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Search of human proteins with 24307879
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo
sapiens]
(638 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo sa... 1301 0.0
gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a... 1009 0.0
gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform... 1007 0.0
gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform... 965 0.0
gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens] 129 6e-30
gi|6912338 dynein, axonemal, intermediate chain 1 [Homo sapiens] 108 2e-23
gi|66267730 WD repeat domain 34 [Homo sapiens] 104 3e-22
gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo ... 103 4e-22
gi|155030242 WD repeat domain 60 [Homo sapiens] 64 6e-10
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 56 1e-07
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 56 1e-07
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 56 1e-07
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 56 1e-07
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 55 2e-07
gi|217272887 WD repeat domain 63 [Homo sapiens] 55 2e-07
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 54 6e-07
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 52 2e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 51 3e-06
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 49 1e-05
gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens] 49 1e-05
gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] 49 1e-05
gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens] 49 1e-05
gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens] 49 1e-05
gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens] 49 1e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 47 5e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 47 5e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 5e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 5e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 5e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 5e-05
>gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo
sapiens]
Length = 638
Score = 1301 bits (3366), Expect = 0.0
Identities = 638/638 (100%), Positives = 638/638 (100%)
Query: 1 MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREA 60
MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREA
Sbjct: 1 MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREA 60
Query: 61 EALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDP 120
EALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDP
Sbjct: 61 EALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDP 120
Query: 121 SVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVA 180
SVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVA
Sbjct: 121 SVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVA 180
Query: 181 PKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQ 240
PKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQ
Sbjct: 181 PKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQ 240
Query: 241 INIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYN 300
INIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYN
Sbjct: 241 INIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYN 300
Query: 301 NNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLW 360
NNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLW
Sbjct: 301 NNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLW 360
Query: 361 DNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQD 420
DNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQD
Sbjct: 361 DNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQD 420
Query: 421 SMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPIT 480
SMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPIT
Sbjct: 421 SMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPIT 480
Query: 481 GIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALF 540
GIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALF
Sbjct: 481 GIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALF 540
Query: 541 ACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVG 600
ACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVG
Sbjct: 541 ACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVG 600
Query: 601 EQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA 638
EQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA
Sbjct: 601 EQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA 638
>gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a
[Homo sapiens]
Length = 645
Score = 1009 bits (2609), Expect = 0.0
Identities = 492/651 (75%), Positives = 561/651 (86%), Gaps = 19/651 (2%)
Query: 1 MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETD--QKKEAVAPVQEESDLEKKRR 58
MSDKS+LKAELERKKQRLAQIREEKKRKEEERKKKE D QKKE PVQ++SDL++KRR
Sbjct: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKE---PVQDDSDLDRKRR 57
Query: 59 EAEALLQSMGLTPESPIV-----------FSEYWVPPPMSPSSKSVSTPSEAGSQDSGDG 107
E EALLQS+G++PE P+V + Y VP PMSPSSKSVSTPSEAGSQDSGD
Sbjct: 58 ETEALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDL 117
Query: 108 AVGSRTLHWDTDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQ 167
+RTL WDTDPSVLQL SDS+LGR KLG++K+TQVDF PRE+V+Y+KETQTP+
Sbjct: 118 GPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATH 177
Query: 168 PKEDEEEDDDVVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFD 227
E++EED+++V K + E E KK E + APP ELTEEEKQQILHSEEFL FFD
Sbjct: 178 QSEEDEEDEEMVESKVGQDSELENQDKKQEVKE--APPRELTEEEKQQILHSEEFLIFFD 235
Query: 228 HSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDW 287
+ R++ERAL+E +IFFDYSGR+LE+K+G++QAGA LS NRQF+DE WSKHRVV+C+DW
Sbjct: 236 RTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDW 295
Query: 288 SSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNL 347
S QYPEL+VASYNNNEDAPHEPDGVALVWNMK+KKTTPEYVFHCQS+VMS FA+FHPNL
Sbjct: 296 SLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNL 355
Query: 348 VVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKI 407
VVGGTYSGQIVLWDNRS++RTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLI++STDGK+
Sbjct: 356 VVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKM 415
Query: 408 CSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAG 467
CSWSLDMLS PQ+SMELV+ +SK VAVT M+FP GDVNNFVVGSEEG+VYTACRHGSKAG
