Guide to the Human Genome
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Search of human proteins with 239757810

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239757810 PREDICTED: similar to protein phosphatase 1,
regulatory (inhibitor) subunit 3F [Homo sapiens]
         (724 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239757810 PREDICTED: similar to protein phosphatase 1, regula...  1483   0.0  
gi|58761532 protein phosphatase 1, regulatory (inhibitor) subuni...  1369   0.0  
gi|167614502 protein phosphatase 1, regulatory (inhibitor) subun...    80   7e-15
gi|153792466 protein phosphatase 1, regulatory (inhibitor) subun...    54   4e-07
gi|223278393 protein phosphatase 1, regulatory (inhibitor) subun...    54   7e-07
gi|5453948 protein phosphatase 1, regulatory subunit 3D [Homo sa...    49   2e-05
gi|4885559 protein phosphatase 1, regulatory (inhibitor) subunit...    48   4e-05
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                47   5e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   1e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   1e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    46   1e-04
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    45   2e-04
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...    44   7e-04
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H...    44   7e-04
gi|50962882 G patch domain containing 8 [Homo sapiens]                 43   9e-04
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    42   0.002
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    42   0.002
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    42   0.002
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s...    41   0.003
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa...    41   0.003
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    41   0.004
gi|110624765 POU domain, class 3, transcription factor 1 [Homo s...    41   0.004
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    40   0.006
gi|28274705 family with sequence similarity 9, member A [Homo sa...    40   0.006
gi|169215908 PREDICTED: family with sequence similarity 108, mem...    40   0.008
gi|169215726 PREDICTED: family with sequence similarity 108, mem...    40   0.008
gi|239746656 PREDICTED: hypothetical protein LOC729495 [Homo sap...    40   0.008
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    39   0.013
gi|11415052 retinoid X receptor, beta [Homo sapiens]                   39   0.017
gi|45504380 jumonji domain containing 2B [Homo sapiens]                39   0.022

>gi|239757810 PREDICTED: similar to protein phosphatase 1,
           regulatory (inhibitor) subunit 3F [Homo sapiens]
          Length = 724

 Score = 1483 bits (3839), Expect = 0.0
 Identities = 724/724 (100%), Positives = 724/724 (100%)

Query: 1   MARTAPVEPPLRHSAPPSPAAGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGP 60
           MARTAPVEPPLRHSAPPSPAAGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGP
Sbjct: 1   MARTAPVEPPLRHSAPPSPAAGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGP 60

Query: 61  GAGKMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFS 120
           GAGKMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFS
Sbjct: 61  GAGKMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFS 120

Query: 121 LPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVH 180
           LPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVH
Sbjct: 121 LPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVH 180

Query: 181 VRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASASSPDDGGRT 240
           VRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASASSPDDGGRT
Sbjct: 181 VRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASASSPDDGGRT 240

Query: 241 DRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLP 300
           DRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLP
Sbjct: 241 DRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLP 300

Query: 301 QQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDDNTFAMAEHPDVQ 360
           QQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDDNTFAMAEHPDVQ
Sbjct: 301 QQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDDNTFAMAEHPDVQ 360

Query: 361 ESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPS 420
           ESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPS
Sbjct: 361 ESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPS 420

Query: 421 SPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSEELLG 480
           SPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSEELLG
Sbjct: 421 SPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSEELLG 480

Query: 481 EDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPSHPLGILTDRDLILKWPG 540
           EDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPSHPLGILTDRDLILKWPG
Sbjct: 481 EDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPSHPLGILTDRDLILKWPG 540

Query: 541 PERALNSALAEEITLHYARLGRGVELIKDTEDPDDEGEGEEGLSVTPSSPEGDSPKESPP 600
           PERALNSALAEEITLHYARLGRGVELIKDTEDPDDEGEGEEGLSVTPSSPEGDSPKESPP
Sbjct: 541 PERALNSALAEEITLHYARLGRGVELIKDTEDPDDEGEGEEGLSVTPSSPEGDSPKESPP 600

Query: 601 EILSGARSVVATMGDVWLPWAEGSGCDGPVVLGTEGQFIGDPEKGMGKDTSSLHMNRVIA 660
           EILSGARSVVATMGDVWLPWAEGSGCDGPVVLGTEGQFIGDPEKGMGKDTSSLHMNRVIA
Sbjct: 601 EILSGARSVVATMGDVWLPWAEGSGCDGPVVLGTEGQFIGDPEKGMGKDTSSLHMNRVIA 660

Query: 661 GVTESKSPTLAVPAECVCALPPQLRGPLTQTLGVLAGLVVVPVALNSGVSLLVLALCLSL 720
           GVTESKSPTLAVPAECVCALPPQLRGPLTQTLGVLAGLVVVPVALNSGVSLLVLALCLSL
Sbjct: 661 GVTESKSPTLAVPAECVCALPPQLRGPLTQTLGVLAGLVVVPVALNSGVSLLVLALCLSL 720

Query: 721 AWFS 724
           AWFS
Sbjct: 721 AWFS 724


>gi|58761532 protein phosphatase 1, regulatory (inhibitor) subunit
           3F [Homo sapiens]
          Length = 799

 Score = 1369 bits (3543), Expect = 0.0
 Identities = 665/665 (100%), Positives = 665/665 (100%)

Query: 1   MARTAPVEPPLRHSAPPSPAAGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGP 60
           MARTAPVEPPLRHSAPPSPAAGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGP
Sbjct: 1   MARTAPVEPPLRHSAPPSPAAGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGP 60

Query: 61  GAGKMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFS 120
           GAGKMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFS
Sbjct: 61  GAGKMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFS 120

Query: 121 LPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVH 180
           LPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVH
Sbjct: 121 LPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVH 180

Query: 181 VRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASASSPDDGGRT 240
           VRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASASSPDDGGRT
Sbjct: 181 VRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASASSPDDGGRT 240

Query: 241 DRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLP 300
           DRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLP
Sbjct: 241 DRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLP 300

Query: 301 QQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDDNTFAMAEHPDVQ 360
           QQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDDNTFAMAEHPDVQ
Sbjct: 301 QQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDDNTFAMAEHPDVQ 360

Query: 361 ESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPS 420
           ESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPS
Sbjct: 361 ESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPS 420

Query: 421 SPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSEELLG 480
           SPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSEELLG
Sbjct: 421 SPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSEELLG 480

Query: 481 EDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPSHPLGILTDRDLILKWPG 540
           EDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPSHPLGILTDRDLILKWPG
Sbjct: 481 EDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPSHPLGILTDRDLILKWPG 540

Query: 541 PERALNSALAEEITLHYARLGRGVELIKDTEDPDDEGEGEEGLSVTPSSPEGDSPKESPP 600
           PERALNSALAEEITLHYARLGRGVELIKDTEDPDDEGEGEEGLSVTPSSPEGDSPKESPP
Sbjct: 541 PERALNSALAEEITLHYARLGRGVELIKDTEDPDDEGEGEEGLSVTPSSPEGDSPKESPP 600

Query: 601 EILSGARSVVATMGDVWLPWAEGSGCDGPVVLGTEGQFIGDPEKGMGKDTSSLHMNRVIA 660
           EILSGARSVVATMGDVWLPWAEGSGCDGPVVLGTEGQFIGDPEKGMGKDTSSLHMNRVIA
Sbjct: 601 EILSGARSVVATMGDVWLPWAEGSGCDGPVVLGTEGQFIGDPEKGMGKDTSSLHMNRVIA 660

Query: 661 GVTES 665
           GVTES
Sbjct: 661 GVTES 665



 Score =  118 bits (296), Expect = 2e-26
 Identities = 59/59 (100%), Positives = 59/59 (100%)

Query: 666 KSPTLAVPAECVCALPPQLRGPLTQTLGVLAGLVVVPVALNSGVSLLVLALCLSLAWFS 724
           KSPTLAVPAECVCALPPQLRGPLTQTLGVLAGLVVVPVALNSGVSLLVLALCLSLAWFS
Sbjct: 741 KSPTLAVPAECVCALPPQLRGPLTQTLGVLAGLVVVPVALNSGVSLLVLALCLSLAWFS 799


>gi|167614502 protein phosphatase 1, regulatory (inhibitor) subunit
           3A [Homo sapiens]
          Length = 1122

 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 68/250 (27%), Positives = 108/250 (43%), Gaps = 76/250 (30%)

Query: 113 FYLVPTFSLPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLN 172
           + L P F LP +    E L + +   +A+L    ++ G   +          +G++RVLN
Sbjct: 104 YVLAPLFDLPSSK---EDLMQQLQIQKAILESTESLLGSTSI----------KGIIRVLN 150

Query: 173 RSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASAS 232
            SFEK V+VR S D W +  D  A YVP S                              
Sbjct: 151 VSFEKLVYVRMSLDDWQTHYDILAEYVPNSCD---------------------------- 182

Query: 233 SPDDGGRTDRFAFQL----PFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIA 288
                G TD+F+F++    P+ +   DG++++F +RYET  GTFW+NN+G NYT +    
Sbjct: 183 -----GETDQFSFKIVLVPPYQK---DGSKVEFCIRYETSVGTFWSNNNGTNYTFIC--- 231

Query: 289 PAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDD 348
                          Q  + EP+P  +   E   RQ+K C+K      + +E  +   ++
Sbjct: 232 ---------------QKKEQEPEP-VKPWKEVPNRQIKGCLKV----KSSKEESSVTSEE 271

Query: 349 NTFAMAEHPD 358
           N F   ++ D
Sbjct: 272 NNFENPKNTD 281


>gi|153792466 protein phosphatase 1, regulatory (inhibitor) subunit
           3B [Homo sapiens]
          Length = 285

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 32/121 (26%)

Query: 164 LRGLVRVLNRSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLG 223
           + G V+V N +FEK V +R + D W S+ D P +YV     +AG+               
Sbjct: 145 IAGTVKVQNLAFEKTVKIRMTFDTWKSYTDFPCQYV--KDTYAGSD-------------- 188

Query: 224 LGPGQASASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTV 283
                            D F+F +   E      R++F V YE    T+W +N G+NY +
Sbjct: 189 ----------------RDTFSFDISLPEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRI 232

Query: 284 L 284
           +
Sbjct: 233 I 233


>gi|223278393 protein phosphatase 1, regulatory (inhibitor) subunit
           3G [Homo sapiens]
          Length = 358

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 57/182 (31%), Positives = 69/182 (37%), Gaps = 42/182 (23%)

Query: 115 LVPTFSLPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRS 174
           L P F LP      ERL R  V LE +     +   GA V          +G  RVL+  
Sbjct: 197 LRPLFQLPGPSAAAERLQRQRVCLERV---QCSTASGAEV----------KGSGRVLSCP 243

Query: 175 FEKAVHVRASHDGWASFCDHPARYVPR----SPPWA--GAGGTGAGDPILDPG------- 221
             +AV VR +   W SF D PA   P       P A  GA   G+GD   +PG       
Sbjct: 244 GPRAVTVRYTFTEWRSFLDVPAELQPEPLEPQQPEAPSGASEPGSGDAKKEPGAECFHFS 303

Query: 222 LGLGPGQASASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNY 281
           L L PG       D   R                G  + F V Y   +G +W NN G NY
Sbjct: 304 LCLPPGLQPEDEEDADER----------------GVAVHFAVCYRCAQGEYWDNNAGANY 347

Query: 282 TV 283
           T+
Sbjct: 348 TL 349


>gi|5453948 protein phosphatase 1, regulatory subunit 3D [Homo
           sapiens]
          Length = 299

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 73/287 (25%), Positives = 98/287 (34%), Gaps = 66/287 (22%)

Query: 16  PPSPAAGEPRTSVEAAVAPR-RVLFADEALGLPLAQLRRYRPWGGPGAG----------- 63
           P SP    P T   +   PR R +    A  LP +  RR +  G PGA            
Sbjct: 44  PGSPGRAPPPTPAPSGCDPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQKLRV 103

Query: 64  KMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYL---VPTFS 120
           + A A G +          + G+D              S LC       F L   VP F 
Sbjct: 104 RFADALGLELAQ---VKVFNAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFP 160

Query: 121 LPPAPGRL-ERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAV 179
            P       ERL R +V LE +      + G                 VRV N +FEK V
Sbjct: 161 PPVEAADFGERLQRQLVCLERVTCSDLGISG----------------TVRVCNVAFEKQV 204

Query: 180 HVRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASASSPDDGGR 239
            VR +  GW S  +  AR       W G  G    + +   G  + P             
Sbjct: 205 AVRYTFSGWRSTHEAVAR-------WRGPAGPEGTEDVFTFGFPVPP------------- 244

Query: 240 TDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLR 286
              F  +L        G+R+ F VRY+     +W NN  R+Y++  R
Sbjct: 245 ---FLLEL--------GSRVHFAVRYQVAGAEYWDNNDHRDYSLTCR 280


