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Search of human proteins with 239756568
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239756568 PREDICTED: similar to BCL2-associated
transcription factor 1 [Homo sapiens]
(869 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239756568 PREDICTED: similar to BCL2-associated transcription... 1749 0.0
gi|169218320 PREDICTED: similar to BCL2-associated transcription... 1741 0.0
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H... 1713 0.0
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom... 1685 0.0
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H... 695 0.0
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 424 e-118
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 105 2e-22
gi|115511057 hypothetical protein LOC256643 [Homo sapiens] 101 3e-21
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 98 4e-20
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 90 8e-18
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 88 4e-17
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 88 4e-17
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 86 1e-16
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 85 3e-16
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 84 6e-16
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 84 7e-16
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 82 3e-15
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 82 3e-15
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 81 5e-15
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 81 5e-15
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 81 5e-15
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 80 6e-15
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 80 1e-14
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 80 1e-14
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 77 7e-14
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 77 9e-14
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 76 2e-13
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 73 1e-12
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 73 1e-12
gi|52426743 cisplatin resistance-associated overexpressed protei... 72 2e-12
>gi|239756568 PREDICTED: similar to BCL2-associated transcription
factor 1 [Homo sapiens]
Length = 869
Score = 1749 bits (4530), Expect = 0.0
Identities = 869/869 (100%), Positives = 869/869 (100%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS
Sbjct: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
Query: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSK 180
QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSK
Sbjct: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSK 180
Query: 181 SQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSC 240
SQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYD SPRSPHSPSPIATPPSQSSSC
Sbjct: 181 SQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSC 240
Query: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA
Sbjct: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
Query: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK
Sbjct: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
Query: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS
Sbjct: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
Query: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEED 480
FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEED
Sbjct: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEED 480
Query: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS
Sbjct: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
Query: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS
Sbjct: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
Query: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
ESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL
Sbjct: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
Query: 661 RKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRK 720
RKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRK
Sbjct: 661 RKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRK 720
Query: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
QEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHE
Sbjct: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
Query: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDK 840
MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDK
Sbjct: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDK 840
Query: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869
YQGDGIVEDEEETMENNEEKKDRCKEEKE
Sbjct: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869
>gi|169218320 PREDICTED: similar to BCL2-associated transcription
factor 1 isoform 2 [Homo sapiens]
Length = 869
Score = 1741 bits (4508), Expect = 0.0
Identities = 865/869 (99%), Positives = 865/869 (99%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS
Sbjct: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
Query: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSK 180
QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE QEESPLKSK
Sbjct: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 180
Query: 181 SQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSC 240
SQEEPKDTFEHD SESIDEFNKSSAT GDIWPGLSAYD SPRSPHSPSPIATPPSQSSSC
Sbjct: 181 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC 240
Query: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA
Sbjct: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
Query: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK
Sbjct: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
Query: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS
Sbjct: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
Query: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEED 480
FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEED
Sbjct: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEED 480
Query: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS
Sbjct: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
Query: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS
Sbjct: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
Query: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
ESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL
Sbjct: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
Query: 661 RKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRK 720
RKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRK
Sbjct: 661 RKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRK 720
Query: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
QEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHE
Sbjct: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
Query: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDK 840
MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDK
Sbjct: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDK 840
Query: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869
YQGDGIVEDEEETMENNEEKKDRCKEEKE
Sbjct: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869
>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
sapiens]
Length = 869
Score = 1713 bits (4436), Expect = 0.0
Identities = 855/869 (98%), Positives = 856/869 (98%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
NNR MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS
Sbjct: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
Query: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSK 180
QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE QEESPLKSK
Sbjct: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 180
Query: 181 SQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSC 240
SQEEPKDTFEHD SESIDEFNKSSAT GDIWPGLSAYD SPRSPHSPSPIATPPSQSSSC
Sbjct: 181 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC 240
Query: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA
Sbjct: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
Query: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK
Sbjct: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
Query: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS
Sbjct: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
Query: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEED 480
FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN K KETGYVVERPSTTKDKHKEED
Sbjct: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEED 480
Query: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS
Sbjct: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
Query: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS
Sbjct: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
Query: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
ESFIQHIVSLVHHVKEQYFKSAAMTL+ERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL
Sbjct: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
Query: 661 RKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRK 720
RK TRLAGEERVFKEENQKGDKKLRCDSADLRHDID RRKERSKERGDSKGSRES GSRK
Sbjct: 661 RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRK 720
Query: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
QEKTPKDYKEYKSYKDDSKHKREQDHS SSSSSASPSSPSSREEKESKKEREEEFKTHHE
Sbjct: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
Query: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDK 840
MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKW HDK
Sbjct: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDK 840
Query: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869
YQGDGIVEDEEETMENNEEKKDR KEEKE
Sbjct: 841 YQGDGIVEDEEETMENNEEKKDRRKEEKE 869
>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
sapiens]
Length = 920
Score = 1685 bits (4363), Expect = 0.0
Identities = 855/920 (92%), Positives = 856/920 (93%), Gaps = 51/920 (5%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY RSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
Query: 59 YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118
YRNNR MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLK 178
SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE QEESPLK
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
Query: 179 SKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSS 238
SKSQEEPKDTFEHD SESIDEFNKSSAT GDIWPGLSAYD SPRSPHSPSPIATPPSQSS
Sbjct: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
Query: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298
SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
Query: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 358
PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
Sbjct: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 360
Query: 359 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 418
SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
Sbjct: 361 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 420
Query: 419 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKE 478
KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN K KETGYVVERPSTTKDKHKE
Sbjct: 421 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE 480
Query: 479 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 538
EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
Sbjct: 481 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 540
Query: 539 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 598
DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
Sbjct: 541 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 600
Query: 599 TSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658
TSESFIQHIVSLVHHVKEQYFKSAAMTL+ERFTSYQKATEEHSTRQKSPEIHRRIDISPS
Sbjct: 601 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660
Query: 659 TLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGS 718
TLRK TRLAGEERVFKEENQKGDKKLRCDSADLRHDID RRKERSKERGDSKGSRES GS
Sbjct: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720
Query: 719 RKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTH 778
RKQEKTPKDYKEYKSYKDDSKHKREQDHS SSSSSASPSSPSSREEKESKKEREEEFKTH
Sbjct: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
Query: 779 HEMKEYSGFAGVSRPRGTF----------------------------------------- 797
HEMKEYSGFAGVSRPRGTF
Sbjct: 781 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT 840
Query: 798 --------HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVED 849
HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKW HDKYQGDGIVED
Sbjct: 841 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 900
Query: 850 EEETMENNEEKKDRCKEEKE 869
EEETMENNEEKKDR KEEKE
Sbjct: 901 EEETMENNEEKKDRRKEEKE 920
>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
sapiens]
Length = 747
Score = 695 bits (1793), Expect = 0.0
Identities = 412/741 (55%), Positives = 463/741 (62%), Gaps = 112/741 (15%)
Query: 235 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS------------------------ 270
S+S S S + S HS K S S S +S RS
Sbjct: 13 SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72
Query: 271 ----GSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP--------RDESRGRSS 318
G G G RY P+ + RSP + + +P R SR R S
Sbjct: 73 YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132
Query: 319 FYPDGGDQETAKTGK-------FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEG 371
+ + ++ KR +E + + G +++ K K E+ +
Sbjct: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE-GEPQEESPLKSKSQEEPKDTF 191
Query: 372 EWEDQEALDYFSDKES-------GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 424
E + E++D F+ + G +++S + +S +T
Sbjct: 192 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 251
Query: 425 -SHRNTEEE---GLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKD---KHK 477
S +NT + +++ + S G+ +G ++ ++ R S K ++
Sbjct: 252 HSAKNTPSQHSHSIQHSPERSGSGS-VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNA 310
Query: 478 EEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIA 537
D++ R + + E K+ K F SPPLHKNLDAREKSTFREESPLRIKMIA
Sbjct: 311 PRDESRGRSSFYPDGGDQETAKTGK----FLKSPPLHKNLDAREKSTFREESPLRIKMIA 366
Query: 538 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK 597
SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK
Sbjct: 367 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK 426
Query: 598 STSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISP 657
STSESFIQHIVSLVHHVKEQYFKSAAMTL+ERFTSYQKATEEHSTRQKSPEIHRRIDISP
Sbjct: 427 STSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISP 486
Query: 658 STLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRG 717
STLRK TRLAGEERVFKEENQKGDKKLRCDSADLRHDID RRKERSKERGDSKGSRES G
Sbjct: 487 STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSG 546
Query: 718 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKT 777
SRKQEKTPKDYKEYKSYKDDSKHKREQDHS SSSSSASPSSPSSREEKESKKEREEEFKT
Sbjct: 547 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT 606
Query: 778 HHEMKEYSGFAGVSRPRGTF---------------------------------------- 797
HHEMKEYSGFAGVSRPRGTF
Sbjct: 607 HHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY 666
Query: 798 ---------HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVE 848
HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKW HDKYQGDGIVE
Sbjct: 667 TPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVE 726
Query: 849 DEEETMENNEEKKDRCKEEKE 869
DEEETMENNEEKKDR KEEKE
Sbjct: 727 DEEETMENNEEKKDRRKEEKE 747
Score = 664 bits (1712), Expect = 0.0
Identities = 331/338 (97%), Positives = 331/338 (97%), Gaps = 2/338 (0%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY RSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
Query: 59 YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118
YRNNR MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLK 178
SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE QEESPLK
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
Query: 179 SKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSS 238
SKSQEEPKDTFEHD SESIDEFNKSSAT GDIWPGLSAYD SPRSPHSPSPIATPPSQSS
Sbjct: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
Query: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298
SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
Query: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336
PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK
Sbjct: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338
Score = 42.4 bits (98), Expect = 0.002
Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 25/112 (22%)
Query: 735 KDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEM---------KEYS 785
+ +S+ + S S SSS S S SR+++ S + R + ++Y
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
Query: 786 GFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWN 837
G+ RP G RGRGRG +Q G GR++ + G P WN
Sbjct: 63 NNRGMRRPYGY--------------RGRGRGYYQGGGGRYH--RGGYRPVWN 98
Score = 42.0 bits (97), Expect = 0.002
Identities = 53/230 (23%), Positives = 95/230 (41%), Gaps = 28/230 (12%)
Query: 627 SERFTSYQKATEEHSTRQKSPEIHRRIDISP-STLRKDTRLAGEERVFKEENQKGDKKLR 685
S +S K+ + S+R +S R+ S S R +R +R++ + ++ + R
Sbjct: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 65
Query: 686 CDSADLRHDIDHRRKERSKERG--------------DSKGSRESRGSRKQEKTPKDYKEY 731
+R +R + R +G + + SR R R + ++PK +
Sbjct: 66 ----GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSV 120
Query: 732 KSYKDDSKHKREQDHSLS----SSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGF 787
S + S+ +R S S SS S+SP S S ++ +E++ + K E +E S
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK-KAEGEPQEESPL 179
Query: 788 AGVSR--PRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRF-NFKKSGSSP 834
S+ P+ TF D + +D + K G G + N +S SP
Sbjct: 180 KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229
Score = 35.4 bits (80), Expect = 0.23
Identities = 43/186 (23%), Positives = 78/186 (41%), Gaps = 25/186 (13%)
Query: 10 SSRSKSRSQSSSRSRSRS-HSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA---- 64
+S K+ + S+R +S H R S R ++R +R++ + ++ + R
Sbjct: 460 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSAD 519
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQRS 123
+R R + R +G + + SR R + ++PK + S +
Sbjct: 520 LRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYKD 565
Query: 124 RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQE 183
S+ +R SRS SS+S SS + SK+ +E +T E++E S S+
Sbjct: 566 DSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR- 621
Query: 184 EPKDTF 189
P+ TF
Sbjct: 622 -PRGTF 626
Score = 33.5 bits (75), Expect = 0.88
Identities = 40/195 (20%), Positives = 73/195 (37%), Gaps = 24/195 (12%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
+ +S+ + SRS SSS S S SR+++ + R + + ++Y
Sbjct: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER-------EEEFKTHHEMKEYSGF 616
Query: 63 RAMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGRSR 109
+ RP G RGR RG + G + + W+ + +P+ +
Sbjct: 617 AGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKKYF 674
Query: 110 SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169
+ V R R R +++ R + SSP K K +G + ++
Sbjct: 675 LHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEETM 732
Query: 170 ELQEESPLKSKSQEE 184
E EE + K ++E
Sbjct: 733 ENNEEKKDRRKEEKE 747
Score = 30.4 bits (67), Expect = 7.4
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 20/99 (20%)
Query: 2 GRSNSR---SHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58
GR +R + ++ + S ++ + R + Y +S+ Y RD DY
Sbjct: 631 GRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDD--GVDY--- 685
Query: 59 YRNNRAMRRPYGYRGRGRGYYQGGGGRYH--RGGYRPVW 95
+ RGRGRG +Q G GR++ + G P W
Sbjct: 686 ----------WAKRGRGRGTFQRGRGRFNFKKSGSSPKW 714
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 424 bits (1091), Expect = e-118
Identities = 353/967 (36%), Positives = 486/967 (50%), Gaps = 137/967 (14%)
Query: 2 GRSNSRSHS-SRSKSRSQSSSRSRSRS--HSRKKRY--RSRSRTYSRSRSRDRMYSRDYR 56
G +SRS S SRS+SRS S SRSRSRS SRK+R RSRSR+YS + +R+R + R Y+
Sbjct: 10 GSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQ 69
Query: 57 -RDYR-NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGY---RPVW-NRRHSRSPRRGRSRS 110
RD+R +NR RRPY +RGR RG+Y G +Y+RGGY R W N R + SPRRGRSRS
Sbjct: 70 NRDFRGHNRGYRRPYYFRGRNRGFYPWG--QYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127
Query: 111 RSPKRRSVSSQRSRSRSRRSYRSS--RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 168
RSPKRRS S RSRS SR S +SS RS RSSSSRSSS +S+ SKR+ ++EK++ +
Sbjct: 128 RSPKRRS-PSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186
Query: 169 GELQEESPLKSKSQEEPKDTF------EHDSSESIDEFNKSSATCGDIWPGLSAYDXSPR 222
+ + ++ E + TF + +SES + ++ G + + SPR
Sbjct: 187 SRPSQAAG-DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPR 245
Query: 223 --SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--GSVGNG 278
SP SP+ + + S +P+ +T S + +SG+ G +G
Sbjct: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305
Query: 279 SSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRF 338
S SPS+ SP+ +SP T + + + E S GG A T ++L+
Sbjct: 306 SGSLSPSKKSPVG-----KSPPSTGSTYGSSQKEESAAS-----GG---AAYTKRYLEEQ 352
Query: 339 TDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYFSDKESGKQKFNDSE 396
E + + NT DKE KEKGS + G +G+ + D F+ K ++ F S+
Sbjct: 353 KTENGKDKEQKQTNT-DKEKIKEKGSFSDTGLGDGKMKS----DSFAPKTDSEKPFRGSQ 407
Query: 397 GDDTEETED-----YRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGF 451
+ D F K + DQ K A + ++ K+ SKV + N+ +
Sbjct: 408 SPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKV-IGANKNQE-- 464
Query: 452 REEKNDKHKETGYVVERPSTTKDKHKEE-DKNSERITVKKETQS-----------PEQ-- 497
EEK+ K + G V P K + EE ++ S KKE + PE+
Sbjct: 465 -EEKSGKWE--GLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNF 521
Query: 498 -VKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDD 556
V + K SPP K ++R+K + + P K S + +V ++M D
Sbjct: 522 RVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTG-KSSFSITREAQVNVRMDSFDEDL 580
Query: 557 SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE 616
+ L ++R L LVHS KKEQEFRSIF HI+ Q+ +S SE F QHIV++VHHVKE
Sbjct: 581 ARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKE 640
Query: 617 QYFKSAAMTLSERFTSYQK--ATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFK 674
+F S+ MTL ERFT Y K +E + +KSPEIHRRIDISPST RK E + +
Sbjct: 641 HHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPR 700
Query: 675 EENQKGDKKLRCDSADLRHDIDHRR--KERSKERGDSKGSRESRGS--RKQEKTPKDYKE 730
E K + K + D DLR DI+ R+ KER +RG S+ S +SR S ++ K K
Sbjct: 701 EPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKT 760
Query: 731 YKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHE-----MKEYS 785
+K K KH+R +D S SSSSS+ S EE + E EE T + K++
Sbjct: 761 HKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFV 820
Query: 786 GFA--GVSRPRGTF---------------------------------------------- 797
G + G R RGTF
Sbjct: 821 GPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKY 880
Query: 798 --HDDRD-DGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQG-DGIVEDEEET 853
HDDR+ +G D W RGRGRG F RGRGRF F+KS +SPKW HDK+ G +G +ED+E
Sbjct: 881 YLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESG 940
Query: 854 MENNEEK 860
EN EEK
Sbjct: 941 TENREEK 947
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 105 bits (261), Expect = 2e-22
Identities = 111/340 (32%), Positives = 147/340 (43%), Gaps = 33/340 (9%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKK-RYRSRSRTYSRSRSRDRMYSR----DYR 56
GRS+SRS ++R +SRS++ +R R RS SR R RSRSRT +R RSR R +R R
Sbjct: 560 GRSHSRSPATRGRSRSRTPAR-RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR 618
Query: 57 RDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRSRSPKR 115
R R P R R R + G R R R SR+P RRGRSRSR+P R
Sbjct: 619 TPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR--GRSRSRTPARRGRSRSRTPAR 676
Query: 116 RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS------PYSKSPVSKRRGSQEKQTKKAEG 169
RS S RSR+ +RR SR+PR SRS S +S++P + R + K
Sbjct: 677 RSGRS-RSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR 735
Query: 170 ELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSP 229
Q S S S E K S S+ + + + LS P+
Sbjct: 736 TSQRRSRSNS-SPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQ--- 791
Query: 230 IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSP 289
TPP +S S S P + TP + S S P + S + SR S S +SP
Sbjct: 792 --TPPRRSRSGSSQP-----KAKSRTPPRRSRSSSSPPPKQKSKT----PSRQSHSSSSP 840
Query: 290 IHHIPSRRSP--AKTIAPQNAPRDESRGRSSFYPDGGDQE 327
+ S P +PQ + + R S + D E
Sbjct: 841 HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880
Score = 100 bits (250), Expect = 4e-21
Identities = 109/355 (30%), Positives = 142/355 (40%), Gaps = 48/355 (13%)
Query: 2 GRSNSRSHSSRSKSRSQSSSR--SRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDY 59
GRS SR+ + R +SRS++ +R RSRS + +R RSRSRT R RSR R RR
Sbjct: 656 GRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSL---VRRGR 712
Query: 60 RNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNR-RHSRSPRRGRSRSRSPKRRSV 118
++R +R RGR G + R R R + SP +SR S + RS+
Sbjct: 713 SHSRTPQR------RGRS----GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL 762
Query: 119 SSQRSRSRSRRSYRSSRS-------------PRSSSSRSSSPYSKSPVSKRRGSQEKQTK 165
SS RS+++SR S R S S PR S S SS P +KS RR
Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPP 822
Query: 166 KAEGELQEESPLKSKSQEEPK---DTFEHDSSESIDEFNKSSAT-----CGDIWPGLSAY 217
+ S S PK T S + + N+ S T C + P
Sbjct: 823 PKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELK 882
Query: 218 DXSPR----SPHSPSPI--ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 271
+P S SP + +TPP QS S S +P HS S SP R
Sbjct: 883 SRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVT 942
Query: 272 SGSVGNGSSRYSPSQNSPIHHIP-----SRRSPAKTIAPQNAPRDESRGRSSFYP 321
S + S SP N +P SP + P+ PR G S YP
Sbjct: 943 SRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYP 997
Score = 90.9 bits (224), Expect = 5e-18
Identities = 108/346 (31%), Positives = 142/346 (41%), Gaps = 46/346 (13%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRS-----HSRKKRYRSRSRT-----YSRSRSRDRMY 51
GRS SR+ + R SRS+S RSRS SR + R RSR+ +SRSR+ R
Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR-- 550
Query: 52 SRDYRRDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR 111
R R R R+ R RGR R GR P R SR+P R RSRSR
Sbjct: 551 -RGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR--SRTPARRRSRSRTPTRRRSRSR 607
Query: 112 SPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP-----YSKSPVSKRRGSQEKQTKK 166
+P RR S RSR+ +RR R +RSP SRS SP S+S RRG +T
Sbjct: 608 TPARRGRS--RSRTPARRRSR-TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPA 664
Query: 167 AEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHS 226
G + +P + + + S S S + + G S HS
Sbjct: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS---------HS 715
Query: 227 PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 286
+P S SSS K+ SQ SPE S SSR S S
Sbjct: 716 RTPQRRGRSGSSS---------ERKNKSRTSQRRSRSNSSPEMKKS----RISSRRSRSL 762
Query: 287 NSPIHHIPSRRSPAKTIAPQN-APRDESRGRSSFYPDGGDQETAKT 331
+SP SR S ++++ + P+ +S+ G Q AK+
Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS 808
Score = 88.6 bits (218), Expect = 2e-17
Identities = 106/332 (31%), Positives = 141/332 (42%), Gaps = 33/332 (9%)
Query: 4 SNSRSH--SSRSKSRSQSSSR--SRSRSHSRKKRYRSRSRT-----YSRSRSRDRMYSRD 54
S +RSH + R KS S + SR RSRS + KR RSRSRT +SRSRS SR
Sbjct: 459 SKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRS 518
Query: 55 YRRDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 114
+R R+ R RGR R + G R R R SRS RRGRS SRSP
Sbjct: 519 AQRWGRSRSPQR-----RGRSRSPQRPGWSR-----SRNTQRRGRSRSARRGRSHSRSPA 568
Query: 115 RRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP---YSKSPVSKRRGSQEKQTKKAEGEL 171
R S RSR+ +RR SR+P SRS +P S+S RRG +T A
Sbjct: 569 TRGRS--RSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT-PARRRS 625
Query: 172 QEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIA 231
+ SP++ +S+ S S + G S +P S
Sbjct: 626 RTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSR-SRTPARRSGRSRSR 684
Query: 232 TPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPE---RSGSGSVGNGSSRYSP--SQ 286
TP + S S P S SHS +P+ RSGS S SR S S+
Sbjct: 685 TPARRGRSRSRTPRRGRSRSRSLVRRGRSHS--RTPQRRGRSGSSSERKNKSRTSQRRSR 742
Query: 287 NSPIHHIPSRRSPAKTIAPQNAPRDESRGRSS 318
++ + R ++ ++PR +++ R S
Sbjct: 743 SNSSPEMKKSRISSRRSRSLSSPRSKAKSRLS 774
Score = 65.5 bits (158), Expect = 2e-10
Identities = 110/404 (27%), Positives = 155/404 (38%), Gaps = 83/404 (20%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSR------SRSRDRM-YSRDYRR 57
+SR S S R++++SR R RS S K R RSR+ SR +R RDR S+ R
Sbjct: 1741 SSRRRRSASSPRTKTTSR-RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSR 1799
Query: 58 DYRNNRAMRRPYGYRGRGRGYYQGG---------GGRYHRGGYR-PVWNRRHSRS----- 102
+ +R+ R R G GY+ R RG R P +R+ SRS
Sbjct: 1800 RRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPA 1859
Query: 103 -----------PRRGRSRSRSP---KRRS------VSSQRSRSRSRRSYRSSRSPRSSSS 142
RSRSR+P +RRS VS +RSRSR+ + R SRS S S
Sbjct: 1860 PWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVS 1919
Query: 143 RSSSPYSKSPVSKRRGSQEKQT--KKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEF 200
R S PV++RR T +++ + +S+S+ P S S
Sbjct: 1920 RRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITR 1979
Query: 201 NKSSATCGDIWPGLSAYDXSP----RSPHSPSPIA-------TPPS-QSSSCSDAPMLST 248
+S + + S SP RS SP+ TPP+ + S S P+L
Sbjct: 1980 RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPR 2039
Query: 249 VHSAKNTP--------------SQHSHSIQHSP----ERSGSGSVGNGSSRYSP------ 284
S +P ++ S+ SP RS SGS + S +P
Sbjct: 2040 KRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099
Query: 285 --SQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQ 326
S+ P+ SR S + P D R P G +
Sbjct: 2100 SGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSR 2143
Score = 61.6 bits (148), Expect = 3e-09
Identities = 82/349 (23%), Positives = 132/349 (37%), Gaps = 71/349 (20%)
Query: 16 RSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRAMRRPYGYRGRG 75
R SSSRS + +KK+ + R R S R ++ +R+ ++
Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK-------- 226
Query: 76 RGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSR 135
R HR ++R S+ +R RSRS +P +S + RS S S +
Sbjct: 227 ---------RKHRSPTPK--SKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTS 275
