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Search of human proteins with 239757637
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo
sapiens]
(344 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo sa... 709 0.0
gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo sap... 647 0.0
gi|32313610 ubiquitin specific protease 18 [Homo sapiens] 627 e-180
gi|169215723 PREDICTED: ubiquitin specific peptidase 41 [Homo sa... 605 e-173
gi|71774197 ubiquitin specific protease 47 [Homo sapiens] 140 1e-33
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 98 1e-20
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] 98 1e-20
gi|149192845 ubiquitin specific protease 24 [Homo sapiens] 96 5e-20
gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens] 90 3e-18
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 89 7e-18
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 89 7e-18
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 89 7e-18
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 85 8e-17
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 85 8e-17
gi|110347427 ubiquitin specific protease 34 [Homo sapiens] 85 1e-16
gi|183396780 ubiquitin specific protease 20 [Homo sapiens] 84 1e-16
gi|183397136 ubiquitin specific protease 20 [Homo sapiens] 84 1e-16
gi|183397134 ubiquitin specific protease 20 [Homo sapiens] 84 1e-16
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 80 3e-15
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 80 3e-15
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 80 3e-15
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 80 3e-15
gi|41055953 ubiquitin thioesterase 40 [Homo sapiens] 77 2e-14
gi|45267835 ubiquitin specific protease 50 [Homo sapiens] 76 5e-14
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 75 7e-14
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] 74 2e-13
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] 74 2e-13
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 73 3e-13
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] 72 7e-13
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] 72 7e-13
>gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo
sapiens]
Length = 344
Score = 709 bits (1830), Expect = 0.0
Identities = 344/344 (100%), Positives = 344/344 (100%)
Query: 1 MKQLQLFSVPKISWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADE 60
MKQLQLFSVPKISWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADE
Sbjct: 1 MKQLQLFSVPKISWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADE 60
Query: 61 QRRSVPFQMLLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQ 120
QRRSVPFQMLLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQ
Sbjct: 61 QRRSVPFQMLLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQ 120
Query: 121 IADVHLVERLQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALH 180
IADVHLVERLQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALH
Sbjct: 121 IADVHLVERLQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALH 180
Query: 181 CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLY 240
CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLY
Sbjct: 181 CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLY 240
Query: 241 FPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRSAVDGKWFCF 300
FPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRSAVDGKWFCF
Sbjct: 241 FPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRSAVDGKWFCF 300
Query: 301 NDSNICLVSWEDIQCTYGNPNYHWXETDLGNWSLMSSHRVLGAA 344
NDSNICLVSWEDIQCTYGNPNYHW ETDLGNWSLMSSHRVLGAA
Sbjct: 301 NDSNICLVSWEDIQCTYGNPNYHWXETDLGNWSLMSSHRVLGAA 344
>gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo
sapiens]
Length = 347
Score = 647 bits (1668), Expect = 0.0
Identities = 310/312 (99%), Positives = 312/312 (100%)
Query: 13 SWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLL 72
SWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLL
Sbjct: 36 SWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLL 95
Query: 73 LEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERLQA 132
LEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERLQA
Sbjct: 96 LEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERLQA 155
Query: 133 LYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSSKS 192
LYMIR+KDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSSKS
Sbjct: 156 LYMIRMKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSSKS 215
