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Search of human proteins with 239787151
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239787151 filensin isoform 2 [Homo sapiens]
(540 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239787151 filensin isoform 2 [Homo sapiens] 1055 0.0
gi|4502399 filensin isoform 1 [Homo sapiens] 1053 0.0
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 76 7e-14
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 63 8e-10
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens] 61 2e-09
gi|55956899 keratin 9 [Homo sapiens] 52 1e-06
gi|24308420 KLRAQ motif containing 1 isoform 2 [Homo sapiens] 52 2e-06
gi|208431754 KLRAQ motif containing 1 isoform 1 [Homo sapiens] 52 2e-06
gi|22748757 truncated type I keratin KA21 [Homo sapiens] 51 2e-06
gi|27894337 keratin 20 [Homo sapiens] 51 3e-06
gi|208431757 KLRAQ motif containing 1 isoform 3 [Homo sapiens] 50 4e-06
gi|196115290 glial fibrillary acidic protein isoform 2 [Homo sap... 50 7e-06
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 50 7e-06
gi|109255249 keratin 4 [Homo sapiens] 50 7e-06
gi|239787821 syncoilin, intermediate filament 1 isoform 2 [Homo ... 49 9e-06
gi|21735548 centrosomal protein 2 [Homo sapiens] 49 9e-06
gi|14917117 keratin 33A [Homo sapiens] 49 2e-05
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 49 2e-05
gi|62414289 vimentin [Homo sapiens] 48 3e-05
gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens] 48 3e-05
gi|114431246 keratin 25D [Homo sapiens] 47 3e-05
gi|14249342 internexin neuronal intermediate filament protein, a... 47 3e-05
gi|155969697 keratin 6C [Homo sapiens] 47 4e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 47 4e-05
gi|194018511 keratin 77 [Homo sapiens] 47 6e-05
gi|14917119 keratin 34 [Homo sapiens] 47 6e-05
gi|10337581 type I hair keratin 3B [Homo sapiens] 47 6e-05
gi|5031839 keratin 6A [Homo sapiens] 46 8e-05
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 46 1e-04
gi|119703753 keratin 6B [Homo sapiens] 46 1e-04
>gi|239787151 filensin isoform 2 [Homo sapiens]
Length = 540
Score = 1055 bits (2727), Expect = 0.0
Identities = 540/540 (100%), Positives = 540/540 (100%)
Query: 1 MYENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQT 60
MYENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQT
Sbjct: 1 MYENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQT 60
Query: 61 YISILQQIIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQ 120
YISILQQIIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQ
Sbjct: 61 YISILQQIIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQ 120
Query: 121 TTTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNE 180
TTTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNE
Sbjct: 121 TTTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNE 180
Query: 181 LDRYHRIIEIEGNRLTSAFIETPIPLFTQSHGVSLSTGSGGKDLTRALQDITAAKPRQKA 240
LDRYHRIIEIEGNRLTSAFIETPIPLFTQSHGVSLSTGSGGKDLTRALQDITAAKPRQKA
Sbjct: 181 LDRYHRIIEIEGNRLTSAFIETPIPLFTQSHGVSLSTGSGGKDLTRALQDITAAKPRQKA 240
Query: 241 LPKNVPRRKEIITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESESKEVSPLTQE 300
LPKNVPRRKEIITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESESKEVSPLTQE
Sbjct: 241 LPKNVPRRKEIITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESESKEVSPLTQE 300
Query: 301 GAPEDVPDGGQISKGFGKLYRKVKEKVRSPKEPETPTELYTKERHVLVTGDANYVDPRFY 360
GAPEDVPDGGQISKGFGKLYRKVKEKVRSPKEPETPTELYTKERHVLVTGDANYVDPRFY
Sbjct: 301 GAPEDVPDGGQISKGFGKLYRKVKEKVRSPKEPETPTELYTKERHVLVTGDANYVDPRFY 360
Query: 361 VSSITAKGGVAVSVAEDSVLYDGQVEPSPESPKPPLENGQVGLQEKEDGQPIDQQPIDKE 420
VSSITAKGGVAVSVAEDSVLYDGQVEPSPESPKPPLENGQVGLQEKEDGQPIDQQPIDKE
Sbjct: 361 VSSITAKGGVAVSVAEDSVLYDGQVEPSPESPKPPLENGQVGLQEKEDGQPIDQQPIDKE 420
Query: 421 IEPDGAELEGPEEKREGEERDEESRRPCAMVTPGAEEPSIPEPPKPAADQDGAEVLGTRS 480
IEPDGAELEGPEEKREGEERDEESRRPCAMVTPGAEEPSIPEPPKPAADQDGAEVLGTRS
Sbjct: 421 IEPDGAELEGPEEKREGEERDEESRRPCAMVTPGAEEPSIPEPPKPAADQDGAEVLGTRS 480
Query: 481 RSLPEKGPPKALAYKTVEVVESIEKISTESIQTYEETAVIVETMIGKTKSDKKKSGEKSS 540
RSLPEKGPPKALAYKTVEVVESIEKISTESIQTYEETAVIVETMIGKTKSDKKKSGEKSS
Sbjct: 481 RSLPEKGPPKALAYKTVEVVESIEKISTESIQTYEETAVIVETMIGKTKSDKKKSGEKSS 540
>gi|4502399 filensin isoform 1 [Homo sapiens]
Length = 665
Score = 1053 bits (2722), Expect = 0.0
Identities = 539/539 (100%), Positives = 539/539 (100%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 61
YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY
Sbjct: 127 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 186
Query: 62 ISILQQIIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQT 121
ISILQQIIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQT
Sbjct: 187 ISILQQIIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQT 246
Query: 122 TTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNEL 181
TTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNEL
Sbjct: 247 TTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNEL 306
Query: 182 DRYHRIIEIEGNRLTSAFIETPIPLFTQSHGVSLSTGSGGKDLTRALQDITAAKPRQKAL 241
DRYHRIIEIEGNRLTSAFIETPIPLFTQSHGVSLSTGSGGKDLTRALQDITAAKPRQKAL
Sbjct: 307 DRYHRIIEIEGNRLTSAFIETPIPLFTQSHGVSLSTGSGGKDLTRALQDITAAKPRQKAL 366
Query: 242 PKNVPRRKEIITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESESKEVSPLTQEG 301
PKNVPRRKEIITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESESKEVSPLTQEG
Sbjct: 367 PKNVPRRKEIITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESESKEVSPLTQEG 426
Query: 302 APEDVPDGGQISKGFGKLYRKVKEKVRSPKEPETPTELYTKERHVLVTGDANYVDPRFYV 361
APEDVPDGGQISKGFGKLYRKVKEKVRSPKEPETPTELYTKERHVLVTGDANYVDPRFYV
Sbjct: 427 APEDVPDGGQISKGFGKLYRKVKEKVRSPKEPETPTELYTKERHVLVTGDANYVDPRFYV 486
Query: 362 SSITAKGGVAVSVAEDSVLYDGQVEPSPESPKPPLENGQVGLQEKEDGQPIDQQPIDKEI 421
SSITAKGGVAVSVAEDSVLYDGQVEPSPESPKPPLENGQVGLQEKEDGQPIDQQPIDKEI
Sbjct: 487 SSITAKGGVAVSVAEDSVLYDGQVEPSPESPKPPLENGQVGLQEKEDGQPIDQQPIDKEI 546
Query: 422 EPDGAELEGPEEKREGEERDEESRRPCAMVTPGAEEPSIPEPPKPAADQDGAEVLGTRSR 481
EPDGAELEGPEEKREGEERDEESRRPCAMVTPGAEEPSIPEPPKPAADQDGAEVLGTRSR
Sbjct: 547 EPDGAELEGPEEKREGEERDEESRRPCAMVTPGAEEPSIPEPPKPAADQDGAEVLGTRSR 606
Query: 482 SLPEKGPPKALAYKTVEVVESIEKISTESIQTYEETAVIVETMIGKTKSDKKKSGEKSS 540
SLPEKGPPKALAYKTVEVVESIEKISTESIQTYEETAVIVETMIGKTKSDKKKSGEKSS
Sbjct: 607 SLPEKGPPKALAYKTVEVVESIEKISTESIQTYEETAVIVETMIGKTKSDKKKSGEKSS 665
Score = 38.1 bits (87), Expect = 0.021
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 3/64 (4%)
Query: 95 ALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQ---LYNEQIETLRK 151
AL Q+E R+ + L+A+R L+ Q T ++A+ Y++E + L E +E L K
Sbjct: 87 ALARQVESNRQRVRDLEAERARLERQGTEAQRALDEFRSKYENECECQLLLKEMLERLNK 146
Query: 152 EIEE 155
E +E
Sbjct: 147 EADE 150
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 76.3 bits (186), Expect = 7e-14
Identities = 115/596 (19%), Positives = 231/596 (38%), Gaps = 67/596 (11%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 61
+E E + + + L K+ +EA L + L + Q LQD+++ + H++ + ++
Sbjct: 189 FEEEARLRDDTEAAIRALRKDIEEASLVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQ 248