Query: 136 SPRSSSSRSS------SPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTF 189
RS S+ + + S SP S RRG + + + + ++P +
Sbjct: 276 RSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPY 335
Query: 190 EHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSP---------HSPSPIAT-------- 232
E + + SAT P S+ P +P SP P+AT
Sbjct: 336 EDKDKDK----KEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPV 391
Query: 233 -PPSQSSSCSD---------APMLSTVHSAKNTP-----SQHSHSIQHSPE--------R 269
PPS++S D P S+ S+ +P S+H+ S SP+ R
Sbjct: 392 NPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHR 451
Query: 270 SGSGSVGNGSSRYSPSQNSPIH-HIPSRRSPAKTIAPQNAPRDESRGRS 317
S S + + + ++ H H PSRR ++ +P A R SR R+
Sbjct: 452 EISSSPTSKNRSHGRAKRDKSHSHTPSRRM-GRSRSPATAKRGRSRSRT 499
Score = 51.6 bits (122), Expect = 3e-06
Identities = 96/481 (19%), Positives = 167/481 (34%), Gaps = 50/481 (10%)
Query: 96 NRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSK 155
++ HS +P R RSRSP RSR+ ++R + SRSP+ SRS+ + +S +
Sbjct: 470 DKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQ 529
Query: 156 RRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLS 215
RRG + + ++ + + +S+ S+ ++S AT G
Sbjct: 530 RRG-RSRSPQRPGWSRSRNTQRRGRSR----------SARRGRSHSRSPATRGRSRSRTP 578
Query: 216 AYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--- 272
A RS P++ S S P + S TP++ S +P R S
Sbjct: 579 ARRGRSRS--------RTPARRRSRSRTP--TRRRSRSRTPARRGRSRSRTPARRRSRTR 628
Query: 273 GSVGNGSSRYSPSQNS--PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAK 330
V S SP++ S P+RR +++ P R SR + + A+
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR 688
Query: 331 TGKFL----KRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKE 386
G+ +R + R ++R + GS R Q S E
Sbjct: 689 RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPE 748
Query: 387 SGKQKFNDSEGDDTEETEDYRQFRKSVL--------ADQGKSFATASHRNTEEEGLKYKS 438
K + + + R S+ + KS + K KS
Sbjct: 749 MKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS 808
Query: 439 KVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQV 498
+ + +R S ++ K + S++ K + R Q+ EQ
Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTPSR----QSHSSSSPHPKVKSGTPPRQGSITSPQANEQS 864
Query: 499 KSEKLKDLFDYSP--------PLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMA 550
+ + + F+ SP P + + +P R S S +P+VK ++
Sbjct: 865 VTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIIS 924
Query: 551 P 551
P
Sbjct: 925 P 925
Score = 51.2 bits (121), Expect = 4e-06
Identities = 91/380 (23%), Positives = 140/380 (36%), Gaps = 33/380 (8%)
Query: 3 RSNSRSHSS-RSKSRSQSSSRSRSRSHSRKKRYRSR-SRTYSRSRSRDRMYSRDYRRDYR 60
RS S S S R S SSS S H K R R SR+ +++ R R RR R
Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPR--RRSSR 1692
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR-SVS 119
++ + R R R R P R S S +SRS +RR S S
Sbjct: 1693 SSPELTRKARLSRRSRS---ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSAS 1749
Query: 120 SQRSRSRSRRSYRSSRSPRS-SSSRSSSPYSKSPVSKRR---GSQEKQTKKAEGELQEES 175
S R+++ SRR S PR SRS S K+ ++RR GS + +++ +
Sbjct: 1750 SPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSR 1809
Query: 176 PLKSK---SQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIAT 232
+ + S + +SS + + + S SP A+
Sbjct: 1810 VTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRAS 1869
Query: 233 PPSQSSSCSDAPMLSTVHSAKNTP------SQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 286
P + S S P++S S T S+ S+ RS + V S R S S+
Sbjct: 1870 PATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPV---SRRRSRSR 1926
Query: 287 NSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVF 346
P + RRS ++T P R RS P + ++T +R + +
Sbjct: 1927 TPP---VTRRRSRSRT------PTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPI 1977
Query: 347 LLDRGNTRDKEASKEKGSEK 366
R +R ++ + +
Sbjct: 1978 TRRRSRSRTSPVTRRRSRSR 1997
Score = 50.8 bits (120), Expect = 5e-06
Identities = 57/210 (27%), Positives = 76/210 (36%), Gaps = 18/210 (8%)
Query: 109 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA- 167
RS S S SS S S S S SS S S S SS P KR S K+A
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
Query: 168 -EGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHS 226
EG E +P K K + + SS S + SS++ S+ S S S
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 227 P------------SPIATPPSQSSSCSDAPMLSTVHSAKNTP----SQHSHSIQHSPERS 270
P SP PP + S S + ++ +++ + S Q SP
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710
Query: 271 GSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
S S GS R + H R +P+
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740
Score = 47.4 bits (111), Expect = 6e-05
Identities = 136/679 (20%), Positives = 223/679 (32%), Gaps = 75/679 (11%)
Query: 114 KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQE 173
+R +VS +S+S+ S + P +SS +S + + + E +
Sbjct: 1276 ERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRN 1335
Query: 174 ESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSP-HSPSPIAT 232
PL + E F SSE ++ N + P L + S RS HS S ++
Sbjct: 1336 SGPLGT----EMNTGF---SSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSP 1388
Query: 233 PPSQSSSCSDAPMLST--VHSAKNTPSQHSHSIQHSPE-----------RSGSGSVGNGS 279
+ + S +S+ + + TPS+ S SPE RS SGS S
Sbjct: 1389 DAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGS----S 1444
Query: 280 SRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFT 339
+P H S SP ++ PR SRGRS + +++ K L +
Sbjct: 1445 PGLRDGSGTPSRHSLSGSSPGM----KDIPRTPSRGRS-------ECDSSPEPKALPQTP 1493
Query: 340 DEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDD 399
SR N + +E+ + + + + L S S ++
Sbjct: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP 1553
Query: 400 TEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKH 459
E +E S + K+ R+ + SK L R G E DK
Sbjct: 1554 QERSES-----DSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP 1608
Query: 460 KETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDA 519
+ R + D E + R + + ++S K P + +
Sbjct: 1609 R----AAPRAQSGSDSSPEPKAPAPR-ALPRRSRSGSSSKGRG---------PSPEGSSS 1654
Query: 520 REKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKK 579
E S + + S P+ K + P + P K RL + S
Sbjct: 1655 TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714
Query: 580 EQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQ----- 634
E R+ H + P S S + T S R S
Sbjct: 1715 ETRSRTPPRHRRSPSVSSPEPAE-----KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRG 1769
Query: 635 -KATEEHSTRQKSPEIHRR--IDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADL 691
+ + S R+K+ RR S ST R+ R RV + R +
Sbjct: 1770 LQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ- 1828
Query: 692 RHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHS--LS 749
+ R + RG S+ SR + +P +K +S + H+R + + +S
Sbjct: 1829 ----ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884
Query: 750 SSSSASPSSPSSREEKESK 768
S S +SP SR S+
Sbjct: 1885 RRRSRSRTSPVSRRRSRSR 1903
Score = 47.4 bits (111), Expect = 6e-05
Identities = 60/231 (25%), Positives = 92/231 (39%), Gaps = 23/231 (9%)
Query: 93 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 152
P + + SPR S R+ R+RSR + R +S R+ SP
Sbjct: 2373 PALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP----- 2427
Query: 153 VSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPK----DTFEHDSSESIDE--FNKSSAT 206
S R G Q+ + Q SP+ S ++ + T S+S+ ++++
Sbjct: 2428 -SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486
Query: 207 CGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS 266
GD LS +P PH S + PP+ S+ L+ + AK S S S S
Sbjct: 2487 AGDHNGMLSV--PAPGVPH--SDVGEPPA-STGAQQPSALAALQPAKERRSSSSSSSSSS 2541
Query: 267 PERSGSGSVGNGSSRYSPSQNSPIHHIP------SRRSPAKTIAPQNAPRD 311
S S S + SS S S +S +P +R P+ T AP+ A R+
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592
Score = 46.6 bits (109), Expect = 1e-04
Identities = 84/355 (23%), Positives = 122/355 (34%), Gaps = 60/355 (16%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY---RSRSRTYSRSRSRDRMYSRDYRRDY 59
RS+ S S S + + S ++S S R+ SR S S S M R
Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436
Query: 60 RNNRAMRRPYGYRGRGRGYYQGGG--GRYHRGGYRPVWNRRHSRSPRRGRS--------- 108
R +R+ G G G G R+ G P + R+P RGRS
Sbjct: 1437 RRSRS--------GSSPGLRDGSGTPSRHSLSGSSPGM-KDIPRTPSRGRSECDSSPEPK 1487
Query: 109 --------RSRSP-----KRRSVSSQRSRSRSRRSYRS---SRSPRSSSSRSSSPYS--- 149
RSRSP + ++ QR RS S S +R+P SRS S
Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547
Query: 150 KSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGD 209
K S + S+ + ++ + + +S+S P E DS + S + +
Sbjct: 1548 KPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP----EVDSKSRLSPRRSRSGSSPE 1603
Query: 210 I------WPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSI 263
+ P + S P +P+P A P S S + + S S
Sbjct: 1604 VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSS--------KGRGPSPEGSSST 1655
Query: 264 QHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSS 318
+ SPE SR SP + P RRS + R R RS+
Sbjct: 1656 ESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSA 1710
Score = 46.6 bits (109), Expect = 1e-04
Identities = 68/255 (26%), Positives = 87/255 (34%), Gaps = 40/255 (15%)
Query: 13 SKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRAMRRPYGYR 72
+K R SSS S S S S S S + S S S D S + A++R
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD---SEGSSLPVQPEVALKRVPSPT 2583
Query: 73 GRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYR 132
+ + G R +P + + RS S S SS S S S S
Sbjct: 2584 PAPKEAVREG--------------RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629
Query: 133 SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHD 192
SS S SSSS SSS S SP + G Q K A + +S+S +P D+
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKPGPQ-ALPKPASPKKPPPGERRSRSPRKPIDSLRDS 2688
Query: 193 SSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSA 252
S S SP PSP +P Q SS S+
Sbjct: 2689 RSLS----------------------YSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGD 2726
Query: 253 KNTPSQHSHSIQHSP 267
+PS SP
Sbjct: 2727 SRSPSHKRRRETPSP 2741
Score = 46.2 bits (108), Expect = 1e-04
Identities = 60/247 (24%), Positives = 97/247 (39%), Gaps = 36/247 (14%)
Query: 105 RGRSRSRSPKRRSVSSQRSRSRSRRSYRSS-RSPRSSSSRSSSPYSKSPVSKRRGSQEKQ 163
R S SRSP + ++ + R RRS SS R R SS+ S+S KR+
Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRK--HRSP 232
Query: 164 TKKAEGELQEESPLKSKS-QEEPKDTFEH-----DSSESIDEFNKSSATCG-----DIWP 212
T K++ + +++ +S+S PK H DS+ S D S +
Sbjct: 233 TPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALA 292
Query: 213 GLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSA-------KNTPSQHSHSIQH 265
G S S R +P + P + S+ +P +T + K+ + +
Sbjct: 293 GRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSP 352
Query: 266 SPERSGSG----------SVGNGSS----RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRD 311
SPERS +G + +G S +P P++ PS SP + +P +P
Sbjct: 353 SPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP-PSEASPTRDRSPPKSPEK 411
Query: 312 ESRGRSS 318
+ SS
Sbjct: 412 LPQSSSS 418
Score = 46.2 bits (108), Expect = 1e-04
Identities = 62/238 (26%), Positives = 89/238 (37%), Gaps = 46/238 (19%)
Query: 132 RSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEH 191
RSS S SSSS SSS S S S GS ++ + +Q E LK P
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP---- 2586
Query: 192 DSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 251
E++ E P P+P SSS S
Sbjct: 2587 --KEAVREGR----------------------PPEPTPAKRKRRSSSSSSS--------- 2613
Query: 252 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRD 311
++ S S S S S S S + SS S S +SP P ++ K +P+ P
Sbjct: 2614 --SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671
Query: 312 ESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKE-ASKEKGSEKGR 368
E R RS P ++ + + L E R + + RD++ +S E+GS +G+
Sbjct: 2672 ERRSRSPRKP----IDSLRDSRSLSYSPVERRRP--SPQPSPRDQQSSSSERGSRRGQ 2723
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/214 (26%), Positives = 81/214 (37%), Gaps = 16/214 (7%)
Query: 113 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE-- 170
P + + Q S + + + RS SSSS SSS S S S S + +EG
Sbjct: 2509 PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568
Query: 171 -LQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSP 229
+Q E LK P E++ E T S+ S S S S
Sbjct: 2569 PVQPEVALKRVPSPTPA------PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622
Query: 230 IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSP 289
++ S SSS S + S+ S+ ++PS Q P+ + G R S S P
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR-SRSPRKP 2681
Query: 290 IHHIPSRRS------PAKTIAPQNAPRDESRGRS 317
I + RS + +PQ +PRD+ S
Sbjct: 2682 IDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715
Score = 43.1 bits (100), Expect = 0.001
Identities = 49/153 (32%), Positives = 61/153 (39%), Gaps = 22/153 (14%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDY---- 59
S+S S SS S S S SSS S S S S S S + S S S + + +
Sbjct: 2608 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK 2667
Query: 60 -----RNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 114
R +R+ R+P R Y PV RR S P +S S +
Sbjct: 2668 PPPGERRSRSPRKPIDSLRDSRSL-----------SYSPVERRRPSPQPSPRDQQSSSSE 2716
Query: 115 RRSVSSQR--SRSRSRRSYRSSRSPRSSSSRSS 145
R S QR SRS S + R + SPR RSS
Sbjct: 2717 RGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749
Score = 40.0 bits (92), Expect = 0.009
Identities = 115/579 (19%), Positives = 202/579 (34%), Gaps = 70/579 (12%)
Query: 294 PSRRSPAKTIAPQNAPRDESR--------GRSSFYPDGGDQETAKTGKFLKRFTDEESRV 345
P +R PA T Q A +E + G S Y DG + + + K+ E +
Sbjct: 112 PGQR-PAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170
Query: 346 FLLDRGNTRD-----KEASKEKGSEKGRAEGEW-------EDQEALDYFSDKESGKQKFN 393
+ L R ++ K+ K+K ++GR + + + S+ ES K+K
Sbjct: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHR 230
Query: 394 DSEGDDTEETEDYRQFR--------------KSVLADQGKSFATASHRNTEEEGLKYKSK 439
+++D ++ R +S AD S T+ R+ + +
Sbjct: 231 SPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTA 290
Query: 440 VSLKGNRESDGFREEKNDKHKETGYV-VERPSTTKDKHKE-----EDKNSERITVKKETQ 493
++ + + G R E + E G +RPS+ + K+ EDK+ ++
Sbjct: 291 LAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRP 350
Query: 494 SPEQVKSEKLKDLFDYSPPL---HKNLDAREKSTFREESPLRIKMIAS---DSHRPEVKL 547
SP +S + +P L H +T + P+ AS D P+
Sbjct: 351 SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPE 410
Query: 548 KMAPVPLDDSNRPASL-TKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQH 606
K+ +S+ P+ TK AS+ S K S I SK+ S +
Sbjct: 411 KLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS-HREISSSPTSKNRSHGRAKR 469
Query: 607 IVSLVHHVKEQYFKSAAMTLSERFTSYQKA-TEEHSTRQKSPEIHRRIDISPSTLRKDTR 665
S H + +S + ++R S + T+ +R +SP+ R + +
Sbjct: 470 DKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQ 529
Query: 666 LAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTP 725
G R + G + R + R + RS RG S + R + +TP
Sbjct: 530 RRGRSR---SPQRPGWSRSR--------NTQRRGRSRSARRGRSHSRSPATRGRSRSRTP 578
Query: 726 KDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYS 785
+S + R + + S S +P+ R S+ +T ++ S
Sbjct: 579 ARRGRSRSRTPARRRSRSRTPTRRRSRS---RTPARRGRSRSRTPARRRSRTRSPVRRRS 635
Query: 786 GFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGR 824
+R G A+RGR R RGR
Sbjct: 636 RSRSPARRSGRSRSRTP------ARRGRSRSRTPARRGR 668
Score = 40.0 bits (92), Expect = 0.009
Identities = 85/383 (22%), Positives = 133/383 (34%), Gaps = 49/383 (12%)
Query: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRAM 65
S S RS+S S S++++R+ R+ RSRS + S+ R+ R R+
Sbjct: 1550 SASPQERSESDSSPDSKAKTRTPLRQ---RSRSGSSPEVDSKSRLSPR------RSRSGS 1600
Query: 66 RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR---SPKRRSVSSQR 122
+ R Q G + +PR RSR S K R S +
Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSSPEP---------KAPAPRALPRRSRSGSSSKGRGPSPEG 1651
Query: 123 SRS---------RSRRSYRSSRSPRSSSSRSSSPYSK-----SPVSKRRGSQEKQTKKAE 168
S S +SR + R SRS ++S +P + SP R+ ++++ A
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711
Query: 169 GELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPS 228
+ S + + P + + +S + SA+ P RSP SP
Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASS----PRTKTTSRRGRSP-SPK 1766
Query: 229 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 288
P S+S S + + + S Q S RS G S Y S
Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGY--HSRS 1824
Query: 289 PIHHIPSRRSPAKTIAPQNAP---RDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRV 345
P SR S + P R SR R+S P + A + SR
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRR----SRSRT 1880
Query: 346 FLLDRGNTRDKEASKEKGSEKGR 368
L+ R +R + + + + R
Sbjct: 1881 PLISRRRSRSRTSPVSRRRSRSR 1903
Score = 39.7 bits (91), Expect = 0.012
Identities = 46/175 (26%), Positives = 67/175 (38%), Gaps = 31/175 (17%)
Query: 107 RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPY----SKSPVSKRRGSQEK 162
RS + SP+ R S+ +S+ S SP+ SRSSSP S+SP+ + RG
Sbjct: 1068 RSDTSSPEVRQSHSESPSLQSK----SQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA 1123
Query: 163 QTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGD---IWPGLSAYDX 219
G E+S +S S P DS+ + + +A + + P A
Sbjct: 1124 SPMLKSGMSPEQSRFQSDSSSYP----TVDSNSLLGQSRLETAESKEKMALPPQEDATAS 1179
Query: 220 SPRSPHSPSP----------------IATPPSQSSSCSDAPMLSTVHSAKNTPSQ 258
PR SP + TPP + S +P +SA T SQ
Sbjct: 1180 PPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQ 1234
Score = 38.1 bits (87), Expect = 0.036
Identities = 52/263 (19%), Positives = 89/263 (33%), Gaps = 21/263 (7%)
Query: 83 GGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSS 142
GG+ G RP H + + R +S S R +R + +
Sbjct: 106 GGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAP 165
Query: 143 RSSSPY--------SKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSS 194
PY S+SP K++ +K+ KK G E S + + ++ K S
Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQK---KKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222
Query: 195 ESIDEFNKSSATCGDIWPGLSAYDXSPRSPHS--PSPIATPPSQSSSCSDAPMLSTVHSA 252
ES ++S + D + S P+P + +S+S A T S
Sbjct: 223 ESKKRKHRSPTPKSK----RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSR 278
Query: 253 KNTPSQHSHSIQ---HSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP 309
+ + +H+ SP SG G G + +S + S + K +
Sbjct: 279 SRSAAAKTHTTALAGRSPS-PASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337
Query: 310 RDESRGRSSFYPDGGDQETAKTG 332
+D+ + S E + TG
Sbjct: 338 KDKDKKEKSATRPSPSPERSSTG 360
Score = 33.9 bits (76), Expect = 0.67
Identities = 36/164 (21%), Positives = 66/164 (40%), Gaps = 15/164 (9%)
Query: 620 KSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQK 679
+S + T + R S + +R +SP + RR S R R +G R + ++
Sbjct: 603 RSRSRTPARRGRSRSRTPARRRSRTRSP-VRRR-----SRSRSPARRSGRSRS-RTPARR 655
Query: 680 GDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSK 739
G + R + R R + ++ G S+ +R R + +TP+ + + S
Sbjct: 656 GRSRSRTPARRGRS----RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRS----RSRSL 707
Query: 740 HKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE 783
+R + HS + S S R+ K +R + EMK+
Sbjct: 708 VRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK 751
Score = 32.3 bits (72), Expect = 2.0
Identities = 34/144 (23%), Positives = 53/144 (36%), Gaps = 27/144 (18%)
Query: 704 KERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSS----------- 752
K R +GSR S + + +TP + +S + ++ R S S+SS
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR 1723
Query: 753 ---SASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWA 809
S S SSP E+ S + R + G + +PRG
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRG-------------L 1770
Query: 810 KRGRGRGTFQRGRGRFNFKKSGSS 833
+R R R ++ R +SGSS
Sbjct: 1771 QRSRSRSRREKTRTTRRRDRSGSS 1794
Score = 30.8 bits (68), Expect = 5.7
Identities = 20/52 (38%), Positives = 21/52 (40%)
Query: 716 RGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKES 767
R R E TP K S S S SSSSS+S SS SS S
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
>gi|115511057 hypothetical protein LOC256643 [Homo sapiens]
Length = 682
Score = 101 bits (251), Expect = 3e-21
Identities = 112/467 (23%), Positives = 196/467 (41%), Gaps = 55/467 (11%)
Query: 324 GDQETAKTGKFLKRFTDEESRVFLLDRGNT--RDKEASKEKGSEKGRAEGEWEDQEALDY 381
G ++ F KR+ ++ G+T R K+ + + E R +W+ + +L
Sbjct: 191 GSEDFETRSSFQKRYPEDRD---FRKYGHTSKRPKDVERYESREPAR-NPKWKPEHSLPP 246
Query: 382 FSDKES----GKQKFNDSEGDDTEETE------DYRQFRKSVLADQGKSFATA-SHRNTE 430
+ + G Q + +E + E + DYR R +L D + F+ + + +
Sbjct: 247 YQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLL-DGDQDFSDGRTQKYCK 305
Query: 431 EEGLKYKSKVSLKG--NRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITV 488
EE KY + KG NRE D F + +ET + K+ K K+S T
Sbjct: 306 EEDRKYSFQ---KGPLNRELDCFNTGRG---RET-----QDGQVKEPFKPSKKDSIACTY 354
Query: 489 KKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLK 548
+ + ++K K+ K ++ + + +K + + + +K
Sbjct: 355 SNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVK 414
Query: 549 MAPVPLDDSNRPAS-LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQ--ASKSTSESFIQ 605
+ D+ R AS + +R ++ LV +K + F +F+H+ Q +K T E F Q
Sbjct: 415 VDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGE-FAQ 473
Query: 606 HIVSLVHHVKEQYFKSAAMTLSERFTSYQ---KATEEHSTRQKSPEIHRRIDISPSTLRK 662
I++++H VK YF S +TL ERF++ Q KA PEIHRRID+S + L+
Sbjct: 474 EIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQ- 532
Query: 663 DTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGD---------SKGSR 713
++ V E Q K + D DLRHDI+ RRKER + + + +
Sbjct: 533 -----SKQAVIYESEQTLIKII--DPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQ 585
Query: 714 ESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPS 760
S S+ KD +K ++ + H+ + S+ P+
Sbjct: 586 NSSFSKNYTTQRKDIITHKPFEVEGNHRNTRVRPFKSNFRGGRCQPN 632
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 97.8 bits (242), Expect = 4e-20
Identities = 100/346 (28%), Positives = 138/346 (39%), Gaps = 64/346 (18%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHS-RKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
G S+ R S RS+S S + R SRS S K R RSRSR+ ++R R R S + RD
Sbjct: 379 GSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCS 438
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPR--RGRSRSRSPKRRSV 118
+R+ PY R R R + R SRSP R RSRSRSP +
Sbjct: 439 RSRS---PYKARDRSRSRSPNKARDHSR-----------SRSPNKARDRSRSRSPSKERD 484
Query: 119 SSQRSRSRSRRSYRSSRSP---------RSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169
SQ R +R SRSP RSSS S+SP +R+ Q + K
Sbjct: 485 HSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERD 544
Query: 170 ELQEESP--------LKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSP 221
Q SP +S S+E + + S E ++SS+ D
Sbjct: 545 RSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERD--------HSRS 596
Query: 222 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSR 281
RSP+ S + P + S + +HS +P + G+ S SS+
Sbjct: 597 RSPNKQSGYSRPRASS-------------------KEKAHSRSRTPSKEGNHSQSRTSSK 637
Query: 282 YSPSQNSPIHHIPS-RRSPAKT--IAPQNAPRDESRGRSSFYPDGG 324
S S + P +RSP +T ++ P S S +P GG
Sbjct: 638 ESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGG 683
Score = 88.2 bits (217), Expect = 3e-17
Identities = 109/441 (24%), Positives = 168/441 (38%), Gaps = 53/441 (12%)
Query: 10 SSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRAMRRP- 68
SSR KS +Q+S+RSR +SHS+ + R RSR+ S+ R+ R+ S ++R++ R+ R
Sbjct: 263 SSRVKSYNQASTRSRPQSHSQSRSPR-RSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG 321
Query: 69 ----YGYRGRGRGYYQGGG---GRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 121
G + R + +G R R G W+R S+ SRS S +R S
Sbjct: 322 ILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSS 381
Query: 122 RSRSRSRRSYRSSRSPRSSSSRSSSP-------YSKSPVSKRRGSQEKQTKKAEGELQEE 174
R S RS S + + SRS SP S+SP R S+ + KA +
Sbjct: 382 SPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSR 441
Query: 175 SPLKSKSQ---EEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIA 231
SP K++ + P +H S S ++ S + SP S +
Sbjct: 442 SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRS------------RSPSKERDHSQLG 489
Query: 232 TPPSQ------SSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPS 285
+P + S + + S+K + S S +R S S R
Sbjct: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
Query: 286 QNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRV 345
S RSP+K RD R RS ++E ++ + SR
Sbjct: 550 SPSEEREHRQSRSPSK-------ERDRRRWRS----PSKERERRQSRSSSEERDHSRSRS 598
Query: 346 FLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETED 405
G +R + +SKEK + R + E + S KES + D + +
Sbjct: 599 PNKQSGYSRPRASSKEKAHSRSRTPSK-EGNHSQSRTSSKESDPSQSTVPRSPDWKRSPT 657
Query: 406 YRQFRKSVLADQGKSFATASH 426
R S L+ T+SH
Sbjct: 658 ----RTSSLSQNRTPSKTSSH 674
Score = 71.2 bits (173), Expect = 4e-12
Identities = 144/658 (21%), Positives = 240/658 (36%), Gaps = 119/658 (18%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
R++ S SS ++S S+ R+ S S + R RS++RT SR + R D R +
Sbjct: 53 RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCH 112
Query: 63 RAMRRPYGYRGRGRGYYQGGG-------------GRYHRGGYR---------PVWNRRHS 100
+ RR G RGR + G GR G R P ++ S
Sbjct: 113 Q--RR--GTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGS 168
Query: 101 RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYR---------------------------- 132
R GR R+ + +R S + R+ S++SYR
Sbjct: 169 RGKSYGRPRTSNRER---SDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGI 225
Query: 133 ----SSRSPRSSSSRSSSPYSKSPVSKRRGS--------------QEKQTKKAEGELQEE 174
S +P SSSR Y + + R S Q + + Q
Sbjct: 226 PSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSR 285
Query: 175 SPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPP 234
SP +S+S + + H S S G+ S HS S +
Sbjct: 286 SPRRSRSGSQKR---THSRVRSHSWKRNHSRARSRTRKGI----LSQMGRHSQSR-SHSK 337
Query: 235 SQSSSCSDAPMLSTVHSAKNTPSQ---HSHSIQHSPERS--GSGSVGNGSSR-YSPSQNS 288
+S + S P H+ PS+ HSHS S ER GS S S R S S N
Sbjct: 338 GKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNK 397
Query: 289 PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLL 348
H S RSP N RD SR RS + D+ +++ + + S
Sbjct: 398 QRDHSRS-RSP-------NKARDRSRSRSPY--KARDRSRSRSPNKARDCSRSRSPYKAR 447
Query: 349 DRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQ 408
DR +R +++ + +A D + K++ + G ++E D+R+
Sbjct: 448 DRSRSRSPNKARDHSRSR-------SPNKARDRSRSRSPSKERDHSQLGSPSKE-RDHRR 499
Query: 409 FRKSVLADQGKSFATAS----HRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGY 464
R Q + ++S HR + + + + S N+E D R + +E +
Sbjct: 500 SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERD--RSQSRSPSEEREH 557
Query: 465 VVER-PSTTKDKH--KEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLD--- 518
R PS +D+ + K ER + ++ + +S YS P + +
Sbjct: 558 RQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAH 617
Query: 519 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHS 576
+R ++ +E + + + + +S + + +P R +SL+++R + T HS
Sbjct: 618 SRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHS 675
Score = 46.2 bits (108), Expect = 1e-04
Identities = 130/666 (19%), Positives = 236/666 (35%), Gaps = 64/666 (9%)
Query: 139 SSSSRSSSP-YSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESI 197
SS RSS P S +P + + + + + +P +S +P + S S
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
Query: 198 DEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS 257
+ KS++T A P S A PS+ S+ + S +
Sbjct: 62 SKSTKSTST-------KRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQR 114
Query: 258 QHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 317
+ +HS +P R GS S SR S H +R A + + + SRG+S
Sbjct: 115 RGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHG--ARPGMASRVRTPTSQQKGSRGKS 172
Query: 318 SFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRA-EGEWEDQ 376
P ++E + D + R N K GS GR+ E
Sbjct: 173 YGRPRTSNRERS----------DSQPR-------NLSKKSYRPPGGSGIGRSSELAVTPS 215
Query: 377 EALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKY 436
A K+K ++ + + + Y Q ++ + KS++ + + +
Sbjct: 216 TAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQM---IIPSREKSYSPTEMSSRVKSYNQA 272
Query: 437 KSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPE 496
++ + + +S R ++ K T V S ++ + + + I + S
Sbjct: 273 STRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQS 332
Query: 497 QVKSEKLKDLFDYSPPLHKNLD-AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLD 555
+ S+ +P ++ + +R S R S R D HR P
Sbjct: 333 RSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERD-HRGSSS------PRK 385
Query: 556 DSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVK 615
+S R S + ++ + S K ++ K S+S S + + K
Sbjct: 386 ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYK 445
Query: 616 EQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAG--EERVF 673
+ R S KA + +R + R SPS R ++L +ER
Sbjct: 446 ARD--------RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDH 497
Query: 674 KEENQKGDKKLRCDSADLRHDIDHRRKE---RSKERGDSKGSRESRGSRKQEKTPKDYKE 730
+ ++ S + DHRR + ++R S+ + R R Q ++P + +E
Sbjct: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKER-DRSQSRSPSEERE 556
Query: 731 YKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGV 790
++ + SK E+D S S RE ++S+ EE + H + + +G
Sbjct: 557 HRQSRSPSK---ERDRRRWRSPS------KERERRQSRSSSEE--RDHSRSRSPNKQSGY 605
Query: 791 SRPRGT 796
SRPR +
Sbjct: 606 SRPRAS 611
Score = 33.5 bits (75), Expect = 0.88
Identities = 120/648 (18%), Positives = 210/648 (32%), Gaps = 90/648 (13%)
Query: 220 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGS 279
SP+ PS P S +D +++ S K+ S + P S + + S
Sbjct: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRS-LVPTKPATSRNSVMSPSS 61
Query: 280 SRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFT 339
S+ S +S + AP N P SR RS +T K K
Sbjct: 62 SK-------------STKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASD 108
Query: 340 DE-ESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGD 398
R RG T + S+ RA G+ + + +
Sbjct: 109 VRCHQRRGTHSRGRTPGRRGSRSSKRSPSRAS---------------TPGRIRTHGARPG 153
Query: 399 DTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDK 458
+K +GKS+ N E + ++ +S K R G ++ +
Sbjct: 154 MASRVRTPTSQQKG---SRGKSYGRPRTSNRERSDSQPRN-LSKKSYRPPGGSGIGRSSE 209
Query: 459 HKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLD 518
T PST K + I K+++ +P S K+K P
Sbjct: 210 LAVT------PSTAKCQ------TPTGIPSKEKSDNPSPSSSRKVKSYGQMIIP------ 251
