Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 24158478
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24158478 dapper 1 isoform 1 [Homo sapiens]
(836 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24158478 dapper 1 isoform 1 [Homo sapiens] 1675 0.0
gi|118498364 dapper 1 isoform 2 [Homo sapiens] 1583 0.0
gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo... 175 2e-43
gi|182507165 thymus expressed gene 3-like [Homo sapiens] 124 5e-28
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 53 1e-06
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 46 2e-04
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 44 5e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 42 0.002
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 42 0.002
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 42 0.002
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 42 0.002
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 42 0.002
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 42 0.002
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 42 0.002
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 42 0.002
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 42 0.003
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] 41 0.004
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 41 0.004
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 41 0.005
gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 41 0.005
gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo sapi... 41 0.005
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap... 40 0.007
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 40 0.007
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 40 0.007
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] 39 0.015
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 39 0.020
gi|189181750 human immunodeficiency virus type I enhancer bindin... 39 0.020
gi|116089331 human immunodeficiency virus type I enhancer bindin... 39 0.020
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 39 0.020
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 39 0.020
>gi|24158478 dapper 1 isoform 1 [Homo sapiens]
Length = 836
Score = 1675 bits (4338), Expect = 0.0
Identities = 836/836 (100%), Positives = 836/836 (100%)
Query: 1 MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY 60
MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY
Sbjct: 1 MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY 60
Query: 61 LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR 120
LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR
Sbjct: 61 LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR 120
Query: 121 RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF 180
RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF
Sbjct: 121 RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF 180
Query: 181 SECLSSCHSSTCFCSPLEATLSLSDGCPKSADLIGLLEYKEGHCEDQASGAVCRSLSTPQ 240
SECLSSCHSSTCFCSPLEATLSLSDGCPKSADLIGLLEYKEGHCEDQASGAVCRSLSTPQ
Sbjct: 181 SECLSSCHSSTCFCSPLEATLSLSDGCPKSADLIGLLEYKEGHCEDQASGAVCRSLSTPQ 240
Query: 241 FNSLDVIADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGN 300
FNSLDVIADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGN
Sbjct: 241 FNSLDVIADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGN 300
Query: 301 HASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRT 360
HASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRT
Sbjct: 301 HASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRT 360
Query: 361 SVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWS 420
SVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWS
Sbjct: 361 SVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWS 420
Query: 421 KESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQ 480
KESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQ
Sbjct: 421 KESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQ 480
Query: 481 LSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDF 540
LSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDF
Sbjct: 481 LSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDF 540
Query: 541 KSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPT 600
KSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPT
Sbjct: 541 KSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPT 600
Query: 601 VREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGH 660
VREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGH
Sbjct: 601 VREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGH 660
Query: 661 GREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYV 720
GREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYV
Sbjct: 661 GREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYV 720
Query: 721 ASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESG 780
ASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESG
Sbjct: 721 ASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESG 780
Query: 781 GLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 836
GLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV
Sbjct: 781 GLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 836
>gi|118498364 dapper 1 isoform 2 [Homo sapiens]
Length = 799
Score = 1583 bits (4098), Expect = 0.0
Identities = 799/836 (95%), Positives = 799/836 (95%), Gaps = 37/836 (4%)
Query: 1 MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY 60
MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY
Sbjct: 1 MKPSPAGTAKELEPPAPARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEY 60
Query: 61 LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR 120
LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR
Sbjct: 61 LRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRR 120
Query: 121 RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF 180
RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF
Sbjct: 121 RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSLSNSSNSVF 180
Query: 181 SECLSSCHSSTCFCSPLEATLSLSDGCPKSADLIGLLEYKEGHCEDQASGAVCRSLSTPQ 240
SECLSSCHSSTCFCSPLEATLSLSDGCPKSAD
Sbjct: 181 SECLSSCHSSTCFCSPLEATLSLSDGCPKSAD---------------------------- 212
Query: 241 FNSLDVIADVNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGN 300
VNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGN
Sbjct: 213 ---------VNPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGN 263
Query: 301 HASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRT 360
HASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRT
Sbjct: 264 HASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRT 323
Query: 361 SVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWS 420
SVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWS
Sbjct: 324 SVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWS 383
Query: 421 KESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQ 480
KESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQ
Sbjct: 384 KESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQ 443
Query: 481 LSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDF 540
LSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDF
Sbjct: 444 LSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDF 503
Query: 541 KSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPT 600
KSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPT
Sbjct: 504 KSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPT 563
Query: 601 VREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGH 660
VREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGH
Sbjct: 564 VREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGH 623
Query: 661 GREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYV 720
GREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYV
Sbjct: 624 GREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYV 683
Query: 721 ASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESG 780
ASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESG
Sbjct: 684 ASDSEYSAECESLFHSTVVDTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESG 743