Sbjct: 416 CSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAG 475
Query: 468 ISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYV 527
I E+FEGHQGP+TGI+CH AVG +DFSHLFVTSSFDWTVKLWTTK+NKPLYSFEDNADYV
Sbjct: 476 IGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYV 535
Query: 528 YDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAV 587
YDVMWSP HPALFACVDGMGRLDLWNLNNDTEVPTAS+++EG ALNRVRW +G+E+AV
Sbjct: 536 YDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAV 595
Query: 588 GDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA 638
GDSEG+I +YDVGE +AVP NDEW RF RTL EI ANRAD+EEE + A
Sbjct: 596 GDSEGRIWVYDVGE-LAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 645
>gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform b
[Homo sapiens]
Length = 628
Score = 1007 bits (2604), Expect = 0.0
Identities = 490/640 (76%), Positives = 558/640 (87%), Gaps = 14/640 (2%)
Query: 1 MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETD--QKKEAVAPVQEESDLEKKRR 58
MSDKS+LKAELERKKQRLAQIREEKKRKEEERKKKE D QKKE PVQ++SDL++KRR
Sbjct: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKE---PVQDDSDLDRKRR 57
Query: 59 EAEALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDT 118
E EALLQS+G++PE P+V P PMSPSSKSVSTPSEAGSQDSGD +RTL WDT
Sbjct: 58 ETEALLQSIGISPEPPLV------PTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDT 111
Query: 119 DPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDV 178
DPSVLQL SDS+LGR KLG++K+TQVDF PRE+V+Y+KETQTP+ E++EED+++
Sbjct: 112 DPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEM 171
Query: 179 VAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALS 238
V K + E E KK E + APP ELTEEEKQQILHSEEFL FFD + R++ERAL+
Sbjct: 172 VESKVGQDSELENQDKKQEVKE--APPRELTEEEKQQILHSEEFLIFFDRTIRVIERALA 229
Query: 239 EQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVAS 298
E +IFFDYSGR+LE+K+G++QAGA LS NRQF+DE WSKHRVV+C+DWS QYPEL+VAS
Sbjct: 230 EDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVAS 289
Query: 299 YNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIV 358
YNNNEDAPHEPDGVALVWNMK+KKTTPEYVFHCQS+VMS FA+FHPNLVVGGTYSGQIV
Sbjct: 290 YNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIV 349
Query: 359 LWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHP 418
LWDNRS++RTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLI++STDGK+CSWSLDMLS P
Sbjct: 350 LWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTP 409
Query: 419 QDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGP 478
Q+SMELV+ +SK VAVT M+FP GDVNNFVVGSEEG+VYTACRHGSKAGI E+FEGHQGP
Sbjct: 410 QESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGP 469
Query: 479 ITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPA 538
+TGI+CH AVG +DFSHLFVTSSFDWTVKLWTTK+NKPLYSFEDNADYVYDVMWSP HPA
Sbjct: 470 VTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPA 529
Query: 539 LFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYD 598
LFACVDGMGRLDLWNLNNDTEVPTAS+++EG ALNRVRW +G+E+AVGDSEG+I +YD
Sbjct: 530 LFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYD 589
Query: 599 VGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA 638
VGE +AVP NDEW RF RTL EI ANRAD+EEE + A
Sbjct: 590 VGE-LAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 628
>gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform c
[Homo sapiens]
Length = 608
Score = 965 bits (2495), Expect = 0.0
Identities = 475/641 (74%), Positives = 542/641 (84%), Gaps = 36/641 (5%)
Query: 1 MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETD--QKKEAVAPVQEESDLEKKRR 58
MSDKS+LKAELERKKQRLAQIREEKKRKEEERKKKE D QKKE PVQ++SDL++KRR
Sbjct: 1 MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKE---PVQDDSDLDRKRR 57
Query: 59 EAEALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGD-GAVGSRTLHWD 117
E EALLQS+G++PE P+V P PMSPSSKSVSTPSEAGSQDSGD G + R LH
Sbjct: 58 ETEALLQSIGISPEPPLV------PTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLH-- 109
Query: 118 TDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDD 177
KLG++K+TQVDF PRE+V+Y+KETQTP+ E++EED++
Sbjct: 110 -------------------KLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEE 150
Query: 178 VVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERAL 237
+V K + E E KK E + APP ELTEEEKQQILHSEEFL FFD + R++ERAL
Sbjct: 151 MVESKVGQDSELENQDKKQEVKE--APPRELTEEEKQQILHSEEFLIFFDRTIRVIERAL 208
Query: 238 SEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVA 297
+E +IFFDYSGR+LE+K+G++QAGA LS NRQF+DE WSKHRVV+C+DWS QYPEL+VA
Sbjct: 209 AEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVA 268
Query: 298 SYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQI 357
SYNNNEDAPHEPDGVALVWNMK+KKTTPEYVFHCQS+VMS FA+FHPNLVVGGTYSGQI
Sbjct: 269 SYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQI 328
Query: 358 VLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSH 417
VLWDNRS++RTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLI++STDGK+CSWSLDMLS
Sbjct: 329 VLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLST 388
Query: 418 PQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQG 477
PQ+SMELV+ +SK VAVT M+FP GDVNNFVVGSEEG+VYTACRHGSKAGI E+FEGHQG
Sbjct: 389 PQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQG 448
Query: 478 PITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHP 537
P+TGI+CH AVG +DFSHLFVTSSFDWTVKLWTTK+NKPLYSFEDNADYVYDVMWSP HP
Sbjct: 449 PVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHP 508
Query: 538 ALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIY 597
ALFACVDGMGRLDLWNLNNDTEVPTAS+++EG ALNRVRW +G+E+AVGDSEG+I +Y
Sbjct: 509 ALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVY 568
Query: 598 DVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA 638
DVGE +AVP NDEW RF RTL EI ANRAD+EEE + A
Sbjct: 569 DVGE-LAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA 608
>gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens]
Length = 848
Score = 129 bits (325), Expect = 6e-30
Identities = 122/480 (25%), Positives = 196/480 (40%), Gaps = 64/480 (13%)
Query: 174 EDDDVVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIV 233
+D D P E E + D EN A HE E+ IL S++F R++
Sbjct: 352 KDQDQRLPGSTTEKNSETSSLMDIENVILAKIHEDEEDHSDAILKSDKFHQDLFFMERVL 411
Query: 234 -------ERALSEQINIFFDYSGRDLED---------------KEGEIQAGAKLSLNRQF 271
+ A Q+ + + + ED KE E + A+ S
Sbjct: 412 MENIFQPKLAAYRQLPVLKEPEPEEPEDVLESAKHEEVEEESKKEEEEEIHAEESTIPAN 471