Query: 519 AREKSTFREESPLRIKMI--ASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHS 576
+REKS E R+K AS RP+ + R S ++ R + HS
Sbjct: 252 SREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSR-----SPRRSRSGSQKRTHSRVRSHS 306
Query: 577 VKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKA 636
K+ +A T + + + H + K + S +
Sbjct: 307 WKRNHS-----------RARSRTRKGILSQMGR--HSQSRSHSKGKSQNQSRTPRRGRSH 353
Query: 637 TEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDID 696
+ ++ H R S+ +D R + R +Q G + D + R
Sbjct: 354 NWSRNPSKERSHSHSR----SSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNK 409
Query: 697 HRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHK---REQDHSLSSSSS 753
R + RS+ ++ SR K + YK+ +D S+ + + +DHS S S
Sbjct: 410 ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKA-RDRSRSRSPNKARDHS--RSRS 466
Query: 754 ASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGR 813
+ + SR SK+ + + + +++ S+ R R + +R R
Sbjct: 467 PNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER-QCRQSRSSSKERDHRRSR 525
Query: 814 GRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKK 861
++ ++ SP D+ Q E+ E + K+
Sbjct: 526 SPSKERQ-------RRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKE 566
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 90.1 bits (222), Expect = 8e-18
Identities = 78/213 (36%), Positives = 97/213 (45%), Gaps = 28/213 (13%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD----- 58
S SR+ SSRS SRS S SR + + RSRSR++SRSRSR R YSR R
Sbjct: 385 SASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSG 444
Query: 59 --------YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGG----------YRPVWNRRHS 100
Y + A R YG R R R G RY RGG R W+ S
Sbjct: 445 GGSRDGHRYSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPS 503
Query: 101 RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSR-SSSPYSKSPVSKRRGS 159
RS RSRS SP S S RSRSRSR S R +R ++SP + K +
Sbjct: 504 RSRSLTRSRSHSP---SPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPA 560
Query: 160 QEKQTKKAEGELQEESPLKSKSQEEPKDTFEHD 192
K+T A+ +L + LK + Q+ F+ D
Sbjct: 561 AGKETGAAKPKLTPQEKLKLRMQKALNRQFKAD 593
Score = 48.1 bits (113), Expect = 3e-05
Identities = 74/262 (28%), Positives = 98/262 (37%), Gaps = 27/262 (10%)
Query: 19 SSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRD----YRRDYRNNRAMRRPYGYRGR 74
S +R S ++ KR S S + SRSRSR R+ + + +
Sbjct: 288 SYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAA 347
Query: 75 GRGYYQG-GGGRYHRGGYRPVWN---RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 130
G G GG P N RR S S S SR+ R SS RS SRSRR
Sbjct: 348 ASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSR--SSSRSSSRSRRG 405
Query: 131 ---YRSSRSPRSSS---SRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPL------- 177
YRS R RS S SRS S + S+ RG + +G SP
Sbjct: 406 GGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGP 465
Query: 178 --KSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPS 235
+S+S+ D + + S + + P S RS HSPSP + S
Sbjct: 466 RRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRS-HSPSP-SQSRS 523
Query: 236 QSSSCSDAPMLSTVHSAKNTPS 257
+S S S +P S P+
Sbjct: 524 RSRSRSQSPSPSPAREKLTRPA 545
Score = 44.7 bits (104), Expect = 4e-04
Identities = 100/463 (21%), Positives = 166/463 (35%), Gaps = 84/463 (18%)
Query: 108 SRSRSPKRRSVSSQRSRSRSRRSYRSSR------SPRSSSSRSS---SPYSKSPVSKRRG 158
+++ ++ S +RSR R RR +R R SP S + R S PY +SP
Sbjct: 252 AKALEEEKAMYSGRRSR-RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE 310
Query: 159 SQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYD 218
S+ + G E K TF S DE ++A +
Sbjct: 311 SRSRSRSPTPGR-------------EEKITFITSFGGS-DEEAAAAAAAAAASGVTTGKP 356
Query: 219 XSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNG 278
+P P P+P ++ S S S+ SA T S S S S R G G +G
Sbjct: 357 PAPPQPGGPAPGRNASARRRSSSS----SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSG 412
Query: 279 ----------------SSRYSPSQNSPIHHIPS--------RRSPAKTIAPQNAPRDESR 314
S RYS S++ H RSPA+ PR SR
Sbjct: 413 RHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR--RGGYGPRRRSR 470
Query: 315 GRSSFYPDGGDQETAKTGKFLKRFTDEESR---VFLLDRGNTRDKEASKEKGSEKGRAEG 371
RS GD+ + G+ L+ + SR R + + S + R+
Sbjct: 471 SRS----HSGDR-YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRS 525
Query: 372 EWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEE 431
Q + ++ + + + G+ ++TE GK A + T +
Sbjct: 526 RSRSQSPSPSPAREKLTRPAASPAVGEKLKKTE----------PAAGKETGAAKPKLTPQ 575
Query: 432 EGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVK-K 490
E LK + + +L R+ K DK ++++ +++ E + +I +K +
Sbjct: 576 EKLKLRMQKALN--------RQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKER 627
Query: 491 ETQSPEQVKSEKLKDLFDYSPPLHKNLD---AREKSTFREESP 530
E + E+ + E+ SP + + +R +S R SP
Sbjct: 628 ERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSP 670
Score = 39.7 bits (91), Expect = 0.012
Identities = 49/182 (26%), Positives = 68/182 (37%), Gaps = 37/182 (20%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS-----RKKRYRSRSRTYSRSRSRDRM-------- 50
S+SRS SS S S S+S S +RSRSHS + R RSRS++ S S +R+++
Sbjct: 490 SSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549
Query: 51 ----------------------YSRDYRRDYRNNRAMRRPY--GYRGRGRGYYQGGGGRY 86
+ + R +A+ R + + Q R
Sbjct: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQ 609
Query: 87 HRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 146
R R+ R R + R R S Q R S S S R S SRS S
Sbjct: 610 EREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
Query: 147 PY 148
P+
Sbjct: 670 PH 671
Score = 32.0 bits (71), Expect = 2.6
Identities = 20/87 (22%), Positives = 47/87 (54%), Gaps = 8/87 (9%)
Query: 662 KDTRLAGEERVFKEENQKGDKK--LRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSR 719
K + A +E++ ++E+++ +++ LR + +R + R+E+ +E + + SR+SR
Sbjct: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMK-ERERREKEREEWERQYSRQSRSP- 648
Query: 720 KQEKTPKDYKEYKSYKDDSKHKREQDH 746
+P+ +EY S + S+ + H
Sbjct: 649 ----SPRYSREYSSSRRRSRSRSRSPH 671
Score = 31.2 bits (69), Expect = 4.4
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 4/70 (5%)
Query: 7 RSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRS---RTYSR-SRSRDRMYSRDYRRDYRNN 62
+ H + + + + R R++R + R R YSR SRS YSR+Y R +
Sbjct: 604 QEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRS 663
Query: 63 RAMRRPYGYR 72
R+ R YR
Sbjct: 664 RSRSRSPHYR 673
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 87.8 bits (216), Expect = 4e-17
Identities = 91/283 (32%), Positives = 122/283 (43%), Gaps = 32/283 (11%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRY-RSRSRTYSRSRSRDRMYSRDYRRDYR 60
S S + SS S S S SSR+ SRS S RKKR+ RSRS T RSR R YSR R
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR--RIKIE 583
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRSV 118
+NRA + R R + RR +RSP R RSRSRS RR+
Sbjct: 584 SNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRTN 629
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGELQEESP 176
+ RSRSR RR R S +S +K K+ S+ +K KK + E + E
Sbjct: 630 RASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689
Query: 177 LKSKSQEEPKDTFEHDSS--------ESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPS 228
+ + Q+ + F+ S ES F++S + I S D +
Sbjct: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749
Query: 229 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 271
+ S S S++P S AK S S++ S +RSG
Sbjct: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791
Score = 55.5 bits (132), Expect = 2e-07
Identities = 88/398 (22%), Positives = 160/398 (40%), Gaps = 52/398 (13%)
Query: 397 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 456
G + ++ED R R S +D T++E L+++ + + + ++ +
Sbjct: 390 GYGSGDSEDERSDRGSESSD------------TDDEELRHRIRQKQEAFWRKEKEQQLLH 437
Query: 457 DKHKETGYVVERPST---TKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPL 513
DK E E+ T TK+ ++ K +++ + ++ V +EK + + + L
Sbjct: 438 DKQMEE----EKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVL 493
Query: 514 HKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 573
+ +EK ++ R +S S + + S+ +S R +S
Sbjct: 494 EPKKEHKEKE---KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT-SSRS 549
Query: 574 VHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSY 633
+K++ RS IK A +S S S+ + I + A + + +R S
Sbjct: 550 SSPKRKKRHSRSRSPTIK---ARRSRSRSYSRRI--------KIESNRARVKIRDRRRSN 598
Query: 634 QKATEEHSTRQKSPEIHRRIDISPSTLRK----------DTRLAGEERVFKEENQ---KG 680
+ + E R +SP RR S S R+ D R ++R N KG
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKG 658
Query: 681 DKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKH 740
+ K + + ID RK++ KER + R+ KQ++ KD+K + S D K
Sbjct: 659 EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFK-FSSQDDRLKR 713
Query: 741 KREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTH 778
KRE + + S S S S ++SKK ++ K H
Sbjct: 714 KRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
Score = 52.8 bits (125), Expect = 1e-06
Identities = 137/711 (19%), Positives = 260/711 (36%), Gaps = 116/711 (16%)
Query: 221 PRSPHSPSPI-ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGS 279
P P +P P+ PPS+ S+ D+ + + ++ +Q++H+ P+ G V
Sbjct: 108 PWMPPTPGPMDIVPPSEDSNSQDSGEFAPDN--RHIFNQNNHNFGGPPDNFAVGPVNQFD 165
Query: 280 SRY------------------------SPSQNS---PIHHIPSRRSPAKTIAPQNAPRDE 312
++ +P QN P +RSP Q P+ +
Sbjct: 166 YQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQID 225
Query: 313 S---RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE---- 365
+ R ++ +G ++ + K L++ E+ R L + ++A G
Sbjct: 226 AVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQR 285
Query: 366 -KGRAEGEWEDQEALDYFSDKESGKQKFNDS-----EGDDTEETEDYRQFRKSVLADQGK 419
K ++ E ED E ++ S SGK + S E D E TE+ ++++ +L K
Sbjct: 286 SKFDSDEEEEDTENVEAAS---SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT---K 339
Query: 420 SFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTK------ 473
T + +E + Y +K D R+ K+ S T
Sbjct: 340 MLLTEILLDVTDEEIYYVAK---------DAHRKATKAPAKQLAQSSALASLTGLGGLGG 390
Query: 474 -DKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLR 532
ED+ S+R + +T E L + ++++ +R+E +
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEE----------------LRHRIRQKQEAFWRKEKEQQ 434
Query: 533 I---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE-QEFRSIFD 588
+ K + + + E K + SL + R +V+ K+ E S+ +
Sbjct: 435 LLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLE 494
Query: 589 ----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQ 644
H + + +S S S S S + T+S S + S+R
Sbjct: 495 PKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSSSSYSSSSGSSRTSSRS 549
Query: 645 KSPEIHRRIDIS--PSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRK-- 700
SP+ +R S P+ + +R R K E+ + K+R R+ I+ R+
Sbjct: 550 SSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRN 609
Query: 701 -----ERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKRE-QDHSLSSSSSA 754
ER + R S+ R +R SR + + + + + + HK + +
Sbjct: 610 RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
Query: 755 SPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDR----DDGVDYWAK 810
S S R++K+ ++ERE++ + + +E F S+ DDR + +++
Sbjct: 670 SRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQ------DDRLKRKRESERTFSR 723
Query: 811 RGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKK 861
G R R + KKS + H G E+ +++EKK
Sbjct: 724 SGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSG--RSSSESPGSSKEKK 772
Score = 45.4 bits (106), Expect = 2e-04
Identities = 46/179 (25%), Positives = 73/179 (40%), Gaps = 28/179 (15%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA 64
NS H +K + + RSRS RKK+ + R R + + + + +D++ +++R
Sbjct: 652 NSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL 711
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
R+ R + R G V RH SR S K+ + +
Sbjct: 712 KRKRESER------------TFSRSGSISVKIIRHD-------SRQDS-KKSTTKDSKKH 751
Query: 125 SRSRRSYR-SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQ 182
S S S R SS SP SS + +K P R S EK + + ++ KSKS+
Sbjct: 752 SGSDSSGRSSSESPGSSKEKK----AKKPKHSRSRSVEKSQRSGKKASRKH---KSKSR 803
Score = 43.9 bits (102), Expect = 6e-04
Identities = 87/427 (20%), Positives = 165/427 (38%), Gaps = 47/427 (11%)
Query: 359 SKEKGSEKGRAEGEWEDQEALDYFSDK-ESGKQKFNDSEGDDTEETEDYRQFRKSVLADQ 417
S+++ S++G + +D+E K E+ +K + + ++ E+ +Q + V +
Sbjct: 396 SEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEM 455
Query: 418 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDG-FREEKNDKHKETGYVVERPSTTKDKH 476
+ K ++ +SL RE+DG EK ET V+E K +H
Sbjct: 456 NEFIH------------KEQNSLSLLEAREADGDVVNEKKRTPNETTSVLE----PKKEH 499
Query: 477 KEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMI 536
KE++K + + S S S + + +++ R SP R K
Sbjct: 500 KEKEKQGRSRSGSSSSGSSSS-NSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKR- 557
Query: 537 ASDSHRPEVKLKMAPVPLD------DSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHI 590
S S P +K + + +SNR +DR ++ +S+++E+ R
Sbjct: 558 HSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNR--NSIERER--RRNRSPS 613
Query: 591 KLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIH 650
+ + S+S S + S + LS ++ +E +++
Sbjct: 614 RERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE----- 668
Query: 651 RRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSK 710
R I +KD E+ KE+ ++ +K + S D D +++R ER S+
Sbjct: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQD-----DRLKRKRESERTFSR 723
Query: 711 GSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKE 770
S + + K + KD KH SS +S SP S +EK++KK
Sbjct: 724 SGSISVKIIRHDSRQDSKKS--TTKDSKKHS-----GSDSSGRSSSESPGSSKEKKAKKP 776
Query: 771 REEEFKT 777
+ ++
Sbjct: 777 KHSRSRS 783
Score = 43.9 bits (102), Expect = 6e-04
Identities = 76/355 (21%), Positives = 129/355 (36%), Gaps = 57/355 (16%)
Query: 163 QTKKAEGELQEE---SPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDX 219
+ ++A+G++ E +P ++ S EPK EH E S++ G
Sbjct: 470 EAREADGDVVNEKKRTPNETTSVLEPKK--EHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
Query: 220 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS---QHSHSIQHSPE-------- 268
S S ++ S++SS S +P HS +P+ + S S +S
Sbjct: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
Query: 269 ----RSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGG 324
R S N R SP RS ++ A R SR R
Sbjct: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI----D 643
Query: 325 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYF 382
DQ +G K +G +++E KE+ +K R + + E + D
Sbjct: 644 DQRGNLSGNSHKH------------KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR 691
Query: 383 SDKESGKQK-FNDSEGDDT--EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSK 439
+K+ ++K F S DD + E R F +S G ++ ++ K +K
Sbjct: 692 KEKQKREEKDFKFSSQDDRLKRKRESERTFSRS-----GSISVKIIRHDSRQDSKKSTTK 746
Query: 440 VSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 494
S K + R E P ++K+K ++ K+S +V+K +S
Sbjct: 747 DSKKHSGSDSSGRSSS-----------ESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
Score = 42.0 bits (97), Expect = 0.002
Identities = 97/464 (20%), Positives = 160/464 (34%), Gaps = 48/464 (10%)
Query: 430 EEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVK 489
E E K K ++ R +E+K + E G P +K EE++++E +
Sbjct: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
Query: 490 ---KETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE----ESPLRIKMIASDSHR 542
K T+SP V E+ D + K E + I +A D+HR
Sbjct: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
Query: 543 PEVKLKMAPV-PLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 601
K AP L S+ ASLT L + E+ R S T +
Sbjct: 364 KATK---APAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG--------SESSDTDD 412
Query: 602 SFIQHIVSLVHHVKEQYF---KSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658
++H + K++ F + L ++ +K E T++ + IH+ S
Sbjct: 413 EELRHRI----RQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKE---QNS 465
Query: 659 TLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKE---RSKERGDSKGSRES 715
+ R A + V +++ + ++ L +H+ KE RS+ S GS S
Sbjct: 466 LSLLEAREADGDVVNEKKRTPNE-----TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSS 520
Query: 716 RGSRKQEKTPKDYKEYKSYKDDSK-------HKREQDHSLSSSSSASPSSPSSREEKESK 768
+ Y S S+ KR++ HS S S + SR
Sbjct: 521 NSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRI 580
Query: 769 KEREEEFKTHHEMKEYSGFAGVSRPRGTFHD---DRDDGVDYWAKRGRGRGTFQRGRGRF 825
K + + S + R R +R R R + R R R
Sbjct: 581 KIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRR 640
Query: 826 NFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKKDRCKEEKE 869
+ N K++G+ E E + + KDR K++KE
Sbjct: 641 KIDDQRGNLSGNSHKHKGEA-KEQERKKERSRSIDKDRKKKDKE 683
Score = 37.7 bits (86), Expect = 0.047
Identities = 23/66 (34%), Positives = 32/66 (48%)
Query: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 156
+ H ++GRSRS S S SS S + + SS SS S +S S SP K+
Sbjct: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKK 556
Query: 157 RGSQEK 162
R S+ +
Sbjct: 557 RHSRSR 562
Score = 34.3 bits (77), Expect = 0.51
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 101 RSPRRGRSRSRSPKRRSVSSQRSRSR-----SRRSYRSSRSPRSSSSRSSSPYSKSPVSK 155
R+P S K ++ RSR S S +SR+ +SS+ SSS YS S S
Sbjct: 484 RTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSS 543
Query: 156 RRGSQEKQTKKAEGELQEESP 176
R S+ K+ + + SP
Sbjct: 544 RTSSRSSSPKRKKRHSRSRSP 564
Score = 32.3 bits (72), Expect = 2.0
Identities = 16/48 (33%), Positives = 27/48 (56%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDR 49
GRS+S S S + +++ SRSRS + +R ++ +S+SR R
Sbjct: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 87.8 bits (216), Expect = 4e-17
Identities = 91/283 (32%), Positives = 122/283 (43%), Gaps = 32/283 (11%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRY-RSRSRTYSRSRSRDRMYSRDYRRDYR 60
S S + SS S S S SSR+ SRS S RKKR+ RSRS T RSR R YSR R
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR--RIKIE 583
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRSV 118
+NRA + R R + RR +RSP R RSRSRS RR+
Sbjct: 584 SNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRTN 629
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGELQEESP 176
+ RSRSR RR R S +S +K K+ S+ +K KK + E + E
Sbjct: 630 RASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689
Query: 177 LKSKSQEEPKDTFEHDSS--------ESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPS 228
+ + Q+ + F+ S ES F++S + I S D +
Sbjct: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749
Query: 229 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 271
+ S S S++P S AK S S++ S +RSG
Sbjct: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791
Score = 55.5 bits (132), Expect = 2e-07
Identities = 88/398 (22%), Positives = 160/398 (40%), Gaps = 52/398 (13%)
Query: 397 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 456
G + ++ED R R S +D T++E L+++ + + + ++ +
Sbjct: 390 GYGSGDSEDERSDRGSESSD------------TDDEELRHRIRQKQEAFWRKEKEQQLLH 437
Query: 457 DKHKETGYVVERPST---TKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPL 513
DK E E+ T TK+ ++ K +++ + ++ V +EK + + + L
Sbjct: 438 DKQMEE----EKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVL 493
Query: 514 HKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 573
+ +EK ++ R +S S + + S+ +S R +S
Sbjct: 494 EPKKEHKEKE---KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT-SSRS 549
Query: 574 VHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSY 633
+K++ RS IK A +S S S+ + I + A + + +R S
Sbjct: 550 SSPKRKKRHSRSRSPTIK---ARRSRSRSYSRRI--------KIESNRARVKIRDRRRSN 598
Query: 634 QKATEEHSTRQKSPEIHRRIDISPSTLRK----------DTRLAGEERVFKEENQ---KG 680
+ + E R +SP RR S S R+ D R ++R N KG
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKG 658
Query: 681 DKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKH 740
+ K + + ID RK++ KER + R+ KQ++ KD+K + S D K
Sbjct: 659 EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFK-FSSQDDRLKR 713
Query: 741 KREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTH 778
KRE + + S S S S ++SKK ++ K H
Sbjct: 714 KRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
Score = 52.8 bits (125), Expect = 1e-06
Identities = 137/711 (19%), Positives = 260/711 (36%), Gaps = 116/711 (16%)
Query: 221 PRSPHSPSPI-ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGS 279
P P +P P+ PPS+ S+ D+ + + ++ +Q++H+ P+ G V
Sbjct: 108 PWMPPTPGPMDIVPPSEDSNSQDSGEFAPDN--RHIFNQNNHNFGGPPDNFAVGPVNQFD 165
Query: 280 SRY------------------------SPSQNS---PIHHIPSRRSPAKTIAPQNAPRDE 312
++ +P QN P +RSP Q P+ +
Sbjct: 166 YQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQID 225
Query: 313 S---RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE---- 365
+ R ++ +G ++ + K L++ E+ R L + ++A G
Sbjct: 226 AVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQR 285
Query: 366 -KGRAEGEWEDQEALDYFSDKESGKQKFNDS-----EGDDTEETEDYRQFRKSVLADQGK 419
K ++ E ED E ++ S SGK + S E D E TE+ ++++ +L K
Sbjct: 286 SKFDSDEEEEDTENVEAAS---SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT---K 339
Query: 420 SFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTK------ 473
T + +E + Y +K D R+ K+ S T
Sbjct: 340 MLLTEILLDVTDEEIYYVAK---------DAHRKATKAPAKQLAQSSALASLTGLGGLGG 390
Query: 474 -DKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLR 532
ED+ S+R + +T E L + ++++ +R+E +
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEE----------------LRHRIRQKQEAFWRKEKEQQ 434
Query: 533 I---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE-QEFRSIFD 588
+ K + + + E K + SL + R +V+ K+ E S+ +
Sbjct: 435 LLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLE 494
Query: 589 ----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQ 644
H + + +S S S S S + T+S S + S+R
Sbjct: 495 PKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSSSSYSSSSGSSRTSSRS 549
Query: 645 KSPEIHRRIDIS--PSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRK-- 700
SP+ +R S P+ + +R R K E+ + K+R R+ I+ R+
Sbjct: 550 SSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRN 609
Query: 701 -----ERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKRE-QDHSLSSSSSA 754
ER + R S+ R +R SR + + + + + + HK + +
Sbjct: 610 RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
Query: 755 SPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDR----DDGVDYWAK 810
S S R++K+ ++ERE++ + + +E F S+ DDR + +++
Sbjct: 670 SRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQ------DDRLKRKRESERTFSR 723
Query: 811 RGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKK 861
G R R + KKS + H G E+ +++EKK
Sbjct: 724 SGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSG--RSSSESPGSSKEKK 772
Score = 45.4 bits (106), Expect = 2e-04
Identities = 46/179 (25%), Positives = 73/179 (40%), Gaps = 28/179 (15%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA 64
NS H +K + + RSRS RKK+ + R R + + + + +D++ +++R
Sbjct: 652 NSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL 711
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
R+ R + R G V RH SR S K+ + +
Sbjct: 712 KRKRESER------------TFSRSGSISVKIIRHD-------SRQDS-KKSTTKDSKKH 751
Query: 125 SRSRRSYR-SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQ 182
S S S R SS SP SS + +K P R S EK + + ++ KSKS+
Sbjct: 752 SGSDSSGRSSSESPGSSKEKK----AKKPKHSRSRSVEKSQRSGKKASRKH---KSKSR 803
Score = 43.9 bits (102), Expect = 6e-04
Identities = 87/427 (20%), Positives = 165/427 (38%), Gaps = 47/427 (11%)
Query: 359 SKEKGSEKGRAEGEWEDQEALDYFSDK-ESGKQKFNDSEGDDTEETEDYRQFRKSVLADQ 417
S+++ S++G + +D+E K E+ +K + + ++ E+ +Q + V +
Sbjct: 396 SEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEM 455
Query: 418 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDG-FREEKNDKHKETGYVVERPSTTKDKH 476
+ K ++ +SL RE+DG EK ET V+E K +H
Sbjct: 456 NEFIH------------KEQNSLSLLEAREADGDVVNEKKRTPNETTSVLE----PKKEH 499
Query: 477 KEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMI 536
KE++K + + S S S + + +++ R SP R K
Sbjct: 500 KEKEKQGRSRSGSSSSGSSSS-NSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKR- 557
Query: 537 ASDSHRPEVKLKMAPVPLD------DSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHI 590
S S P +K + + +SNR +DR ++ +S+++E+ R
Sbjct: 558 HSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNR--NSIERER--RRNRSPS 613
Query: 591 KLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIH 650
+ + S+S S + S + LS ++ +E +++
Sbjct: 614 RERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE----- 668
Query: 651 RRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSK 710
R I +KD E+ KE+ ++ +K + S D D +++R ER S+
Sbjct: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQD-----DRLKRKRESERTFSR 723
Query: 711 GSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKE 770
S + + K + KD KH SS +S SP S +EK++KK
Sbjct: 724 SGSISVKIIRHDSRQDSKKS--TTKDSKKHS-----GSDSSGRSSSESPGSSKEKKAKKP 776
Query: 771 REEEFKT 777
+ ++
Sbjct: 777 KHSRSRS 783
Score = 43.9 bits (102), Expect = 6e-04
Identities = 76/355 (21%), Positives = 129/355 (36%), Gaps = 57/355 (16%)
Query: 163 QTKKAEGELQEE---SPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDX 219
+ ++A+G++ E +P ++ S EPK EH E S++ G
Sbjct: 470 EAREADGDVVNEKKRTPNETTSVLEPKK--EHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
Query: 220 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS---QHSHSIQHSPE-------- 268
S S ++ S++SS S +P HS +P+ + S S +S
Sbjct: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
Query: 269 ----RSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGG 324
R S N R SP RS ++ A R SR R
Sbjct: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI----D 643
Query: 325 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYF 382
DQ +G K +G +++E KE+ +K R + + E + D
Sbjct: 644 DQRGNLSGNSHKH------------KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR 691
Query: 383 SDKESGKQK-FNDSEGDDT--EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSK 439
+K+ ++K F S DD + E R F +S G ++ ++ K +K
Sbjct: 692 KEKQKREEKDFKFSSQDDRLKRKRESERTFSRS-----GSISVKIIRHDSRQDSKKSTTK 746
Query: 440 VSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 494
S K + R E P ++K+K ++ K+S +V+K +S
Sbjct: 747 DSKKHSGSDSSGRSSS-----------ESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
Score = 42.0 bits (97), Expect = 0.002
Identities = 97/464 (20%), Positives = 160/464 (34%), Gaps = 48/464 (10%)
Query: 430 EEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVK 489
E E K K ++ R +E+K + E G P +K EE++++E +
Sbjct: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
Query: 490 ---KETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE----ESPLRIKMIASDSHR 542
K T+SP V E+ D + K E + I +A D+HR
Sbjct: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
Query: 543 PEVKLKMAPV-PLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 601
K AP L S+ ASLT L + E+ R S T +
Sbjct: 364 KATK---APAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG--------SESSDTDD 412
Query: 602 SFIQHIVSLVHHVKEQYF---KSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658
++H + K++ F + L ++ +K E T++ + IH+ S
Sbjct: 413 EELRHRI----RQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKE---QNS 465
Query: 659 TLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKE---RSKERGDSKGSRES 715
+ R A + V +++ + ++ L +H+ KE RS+ S GS S
Sbjct: 466 LSLLEAREADGDVVNEKKRTPNE-----TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSS 520
Query: 716 RGSRKQEKTPKDYKEYKSYKDDSK-------HKREQDHSLSSSSSASPSSPSSREEKESK 768
+ Y S S+ KR++ HS S S + SR
Sbjct: 521 NSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRI 580
Query: 769 KEREEEFKTHHEMKEYSGFAGVSRPRGTFHD---DRDDGVDYWAKRGRGRGTFQRGRGRF 825
K + + S + R R +R R R + R R R
Sbjct: 581 KIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRR 640
Query: 826 NFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKKDRCKEEKE 869
+ N K++G+ E E + + KDR K++KE
Sbjct: 641 KIDDQRGNLSGNSHKHKGEA-KEQERKKERSRSIDKDRKKKDKE 683
Score = 37.7 bits (86), Expect = 0.047
Identities = 23/66 (34%), Positives = 32/66 (48%)
Query: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 156
+ H ++GRSRS S S SS S + + SS SS S +S S SP K+
Sbjct: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKK 556
Query: 157 RGSQEK 162
R S+ +
Sbjct: 557 RHSRSR 562
Score = 34.3 bits (77), Expect = 0.51
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 101 RSPRRGRSRSRSPKRRSVSSQRSRSR-----SRRSYRSSRSPRSSSSRSSSPYSKSPVSK 155
R+P S K ++ RSR S S +SR+ +SS+ SSS YS S S
Sbjct: 484 RTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSS 543
Query: 156 RRGSQEKQTKKAEGELQEESP 176
R S+ K+ + + SP
Sbjct: 544 RTSSRSSSPKRKKRHSRSRSP 564
Score = 32.3 bits (72), Expect = 2.0
Identities = 16/48 (33%), Positives = 27/48 (56%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDR 49
GRS+S S S + +++ SRSRS + +R ++ +S+SR R
Sbjct: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 85.9 bits (211), Expect = 1e-16
Identities = 62/195 (31%), Positives = 94/195 (48%), Gaps = 6/195 (3%)
Query: 11 SRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRAMRRPYG 70
SRS+ R +S SRSR R R+ R R R + R R RDR Y ++ + R R
Sbjct: 330 SRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERS 389
Query: 71 YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 130
R RG + + + R ++R S+ ++ SRSRS +R+ S RSR+ +RS
Sbjct: 390 KEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK-HSRSRSRERKHRSRSRSRNAGKRS 448
Query: 131 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKD--- 187
SRS SS + KS R GSQ + + + +E SP K KS++ +
Sbjct: 449 --RSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKER 506
Query: 188 TFEHDSSESIDEFNK 202
+ + D S+S D+ +K
Sbjct: 507 SHKRDHSDSKDQSDK 521
Score = 58.2 bits (139), Expect = 3e-08
Identities = 55/185 (29%), Positives = 79/185 (42%), Gaps = 22/185 (11%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRD------RMYSRDY 55
GR R + K R + R RS R K RSR + D R RD
Sbjct: 363 GRRRDRDYD---KERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDS 419
Query: 56 RRDYRNNRAMRRPYGYRGRGRGYYQGGGGRY--------HRGGYRPVWNRRHSRSPRRGR 107
+++ +++R+ R +R R R G R H+ + N+R SRS +GR
Sbjct: 420 KKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR-SRSGSQGR 478
Query: 108 SRS--RSPKR-RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYS-KSPVSKRRGSQEKQ 163
+ S +S KR S S ++SR RSR RS + S S S + + S + SQEKQ
Sbjct: 479 TDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQ 538
Query: 164 TKKAE 168
K +
Sbjct: 539 HKNKD 543
Score = 55.8 bits (133), Expect = 2e-07
Identities = 60/254 (23%), Positives = 104/254 (40%), Gaps = 22/254 (8%)