Query: 781 GLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 836
GLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV
Sbjct: 744 GLIWSQFVQTLPIQTVTAPDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 799
>gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo
sapiens]
Length = 774
Score = 175 bits (443), Expect = 2e-43
Identities = 241/872 (27%), Positives = 345/872 (39%), Gaps = 176/872 (20%)
Query: 35 GEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGAAAPRAGELLGEAA 94
G A +R+R R A AGL EL+ LR Q+ VRGAL AAP L
Sbjct: 9 GSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCGPHGLHGPE 68
Query: 95 QRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETD 154
Q+ LE + L++QL+ LR++D GL L +LD QIS L+LDV S E L++D
Sbjct: 69 QQ-------LEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDSD 121
Query: 155 SRPSSGFYELSDGASGSLSNSSNSVFSECLS-SCHSSTCFCSPLEATLSLSDGCPKSADL 213
SRPSSGFYE+SDG S SLS S SV S+ +S S S +A S+ D P+S D
Sbjct: 122 SRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVDE 181
Query: 214 IGLLEYKEGHCEDQA--SGAV-----------CRSLSTPQFN------------------ 242
+ ++ E+ A G+V R +ST +
Sbjct: 182 TTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAEL 241
Query: 243 ------SLDVIADV-NPKYQCDLVSKNGNDVYRYPSPLHAVAVQSPMFLLC----LTGNP 291
+D+ V +PKY+ DLVS+ G +VY YPSPLHAVA+QSP+F+L G P
Sbjct: 242 LGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGGP 301
Query: 292 L--REEDRLGNHASDICGGSELDA--VKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQ 347
RE R + I G L+A + + + LW P+ + + Q
Sbjct: 302 SFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGE-------Q 354
Query: 348 KKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPS 407
+ P+ G G + V APG +G + + + G
Sbjct: 355 GPLRHAASPSPQRQGGWSTDGG----GRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMP 410
Query: 408 LN--NGTFSPPKQWSKESKA---------EQAESKRVPLPEGCPSGAASDLQ-SKHLPKT 455
L + S P++ SK S + SK P G + + S+ L K+
Sbjct: 411 LEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKS 470
Query: 456 AKPASQEHARCSAIGTGESPKESAQLSGASPK---ESPSRGPAPPQENKVVQPLKKMSQK 512
PAS A P +A L PK E R P QPL + +
Sbjct: 471 PSPASGHFAH---------PSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRP 521
Query: 513 NSLQGVPPATPPLLSTAFP-----VEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSV 567
P + +P ++ RPAL +++ G S S E +P
Sbjct: 522 EGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCS-ESTLYPMPVLVP------ 574
Query: 568 RLHRGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKA 627
+ V S + AL E L T + A K R+ ++ + + + A
Sbjct: 575 --------LAVAPQESHRTSAQALFPFEASLLT----SVARRKHRRWQSTVEISARARLA 622
Query: 628 SSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISY 687
S PE+ + G P RAG GR ++V + + R+D K SA
Sbjct: 623 SC--------PESNL-GPPRPVARRAGGPL-ARGRPSLVRQDAYTRSDSEPSKHSA---- 668
Query: 688 EEALRRARRGRRENVGLYPAPVPLPYASPYAYVASDSEYSAECESLFHSTVVDTSEDEQS 747
EC+ F S + +TSE E S
Sbjct: 669 -----------------------------------------ECDPRFPSVIPETSEGESS 687
Query: 748 NYTTNCFGDSESSVSEGEFVGESTTTSDSEESGGLI---WSQFVQTLPIQTVTAPDLHNH 804
++TTN FGD ESS S+ E +S D + + G + ++ T + P L
Sbjct: 688 DHTTNRFGDRESSSSDEEGGAQS---RDCDLALGYVAAGHAELAWTQEAPVSSGPLL--S 742
Query: 805 PAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 836
P +IKAS LKKKI RF+ +LK+MT V
Sbjct: 743 PVPKLCRIKASKALKKKIRRFQPTALKVMTMV 774
>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
Length = 629
Score = 124 bits (310), Expect = 5e-28
Identities = 164/579 (28%), Positives = 220/579 (37%), Gaps = 82/579 (14%)
Query: 298 LGNHASDIC---GGSELDAVKTDSSLPSPSSLWSASHPSSSKKMD-GYILSLVQKKTHPV 353
LG D+ GG E ++ ++ PSS P S+ D G+ S + P
Sbjct: 93 LGQQLGDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGP- 151
Query: 354 RTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTF 413
++PR ++ K L G AP V G + S A P+ G G+
Sbjct: 152 --SEPRGIYASERPKSL---GDASPSAPEVV--GARAAVPRSFSAPYPTAG------GSA 198
Query: 414 SPPKQWSKESKAE----------QAESKRVPLPEGCP---------SGAASDLQSKHLPK 454
P S E +A A + R P P G P +G D L +
Sbjct: 199 GPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLR 258
Query: 455 TAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNS 514
+ R S G P+ + P SPS G A P ++ +
Sbjct: 259 RRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERV-------- 310
Query: 515 LQGVPPATPPLLSTAFP------VEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVR 568
G P +P LS A+ PA + S E LVKAQ+IPG Q + R
Sbjct: 311 --GGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATR 368
Query: 569 LHRGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDT--NKKLKK 626
G+ ++ + P +G RE+ RA ++ R + + + +K
Sbjct: 369 --------GLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARK 420
Query: 627 AS-SKGRKSGGGPEAGVPGRPAG--GGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSA 683
AS S+ S G + VP P R R R RRW+S+A
Sbjct: 421 ASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTA 480
Query: 684 EISYEEALRRARRGRRENVGLYPAPVPLPYASP----YAYVASDSEYSAECESLFHSTVV 739
EI + R R V P P P P A Y SDSE SA +
Sbjct: 481 EIDAADGRRVRPRAPAARV---PGPGPSPSAPQRRLLYGCAGSDSECSA-------GRLG 530
Query: 740 DTSEDEQSNYTTNCFGDSESSVSEGEFVGESTTTSDSEESGGLIWSQ--FVQTLPIQTVT 797
+ +G+SESS SEGE S+ +SDS+ SGGL+W Q T
Sbjct: 531 PLGRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGA 590
Query: 798 APDLHNHPAKTFVKIKASHNLKKKILRFRSGSLKLMTTV 836
PAK FVKIKASH LKKKILRFRSGSLK+MTTV
Sbjct: 591 GAGAPAGPAKVFVKIKASHALKKKILRFRSGSLKVMTTV 629
Score = 68.6 bits (166), Expect = 2e-11
Identities = 128/524 (24%), Positives = 185/524 (35%), Gaps = 108/524 (20%)
Query: 40 ERQRTRERQEATLAGLAELEYLRQRQELLVRGALR----GAGGAGAAAPRAGELLGEAAQ 95
ER R R E +LAGL EL +LR+RQE V+ ALR G GGA EA
Sbjct: 12 ERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGA------------EAED 59
Query: 96 RSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDS 155
+E +E+ R+ L + L + +L +Q+ DL L+ LE +S
Sbjct: 60 EEDADE---DEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLE-----SGGLEQES 111
Query: 156 RPSSGFYELSDGASGSLSNSSNSVFSECLSSCHSSTCFCSPL-----------EATLSLS 204
SSGFYE D +S +S S F C S S + L E SL
Sbjct: 112 GRSSGFYE--DPSSTGGPDSPPSTF--CGDSGFSGSSSYGRLGPSEPRGIYASERPKSLG 167
Query: 205 DGCPKSADLIGLLEYKEGHCEDQASGAVCRSLSTPQFNSLDVIADVNPKYQCDLVSKNGN 264
D P + +++G A AV RS S P + P+ +
Sbjct: 168 DASPSAPEVVG------------ARAAVPRSFSAPYPTA---GGSAGPEACSSAERRARA 212
Query: 265 DVYRYPSPLHAVAVQSPMFLLCLTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPS 324
+ PSPLHAVA++SP CG D
Sbjct: 213 GPFLTPSPLHAVAMRSPR----------------------PCGRPPTD------------ 238
Query: 325 SLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGV 384
S + + +DGYI +L++++ +PRTS G R SV R P
Sbjct: 239 ---SPDAGGAGRPLDGYISALLRRRRRR-GAGQPRTSPGG-ADGGPRRQNSVRQRPPDAS 293
Query: 385 SQGNSVNLKNSKQACLPSGGIPSLNNGTFSP--PKQWSKESKAEQAESKRVPLPEGCPSG 442
S + +++ L G + S W E+ E A P P P+
Sbjct: 294 PSPGSA--RPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAE 351
Query: 443 A----ASDLQSKHLPKTAKPASQEHARCSAIGTGES-----PKESAQLSGASPKESPSRG 493
A + P + + G S P+E + +G + + + G
Sbjct: 352 GRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASG 411
Query: 494 -PAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERP 536
P+ K + + S V P+ PP TA E RP
Sbjct: 412 RRGSPRARKASRSQSETSLLGRASAV-PSGPPKYPTAEREEPRP 454
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 52.8 bits (125), Expect = 1e-06
Identities = 83/353 (23%), Positives = 136/353 (38%), Gaps = 47/353 (13%)
Query: 379 RAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEG 438
R+ G SQ V S Q S P T +P +Q S+ + + +SK P
Sbjct: 1536 RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRR 1595
Query: 439 CPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPS------R 492
SG++ +++ K P+ A A G+ SP+ A A P+ S S R
Sbjct: 1596 SRSGSSPEVKDK--PRAAPRAQS--------GSDSSPEPKAPAPRALPRRSRSGSSSKGR 1645
Query: 493 GPAP----PQENKVVQPLKKMSQKNSLQGVP-----PATPP--LLSTAFPVEERPA-LDF 540
GP+P E+ P K + + + P TPP S + P R A L
Sbjct: 1646 GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSR 1705
Query: 541 KSEGSSQSLEEAHLV-----KAQFIPGQQPS--VRLHRGHRNMGVVKNSSLKHRG----P 589
+S +S S E ++ + +P+ R R R+ + + RG P