>gi|4885559 protein phosphatase 1, regulatory (inhibitor) subunit 3C
           [Homo sapiens]
          Length = 317

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 36/158 (22%), Positives = 57/158 (36%), Gaps = 33/158 (20%)

Query: 166 GLVRVLNRSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLG 225
           G V+V N SFEK V +R + D W ++ D    Y+         GGT +            
Sbjct: 171 GTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNV-----YGGTDS------------ 213

Query: 226 PGQASASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLL 285
                          D F+F +          +++F + Y      FW NN G+NY + +
Sbjct: 214 ---------------DTFSFAIDLPPVIPTEQKIEFCISYHANGQVFWDNNDGQNYRI-V 257

Query: 286 RIAPAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEAR 323
            +   P     +  PQ     Q  P+ E +  +    R
Sbjct: 258 HVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPR 295


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 54/197 (27%), Positives = 70/197 (35%), Gaps = 9/197 (4%)

Query: 282 TVLLRIAPAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEEL 341
           TV  R+A    P+ A   P     P   P P    P  A A   +     V  RPA    
Sbjct: 489 TVSDRLASEELPSTAVPTPATTPAPAPAPAP-APAPALASAATKERTESEVPPRPASP-- 545

Query: 342 KTKNMDDNTFAMAEHPDVQESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGD--VPR 399
           K       T A  E  D+           P  P PQ++   S  P    P   G    P+
Sbjct: 546 KVTRSPPETAAPVE--DMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQ 603

Query: 400 SSPPVAFTEVLQAPAIR--IPPSSPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEA 457
           + P       L+AP +   +PP+ P      S R  AS   AS G   P        A+ 
Sbjct: 604 ALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQV 663

Query: 458 TWGVSSENGGGLEAVSG 474
             G ++  GG  EA+SG
Sbjct: 664 DLGAATAEGGAPEAISG 680


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 38/137 (27%), Positives = 56/137 (40%), Gaps = 4/137 (2%)

Query: 401 SPPVAFTEVLQAPAIRIPPSSPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWG 460
           +PP+AF     AP    P + P    G     +  GP+++  A G  L+P      +   
Sbjct: 676 APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA-LDPGPSPGTSGGK 734

Query: 461 VSSENGGGLEAVSGSEELLGE---DTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTD 517
            ++  G G  + S  +  LGE     +   + Q  LS    L AA  A G  GGG G  +
Sbjct: 735 AAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 794

Query: 518 GGMSPSHPLGILTDRDL 534
           GG         L+D +L
Sbjct: 795 GGGVTGGARAALSDAEL 811



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 52/211 (24%), Positives = 69/211 (32%), Gaps = 34/211 (16%)

Query: 289 PAPTPTDAEGLPQQQQLP-------QLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEEL 341
           PA  P      P  Q  P       Q+ P P    P+   A        P+   P +   
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ--- 511

Query: 342 KTKNMDDNTFAMAEHPDVQESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSS 401
                      +A+ P       P +A  PL+  P               A     P ++
Sbjct: 512 -----------LAKPPP---QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 557

Query: 402 PPVAFTEVLQAPAIRIPPSSPLCGLGGSP-RDQASGPDASEG--------ATGPFLEPSQ 452
           PP     VL AP +++PPS P      +P R    GPD S          A GP   PS+
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617

Query: 453 QQAEATWGVSSENGGGLEAVSGSEELLGEDT 483
             +    G     G    A S  EEL G D+
Sbjct: 618 SPSSTLSGPDLA-GHSSSATSTPEELRGYDS 647


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 38/137 (27%), Positives = 56/137 (40%), Gaps = 4/137 (2%)

Query: 401  SPPVAFTEVLQAPAIRIPPSSPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWG 460
            +PP+AF     AP    P + P    G     +  GP+++  A G  L+P      +   
Sbjct: 945  APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA-LDPGPSPGTSGGK 1003

Query: 461  VSSENGGGLEAVSGSEELLGE---DTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTD 517
             ++  G G  + S  +  LGE     +   + Q  LS    L AA  A G  GGG G  +
Sbjct: 1004 AAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 1063

Query: 518  GGMSPSHPLGILTDRDL 534
            GG         L+D +L
Sbjct: 1064 GGGVTGGARAALSDAEL 1080



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 52/207 (25%), Positives = 68/207 (32%), Gaps = 13/207 (6%)

Query: 289 PAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRP---AEEELKTKN 345
           PA  P      P  Q  P L   P    P    +  +     P  R P   A   L+   
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770

Query: 346 MDDNTFAMAEHPDVQESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVA 405
               +  M+          P +A  PL+  P               A     P ++PP  
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830

Query: 406 FTEVLQAPAIRIPPSSPLCGLGGSP-RDQASGPDASEG--------ATGPFLEPSQQQAE 456
              VL AP +++PPS P      +P R    GPD S          A GP   PS+  + 
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 890

Query: 457 ATWGVSSENGGGLEAVSGSEELLGEDT 483
              G     G    A S  EEL G D+
Sbjct: 891 TLSGPDLA-GHSSSATSTPEELRGYDS 916



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 6/68 (8%)

Query: 357 PDVQESVGPLVAPTPLRPWPQMT--LQVSDVPMTGNPAEEGDVPRSSPPVAFTEVLQAPA 414
           P     + P   P P  P P     LQV   P    PA     P ++PP     +L AP 
Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSP----PASPPMSPSATPPPRVPPLLAAPP 765

Query: 415 IRIPPSSP 422
           +++PPS P
Sbjct: 766 LQVPPSPP 773



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 38/155 (24%), Positives = 52/155 (33%), Gaps = 21/155 (13%)

Query: 289 PAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDD 348
           PA      +GLP     P   P P  Q P       L++   P    PA   L       
Sbjct: 596 PALASPPLQGLPSPPLSPLATPPP--QAPPXLALPPLQAPPSP----PASPPLSP----- 644

Query: 349 NTFAMAEHPDVQESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTE 408
                   P    ++   +   P  P P   +Q    P    P      P ++PP     
Sbjct: 645 ---LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS----PSATPPSQAPP 697

Query: 409 VLQAPAIRIPPS---SPLCGLGGSPRDQASGPDAS 440
            L AP +++PPS   SP      +P  QA  P A+
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 30/109 (27%), Positives = 39/109 (35%), Gaps = 12/109 (11%)

Query: 359 VQESVGPLVAPTP------LRPWPQMTLQVSDVPMTGNPAEE----GDVPRSSPPVAFTE 408
           +Q    PL  P P        P PQ    ++  P+ G P+         P  +PP     
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALP 628

Query: 409 VLQAPAIRIPPSSPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEA 457
            LQAP    PP+SP      +P  QA    A      PF  P     +A
Sbjct: 629 PLQAPP--SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 675



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 42/178 (23%), Positives = 56/178 (31%), Gaps = 25/178 (14%)

Query: 292 TPTDAEGLPQQQQLPQLEPQP--ECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDDN 349
           TP  +   P  + LP L P P      P+     +   C  P   +     L T   +  
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584

Query: 350 TFAMAEHPDVQESVG-------------PLVAPTPLRPWPQMTL---QVSDVPMTGNPAE 393
           +      P    ++              PL  P P  P P + L   Q    P    P  
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP-PXLALPPLQAPPSPPASPPLS 643

Query: 394 EGDVPRSSPPVAFT-EVLQAPAIRIPPSSPLCGLGGSPRDQASGPDASEGATGPFLEP 450
               P    P A    +LQAP    PPS P+     +P    + P  S  AT P   P
Sbjct: 644 PLATPSPQAPNALAVHLLQAP-FSPPPSPPV----QAPFSPPASPPVSPSATPPSQAP 696


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 38/137 (27%), Positives = 56/137 (40%), Gaps = 4/137 (2%)

Query: 401 SPPVAFTEVLQAPAIRIPPSSPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWG 460
           +PP+AF     AP    P + P    G     +  GP+++  A G  L+P      +   
Sbjct: 637 APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA-LDPGPSPGTSGGK 695

Query: 461 VSSENGGGLEAVSGSEELLGE---DTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTD 517
            ++  G G  + S  +  LGE     +   + Q  LS    L AA  A G  GGG G  +
Sbjct: 696 AAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE 755

Query: 518 GGMSPSHPLGILTDRDL 534
           GG         L+D +L
Sbjct: 756 GGGVTGGARAALSDAEL 772



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 52/211 (24%), Positives = 69/211 (32%), Gaps = 34/211 (16%)

Query: 289 PAPTPTDAEGLPQQQQLP-------QLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEEL 341
           PA  P      P  Q  P       Q+ P P    P+   A        P+   P +   
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ--- 472

Query: 342 KTKNMDDNTFAMAEHPDVQESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSS 401
                      +A+ P       P +A  PL+  P               A     P ++
Sbjct: 473 -----------LAKPPP---QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 518

Query: 402 PPVAFTEVLQAPAIRIPPSSPLCGLGGSP-RDQASGPDASEG--------ATGPFLEPSQ 452
           PP     VL AP +++PPS P      +P R    GPD S          A GP   PS+
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578

Query: 453 QQAEATWGVSSENGGGLEAVSGSEELLGEDT 483
             +    G     G    A S  EEL G D+
Sbjct: 579 SPSSTLSGPDLA-GHSSSATSTPEELRGYDS 608


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 23/49 (46%), Positives = 27/49 (55%), Gaps = 3/49 (6%)

Query: 53   RYRPWGGPGAGKMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEP 101
            R  PW G  AG   AA G+ GG G     ++DGED DE EEE+E    P
Sbjct: 1278 RRPPWEGADAG---AAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAP 1323



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 112/452 (24%), Positives = 142/452 (31%), Gaps = 97/452 (21%)

Query: 17   PSPAAGEP--RTSVEAAVAPRRVLFA---DEALGLPLAQL-----------RRYRPWGG- 59
            P+P  GEP   TS+E A AP  V+ +    E    PL              RR    GG 
Sbjct: 1068 PAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGA 1127

Query: 60   ---PGAGKMAAAAG----------QDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCP 106
               PGAG++   +G            GG G G D      D    +      P P PL P
Sbjct: 1128 PRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQ------PPPPPLPP 1181

Query: 107  VPAGGGFYLVPTFSLPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRG 166
             P            L PAP R     R  V  E     P +  GG       G PP    
Sbjct: 1182 PPE------AQPRRLEPAPPR----ARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPER 1231

Query: 167  LVRVLNRSF---------EKAVHVRASHDGWA----SFCDHPARYVPRSPPWAGAGGTGA 213
                + R F          + +  R S    A    +    P    PR PPW GA    A
Sbjct: 1232 KGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGP-GPRRPPWEGADAGAA 1290

Query: 214  GDPILDPGLGLGPGQASASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFW 273
            G      G   GP +      D+    D  A     A GA  G R               
Sbjct: 1291 GGEAGGAG-APGPAEEDGEDEDEDEEEDEEA----AAPGAAAGPR--------------- 1330

Query: 274  ANNHGRNYTVLLRIAPAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVR 333
                GR      R AP P    +      + L  L   P  +G  E E  +L+   K V 
Sbjct: 1331 --GPGR-----ARAAPVPVVVSSADADAARPLRGLLKSP--RGADEPEDSELERKRKMVS 1381

Query: 334  -RRPAEEELKTKNMDDNTFAMAEHP--DVQESVGPLVAPTPLRP-WPQMTLQVSDVPMTG 389
                    L  +    N  ++   P  D   S  P   PTP  P  P      +D    G
Sbjct: 1382 FHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPP-APPTPPHPATPGDGFPSNDSGFGG 1440

Query: 390  NPAEEGD---VPRSSPPVAFTEVLQAPAIRIP 418
            +     D   +P   PP+ F+    +PA+  P
Sbjct: 1441 SFEWAEDFPLLPPPGPPLCFSRFSVSPALETP 1472


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
           [Homo sapiens]
          Length = 828

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 52/185 (28%), Positives = 73/185 (39%), Gaps = 27/185 (14%)

Query: 286 RIAPAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQ-LKSCMKPVRR---RPAEEEL 341
           ++ P P P   +  PQ Q  PQL PQP+ Q      A Q  +    PV     +P  E  
Sbjct: 405 KLQPQPQP---QPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELE 461

Query: 342 KTKNMDDNTFAMAEHPDVQESVGPLVAP-TPLRPWPQMTLQVSDVPMTGNPAEE-GDVPR 399
               ++     + E  DV E  GP+  P +P R  P +  +   VP     A    ++PR
Sbjct: 462 PEPEIEGLLTPVLEAGDVDE--GPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPR 519

Query: 400 SSPPVAFTEVLQAPAIRIPPS---------SPLCGLGGSPRDQASGPDASEGATGPFLEP 450
             P      + QAPA+ +PP+         S L    G P     GP   E    P  E 
Sbjct: 520 --PLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGP-----GPGGPEPELSPITEG 572

