVLTEAVVDSILAIKKQDEPIDLFMI 191
Query: 210 KVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVT 269
++ DT LI+G+++D HP M K+VEDA I E K +
Sbjct: 192 EIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYK 251
Query: 270 SVEDYKALQKYEKEKFEEMIQQIKETGAN---------LAICQWGFDDEANHLLLQNNLP 320
S E+ + L K E++ E+ +++I E + I Q G D + L + +
Sbjct: 252 SAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIV 311
Query: 321 AVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNS 380
A+R +E + +A GG + F +L+ + LG AGLV E + G ++K IE+C N
Sbjct: 312 ALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLG--EEKFTFIEKCNNP 369
Query: 381 RAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC 440
R+VT+ I+G NK + + K ++ D L ++N I D VV G GA E++ A A+ +
Sbjct: 370 RSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSV 429
Query: 441 PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTND 500
Q ++AFADAL +IP L++NSG + +T+ +++A E +G+D
Sbjct: 430 KGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEH-SESGQLVGVDLNTGEPMV 488
Query: 501 MKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGES 539
+ V + KKQ + T + IL +D+I + G S
Sbjct: 489 AAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMS 527
>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
sapiens]
Length = 548
Score = 244 bits (622), Expect = 2e-64
Identities = 161/504 (31%), Positives = 265/504 (52%), Gaps = 8/504 (1%)
Query: 32 EALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLM 91
EA+ +I A K +A T RT+ GPNG++KM+++ + VTND ATIL ++V H AK++
Sbjct: 27 EAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMI 86
Query: 92 VELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKI 151
V S Q+ E+GDGT V+V AGALLE AE+LL G+ + +GYE A R A E L +
Sbjct: 87 VMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPNL 146
Query: 152 SDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKV 211
+++D + + +T++ SK + IA V D +VD I+V
Sbjct: 147 VCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLAKLIAQACVSIFPDSGHFNVD--NIRV 204
Query: 212 EGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSV 271
+G + + ++ G++ K+ V+DAKIA+ +CPF+ +TK + + +
Sbjct: 205 CKILGSGISSSSVLHGMVFKKETEGD--VTSVKDAKIAVYSCPFDGMITETKGTVLIKTA 262
Query: 272 EDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIE 331
E+ K E+ + ++ I +TGAN+ + D A H + N+ VR ++
Sbjct: 263 EELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLR 322
Query: 332 LIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAV-TIFIRGG 390
+ G +PR + E++G V G T +++V + K A+ TI +RG
Sbjct: 323 RLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDT--QVVVFKHEKEDGAISTIVLRGS 380
Query: 391 NKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRA 450
++++ +R++ D + + L RD R+V GGGA EI A ++ + CP LEQYA++
Sbjct: 381 TDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKK 440
Query: 451 FADALEVIPMALSENSGMNPIQTMTEVRA-RQVKEMNPALGIDCLHKGTNDMKQQHVIET 509
FA+A E IP AL+ENSG+ + ++++ A Q N L I+ DM + +++T
Sbjct: 441 FAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGILDT 500
Query: 510 LIGKKQQISLATQMVRMILKIDDI 533
+GK I LAT +L++D I
Sbjct: 501 YLGKYWAIKLATNAAVTVLRVDQI 524
>gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo
sapiens]
Length = 486
Score = 196 bits (497), Expect = 6e-50
Identities = 148/519 (28%), Positives = 248/519 (47%), Gaps = 67/519 (12%)
Query: 33 ALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMV 92
AL +I AA+ + + +RT+LGP G KM+V GD+ +T DG +L M
Sbjct: 19 ALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEM----------- 67
Query: 93 ELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKIS 152
G+HP I +G+E A A++ L+++
Sbjct: 68 ----------------------------------GLHPRIITEGFEAAKEKALQFLEEVK 93
Query: 153 DSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVL-TVADMERRD--VDFELI 209
S +D E LI A+T+L +KV H ++A++ AV+ ++ ++++D +D +I
