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Search of human proteins with 24234708
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24234708 paired-like homeodomain transcription factor 2
isoform b [Homo sapiens]
(317 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24234708 paired-like homeodomain transcription factor 2 isofo... 646 0.0
gi|24234711 paired-like homeodomain transcription factor 2 isofo... 532 e-151
gi|21361183 paired-like homeodomain transcription factor 2 isofo... 527 e-150
gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 362 e-100
gi|4826912 paired-like homeodomain 3 [Homo sapiens] 298 6e-81
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] 119 4e-27
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 112 6e-25
gi|24497589 aristaless related homeobox [Homo sapiens] 107 1e-23
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 106 3e-23
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 105 4e-23
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 105 7e-23
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 104 9e-23
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 100 2e-21
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 100 3e-21
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 94 1e-19
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 94 1e-19
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 94 1e-19
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 94 1e-19
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens] 94 2e-19
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 94 2e-19
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 93 3e-19
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 93 3e-19
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 93 3e-19
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 93 4e-19
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 91 1e-18
gi|14149760 orthopedia homeobox [Homo sapiens] 91 1e-18
gi|34365783 visual system homeobox 2 [Homo sapiens] 89 5e-18
gi|12707580 paired-like homeobox 2b [Homo sapiens] 87 1e-17
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 87 1e-17
gi|46249382 paired-like homeobox 2a [Homo sapiens] 87 2e-17
>gi|24234708 paired-like homeodomain transcription factor 2 isoform
b [Homo sapiens]
Length = 317
Score = 646 bits (1666), Expect = 0.0
Identities = 317/317 (100%), Positives = 317/317 (100%)
Query: 1 METNCRKLVSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGA 60
METNCRKLVSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGA
Sbjct: 1 METNCRKLVSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGA 60
Query: 61 NEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAV 120
NEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAV
Sbjct: 61 NEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAV 120
Query: 121 WTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWA 180
WTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWA
Sbjct: 121 WTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWA 180
Query: 181 AKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLN 240
AKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLN
Sbjct: 181 AKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLN 240
Query: 241 SLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQ 300
SLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQ
Sbjct: 241 SLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQ 300
Query: 301 NPASNLSACQYAVDRPV 317
NPASNLSACQYAVDRPV
Sbjct: 301 NPASNLSACQYAVDRPV 317
>gi|24234711 paired-like homeodomain transcription factor 2 isoform
a [Homo sapiens]
Length = 271
Score = 532 bits (1371), Expect = e-151
Identities = 271/317 (85%), Positives = 271/317 (85%), Gaps = 46/317 (14%)
Query: 1 METNCRKLVSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGA 60
METNCRKLVSACVQL
Sbjct: 1 METNCRKLVSACVQL--------------------------------------------- 15
Query: 61 NEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAV 120
EKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAV
Sbjct: 16 -EKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAV 74
Query: 121 WTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWA 180
WTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWA
Sbjct: 75 WTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWA 134