Query: 62 I------------------SILQQIIHTTPPASIVTSGMREE-------KLL--TEREVA 94
I + L++I S EE KL E+
Sbjct: 249 IQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKE 308
Query: 95 ALRSQLEEGREVLSHLQAQRVELQAQTTT---LEQAIKSAHECYDDEIQLYNEQIETLRK 151
A+RS EE E LQ++ +EL++ T LE+ + E ++ ++ Y + I+ L
Sbjct: 309 AIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLEN 368
Query: 152 EIEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIETPIPLFTQSH 211
E+ T+ + + + + L + L E+ Y +++E E R ++ PL+T
Sbjct: 369 ELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRP 428
Query: 212 GVSLSTG------------------------SGGKDLTRALQDITAAKPRQKALPKNVPR 247
+++S+ + +D +++ A + A+ +
Sbjct: 429 PITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEK 488
Query: 248 RKEIITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESESKEVSPLTQEGAPED-V 306
++ K++ A E+ K +KEE K E E +E EGA D
Sbjct: 489 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 548
Query: 307 PDGGQISKGFGKLYRKVKEKVRSPKEPETPTELYTKERHVLVTGDANYVDPRFYVSSITA 366
+GG +G + +E+ + E E +E+ V + +
Sbjct: 549 EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVE 608
Query: 367 KGGVAVSVAEDSVLYDGQVEPSPESP-----KPPLENGQVGLQEKEDGQPIDQQPIDKEI 421
K A S S + + P P+SP K P+ V E++ P+ + P++++
Sbjct: 609 KPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPV---EEKGKSPVPKSPVEEKG 665
Query: 422 EPDGAELEGPEEKREGEERDE-ESRRPCAMVTPGAEEPSIPEPPKPAADQDGAEVLGTRS 480
+ ++ E+ + + E + A V G ++ + K A ++ E +
Sbjct: 666 KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKP 725
Query: 481 RSLPEKGPPKALAYKTVEVVESIEKISTESIQTYEETAVIVETMIGKTKSDKKKSG 536
+ +PEK KA + E V + I T+S++ + E E + + +K+K+G
Sbjct: 726 KDVPEK--KKAESPVKEEAVAEVVTI-TKSVKVHLEKETKEEGKPLQQEKEKEKAG 778
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 62.8 bits (151), Expect = 8e-10
Identities = 97/433 (22%), Positives = 165/433 (38%), Gaps = 57/433 (13%)
Query: 95 ALRSQLEEGREVLSHLQAQRVELQAQTTT---LEQAIKSAHECYDDEIQLYNEQIETLRK 151
A+RS EE E LQA+ EL+A +T LE+ + + +I Y E I+ L
Sbjct: 310 AMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDA 369
Query: 152 EIEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIETPIPLFTQSH 211
E+ T+ + + + L + L E+ Y +++E E R+ PIP
Sbjct: 370 ELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFG----PIPF----- 420
Query: 212 GVSLSTGSGGKDLTRALQDITAAKPRQKALPKNVPRRKEIITKDKTNGALEDAPLKGLED 271
L L I + K K+ + K + +K +E+ E+
Sbjct: 421 -----------SLPEGLPKIPSVSTHIKV--KSEEKIKVVEKSEKETVIVEEQ----TEE 463
Query: 272 TKLVQVVLKEESESKFESESKEVSPLTQEGAPEDVPDGG----------QISKGFGKLYR 321
T++ + V +EE + E E KE +EG E+ +GG + + +
Sbjct: 464 TQVTEEVTEEEEKEAKEEEGKE-----EEGGEEEEAEGGEEETKSPPAEEAASPEKEAKS 518
Query: 322 KVKEKVRSP--------KEPETPTELYTKERHVLVTGDANYVDPRF-YVSSITAKGGVAV 372
VKE+ +SP +E ++P E+ + E+ + P AK V
Sbjct: 519 PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV 578
Query: 373 SVAEDSVLYDGQVEPSPESPKPPLENGQVGLQEKEDGQPIDQQPIDKEIEPDGAELEGPE 432
E + + SP K P E + ++E+ + P+ KE AE++ PE
Sbjct: 579 KSPEKAKSPAKEEAKSPAEAKSP-EKAKSPVKEEAKSPAEAKSPV-KEEAKSPAEVKSPE 636
Query: 433 EKREGEERDEESRRPCAMVTPGAEEPSIPEPPKPAADQDGAEVLGTRSRSLPEKGPPKAL 492
+ + + EE++ P +P EE PE K + +S E P+
Sbjct: 637 KAKSPTK--EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 493 AYKTVEVVESIEK 505
E +S EK
Sbjct: 695 KSPVKEEAKSPEK 707
Score = 41.2 bits (95), Expect = 0.002
Identities = 69/322 (21%), Positives = 123/322 (38%), Gaps = 32/322 (9%)
Query: 234 AKPRQKALPKNVPRRKEIITKDKTNGALEDAPLKGLEDT-KLVQVVLKEESESKFESESK 292
AK K K+ + K + ++ + +P+K T + + +KEE++S +++S
Sbjct: 694 AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP 753
Query: 293 EVSPLTQEGAPE-DVPDGGQISKGFGKLYRK----VKEKVRSPKEPETPTELYTKERHVL 347
E + +PE P + K K VKE+V+SP++ ++P +
Sbjct: 754 EKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK--------- 804
Query: 348 VTGDANYVDPRFYVSSITAKGGVAVSVAEDSVLYDGQVEPSPESPKPPLENGQVGLQEKE 407
D + I K V V E+ + +V+ P+ + +EK+
Sbjct: 805 -------EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKK 857
Query: 408 DGQ----PIDQQPIDKEIEPDGAELEGPEEKREGEERDEESRRPCAMVTPGAEEPSIPEP 463
D + P + P K E +E P+E + E + EE+ + TP E P+ E
Sbjct: 858 DSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV-EAKKEEAEDKKKVPTPEKEAPAKVEV 916
Query: 464 PKPAADQDGAEVLGTRSRSLPEKGPPKALAYKTV-----EVVESIEKISTESIQTYEETA 518
+ A ++ EV K P K K + E K E +T +
Sbjct: 917 KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAK 976
Query: 519 VIVETMIGKTKSDKKKSGEKSS 540
+T+ + K + EKSS
Sbjct: 977 EDDKTLSKEPSKPKAEKAEKSS 998
Score = 40.8 bits (94), Expect = 0.003
Identities = 69/314 (21%), Positives = 127/314 (40%), Gaps = 31/314 (9%)
Query: 234 AKPRQKALPKNVPRRKEIITKDKTNGALEDAPLKG-LEDTKLVQVVLKEESESKFESESK 292
AK +K K+ + K + + + +P+K + + + +KEE++S K
Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP----EK 707
Query: 293 EVSPLTQEG-APEDVPDG-GQISKGFGKLYRKVKEKVRSPKEPETPTELYTKERHVLVTG 350
SP+ +E +PE + +K K VKE+ +SP++ ++P + T +
Sbjct: 708 AKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAK 767
Query: 351 DANYVDPRFYVSSITAKGGVAVSVAEDSVLYDGQVEPSPESPKPPLENGQVGLQEKEDGQ 410
+ R K A S ++ V SPE K PL KED +
Sbjct: 768 TPAKEEARSPADKFPEK---AKSPVKEEV-------KSPEKAKSPL---------KEDAK 808
Query: 411 -PIDQQPIDKEIEPDGAELEGPEE--KREGEERDEESRRPCAMVTPGAEEPSIPEPPKPA 467
P + P +E++ E E P+E +E ++ EE + P T ++ E PK
Sbjct: 809 APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE 868
Query: 468 ADQDGAEVLGTRSRSLPEKGPPKALAYKTVE--VVESIEKISTESIQTYEETAVIVETMI 525
A + E + P++ +A + + V + EK + ++ E+ +T +
Sbjct: 869 APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEV 928
Query: 526 GKTKSDKKKSGEKS 539
K + D K+ E S
Sbjct: 929 AKKEPDDAKAKEPS 942
>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
Length = 543
Score = 61.2 bits (147), Expect = 2e-09
Identities = 80/345 (23%), Positives = 142/345 (41%), Gaps = 36/345 (10%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 61
YE E + + L K ADEA L L+ L D+IS K H++ + E+Q
Sbjct: 178 YEEEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEISFLKKVHEEEIAELQAQ 237
Query: 62 ISILQQIIH---TTPPASIVTSGMRE--EKL------------------LTE---REVAA 95
I Q + T P S +R EKL LTE + A
Sbjct: 238 IQYAQISVEMDVTKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDA 297
Query: 96 LRSQLEEGREVLSHLQAQRVELQA---QTTTLEQAIKSAHECYDDEIQLYNEQIETLRKE 152
+R+ +E E L+A+ +E++A LE+ ++ + + +I + I L E
Sbjct: 298 VRAAKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENE 357
Query: 153 IEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIETPIPLFTQSHG 212
+ T+ + + + + L + L E+ Y +++E E RL+ + + ++QS
Sbjct: 358 LRTTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQ 417
Query: 213 VSLSTGSGGKDLTRALQDITAAKPR--QKALPKNVPRRKEIITKDKTNGALEDAPLKGLE 270
V + GG + L T + P + + +E I K A ++ P +G
Sbjct: 418 VFGRSAYGGLQTSSYLMS-TRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEA 476
Query: 271 DTKLVQVVLKEESESKFESESKEVSPLTQEGAPEDVPDGGQISKG 315
+ + KEE+E + +E +E + E A E+ +GG+ +G
Sbjct: 477 EEEEKD---KEEAEEEEAAEEEEAAKEESEEAKEE-EEGGEGEEG 517
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 52.0 bits (123), Expect = 1e-06
