BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239756837 PREDICTED: similar to pleckstrin homology domain containing, family M (with RUN domain) member 1, partial [Homo sapiens] (623 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239756837 PREDICTED: similar to pleckstrin homology domain co... 1267 0.0 gi|40538728 pleckstrin homology domain containing, family M (wit... 1094 0.0 gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo ... 877 0.0 gi|122937347 pleckstrin homology domain containing, family M, me... 173 5e-43 gi|46447820 differentially expressed in FDCP 8 isoform 1 [Homo s... 102 1e-21 gi|156151402 hypothetical protein LOC80183 [Homo sapiens] 91 2e-18 gi|224548938 hypothetical protein LOC9711 isoform 1 [Homo sapiens] 69 1e-11 gi|150456467 hypothetical protein LOC9711 isoform 2 [Homo sapiens] 69 1e-11 gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 40 0.008 gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 40 0.008 gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 40 0.008 gi|150456471 doublecortin domain containing 2B [Homo sapiens] 37 0.071 gi|158631203 dual adaptor of phosphotyrosine and 3-phosphoinosit... 36 0.093 gi|50083291 amyloid beta A4 precursor protein-binding, family B,... 35 0.27 gi|5174547 mitogen-activated protein kinase kinase kinase 5 [Hom... 35 0.27 gi|38787957 tensin like C1 domain containing phosphatase isoform... 34 0.46 gi|38787941 tensin like C1 domain containing phosphatase isoform... 34 0.46 gi|33457316 pleckstrin homology domain containing, family O memb... 34 0.46 gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 33 0.60 gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 33 0.60 gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 33 0.60 gi|7662230 ring finger protein 40 [Homo sapiens] 33 0.78 gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 32 1.3 gi|32967599 ankyrin 3 isoform 2 [Homo sapiens] 32 1.3 gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 32 1.3 gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 32 1.3 gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens] 32 1.7 gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens] 32 1.7 gi|14249672 protein phosphatase 1, regulatory (inhibitor) subuni... 32 1.7 gi|116805330 small conductance calcium-activated potassium chann... 31 3.0 >gi|239756837 PREDICTED: similar to pleckstrin homology domain containing, family M (with RUN domain) member 1, partial [Homo sapiens] Length = 623 Score = 1267 bits (3278), Expect = 0.0 Identities = 623/623 (100%), Positives = 623/623 (100%) Query: 1 QQKNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRHFSQEPRKNCSLGAL 60 QQKNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRHFSQEPRKNCSLGAL Sbjct: 1 QQKNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRHFSQEPRKNCSLGAL 60 Query: 61 DQACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGTVERRGAMGIWKELF 120 DQACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGTVERRGAMGIWKELF Sbjct: 61 DQACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGTVERRGAMGIWKELF 120 Query: 121 CELSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAE 180 CELSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAE Sbjct: 121 CELSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAE 180 Query: 181 DWLDLVREALQKVRPQQEDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDW 240 DWLDLVREALQKVRPQQEDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDW Sbjct: 181 DWLDLVREALQKVRPQQEDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDW 240 Query: 241 SSAQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDI 300 SSAQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDI Sbjct: 241 SSAQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDI 300 Query: 301 LPDTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLD 360 LPDTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLD Sbjct: 301 LPDTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLD 360 Query: 361 ENCQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLY 420 ENCQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLY Sbjct: 361 ENCQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLY 420 Query: 421 YCDICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVER 480 YCDICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVER Sbjct: 421 YCDICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVER 480 Query: 481 MHLIGRRREQLKLLGDYLGLCRSGALKELSKRAGPESASLKTASSILAAVLPEPGLLRAR 540 MHLIGRRREQLKLLGDYLGLCRSGALKELSKRAGPESASLKTASSILAAVLPEPGLLRAR Sbjct: 481 MHLIGRRREQLKLLGDYLGLCRSGALKELSKRAGPESASLKTASSILAAVLPEPGLLRAR 540 Query: 541 VCLEQVPRGSQGVVKSLGSGGALSPSLVKEPGTCTGMQTCVDQMPVGCAECKTVFHQSCQ 600 VCLEQVPRGSQGVVKSLGSGGALSPSLVKEPGTCTGMQTCVDQMPVGCAECKTVFHQSCQ Sbjct: 541 VCLEQVPRGSQGVVKSLGSGGALSPSLVKEPGTCTGMQTCVDQMPVGCAECKTVFHQSCQ 600 Query: 601 AVVKKGCPRCARRRKYQEQNIFA 623 AVVKKGCPRCARRRKYQEQNIFA Sbjct: 601 AVVKKGCPRCARRRKYQEQNIFA 623 >gi|40538728 pleckstrin homology domain containing, family M (with RUN domain) member 1 [Homo sapiens] Length = 1056 Score = 1094 bits (2829), Expect = 0.0 Identities = 557/634 (87%), Positives = 566/634 (89%), Gaps = 27/634 (4%) Query: 3 KNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRHFSQEPRKNCSLGALDQ 62 KNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRHFSQEPRKNCSLGALDQ Sbjct: 437 KNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRHFSQEPRKNCSLGALDQ 496 Query: 63 ACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGTVERRGAMGIWKELFCE 122 ACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGTVERRGAMGIWKELFCE Sbjct: 497 ACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGTVERRGAMGIWKELFCE 556 Query: 123 LSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDW 182 LSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDW Sbjct: 557 LSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDW 616 Query: 183 LDLVREALQKVRPQQEDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSS 242 LD VREALQKVRPQQEDEWVNVQY DQPEEPPEAPQGCLSPSDLLSEPAALQGTQ DWSS Sbjct: 617 LDRVREALQKVRPQQEDEWVNVQYPDQPEEPPEAPQGCLSPSDLLSEPAALQGTQFDWSS 676 Query: 243 AQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILP 302 AQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILP Sbjct: 677 AQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILP 736 Query: 303 DTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLDEN 362 DTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLDEN Sbjct: 737 DTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLDEN 796 Query: 363 CQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYC 422 CQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYC Sbjct: 797 CQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYC 856 Query: 423 DICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMH 482 DICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMH Sbjct: 857 DICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMH 916 Query: 483 