Query: 193 KCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILP 252
KCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILP
Sbjct: 216 KCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILP 275
Query: 253 MKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRSAVDGKWFCFNDSNICLVSWED 312
MKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR+AVDGKWFCFNDSNICLVSWED
Sbjct: 276 MKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWED 335
Query: 313 IQCTYGNPNYHW 324
IQCTYGNPNYHW
Sbjct: 336 IQCTYGNPNYHW 347
>gi|32313610 ubiquitin specific protease 18 [Homo sapiens]
Length = 372
Score = 627 bits (1618), Expect = e-180
Identities = 307/327 (93%), Positives = 312/327 (95%), Gaps = 1/327 (0%)
Query: 1 MKQLQLFSVPKISWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADE 60
MK+ Q P+ +WDY HGLVGLHNIGQTCCLNSLIQVFVMNVDF RILKRITVPRGADE
Sbjct: 36 MKREQPRERPR-AWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADE 94
Query: 61 QRRSVPFQMLLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQ 120
QRRSVPFQMLLLLEKMQDSRQKAV PLELAYCLQK NVPLFVQHDAAQLYLKLWNLIKDQ
Sbjct: 95 QRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQ 154
Query: 121 IADVHLVERLQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALH 180
I DVHLVERLQALY IRVKDSLIC+DCAMESSRNSSMLTL LS FDVDSKPLKTLEDALH
Sbjct: 155 ITDVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALH 214
Query: 181 CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLY 240
CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLY
Sbjct: 215 CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLY 274
Query: 241 FPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRSAVDGKWFCF 300
FPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR+AVDGKWFCF
Sbjct: 275 FPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCF 334
Query: 301 NDSNICLVSWEDIQCTYGNPNYHWXET 327
NDSNICLVSWEDIQCTYGNPNYHW ET
Sbjct: 335 NDSNICLVSWEDIQCTYGNPNYHWQET 361
>gi|169215723 PREDICTED: ubiquitin specific peptidase 41 [Homo
sapiens]
Length = 346
Score = 605 bits (1561), Expect = e-173
Identities = 294/296 (99%), Positives = 296/296 (100%)
Query: 13 SWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLL 72
SWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLL
Sbjct: 36 SWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLL 95
Query: 73 LEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERLQA 132
LEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERLQA
Sbjct: 96 LEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERLQA 155
Query: 133 LYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSSKS 192
LYMIR+KDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSSKS
Sbjct: 156 LYMIRMKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSSKS 215
Query: 193 KCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILP 252
KCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILP
Sbjct: 216 KCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILP 275
Query: 253 MKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRSAVDGKWFCFNDSNICLV 308
MKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR+AVDGKWFCFNDSNICLV
Sbjct: 276 MKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLV 331
>gi|71774197 ubiquitin specific protease 47 [Homo sapiens]
Length = 1287
Score = 140 bits (354), Expect = 1e-33
Identities = 96/366 (26%), Positives = 160/366 (43%), Gaps = 52/366 (14%)
Query: 5 QLFSVPKISWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRS 64
Q +S I G VGL N TC LNSL+Q M +F L + ++ S
Sbjct: 84 QSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTS 143
Query: 65 VPFQMLLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADV 124
+P+Q+ L +Q S+++A+ ++ + + QHD +L +++ ++ +
Sbjct: 144 IPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQT 203
Query: 125 HLVERLQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDV-DSKPLKTLEDALHCFF 183
+ + LY ++KD + CL+C E R + L + L S+ ++E+ALH F
Sbjct: 204 EQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFI 263
Query: 184 QPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR--KICHSLYF 241
QP L ++ FCE C KK ++ L+ H P LT+ L RF + K+ + F
Sbjct: 264 QPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTF 323
Query: 242 PQSLDFSQILPMKRE-----------------SCDAEEQSGG------------------ 266
P+ LD S + ++ E SC +++ S
Sbjct: 324 PEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSG 383
Query: 267 --------------QYELFAVIAHVGMADSGHYCVYIRSAVDGKWFCFNDSNICLVSWED 312