Sbjct: 94 VSREMD---RETLIDVARTSLRTKV----HAELADVLTEAVVDSILAIKKQDEPIDLFMI 146
Query: 210 KVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVT 269
++ DT LI+G+++D HP M K+VEDA I E K +
Sbjct: 147 EIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYK 206
Query: 270 SVEDYKALQKYEKEKFEEMIQQIKETGANLA---------ICQWGFDDEANHLLLQNNLP 320
S E+ + L K E++ E+ +++I E + I Q G D + L + +
Sbjct: 207 SAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIV 266
Query: 321 AVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNS 380
A+R +E + +A GG + F +L+ + LG AGLV E + G ++K IE+C N
Sbjct: 267 ALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLG--EEKFTFIEKCNNP 324
Query: 381 RAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC 440
R+VT+ I+G NK + + K ++ D L ++N I D VV G GA E++ A A+ +
Sbjct: 325 RSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSV 384
Query: 441 PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTND 500
Q ++AFADAL +IP L++NSG + +T+ +++A E +G+D
Sbjct: 385 KGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEH-SESGQLVGVDLNTGEPMV 443
Query: 501 MKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGES 539
+ V + KKQ + T + IL +D+I + G S
Sbjct: 444 AAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMS 482
>gi|7657253 T-complex protein 1 [Homo sapiens]
Length = 557
Score = 155 bits (391), Expect = 1e-37
Identities = 123/502 (24%), Positives = 232/502 (46%), Gaps = 16/502 (3%)
Query: 34 LKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVE 93
L S + A + +A+ +R GP+G K +V G+ T IL ++++H A L+ E
Sbjct: 33 LLSSLAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLRE 92
Query: 94 LSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISD 153
++Q + GDGT VV+L ALLE+AEQLL G+ ++ + Y A + L ++
Sbjct: 93 AGQTQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVLATLPSLAI 152
Query: 154 SVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEG 213
L ++D + + T ++ + ++ +A + +++ E + V
Sbjct: 153 QSLGPLEDPSWALHSVMNTHTLSPMD----HLTKLVAHACWAIKELD-GSFKPERVGVCA 207
Query: 214 KVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVED 273
GG LED+ L+ G+ + QM + A++A+ CPF P P ++S D
Sbjct: 208 LPGGTLEDSCLLPGLAISGKLC-GQMATVLSGARVALFACPFGPAHPNAPATARLSSPAD 266
Query: 274 YKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELI 333
K + E+ + Q+ G N+A+ D+E L + + ++ EI +
Sbjct: 267 LAQFSKGSDQLLEKQVGQLAAAGINVAVVLGEVDEETLTLADKYGIVVIQARSWMEIIYL 326
Query: 334 AIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVI--EQCKNSRAVTIFIRGGN 391
+ ++PR L ++ G V G D + V+ +C + A+T+ +RG
Sbjct: 327 SEVLDTPLLPRL--LPPQRPGKCQRVYRQELG---DGLAVVFEWECTGTPALTVVLRGAT 381
Query: 392 KMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAF 451
+ A+++++ + L +D R++ G GA E++ A +S + + A AF
Sbjct: 382 TQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMALAKMLSDKGSRLEGPSGPAFLAF 441
Query: 452 ADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLI 511
A AL+ +P L+EN+G+ M E+ + N +G+ +G ++ Q+ V +TLI
Sbjct: 442 AWALKYLPKTLAENAGLAVSDVMAEMSGVH-QGGNLLMGVGT--EGIINVAQEGVWDTLI 498
Query: 512 GKKQQISLATQMVRMILKIDDI 533
K Q ++V ++ +D+I
Sbjct: 499 VKAQGFRAVAEVVLQLVTVDEI 520
>gi|57863259 T-complex protein 1 isoform b [Homo sapiens]
Length = 401
Score = 144 bits (362), Expect = 3e-34
Identities = 106/380 (27%), Positives = 186/380 (48%), Gaps = 20/380 (5%)
Query: 173 LGSKVVNSCHRQMAEIAVNAVLTVADMERRDV------DFELIKVEGKVGGRLEDTKLIK 226
+ SK++ A + V+AVL + + R ++K G+ ++ LI
Sbjct: 1 MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGR---SQMESMLIS 57
Query: 227 GVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFE 286
G ++ MPK++ +AKIA L + K K ++ +T E +++ E + +
Sbjct: 58 GYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITK 117
Query: 287 EMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFS 346
E IQ+I TGAN+ + G DD ++ AVR V +++ IA A+G I+ +
