Guide to the Human Genome
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Search of human proteins with 119392094

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]
         (993 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]      1946   0.0  
gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]        182   1e-45
gi|122937299 DNA replication helicase 2 homolog [Homo sapiens]        171   3e-42
gi|113722133 senataxin [Homo sapiens]                                 150   4e-36
gi|14251207 MOV10-like 1 [Homo sapiens]                               123   7e-28
gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sap...   115   2e-25
gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapi...   115   2e-25
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ...   115   2e-25
gi|156105695 PPAR-alpha interacting complex protein 285 isoform ...   115   2e-25
gi|54792138 helicase with zinc finger domain [Homo sapiens]            86   2e-16
gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]         85   4e-16
gi|38788372 aquarius [Homo sapiens]                                    71   6e-12
gi|38505213 YTH domain containing 2 [Homo sapiens]                     43   0.001
gi|157266334 tubby like protein 1 [Homo sapiens]                       43   0.002
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         42   0.002
gi|153792074 proline rich 12 [Homo sapiens]                            42   0.003
gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]     42   0.004
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    41   0.006
gi|21359918 zinc finger, AN1-type domain 6 [Homo sapiens]              40   0.011
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]    40   0.011
gi|239753786 PREDICTED: hypothetical protein LOC100129786 [Homo ...    40   0.014
gi|169167301 PREDICTED: hypothetical protein LOC100129786 [Homo ...    40   0.014
gi|169166477 PREDICTED: hypothetical protein LOC100129786 [Homo ...    40   0.014
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]            40   0.014
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    40   0.014
gi|21361684 G patch domain containing 1 [Homo sapiens]                 40   0.014
gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]       39   0.019
gi|150378549 tangerin [Homo sapiens]                                   39   0.019
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ...    39   0.019
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap...    39   0.024

>gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]
          Length = 993

 Score = 1946 bits (5042), Expect = 0.0
 Identities = 993/993 (100%), Positives = 993/993 (100%)

Query: 1   MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLY 60
           MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLY
Sbjct: 1   MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLY 60

Query: 61  GRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDE 120
           GRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDE
Sbjct: 61  GRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDE 120

Query: 121 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS 180
           SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS
Sbjct: 121 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS 180

Query: 181 EIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC 240
           EIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC
Sbjct: 181 EIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC 240

Query: 241 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI 300
           CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI
Sbjct: 241 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI 300

Query: 301 DQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGP 360
           DQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGP
Sbjct: 301 DQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGP 360

Query: 361 LKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSL 420
           LKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSL
Sbjct: 361 LKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSL 420

Query: 421 SLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAA 480
           SLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAA
Sbjct: 421 SLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAA 480

Query: 481 TEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSP 540
           TEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSP
Sbjct: 481 TEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSP 540

Query: 541 YNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVA 600
           YNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVA
Sbjct: 541 YNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVA 600

Query: 601 VTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSS 660
           VTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSS
Sbjct: 601 VTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSS 660

Query: 661 HAATKPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGV 720
           HAATKPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGV
Sbjct: 661 HAATKPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGV 720

Query: 721 ESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFI 780
           ESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFI
Sbjct: 721 ESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFI 780

Query: 781 TVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQR 840
           TVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQR
Sbjct: 781 TVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQR 840

Query: 841 VRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFA 900
           VRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFA
Sbjct: 841 VRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFA 900

Query: 901 KCTAGVTTLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGS 960
           KCTAGVTTLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGS
Sbjct: 901 KCTAGVTTLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGS 960

Query: 961 LDPAKRAQLQRRLDKKLSELSNQRTSRRKERGT 993
           LDPAKRAQLQRRLDKKLSELSNQRTSRRKERGT
Sbjct: 961 LDPAKRAQLQRRLDKKLSELSNQRTSRRKERGT 993


>gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]
          Length = 1118

 Score =  182 bits (463), Expect = 1e-45
 Identities = 154/454 (33%), Positives = 221/454 (48%), Gaps = 43/454 (9%)

Query: 192 LDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGL-KVLCCAPSNIAVDN 250
           L+ SQ  AV   L Q+ L++I GPPGTGKT T   I+    +QG   VL CAPSNIAVD 
Sbjct: 471 LNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQ 529

Query: 251 LVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDIDQVFVKNKKT 310
           L E++     +++RL   +R          +A+ +      +   IR ++D +    K  
Sbjct: 530 LTEKIHQTGLKVVRLCAKSR----------EAIDSPVSFLALHNQIR-NMDSMPELQKLQ 578

Query: 311 QDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGPLKLLPESYFD 370
           Q K E     +  +   + LK   E    E L +A+V+  T  GA      K+     F 
Sbjct: 579 QLKDETGELSSADEKRYRALKRTAER---ELLMNADVICCTCVGAGDPRLAKM----QFR 631

Query: 371 VVVIDECAQALEASCWIPL-LKARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEE 429
            ++IDE  QA E  C +P+ L A++ IL GDH QL P  +  KAA AGLS SL ERL   
Sbjct: 632 SILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVV- 690

Query: 430 YGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLL 489
            G R +R L VQYRMH A+  + S+  Y G L    + A  + +         +   P+ 
Sbjct: 691 LGIRPIR-LQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFD--FQWPQPDKPMF 747

Query: 490 LVDTAGCGLFELEEEDEQSKG----NPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQV 545
              T G       +E+  S G    N  E   V      L+ AG     I +++PY  Q 
Sbjct: 748 FYVTQG-------QEEIASSGTSYLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQR 800

Query: 546 DLLRQSL-------VHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRIN 598
             L Q +          + E+EI SVD FQGREK+ +ILS VR+N    +GFL + RR+N
Sbjct: 801 SYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLN 860

Query: 599 VAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQ 632
           VA+TRAR  V ++ + + ++       L+ Y+ +
Sbjct: 861 VALTRARYGVIIVGNPKALSKQPLWNHLLNYYKE 894


>gi|122937299 DNA replication helicase 2 homolog [Homo sapiens]
          Length = 1146

 Score =  171 bits (433), Expect = 3e-42
 Identities = 172/651 (26%), Positives = 288/651 (44%), Gaps = 102/651 (15%)

Query: 17   LELERDAEVEERRSWQENISL---KELQSRGVCLLKL-QVSSQRTGLYGRLLVTFEPRRY 72
            L L  +++ ++ +   +NI L    E++  G C+  L ++   +    G+ L  F+ +  
Sbjct: 532  LMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKH- 590

Query: 73   GSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFD-------ESHDFQ 125
                A+P  +  +GD V +         L+ G +  +   +VT   D       ES  F+
Sbjct: 591  ---GAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFR 647

Query: 126  LSLDRENSY------RLLKLA-NDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSP 178
            L  + +N         L KL  N    ++L+  +I  ++         I  L   S+  P
Sbjct: 648  LDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFRE------PQFISYL---SSVLP 698

Query: 179  ASEIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKV 238
                  +      L+  Q++A+   L  K+  +I G PGTGKTTT+  ++      G  V
Sbjct: 699  HDAKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSV 758

Query: 239  LCCAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRK 298
            L  + ++ AVDN++ +LA  K   LRLG   ++  +IQQ                     
Sbjct: 759  LLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQ--------------------- 797