YELF+V+ H G A GHY I+S D +W+ FND ++ ++ ED
Sbjct: 384 TEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQED 443
Query: 313 IQCTYG 318
I+ T+G
Sbjct: 444 IKKTHG 449
>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
Length = 485
Score = 97.8 bits (242), Expect = 1e-20
Identities = 81/308 (26%), Positives = 137/308 (44%), Gaps = 37/308 (12%)
Query: 17 RHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRIT-----------VPRGADEQRRSV 65
++ VGL N+G TC +N+ +QV+ +N++ + L + D + +++
Sbjct: 85 KNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTI 144
Query: 66 PFQMLLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIA--- 122
+ L +Q+S ++ + P L + Q DA + +L++D ++
Sbjct: 145 CEHLQYLFALLQNSNRRYIDPSGFVKAL---GLDTGQQQDAQEFSKLFMSLLEDTLSKQK 201
Query: 123 --DVHLVERLQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALH 180
DV + +Q + +C C ES S L L+ + K L D +
Sbjct: 202 NPDVRNI--VQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNI-----QGHKQLTDCIS 254
Query: 181 CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLY 240
F + +L ++ FCENC K + ++L LP TL + LMRF R+ H
Sbjct: 255 EFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVF----DRQTGHKKK 310
Query: 241 FPQSLDFSQILPMKRESCDAEEQSGGQ--YELFAVIAHVGM-ADSGHYCVYIRSAVDGKW 297
+ FS+IL M+ E GG YEL AV+ H G+ A SGHY +++ G+W
Sbjct: 311 LNTYIGFSEILDME----PYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEW 366
Query: 298 FCFNDSNI 305
+ FND +I
Sbjct: 367 YKFNDEDI 374
>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
Length = 1035
Score = 97.8 bits (242), Expect = 1e-20
Identities = 81/308 (26%), Positives = 137/308 (44%), Gaps = 37/308 (12%)
Query: 17 RHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRIT-----------VPRGADEQRRSV 65
++ VGL N+G TC +N+ +QV+ +N++ + L + D + +++
Sbjct: 85 KNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQTI 144
Query: 66 PFQMLLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIA--- 122
+ L +Q+S ++ + P L + Q DA + +L++D ++
Sbjct: 145 CEHLQYLFALLQNSNRRYIDPSGFVKAL---GLDTGQQQDAQEFSKLFMSLLEDTLSKQK 201
Query: 123 --DVHLVERLQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALH 180
DV + +Q + +C C ES S L L+ + K L D +
Sbjct: 202 NPDVRNI--VQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNI-----QGHKQLTDCIS 254
Query: 181 CFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLY 240
F + +L ++ FCENC K + ++L LP TL + LMRF R+ H
Sbjct: 255 EFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVF----DRQTGHKKK 310
Query: 241 FPQSLDFSQILPMKRESCDAEEQSGGQ--YELFAVIAHVGM-ADSGHYCVYIRSAVDGKW 297
+ FS+IL M+ E GG YEL AV+ H G+ A SGHY +++ G+W
Sbjct: 311 LNTYIGFSEILDME----PYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEW 366
Query: 298 FCFNDSNI 305
+ FND +I
Sbjct: 367 YKFNDEDI 374
>gi|149192845 ubiquitin specific protease 24 [Homo sapiens]
Length = 2460
Score = 95.9 bits (237), Expect = 5e-20
Identities = 85/325 (26%), Positives = 133/325 (40%), Gaps = 35/325 (10%)
Query: 9 VPKISWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQ 68
+P + G VGL N G TC +N++ Q M L ++V D SV +Q
Sbjct: 1517 LPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESL--LSVDDDTDNPDDSVFYQ 1574
Query: 69 MLLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFV--QHDAAQLYLKLWNLIKDQIADVHL 126
+ L + +S+ + P + +N L+V Q DA + + L + + + + +
Sbjct: 1575 VQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGR 1634
Query: 127 VERLQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPR 186
+ + + D IC DC R + + L L S LE +L F +
Sbjct: 1635 DQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQS-----LEISLDQFVRGE 1689
Query: 187 ELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSI--RNSQTRKICHSLYFPQS 244
L + +CE C +K + + LP L IHLMRF + ++ K + FP
Sbjct: 1690 VLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWM 1749
Query: 245 LDFS--QILPMKRESCDAE--------EQSGG-----------QYELFAVIAHVGMADSG 283
L+ + M R+ +E +Q GG YEL VI H G A +G
Sbjct: 1750 LNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHAG 1809
Query: 284 HYCVYI---RSAVDGKWFCFNDSNI 305
HY +I R GKW+ FND+ I
Sbjct: 1810 HYYSFIKDRRGCGKGKWYKFNDTVI 1834
>gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens]
Length = 1102
Score = 90.1 bits (222), Expect = 3e-18
Identities = 80/312 (25%), Positives = 133/312 (42%), Gaps = 20/312 (6%)
Query: 12 ISWDYRH--GLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQM 69
++WD + G VGL N G TC +NSL+Q + + +P D+ +SVP +
Sbjct: 203 VAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAV--YMMPTEGDDSSKSVPLAL 260