Query: 181 AKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLN 240
AKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLN
Sbjct: 135 AKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLN 194
Query: 241 SLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQ 300
SLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQ
Sbjct: 195 SLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQ 254
Query: 301 NPASNLSACQYAVDRPV 317
NPASNLSACQYAVDRPV
Sbjct: 255 NPASNLSACQYAVDRPV 271
>gi|21361183 paired-like homeodomain transcription factor 2 isoform
c [Homo sapiens]
Length = 324
Score = 527 bits (1357), Expect = e-150
Identities = 258/260 (99%), Positives = 258/260 (99%)
Query: 58 PGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREE 117
P A EKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREE
Sbjct: 65 PEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREE 124
Query: 118 IAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYN 177
IAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYN
Sbjct: 125 IAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYN 184
Query: 178 NWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGS 237
NWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGS
Sbjct: 185 NWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGS 244
Query: 238 SLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYA 297
SLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYA
Sbjct: 245 SLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYA 304
Query: 298 SVQNPASNLSACQYAVDRPV 317
SVQNPASNLSACQYAVDRPV
Sbjct: 305 SVQNPASNLSACQYAVDRPV 324
>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
sapiens]
Length = 314
Score = 362 bits (930), Expect = e-100
Identities = 189/274 (68%), Positives = 212/274 (77%), Gaps = 9/274 (3%)
Query: 42 ESRKEAASSKFFPRQHPGANEK--DKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQE 99
E+ +S P + G K + S G GA+DP+KKK+QRRQRTHFTSQQLQE
Sbjct: 44 ENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQE 103
Query: 100 LEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQ 159
LEATFQRNRYPDMS REEIAVWTNLTE RVRVWFKNRRAKWRKRERNQQ +LCK G+ PQ
Sbjct: 104 LEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQ 163
Query: 160 FNGLMQPYDDMY-PGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSIS 218
F+GL+QPY+D+Y GYSYNNWAAK L A LSTKSF FFNSM +PLSSQSMFS P+SIS
Sbjct: 164 FSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSM--SPLSSQSMFSAPSSIS 221
Query: 219 SMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTC 277
SM+M SSM P AV G+P S LNN+NNL+ SLNSA+ ACPY P PY VYRDTC
Sbjct: 222 SMTMPSSMGPGAVPGMPNS---GLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTC 278
Query: 278 NSSLASLRLKAKQHSSFGYASVQNPASNLSACQY 311
NSSLASLRLK+KQHSSFGY +Q PAS L+ACQY
Sbjct: 279 NSSLASLRLKSKQHSSFGYGGLQGPASGLNACQY 312
>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
Length = 302
Score = 298 bits (762), Expect = 6e-81
Identities = 169/297 (56%), Positives = 200/297 (67%), Gaps = 25/297 (8%)
Query: 42 ESRKEAASSKFFPRQHP--------GANEKDKSQQGKNEDVGA-EDPSKKKRQRRQRTHF 92
E+R A S HP G D + + G+ ED S KK+QRRQRTHF
Sbjct: 10 EARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHF 69
Query: 93 TSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELC 152
TSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER+QQAELC
Sbjct: 70 TSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQAELC 129
Query: 153 KNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPF-FNSMNVNPLSSQSMF 211
K F GL+ PY+++YPGYSY NW K L + L+ K+FPF FNS+NV PL+SQ +F
Sbjct: 130 KGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL-APPLAAKTFPFAFNSVNVGPLASQPVF 188
Query: 212 SPPNSI-SSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPY------ 264
SPP+SI +SM S++ P V G PG+ L+ +++S +CPY
Sbjct: 189 SPPSSIAASMVPSAAAAPGTVPG-PGALQGLGGGPPGLAPAAVSSG--AVSCPYASAAAA 245
Query: 265 --APPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQN--PASNLSACQYAVDRPV 317
A + PYVYRD CNSSLASLRLKAKQH+SF Y +V PA+NLS CQYAV+RPV
Sbjct: 246 AAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQYAVERPV 302
>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
Length = 326
Score = 119 bits (298), Expect = 4e-27
Identities = 83/233 (35%), Positives = 122/233 (52%), Gaps = 22/233 (9%)
Query: 63 KDKSQQGKNEDVGAEDPSK--KKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAV 120
K ++G+ +++G + S ++RR RT FTS QL+ELE FQ+ YPD+ RE++A+