Query: 299  DIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASAD 358
                 F + +  + K  KS                   A+LE L ++ +++AT T    +
Sbjct: 798  -----FTEQEICRSKSIKS------------------LALLEELYNSQLIVAT-TCMGIN 833

Query: 359  GPLKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGL 418
             P+       FD  ++DE +Q  +  C  PL  +R+ +L GDH+QLPP  ++ +A   G+
Sbjct: 834  HPI--FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGM 891

Query: 419  SLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVA-------RHL 471
            S SL +RL +   A V   LTVQYRM+  IM  ++   Y G+L   S          RH 
Sbjct: 892  SESLFKRLEQNKSAVV--QLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHF 949

Query: 472  ------------LRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVS 519
                          D P +    E   P+  ++T      E  E+   S  N  E +L+ 
Sbjct: 950  KDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVS--NVTEAKLIV 1007

Query: 520  LHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSF 579
                  V AG    DI +++PY  Q+ ++   L      +E+ +VD +QGR+K  V++SF
Sbjct: 1008 FLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSF 1067

Query: 580  VRSNRKGEVGFLAED-RRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEY 629
            VRSN+ G VG L +D RR+NVA+TRA+  + ++    ++N +  L+ L+ +
Sbjct: 1068 VRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNH 1118


>gi|113722133 senataxin [Homo sapiens]
          Length = 2677

 Score =  150 bits (380), Expect = 4e-36
 Identities = 155/604 (25%), Positives = 260/604 (43%), Gaps = 119/604 (19%)

Query: 205  SQKELAIIHGPPGTGKTTTVVEIILQAVKQGLK----------------VLCCAPSNIAV 248
            S  ++ +IHGPPGTGK+ T+V ++ + + +  +                VL CAPSN AV
Sbjct: 1954 SVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAV 2013

Query: 249  DNLVERLAL-----CKQR-----------ILRLGHPARLLESIQQHSLDAVLARSDSAQI 292
            D L++++ L     CK +           ++RLG    +   + + SLD+ +      ++
Sbjct: 2014 DELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNHRMKKEL 2073

Query: 293  VADIRKDIDQVFVKNKKTQD------KREKSNFRNEIKLLRKEL--------KEREEAA- 337
             + +     Q   K K+  D       R+++  R   ++ R+EL        KER+E A 
Sbjct: 2074 PSHV-----QAMHKRKEFLDYQLDELSRQRALCRGGREIQRQELDENISKVSKERQELAS 2128

Query: 338  ----------------MLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQAL 381
                            +LES       L+T+ G   +   +      F  V++DE  Q+ 
Sbjct: 2129 KIKEVQGRPQKTQSIIILESHIIC-CTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSC 2187

Query: 382  EASCWIPLL-KARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARV------ 434
            E     PL+ +  K IL GD KQLPPT +S KA   G   S+M R        V      
Sbjct: 2188 EIETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMIS 2247

Query: 435  ---VRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLLLV 491
               +  LTVQYRMH  I  + S+ +Y   L  +        R    +  + +      LV
Sbjct: 2248 RLPILQLTVQYRMHPDICLFPSNYVYNRNLKTN--------RQTEAIRCSSDWPFQPYLV 2299

Query: 492  DTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVD--AGVPARDIAVVSPYNLQVDLLR 549
               G G    E  D  S  N  E++LV   I+ + D    V  R+I +++ Y  Q  +++
Sbjct: 2300 FDVGDG---SERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKAQKTMIQ 2356

Query: 550  QSL---VHRHPELEIKSVDGFQGREKEAVILSFVRSNR-KGEVGFLAEDRRINVAVTRAR 605
            + L     R    E+ +VD FQGR+K+ VI++ VR+N  +G +GFLA  +R+NV +TRA+
Sbjct: 2357 KDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAK 2416

Query: 606  RHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHEN---------- 655
              + ++   RT+  +     L++   + G +    +       +NY H+           
Sbjct: 2417 YSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCD-------KNYRHDAVKILKLKPVL 2469

Query: 656  SQGSSHAAT------KPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQ 709
             +  +H  T      +PQG   S++  S   +    A+        K    ++ S+ P +
Sbjct: 2470 QRSLTHPPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPER 2529

Query: 710  PSLN 713
            P ++
Sbjct: 2530 PPVH 2533


>gi|14251207 MOV10-like 1 [Homo sapiens]
          Length = 1211

 Score =  123 bits (309), Expect = 7e-28
 Identities = 146/531 (27%), Positives = 222/531 (41%), Gaps = 94/531 (17%)

Query: 185  LTFFNTCLDTSQKEAVLFALS---QKELAIIHGPPGTGKTTTVVEIILQA--VKQGLKVL 239
            + FFN  L+ +QK AV   LS   +    I+ GPPGTGKT T++E +LQ        ++L
Sbjct: 738  MEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFALPDSRIL 797

Query: 240  CCAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKD 299
             CAPSN A D +  RL           H +++L   Q  ++  V A     +IV      
Sbjct: 798  VCAPSNSAADLVCLRL-----------HESKVL---QPATMVRVNATCRFEEIV------ 837

Query: 300  IDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADG 359
            ID V    +  +D  + S FR  I                   T ++  L    G     
Sbjct: 838  IDAVKPYCRDGEDIWKASRFRIIIT------------------TCSSSGLFYQIGVRV-- 877

Query: 360  PLKLLPESYFDVVVIDECAQALEASCWIPLLK----ARKCILAGDHKQLPPTTVSHKAAL 415
                    +F  V +DE  QA E  C IPL      + + +LAGD  QL P   S  A  
Sbjct: 878  -------GHFTHVFVDEAGQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMA 930

Query: 416  AGLSLSLMERLAEE---------YGA------RVVRTLTVQYRMHQAIMRWASDTMYLGQ 460
             GL++S +ERL            +GA       +V  L   YR H+A++   S   Y  +
Sbjct: 931  YGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRE 990

Query: 461  LTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSL 520
            L   +     ++  L G     + G PL+     G    E  E    S  NP E   V  
Sbjct: 991  LEVCADPT--VVTSLLGWEKLPKKGFPLIFHGVRGS---EAREGKSPSWFNPAEAVQVLR 1045

Query: 521  HIQAL---VDAGVPARDIAVVSPYNLQVDLLRQSLVHRH-PELEIKSVDGFQGREKEAVI 576
            +   L   + + V A DI V++PY  QV+ +R  L +    ++++ SV+ FQG+E   +I
Sbjct: 1046 YCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRNVDLMDIKVGSVEEFQGQEYLVII 1105

Query: 577  LSFVRSNR------KGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYF 630
            +S VRSN       +  +GFL+  +R NVA+TR +  + V+ +   +        L+EY 
Sbjct: 1106 ISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYS 1165

Query: 631  TQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQGPATSTRTGSQRQE 681
              +G          D+ P   + ++ Q        P  P     TG ++ +
Sbjct: 1166 ITNGVYMGC-----DLPP---ALQSLQNCGEGVADPSYPVVPESTGPEKHQ 1208


>gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo
           sapiens]
          Length = 1003

 Score =  115 bits (289), Expect = 2e-25
 Identities = 122/470 (25%), Positives = 191/470 (40%), Gaps = 94/470 (20%)