Query: 70 LLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVER 129
+ ++Q S K V +L + F+QHD +L L + +++++ +
Sbjct: 261 QRVFYELQHS-DKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGT 319
Query: 130 LQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELS 189
+ L+ ++ + C + S R ++LS K K + ++ + +L
Sbjct: 320 IPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSI-----KGKKNIFESFVDYVAVEQLD 374
Query: 190 SKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSI--RNSQTRKICHSLYFPQSLDF 247
+K G + K V LT LP L + LMRF + Q KI FP+ L
Sbjct: 375 GDNKYDAGEHGLQEAEKGVKFLT-LPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPL 433
Query: 248 SQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRSAVDGKWFCFNDSNICL 307
+ L + + Y L AV+ H G GHY VY+ DGKW F+D +
Sbjct: 434 DEFLQK------TDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSR 487
Query: 308 VSWED-IQCTYG 318
+ E+ I+ YG
Sbjct: 488 CTKEEAIEHNYG 499
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 88.6 bits (218), Expect = 7e-18
Identities = 75/332 (22%), Positives = 139/332 (41%), Gaps = 47/332 (14%)
Query: 20 LVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQ-----RRSVPFQMLLLLE 74
L GL N+G TC +NS++Q A R + + V + ++++
Sbjct: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
Query: 75 KMQDSRQKAVWPLELAYCLQKYNVPL--FVQHDAAQLYLKLWNLI--------------- 117
+ + + + P + + K N + Q D+ +L L L + +
Sbjct: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895
Query: 118 --KDQIADVHLVER------------LQALYMIRVKDSLICLDCAMESSRNSSMLTLRLS 163
D + D E + AL+ + K ++ CL C +S + + L L
Sbjct: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955
Query: 164 FFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLM 223
+ S TL+D L F + +L+ ++ +C +C + + +++ LP L +HL
Sbjct: 956 ---LASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLK 1012
Query: 224 RFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADS 282
RFS +K+ S+ FP ++LD SQ + + + +Y LF+V H G D
Sbjct: 1013 RFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLK-------KYNLFSVSNHYGGLDG 1065
Query: 283 GHYCVYIRSAVDGKWFCFNDSNICLVSWEDIQ 314
GHY Y ++A +WF F+D + +S ++
Sbjct: 1066 GHYTAYCKNAARQRWFKFDDHEVSDISVSSVK 1097
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 88.6 bits (218), Expect = 7e-18
Identities = 75/332 (22%), Positives = 139/332 (41%), Gaps = 47/332 (14%)
Query: 20 LVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQ-----RRSVPFQMLLLLE 74
L GL N+G TC +NS++Q A R + + V + ++++
Sbjct: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
Query: 75 KMQDSRQKAVWPLELAYCLQKYNVPL--FVQHDAAQLYLKLWNLI--------------- 117
+ + + + P + + K N + Q D+ +L L L + +
Sbjct: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895
Query: 118 --KDQIADVHLVER------------LQALYMIRVKDSLICLDCAMESSRNSSMLTLRLS 163
D + D E + AL+ + K ++ CL C +S + + L L
Sbjct: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955
Query: 164 FFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLM 223
+ S TL+D L F + +L+ ++ +C +C + + +++ LP L +HL
Sbjct: 956 ---LASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLK 1012
Query: 224 RFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADS 282
RFS +K+ S+ FP ++LD SQ + + + +Y LF+V H G D
Sbjct: 1013 RFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLK-------KYNLFSVSNHYGGLDG 1065
Query: 283 GHYCVYIRSAVDGKWFCFNDSNICLVSWEDIQ 314
GHY Y ++A +WF F+D + +S ++
Sbjct: 1066 GHYTAYCKNAARQRWFKFDDHEVSDISVSSVK 1097
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 88.6 bits (218), Expect = 7e-18
Identities = 75/332 (22%), Positives = 139/332 (41%), Gaps = 47/332 (14%)
Query: 20 LVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQ-----RRSVPFQMLLLLE 74
L GL N+G TC +NS++Q A R + + V + ++++
Sbjct: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
Query: 75 KMQDSRQKAVWPLELAYCLQKYNVPL--FVQHDAAQLYLKLWNLI--------------- 117
+ + + + P + + K N + Q D+ +L L L + +
Sbjct: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895
Query: 118 --KDQIADVHLVER------------LQALYMIRVKDSLICLDCAMESSRNSSMLTLRLS 163
D + D E + AL+ + K ++ CL C +S + + L L
Sbjct: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955
Query: 164 FFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLM 223
+ S TL+D L F + +L+ ++ +C +C + + +++ LP L +HL
Sbjct: 956 ---LASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLK 1012
Query: 224 RFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADS 282