Query: 292 HIPSRRS--PAKTIAPQNAPRD--------ESRGRSSFYPD-GGDQETAKTGKFLKRFTD 340
H+ RRS P ++++P+ +PR E G SSF + ++E + + K
Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREK 313
Query: 341 EESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDT 400
E R +DRG R + S+E+ + R+ D+ D +KE+ + + D + D
Sbjct: 314 ERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKE 373
Query: 401 EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHK 460
E ++ +S + +S S EE+ K K R D R+ K +K
Sbjct: 374 RGNEREKERERS----RERSKEQRSRGEVEEK----KHKEDKDDRRHRDDKRDSKKEKKH 425
Query: 461 ETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAR 520
ER ++ + + K S + +K ++ + K + K S D+
Sbjct: 426 SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGS---QGRTDSV 482
Query: 521 EKSTFREESPLRIK 534
EKS RE SP + K
Sbjct: 483 EKSKKREHSPSKEK 496
Score = 52.8 bits (125), Expect = 1e-06
Identities = 55/264 (20%), Positives = 107/264 (40%), Gaps = 37/264 (14%)
Query: 613 HVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERV 672
HV+ + +S +LS R + + + H HR S S R+ R +R+
Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRSRSH---------HREGHGSSSFDRELEREKERQRL 304
Query: 673 FKEENQKGDKKLRCDSADLRHDIDHRRKERSKERG-------DSKGSRESRGSRKQEKTP 725
+E ++ ++ R S D + RR+ RS+ER D KG R R ++++
Sbjct: 305 EREAKEREKERRRSRSIDRGLE---RRRSRSRERHRSRSRSRDRKGDRRDRDREREKENE 361
Query: 726 KDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYS 785
+ + + Y + ++RE++ S S S EEK+ K+++++ + H + K
Sbjct: 362 RGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDD--RRHRDDKR-- 417
Query: 786 GFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDG 845
D + R R R R R R K+S S K K++ +
Sbjct: 418 --------------DSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNES 463
Query: 846 IVEDEEETMENNEEKKDRCKEEKE 869
+ + + ++ + D ++ K+
Sbjct: 464 KEKSNKRSRSGSQGRTDSVEKSKK 487
Score = 47.8 bits (112), Expect = 4e-05
Identities = 27/123 (21%), Positives = 53/123 (43%), Gaps = 5/123 (4%)
Query: 662 KDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQ 721
K+ R GE K + K D++ R D D + + H R + + S+ + G R +
Sbjct: 390 KEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSR 449
Query: 722 EKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPS-----SPSSREEKESKKEREEEFK 776
++ + ++K+ + +KR + S + S S SPS + ++ + +E K
Sbjct: 450 SRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHK 509
Query: 777 THH 779
H
Sbjct: 510 RDH 512
Score = 46.2 bits (108), Expect = 1e-04
Identities = 71/313 (22%), Positives = 111/313 (35%), Gaps = 24/313 (7%)
Query: 18 QSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRAMRRPYGYRGRGRG 77
Q + + ++ RK + + R +R SR RR R+ RR R R
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRR-----SRSRS 280
Query: 78 YYQGGGGR--YHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS-S 134
+++ G G + R R +R R + R + +R RSRSR +RS S
Sbjct: 281 HHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRS 340
Query: 135 RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSS 194
RS R + ++R +++ K G +E K +E ++ + S
Sbjct: 341 RSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNERE------KERERSRERSKEQRS 394
Query: 195 ESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCS-DAPMLSTVHSAK 253
E K D D HS S +S S S +A S S +
Sbjct: 395 RGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKE 454
Query: 254 NTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDES 313
+ + S + S +RS SGS G S ++ H PS+ K R +
Sbjct: 455 KSSKHKNESKEKSNKRSRSGSQGRTD---SVEKSKKREHSPSKEKSRK------RSRSKE 505
Query: 314 RGRSSFYPDGGDQ 326
R + D DQ
Sbjct: 506 RSHKRDHSDSKDQ 518
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/267 (20%), Positives = 110/267 (41%), Gaps = 21/267 (7%)
Query: 249 VHSAKNTPSQHSHSIQHSPERSGSGS---VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 305
V ++ + S S + SP RS S S G+GSS + R +
Sbjct: 255 VERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKE 314
Query: 306 QNAPRDESRG----RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKE 361
+ R RG RS + ++ K +R D E R +RG RD++ KE
Sbjct: 315 RRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRE-REKENERGRRRDRDYDKE 373
Query: 362 KGSEKG----RAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQF-------R 410
+G+E+ R+ ++Q + +K+ + K + DD +++ ++ R
Sbjct: 374 RGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRER 433
Query: 411 KSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPS 470
K + ++ S ++E+ K+K++ K N+ S + + D +++ PS
Sbjct: 434 KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPS 493
Query: 471 TTKDKHKEEDKNSERITVKKETQSPEQ 497
K+K ++ ++ ER + + S +Q
Sbjct: 494 --KEKSRKRSRSKERSHKRDHSDSKDQ 518
Score = 39.3 bits (90), Expect = 0.016
Identities = 37/182 (20%), Positives = 77/182 (42%), Gaps = 8/182 (4%)
Query: 691 LRHDIDHRRKERSKE-RGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLS 749
++ +ID + K R ++ + D K E + + + + S + + R + H
Sbjct: 225 VQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHRE 284
Query: 750 SSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWA 809
S+S RE++ + ERE + + + S G+ R R +
Sbjct: 285 GHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRS-----R 339
Query: 810 KRGRGRGTFQRGRGRFNFKKS--GSSPKWNHDKYQGDGIVEDEEETMENNEEKKDRCKEE 867
R R R +R R R K++ G ++DK +G+ ++ E + E ++E++ R + E
Sbjct: 340 SRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVE 399
Query: 868 KE 869
++
Sbjct: 400 EK 401
Score = 37.0 bits (84), Expect = 0.079
Identities = 34/159 (21%), Positives = 61/159 (38%), Gaps = 10/159 (6%)
Query: 627 SERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRC 686
S+ S + E+ K HR +K +R ER + ++ + R
Sbjct: 389 SKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRS 448
Query: 687 DSADLRHDIDHRRKERSKERGDSKGSRESRG-------SRKQEKTP-KDYKEYKSYKDDS 738
S H K SKE+ + + S+G S+K+E +P K+ +S +
Sbjct: 449 RSRSKEKSSKH--KNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKER 506
Query: 739 KHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKT 777
HKR+ S S S E++ +K+ + + +T
Sbjct: 507 SHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDET 545
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 85.1 bits (209), Expect = 3e-16
Identities = 89/326 (27%), Positives = 132/326 (40%), Gaps = 43/326 (13%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY---RSRSRTYSRSRSRDRMYSRDYRRDYR 60
S SRSHS RS+SRS+ S +SRSRS S K + RSRSR+ SRSRS+ R SR R
Sbjct: 186 SRSRSHS-RSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR--SRSQSRSRS 242
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVS 119
R P + R R + G R + + + G+ +SRSP R +S S
Sbjct: 243 KKEKSRSPSKEKSRSRSHSAGKS----RSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298
Query: 120 SQRSRSRSRRSYRSSRS--PRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPL 177
RSRS+ RR R R S S S+S + GS+ + +++ + + +
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358
Query: 178 KSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQS 237
+S+ + + S S +K + G S T SQS
Sbjct: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAG--------------SSKKKKKEDTDRSQS 404
Query: 238 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRY-----SPSQNSPIHH 292
S S ++ + H+ S +R G G N + S S + +
Sbjct: 405 RSPS-----------RSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPN 453
Query: 293 IPSRRSPAKTIAPQNAPRDESRGRSS 318
+PS A + R +SR RS+
Sbjct: 454 LPSESRSRSKSASKTRSRSKSRSRSA 479
Score = 65.9 bits (159), Expect = 2e-10
Identities = 73/286 (25%), Positives = 112/286 (39%), Gaps = 23/286 (8%)
Query: 99 HSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 158
+ R R + S +RRS S RS SRSR R SR RS S S S +SKS R G
Sbjct: 166 NGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG 225
Query: 159 SQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYD 218
S+ + ++ + + S K KS+ K+ S + +KS A +
Sbjct: 226 SRSRSKSRSRSQSRSRSK-KEKSRSPSKEKSRSRSHSAGKSRSKSKD---------QAEE 275
Query: 219 XSPRSPHSPSPIATPPSQSSSCSDAPMLS---TVHSAKNTPSQHSHSIQHSPERSGSGSV 275
+ + P + PS+ S S + S V K S + S +S S S
Sbjct: 276 KIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSR 335
Query: 276 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFL 335
G SR S++ +R K ++ R SR +S G + +K G
Sbjct: 336 SKGGSR---SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK 392
Query: 336 KRFTDEESRVFLLDRGNTRDKEASKEK---GSEKGRAEGEWEDQEA 378
K+ ++ R + + + SKE+ SE + EG E + A
Sbjct: 393 KKKKEDTDR----SQSRSPSRSVSKEREHAKSESSQREGRGESENA 434
Score = 65.9 bits (159), Expect = 2e-10
Identities = 71/261 (27%), Positives = 95/261 (36%), Gaps = 41/261 (15%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--------------------------RS 36
RS SRS S + KSRS S +SRSRSHS K R
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 37 RSRTYSRSRSRDRMYSRDYRRDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPV-- 94
+S++ SRSRS++R + R R+ + + R R +GG R +
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLR-QSRSRSRSKGGSRSRSRSRSKSKDK 353
Query: 95 -WNRRHSRSPRRGRSRSRSPKRRS----------VSSQRSRSRSRRSYRSSRSP-RSSSS 142
R+ SR R RSRSRS RS S + + + SRSP RS S
Sbjct: 354 RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK 413
Query: 143 RSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNK 202
S+S + RG E E + S KSK + S+ +K
Sbjct: 414 EREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSK 473
Query: 203 SSATCGDIWPGLSAYDXSPRS 223
S + P S RS
Sbjct: 474 SRSRSASRSPSRSRSRSHSRS 494
Score = 59.3 bits (142), Expect = 1e-08
Identities = 89/348 (25%), Positives = 137/348 (39%), Gaps = 57/348 (16%)
Query: 29 SRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHR 88
SR++R SRSR++SRSRSR R +SR
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSR-HSRK---------------------------------- 203
Query: 89 GGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSR-RSYRSSRSPRSSSSRSSSP 147
+R S S + S+SRS RS S RSRS+SR RS SRS + S S
Sbjct: 204 -------SRSRSGSSKSSHSKSRS---RSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKE 253
Query: 148 YSKSPVSKRRGSQEKQTKKAEGELQEESPL-KSKSQEEPKDTFEHDSSESIDEFNKSSAT 206
S+S S+ K +AE ++Q + K KS+ + + S E
Sbjct: 254 KSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEK 313
Query: 207 CGDIWPGLSAYDXSPRSPHSPSPI---ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSI 263
G + G S + S R S S + S+S S S S + + S+ S S
Sbjct: 314 RGSVSRGRS-QEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSR-SRSR 371
Query: 264 QHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDG 323
S GS + + S + RSP+++++ + R+ ++ SS
Sbjct: 372 SKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKE---REHAKSESSQREGR 428
Query: 324 GDQETAKTGKFL--KRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRA 369
G+ E A T + + ++ +S+ L +R K ASK + K R+
Sbjct: 429 GESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRS 476
Score = 44.3 bits (103), Expect = 5e-04
Identities = 46/207 (22%), Positives = 81/207 (39%), Gaps = 17/207 (8%)
Query: 676 ENQKGDKKLRCDSADLRHDID-----HRRKERSKERGDSKGSRESRGSRKQEKTPKDYKE 730
E++ G ++ R S H H RK RS+ G SK S SR + + K
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRS-GSSKSSHSKSRSRSRSGSRSRSKS 232
Query: 731 YKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEM-----KEYS 785
+ S+ K+E+ S S S S S + + +SK + EE+ + + + + S
Sbjct: 233 RSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPS 292
Query: 786 GFAGVSRPRGTFHDDR-DDGVDYWAKRGRG-----RGTFQRGRGRFNFKKSGSSPKWNHD 839
S+ R + R ++ RGR R + R R + + S + D
Sbjct: 293 RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352
Query: 840 KYQGDGIVEDEEETMENNEEKKDRCKE 866
K +G +E + + K +R ++
Sbjct: 353 KRKGRKRSREESRSRSRSRSKSERSRK 379
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/139 (25%), Positives = 61/139 (43%), Gaps = 9/139 (6%)
Query: 643 RQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKER 702
+ +SP H+ S S ++ R+ E+R + +K LR + R R + R
Sbjct: 287 KSRSPSRHKSKSKSRSR-SQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR 345
Query: 703 SK-----ERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSK---HKREQDHSLSSSSSA 754
S+ +R K SRE SR + ++ + + K DSK K+++ S S
Sbjct: 346 SRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR 405
Query: 755 SPSSPSSREEKESKKEREE 773
SPS S+E + +K E +
Sbjct: 406 SPSRSVSKEREHAKSESSQ 424
Score = 40.4 bits (93), Expect = 0.007
Identities = 45/194 (23%), Positives = 75/194 (38%), Gaps = 27/194 (13%)
Query: 629 RFTSYQKATEEHS----TRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKL 684
R S ++ EE +R +S E R S S + +R R ++ +KG K+
Sbjct: 301 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS 360
Query: 685 RCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQ 744
R +S + ERS++RG + S+ S+K++K D + +S +RE
Sbjct: 361 REESRSRSRS--RSKSERSRKRGSKRDSKAG-SSKKKKKEDTDRSQSRSPSRSVSKEREH 417
Query: 745 DHSLSS--------------------SSSASPSSPSSREEKESKKEREEEFKTHHEMKEY 784
S SS S S S S P+ E S+ + + ++ + +
Sbjct: 418 AKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSR 477
Query: 785 SGFAGVSRPRGTFH 798
S SR R H
Sbjct: 478 SASRSPSRSRSRSH 491
Score = 40.0 bits (92), Expect = 0.009
Identities = 58/262 (22%), Positives = 99/262 (37%), Gaps = 44/262 (16%)
Query: 259 HSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSS 318
+S S HS RS S SR S++S H SR ++ R S+ RS
Sbjct: 185 YSRSRSHSRSRSRSRHSRKSRSRSGSSKSS---HSKSRSRSRSGSRSRSKSRSRSQSRS- 240
Query: 319 FYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEA 378
R E+SR ++ +R A K + K +AE + ++ +
Sbjct: 241 ------------------RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDN 282
Query: 379 LDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLA--DQGKSFATASHRNTEEEGLKY 436
+ + + K ++E + R SV Q KS + R+ + G +
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
Query: 437 ------KSKVSLKGNRESDGFREE---------KNDKHKETGYVVERP--STTKDKHKEE 479
KSK KG + S REE K+++ ++ G + S+ K K ++
Sbjct: 343 RSRSRSKSKDKRKGRKRS---REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDT 399
Query: 480 DKNSERITVKKETQSPEQVKSE 501
D++ R + ++ E KSE
Sbjct: 400 DRSQSRSPSRSVSKEREHAKSE 421
Score = 39.7 bits (91), Expect = 0.012
Identities = 74/361 (20%), Positives = 137/361 (37%), Gaps = 51/361 (14%)
Query: 429 TEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKD--------KHKEED 480
TE G K + G+R + ++ + R S ++ K +
Sbjct: 163 TEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS 222
Query: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
++ R K ++S + +S+K K SP ++EKS R S + + + D
Sbjct: 223 RSGSRSRSKSRSRSQSRSRSKKEKSR---SP-------SKEKSRSRSHSAGKSRSKSKDQ 272
Query: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
+++ D+ +P S + R + + S +E+ + K S+ S
Sbjct: 273 AEEKIQNN------DNVGKPKSRSPSRHKSKSKSRSRSQERRV----EEEKRGSVSRGRS 322
Query: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
+ SL K + + S S K+ ++ R++S E R S S
Sbjct: 323 QE-----KSLRQSRSRSRSKGGSRSRSR---SRSKSKDKRKGRKRSREESRSRSRSRSKS 374
Query: 661 RKDTRLAGEERVFKEENQKGDKK-------LRCDSADLRHDIDHRRKERSKE--RGDSKG 711
+ +R G +R K + K KK R S + + +H + E S+ RG+S+
Sbjct: 375 ER-SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESEN 433
Query: 712 SRESRGSRKQEKT-----PKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKE 766
+ ++ +R + ++ P E +S + R + S S S+S SPS SR
Sbjct: 434 AGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Query: 767 S 767
S
Sbjct: 494 S 494
Score = 38.9 bits (89), Expect = 0.021
Identities = 51/265 (19%), Positives = 99/265 (37%), Gaps = 26/265 (9%)
Query: 615 KEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDI---SPSTLRKDTRLAGEER 671
+ Y +S + + S + + + + S KS R S S + +R R
Sbjct: 182 RRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSR 241
Query: 672 VFKEENQKGDK---KLRCDSADLRHDIDHRRKERSKERGDSKGSRESRG-SRKQEKTPKD 727
KE+++ K + R SA + E + D+ G +SR SR + K+
Sbjct: 242 SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR 301
Query: 728 YKEYKSYKDDSK-----HKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMK 782
+ + ++ K R Q+ SL S S S S SR S+ + +++ K +
Sbjct: 302 SRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSR 361
Query: 783 EYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQ 842
E S SR + ++R R RG+ + + + KK + +
Sbjct: 362 EESRSRSRSRSK--------------SERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
Query: 843 GDGIVEDEEETMENNEEKKDRCKEE 867
+ ++ E + +++ R + E
Sbjct: 408 SRSVSKEREHAKSESSQREGRGESE 432
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 84.0 bits (206), Expect = 6e-16
Identities = 208/989 (21%), Positives = 332/989 (33%), Gaps = 220/989 (22%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
RS SRS S S S SS + S+S S R RS SR++SRS SR S Y R
Sbjct: 681 RSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYP---RRG 737
Query: 63 RAMRRPYGYRGRGRGYYQGGGGRYHRGGYR-PVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 121
R R Y R R G YHR R P + R HSRS R +SP +R+V
Sbjct: 738 RGKSRNYRSRSRSHG--------YHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQG 789
Query: 122 RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKS 181
+ YR P + Y +S + P + +
Sbjct: 790 ETEREYFNRYREVPPPYDMKAY----YGRS-------------------VDFRDPFEKER 826
Query: 182 QEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCS 241
E +E E +++ K A P + + SP P I P
Sbjct: 827 YRE----WERKYREWYEKYYKGYAAGAQPRPSANRENFSPER-FLPLNIRNSPFTRGRRE 881
Query: 242 DAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAK 301
D + H ++N S + + R G N S+ S+N+P
Sbjct: 882 DY-VGGQSHRSRNIGSNYPEKLS---ARDGHNQKDNTKSKEKESENAP------------ 925
Query: 302 TIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKE 361
GD + K K KR EES FL N E S++
Sbjct: 926 ----------------------GDGKGNKHKKHRKRRKGEESEGFL----NPELLETSRK 959
Query: 362 KGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEG---DDTEETEDYRQFRKSVLADQG 418
G E + + L D + + D+E E + + + D+
Sbjct: 960 SREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKT 1019
Query: 419 KSFATASHRNTEEEGLKYKS--KVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKH 476
K S + +E +K + + G RE E K KE E P T K
Sbjct: 1020 KRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKE-----ETPKTDNTKS 1074
Query: 477 KEEDKNSERIT---------VKKETQSPEQVKSEKLKDLFDYS----------------- 510
+ E+IT KE Q + VK EK+K DYS
Sbjct: 1075 SSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKK--DYSKDVKSEKLTTKEEKAKK 1132
Query: 511 -----PPLHKNLDAREKSTFR-------EESPLRI-KMIASDSHRPEVKLKMAPVPLDDS 557
PL + R++ T E S ++I K+ ++ +P K KM P D
Sbjct: 1133 PNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEP---DTE 1189
Query: 558 NRPASLTKDRLLASTLVHSVKKEQE-------FRSIFDHIKLPQASKSTSESFIQHIV-- 608
+ KD++ S +K +E +I + + + +STS Q V
Sbjct: 1190 KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKG 1249
Query: 609 --------------SLVHHVKEQYFKSAAMTLSERFTSYQ----KATEEHSTRQKSP--E 648
+LV + + + SE T + K EE++ +P +
Sbjct: 1250 KVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAED 1309
Query: 649 IHRRIDISPSTLRKDTRLAGEERV----------------------------FKEENQKG 680
+ I + S KD + EE V + E+ +
Sbjct: 1310 VIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEP 1369
Query: 681 DKKLRCDSAD-----LRHDIDHRRKERSKERGDSKG------SRESRGSRKQEKTPK--- 726
+K++ + D ++H++ + S E+G +K +E+ RK P+
Sbjct: 1370 SEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKES 1429
Query: 727 ------DYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
+ +KS SK R D S+ +S++ +R++K RE +
Sbjct: 1430 NLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRD 1489
Query: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDK 840
K ++R + + ++D K R ++G G + KKS SSP +
Sbjct: 1490 EKN-----ELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTG--DSKKSNSSPSRDRKP 1542
Query: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869
+ + + E K+ CK+ ++
Sbjct: 1543 HDHKATYDTKRPNEETKSVDKNPCKDREK 1571
Score = 72.8 bits (177), Expect = 1e-12
Identities = 146/749 (19%), Positives = 296/749 (39%), Gaps = 110/749 (14%)
Query: 101 RSPRRG----RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--------- 147
RSPR +++ +PK + +S S S++ + + +PR + S+S+
Sbjct: 1051 RSPRSEPPIKKAKEETPK---TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1107
Query: 148 ------YSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFN 201
YSK S++ ++E++ KK ++ PL +K ++ + T E + +D+
Sbjct: 1108 EKVKKDYSKDVKSEKLTTKEEKAKKPN---EKNKPLDNKGEKRKRKTEE----KGVDKDF 1160
Query: 202 KSSATCGDIWPGLSAYDXSPR---SPHSPSPIATPPSQSSSCSDAPM------------L 246
+SS+ SP+ P + TP S S AP +
Sbjct: 1161 ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLS-APAKKIKLNRETGKKI 1219
Query: 247 STVHSAKNT--PSQHSHS---------IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPS 295
+ + NT PS+ S ++ R +G+ G+ S+ + S P
Sbjct: 1220 GSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPV 1279
Query: 296 RRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRD 355
R+S KT D R + + TA + +S+ + D
Sbjct: 1280 RKSEEKT--------DTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK------WDKDD 1325
Query: 356 KEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLA 415
E+ +E + + S K S K+ + E +E +E ++F K V
Sbjct: 1326 FESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---SEPSEKIQKFTKDVSH 1382
Query: 416 D-------QGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN-DKHKETGYVVE 467
+ K+ A++ T++ K + + + S +E N D+ E G
Sbjct: 1383 EIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKS 1442
Query: 468 RPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE 527
++K+ + +S R + K+ K++ D +YS K D + + T R+
Sbjct: 1443 LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY--DTREYSSS--KRRDEKNELTRRK 1498
Query: 528 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 587
+SP R K AS P ++ + P T D +++ +K + ++ +
Sbjct: 1499 DSPSRNKDSASGQKNK---------PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATY 1549
Query: 588 DHIKLPQASKSTSESFIQ----HIVSLVHHVKEQYFKSAAMTLSERFTSYQK----ATEE 639
D + + +KS ++ + H++ ++ KE L+ T +K +
Sbjct: 1550 DTKRPNEETKSVDKNPCKDREKHVLEARNN-KESSGNKLLYILNPPETQVEKEQITGQID 1608
Query: 640 HSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCD--SADLRHDIDH 697
ST + P++ +S S L ++T A E + E + + + ++ + S ++ D+
Sbjct: 1609 KSTVKPKPQLSHSSRLS-SDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKD 1667
Query: 698 RRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPS 757
+ E++KE D+ + SR Q + +S+ R S SSS+S++ S
Sbjct: 1668 KIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTR----SHSSSASSAES 1723
Query: 758 SPSSREEKESKKEREEEFKTHHEMKEYSG 786
S +++K+ +K++ ++ K H + K+++G
Sbjct: 1724 QDSKKKKKKKEKKKHKKHKKHKKHKKHAG 1752
Score = 46.2 bits (108), Expect = 1e-04
Identities = 66/299 (22%), Positives = 115/299 (38%), Gaps = 27/299 (9%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSH-----SRKKRYRSRSRTYSRSRSRDRMYSRDYR 56
G S S SS+ S +R+ S+ +R K+ +R YS S+ RD R
Sbjct: 1438 GNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRR 1497
Query: 57 RD--YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 114
+D RN + R + G G + P +R+ ++ + +
Sbjct: 1498 KDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEE 1557
Query: 115 RRSVSSQRSRSRSRRSYRSSRSPRSSSSR----SSSPYSKSPVSKRRGSQEKQTKKAEGE 170
+SV + R + + + SS ++ + P ++ + G +K T K + +
Sbjct: 1558 TKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQ 1617
Query: 171 LQEESPLKSK-SQEEPKDTFEHDSSESIDEFN---KSSATCGDIWPGL--SAYDXSPRSP 224
L S L S ++E + FE D +ES E N K + G+I L + + S
Sbjct: 1618 LSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESL 1677
Query: 225 HSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYS 283
+ + + S++ S HS+ + SHS S RS S S + S+ S
Sbjct: 1678 DTAAVVQVGISRNQS----------HSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDS 1726
Score = 45.1 bits (105), Expect = 3e-04
Identities = 85/435 (19%), Positives = 171/435 (39%), Gaps = 62/435 (14%)
Query: 94 VWNRRHSRSPRRGRSRSR--------SPKRRSVSSQRSRSRS-----RRSYRSSRSPRSS 140
V + ++S S +G+++ R +P++R S+Q + + + S S S
Sbjct: 1389 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1448
Query: 141 SSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEF 200
+R+S + + S + + KK + + +E S SK ++E + S S
Sbjct: 1449 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYS--SSKRRDEKNELTRRKDSPSR--- 1503
Query: 201 NKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT----- 255
NK SA S PR T S+ S+ S + H K T
Sbjct: 1504 NKDSA---------SGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKP-HDHKATYDTKR 1553
Query: 256 PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRG 315
P++ + S+ +P + V + S N ++ + +P +T +++ G
Sbjct: 1554 PNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYIL----NPPET----QVEKEQITG 1605
Query: 316 ---RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGE 372
+S+ P +++ L R TDE + + ++ + KE+ S G +
Sbjct: 1606 QIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS-GNISKD 1664
Query: 373 WEDQ------EALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASH 426
+D+ E+LD + + G + + + S Q +S ++++
Sbjct: 1665 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH-----SPSGSQTRSHSSSAS 1719
Query: 427 RNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKE-TGYVVERPSTTKDKHKEEDKNSER 485
++ K K K K ++ + +K+ KHK+ G VE + K KHK++ +
Sbjct: 1720 SAESQDSKKKKKKKEKKKHK-----KHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNK 1774
Query: 486 ITVKKETQSPEQVKS 500
K++ + ++VKS
Sbjct: 1775 DKEKEKEKDDQKVKS 1789
Score = 35.4 bits (80), Expect = 0.23
Identities = 86/417 (20%), Positives = 138/417 (33%), Gaps = 84/417 (20%)
Query: 14 KSRSQSSSRSR-SRSHSRKKRYRSRSRTYSRSRSRD---RMYSRDYRRDYRNNRAMRRPY 69
KS SQSS +R S H + ++ T +R + D R YS RRD +N R+
Sbjct: 1441 KSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDS 1500
Query: 70 GYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRR 129
R + Q R R P++G S+ S S R +
Sbjct: 1501 PSRNKDSASGQKNKPREERD------------LPKKGTGDSKK-SNSSPSRDRKPHDHKA 1547
Query: 130 SYRSSRSPRSSSSRSSSPYS--KSPVSKRRGSQEKQTKK---------AEGELQEESPLK 178
+Y + R + S +P + V + R ++E K + E ++ +
Sbjct: 1548 TYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQI 1607
Query: 179 SKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSS 238
KS +PK H S S D ++ +A++ S S ++ +SS
Sbjct: 1608 DKSTVKPKPQLSHSSRLSSDLTRETDE---------AAFEPDYNESDSESNVSVKEEESS 1658
Query: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG--NGSSRYSPSQNSPIHHIPSR 296
+ +K+ + + S + + VG S SPS + H PS
Sbjct: 1659 G----------NISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSG 1708
Query: 297 RSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDK 356
++R SS Q++ K K K
Sbjct: 1709 --------------SQTRSHSSSASSAESQDSKKKKK---------------------KK 1733
Query: 357 EASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSV 413
E K K +K + + E S K K+K + D +E E Q KSV
Sbjct: 1734 EKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV 1790
Score = 30.8 bits (68), Expect = 5.7
Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 1 MGRSNSRSHSSRS--KSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58
+G S ++SHSS S SRS S S S++RSHS + + + +++ + +++
Sbjct: 1685 VGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKH 1744
Query: 59 YRNNR 63
++ +
Sbjct: 1745 KKHKK 1749
Score = 30.0 bits (66), Expect = 9.7
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Query: 511 PPLHKNLDAREKSTF-REESPLRIKMIASDSH-RPEVKLKMA-------PVPLDDSNRPA 561
P + +NL +S R++ PL I + +S +H P + + PV + S+ PA
Sbjct: 348 PLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPA 407
Query: 562 SLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSES 602
+ S VHS K + FR D+ LP A+ ++ S
Sbjct: 408 PVPDITATVSISVHSEKSDGPFRD-SDNKILPAAALASEHS 447
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 83.6 bits (205), Expect = 7e-16
Identities = 186/948 (19%), Positives = 332/948 (35%), Gaps = 161/948 (16%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSR-----------KKRYRSRSRTYSRSRSRDRMYS 52
S SRS S+RS+S S+S SRS SRS+SR + YRSRSR++ RSR R S
Sbjct: 669 SKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSR--S 726
Query: 53 RDYRRDYRNNRAMRRPYGYRGRG---RGYYQGGGGRYHRGGYRPV--------------- 94
YRR + +R+ P +RG+ R QG R + YR V
Sbjct: 727 PPYRRYHSRSRS---PQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVD 783
Query: 95 -------------------WNRRHSRSPRRGRSRSRSPKRRSVSSQR-----------SR 124
W ++ + G S R + S +R +R
Sbjct: 784 FRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTR 843
Query: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEE 184
R R Y +S RS + S+ P +S R G +K K++ + E +P K +
Sbjct: 844 GR-REDYVGGQSHRSRNIGSNYP---EKLSARDGHNQKDNTKSKEKESENAPGDGKGNKH 899
Query: 185 PKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAP 244
K ES G + S S P +++ S P
Sbjct: 900 KKHRKRRKGEES---------------EGFLNPELLETSRKSREPTGVEENKTDSLFVLP 944
Query: 245 MLSTVHSAKNTP----SQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
++ P S S+ +R G + S + + PA
Sbjct: 945 SRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPA 1004
Query: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
K + E RS +ET KT + ++ ++ ++A
Sbjct: 1005 KGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKD-----EKITGTPRKAHS 1059
Query: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
+ E + E++ DY D +S K + + E
Sbjct: 1060 KSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNE------------------ 1101
Query: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEED 480
++ + +G K K K KG + K K + T V P K K + +
Sbjct: 1102 ----KNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSP---KRKMEPDT 1154
Query: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
+ +R K + K KL + K + + E + +E +++ +S
Sbjct: 1155 EKMDRTPEKDKISLSAPAKKIKL------NRETGKKIGSTENISNTKEPSEKLESTSSKV 1208
Query: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQE----FRSIFDHIKLPQAS 596
+ +VK K+ ++L +ST V+K +E R++ IK +
Sbjct: 1209 KQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTV---IKTMEEY 1265
Query: 597 KSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDIS 656
+ + + + ++ ++ + ++ K + E K+T+ S+ K + + +
Sbjct: 1266 NNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDV----KSTQPISSVGKPASVIKNVSTK 1321
Query: 657 PSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKG----- 711
PS + K E E+ QK K + + ++H++ + S E+G +K
Sbjct: 1322 PSNIVKYPEKESEP---SEKIQKFTKDVSHEI--IQHEVKSSKNSASSEKGKTKDRDYSV 1376
Query: 712 -SRESRGSRKQEKTPK---------DYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSS 761
+E+ RK P+ + +KS SK R D S+ +S++ +
Sbjct: 1377 LEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPN 1436
Query: 762 REEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRG 821
R++K RE + K ++R + + ++D K R ++G
Sbjct: 1437 RDKKTDYDTREYSSSKRRDEKN-----ELTRRKDSPSRNKDSASGQKNKPREERDLPKKG 1491