Sbjct: 118 ERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLA 177
Query: 347 ELTAEKLGFAGLVQE----ISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSL 402
L E+ A ++ + + D++++I+ K + +I +RG N + +E +RSL
Sbjct: 178 NLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSL 237
Query: 403 HDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMAL 462
HDALCV++ ++ VV GGGA E + ++ + A + EQ A+ FA +L VIP L
Sbjct: 238 HDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTL 297
Query: 463 SENSGMNPIQTMTEVRA-RQVKEMNPA------LGIDCLHKGTNDMKQQHVIETLIGKKQ 515
+ N+ + + ++RA ++NP +G+D + D KQ V E I K +
Sbjct: 298 AVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVK 357
Query: 516 QISLATQMVRMILKIDDIRK 535
+ AT+ IL+IDD+ K
Sbjct: 358 SLKFATEAAITILRIDDLIK 377
>gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo
sapiens]
Length = 339
Score = 131 bits (330), Expect = 1e-30
Identities = 85/318 (26%), Positives = 157/318 (49%), Gaps = 6/318 (1%)
Query: 221 DTKLIKGVIVDKDFSHP---QMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKAL 277
D++L+ GV K FS+ PKK + KIA+L E K ++ V +VEDY+A+
Sbjct: 3 DSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEIRVHTVEDYQAI 62
Query: 278 QKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIAT 337
E + +++I +GA + + + D A ++ V +++ +A
Sbjct: 63 VDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMAC 122
Query: 338 GGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEE 397
GG I + L+A+ LG + +E G + C ++ T +RGG + +EE
Sbjct: 123 GGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFT--GCPKAKTCTFILRGGAEQFMEE 180
Query: 398 AKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEV 457
+RSLHDA+ ++R I+++ VV GGGA E+ + + + P +Q + A+A ALE+
Sbjct: 181 TERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEI 240
Query: 458 IPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQI 517
IP L +N+G + + ++RAR + G+D ++ D + V E + + +
Sbjct: 241 IPRQLCDNAGFDATNILNKLRARHA-QGGTWYGVDINNEDIADNFEAFVWEPAMVRINAL 299
Query: 518 SLATQMVRMILKIDDIRK 535
+ A++ +I+ +D+ K
Sbjct: 300 TAASEAACLIVSVDETIK 317
>gi|41399285 chaperonin [Homo sapiens]
Length = 573
Score = 68.2 bits (165), Expect = 2e-11
Identities = 107/537 (19%), Positives = 205/537 (38%), Gaps = 107/537 (19%)
Query: 30 GLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQI-- 87
G +A + +A+ + ++GP G ++ G VT DG T+ +D+ +
Sbjct: 33 GADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKN 92
Query: 88 --AKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAI 145
AKL+ +++ + ++E GDGTT VLA ++ +E + + +G +P+ I G A I
Sbjct: 93 IGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVI 152
Query: 146 EHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVD 205
L K S V + + + T ++ N M ++ V+TV D + +
Sbjct: 153 AELKKQSKPVTTPEEIAQ--VATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLN-- 208
Query: 206 FELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHK 265
++ ++I+G+ D+ + P + K C F+
Sbjct: 209 --------------DELEIIEGMKFDRGYISPYFINTSKGQK-----CEFQ--------- 240
Query: 266 LDVTSVEDYKALQKYEKEKFEEMIQQIKETGAN---LAICQWGFDDEANHLLLQNNLP-- 320
+ Y L + + + ++ ++ A+ L I D EA L+ N L
Sbjct: 241 ------DAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVG 294
Query: 321 ----AVRWVG-----GPEIELIAIATGGRI------VPRFSELTAEKLGFAGLVQEISFG 365
AV+ G +++ +AIATGG + ++ LG G V
Sbjct: 295 LQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEV----IV 350
Query: 366 TTKDKML----------------VIEQ-----------------CKNSRAVTIFIRGGNK 392
T D ML +IEQ K S V + GG
Sbjct: 351 TKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTS 410
Query: 393 MI-IEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAF 451
+ + E K + DAL R + + +V GGG A + C A+ ++ +
Sbjct: 411 DVEVNEKKDRVTDALNATRAAVEEG-IVLGGGCALLRCIPAL-DSLTPANEDQKIGIEII 468
Query: 452 ADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIE 508
L++ M +++N+G+ + ++ + + +G D + +M ++ +I+