Query: 272 FDERWS------KHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTP 325
+ WS K VS L W+ P+LL Y + + G+A W++K P
Sbjct: 472 LERLWSFSCDLTKGLNVSSLAWNKTNPDLLAVGYGHF-GFKEQKRGLACCWSIK-NPMWP 529
Query: 326 EYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVY 385
E ++ V + F+ PNL+ G ++G I +++ RSN PV + S H PV+
Sbjct: 530 ERIYQSPYGVTAVDFSIGAPNLLAVGYHNGTIAIYNVRSNSNVPVLDSSESPQKHLGPVW 589
Query: 386 CVNVV-------GTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVH-----------K 427
+ + G L+SIS DG+I W + D M L K
Sbjct: 590 QLQWIEQDRGTTGDGKREILVSISADGRISKWVIRKGLDCYDLMRLKRTTAASNKKGGEK 649
Query: 428 QSKAVAVTS-------MSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPIT 480
+ K A+ S +F D N ++ G+EEG ++ C + + GH+GP+
Sbjct: 650 EKKDEALISRQAPGMCFAFHPKDTNIYLAGTEEGHIHK-CSCSYNEQYLDTYRGHKGPVY 708
Query: 481 GIHCHAAVGAVDFSH-LFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPAL 539
+ + F H +F++ S DW V +W +N KP SF VYDV WSP +
Sbjct: 709 KVTWNP------FCHDVFLSCSADWGVIIWQQENVKPSLSFYPATSVVYDVAWSPKSSYI 762
Query: 540 FACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDV 599
FA + R+++W+L+ T P + + + + VGDS+GQ+ +Y++
Sbjct: 763 FAAAN-ENRVEIWDLHISTLDPLIVNTANPGIKFTTILFAKQTDCLLVGDSDGQVSVYEL 821
>gi|6912338 dynein, axonemal, intermediate chain 1 [Homo sapiens]
Length = 699
Score = 108 bits (270), Expect = 2e-23
Identities = 110/430 (25%), Positives = 187/430 (43%), Gaps = 34/430 (7%)
Query: 188 EEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEF----LSFFDHSTRIVERALSEQI-- 241
E EK K E+ +K P + + + + L S E L + +I+ER +++
Sbjct: 237 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD 296
Query: 242 NIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNN 301
+I D+ D E Q G L L + F +K V+ L W+ +Y +L Y +
Sbjct: 297 DIAQDFKYYDDAADEYRDQVGTLLPLWK--FQNDKAKRLSVTALCWNPKYRDLFAVGYGS 354
Query: 302 NEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWD 361
D + G+ L++++K + PEY+F S VM HP LV G Y G + +++
Sbjct: 355 Y-DFMKQSRGMLLLYSLK-NPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYN 412
Query: 362 NRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNL--ISISTDGKICSWSL--DMLSH 417
+ P + + H+ PV+ V NL S+S+DG+I SW+L L H
Sbjct: 413 LKKPHSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVH 472
Query: 418 PQDSMELVHKQSKAVAVTSMSFPVG-----DVNN-----FVVGSEEGSVYTACRHGSKAG 467
V + V PVG D + F+VG+EEG +Y C +
Sbjct: 473 IDVIKLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIY-KCSKSYSSQ 531
Query: 468 ISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYV 527
+ ++ H + + + + +F++ S DWTVK+W P++ ++ N+ V
Sbjct: 532 FLDTYDAHNMSVDTVSWNPY-----HTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNS-AV 585
Query: 528 YDVMWSPTHPALFACVDGMGRLDLWNL--NNDTEVPTASISVEGNPALNRVRWTHSGREI 585
DV W+P +FA V G+ +++L N + ++ + N L V++ I
Sbjct: 586 GDVAWAPYSSTVFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKN-RLTHVQFNLIHPII 644
Query: 586 AVGDSEGQIV 595
VGD G I+
Sbjct: 645 IVGDDRGHII 654
>gi|66267730 WD repeat domain 34 [Homo sapiens]
Length = 536
Score = 104 bits (259), Expect = 3e-22
Identities = 80/323 (24%), Positives = 143/323 (44%), Gaps = 41/323 (12%)
Query: 316 WNMKYKKTTPEY---VFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQR 372
WN+ + P+ V SAV+ F P+ V GG YSG++++WD + + R
Sbjct: 198 WNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWR 257
Query: 373 TPLSAAAHTHPVYCVNVV---GTQNAHNLISISTDGKICSW--------------SLDML 415
T L+ HT PV V + G + ++S++TDGK+ W +L M
Sbjct: 258 TGLTDDTHTDPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQ 317
Query: 416 SHPQDSMELVHKQSKA-VAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEM--- 471
P+ + H + + V T+++F D F++G+E G +A ++ M
Sbjct: 318 QLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEGGFPLKCSLAAGEAALTRMPSS 377
Query: 472 ----------FEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFE 521
F H GPI + C +LF+++ D V L++ PL S +
Sbjct: 378 VPLRAPAQFTFSPHGGPIYSVSCSPF-----HRNLFLSAGTDGHVHLYSMLQAPPLTSLQ 432
Query: 522 DNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASI--SVEGNPALNRVRWT 579
+ Y++ V WSP P +FA G G + L++L ++ PT I + + +P +
Sbjct: 433 LSLKYLFAVRWSPVRPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQDESPVYCLEFNS 492
Query: 580 HSGREIAVGDSEGQIVIYDVGEQ 602
+ +A GD++G + ++ + +
Sbjct: 493 QQTQLLAAGDAQGTVKVWQLSTE 515
>gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo
sapiens]
Length = 605
Score = 103 bits (258), Expect = 4e-22
Identities = 97/416 (23%), Positives = 183/416 (43%), Gaps = 26/416 (6%)
Query: 207 ELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQ--INIFFDYSGRDLEDKEGEIQAGAK 264
E T ++++ E +++ I+E + + I+I+ +Y + + E AK
Sbjct: 91 EQTIRFRKKVEKDENYVNAIMQLGSIMEHCIKQNNAIDIYEEYFNDEEAMEVMEEDPSAK 150
Query: 265 LSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYN--NNEDAPHEPDGVALVWNMKYKK 322
++N F + R + L W L +Y+ + + AP + +W+++
Sbjct: 151 -TIN--VFRDPQEIKRAATHLSWHPDGNRKLAVAYSCLDFQRAPVGMSSDSYIWDLE-NP 206
Query: 323 TTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTH 382
PE S +++ F ++++GG Y+GQI WD R K + V ++H
Sbjct: 207 NKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTR--KGSLVAELSTIESSHRD 264
Query: 383 PVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDS--MELVHKQS--KAVAVTSMS 438
PVY + ++ S STDG++ W + +S P + +++ K+ A+ S+
Sbjct: 265 PVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVILDITKKEQLENALGAISLE 324
Query: 439 FPVGDVNNFVVGSEEGSVYTACRHGSKAGISEM---FEGHQGPITGIHCHAAVGAVDFSH 495
F F+VG+E+G V + C +K ++ F GH GPI + + +
Sbjct: 325 FESTLPTKFMVGTEQGIVIS-CNRKAKTSAEKIVCTFPGHHGPIYALQRNPF-----YPK 378
Query: 496 LFVTSSFDWTVKLWTTKNNKPLYSFED-NADYVYDVMWSPTHPALFACVDGMGRLDLWNL 554
F+T DWT ++W+ + + + + Y+ D WSP P +F G LD+W+
Sbjct: 379 NFLTVG-DWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWDF 437
Query: 555 NNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDE 610
+ PT S+ V + AL +R +G IA G G + +V ++ + +E
Sbjct: 438 MFEQCDPTLSLKV-CDEALFCLRVQDNGCLIACGSQLGTTTLLEVSPGLSTLQRNE 492
>gi|155030242 WD repeat domain 60 [Homo sapiens]
Length = 1066
Score = 63.5 bits (153), Expect = 6e-10
Identities = 81/386 (20%), Positives = 145/386 (37%), Gaps = 83/386 (21%)
Query: 312 VALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRS------- 364
V VW++ ++ + P+ V C+S V + L+ GT G +V+WD R
Sbjct: 677 VLCVWDI-WQPSGPQKVLICESQVTCCCLSPLKAFLLFAGTAHGSVVVWDLREDSRLHYS 735
Query: 365 ------------------------NKRTPVQRT-PLSAAAHTHPVYCVNVVGTQN----- 394
N R+P+Q P+S + H + ++ TQ
Sbjct: 736 VTLSDGFWTFRTATFSTDGILTSVNHRSPLQAVEPISTSVHKKQSFVLSPFSTQEEMSGL 795