Query: 211 IIHGPPGTGKTTTVVEIILQAVKQGLK--VLCCAPSNIAVDNLVERLAL-CKQRILRLGH 267
           II GPPGTGKT T+VE I Q VK   K  +L CAPSN   D L +RL +     I RL  
Sbjct: 521 IIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLA 580

Query: 268 PARLLESIQQHSLDAVLARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLR 327
           P+R          D  +   D         K  + VF   KK Q+ R             
Sbjct: 581 PSR----------DIRMVPEDIKPCCNWDAKKGEYVFPAKKKLQEYR------------- 617

Query: 328 KELKEREEAAMLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWI 387
                     ++ +L +A  +++              P  +F  + IDE    +E    +
Sbjct: 618 ---------VLITTLITAGRLVSAQ-----------FPIDHFTHIFIDEAGHCMEPESLV 657

Query: 388 PLL----------KARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLA---------- 427
            +              + +LAGD +QL P   S      GL  SL+ERL           
Sbjct: 658 AIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGP 717

Query: 428 EEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVP 487
           + Y  + +  L   YR H  I+   +   Y G+L A + V           A     G P
Sbjct: 718 DGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDR--ERFCRWAGLPRQGFP 775

Query: 488 LLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALV-------DAGVPARDIAVVSP 540
           ++     G    +  E +  S  NP E   V+ +++ L+        A +  R + V+SP
Sbjct: 776 IIFHGVMGK---DEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISP 832

Query: 541 YNLQVDLLRQSLVHRHPEL---------EIKSVDGFQGREKEAVILSFVRSNRKG----- 586
           Y  QV+ +R  +     EL         ++ SV+ FQG+E+  +++S VRS++       
Sbjct: 833 YRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDL 892

Query: 587 --EVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHG 634
              +GFL   +R NVAVTRA+  + ++ +   + +    K  +E+  ++G
Sbjct: 893 DFNLGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENG 942


>gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo
           sapiens]
          Length = 1003

 Score =  115 bits (289), Expect = 2e-25
 Identities = 122/470 (25%), Positives = 191/470 (40%), Gaps = 94/470 (20%)

Query: 211 IIHGPPGTGKTTTVVEIILQAVKQGLK--VLCCAPSNIAVDNLVERLAL-CKQRILRLGH 267
           II GPPGTGKT T+VE I Q VK   K  +L CAPSN   D L +RL +     I RL  
Sbjct: 521 IIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLA 580

Query: 268 PARLLESIQQHSLDAVLARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLR 327
           P+R          D  +   D         K  + VF   KK Q+ R             
Sbjct: 581 PSR----------DIRMVPEDIKPCCNWDAKKGEYVFPAKKKLQEYR------------- 617

Query: 328 KELKEREEAAMLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWI 387
                     ++ +L +A  +++              P  +F  + IDE    +E    +
Sbjct: 618 ---------VLITTLITAGRLVSAQ-----------FPIDHFTHIFIDEAGHCMEPESLV 657

Query: 388 PLL----------KARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLA---------- 427
            +              + +LAGD +QL P   S      GL  SL+ERL           
Sbjct: 658 AIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGP 717

Query: 428 EEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVP 487
           + Y  + +  L   YR H  I+   +   Y G+L A + V           A     G P
Sbjct: 718 DGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDR--ERFCRWAGLPRQGFP 775

Query: 488 LLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALV-------DAGVPARDIAVVSP 540
           ++     G    +  E +  S  NP E   V+ +++ L+        A +  R + V+SP
Sbjct: 776 IIFHGVMGK---DEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISP 832

Query: 541 YNLQVDLLRQSLVHRHPEL---------EIKSVDGFQGREKEAVILSFVRSNRKG----- 586
           Y  QV+ +R  +     EL         ++ SV+ FQG+E+  +++S VRS++       
Sbjct: 833 YRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDL 892

Query: 587 --EVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHG 634
              +GFL   +R NVAVTRA+  + ++ +   + +    K  +E+  ++G
Sbjct: 893 DFNLGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENG 942


>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
            [Homo sapiens]
          Length = 2649

 Score =  115 bits (289), Expect = 2e-25
 Identities = 146/547 (26%), Positives = 218/547 (39%), Gaps = 113/547 (20%)

Query: 163  ASSLI-EVLFGRSAPSPASEIHPLTFFNTC----------LDTSQKEAVLFALSQKELAI 211
            AS L+  +  GR  P P   + P  F              L+ SQ  AV  AL +K   +
Sbjct: 2113 ASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREAL-EKPFTV 2171

Query: 212  IHGPPGTGKTTTVVEIILQAVKQ------------------GLKVLCCAPSNIAVDNL-- 251
            I GPPGTGKT   + I+    K                   G  +L C PSN +VD L  
Sbjct: 2172 IQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAG 2231

Query: 252  --VERLALCKQRIL------------------------RLGHPARLLESIQQHSLDAVLA 285
              + R+ L   R+                         R G P + L SI  H       
Sbjct: 2232 LLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAP 2291

Query: 286  RSDSAQIVA-DIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTS 344
               S++I A D R    ++F               R ++   +K L E  +      L  
Sbjct: 2292 NPYSSEIKAFDTRLQRGELFS--------------REDLVWYKKVLWEARKF----ELDR 2333

Query: 345  ANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPLLK---ARKCILAGDH 401
              V+L T    +A   LK+L       +++DE   A E    IPL++   A K +L GDH
Sbjct: 2334 HEVILCT-CSCAASASLKILDVRQ---ILVDEAGMATEPETLIPLVQFPQAEKVVLLGDH 2389

Query: 402  KQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQL 461
            KQL P   + +    GL  SL ER  E+        L  QYRMH+ I  + S   Y  +L
Sbjct: 2390 KQLRPVVKNERLQNLGLDRSLFERYHED-----AHMLDTQYRMHEGICAFPSVAFYKSKL 2444

Query: 462  TAHSSVARHLLRDLPGVAA-TEETGVPLLLVDTAG---CGLFELEEEDEQSKGNPGEV-R 516
                      LR  P V     +   P++     G     L   +E +E SK N  EV  
Sbjct: 2445 KTWQG-----LRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAE 2499

Query: 517  LVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRH-PELEIKSVDGFQGREKEAV 575
            +V +  Q  +   V  +DIAV++PYN Q   + ++L       + + S+   QG E   V
Sbjct: 2500 VVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYV 2559

Query: 576  ILSFVRSNRKGE-------------VGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAF 622
            ++S VR+  K +             +GF+ +  ++NVAVTRA+  + +I D   +     
Sbjct: 2560 LVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPL 2619

Query: 623  LKTLVEY 629
             ++L+++
Sbjct: 2620 WRSLLDF 2626



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 131/572 (22%), Positives = 210/572 (36%), Gaps = 111/572 (19%)

Query: 211  IIHGPPGTGKTTTVVEIILQAVKQG-LKVLCCAPSNIAVDNLVERLALCKQRILRLGHPA 269
            +I+GP GTGKT T+    L+ +++   KVL C  +N A D  +          +  GHP 
Sbjct: 541  LIYGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYF---HSHVSGGHPE 597

Query: 270  RLLESIQQHSLDAVLARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKE 329
                 ++    D  L+++D   +      D  Q F    + +  R +             
Sbjct: 598  AT--PLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHR------------- 642