Query: 451 SQQQA 455
           S+ +A
Sbjct: 573 SEARA 577



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 37/155 (23%), Positives = 61/155 (39%), Gaps = 28/155 (18%)

Query: 292 TPTDAEGLPQQQQLP----------QLEPQPECQG---PV----EAEARQLKSCMKPVRR 334
           TPT A   PQQ   P          +LEP+PE +G   PV    + +   +   + P R 
Sbjct: 434 TPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRL 493

Query: 335 RPA--EEELKTKNMDDNTFAMAEHP-------DVQESVGPLVAPTPLRPWPQMTLQVSDV 385
           +PA   E      +++    +AE P        ++++    + PT  + + Q+  ++   
Sbjct: 494 QPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFH- 552

Query: 386 PMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPS 420
              G P   G  P  SP    +E    P    PP+
Sbjct: 553 -RHGGPGPGGPEPELSPITEGSEARAGPPAPAPPA 586


>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
           sapiens]
          Length = 828

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 52/185 (28%), Positives = 73/185 (39%), Gaps = 27/185 (14%)

Query: 286 RIAPAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQ-LKSCMKPVRR---RPAEEEL 341
           ++ P P P   +  PQ Q  PQL PQP+ Q      A Q  +    PV     +P  E  
Sbjct: 405 KLQPQPQP---QPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELE 461

Query: 342 KTKNMDDNTFAMAEHPDVQESVGPLVAP-TPLRPWPQMTLQVSDVPMTGNPAEE-GDVPR 399
               ++     + E  DV E  GP+  P +P R  P +  +   VP     A    ++PR
Sbjct: 462 PEPEIEGLLTPVLEAGDVDE--GPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPR 519

Query: 400 SSPPVAFTEVLQAPAIRIPPS---------SPLCGLGGSPRDQASGPDASEGATGPFLEP 450
             P      + QAPA+ +PP+         S L    G P     GP   E    P  E 
Sbjct: 520 --PLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGP-----GPGGPEPELSPITEG 572

Query: 451 SQQQA 455
           S+ +A
Sbjct: 573 SEARA 577



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 37/155 (23%), Positives = 61/155 (39%), Gaps = 28/155 (18%)

Query: 292 TPTDAEGLPQQQQLP----------QLEPQPECQG---PV----EAEARQLKSCMKPVRR 334
           TPT A   PQQ   P          +LEP+PE +G   PV    + +   +   + P R 
Sbjct: 434 TPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRL 493

Query: 335 RPA--EEELKTKNMDDNTFAMAEHP-------DVQESVGPLVAPTPLRPWPQMTLQVSDV 385
           +PA   E      +++    +AE P        ++++    + PT  + + Q+  ++   
Sbjct: 494 QPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFH- 552

Query: 386 PMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPS 420
              G P   G  P  SP    +E    P    PP+
Sbjct: 553 -RHGGPGPGGPEPELSPITEGSEARAGPPAPAPPA 586


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 58/227 (25%), Positives = 88/227 (38%), Gaps = 29/227 (12%)

Query: 418 PPSSPLCGLGGSPRDQAS-GPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSE 476
           P ++P    G SP+ ++     AS+GA     E S+Q  E +    SE G   EA    +
Sbjct: 428 PKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEA----K 483

Query: 477 ELLGEDTIDQELE----QLYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPSHPL--GILT 530
           + LG D  DQ LE    ++  + +    ++     A   G+ S +G   P+ P    +  
Sbjct: 484 KALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSK 543

Query: 531 DRDLILKWPGPERALNSALAEEITLHYA--------RLGRGVEL-IKDTEDPDDEGEGEE 581
           D    L+WP        A   E ++ Y+        +L R  +   K TE P D G    
Sbjct: 544 DESTALQWPSELLIFTKA---EPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIG---- 596

Query: 582 GLSVTPSSPEGDSPKESPPEILSGARSVVATMGDVWLPWAEGSGCDG 628
             S +    +G  P E       G   +V + G      A GS C G
Sbjct: 597 --SSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSG 641


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 59/237 (24%), Positives = 82/237 (34%), Gaps = 16/237 (6%)

Query: 12  RHSAPPSPAAGEPRT-SVEAAVAPRRV-LFADEALGLPLAQLRRYRPWGGPGAGKMAAAA 69
           +H    SP  G   + S  AA AP  +    +   G P +Q   Y  +  PGAG      
Sbjct: 196 QHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG 255

Query: 70  GQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFSLPPAPGRLE 129
           G  GGG GG         G  G     A    +       GGG Y   +          +
Sbjct: 256 GGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ 315

Query: 130 RLGRVMVEL----EALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVHVRASH 185
           + G +M+       A L    A     G     G+     G    LN+       +  S+
Sbjct: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSY 375

Query: 186 DGWASFCDHPARYVPRSPP-----WAGAGGTGAGDPILDPGLGLGP---GQASASSP 234
            G  S+ ++ +   P  PP      A A G  AG      G+GLG     Q +A+SP
Sbjct: 376 GG--SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP 430



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 63/224 (28%), Positives = 78/224 (34%), Gaps = 48/224 (21%)

Query: 73  GGGGGGADEDD-DGEDGDEGEEEEEAC-----PEPSPLCPVPAGGGFYLVPTFSLPPAPG 126
           GG GGGA +   D E    G  ++ A      P   PL   P  G     P     PA G
Sbjct: 83  GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP--GDEDDAPPKMGEPAGG 140

Query: 127 RLERLGRVMVELEALLPPPGAVPGGAG--VWVP--------------------------- 157
           R E  G   +  +    PP AVPGG G    VP                           
Sbjct: 141 RYEHPGLGALGTQQ---PPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197

Query: 158 GGRPPVLRGLVRVLNRSFEKAVH----VRASHDGWA-SFCDHPARYVPRSPPWAGAGGTG 212
           GG+     G++   + +   A      ++ SH+G+  S C+H   Y   S P AG GG G
Sbjct: 198 GGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGY---SRPGAGGGGGG 254

Query: 213 AGDPILDPGLGLGPGQASASSPDDGGRTDRFAFQLPFAEGAGDG 256
            G      G G G G A A     G      A     A G G G
Sbjct: 255 GGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGG 298



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 37/154 (24%), Positives = 45/154 (29%), Gaps = 26/154 (16%)

Query: 386 PMTGNPAEEGDVP---------RSSPPVAFTEVLQAPAIRIPPSSPLCGLGGSPR----- 431
           P+   P +E D P         R   P       Q P + +P      G GG P      
Sbjct: 119 PLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVP------GGGGGPAAVPEF 172

