BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase ACSM2B, mitochondrial isoform 1 [Homo sapiens] (571 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 1165 0.0 gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 1165 0.0 gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 1103 0.0 gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 1103 0.0 gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 1079 0.0 gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 637 0.0 gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 609 e-174 gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 597 e-170 gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 592 e-169 gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 394 e-109 gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 344 1e-94 gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 155 9e-38 gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom... 139 5e-33 gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 136 5e-32 gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 135 1e-31 gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 109 6e-24 gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 109 6e-24 gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 107 4e-23 gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 92 2e-18 gi|40807357 solute carrier family 27 (fatty acid transporter), m... 71 3e-12 gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 64 3e-10 gi|62865631 solute carrier family 27 (fatty acid transporter), m... 61 3e-09 gi|13325055 solute carrier family 27 (fatty acid transporter), m... 61 3e-09 gi|209529739 hypothetical protein LOC100132247 [Homo sapiens] 57 3e-08 gi|239745501 PREDICTED: similar to acyl-CoA synthetase medium-ch... 57 3e-08 gi|239745482 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08 gi|157074225 nuclear pore complex interacting protein-like 3 [Ho... 57 3e-08 gi|239745430 PREDICTED: hypothetical protein XP_002343465 [Homo ... 56 1e-07 gi|239745418 PREDICTED: similar to GPS, PLAT and transmembrane d... 56 1e-07 gi|239745416 PREDICTED: similar to GPS, PLAT and transmembrane d... 56 1e-07 >gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase ACSM2B, mitochondrial isoform 2 [Homo sapiens] Length = 571 Score = 1165 bits (3013), Expect = 0.0 Identities = 571/571 (100%), Positives = 571/571 (100%) Query: 1 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA Sbjct: 1 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60 Query: 61 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWW 120 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWW Sbjct: 61 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWW 120 Query: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK Sbjct: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180 Query: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL Sbjct: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240 Query: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL Sbjct: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300 Query: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF Sbjct: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360 Query: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIAFVHGSPRAGDLGFAGTMTLSFCGH 420 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIAFVHGSPRAGDLGFAGTMTLSFCGH Sbjct: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIAFVHGSPRAGDLGFAGTMTLSFCGH 420 Query: 421 QENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHP 480 QENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHP Sbjct: 421 QENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHP 480 Query: 481 AVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEF 540 AVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEF Sbjct: 481 AVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEF 540 Query: 541 VLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 571 VLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ Sbjct: 541 VLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 571 >gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase ACSM2B, mitochondrial isoform 1 [Homo sapiens] Length = 571 Score = 1165 bits (3013), Expect = 0.0 Identities = 571/571 (100%), Positives = 571/571 (100%) Query: 1 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA Sbjct: 1 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60 Query: 61 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWW 120 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWW Sbjct: 61 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWW 120 Query: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK Sbjct: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180 Query: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL Sbjct: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240 Query: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL Sbjct: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300 Query: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF Sbjct: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360 Query: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIAFVHGSPRAGDLGFAGTMTLSFCGH 420 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIAFVHGSPRAGDLGFAGTMTLSFCGH Sbjct: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIAFVHGSPRAGDLGFAGTMTLSFCGH 420 Query: 421 QENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHP 480 QENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHP Sbjct: 421 QENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHP 480 Query: 481 AVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEF 540 AVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEF Sbjct: 481 AVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEF 540 Query: 541 VLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 571 VLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ Sbjct: 541 VLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 571 >gi|157311624 acyl-CoA synthetase medium-chain family member 2B [Homo sapiens] Length = 577 Score = 1103 bits (2852), Expect = 0.0 Identities = 550/577 (95%), Positives = 553/577 (95%), Gaps = 6/577 (1%) Query: 1 