Identities = 43/207 (20%), Positives = 91/207 (43%), Gaps = 36/207 (17%)
Query: 12 LKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHT 71
L+++L+ L E + L+++ + LQ+++ A K HK+ + ++ S +
Sbjct: 260 LRQVLDNLTMEKSD-------LEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEIN 312
Query: 72 TPPASIVTSGMREEKLLTEREVAALRSQLEE----------------GREVLSH------ 109
P +T + + + E+ +A R +E G+EV S
Sbjct: 313 VAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQ 372
Query: 110 ----LQAQRVELQAQTT---TLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEK 162
+Q +ELQ+Q + LE++++ Y ++Q+ EQI L +I + + +E
Sbjct: 373 LRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIEC 432
Query: 163 SSYDCRQLAVAQQTLKNELDRYHRIIE 189
+ + L + L+ E++ YH ++E
Sbjct: 433 QNQEYSLLLSIKMRLEKEIETYHNLLE 459
Score = 35.4 bits (80), Expect = 0.13
Identities = 42/160 (26%), Positives = 65/160 (40%), Gaps = 18/160 (11%)
Query: 13 KEMLERLN--KEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIH 70
K++ + LN ++ E L+ R +E Q+ + I+ + + EVQ+ + Q+ H
Sbjct: 317 KDLTKTLNDMRQEYEQLIAKNRKDIENQY-ETQITQIEHEVSSSGQEVQSSAKEVTQLRH 375
Query: 71 TTPPASIVTSGMREEKLLTEREVAALRSQLEEGRE----VLSHLQAQRVELQAQTTTLEQ 126
I +K AAL LE+ + L +Q Q L+AQ T + Q
Sbjct: 376 GVQELEIELQSQLSKK-------AALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQ 428
Query: 127 AIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYD 166
I EC + E L L KEIE +LE D
Sbjct: 429 EI----ECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQED 464
>gi|24308420 KLRAQ motif containing 1 isoform 2 [Homo sapiens]
Length = 769
Score = 51.6 bits (122), Expect = 2e-06
Identities = 56/227 (24%), Positives = 97/227 (42%), Gaps = 28/227 (12%)
Query: 9 QLLLKEM-LERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQ 67
QL +K+ L +L +E D NL+L + LQD+++ ++ R KKN ++ + Q+
Sbjct: 44 QLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQE 103
Query: 68 IIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQA 127
S+ + +K + E E L Q E E H++A EL+++ TLE
Sbjct: 104 ------QKSVFDEDL--QKKIEENE--RLHIQFFEADEQHKHVEA---ELRSRLATLETE 150
Query: 128 IKSAHECYDDEIQLYNEQIETLRKE---IEETERVLEKSSYDCR--------QLAVAQQT 176
D + Y E IE L+ + +E + LEK + +CR QL +
Sbjct: 151 AAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHED 210
Query: 177 LKNELDRYHRIIEIE---GNRLTSAFIETPIPLFTQSHGVSLSTGSG 220
L L+ II + + S + +PL + H + + +G
Sbjct: 211 LSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAG 257
>gi|208431754 KLRAQ motif containing 1 isoform 1 [Homo sapiens]
Length = 780
Score = 51.6 bits (122), Expect = 2e-06
Identities = 56/227 (24%), Positives = 97/227 (42%), Gaps = 28/227 (12%)
Query: 9 QLLLKEM-LERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQ 67
QL +K+ L +L +E D NL+L + LQD+++ ++ R KKN ++ + Q+
Sbjct: 44 QLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQE 103
Query: 68 IIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQA 127
S+ + +K + E E L Q E E H++A EL+++ TLE
Sbjct: 104 ------QKSVFDEDL--QKKIEENE--RLHIQFFEADEQHKHVEA---ELRSRLATLETE 150
Query: 128 IKSAHECYDDEIQLYNEQIETLRKE---IEETERVLEKSSYDCR--------QLAVAQQT 176
D + Y E IE L+ + +E + LEK + +CR QL +
Sbjct: 151 AAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHED 210
Query: 177 LKNELDRYHRIIEIE---GNRLTSAFIETPIPLFTQSHGVSLSTGSG 220
L L+ II + + S + +PL + H + + +G
Sbjct: 211 LSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAG 257
>gi|22748757 truncated type I keratin KA21 [Homo sapiens]
Length = 295
Score = 51.2 bits (121), Expect = 2e-06
Identities = 29/102 (28%), Positives = 51/102 (50%)
Query: 90 EREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNEQIETL 149
E + A +++L+E R HLQ + L A LE ++ ++ + Y ++Q IE L
Sbjct: 45 EEALKAAQAELKEARRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGL 104
Query: 150 RKEIEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIE 191
KE++E R +EK + L + L+ E+ Y ++E E
Sbjct: 105 EKELQEVRRGIEKQLQEHEMLLNTKMRLEQEIATYRHLLEKE 146
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 50.8 bits (120), Expect = 3e-06
Identities = 45/230 (19%), Positives = 93/230 (40%), Gaps = 29/230 (12%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 61
YE E +L ++ L+ LNK D+ LH L+++ + L D++ K H++ + + +
Sbjct: 159 YETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKH 218
Query: 62 ISILQQIIHTTPPA---SIVTSGMR------------EEKLLTEREVAALRSQLEEGREV 106
+ + P ++ + MR E K ER+ A L+ Q+ E
Sbjct: 219 LGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEE 278
Query: 107 LSHLQAQRVELQ--------------AQTTTLEQAIKSAHECYDDEIQLYNEQIETLRKE 152
L + Q EL+ + +LE ++ Y ++ + +L +
Sbjct: 279 LKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQ 338
Query: 153 IEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIET 202
+ + +E+ + + L + L+ E+ Y R++E E + T + T
Sbjct: 339 LMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVKTTEYQLST 388
>gi|208431757 KLRAQ motif containing 1 isoform 3 [Homo sapiens]
Length = 734
Score = 50.4 bits (119), Expect = 4e-06
Identities = 53/221 (23%), Positives = 93/221 (42%), Gaps = 27/221 (12%)
Query: 14 EMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHTTP 73
+ L +L +E D NL+L + LQD+++ ++ R KKN ++ + Q+
Sbjct: 4 QSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQE------ 57
Query: 74 PASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHE 133
S+ + +K + E E L Q E E H++A EL+++ TLE
Sbjct: 58 QKSVFDEDL--QKKIEENE--RLHIQFFEADEQHKHVEA---ELRSRLATLETEAAQHQA 110
Query: 134 CYDDEIQLYNEQIETLRKE---IEETERVLEKSSYDCR--------QLAVAQQTLKNELD 182
D + Y E IE L+ + +E + LEK + +CR QL + L L+
Sbjct: 111 VVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLE 170
Query: 183 RYHRIIEIE---GNRLTSAFIETPIPLFTQSHGVSLSTGSG 220
II + + S + +PL + H + + +G
Sbjct: 171 ESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAG 211
>gi|196115290 glial fibrillary acidic protein isoform 2 [Homo
sapiens]
Length = 431
Score = 49.7 bits (117), Expect = 7e-06
Identities = 57/264 (21%), Positives = 109/264 (41%), Gaps = 42/264 (15%)
Query: 3 ENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYI 62
++E +L + L +EADEA L L L+ + + L+++I + H++ + E+Q +
Sbjct: 156 QDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQL 215
Query: 63 SILQQIIHTTPPASIVTSGMREEKLLTE--------------------------REVAAL 96
+ Q + +T+ ++E + E R L
Sbjct: 216 ARQQVHVELDVAKPDLTAALKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAELL 275
Query: 97 RSQLEEGREVLSHLQAQRVELQAQTTT---LEQAIKSAHECYDDEIQLYNEQIETLRKEI 153
R E + LQ+ +L++ T LE+ ++ E + E Y E + L +E
Sbjct: 276 RQAKHEANDYRRQLQSLTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEEG 335
Query: 154 EETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIETPIPLFTQSH-- 211
+ + + + + + L + L E+ Y +++E E NR+T IP+ T S+
Sbjct: 336 QSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRIT-------IPVQTFSNLQ 388
Query: 212 ---GVSLSTGSGGKDLTRALQDIT 232
G S G K +TR L+ +T
Sbjct: 389 IRGGKSTKDGENHK-VTRYLKSLT 411
>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
Length = 1217
Score = 49.7 bits (117), Expect = 7e-06