Query: 395 AHNLISISTDGKICSWSL-------------DMLSHPQDSMELVH------------KQS 429
+ ++ S+ G + W + D+ P ++LVH K +
Sbjct: 796 SFHIASLDESGVLNVWVVVELPKADIAGSISDLGLMPGGRVKLVHSALIQLGDSLSHKGN 855
Query: 430 KAVAVT---SMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHA 486
+ T ++ F D N+F++G++ G + R + ++F+ Q I +
Sbjct: 856 EFWGTTQTLNVKFLPSDPNHFIIGTDMGLISHGTRQDLRVA-PKLFKPQQHGIRPVK--- 911
Query: 487 AVGAVDFSH----LFVTSSFDWTVKLWTTKNNKPLYSFEDNADY--VYDVMWSPTHPALF 540
V +DFS +F+ D +++L + PL ++ + D V + WSPT PA+F
Sbjct: 912 -VNVIDFSPFGEPIFLAGCSDGSIRLHQLSSAFPLLQWDSSTDSHAVTGLQWSPTRPAVF 970
Query: 541 ACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRV------RWTHSGREIAVGDSEGQI 594
D + +W+L P A V N + + S + + + G I
Sbjct: 971 LVQDDTSNIYIWDLLQSDLGPVAKQQVSPNRLVAMAAVGEPEKAGGSFLALVLARASGSI 1030
Query: 595 VIYDVGEQIAVPRNDEWARFGRTLAE 620
I + + A P DE R L E
Sbjct: 1031 DIQHLKRRWAAPEVDECNRLRLLLQE 1056
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 55.8 bits (133), Expect = 1e-07
Identities = 76/330 (23%), Positives = 131/330 (39%), Gaps = 36/330 (10%)
Query: 276 WSKHRVVSCLDWSSQYPELLVASYN-NNEDAPHEPD------GVALVWNMKYKKTTPEYV 328
+S HR+V S + L++AS N+DA + G + K E
Sbjct: 26 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK 85
Query: 329 FHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQ----RTPLSAAAHTHPV 384
+ + V A + +P ++ T S ++++D + P L H
Sbjct: 86 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 145
Query: 385 YCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAV----TSMSFP 440
Y ++ + H L+S S D IC W + V K+ K V T +
Sbjct: 146 YGLSWNPNLSGH-LLSASDDHTICLWDISA----------VPKEGKVVDAKTIFTGHTAV 194
Query: 441 VGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQG-PITGIHCHAA-VGAVDFS---- 494
V DV+ ++ S++ + K I + + P + H A V + F+
Sbjct: 195 VEDVSWHLLHE---SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSE 251
Query: 495 HLFVTSSFDWTVKLWTTKNNK-PLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWN 553
+ T S D TV LW +N K L+SFE + D ++ V WSP + + A RL++W+
Sbjct: 252 FILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWD 311
Query: 554 LNNDTEVPTASISVEGNPALNRVRWTHSGR 583
L+ E + + +G P L + H+ +
Sbjct: 312 LSKIGEEQSPEDAEDGPPELLFIHGGHTAK 341
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 55.8 bits (133), Expect = 1e-07
Identities = 76/330 (23%), Positives = 131/330 (39%), Gaps = 36/330 (10%)
Query: 276 WSKHRVVSCLDWSSQYPELLVASYN-NNEDAPHEPD------GVALVWNMKYKKTTPEYV 328
+S HR+V S + L++AS N+DA + G + K E
Sbjct: 60 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK 119
Query: 329 FHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQ----RTPLSAAAHTHPV 384
+ + V A + +P ++ T S ++++D + P L H
Sbjct: 120 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 179
Query: 385 YCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAV----TSMSFP 440
Y ++ + H L+S S D IC W + V K+ K V T +
Sbjct: 180 YGLSWNPNLSGH-LLSASDDHTICLWDISA----------VPKEGKVVDAKTIFTGHTAV 228
Query: 441 VGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQG-PITGIHCHAA-VGAVDFS---- 494
V DV+ ++ S++ + K I + + P + H A V + F+
Sbjct: 229 VEDVSWHLLHE---SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSE 285
Query: 495 HLFVTSSFDWTVKLWTTKNNK-PLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWN 553
+ T S D TV LW +N K L+SFE + D ++ V WSP + + A RL++W+
Sbjct: 286 FILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWD 345
Query: 554 LNNDTEVPTASISVEGNPALNRVRWTHSGR 583
L+ E + + +G P L + H+ +
Sbjct: 346 LSKIGEEQSPEDAEDGPPELLFIHGGHTAK 375
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 55.8 bits (133), Expect = 1e-07
Identities = 76/330 (23%), Positives = 131/330 (39%), Gaps = 36/330 (10%)
Query: 276 WSKHRVVSCLDWSSQYPELLVASYN-NNEDAPHEPD------GVALVWNMKYKKTTPEYV 328
+S HR+V S + L++AS N+DA + G + K E
Sbjct: 61 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK 120
Query: 329 FHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQ----RTPLSAAAHTHPV 384
+ + V A + +P ++ T S ++++D + P L H
Sbjct: 121 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 180
Query: 385 YCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAV----TSMSFP 440
Y ++ + H L+S S D IC W + V K+ K V T +
Sbjct: 181 YGLSWNPNLSGH-LLSASDDHTICLWDISA----------VPKEGKVVDAKTIFTGHTAV 229
Query: 441 VGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQG-PITGIHCHAA-VGAVDFS---- 494
V DV+ ++ S++ + K I + + P + H A V + F+
Sbjct: 230 VEDVSWHLLHE---SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSE 286
Query: 495 HLFVTSSFDWTVKLWTTKNNK-PLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWN 553
+ T S D TV LW +N K L+SFE + D ++ V WSP + + A RL++W+
Sbjct: 287 FILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWD 346
Query: 554 LNNDTEVPTASISVEGNPALNRVRWTHSGR 583
L+ E + + +G P L + H+ +
Sbjct: 347 LSKIGEEQSPEDAEDGPPELLFIHGGHTAK 376
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 55.8 bits (133), Expect = 1e-07
Identities = 60/265 (22%), Positives = 114/265 (43%), Gaps = 25/265 (9%)
Query: 332 QSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQ----RTPLSAAAHTHPVYCV 387
+ V A + +P+++ T S ++++D + P L H Y +
Sbjct: 123 EGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGL 182
Query: 388 NVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNF 447
+ + H L+S S D +C W D+ + P++ + +KA+ T S V DV
Sbjct: 183 SWNSNLSGH-LLSASDDHTVCLW--DINAGPKEGKIV---DAKAI-FTGHSAVVEDVAWH 235
Query: 448 V--------VGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVT 499
+ V ++ + R + + S + + H + +C + +F + T
Sbjct: 236 LLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEV---NCLSFNPYSEF--ILAT 290
Query: 500 SSFDWTVKLWTTKNNK-PLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDT 558
S D TV LW +N K L++FE + D ++ V WSP + + A RL++W+L+
Sbjct: 291 GSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIG 350
Query: 559 EVPTASISVEGNPALNRVRWTHSGR 583
E +A + +G P L + H+ +
Sbjct: 351 EEQSAEDAEDGPPELLFIHGGHTAK 375
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 55.5 bits (132), Expect = 2e-07
Identities = 52/253 (20%), Positives = 105/253 (41%), Gaps = 26/253 (10%)
Query: 8 KAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSM 67
K LE + + L ++EE ++ E E K++ +E +A + + + E + L M
Sbjct: 166 KKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDM 225
Query: 68 GLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDPSVLQLHS 127
+ + +E P + + +EA + SGD + + + ++ +