Sbjct: 469 KRTLKIPAMTIAKNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIID 520
>gi|31542947 chaperonin [Homo sapiens]
Length = 573
Score = 68.2 bits (165), Expect = 2e-11
Identities = 107/537 (19%), Positives = 205/537 (38%), Gaps = 107/537 (19%)
Query: 30 GLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQI-- 87
G +A + +A+ + ++GP G ++ G VT DG T+ +D+ +
Sbjct: 33 GADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKN 92
Query: 88 --AKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAI 145
AKL+ +++ + ++E GDGTT VLA ++ +E + + +G +P+ I G A I
Sbjct: 93 IGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVI 152
Query: 146 EHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVD 205
L K S V + + + T ++ N M ++ V+TV D + +
Sbjct: 153 AELKKQSKPVTTPEEIAQ--VATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLN-- 208
Query: 206 FELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHK 265
++ ++I+G+ D+ + P + K C F+
Sbjct: 209 --------------DELEIIEGMKFDRGYISPYFINTSKGQK-----CEFQ--------- 240
Query: 266 LDVTSVEDYKALQKYEKEKFEEMIQQIKETGAN---LAICQWGFDDEANHLLLQNNLP-- 320
+ Y L + + + ++ ++ A+ L I D EA L+ N L
Sbjct: 241 ------DAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVG 294
Query: 321 ----AVRWVG-----GPEIELIAIATGGRI------VPRFSELTAEKLGFAGLVQEISFG 365
AV+ G +++ +AIATGG + ++ LG G V
Sbjct: 295 LQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEV----IV 350
Query: 366 TTKDKML----------------VIEQ-----------------CKNSRAVTIFIRGGNK 392
T D ML +IEQ K S V + GG
Sbjct: 351 TKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTS 410
Query: 393 MI-IEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAF 451
+ + E K + DAL R + + +V GGG A + C A+ ++ +
Sbjct: 411 DVEVNEKKDRVTDALNATRAAVEEG-IVLGGGCALLRCIPAL-DSLTPANEDQKIGIEII 468
Query: 452 ADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIE 508
L++ M +++N+G+ + ++ + + +G D + +M ++ +I+
Sbjct: 469 KRTLKIPAMTIAKNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIID 520
>gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
Length = 723
Score = 55.5 bits (132), Expect = 1e-07
Identities = 80/427 (18%), Positives = 170/427 (39%), Gaps = 39/427 (9%)
Query: 26 SRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDH 85
S + ++K+ + A+ + + +GP G + G+V ++ +G +L + ++H
Sbjct: 3 SSMAAAGSVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEH 62
Query: 86 QIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIAD------GYEQ 139
IA+++V+ S + GDG ++ LL + DR P+ + ++
Sbjct: 63 PIARMIVDCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHWKN 122
Query: 140 AAR----------VAIEHLDKISD--------SVLVDIKDTEPLIQTAKTTLGS----KV 177
+R + LD I D S+ K+ + + L + +V
Sbjct: 123 CSRWKFISQALLTFQTQILDGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCGRV 182
Query: 178 VNSCHRQMAEIAVNAVLTVADMERRDVDFELIK---VE---GKVGGRLEDTKLIKGVIVD 231
+ H+ ++++ + + FEL+ VE G G + D+++I G+++
Sbjct: 183 GRNNHKFISQLMCDYFFKCMTCKSGIGVFELVDDHFVELNVGVTGLPVSDSRIIAGLVLQ 242
Query: 232 KDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQ 291
KDFS + D ++ I+T +P + + + S ++ Q + EK + +++
Sbjct: 243 KDFSVYRPAD--GDMRMVIVTETIQPLFSTSGSEFILNSEAQFQTSQFWIMEKTKAIMKH 300
Query: 292 IKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATG-GRIVP--RFSEL 348
+ L I D ++ N + V + E+ LI G VP FS+
Sbjct: 301 LHSQNVKLLISSVKQPDLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAFSQC 360
Query: 349 TAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCV 408
+ + + + L + +I + G +IE+ + +LH AL +
Sbjct: 361 EIPNTALVKFCKPLILRSKRYVHLGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGALKM 420
Query: 409 IRNLIRD 415
+R L +D
Sbjct: 421 LRQLFKD 427
>gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 52.8 bits (125), Expect = 8e-07
Identities = 89/467 (19%), Positives = 178/467 (38%), Gaps = 37/467 (7%)