LIGRRREQLKLLGDYLGLCRSGALKELSKRAGPESASLKTASSILAAVLPEPGLLRARVC 542 LIGRRREQLKLLGDYLGLCRSGALKELSKR + L++ A Sbjct: 917 LIGRRREQLKLLGDYLGLCRSGALKELSKRLNHRNYLLESPHRFSVA------------D 964 Query: 543 LEQVPRG-SQGVVKSL---GSGGALSPSLVKEPGTCTGMQTCVD---------QMPVGCA 589 L+Q+ G +G +K+L S L + G Q C V CA Sbjct: 965 LQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFI--CQICQHHDIIFPFEFDTTVRCA 1022 Query: 590 ECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA 623 ECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA Sbjct: 1023 ECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA 1056 >gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo sapiens] Length = 528 Score = 877 bits (2267), Expect = 0.0 Identities = 450/529 (85%), Positives = 460/529 (86%), Gaps = 19/529 (3%) Query: 93 GLSNPFRGLMKLGTVERRGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG 152 GLSNPF+GLMKLGTVER+GAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG Sbjct: 10 GLSNPFQGLMKLGTVERQGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVG 69 Query: 153 PAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQEDEWVNVQYSDQPEE 212 PAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQEDEWVNVQYSDQPEE Sbjct: 70 PAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQQEDEWVNVQYSDQPEE 129 Query: 213 PPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPEPDAIKESLLYLYMDRTWMPYIFSLS 272 PPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPE DAIKESLLYLYMDRTWMPYIFSL Sbjct: 130 PPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPELDAIKESLLYLYMDRTWMPYIFSLP 189 Query: 273 LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA 332 LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA Sbjct: 190 LEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAA 249 Query: 333 LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS 392 LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS Sbjct: 250 LWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDS 309 Query: 393 QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA 452 QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA Sbjct: 310 QGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQA 369 Query: 453 LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKR 512 LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGR REQLKLLGDYLGLCRSGALKELSKR Sbjct: 370 LKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELSKR 429 Query: 513 AGPESASLKTASSILAAVLPEPGLLRARVCLEQVPRGSQGVVKSLGSGGALSPSLVKEPG 572 + L++ A L R ++V G + S L + Sbjct: 430 LNHRNYLLESPHRFRVADL--------RQIADEVYEGFLKALIEFASQHVYHCDLCTQRS 481 Query: 573 TCTGMQTCVD---------QMPVGCAECKTVFHQSCQAVVKKGCPRCAR 612 Q C V CA+CKTVFHQSCQAVVKKGCPRCAR Sbjct: 482 FI--CQICQHHDIIFPSEFDTTVRCAKCKTVFHQSCQAVVKKGCPRCAR 528 >gi|122937347 pleckstrin homology domain containing, family M, member 3 [Homo sapiens] Length = 761 Score = 173 bits (438), Expect = 5e-43 Identities = 155/557 (27%), Positives = 243/557 (43%), Gaps = 60/557 (10%) Query: 98 FRGLMKLGTVE-RRGAMGIWKELFCELSPLEFRLYL--SNEEHTCVENCSLLRCESVGP- 153 F ++K G +E R+ W+ + ELSP Y S+ L +S+ Sbjct: 209 FPNILKKGYLEIRKDHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVL 268 Query: 154 AHSDGRF--ELVFSGKKLALRASSQDEAEDW----LDLVREALQKVRPQQEDEWVNV--- 204 + + R +++ +L L+A S EA DW ++V A+ +Q + ++ Sbjct: 269 GNLEARMVDTVLYDNTQLQLKAESPWEALDWGQKLWEVVHAAVPGYMGRQNELTISPGLG 328 Query: 205 QYSD--QPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPEPDAIKESLLY-LYMD 261 + D Q + G L PS +L Q + +K LY L + Sbjct: 329 HHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQ--------------NILKSGTLYRLTVQ 374 Query: 262 RTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVL 321 W + F LS L F+ ++ S+ V+ + D G S F++I + VL Sbjct: 375 NNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVL 434 Query: 322 KLQAGNAEEAALWRDLVRKVLASYLETAEE--AVTLGGS-LDENCQEVLKFATREN--GF 376 +L+A + A W + + K+ A+ ++E+ VTL D+ L+ R++ Sbjct: 435 RLRAETRQRAQEWMEAL-KIAANVARSSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTS 493 Query: 377 LLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPAR 436 L L + +E+GL +Q CAGC R IG S + K+C +SG YYC CH DD+ +IPAR Sbjct: 494 FLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPAR 553 Query: 437 IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGD 496 I+HNWD +K + +QA +FL + +PLI++Q NA LY H E + + R R++LK L Sbjct: 554 IVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRA 613 Query: 497 YLGLCRSGALKELSKRAGPESASLKTASSILAAVLPEPGLLRARVCLEQVPRGS----QG 552 YL CR+ ++L +R P L+ L + L+QV G G Sbjct: 614 YLFSCRAAVAEDLRRRIFPREYLLQQIH------------LYSLADLQQVIEGKLAPFLG 661 Query: 553 VVKSLGSGGALSPSLVKEPG----TCTG---MQTCVDQMPVGCAECKTVFHQSCQAVVKK 605 V + S SL + G C + D C C VFH C+ Sbjct: 662 KVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKE-KSV 720 Query: 606 GCPRCARRRKYQEQNIF 622 CPRC RR ++Q F Sbjct: 721 PCPRCVRRELQKKQKSF 737 >gi|46447820 differentially expressed in FDCP 8 isoform 1 [Homo sapiens] Length = 512 Score = 102 bits (253), Expect = 1e-21 Identities = 77/260 (29%), Positives = 121/260 (46%), Gaps = 32/260 (12%) Query: 379 QYLVAIPMEKGLDSQGCFCAGCSRQIGFSFV--RPKLCAFSGLYYCDICHQDDASVIPAR 436 +Y + I E GLDSQ CA C I V + C ++G YYC CH +D +VIPAR Sbjct: 260 EYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPAR 319 Query: 437 IIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGD 496 ++HNWD R + R ++++L + ++P++ L+ +N L+ +VE + I + R+ + L+ Sbjct: 320 VVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKP 379 Query: 497 YLGLCRSG----ALKELSKR----AGPESASLKTASSI----LAAVLPEPGLLRAR-VCL 543 Y CR L +L R E S++ + L L E L A+ + L Sbjct: 380 YFITCREAMEARLLLQLQDRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKL 439 Query: 544 EQVPRGSQGVVKSL-GSGGALSPSLVKEPGTCTGMQTCVDQMPVGCAECKTVFHQSCQAV 602 + ++G V L G L P D CA+C VFH+ C Sbjct: 440 DCERCQAKGFVCELCREGDVLFP---------------FDSHTSVCADCSAVFHRDCYYD 484 Query: 603 VKKGCPRCARRRKYQEQNIF 622 CP+CA R ++Q++F Sbjct: 485 NSTTCPKCA-RLSLRKQSLF 503 >gi|156151402 hypothetical protein LOC80183 [Homo sapiens] Length = 662 Score = 91.3 bits (225), Expect = 2e-18 Identities = 84/287 (29%), Positives = 122/287 (42%), Gaps = 26/287 (9%) Query: 350 EEAVTLGGSLDENCQEVLKFATRENG--------FLLQYLVAIPMEKGL--DSQGCFCAG 399 EE V N + +KF +R G F + + + P+++ L +Q FCAG Sbjct: 377 EECVRKDFESSMNVVQEIKFKSRIRGTEDWAPPRFQIIFNIHPPLKRDLVVAAQNFFCAG 436 Query: 400 CSRQIGFSFV-RPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQ 458 C + FV R + C + G Y+CD CH S IPARI+ WD K + + + L Sbjct: 437 CGTPVEPKFVKRLRYCEYLGKYFCDCCHSYAESCIPARILMMWDFKKYYVSNFSKQLLDS 496 Query: 459 IRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCR--SGALKELSKRAGPE 516 I QP+ NL + SLY + + + +EQL + L CR + ALKE + G Sbjct: 497 IWHQPIFNLLSIGQSLYAKAKELDRVKEIQEQLFHIKKLLKTCRFANSALKEFEQVPGHL 556 Query: 517 SASLKTASSILAAVLPEPGLLRARVCLEQVPRGSQGVVK--SLGSGGALSPSLVKEPGTC 574 + L S+ V + GLL L+ + + S V L G + Sbjct: 557 TDELH-LFSLEDLVRIKKGLLAP--LLKDILKASLAHVAGCELCQGKGFICEFCQNTTVI 613 Query: 575 TGMQTCVDQMPVGCAECKTVFHQSCQAVVKKGCPRCAR---RRKYQE 