Query: 822 RGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKKDRCKEEKE 869
G + KKS SSP + + + + E K+ CK+ ++
Sbjct: 1492 TG--DSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREK 1537
Score = 72.8 bits (177), Expect = 1e-12
Identities = 146/749 (19%), Positives = 296/749 (39%), Gaps = 110/749 (14%)
Query: 101 RSPRRG----RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--------- 147
RSPR +++ +PK + +S S S++ + + +PR + S+S+
Sbjct: 1017 RSPRSEPPIKKAKEETPK---TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1073
Query: 148 ------YSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFN 201
YSK S++ ++E++ KK ++ PL +K ++ + T E + +D+
Sbjct: 1074 EKVKKDYSKDVKSEKLTTKEEKAKKPN---EKNKPLDNKGEKRKRKTEE----KGVDKDF 1126
Query: 202 KSSATCGDIWPGLSAYDXSPR---SPHSPSPIATPPSQSSSCSDAPM------------L 246
+SS+ SP+ P + TP S S AP +
Sbjct: 1127 ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLS-APAKKIKLNRETGKKI 1185
Query: 247 STVHSAKNT--PSQHSHS---------IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPS 295
+ + NT PS+ S ++ R +G+ G+ S+ + S P
Sbjct: 1186 GSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPV 1245
Query: 296 RRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRD 355
R+S KT D R + + TA + +S+ + D
Sbjct: 1246 RKSEEKT--------DTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK------WDKDD 1291
Query: 356 KEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLA 415
E+ +E + + S K S K+ + E +E +E ++F K V
Sbjct: 1292 FESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---SEPSEKIQKFTKDVSH 1348
Query: 416 D-------QGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN-DKHKETGYVVE 467
+ K+ A++ T++ K + + + S +E N D+ E G
Sbjct: 1349 EIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKS 1408
Query: 468 RPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE 527
++K+ + +S R + K+ K++ D +YS K D + + T R+
Sbjct: 1409 LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY--DTREYSSS--KRRDEKNELTRRK 1464
Query: 528 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 587
+SP R K AS P ++ + P T D +++ +K + ++ +
Sbjct: 1465 DSPSRNKDSASGQKNK---------PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATY 1515
Query: 588 DHIKLPQASKSTSESFIQ----HIVSLVHHVKEQYFKSAAMTLSERFTSYQK----ATEE 639
D + + +KS ++ + H++ ++ KE L+ T +K +
Sbjct: 1516 DTKRPNEETKSVDKNPCKDREKHVLEARNN-KESSGNKLLYILNPPETQVEKEQITGQID 1574
Query: 640 HSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCD--SADLRHDIDH 697
ST + P++ +S S L ++T A E + E + + + ++ + S ++ D+
Sbjct: 1575 KSTVKPKPQLSHSSRLS-SDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKD 1633
Query: 698 RRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPS 757
+ E++KE D+ + SR Q + +S+ R S SSS+S++ S
Sbjct: 1634 KIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTR----SHSSSASSAES 1689
Query: 758 SPSSREEKESKKEREEEFKTHHEMKEYSG 786
S +++K+ +K++ ++ K H + K+++G
Sbjct: 1690 QDSKKKKKKKEKKKHKKHKKHKKHKKHAG 1718
Score = 45.1 bits (105), Expect = 3e-04
Identities = 85/435 (19%), Positives = 171/435 (39%), Gaps = 62/435 (14%)
Query: 94 VWNRRHSRSPRRGRSRSR--------SPKRRSVSSQRSRSRS-----RRSYRSSRSPRSS 140
V + ++S S +G+++ R +P++R S+Q + + + S S S
Sbjct: 1355 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1414
Query: 141 SSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEF 200
+R+S + + S + + KK + + +E S SK ++E + S S
Sbjct: 1415 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYS--SSKRRDEKNELTRRKDSPSR--- 1469
Query: 201 NKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT----- 255
NK SA S PR T S+ S+ S + H K T
Sbjct: 1470 NKDSA---------SGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKP-HDHKATYDTKR 1519
Query: 256 PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRG 315
P++ + S+ +P + V + S N ++ + +P +T +++ G
Sbjct: 1520 PNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYIL----NPPET----QVEKEQITG 1571
Query: 316 ---RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGE 372
+S+ P +++ L R TDE + + ++ + KE+ S G +
Sbjct: 1572 QIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS-GNISKD 1630
Query: 373 WEDQ------EALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASH 426
+D+ E+LD + + G + + + S Q +S ++++
Sbjct: 1631 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH-----SPSGSQTRSHSSSAS 1685
Query: 427 RNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKE-TGYVVERPSTTKDKHKEEDKNSER 485
++ K K K K ++ + +K+ KHK+ G VE + K KHK++ +
Sbjct: 1686 SAESQDSKKKKKKKEKKKHK-----KHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNK 1740
Query: 486 ITVKKETQSPEQVKS 500
K++ + ++VKS
Sbjct: 1741 DKEKEKEKDDQKVKS 1755
Score = 35.4 bits (80), Expect = 0.23
Identities = 86/417 (20%), Positives = 138/417 (33%), Gaps = 84/417 (20%)
Query: 14 KSRSQSSSRSR-SRSHSRKKRYRSRSRTYSRSRSRD---RMYSRDYRRDYRNNRAMRRPY 69
KS SQSS +R S H + ++ T +R + D R YS RRD +N R+
Sbjct: 1407 KSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDS 1466
Query: 70 GYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRR 129
R + Q R R P++G S+ S S R +
Sbjct: 1467 PSRNKDSASGQKNKPREERD------------LPKKGTGDSKK-SNSSPSRDRKPHDHKA 1513
Query: 130 SYRSSRSPRSSSSRSSSPYS--KSPVSKRRGSQEKQTKK---------AEGELQEESPLK 178
+Y + R + S +P + V + R ++E K + E ++ +
Sbjct: 1514 TYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQI 1573
Query: 179 SKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSS 238
KS +PK H S S D ++ +A++ S S ++ +SS
Sbjct: 1574 DKSTVKPKPQLSHSSRLSSDLTRETDE---------AAFEPDYNESDSESNVSVKEEESS 1624
Query: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG--NGSSRYSPSQNSPIHHIPSR 296
+ +K+ + + S + + VG S SPS + H PS
Sbjct: 1625 G----------NISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSG 1674
Query: 297 RSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDK 356
++R SS Q++ K K K
Sbjct: 1675 --------------SQTRSHSSSASSAESQDSKKKKK---------------------KK 1699
Query: 357 EASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSV 413
E K K +K + + E S K K+K + D +E E Q KSV
Sbjct: 1700 EKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV 1756
Score = 30.8 bits (68), Expect = 5.7
Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 1 MGRSNSRSHSSRS--KSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58
+G S ++SHSS S SRS S S S++RSHS + + + +++ + +++
Sbjct: 1651 VGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKH 1710
Query: 59 YRNNR 63
++ +
Sbjct: 1711 KKHKK 1715
Score = 30.0 bits (66), Expect = 9.7
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Query: 511 PPLHKNLDAREKSTF-REESPLRIKMIASDSH-RPEVKLKMA-------PVPLDDSNRPA 561
P + +NL +S R++ PL I + +S +H P + + PV + S+ PA
Sbjct: 348 PLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPA 407
Query: 562 SLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSES 602
+ S VHS K + FR D+ LP A+ ++ S
Sbjct: 408 PVPDITATVSISVHSEKSDGPFRD-SDNKILPAAALASEHS 447
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 81.6 bits (200), Expect = 3e-15
Identities = 71/202 (35%), Positives = 89/202 (44%), Gaps = 40/202 (19%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
MGR SR + RS SR +S SRSRSRS S K+ R R SRSR RDR R RD R
Sbjct: 1 MGRE-SRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRR-SRSRDRDRRRERSRSRDKR 58
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
+R+ R R R R R R R RSRS RR
Sbjct: 59 RSRSRDRKRLRRSRSR-----------------------ERDRSRERRRSRSRDRR---R 92
Query: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSK 180
RSRSR RR SRSSSP +KS ++ R +++T E +++ K
Sbjct: 93 SRSRSRGRR------------SRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDK 140
Query: 181 SQEEPKDTFEHDSSESIDEFNK 202
E+ KD D ++ +E K
Sbjct: 141 EDEKEKDAGNFDQNKLEEEMRK 162
Score = 61.6 bits (148), Expect = 3e-09
Identities = 60/203 (29%), Positives = 81/203 (39%), Gaps = 25/203 (12%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
RS SR R + RS+S + RSRS RK+ RSRSR RSR R R SRD RR
Sbjct: 39 RSRSRDRDRR-RERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRS-- 95
Query: 63 RAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 122
R RGR G + NR S+ G S+ K+ +
Sbjct: 96 ---------RSRGRRSRSSSPGNKS----KKTENRSRSKEKTDGGESSKEKKKDKDDKED 142
Query: 123 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQ---EESPLKS 179
+ + ++ ++ R K V K R Q K+ + GEL+ EE
Sbjct: 143 EKEKDAGNFDQNKLEEEMRKR------KERVEKWREEQRKKAMENIGELKKEIEEMKQGK 196
Query: 180 KSQEEPKDTFEHDSSESIDEFNK 202
K E D E D +E+ E N+
Sbjct: 197 KWSLEDDDDDEDDPAEAEKEGNE 219
Score = 41.6 bits (96), Expect = 0.003
Identities = 48/240 (20%), Positives = 95/240 (39%), Gaps = 44/240 (18%)
Query: 629 RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDS 688
R S +++ R +S + RR + S S ++ +R +R+ + +++ D+
Sbjct: 25 RSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRE--- 81
Query: 689 ADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSL 748
RR+ RS++R S+ SRG R + +P + + + SK K
Sbjct: 82 ---------RRRSRSRDRRRSRS--RSRGRRSRSSSPGNKSKKTENRSRSKEK------- 123
Query: 749 SSSSSASPSSPSSREEKESKKERE----EEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDG 804
+ +S +++KE +KE++ ++ K EM++ R +
Sbjct: 124 TDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRK-----------------RKER 166
Query: 805 VDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWN--HDKYQGDGIVEDEEETMENNEEKKD 862
V+ W + R + G + ++ KW+ D D E E+E E E+ D
Sbjct: 167 VEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELD 226
Score = 40.0 bits (92), Expect = 0.009
Identities = 48/173 (27%), Positives = 68/173 (39%), Gaps = 34/173 (19%)
Query: 697 HRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASP 756
H RK RS RG S GSR + ++P D K K D R++D S S
Sbjct: 7 HYRK-RSASRGRS-------GSRSRSRSPSD-KRSKRGDDRRSRSRDRDRRRERSRSRDK 57
Query: 757 SSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRG 816
SR+ K ++ R E E + SR R DR +R R R
Sbjct: 58 RRSRSRDRKRLRRSRSRERDRSRERRR-------SRSR-----DR--------RRSRSRS 97
Query: 817 TFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKKDRCKEEKE 869
+R R KS + + K + DG E + E ++K D+ ++EKE
Sbjct: 98 RGRRSRSSSPGNKSKKTENRSRSKEKTDG----GESSKEKKKDKDDK-EDEKE 145
Score = 35.8 bits (81), Expect = 0.18
Identities = 67/313 (21%), Positives = 117/313 (37%), Gaps = 67/313 (21%)
Query: 295 SRRSPAKTIAPQN-APRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNT 353
SR +++ +P N + + E+R RS DGG+ K K+ D++ D GN
Sbjct: 97 SRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEK-----KKDKDDKEDEKEKDAGNF 151
Query: 354 RDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSV 413
+ +E K R E +W +++ ++K ++ G+ +E E+ +Q +K
Sbjct: 152 DQNKLEEEMRKRKERVE-KWREEQ-----------RKKAMENIGELKKEIEEMKQGKKWS 199
Query: 414 LADQGKSF---ATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPS 470
L D A A E EG + D + EE ++ K+
Sbjct: 200 LEDDDDDEDDPAEAEKEGNEMEGEELD---------PLDAYMEEVKEEVKKFNM-----R 245
Query: 471 TTKDKHKEEDKNSERIT--VKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREE 528
+ K E K+ +T V T V S+K K + + DA E S+ EE
Sbjct: 246 SVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKK-----GELMENDQDAMEYSSEEEE 300
Query: 529 SPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFD 588
L+ + TK R L + H + + FR F
Sbjct: 301 VDLQTALTGYQ------------------------TKQRKLLEPVDHGKIEYEPFRKNF- 335
Query: 589 HIKLPQASKSTSE 601
++++P+ +K + E
Sbjct: 336 YVEVPELAKMSQE 348
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 81.6 bits (200), Expect = 3e-15
Identities = 158/808 (19%), Positives = 280/808 (34%), Gaps = 90/808 (11%)
Query: 2 GRSNSRSHSSRSKSRS-----QSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYR 56
GR R R K RS Q S SR HS + S + +S S R R S Y+
Sbjct: 301 GRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQ 360
Query: 57 RDYRNN-RAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSR-SPRRGRSRSRSPK 114
R R PY + R HR R H R S R R
Sbjct: 361 RTLTPPLRRSASPYPSHSLSSPQRKQSPPR-HRSPMREKGRHDHERTSQSHDRRHERRED 419
Query: 115 RRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEE 174
R + SR R Y +S P R +++++ + ++++
Sbjct: 420 TRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDS 479
Query: 175 SPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPP 234
++ S++ + DS + D + D Y RS + + +
Sbjct: 480 REMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRS-YGRNHLREES 538
Query: 235 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIP 294
S++ +++ S + + + PE+ GS GS S S NS H
Sbjct: 539 SRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGS--RGSQIDSHSSNSNYHDSW 596
Query: 295 SRRS--PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKT--------------GKFLKRF 338
RS P + P+ RD++R SSF G+++ G+ +
Sbjct: 597 ETRSSYPERDRYPERDNRDQARD-SSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELE 655
Query: 339 TDEESRVFLLDRGNTRDKEASKEKGSEKGR-AEGEWEDQEALDYFSDKESGKQKFNDSEG 397
DE +DR + R E ++E+ E+ R E E E + D +KE ++ E
Sbjct: 656 RDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARER 715
Query: 398 DDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKND 457
+ E E R+ + D+ + R E E + + + + RE + RE + +
Sbjct: 716 EREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERE 775
Query: 458 KHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNL 517
+ +E ER +DK K D E+ +E ++P E+
Sbjct: 776 RARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDER--------------- 820
Query: 518 DAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSV 577
+ K +R E +P P R + D S +S
Sbjct: 821 --KSKKRYRNEG--------------------SPSPRQSPKRRREHSPD----SDAYNSG 854
Query: 578 KKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKAT 637
+ E + + PQ S+S S S + KE+ K S R+
Sbjct: 855 DDKNEKHRLLSQVVRPQESRSLSPSHLTE--DRQGRWKEEDRKPERKESSRRY------- 905
Query: 638 EEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDH 697
EE ++K + ++ R+ T + R+ ++ + +++D HD ++
Sbjct: 906 EEQELKEKVSSVDKQ--------REQTEILESSRMRAQDIIGHHQSEDRETSDRAHD-EN 956
Query: 698 RRKERSKERGDSKGSRESRGSRKQ--EKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSAS 755
++K + +++ K + G + E T +D + + K K E+ S S
Sbjct: 957 KKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDI 1016
Query: 756 PSSPSSREEKESKKEREEEFKTHHEMKE 783
++++ K+ + R T E+ E
Sbjct: 1017 SDEEAAQQSKKKRGPRTPPITTKEELVE 1044
Score = 68.2 bits (165), Expect = 3e-11
Identities = 160/744 (21%), Positives = 270/744 (36%), Gaps = 91/744 (12%)
Query: 107 RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKK 166
R S+SPKR+S S S+ R + SP R+S K+ SK++G + T
Sbjct: 213 RKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNS----KTNQSKKKGPR---TPS 265
Query: 167 AEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSP-- 224
+ E+ L K +E+ K + I+E + G + PRS
Sbjct: 266 PPPPIPEDIALGKKYKEKYK------VKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSP 319
Query: 225 ----HSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS-QHSHSIQHSPERSGSGSVGNGS 279
HSP S S S S S K TPS + ++ RS S +
Sbjct: 320 AGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSL 379
Query: 280 SRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFT 339
S Q+ P H P R R + S + ++ GK +
Sbjct: 380 SSPQRKQSPPRHRSPMREKG----------RHDHERTSQSHDRRHERREDTRGKRDREKD 429
Query: 340 DEESRVFLLDRGNTRDKEASKEKGSEKGRAEG-EWEDQEALDYFSDKESGKQKFNDSEGD 398
E R + D+ ++RD +E + R + + D+ L D ++ + S
Sbjct: 430 SREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR-- 487
Query: 399 DTEETEDYRQFRKSVLA-DQGKSFATASHRNTE---EEGLKY--------KSKVSLKGNR 446
DT+E+ D R R + A D +HR + EE Y S+ ++
Sbjct: 488 DTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNES 547
Query: 447 ESDGFREEKNDKH-KETGYVVERPSTTK--------DKHKEE----DKNSERITVKKETQ 493
++ E +ND+ + G V E P D H D R + + +
Sbjct: 548 RNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDR 607
Query: 494 SPEQVKSEKLKDL-FDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPV 552
PE+ ++ +D F+ D RE+ R SP+R + + R E + +
Sbjct: 608 YPERDNRDQARDSSFERRHGERDRRDNRERDQ-RPSSPIRHQGRNDELERDERREERRVD 666
Query: 553 PLDDSN------RPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQH 606
+DD R +DR +E+E + + + + + +
Sbjct: 667 RVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726
Query: 607 IVSLVHHVKEQYFKSAAMTLSERFTSYQKATE-EHSTRQKSPEIHRRIDISPSTLRKDTR 665
H +E+ ER +K E E R++ E R + R+ R
Sbjct: 727 RDRDRDHDRERE--------RERERDREKEREREREERERERERERERERERERERERAR 778
Query: 666 LAGEERVFK---EENQKGDKKLRCDSADLRHDIDHRR---KERSKERGDSKGSRESRGS- 718
+ER + E+ KG R ++R D + R + +SK+R ++GS R S
Sbjct: 779 ERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSP 838
Query: 719 -RKQEKTPKDYKEYKSYKD-DSKHK------REQDHSLSSSSSASPSSPSSREEKESKKE 770
R++E +P D Y S D + KH+ R Q+ S S + +E++ K E
Sbjct: 839 KRRREHSP-DSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPE 897
Query: 771 REEEFKTHHEMKEYSGFAGVSRPR 794
R+E + + E + + V + R
Sbjct: 898 RKESSRRYEEQELKEKVSSVDKQR 921
Score = 58.5 bits (140), Expect = 3e-08
Identities = 158/848 (18%), Positives = 296/848 (34%), Gaps = 145/848 (17%)
Query: 69 YGYRGRGRGYYQGGGGRYHRGGYRPVWNRRH----------SRSPRRGRSRSRSPKRRSV 118
+G RG+GY Y R RP + R + +R S SP R+
Sbjct: 61 HGPSPRGKGY----SSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKES 116
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLK 178
S R R + R+P S V + + E L+
Sbjct: 117 SRGRHREKEDIKITKERTPESEEEN---------VEWETNRDDSDNGDINYDYVHELSLE 167
Query: 179 SKSQEEPKDTF--EHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQ 236
K Q+ ++ E ++ E +E ++ RS SPSP S+
Sbjct: 168 MKRQKIQRELMKLEQENMEKREEIIIKKEVSPEV----------VRSKLSPSPSLRKSSK 217
Query: 237 SSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSR 296
S +P S+ S S + S + N S + P SP IP
Sbjct: 218 SPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKT----NQSKKKGPRTPSPPPPIPED 273
Query: 297 RSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDK 356
+ K + +D +E + GK DRG RD
Sbjct: 274 IALGKKYKEKYKVKDRI------------EEKTRDGK---------------DRG--RDF 304
Query: 357 EASKEKGSEKGRAEGEWEDQEALD---YFSDKESGK--QKFNDSEGDDTEETEDYRQ--- 408
E +EK + + + + S +SG Q+ + S + Y++
Sbjct: 305 ERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLT 364
Query: 409 --FRKSV-------LADQGKSFATASHRNT-EEEGLKYKSKVSLKGNRESD------GFR 452
R+S L+ + + HR+ E+G + S +R + G R
Sbjct: 365 PPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKR 424
Query: 453 EEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEK----LKDLFD 508
+ + D +E Y ++ S+ + E ++ ++T+ +++ + +++ D
Sbjct: 425 DREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRD 484
Query: 509 YSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRL 568
YS ++ D R+ + R+ R + D+HR E D+ S + R
Sbjct: 485 YSRDTKESRDPRDSRSTRDAHDYRDRE-GRDTHRKE-----------DTYPEESRSYGR- 531
Query: 569 LASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSE 628
+ +E+ R+ I+ ++S SE + V E K + +
Sbjct: 532 -------NHLREESSRT---EIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGS 581
Query: 629 RFTSYQKATEEHS---TRQKSPEIHRRIDISPSTLRKDT---RLAGEE--RVFKEENQKG 680
+ S+ + H TR PE R + +D+ R GE R +E +Q+
Sbjct: 582 QIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRP 641
Query: 681 DKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKH 740
+R + + D RR+ER +R D + R+ R + + +D + + + +
Sbjct: 642 SSPIRHQGRNDELERDERREERRVDRVDDR--RDERARERDRERERDRERERERERERDR 699
Query: 741 KREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDD 800
+RE++ L + EKE +ER+ + + H +E + R ++
Sbjct: 700 EREKERELERERA---REREREREKERDRERDRD-RDHDRERERERERDREKEREREREE 755
Query: 801 RDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEK 860
R+ + +R R R +R R R K+ W ED+++ ++ EK
Sbjct: 756 RERERERERERERERER-ERERARERDKERERQRDW-----------EDKDKGRDDRREK 803
Query: 861 KDRCKEEK 868
++ +E++
Sbjct: 804 REEIREDR 811
Score = 55.8 bits (133), Expect = 2e-07
Identities = 152/817 (18%), Positives = 276/817 (33%), Gaps = 134/817 (16%)
Query: 7 RSHSSRSKSRSQSSSRSRSRSHSRKK-RYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRAM 65
R +R + R + R R R R++ R R + R R R+R+R R+ RD +R
Sbjct: 672 RDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR-- 729
Query: 66 RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRS 125
R H +R R R R + R +R +R R
Sbjct: 730 ------------------DRDH--------DRERERERERDREKEREREREERERERERE 763
Query: 126 RSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEP 185
R R R R+ + K +G +++ K+ E ++ +P + +
Sbjct: 764 RERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIR-EDRNPRDGHDERKS 822
Query: 186 KDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPM 245
K + ++ S S + K ++ D S + P S
Sbjct: 823 KKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRS------- 875
Query: 246 LSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQ-NSPIHHIPSRRSPAKTIA 304
LS H ++ + PER S S RY + + + +R + +
Sbjct: 876 LSPSHLTEDRQGRWKEE-DRKPERKES------SRRYEEQELKEKVSSVDKQREQTEILE 928
Query: 305 PQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS 364
+ G + D+ET+ R DE + + + + K+ + G
Sbjct: 929 SSRMRAQDIIG----HHQSEDRETSD------RAHDENKKKAKIQKKPIKKKKED-DVGI 977
Query: 365 EKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 424
E+G E ED + FS K+ K+K + + ++ D ++D+ + +
Sbjct: 978 ERGNIETTSEDGQV---FSPKKGQKKKSIEKKRKKSKGDSD--------ISDEEAAQQSK 1026
Query: 425 SHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHK-EEDKNS 483
R + K ++ N ++ G E+ + K ++T + D+ + E +++
Sbjct: 1027 KKRGPRTPPITTKEELVEMCNGKN-GILED-SQKKEDTAFSDWSDEDVPDRTEVTEAEHT 1084
Query: 484 ERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFR----------EESPLRI 533
T T SP L L PP+ +T S + I
Sbjct: 1085 ATATTPGSTPSP-------LSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITI 1137
Query: 534 KMIAS------------DSHR------------PEVKLKMAP--VPLDD----------S 557
A+ DSHR P V ++ A P+D S
Sbjct: 1138 STSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRS 1197
Query: 558 NRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQ 617
NR + + R ++ H +Q R H K+ S S + +K
Sbjct: 1198 NRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRG 1257
Query: 618 YFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEEN 677
+ + T S+R S HS+R+ SPE R++ + RL +R E+
Sbjct: 1258 --EPSRSTSSDRQDS-----RSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY---EH 1307
Query: 678 QKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDD 737
+ ++ R D+ D D K+ + R + R + ++ D + + D
Sbjct: 1308 DRERERERRDTRQREWDRD-ADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDS 1366
Query: 738 SKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEE 774
+ R++D + SS S + E + ER+ E
Sbjct: 1367 VERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLE 1403
Score = 44.3 bits (103), Expect = 5e-04
Identities = 59/212 (27%), Positives = 80/212 (37%), Gaps = 50/212 (23%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
R +SRSHSSR +SS S + HSR + SR R R R Y D R+ R
Sbjct: 1267 RQDSRSHSSR-----RSSPESDRQVHSRSGSFDSRDRLQERDR-----YEHDRERE-RER 1315
Query: 63 RAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRS-PKRRSVSSQ 121
R R+ R + W R R R R R R KRR + +
Sbjct: 1316 RDTRQREWDRDADKD-----------------WPRNRDRDRLRERERERERDKRRDLDRE 1358
Query: 122 RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEL--QEESPLKS 179
R R S R R + S SQ + K+ E +L + E L+S
Sbjct: 1359 RERLISDSVERDRDRDRDRTFES--------------SQIESVKRCEAKLEGEHERDLES 1404
Query: 180 KSQEE---PKDTFEHD--SSESIDEFNKSSAT 206
S++ K+ + D S + +E NKS T
Sbjct: 1405 TSRDSLALDKERMDKDLGSVQGFEETNKSERT 1436
Score = 40.4 bits (93), Expect = 0.007
Identities = 49/197 (24%), Positives = 76/197 (38%), Gaps = 24/197 (12%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 63
S+ + H +R + H RK + RS + +RS +R ++ R N+
Sbjct: 1156 SHRKCHRTRVEKVETPHVTIEDAQH-RKPMDQKRSSSLGSNRS-NRSHTSGRLRSPSNDS 1213
Query: 64 AMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRS 123
A R GR R + G SR + +S + +R+S Q
Sbjct: 1214 AHRSGDDQSGRKRVLHSG------------------SRDREKTKSLEITGERKSRIDQLK 1255
Query: 124 RSRSRRSYRSSRSP-RSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQ 182
R RS S R RS SSR SSP S V R GS + + + E + E + +
Sbjct: 1256 RGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHD---RERE 1312
Query: 183 EEPKDTFEHDSSESIDE 199
E +DT + + D+
Sbjct: 1313 RERRDTRQREWDRDADK 1329
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 80.9 bits (198), Expect = 5e-15
Identities = 74/203 (36%), Positives = 99/203 (48%), Gaps = 11/203 (5%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRS-RSRTYSRSRSRDRMYSRDYRRDYR- 60
RS SRS R SRS+S SR R RS S++KR RS + R+ SR R R R SRD R+ R
Sbjct: 1862 RSRSRSRRRRRSSRSRSKSRGR-RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRA 1920
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRS---RSRSPKRR 116
+R R R GR P R SR+P RR R+ RSR+P RR
Sbjct: 1921 RSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP---SRRSRTPSRRSRTPSRRSRTPSRR 1977
Query: 117 S-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEES 175
S S+RSR+ SRRS SR RS S +S SPV RR + + + ++ +
Sbjct: 1978 SRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKR 2037
Query: 176 PLKSKSQEEPKDTFEHDSSESID 198
S+ PK + D ++ ++
Sbjct: 2038 SRSSERGRSPKRLTDLDKAQLLE 2060
Score = 72.0 bits (175), Expect = 2e-12
Identities = 71/204 (34%), Positives = 94/204 (46%), Gaps = 29/204 (14%)
Query: 3 RSNSRSHSSR---SKSRSQSSSRS-RSRSHSRKKRYRSRSRTY---SRSRSRD---RMYS 52
RS S H SR S+SRS++ RS +S+SH + R RSRSR SRSRS+ R S
Sbjct: 1828 RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVS 1887
Query: 53 RDYR----------RDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRS 102
++ R R+ + R+ R R R R H RR SRS
Sbjct: 1888 KEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-----RRRRSRS 1942
Query: 103 PRRGRSRSRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQE 161
R RS S SP RRS S+RSR+ SRRS SR R+ S RS +P +S RR
Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002
Query: 162 KQTKKAEGELQEESPLKSKSQEEP 185
++ + SP++ + P
Sbjct: 2003 SVVRRRSFSI---SPVRLRRSRTP 2023
Score = 67.0 bits (162), Expect = 7e-11
Identities = 64/199 (32%), Positives = 91/199 (45%), Gaps = 29/199 (14%)
Query: 3 RSNSRSHSSRSKSRSQSSSR-------SRSRSHSRKKRYRS---RSRTYSRSRSRDRMYS 52
+ R S RS+S+ SS S SRS +RK+ +S RS+T SRSRSR R S
Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS 1873
Query: 53 RDYRRDYRNNRAM---RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 109
R R R++ +R + R + + R + V R SR+P R RSR
Sbjct: 1874 SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--RARSRTPSR-RSR 1930
Query: 110 SRSPKRRSVS-------------SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 156
S +P RR S S+RSR+ SRRS SR R+ S RS +P +S R
Sbjct: 1931 SHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990
Query: 157 RGSQEKQTKKAEGELQEES 175
R + +++ ++ S
Sbjct: 1991 RSRTPSRRRRSRSVVRRRS 2009
Score = 54.7 bits (130), Expect = 4e-07
Identities = 63/222 (28%), Positives = 89/222 (40%), Gaps = 14/222 (6%)
Query: 98 RHSRSPRRGRSRSRSPKRRSVSSQ-RSRSRSRRSYRSSRS-PRSSSSRSSSPYSKSPVSK 155
R S R R+R RS K +S SQ RSRSRSRR RSSRS +S RS S + K
Sbjct: 1837 RKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPK 1896
Query: 156 RRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLS 215
R ++ +K ++++S+ + + H S + I P
Sbjct: 1897 HRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRR 1956
Query: 216 AYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSV 275
+ S RS +PS + PS+ S T TPS+ S + S R V
Sbjct: 1957 SRTPSRRS-RTPSRRSRTPSRRS--------RTPSRRSRTPSRRSRT--PSRRRRSRSVV 2005
Query: 276 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 317
S SP + P RR +++ + R RGRS
Sbjct: 2006 RRRSFSISPVRLRR-SRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Score = 50.4 bits (119), Expect = 7e-06
Identities = 53/165 (32%), Positives = 71/165 (43%), Gaps = 42/165 (25%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTY-SRSRSRDRMY-SRDYRRDYR 60
++ +R + K R SS RSRS+ S+ ++SR RT SRSR+R R S+ +R R
Sbjct: 1805 KNKNRDKGEKEKKRD-SSLRSRSK-RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR 1862
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGR--------SRSRS 112
+ RR RR SRS + R R RS
Sbjct: 1863 SRSRSRR----------------------------RRRSSRSRSKSRGRRSVSKEKRKRS 1894
Query: 113 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRR 157
PK RS S +R R RS S R +R + SR+ S S+S RR
Sbjct: 1895 PKHRSKSRERKRKRS--SSRDNRKTVRARSRTPSRRSRSHTPSRR 1937
Score = 41.2 bits (95), Expect = 0.004
Identities = 56/248 (22%), Positives = 91/248 (36%), Gaps = 6/248 (2%)
Query: 96 NRRHSRSPRRGRSRSRSPKRRSVSSQ-RSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-PV 153
NR ++ S RS +RS SS+ +SR R+ S RS RSS S+S ++S
Sbjct: 1808 NRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSES-RSRARKRSSKSKSHRSQTRSRSR 1866
Query: 154 SKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPG 213
S+RR + K+ G + +S + + E S N+ + P
Sbjct: 1867 SRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPS 1926
Query: 214 LSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSG 273
+ +P + +S S S + T TPS+ S +
Sbjct: 1927 RRSRSHTPSRRRRSRSVGR--RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1984
Query: 274 SVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQ-ETAKTG 332
S +PS+ + RRS + + R R R S P + +++ G
Sbjct: 1985 SRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERG 2044
Query: 333 KFLKRFTD 340
+ KR TD
Sbjct: 2045 RSPKRLTD 2052
Score = 40.8 bits (94), Expect = 0.005
Identities = 73/314 (23%), Positives = 115/314 (36%), Gaps = 39/314 (12%)
Query: 466 VERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTF 525
+E P KD H + N+ V K+T+ P VK L L +E S
Sbjct: 1655 IEGPLPAKDIHLDLPSNNN--LVSKDTEEPLPVKES--------DQTLAALLSPKESSGG 1704
Query: 526 REESPLRIKMIASDSHRP-------EVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 578
+E P K DS E L + P+ D R SL + + L V
Sbjct: 1705 EKEVPPPPKETLPDSGFSANIEDINEADL-VRPLLPKDMERLTSL-RAGIEGPLLASDVG 1762
Query: 579 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSL-VHHVKEQYFKSAAMTLSERFTSYQKAT 637
+++ S +AS+S+SE + + + V E+ K+ E+ +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 638 EEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDH 697
S R KS E R S S R +R K ++ + + R S
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSR------ARKRSSKSKSHRSQTRSRSRS--------R 1868
Query: 698 RRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPS 757
RR+ S+ R S+G R S K++++PK ++S + K KR + A
Sbjct: 1869 RRRRSSRSRSKSRG-RRSVSKEKRKRSPK----HRSKSRERKRKRSSSRDNRKTVRARSR 1923
Query: 758 SPSSREEKESKKER 771
+PS R + R
Sbjct: 1924 TPSRRSRSHTPSRR 1937
Score = 36.2 bits (82), Expect = 0.14
Identities = 26/104 (25%), Positives = 42/104 (40%), Gaps = 4/104 (3%)
Query: 674 KEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKS 733
K+ ++K K D + D + RSK S+ R S + + K + KS
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856