Sbjct: 1706 RSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSP 1765
Query: 590 ALQGLENGLP-TVREKTRAGSKKCRFPDDLDTNKKLKKASSKG-----RKSGGGPEAGVP 643
+GL+ + REKTR ++ R T+++ +++ S+ R+ G G + P
Sbjct: 1766 KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP 1825
Query: 644 GRPAGGGHRAGSRAHGHGREAVVAKPKHK-RTDYRRWKSSAEISYEEALRRAR 695
R + R G R ++ + + RT WK S + RR+R
Sbjct: 1826 ARQE-SSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR 1877
Score = 44.7 bits (104), Expect = 4e-04
Identities = 68/312 (21%), Positives = 112/312 (35%), Gaps = 54/312 (17%)
Query: 406 PSLNNGTFSPPKQWS-KESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHA 464
P LNN +P ++ S ES +Q R PL + SG++ +L KP++
Sbjct: 1503 PELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELD-------VKPSASPQE 1555
Query: 465 RCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPP 524
R + + +S ++ +P SR + P+ V ++S + S G P
Sbjct: 1556 RSESDSSPDSKAKT-----RTPLRQRSRSGSSPE----VDSKSRLSPRRSRSGSSP---- 1602
Query: 525 LLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSL 584
V+++P +++ S S E + +P + S SS
Sbjct: 1603 ------EVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS--------------GSSS 1642
Query: 585 KHRGPALQGLEN--GLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGV 642
K RGP+ +G + P K+R + R + T + + R S PE
Sbjct: 1643 KGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTK---SRTPPRRRSSRSSPELTR 1699
Query: 643 PGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEALRRARRGRRENV 702
R + A S R P+H+R+ AE S RR+ R
Sbjct: 1700 KARLSRRSRSASSSPETRSR----TPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKT 1755
Query: 703 ----GLYPAPVP 710
G P+P P
Sbjct: 1756 TSRRGRSPSPKP 1767
Score = 41.2 bits (95), Expect = 0.004
Identities = 55/268 (20%), Positives = 100/268 (37%), Gaps = 44/268 (16%)
Query: 315 KTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLRNG 374
K S P S S+S P K +++H + P+ P +G + +
Sbjct: 805 KAKSRTPPRRSRSSSSPPPKQKS------KTPSRQSHSSSSPHPKVKSGTPPRQGSITS- 857
Query: 375 SVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFS----------------PPKQ 418
Q N ++ +++C S P L + T S PP+Q
Sbjct: 858 ----------PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQ 907
Query: 419 WSKESKAEQAESKRVPLP-EGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKE 477
S + Q + K + P + SG++S S+ +T S+ + CS + + P+
Sbjct: 908 SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRY 967
Query: 478 SAQLSGASPKESPSRGPAPPQENK--VVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEER 535
S SG+S ++ + PP+++ + P K+ + P P L + P +
Sbjct: 968 SH--SGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQT------PPGPSLSGSKSPCPQE 1019
Query: 536 PALDFKSEGSSQSLEEAHLVKAQFIPGQ 563
+ D + SL VK+ PG+
Sbjct: 1020 KSKDSLVQSCPGSLSLCAGVKSSTPPGE 1047
Score = 32.7 bits (73), Expect = 1.4
Identities = 41/182 (22%), Positives = 67/182 (36%), Gaps = 8/182 (4%)
Query: 388 NSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDL 447
+S + +S + S S ++G+ S + S + KRVP P P A +
Sbjct: 2534 SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREG 2593
Query: 448 QSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLK 507
+ P PA ++ R S+ + S S+ S +S S S + +
Sbjct: 2594 R----PPEPTPAKRKR-RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Query: 508 KMSQKNSLQGVP-PATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPS 566
K Q +P PA+P P S S+SL + + + + P QPS
Sbjct: 2649 PSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR--PSPQPS 2706
Query: 567 VR 568
R
Sbjct: 2707 PR 2708
Score = 32.0 bits (71), Expect = 2.4
Identities = 65/305 (21%), Positives = 105/305 (34%), Gaps = 31/305 (10%)
Query: 417 KQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHAR----CSAIGTG 472
K+ SK+ K +++ S P P+ + ++ S T++ S+ A + G
Sbjct: 237 KRKSKDKKRKRSRST-TPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRS 295
Query: 473 ESPKESAQLSGASPKESP----SRGPAPPQENKVVQPL-----KKMSQKNSLQGVPPATP 523
SP + G +P P ++ P+ P E QP K +K P +P
Sbjct: 296 PSPASGRRGEGDAPFSEPGTTSTQRPSSP-ETATKQPSSPYEDKDKDKKEKSATRPSPSP 354
Query: 524 PLLSTA-FPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMG--VVK 580
ST P P L + GS Q L L + P + S R + +
Sbjct: 355 ERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ 414
Query: 581 NSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLD------TNKKLKKASSKGRKS 634
+SS + P+ Q PT + + S + P ++ K S GR
Sbjct: 415 SSSSESSPPSPQ------PTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAK 468
Query: 635 GGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEIS-YEEALRR 693
+ P R G + G R K H R+ +W+ S + +
Sbjct: 469 RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSP 528
Query: 694 ARRGR 698
RRGR
Sbjct: 529 QRRGR 533
Score = 31.6 bits (70), Expect = 3.2
Identities = 32/131 (24%), Positives = 45/131 (34%), Gaps = 9/131 (6%)
Query: 571 RGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLDTNKKLKKASSK 630
R R V+ S + R PA + +G R R G + R P ++ A
Sbjct: 623 RRSRTRSPVRRRS-RSRSPARR---SGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRS 678
Query: 631 GRKSGGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKRTDYRRWKSSAEISYEEA 690
GR + P R R R R V H RT RR +S + +
Sbjct: 679 GRS-----RSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNK 733
Query: 691 LRRARRGRREN 701
R ++R R N
Sbjct: 734 SRTSQRRSRSN 744
>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
Length = 1044
Score = 45.8 bits (107), Expect = 2e-04
Identities = 69/237 (29%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 19 RGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGG 78
R QR RE+ E + E +ER+ A AELE LRQ+ L +
Sbjct: 740 RASQRCLRQAEELREQLEREKEALGQQERERARQRQRAELEELRQQ--------LEESSS 791
Query: 79 AGAAAPRAGELLG--EAAQRSRLEEKFLEENILLLRK--QLNCLRRRDAGLLNQLQELDK 134
A A RA G E +R ++E L++ + L R+ + R+ +A LLN+ QEL +
Sbjct: 792 ALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRKEEAWLLNREQELRE 851
Query: 135 QISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGS----LSNSSNSVFSECLSSCHSS 190
+I R + LE D + E S+ A+ S L + + SE S
Sbjct: 852 EIRKGRDKEIELVIHRLEADMALAK---EESEKAAESRIKRLRDKYEAELSELEQSERKL 908
Query: 191 TCFCSPLEATLSLSDGCPKSADLIGLLEYKEGHCEDQASGAVCRSLSTPQFNSLDVI 247
CS L+ L ++G ++ L GL+ KE ED + AV LS+ + N VI
Sbjct: 909 QERCSELKGQLGEAEG--ENLRLQGLVRQKERALED--AQAVNEQLSSERSNLAQVI 961
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 44.3 bits (103), Expect = 5e-04
Identities = 86/358 (24%), Positives = 127/358 (35%), Gaps = 43/358 (12%)
Query: 315 KTDSSLPSPSSLWSASHPSSSKKMD-----GYILSLVQKKTH--PVRTNKPRTSVNADPT 367
KTD +P+ + L PS S + + ++++ TH P T A+P+
Sbjct: 324 KTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPS 383
Query: 368 KGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQ 427
K P SQ S +N KQ S + GT S + + S +E
Sbjct: 384 K---------FPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSED 434
Query: 428 AESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPK 487
++S++ P E PS +A + LP+ A A + +S +S S +S
Sbjct: 435 SDSEQTP--EKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDS 492
Query: 488 ES--PSRGPAPPQENKVVQPLKKMSQKNSLQGV-PPATPPLLSTAFPVEERPALDFKSEG 544
E P PAP E K N L V PA PP + E P +S+G
Sbjct: 493 EENEPLETPAPEPEPPTT---NKWQLDNWLTKVSQPAAPPEGPRS---TEPPRRHPESKG 546
Query: 545 SSQSLEEAHLVKAQFIP----GQQPSVRLHRGHRNMGVVKNSSLKHRGPALQ--GLENGL 598
SS S +++ P + P H + S + P Q G +
Sbjct: 547 SSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPK 606
Query: 599 PTVREKTRAGSKKC----RFPDDL------DTNKKLKKASSKGRKSGGGPEAGVPGRP 646
V+ RAGS+ R P L T+K K +KGR P P
Sbjct: 607 KPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVP 664
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1707
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1708 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1762
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1763 EMEVLLASKARAEEESRSTS 1782
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1370 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1429
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1430 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1486
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1487 AQKRQAQEE 1495
Score = 33.9 bits (76), Expect = 0.64
