Guide to the Human Genome
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Name: MAP3K5 Sequence: fasta or formatted (1374aa) NCBI GI: 5174547
Description:

mitogen-activated protein kinase kinase kinase 5

Referenced in:

MAP Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.3         86           3
 C cysteine            1.7         23           2
 D aspartate           6.0         82           2
 E glutamate           8.1        111           2
 F phenylalanine       4.7         65           2
 G glycine             5.7         79           3
 H histidine           2.6         36           3
 I isoleucine          6.1         84           2
 K lysine              6.4         88           4
 L leucine            10.3        141           3
 M methionine          1.8         25           1
 N asparagine          3.5         48           2
 P proline             4.3         59           5
 Q glutamine           3.6         49           1
 R arginine            4.9         67           2
 S serine              8.3        114           4
 T threonine           5.6         77           2
 V valine              6.3         87           2
 W tryptophan          0.9         13           1
 Y tyrosine            2.9         40           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mitogen-activated protein kinase kinase kinase 5 [Hom... 
MAP3K6                0.397   mitogen-activated protein kinase kinase kinase 6 [Ho...
MAP3K15               0.310   mitogen-activated protein kinase kinase kinase 15 [...
YSK4                  0.062   Yeast Sps1/Ste20-related kinase 4 isoform 1 
YSK4                  0.062   Yeast Sps1/Ste20-related kinase 4 isoform 2 
MAP3K3                0.053   mitogen-activated protein kinase kinase kinase 3 iso...
MAP3K3                0.053   mitogen-activated protein kinase kinase kinase 3 iso...
MAP3K4                0.051   mitogen-activated protein kinase kinase kinase 4 iso...
MAP3K4                0.051   mitogen-activated protein kinase kinase kinase 4 iso...
MAP3K1                0.051   mitogen-activated protein kinase kinase kinase 1 [H...
MAP3K2                0.050   mitogen-activated protein kinase kinase kinase 2 [Ho...
PAK1                  0.045   p21-activated kinase 1 isoform 2 
PAK3                  0.044   p21-activated kinase 3 isoform d 
PAK3                  0.044   p21-activated kinase 3 isoform c 
PAK3                  0.044   p21-activated kinase 3 isoform b 
PAK3                  0.044   p21-activated kinase 3 isoform a 
PAK3                  0.044   p21-activated kinase 3 isoform a 
PAK3                  0.044   p21-activated kinase 3 isoform a 
PAK2                  0.043   p21-activated kinase 2 
STK3                  0.043   serine/threonine kinase 3 
STK4                  0.042   serine/threonine kinase 4 
SLK                   0.042   serine/threonine kinase 2 
MST4                  0.042   serine/threonine protein kinase MST4 isoform 1 [Homo...
STK24                 0.042   serine/threonine kinase 24 isoform b 
STK24                 0.042   serine/threonine kinase 24 isoform a 
PAK1                  0.041   p21-activated kinase 1 isoform 1 
NEK5                  0.041   NIMA-related kinase 5 
PLK2                  0.041   polo-like kinase 2 
STK25                 0.040   serine/threonine kinase 25 
MAP4K3                0.039   mitogen-activated protein kinase kinase kinase kinas...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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