RFS +K+ S+ FP ++LD SQ + + + +Y LF+V H G D
Sbjct: 1013 RFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLK-------KYNLFSVSNHYGGLDG 1065
Query: 283 GHYCVYIRSAVDGKWFCFNDSNICLVSWEDIQ 314
GHY Y ++A +WF F+D + +S ++
Sbjct: 1066 GHYTAYCKNAARQRWFKFDDHEVSDISVSSVK 1097
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 85.1 bits (209), Expect = 8e-17
Identities = 86/334 (25%), Positives = 133/334 (39%), Gaps = 49/334 (14%)
Query: 19 GLVGLHNIGQTCCLNSLIQVF-----VMNVDFARILKRITVPRGADEQRRSVPFQMLLLL 73
GL GL N+G TC +NS++Q + + R+ R + G++ V L+
Sbjct: 56 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMR-DLHHGSNAHTALVEEFAKLIQ 114
Query: 74 EKMQDSRQKAVWPLELAYCLQKYNVPLFV---QHDAAQLYLKLWNLIKDQIADV------ 124
S V P E +Q+Y P FV Q DA + L + + +++ V
Sbjct: 115 TIWTSSPNDVVSPSEFKTQIQRY-APRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKS 173
Query: 125 ------HLVE-----------------RLQALYMIRVKDSLICLDCAMESSRNSSMLTLR 161
HL + R+ L++ ++K SL C DC S+ L
Sbjct: 174 NPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLS 233
Query: 162 LSFFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIH 221
L P TL D + F + L K C C + R + + P+ L +H
Sbjct: 234 LPIAK-RGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLH 292
Query: 222 LMRFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMA 280
L RFS +T K+ + FP + LD + +E + Y L+AV H G
Sbjct: 293 LKRFSESRIRTSKLTTFVNFPLRDLDLREFA--------SENTNHAVYNLYAVSNHSGTT 344
Query: 281 DSGHYCVYIRSAVDGKWFCFNDSNICLVSWEDIQ 314
GHY Y RS G+W FNDS++ +S ++
Sbjct: 345 MGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVR 378
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 85.1 bits (209), Expect = 8e-17
Identities = 86/334 (25%), Positives = 133/334 (39%), Gaps = 49/334 (14%)
Query: 19 GLVGLHNIGQTCCLNSLIQVF-----VMNVDFARILKRITVPRGADEQRRSVPFQMLLLL 73
GL GL N+G TC +NS++Q + + R+ R + G++ V L+
Sbjct: 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMR-DLHHGSNAHTALVEEFAKLIQ 323
Query: 74 EKMQDSRQKAVWPLELAYCLQKYNVPLFV---QHDAAQLYLKLWNLIKDQIADV------ 124
S V P E +Q+Y P FV Q DA + L + + +++ V
Sbjct: 324 TIWTSSPNDVVSPSEFKTQIQRY-APRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKS 382
Query: 125 ------HLVE-----------------RLQALYMIRVKDSLICLDCAMESSRNSSMLTLR 161
HL + R+ L++ ++K SL C DC S+ L
Sbjct: 383 NPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLS 442
Query: 162 LSFFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIH 221
L P TL D + F + L K C C + R + + P+ L +H
Sbjct: 443 LPIAK-RGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLH 501
Query: 222 LMRFSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMA 280
L RFS +T K+ + FP + LD + +E + Y L+AV H G
Sbjct: 502 LKRFSESRIRTSKLTTFVNFPLRDLDLREFA--------SENTNHAVYNLYAVSNHSGTT 553
Query: 281 DSGHYCVYIRSAVDGKWFCFNDSNICLVSWEDIQ 314
GHY Y RS G+W FNDS++ +S ++
Sbjct: 554 MGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVR 587
>gi|110347427 ubiquitin specific protease 34 [Homo sapiens]
Length = 3546
Score = 84.7 bits (208), Expect = 1e-16
Identities = 73/307 (23%), Positives = 127/307 (41%), Gaps = 31/307 (10%)
Query: 21 VGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLLLEKMQDSR 80
VGL N+G TC L S IQ M + + + T D + ++ ++ + + +S
Sbjct: 1894 VGLTNLGATCYLASTIQQLYMIPEARQAV--FTAKYSEDMKHKTTLLELQKMFTYLMESE 1951
Query: 81 QKAVWPLELA--YCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERLQALYMIRV 138
KA P Y + K + Q D + + L I++ + L +++L+ +
Sbjct: 1952 CKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPE--LKNTVKSLFGGVI 2009
Query: 139 KDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCEN 198
++++ LDC S T+R D +K + ++L L + C +
Sbjct: 2010 TNNVVSLDCEHVSQTAEEFYTVRCQVAD-----MKNIYESLDEVTIKDTLEGDNMYTCSH 2064
Query: 199 CGKKTRGKQVLKLTHLPQTLTIHLMR--FSIRNSQTRKICHSLYFPQSLDFSQILP---- 252
CGKK R ++ LP+ L+ + MR F++ K+ FP LD +
Sbjct: 2065 CGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLM 2124
Query: 253 --------MKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRSAV------DGKWF 298
K S +++ +Y+L V H G AD GHY +IR V + KW+
Sbjct: 2125 GKSERKEGFKEVSDHSKDSESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWY 2184
Query: 299 CFNDSNI 305
FND+ +
Sbjct: 2185 LFNDAEV 2191
>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 84.3 bits (207), Expect = 1e-16
Identities = 50/148 (33%), Positives = 74/148 (50%), Gaps = 5/148 (3%)
Query: 171 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 230
P+ TLED L FF EL + CE C K G + K+ LP+ L IHL RF