Query: 330  LKEREEAAMLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPL 389
                              V+ T T  + +     +P  +F  ++IDE AQ LE     PL
Sbjct: 643  ------------------VVVTTTSQARE---LRVPVGFFSHILIDEAAQMLECEALTPL 681

Query: 390  LKAR---KCILAGDHKQLPPTTVSHKAALAGLSLSLMERL-------AEEYGARVVRTLT 439
              A    + +LAGDH Q+ P   S   A A    +L+ RL         E   +      
Sbjct: 682  AYASHGTRLVLAGDHMQVTPRLFSVARARAA-EHTLLHRLFLCYQQETHEVARQSRLVFH 740

Query: 440  VQYRMHQAIMRWASDTMYLGQ---LTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGC 496
              YR   AI+ + S   Y+ +   + A   V  H                PL+    AG 
Sbjct: 741  ENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPH------------PRHYPLMFCHVAGS 788

Query: 497  GLFELEEEDEQSKGNPGEVRLVSLHIQALVD------AGVPARDIAVVSPYNLQVDLLRQ 550
                  +    S  N  E+  V   +Q   +       G   R I VVS +  QV  LRQ
Sbjct: 789  ---PDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS-HGAQVSALRQ 844

Query: 551  SLVHRH-PELEIKSVDGFQGREKEAVILSFVRSNRK----GEVG--FLAEDRRINVAVTR 603
             L  R   ++ + S +   GR+   V+LS V + +     G +   F  + R +N  +TR
Sbjct: 845  ELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTR 904

Query: 604  ARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVR-------TAFEYLDDIV------PEN 650
            A+  + V+ D+  + +      L E F +    R        + E ++  V      P  
Sbjct: 905  AQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPR 964

Query: 651  YSHENSQGSSHAATKPQGPATSTR----TGSQRQEGGQEAAAPA----------RQGRKK 696
             +   + G+  AA +P G     +    T   + E G EA +PA           +    
Sbjct: 965  GTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDITATTAQTEAAAA 1024

Query: 697  PAGKSLASE-APSQPSLNGGSPEGVESQDGVD 727
            PAG ++  +  P   +    +  GVES +  D
Sbjct: 1025 PAGDAVKEDVVPGACAAGAAAAAGVESTEAED 1056


>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
            [Homo sapiens]
          Length = 2080

 Score =  115 bits (289), Expect = 2e-25
 Identities = 146/547 (26%), Positives = 218/547 (39%), Gaps = 113/547 (20%)

Query: 163  ASSLI-EVLFGRSAPSPASEIHPLTFFNTC----------LDTSQKEAVLFALSQKELAI 211
            AS L+  +  GR  P P   + P  F              L+ SQ  AV  AL +K   +
Sbjct: 1544 ASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREAL-EKPFTV 1602

Query: 212  IHGPPGTGKTTTVVEIILQAVKQ------------------GLKVLCCAPSNIAVDNL-- 251
            I GPPGTGKT   + I+    K                   G  +L C PSN +VD L  
Sbjct: 1603 IQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAG 1662

Query: 252  --VERLALCKQRIL------------------------RLGHPARLLESIQQHSLDAVLA 285
              + R+ L   R+                         R G P + L SI  H       
Sbjct: 1663 LLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAP 1722

Query: 286  RSDSAQIVA-DIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTS 344
               S++I A D R    ++F               R ++   +K L E  +      L  
Sbjct: 1723 NPYSSEIKAFDTRLQRGELFS--------------REDLVWYKKVLWEARKF----ELDR 1764

Query: 345  ANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPLLK---ARKCILAGDH 401
              V+L T    +A   LK+L       +++DE   A E    IPL++   A K +L GDH
Sbjct: 1765 HEVILCT-CSCAASASLKILDVRQ---ILVDEAGMATEPETLIPLVQFPQAEKVVLLGDH 1820

Query: 402  KQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQL 461
            KQL P   + +    GL  SL ER  E+        L  QYRMH+ I  + S   Y  +L
Sbjct: 1821 KQLRPVVKNERLQNLGLDRSLFERYHED-----AHMLDTQYRMHEGICAFPSVAFYKSKL 1875

Query: 462  TAHSSVARHLLRDLPGVAA-TEETGVPLLLVDTAG---CGLFELEEEDEQSKGNPGEV-R 516
                      LR  P V     +   P++     G     L   +E +E SK N  EV  
Sbjct: 1876 KTWQG-----LRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAE 1930

Query: 517  LVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRH-PELEIKSVDGFQGREKEAV 575
            +V +  Q  +   V  +DIAV++PYN Q   + ++L       + + S+   QG E   V
Sbjct: 1931 VVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYV 1990

Query: 576  ILSFVRSNRKGE-------------VGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAF 622
            ++S VR+  K +             +GF+ +  ++NVAVTRA+  + +I D   +     
Sbjct: 1991 LVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPL 2050

Query: 623  LKTLVEY 629
             ++L+++
Sbjct: 2051 WRSLLDF 2057



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 101/418 (24%), Positives = 158/418 (37%), Gaps = 71/418 (16%)

Query: 364 LPESYFDVVVIDECAQALEASCWIPLLKAR---KCILAGDHKQLPPTTVSHKAALAGLSL 420
           +P  +F  ++IDE AQ LE     PL  A    + +LAGDH Q+ P   S   A A    
Sbjct: 87  VPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAA-EH 145

Query: 421 SLMERL-------AEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQ---LTAHSSVARH 470
           +L+ RL         E   +        YR   AI+ + S   Y+ +   + A   V  H
Sbjct: 146 TLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPH 205

Query: 471 LLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVD--- 527
                           PL+    AG       +    S  N  E+  V   +Q   +   
Sbjct: 206 ------------PRHYPLMFCHVAGS---PDRDMSMASWLNLAEIAQVVEKVQEAYNTWP 250

Query: 528 ---AGVPARDIAVVSPYNLQVDLLRQSLVHRH-PELEIKSVDGFQGREKEAVILSFVRSN 583
               G   R I VVS +  QV  LRQ L  R   ++ + S +   GR+   V+LS V + 
Sbjct: 251 SCWGGREQRCICVVS-HGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTC 309

Query: 584 RK----GEVG--FLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVR 637
           +     G +   F  + R +N  +TRA+  + V+ D+  + +      L E F +    R
Sbjct: 310 QSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVER 369

Query: 638 -------TAFEYLDDIV------PENYSHENSQGSSHAATKPQGPATSTR----TGSQRQ 680
                   + E ++  V      P   +   + G+  AA +P G     +    T   + 
Sbjct: 370 HSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKA 429

Query: 681 EGGQEAAAPA----------RQGRKKPAGKSLASE-APSQPSLNGGSPEGVESQDGVD 727
           E G EA +PA           +    PAG ++  +  P   +    +  GVES +  D
Sbjct: 430 EPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAED 487


>gi|54792138 helicase with zinc finger domain [Homo sapiens]
          Length = 1942

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 126/476 (26%), Positives = 191/476 (40%), Gaps = 121/476 (25%)

Query: 192  LDTSQKEAVLFALS----QKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIA 247
            L+  QKEAVL   +    Q    +I GP GTGKT T+     QAVK  L+          
Sbjct: 642  LNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLA----QAVKHILQ---------- 687