Sbjct: 226 ----DGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYR 281
Query: 128 DSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPIEP 187
L T + P +T KE Q PV + P E+EEE++ E
Sbjct: 282 SEALP-----------TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEE---------EE 321
Query: 188 EEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDY 247
EEE+ +++EE DS+ P L+ + ++ + + + ++ A ++ F+
Sbjct: 322 EEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAA--QEARNKFEE 379
Query: 248 SGRDLEDKEGEIQ 260
+ R L+D E I+
Sbjct: 380 AERSLKDMEESIR 392
>gi|217272887 WD repeat domain 63 [Homo sapiens]
Length = 891
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/171 (25%), Positives = 77/171 (45%), Gaps = 17/171 (9%)
Query: 205 PHELTEEEKQQILHSEEFLSFFDHSTRIVERAL--SEQINIFFDYSGRDLEDKEGEI--Q 260
P E +EEEK+ + S+ + F ++++ VE AL +E +N F D + L ++EG +
Sbjct: 259 PREFSEEEKETLKQSKPLVDFLNNASISVEIALQQNEIMNTFID-DWKYLAEEEGTFGDK 317
Query: 261 AGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYN---NNEDAPH-------EPD 310
L + F D ++++C+ W L+ S + ED H +P
Sbjct: 318 TDTHLKEYQSFTDLHSPTEKMITCVSWHPTIYGLIAVSVAVRLSFEDRVHFSGKLLLQPS 377
Query: 311 GVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWD 361
+ L W+ P+ + + F PN++ GG +GQIV+WD
Sbjct: 378 -LILFWSFS-DPIHPQLMLESPDDIFCFKFCPSDPNIIAGGCINGQIVMWD 426
Score = 36.2 bits (82), Expect = 0.095
Identities = 51/226 (22%), Positives = 84/226 (37%), Gaps = 15/226 (6%)
Query: 399 ISISTDGKICSWSLDMLSHPQ----DSMELVHKQSKAVAVTSMSFPVGDV-NNFVVGSEE 453
IS++ D +C ML+ + + M H +A ++ P+ D F VG+EE
Sbjct: 583 ISLNEDHLLCKTQDKMLAQSKTEKAEEMNPYHNLESGMA--NLLKPIDDFCTKFFVGTEE 640
Query: 454 GSV-YTACRHGSKAGISEMFEGHQGPITGIH---CHAAVGAVDFSHLFVTSSFDWTVKLW 509
G V YT + + IH H + ++ + +T W V +W
Sbjct: 641 GEVIYTDWKMEKDPETGRLMSKKPVSHHTIHDGTVHTIQRSPFYNDIILTVG-GWNVAIW 699
Query: 510 TTK-NNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVE 568
PL WS T P +F G +D+W+L T P S ++
Sbjct: 700 KEGVMTGPLLQSCCAPKRYTSGHWSLTRPGVFYIGREDGYIDIWDLLEKTHEPAQSQNIC 759
Query: 569 GNPALNRVRWTHSGRE--IAVGDSEGQIVIYDVGEQIAVPRNDEWA 612
W S ++ IA D G + I ++ ++ P +E A
Sbjct: 760 ITMITYIKPWIFSSKQQFIATADYYGTLHILEIPWTLSRPSTNEMA 805
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 53.5 bits (127), Expect = 6e-07
Identities = 57/253 (22%), Positives = 104/253 (41%), Gaps = 29/253 (11%)
Query: 8 KAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSM 67
K LE + + L ++EE ++ E E K++ +E +A + + + E + L M
Sbjct: 166 KKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDM 225
Query: 68 GLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDPSVLQLHS 127
+ + +E P + + +EA + SGD + + + ++ +
Sbjct: 226 ----DGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYR 281
Query: 128 DSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPIEP 187
L T + P +T KE Q PV + P E+EEE++ E
Sbjct: 282 SEALP-----------TDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEE---------EE 321
Query: 188 EEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDY 247
EEE+ +++EE DS+ E+ K E+ + +D T+ A E N F+
Sbjct: 322 EEEEAEEEEEEEDSEVQ----GEQPKPASPAEEDKMPPYDEQTQAFIDAAQEARN-KFEE 376
Query: 248 SGRDLEDKEGEIQ 260
+ R L+D E I+
Sbjct: 377 AERSLKDMEESIR 389
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 51.6 bits (122), Expect = 2e-06
Identities = 67/317 (21%), Positives = 123/317 (38%), Gaps = 61/317 (19%)
Query: 8 KAELERKKQRLAQIREEKKRKEEERKKKETDQKK------------------EAVAPVQE 49
K + RK R+ E++R++EER ++E K E V ++
Sbjct: 158 KRGVARKVVRMVIRHHEEQRQKEERARREEQAKLRRIASTMAKDVRQFWSNVEKVVQFKQ 217
Query: 50 ESDLEKKRREA------------EALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPS 97
+S LE+KR++A E + + P+ S+ P + SS + S P
Sbjct: 218 QSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQSLNQPLTSSKAGSSPCLGSSSAASSPPP 277
Query: 98 EAGSQDSGDGAVGSRTLHWDTDPSVLQLH-----SDSDLGRGPIKL----GMAKITQV-- 146
A D DG + + D +++ +D++ R I+L G + ++
Sbjct: 278 PASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLR 337
Query: 147 DFPPREIVTYTKETQTPVMAQ------PKED-EEEDDDVVAPKPP---IEPEEEKTLKKD 196
PP+ + + +QTP P+E EEE V+ KPP + ++ D
Sbjct: 338 SLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPD 397
Query: 197 EENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRI----------VERALSEQINIFFD 246
E+++ E E+E+ I E+ DH+ + +E L + +
Sbjct: 398 EDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYAP 457
Query: 247 YSGRDLEDKEGEIQAGA 263
SG ++ E E+ A +
Sbjct: 458 GSGSSEDEDEDEVDANS 474
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 51.2 bits (121), Expect = 3e-06
Identities = 50/224 (22%), Positives = 103/224 (45%), Gaps = 23/224 (10%)
Query: 4 KSELKAELERKKQRLAQIREEKKRKEEERK--KKETDQKKEAVAPVQEESDLEKKRR--- 58
KS +KAE + ++ + ++EE K E+ + K+E ++A +PV+EE+ +K +
Sbjct: 681 KSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPV 740
Query: 59 EAEALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDT 118
+ EA +PE + P +P+ + +P++ + +
Sbjct: 741 KEEAKSPEKAKSPEKAKTL-DVKSPEAKTPAKEEARSPADKFPEKAKS------------ 787
Query: 119 DPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIV-TYTKETQTPVMAQPKEDEEEDDD 177
V + + + P+K AK + + P +E V + KE + P + KE ++ ++
Sbjct: 788 --PVKEEVKSPEKAKSPLKED-AKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEE 844
Query: 178 VVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEE 221
AP P + EE+K KK+E +AP ++ E+++ + +E
Sbjct: 845 EKAPATP-KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE 887
Score = 48.5 bits (114), Expect = 2e-05
Identities = 50/220 (22%), Positives = 97/220 (44%), Gaps = 22/220 (10%)
Query: 4 KSELKAELERKKQRLAQIREEKKRKEEERK--KKETDQKKEAVAPVQEESDLEKKRREAE 61
KS +K E + ++ + ++EE K E+ + K+E ++A +PV+EE+ +K + E
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754
Query: 62 ALLQSMGLTPESPIVFSEYWVPPP-------MSPSSKSVSTPSEAGSQDSGDGAVGSRTL 114
+PE+ E P SP + V +P +A S D + +
Sbjct: 755 KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEI 814
Query: 115 HWDTDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEE 174
P ++ S P ++ +V PP++ K TP + K+ ++E
Sbjct: 815 -----PKKEEVKSPVKEEEKPQEV------KVKEPPKK-AEEEKAPATPKTEEKKDSKKE 862
Query: 175 D-DDVVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEK 213
+ APKP +E ++E ++K +E+ +A E +++K
Sbjct: 863 EAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902
Score = 47.8 bits (112), Expect = 3e-05
Identities = 55/235 (23%), Positives = 102/235 (43%), Gaps = 39/235 (16%)
Query: 4 KSELKAELERKKQRLAQIREEKKRKEEERK--KKETDQKKEAVAPVQEESDLEKKRREAE 61
