Search of human proteins with 239755402

Search of human proteins with 239755402

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239755402 PREDICTED: hypothetical protein [Homo sapiens]
         (321 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755402 PREDICTED: hypothetical protein [Homo sapiens]           671   0.0  
gi|239749910 PREDICTED: hypothetical protein XP_002347211 [Homo ...   671   0.0  
gi|239744211 PREDICTED: hypothetical protein XP_002343075 [Homo ...   671   0.0  
gi|169211686 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-06
gi|169211670 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-06
gi|169210802 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-06
gi|239757829 PREDICTED: hypothetical protein [Homo sapiens]            49   8e-06
gi|239752340 PREDICTED: hypothetical protein XP_002348205 [Homo ...    49   8e-06
gi|239746853 PREDICTED: hypothetical protein XP_002343864 [Homo ...    49   8e-06
gi|221316609 sperm-associated cation channel 1 [Homo sapiens]          41   0.001
gi|4504487 histidine rich calcium binding protein precursor [Hom...    40   0.002
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              37   0.023
gi|4506885 semenogelin II precursor [Homo sapiens]                     36   0.040
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ...    36   0.052
gi|7657138 golgi integral membrane protein 4 [Homo sapiens]            36   0.052
gi|239752979 PREDICTED: hypothetical protein XP_002345320 [Homo ...    35   0.089
gi|239747560 PREDICTED: hypothetical protein XP_002347649 [Homo ...    35   0.089
gi|239741434 PREDICTED: hypothetical protein XP_002342199 [Homo ...    35   0.089
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    35   0.12 
gi|4501879 acrosomal vesicle protein 1 isoform a precursor [Homo...    34   0.15 
gi|60097902 filaggrin [Homo sapiens]                                   33   0.26 
gi|93141033 PAX interacting protein 1 [Homo sapiens]                   33   0.26 
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]        33   0.34 
gi|118766339 thyroid transcription factor 1 isoform 1 [Homo sapi...    33   0.34 
gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]     33   0.34 
gi|239755420 PREDICTED: hypothetical protein [Homo sapiens]            33   0.34 
gi|239749896 PREDICTED: hypothetical protein XP_002347199 isofor...    33   0.34 
gi|239749894 PREDICTED: hypothetical protein XP_002347198 isofor...    33   0.34 
gi|239744196 PREDICTED: hypothetical protein XP_002343054 [Homo ...    33   0.34 
gi|44890059 involucrin [Homo sapiens]                                  33   0.34 

>gi|239755402 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 321

 Score =  671 bits (1730), Expect = 0.0
 Identities = 321/321 (100%), Positives = 321/321 (100%)

Query: 1   MGGYLAGPSDQQFAQLLAEAVVQPGVDEGVVAGRTHGEPVAEQLHQPKGVRVDGVGVEVP 60
           MGGYLAGPSDQQFAQLLAEAVVQPGVDEGVVAGRTHGEPVAEQLHQPKGVRVDGVGVEVP
Sbjct: 1   MGGYLAGPSDQQFAQLLAEAVVQPGVDEGVVAGRTHGEPVAEQLHQPKGVRVDGVGVEVP 60

Query: 61  QQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELALALLGA 120
           QQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELALALLGA
Sbjct: 61  QQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELALALLGA 120

Query: 121 PELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHC 180
           PELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHC
Sbjct: 121 PELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHC 180

Query: 181 DGGEREHRHIDGDRLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV 240
           DGGEREHRHIDGDRLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV
Sbjct: 181 DGGEREHRHIDGDRLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV 240

Query: 241 RHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPV 300
           RHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPV
Sbjct: 241 RHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPV 300

Query: 301 ARRGLCALVGGSCDRRRQPRK 321
           ARRGLCALVGGSCDRRRQPRK
Sbjct: 301 ARRGLCALVGGSCDRRRQPRK 321


>gi|239749910 PREDICTED: hypothetical protein XP_002347211 [Homo
           sapiens]
          Length = 321

 Score =  671 bits (1730), Expect = 0.0
 Identities = 321/321 (100%), Positives = 321/321 (100%)

Query: 1   MGGYLAGPSDQQFAQLLAEAVVQPGVDEGVVAGRTHGEPVAEQLHQPKGVRVDGVGVEVP 60
           MGGYLAGPSDQQFAQLLAEAVVQPGVDEGVVAGRTHGEPVAEQLHQPKGVRVDGVGVEVP
Sbjct: 1   MGGYLAGPSDQQFAQLLAEAVVQPGVDEGVVAGRTHGEPVAEQLHQPKGVRVDGVGVEVP 60

Query: 61  QQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELALALLGA 120
           QQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELALALLGA
Sbjct: 61  QQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELALALLGA 120

Query: 121 PELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHC 180
           PELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHC
Sbjct: 121 PELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHC 180

Query: 181 DGGEREHRHIDGDRLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV 240
           DGGEREHRHIDGDRLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV
Sbjct: 181 DGGEREHRHIDGDRLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV 240

Query: 241 RHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPV 300
           RHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPV
Sbjct: 241 RHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPV 300

Query: 301 ARRGLCALVGGSCDRRRQPRK 321
           ARRGLCALVGGSCDRRRQPRK
Sbjct: 301 ARRGLCALVGGSCDRRRQPRK 321


>gi|239744211 PREDICTED: hypothetical protein XP_002343075 [Homo
           sapiens]
          Length = 321

 Score =  671 bits (1730), Expect = 0.0
 Identities = 321/321 (100%), Positives = 321/321 (100%)

Query: 1   MGGYLAGPSDQQFAQLLAEAVVQPGVDEGVVAGRTHGEPVAEQLHQPKGVRVDGVGVEVP 60
           MGGYLAGPSDQQFAQLLAEAVVQPGVDEGVVAGRTHGEPVAEQLHQPKGVRVDGVGVEVP
Sbjct: 1   MGGYLAGPSDQQFAQLLAEAVVQPGVDEGVVAGRTHGEPVAEQLHQPKGVRVDGVGVEVP 60

Query: 61  QQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELALALLGA 120
           QQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELALALLGA
Sbjct: 61  QQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELALALLGA 120

Query: 121 PELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHC 180
           PELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHC
Sbjct: 121 PELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHC 180

Query: 181 DGGEREHRHIDGDRLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV 240
           DGGEREHRHIDGDRLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV
Sbjct: 181 DGGEREHRHIDGDRLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV 240

Query: 241 RHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPV 300
           RHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPV
Sbjct: 241 RHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPV 300

Query: 301 ARRGLCALVGGSCDRRRQPRK 321
           ARRGLCALVGGSCDRRRQPRK
Sbjct: 301 ARRGLCALVGGSCDRRRQPRK 321


>gi|169211686 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 252

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 53/175 (30%), Positives = 73/175 (41%), Gaps = 27/175 (15%)

Query: 144 QRQHRGQRPDGQHSVGAEAQRDAP--PQRVHQHDVAVHC------DGGEREHRHIDGDRL 195
           Q   +G+ P+  +       RD    P+R     V+V C      DG  REH+H  G   
Sbjct: 94  QSDAKGKDPEDSNDPSCSGPRDQTFIPERDTDGQVSVDCHGQKAEDGALREHQHEAG--- 150

Query: 196 QEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV---RHVVQPAHPRDH 252
            EE+   + +AE  A   +G G  E      H HVG+ Q   E V      V+ AH   H
Sbjct: 151 -EEEAAVEVSAEAQADG-DGKGDGEE----PHGHVGRSQGHQEVVGGRLQSVRRAHRGAH 204

Query: 253 QHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPVARRGLCA 307
           QH   VA       D +++H Q +  + Q     GR  W+  A +R  A RG  A
Sbjct: 205 QH---VARHRKRGDDQLQRHVQRVLCLQQ----HGRASWAPGAPYRRRAGRGAAA 252


>gi|169211670 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 252

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 53/175 (30%), Positives = 73/175 (41%), Gaps = 27/175 (15%)

Query: 144 QRQHRGQRPDGQHSVGAEAQRDAP--PQRVHQHDVAVHC------DGGEREHRHIDGDRL 195
           Q   +G+ P+  +       RD    P+R     V+V C      DG  REH+H  G   
Sbjct: 94  QSDAKGKDPEDSNDPSCSGPRDQTFIPERDTDGQVSVDCHGQKAEDGALREHQHEAG--- 150

Query: 196 QEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV---RHVVQPAHPRDH 252
            EE+   + +AE  A   +G G  E      H HVG+ Q   E V      V+ AH   H
Sbjct: 151 -EEEAAVEVSAEAQADG-DGKGDGEE----PHGHVGRSQGHQEVVGGRLQSVRRAHRGAH 204

Query: 253 QHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPVARRGLCA 307
           QH   VA       D +++H Q +  + Q     GR  W+  A +R  A RG  A
Sbjct: 205 QH---VARHRKRGDDQLQRHVQRVLCLQQ----HGRASWAPGAPYRRRAGRGAAA 252


>gi|169210802 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 252

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 53/175 (30%), Positives = 73/175 (41%), Gaps = 27/175 (15%)

Query: 144 QRQHRGQRPDGQHSVGAEAQRDAP--PQRVHQHDVAVHC------DGGEREHRHIDGDRL 195
           Q   +G+ P+  +       RD    P+R     V+V C      DG  REH+H  G   
Sbjct: 94  QSDAKGKDPEDSNDPSCSGPRDQTFIPERDTDGQVSVDCHGQKAEDGALREHQHEAG--- 150