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1772 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1830
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1831 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1890
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1891 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1945
Score = 33.1 bits (74), Expect = 1.1
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2118 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2177
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2178 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2235
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2236 QMEELSKLKARIEAENR 2252
Score = 31.2 bits (69), Expect = 4.2
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2139
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2140 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2198
Query: 147 SEE 149
+
Sbjct: 2199 DHQ 2201
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1652 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1711
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1712 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1766
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1767 EMEVLLASKARAEEESRSTS 1786
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1374 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1433
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1434 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1490
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1491 AQKRQAQEE 1499
Score = 33.9 bits (76), Expect = 0.64
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1776 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1834
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1835 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1894
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1895 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1949
Score = 33.1 bits (74), Expect = 1.1
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2122 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2181
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2182 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2239
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2240 QMEELSKLKARIEAENR 2256
Score = 31.2 bits (69), Expect = 4.2
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2084 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2143
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2144 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2202
Query: 147 SEE 149
+
Sbjct: 2203 DHQ 2205
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1707
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1708 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1762
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1763 EMEVLLASKARAEEESRSTS 1782
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1370 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1429
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1430 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1486
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1487 AQKRQAQEE 1495
Score = 33.9 bits (76), Expect = 0.64
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1772 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1830
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1831 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1890
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1891 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1945
Score = 33.1 bits (74), Expect = 1.1
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2118 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2177
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2178 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2235
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2236 QMEELSKLKARIEAENR 2252
Score = 31.2 bits (69), Expect = 4.2
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2139
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2140 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2198
Query: 147 SEE 149
+
Sbjct: 2199 DHQ 2201
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1616 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1675
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1676 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1730
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1731 EMEVLLASKARAEEESRSTS 1750
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1338 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1397
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1398 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1454
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1455 AQKRQAQEE 1463
Score = 33.9 bits (76), Expect = 0.64
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1740 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1798
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1799 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1858
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1859 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1913
Score = 33.1 bits (74), Expect = 1.1
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2086 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2145
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2146 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2203
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2204 QMEELSKLKARIEAENR 2220
Score = 31.2 bits (69), Expect = 4.2
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2048 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2107
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2108 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2166
Query: 147 SEE 149
+
Sbjct: 2167 DHQ 2169
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1785 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1844
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1845 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1899
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1900 EMEVLLASKARAEEESRSTS 1919
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1507 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1566
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1567 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1623
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1624 AQKRQAQEE 1632
Score = 33.9 bits (76), Expect = 0.64
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1909 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1967
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1968 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 2027
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 2028 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 2082
Score = 33.1 bits (74), Expect = 1.1
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2255 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2314
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2315 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2372
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2373 QMEELSKLKARIEAENR 2389
Score = 32.7 bits (73), Expect = 1.4
Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 17/127 (13%)
Query: 442 GAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESP-SRGPAPPQEN 500
G A Q HLP PAS + R + + + P SP RGP P +E
Sbjct: 78 GIAHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRTPHVQAVQGPLGSPPKRGPLPTEEQ 137
Query: 501 KVVQPLKKMSQKNSLQGVPPATPPLLST-----AFP-VEERPALDFKSEGSSQSLEE--- 551
+V + + L+ V P TP + +T A P E PA D + ++ +
Sbjct: 138 RVYR-------RKELEEVSPETPVVPATTQRTLARPGPEPAPATDERDRVQKKTFTKWVN 190
Query: 552 AHLVKAQ 558
HL+KAQ
Sbjct: 191 KHLIKAQ 197
Score = 31.2 bits (69), Expect = 4.2
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2217 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2276
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2277 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2335