Sbjct: 535 PVVTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVM 594
Query: 231 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 290
+ KI + FP L+ + P + C ++ + Y+L +VI H G A SGHY Y +
Sbjct: 595 YSFKINSHVSFP--LEGLDLRPFLAKECTSQITT---YDLLSVICHHGTAGSGHYIAYCQ 649
Query: 291 SAVDGKWFCFNDSNICLVSWEDIQCTYG 318
+ ++G+W+ F+D + V +Q G
Sbjct: 650 NVINGQWYEFDDQYVTEVHETVVQNAEG 677
>gi|183397136 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 84.3 bits (207), Expect = 1e-16
Identities = 50/148 (33%), Positives = 74/148 (50%), Gaps = 5/148 (3%)
Query: 171 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 230
P+ TLED L FF EL + CE C K G + K+ LP+ L IHL RF
Sbjct: 535 PVVTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVM 594
Query: 231 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 290
+ KI + FP L+ + P + C ++ + Y+L +VI H G A SGHY Y +
Sbjct: 595 YSFKINSHVSFP--LEGLDLRPFLAKECTSQITT---YDLLSVICHHGTAGSGHYIAYCQ 649
Query: 291 SAVDGKWFCFNDSNICLVSWEDIQCTYG 318
+ ++G+W+ F+D + V +Q G
Sbjct: 650 NVINGQWYEFDDQYVTEVHETVVQNAEG 677
>gi|183397134 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 84.3 bits (207), Expect = 1e-16
Identities = 50/148 (33%), Positives = 74/148 (50%), Gaps = 5/148 (3%)
Query: 171 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 230
P+ TLED L FF EL + CE C K G + K+ LP+ L IHL RF
Sbjct: 535 PVVTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVM 594
Query: 231 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 290
+ KI + FP L+ + P + C ++ + Y+L +VI H G A SGHY Y +
Sbjct: 595 YSFKINSHVSFP--LEGLDLRPFLAKECTSQITT---YDLLSVICHHGTAGSGHYIAYCQ 649
Query: 291 SAVDGKWFCFNDSNICLVSWEDIQCTYG 318
+ ++G+W+ F+D + V +Q G
Sbjct: 650 NVINGQWYEFDDQYVTEVHETVVQNAEG 677
>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
Length = 828
Score = 79.7 bits (195), Expect = 3e-15
Identities = 48/144 (33%), Positives = 72/144 (50%), Gaps = 5/144 (3%)
Query: 171 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 230
P+ TL+D L FF EL + CE C K G + K+ + P+ L IHL RF
Sbjct: 557 PVVTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELM 616
Query: 231 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 290
+ KI + FP L+ + P + A+ + Y+L +VI H G A SGHY Y R
Sbjct: 617 FSTKISTHVSFP--LEGLDLQPFLAKDSPAQIVT---YDLLSVICHHGTASSGHYIAYCR 671
Query: 291 SAVDGKWFCFNDSNICLVSWEDIQ 314
+ ++ W+ F+D ++ VS +Q
Sbjct: 672 NNLNNLWYEFDDQSVTEVSESTVQ 695
Score = 31.6 bits (70), Expect = 1.1
Identities = 25/107 (23%), Positives = 44/107 (41%), Gaps = 2/107 (1%)
Query: 19 GLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLLLEKMQD 78
GL GL NIG TC +N+ +Q + D++ + L+ E
Sbjct: 183 GLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAICKSYLKLMTELWHK 242
Query: 79 SRQKAVWPLELAYCLQKYNVPL--FVQHDAAQLYLKLWNLIKDQIAD 123
SR +V P L ++ N + Q DA + L +L+ +++ +
Sbjct: 243 SRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE 289
>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
Length = 942
Score = 79.7 bits (195), Expect = 3e-15
Identities = 48/144 (33%), Positives = 72/144 (50%), Gaps = 5/144 (3%)
Query: 171 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 230
P+ TL+D L FF EL + CE C K G + K+ + P+ L IHL RF
Sbjct: 565 PVVTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELM 624
Query: 231 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 290
+ KI + FP L+ + P + A+ + Y+L +VI H G A SGHY Y R
Sbjct: 625 FSTKISTHVSFP--LEGLDLQPFLAKDSPAQIVT---YDLLSVICHHGTASSGHYIAYCR 679
Query: 291 SAVDGKWFCFNDSNICLVSWEDIQ 314
+ ++ W+ F+D ++ VS +Q
Sbjct: 680 NNLNNLWYEFDDQSVTEVSESTVQ 703
Score = 31.6 bits (70), Expect = 1.1
Identities = 25/107 (23%), Positives = 44/107 (41%), Gaps = 2/107 (1%)
Query: 19 GLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLLLEKMQD 78
GL GL NIG TC +N+ +Q + D++ + L+ E
Sbjct: 183 GLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAICKSYLKLMTELWHK 242
Query: 79 SRQKAVWPLELAYCLQKYNVPL--FVQHDAAQLYLKLWNLIKDQIAD 123
SR +V P L ++ N + Q DA + L +L+ +++ +
Sbjct: 243 SRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE 289
>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
Length = 911
Score = 79.7 bits (195), Expect = 3e-15
Identities = 48/144 (33%), Positives = 72/144 (50%), Gaps = 5/144 (3%)
Query: 171 PLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNS 230
P+ TL+D L FF EL + CE C K G + K+ + P+ L IHL RF
Sbjct: 534 PVVTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELM 593
Query: 231 QTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIR 290