Sbjct: 108 KGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLAL 167
Query: 121 WTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWA 180
T LTEARV+VWF+NRRAKWRKRER Q + K+ F ++ + P D YP N WA
Sbjct: 168 RTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWA 227
Query: 181 AKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLN 240
+ +++ P S + P S SP S S+ + + VP
Sbjct: 228 GNASGGSVVTSCMLPRDTSSCMTPYS----HSPRTDSSYTGFSNHQ--NQFSHVP----- 276
Query: 241 SLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS 293
LNN + SL + +A T P R +SS+A LR+KAK+H++
Sbjct: 277 ----LNNFFTDSLLTGATN---GHAFETKPEFERR--SSSIAVLRMKAKEHTA 320
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 112 bits (279), Expect = 6e-25
Identities = 81/223 (36%), Positives = 114/223 (51%), Gaps = 27/223 (12%)
Query: 76 AEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKN 135
A+ S K ++RR RT FTS QL+ELE FQ+ YPD+ RE++A+ T+LTEARV+VWF+N
Sbjct: 205 ADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQN 264
Query: 136 RRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMY-----PGYSYNNWAAKGLTSASLS 190
RRAKWRKRER Q + + F + + + Y P + NN AA + + +
Sbjct: 265 RRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVP 324
Query: 191 TKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSS 250
P S + + PP S +S V A + V + + SL +L S
Sbjct: 325 CDPVPACMSPHAH---------PPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASL-S 374
Query: 251 PSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS 293
P LN Y P D SS+A+LR+KAK+HS+
Sbjct: 375 PGLNG--------YELNGEP----DRKTSSIAALRMKAKEHSA 405
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 107 bits (267), Expect = 1e-23
Identities = 83/233 (35%), Positives = 126/233 (54%), Gaps = 22/233 (9%)
Query: 76 AEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKN 135
+E+ K++QRR RT FTS QL+ELE FQ+ YPD+ TREE+A+ +LTEARV+VWF+N
Sbjct: 319 SEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQN 378
Query: 136 RRAKWRKRERNQQAELCKNGF---GP-QFNGLMQPYDDMYPGYSYNNWAAKGLTSASLST 191
RRAKWRKRE+ A+ G GP + PY D P ++ T+A+ +
Sbjct: 379 RRAKWRKREK-AGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAA 437
Query: 192 KSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSM------VPSAVTGVPGSSLNSLNNL 245
+ F S+ P S+ S P S + + +S+ + P+ ++ G +++ L
Sbjct: 438 AA--AFPSLPPPPGSA----SLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPL 491
Query: 246 NNLSSPSLNSAVPTPACPYAPPT-----PPYVYRDTCNSSLASLRLKAKQHSS 293
+ S+ + PTPA A + P D SS+A+LRLKAK+H++
Sbjct: 492 TSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAA 544
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 106 bits (264), Expect = 3e-23
Identities = 98/330 (29%), Positives = 144/330 (43%), Gaps = 50/330 (15%)
Query: 25 LFSKDSEIKKVEFTDSPES----RKEAASSKFFPRQHPGANEKDKSQQGKNEDVGAE-DP 79
L S S + +++F E +KE K G ++ + DV +E D
Sbjct: 152 LVSSISRVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDL 211
Query: 80 SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 139
K++QRR RT FT++QL+ELE F+R YPD+ TREE+A T LTEARV+VWF NRRA+
Sbjct: 212 PLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRAR 271
Query: 140 WRKRE-RNQQA---ELCKNGFGPQFNGLMQPY---DDMYPGYSYNN-------------- 178
WRK+ NQ A L GF P + PY D YP + +
Sbjct: 272 WRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPP 331
Query: 179 -----------WAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSP-PNSISSMSMSSSM 226
AA +SA + SF ++ +NP + + +P N +S MS
Sbjct: 332 STMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILG 391
Query: 227 VPSAVTGVPGS---------SLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTC 277
PSAV P + L+S +++ S +S P + P + P Y T
Sbjct: 392 NPSAVPPQPQADFSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPTYSTT- 450
Query: 278 NSSLASLRLKAKQHSSFGYASVQNPASNLS 307
+ + Q+ +G +V A N+S
Sbjct: 451 --GYSVDPVAGYQYGQYGQTAVDYLAKNVS 478
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 105 bits (263), Expect = 4e-23
Identities = 93/295 (31%), Positives = 132/295 (44%), Gaps = 51/295 (17%)
Query: 25 LFSKDSEIKKVEFTDSPES----RKEAASSKFFPRQHPGANEKDKSQQGKNEDVGAE-DP 79
L S S + +++F E +KE K G ++ + DV +E D
Sbjct: 152 LVSSISRVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDL 211
Query: 80 SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 139
K++QRR RT FT++QL+ELE F+R YPD+ TREE+A T LTEARV+VWF NRRA+
Sbjct: 212 PLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRAR 271