Query: 25 KSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGD-VTVTNDGATILSMMDV 83
KS + E +++ + K + + GP+G K + + G V T+ + +LS + V
Sbjct: 13 KSEPLTTERVRTTLSVLKRIVTSC---YGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLV 69
Query: 84 DHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARV 143
H I K++ ++ D +L L+E ++L G+ P + + +
Sbjct: 70 THPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSL 126
Query: 144 AIEHL--DKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAE-----IAVNAVLTV 196
I +L + + VD T+ L+ ++ L SK R+ E I +LT+
Sbjct: 127 CISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTI 186
Query: 197 ADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMP-----KKVEDAKIAIL 251
+ + + G R+ D+ ++ G+++ + S Q+ KK K+A+
Sbjct: 187 PENAEGHIILGKSLIVPLKGQRVIDSTVLPGILI--EMSEVQLMRLLPIKKSTALKVALF 244
Query: 252 TCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEAN 311
T V S +L+ ++ + +Q+ +L +CQ
Sbjct: 245 CTTLSGDTSDTGEGTVVVSYG--VSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLK 302
Query: 312 HLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKM 371
L + + A+ +G +E + TG + + + G V FG+
Sbjct: 303 QFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFH 362
Query: 372 LVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCAL 431
L+ + + ++ + N +E K + AL V++ +++ + GGG E A
Sbjct: 363 LIPNE---ATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAA 419
Query: 432 AVSQEA----------DKCPTLE-QYAMRAFADALEVIPMALSENSG 467
+ + D+C E Q AF ALE + +L + G
Sbjct: 420 YIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGG 466
>gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 52.8 bits (125), Expect = 8e-07
Identities = 89/467 (19%), Positives = 178/467 (38%), Gaps = 37/467 (7%)
Query: 25 KSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGD-VTVTNDGATILSMMDV 83
KS + E +++ + K + + GP+G K + + G V T+ + +LS + V
Sbjct: 13 KSEPLTTERVRTTLSVLKRIVTSC---YGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLV 69
Query: 84 DHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARV 143
H I K++ ++ D +L L+E ++L G+ P + + +
Sbjct: 70 THPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSL 126
Query: 144 AIEHL--DKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAE-----IAVNAVLTV 196
I +L + + VD T+ L+ ++ L SK R+ E I +LT+
Sbjct: 127 CISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTI 186
Query: 197 ADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMP-----KKVEDAKIAIL 251
+ + + G R+ D+ ++ G+++ + S Q+ KK K+A+
Sbjct: 187 PENAEGHIILGKSLIVPLKGQRVIDSTVLPGILI--EMSEVQLMRLLPIKKSTALKVALF 244
Query: 252 TCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEAN 311
T V S +L+ ++ + +Q+ +L +CQ
Sbjct: 245 CTTLSGDTSDTGEGTVVVSYG--VSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLK 302
Query: 312 HLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKM 371
L + + A+ +G +E + TG + + + G V FG+
Sbjct: 303 QFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFH 362
Query: 372 LVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCAL 431
L+ + + ++ + N +E K + AL V++ +++ + GGG E A
Sbjct: 363 LIPNE---ATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAA 419
Query: 432 AVSQEA----------DKCPTLE-QYAMRAFADALEVIPMALSENSG 467
+ + D+C E Q AF ALE + +L + G
Sbjct: 420 YIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGG 466
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 51.2 bits (121), Expect = 2e-06
Identities = 49/219 (22%), Positives = 98/219 (44%), Gaps = 15/219 (6%)
Query: 198 DMERRDVDFEL---IKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCP 254
D++ +D D ++ + ++ GG+ D+ ++ G + K+ +H +M +++ KI +L C
Sbjct: 651 DVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMSSCIKNPKILLLKCS 710
Query: 255 FEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLL 314
E + + T ++ + E+E + +Q+I + L + + A +L
Sbjct: 711 IE---YLYREETKFTCID---PIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDML 764