+ KI + FP L+ + P + A+ + Y+L +VI H G A SGHY Y R
Sbjct: 594 FSTKISTHVSFP--LEGLDLQPFLAKDSPAQIVT---YDLLSVICHHGTASSGHYIAYCR 648
Query: 291 SAVDGKWFCFNDSNICLVSWEDIQ 314
+ ++ W+ F+D ++ VS +Q
Sbjct: 649 NNLNNLWYEFDDQSVTEVSESTVQ 672
Score = 31.6 bits (70), Expect = 1.1
Identities = 25/107 (23%), Positives = 44/107 (41%), Gaps = 2/107 (1%)
Query: 19 GLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLLLEKMQD 78
GL GL NIG TC +N+ +Q + D++ + L+ E
Sbjct: 152 GLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAICKSYLKLMTELWHK 211
Query: 79 SRQKAVWPLELAYCLQKYNVPL--FVQHDAAQLYLKLWNLIKDQIAD 123
SR +V P L ++ N + Q DA + L +L+ +++ +
Sbjct: 212 SRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE 258
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 79.7 bits (195), Expect = 3e-15
Identities = 52/154 (33%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 172 LKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQ 231
+ +L D L F +P L S +K C +C + L + LP HL RF Q
Sbjct: 546 IPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKLPIVACFHLKRFEHVGKQ 605
Query: 232 TRKICHSLYFPQSLDFSQILPMKRESCDAEEQ-------SGGQYELFAVIAHVGMADSGH 284
RKI + FP LD + L +ES E Q + +Y LFAVI H G +SGH
Sbjct: 606 RRKINTFISFPLELDMTPFLASTKESRMKEGQPPTDCVPNENKYSLFAVINHHGTLESGH 665
Query: 285 YCVYIRSAVDGKWFCFNDSNICLVSWEDIQCTYG 318
Y +IR D +WF +D+ I + ED+ + G
Sbjct: 666 YTSFIRQQKD-QWFSCDDAIITKATIEDLLYSEG 698
>gi|41055953 ubiquitin thioesterase 40 [Homo sapiens]
Length = 1247
Score = 77.0 bits (188), Expect = 2e-14
Identities = 77/310 (24%), Positives = 127/310 (40%), Gaps = 28/310 (9%)
Query: 20 LVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPR--------GADEQRRSVPFQMLL 71
L G+ N G TC LNSL+Q +F L + D + R +P Q+
Sbjct: 52 LSGIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGLFEDKDKPDAKVRIIPLQLQR 111
Query: 72 LLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERLQ 131
L ++ Q+A +L + QHD +L L++ ++ + + +
Sbjct: 112 LFAQLLLLDQEAASTADLTDSFGWTSNEEMRQHDVQELNRILFSALETSLVGTSGHDLIY 171
Query: 132 ALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDVDSKPLKTLEDALHCFFQPRELSSK 191
LY + + ++C +C S R L L ++ +V LEDAL + E+
Sbjct: 172 RLYHGTIVNQIVCKECKNVSERQEDFLDLTVAVKNVSG-----LEDALWNMYVEEEVFDC 226
Query: 192 SKCF-CENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIR--NSQTRKICHSLYFPQSLDFS 248
+ C C + + + KL LP LT+ L+RF+ + K FP ++
Sbjct: 227 DNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLK 286
Query: 249 QILPMKRESCDAEEQSGGQY--ELFAVIAHVGMADSGHYCVYIRSAVD--GKWFCFNDSN 304
C+ E +Y +LF+VI H G GHY VYI+ VD G W + +
Sbjct: 287 PF-------CEQSELDDLEYIYDLFSVIIHKGGCYGGHYHVYIKD-VDHLGNWQFQEEKS 338
Query: 305 ICLVSWEDIQ 314
V+ +D+Q
Sbjct: 339 KPDVNLKDLQ 348
>gi|45267835 ubiquitin specific protease 50 [Homo sapiens]
Length = 339
Score = 75.9 bits (185), Expect = 5e-14
Identities = 69/310 (22%), Positives = 125/310 (40%), Gaps = 50/310 (16%)
Query: 19 GLVGLHNIGQTCCLNSLIQV---------FVMNVDFARILKRITVPRGADEQRRSVPFQM 69
G+ GL N+G TCC+N++ Q + + + L++ +P E + +
Sbjct: 42 GVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAY-- 99
Query: 70 LLLLEKMQDSRQKAVWPLELAYCLQKYNVPLF---VQHDAAQLYLKLWNLIKDQIADVHL 126
L+ M V P E+ + P F +Q DA + + + N + + + H
Sbjct: 100 --LMTDMWLGDSDCVSP-EIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHY 156
Query: 127 VER----------------------LQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSF 164
R + L+ ++ S++CL C + +N L
Sbjct: 157 SRRRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLP- 215
Query: 165 FDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMR 224
+ SK +L D L CFFQ L+ ++ C C K ++ P+ + HL R
Sbjct: 216 --IPSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKR 273
Query: 225 FSIRNSQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSG 283
F I+ + RK+ +++P +LD + + C + +Y L AV+ H G D G
Sbjct: 274 FDIQGTTKRKLRTDIHYPLTNLDLTPYI------CSIFRKY-PKYNLCAVVNHFGDLDGG 326
Query: 284 HYCVYIRSAV 293
HY + +++V
Sbjct: 327 HYTAFCKNSV 336
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 75.5 bits (184), Expect = 7e-14
Identities = 49/150 (32%), Positives = 68/150 (45%), Gaps = 9/150 (6%)
Query: 172 LKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQ 231
+ TL D L F +P L S +K C +C + L + LP H RF Q
Sbjct: 260 ITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFEHSAKQ 319
Query: 232 TRKICHSLYFPQSLDFSQILPMKRES-----CDAEEQSG---GQYELFAVIAHVGMADSG 283
RKI + FP LD + + +ES SG +Y LFAV+ H G +SG