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA Sbjct: 1 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60 Query: 61 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWW 120 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAAN+LSGACGLQRGDRVAVMLPRVPEWW Sbjct: 61 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWW 120 Query: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK Sbjct: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180 Query: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL Sbjct: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240 Query: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL Sbjct: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300 Query: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF Sbjct: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360 Query: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI---AFVHGSPRAGDLGFAGTMTLS- 416 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI V GD+G Sbjct: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIDDKGNVLPPGTEGDIGIRVKPIRPI 420 Query: 417 --FCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 474 F G+ ENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN Sbjct: 421 GIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 480 Query: 475 ALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKY 534 ALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKY Sbjct: 481 ALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKY 540 Query: 535 PRKIEFVLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 571 PRKIEFVLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ Sbjct: 541 PRKIEFVLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 577 >gi|157311622 acyl-CoA synthetase medium-chain family member 2B [Homo sapiens] Length = 577 Score = 1103 bits (2852), Expect = 0.0 Identities = 550/577 (95%), Positives = 553/577 (95%), Gaps = 6/577 (1%) Query: 1 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA Sbjct: 1 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60 Query: 61 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWW 120 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAAN+LSGACGLQRGDRVAVMLPRVPEWW Sbjct: 61 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWW 120 Query: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK Sbjct: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180 Query: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL Sbjct: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240 Query: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL Sbjct: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300 Query: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF Sbjct: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360 Query: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI---AFVHGSPRAGDLGFAGTMTLS- 416 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI V GD+G Sbjct: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIDDKGNVLPPGTEGDIGIRVKPIRPI 420 Query: 417 --FCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 474 F G+ ENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN Sbjct: 421 GIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 480 Query: 475 ALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKY 534 ALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKY Sbjct: 481 ALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKY 540 Query: 535 PRKIEFVLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 571 PRKIEFVLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ Sbjct: 541 PRKIEFVLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 577 >gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo sapiens] Length = 577 Score = 1079 bits (2790), Expect = 0.0 Identities = 537/577 (93%), Positives = 546/577 (94%), Gaps = 6/577 (1%) Query: 1 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA Sbjct: 1 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60 Query: 61 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWW 120 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAV+LPRVPEWW Sbjct: 61 GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWW 120 Query: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK Sbjct: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180 Query: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL Sbjct: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240 Query: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300 KAKMDAGWTGLQASDIMWTISDTGWILNIL SL+E W LGACTFVHLLPKFDPLVILKTL Sbjct: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTL 300 Query: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNC+ GESLLPETLENWRAQTGLDIRE Sbjct: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRES 360 Query: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI---AFVHGSPRAGDLGFAGTMTLS- 416 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQ+I V GD+G Sbjct: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPI 420 Query: 417 --FCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 474 F G+ +NPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN Sbjct: 421 GIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 480 Query: 475 ALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKY 534 ALM+HPAVVETAVISSPDPVRGEVVKAFV+LASQFLSHDPEQLTKELQQHVKSVTAPYKY Sbjct: 481 ALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKY 540 Query: 535 PRKIEFVLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 571 PRKIEFVLNLPKTVTGKIQR KLRDKEWKMSGKARAQ Sbjct: 541 PRKIEFVLNLPKTVTGKIQRAKLRDKEWKMSGKARAQ 577 >gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo sapiens] Length = 580 Score = 637 bits (1642), Expect = 0.0 Identities = 311/534 (58%), Positives = 393/534 (73%), Gaps = 7/534 (1%) Query: 37 HQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANV 96 ++ +P FNFA+DVLD W+ EK G+R +PALWWVNGKG E+ W+FREL S++AANV Sbjct: 45 NRPLPKNFNFAADVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFRELGSLSRKAANV 104 Query: 97 LSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKA 156 L+ CGLQRGDR+AV+LPR+PEWWLV + CIR G+IFMPGTIQ+ + DILYRL+ SKAK Sbjct: 105 LTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKC 164 Query: 157 IVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEAS 216 IVA +EV V+++ ECP L+ KLLVS +S +GWL+F++L AS H CVETGSQE Sbjct: 165 IVASEEVAPAVESIVLECPDLKTKLLVSPQSWNGWLSFQELFQFASEEHSCVETGSQEPM 224 Query: 217 AIYFTSGTSGLPKMAEHSYSSLGLKAKM-DAGWTGLQASDIMWTISDTGWILNILGSLLE 275 IYFTSGT+G PKMA+HS SSLG+ + W L++SDI+W +SDTGW+ +GS+ Sbjct: 225 TIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFS 284 Query: 276 SWTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCL 335 SW GAC FVH + +FD L TL++YPI ++ P VYRML+Q+DL YKF L++CL Sbjct: 285 SWLCGACVFVHRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQKDLKRYKFKSLRHCL 344 Query: 336 AGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI 395 GGE L PE LE WR QTGL++ E YGQTE G+ C K +IKPG MG YDVQ+I Sbjct: 345 TGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPYDVQII 404 Query: 396 ---AFVHGSPRAGDLGFAGTMTLSFC---GHQENPDKTAANIRGDFWLLGDRGIKDEDGY 449 V + G++ T FC + +NP KTAA IRGDF++ GDRG+ D DGY Sbjct: 405 DENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYVTGDRGVMDSDGY 464 Query: 450 FQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQF 509 F F+GRADD+I SSGYRIGP EVE+AL++HPAVVE+AV+SSPD +RGEVVKAFV+LA+ F Sbjct: 465 FWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPF 524 Query: 510 LSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEWK 563 S++PE+LT ELQ HVK TAPYKYPRK+EFV LPKT+TGKI+R LRD+EW+ Sbjct: 525 KSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWR 578 >gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo sapiens] Length = 577 Score = 609 bits (1571), Expect = e-174 Identities = 305/578 (52%), Positives = 405/578 (70%), Gaps = 22/578 (3%) Query: 1 MHWLRKVQGLCTLWGTQMSSRTLYINSRQLV--------SLQWGHQEVPAKFNFASDVLD 52 M WL + + TLWG S ++ QL + +W EVP +FNFAS VLD Sbjct: 1 MQWLMRFR---TLWGIHKSFHNIHPAPSQLRCRSLSEFGAPRWNDYEVPEEFNFASYVLD 57 Query: 53 HWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVM 112 +WA EK GKR P+PA WWVNG+G E+ W+FRE+ + +++ ANV + CGLQ+GD +A+M Sbjct: 58 YWAQKEKEGKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDHLALM 117 Query: 113 LPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVAS 172 LPRVPEWWLV +GC+R G+IF+P TI +K+ DILYRLQ+SKAK IV D + EVD++AS Sbjct: 118 LPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVTIDALASEVDSIAS 177 Query: 173 ECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAE 232 +CPSL+ KLLVS+ S +GWL+F+ L+ AS H CV++ + + I+FTSGT+G PKMA+ Sbjct: 178 QCPSLKTKLLVSDHSREGWLDFRSLVKSASPEHTCVKSKTLDPMVIFFTSGTTGFPKMAK 237 Query: 233 HSYSSLGLKAKMDAG--WTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPK 290 HS+ L L+ L+ SD+ W +SD+GWI+ + +L+E WT G F+H LP+ Sbjct: 238 HSH-GLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVEPWTAGCTVFIHHLPQ 296 Query: 291 FDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWR 350 FD VI++TL YPI G +YRM+LQQD +S +FP L++C GGE +LP+ E W+ Sbjct: 297 FDTKVIIQTLLKYPINHFWGVSSIYRMILQQDFTSIRFPALEHCYTGGEVVLPKDQEEWK 356 Query: 351 AQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI---AFVHGSPRAGDL 407 +TGL + E YGQ+ETGL C MKIKPG+MG A YDVQVI + G++ Sbjct: 357 RRTGLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVIDDKGSILPPNTEGNI 416 Query: 408 GF----AGTMTLSFCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSS 463 G ++L C ++ +P+KTA GDF+ GDRG DE+GY F+GR+DDIIN+S Sbjct: 417 GIRIKPVRPVSLFMC-YEGDPEKTAKVECGDFYNTGDRGKMDEEGYICFLGRSDDIINAS 475 Query: 464 GYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQ 523 GYRIGP+EVE+AL++HPAV E+AV+ SPDP+RGEVVKAF++L QFLSHD +QLTKELQQ Sbjct: 476 GYRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTPQFLSHDKDQLTKELQQ 535 Query: 524 HVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKE 561 HVKSVTAPYKYPRK+EFV LPKT+TGKI+R +LR KE Sbjct: 536 HVKSVTAPYKYPRKVEFVSELPKTITGKIERKELRKKE 573 >gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo sapiens] Length = 579 Score = 597 bits (1538), Expect = e-170 Identities = 290/538 (53%), Positives = 382/538 (71%), Gaps = 8/538 (1%) Query: 32 SLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQ 91 ++ G Q VP FNFA DVLD W+ +E+AG R P+PA WWVNG G E+ W+F EL + S+ Sbjct: 41 AISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSR 100 Query: 92 QAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQM 151 +AANVL GACGLQ GDR+ ++LPR+PEWWLV + C+R G + +PG Q+ D+ YRLQ Sbjct: 101 KAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQA 160 Query: 152 SKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETG 211 S+AK+I+ D + VD +++ECPSL+ KLLVS+ S GWLNF++LL EAST H+C+ T Sbjct: 161 SRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTK 220 Query: 212 SQEASAIYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNIL 270 S++ AIYFTSGT+G PKM EHS SS GL W L SDI W +DTGW+ Sbjct: 221 SRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWV-KAA 279 Query: 271 GSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPH 330 +L +W G+C FVH LP+ D VIL TLS +PI ++ P ++R+L+Q+DL+ Y+F Sbjct: 280 WTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQS 339 Query: 331 LQNCLAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCY 390 L++CL GGE+L P+ E W+ QTG+++ E YGQ+ET + C K MKIK G MG A+ Y Sbjct: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399 Query: 391 DVQVI---AFVHGSPRAGDLGFAGTMTLSFC---GHQENPDKTAANIRGDFWLLGDRGIK 444 DVQ++ V G++ T FC + +NP+KTAA+ +GDF++ GDR Sbjct: 400 DVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARM 459 Query: 445 DEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504 D+DGYF FMGR DD+INSS YRIGP EVE+AL +HPAV+E+AV+SSPDP+RGEVVKAF++ Sbjct: 460 DKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIV 519 Query: 505 LASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEW 562 L + SHDPE LT+ELQ+HVK VTAPYKYPRK+ FV LPKTV+GKIQR+KLR +EW Sbjct: 520 LTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEW 577 >gi|42544132 SA hypertension-associated homolog isoform 1 [Homo sapiens] Length = 586 Score = 592 bits (1526), Expect = e-169 Identities = 286/531 (53%), Positives = 364/531 (68%), Gaps = 7/531 (1%) Query: 40 VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSG 99 +P FNFA DVLD W D EKAGK+ +PA WW+N G+E+ W+F EL S++ AN+LS Sbjct: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113 Query: 100 ACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159 AC LQRGDRV ++LPRVPEWWL + C+R G + +PGT Q+ DILYRLQ SKA I+ Sbjct: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173 Query: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219 D + VD VAS+C +L KL+VSE S +GW N K+L+ AS +H CV+T E AI+ Sbjct: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233 Query: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILGSLLESWT 278 FTSGTSG PKM H++SS GL ++ W L SD+MW SDTGW + S+ W Sbjct: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293 Query: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGG 338 GAC F H LP+F+P IL+TLS YPI AP VYRML+Q D++SYKF L++C++ G Sbjct: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353 Query: 339 ESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIAFV 398 E + P+ E WR +TGLDI E YGQTET L C K MKIKPG MG + +DV+++ Sbjct: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN 413 Query: 399 HGSPRAGDLGFAGTMTLS------FCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQF 452 G G G L F + +NP KTA+ +RG+F++ GDRG D+DGYF F Sbjct: 414 GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWF 473 Query: 453 MGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSH 512 + RADD+I SSGYRIGP EVENAL +HP+V E+AV+SSPDP+RGEVVKAFV+L + SH Sbjct: 474 VARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSH 533 Query: 513 DPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEWK 563 D EQL KE+Q+HVK TAPYKYPRK+EF+ LPKT++GK +R +LR KEWK Sbjct: 534 DQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWK 584 >gi|42544134 SA hypertension-associated homolog isoform 2 [Homo sapiens] Length = 438 Score = 394 bits (1012), Expect = e-109 Identities = 188/356 (52%), Positives = 239/356 (67%), Gaps = 1/356 (0%) Query: 40 VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSG 99 +P FNFA DVLD W D EKAGK+ +PA WW+N G+E+ W+F EL S++ AN+LS Sbjct: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113 Query: 100 ACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159 AC LQRGDRV ++LPRVPEWWL + C+R G + +PGT Q+ DILYRLQ SKA I+ Sbjct: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173 Query: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219 D + VD VAS+C +L KL+VSE S +GW N K+L+ AS +H CV+T E AI+ Sbjct: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233 Query: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILGSLLESWT 278 FTSGTSG PKM H++SS GL ++ W L SD+MW SDTGW + S+ W Sbjct: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293 Query: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGG 338 GAC F H LP+F+P IL+TLS YPI AP VYRML+Q D++SYKF L++C++ G Sbjct: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353 Query: 339 ESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQV 394 E + P+ E WR +TGLDI E YGQTET L C K MKIKPG MG + +DV+V Sbjct: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409 >gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo sapiens] Length = 480 Score = 344 bits (882), Expect = 1e-94 Identities = 182/438 (41%), Positives = 268/438 (61%), Gaps = 8/438 (1%) Query: 38 QEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVL 97 Q V FNFA DVLD W+ +EK G R P PALW V+ KG+E W+F +++ S++AA++L Sbjct: 43 QAVSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASIL 102 Query: 98 SGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAI 157 S C L GDR+ ++LP PE + + L C+R G+ F+PG+ Q+ + I Y+L+MSKA+ I Sbjct: 103 SDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCI 162 Query: 158 VAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASA 217 VA + + V++ S+CP+L+ KLLVS+KS DGWL+FKKL+ A + T SQ+ A Sbjct: 163 VANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMA 222 Query: 218 IYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNILGSLLES 276 I+FT GT+G PKM E+S LG+ ++ W LQ +D++W++ D L ++L + Sbjct: 223 IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGT 282 Query: 277 WTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQD-LSSYKFPHLQNCL 335 W GAC F+ +P F P +L LS +PI ++ P +Y+ LLQ +SY+F L+ C+ Sbjct: 283 WFQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCV 342 Query: 336 AGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI 395 A G + P +E+W+ T LDI E YGQTETGL C SKT+K+KP +G Y VQ++ Sbjct: 343 AAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIV 402 Query: 396 AFVHGSPRAGDLG-FAGTMTLS-----FCGHQENPDKTAANIRGDFWLLGDRGIKDEDGY 449 G+ G A + L+ +C H + ++ A+ +L GDRGI DEDGY Sbjct: 403 DENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGY 462 Query: 450 FQFMGRADDIINSSGYRI 467 F + GR DD+ N+ G R+ Sbjct: 463 FWWSGRVDDVANALGQRL 480 >gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo sapiens] Length = 689 Score = 155 bits (392), Expect = 9e-38 Identities = 149/535 (27%), Positives = 234/535 (43%), Gaps = 59/535 (11%) Query: 69 LWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIR 128 +W + G E+ +REL E + + AN L G+ RGDRVA+ +P P +L C R Sbjct: 129 IWERDEPGTEVRITYRELLETTCRLANTLKRH-GVHRGDRVAIYMPVSPLAVAAMLACAR 187 Query: 129 AGLIFMPGTIQMKSTDILYRLQMSKAKAIVA------GDEVIQE---VDTVASECPSLRI 179 G + + + R+ +K K ++ G V++ VD CP+++ Sbjct: 188 IGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQH 247 Query: 180 KLLV---SEKSCDGWLNFKKLLNEASTTHHCV--ETGSQEASAIYFTSGTSGLPKMAEHS 234 L+ K G L+ A C GS++ + +TSG++G+PK H+ Sbjct: 248 VLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHT 307 Query: 235 ------YSSLGLKAKMDAGWTGLQASDIMWTISDTGWILN----ILGSLLESWTLGACTF 284 Y++L K D Q DI ++D GWI + G L T Sbjct: 308 QAGYLLYAALTHKLVFDH-----QPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFES 362 Query: 285 VHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQD---LSSYKFPHLQNCLAGGESL 341 + P +T+ I GAP R+LL+ + Y L+ + GE + Sbjct: 363 TPVYPNAGRY--WETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPI 420 Query: 342 LPETLENWRAQTGLDIR----EFYGQTETGLTCMVSK----------TMKIKPGYMGTAA 387 E E W + D R + + QTETG C+ + M ++P + G Sbjct: 421 NCEAWE-WLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEILPAMAMRP-FFGIVP 478 Query: 388 SCYDVQVIAFVHGSPRAGDL----GFAGTMTLSFCGHQENPDKTAANIRGDFWLLGDRGI 443 D + + V GS +G L + G + HQ D G ++ GD Sbjct: 479 VLMDEKG-SVVEGSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKAYPG-YYFTGDGAY 536 Query: 444 KDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFV 503 + E GY+Q GR DD+IN SG+R+G +E+E+A+ HPAV E+AVI P ++GE AF+ Sbjct: 537 RTEGGYYQITGRMDDVINISGHRLGTAEIEDAIADHPAVPESAVIGYPHDIKGEAAFAFI 596 