Query: 432 -----DQASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSEELLGEDTIDQ 486
                  A       G  GP  +    Q     G+            GS + L       
Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGY 232

Query: 487 ELEQL-YLSHLSRLRAAVAAGGAGGGGEGSTDGG 519
              Q  +    SR  A    GG GGGG GS  GG
Sbjct: 233 PNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG 266


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 59/237 (24%), Positives = 82/237 (34%), Gaps = 16/237 (6%)

Query: 12  RHSAPPSPAAGEPRT-SVEAAVAPRRV-LFADEALGLPLAQLRRYRPWGGPGAGKMAAAA 69
           +H    SP  G   + S  AA AP  +    +   G P +Q   Y  +  PGAG      
Sbjct: 196 QHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG 255

Query: 70  GQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFSLPPAPGRLE 129
           G  GGG GG         G  G     A    +       GGG Y   +          +
Sbjct: 256 GGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ 315

Query: 130 RLGRVMVEL----EALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVHVRASH 185
           + G +M+       A L    A     G     G+     G    LN+       +  S+
Sbjct: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSY 375

Query: 186 DGWASFCDHPARYVPRSPP-----WAGAGGTGAGDPILDPGLGLGP---GQASASSP 234
            G  S+ ++ +   P  PP      A A G  AG      G+GLG     Q +A+SP
Sbjct: 376 GG--SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP 430



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 63/224 (28%), Positives = 78/224 (34%), Gaps = 48/224 (21%)

Query: 73  GGGGGGADEDD-DGEDGDEGEEEEEAC-----PEPSPLCPVPAGGGFYLVPTFSLPPAPG 126
           GG GGGA +   D E    G  ++ A      P   PL   P  G     P     PA G
Sbjct: 83  GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP--GDEDDAPPKMGEPAGG 140

Query: 127 RLERLGRVMVELEALLPPPGAVPGGAG--VWVP--------------------------- 157
           R E  G   +  +    PP AVPGG G    VP                           
Sbjct: 141 RYEHPGLGALGTQQ---PPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197

Query: 158 GGRPPVLRGLVRVLNRSFEKAVH----VRASHDGWA-SFCDHPARYVPRSPPWAGAGGTG 212
           GG+     G++   + +   A      ++ SH+G+  S C+H   Y   S P AG GG G
Sbjct: 198 GGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGY---SRPGAGGGGGG 254

Query: 213 AGDPILDPGLGLGPGQASASSPDDGGRTDRFAFQLPFAEGAGDG 256
            G      G G G G A A     G      A     A G G G
Sbjct: 255 GGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGG 298



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 37/154 (24%), Positives = 45/154 (29%), Gaps = 26/154 (16%)

Query: 386 PMTGNPAEEGDVP---------RSSPPVAFTEVLQAPAIRIPPSSPLCGLGGSPR----- 431
           P+   P +E D P         R   P       Q P + +P      G GG P      
Sbjct: 119 PLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVP------GGGGGPAAVPEF 172

Query: 432 -----DQASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSEELLGEDTIDQ 486
                  A       G  GP  +    Q     G+            GS + L       
Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGY 232

Query: 487 ELEQL-YLSHLSRLRAAVAAGGAGGGGEGSTDGG 519
              Q  +    SR  A    GG GGGG GS  GG
Sbjct: 233 PNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG 266


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 59/237 (24%), Positives = 82/237 (34%), Gaps = 16/237 (6%)

Query: 12  RHSAPPSPAAGEPRT-SVEAAVAPRRV-LFADEALGLPLAQLRRYRPWGGPGAGKMAAAA 69
           +H    SP  G   + S  AA AP  +    +   G P +Q   Y  +  PGAG      
Sbjct: 196 QHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG 255

Query: 70  GQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFSLPPAPGRLE 129
           G  GGG GG         G  G     A    +       GGG Y   +          +
Sbjct: 256 GGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ 315

Query: 130 RLGRVMVEL----EALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVHVRASH 185
           + G +M+       A L    A     G     G+     G    LN+       +  S+
Sbjct: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSY 375

Query: 186 DGWASFCDHPARYVPRSPP-----WAGAGGTGAGDPILDPGLGLGP---GQASASSP 234
            G  S+ ++ +   P  PP      A A G  AG      G+GLG     Q +A+SP
Sbjct: 376 GG--SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP 430



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 63/224 (28%), Positives = 78/224 (34%), Gaps = 48/224 (21%)

Query: 73  GGGGGGADEDD-DGEDGDEGEEEEEAC-----PEPSPLCPVPAGGGFYLVPTFSLPPAPG 126
           GG GGGA +   D E    G  ++ A      P   PL   P  G     P     PA G
Sbjct: 83  GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP--GDEDDAPPKMGEPAGG 140

Query: 127 RLERLGRVMVELEALLPPPGAVPGGAG--VWVP--------------------------- 157
           R E  G   +  +    PP AVPGG G    VP                           
Sbjct: 141 RYEHPGLGALGTQQ---PPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197

Query: 158 GGRPPVLRGLVRVLNRSFEKAVH----VRASHDGWA-SFCDHPARYVPRSPPWAGAGGTG 212
           GG+     G++   + +   A      ++ SH+G+  S C+H   Y   S P AG GG G
Sbjct: 198 GGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGY---SRPGAGGGGGG 254

Query: 213 AGDPILDPGLGLGPGQASASSPDDGGRTDRFAFQLPFAEGAGDG 256
            G      G G G G A A     G      A     A G G G
Sbjct: 255 GGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGG 298



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 37/154 (24%), Positives = 45/154 (29%), Gaps = 26/154 (16%)

Query: 386 PMTGNPAEEGDVP---------RSSPPVAFTEVLQAPAIRIPPSSPLCGLGGSPR----- 431
           P+   P +E D P         R   P       Q P + +P      G GG P      
Sbjct: 119 PLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVP------GGGGGPAAVPEF 172

Query: 432 -----DQASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSEELLGEDTIDQ 486
                  A       G  GP  +    Q     G+            GS + L       
Sbjct: 173 NNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGY 232

Query: 487 ELEQL-YLSHLSRLRAAVAAGGAGGGGEGSTDGG 519
              Q  +    SR  A    GG GGGG GS  GG
Sbjct: 233 PNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG 266


>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
           sapiens]
          Length = 1235

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 44/160 (27%), Positives = 59/160 (36%), Gaps = 28/160 (17%)