Query: 140 WRKRE-RNQQA---ELCKNGFGPQFNGLMQPY---DDMYPGYSYNN-------------- 178
WRK+ NQ A L GF P + PY D YP + +
Sbjct: 272 WRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPP 331
Query: 179 -----------WAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSP-PNSISSMSMSSSM 226
AA +SA + SF ++ +NP + + +P N +S MS
Sbjct: 332 STMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILG 391
Query: 227 VPSAVTGVPGS---------SLNSLNNLNNLSSPSLNSAVPTPACP----YAPPT 268
PSAV P + L+S +++ S +S P + P Y PPT
Sbjct: 392 NPSAVPPQPQADFSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPT 446
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 105 bits (261), Expect = 7e-23
Identities = 74/232 (31%), Positives = 110/232 (47%), Gaps = 39/232 (16%)
Query: 69 GKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR 128
G + +D +++QRR RT FT QQL+ LEA F + YPD+ TREE+A+ NLTEAR
Sbjct: 22 GNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEAR 81
Query: 129 VRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS 188
V+VWF+NRRAKWRK ER G Q G +P ++ P
Sbjct: 82 VQVWFQNRRAKWRKTER---------GASDQEPGAKEPMAEVTP---------------- 116
Query: 189 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSA---VTGVPGSSLNSLNNL 245
P ++N P Q+ + S+ ++ P+ + +PG+ LN+
Sbjct: 117 ------PPVRNINSPPPGDQARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYA 170
Query: 246 NNLSSPSLNSAVPTPACPYAPP-----TPPYVYRDTCNSSLASLRLKAKQHS 292
LS + P +C P P Y + +S+A+LR+KA++HS
Sbjct: 171 QALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHS 222
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 104 bits (260), Expect = 9e-23
Identities = 92/293 (31%), Positives = 131/293 (44%), Gaps = 51/293 (17%)
Query: 27 SKDSEIKKVEFTDSPES----RKEAASSKFFPRQHPGANEKDKSQQGKNEDVGAE-DPSK 81
S S + +++F E +KE K G ++ + DV +E D
Sbjct: 152 SSISRVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPL 211
Query: 82 KKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWR 141
K++QRR RT FT++QL+ELE F+R YPD+ TREE+A T LTEARV+VWF NRRA+WR
Sbjct: 212 KRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWR 271
Query: 142 KRE-RNQQA---ELCKNGFGPQFNGLMQPY---DDMYPGYSYNN---------------- 178
K+ NQ A L GF P + PY D YP + +
Sbjct: 272 KQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPST 331
Query: 179 ---------WAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSP-PNSISSMSMSSSMVP 228
AA +SA + SF ++ +NP + + +P N +S MS P
Sbjct: 332 MHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSNGLSPQVMSILGNP 391
Query: 229 SAVTGVPGS---------SLNSLNNLNNLSSPSLNSAVPTPACP----YAPPT 268
SAV P + L+S +++ S +S P + P Y PPT
Sbjct: 392 SAVPPQPQADFSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQAYCPPT 444
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 100 bits (249), Expect = 2e-21
Identities = 48/102 (47%), Positives = 70/102 (68%)
Query: 82 KKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWR 141
K ++RR RT F++ QL+ELE FQ+ YPD+ RE++A+ T+LTEARV+VWF+NRRAKWR
Sbjct: 150 KSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWR 209
Query: 142 KRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKG 183
KRER + + +N F ++ + P D +P + WA+ G
Sbjct: 210 KRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPG 251
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 99.8 bits (247), Expect = 3e-21
Identities = 76/231 (32%), Positives = 106/231 (45%), Gaps = 37/231 (16%)
Query: 76 AEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKN 135
+E+ KK+ RR RT FT+ QL ELE F+++ YPD+ +REE+A NL E RV+VWF+N
Sbjct: 127 SEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQN 186
Query: 136 RRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSF- 194
RRAKWR++E+ + + + K P + P + G +L +S+
Sbjct: 187 RRAKWRRQEKLEVSSM-KLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLESWL 245
Query: 195 -PFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSL 253
P L S F PP + +P++ T P P L
Sbjct: 246 GPPLPGGGATALQSLPGFGPP---------AQSLPASYTPPPP------------PPPFL 284
Query: 254 NSAVPTPAC-PYAPPTPPYV------------YRDTCNSSLASLRLKAKQH 291
NS P P APP P Y D NSS+A+LRLKAK+H
Sbjct: 285 NSPPLGPGLQPLAPPPPSYPCGPGFGDKFPLDEADPRNSSIAALRLKAKEH 335
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 94.4 bits (233), Expect = 1e-19
Identities = 81/257 (31%), Positives = 113/257 (43%), Gaps = 26/257 (10%)
Query: 30 SEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKS---QQGKNEDVGAE-DPSKKKRQ 85