KS +KAE + ++ + ++ E K E+ + K+E ++A +PV+EE+ K +A+
Sbjct: 667 KSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA---KSPEKAK 723
Query: 62 ALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTD-- 119
+ ++ TPE SP + +P +A S + ++TL +
Sbjct: 724 SPVKEEAKTPEKA-----------KSPVKEEAKSPEKAKSPEK------AKTLDVKSPEA 766
Query: 120 --PSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPK-------- 169
P+ + S +D + P K +V P + ++ + P PK
Sbjct: 767 KTPAKEEARSPAD--KFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824
Query: 170 EDEEEDDDVVAPKPPIEPEEEK---TLKKDEENDSKAPPHELTEEEKQQILHSEE 221
++EE+ +V +PP + EEEK T K +E+ DSK E K ++ +E
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKE 879
Score = 46.2 bits (108), Expect = 9e-05
Identities = 52/212 (24%), Positives = 83/212 (39%), Gaps = 44/212 (20%)
Query: 8 KAELERKKQRLAQIREEKKRKEEERKKKET-----DQKKEAVAPVQEESDLEKKRREAEA 62
KAE E K + E+K K+EE KKE ++KKE +ES +E K+ EAE
Sbjct: 841 KAE-EEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE- 898
Query: 63 LLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDPSV 122
+ VP P + V +A ++ + V
Sbjct: 899 ---------------DKKKVPTPEKEAPAKVEVKEDAKPKEKTE---------------V 928
Query: 123 LQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPK 182
+ D + P K K + P + T ++ + P E + ++DD K
Sbjct: 929 AKKEPDDAKAKEPSKPAEKK----EAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSK 984
Query: 183 PPIEPEEEKTLKKD--EENDSKAPPHELTEEE 212
P +P+ EK K ++ DSK PP + TE++
Sbjct: 985 EPSKPKAEKAEKSSSTDQKDSK-PPEKATEDK 1015
Score = 37.7 bits (86), Expect = 0.033
Identities = 52/229 (22%), Positives = 88/229 (38%), Gaps = 39/229 (17%)
Query: 4 KSELKAELERKKQRLAQI----------------REEKKRKEEERKKKETDQKKEAVA-- 45
KSE K ++ K ++ I EEK+ KEEE K++E +++EA
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGE 498
Query: 46 ------PVQEESDLEKKRR---EAEALLQSMGLTPESPIVFSEYWVPPP---MSPSSKSV 93
P +E + EK+ + + EA + +PE S V P SP+ +
Sbjct: 499 EETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 558
Query: 94 STPSEAGSQDSGDGAVGSRTLHWDTDPSVLQLHSDS-------DLGRGPIKLGMAKITQV 146
+P EA S + + + + S + + S + + P+K +
Sbjct: 559 KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEA 618
Query: 147 DFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPIEPEEEKTLKK 195
P +E E ++P A+ EE A P E EE K+ +K
Sbjct: 619 KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP--EKEEAKSPEK 665
Score = 37.7 bits (86), Expect = 0.033
Identities = 44/223 (19%), Positives = 81/223 (36%), Gaps = 32/223 (14%)
Query: 4 KSELKAELERKKQRLAQ--IREEKKR--------KEEERKKKETDQKKEAVAPVQEESDL 53
K E K+ E K A+ ++EE K KEE + E ++A +P +EE+
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648
Query: 54 EKKRREAEALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRT 113
+K + E +SP+ SP +P +A S
Sbjct: 649 PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKS------------ 696
Query: 114 LHWDTDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEE 173
V + + + P+K + P +E ++ ++PV + K E+
Sbjct: 697 -------PVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK 749
Query: 174 EDDDVVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQI 216
A ++ E KT K+E +++P + E+ K +
Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEE---ARSPADKFPEKAKSPV 789
Score = 36.2 bits (82), Expect = 0.095
Identities = 50/223 (22%), Positives = 94/223 (42%), Gaps = 24/223 (10%)
Query: 4 KSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEES---DLEKKRREA 60
KS +K E++ ++ + ++E+ K E+E KKE E +PV+EE +++ K
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE-----EVKSPVKEEEKPQEVKVKEPPK 840
Query: 61 EALLQSMGLTP--ESPIVFSEYWVPPPMSPSSK-------SVSTPSEAGSQDSGDGAVGS 111
+A + TP E + P +P K +V P E+ + + A
Sbjct: 841 KAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900
Query: 112 RTLHWDTDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKED 171
+ + + ++ D + K +AK D +E +K + A K+D
Sbjct: 901 KKVPTPEKEAPAKVEVKED-AKPKEKTEVAKKEPDDAKAKEP---SKPAEKKEAAPEKKD 956
Query: 172 EEEDDDVVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQ 214
+E+ A KP +P+ E K+D++ SK P E+ ++
Sbjct: 957 TKEEK---AKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEK 996
Score = 30.8 bits (68), Expect = 4.0
Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 7/70 (10%)
Query: 149 PPREIVTYTKETQTPVMAQPKEDEE----EDDDVVAPKPPIEPEEEKTLKKDEENDSKAP 204
P E + KE ++PV + K E E ++ +P PE+ K+ K+E +K+P
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE---AKSP 561
Query: 205 PHELTEEEKQ 214
P + E+++
Sbjct: 562 PEAKSPEKEE 571
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 477 GPITGIHCHAA-VGAVDFSH-----LFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDV 530
GP+ HA V +VD+S L V+ S+D TVKLW K L +F + +Y
Sbjct: 102 GPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYST 161
Query: 531 MWSPTHPALFACVDGMGRLDLWNL 554
+WSP P FA G L +W++
Sbjct: 162 IWSPHIPGCFASASGDQTLRIWDV 185
Score = 31.6 bits (70), Expect = 2.3
Identities = 45/175 (25%), Positives = 63/175 (36%), Gaps = 35/175 (20%)
Query: 448 VVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCH-AAVGAV-----DFSHLFVTSS 501
V G + T RHG A S G T H A G + D + L + S
Sbjct: 4 VCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRS 63
Query: 502 FDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVP 561
FDW D ++DV WS + + G G L LW DT
Sbjct: 64 FDWN-------------------DGLFDVTWSENNEHVLITCSGDGSLQLW----DTAKA 100
Query: 562 TASISV--EGNPALNRVRWTHS-GREIAVGDSEGQIV-IYD--VGEQIAVPRNDE 610
+ V E + V W+ + G ++ V S Q V ++D VG+ + R E
Sbjct: 101 AGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHE 155
Score = 31.2 bits (69), Expect = 3.1
Identities = 34/134 (25%), Positives = 54/134 (40%), Gaps = 18/134 (13%)
Query: 305 APHEP--------DGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQ 356
+PH P D +W++K H Q+ ++S + K++ NL+V G
Sbjct: 164 SPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAH-QAEILSCDWCKYNENLLVTGAVDCS 222
Query: 357 IVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLS 416
+ WD R N R PV HT+ + V +A L S S D + W+ S
Sbjct: 223 LRGWDLR-NVRQPV----FELLGHTYAIRRVK-FSPFHASVLASCSYDFTVRFWN---FS 273
Query: 417 HPQDSMELVHKQSK 430
P +E V ++
Sbjct: 274 KPDSLLETVEHHTE 287
>gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens]
Length = 1205
Score = 48.9 bits (115), Expect = 1e-05
Identities = 62/318 (19%), Positives = 122/318 (38%), Gaps = 47/318 (14%)
Query: 251 DLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPD 310