Query: 734 YKDD----SKHKREQDHSLSSSSSASPSSPSSREEKESKKEREE 773
++ S+ +R + S S S S S S + K S K R +
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSK 1900
Score = 33.1 bits (74), Expect = 1.1
Identities = 19/85 (22%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Query: 673 FKEENQKGDKKLRCDSA--DLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKE 730
+K + ++G +K RC S D +I ++ ++ K+ + K ++ +K ++ P++ +
Sbjct: 79 YKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES 138
Query: 731 YKSYKDDSKHKREQDHSLSSSSSAS 755
DD E D L S S
Sbjct: 139 KTKSHDDGNIDLESDSFLKFDSEPS 163
Score = 33.1 bits (74), Expect = 1.1
Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)
Query: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEE 184
SR R P S K +K++ ++++ KK + + EES K+KS ++
Sbjct: 87 SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQ-PEESESKTKSHDD 145
Query: 185 PKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAP 244
E DS D ++ SA ++ A+ S + SP+ + PP S S+
Sbjct: 146 GNIDLESDSFLKFD--SEPSAVALEL--PTRAFGPS-ETNESPAVVLEPPVVSMEVSEPH 200
Query: 245 MLSTVHSAKNT 255
+L T+ A T
Sbjct: 201 ILETLKPATKT 211
Score = 31.6 bits (70), Expect = 3.3
Identities = 52/206 (25%), Positives = 73/206 (35%), Gaps = 24/206 (11%)
Query: 118 VSSQRSRSRSRRSYRSSRSPRSSSSRSS--SPYSKSPVSKRRGSQEKQTKKAEGELQEES 175
V RS + S R+ SSS + K + + + K K E E + +S
Sbjct: 1761 VGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDS 1820
Query: 176 PLKSKSQEEPKDTFEHDS----SESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIA 231
L+S+S+ EH S SES K S+ S S S S
Sbjct: 1821 SLRSRSKRSKSS--EHKSRKRTSESRSRARKRSSK--------SKSHRSQTRSRSRSRRR 1870
Query: 232 TPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIH 291
S+S S S + K +P S S + +RS SSR +
Sbjct: 1871 RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRS--------SSRDNRKTVRARS 1922
Query: 292 HIPSRRSPAKTIAPQNAPRDESRGRS 317
PSRRS + T + + R R RS
Sbjct: 1923 RTPSRRSRSHTPSRRRRSRSVGRRRS 1948
Score = 30.4 bits (67), Expect = 7.4
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 11/130 (8%)
Query: 462 TGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAR- 520
T + + S KHK + K ++ KK + PE+ +S K K D + L + +
Sbjct: 100 TDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES-KTKSHDDGNIDLESDSFLKF 158
Query: 521 --EKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSN-------RPASLTKDRLLAS 571
E S E P R + + P V L+ V ++ S +PA+ T + + S
Sbjct: 159 DSEPSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVS 218
Query: 572 TLVHSVKKEQ 581
T V S + EQ
Sbjct: 219 TSVISEQSEQ 228
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 80.9 bits (198), Expect = 5e-15
Identities = 74/203 (36%), Positives = 99/203 (48%), Gaps = 11/203 (5%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRS-RSRTYSRSRSRDRMYSRDYRRDYR- 60
RS SRS R SRS+S SR R RS S++KR RS + R+ SR R R R SRD R+ R
Sbjct: 1862 RSRSRSRRRRRSSRSRSKSRGR-RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRA 1920
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRS---RSRSPKRR 116
+R R R GR P R SR+P RR R+ RSR+P RR
Sbjct: 1921 RSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISP---SRRSRTPSRRSRTPSRRSRTPSRR 1977
Query: 117 S-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEES 175
S S+RSR+ SRRS SR RS S +S SPV RR + + + ++ +
Sbjct: 1978 SRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKR 2037
Query: 176 PLKSKSQEEPKDTFEHDSSESID 198
S+ PK + D ++ ++
Sbjct: 2038 SRSSERGRSPKRLTDLDKAQLLE 2060
Score = 72.0 bits (175), Expect = 2e-12
Identities = 71/204 (34%), Positives = 94/204 (46%), Gaps = 29/204 (14%)
Query: 3 RSNSRSHSSR---SKSRSQSSSRS-RSRSHSRKKRYRSRSRTY---SRSRSRD---RMYS 52
RS S H SR S+SRS++ RS +S+SH + R RSRSR SRSRS+ R S
Sbjct: 1828 RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVS 1887
Query: 53 RDYR----------RDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRS 102
++ R R+ + R+ R R R R H RR SRS
Sbjct: 1888 KEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-----RRRRSRS 1942
Query: 103 PRRGRSRSRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQE 161
R RS S SP RRS S+RSR+ SRRS SR R+ S RS +P +S RR
Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002
Query: 162 KQTKKAEGELQEESPLKSKSQEEP 185
++ + SP++ + P
Sbjct: 2003 SVVRRRSFSI---SPVRLRRSRTP 2023
Score = 67.0 bits (162), Expect = 7e-11
Identities = 64/199 (32%), Positives = 91/199 (45%), Gaps = 29/199 (14%)
Query: 3 RSNSRSHSSRSKSRSQSSSR-------SRSRSHSRKKRYRS---RSRTYSRSRSRDRMYS 52
+ R S RS+S+ SS S SRS +RK+ +S RS+T SRSRSR R S
Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS 1873
Query: 53 RDYRRDYRNNRAM---RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 109
R R R++ +R + R + + R + V R SR+P R RSR
Sbjct: 1874 SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--RARSRTPSR-RSR 1930
Query: 110 SRSPKRRSVS-------------SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 156
S +P RR S S+RSR+ SRRS SR R+ S RS +P +S R
Sbjct: 1931 SHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990
Query: 157 RGSQEKQTKKAEGELQEES 175
R + +++ ++ S
Sbjct: 1991 RSRTPSRRRRSRSVVRRRS 2009
Score = 54.7 bits (130), Expect = 4e-07
Identities = 63/222 (28%), Positives = 89/222 (40%), Gaps = 14/222 (6%)
Query: 98 RHSRSPRRGRSRSRSPKRRSVSSQ-RSRSRSRRSYRSSRS-PRSSSSRSSSPYSKSPVSK 155
R S R R+R RS K +S SQ RSRSRSRR RSSRS +S RS S + K
Sbjct: 1837 RKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPK 1896
Query: 156 RRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLS 215
R ++ +K ++++S+ + + H S + I P
Sbjct: 1897 HRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRR 1956
Query: 216 AYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSV 275
+ S RS +PS + PS+ S T TPS+ S + S R V
Sbjct: 1957 SRTPSRRS-RTPSRRSRTPSRRS--------RTPSRRSRTPSRRSRT--PSRRRRSRSVV 2005
Query: 276 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 317
S SP + P RR +++ + R RGRS
Sbjct: 2006 RRRSFSISPVRLRR-SRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Score = 50.4 bits (119), Expect = 7e-06
Identities = 53/165 (32%), Positives = 71/165 (43%), Gaps = 42/165 (25%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTY-SRSRSRDRMY-SRDYRRDYR 60
++ +R + K R SS RSRS+ S+ ++SR RT SRSR+R R S+ +R R
Sbjct: 1805 KNKNRDKGEKEKKRD-SSLRSRSK-RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR 1862
Query: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGR--------SRSRS 112
+ RR RR SRS + R R RS
Sbjct: 1863 SRSRSRR----------------------------RRRSSRSRSKSRGRRSVSKEKRKRS 1894
Query: 113 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRR 157
PK RS S +R R RS S R +R + SR+ S S+S RR
Sbjct: 1895 PKHRSKSRERKRKRS--SSRDNRKTVRARSRTPSRRSRSHTPSRR 1937
Score = 41.2 bits (95), Expect = 0.004
Identities = 56/248 (22%), Positives = 91/248 (36%), Gaps = 6/248 (2%)
Query: 96 NRRHSRSPRRGRSRSRSPKRRSVSSQ-RSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-PV 153
NR ++ S RS +RS SS+ +SR R+ S RS RSS S+S ++S
Sbjct: 1808 NRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSES-RSRARKRSSKSKSHRSQTRSRSR 1866
Query: 154 SKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPG 213
S+RR + K+ G + +S + + E S N+ + P
Sbjct: 1867 SRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPS 1926
Query: 214 LSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSG 273
+ +P + +S S S + T TPS+ S +
Sbjct: 1927 RRSRSHTPSRRRRSRSVGR--RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1984
Query: 274 SVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQ-ETAKTG 332
S +PS+ + RRS + + R R R S P + +++ G
Sbjct: 1985 SRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERG 2044
Query: 333 KFLKRFTD 340
+ KR TD
Sbjct: 2045 RSPKRLTD 2052
Score = 40.8 bits (94), Expect = 0.005
Identities = 73/314 (23%), Positives = 115/314 (36%), Gaps = 39/314 (12%)
Query: 466 VERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTF 525
+E P KD H + N+ V K+T+ P VK L L +E S
Sbjct: 1655 IEGPLPAKDIHLDLPSNNN--LVSKDTEEPLPVKES--------DQTLAALLSPKESSGG 1704
Query: 526 REESPLRIKMIASDSHRP-------EVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 578
+E P K DS E L + P+ D R SL + + L V
Sbjct: 1705 EKEVPPPPKETLPDSGFSANIEDINEADL-VRPLLPKDMERLTSL-RAGIEGPLLASDVG 1762
Query: 579 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSL-VHHVKEQYFKSAAMTLSERFTSYQKAT 637
+++ S +AS+S+SE + + + V E+ K+ E+ +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 638 EEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDH 697
S R KS E R S S R +R K ++ + + R S
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSR------ARKRSSKSKSHRSQTRSRSRS--------R 1868
Query: 698 RRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPS 757
RR+ S+ R S+G R S K++++PK ++S + K KR + A
Sbjct: 1869 RRRRSSRSRSKSRG-RRSVSKEKRKRSPK----HRSKSRERKRKRSSSRDNRKTVRARSR 1923
Query: 758 SPSSREEKESKKER 771
+PS R + R
Sbjct: 1924 TPSRRSRSHTPSRR 1937
Score = 36.2 bits (82), Expect = 0.14
Identities = 26/104 (25%), Positives = 42/104 (40%), Gaps = 4/104 (3%)
Query: 674 KEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKS 733
K+ ++K K D + D + RSK S+ R S + + K + KS
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856
Query: 734 YKDD----SKHKREQDHSLSSSSSASPSSPSSREEKESKKEREE 773
++ S+ +R + S S S S S S + K S K R +
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSK 1900
Score = 33.1 bits (74), Expect = 1.1
Identities = 19/85 (22%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Query: 673 FKEENQKGDKKLRCDSA--DLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKE 730
+K + ++G +K RC S D +I ++ ++ K+ + K ++ +K ++ P++ +
Sbjct: 79 YKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES 138
Query: 731 YKSYKDDSKHKREQDHSLSSSSSAS 755
DD E D L S S
Sbjct: 139 KTKSHDDGNIDLESDSFLKFDSEPS 163
Score = 33.1 bits (74), Expect = 1.1
Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 6/131 (4%)
Query: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEE 184
SR R P S K +K++ ++++ KK + + EES K+KS ++
Sbjct: 87 SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQ-PEESESKTKSHDD 145
Query: 185 PKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAP 244
E DS D ++ SA ++ A+ S + SP+ + PP S S+
Sbjct: 146 GNIDLESDSFLKFD--SEPSAVALEL--PTRAFGPS-ETNESPAVVLEPPVVSMEVSEPH 200
Query: 245 MLSTVHSAKNT 255
+L T+ A T
Sbjct: 201 ILETLKPATKT 211
Score = 31.6 bits (70), Expect = 3.3
Identities = 52/206 (25%), Positives = 73/206 (35%), Gaps = 24/206 (11%)
Query: 118 VSSQRSRSRSRRSYRSSRSPRSSSSRSS--SPYSKSPVSKRRGSQEKQTKKAEGELQEES 175
V RS + S R+ SSS + K + + + K K E E + +S
Sbjct: 1761 VGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDS 1820
Query: 176 PLKSKSQEEPKDTFEHDS----SESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIA 231
L+S+S+ EH S SES K S+ S S S S
Sbjct: 1821 SLRSRSKRSKSS--EHKSRKRTSESRSRARKRSSK--------SKSHRSQTRSRSRSRRR 1870
Query: 232 TPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIH 291
S+S S S + K +P S S + +RS SSR +
Sbjct: 1871 RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRS--------SSRDNRKTVRARS 1922
Query: 292 HIPSRRSPAKTIAPQNAPRDESRGRS 317
PSRRS + T + + R R RS
Sbjct: 1923 RTPSRRSRSHTPSRRRRSRSVGRRRS 1948
Score = 30.4 bits (67), Expect = 7.4
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 11/130 (8%)
Query: 462 TGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAR- 520
T + + S KHK + K ++ KK + PE+ +S K K D + L + +
Sbjct: 100 TDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES-KTKSHDDGNIDLESDSFLKF 158
Query: 521 --EKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSN-------RPASLTKDRLLAS 571
E S E P R + + P V L+ V ++ S +PA+ T + + S
Sbjct: 159 DSEPSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVS 218
Query: 572 TLVHSVKKEQ 581
T V S + EQ
Sbjct: 219 TSVISEQSEQ 228
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 80.9 bits (198), Expect = 5e-15
Identities = 176/836 (21%), Positives = 306/836 (36%), Gaps = 130/836 (15%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA 64
NS S S S SS S RS SR R RS SR+Y+RSRS +SR
Sbjct: 670 NSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRS---------- 719
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
R R R Y Y + + R+ RR RS S K+ SVS ++
Sbjct: 720 --RSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRS---SGKKNSVSHKKHS 774
Query: 125 SRSRRSY---------RSSRSPRSSSSRSSSPYSK-SPVSKRRGSQEKQTKKAEGELQEE 174
S S ++ RSS + S SRSS YS S S + +Q Q K+ +G+++
Sbjct: 775 SSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERT 834
Query: 175 SPLKSKSQEEPKDTFEHDSSESIDEFNKSSAT--------------CGDIW--PGLSAYD 218
+ K++ E K E + S K + + G W S D
Sbjct: 835 HNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERD 894
Query: 219 XSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNG 278
+ S + P + ++ +S +H K P+ S + P+ +G+
Sbjct: 895 VTKNSKNDSHPSSDKEEGEATSDSESEVSEIH-IKVKPTTKSSTNTSLPDDNGAWKSSKQ 953
Query: 279 SSRYSPSQNSPIHHIPSRRSPAKTI--APQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336
+ S S+ S + +R P K + +N R+ ++ +E K K K
Sbjct: 954 RTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTK---------KVKEKLKGKKDKK 1004
Query: 337 RFTDEESRVF----LLDRGNTRDKEASKEKGSEKGRAEGEWEDQEAL-DYFSDKESGKQK 391
+ + F L+ G ++E ++ +++ + + E+ E + D E ++
Sbjct: 1005 HKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEE 1064
Query: 392 FNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGF 451
+ D + D QF K D K + + NTEE
Sbjct: 1065 DLSGKHDTVTVSSDLDQFTK----DDSKLSISPTALNTEENVACL--------------- 1105
Query: 452 REEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSP 511
+N +H E P+ +D + +D N E T + SP +V+ + SP
Sbjct: 1106 ---QNIQHVEESV----PNGVEDVLQTDD-NMEICT--PDRSSPAKVE--------ETSP 1147
Query: 512 PLHKNLDARE-----KSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPA----- 561
+ LD + K E P + +++ +S E K+ + V DS+ +
Sbjct: 1148 LGNARLDTPDINIVLKQDMATEHP-QAEVVKQESSMSESKV-LGEVGKQDSSSASLASAG 1205
Query: 562 -SLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 620
S K + + ++ + K+ + ++ P A +TS + +++ V +K Q
Sbjct: 1206 ESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNA--ATSSAVEVKVLTTVPEMKPQ--- 1260
Query: 621 SAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKG 680
+ + + + + +K+ ++RR S+ + T ++ + ++
Sbjct: 1261 --GLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSR 1318
Query: 681 DK-----KLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYK 735
K + R S H R S R S SRG + +T Y+SYK
Sbjct: 1319 SKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYK 1378
Query: 736 DDSKHKREQDHSLSSSSSASPSSPS------SREEKESKKEREEEFKTHHEMKEYS 785
R S S SSS P S S S + + R + ++H + Y+
Sbjct: 1379 S----HRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYN 1430
Score = 73.2 bits (178), Expect = 1e-12
Identities = 66/165 (40%), Positives = 80/165 (48%), Gaps = 29/165 (17%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 63
S+ ++ S S+S+S SRSRS+S + K R+R+RS +YS SRSR R + YR
Sbjct: 1298 SDEQTPSRDDDSQSRSPSRSRSKSET-KSRHRTRSVSYSHSRSRSRSSTSSYRS------ 1350
Query: 64 AMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRS------ 117
R Y R R RG+Y G R YR + R S S R RS S P RS
Sbjct: 1351 ---RSYS-RSRSRGWYSRGRTRSRSSSYRSYKSHRTS-SRSRSRSSSYDPHSRSRSYTYD 1405
Query: 118 --VSSQRSRSRSRRS---------YRSSRSPRSSSSRSSSPYSKS 151
S RSRSRS+RS R SRS RS S S S S S
Sbjct: 1406 SYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYS 1450
Score = 65.1 bits (157), Expect = 3e-10
Identities = 58/143 (40%), Positives = 68/143 (47%), Gaps = 11/143 (7%)
Query: 3 RSNSRSHSSRSKSRSQSSS-RSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRN 61
RS S SHS RS+SRS +SS RSRS S SR + + SR RT SRS S R Y+ +
Sbjct: 1330 RSVSYSHS-RSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSS-----YRSYKSHRTS 1383
Query: 62 NRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 121
+R+ R Y R Y R R R RS R RS + + RS S
Sbjct: 1384 SRSRSRSSSYDPHSRSRSYTYDSYYSRSRSR----SRSQRSDSYHRGRSYNRRSRSCRSY 1439
Query: 122 RSRSRSRRSYRSSRSPRSSSSRS 144
S S S RSY RSP SS S
Sbjct: 1440 GSDSESDRSYSHHRSPSESSRYS 1462
Score = 58.5 bits (140), Expect = 3e-08
Identities = 153/707 (21%), Positives = 259/707 (36%), Gaps = 101/707 (14%)
Query: 123 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESP-----L 177
S S SS S SS S S+ KRR ++ K+ + E P +
Sbjct: 195 SEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAM 254
Query: 178 KSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQS 237
K E DT E S +S + K +I P R P+ T +
Sbjct: 255 NPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRD----MPVVTAEPEP 310
Query: 238 SSCSDAPMLSTVHSAKNTPSQHSHSIQ-------HSPERSGSGSVG--NGSSRYSPSQNS 288
AP++S K + S+ I+ H+P RS S S + SS P
Sbjct: 311 KIPDVAPIVS---DQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKE 367
Query: 289 PIHHIPSRRSPA--------KTIAPQNAPRDE----SRGRS-SFYPDGGDQETAK-TGKF 334
+ + + R P+ K P ++ DE R RS S+ D TA+ +G
Sbjct: 368 EMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHH 427
Query: 335 LKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFND 394
KR +E +V +G + K + K ++K R + SD ES K
Sbjct: 428 KKR--RKEKKVKHKKKGK-KQKHCRRHKQTKKRR----------ILIPSDIESSKSSTRR 474
Query: 395 SEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTE-EEGLKYKSKVSLKGNRESDGFRE 453
+ E R R S L+ S S + + + L + S+ S + S +
Sbjct: 475 MKSSCDRE----RSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSY-- 528
Query: 454 EKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPL 513
+ T S ++ K + K+ R K+ ++SP + S+ L
Sbjct: 529 SRGSSRSRTASKSSSHSRSRSKSRSSSKSGHR---KRASKSPRKTASQ-----------L 574
Query: 514 HKNLDAREKSTFREESPLRIKMIASDS--HRPEVKLKMAPVPLDDSNRPASLTKDRLLAS 571
+N + + PLR M +++ +P V + +PL DS P+ +
Sbjct: 575 SENKPVKTE-------PLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQ---K 624
Query: 572 TLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFT 631
S ++ QE ++ H+ LP S + + + S +H +E+ +S T ++
Sbjct: 625 PWKPSYERIQEMKAKTTHL-LPIQSTYSLANIKETGSSSSYHKREKNSESDQST----YS 679
Query: 632 SYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSA-- 689
Y + E S R +S R S S R + + R ++ + D +
Sbjct: 680 KYSDRSSESSPRSRSRSSRSR-SYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQC 738
Query: 690 -------DLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKR 742
+ D R K R + G + S EKT + +Y +D S R
Sbjct: 739 SRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTL--HSKYVKGRDRSSCVR 796
Query: 743 EQDHSLSSSSSASPSSPSSREEKESKKEREEE---FKTHHEMKEYSG 786
+ S SS +S S SS + +S +E+E++ +TH++ ++ G
Sbjct: 797 KYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRG 843
Score = 57.4 bits (137), Expect = 6e-08
Identities = 141/611 (23%), Positives = 212/611 (34%), Gaps = 128/611 (20%)
Query: 2 GRSNSRSHSS-RSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
GR R H+ RS+S S+S S + K R R Y R S ++ D D
Sbjct: 335 GRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAY-RPPSGEKWSKGDKLSDPC 393
Query: 61 NNRAMRRPYGYRGRG---RGYYQGGGGRYHRG----------------GYRPVWNRRHSR 101
++R R R R GYY H G G + RRH +
Sbjct: 394 SSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQ 453
Query: 102 -----------------SPRRGRS---RSRSPKRRSVSSQRSRSR--------------- 126
S RR +S R RS + S+SS S R
Sbjct: 454 TKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTH 513
Query: 127 -SRRSYRS---SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQ 182
SR SYRS S+S SSRS + S S+ R +K + +SP K+ SQ
Sbjct: 514 SSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQ 573
Query: 183 ---EEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPS---- 235
+P T ++ + +E + P + D P S P PS
Sbjct: 574 LSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERI 633
Query: 236 ---QSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYS--PSQNSPI 290
++ + P+ ST +S N S S H E++ S S + S+YS S++SP
Sbjct: 634 QEMKAKTTHLLPIQST-YSLANIKETGSSSSYHKREKN-SESDQSTYSKYSDRSSESSPR 691
Query: 291 HHIPSRRSP------------AKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRF 338
S RS A + + +P S R+ + + +++ +
Sbjct: 692 SRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKY---SDHSQCSRSSSYTSIS 748
Query: 339 TDEESRVFLLDRGNTRDKEASKEKGSE-----------KGRAEGEW-----EDQEALDYF 382
+D+ R R + + S +K S KGR E + +LDY
Sbjct: 749 SDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYS 808
Query: 383 SDKESGKQKFNDSEGD-----DTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGL--- 434
SD E + S + E T + ++ + + + S + T +E L
Sbjct: 809 SDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDH 868
Query: 435 -------KYK----SKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNS 483
K K SK + N E D + KND H + E T D E + +
Sbjct: 869 LRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSD--KEEGEATSD--SESEVSE 924
Query: 484 ERITVKKETQS 494
I VK T+S
Sbjct: 925 IHIKVKPTTKS 935
Score = 57.0 bits (136), Expect = 7e-08
Identities = 164/820 (20%), Positives = 287/820 (35%), Gaps = 134/820 (16%)
Query: 8 SHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRAMRR 67
+HS S S S SSS S S S S + RSR R + R R S+ R++ ++ R
Sbjct: 193 THSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKR--SKKRRKEASSSEEPRN 250
Query: 68 PYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRS 127
+H+ +P+ RS + ++RSV S S R
Sbjct: 251 ------------------------------KHAMNPKGHSERSDTNEKRSVDS--SAKRE 278
Query: 128 RRSYRSSRSPRSSSSR----------SSSPYSKSP-----VSKRRGSQEKQTKKAEGE-- 170
+ R P +R ++ P K P VS ++ S K +K +G
Sbjct: 279 KPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGT 338
Query: 171 LQEESPLKSKSQEEPKDTFEHDS----SESIDEFNKSSATCGDIW--------PGLSAYD 218
++ +P +S+S E D ++ E + G+ W P S +D
Sbjct: 339 IRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWD 398
Query: 219 XSPRSPHSPSPIATPPSQSSSCSDAPMLSTV-HSAKNTPSQHSHSIQHSPERSGSGSVGN 277
S S S S + SD LST HS + + ++H + G
Sbjct: 399 ERSLSQRSRSW-----SYNGYYSD---LSTARHSGHHKKRRKEKKVKHKKK----GKKQK 446
Query: 278 GSSRYSPSQNSPI---HHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKF 334
R+ ++ I I S +S + + SR S ++ +K+ K
Sbjct: 447 HCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKD 506
Query: 335 LKRFTDEESRVFL--------LDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKE 386
++ SR RG++R + ASK + R++ + + K
Sbjct: 507 VQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKS 566
Query: 387 SGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSL--KG 444
K SE + R ++ ++ N L S G
Sbjct: 567 PRKTASQLSENKPVKT----EPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPG 622
Query: 445 NRESDGFREEKNDKHKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLK 504
+ E + +T +++ ST + +E +S +++ +Q K
Sbjct: 623 QKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYS 682
Query: 505 DLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLT 564
D S P ++ +R +S R S R + +AS R S+R S
Sbjct: 683 DRSSESSPRSRSRSSRSRSYSR--SYTRSRSLASSHSRSR----------SPSSRSHSRN 730
Query: 565 K----DRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 620
K + S+ S+ + R+ +L + K S S +H S + +Y K
Sbjct: 731 KYSDHSQCSRSSSYTSISSDDGRRA---KRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVK 787
Query: 621 SAAMTLSERFTSYQKATEEHSTRQKSPEIHRR-IDISPSTLRKDTRLAGEERVFKEENQK 679
+R + +K +E S+ S + + + + S K+ + E K+E +
Sbjct: 788 GR-----DRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNR 842
Query: 680 GDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSK 739
G++K + + + H +K KE S+ RK Y K DS+
Sbjct: 843 GEEKSKSE-----RECPHSKKRTLKENLSDHLRNGSKPKRKN---------YAGSKWDSE 888
Query: 740 HKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHH 779
E+D + +S + + PS S +EE E+ + E E H
Sbjct: 889 SNSERDVTKNSKNDSHPS--SDKEEGEATSDSESEVSEIH 926
Score = 54.3 bits (129), Expect = 5e-07
Identities = 145/801 (18%), Positives = 274/801 (34%), Gaps = 93/801 (11%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA 64
+ R R R + RSRS S S + R R Y +
Sbjct: 329 SGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDK 388
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR-- 122
+ P R R Q + G Y + RHS ++ R + ++ Q+
Sbjct: 389 LSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHC 448
Query: 123 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQ 182
R + + R SS+SS+ KS + R S+ ++ SKS
Sbjct: 449 RRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRD----WSKSD 504
Query: 183 EEPKDTFEHDSSESI-DEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCS 241
++ + + H S +S + + S + G ++ S S S ++ S
Sbjct: 505 KDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRAS 564
Query: 242 DAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHI-----PSR 296
+P + ++N P ++ P R+ N + ++N P+ + PSR
Sbjct: 565 KSPRKTASQLSENKP------VKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSR 618
Query: 297 RSPA-KTIAPQNAPRDESRGRS-------SFYPDGGDQETAKTGKFLKRFTDEESRVFLL 348
P K P E + ++ S Y +ET + + KR + ES
Sbjct: 619 WKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTY 678
Query: 349 DRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQ 408
+ + R E+S S R+ S S + + + + R
Sbjct: 679 SKYSDRSSESSPRSRSRSSRSR------------SYSRSYTRSRSLASSHSRSRSPSSRS 726
Query: 409 FRKSVLADQGKSFATASHRN-TEEEGLKYKSKVSLKGNRESDGFREEKNDKHK--ETGYV 465
++ +D + ++S+ + + ++G + K ++ G + S ++ + K + YV
Sbjct: 727 HSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYV 786
Query: 466 VERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTF 525
R ++ + E ++S + E S + +S + K + + + + +EK+
Sbjct: 787 KGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEK---EKQGQMERTHNKQEKNRG 843
Query: 526 REESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLA-------STLVHSVK 578
E+S S+ P K + L D R S K + A S V
Sbjct: 844 EEKS-------KSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVT 896
Query: 579 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATE 638
K + S K + S SES + I H+K K T
Sbjct: 897 KNSKNDSHPSSDKEEGEATSDSESEVSEI-----HIK------------------VKPTT 933
Query: 639 EHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKG--DKKLRCDSADLRHDID 696
+ ST P+ + S+ ++ + E EN +G K +L+ +
Sbjct: 934 KSSTNTSLPDDN---GAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHT 990
Query: 697 HRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEY-------KSYKDDSKHKREQDHSLS 749
+ KE+ K + D K R + P ++ E K +SK K+ +++ +
Sbjct: 991 KKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNET 1050
Query: 750 SSSSASPSSPSSREEKESKKE 770
+ + SS E+ K +
Sbjct: 1051 IKDNILKTEKSSEEDLSGKHD 1071
Score = 37.7 bits (86), Expect = 0.047
Identities = 39/140 (27%), Positives = 51/140 (36%), Gaps = 12/140 (8%)
Query: 704 KERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSS-SASPSSPSSR 762
KE G S S ++++ + D Y Y D S + S SS S S S S SR
Sbjct: 656 KETGSS-----SSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSR 710
Query: 763 EEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGR 822
S H +YS + SR DDG +R + R +
Sbjct: 711 SLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDG-----RRAKRRLRSSGKK 765
Query: 823 GRFNFKK-SGSSPKWNHDKY 841
+ KK S SS K H KY
Sbjct: 766 NSVSHKKHSSSSEKTLHSKY 785
Score = 34.7 bits (78), Expect = 0.39
Identities = 42/182 (23%), Positives = 72/182 (39%), Gaps = 15/182 (8%)
Query: 687 DSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKT-------PKDYKEYKSYKDDSK 739
D + RH H+++ + K+ K ++ + R+ ++T P D + KS K
Sbjct: 417 DLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMK 476
Query: 740 HKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEY-SGFAGVSRPRGTFH 798
+++ S S SSS S S R+ +S K+ + TH Y S S RG+
Sbjct: 477 SSCDRERS-SRSSSLSSHHSSKRDWSKSDKDVQSSL-THSSRDSYRSKSHSQSYSRGS-- 532
Query: 799 DDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVEDE--EETMEN 856
R + R R + + K++ SP+ + + V+ E TM
Sbjct: 533 -SRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQ 591
Query: 857 NE 858
NE
Sbjct: 592 NE 593
Score = 34.7 bits (78), Expect = 0.39
Identities = 35/154 (22%), Positives = 51/154 (33%), Gaps = 10/154 (6%)
Query: 719 RKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKES----KKEREEE 774
R++EK K K+ K K +HK+ + + S S S+R K S + R
Sbjct: 430 RRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSS 489
Query: 775 FKTHHEMKEYSGFAGVSRPRGTFHDDRDD------GVDYWAKRGRGRGTFQRGRGRFNFK 828
+HH K + H RD Y R R + +
Sbjct: 490 LSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRS 549
Query: 829 KSGSSPKWNHDKYQGDGIVEDEEETMENNEEKKD 862
KS SS K H K + + EN K +
Sbjct: 550 KSRSSSKSGHRKRASKSPRKTASQLSENKPVKTE 583
Score = 33.5 bits (75), Expect = 0.88
Identities = 40/153 (26%), Positives = 58/153 (37%), Gaps = 17/153 (11%)
Query: 251 SAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPR 310
S + TPS+ S SP RS S S SR+ S H RS + ++ R
Sbjct: 1298 SDEQTPSRDDDSQSRSPSRSRSKS--ETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSR 1355
Query: 311 DESRG---------RSSFYPDGGDQETAKTGKFLKRFTD--EESRVFLLDRGNTRDKEAS 359
SRG RSS Y T+ + D SR + D +R + S
Sbjct: 1356 SRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRS 1415
Query: 360 KEKGSE---KGRAEGEWEDQEALDYFSDKESGK 389
+ + S+ +GR+ + Y SD ES +
Sbjct: 1416 RSQRSDSYHRGRSYNR-RSRSCRSYGSDSESDR 1447
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 80.5 bits (197), Expect = 6e-15
Identities = 169/736 (22%), Positives = 272/736 (36%), Gaps = 84/736 (11%)
Query: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPR-SSSSRSSSPYSKSPVSK 155
R SRSPRR +SRS SP+RRS +R R RS SRSPR + SRS SP +P K
Sbjct: 166 RERSRSPRRRKSRSPSPRRRSSPVRRERKRSH-----SRSPRHRTKSRSPSP---APEKK 217
Query: 156 RRGSQ--EKQTKKAEGELQEESPL-------KSKSQEEPKDTFEHDSSESIDEFNK---- 202
+ + E K E +QE + K + EPK+ +S+ E K
Sbjct: 218 EKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPR 277
Query: 203 --SSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHS 260
S + S PR H + P + S P + P
Sbjct: 278 SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR 337
Query: 261 HSIQHSP----ERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS--PAKT--IAPQNAPRDE 312
H SP RS + G+ SS S SP P R S P KT ++P +P
Sbjct: 338 HRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASP-PR 396
Query: 313 SRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGE 372
R R S P +T + + +SRV + G T K +K KG+EK +
Sbjct: 397 RRHRPS-PPATPPPKTRHSPTPQQSNRTRKSRV-SVSPGRTSGK-VTKHKGTEKRESPSP 453
Query: 373 WEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFAT------ASH 426
++ +E K + D ++ YR+ + +D G S ++ SH
Sbjct: 454 APKPRKVELSESEEDKGGKM--AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSH 511
Query: 427 RNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEE------D 480
E G + + S R + ++ + G PS + +
Sbjct: 512 VKNGEVGRRRRHSPS----RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPP 567
Query: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREES-PLRIKMIASD 539
+ T ++P + YSPP+ + R S P K AS