Query: 147 SEE 149
+
Sbjct: 2336 DHQ 2338
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1626 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1685
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1686 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1740
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1741 EMEVLLASKARAEEESRSTS 1760
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1348 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1407
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1408 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1464
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1465 AQKRQAQEE 1473
Score = 33.9 bits (76), Expect = 0.64
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1750 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1808
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1809 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1868
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1869 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1923
Score = 33.1 bits (74), Expect = 1.1
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2096 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2155
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2156 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2213
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2214 QMEELSKLKARIEAENR 2230
Score = 31.2 bits (69), Expect = 4.2
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2058 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2117
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2118 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2176
Query: 147 SEE 149
+
Sbjct: 2177 DHQ 2179
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1634 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1693
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1694 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1748
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1749 EMEVLLASKARAEEESRSTS 1768
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1356 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1415
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1416 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1472
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1473 AQKRQAQEE 1481
Score = 33.9 bits (76), Expect = 0.64
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1758 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1816
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1817 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1876
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1877 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1931
Score = 33.1 bits (74), Expect = 1.1
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2104 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2163
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2164 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2221
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2222 QMEELSKLKARIEAENR 2238
Score = 31.2 bits (69), Expect = 4.2
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2066 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2125
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2126 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2184
Query: 147 SEE 149
+
Sbjct: 2185 DHQ 2187
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 10/140 (7%)
Query: 25 AEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQR---QELLVRGALRGAGGAGA 81
AE + + +A+ E+Q+ +EA G AE + +RQR ++ L + G A
Sbjct: 1675 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1734
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
EL+ R R E + E+ LL ++L L+R A + QEL+ +++ +R
Sbjct: 1735 RLAAEQELI-----RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1789
Query: 142 DVE--KTSEEHLETDSRPSS 159
++E S+ E +SR +S
Sbjct: 1790 EMEVLLASKARAEEESRSTS 1809
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAG 80
E++ E + K +A+ E + ++R + + E Q+Q+ ++ L+ +
Sbjct: 1397 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1456
Query: 81 AAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLR 140
A +A EAA+RSRL +EE I ++R QL R+ G +LQ L + +
Sbjct: 1457 EAEIQAKARQAEAAERSRLR---IEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAE 1513
Query: 141 LDVEKTSEE 149
+ EE
Sbjct: 1514 AQKRQAQEE 1522
Score = 33.9 bits (76), Expect = 0.64
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 39/175 (22%)
Query: 18 ARGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQ------------ 65
AR E+ + + +++ EA+ R R + A L LAE E RQRQ
Sbjct: 1799 ARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAE-EAKRQRQLAEEDAARQRAE 1857
Query: 66 -ELLVRGALRGAGGAGAAAPRAGELL---------------GEAAQRSRLEEKF------ 103
E ++ L G A A L EA QR RLEE+
Sbjct: 1858 AERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKAD 1917
Query: 104 LEENILLLRKQLNCLRRRDAGL----LNQLQELDKQISDLRLDVEKTSEEHLETD 154
+EE + LRK + R GL L Q ++++++I L+ EK + E +
Sbjct: 1918 IEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE 1972
Score = 33.1 bits (74), Expect = 1.1
Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 22 QRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGA 81
+++AE + + R + +A E+ R QEA AE LRQ+Q
Sbjct: 2145 KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2204
Query: 82 AAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRL 141
+A R +LEE ++N LL ++L L+ Q ++++++ +R+
Sbjct: 2205 LRQKAQVEQELTTLRLQLEETDHQKN--LLDEELQRLKAEATEAARQRSQVEEELFSVRV 2262
Query: 142 DVEKTS--EEHLETDSR 156
+E+ S + +E ++R
Sbjct: 2263 QMEELSKLKARIEAENR 2279
Score = 31.2 bits (69), Expect = 4.2
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 34 KGEADTERQRTRERQEATLAGLAELEYLRQRQELLVR-------GALRGAGGAGAAAPRA 86
+GEA+ R+ E +EA + E R++ E R A A AA
Sbjct: 2107 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2166
Query: 87 GELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKT 146
E EAA+R++ E+ L + ++ ++ L Q +++++++ LRL +E+T
Sbjct: 2167 KEAEQEAARRAQAEQAALRQK-QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2225
Query: 147 SEE 149
+
Sbjct: 2226 DHQ 2228
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 41.6 bits (96), Expect = 0.003
Identities = 81/381 (21%), Positives = 143/381 (37%), Gaps = 45/381 (11%)
Query: 353 VRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSV--------------NLKNSKQA 398
V+T+ +T A+P + + APG V + N +NS
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 399 CLPSGGIPSLNNGTFSP------PKQWSKESKAEQ-AESKRVPLPEGCPSGAASDLQSKH 451
+PS+ + P++ S S+ E +E + L + PSG +++
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 452 LPKTAKPASQEHARCSAIG-TGESPKESAQL--SGASPKESPSRGPAPPQEN--KVVQPL 506
P AK + ++ A + G TG S ++ + SG+S +ES S G AP +V++P
Sbjct: 901 AP--AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP 958
Query: 507 KKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQ--FIPGQQ 564
N P ATP A + A + + SS E+ ++ A PG +
Sbjct: 959 LIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIR 1018
Query: 565 PS-VRLHRGHRNM----GVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLD 619
+ V + H + + SS K G + P + + G+ P
Sbjct: 1019 TNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTS 1078
Query: 620 -----TNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGHG----REAVVAKPK 670
TNK K + +++ PE+ + +GS G G + A P
Sbjct: 1079 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDS-SSGSEEDGEGPQGAKSAHTLGPT 1137
Query: 671 HKRTDYRRWKSSAEISYEEAL 691
RT+ +++AE S ++ +
Sbjct: 1138 PSRTETLVEETAAESSEDDVV 1158
Score = 32.7 bits (73), Expect = 1.4
Identities = 59/238 (24%), Positives = 83/238 (34%), Gaps = 32/238 (13%)
Query: 482 SGASPKESPSR--GPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALD 539
S S KESP+R PAP + V +K A PP P EE +
Sbjct: 226 SSVSTKESPARKAAPAPGKVGDVTPQVK-----------GGALPPAKRAKKPEEESES-- 272
Query: 540 FKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLP 599
SE S+S EEA + + +++ K + K PA G
Sbjct: 273 --SEEGSESEEEAPAGTRSQVKASEKILQVRAA---SAPAKGTPGKGATPAPPGKAG--- 324