DL D ++++ A S + ++ W +++ S D S +L+A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSG----VLIAGGENGNIILYDPS 104
Query: 311 GVA-----LVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSN 365
+ +V K T P V + F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 366 KRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLISISTDGKICSWSLDMLSHPQDSME 423
TP++ A T P ++ + Q H L S S G+ W L + +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 424 LVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGH--QGPITG 481
V S + + +++ V+ SE+ + + +M++ P+
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASED----------DRLPVIQMWDLRFASSPLRV 255
Query: 482 IHCHA-AVGAVDFS----HLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTH 536
+ HA + A+ +S L ++ D + + LY N + +D+ W P +
Sbjct: 256 LENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRN 315
Query: 537 PALFACVDGMGRLDLWNL 554
PA+ + GR+ ++++
Sbjct: 316 PAVLSAASFDGRISVYSI 333
>gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens]
Length = 1220
Score = 48.9 bits (115), Expect = 1e-05
Identities = 62/318 (19%), Positives = 122/318 (38%), Gaps = 47/318 (14%)
Query: 251 DLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPD 310
DL D ++++ A S + ++ W +++ S D S +L+A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSG----VLIAGGENGNIILYDPS 104
Query: 311 GVA-----LVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSN 365
+ +V K T P V + F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 366 KRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLISISTDGKICSWSLDMLSHPQDSME 423
TP++ A T P ++ + Q H L S S G+ W L + +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 424 LVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGH--QGPITG 481
V S + + +++ V+ SE+ + + +M++ P+
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASED----------DRLPVIQMWDLRFASSPLRV 255
Query: 482 IHCHA-AVGAVDFS----HLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTH 536
+ HA + A+ +S L ++ D + + LY N + +D+ W P +
Sbjct: 256 LENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRN 315
Query: 537 PALFACVDGMGRLDLWNL 554
PA+ + GR+ ++++
Sbjct: 316 PAVLSAASFDGRISVYSI 333
>gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens]
Length = 1106
Score = 48.9 bits (115), Expect = 1e-05
Identities = 62/318 (19%), Positives = 122/318 (38%), Gaps = 47/318 (14%)
Query: 251 DLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPD 310
DL D ++++ A S + ++ W +++ S D S +L+A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSG----VLIAGGENGNIILYDPS 104
Query: 311 GVA-----LVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSN 365
+ +V K T P V + F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 366 KRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLISISTDGKICSWSLDMLSHPQDSME 423
TP++ A T P ++ + Q H L S S G+ W L + +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 424 LVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGH--QGPITG 481
V S + + +++ V+ SE+ + + +M++ P+
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASED----------DRLPVIQMWDLRFASSPLRV 255
Query: 482 IHCHA-AVGAVDFS----HLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTH 536
+ HA + A+ +S L ++ D + + LY N + +D+ W P +
Sbjct: 256 LENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRN 315
Query: 537 PALFACVDGMGRLDLWNL 554
PA+ + GR+ ++++
Sbjct: 316 PAVLSAASFDGRISVYSI 333
>gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens]
Length = 1181
Score = 48.9 bits (115), Expect = 1e-05
Identities = 62/318 (19%), Positives = 122/318 (38%), Gaps = 47/318 (14%)
Query: 251 DLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPD 310
DL D ++++ A S + ++ W +++ S D S +L+A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSG----VLIAGGENGNIILYDPS 104
Query: 311 GVA-----LVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSN 365
+ +V K T P V + F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 366 KRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLISISTDGKICSWSLDMLSHPQDSME 423
TP++ A T P ++ + Q H L S S G+ W L + +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 424 LVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGH--QGPITG 481
V S + + +++ V+ SE+ + + +M++ P+
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASED----------DRLPVIQMWDLRFASSPLRV 255
Query: 482 IHCHA-AVGAVDFS----HLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTH 536
+ HA + A+ +S L ++ D + + LY N + +D+ W P +
Sbjct: 256 LENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRN 315
Query: 537 PALFACVDGMGRLDLWNL 554
PA+ + GR+ ++++
Sbjct: 316 PAVLSAASFDGRISVYSI 333
>gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens]
Length = 1220
Score = 48.9 bits (115), Expect = 1e-05
Identities = 62/318 (19%), Positives = 122/318 (38%), Gaps = 47/318 (14%)
Query: 251 DLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPD 310
DL D ++++ A S + ++ W +++ S D S +L+A N ++P
Sbjct: 49 DLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSG----VLIAGGENGNIILYDPS 104
Query: 311 GVA-----LVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSN 365
+ +V K T P V + F NLV G +I +WD +
Sbjct: 105 KIIAGDKEVVIAQNDKHTGP---------VRALDVNIFQTNLVASGANESEIYIWDLNNF 155
Query: 366 KRTPVQRTPLSAAAHTHPVYCVNVVG--TQNAHNLISISTDGKICSWSLDMLSHPQDSME 423
TP++ A T P ++ + Q H L S S G+ W L + +
Sbjct: 156 A------TPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDL----RKNEPII 205
Query: 424 LVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGH--QGPITG 481
V S + + +++ V+ SE+ + + +M++ P+
Sbjct: 206 KVSDHSNRMHCSGLAWHPDVATQMVLASED----------DRLPVIQMWDLRFASSPLRV 255
Query: 482 IHCHA-AVGAVDFS----HLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTH 536
+ HA + A+ +S L ++ D + + LY N + +D+ W P +
Sbjct: 256 LENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRN 315
Query: 537 PALFACVDGMGRLDLWNL 554
PA+ + GR+ ++++
Sbjct: 316 PAVLSAASFDGRISVYSI 333
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 47.0 bits (110), Expect = 5e-05
Identities = 56/267 (20%), Positives = 106/267 (39%), Gaps = 42/267 (15%)
Query: 8 KAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSM 67
+ E+ R+ R + R E+ ++ ER++K +Q+KE + E E++R+E EA
Sbjct: 141 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREA----- 195
Query: 68 GLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWD-TDPSVLQLH 126
+ VS +D D S HW + P +
Sbjct: 196 ----------------------RREVSAHHRTMREDYSDKVKAS---HWSRSPPRPPRER 230