Query: 248  VDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIR-KDIDQVFVK 306
                                        QQ +   +   S+SA   AD+  KD    +V+
Sbjct: 688  ----------------------------QQETRILICTHSNSA---ADLYIKDYLHPYVE 716

Query: 307  NKKTQDKREKSNFRNE-IKLLRKELKE---------REEAAMLESLTSANVVLATNTGAS 356
                Q +  +  FRN  +K +   + +           +    E +    VV+ T   + 
Sbjct: 717  AGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQ 776

Query: 357  ADGPLKLLPESYFDVVVIDECAQALEASCWIPLLKAR---KCILAGDHKQLPPTTVSHKA 413
                L L P  +F  +++DE AQA+E    +PL  A    + +LAGDH QL P   S  A
Sbjct: 777  YLCQLDLEP-GFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFA 835

Query: 414  ALAGLSLSLMERLAEEYGA----RVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVAR 469
                L +SL++RL E Y A    R++  L   YR H+AI+ + S+  Y G+L A      
Sbjct: 836  RERNLHVSLLDRLYEHYPAEFPCRIL--LCENYRSHEAIINYTSELFYEGKLMASGKQPA 893

Query: 470  HLLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQAL---- 525
            H            +   PL      G    +++E++  +  N  EV  V   ++ L    
Sbjct: 894  H------------KDFYPLTFFTARG---EDVQEKNSTAFYNNAEVFEVVERVEELRRKW 938

Query: 526  ------VDAGVPARDIAVVSPYNLQVDLLRQSL-VHRHPELEIKSVDGFQGREKEAVILS 578
                  +D G     I VV+PY  QV  +R  L   R  ++ ++ V   QG++   + LS
Sbjct: 939  PVAWGKLDDG----SIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLS 994

Query: 579  FVR---------------------SNRKGEVGFLAEDRRINVAVTRARRHVAVICD 613
             VR                     S    + GFL+  + +N A+TRA+  VAV+ D
Sbjct: 995  TVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGD 1050


>gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]
          Length = 1918

 Score = 84.7 bits (208), Expect = 4e-16
 Identities = 93/323 (28%), Positives = 159/323 (49%), Gaps = 21/323 (6%)

Query: 288  DSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANV 347
            D  Q+    R  + +++++  +   +R+  ++  + +   + + E      L  L  A V
Sbjct: 921  DVWQLDLSSRWQLYRLWLQLYQADTRRKILSYERQYRTSAERMAELRLQEDLHILKDAQV 980

Query: 348  VLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPLLKA-RKCILAGDHKQLPP 406
            V  T TGA+     ++L +    +V+++E A+ LEA     L KA +  IL GDH+QL P
Sbjct: 981  VGMTTTGAAKYR--QILQKVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRP 1038

Query: 407  TT-VSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHS 465
            +  V   A    L +SL ERL +      VR L  Q+RM   I R  +  +Y   L  H 
Sbjct: 1039 SANVYDLAKNFNLEVSLFERLVK-VNIPFVR-LNYQHRMCPEIARLLTPHIYQ-DLENHP 1095

Query: 466  SVARHLLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVR-LVSLHIQA 524
            SV ++    + GV++       L  V+       E E ++ +S  N  E   +V L    
Sbjct: 1096 SVLKY--EKIKGVSSN------LFFVEH---NFPEQEIQEGKSHQNQHEAHFVVELCKYF 1144

Query: 525  LVDAGVPARDIAVVSPYNLQVDLLRQSLVHR-HPELEIKSVDGFQGREKEAVILSFVRSN 583
            L    +P++ I +++ Y  Q+  LR+ +  +    + +  VD +QG E + ++LS VRSN
Sbjct: 1145 LCQEYLPSQ-ITILTTYTGQLFCLRKLMPAKTFAGVRVHVVDKYQGEENDIILLSLVRSN 1203

Query: 584  RKGEVGFLAEDRRINVAVTRARR 606
            ++G+VGFL    RI VA++RA++
Sbjct: 1204 QEGKVGFLQISNRICVALSRAKK 1226



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 35/85 (41%), Positives = 48/85 (56%), Gaps = 11/85 (12%)

Query: 192 LDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEI---------ILQAVKQGLKVLCCA 242
           LD SQ EA+ FAL+ +ELAII GPPGTGKT   ++I         + Q   Q   +L   
Sbjct: 598 LDDSQMEALQFALT-RELAIIQGPPGTGKTYVGLKIVQALLTNESVWQISLQKFPILVVC 656

Query: 243 PSNIAVDNLVERLALC-KQRILRLG 266
            +N A+D  +E +  C K  I+R+G
Sbjct: 657 YTNHALDQFLEGIYNCQKTSIVRVG 681


>gi|38788372 aquarius [Homo sapiens]
          Length = 1485

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 130/527 (24%), Positives = 206/527 (39%), Gaps = 136/527 (25%)

Query: 189  NTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQ--GLKVLCCAPSNI 246
            NT   T  +   + A  Q  L ++ GPPGTGKT   V+II          + L    SN 
Sbjct: 798  NTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQ 857

Query: 247  AVDNLVER---LALCKQRILRLGHPARLLESIQQHS----LDAVLAR------------- 286
            A++ L E+   L + ++ +LRLGH    LE+ +  S    ++ VLAR             
Sbjct: 858  ALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGRVNYVLARRIELLEEVKRLQK 917

Query: 287  -----SDSA------------QIVADIRKDIDQVFVKNKKTQDKREKSNF---------- 319
                  D++            Q+++   + I +V  K     D  E S F          
Sbjct: 918  SLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVTEVSTFFPFHEYFANA 977

Query: 320  --------------------RNEIKLLRKELKEREEAAMLES---------LTSANVVLA 350
                                   IK +  +L+E   + +L S         +  A ++  
Sbjct: 978  PQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAM 1037

Query: 351  TNTGASAD-GPLKLLPESYFDVVVIDECAQALEASCWIPLL---------KARKCILAGD 400
            T T A+     L  L   Y +++ ++E AQ LE   +IPLL         + ++ I+ GD
Sbjct: 1038 TCTHAALKRHDLVKLGFKYDNIL-MEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGD 1096

Query: 401  HKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMH-QAIMRWASDTMYLG 459
            H QLPP        +  ++      + +    R VR       +  Q   R +   +Y  
Sbjct: 1097 HHQLPP-------VIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNW 1149

Query: 460  QLTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGCGL---FEL-EEEDEQSKG----- 510
            +           L +LP V    E         TA  GL   F+L   ED Q  G     
Sbjct: 1150 RYKN--------LGNLPHVQLLPE-------FSTANAGLLYDFQLINVEDFQGVGESEPN 1194

Query: 511  -----NPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHR---HPEL--- 559
                 N GE   V      +   G PA  I++++ YN Q  L+R  +  R   +P +   
Sbjct: 1195 PYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRP 1254

Query: 560  -EIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRAR 605
             ++ +VD FQG++ + ++LS VR+     VG L + RR+ VA++RAR
Sbjct: 1255 NKVTTVDRFQGQQNDYILLSLVRTR---AVGHLRDVRRLVVAMSRAR 1298