Sbjct: 568 RRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASP 627
Query: 540 SHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKST 599
S P+ ++ +P P R + +TK R + + H K RS + + PQ +K
Sbjct: 628 SPPPKRRVSHSPPP---KQRSSPVTKRRSPSLSSKHR-KGSSPSRSTRE-ARSPQPNKRH 682
Query: 600 SESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPST 659
S S + A + +R S +T ++PE ++I + S
Sbjct: 683 SPSPRPRAPQT--SSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE-PKKIKKAASP 739
Query: 660 LRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHR--------RKERSKERGDS-- 709
+ R R + KK + ++ +K +S S
Sbjct: 740 SPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP 799
Query: 710 -KGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPS------SR 762
+E G +K++K K +K+ K +K KHK+E+ + +++++ +P++ + ++
Sbjct: 800 RNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQ 859
Query: 763 EE----KESKKEREEE 774
EE E KKE E E
Sbjct: 860 EEPVAAPEPKKETESE 875
Score = 70.9 bits (172), Expect = 5e-12
Identities = 82/314 (26%), Positives = 122/314 (38%), Gaps = 41/314 (13%)
Query: 18 QSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRAMRRPYGYRGRGRG 77
+ S S+ K++ R RSR+ S+SRSR R S + R R +R+ R Y R R
Sbjct: 258 EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR--- 314
Query: 78 YYQGGGGRYHRGGYRPVWNRRHSRSPRRGRS-RSRSPKRR---SVSSQRSRSRSRRSYRS 133
SPRR S R R+P RR +RSRS RR RS
Sbjct: 315 -----------------------PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRS 351
Query: 134 SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDS 193
S S SSS SSS S+SP K +K SP + + + P T +
Sbjct: 352 SASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKT 411
Query: 194 --SESIDEFNKSSATCGDIWPGLSA----YDXSPRSPHSPSPIATPPSQSSSCSDAPMLS 247
S + + N++ + + PG ++ SPSP P S S+
Sbjct: 412 RHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGG 471
Query: 248 TVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRR--SPAKTIAP 305
+ +A + + + Q+ S SGS + + + RR SP+++ +P
Sbjct: 472 KMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASP 531
Query: 306 QNAPRDES---RGR 316
R + RGR
Sbjct: 532 SPRKRQKETSPRGR 545
Score = 56.2 bits (134), Expect = 1e-07
Identities = 101/387 (26%), Positives = 139/387 (35%), Gaps = 64/387 (16%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
R ++ SS S S S S RSH + R R +S SRS + +
Sbjct: 486 RRQNQQSSSDSGSSSSSEDERPKRSHVKNGEV-GRRRRHSPSRSASPSPRKRQKETSPRG 544
Query: 63 RAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 122
R R P R R P RR P R R+ S P+RRS S +R
Sbjct: 545 RRRRSPSPPPTRRRRSPSPAP---------PPRRRRTPTPPPRRRTPSPPPRRRSPSPRR 595
Query: 123 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQ 182
+R Y S P+ R++SP P KRR S K+ + P K +S
Sbjct: 596 YSPPIQRRYSPSPPPK---RRTASP---PPPPKRRASPSPPPKR---RVSHSPPPKQRSS 646
Query: 183 EEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSS--- 239
K SS+ + S +T A P HSPSP P SSS
Sbjct: 647 PVTKRRSPSLSSKHRKGSSPSRST-------REARSPQPNKRHSPSPRPRAPQTSSSPPP 699
Query: 240 ------------CSDAPMLSTVHSAKNTP---------SQHSHSIQH-SPERSGSGSVGN 277
S +P + TP S S++ S RS SGS
Sbjct: 700 VRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGS-PE 758
Query: 278 GSSRYSPSQNSPIH-HIPSRR-SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFL 335
+++ P+ SP+ PS SPA + +P S P DQE GK
Sbjct: 759 PAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTP-----SPSPPRNSDQEGG--GKKK 811
Query: 336 KRFTDEESRVFLLDRGNTRDKEASKEK 362
K+ D++ + D+ + + K+ KEK
Sbjct: 812 KKKKDKKHK---KDKKHKKHKKHKKEK 835
Score = 50.1 bits (118), Expect = 9e-06
Identities = 89/391 (22%), Positives = 132/391 (33%), Gaps = 51/391 (13%)
Query: 3 RSNSRSHSSRSK-SRSQSSSRSRSRSHSRKKRY----RSRSRTYSRS---RSRDRMYSRD 54
R SSR K RS+S R +SRS S ++R R R R++SRS R++ R S
Sbjct: 154 RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPA 213
Query: 55 YRRDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 114
+ + + P+ + + + K
Sbjct: 214 PEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEK 273
Query: 115 RRSVSSQRSRSRSRRSYRS-----SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169
R S RS+SRSR RS R S SRS SP + P +RR S ++T
Sbjct: 274 TRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP-RRRPSPRRRPSPRRRT----- 327
Query: 170 ELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSP 229
+ P S + +SSA+ LS S S S SP
Sbjct: 328 ----------PPRRMPPPPRHRRSRSPVRRRRRSSAS-------LSGSSSSSSSSRSRSP 370
Query: 230 IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSH----------SIQHSPERSGSGSVGNGS 279
PP ++SS P + S +P + H +HSP S
Sbjct: 371 PKKPPKRTSS---PPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSR 427
Query: 280 SRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFT 339
SP + S + + K +P AP+ S D G + A +R
Sbjct: 428 VSVSPGRTS--GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQY 485
Query: 340 DEESRVFLLDRGNTRDKEASKEKGSEKGRAE 370
+++ D G++ E + K S E
Sbjct: 486 RRQNQQSSSDSGSSSSSEDERPKRSHVKNGE 516
Score = 35.4 bits (80), Expect = 0.23
Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 12/171 (7%)
Query: 638 EEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGD----KKLRCDSADLRH 693
++ +Q+ E + + KD R E+ +E+ ++ +K R S R
Sbjct: 127 KKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRS 186
Query: 694 DIDHRRKERSKERGD---SKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSS 750
R ++RS R +K S K+EKTP+ + K+ S + +
Sbjct: 187 SPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILK 246
Query: 751 SSSASPSSPSSRE---EKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFH 798
P P +E EK SKKE+E+E KT + S +R R H
Sbjct: 247 VPKPEP-IPEPKEPSPEKNSKKEKEKE-KTRPRSRSRSKSRSRTRSRSPSH 295
Score = 31.6 bits (70), Expect = 3.3
Identities = 56/261 (21%), Positives = 86/261 (32%), Gaps = 28/261 (10%)
Query: 466 VERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTF 525
+++ KDK +E+K S R ++ ++SP + KS SP + RE+
Sbjct: 144 MKKQDEDKDKRDKEEKESSR-EKRERSRSPRRRKSRSP------SPRRRSSPVRRERKRS 196
Query: 526 REESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRS 585
SP S S PE K K +P ++ S ++ K E
Sbjct: 197 HSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEP---- 252
Query: 586 IFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQK 645
I P+ S + KS + T S R S+ + H +R +
Sbjct: 253 ----IPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRS-RSPSHTRPRRRHRSRSR 307
Query: 646 SPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKE 705
S RR SP R R+ + R + RR+ +
Sbjct: 308 SYSPRRR--PSPRRRPSPRRRTPPRRMPPPPRHRRS----------RSPVRRRRRSSASL 355
Query: 706 RGDSKGSRESRGSRKQEKTPK 726
G S S SR +K PK
Sbjct: 356 SGSSSSSSSSRSRSPPKKPPK 376
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 79.7 bits (195), Expect = 1e-14
Identities = 86/332 (25%), Positives = 132/332 (39%), Gaps = 50/332 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRN 61
G+SN R RS+S ++S SRS S+SHSR+KR +S+ R+ S +RSR R ++
Sbjct: 298 GKSNERK-GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ---------KD 347
Query: 62 NRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 121
R + P+ R + R R +R HSR R+ K R
Sbjct: 348 RRRSKSPHKKRSKSR-------------ERRKSRSRSHSRDKRKDTREKIKEKERVKEKD 394
Query: 122 RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKS 181
R + R R R R + K + +E++ +K + +++ K K
Sbjct: 395 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KEKE 452
Query: 182 QEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCS 241
Q++ K+ E D S+ IDE K P S Y+ S RS S S+SSS S
Sbjct: 453 QDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRS-YNASRRSRSSSRERRRRRSRSSSRS 508
Query: 242 DAPMLSTVHSAKNTPSQHSHS------------IQHSPERSGSGSVGNGSS--------- 280
+ + +PS S + I ER S S+ S+
Sbjct: 509 PRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 568
Query: 281 RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDE 312
+ S S H+ S +K + ++APR E
Sbjct: 569 KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600
Score = 55.5 bits (132), Expect = 2e-07
Identities = 74/355 (20%), Positives = 131/355 (36%), Gaps = 42/355 (11%)
Query: 225 HSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRY-- 282
HS + I PP + + + + + S S +I+ PE S G SR
Sbjct: 255 HSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIE--PESGKSNERKGGRSRSHT 312
Query: 283 -SPSQNSPIHHIPSRRSPAKTIA-----PQNAPRDESRGRSSFYPDGGDQETAKTG---- 332
S S++S H +RS +K + ++ +D R +S +E K+
Sbjct: 313 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 372
Query: 333 -----KFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKES 387
K + E+ RV DR R++E +EK E+G+ + +++E D+E
Sbjct: 373 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE-----KDREK 427
Query: 388 GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYK---------- 437
K+K D E + +E E R K D+ K + +E+ K K
Sbjct: 428 DKEK--DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYN 485
Query: 438 -SKVSLKGNRESDGFREEKNDKHKETGYVVER-----PSTTKDKHKEEDKNSERITVKKE 491
S+ S +RE R + + T ++R PS K++ + ER + +
Sbjct: 486 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER 545
Query: 492 TQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVK 546
+ K + D L KN + ++ +E + D P +
Sbjct: 546 RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600
Score = 51.2 bits (121), Expect = 4e-06
Identities = 72/336 (21%), Positives = 120/336 (35%), Gaps = 37/336 (11%)
Query: 551 PVPLDDSN----RPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQH 606
P+ ++ SN +P +T + A L +K+ +E +S P++ KS
Sbjct: 250 PLKINHSNNAIVKPPEMTP-QAAAKELEEVMKRVREAQSFISAAIEPESGKSNE------ 302
Query: 607 IVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRL 666
+ + S + + +++ HS R++S HR + S R+ R
Sbjct: 303 -------------RKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRR 349
Query: 667 AGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPK 726
+ K + +K R S D R K + KER K + R K+ + K
Sbjct: 350 RSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK 409
Query: 727 DYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSRE---EKESKKEREEEFKTHHEMKE 783
+ + K + + RE+D R+ EKE KE+E E E+ E
Sbjct: 410 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 469
Query: 784 YSGFAGVSR--PRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGS---SPKWNH 838
SR PR R +R R R + + R K+ S SP+ +
Sbjct: 470 KRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN 529
Query: 839 DK-----YQGDGIVEDEEETMENNEEKKDRCKEEKE 869
K + D I E E + K ++ KE
Sbjct: 530 KKDKKREKERDHISERRERERSTSMRKSSNDRDGKE 565
Score = 47.4 bits (111), Expect = 6e-05
Identities = 72/355 (20%), Positives = 123/355 (34%), Gaps = 42/355 (11%)
Query: 93 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 152
P + + R R RS +RS R S S R RS+ +RS RS S + SKSP
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354
Query: 153 VSKRRGSQEKQTKKAEGELQEE-----SPLKSKSQEEPKDTFEHDSSESIDEFNKSSATC 207
KR S+E++ ++ +++ +K K + + KD + E E K
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK----- 409
Query: 208 GDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 267
+ + ++ + +
Sbjct: 410 ----------ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 459
Query: 268 ERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQE 327
E+ S + + S+ P + SRRS +++ R+ R RS
Sbjct: 460 EKDRSKEIDEKRKKDKKSRTPPRSYNASRRS-------RSSSRERRRRRSR-----SSSR 507
Query: 328 TAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKES 387
+ +T K +KR + SR N +DK+ KE+ R E E ++ S+
Sbjct: 508 SPRTSKTIKR---KSSRSPSPRSRNKKDKKREKERDHISERRER--ERSTSMRKSSNDRD 562
Query: 388 GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSL 442
GK+K + +E E ++ SV K TEE +++ L
Sbjct: 563 GKEKL-EKNSTSLKEKEHNKEPDSSV----SKEVDDKDAPRTEENKIQHNGNCQL 612
Score = 42.7 bits (99), Expect = 0.001
Identities = 63/290 (21%), Positives = 101/290 (34%), Gaps = 32/290 (11%)
Query: 519 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 578
+ E+ R S R K +S K + NR S KDR + +
Sbjct: 300 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 359
Query: 579 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATE 638
K +E R K T E + VKE+ + ER +K
Sbjct: 360 KSRERRKSRSRSHSRDKRKDTREKIKEK-----ERVKEKDREKEREREKER--EKEKERG 412
Query: 639 EHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHR 698
++ R K E R D R+ + ++R ++E ++ +K R D +ID +
Sbjct: 413 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER--EKDRSKEIDEK 470
Query: 699 RKE---------------RSKERGDSKGSRESRGSRKQEKTPKDYKEYKSY--------K 735
RK+ RS+ + R SR S + +T K K S K
Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530
Query: 736 DDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYS 785
D K ++E+DH +S KE+ E+ T + KE++
Sbjct: 531 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHN 580
Score = 41.2 bits (95), Expect = 0.004
Identities = 71/356 (19%), Positives = 129/356 (36%), Gaps = 43/356 (12%)
Query: 417 QGKSFATA-----SHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPST 471
+ +SF +A S ++ E +G + +S K S K + K S
Sbjct: 284 EAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSR-----SH 338
Query: 472 TKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE--KSTFREES 529
+ + +++D+ + KK ++S E+ KS D + + +E K RE+
Sbjct: 339 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE 398
Query: 530 PLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDH 589
R K + R + K + + +R KDR H +++E D
Sbjct: 399 REREKEREKEKERGKNKDRDKE---REKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 455
Query: 590 IKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEI 649
K + +S + +++ KS S + +++ R++S
Sbjct: 456 EKEREKDRSKE----------IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSS 505
Query: 650 HRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDS 709
R S + RK +R + N+K K+ + + H + R +ERS S
Sbjct: 506 SRSPRTSKTIKRKSSRSPSP----RSRNKKDKKREK----ERDHISERRERERSTSMRKS 557
Query: 710 KGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEK 765
R+ G K EK KE +H +E D S+S +P + E K
Sbjct: 558 SNDRD--GKEKLEKNSTSLKE-------KEHNKEPDSSVSKEVD-DKDAPRTEENK 603
Score = 35.0 bits (79), Expect = 0.30
Identities = 97/441 (21%), Positives = 158/441 (35%), Gaps = 70/441 (15%)
Query: 377 EALDYFSDKESGKQKFNDSEGDDTEETE-DYRQFRKS-----VLADQGKSFATA----SH 426
+ L++F K+ G+ KF GD+T+ T + +F LA G F +H
Sbjct: 198 QLLEFF--KQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINH 255
Query: 427 RN---------TEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERP-----STT 472
N T + K +V +K RE+ F + E+G ER S T
Sbjct: 256 SNNAIVKPPEMTPQAAAKELEEV-MKRVREAQSFISAAIEP--ESGKSNERKGGRSRSHT 312
Query: 473 KDKHKEEDKNSERITVKKETQSPEQVKSE-----KLKDLFDYSPPLHKNLDAREKSTFRE 527
+ K + K+ R +K +QS + +S + KD P K +RE+ R
Sbjct: 313 RSKSRSSSKSHSR---RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS 369
Query: 528 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 587
S R K R ++K K V D + K+R +KE+E
Sbjct: 370 RSHSRDKR---KDTREKIKEKER-VKEKDREKEREREKER----------EKEKERGKNK 415
Query: 588 DHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSP 647
D K + + + + H K++ E+ K E R K
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRD--------KEKEKEQDKEKEREKDRSKEI 467
Query: 648 EIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKE------ 701
+ R+ D T + + R E ++ ++ R S R +RK
Sbjct: 468 DEKRKKDKKSRTPPRSYNASRRSRSSSRERRR--RRSRSSSRSPRTSKTIKRKSSRSPSP 525
Query: 702 RSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKD-DSKHKREQDHS--LSSSSSASPSS 758
RS+ + D K +E ++ + + KS D D K K E++ + + P S
Sbjct: 526 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 585
Query: 759 PSSREEKESKKEREEEFKTHH 779
S+E + R EE K H
Sbjct: 586 SVSKEVDDKDAPRTEENKIQH 606
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 79.7 bits (195), Expect = 1e-14
Identities = 86/332 (25%), Positives = 132/332 (39%), Gaps = 50/332 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRN 61
G+SN R RS+S ++S SRS S+SHSR+KR +S+ R+ S +RSR R ++
Sbjct: 182 GKSNERK-GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ---------KD 231
Query: 62 NRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 121
R + P+ R + R R +R HSR R+ K R
Sbjct: 232 RRRSKSPHKKRSKSR-------------ERRKSRSRSHSRDKRKDTREKIKEKERVKEKD 278
Query: 122 RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKS 181
R + R R R R + K + +E++ +K + +++ K K
Sbjct: 279 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KEKE 336
Query: 182 QEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCS 241
Q++ K+ E D S+ IDE K P S Y+ S RS S S+SSS S
Sbjct: 337 QDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRS-YNASRRSRSSSRERRRRRSRSSSRS 392
Query: 242 DAPMLSTVHSAKNTPSQHSHS------------IQHSPERSGSGSVGNGSS--------- 280
+ + +PS S + I ER S S+ S+
Sbjct: 393 PRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 452
Query: 281 RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDE 312
+ S S H+ S +K + ++APR E
Sbjct: 453 KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484
Score = 55.5 bits (132), Expect = 2e-07
Identities = 74/355 (20%), Positives = 131/355 (36%), Gaps = 42/355 (11%)
Query: 225 HSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRY-- 282
HS + I PP + + + + + S S +I+ PE S G SR
Sbjct: 139 HSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIE--PESGKSNERKGGRSRSHT 196
Query: 283 -SPSQNSPIHHIPSRRSPAKTIA-----PQNAPRDESRGRSSFYPDGGDQETAKTG---- 332
S S++S H +RS +K + ++ +D R +S +E K+
Sbjct: 197 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 256
Query: 333 -----KFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKES 387
K + E+ RV DR R++E +EK E+G+ + +++E D+E
Sbjct: 257 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKERE-----KDREK 311
Query: 388 GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYK---------- 437
K+K D E + +E E R K D+ K + +E+ K K
Sbjct: 312 DKEK--DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYN 369
Query: 438 -SKVSLKGNRESDGFREEKNDKHKETGYVVER-----PSTTKDKHKEEDKNSERITVKKE 491
S+ S +RE R + + T ++R PS K++ + ER + +
Sbjct: 370 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER 429
Query: 492 TQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVK 546
+ K + D L KN + ++ +E + D P +
Sbjct: 430 RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484
Score = 51.2 bits (121), Expect = 4e-06
Identities = 72/336 (21%), Positives = 120/336 (35%), Gaps = 37/336 (11%)
Query: 551 PVPLDDSN----RPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQH 606
P+ ++ SN +P +T + A L +K+ +E +S P++ KS
Sbjct: 134 PLKINHSNNAIVKPPEMTP-QAAAKELEEVMKRVREAQSFISAAIEPESGKSNE------ 186
Query: 607 IVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRL 666
+ + S + + +++ HS R++S HR + S R+ R
Sbjct: 187 -------------RKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRR 233
Query: 667 AGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPK 726
+ K + +K R S D R K + KER K + R K+ + K
Sbjct: 234 RSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK 293
Query: 727 DYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSRE---EKESKKEREEEFKTHHEMKE 783
+ + K + + RE+D R+ EKE KE+E E E+ E
Sbjct: 294 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 353
Query: 784 YSGFAGVSR--PRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGS---SPKWNH 838
SR PR R +R R R + + R K+ S SP+ +
Sbjct: 354 KRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN 413
Query: 839 DK-----YQGDGIVEDEEETMENNEEKKDRCKEEKE 869
K + D I E E + K ++ KE
Sbjct: 414 KKDKKREKERDHISERRERERSTSMRKSSNDRDGKE 449
Score = 47.4 bits (111), Expect = 6e-05
Identities = 72/355 (20%), Positives = 123/355 (34%), Gaps = 42/355 (11%)
Query: 93 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 152
P + + R R RS +RS R S S R RS+ +RS RS S + SKSP
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238
Query: 153 VSKRRGSQEKQTKKAEGELQEE-----SPLKSKSQEEPKDTFEHDSSESIDEFNKSSATC 207
KR S+E++ ++ +++ +K K + + KD + E E K
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK----- 293
Query: 208 GDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 267
+ + ++ + +
Sbjct: 294 ----------ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 343
Query: 268 ERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQE 327
E+ S + + S+ P + SRRS +++ R+ R RS
Sbjct: 344 EKDRSKEIDEKRKKDKKSRTPPRSYNASRRS-------RSSSRERRRRRSR-----SSSR 391
Query: 328 TAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKES 387
+ +T K +KR + SR N +DK+ KE+ R E E ++ S+
Sbjct: 392 SPRTSKTIKR---KSSRSPSPRSRNKKDKKREKERDHISERRER--ERSTSMRKSSNDRD 446
Query: 388 GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSL 442
GK+K + +E E ++ SV K TEE +++ L
Sbjct: 447 GKEKL-EKNSTSLKEKEHNKEPDSSV----SKEVDDKDAPRTEENKIQHNGNCQL 496
Score = 42.7 bits (99), Expect = 0.001
Identities = 63/290 (21%), Positives = 101/290 (34%), Gaps = 32/290 (11%)
Query: 519 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 578
+ E+ R S R K +S K + NR S KDR + +
Sbjct: 184 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 243
Query: 579 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATE 638
K +E R K T E + VKE+ + ER +K
Sbjct: 244 KSRERRKSRSRSHSRDKRKDTREKIKEK-----ERVKEKDREKEREREKER--EKEKERG 296
Query: 639 EHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHR 698
++ R K E R D R+ + ++R ++E ++ +K R D +ID +
Sbjct: 297 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER--EKDRSKEIDEK 354
Query: 699 RKE---------------RSKERGDSKGSRESRGSRKQEKTPKDYKEYKSY--------K 735
RK+ RS+ + R SR S + +T K K S K
Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414
Query: 736 DDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYS 785
D K ++E+DH +S KE+ E+ T + KE++
Sbjct: 415 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHN 464
Score = 41.2 bits (95), Expect = 0.004
Identities = 71/356 (19%), Positives = 129/356 (36%), Gaps = 43/356 (12%)
Query: 417 QGKSFATA-----SHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPST 471
+ +SF +A S ++ E +G + +S K S K + K S
Sbjct: 168 EAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSR-----SH 222
Query: 472 TKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE--KSTFREES 529
+ + +++D+ + KK ++S E+ KS D + + +E K RE+
Sbjct: 223 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE 282
Query: 530 PLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDH 589
R K + R + K + + +R KDR H +++E D
Sbjct: 283 REREKEREKEKERGKNKDRDKE---REKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 339
Query: 590 IKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEI 649
K + +S + +++ KS S + +++ R++S
Sbjct: 340 EKEREKDRSKE----------IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSS 389
Query: 650 HRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDS 709
R S + RK +R + N+K K+ + + H + R +ERS S
Sbjct: 390 SRSPRTSKTIKRKSSRSPSP----RSRNKKDKKREK----ERDHISERRERERSTSMRKS 441
Query: 710 KGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEK 765
R+ G K EK KE +H +E D S+S +P + E K
Sbjct: 442 SNDRD--GKEKLEKNSTSLKE-------KEHNKEPDSSVSKEVD-DKDAPRTEENK 487
Score = 35.0 bits (79), Expect = 0.30
Identities = 97/441 (21%), Positives = 158/441 (35%), Gaps = 70/441 (15%)
Query: 377 EALDYFSDKESGKQKFNDSEGDDTEETE-DYRQFRKS-----VLADQGKSFATA----SH 426
+ L++F K+ G+ KF GD+T+ T + +F LA G F +H
Sbjct: 82 QLLEFF--KQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINH 139
Query: 427 RN---------TEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERP-----STT 472
N T + K +V +K RE+ F + E+G ER S T
Sbjct: 140 SNNAIVKPPEMTPQAAAKELEEV-MKRVREAQSFISAAIEP--ESGKSNERKGGRSRSHT 196
Query: 473 KDKHKEEDKNSERITVKKETQSPEQVKSE-----KLKDLFDYSPPLHKNLDAREKSTFRE 527
+ K + K+ R +K +QS + +S + KD P K +RE+ R
Sbjct: 197 RSKSRSSSKSHSR---RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS 253
Query: 528 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 587
S R K R ++K K V D + K+R +KE+E
Sbjct: 254 RSHSRDKR---KDTREKIKEKER-VKEKDREKEREREKER----------EKEKERGKNK 299
Query: 588 DHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSP 647
D K + + + + H K++ E+ K E R K
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRD--------KEKEKEQDKEKEREKDRSKEI 351
Query: 648 EIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKE------ 701
+ R+ D T + + R E ++ ++ R S R +RK
Sbjct: 352 DEKRKKDKKSRTPPRSYNASRRSRSSSRERRR--RRSRSSSRSPRTSKTIKRKSSRSPSP 409
Query: 702 RSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKD-DSKHKREQDHS--LSSSSSASPSS 758
RS+ + D K +E ++ + + KS D D K K E++ + + P S
Sbjct: 410 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 469
Query: 759 PSSREEKESKKEREEEFKTHH 779
S+E + R EE K H
Sbjct: 470 SVSKEVDDKDAPRTEENKIQH 490
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 77.0 bits (188), Expect = 7e-14
Identities = 67/213 (31%), Positives = 96/213 (45%), Gaps = 19/213 (8%)
Query: 3 RSNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRD--RMYSRDYRR 57
R+ SRS ++ K S +R RSRS R +R RSR+ RSRS++ R ++YRR
Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRR 600
Query: 58 DYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRS 117
R+ RR GR R + R R R R+ R S+S K S
Sbjct: 601 RGRSRSRERRT--PPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENS 658
Query: 118 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS------QEKQTKKAEGEL 171
S +R S+SR S+ S + R SP+SK S + + K+ +K +
Sbjct: 659 ESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSV 718
Query: 172 QEESPLKSKSQE-----EPKDTFEHDSSESIDE 199
++E+ KSK QE E F+H+SS DE
Sbjct: 719 EKENQ-KSKGQENDHVHEKNKKFDHESSPGTDE 750
Score = 68.2 bits (165), Expect = 3e-11
Identities = 118/592 (19%), Positives = 222/592 (37%), Gaps = 83/592 (14%)
Query: 220 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGS 279
S S S S ++ SS SD+ + S K +S +H E+ +
Sbjct: 196 SSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSA 255
Query: 280 SRYSPSQNS----------------PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDG 323
S S ++N P + R+SP K + R+ R R P+
Sbjct: 256 SSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPN- 314
Query: 324 GDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFS 383
++ + +R S + RG R + S+ + ++ R E ++
Sbjct: 315 -----SQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRS------ETPPHWR 363
Query: 384 DKESGKQKFNDSEGD-----DTEETEDYRQFRKSVLADQGKSFATASHRNTEEE-GLKYK 437
+ Q+ S G+ D E + ++ ++S + + K HRN E K +
Sbjct: 364 QEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPV--RVKERKITDHRNVSESPNRKNE 421
Query: 438 SKVSLKGNRESDGFRE-----EKNDKHKETGYVVERP-STTKDKHKEEDKNSERITVKKE 491
+ +K ++ + R+ EK+DK+K V +R S ++ K KE+ K+ ER +
Sbjct: 422 KEKKVKDHKSNSKERDIRRNSEKDDKYKNK--VKKRAKSKSRSKSKEKSKSKERDSKHNR 479
Query: 492 TQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPE-VKLKMA 550
+ K +D + K D++ K R S + K + S S+ + K K
Sbjct: 480 NEEKRMRSRSKGRD-HENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEK 538
Query: 551 PVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSL 610
+R +TK + ++ + ++ RS + +S S+ +
Sbjct: 539 DRRAQSRSRECDITKGKHSYNSRTRERSRSRD-RSRRVRSRTHDRDRSRSKEY------- 590
Query: 611 VHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEE 670
H +EQ ++ R S + R +S + RR S S+ R++++ ++
Sbjct: 591 -HRYREQEYR-------RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKD 642
Query: 671 RVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKE 730
+ +E++ +K +S + R +S++ S SRE + R D
Sbjct: 643 KYRNQESKSSHRKENSES-------EKRMYSKSRDHNSSNNSREKKADR-------DQSP 688
Query: 731 YKSYKDDSKHKREQDHSLSSSSSASPSSPSSRE--EKESKKEREEEFKTHHE 780
+ K S QD+ L SS + R EKE++K + +E HE
Sbjct: 689 FSKIKQSS-----QDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHE 735
Score = 63.9 bits (154), Expect = 6e-10
Identities = 66/214 (30%), Positives = 94/214 (43%), Gaps = 36/214 (16%)
Query: 3 RSNSRSHSSRSKSRSQSSSRS----RSRSHSRKKRYRSRSRTYSRSRSRD---RMYSRDY 55
RS R H + + QS S+ RSRS + K+ S+S + S+S++ R SR
Sbjct: 488 RSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSR 547
Query: 56 R------------RDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP 103
R +R+ R R R + YHR YR RR RS
Sbjct: 548 ECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHR--YREQEYRRRGRSR 605
Query: 104 RR------GRSRSRSPKRR---SVSSQR--SRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 152
R GRSRS+ +RR S SS+R S+SR++ YR+ S +SS + +S K
Sbjct: 606 SRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQES-KSSHRKENSESEKRM 664
Query: 153 VSKRR---GSQEKQTKKAEGELQEESPLKSKSQE 183
SK R S + KKA+ + S +K SQ+
Sbjct: 665 YSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQD 698
Score = 57.8 bits (138), Expect = 4e-08
Identities = 56/217 (25%), Positives = 98/217 (45%), Gaps = 36/217 (16%)
Query: 3 RSNSRSHSS-RSKSRSQSS-----------SRSRSRSH----SRKKRYRSRSRTYSRSRS 46
+S SRS S +SKS+ + S SRS+ R H ++K+ S+ + RSRS
Sbjct: 457 KSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRS 516
Query: 47 RDR---MYSRDYRRDYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP 103
+++ + S+ D+ ++ R R R +G + +SR+
Sbjct: 517 KEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGK-------------HSYNSRTR 563
Query: 104 RRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQ 163
R RSR RS + RS + R RSRS+ +R RS S ++P + R ++
Sbjct: 564 ERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRR 623
Query: 164 TKK-AEGELQEESPLKSKSQ---EEPKDTFEHDSSES 196
++ + +EES ++K + +E K + ++SES
Sbjct: 624 RRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSES 660
Score = 57.4 bits (137), Expect = 6e-08
Identities = 124/604 (20%), Positives = 212/604 (35%), Gaps = 91/604 (15%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRS-----RSRDRMYSRDYRR 57
R NSR H K R +S + S S + + +S +R M +
Sbjct: 235 RKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKA 294
Query: 58 DYRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRS 117
D + + R R R Y R R + R + RG R R+P
Sbjct: 295 DEKERKNRERE---RERECNPPNSQPASYQR---RLLVTRSGRKIKGRGPRRYRTP---- 344
Query: 118 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPL 177
SRSRSR +R S +P S R + +++ E + + SP+
Sbjct: 345 -----SRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPV 399
Query: 178 KSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQS 237
+ K E K T + SES + N+ D H + ++
Sbjct: 400 RVK---ERKITDHRNVSESPNRKNEKEKKVKD---------------HKSNSKERDIRRN 441
Query: 238 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRR 297
S D AK+ S S ER S+++ ++ + R
Sbjct: 442 SEKDDKYKNKVKKRAKSKSRSKSKEKSKSKER---------DSKHNRNEEKRM------R 486
Query: 298 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKE 357
S +K +N E + S G DQE +++ +E L + N D
Sbjct: 487 SRSKGRDHENVKEKEKQSDSK----GKDQERSRS---------KEKSKQLESKSNEHDHS 533
Query: 358 ASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQ 417
SKEK RA+ + D GK +N + + + R+ R S D+
Sbjct: 534 KSKEKDR---RAQSRSRE-------CDITKGKHSYNSRTRERSRSRDRSRRVR-SRTHDR 582