Identities = 48/198 (24%), Positives = 91/198 (45%), Gaps = 26/198 (13%)
Query: 12 LKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHT 71
+KE E+L+ E E + +L+L+A+ LQD+++ ++ K+ L E Q + +++
Sbjct: 284 MKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEE---- 339
Query: 72 TPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQA------QTTTLE 125
++E TE + +++ + E G L+ +R +L A Q T+ E
Sbjct: 340 ----------KQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKE 389
Query: 126 QA---IKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLK---N 179
+ IK + D I QI + K++E+TE EK+ +L +K
Sbjct: 390 ERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKEKNLEQYNKLDQDLNEVKARVE 449
Query: 180 ELDRYHRIIEIEGNRLTS 197
ELDR + ++ + + L S
Sbjct: 450 ELDRKYYEVKNKKDELQS 467
Score = 35.0 bits (79), Expect = 0.17
Identities = 43/188 (22%), Positives = 78/188 (41%), Gaps = 11/188 (5%)
Query: 83 REEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLY 142
+EE + +E R ++ E +L +++ + L+ + L Q K E +Y
Sbjct: 172 KEESISLMKETEGKREKINE---LLKYIEERLHTLEEEKEELAQYQKWDKMRRALEYTIY 228
Query: 143 NEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIET 202
N+++ R +++E E S RQL AQQ +++++ R + ++++ E
Sbjct: 229 NQELNETRAKLDELSAKRETSGEKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEK 288
Query: 203 PIPLFTQSHGVSLST--GSGGKDLTRAL-----QDITAAKPRQKALPKNVPRRKEII-TK 254
+ + T KDL L Q K RQK L K ++KE+ T+
Sbjct: 289 EQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETE 348
Query: 255 DKTNGALE 262
K N E
Sbjct: 349 PKFNSVKE 356
Score = 32.3 bits (72), Expect = 1.1
Identities = 37/175 (21%), Positives = 74/175 (42%), Gaps = 31/175 (17%)
Query: 3 ENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKD------------- 49
E E + L+ +ER+N E D+ L N Q+E Q Q A++D
Sbjct: 691 ELEAKLNENLRRNIERINNEIDQ--LMNQMQQIETQ--QRKFKASRDSILSEMKMLKEKR 746
Query: 50 -RHKKNLLEVQTYISILQQIIHTTPP------ASIVTSGMREEKLLTEREVAALRSQLEE 102
+ +K + Q + L+ +H A + T + + L ++ V AL ++ +
Sbjct: 747 QQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDALNDEIRQ 806
Query: 103 GREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETE 157
++ L +R++L+ T +E + ++ ++ +Q+E E+ ETE
Sbjct: 807 LQQENRQLLNERIKLEGIITRVETYL-------NENLRKRLDQVEQELNELRETE 854
>gi|109255249 keratin 4 [Homo sapiens]
Length = 594
Score = 49.7 bits (117), Expect = 7e-06
Identities = 46/195 (23%), Positives = 85/195 (43%), Gaps = 21/195 (10%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 61
YE E + + L K+ D A L+ + L+ + L D+I+ K + L ++QT+
Sbjct: 301 YEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTH 360
Query: 62 ISILQQIIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQT 121
+S S+V S L + +A +R+Q EE Q + E +A
Sbjct: 361 VS----------DTSVVLSMDNNRNLDLDSIIAEVRAQYEE------IAQRSKAEAEALY 404
Query: 122 TTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAV----AQQTL 177
T Q ++ + + + D ++ +I L + I+ +E C+ L V A+Q
Sbjct: 405 QTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRG 464
Query: 178 KNEL-DRYHRIIEIE 191
+N L D + + +E+E
Sbjct: 465 ENALKDAHSKRVELE 479
>gi|239787821 syncoilin, intermediate filament 1 isoform 2 [Homo
sapiens]
Length = 476
Score = 49.3 bits (116), Expect = 9e-06
Identities = 42/181 (23%), Positives = 79/181 (43%), Gaps = 4/181 (2%)
Query: 12 LKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHT 71
L E L +L ++A + LR QLEA Q D ++ + + Q +
Sbjct: 284 LSEELAQL-RDAYQKQKEQLRQQLEAPPSQRDGHFLQESRRLSAQFENLMAESRQDLEEE 342
Query: 72 TPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSA 131
P + + E K + + +++++E +E L LQA+ +L+ Q LE I
Sbjct: 343 YEPQFL---RLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALV 399
Query: 132 HECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIE 191
+ D+E+Q Y EQ+E + + + ++ +++ + +L EL Y +EI
Sbjct: 400 RQKRDEEVQQYREQLEEMEERQRQLRNGVQLQQQKNKEMEQLRLSLAEELSTYKGCLEIY 459
Query: 192 G 192
G
Sbjct: 460 G 460
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 49.3 bits (116), Expect = 9e-06
Identities = 66/309 (21%), Positives = 137/309 (44%), Gaps = 35/309 (11%)
Query: 12 LKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHT 71
L++ L++L E D + LQ E D +S ++ +K E++ + +L+Q
Sbjct: 433 LRQRLQKLTGERDTLAGQTVDLQGEV----DSLSKERELLQKAREELRQQLEVLEQEAWR 488
Query: 72 TPPASIV-------TSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTL 124
++ G +EE+ + E+ + E +E+L L+A++ E ++ TL
Sbjct: 489 LRRVNVELQLQGDSAQGQKEEQ---QEELHLAVRERERLQEMLMGLEAKQSESLSELITL 545
Query: 125 EQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNEL-DR 183
+A++S+H + E LR+E E L ++ +L+ ++ TLK E+ D
Sbjct: 546 REALESSHL-----------EGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADL 594
Query: 184 YHRIIEI----EGNRLTSAFIETPIPLFTQSHGVSLSTGSGGKDLTRALQ-DITAAKPRQ 238
+++ E L + + + + S + ALQ D+ A+ R+
Sbjct: 595 RAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRR 654
Query: 239 KALPKNVPRRKEIITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESE--SKEVSP 296
+AL + + + K + GA A L+ +++ K + + K+ SES+ + E + ++
Sbjct: 655 EALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEK--EEIQKKLSESRHQQEAATTQLEQ 712
Query: 297 LTQEGAPED 305
L QE ++
Sbjct: 713 LHQEAKRQE 721
Score = 44.7 bits (104), Expect = 2e-04
Identities = 62/295 (21%), Positives = 131/295 (44%), Gaps = 41/295 (13%)
Query: 7 ECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQ 66
E ++ LKE ++ EA +A R Q E+ Q + K+R +LLE T + +
Sbjct: 886 ELEMRLKE--QQTEMEAIQAQREEERTQAESALCQMQLETEKER--VSLLE--TLLQTQK 939
Query: 67 QIIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQR----VELQAQTT 122
++ + + M+ +KL + L++QL+E + L Q LQ +++
Sbjct: 940 ELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESS 999
Query: 123 TLEQAIKSAHECYDDEIQLYNEQIETLRKEI---EETERVLEKSSYDCRQLAVAQQTLK- 178
+L Q D++ L +Q+E L+ ++ ++++R++E+ Q+ L+
Sbjct: 1000 SLLQ----------DKMDL-QKQVEDLKSQLVAQDDSQRLVEQE---------VQEKLRE 1039
Query: 179 -NELDRYHRIIEIEGNRLTSAFIETPIPLFTQSHGVSLSTGSGGKDLTRALQDITAAKPR 237
E +R + +E E LT + +E L S+ ++L+ QD+ A+
Sbjct: 1040 TQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQ----QELSALRQDMQEAQGE 1095
Query: 238 QKALPKNVPRRKEIITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESESK 292
QK L + ++ + + + + ++A L LE+ + + ++ S + E+K
Sbjct: 1096 QKELSAQMELLRQEVKEKEADFLAQEAQL--LEELEASHITEQQLRASLWAQEAK 1148
Score = 40.4 bits (93), Expect = 0.004
Identities = 49/192 (25%), Positives = 83/192 (43%), Gaps = 19/192 (9%)
Query: 3 ENECECQLL-LKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 61
+N E +L+ L E + L A L + Q E + LQ AAK+ + +Q
Sbjct: 1308 QNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQ----AAKENLTAQVEHLQA- 1362
Query: 62 ISILQQIIHTTPPASIVTSGMREEKLLTEREVAALRSQ-LEEGREVLSHLQAQRVELQAQ 120
++ AS +G+ EE L T R L+++ +E RE LQ Q AQ
Sbjct: 1363 -----AVVEARAQAS--AAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQ 1415
Query: 121 TTTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNE 180
L++ + + + E++ETLR +I+E E+ E L++ + E
Sbjct: 1416 GKALQENLALLTQTLAER----EEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQE 1471