Query: 600 TVREKTRAG------SKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRA 653
V +T+AG D + KA + + SG + G PA R
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384
Query: 654 GSRAHGHGR--EAVVAKPKHKRTDYRRWKSSAEISYEEALRRAR-RGRRENVGLYPAP 708
G+ G+ AV KR + + S S EEA +A+ G+ V AP
Sbjct: 385 GAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAP 442
Score = 32.0 bits (71), Expect = 2.4
Identities = 56/257 (21%), Positives = 90/257 (35%), Gaps = 13/257 (5%)
Query: 313 AVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLR 372
A +T + P S S+ S S++ +L+Q K + S P K R
Sbjct: 327 ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASA---PAKESPR 383
Query: 373 NGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKR 432
G+ AP G + G +V + + S ++ P Q KA Q +
Sbjct: 384 KGAA--PAPPGKT-GPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 440
Query: 433 VPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSR 492
P E GAA K P A+ + S + ES + L+ + +
Sbjct: 441 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 500
Query: 493 GPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEA 552
G +P V+P M +G P P + A P + + SE SS+ ++
Sbjct: 501 GKSPQ-----VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 553 H--LVKAQFIPGQQPSV 567
V P Q+ S+
Sbjct: 556 SDGEVPTAVAPAQEKSL 572
Score = 30.8 bits (68), Expect = 5.4
Identities = 34/152 (22%), Positives = 60/152 (39%), Gaps = 16/152 (10%)
Query: 396 KQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKT 455
+ A P+ G P T +PP + + A +++K E S + S+
Sbjct: 301 RAASAPAKGTPG-KGATPAPPGK----AGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
Query: 456 AKPASQEHA--RCSAIGTGESPKESAQLSGASPKESPSRGP--APPQENKVVQPLKKMSQ 511
AK Q A + S +G +P + + GA+P GP A Q K + + S+
Sbjct: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
Query: 512 KNSLQGVPPA-------TPPLLSTAFPVEERP 536
++ + PA P + + + P +E P
Sbjct: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
Score = 30.4 bits (67), Expect = 7.1
Identities = 40/188 (21%), Positives = 66/188 (35%), Gaps = 25/188 (13%)
Query: 406 PSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQ--------------SKH 451
P + G P K+ K + ++ + E P+G S ++ +K
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKG 309
Query: 452 LP-KTAKPASQEHARCSAIGT-GESPKESAQLSGASPKESPSRGPAPPQ--------ENK 501
P K A PA A A T P+E ++ S +S PA +
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369
Query: 502 VVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIP 561
V ++++ +G PA P A + + S+ SS+ + AQ P
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 429
Query: 562 -GQQPSVR 568
G+ P VR
Sbjct: 430 SGKAPQVR 437
>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
Length = 1352
Score = 41.2 bits (95), Expect = 0.004
Identities = 78/329 (23%), Positives = 122/329 (37%), Gaps = 36/329 (10%)
Query: 384 VSQGNSVNLKNSKQACLPS--GGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPS 441
V Q +SV+ K+ PS G + T S+ E++ K P S
Sbjct: 992 VDQSDSVDSSPVKEVKAPSHPGSLAKKPESTTKRSPSSKGTSEPEKSLRKGRPALASQES 1051
Query: 442 GAASDLQSKHLPK--TAKPA-SQEHARCSAIGTGE--SPKESAQLSGASPKESPSRGPAP 496
+S S LP + KP+ S+ A S+ G+G SP + +SPK S
Sbjct: 1052 SLSSTSPSSPLPVKVSLKPSRSRSKADSSSRGSGRHSSPAPAQPKKESSPKSQDSVSSPS 1111
Query: 497 PQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALD--FKSEGSSQSLEEAHL 554
PQ+ K L + S + A+ P + FP + D EGS QSL
Sbjct: 1112 PQKQKSASALTYTASSTSAK---KASGPATRSPFPPGKSRTSDHSLSREGSRQSLGSDRA 1168
Query: 555 VKAQFIPGQQPSVRLHRGHRNMGV---VKNSSLKHRGPALQGLENGLPTVREKTRAGSKK 611
P V R G V++SS+ +++GL + +++ K
Sbjct: 1169 SATSTSKPNSPRVSQARAGEGRGAGKHVRSSSMASLRSPSTSIKSGL---KRDSKSEDKG 1225
Query: 612 CRFPDDLDTNKKLKKASSKG------RKSGGGPEAGV----PGRPAGGGHRAGS----RA 657
F K+ ++++ G +K+GG V A GH+ + A
Sbjct: 1226 LSFFKSALRQKETRRSTDLGKTALLSKKAGGSSVKSVCKNTGDDEAERGHQPPASQQPNA 1285
Query: 658 HGHGREAVVAK----PKHKRTDYRRWKSS 682
+ G+E +V K KH R+ KSS
Sbjct: 1286 NTTGKEQLVTKDPASAKHSLLSARKSKSS 1314
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 41.2 bits (95), Expect = 0.004
Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 14/117 (11%)
Query: 40 ERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRL 99
E Q R+ ++ A L E +R+ L+ L E L A ++
Sbjct: 1701 EEQAGRDEEQRLAAELHEQAQALERRASLLAAEL--------------EELRAALEQGER 1746
Query: 100 EEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSR 156
+ E+ +L ++LN L ++ GLLNQ ++L+ ++ L +VE+ ++E E + +
Sbjct: 1747 SRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEK 1803
Score = 31.6 bits (70), Expect = 3.2
Identities = 44/180 (24%), Positives = 65/180 (36%), Gaps = 17/180 (9%)
Query: 11 ELEPPAPARGEQRTAEP-------EGRWREKGEADTERQRTRERQEATLAGLA-ELEYLR 62
E E A AR E++ AE R E G A ++ ++EA L L ELE
Sbjct: 1172 EAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAA 1231
Query: 63 QRQELLVRGALRGAGGAGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRD 122
R E V R A + L Q+ E+ L + L + L R
Sbjct: 1232 LRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAK 1291
Query: 123 AGLLNQLQELDKQISDLRLDVEK---------TSEEHLETDSRPSSGFYELSDGASGSLS 173
A + + Q+S+ ++ VE+ T L+T+S S E + LS
Sbjct: 1292 ASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLS 1351
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 40.8 bits (94), Expect = 0.005
Identities = 80/382 (20%), Positives = 143/382 (37%), Gaps = 46/382 (12%)
Query: 353 VRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSV--------------NLKNSKQA 398
V+T+ +T A+P + + APG V + N +NS
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 399 CLPSGGIPSLNNGTFSP------PKQWSKESKAEQ-AESKRVPLPEGCPSGAASDLQSKH 451
+PS+ + P++ S S+ E +E + L + PSG +++
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAAL 900
Query: 452 LPKTAKPASQEHARCSAIG-TGESPKESAQL--SGASPKESPSRGPAPPQEN--KVVQPL 506
P AK + ++ A + G TG S ++ + SG+S +ES S G AP +V++P
Sbjct: 901 AP--AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP 958
Query: 507 KKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQ--FIPGQQ 564
N P ATP A + A + + SS E+ ++ A PG +
Sbjct: 959 LIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIR 1018
Query: 565 PS-VRLHRGHRNM----GVVKNSSLKHRGPALQGLENGLPTVREKTRAGSKKCRFPDDLD 619
+ V + H + + SS K G + P + + G+ P
Sbjct: 1019 TNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTS 1078
Query: 620 -----TNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGHGREA-----VVAKP 669
TNK K + +++ PE+ + +GS G G + + P
Sbjct: 1079 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDS-SSGSEEDGEGPQGAKSAHTLVGP 1137
Query: 670 KHKRTDYRRWKSSAEISYEEAL 691
RT+ +++AE S ++ +
Sbjct: 1138 TPSRTETLVEETAAESSEDDVV 1159
Score = 32.7 bits (73), Expect = 1.4
Identities = 59/238 (24%), Positives = 83/238 (34%), Gaps = 32/238 (13%)
Query: 482 SGASPKESPSR--GPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALD 539
S S KESP+R PAP + V +K A PP P EE +
Sbjct: 226 SSVSTKESPARKAAPAPGKVGDVTPQVK-----------GGALPPAKRAKKPEEESES-- 272
Query: 540 FKSEGSSQSLEEAHLVKAQFIPGQQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLP 599
SE S+S EEA + + +++ K + K PA G
Sbjct: 273 --SEEGSESEEEAPAGTRSQVKASEKILQVRAA---SAPAKGTPGKGATPAPPGKAG--- 324
Query: 600 TVREKTRAG------SKKCRFPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRA 653
V +T+AG D + KA + + SG + G PA R
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384
Query: 654 GSRAHGHGR--EAVVAKPKHKRTDYRRWKSSAEISYEEALRRAR-RGRRENVGLYPAP 708
G+ G+ AV KR + + S S EEA +A+ G+ V AP
Sbjct: 385 GAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAP 442
Score = 32.0 bits (71), Expect = 2.4
Identities = 56/257 (21%), Positives = 90/257 (35%), Gaps = 13/257 (5%)
Query: 313 AVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLVQKKTHPVRTNKPRTSVNADPTKGLLR 372
A +T + P S S+ S S++ +L+Q K + S P K R
Sbjct: 327 ASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASA---PAKESPR 383
Query: 373 NGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKR 432
G+ AP G + G +V + + S ++ P Q KA Q +
Sbjct: 384 KGAA--PAPPGKT-GPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 440
Query: 433 VPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSR 492
P E GAA K P A+ + S + ES + L+ + +
Sbjct: 441 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 500