Query: 504 ILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 558 ++ + D + + +EL+ V + A Y P +I V LPKT +GK+ R LR Sbjct: 597 VVKDS--AGDSDVVVQELKSMVATKIAKYAVPDEILVVKRLPKTRSGKVMRRLLR 649 >gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo sapiens] Length = 686 Score = 139 bits (351), Expect = 5e-33 Identities = 133/519 (25%), Positives = 220/519 (42%), Gaps = 49/519 (9%) Query: 81 WNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQM 140 + ++E+ E + A VL G+++GD V + +P +P+ +L C R G I Sbjct: 144 FTYKEVLEQVSKLAGVLVKH-GIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGF 202 Query: 141 KSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNE 200 S ++ R+ K K +V I+ V P + L + + D L + + E Sbjct: 203 ASKELSSRIDHVKPKVVVTASFGIEPGRRV-EYVPLVEEALKIGQHKPDKILIYNRPNME 261 Query: 201 A-----------------STTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAK 243 A + +H CV S+ I +TSGT+GLPK + Sbjct: 262 AVPLAPGRDLDWDEEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKGVIRPTGGYAVMLH 321 Query: 244 MD-AGWTGLQASDIMWTISDTGWILN----ILGSLLESWTLGACTFVHL---LPKFDPLV 295 + GLQ ++ W SD GW++ G LL G T ++ + D Sbjct: 322 WSMSSIYGLQPGEVWWAASDLGWVVGHSYICYGPLLH----GNTTVLYEGKPVGTPDAGA 377 Query: 296 ILKTLSSYPIKSMMGAPIVYRMLLQQDLSS-----YKFPHLQNCLAGGESLLPETLENWR 350 + L+ + + ++ AP R + QQD + Y + GE ETLE + Sbjct: 378 YFRVLAEHGVAALFTAPTAIRAIRQQDPGAALGKQYSLTRFKTLFVAGERCDVETLEWSK 437 Query: 351 AQTGLDIREFYGQTETG----LTCM-VSKTMKIKPGYMGTAASCYDVQVIAFVHGSPRAG 405 + + + + QTETG +C+ + + PG G + Y+V ++ +A Sbjct: 438 NVFRVPVLDHWWQTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKLKAR 497 Query: 406 DLG-FAGTMTL---SFCGHQENPDKTAANIRGDF---WLLGDRGIKDEDGYFQFMGRADD 458 LG + L +F G +N + F + D G DE+GY M R DD Sbjct: 498 CLGNIVVKLPLPPGAFSGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSRVDD 557 Query: 459 IINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLT 518 +IN +G+RI +E +++ H V + AV+ DP++G V A +L ++ EQ+ Sbjct: 558 VINVAGHRISAGAIEESILSHGTVADCAVVGKEDPLKGHVPLALCVLRKD-INATEEQVL 616 Query: 519 KELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557 +E+ +HV+ P R FV LPKT +GKI R+ L Sbjct: 617 EEIVKHVRQNIGPVAAFRNAVFVKQLPKTRSGKIPRSAL 655 >gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform 1 [Homo sapiens] Length = 701 Score = 136 bits (343), Expect = 5e-32 Identities = 148/591 (25%), Positives = 240/591 (40%), Gaps = 95/591 (16%) Query: 42 AKFNFASDVLDHWADMEKAGKRLPSPALWWV-NGKGKELMWNFRELSENSQQAANVLSGA 100 A N +VLD +K G ++ A +W N G+ + +L Q +NVL Sbjct: 99 ATTNICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ 155 Query: 101 CGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA- 159 G+Q+GDRVA+ +P +PE + +L C R G + S + R+ S ++ Sbjct: 156 -GIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITT 214 Query: 160 ---------------GDEVIQEVDT------------------------------VASEC 174 DE +Q+ + C Sbjct: 215 DAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSC 274 Query: 175 PSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHS 234 P ++I + D W + +L+ EA +++ I +TSG++G PK H+ Sbjct: 275 PDVQISW---NQGIDLW--WHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHT 329 Query: 235 YSSLGLKAKMDAGWT-GLQASDIMWTISDTGWILN----ILGSLLESWTLGACTFVHLLP 289 L + A D+ W +D GWI G L T + P Sbjct: 330 VGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYP 389 Query: 290 KFDPLVILKTLSSYPIKSMMGAPIVYRMLLQ---QDLSSYKFPHLQNCLAGGESLLPETL 346 + L + + Y + AP R+L++ + ++ + LQ GE + PE Sbjct: 390 DVNRLWSI--VDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAW 447 Query: 347 ENWRAQTGLD---IREFYGQTETG---LTCMVSKTMKIKPG-----YMGTAASCYDVQVI 395 + G I + + QTETG LT + T +KPG + G A + + Sbjct: 448 LWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGAT-PMKPGSATFPFFGVAPAILNES-- 504 Query: 396 AFVHGSPRAGDLG--------FAGTMTLSFCGHQENPDKTAANIRGDFWLLGDRGIKDED 447 G G+ + G M + G+ E + T +++ GD +D+D Sbjct: 505 ----GEELEGEAEGYLVFKQPWPGIMRTVY-GNHERFETTYFKKFPGYYVTGDGCQRDQD 559 Query: 448 GYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILAS 507 GY+ GR DD++N SG+ + +EVE+AL++H AV E AV+ P PV+GE + FV L Sbjct: 560 GYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCD 619 Query: 508 QFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 558 + P +LT+EL++ ++ P P I+ LPKT +GKI R LR Sbjct: 620 GH-TFSP-KLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 668 >gi|253970489 acyl-CoA synthetase short-chain family member 2 isoform 2 [Homo sapiens] Length = 714 Score = 135 bits (340), Expect = 1e-31 Identities = 148/599 (24%), Positives = 241/599 (40%), Gaps = 98/599 (16%) Query: 42 AKFNFASDVLDHWADMEKAGKRLPSPALWWV-NGKGKELMWNFRELSENSQQAANVLSGA 100 A N +VLD +K G ++ A +W N G+ + +L Q +NVL Sbjct: 99 ATTNICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ 155 Query: 101 CGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA- 159 G+Q+GDRVA+ +P +PE + +L C R G + S + R+ S ++ Sbjct: 156 -GIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITT 214 Query: 160 ---------------GDEVIQEVDT------------------------------VASEC 174 DE +Q+ + C Sbjct: 215 DAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSC 274 Query: 175 PSLRIKLLVSEKSCDGWLNFKK--------LLNEASTTHHCVETGSQEASAIYFTSGTSG 226 P ++ KL K +++ + L+ EA +++ I +TSG++G Sbjct: 275 PDVQGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTG 334 Query: 227 LPKMAEHSYSSLGLKAKMDAGWT-GLQASDIMWTISDTGWILN----ILGSLLESWTLGA 281 PK H+ L + A D+ W +D GWI G L T Sbjct: 335 KPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVL 394 Query: 282 CTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQ---QDLSSYKFPHLQNCLAGG 338 + P + L + + Y + AP R+L++ + ++ + LQ G Sbjct: 395 FEGIPTYPDVNRLWSI--VDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVG 452 Query: 339 ESLLPETLENWRAQTGLD---IREFYGQTETG---LTCMVSKTMKIKPG-----YMGTAA 387 E + PE + G I + + QTETG LT + T +KPG + G A Sbjct: 453 EPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGAT-PMKPGSATFPFFGVAP 511 Query: 388 SCYDVQVIAFVHGSPRAGDLG--------FAGTMTLSFCGHQENPDKTAANIRGDFWLLG 439 + + G G+ + G M + G+ E + T +++ G Sbjct: 512 AILNES------GEELEGEAEGYLVFKQPWPGIMRTVY-GNHERFETTYFKKFPGYYVTG 564 Query: 440 DRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVV 499 D +D+DGY+ GR DD++N SG+ + +EVE+AL++H AV E AV+ P PV+GE + Sbjct: 565 DGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECL 624 Query: 