618 QT + C+ C+ FH+ C CPRCAR RRK E Sbjct: 614 FPFQTATCRR---CSACRACFHKQC--FQSSECPRCARITARRKLLE 655 >gi|224548938 hypothetical protein LOC9711 isoform 1 [Homo sapiens] Length = 927 Score = 68.9 bits (167), Expect = 1e-11 Identities = 61/233 (26%), Positives = 97/233 (41%), Gaps = 24/233 (10%) Query: 397 CAGCSRQIGFSFV-RPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKF 455 CAGC + ++ R + C + G Y+C CH++ IP+R++ WD +K + + Sbjct: 676 CAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDL 735 Query: 456 LTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKRAG- 514 L +I PL N+Q +N++LY V+ ++ + R QL + + CR KEL Sbjct: 736 LIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCR--LAKELLDSFDT 793 Query: 515 -----PESASLKTASSILAAVLPEPGLLRA---RVCLEQVPRGSQGVVKSLGSGGALSPS 566 E L + + + A E G A R V R K + Sbjct: 794 VPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNED 853 Query: 567 LVKEPGTCTGMQTCVDQMPVGCAECKTVFHQSCQAVVKKG-CPRCARRRKYQE 618 + P +T C ECK +H++C K G CPRC R + +E Sbjct: 854 DIIFPFELHKCRT--------CEECKACYHKAC---FKSGSCPRCERLQARRE 895 >gi|150456467 hypothetical protein LOC9711 isoform 2 [Homo sapiens] Length = 972 Score = 68.9 bits (167), Expect = 1e-11 Identities = 61/233 (26%), Positives = 97/233 (41%), Gaps = 24/233 (10%) Query: 397 CAGCSRQIGFSFV-RPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKF 455 CAGC + ++ R + C + G Y+C CH++ IP+R++ WD +K + + Sbjct: 721 CAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDL 780 Query: 456 LTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKRAG- 514 L +I PL N+Q +N++LY V+ ++ + R QL + + CR KEL Sbjct: 781 LIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCR--LAKELLDSFDT 838 Query: 515 -----PESASLKTASSILAAVLPEPGLLRA---RVCLEQVPRGSQGVVKSLGSGGALSPS 566 E L + + + A E G A R V R K + Sbjct: 839 VPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNED 898 Query: 567 LVKEPGTCTGMQTCVDQMPVGCAECKTVFHQSCQAVVKKG-CPRCARRRKYQE 618 + P +T C ECK +H++C K G CPRC R + +E Sbjct: 899 DIIFPFELHKCRT--------CEECKACYHKAC---FKSGSCPRCERLQARRE 940 >gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 isoform d [Homo sapiens] Length = 1133 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/124 (25%), Positives = 62/124 (50%), Gaps = 6/124 (4%) Query: 93 GLSNPFRGLMKLGTVERRGAMG--IWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCES 150 G S P ++K G +++ G I+++ + L R + SN++ S+ C S Sbjct: 75 GGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVA-CIS 133 Query: 151 VGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREAL--QKVRPQQEDEW-VNVQYS 207 A D +FE++ + + A RA S E ++W+ +++A+ Q+ R + + + V S Sbjct: 134 HVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGS 193 Query: 208 DQPE 211 +QP+ Sbjct: 194 EQPD 197 >gi|206597513 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 isoform a [Homo sapiens] Length = 1205 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/124 (25%), Positives = 62/124 (50%), Gaps = 6/124 (4%) Query: 93 GLSNPFRGLMKLGTVERRGAMG--IWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCES 150 G S P ++K G +++ G I+++ + L R + SN++ S+ C S Sbjct: 75 GGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVA-CIS 133 Query: 151 VGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREAL--QKVRPQQEDEW-VNVQYS 207 A D +FE++ + + A RA S E ++W+ +++A+ Q+ R + + + V S Sbjct: 134 HVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGS 193 Query: 208 DQPE 211 +QP+ Sbjct: 194 EQPD 197 >gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 isoform