Query: 288 APAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMD 347
           AP+P P   +      Q P L  QP  QGP EA   QL+   +P  +RP   +  T+ + 
Sbjct: 317 APSPDPDLVQRTEAPPQPPPLSTQPP-QGPPEA---QLQPAPQPQVQRPPRPQSPTQLLH 372

Query: 348 DNTFAMAEHPDVQESVGPLVA-PTPLRPWPQMTLQVSDVPMTGNPAEEG----------- 395
            N   +  HP  Q    PL A  +       ++   S  P    PA              
Sbjct: 373 QNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFP 432

Query: 396 -DVPRSSPPVAFTEVLQ-----------APAIRIPPSSPL 423
             +P  SP  +FT  LQ           AP   +PP  PL
Sbjct: 433 LSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPL 472


>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
           sapiens]
          Length = 1259

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 44/160 (27%), Positives = 59/160 (36%), Gaps = 28/160 (17%)

Query: 288 APAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMD 347
           AP+P P   +      Q P L  QP  QGP EA   QL+   +P  +RP   +  T+ + 
Sbjct: 317 APSPDPDLVQRTEAPPQPPPLSTQPP-QGPPEA---QLQPAPQPQVQRPPRPQSPTQLLH 372

Query: 348 DNTFAMAEHPDVQESVGPLVA-PTPLRPWPQMTLQVSDVPMTGNPAEEG----------- 395
            N   +  HP  Q    PL A  +       ++   S  P    PA              
Sbjct: 373 QNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFP 432

Query: 396 -DVPRSSPPVAFTEVLQ-----------APAIRIPPSSPL 423
             +P  SP  +FT  LQ           AP   +PP  PL
Sbjct: 433 LSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPL 472


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 43/164 (26%), Positives = 56/164 (34%), Gaps = 24/164 (14%)

Query: 289 PAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDD 348
           P P P   +  P  QQ P  +P P  Q P   +  Q +    P +             D 
Sbjct: 61  PPPPPHQQQQQPPPQQPPPQQPPPH-QPPPHPQPHQQQQPPPPPQ-------------DS 106

Query: 349 NTFAMAEHPDVQESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTE 408
           +   +A+ P     VG   AP      P  T      P +G P   G  P  +PP A T 
Sbjct: 107 SKPVVAQGPGPAPGVGS--APPASSSAPPAT-----PPTSGAPPGSGPGPTPTPPPAVT- 158

Query: 409 VLQAPAIRIPPSSPLCGLGGSPRDQASGPDASEGATGPFLEPSQ 452
              AP    PP+ P  G+  +P      P       GP   P Q
Sbjct: 159 --SAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQ 200


>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
           sapiens]
          Length = 451

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 68/263 (25%), Positives = 84/263 (31%), Gaps = 61/263 (23%)

Query: 10  PLRH---SAPPSPAAGEPRTSVEAAVAPRRVLFADEALGL----PLAQLR-RYRPWGGPG 61
           PL H   +A  + AA   R    AA    + L   E LG     P+     ++ P GG G
Sbjct: 21  PLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAGHPVGLAHPQWLPTGGGG 80

Query: 62  AGKMAAAA----GQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVP 117
            G  A       G+ GGGG G  +D  G                        GGGF+   
Sbjct: 81  GGDWAGGPHLEHGKAGGGGTGRADDGGG------------------------GGGFHARL 116

Query: 118 TFSLPPAPGRLERLGRVMVEL-EALLPPPGAVPGG--------AGVWVPGGRPPVLRGLV 168
                   G     G     L  A+ P PGA  G         A    PGG    L G++
Sbjct: 117 VHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGML 176

Query: 169 RVLNRSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAG----------AGGTGAGDPIL 218
                     +H     DG      H A+  P  PP  G          AGG  A    L
Sbjct: 177 AAGGGGAGPGLHHALHEDG------HEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHL 230

Query: 219 DPGLGLGPGQASASSPDDGGRTD 241
            PG G G       S +D   +D
Sbjct: 231 HPGAGGGGSSVGEHSDEDAPSSD 253


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
            sapiens]
          Length = 1336

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 64/230 (27%), Positives = 74/230 (32%), Gaps = 59/230 (25%)

Query: 6    PVEPPLRHSAPPSPAAGEPRTSVEAAVAPR--RVLFADEALGLPLAQLRRYRPWGGPGAG 63
            P EPP   + P  P+   P  +   AV P   R+ F DE+   P A+  R  P   P  G
Sbjct: 1016 PAEPPAG-AFPGFPSPPAPPAAAATAVGPPLCRLAFEDESPPAP-ARWPRSDPESQPLLG 1073

Query: 64   KMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFSLPP 123
              A  AG  GG GGGA                 A P P    P P        P   L P
Sbjct: 1074 PGAGGAGGTGGAGGGA----------------PAAPPPCRAAPPPC-------PYLDLEP 1110

Query: 124  APG---RLERLGRVMV--------------ELEALLPPPGAV-----PGG--AGVW---V 156
            +P      E LG   +                E L PPPG        GG  AG W    
Sbjct: 1111 SPSDSEDSESLGGASLGGLEPWWFADFPYPYAERLGPPPGRYWSVDKLGGWRAGSWDYLP 1170

Query: 157  PGGRPPVLRGLVRVLNRSFEKAVHVRASHDGWASFCDHPARYVPRSPPWA 206
            P   P                  H+  SHDG          + P  PPWA
Sbjct: 1171 PRSGPAAWHCRHCASLELLPPPRHLSCSHDGLDG-----GWWAPPPPPWA 1215


>gi|28274705 family with sequence similarity 9, member A [Homo
           sapiens]
          Length = 332

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 24/82 (29%), Positives = 38/82 (46%)

Query: 15  APPSPAAGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGPGAGKMAAAAGQDGG 74
           A  + AA E   + EAA A   V+  ++       +          G  +     G++GG
Sbjct: 194 AEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGG 253

Query: 75  GGGGADEDDDGEDGDEGEEEEE 96
           GGG  +E ++ E+ +E EEEEE
Sbjct: 254 GGGEGEETEEEEEEEEEEEEEE 275


>gi|169215908 PREDICTED: family with sequence similarity 108, member
           A5 [Homo sapiens]
          Length = 403

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 47/142 (33%), Positives = 52/142 (36%), Gaps = 38/142 (26%)

Query: 55  RPWGGPGAGKMAAAAGQD------GGGGGGADEDDDGEDGDEGEEE--EEACPE---PSP 103
           RPWG PGA    A    D          GG D D  G     G        CP    P P
Sbjct: 12  RPWG-PGARAGVAFPRHDMETCGCEAPWGGLDRDGAGPWPPNGAAVWGSHPCPRLGAPPP 70