>gi|38505213 YTH domain containing 2 [Homo sapiens]
          Length = 1430

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 18/101 (17%)

Query: 703 ASEAPSQPSLNGGS--------PEGVESQDGVDHFRA----------MIVEFMASKKMQL 744
           +S +P QP+  GG         P G     G+   R            +  F    + ++
Sbjct: 5   SSVSPRQPAPGGGGGGGPSPCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREM 64

Query: 745 EFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKR 785
           EFP SL S +R  +H++++  GL   S G+G  R++TV K+
Sbjct: 65  EFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKK 105



 Score = 35.0 bits (79), Expect = 0.35
 Identities = 21/90 (23%), Positives = 47/90 (52%), Gaps = 5/90 (5%)

Query: 196 QKEAVLFALSQKELAIIHGPPGTGKTTTVVEIIL-QAVKQGL--KVLCCAPSNIAVDNLV 252
           ++E ++  + + ++ +I G  G+GKTT + + +L    K G+  ++ C  P  +A   + 
Sbjct: 198 KQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVA 257

Query: 253 ERLALCKQRIL--RLGHPARLLESIQQHSL 280
           ER+A  ++  +   +G+  RL   +   +L
Sbjct: 258 ERVAAERRERIGQTIGYQIRLESRVSPKTL 287


>gi|157266334 tubby like protein 1 [Homo sapiens]
          Length = 542

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 68/283 (24%), Positives = 102/283 (36%), Gaps = 41/283 (14%)

Query: 641 EYLDDIVPENYSHENSQGSSHAATKP-QGPATSTRTGSQRQEGGQEAAAPARQGRKKPAG 699
           E L ++   +  HE    S  A  +P Q PA + R   +R E  +       + RK  AG
Sbjct: 6   ETLREVWASDSGHEEESLSPEAPRRPKQRPAPAQRLRKKRTEAPESPCPTGSKPRKPGAG 65

Query: 700 KS-LASEAPSQPSLNGGSPEGVESQ---DGVDHFRAMIVEFMASKKMQLEFPPSLNSHDR 755
           ++    E PS       +P+ V ++   D     R     F+ ++    E        D 
Sbjct: 66  RTGRPREEPSPDPAQARAPQTVYARFLRDPEAKKRDPRETFLVARAPDAEDEEEEEEEDE 125

Query: 756 LRVHQIAEEHG----------LRHDSSGEGKRRFITVSKRAPRPRAALGPPAGTGGPAPL 805
               + AEE            LR  SS + K R      +A  PR  LG P     P PL
Sbjct: 126 EDEEEEAEEKKEKILLPPKKPLREKSSADLKER----RAKAQGPRGDLGSPDPP--PKPL 179

Query: 806 Q---PVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQRVRSAQGQPASKEQQASGQ---- 858
           +      P    T+    +++G  + D            +   G PAS  +  +      
Sbjct: 180 RVRNKEAPAGEGTKMRKTKKKGSGEAD------------KDPSGSPASARKSPAAMFLVG 227

Query: 859 QKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAK 901
           +  P+KK  K KG P      EE+ E   +  +K  N  G AK
Sbjct: 228 EGSPDKKALKKKGTP-KGARKEEEEEEEAATVIKKSNQKGKAK 269


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 58/254 (22%), Positives = 92/254 (36%), Gaps = 41/254 (16%)

Query: 660 SHAATKPQGPATST--RTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSP 717
           S   TK + P+ S+  R GS      +EA +P    R  P+ +  A +  S P       
Sbjct: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPP----- 699

Query: 718 EGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKR 777
                           V   AS   Q    PS ++    RV +  E   ++  +S   + 
Sbjct: 700 ----------------VRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQS 743

Query: 778 RFITVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLER 837
                 +R    R+  G P      A   P PP+P Q+ Q P     P  P      +++
Sbjct: 744 -----VRRVSSSRSVSGSPEPA---AKKPPAPPSPVQS-QSPSTNWSPAVP------VKK 788

Query: 838 LQRVRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTC 897
            +    +   P + +Q+  G++K  +K KK  K          +  +A+ +AA  A    
Sbjct: 789 AKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPA 848

Query: 898 GFAKCTAGVTTLGQ 911
             A   A  TTL Q
Sbjct: 849 AIA---AATTTLAQ 859



 Score = 30.4 bits (67), Expect = 8.6
 Identities = 46/192 (23%), Positives = 64/192 (33%), Gaps = 23/192 (11%)

Query: 661 HAATKPQGPATSTRTG-----SQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGG 715
           H  + P  P   TR       S R    + + +P R   K    K         P+    
Sbjct: 399 HRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR 458

Query: 716 SPEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLR-HDSSGE 774
             E  ES++  D    M       ++ Q       +S D        +E   R H  +GE
Sbjct: 459 KVELSESEE--DKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE 516

Query: 775 -GKRRFITVSKRA---PRPRAALGPPAGTGGPAPLQPV-----------PPTPAQTEQPP 819
            G+RR  + S+ A   PR R     P G    +P  P            PP   +T  PP
Sbjct: 517 VGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPP 576

Query: 820 REQRGPDQPDLR 831
             +R P  P  R
Sbjct: 577 PRRRTPSPPPRR 588


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 8/96 (8%)

Query: 789  PRAALGPPAGTGGPAPLQPVPPTPAQTEQPPRE-----QRGPDQPDLRTLHLERLQRVRS 843
            P   L PP     P+P  P PP  A    PP E        P+ PD R LHL + Q   +
Sbjct: 1497 PPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAA 1556

Query: 844  AQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPT 879
              G+   +  ++ G+    E+ +   +   A D+P+
Sbjct: 1557 VCGETDEEAGESGGEGIFRERDEFVIR---AEDIPS 1589



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 38/147 (25%), Positives = 62/147 (42%), Gaps = 22/147 (14%)

Query: 740  KKMQLEFPPSLNSHDRLRVHQIAEEHG--LRHDSSGEGKRRFITVSKRAPRPRAALGPPA 797
            +++ ++F  ++N  D +RV      H   +    SG+ K         AP P+A   PP 
Sbjct: 1643 QRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPP- 1701

Query: 798  GTGGPAPLQPVPPTPAQTEQPPR--------EQRGPDQPD-LRTLHLERLQRVRSAQGQP 848
                    +P  P    +E+PP         E   P++P  LR +  E+ +   +   +P
Sbjct: 1702 --------KPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERP 1753

Query: 849  ASKEQQASGQQKLPEKKKKKAKGHPAT 875
               E+  SG+Q  PE  +  A G PAT
Sbjct: 1754 LRGERATSGRQTRPE--RSLATGQPAT 1778


>gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]
          Length = 562

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 68/288 (23%), Positives = 111/288 (38%), Gaps = 38/288 (13%)

Query: 660 SHAATKPQGPATSTRTGSQRQEGGQEAA----APARQGRKKPAGKSLASEAPSQP----- 710
           S +  +P+G A +   G+   E   E A    APA      P   +  ++ P  P     
Sbjct: 35  SDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAG 94

Query: 711 -SLNGGSPEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLN----SHDRLR----VHQI 761
            S  G SPEG E  D  D      V+   +  +  +FPPS +    S  RL+    +H  
Sbjct: 95  RSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLT-QFPPSQSEERSSGFRLKPPTLIHGQ 153