Query: 181 LD-RYHRIIEIE 191
+D + +I E+E
Sbjct: 1472 VDLQQEQIQELE 1483
Score = 39.7 bits (91), Expect = 0.007
Identities = 71/307 (23%), Positives = 135/307 (43%), Gaps = 39/307 (12%)
Query: 12 LKEMLERL-NKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIH 70
++++ ERL + EA+++ +H L+ Q Q+ +K K+N LE S L ++
Sbjct: 1266 VQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLE-----SELMELHE 1320
Query: 71 TTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLS----HLQAQRVELQAQTTT--- 123
T AS+ + R E L E R L+ +E L+ HLQA VE +AQ +
Sbjct: 1321 TM--ASLQSRLRRAE--LQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGI 1376
Query: 124 LEQAIKSAHECYDDEIQLYNEQIETLRKEI----EETERVLEKSSYDCRQLAVAQQTLKN 179
LE+ +++A ++L NE++E+ R+ E+ E + + LA+ QTL
Sbjct: 1377 LEEDLRTARSA----LKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAE 1432
Query: 180 ELDRYH----RIIEIEGNR-LTSAFIE-TPIPLFTQSHGVSLSTGSGGKDLTRALQDITA 233
+ +I E+E R + A +E + L ++ V L +Q++
Sbjct: 1433 REEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQ--------QEQIQELEK 1484
Query: 234 AKPRQKALPKNVPRRKEIITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESESKE 293
+ + LP V R++ +T + + + + Q++ E+ + ES+ +
Sbjct: 1485 CRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQ 1544
Query: 294 VSPLTQE 300
V L ++
Sbjct: 1545 VQDLKKQ 1551
Score = 39.7 bits (91), Expect = 0.007
Identities = 48/218 (22%), Positives = 87/218 (39%), Gaps = 27/218 (12%)
Query: 99 QLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETER 158
+LE+ R VL HL E + + T + I+ + + + + Q+ E+E+ ++
Sbjct: 1481 ELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQL----LELEKKDQ 1536
Query: 159 VLEKSS---YDCRQLAVAQQTLKNELDRYHR--------IIEIEGNRLTSAFIETPIPLF 207
++E D ++ V + L EL+ H I E+EG R T T + L
Sbjct: 1537 MIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLD 1596
Query: 208 TQSHGVSLSTGSG--------GKDLTRALQDITAAKPRQKALPKNVPRRKEIITKDKTNG 259
+ L S L R LQ+ Q+ + + R+KE +T+D
Sbjct: 1597 LEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERR 1656
Query: 260 ----ALEDAPLKGLEDTKLVQVVLKEESESKFESESKE 293
L+ ++ LED + Q + EE + + +E
Sbjct: 1657 DQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRE 1694
Score = 39.3 bits (90), Expect = 0.009
Identities = 42/201 (20%), Positives = 87/201 (43%), Gaps = 9/201 (4%)
Query: 13 KEMLERLNKEAD---EALLHNL-RLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQI 68
+E + L K+ + L H L L+ + Q ++ +D KK L+ ++ L++
Sbjct: 1507 REQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDL-KKQLVTLECLALELEEN 1565
Query: 69 IHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAI 128
H + + ++ + L LEE + L +Q +L++ +T L + +
Sbjct: 1566 HHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLAREL 1625
Query: 129 KSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRII 188
+ D E++ EQIE L+++ E + LE+ + Q L+++ R +I+
Sbjct: 1626 QER----DQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKIL 1681
Query: 189 EIEGNRLTSAFIETPIPLFTQ 209
E + ++ + E L TQ
Sbjct: 1682 EEDLEQIKLSLRERGRELTTQ 1702
Score = 36.6 bits (83), Expect = 0.060
Identities = 43/176 (24%), Positives = 78/176 (44%), Gaps = 16/176 (9%)
Query: 12 LKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHT 71
L++ E+ + +E + R+Q + L D+ A +K LL +Q + Q H
Sbjct: 1861 LQDHKEQARRLEEELAVEGRRVQALEEVL-GDLRAESREQEKALLALQQQCAEQAQE-HE 1918
Query: 72 TPPASIVTSGMREEKLLTER--EVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIK 129
++ S ++ + +L ER E+ ALR++ + R Q +A+ L++A+
Sbjct: 1919 VETRALQDSWLQAQAVLKERDQELEALRAESQSSRH-------QEEAARARAEALQEALG 1971
Query: 130 SAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDC----RQLAVAQQTLKNEL 181
AH + Q EQ E L + +E + L+ S C RQL A + + E+
Sbjct: 1972 KAHAALQGKEQHLLEQAE-LSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEI 2026
Score = 34.7 bits (78), Expect = 0.23
Identities = 53/255 (20%), Positives = 103/255 (40%), Gaps = 19/255 (7%)
Query: 96 LRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEE 155
L +QL++ E + LQA ++Q + +++ + + + + Q+E L +E +
Sbjct: 664 LEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRH----QQEAATTQLEQLHQEAKR 719
Query: 156 TERVL-----EKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIETPIPLFTQS 210
E VL EK + + A+ + E DR +++G +E+ + Q
Sbjct: 720 QEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQ 779
Query: 211 HGVSLSTGSGGKDLTRALQDITAAKPRQKALPKNVPRRKEIITKDKTNGALE-DAPLKGL 269
+ V T L +Q +T AK + + V K + +++ E DA + L
Sbjct: 780 NSVIEVTKG---QLEVQIQTVTQAK---EVIQGEVRCLKLELDTERSQAEQERDAAARQL 833
Query: 270 EDTKLVQVVLKEESESKFESESKEVSPLTQEGAPEDVPDGGQISKGFGKLYRKVKEKVRS 329
+ E+ ++ E KEV+ L ++ E +++K L R+ E
Sbjct: 834 AQAEQEGKTALEQQKAAHE---KEVNQLREKWEKERSWHQQELAKALESLEREKMELEMR 890
Query: 330 PKEPETPTELYTKER 344
KE +T E +R
Sbjct: 891 LKEQQTEMEAIQAQR 905
Score = 34.7 bits (78), Expect = 0.23
Identities = 50/200 (25%), Positives = 83/200 (41%), Gaps = 38/200 (19%)
Query: 21 KEADEALLHNLR-LQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHTTPPASIVT 79
+EA L +LR +Q E + +Q +S + RH++ Q L+Q+ V
Sbjct: 672 EEAGAELQADLRDIQEEKEEIQKKLS--ESRHQQEAATTQ-----LEQLHQEAKRQEEVL 724
Query: 80 SGMREEKLLTEREVAALRSQL---EEGREVLSH-----------LQAQRVELQAQTTTLE 125
+ +EK RE AAL +L E R+ L+ L++ E Q Q + +E
Sbjct: 725 ARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIE 784
Query: 126 ----------QAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQ 175
Q + A E E++ +++T R + E ++ RQLA A+Q
Sbjct: 785 VTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAE------QERDAAARQLAQAEQ 838
Query: 176 TLKNELDRYHRIIEIEGNRL 195
K L++ E E N+L
Sbjct: 839 EGKTALEQQKAAHEKEVNQL 858
Score = 32.7 bits (73), Expect = 0.86
Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 8/110 (7%)
Query: 90 EREVAALRSQLEEGRE----VLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNEQ 145
E+E+ L+ QL+E RE LQ+Q E Q +Q + E E Q Q
Sbjct: 1777 EQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQEL----EALQQEQQQAQGQ 1832
Query: 146 IETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRL 195
E ++++ + + LE++ ++ Q K + R + +EG R+
Sbjct: 1833 EERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRV 1882
Score = 30.0 bits (66), Expect = 5.6
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 23/114 (20%)
Query: 90 EREVAALRSQLEEGREVLSHLQAQRVE--LQAQTTTLEQAIKSAHECYDDEIQLYNEQIE 147
ERE L +L+E + + +QAQR E QA++ + +++ E + L ++
Sbjct: 881 EREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKE----RVSLLETLLQ 936
Query: 148 TLRKEIEETERVLEKSSYDCR---------------QLAVAQQTLKNELDRYHR 186
T +KE+ + + LE+ D + QL AQ+ LK E R HR
Sbjct: 937 T-QKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELK-EAARQHR 988
Score = 30.0 bits (66), Expect = 5.6
Identities = 28/153 (18%), Positives = 62/153 (40%), Gaps = 10/153 (6%)
Query: 59 QTYISILQQIIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQ 118
Q + + QQ+ + ++ + +R +A +LE ++ Q Q ++
Sbjct: 1778 QEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVK 1837
Query: 119 AQTTTLEQAIKSAHECYDD---EIQLYNEQIETLRKE-------IEETERVLEKSSYDCR 168
+ L+ A++ AH + E+Q + EQ L +E ++ E VL + R