Query: 127 SDSDLGRGPIKLG-------MAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVV 179
+ GR P+K ++ + + R+ + + +E+EEE+++
Sbjct: 231 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 290
Query: 180 APKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSE 239
E EEE+ +++EE ++ + E +E+ +++ SEE +S + R E L
Sbjct: 291 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV--SEEEMS--EDEERENENHLLV 346
Query: 240 QINIFFDYSGRDLEDKEGEIQAGAKLS 266
FD + E+ E E+ G S
Sbjct: 347 VPESRFDRDSGESEEAEEEVGEGTPQS 373
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 47.0 bits (110), Expect = 5e-05
Identities = 56/267 (20%), Positives = 106/267 (39%), Gaps = 42/267 (15%)
Query: 8 KAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSM 67
+ E+ R+ R + R E+ ++ ER++K +Q+KE + E E++R+E EA
Sbjct: 151 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREA----- 205
Query: 68 GLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWD-TDPSVLQLH 126
+ VS +D D S HW + P +
Sbjct: 206 ----------------------RREVSAHHRTMREDYSDKVKAS---HWSRSPPRPPRER 240
Query: 127 SDSDLGRGPIKLG-------MAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVV 179
+ GR P+K ++ + + R+ + + +E+EEE+++
Sbjct: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
Query: 180 APKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSE 239
E EEE+ +++EE ++ + E +E+ +++ SEE +S + R E L
Sbjct: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV--SEEEMS--EDEERENENHLLV 356
Query: 240 QINIFFDYSGRDLEDKEGEIQAGAKLS 266
FD + E+ E E+ G S
Sbjct: 357 VPESRFDRDSGESEEAEEEVGEGTPQS 383
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 47.0 bits (110), Expect = 5e-05
Identities = 56/267 (20%), Positives = 106/267 (39%), Gaps = 42/267 (15%)
Query: 8 KAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSM 67
+ E+ R+ R + R E+ ++ ER++K +Q+KE + E E++R+E EA
Sbjct: 142 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREA----- 196
Query: 68 GLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWD-TDPSVLQLH 126
+ VS +D D S HW + P +
Sbjct: 197 ----------------------RREVSAHHRTMREDYSDKVKAS---HWSRSPPRPPRER 231
Query: 127 SDSDLGRGPIKLG-------MAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVV 179
+ GR P+K ++ + + R+ + + +E+EEE+++
Sbjct: 232 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 291
Query: 180 APKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSE 239
E EEE+ +++EE ++ + E +E+ +++ SEE +S + R E L
Sbjct: 292 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV--SEEEMS--EDEERENENHLLV 347
Query: 240 QINIFFDYSGRDLEDKEGEIQAGAKLS 266
FD + E+ E E+ G S
Sbjct: 348 VPESRFDRDSGESEEAEEEVGEGTPQS 374
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 47.0 bits (110), Expect = 5e-05
Identities = 56/267 (20%), Positives = 106/267 (39%), Gaps = 42/267 (15%)
Query: 8 KAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSM 67
+ E+ R+ R + R E+ ++ ER++K +Q+KE + E E++R+E EA
Sbjct: 119 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREA----- 173
Query: 68 GLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWD-TDPSVLQLH 126
+ VS +D D S HW + P +
Sbjct: 174 ----------------------RREVSAHHRTMREDYSDKVKAS---HWSRSPPRPPRER 208
Query: 127 SDSDLGRGPIKLG-------MAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVV 179
+ GR P+K ++ + + R+ + + +E+EEE+++
Sbjct: 209 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 268
Query: 180 APKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSE 239
E EEE+ +++EE ++ + E +E+ +++ SEE +S + R E L
Sbjct: 269 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV--SEEEMS--EDEERENENHLLV 324
Query: 240 QINIFFDYSGRDLEDKEGEIQAGAKLS 266
FD + E+ E E+ G S
Sbjct: 325 VPESRFDRDSGESEEAEEEVGEGTPQS 351
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 47.0 bits (110), Expect = 5e-05
Identities = 56/267 (20%), Positives = 106/267 (39%), Gaps = 42/267 (15%)
Query: 8 KAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSM 67
+ E+ R+ R + R E+ ++ ER++K +Q+KE + E E++R+E EA
Sbjct: 108 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREA----- 162
Query: 68 GLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWD-TDPSVLQLH 126
+ VS +D D S HW + P +
Sbjct: 163 ----------------------RREVSAHHRTMREDYSDKVKAS---HWSRSPPRPPRER 197
Query: 127 SDSDLGRGPIKLG-------MAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVV 179
+ GR P+K ++ + + R+ + + +E+EEE+++
Sbjct: 198 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 257
Query: 180 APKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSE 239
E EEE+ +++EE ++ + E +E+ +++ SEE +S + R E L
Sbjct: 258 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV--SEEEMS--EDEERENENHLLV 313
Query: 240 QINIFFDYSGRDLEDKEGEIQAGAKLS 266
FD + E+ E E+ G S
Sbjct: 314 VPESRFDRDSGESEEAEEEVGEGTPQS 340
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 47.0 bits (110), Expect = 5e-05
Identities = 56/267 (20%), Positives = 106/267 (39%), Gaps = 42/267 (15%)
Query: 8 KAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSM 67
+ E+ R+ R + R E+ ++ ER++K +Q+KE + E E++R+E EA
Sbjct: 153 RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREA----- 207
Query: 68 GLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWD-TDPSVLQLH 126
+ VS +D D S HW + P +
Sbjct: 208 ----------------------RREVSAHHRTMREDYSDKVKAS---HWSRSPPRPPRER 242
Query: 127 SDSDLGRGPIKLG-------MAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVV 179
+ GR P+K ++ + + R+ + + +E+EEE+++
Sbjct: 243 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 302
Query: 180 APKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSE 239
E EEE+ +++EE ++ + E +E+ +++ SEE +S + R E L
Sbjct: 303 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV--SEEEMS--EDEERENENHLLV 358
Query: 240 QINIFFDYSGRDLEDKEGEIQAGAKLS 266
FD + E+ E E+ G S
Sbjct: 359 VPESRFDRDSGESEEAEEEVGEGTPQS 385
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,088,061
Number of Sequences: 37866
Number of extensions: 1413489
Number of successful extensions: 20618
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 409
Number of HSP's successfully gapped in prelim test: 521
Number of HSP's that attempted gapping in prelim test: 10701
Number of HSP's gapped (non-prelim): 7091
length of query: 638
length of database: 18,247,518
effective HSP length: 109
effective length of query: 529
effective length of database: 14,120,124
effective search space: 7469545596
effective search space used: 7469545596
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.