Query: 315 LQNNLPAVRWVGGPEIELIAIATGGRIVPRFSE-LTAEKLG----FAGLVQEISFGTTKD 369
L++ + V V +E I+ T G +V + LT LG F + ++ TK
Sbjct: 765 LEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTK- 823
Query: 370 KMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCV 408
++ E C TI +RGG+ + K L +CV
Sbjct: 824 TLMFFEGCPQHLGCTIKLRGGSDYELARVKEILIFMICV 862
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 35.0 bits (79), Expect = 0.17
Identities = 46/216 (21%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 81 MDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQA 140
+D H+I L QD E A +E E L + + I+ + +A
Sbjct: 622 LDYQHEIENLQ----NQQDSE-----------RAAHAKEMEALRAKLMKVIKEKENSLEA 666
Query: 141 ARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGS-KVVNSCHRQMAEIAVNAVLTVADM 199
R LDK D LV+++DT +Q A+ + +V+ + + ++ N +
Sbjct: 667 IR---SKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKAT 723
Query: 200 ERRDVDFELIKVEGKVGGRLEDTKLIKGV-IVDKDFSHPQMPKKVEDAKIAILTCPFEPP 258
E + +D + ++ + G+ E KL + + +K H ++ K E +K + +T
Sbjct: 724 EEKLLDLDALR-KASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSIT------ 776
Query: 259 KPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKE 294
+ +L +T++++ + KE E+ +Q +KE
Sbjct: 777 RELQGRELKLTNLQENLSEVSQVKETLEKELQILKE 812
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 35.0 bits (79), Expect = 0.17
Identities = 46/216 (21%), Positives = 93/216 (43%), Gaps = 27/216 (12%)
Query: 81 MDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQA 140
+D H+I L QD E A +E E L + + I+ + +A
Sbjct: 657 LDYQHEIENLQ----NQQDSE-----------RAAHAKEMEALRAKLMKVIKEKENSLEA 701
Query: 141 ARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGS-KVVNSCHRQMAEIAVNAVLTVADM 199
R LDK D LV+++DT +Q A+ + +V+ + + ++ N +
Sbjct: 702 IR---SKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKAT 758
Query: 200 ERRDVDFELIKVEGKVGGRLEDTKLIKGV-IVDKDFSHPQMPKKVEDAKIAILTCPFEPP 258
E + +D + ++ + G+ E KL + + +K H ++ K E +K + +T
Sbjct: 759 EEKLLDLDALR-KASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSIT------ 811
Query: 259 KPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKE 294
+ +L +T++++ + KE E+ +Q +KE
Sbjct: 812 RELQGRELKLTNLQENLSEVSQVKETLEKELQILKE 847
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 34.7 bits (78), Expect = 0.23
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 16/100 (16%)
Query: 160 KDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRL 219
KD PL QT + S NS +LT+ D R DV ++K+ G +
Sbjct: 22183 KDNVPLKQTTRVNAESTENNS------------LLTIKDACREDVGHYVVKLTNSAGEAI 22230
Query: 220 EDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPK 259
E +I ++DK P P K+++ +T + PPK
Sbjct: 22231 ETLNVI---VLDKP-GPPTGPVKMDEVTADSITLSWGPPK 22266
Score = 30.8 bits (68), Expect = 3.3
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 176 KVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFS 235
+VV S H + + +++L + D+ R+D + + E G DT+ IK V++D
Sbjct: 18938 EVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSG---TDTQKIKVVVMDAP-G 18993
Query: 236 HPQMPKKVED 245
PQ P + D
Sbjct: 18994 PPQPPFDISD 19003
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 34.7 bits (78), Expect = 0.23
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 16/100 (16%)
Query: 160 KDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRL 219
KD PL QT + S NS +LT+ D R DV ++K+ G +
Sbjct: 15878 KDNVPLKQTTRVNAESTENNS------------LLTIKDACREDVGHYVVKLTNSAGEAI 15925
Query: 220 EDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPK 259
E +I ++DK P P K+++ +T + PPK
Sbjct: 15926 ETLNVI---VLDKP-GPPTGPVKMDEVTADSITLSWGPPK 15961
Score = 30.8 bits (68), Expect = 3.3
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 176 KVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFS 235
+VV S H + + +++L + D+ R+D + + E G DT+ IK V++D