Sbjct: 320 RRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQGTLESG 379
Query: 284 HYCVYIRSAVDGKWFCFNDSNICLVSWEDI 313
HY +IR D +WF +D+ I S +D+
Sbjct: 380 HYTSFIRHHKD-QWFKCDDAVITKASIKDV 408
>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
Length = 952
Score = 73.9 bits (180), Expect = 2e-13
Identities = 45/146 (30%), Positives = 68/146 (46%), Gaps = 10/146 (6%)
Query: 170 KPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRN 229
KP L+D + F +L ++ +C NC + + + L L LP L +HL RFS
Sbjct: 754 KPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSR 813
Query: 230 SQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGG-QYELFAVIAHVGMADSGHYCV 287
K+ + FP LD S+ L +G +Y L AV H G GHY
Sbjct: 814 YMRDKLDTLVDFPINDLDMSEFL--------INPNAGPCRYNLIAVSNHYGGMGGGHYTA 865
Query: 288 YIRSAVDGKWFCFNDSNICLVSWEDI 313
+ ++ DGKW+ F+DS++ S + I
Sbjct: 866 FAKNKDDGKWYYFDDSSVSTASEDQI 891
Score = 29.3 bits (64), Expect = 5.4
Identities = 12/19 (63%), Positives = 14/19 (73%)
Query: 19 GLVGLHNIGQTCCLNSLIQ 37
GL GL N+G TC +NS IQ
Sbjct: 258 GLCGLSNLGNTCFMNSAIQ 276
>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
Length = 1352
Score = 73.6 bits (179), Expect = 2e-13
Identities = 48/180 (26%), Positives = 78/180 (43%), Gaps = 16/180 (8%)
Query: 174 TLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR 233
TL + + L+ C +C + +G L L LP L IHL RF +
Sbjct: 597 TLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQEGDRRM 656
Query: 234 KICHSLYFPQS-LDF---------------SQILPMKRESCDAEEQSGGQYELFAVIAHV 277
K+ + + FP + LD S P +R + Y+L+AV H
Sbjct: 657 KLQNMVKFPLTGLDMTPHVVKRSQSSWSLPSHWSPWRRPYGLGRDPEDYIYDLYAVCNHH 716
Query: 278 GMADSGHYCVYIRSAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWXETDLGNWSLMSS 337
G GHY Y +++VDG W+CF+DS++ +S +++ ++ T + +WS SS
Sbjct: 717 GTMQGGHYTAYCKNSVDGLWYCFDDSDVQQLSEDEVCTQTAYILFYQRRTAIPSWSANSS 776
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 73.2 bits (178), Expect = 3e-13
Identities = 48/148 (32%), Positives = 68/148 (45%), Gaps = 9/148 (6%)
Query: 174 TLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR 233
TL D L F +P L S +K C C + L + LP HL RF R
Sbjct: 361 TLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRR 420
Query: 234 KICHSLYFPQSLDFSQILPMKRES-CDAEEQ-------SGGQYELFAVIAHVGMADSGHY 285
KI + FP LD + + +ES + + Q + +Y LFAV+ H G +SGHY
Sbjct: 421 KITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGTLESGHY 480
Query: 286 CVYIRSAVDGKWFCFNDSNICLVSWEDI 313
+IR D +WF +D+ I S +D+
Sbjct: 481 TSFIRQHKD-QWFKCDDAIITKASIKDV 507
>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
Length = 963
Score = 72.0 bits (175), Expect = 7e-13
Identities = 44/145 (30%), Positives = 67/145 (46%), Gaps = 8/145 (5%)
Query: 170 KPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRN 229
K L D + F L +C NC K + + L LP+ L +HL RFS
Sbjct: 773 KTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNR 832
Query: 230 SQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVY 288
K+ + FP + L+ S+ + C+ + Y+L AV H G GHY Y
Sbjct: 833 YWRDKLDTVVEFPIRGLNMSEFV------CNLSARPY-VYDLIAVSNHYGAMGVGHYTAY 885
Query: 289 IRSAVDGKWFCFNDSNICLVSWEDI 313
++ ++GKW+ F+DSN+ L S + I
Sbjct: 886 AKNKLNGKWYYFDDSNVSLASEDQI 910
>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
Length = 916
Score = 72.0 bits (175), Expect = 7e-13
Identities = 44/145 (30%), Positives = 67/145 (46%), Gaps = 8/145 (5%)
Query: 170 KPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRN 229
K L D + F L +C NC K + + L LP+ L +HL RFS
Sbjct: 726 KTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNR 785
Query: 230 SQTRKICHSLYFP-QSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVY 288
K+ + FP + L+ S+ + C+ + Y+L AV H G GHY Y
Sbjct: 786 YWRDKLDTVVEFPIRGLNMSEFV------CNLSARPY-VYDLIAVSNHYGAMGVGHYTAY 838
Query: 289 IRSAVDGKWFCFNDSNICLVSWEDI 313
++ ++GKW+ F+DSN+ L S + I
Sbjct: 839 AKNKLNGKWYYFDDSNVSLASEDQI 863
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.137 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,514,295
Number of Sequences: 37866
Number of extensions: 517871
Number of successful extensions: 1820
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 1552
Number of HSP's gapped (non-prelim): 202
length of query: 344
length of database: 18,247,518
effective HSP length: 103
effective length of query: 241
effective length of database: 14,347,320
effective search space: 3457704120
effective search space used: 3457704120
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.