Query: 762 AEEHGLRHDSSGEGKRRFITVSK-RAPRPRAALG--PPAGTGGPA-PLQPVPPTPAQTE- 816
           A   GL      E +R  +  +  +AP+P+A     P +GT G + P       PA +  
Sbjct: 154 APSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPD 213

Query: 817 ----QPPREQRGPDQPDLRTLHLERLQRVRSAQGQPASKEQQASGQQ-----KLPEKKKK 867
               + P E    ++   +       +     +  PA+++    GQ      KL  +   
Sbjct: 214 TAAWRSPSEAADEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVD 273

Query: 868 KAK----GHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVTTLGQ 911
           +A     GHP+ D PT  ++  L   +   +N+   A  ++     GQ
Sbjct: 274 EADMENAGHPSADTPTATNY-FLQYISSSLENSTNSADASSNKFVFGQ 320


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 18/39 (46%), Positives = 21/39 (53%)

Query: 790 RAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQP 828
           R  +GP  G  GP P  P PP   Q +QPP +Q  P QP
Sbjct: 44  RGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQP 82


>gi|21359918 zinc finger, AN1-type domain 6 [Homo sapiens]
          Length = 208

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 849 ASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVTT 908
           +S+    S  + +PE +  +A        P+EE  ++L     K  N C   +   G+T 
Sbjct: 102 SSQLDSTSVDKAVPETEDVQASVSDTAQQPSEEQSKSLEKPKQKK-NRCFMCRKKVGLT- 159

Query: 909 LGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAG 953
            G  C+ C   YC  H   ++H C    +A A ++I +E  +  G
Sbjct: 160 -GFECR-CGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVG 202


>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
          Length = 1041

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 18/62 (29%), Positives = 36/62 (58%), Gaps = 2/62 (3%)

Query: 197 KEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQA--VKQGLKVLCCAPSNIAVDNLVER 254
           +E +L A++  ++ II G  G+GKTT + + + +     +G+K+ C  P  +A  ++  R
Sbjct: 405 REELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAAR 464

Query: 255 LA 256
           +A
Sbjct: 465 VA 466


>gi|239753786 PREDICTED: hypothetical protein LOC100129786 [Homo
           sapiens]
          Length = 210

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 53/220 (24%), Positives = 87/220 (39%), Gaps = 24/220 (10%)

Query: 649 ENYSHENSQGSSHAATKPQG--PATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEA 706
           E +    S G+   A +  G  P  STR      +  +E+  P  + R+ P     A E+
Sbjct: 4   EEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARES 63

Query: 707 P-SQPSLNGGSPEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEH 765
           P +QP+ +   P    +Q   + ++    E       Q   P +            +E  
Sbjct: 64  PGNQPTQSMREPR-TPAQSTRESWKPTHAE-------QARAPETDQ-------RGASESP 108

Query: 766 GLRH-DSSGEGKRRFITVSKRAPR-PRAALGPPAGTGGPAPLQPVPPTPAQ----TEQPP 819
           G R   S+ E +   +  ++++PR PR A G P      +  +P  PT A+     E  P
Sbjct: 109 GNRPTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDP 168

Query: 820 REQRGPDQPDLRTLHLERLQRVRSAQGQPASKEQQASGQQ 859
            E RG  +   RT HL  + RV   Q +   +E+    Q+
Sbjct: 169 HEARGSHRFIPRTTHLLGVFRVLKTQERKRLEEEVKMSQK 208


>gi|169167301 PREDICTED: hypothetical protein LOC100129786 [Homo
           sapiens]
          Length = 210

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 53/220 (24%), Positives = 87/220 (39%), Gaps = 24/220 (10%)

Query: 649 ENYSHENSQGSSHAATKPQG--PATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEA 706
           E +    S G+   A +  G  P  STR      +  +E+  P  + R+ P     A E+
Sbjct: 4   EEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARES 63

Query: 707 P-SQPSLNGGSPEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEH 765
           P +QP+ +   P    +Q   + ++    E       Q   P +            +E  
Sbjct: 64  PGNQPTQSMREPR-TPAQSTRESWKPTHAE-------QARAPETDQ-------RGASESP 108

Query: 766 GLRH-DSSGEGKRRFITVSKRAPR-PRAALGPPAGTGGPAPLQPVPPTPAQ----TEQPP 819
           G R   S+ E +   +  ++++PR PR A G P      +  +P  PT A+     E  P
Sbjct: 109 GNRPTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDP 168

Query: 820 REQRGPDQPDLRTLHLERLQRVRSAQGQPASKEQQASGQQ 859
            E RG  +   RT HL  + RV   Q +   +E+    Q+
Sbjct: 169 HEARGSHRFIPRTTHLLGVFRVLKTQERKRLEEEVKMSQK 208


>gi|169166477 PREDICTED: hypothetical protein LOC100129786 [Homo
           sapiens]
          Length = 210

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 53/220 (24%), Positives = 87/220 (39%), Gaps = 24/220 (10%)

Query: 649 ENYSHENSQGSSHAATKPQG--PATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEA 706
           E +    S G+   A +  G  P  STR      +  +E+  P  + R+ P     A E+
Sbjct: 4   EEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARES 63

Query: 707 P-SQPSLNGGSPEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEH 765
           P +QP+ +   P    +Q   + ++    E       Q   P +            +E  
Sbjct: 64  PGNQPTQSMREPR-TPAQSTRESWKPTHAE-------QARAPETDQ-------RGASESP 108

Query: 766 GLRH-DSSGEGKRRFITVSKRAPR-PRAALGPPAGTGGPAPLQPVPPTPAQ----TEQPP 819
           G R   S+ E +   +  ++++PR PR A G P      +  +P  PT A+     E  P
Sbjct: 109 GNRPTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDP 168

Query: 820 REQRGPDQPDLRTLHLERLQRVRSAQGQPASKEQQASGQQ 859
            E RG  +   RT HL  + RV   Q +   +E+    Q+
Sbjct: 169 HEARGSHRFIPRTTHLLGVFRVLKTQERKRLEEEVKMSQK 208


>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
          Length = 1444

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 6/122 (4%)

Query: 764 EHGLRHDSSGEGKRRFITVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPP-REQ 822
           E GL  D +       +   K +P+    +G P     P P  P PPTP +   P    +
Sbjct: 742 EQGLHPDLASLAPLEIVPFEKASPQATVEVGGPGNLSPPLPPAPPPPTPLEESTPVLLSK 801

Query: 823 RGPDQPD----LRT-LHLERLQRVRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDL 877
            GP++ D    LRT L++++L+   S +     + ++A+ +    +  K  A        
Sbjct: 802 GGPEREDSSRKLRTDLYIDQLKSQDSPEISSLCQGEEATPRHSDKQNSKNAASEGKGCGF 861

Query: 878 PT 879
           P+
Sbjct: 862 PS 863


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 52/194 (26%), Positives = 72/194 (37%), Gaps = 26/194 (13%)

Query: 662  AATKP-QGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGV 720
            AA +P   P   T +G +  +    +  P           SL++E        GG+  GV
Sbjct: 1659 AAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGV 1718

Query: 721  ES-QDGVDHFRAMI--VEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKR 777
             S  + +D + A +    F  S      +PP L +  +LR   +    GLR   SG G R
Sbjct: 1719 ASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSG-GLR 1777