Sbjct: 12633 EVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSG---TDTQKIKVVVMDAP-G 12688
Query: 236 HPQMPKKVED 245
PQ P + D
Sbjct: 12689 PPQPPFDISD 12698
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 34.7 bits (78), Expect = 0.23
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 16/100 (16%)
Query: 160 KDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRL 219
KD PL QT + S NS +LT+ D R DV ++K+ G +
Sbjct: 15811 KDNVPLKQTTRVNAESTENNS------------LLTIKDACREDVGHYVVKLTNSAGEAI 15858
Query: 220 EDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPK 259
E +I ++DK P P K+++ +T + PPK
Sbjct: 15859 ETLNVI---VLDKP-GPPTGPVKMDEVTADSITLSWGPPK 15894
Score = 30.8 bits (68), Expect = 3.3
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 176 KVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFS 235
+VV S H + + +++L + D+ R+D + + E G DT+ IK V++D
Sbjct: 12566 EVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSG---TDTQKIKVVVMDAP-G 12621
Query: 236 HPQMPKKVED 245
PQ P + D
Sbjct: 12622 PPQPPFDISD 12631
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 34.7 bits (78), Expect = 0.23
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 16/100 (16%)
Query: 160 KDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRL 219
KD PL QT + S NS +LT+ D R DV ++K+ G +
Sbjct: 15686 KDNVPLKQTTRVNAESTENNS------------LLTIKDACREDVGHYVVKLTNSAGEAI 15733
Query: 220 EDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPK 259
E +I ++DK P P K+++ +T + PPK
Sbjct: 15734 ETLNVI---VLDKP-GPPTGPVKMDEVTADSITLSWGPPK 15769
Score = 30.8 bits (68), Expect = 3.3
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 176 KVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFS 235
+VV S H + + +++L + D+ R+D + + E G DT+ IK V++D
Sbjct: 12441 EVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSG---TDTQKIKVVVMDAP-G 12496
Query: 236 HPQMPKKVED 245
PQ P + D
Sbjct: 12497 PPQPPFDISD 12506
>gi|197313636 N-methyl-D-aspartate receptor subunit 2A isoform 1
precursor [Homo sapiens]
Length = 1464
Score = 30.0 bits (66), Expect = 5.6
Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 4/55 (7%)
Query: 219 LEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVED 273
LED+K K ++ D +P + +D ++ I CP +P KH L +V D
Sbjct: 1348 LEDSKRSKSLLPDHTSDNPFLHSHRDDQRLVIGRCPSDP----YKHSLPSQAVND 1398
>gi|4504125 N-methyl-D-aspartate receptor subunit 2A isoform 1
precursor [Homo sapiens]
Length = 1464
Score = 30.0 bits (66), Expect = 5.6
Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 4/55 (7%)
Query: 219 LEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVED 273
LED+K K ++ D +P + +D ++ I CP +P KH L +V D
Sbjct: 1348 LEDSKRSKSLLPDHTSDNPFLHSHRDDQRLVIGRCPSDP----YKHSLPSQAVND 1398
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 30.0 bits (66), Expect = 5.6
Identities = 29/119 (24%), Positives = 50/119 (42%), Gaps = 19/119 (15%)
Query: 82 DVDHQIAKLMVELSKSQDDEIGDGT-----TGVVVLAGALLEEAEQ------LLDRGIHP 130
D + ++VE+ K + D T V+VL + + ++ LL G+H
Sbjct: 1199 DNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIKVQTKEGGYFHVLLAPGVHN 1258
Query: 131 I-RIADGYEQAARVAIEHLDKISDSVLVDIKDT-------EPLIQTAKTTLGSKVVNSC 181
I IADGY+Q H D S V+V D E ++ + T+ + ++ +C
Sbjct: 1259 IIAIADGYQQQHSQVFVHHDAASSVVIVFDTDNRIFGLPRELVVTVSGATMSALILTAC 1317
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,030,897
Number of Sequences: 37866
Number of extensions: 731239
Number of successful extensions: 2197
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2085
Number of HSP's gapped (non-prelim): 72
length of query: 541
length of database: 18,247,518
effective HSP length: 107
effective length of query: 434
effective length of database: 14,195,856
effective search space: 6161001504
effective search space used: 6161001504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.