S+ K E ++ RKEA S+ + +++ Q + D+ +E D K++Q
Sbjct: 159 SKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQ 218
Query: 86 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 145
RR RT FT++QL+ELE F+R YPD+ TREE+A LTEARV+VWF NRRA+WRK+
Sbjct: 219 RRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG 278
Query: 146 NQQA----ELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFP------ 195
Q L GF P + Y SY + S ST P
Sbjct: 279 ANQLMAFNHLIPGGFPPTAMPTLPTY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS 336
Query: 196 --FFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNL--NNLSSP 251
+++ NP SS + P S + S VP P N +N N LS
Sbjct: 337 TVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQ 390
Query: 252 SLNSAVPTPACPYAPPT 268
+ P+ P T
Sbjct: 391 VMGLLTNHGGVPHQPQT 407
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 94.4 bits (233), Expect = 1e-19
Identities = 81/257 (31%), Positives = 113/257 (43%), Gaps = 26/257 (10%)
Query: 30 SEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKS---QQGKNEDVGAE-DPSKKKRQ 85
S+ K E ++ RKEA S+ + +++ Q + D+ +E D K++Q
Sbjct: 160 SKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQ 219
Query: 86 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 145
RR RT FT++QL+ELE F+R YPD+ TREE+A LTEARV+VWF NRRA+WRK+
Sbjct: 220 RRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG 279
Query: 146 NQQA----ELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFP------ 195
Q L GF P + Y SY + S ST P
Sbjct: 280 ANQLMAFNHLIPGGFPPTAMPTLPTY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS 337
Query: 196 --FFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNL--NNLSSP 251
+++ NP SS + P S + S VP P N +N N LS
Sbjct: 338 TVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQ 391
Query: 252 SLNSAVPTPACPYAPPT 268
+ P+ P T
Sbjct: 392 VMGLLTNHGGVPHQPQT 408
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 94.4 bits (233), Expect = 1e-19
Identities = 81/257 (31%), Positives = 113/257 (43%), Gaps = 26/257 (10%)
Query: 30 SEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKS---QQGKNEDVGAE-DPSKKKRQ 85
S+ K E ++ RKEA S+ + +++ Q + D+ +E D K++Q
Sbjct: 160 SKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQ 219
Query: 86 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 145
RR RT FT++QL+ELE F+R YPD+ TREE+A LTEARV+VWF NRRA+WRK+
Sbjct: 220 RRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG 279
Query: 146 NQQA----ELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFP------ 195
Q L GF P + Y SY + S ST P
Sbjct: 280 ANQLMAFNHLIPGGFPPTAMPTLPTY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS 337
Query: 196 --FFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNL--NNLSSP 251
+++ NP SS + P S + S VP P N +N N LS
Sbjct: 338 TVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQ 391
Query: 252 SLNSAVPTPACPYAPPT 268
+ P+ P T
Sbjct: 392 VMGLLTNHGGVPHQPQT 408
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 94.4 bits (233), Expect = 1e-19
Identities = 81/257 (31%), Positives = 113/257 (43%), Gaps = 26/257 (10%)
Query: 30 SEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKS---QQGKNEDVGAE-DPSKKKRQ 85
S+ K E ++ RKEA S+ + +++ Q + D+ +E D K++Q
Sbjct: 160 SKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQ 219
Query: 86 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 145
RR RT FT++QL+ELE F+R YPD+ TREE+A LTEARV+VWF NRRA+WRK+
Sbjct: 220 RRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG 279
Query: 146 NQQA----ELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFP------ 195
Q L GF P + Y SY + S ST P
Sbjct: 280 ANQLMAFNHLIPGGFPPTAMPTLPTY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS 337
Query: 196 --FFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNL--NNLSSP 251
+++ NP SS + P S + S VP P N +N N LS
Sbjct: 338 TVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQ 391
Query: 252 SLNSAVPTPACPYAPPT 268
+ P+ P T
Sbjct: 392 VMGLLTNHGGVPHQPQT 408
>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
Length = 217
Score = 94.0 bits (232), Expect = 2e-19
Identities = 50/106 (47%), Positives = 67/106 (63%), Gaps = 5/106 (4%)
Query: 56 QHPGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTR 115
+ PG + Q N+ + +E+ KK++QRR RT F S QLQ LE F+R YPD R
Sbjct: 66 ESPGLTSGSDTPQQDNDQLNSEE-KKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVR 124
Query: 116 EEIAVWTNLTEARVRVWFKNRRAKWRKRER----NQQAELCKNGFG 157