c [Homo sapiens] Length = 1450 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/124 (25%), Positives = 62/124 (50%), Gaps = 6/124 (4%) Query: 93 GLSNPFRGLMKLGTVERRGAMG--IWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCES 150 G S P ++K G +++ G I+++ + L R + SN++ S+ C S Sbjct: 320 GGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLRYFDSNKDAYSKRFISVA-CIS 378 Query: 151 VGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREAL--QKVRPQQEDEW-VNVQYS 207 A D +FE++ + + A RA S E ++W+ +++A+ Q+ R + + + V S Sbjct: 379 HVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAMAEQRARARLSSAYLLGVPGS 438 Query: 208 DQPE 211 +QP+ Sbjct: 439 EQPD 442 >gi|150456471 doublecortin domain containing 2B [Homo sapiens] Length = 349 Score = 36.6 bits (83), Expect = 0.071 Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 2/71 (2%) Query: 198 EDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEP--AALQGTQSDWSSAQVPEPDAIKESL 255 EDE+ ++ Y + P P+GC P S P QG ++ + EPD IK S Sbjct: 202 EDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSA 261 Query: 256 LYLYMDRTWMP 266 Y +T P Sbjct: 262 FYARPQQTIQP 272 >gi|158631203 dual adaptor of phosphotyrosine and 3-phosphoinositides [Homo sapiens] Length = 280 Score = 36.2 bits (82), Expect = 0.093 Identities = 37/162 (22%), Positives = 65/162 (40%), Gaps = 14/162 (8%) Query: 45 RHFSQEPRKNCSLGALDQACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSN-------P 97 +HF+ +P G L P P + + + ++S RV Q G + P Sbjct: 107 KHFANQPLIGSETGTLMVLKHPYPRKVEEPSI----YESVRVHTAMQTGRTEDDLVPTAP 162 Query: 98 FRGLMKLGTVERRGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSD 157 G + ++ G + WK + L E + + + L C +V +S Sbjct: 163 SLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQ 222 Query: 158 GR---FELVFSGKKLALRASSQDEAEDWLDLVREALQKVRPQ 196 R F LVF + L A + EA++W+ ++R L ++R Q Sbjct: 223 ERVNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQIRKQ 264 >gi|50083291 amyloid beta A4 precursor protein-binding, family B, member 2 [Homo sapiens] Length = 736 Score = 34.7 bits (78), Expect = 0.27 Identities = 23/93 (24%), Positives = 34/93 (36%), Gaps = 14/93 (15%) Query: 177 DEAEDWLDLVREALQKVRPQQEDEWVNVQYSDQPEEPP--------------EAPQGCLS 222 DE W L +++ P + D W + + P+ PP P G Sbjct: 257 DEESSWTTLSQDSASPSSPDETDIWSDHSFQTDPDLPPGWKRVSDIAGTYYWHIPTGTTQ 316 Query: 223 PSDLLSEPAALQGTQSDWSSAQVPEPDAIKESL 255 +S PA LQG++ S+ P P E L Sbjct: 317 WERPVSIPADLQGSRKGSLSSVTPSPTPENEDL 349 >gi|5174547 mitogen-activated protein kinase kinase kinase 5 [Homo sapiens] Length = 1374 Score = 34.7 bits (78), Expect = 0.27 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 7/93 (7%) Query: 190 LQKVRPQQEDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPEPD 249 L + +++ E +++ QP E PE P L+ S +E + L +DW + D Sbjct: 1270 LHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSSGTNTEDSEL----TDWLRVNGADED 1325 Query: 250 AIKESLLYLYMDRTWMPYIFSLSLEALKCFRIR 282 I +L D T + ++ ++ + LKC R+R Sbjct: 1326 TISR---FLAEDYTLLDVLYYVTRDDLKCLRLR 1355 >gi|38787957 tensin like C1 domain containing phosphatase isoform 2 [Homo sapiens] Length = 1409 Score = 33.9 bits (76), Expect = 0.46 Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 569 KEPGTCTGMQTCVDQMPVGCAECKTVFHQSCQAVVKKGC 607 K+P C + +D V C CK H+ C+A V C Sbjct: 41 KKPPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSAC 79 >gi|38787941 tensin like C1 domain containing phosphatase isoform 1 [Homo sapiens] Length = 1419 Score = 33.9 bits (76), Expect = 0.46 Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 569 KEPGTCTGMQTCVDQMPVGCAECKTVFHQSCQAVVKKGC 607 K+P C + +D V C CK H+ C+A V C Sbjct: 51 KKPPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSAC 89 >gi|33457316 pleckstrin homology domain containing, family O member 2 [Homo sapiens] Length = 490 Score = 33.9 bits (76), Expect = 0.46 Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 8/98 (8%) Query: 111 GAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSL---LRCESV-GPAHSDGRFELVFS- 165 G +G WK+ + L + +Y + ++ CVE L +C+ + RF L+ S Sbjct: 31 GLLGFWKDRYLLLCQAQLLVYENEDDQKCVETVELGSYEKCQDLRALLKRKHRFILLRSP 90 Query: 166 GKKLA---LRASSQDEAEDWLDLVREALQKVRPQQEDE 200 G K++ +A + +E E W+ + E + + + + DE Sbjct: 91 GNKVSDIKFQAPTGEEKESWIKALNEGINRGKNKAFDE 128 >gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] Length = 1863 Score = 33.5 bits (75), Expect = 0.60 Identities = 26/68 (38%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Query: 506 LKELSKRAGPESASLK-TASSILAAVLPEPGLL-RARVCLEQVPRGSQGVVKSLGSGGAL 563 +K+ S GPE L T + AV PE L R RV L+ P S+ V K LG+ Sbjct: 1148 IKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATF 1207 Query: 564 SPSLVKEP 571 SP + EP Sbjct: 1208 SPIVTLEP 1215 >gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] Length = 1872 Score = 33.5 bits (75), Expect = 0.60 Identities = 26/68 (38%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Query: 506 LKELSKRAGPESASLK-TASSILAAVLPEPGLL-RARVCLEQVPRGSQGVVKSLGSGGAL 563 +K+ S GPE L T + AV PE L R RV L+ P S+ V K LG+ Sbjct: 1157 IKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATF 1216 Query: 564 SPSLVKEP 571 SP + EP Sbjct: 1217 SPIVTLEP 1224 >gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] Length = 3957 Score = 33.5 bits (75), Expect = 0.60 Identities = 26/68 (38%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Query: 506 LKELSKRAGPESASLK-TASSILAAVLPEPGLL-RARVCLEQVPRGSQGVVKSLGSGGAL 563 +K+ S GPE L T + AV PE L R RV L+ P S+ V K LG+ Sbjct: 1157 IKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATF 1216 Query: 564 SPSLVKEP 571 SP + EP Sbjct: 1217 SPIVTLEP 1224 >gi|7662230 ring finger protein 40 [Homo sapiens] Length = 1001 Score = 33.1 bits (74), Expect = 0.78 Identities = 33/122 (27%), Positives = 46/122 (37%), Gaps = 7/122 (5%) Query: 132 LSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREALQ 191 LS EE T +R + L F KKLA R + ED L RE ++ Sbjct: 22 LSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLAERLEQRQACEDEL---RERIE 78 Query: 192 KVRPQQEDEWVNV----QYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPE 247 K+ +Q + + +Y Q +E EA C LS GTQ + P Sbjct: 79 KLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSSAPEAPGTQEGPTCDGTPL 138 Query: 248 PD 249 P+ Sbjct: 139 PE 140 >gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] Length = 1544 Score = 32.3 bits (72), Expect = 1.3 Identities = 41/141 (29%), Positives = 61/141 (43%), Gaps = 20/141 (14%) Query: 483 LIGRRREQLKLLGDYL-GLCRSGALKELSKRAGPESASLKTASSILAAVLPEPGLLRARV 541 L+G +R+Q KL G +S L+ LS + S +TAS++ A L E LR Sbjct: 1098 LLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETASAM--ATLGE-ARLREME 1154 Query: 542 CLEQVPRGSQGVVKSLGSGGALSPSLVKEPGTCTGMQTCVDQMPVGCAECKTVFHQSCQA 601 L+ + ++G + LSP + C + M + C C+ FH SC A Sbjct: 1155 ALQSLRLANEGKL--------LSPLQDVDIKICLCQKAPAAPM-IQCELCRDAFHTSCVA 1205 Query: 602 V--VKKG-----CPRCARRRK 615 V + +G CP C R K Sbjct: 1206 VPSISQGLRIWLCPHCRRSEK 1226 >gi|32967599 ankyrin 3 isoform 2 [Homo sapiens] Length = 1001 Score = 32.3 bits (72), Expect = 1.3 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Query: 506 LKELSKRAGPESASLK-TASSILAAVLPEPGLL-RARVCLEQVPRGSQGVVKSLGSGGAL 563 +K+ S + GPE L T ++ A PE L R RV L+ P + V K LG+ Sbjct: 274 IKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKILGNKATF 333 Query: 564 SPSLVKEP 571 SP + EP Sbjct: 334 SPIVTVEP 341 >gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] Length = 4377 Score = 32.3 bits (72), Expect = 1.3 Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Query: 506 LKELSKRAGPESASLK-TASSILAAVLPEPGLL-RARVCLEQVPRGSQGVVKSLGSGGAL 563 +K+ S + GPE L T ++ A PE L R RV L+ P + V K LG+ Sbjct: 1140 IKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKILGNKATF 1199 Query: 564 SPSLVKEP 571 SP + EP Sbjct: 1200 SPIVTVEP 1207 >gi|21264592 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [Homo sapiens] Length = 1704 Score = 32.3 bits (72), Expect = 1.3 Identities = 15/61 (24%), Positives = 28/61 (45%) Query: 131 YLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDLVREAL 190 Y +NE+ + L S D +FE+V + + R ++E DW+ ++ AL Sbjct: 514 YYNNEKEMYSKGIIPLSAISTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNAL 573 Query: 191 Q 191 + Sbjct: 574 K 574 >gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens] Length = 1291 Score = 32.0 bits (71), Expect = 1.7 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 4/51 (7%) Query: 160 FELVFSGKKLALRASSQDEAEDWLD----LVREALQKVRPQQEDEWVNVQY 206 + + F K L+L+A+S+DE W+ L+ + LQ P Q + W+ Q+ Sbjct: 111 YGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQF 161 >gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens] Length = 1290 Score = 32.0 bits (71), Expect = 1.7 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 4/51 (7%) Query: 160 FELVFSGKKLALRASSQDEAEDWLD----LVREALQKVRPQQEDEWVNVQY 206 + + F K L+L+A+S+DE W+ L+ + LQ P Q + W+ Q+ Sbjct: 111 YGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQF 161 >gi|14249672 protein phosphatase 1, regulatory (inhibitor) subunit 16A [Homo sapiens] Length = 528 Score = 32.0 bits (71), Expect = 1.7 Identities = 34/104 (32%), Positives = 44/104 (42%), Gaps = 17/104 (16%) Query: 482 HLIGRRREQLKLLGDYLGLCRSGALKELSKRAGPESASLKTASS--ILAAVLPEPGLLRA 539 H RR +Q+K+ A KE + GP K A+S +L VL P + Sbjct: 25 HAQKRRAQQVKMWAQ--------AEKEAQGKKGPGERPRKEAASQGLLKQVLFPPSV--- 73 Query: 540 RVCLEQVPRGSQGVVKS-LGSGGALSPSLVKEPGTCTGMQTCVD 582 V LE R V+ LGSG +SP L E G Q C+D Sbjct: 74 -VLLEAAARNDLEEVRQFLGSG--VSPDLANEDGLTALHQCCID 114 >gi|116805330 small conductance calcium-activated potassium channel protein 3 isoform a [Homo sapiens] Length = 731 Score = 31.2 bits (69), Expect = 3.0 Identities = 19/53 (35%), Positives = 23/53 (43%), Gaps = 1/53 (1%) Query: 196 QQEDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEPAALQGTQSDWSSAQVPEP 248 QQ+ + Q P PP APQ L PS L +P LQ Q Q +P Sbjct: 30 QQQQQQQQQQQQPPPPAPPAAPQQPLGPS-LQPQPPQLQQQQQQQQQQQQQQP 81 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.134 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,170,941 Number of Sequences: 37866 Number of extensions: 1287524 Number of successful extensions: 4432 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 4379 Number of HSP's gapped (non-prelim): 81 length of query: 623 length of database: 18,247,518 effective HSP length: 108 effective length of query: 515 effective length of database: 14,157,990 effective search space: 7291364850 effective search space used: 7291364850 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.