Sbjct: 1838 EKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESR 1897
Query: 169 QLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIE 201
+ A L+ + + E+E L ++++
Sbjct: 1898 EQEKALLALQQQCAEQAQEHEVETRALQDSWLQ 1930
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 48.5 bits (114), Expect = 2e-05
Identities = 44/225 (19%), Positives = 93/225 (41%), Gaps = 29/225 (12%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNL------ 55
YE E + L++ + L + DE L L+ + + L++++ K H++ +
Sbjct: 145 YETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQ 204
Query: 56 ------LEVQTYISI-LQQIIHTTPPA--SIVTSGMREEKLLTEREVAALRSQLEEGREV 106
+EV ++ L Q+++ T ++V + RE + + L Q+ E
Sbjct: 205 LGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQ 264
Query: 107 LSHLQAQRVELQAQTTTLEQAIKSAHEC--------------YDDEIQLYNEQIETLRKE 152
L QA+ +EL+ LE +++ H Y ++ I + +
Sbjct: 265 LQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQ 324
Query: 153 IEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTS 197
+ E LE+ + + + L + L+ E++ Y ++E E +L S
Sbjct: 325 LAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPS 369
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 48.5 bits (114), Expect = 2e-05
Identities = 75/339 (22%), Positives = 137/339 (40%), Gaps = 46/339 (13%)
Query: 7 ECQLLLKEMLE-RLNKEADEALLHNLRLQL--EAQFLQDDISAAKDRHKKNLLEVQTYIS 63
E + L +E+ E R + E +A+L L ++ E ++++ A + RH+K +L V+
Sbjct: 411 EKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYE 470
Query: 64 ILQQIIHTTPPASIVTSGMREEKLLTE-REVAALRSQLEEGREVLSHLQAQRVELQAQTT 122
+ +H +EE+L + RE A +LE ++ + LQAQ +
Sbjct: 471 RELRELHEDKKR-------QEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKG 523
Query: 123 TLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCR-QLAVAQQTLKNEL 181
E+ +K A E + Q E ++ R++ + E+ D R QL AQ+
Sbjct: 524 WFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQE------ 577
Query: 182 DRYHRIIEIEGNRLTSAFIETPIPLFTQSHGVSLSTGSGG-KDLTRALQDITAAKPRQKA 240
E + + T + ++ + + GS KDL R L +K
Sbjct: 578 -------ERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLH------LERKR 624
Query: 241 LPKNVPRRKEIITKDKTNGALEDAPLKGLEDTKLVQV-------------VLKEESESKF 287
K R ++I+T K+ LE+ L + Q +L+E+ S
Sbjct: 625 ADKLQERLQDILTNSKSRSGLEELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAV 684
Query: 288 ESESKEVSPLTQEGAPEDVPDGGQISKGFGKLYRKVKEK 326
+ S SP Q P ++ D ++++ F +L +EK
Sbjct: 685 PARSLSSSPQAQPPRPAELSD-EEVAELFQRLAETQQEK 722
Score = 34.7 bits (78), Expect = 0.23
Identities = 40/193 (20%), Positives = 81/193 (41%), Gaps = 14/193 (7%)
Query: 12 LKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHT 71
++E+ +R + L +LQ E + ++ +D+ + LE + LQ +
Sbjct: 260 IEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQV-- 317
Query: 72 TPPASIVTSGMRE--EKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIK 129
SI ++ +E E LL E ALR+ L ++ + + L+ QTT L ++
Sbjct: 318 ----SIQSADAQEQVEGLLAENN--ALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQ 371
Query: 130 SAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIE 189
Y+D + ++ L++ + R+LE+ +++ ++ L EL + E
Sbjct: 372 QQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQ----LQEIGQEKEQLTQELQEARKSAE 427
Query: 190 IEGNRLTSAFIET 202
L +ET
Sbjct: 428 KRKAMLDELAMET 440
>gi|62414289 vimentin [Homo sapiens]
Length = 466
Score = 47.8 bits (112), Expect = 3e-05
Identities = 48/222 (21%), Positives = 90/222 (40%), Gaps = 34/222 (15%)
Query: 16 LERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHTTPPA 75
L+ ++ D A L L L+ + + LQ++I+ K H++ + E+Q I I
Sbjct: 203 LQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSK 262
Query: 76 SIVTSGMREEKLLTEREVA--------------------------ALRSQLEEGREVLSH 109
+T+ +R+ + E A ALR +E E
Sbjct: 263 PDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQ 322
Query: 110 LQAQRVELQAQTTT---LEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKSSYD 166
+Q+ E+ A T LE+ ++ E + E Y + I L+ EI+ + + + +
Sbjct: 323 VQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLRE 382
Query: 167 CRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIETPIPLFT 208
+ L + L E+ Y +++E E +R I P+P F+
Sbjct: 383 YQDLLNVKMALDIEIATYRKLLEGEESR-----ISLPLPNFS 419
>gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]
Length = 432
Score = 47.8 bits (112), Expect = 3e-05
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 36/248 (14%)
Query: 3 ENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYI 62
++E +L + L +EADEA L L L+ + + L+++I + H++ + E+Q +
Sbjct: 156 QDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQL 215
Query: 63 SILQQIIHTTPPASIVTSGMREEKLLTE--------------------------REVAAL 96
+ Q + +T+ ++E + E R L
Sbjct: 216 ARQQVHVELDVAKPDLTAALKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAELL 275
Query: 97 RSQLEEGREVLSHLQAQRVELQAQTTT---LEQAIKSAHECYDDEIQLYNEQIETLRKEI 153
R E + LQ+ +L++ T LE+ ++ E + E Y E + L +E
Sbjct: 276 RQAKHEANDYRRQLQSLTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEEG 335
Query: 154 EETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIETPIPLFT--QSH 211
+ + + + + + L + L E+ Y +++E E NR+T P+ F+ Q
Sbjct: 336 QSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRIT-----IPVQTFSNLQIR 390
Query: 212 GVSLSTGS 219
SL T S
Sbjct: 391 ETSLDTKS 398
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 47.4 bits (111), Expect = 3e-05
Identities = 62/293 (21%), Positives = 112/293 (38%), Gaps = 44/293 (15%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 61
YENE ++ + L + DE L +L+ + L ++++ K H++ + +Q
Sbjct: 179 YENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCA 238
Query: 62 ISILQQIIHTTPPA---SIVTSGMREE-KLLTERE------------------------- 92
+ P +++ + MR E + L E+
Sbjct: 239 AGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGA 298
Query: 93 VAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNEQIETLRKE 152
RSQL E R L L+ Q L A +LE ++ Y ++ QI L ++
Sbjct: 299 ATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQ 358
Query: 153 IEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIETPIPLFTQSHG 212
+ + E + L + L+ E++ Y R+I+ +GN + ++ G
Sbjct: 359 LHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSK----------SKGFG 408
Query: 213 VSLSTGSGGKDLTRALQDITAAK---PRQKALPKNVPRRKEIITKDKTNGALE 262
S S G+ KDL++ T + R K L + +E +K TNG E
Sbjct: 409 -SGSPGNSSKDLSKTTLVKTVVEELDQRGKVLSSRIHSIEEKTSK-MTNGKTE 459
>gi|14249342 internexin neuronal intermediate filament protein,
alpha [Homo sapiens]
Length = 499
Score = 47.4 bits (111), Expect = 3e-05
Identities = 44/215 (20%), Positives = 87/215 (40%), Gaps = 32/215 (14%)
Query: 16 LERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQI---IHTT 72
L+ ++ D A L L L+ + + L D+++ + H + + E+ + Q + T
Sbjct: 196 LKAQQRDVDGATLARLDLEKKVESLLDELAFVRQVHDEEVAELLATLQASSQAAAEVDVT 255
Query: 73 PPASIVTSGMREEKLLTE--------------------------REVAALRSQLEEGREV 106
+TS +RE + E R A+R+ EE E
Sbjct: 256 VAKPDLTSALREIRAQYESLAAKNLQSAEEWYKSKFANLNEQAARSTEAIRASREEIHEY 315
Query: 107 LSHLQAQRVE---LQAQTTTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERVLEKS 163
LQA+ +E L+ +LE+ I E + E+ Y + I L ++ T+ + +