Query: 418 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHK 477
+S + HR E+E + + + + R G K+ + + R S + ++ +
Sbjct: 583 DRSRSKEYHRYREQE-YRRRGRSRSRERRTPPGRSRSKDRRRR------RRDSRSSEREE 635
Query: 478 EEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPL-RIKMI 536
+ +N ++ ++ S + SE K ++ S + + ++REK R++SP +IK
Sbjct: 636 SQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQS 695
Query: 537 ASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQAS 596
+ D+ LK S+ K + + VH K+ FDH P
Sbjct: 696 SQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKK------FDHESSPGTD 749
Query: 597 KSTS 600
+ S
Sbjct: 750 EDKS 753
Score = 50.1 bits (118), Expect = 9e-06
Identities = 118/602 (19%), Positives = 212/602 (35%), Gaps = 97/602 (16%)
Query: 296 RRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRD 355
+R + + + ++ +S S D D E+A K KR R N+R
Sbjct: 189 KRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKH--------RKNSRK 240
Query: 356 --KEASKEKGSEKGRA-EGEWEDQEALD----------------YFSDKESGKQKFNDSE 396
KE K K S+K + E E E+ EA + K K + +
Sbjct: 241 HKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERK 300
Query: 397 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEG-LKYKSKVSLKGNRESDGFREEK 455
+ E + + Q + T S R + G +Y++ +R D FR +
Sbjct: 301 NRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTP---SRSRSRDRFRRSE 357
Query: 456 NDKH-KETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSP-PL 513
H ++ +R + + + SE +K+ +SP +VK K+ D + S P
Sbjct: 358 TPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPN 417
Query: 514 HKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 573
KN +EK +S + + I +S + + +R S K +
Sbjct: 418 RKN--EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDS 475
Query: 574 VHSVKKEQEFRSIF---DHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERF 630
H+ +E+ RS DH + + K + K+Q +S + S++
Sbjct: 476 KHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKG-----------KDQE-RSRSKEKSKQL 523
Query: 631 TSYQKATEEHSTRQKSPEIH---RRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCD 687
S + +++K R DI+ ++R +E ++ D+ R
Sbjct: 524 ESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRT-------RERSRSRDRSRRVR 576
Query: 688 SADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHS 747
S HD D R + + + R R ++ +TP +S D + +R S
Sbjct: 577 SRT--HDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPG----RSRSKDRRRRRRDSRS 630
Query: 748 LSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDY 807
S S + R ++ R+E + E + YS SR + ++ R+ D
Sbjct: 631 SEREESQSRNKDKYRNQESKSSHRKE--NSESEKRMYS----KSRDHNSSNNSREKKAD- 683
Query: 808 WAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETMENNEEKKDRCKEE 867
R + F K S + N E + ++N E++K R E
Sbjct: 684 --------------RDQSPFSKIKQSSQDN----------ELKSSMLKNKEDEKIRSSVE 719
Query: 868 KE 869
KE
Sbjct: 720 KE 721
Score = 42.0 bits (97), Expect = 0.002
Identities = 46/215 (21%), Positives = 85/215 (39%), Gaps = 23/215 (10%)
Query: 674 KEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKS 733
K+E +K K S+ + S + DS+ + E + ++++K K+ +++K
Sbjct: 184 KKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKK 243
Query: 734 YKDDSKHKREQDHSLSSSSS--ASPSSPSSREE------------KESKKEREEEFKTHH 779
K K ++ S S + + A P S EE K K E+E K
Sbjct: 244 EKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRE 303
Query: 780 EMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRG-----TFQRGRGRFNFKKSGSSP 834
+E S+P R V ++ +GRG T R R R F++S + P
Sbjct: 304 RERERECNPPNSQPASY---QRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPP 360
Query: 835 KWNHDKYQGDGI-VEDEEETMENNEEKKDRCKEEK 868
W + + + V E ++ ++ + + KE +
Sbjct: 361 HWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQ 395
Score = 39.3 bits (90), Expect = 0.016
Identities = 26/118 (22%), Positives = 46/118 (38%), Gaps = 9/118 (7%)
Query: 666 LAGEERVFKEENQKGD---------KKLRCDSADLRHDIDHRRKERSKERGDSKGSRESR 716
++G+E V + ENQK D + L C + + K+R K S S
Sbjct: 145 ISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDS 204
Query: 717 GSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEE 774
S ++ D + +S ++ KR++ H +S + +K + E E E
Sbjct: 205 DSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAE 262
Score = 34.3 bits (77), Expect = 0.51
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 6/92 (6%)
Query: 698 RRKERSKERGDSKGSRESRGSRKQEKTPK------DYKEYKSYKDDSKHKREQDHSLSSS 751
R E K SK E R E PK + K +KS S + D S S
Sbjct: 152 REIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQ 211
Query: 752 SSASPSSPSSREEKESKKEREEEFKTHHEMKE 783
SS+ S S E++SKK +++ K + K+
Sbjct: 212 SSSDSSDSESATEEKSKKRKKKHRKNSRKHKK 243
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 76.6 bits (187), Expect = 9e-14
Identities = 132/669 (19%), Positives = 210/669 (31%), Gaps = 16/669 (2%)
Query: 108 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRS-SSPYSKSPVSKRRGSQEKQTKK 166
S S S SS S S S S SS S S S S SS S S S +
Sbjct: 552 SDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611
Query: 167 AEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHS 226
+ + S KS S + E DSS+S + + S + D + D S S S
Sbjct: 612 DSSDSSDSSDSKSDSSKS-----ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 227 PSPIATPPSQSSSCSDAPM---LSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYS 283
S ++ S SSS SD+ S + N+ S + S S N +S S
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Query: 284 PSQNSPIHHIPSRRSPAKTIAPQNAPRDES----RGRSSFYPDGGDQETAKTGKFLKRFT 339
S NS S S + + + D S SS D D +
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786
Query: 340 DEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDD 399
D + D N+ D S + ++ + + SD + S+ D
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846
Query: 400 TEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKH 459
+ + D +S ++ S ++ N+ + S S + SD +D
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906
Query: 460 KETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPL-HKNLD 518
+ S+ E +S+ + S + S + D S N
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 519 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 578
S + S +SDS + + +S + D +S +S
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD 1026
Query: 579 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATE 638
S D +S S+ S + ++ + +S +
Sbjct: 1027 SSNSSDS-SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085
Query: 639 EHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHR 698
+ S S + D S S+ D+ + + + D DS+D + D
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 699 RKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSS 758
S + DS S +S S D + + D S D S SS SS S S
Sbjct: 1146 DSSESSDSSDSSDSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204
Query: 759 PSSREEKES 767
S + +S
Sbjct: 1205 SDSSDSSDS 1213
Score = 63.2 bits (152), Expect = 1e-09
Identities = 101/511 (19%), Positives = 156/511 (30%), Gaps = 30/511 (5%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYR-RDYRNN 62
S+ S SS S S SS+ S S S S + S S D S D D N+
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823
Query: 63 RAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 122
G NR S + S S S
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883
Query: 123 SRSRSRRSYRSSRSPRSSSSRSS--------SPYSKSPVSKRRGSQEKQTKKAEGELQEE 174
+ S S SS S SS S SS S S S S + + ++ +
Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943
Query: 175 SPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPP 234
S S S + DSS S D + +S+ D + D S S S S ++
Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003
Query: 235 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIP 294
S SS SD+ S + N+ + S S S + SS S S NS
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063
Query: 295 SRRSPAKTIAPQNAPRDESRGR-------------------SSFYPDGGDQETAKTGKFL 335
S S + + + D S SS D D +
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123
Query: 336 KRFTDEESRVFLLDRGNTRDKEASKEKG--SEKGRAEGEWEDQEALDYFSDKESGKQKFN 393
+D D N+ D S E S+ + + ++ D +S +
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183
Query: 394 DSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFRE 453
D ++ ++ S +D S ++ ++ + S S + + SD
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243
Query: 454 EKNDKHKETGYVVERPSTTKDKHKEEDKNSE 484
+ ++ + +T D + E D S+
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Score = 52.4 bits (124), Expect = 2e-06
Identities = 87/395 (22%), Positives = 120/395 (30%), Gaps = 25/395 (6%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA 64
NS S S + S S SS S + S S S S S S S D S + ++ +
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
N S + S S S
Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051
Query: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEE 184
S S S SS S SS S SS S S S + ++ +S S S +
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111
Query: 185 PKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAP 244
+ DSS S D + S ++ D ++ D S S S S ++ S SS SD+
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSS--DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 245 MLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIA 304
S + N+ S S S + SS S S +S S S + +
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Query: 305 PQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS 364
N D S D D + +D +T D + S
Sbjct: 1230 DSNESSDSS--------DSSDSSDSSNSSDSSDSSDSSD--------STSDSNDESDSQS 1273
Query: 365 EKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDD 399
+ G D SD +S N S DD
Sbjct: 1274 KSGNGNNNGSD-------SDSDSEGSDSNHSTSDD 1301
Score = 52.0 bits (123), Expect = 2e-06
Identities = 127/715 (17%), Positives = 231/715 (32%), Gaps = 64/715 (8%)
Query: 120 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYS-----------KSPVSKRR--------GSQ 160
SQR + ++R S+ + ++ S ++ K P S R G++
Sbjct: 338 SQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNE 397
Query: 161 EKQTKKAEGELQEESPLKSKSQ----EEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSA 216
K+ K G + + +K++ + E P E + N S + D G +
Sbjct: 398 GKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSE--PGNKVGHSNTGSDSNSD---GYDS 452
Query: 217 YDXSPRSPHSPSPIATPPSQ------------SSSCSDAPMLSTVHSAKNTPSQH----- 259
YD +S P ++ S SSS DA S S
Sbjct: 453 YDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAED 512
Query: 260 ----SHSIQHSPERSGSGSVGNGSSRYSPS--QNSPIHHIPSRRSPAKTIAPQNAPRDES 313
S S ++ + +G+G+ GN + S S S S S + + ++ D S
Sbjct: 513 DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS 572
Query: 314 RGRSSFYPDGGDQETAKTGKFLKRFTDEES-RVFLLDRGNTRDKEASKEKGSEKGRAEGE 372
SS D D +++ + + S D ++ D S + S+ ++E +
Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
Query: 373 WEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEE 432
D ++ SD S N D + + S +D S +++ ++ +
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692
Query: 433 GLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVE--RPSTTKDKHKEEDKNSERITVKK 490
S S + SD + +D + S + D D +S+
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD-SSDSSDSSN 751
Query: 491 ETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMA 550
+ S + S D D S + D+ + S + + +SDS +
Sbjct: 752 SSDSSDSSDSSNSSDSSDSS----DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807
Query: 551 PVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSL 610
D S+ S D +S +S S + S S+S + S
Sbjct: 808 ----DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN 863
Query: 611 VHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEE 670
+ S + S+ S + + S+ + D S S+ D+ + +
Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923
Query: 671 RVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKE 730
+ + +S+D D S DS S +S S + +
Sbjct: 924 SESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983
Query: 731 YKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYS 785
S DS + S S+SS +S SS SS S + + + S
Sbjct: 984 DSSDSSDSSDSSDSSDS-SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 75.9 bits (185), Expect = 2e-13
Identities = 63/149 (42%), Positives = 70/149 (46%), Gaps = 29/149 (19%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
RS SRS SRS SRS S S SRSRS RSRSR+ S S+SR R SR+
Sbjct: 203 RSKSRSSHSRSSSRSSSPSSSRSRS-------RSRSRSSSSSQSRSRSSSRE-------- 247
Query: 63 RAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN--RRHSRSPRRGRSRSRSPKRRSVSS 120
R R RG R HRG P S SP R R RSRS S
Sbjct: 248 ---------RSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDR 298
Query: 121 QRSRSRSR---RSYRSSRSPRSSSSRSSS 146
++ R+RSR R +RSS S SRSSS
Sbjct: 299 KKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
Score = 51.6 bits (122), Expect = 3e-06
Identities = 36/93 (38%), Positives = 47/93 (50%), Gaps = 9/93 (9%)
Query: 100 SRSPRRGRSRSRSPKRRSVSSQ---------RSRSRSRRSYRSSRSPRSSSSRSSSPYSK 150
S SP RSRSRS R S SSQ RSRSR +S SSRS R SSS YS
Sbjct: 217 SSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSS 276
Query: 151 SPVSKRRGSQEKQTKKAEGELQEESPLKSKSQE 183
S S R + +++ + +++ +S+S E
Sbjct: 277 SSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPE 309
Score = 48.1 bits (113), Expect = 3e-05
Identities = 48/212 (22%), Positives = 83/212 (39%), Gaps = 14/212 (6%)
Query: 634 QKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGD-KKLRCDSADLR 692
+++ E+ + + +R + P+++ K+ +E +EE++ D K + D +
Sbjct: 118 EESDGEYDEFGRKKKKYRGKAVGPASILKEVE--DKESEGEEEDEDEDLSKYKLDEDEDE 175
Query: 693 HDIDHRRKER-SKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSS 751
D D + + E DS + +R SR + ++ +S S R + S SSS
Sbjct: 176 DDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235
Query: 752 SSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKR 811
SS S S SSRE S+ + H G S PR + + KR
Sbjct: 236 SSQSRSRSSSRERSRSRGSKSRSSSRSHR--------GSSSPRKRSYSSSSSSPERNRKR 287
Query: 812 GRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQG 843
R R + R + + SP+ H G
Sbjct: 288 SRSRSSSSGDRKK--RRTRSRSPERRHRSSSG 317
Score = 47.4 bits (111), Expect = 6e-05
Identities = 41/124 (33%), Positives = 51/124 (41%), Gaps = 1/124 (0%)
Query: 85 RYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRS 144
R R R +R SRS SRSRS + RS SS S+SRSR S R R S SRS
Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRS-RSRSRSSSSSQSRSRSSSRERSRSRGSKSRS 258
Query: 145 SSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSS 204
SS + S R+ S + E + S S + K S E + S
Sbjct: 259 SSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGS 318
Query: 205 ATCG 208
+ G
Sbjct: 319 SHSG 322
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/97 (37%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 101 RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 160
+S RR RS+SRS RS SS+ S S RS SRS SSSS+S S S S+ RGS+
Sbjct: 197 KSNRRSRSKSRSSHSRS-SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSK 255
Query: 161 EKQTKKA-EGELQEESPLKSKSQEEPKDTFEHDSSES 196
+ + ++ G S S P+ + S S
Sbjct: 256 SRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRS 292
Score = 42.4 bits (98), Expect = 0.002
Identities = 43/133 (32%), Positives = 54/133 (40%), Gaps = 8/133 (6%)
Query: 108 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG-SQEKQTKK 166
S + RRS S RS S SR S RSS SP SS SRS S S S+ R S ++ +
Sbjct: 193 SNKKKSNRRSRSKSRS-SHSRSSSRSS-SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSR 250
Query: 167 AEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHS 226
+ G S + P+ SS S + K S + S+ D R S
Sbjct: 251 SRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSS-----SSGDRKKRRTRS 305
Query: 227 PSPIATPPSQSSS 239
SP S S S
Sbjct: 306 RSPERRHRSSSGS 318
Score = 41.2 bits (95), Expect = 0.004
Identities = 54/193 (27%), Positives = 82/193 (42%), Gaps = 22/193 (11%)
Query: 143 RSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNK 202
R Y V +E + K++EGE ++E SK + D E + + ++N
Sbjct: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYK---LDEDEDEDDADLSKYNL 185
Query: 203 SSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS---AKNTPSQH 259
++ D S S R S S + S+SSS S +P S S ++++ S
Sbjct: 186 DASEEED-----SNKKKSNRRSRSKS--RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQ 238
Query: 260 SHSIQHSPERSGS-GSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSS 318
S S S ERS S GS SSR +SP +RS + + + R SR RSS
Sbjct: 239 SRSRSSSRERSRSRGSKSRSSSRSHRGSSSP-----RKRSYSSSSSSPERNRKRSRSRSS 293
Query: 319 FYPDGGDQETAKT 331
GD++ +T
Sbjct: 294 ---SSGDRKKRRT 303
Score = 40.0 bits (92), Expect = 0.009
Identities = 42/154 (27%), Positives = 58/154 (37%), Gaps = 13/154 (8%)
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLK 178
+S+ S ++S R SRS SS SS S SP S R S+ + + +S +
Sbjct: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS----SSQSRSR 242
Query: 179 SKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSS 238
S S+E + S S SS P +Y S SP + S+SS
Sbjct: 243 SSSRERSRSRGSKSRSSSRSHRGSSS-------PRKRSYSSSSSSPERNRKRSR--SRSS 293
Query: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 272
S D T + + S HS RS S
Sbjct: 294 SSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
Score = 35.4 bits (80), Expect = 0.23
Identities = 36/154 (23%), Positives = 58/154 (37%), Gaps = 23/154 (14%)
Query: 615 KEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFK 674
K+ +S + + S S +++ S+R +S R S S R +R R K
Sbjct: 196 KKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSK 255
Query: 675 EENQ----KGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKE 730
+ +G R S R ++RS+ R S G R+ R +R +
Sbjct: 256 SRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP------- 308
Query: 731 YKSYKDDSKHKREQDHSLSSSSSASPSSPSSREE 764
E+ H SS SS S S SS+++
Sbjct: 309 ------------ERRHRSSSGSSHSGSRSSSKKK 330
Score = 32.7 bits (73), Expect = 1.5
Identities = 29/143 (20%), Positives = 48/143 (33%), Gaps = 9/143 (6%)
Query: 636 ATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDI 695
A+EE + +K R S R +R + + + R S+
Sbjct: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPS----SSRSRSRSRSRSSSSS----- 237
Query: 696 DHRRKERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSAS 755
R + S+ER S+GS+ SR + K S S + + SSSS
Sbjct: 238 QSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
Query: 756 PSSPSSREEKESKKEREEEFKTH 778
+R ++ R +H
Sbjct: 298 RKKRRTRSRSPERRHRSSSGSSH 320
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 73.2 bits (178), Expect = 1e-12
Identities = 60/175 (34%), Positives = 78/175 (44%), Gaps = 16/175 (9%)
Query: 13 SKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRAMRRPYGYR 72
S RS S SRSRSRS ++R RSRSR SRSRSR SR R R+ R G +
Sbjct: 186 SHRRSYSGSRSRSRS---RRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK 242
Query: 73 GRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYR 132
R + + R R + +S R RSRSRSPK +S+SRSR
Sbjct: 243 SRSKSKSKPKSDRGSHSHSRSRSKDEYEKS--RSRSRSRSPKENGKGDIKSKSRSR---- 296
Query: 133 SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKD 187
S SRS+SP P R S + + + S +S+S+ +D
Sbjct: 297 -------SQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
Score = 68.9 bits (167), Expect = 2e-11
Identities = 60/180 (33%), Positives = 82/180 (45%), Gaps = 17/180 (9%)
Query: 99 HSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 158
+ R+ R + R+ RRS S RSRSRSRR RS RS RSS SRS S +SK R
Sbjct: 172 NGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRS-RSRRSSRSRSRS------ISKSRS 224
Query: 159 SQEKQTKKAEGELQEESPLKSKSQEEPKD---TFEHDSSESIDEFNKSSATCGDIWP--- 212
++K + +SKS+ +PK + H S S DE+ KS + P
Sbjct: 225 RSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKEN 284
Query: 213 ---GLSAYDXSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPER 269
+ + S S SP+ PPS++ S S P +T S + S+ S S S R
Sbjct: 285 GKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSK-SRSRSRSSSR 343
Score = 63.5 bits (153), Expect = 8e-10
Identities = 58/154 (37%), Positives = 76/154 (49%), Gaps = 30/154 (19%)
Query: 3 RSNSRSHS-SRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRR---D 58
R +SRS S S SKSRS+S SRS+ RS SR K +SRS++ S+ +S +S R +
Sbjct: 209 RRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDE 268
Query: 59 YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSP----- 113
Y +R+ R + G+G + S+S R +SRS SP
Sbjct: 269 YEKSRSRSRSRSPKENGKGDIK-------------------SKSRSRSQSRSNSPLPVPP 309
Query: 114 -KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 146
K RSVS R+ SR R SRS S SRSSS
Sbjct: 310 SKARSVSPPPKRATSRSRSR-SRSKSRSRSRSSS 342
Score = 32.0 bits (71), Expect = 2.6
Identities = 32/122 (26%), Positives = 47/122 (38%), Gaps = 9/122 (7%)
Query: 660 LRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRR---KERSKERGDSKGSRESR 716
L +D R + + + R S R R K RS+ R SKG SR
Sbjct: 178 LIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSR 237
Query: 717 --GSRKQEKT---PKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKER 771
G + + K+ PK + S+ S+ K E + S S S S SP + K + R
Sbjct: 238 SKGRKSRSKSKSKPKSDRGSHSH-SRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSR 296
Query: 772 EE 773
+
Sbjct: 297 SQ 298
Score = 31.6 bits (70), Expect = 3.3
Identities = 34/134 (25%), Positives = 46/134 (34%), Gaps = 18/134 (13%)
Query: 700 KERSKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSP 759
K R+ R GSR SR+ +S + R + S+S S S S S
Sbjct: 182 KPRTSHRRSYSGSRSRSRSRR-----------RSRSRSRRSSRSRSRSISKSRSRSRSRS 230
Query: 760 SSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQ 819
R S K R+ K+ + K G SR R D + R R R +
Sbjct: 231 KGRSRSRS-KGRKSRSKSKSKPKSDRGSHSHSRSRS------KDEYEKSRSRSRSRSPKE 283
Query: 820 RGRGRFNFKKSGSS 833
G+G K S
Sbjct: 284 NGKGDIKSKSRSRS 297
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 73.2 bits (178), Expect = 1e-12
Identities = 118/524 (22%), Positives = 204/524 (38%), Gaps = 70/524 (13%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
R R ++ R + R R R R++R R R R + R + R R ++ R+
Sbjct: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQRR-KEEWERERAKR 460
Query: 63 RAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRS-------------- 108
R + R R + + G R P R + P++ +
Sbjct: 461 DEKDRQHRDRDREKEREKEKGKPKPRSPQPP---SRQAEPPKKEAATTGPQVKRADEWKD 517
Query: 109 ---RSRSPKRR-SVSSQRSRSRSRRSYRSSRSPRSSSSRSSS---PYSKSPVSKRRGSQE 161
RS+SPK++ VS SR+R RR +S + S+SSRSSS YS S S+ R
Sbjct: 518 PWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSS 577
Query: 162 KQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSP 221
+ + + S S+S+ + S + S T G+ P
Sbjct: 578 SYSSYSSRSSRHSSFSGSRSRSRSFSS-SPSPSPTPSPHRPSIRTKGE--PAPPPGKAGE 634
Query: 222 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPER----SGSGSVGN 277
+S P+P PP + + AP+ ++ +P R SGSGS G+
Sbjct: 635 KSVKKPAPPPAPPQATKTT--APVPEPTKPGDPREARRKERPARTPPRRRTLSGSGS-GS 691
Query: 278 GSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKR 337
GSS YS S S RS + +++ ++ + SS + +
Sbjct: 692 GSS-YSGS---------SSRSRSLSVSSVSSVSSATSSSSSAHSVDSED----------M 731
Query: 338 FTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEG 397
+ D S V + + KEKG K + +G E++ D S + K + G
Sbjct: 732 YADLASPVSSASSRSPAPAQTRKEKGKSK-KEDGVKEEKRKRD--SSTQPPKSAKPPAGG 788
Query: 398 DDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKND 457
+++ +Q Q + +H+ + L +K + KG+R+ R E +D
Sbjct: 789 KSSQQPSTPQQAPPG----QPQQGTFVAHKEIK---LTLLNKAADKGSRK----RYEPSD 837
Query: 458 KHKETGYVVERPSTTKDKHKEEDKNSERI-TVKKETQSPEQVKS 500
K +++ +RP+T+ D+ + K+ R+ + K E Q + K+
Sbjct: 838 KDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKA 881
Score = 48.9 bits (115), Expect = 2e-05
Identities = 59/256 (23%), Positives = 92/256 (35%), Gaps = 26/256 (10%)
Query: 86 YHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSS 145
YH R R +R R R R R +R +R R R + + + R
Sbjct: 398 YHNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERER 457
Query: 146 SPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQEEPKDTFEHDSSESIDEFNKSSA 205
+ + R +EK+ +K +G+ + SP Q EP K +A
Sbjct: 458 AKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPP--------------KKEAA 503
Query: 206 TCG------DIWPGLSAYDXSPRSP--HSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS 257
T G D W SP+ S SP + +S S A ++ S+ + S
Sbjct: 504 TTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSS 563
Query: 258 QHSHSIQHSPERSGS-GSVGNGSSRYS--PSQNSPIHHIPSRRSPAKTIAPQNAPRDESR 314
S RS S S + SSR+S S S SP+ T +P + P ++
Sbjct: 564 YSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSP-HRPSIRTK 622
Query: 315 GRSSFYPDGGDQETAK 330
G + P +++ K
Sbjct: 623 GEPAPPPGKAGEKSVK 638
Score = 48.9 bits (115), Expect = 2e-05
Identities = 92/326 (28%), Positives = 116/326 (35%), Gaps = 40/326 (12%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRN 61
G S SRS SS S SS SRS HS RSRSR++S S S S +R R
Sbjct: 568 GSSRSRSRSS-----SYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPS-PHRPSIRT 621
Query: 62 NRAMRRPYGYRGRG--RGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR----SPKR 115
P G G + PV PR R + R P+R
Sbjct: 622 KGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRR 681
Query: 116 RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEES 175
R++S S S S S SSRS S S SS S + S S + + A+ S
Sbjct: 682 RTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYAD----LAS 737
Query: 176 PLKSKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPS 235
P+ S S P +++ E KS G+ S P A PP+
Sbjct: 738 PVSSASSRSPA------PAQTRKEKGKSKKE-----DGVKEEKRKRDSSTQPPKSAKPPA 786
Query: 236 QSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG--SGSVGNGS-SRYSPSQNSPIHH 292
S S P ST A Q + H + + + GS RY PS
Sbjct: 787 GGKS-SQQP--STPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDK----- 838
Query: 293 IPSRRSPAKTIAPQNAPRDESRGRSS 318
R+SP P +P SR R S
Sbjct: 839 --DRQSPPPAKRPNTSPDRGSRDRKS 862
Score = 42.0 bits (97), Expect = 0.002
Identities = 50/223 (22%), Positives = 81/223 (36%), Gaps = 20/223 (8%)
Query: 625 TLSERFTSYQKATEEHS--TRQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDK 682
T +E + +Y++ E RQ+ E R D +++ E KE ++ ++
Sbjct: 393 TETEPYHNYRERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEE 452
Query: 683 KLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSR---KQEKTPK--------DYKEY 731
R + D HR ++R KER KG + R + +Q + PK K
Sbjct: 453 WERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRA 512
Query: 732 KSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVS 791
+KD + + L S S S + R+ S ++ YSG +G S
Sbjct: 513 DEWKDPWRRSKSPKKKLGVSVSPS-RARRRRKTSASSASASNSSRSSSRSSSYSG-SGSS 570
Query: 792 RPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP 834
R R R ++ R +F R R S SP
Sbjct: 571 RSR-----SRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSP 608
Score = 31.6 bits (70), Expect = 3.3
Identities = 31/128 (24%), Positives = 42/128 (32%), Gaps = 24/128 (18%)
Query: 643 RQKSPEIHRRIDISPSTLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKER 702
R KSP+ + +SPS R+ +K SA + R
Sbjct: 521 RSKSPKKKLGVSVSPSRARRR------------------RKTSASSASASNS------SR 556
Query: 703 SKERGDSKGSRESRGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSR 762
S R S S SR + + Y S R + S SSS S SP+ R
Sbjct: 557 SSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHR 616
Query: 763 EEKESKKE 770
+K E
Sbjct: 617 PSIRTKGE 624
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 72.4 bits (176), Expect = 2e-12
Identities = 66/208 (31%), Positives = 95/208 (45%), Gaps = 45/208 (21%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
R R R K R + R + R+ R++R RSRSR+ SR+ DR SR RD++ +
Sbjct: 261 REREREERER-KRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRS--RDHKRS 317
Query: 63 RAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 122
R+ R R R R + +R H RS R+ RSRSR +R
Sbjct: 318 RSRERR---RSRSRDRRR---------------SRSHDRSERKHRSRSRDRRR------- 352
Query: 123 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQ 182
S+SR R+SY+ S SR KS ++RGS +K +S +KS S+
Sbjct: 353 SKSRDRKSYK-----HRSKSRDREQDRKSKEKEKRGSDDK-----------KSSVKSGSR 396
Query: 183 EEPKDTFEHDSSESIDEFNKSSATCGDI 210
E+ + +S ES D N+ + T DI
Sbjct: 397 EKQSEDTNTESKES-DTKNEVNGTSEDI 423
Score = 43.9 bits (102), Expect = 6e-04
Identities = 65/310 (20%), Positives = 120/310 (38%), Gaps = 38/310 (12%)
Query: 578 KKEQEFRSIFDHIK--LPQASKSTSESFI---QHIVSLVHHVKEQYFKSAAMTLSERFTS 632
K E++ + + D I L Q + SE + Q ++ LV +KE+ E S
Sbjct: 124 KNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEE---------RELLRS 174
Query: 633 YQKATEEHSTRQKSPEIHRR----IDISPSTLRKDTRLAGEERV----FKEENQKGDKKL 684
E + ++K E+ + + + R D L G++ + K ++ +KL
Sbjct: 175 TTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKL 234
Query: 685 RCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRKQEK--TPKDYKEYKSYKDDSKHKR 742
R + + D D R K+ +ER + + RE ++ K ++ +E + +D + KR
Sbjct: 235 RKRTEE--PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKR 292
Query: 743 EQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRD 802
+ S SS ++ SR+ K S+ ++ + S + R D R
Sbjct: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR- 351
Query: 803 DGVDYWAKRGRGRGTFQ---RGRGRFNFKKSGSSPKWNHDKYQGDGIVEDEEETME--NN 857
+ R R +++ + R R +KS K D + E+ E N
Sbjct: 352 ------RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405
Query: 858 EEKKDRCKEE 867
E K+ K E
Sbjct: 406 ESKESDTKNE 415
Score = 38.1 bits (87), Expect = 0.036
Identities = 43/180 (23%), Positives = 73/180 (40%), Gaps = 11/180 (6%)
Query: 335 LKRFTDEESRVFLLDRGNTRDKEASKEKGSEKG-------RAEGEWEDQEALDYFSDKES 387
L++ T+E R L + +E KE+ E+ R E E E + A D K S
Sbjct: 234 LRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRS 293
Query: 388 GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRE 447
+ + S D + R ++S ++ +S + R+ + + K + + R
Sbjct: 294 RSRSRHSSRTSDRRCSRS-RDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRR 352
Query: 448 SDGFREEKNDKH--KETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKD 505
S R+ K+ KH K +R S K+K +DK S + +E QS + K D
Sbjct: 353 SKS-RDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.123 0.344
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,431,896
Number of Sequences: 37866
Number of extensions: 2008222
Number of successful extensions: 33802
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 394
Number of HSP's successfully gapped in prelim test: 991
Number of HSP's that attempted gapping in prelim test: 14019
Number of HSP's gapped (non-prelim): 10090
length of query: 869
length of database: 18,247,518
effective HSP length: 111
effective length of query: 758
effective length of database: 14,044,392
effective search space: 10645649136
effective search space used: 10645649136
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.