500 KAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 558 FV L + P +LT+EL++ ++ P P I+ LPKT +GKI R LR Sbjct: 625 YCFVTLCDGH-TFSP-KLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 681 >gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] Length = 576 Score = 109 bits (273), Expect = 6e-24 Identities = 125/526 (23%), Positives = 217/526 (41%), Gaps = 75/526 (14%) Query: 83 FRELSENSQQAANVLSGACGLQRGD----RVAVMLPRVPEWWLVILGCIRAGLIFMPGTI 138 +REL S + + + CG GD RV+ + + + +G + +P Sbjct: 68 YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127 Query: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198 + + + Y + S++ ++A E ++ + V + L + LL + + + Sbjct: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179 Query: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253 E + + + + I +TSGT+G PK ++ ++ GL K WT Sbjct: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234 Query: 254 SDIMWTISDTGWILNILGSLL-ESWTLGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMM 309 D++ + + ++ +LL W C ++P+F P + K LSS I M Sbjct: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV---MMPEFSPQQVWEKFLSSETPRINVFM 291 Query: 310 GAPIVYRMLLQQDLSSYKFPHLQNCL-----------AGGESLLP-ETLENWRAQTGLDI 357 P +Y L++ + PH Q+ L G + LP LE W+ TG + Sbjct: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351 Query: 358 REFYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQVIA----------FVHG------ 400 E YG TE G+ T ++ PG +GT V++++ +H Sbjct: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411 Query: 401 -------SPRAGDLGFAGTMTLSFCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFM 453 + G+L G F + P++T + D W + +DG + Sbjct: 412 TKVTPGFEEKEGELLVRGPSV--FREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIR 469 Query: 454 GRAD-DIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVIL-ASQFLS 511 GR DII + GY++ EVE L+ HP++ + AVI PD G+ V A V L LS Sbjct: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529 Query: 512 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557 H +EL++ ++V APY P ++ V +P+ GKI + L Sbjct: 530 H------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569 >gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] Length = 576 Score = 109 bits (273), Expect = 6e-24 Identities = 125/526 (23%), Positives = 217/526 (41%), Gaps = 75/526 (14%) Query: 83 FRELSENSQQAANVLSGACGLQRGD----RVAVMLPRVPEWWLVILGCIRAGLIFMPGTI 138 +REL S + + + CG GD RV+ + + + +G + +P Sbjct: 68 YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127 Query: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198 + + + Y + S++ ++A E ++ + V + L + LL + + + Sbjct: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179 Query: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253 E + + + + I +TSGT+G PK ++ ++ GL K WT Sbjct: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234 Query: 254 SDIMWTISDTGWILNILGSLL-ESWTLGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMM 309 D++ + + ++ +LL W C ++P+F P + K LSS I M Sbjct: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV---MMPEFSPQQVWEKFLSSETPRINVFM 291 Query: 310 GAPIVYRMLLQQDLSSYKFPHLQNCL-----------AGGESLLP-ETLENWRAQTGLDI 357 P +Y L++ + PH Q+ L G + LP LE W+ TG + Sbjct: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351 Query: 358 REFYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQVIA----------FVHG------ 400 E YG TE G+ T ++ PG +GT V++++ +H Sbjct: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411 Query: 401 -------SPRAGDLGFAGTMTLSFCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFM 453 + G+L G F + P++T + D W + +DG + Sbjct: 412 TKVTPGFEEKEGELLVRGPSV--FREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIR 469 Query: 454 GRAD-DIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVIL-ASQFLS 511 GR DII + GY++ EVE L+ HP++ + AVI PD G+ V A V L LS Sbjct: 470 GRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLS 529 Query: 512 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557 H +EL++ ++V APY P ++ V +P+ GKI + L Sbjct: 530 H------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569 >gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] Length = 615 Score = 107 bits (266), Expect = 4e-23 Identities = 137/528 (25%), Positives = 227/528 (42%), Gaps = 59/528 (11%) Query: 77 KELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPG 136 +++ F +L E +AA+ L + GL +GDR+ + P W L+ L +AG+I + Sbjct: 96 EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154 Query: 137 TIQMKSTDILYRLQMSKAKAIVAGDE--VIQEVDTVASECP-----------SLRIKLLV 183 ++ ++ Y L+ KA+V + Q + + CP S R+ L Sbjct: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214 Query: 184 SEKSCDGWLNFKKLLNEA----STTHHC--VETGSQEASA-----IYFTSGTSGLPKMAE 232 + S D L LL+E ST H ++ Q S I FTSGT+G PK A Sbjct: 215 TVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGAT 274 Query: 233 HSYSS-------LGLKAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWT--LGACT 283 S+ + LG + K+ T Q I+ + + LGS+ + + T Sbjct: 275 LSHYNIVNNSNILGERLKLHEK-TPEQLRMIL-----PNPLYHCLGSVAGTMMCLMYGAT 328 Query: 284 FVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQ-DLSSYKFPHLQNCLAGGESLL 342 + P F+ L+ +S + G P ++ +L Q D SSY + + G Sbjct: 329 LILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAP 388 Query: 343 PETLENWRAQTGL-DIREFYGQTETGLTCMV---SKTMKIKPGYMGTAASCYDVQVIAFV 398 PE + + + D+ YG TE T++ K +G + +++ Sbjct: 389 PELIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNME 448 Query: 399 HGSPRAGDLGFAGTMTL-SFC---GHQENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFM 453 G+ L G + + +C G+ P KT + D W GD +E G+ + + Sbjct: 449 AGT--LAKLNTPGELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIV 506 Query: 454 GRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHD 513 GR+ D+I G I P+E+E+ HP V E V+ D GE + A + L D Sbjct: 507 GRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL------KD 560 Query: 514 PEQLT-KELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDK 560 E+ T +E++ K + +K P+ I FV N P T++GKIQ+ KLR++ Sbjct: 561 GEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608 >gi|38524616 solute carrier family 27, member 1 [Homo sapiens] Length = 646 Score = 91.7 bits (226), Expect = 2e-18 Identities = 134/519 (25%), Positives = 204/519 (39%), Gaps = 58/519 (11%) Query: 81 WNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQM 140 W F +L S AN+ G GD VA+ L PE+ + LG +AG+ + + Sbjct: 104 WTFAQLDAYSNAVANLFR-QLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162 Query: 141 KSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLN----FKK 196 + + + L S AKA++ G E++ V V+ IK + +G L Sbjct: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222 Query: 197 LLNEASTT--HHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQAS 254 LL EAST G + +TSGT+GLPK A +S A +QA+ Sbjct: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAA 282 Query: 255 DIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMG 310 D+++ G I+ + L+ T V L KF Y + Sbjct: 283 DVLYDCLPLYHSAGNIIGVGQCLIYGLT------VVLRKKFSASRFWDDCIKYNCTVVQY 336 Query: 311 APIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGL-DIREFYGQTETGLT 369 + R LL+Q + + H LA G L P E + + G+ I EFYG TE Sbjct: 337 IGEICRYLLKQPVREAERRHRVR-LAVGNGLRPAIWEEFTERFGVRQIGEFYGATE--CN 393 Query: 370 CMVSKTMKIKPGYMG----TAASCYDVQVIAFVHGSP-------------RAGDLG-FAG 411 C ++ M K G G Y ++++ + +AG+ G G Sbjct: 394 CSIA-NMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG 452 Query: 412 TMTL--------SFCGHQENPDKTAANI--RGD-FWLLGDRGIKDEDGYFQFMGRADDII 460 + + K A ++ +GD +L GD + DE GY F R+ D Sbjct: 453 QINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTF 512 Query: 461 NSSGYRIGPSEVENALMKHPAVVETAVISSPDP-VRGEVVKAFVILASQFLSHDPEQLTK 519 G + +EVE L + + AV P V G+ A V L DP + + Sbjct: 513 RWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLL--DPNAIYQ 570 Query: 520 ELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 558 ELQ+ V APY P + + + T T KIQ+T+L+ Sbjct: 571 ELQK----VLAPYARPIFLRLLPQVDTTGTFKIQKTRLQ 605 >gi|40807357 solute carrier family 27 (fatty acid transporter), member 4 [Homo sapiens] Length = 643 Score = 70.9 bits (172), Expect = 3e-12 Identities = 133/533 (24%), Positives = 202/533 (37%), Gaps = 75/533 (14%) Query: 75 KGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFM 134 +G + W FR+L E S AN L A GL GD A+ + E+ + LG + G+ Sbjct: 96 EGTDTHWTFRQLDEYSSSVANFLQ-ARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAA 154 Query: 135 PGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTV-ASECPSLRIKLLVSEKSCDG-WL 192 ++ +L+ L S+A+A+V G E+ + V AS PSL + C G W Sbjct: 155 LINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSL-------FCSGSWE 207 Query: 193 ---------NFKKLLNEAST-THHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKA 242 + LL +A C + G + +TSGT+GLPK A +S A Sbjct: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267 Query: 243 KMDAGWTGLQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILK 298 + ++ +DI++ G I+ I LL T V + KF Sbjct: 268 ALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMT------VVIRKKFSASRFWD 321 Query: 299 TLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGL-DI 357 Y + + R LL Q + H Q +A G L N+ ++ + + Sbjct: 322 DCIKYNCTIVQYIGELCRYLLNQPPREAENQH-QVRMALGNGLRQSIWTNFSSRFHIPQV 380 Query: 358 REFYGQTETG---------------------------LTCMVSKTMKIKPGYMGTAASCY 390 EFYG TE L + TM++ G G C Sbjct: 381 AEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQ 440 Query: 391 DVQVIAFVHGSPRAGDL-GFAGTMTLSFCGHQENPDKTAANI--RGD-FWLLGDRGIKDE 446 + V + L F G + N K A ++ +GD +L GD + DE Sbjct: 441 PGEPGQLVGRIIQKDPLRRFDG-----YLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDE 495 Query: 447 DGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDP-VRGEVVKAFVIL 505 GY F R D G + +EVE L + + + AV P G A V Sbjct: 496 LGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAV-- 553 Query: 506 ASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 558 AS + D E+ + L++ + Y P + + L KT T K Q+T+LR Sbjct: 554 ASPTGNCDLERFAQVLEKELPL----YARPIFLRLLPELHKTGTYKFQKTELR 602 >gi|13236579 solute carrier family 27 member 3 [Homo sapiens] Length = 730 Score = 64.3 bits (155), Expect = 3e-10 Identities = 123/510 (24%), Positives = 194/510 (38%), Gaps = 61/510 (11%) Query: 93 AANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGL--IFMPGTIQMKSTDILYRLQ 150 AA A L G VA++LP PE+ + G +AGL F+P + + +L+ L+ Sbjct: 201 AARGGGAAAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTAL--RRGPLLHCLR 258 Query: 151 MSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGW--LNFKKLLNEASTTHHCV 208 A+A+V E ++ ++ + P+LR L + G LL E S Sbjct: 259 SCGARALVLAPEFLESLEP---DLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGP 315 Query: 209 ETG------SQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTIS 261 G S + +Y FTSGT+GLPK A S+ + L+ + G+ D+++ Sbjct: 316 VPGYLSSPQSITDTCLYIFTSGTTGLPKAARISHLKI-LQCQGFYQLCGVHQEDVIYLAL 374 Query: 262 D----TGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRM 317 +G +L I+G +G V L KF + + + + R Sbjct: 375 PLYHMSGSLLGIVG------CMGIGATVVLKSKFSAGQFWEDCQQHRVTVFQYIGELCRY 428 Query: 318 LLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE--------TGL 368 L+ Q S + H LA G L P+T E + + G L + E YG TE TG Sbjct: 429 LVNQPPSKAERGHKVR-LAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQ 487 Query: 369 TCMVSKTMKIKPGYMGTAASCYDV---QVIAFVHGSPRAGDLGFAGTMTL------SFCG 419 V + + + YDV + I G A G G + F G Sbjct: 488 RGAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLVAPVSQQSPFLG 547 Query: 420 HQENPDKTAANIRGD-------FWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEV 472 + P+ + D F+ GD + D+ G+ +F R D G + +EV Sbjct: 548 YAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEV 607 Query: 473 ENALMKHPAVVETAVISSPDP-VRGEVVKAFVILASQFLSHDPEQL-TKELQQHVKSVTA 530 + E V P G A ++L P L +L HV Sbjct: 608 AEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVL------RPPHALDLMQLYTHVSENLP 661 Query: 531 PYKYPRKIEFVLNLPKTVTGKIQRTKLRDK 560 PY PR + +L T T K Q+ ++ ++ Sbjct: 662 PYARPRFLRLQESLATTETFKQQKVRMANE 691 >gi|62865631 solute carrier family 27 (fatty acid transporter), member 6 [Homo sapiens] Length = 619 Score = 60.8 bits (146), Expect = 3e-09 Identities = 108/517 (20%), Positives = 207/517 (40%), Gaps = 57/517 (11%) Query: 80 MWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139 ++ ++++ + S + A+V L++GD VA+++ P++ V G + G + Sbjct: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138 Query: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196 ++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+ Sbjct: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195 