Sbjct: 316 RRQLQARTIEIEGLRGANESLERQILELEERHSAEVAGYQDSIGQLENDLRNTKSEMARH 375
Query: 164 SYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSA 198
+ + L + L E+ Y +++E E R +++
Sbjct: 376 LREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTS 410
>gi|155969697 keratin 6C [Homo sapiens]
Length = 564
Score = 47.0 bits (110), Expect = 4e-05
Identities = 55/264 (20%), Positives = 102/264 (38%), Gaps = 61/264 (23%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 61
YE+E + + L K+ D A ++ + LQ +A L D+I+ + + L ++QT+
Sbjct: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312
Query: 62 ISILQQIIHTTPPASI------------------------------------VTSGMREE 85
IS ++ ++ VT+G +
Sbjct: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGD 372
Query: 86 KLL-TEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNE 144
L T++E+A + ++ R + H++ Q LQA EQ + A
Sbjct: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMA------------- 419
Query: 145 QIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKN-------ELDRYHRIIEIEGNRLTS 197
++ + ++E E L+K+ D +L Q L N E+ Y +++E E RL
Sbjct: 420 -LKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNG 478
Query: 198 AFIETPIPLFTQSHGVSLSTGSGG 221
+ QS ++S+G GG
Sbjct: 479 EGVGQVNVSVVQS---TISSGYGG 499
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 47.0 bits (110), Expect = 4e-05
Identities = 69/331 (20%), Positives = 137/331 (41%), Gaps = 49/331 (14%)
Query: 30 NLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIH-----------TTPPASIV 78
+++LQ + + LQ++ AA ++ KK L + ++ L + I T P +
Sbjct: 72 DVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQ 131
Query: 79 TSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDE 138
S + E E+ ++ +L+E E++S LQAQ + QA+ +
Sbjct: 132 LSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQ 191
Query: 139 IQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRL--- 195
+Q E I TL+ ++ +T+ AQQ ++ + R+ + + + L
Sbjct: 192 LQEKEEFISTLQAQLSQTQAE-----------QAAQQVVREKDARFETQVRLHEDELLQL 240
Query: 196 -TSAFIETP-------IPLFTQSHGVSLSTGSGGKDLTRALQDITAAKPRQKALPKNVPR 247
T A +ET + + H SL + DL + Q++TAA+ R + L + + +
Sbjct: 241 VTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQ--QELTAAEQRNQILSQQLQQ 298
Query: 248 RKEIITKDKTNGALEDAPLKGLEDTK-LVQVVLKEESESK--FESESKEVSPLTQEGAPE 304
+ + L + E++K L++ + E +E K F + +E+ L E
Sbjct: 299 ------MEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLL-----E 347
Query: 305 DVPDGGQISKGFGKLYRKVKEKVRSPKEPET 335
GQ Y +++K ++ E +T
Sbjct: 348 QFEQAGQAQAELESRYSALEQKHKAEMEEKT 378
Score = 36.2 bits (82), Expect = 0.078
Identities = 31/153 (20%), Positives = 67/153 (43%), Gaps = 12/153 (7%)
Query: 11 LLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIH 70
LLK+ E+ ++ AL++ L L+++++ KD KK + +T +++
Sbjct: 983 LLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE 1042
Query: 71 TTP-PASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIK 129
VTS +E ++ ++ ++ +L+ R+ L A + QA + Q ++
Sbjct: 1043 NKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQ 1102
Query: 130 SAHECYDDEIQLYNEQIETLRKEIEETERVLEK 162
QI+ L+ EI E + +++K
Sbjct: 1103 DK-----------TNQIDLLQAEISENQAIIQK 1124
Score = 35.8 bits (81), Expect = 0.10
Identities = 76/438 (17%), Positives = 172/438 (39%), Gaps = 43/438 (9%)
Query: 16 LERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHTTPPA 75
+E L E D+ L + LQ + + + V+ S ++++
Sbjct: 812 IEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQK 871
Query: 76 SIVTSGMREEKLLTEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECY 135
+ + M + L +R+V L+ +EE + ++ + E Q + ++ +
Sbjct: 872 ELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTL 931
Query: 136 DDEIQLYNEQIETLRKEIEETERVLE--KSSYDCRQLA--VAQQTLKNELDRYHRIIEIE 191
+++ L + E ++++EE V K +YD A ++++ L++E D + E
Sbjct: 932 KEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQR 991
Query: 192 GNRLTSAFIETPIPLFTQSHGVSLSTGSGGKDLTRALQDITAAKPR-QKALPKNVPRRKE 250
+L +A I L + ++R +++ K +K +P + R E
Sbjct: 992 KRKLQAALINRKELL---------------QRVSRLEEELANLKDESKKEIPLSETERGE 1036
Query: 251 IITKDKTNGALEDAPLKGLEDTKLVQVVLKEESESKFESESKEVSPLTQEGAPEDVPDGG 310
+ +DK N + + + +++ LK+ K E E + + +D+ +
Sbjct: 1037 -VEEDKENKEYSEKCV--TSKCQEIEIYLKQTISEK-EVELQHIR--------KDLEEKL 1084
Query: 311 QISKGFGKLYRKVKEKVRSPKEPETPTELYTKERHVLVTGDANYVDPRFYVSSITAKGGV 370
+ F L +++ + ++ + E ++ + S+ A G
Sbjct: 1085 AAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAII--------QKLITSNTDASDGD 1136
Query: 371 AVSVAEDSVLYDGQVEPSPESPKPPLENGQVGLQ-EKEDGQPIDQQPID--KEIEPDGAE 427
+V++ +++V+ S E KP LE + L+ EKE Q Q+ + K I E
Sbjct: 1137 SVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQE 1196
Query: 428 LEGPEEKREGEERDEESR 445
E + +++D+ +R
Sbjct: 1197 KERHLREELKQQKDDYNR 1214
Score = 32.7 bits (73), Expect = 0.86
Identities = 51/216 (23%), Positives = 90/216 (41%), Gaps = 36/216 (16%)
Query: 12 LKEMLERLNKE-------ADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISI 64
L E L+ + KE D + LQ + + D ++RH +LE +
Sbjct: 2441 LMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKD---QL 2497
Query: 65 LQQIIHTTPPASIVTSGMREEKLLTEREVAALRSQLEEGREVLSHL-------QAQRVEL 117
+Q+ G+R E A L ++L + RE L+ + Q Q +E+
Sbjct: 2498 IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEV 2557
Query: 118 QAQTTT--------LEQAIKSAHECYDDEIQLYN---EQIETLRKEIEETERVLEKSSYD 166
Q Q LE+ +K + E +D + +N E+ + L KEIE + + + +
Sbjct: 2558 QLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT-- 2615
Query: 167 CRQLAVAQQTLKNELDRYH---RIIEIEGNRLTSAF 199
RQ+ Q+ + L YH ++ E E +RL++ F
Sbjct: 2616 -RQVTALQE--EGTLGLYHAQLKVKEEEVHRLSALF 2648
Score = 32.0 bits (71), Expect = 1.5
Identities = 48/235 (20%), Positives = 94/235 (40%), Gaps = 47/235 (20%)
Query: 11 LLKEMLERLNKEADEALLHN---------LRLQLEA-----QFLQDDISAAK-------- 48
LL+E ++L E D +LL N L+L LE + L +I + K
Sbjct: 1543 LLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEST 1602
Query: 49 ---DRHKKNLLEVQTYISILQQIIHTTPPASIVTSGMREEKLL--------------TER 91
++HK+ E + + + + + V +R+EK TE+
Sbjct: 1603 EWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEK 1662
Query: 92 EVAALRSQLEEGREVLSHL----QAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNEQIE 147
++ ++EE +E + Q + +EL+ + L + A + + ++
Sbjct: 1663 QLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNA 1722
Query: 148 TLRKEIEETERVLEKSSYDCRQLAVAQQTLKNEL-DRYHRIIEIEGNRLTSAFIE 201
++++E+E + E S + L + +L E+ D H +IEGN A +E
Sbjct: 1723 SMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKH---QIEGNVSKQANLE 1774
Score = 30.4 bits (67), Expect = 4.3
Identities = 43/211 (20%), Positives = 85/211 (40%), Gaps = 33/211 (15%)
Query: 7 ECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQ 66
E +LL EM KEA E + L+LQL+ + ++ D+ + +E + I
Sbjct: 558 ELSVLLLEM-----KEAQEEIAF-LKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKM 611
Query: 67 QII--------------HTTPPASIVTSGMREEKLLTEREVAA------LRSQLEEGREV 106
++ ++ PA E + T E++ L+S ++G +
Sbjct: 612 KVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKS 671