E++A NLTEARV+VWF+NRRAK+R+ ER N+ A L K+ G
Sbjct: 125 EDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSG 170
>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
Length = 245
Score = 94.0 bits (232), Expect = 2e-19
Identities = 50/106 (47%), Positives = 67/106 (63%), Gaps = 5/106 (4%)
Query: 56 QHPGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTR 115
+ PG + Q N+ + +E+ KK++QRR RT F S QLQ LE F+R YPD R
Sbjct: 66 ESPGLTSGSDTPQQDNDQLNSEE-KKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVR 124
Query: 116 EEIAVWTNLTEARVRVWFKNRRAKWRKRER----NQQAELCKNGFG 157
E++A NLTEARV+VWF+NRRAK+R+ ER N+ A L K+ G
Sbjct: 125 EDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSG 170
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 93.2 bits (230), Expect = 3e-19
Identities = 78/241 (32%), Positives = 110/241 (45%), Gaps = 25/241 (10%)
Query: 30 SEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKS---QQGKNEDVGAE-DPSKKKRQ 85
S+ K E ++ RKEA S+ + +++ Q + D+ +E D K++Q
Sbjct: 160 SKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQ 219
Query: 86 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 145
RR RT FT++QL+ELE F+R YPD+ TREE+A LTEARV+VWF NRRA+WRK+
Sbjct: 220 RRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG 279
Query: 146 NQQA----ELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFP------ 195
Q L GF P + Y SY + S ST P
Sbjct: 280 ANQLMAFNHLIPGGFPPTAMPTLPTY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS 337
Query: 196 --FFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLN-NLNNLSSPS 252
+++ NP SS + P S + S VP P N +N + N SP
Sbjct: 338 TVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQ 391
Query: 253 L 253
+
Sbjct: 392 V 392
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 93.2 bits (230), Expect = 3e-19
Identities = 78/241 (32%), Positives = 110/241 (45%), Gaps = 25/241 (10%)
Query: 30 SEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKS---QQGKNEDVGAE-DPSKKKRQ 85
S+ K E ++ RKEA S+ + +++ Q + D+ +E D K++Q
Sbjct: 160 SKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQ 219
Query: 86 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 145
RR RT FT++QL+ELE F+R YPD+ TREE+A LTEARV+VWF NRRA+WRK+
Sbjct: 220 RRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG 279
Query: 146 NQQA----ELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFP------ 195
Q L GF P + Y SY + S ST P
Sbjct: 280 ANQLMAFNHLIPGGFPPTAMPTLPTY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS 337
Query: 196 --FFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLN-NLNNLSSPS 252
+++ NP SS + P S + S VP P N +N + N SP
Sbjct: 338 TVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQ 391
Query: 253 L 253
+
Sbjct: 392 V 392
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 93.2 bits (230), Expect = 3e-19
Identities = 47/107 (43%), Positives = 71/107 (66%)
Query: 44 RKEAASSKFFPRQHPGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEAT 103
++ A ++ P P + +++ + + A S+ ++QRR RT FT+QQL+ LE T
Sbjct: 25 QQAAQQAQHAPDYRPSVHALTLAERLADIILEARYGSQHRKQRRSRTAFTAQQLEALEKT 84
Query: 104 FQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAE 150
FQ+ YPD+ RE +A+ TNL EARV+VWFKNRRAK+RK++R+ Q E
Sbjct: 85 FQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKE 131
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 92.8 bits (229), Expect = 4e-19
Identities = 43/71 (60%), Positives = 57/71 (80%)
Query: 80 SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 139
S+ ++QRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRAK
Sbjct: 66 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 125
Query: 140 WRKRERNQQAE 150
+RK++R+ Q E
Sbjct: 126 FRKKQRSLQKE 136
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 91.3 bits (225), Expect = 1e-18
Identities = 83/259 (32%), Positives = 117/259 (45%), Gaps = 48/259 (18%)
Query: 62 EKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVW 121
+K QG A +++Q+R RT FT QL ELE +F + YPD+ REE+A+
Sbjct: 81 DKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALR 140
Query: 122 TNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNGFGPQF----NGLMQPYDDMYP 172
LTE+RV+VWF+NRRAKW+KR++ L PQF D
Sbjct: 141 IGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLC 200
Query: 173 GYSYNN--WAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFS-------PPNSISSMSMS 223
+ N+ WAA + S P ++ +QS+ PPN SM +S