Query: 104 L-CPV---------PAGGGFYLVPT------------FSLPPAPGRLE-RLGRVMVELE- 139
           L CP          P GG     P             F  PP PGR+  +L  +  E   
Sbjct: 71  LPCPARPGGVVGGGPGGGPAREAPAMNGLSLSELCCLFCYPPCPGRIAAKLAFLPPEATY 130

Query: 140 ALLPPPGAVPGGAGVWVPGGRP 161
           +L+P PG  PGGAG W   GRP
Sbjct: 131 SLVPEPG--PGGAGAWWGRGRP 150


>gi|169215726 PREDICTED: family with sequence similarity 108, member
           A5 [Homo sapiens]
          Length = 403

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 47/142 (33%), Positives = 52/142 (36%), Gaps = 38/142 (26%)

Query: 55  RPWGGPGAGKMAAAAGQD------GGGGGGADEDDDGEDGDEGEEE--EEACPE---PSP 103
           RPWG PGA    A    D          GG D D  G     G        CP    P P
Sbjct: 12  RPWG-PGARAGVAFPRHDMETCGCEAPWGGLDRDGAGPWPPNGAAVWGSHPCPRLGAPPP 70

Query: 104 L-CPV---------PAGGGFYLVPT------------FSLPPAPGRLE-RLGRVMVELE- 139
           L CP          P GG     P             F  PP PGR+  +L  +  E   
Sbjct: 71  LPCPARPGGVVGGGPGGGPAREAPAMNGLSLSELCCLFCYPPCPGRIAAKLAFLPPEATY 130

Query: 140 ALLPPPGAVPGGAGVWVPGGRP 161
           +L+P PG  PGGAG W   GRP
Sbjct: 131 SLVPEPG--PGGAGAWWGRGRP 150


>gi|239746656 PREDICTED: hypothetical protein LOC729495 [Homo
           sapiens]
          Length = 403

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 47/142 (33%), Positives = 52/142 (36%), Gaps = 38/142 (26%)

Query: 55  RPWGGPGAGKMAAAAGQD------GGGGGGADEDDDGEDGDEGEEE--EEACPE---PSP 103
           RPWG PGA    A    D          GG D D  G     G        CP    P P
Sbjct: 12  RPWG-PGARAGVAFPRHDMETCGCEAPWGGLDRDGAGPWPPNGAAVWGSHPCPRLGAPPP 70

Query: 104 L-CPV---------PAGGGFYLVPT------------FSLPPAPGRLE-RLGRVMVELE- 139
           L CP          P GG     P             F  PP PGR+  +L  +  E   
Sbjct: 71  LPCPARPGGVVGGGPGGGPAREAPAMNGLSLSELCCLFCYPPCPGRIAAKLAFLPPEATY 130

Query: 140 ALLPPPGAVPGGAGVWVPGGRP 161
           +L+P PG  PGGAG W   GRP
Sbjct: 131 SLVPEPG--PGGAGAWWGRGRP 150


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 39.3 bits (90), Expect = 0.013
 Identities = 59/273 (21%), Positives = 99/273 (36%), Gaps = 30/273 (10%)

Query: 277 HGRNYTVLLRIAPAPTPTDAEGL----PQQQQLPQLEPQPECQGPVEAEARQLKSCMKPV 332
           HGRN++ + R+  + T +  +       ++Q L ++  Q + +   E  AR+ K      
Sbjct: 630 HGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAA 689

Query: 333 RRRPA-------EEELKTKNMDDNTFAMAEHPD--VQESVGPLVAPTPLR---------- 373
               A       +EE++   +  N   M E  +  V  S      P+P            
Sbjct: 690 ASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNG 749

Query: 374 PWPQMTLQVSDVPMTGNPAEEG-DVPRSSPPVAFTEVLQAPAIRIPPSSPLCGLGGSPRD 432
           P P  TL  +D P  G P     D+P  + P   +E   AP     P SP       P++
Sbjct: 750 PKPPATLG-ADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKE 808

Query: 433 QASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSG--SEELLGEDTIDQELEQ 490
           +    +    A  P  E  +Q+  A   ++ + G   E V    +EE        ++ E 
Sbjct: 809 E---KEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEA 865

Query: 491 LYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPS 523
              +    L+A    GG+G      + G    S
Sbjct: 866 AEATAEGALKAEKKEGGSGRATTAKSSGAPQDS 898


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 46/153 (30%), Positives = 60/153 (39%), Gaps = 37/153 (24%)

Query: 52  RRYRPWGGPGAGKMAAAAGQD----GGGGGGADEDDDGEDGDEGEEEEEACPEPSPL-CP 106
           RR RPW  P A   AA AG +        G A  D  G+ G +    + + P P P   P
Sbjct: 37  RRRRPWLDPAAAAAAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVP 96

Query: 107 VPAGGGFYLVPTF--------SLPPAPGRLERLGRVMVELEALLP----PPGAVPGGAG- 153
            P+  G  L P+         + PP P     LG     + + +     PP A PG +G 
Sbjct: 97  PPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGP 156

Query: 154 ---------VWVPGG--------RPPVL--RGL 167
                    V +PGG        +PPVL  RGL
Sbjct: 157 VSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGL 189


>gi|45504380 jumonji domain containing 2B [Homo sapiens]
          Length = 1096

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 35/107 (32%), Positives = 46/107 (42%), Gaps = 9/107 (8%)

Query: 60  PGAGKMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTF 119
           PG G   AA  ++ GG   + +++ G + D  EEEE    EP PL       G       
Sbjct: 391 PGEGTAGAALLEEAGG---SVKEEAGPEVDPEEEEE----EPQPLPHGREAEGAEEDGRG 443

Query: 120 SLPPAPGRLERLGRVMVELEALLPPPGA-VPGGAGVWVPGG-RPPVL 164
            L P   + ER  +    L   LPPP A  P    +W+P    PPVL
Sbjct: 444 KLRPTKAKSERKKKSFGLLPPQLPPPPAHFPSEEALWLPSPLEPPVL 490


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.135    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,234,552
Number of Sequences: 37866
Number of extensions: 2503426
Number of successful extensions: 18830
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 446
Number of HSP's that attempted gapping in prelim test: 14797
Number of HSP's gapped (non-prelim): 3704
length of query: 724
length of database: 18,247,518
effective HSP length: 110
effective length of query: 614
effective length of database: 14,082,258
effective search space: 8646506412
effective search space used: 8646506412
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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