Query: 493 GPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEA 552
G +P V+P M +G P P + A P + + SE SS+ ++
Sbjct: 501 GKSPQ-----VKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDS 555
Query: 553 H--LVKAQFIPGQQPSV 567
V P Q+ S+
Sbjct: 556 SDGEVPTAVAPAQEKSL 572
Score = 30.8 bits (68), Expect = 5.4
Identities = 34/152 (22%), Positives = 60/152 (39%), Gaps = 16/152 (10%)
Query: 396 KQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKT 455
+ A P+ G P T +PP + + A +++K E S + S+
Sbjct: 301 RAASAPAKGTPG-KGATPAPPGK----AGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
Query: 456 AKPASQEHA--RCSAIGTGESPKESAQLSGASPKESPSRGP--APPQENKVVQPLKKMSQ 511
AK Q A + S +G +P + + GA+P GP A Q K + + S+
Sbjct: 356 AKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSE 415
Query: 512 KNSLQGVPPA-------TPPLLSTAFPVEERP 536
++ + PA P + + + P +E P
Sbjct: 416 ESDSEEEAPAQAKPSGKAPQVRAASAPAKESP 447
Score = 30.4 bits (67), Expect = 7.1
Identities = 40/188 (21%), Positives = 66/188 (35%), Gaps = 25/188 (13%)
Query: 406 PSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQ--------------SKH 451
P + G P K+ K + ++ + E P+G S ++ +K
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKG 309
Query: 452 LP-KTAKPASQEHARCSAIGT-GESPKESAQLSGASPKESPSRGPAPPQ--------ENK 501
P K A PA A A T P+E ++ S +S PA +
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369
Query: 502 VVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIP 561
V ++++ +G PA P A + + S+ SS+ + AQ P
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 429
Query: 562 -GQQPSVR 568
G+ P VR
Sbjct: 430 SGKAPQVR 437
>gi|47132529 suppression of tumorigenicity 5 isoform 1 [Homo
sapiens]
Length = 1137
Score = 40.8 bits (94), Expect = 0.005
Identities = 48/188 (25%), Positives = 65/188 (34%), Gaps = 23/188 (12%)
Query: 401 PSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPAS 460
P G+P L + +S + K E P+G AS A A
Sbjct: 296 PGRGLPQLPSSCYSVDRGKRKTGTLGSLEE---------PAGGASVSAGSRAVGVAGVAG 346
Query: 461 QEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLK-------KMSQKN 513
+ G+G S K + S + PS+ P N V +P + K +
Sbjct: 347 EAGPPPEREGSG-STKPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSK 405
Query: 514 SLQGVPP-----ATPPLLST-AFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSV 567
G+PP A PPL ST A PV RP D + SQS + A + PS
Sbjct: 406 PSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSS 465
Query: 568 RLHRGHRN 575
G N
Sbjct: 466 PTENGTEN 473
>gi|47132532 suppression of tumorigenicity 5 isoform 1 [Homo
sapiens]
Length = 1137
Score = 40.8 bits (94), Expect = 0.005
Identities = 48/188 (25%), Positives = 65/188 (34%), Gaps = 23/188 (12%)
Query: 401 PSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPAS 460
P G+P L + +S + K E P+G AS A A
Sbjct: 296 PGRGLPQLPSSCYSVDRGKRKTGTLGSLEE---------PAGGASVSAGSRAVGVAGVAG 346
Query: 461 QEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLK-------KMSQKN 513
+ G+G S K + S + PS+ P N V +P + K +
Sbjct: 347 EAGPPPEREGSG-STKPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSK 405
Query: 514 SLQGVPP-----ATPPLLST-AFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSV 567
G+PP A PPL ST A PV RP D + SQS + A + PS
Sbjct: 406 PSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSS 465
Query: 568 RLHRGHRN 575
G N
Sbjct: 466 PTENGTEN 473
>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
sapiens]
Length = 1038
Score = 40.4 bits (93), Expect = 0.007
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 33/161 (20%)
Query: 381 PGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKE-SKAEQAE---------S 430
P G SQG + +QA P P L + F PP+ K S A+ AE
Sbjct: 660 PAGPSQGQTNYAFVPEQARPP----PPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECM 715
Query: 431 KRVPLPEGCPSGAAS---DLQSKHLPKTAKPA--SQEHARCSAIGTGESPKESAQLSG-A 484
+++ P G P+ + S D + + P+ P ++ H + S GE +E++Q G A
Sbjct: 716 RQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGE--EETSQWPGPA 773
Query: 485 SPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPL 525
SP P R P PQ ++ PL VPP + PL
Sbjct: 774 SPPRVPPREPLSPQGSRTPSPL-----------VPPGSSPL 803
>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
sapiens]
Length = 1086
Score = 40.4 bits (93), Expect = 0.007
Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 33/161 (20%)
Query: 381 PGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKE-SKAEQAE---------S 430
P G SQG + +QA P P L + F PP+ K S A+ AE
Sbjct: 738 PAGPSQGQTNYAFVPEQARPP----PPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECM 793
Query: 431 KRVPLPEGCPSGAAS---DLQSKHLPKTAKPA--SQEHARCSAIGTGESPKESAQLSG-A 484
+++ P G P+ + S D + + P+ P ++ H + S GE +E++Q G A
Sbjct: 794 RQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGE--EETSQWPGPA 851
Query: 485 SPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPL 525
SP P R P PQ ++ PL VPP + PL
Sbjct: 852 SPPRVPPREPLSPQGSRTPSPL-----------VPPGSSPL 881
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 40.4 bits (93), Expect = 0.007
Identities = 75/309 (24%), Positives = 119/309 (38%), Gaps = 43/309 (13%)
Query: 316 TDSSLPSPSSLWSASHPSSSKKMDGYI-----LSLVQKKTHPVRTNKPRTSVNADPTKGL 370
++S+ P+P + P SS + + + SLV + H + KPR + P++G
Sbjct: 309 SESTTPAPPT----PRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPK--PSEG- 361
Query: 371 LRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAES 430
P + L ++ P+ PS + G PP Q S++ + E
Sbjct: 362 ---------TPAPRKDPPWITLVQAEPKKKPAPLPPSSSPG---PPSQDSRQVENGGTEE 409
Query: 431 KRVPLPEGC-PSGAASDLQSKHLPKTAK-PASQEHARCSAIGTGES-PKESAQLSGASPK 487
P P S + + + K + PA+ A A+G ES PK G +P
Sbjct: 410 VAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPT 469
Query: 488 ESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQ 547
SP P PL + + S P ATP S A VE SE +SQ
Sbjct: 470 SSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATP---SPALSVE-----SLSSESASQ 521
Query: 548 SLEEAHLVKAQFIP--GQQPSVRLHRGHRN-MGVVKNSSLKHRG----PALQGLENGLPT 600
+ A L++ +P +P+V N + + NSSL G P ++ + P
Sbjct: 522 T-AGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPG 580
Query: 601 VREKTRAGS 609
+ +TR S
Sbjct: 581 LAPRTRGSS 589
Score = 32.0 bits (71), Expect = 2.4
Identities = 41/140 (29%), Positives = 54/140 (38%), Gaps = 20/140 (14%)
Query: 411 GTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAKPASQEHARCSAIG 470
G FS PKQ ++ AE A+ +P G PS +A PK A P ++
Sbjct: 232 GPFSQPKQQHQQQLAEDAKD----VPGGGPSSSAPAGAEADGPK-ASPEARPQIPTKPRV 286
Query: 471 TGESPKESAQLSG----ASPKESPSRGPAPP---------QENKVVQPLKKMSQKNSLQG 517
G+ + ++ +G A K S S PAPP QEN V Q L
Sbjct: 287 PGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHE 346
Query: 518 VPPATPPLLSTAFPVEERPA 537
+P P T P E PA
Sbjct: 347 LP--VPKPRGTPKPSEGTPA 364
Score = 32.0 bits (71), Expect = 2.4
Identities = 36/151 (23%), Positives = 52/151 (34%), Gaps = 25/151 (16%)
Query: 396 KQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKT 455
K + P+ P S S S E E + +P+ P G A + P+
Sbjct: 535 KSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASP-GLAPRTRGSSGPQP 593
Query: 456 AKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQE-----------NKVVQ 504
AKP S G +P + SP SP G + PQ N+
Sbjct: 594 AKPCS-----------GATPTPLLLVGDRSPVPSP--GSSSPQLQVKSSCKENPFNRKPS 640
Query: 505 PLKKMSQKNSLQGVPPATPPLLSTAFPVEER 535
P + K + +G P PP FP+ +R
Sbjct: 641 PAASPATKKATKGSKPVRPPAPGHGFPLIKR 671
>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
Length = 1080
Score = 39.3 bits (90), Expect = 0.015
Identities = 70/251 (27%), Positives = 112/251 (44%), Gaps = 20/251 (7%)
Query: 10 KELEPPAPARGEQRTAEPEGRWREKGEADT-ERQRTRERQEATLAGLAEL---EYLRQRQ 65
++LE A G+Q R+++ E + Q+ R+R + +A E + RQR
Sbjct: 754 EQLEREKEALGQQERERARQRFQQHLEQEQWALQQQRQRLYSEVAEERERLGQQAARQRA 813
Query: 66 ELL-VRGALRGAGGAGAAAPRAGELLG--EAAQRSRLEEKFLEENILLLRK--QLNCLRR 120
EL +R L + A A RA G E +R ++E L++ + L R+ + R+
Sbjct: 814 ELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRK 873
Query: 121 RDAGLLNQLQELDKQISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGS----LSNSS 176
+A LLN+ QEL ++I R + LE D + E S+ A+ S L +
Sbjct: 874 EEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAK---EESEKAAESRIKRLRDKY 930