Sbjct: 201 SFHANDTRWAAAAMPGVS----QLPLPPALGRQQAMAQSLSQCSLAAGPPPN---SMGLS 253
Query: 224 SSMVPSAVTGV---------PGSSLNSLNNLNNLS-SPSLNSAVPTPACPYAPPTPPYVY 273
+S+ S G+ PG SL +N+S SP L S+ P V+
Sbjct: 254 NSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGSPQLCSS----------PDSSDVW 303
Query: 274 RDTCNSSLASLRLKAKQHS 292
R T S+ASLR KA +H+
Sbjct: 304 RGT---SIASLRRKALEHT 319
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 91.3 bits (225), Expect = 1e-18
Identities = 83/259 (32%), Positives = 117/259 (45%), Gaps = 48/259 (18%)
Query: 62 EKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVW 121
+K QG A +++Q+R RT FT QL ELE +F + YPD+ REE+A+
Sbjct: 81 DKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALR 140
Query: 122 TNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNGFGPQF----NGLMQPYDDMYP 172
LTE+RV+VWF+NRRAKW+KR++ L PQF D
Sbjct: 141 IGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLC 200
Query: 173 GYSYNN--WAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFS-------PPNSISSMSMS 223
+ N+ WAA + S P ++ +QS+ PPN SM +S
Sbjct: 201 SFHANDTRWAAAAMPGVS----QLPLPPALGRQQAMAQSLSQCSLAAGPPPN---SMGLS 253
Query: 224 SSMVPSAVTGV---------PGSSLNSLNNLNNLS-SPSLNSAVPTPACPYAPPTPPYVY 273
+S+ S G+ PG SL +N+S SP L S+ P V+
Sbjct: 254 NSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGSPQLCSS----------PDSSDVW 303
Query: 274 RDTCNSSLASLRLKAKQHS 292
R T S+ASLR KA +H+
Sbjct: 304 RGT---SIASLRRKALEHT 319
>gi|34365783 visual system homeobox 2 [Homo sapiens]
Length = 361
Score = 89.0 bits (219), Expect = 5e-18
Identities = 44/98 (44%), Positives = 61/98 (62%)
Query: 48 ASSKFFPRQHPGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRN 107
AS Q ++ +D S + A + +KK+++RR RT FTS QL+ELE F
Sbjct: 111 ASGPLDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQLEELEKAFNEA 170
Query: 108 RYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 145
YPD+ RE +A+ T L E R++VWF+NRRAKWRKRE+
Sbjct: 171 HYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREK 208
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 87.4 bits (215), Expect = 1e-17
Identities = 45/78 (57%), Positives = 58/78 (74%), Gaps = 2/78 (2%)
Query: 80 SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 139
++K++QRR RT FTS QL+ELE F YPD+ TREE+A+ +LTEARV+VWF+NRRAK
Sbjct: 93 NEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAK 152
Query: 140 WRKRER--NQQAELCKNG 155
+RK+ER A KNG
Sbjct: 153 FRKQERAAAAAAAAAKNG 170
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 87.4 bits (215), Expect = 1e-17
Identities = 60/189 (31%), Positives = 105/189 (55%), Gaps = 24/189 (12%)
Query: 79 PSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRA 138
P+ ++QRR+RT FT QL LEA F + RYPD+ REE+A+ NL E+RV+VWFKNRRA
Sbjct: 32 PATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRA 91
Query: 139 KWRKRERN----------QQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS 188
K R+++++ +++ + G + +G P P S ++ ++ S+S
Sbjct: 92 KCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTP-----PAVS-SSASSSSSASSS 145
Query: 189 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL 248
+ + + NP+++ S S+S+ + SS P++++ PGS+ S++ L
Sbjct: 146 SANPAAAAAAGLGGNPVAAAS------SLSTPAASSIWSPASIS--PGSAPASVSVPEPL 197
Query: 249 SSPSLNSAV 257
++PS S +
Sbjct: 198 AAPSNTSCM 206
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 87.0 bits (214), Expect = 2e-17
Identities = 42/70 (60%), Positives = 55/70 (78%)
Query: 81 KKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKW 140
+K++QRR RT FTS QL+ELE F YPD+ TREE+A+ +LTEARV+VWF+NRRAK+
Sbjct: 86 EKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKF 145
Query: 141 RKRERNQQAE 150
RK+ER A+
Sbjct: 146 RKQERAASAK 155
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.124 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,271,515
Number of Sequences: 37866
Number of extensions: 619207
Number of successful extensions: 4216
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 320
Number of HSP's successfully gapped in prelim test: 146
Number of HSP's that attempted gapping in prelim test: 3515
Number of HSP's gapped (non-prelim): 780
length of query: 317
length of database: 18,247,518
effective HSP length: 102
effective length of query: 215
effective length of database: 14,385,186
effective search space: 3092814990
effective search space used: 3092814990
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.