Query: 107 LSHL-------QAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNEQIETLRKEIEETERV 159
LS + Q + L++Q LE A E Y+ + ++I L + IEE ++
Sbjct: 672 LSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKN 731
Query: 160 LEKSSYDCRQLAVAQQTLKNELDRYHRIIEI 190
+ +S L+ + L +++ + E+
Sbjct: 732 ADNNSSAFTALSEERDQLLSQVKELSMVTEL 762
Score = 30.0 bits (66), Expect = 5.6
Identities = 35/197 (17%), Positives = 84/197 (42%), Gaps = 19/197 (9%)
Query: 12 LKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTYISILQQIIHT 71
L+E+L+ +E + +R Q + L+ + A + ++ +++ L Q +
Sbjct: 2010 LQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEH 2069
Query: 72 TPPASIVTSGMREEKLLTEREVA-ALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKS 130
A + + T+ E A L L+ +E+ S+ ++ + +++ + LE+ ++
Sbjct: 2070 RKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ 2129
Query: 131 AHECYDDEIQLYNEQIETLRKEI------------------EETERVLEKSSYDCRQLAV 172
A E + E + E+++ LR+E +E +++ E QLA
Sbjct: 2130 AEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAA 2189
Query: 173 AQQTLKNELDRYHRIIE 189
+++ + D R+I+
Sbjct: 2190 FTKSMSSLQDDRDRVID 2206
>gi|194018511 keratin 77 [Homo sapiens]
Length = 578
Score = 46.6 bits (109), Expect = 6e-05
Identities = 49/250 (19%), Positives = 110/250 (44%), Gaps = 31/250 (12%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 61
YE+E + + L K+ D A + + L+ L +++ K L +VQT+
Sbjct: 254 YEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTH 313
Query: 62 ISILQQII-----HTTPPASIVTSGMREEKLLTER---EVAAL----------------- 96
IS I+ + SI+ + + +L+ +R E AL
Sbjct: 314 ISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGD 373
Query: 97 -----RSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNEQIETLRK 151
+ ++ E + LQA+ ++ Q ++ I A E + +Q ++++ L +
Sbjct: 374 DLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEE 433
Query: 152 EIEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTSAFIETPIPLFTQSH 211
+++++ L + D + + + +L E+ Y +++E E +R+ S +++ + + Q+
Sbjct: 434 ALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRM-SGELQSHVSISVQNS 492
Query: 212 GVSLSTGSGG 221
VS++ G+GG
Sbjct: 493 QVSVNGGAGG 502
>gi|14917119 keratin 34 [Homo sapiens]
Length = 436
Score = 46.6 bits (109), Expect = 6e-05
Identities = 43/223 (19%), Positives = 93/223 (41%), Gaps = 29/223 (13%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNL------ 55
Y+ E +LL++ + + + DE L L+ + + L++++ K H++ +
Sbjct: 187 YQTEQSLRLLVESDINSIRRILDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQ 246
Query: 56 ------LEVQTYISI-LQQIIHTTPPA--SIVTSGMREEKLLTEREVAALRSQLEEGREV 106
+EV T ++ L Q+++ T ++V RE + + L Q+ E
Sbjct: 247 LGDRLNVEVDTAPTVDLNQVLNETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQ 306
Query: 107 LSHLQAQRVELQAQTTTLEQAIKSAHEC--------------YDDEIQLYNEQIETLRKE 152
L QA+ +EL+ LE +++ H Y ++ I + +
Sbjct: 307 LQSCQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQ 366
Query: 153 IEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRL 195
+ E LE+ + + + L + L+ E++ Y ++E E +L
Sbjct: 367 LAEIRCDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKL 409
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 46.6 bits (109), Expect = 6e-05
Identities = 43/225 (19%), Positives = 94/225 (41%), Gaps = 29/225 (12%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNL------ 55
Y+ E + L++ + L + DE L L+ + + L++++ + K H++ +
Sbjct: 145 YQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQ 204
Query: 56 ------LEVQTYISI-LQQIIHTTPPA--SIVTSGMREEKLLTEREVAALRSQLEEGREV 106
+EV ++ L Q+++ T ++V + RE + + L Q+ E
Sbjct: 205 LGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQ 264
Query: 107 LSHLQAQRVELQAQTTTLEQAIKSAHEC--------------YDDEIQLYNEQIETLRKE 152
L QA+ +EL+ LE +++ H Y ++ I + +
Sbjct: 265 LQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQ 324
Query: 153 IEETERVLEKSSYDCRQLAVAQQTLKNELDRYHRIIEIEGNRLTS 197
+ E LE+ + + + L + L+ E++ Y ++E E +L S
Sbjct: 325 LAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPS 369
>gi|5031839 keratin 6A [Homo sapiens]
Length = 564
Score = 46.2 bits (108), Expect = 8e-05
Identities = 55/264 (20%), Positives = 102/264 (38%), Gaps = 61/264 (23%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 61
YE+E + + L K+ D A ++ + LQ +A L D+I+ + + L ++QT+
Sbjct: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312
Query: 62 ISILQQIIHTTPPASI------------------------------------VTSGMREE 85
IS ++ ++ VT+G +
Sbjct: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGD 372
Query: 86 KLL-TEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNE 144
L T++E+A + ++ R + H++ Q LQA EQ + A
Sbjct: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMA------------- 419
Query: 145 QIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKN-------ELDRYHRIIEIEGNRLTS 197
++ + ++E E L+K+ D +L Q L N E+ Y +++E E RL
Sbjct: 420 -LKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNG 478
Query: 198 AFIETPIPLFTQSHGVSLSTGSGG 221
+ QS ++S+G GG
Sbjct: 479 EGVGQVNISVVQS---TVSSGYGG 499
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 23/164 (14%)
Query: 34 QLEAQFLQDDISAAKDRHKK----NLLEVQTYISILQQIIHTTPPASIVTSGMREEKLLT 89
Q E Q L+ ISA + + K L E + I+ L+ + +TSGM
Sbjct: 296 QKEIQSLKSQISALQKGYSKVLCQTLSERNSEITSLKNEGENLKRDNAITSGMVSS---L 352
Query: 90 EREVAALRSQLEEGREVLSHLQAQRVELQAQTTTL-------------EQAIKSAHECYD 136
++++ A Q+++ +E +SHL++Q + Q L E A + E +
Sbjct: 353 QKDILAKDEQVQQLKEEVSHLKSQNKDKDHQLEALGSRCSVLKEELKQEDAHRELREAQE 412
Query: 137 DEIQLYNEQIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKNE 180
E++L QI+ + KE+++ L KS C + +V +TL+ +
Sbjct: 413 KELKLCKTQIQDMEKEMKKLRAELRKS---CTEQSVISRTLREK 453
>gi|119703753 keratin 6B [Homo sapiens]
Length = 564
Score = 45.8 bits (107), Expect = 1e-04
Identities = 54/264 (20%), Positives = 102/264 (38%), Gaps = 61/264 (23%)
Query: 2 YENECECQLLLKEMLERLNKEADEALLHNLRLQLEAQFLQDDISAAKDRHKKNLLEVQTY 61
YE+E + + L K+ D A ++ + LQ +A L D+I+ + + L ++QT+
Sbjct: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312
Query: 62 ISILQQIIHTTPPASI------------------------------------VTSGMREE 85
IS ++ ++ +T+G +
Sbjct: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGD 372
Query: 86 KLL-TEREVAALRSQLEEGREVLSHLQAQRVELQAQTTTLEQAIKSAHECYDDEIQLYNE 144
L T++E+A + ++ R + H++ Q LQA EQ + A
Sbjct: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMA------------- 419
Query: 145 QIETLRKEIEETERVLEKSSYDCRQLAVAQQTLKN-------ELDRYHRIIEIEGNRLTS 197
++ + ++E E L+K+ D +L Q L N E+ Y +++E E RL
Sbjct: 420 -LKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNG 478
Query: 198 AFIETPIPLFTQSHGVSLSTGSGG 221
+ QS ++S+G GG
Sbjct: 479 EGVGQVNISVVQS---TVSSGYGG 499
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.128 0.344
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,130,171
Number of Sequences: 37866
Number of extensions: 1180347
Number of successful extensions: 9108
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 776
Number of HSP's that attempted gapping in prelim test: 6897
Number of HSP's gapped (non-prelim): 2605
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.