Query: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250 L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G Sbjct: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252 Query: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306 A DI++ + IL I G + LGA L KF Y + Sbjct: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306 Query: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365 + R L +Q + H LA G + + + + G + + E Y TE Sbjct: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365 Query: 366 TGLTCMVSKTMKI----KPGYMGTAASCYDVQVIAFVHGSPRAGDLGF------------ 409 + ++ M + T +I + S +D+ F P + G+ Sbjct: 366 SSISFM-NYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424 Query: 410 -----AGTMTLSFCG-HQENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDII 460 A + G ++ DK ++ +GD +L GD ++D+D + F R D Sbjct: 425 ISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484 Query: 461 NSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 520 G + +EV + + + E V + G +A +AS L + ++ Sbjct: 485 RWKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEK 540 Query: 521 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557 + + V + Y PR + + T T K+ + +L Sbjct: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577 >gi|13325055 solute carrier family 27 (fatty acid transporter), member 6 [Homo sapiens] Length = 619 Score = 60.8 bits (146), Expect = 3e-09 Identities = 108/517 (20%), Positives = 207/517 (40%), Gaps = 57/517 (11%) Query: 80 MWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139 ++ ++++ + S + A+V L++GD VA+++ P++ V G + G + Sbjct: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138 Query: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196 ++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+ Sbjct: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195 Query: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250 L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G Sbjct: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252 Query: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306 A DI++ + IL I G + LGA L KF Y + Sbjct: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306 Query: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365 + R L +Q + H LA G + + + + G + + E Y TE Sbjct: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365 Query: 366 TGLTCMVSKTMKI----KPGYMGTAASCYDVQVIAFVHGSPRAGDLGF------------ 409 + ++ M + T +I + S +D+ F P + G+ Sbjct: 366 SSISFM-NYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424 Query: 410 -----AGTMTLSFCG-HQENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDII 460 A + G ++ DK ++ +GD +L GD ++D+D + F R D Sbjct: 425 ISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484 Query: 461 NSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 520 G + +EV + + + E V + G +A +AS L + ++ Sbjct: 485 RWKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEK 540 Query: 521 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557 + + V + Y PR + + T T K+ + +L Sbjct: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577 >gi|209529739 hypothetical protein LOC100132247 [Homo sapiens] Length = 1133 Score = 57.4 bits (137), Expect = 3e-08 Identities = 27/41 (65%), Positives = 32/41 (78%) Query: 498 VVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKI 538 +VK ++L QFLSHD QLTKELQQHVKSVT P +Y RK+ Sbjct: 1 MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRKV 41 >gi|239745501 PREDICTED: similar to acyl-CoA synthetase medium-chain family member 2 [Homo sapiens] Length = 1122 Score = 57.4 bits (137), Expect = 3e-08 Identities = 27/41 (65%), Positives = 32/41 (78%) Query: 498 VVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKI 538 +VK ++L QFLSHD QLTKELQQHVKSVT P +Y RK+ Sbjct: 1 MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRKV 41 >gi|239745482 PREDICTED: hypothetical protein [Homo sapiens] Length = 449 Score = 57.4 bits (137), Expect = 3e-08 Identities = 26/42 (61%), Positives = 32/42 (76%) Query: 497 EVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKI 538 ++VK ++L QFLSHD Q TKELQQHVKSVT P +Y RK+ Sbjct: 17 QMVKLSIVLTPQFLSHDQSQFTKELQQHVKSVTCPCEYLRKV 58 >gi|157074225 nuclear pore complex interacting protein-like 3 [Homo sapiens] Length = 678 Score = 57.4 bits (137), Expect = 3e-08 Identities = 27/41 (65%), Positives = 32/41 (78%) Query: 498 VVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKI 538 +VK ++L QFLSHD QLTKELQQHVKSVT P +Y RK+ Sbjct: 1 MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRKV 41 >gi|239745430 PREDICTED: hypothetical protein XP_002343465 [Homo sapiens] Length = 317 Score = 55.8 bits (133), Expect = 1e-07 Identities = 26/41 (63%), Positives = 32/41 (78%) Query: 498 VVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKI 538 +VK ++L +FLSHD QLTKELQQHVKSVT P +Y RK+ Sbjct: 1 MVKLSIVLTPRFLSHDQGQLTKELQQHVKSVTCPCEYLRKV 41 >gi|239745418 PREDICTED: similar to GPS, PLAT and transmembrane domain-containing protein FLJ00285 [Homo sapiens] Length = 317 Score = 55.8 bits (133), Expect = 1e-07 Identities = 26/41 (63%), Positives = 32/41 (78%) Query: 498 VVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKI 538 +VK ++L +FLSHD QLTKELQQHVKSVT P +Y RK+ Sbjct: 1 MVKLSIVLTPRFLSHDQGQLTKELQQHVKSVTCPCEYLRKV 41 >gi|239745416 PREDICTED: similar to GPS, PLAT and transmembrane domain-containing protein FLJ00285 [Homo sapiens] Length = 317 Score = 55.8 bits (133), Expect = 1e-07 Identities = 26/41 (63%), Positives = 32/41 (78%) Query: 498 VVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKI 538 +VK ++L +FLSHD QLTKELQQHVKSVT P +Y RK+ Sbjct: 1 MVKLSIVLTPRFLSHDQGQLTKELQQHVKSVTCPCEYLRKV 41 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.134 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,298,603 Number of Sequences: 37866 Number of extensions: 920772 Number of successful extensions: 2100 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 35 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 1987 Number of HSP's gapped (non-prelim): 81 length of query: 571 length of database: 18,247,518 effective HSP length: 108 effective length of query: 463 effective length of database: 14,157,990 effective search space: 6555149370 effective search space used: 6555149370 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.