Query: 177 NSVFSECLSSCHSSTCFCSPLEATLSLSDGCPKSADLIGLLEYKEGHCEDQASGAVCRSL 236
+ SE S CS L+ L ++G ++ L GL+ KE ED + AV L
Sbjct: 931 EAELSELEQSERKLQERCSELKGQLGEAEG--ENLRLQGLVRQKERALED--AQAVNEQL 986
Query: 237 STPQFNSLDVI 247
S+ + N VI
Sbjct: 987 SSERSNLAQVI 997
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 38.9 bits (89), Expect = 0.020
Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 10/157 (6%)
Query: 21 EQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQE-LLVRGALRGAGGA 79
E+R E E R RE+ E E++ QE L + E LR+++E L + L G
Sbjct: 282 EERLCEQEERLREQEERLCEQEERLREQEERLC--EQEERLREQEERLCEQEKLPGQERL 339
Query: 80 GAAAPRAGELLGEAAQRSRL--EEKFLEENILLLRKQLNCLRRRDAGLLNQ--LQELDKQ 135
+ E ++ RL E+ LEE LL ++ LR++D L Q LQEL++
Sbjct: 340 LEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQER--LRQQDERLWQQETLQELER- 396
Query: 136 ISDLRLDVEKTSEEHLETDSRPSSGFYELSDGASGSL 172
+ +L +E E E + P SGF EL++ +L
Sbjct: 397 LRELERMLELGWEALYEQRAEPRSGFEELNNENKSTL 433
Score = 32.0 bits (71), Expect = 2.4
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 3/131 (2%)
Query: 19 RGEQRTAEPEGRWREKGEADTERQRTRERQEATLAGLAELEYLRQRQELLVRGALRGAGG 78
R E+R E E R RE+ E E++ QE L + E LR+++E L R
Sbjct: 196 RQEERLREQEERLREQEERLREQEERLCEQEERLR--EQEERLREQEERLCEQEERLREH 253
Query: 79 AGAAAPRAGELLGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISD 138
+ E L E +R R +E+ L E L +Q LR ++ L Q + L +Q
Sbjct: 254 EERLCEQE-ERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEER 312
Query: 139 LRLDVEKTSEE 149
L E+ E+
Sbjct: 313 LCEQEERLREQ 323
>gi|189181750 human immunodeficiency virus type I enhancer binding
protein 3 b [Homo sapiens]
Length = 2405
Score = 38.9 bits (89), Expect = 0.020
Identities = 95/479 (19%), Positives = 170/479 (35%), Gaps = 64/479 (13%)
Query: 287 LTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLV 346
+ G ++ D H C ++ + + SP + S +M Y L
Sbjct: 647 ICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTT 706
Query: 347 QKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIP 406
+ T P+R + S+ + + +PG ++ L+++K PS +P
Sbjct: 707 LELT-PLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVP 765
Query: 407 SLNNGT-FSP----PKQWSKESKAEQAESKRVPLPEGCPSGAASDL---------QSKHL 452
SL T F P P S+ K + SK + + + S SD + K L
Sbjct: 766 SLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPL 825
Query: 453 PKTAKPASQEHARCS-AIGTGESPKESAQLSGASPKESPSRGPA----PPQENKVVQPLK 507
+ P H R + ++ + + Q+ E P R PP+E + + +
Sbjct: 826 AQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQ 885
Query: 508 KMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSV 567
+ +L +P P P ++R L ++ S +S E+ V P Q+ +V
Sbjct: 886 WPQRSQTLAQLPAEKLP------PKKKRLRLAEMAQSSGESSFESS-VPLSRSPSQESNV 938
Query: 568 RLHRGHRNMGVVKNSSLKHRGPA-------------LQGLENGLPTVREKTRAGSKKC-R 613
L R+ ++ K P+ + + + P RE R+ S++
Sbjct: 939 SLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN 998
Query: 614 FPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKR 673
+ K+ G S GP A P P A VA P+ ++
Sbjct: 999 VSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAP----------------PARVAPPERRK 1042
Query: 674 TDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYVASDSEYSAECES 732
R ++S E L A +GR+E + P P +S + +S S+ S+ S
Sbjct: 1043 CFLVR-QASLSRPPESELEVAPKGRQE------SEEPQPSSSKPSAKSSLSQISSAATS 1094
>gi|116089331 human immunodeficiency virus type I enhancer binding
protein 3 [Homo sapiens]
Length = 2406
Score = 38.9 bits (89), Expect = 0.020
Identities = 95/479 (19%), Positives = 170/479 (35%), Gaps = 64/479 (13%)
Query: 287 LTGNPLREEDRLGNHASDICGGSELDAVKTDSSLPSPSSLWSASHPSSSKKMDGYILSLV 346
+ G ++ D H C ++ + + SP + S +M Y L
Sbjct: 647 ICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTT 706
Query: 347 QKKTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVSQGNSVNLKNSKQACLPSGGIP 406
+ T P+R + S+ + + +PG ++ L+++K PS +P
Sbjct: 707 LELT-PLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVP 765
Query: 407 SLNNGT-FSP----PKQWSKESKAEQAESKRVPLPEGCPSGAASDL---------QSKHL 452
SL T F P P S+ K + SK + + + S SD + K L
Sbjct: 766 SLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPL 825
Query: 453 PKTAKPASQEHARCS-AIGTGESPKESAQLSGASPKESPSRGPA----PPQENKVVQPLK 507
+ P H R + ++ + + Q+ E P R PP+E + + +
Sbjct: 826 AQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQ 885
Query: 508 KMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPGQQPSV 567
+ +L +P P P ++R L ++ S +S E+ V P Q+ +V
Sbjct: 886 WPQRSQTLAQLPAEKLP------PKKKRLRLAEMAQSSGESSFESS-VPLSRSPSQESNV 938
Query: 568 RLHRGHRNMGVVKNSSLKHRGPA-------------LQGLENGLPTVREKTRAGSKKC-R 613
L R+ ++ K P+ + + + P RE R+ S++
Sbjct: 939 SLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPN 998
Query: 614 FPDDLDTNKKLKKASSKGRKSGGGPEAGVPGRPAGGGHRAGSRAHGHGREAVVAKPKHKR 673
+ K+ G S GP A P P A VA P+ ++
Sbjct: 999 VSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAP----------------PARVAPPERRK 1042
Query: 674 TDYRRWKSSAEISYEEALRRARRGRRENVGLYPAPVPLPYASPYAYVASDSEYSAECES 732
R ++S E L A +GR+E + P P +S + +S S+ S+ S
Sbjct: 1043 CFLVR-QASLSRPPESELEVAPKGRQE------SEEPQPSSSKPSAKSSLSQISSAATS 1094
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 38.9 bits (89), Expect = 0.020
Identities = 55/231 (23%), Positives = 88/231 (38%), Gaps = 23/231 (9%)
Query: 296 DRLGNHASD--ICGGSELDAVKTDSSLPSPSSLW---SASHPSSSKKMDGYILSLVQK-- 348
D G+ A + GG+ D ++SS P P + + SAS S+ ++ S K
Sbjct: 195 DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSP 254
Query: 349 -KTHPVRTNKPRTSVNADPTKGLLRNGSVCVRAPGGVS------QGN----SVNLKNSKQ 397
++ VR PR S P+ L + P G QG S +L SK+
Sbjct: 255 LQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKK 314
Query: 398 ACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRVPLPEGCPSGAASDLQSKHLPKTAK 457
+ P G P T+ ++ + A +KR + +G D + K T K
Sbjct: 315 S--PVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENG--KDKEQKQT-NTDK 369
Query: 458 PASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKVVQPLKK 508
+E S G G+ +S + + E P RG P+ K+ +K
Sbjct: 370 EKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEK 420
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 38.9 bits (89), Expect = 0.020
Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 5/127 (3%)
Query: 423 SKAEQAESKRVPLPEGCPSGAASDLQSKHLP----KTAKPASQEHARCSAIGTGESPKES 478
S++ +R P P PS + P + ++ + R SA +G S S
Sbjct: 304 SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSS 363
Query: 479 AQLSGASPKESPSRGPAPPQENKVVQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPAL 538
+ S + PK+ P R +PP++ + + P ++ + PPATPP + P ++
Sbjct: 364 SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRH-RPSPPATPPPKTRHSPTPQQSNR 422
Query: 539 DFKSEGS 545
KS S
Sbjct: 423 TRKSRVS 429
Score = 30.4 bits (67), Expect = 7.1
Identities = 45/227 (19%), Positives = 82/227 (36%), Gaps = 16/227 (7%)
Query: 390 VNLKNSKQACLPSGGIPSLNNGTFSPPKQWSKESKAEQAESKRV------PLPEGCPSGA 443
V + A L S ++ + SPPK+ K + + +++R+ P PS
Sbjct: 345 VRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPP 404
Query: 444 ASDL-QSKHLPKTAKPASQEHARCSAIGTGESPKESAQLSGASPKESPSRGPAPPQENKV 502
A+ +++H P + +R S + G + + + G +ESPS P P KV
Sbjct: 405 ATPPPKTRHSPTPQQSNRTRKSRVS-VSPGRTSGKVTKHKGTEKRESPSPAPKP---RKV 460
Query: 503 VQPLKKMSQKNSLQGVPPATPPLLSTAFPVEERPALDFKSEGSSQSLEEAHLVKAQFIPG 562
++S+ +G A + + GSS S E+ ++ G
Sbjct: 461 -----ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNG 515
Query: 563 QQPSVRLHRGHRNMGVVKNSSLKHRGPALQGLENGLPTVREKTRAGS 609
+ R H R+ K P + + P + R+ S
Sbjct: 516 EVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS 562
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,932,095
Number of Sequences: 37866
Number of extensions: 1979919
Number of successful extensions: 10811
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 411
Number of HSP's that attempted gapping in prelim test: 9742
Number of HSP's gapped (non-prelim): 1409
length of query: 836
length of database: 18,247,518
effective HSP length: 111
effective length of query: 725
effective length of database: 14,044,392
effective search space: 10182184200
effective search space used: 10182184200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.