Query: 778  RFITVSKRAPRP-----------RAALGPPAG--TGGPAPLQP-VPPTPAQTEQ------ 817
              +T +                 RA  GPP     GGP  ++P VPP P  T        
Sbjct: 1778 DPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKL 1837

Query: 818  -PPREQRGPDQPDL 830
             P  E  GP  P L
Sbjct: 1838 LPWEEGPGPPPPPL 1851



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 1/55 (1%)

Query: 791  AALGPPAGTGGPAPLQPVPPTPAQ-TEQPPREQRGPDQPDLRTLHLERLQRVRSA 844
            AA G P   G PAP  P P  P    + PP    G ++ D R+     L+ + SA
Sbjct: 1640 AAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSA 1694


>gi|21361684 G patch domain containing 1 [Homo sapiens]
          Length = 931

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 57/258 (22%), Positives = 100/258 (38%), Gaps = 45/258 (17%)

Query: 647 VPENYSHENSQGSSHAATKPQGPATS-------TRTGSQRQEGGQEAAAPARQGRKKPAG 699
           +PE  S   +Q SS   ++ +GP  S       T    ++++   E  + AR   + P  
Sbjct: 653 LPETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQ 712

Query: 700 KS---LASEAPSQPSLNGGSP---------EGVESQDGVDHFRAMIVEFMASKKMQLEFP 747
           +S   +  E    P L+             EG  S+  +D FRA+       K       
Sbjct: 713 QSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEK------- 765

Query: 748 PSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFITVSKRAPRPRAALGPPAGTGGPAPLQP 807
            S +S D        E+     D +G G+  F +         +++   A    PAP +P
Sbjct: 766 -SSSSED--------EQGDSEDDQAGSGEANFQSSQDTDLGETSSV---AHALVPAPQEP 813

Query: 808 VPPTPAQTEQ-PPREQRGPDQPDL------RTLHLERLQRVRSAQGQPASKEQQASGQQK 860
            P  P Q  Q   RE+ GP  P +      +TL + + ++ +  + +  +K++    ++K
Sbjct: 814 PPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEK 873

Query: 861 LPEKKKKKAKGHPATDLP 878
             + +K K KG      P
Sbjct: 874 KKKHRKHKHKGKQKNKKP 891


>gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]
          Length = 567

 Score = 39.3 bits (90), Expect = 0.019
 Identities = 67/293 (22%), Positives = 113/293 (38%), Gaps = 43/293 (14%)

Query: 660 SHAATKPQGPATSTRTGSQRQEGGQEAA----APARQGRKKPAGKSLASEAPSQP----- 710
           S +  +P+G A +   G+   E   E A    APA      P   +  ++ P  P     
Sbjct: 35  SDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAG 94

Query: 711 -SLNGGSPEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLN----SHDRLR----VHQI 761
            S  G SPEG E  D  D      V+   +  +  +FPPS +    S  RL+    +H  
Sbjct: 95  RSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLT-QFPPSQSEERSSGFRLKPPTLIHGQ 153

Query: 762 AEEHGLRHDSSGEGKRRFITVSK-RAPRPRAALG--PPAGTGGPA-PLQPVPPTPAQTEQ 817
           A   GL      E +R  +  +  +AP+P+A     P +GT G + P       PA +  
Sbjct: 154 APSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPD 213

Query: 818 PPREQRGPDQPD----LRTLHLERLQRVRSAQGQPASKEQQASGQ-----QKLPEKKK-- 866
               +   +  D    L     ++ +   +++ +   K+  A+ Q     Q L ++ K  
Sbjct: 214 TAAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLI 273

Query: 867 --------KKAKGHPATDLPTEEDFEALVSAAVKADNTCGFAKCTAGVTTLGQ 911
                    +  GHP+ D PT  ++  L   +   +N+   A  ++     GQ
Sbjct: 274 NESVDEADMENAGHPSADTPTATNY-FLQYISSSLENSTNSADASSNKFVFGQ 325


>gi|150378549 tangerin [Homo sapiens]
          Length = 1523

 Score = 39.3 bits (90), Expect = 0.019
 Identities = 56/234 (23%), Positives = 86/234 (36%), Gaps = 42/234 (17%)

Query: 654  ENSQGSSHAATKPQG--PATSTRT---GSQRQEGGQEAAAPARQGRKKPAGKSLASEAPS 708
            E  Q    AA +  G  P  ++R    G   ++GG EA   +R       G    + AP 
Sbjct: 1188 EGPQEPKEAADRADGAAPGVASRNAVAGRASKDGGAEAPRESRPAEVPAEGLVNGAGAPG 1247

Query: 709  -------QPSLNG--GSPEGVESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVH 759
                   +PS+NG  GS     +     H R    + +  ++ +L    S +  D     
Sbjct: 1248 GGGVRLRRPSVNGEPGSVPPPRAHGSFSHVRD--ADLLKKRRSRLRNSSSFSMDD----- 1300

Query: 760  QIAEEHGLRHDSSGEGKRRFITVSKRAPRPRAALGPPAGT------GGPAPLQPVPPTPA 813
                + G    ++ EG+         AP P  A GPP         GG +P +  PP+P 
Sbjct: 1301 ---PDAGAMGAAAAEGQ---------APDPSPAPGPPTAADSQQPPGGSSPSEEPPPSPG 1348

Query: 814  QTEQPPREQRGPDQPDLRTLHLERLQRV---RSAQGQPASKEQQASGQQKLPEK 864
            +     R Q            LE+ QR    R+A+ +   +    SG  KL E+
Sbjct: 1349 EEAGLQRFQDTSQYVCAELQALEQEQRQIDGRAAEVEMQLRSLMESGANKLQEE 1402


>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
           sapiens]
          Length = 1386

 Score = 39.3 bits (90), Expect = 0.019
 Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 7/76 (9%)

Query: 196 QKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQG-----LKVLCCAPSNIAVDN 250
           ++E +L  L + ++ +I G  G GKTT + + IL     G       ++C  P  I+  +
Sbjct: 549 ERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPRRISAIS 608

Query: 251 LVERLALCKQRILRLG 266
           + ER+A  K+R  R+G
Sbjct: 609 VAERVA--KERAERVG 622


>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 38.9 bits (89), Expect = 0.024
 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 26/121 (21%)

Query: 791 AALGPPAGTGGPAPLQPVPPTPAQTEQPPRE--------QRGP------------DQPDL 830
           AA GPP G   P   QP PP P    Q  RE        QR P            D    
Sbjct: 170 AAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKR 229

Query: 831 RTL------HLERLQRVRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFE 884
           RTL       LE+++R +  + +    EQQ S   K  +K  + A+G     LP    F+
Sbjct: 230 RTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFD 289

Query: 885 A 885
           +
Sbjct: 290 S 290


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,878,961
Number of Sequences: 37866
Number of extensions: 1971644
Number of successful extensions: 16122
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 392
Number of HSP's that attempted gapping in prelim test: 14284
Number of HSP's gapped (non-prelim): 2104
length of query: 993
length of database: 18,247,518
effective HSP length: 112
effective length of query: 881
effective length of database: 14,006,526
effective search space: 12339749406
effective search space used: 12339749406
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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