Query: 196 QEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV---RHVVQPAHPRDH 252
            EE+   + +AE  A   +G G  E      H HVG+ Q   E V      V+ AH   H
Sbjct: 151 -EEEAAVEVSAEAQADG-DGKGDGEE----PHGHVGRSQGHQEVVGGRLQSVRRAHRGAH 204

Query: 253 QHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEGRDGWSVRASHRPVARRGLCA 307
           QH   VA       D +++H Q +  + Q     GR  W+  A +R  A RG  A
Sbjct: 205 QH---VARHRKRGDDQLQRHVQRVLCLQQ----HGRASWAPGAPYRRRAGRGAAA 252


>gi|239757829 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 51/158 (32%), Positives = 71/158 (44%), Gaps = 24/158 (15%)

Query: 70  PADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVG-----DQQQPPGVELALALLGAPELL 124
           PA+G+ HHDHH Q  G  AP A P + Q  + VG     DQQ   G + A   L  P+  
Sbjct: 30  PAEGKGHHDHHHQPHGPQAPLA-PGNQQHGQDVGIAVGHDQQ---GQQKASHQLQHPQSR 85

Query: 125 AEAHVVRLELHVIGVHG----GGQR------QHRGQRPDGQHSVGAEAQRDAPPQR---V 171
           A AH+  + L V GV      G Q       + + + PD Q   G  A R  P      +
Sbjct: 86  A-AHLWEVVLAVGGVEALVVVGRQEDEVWEGEKQAEPPDSQAGEG-HAGRGPPAVELGGM 143

Query: 172 HQHDVAVHCDGGEREHRHIDGDRLQEEDQVAQAAAEHP 209
           +   VAV  D G++E   ++ D  +     A+A A+ P
Sbjct: 144 NYVQVAVKADAGQQEGSCVEVDVEEGTCHFAEARAKDP 181


>gi|239752340 PREDICTED: hypothetical protein XP_002348205 [Homo
           sapiens]
          Length = 218

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 51/158 (32%), Positives = 71/158 (44%), Gaps = 24/158 (15%)

Query: 70  PADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVG-----DQQQPPGVELALALLGAPELL 124
           PA+G+ HHDHH Q  G  AP A P + Q  + VG     DQQ   G + A   L  P+  
Sbjct: 46  PAEGKGHHDHHHQPHGPQAPLA-PGNQQHGQDVGIAVGHDQQ---GQQKASHQLQHPQSR 101

Query: 125 AEAHVVRLELHVIGVHG----GGQR------QHRGQRPDGQHSVGAEAQRDAPPQR---V 171
           A AH+  + L V GV      G Q       + + + PD Q   G  A R  P      +
Sbjct: 102 A-AHLWEVVLAVGGVEALVVVGRQEDEVWEGEKQAEPPDSQAGEG-HAGRGPPAVELGGM 159

Query: 172 HQHDVAVHCDGGEREHRHIDGDRLQEEDQVAQAAAEHP 209
           +   VAV  D G++E   ++ D  +     A+A A+ P
Sbjct: 160 NYVQVAVKADAGQQEGSCVEVDVEEGTCHFAEARAKDP 197


>gi|239746853 PREDICTED: hypothetical protein XP_002343864 [Homo
           sapiens]
          Length = 218

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 51/158 (32%), Positives = 71/158 (44%), Gaps = 24/158 (15%)

Query: 70  PADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVG-----DQQQPPGVELALALLGAPELL 124
           PA+G+ HHDHH Q  G  AP A P + Q  + VG     DQQ   G + A   L  P+  
Sbjct: 46  PAEGKGHHDHHHQPHGPQAPLA-PGNQQHGQDVGIAVGHDQQ---GQQKASHQLQHPQSR 101

Query: 125 AEAHVVRLELHVIGVHG----GGQR------QHRGQRPDGQHSVGAEAQRDAPPQR---V 171
           A AH+  + L V GV      G Q       + + + PD Q   G  A R  P      +
Sbjct: 102 A-AHLWEVVLAVGGVEALVVVGRQEDEVWEGEKQAEPPDSQAGEG-HAGRGPPAVELGGM 159

Query: 172 HQHDVAVHCDGGEREHRHIDGDRLQEEDQVAQAAAEHP 209
           +   VAV  D G++E   ++ D  +     A+A A+ P
Sbjct: 160 NYVQVAVKADAGQQEGSCVEVDVEEGTCHFAEARAKDP 197


>gi|221316609 sperm-associated cation channel 1 [Homo sapiens]
          Length = 780

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 61/258 (23%), Positives = 81/258 (31%), Gaps = 58/258 (22%)

Query: 60  PQQVEDVQRQPADGEHHHDHHQ-------QAEG------APAPSAVP------------- 93
           P + +D   Q      H  HH        +A G      AP+  AVP             
Sbjct: 60  PPEFQDFHDQALSSHVHQSHHHSEARNHGRAHGPTGFGLAPSQGAVPSHRSYGEDYHDEL 119

Query: 94  EDDQQREQVGDQ-----QQPPGVELALALLGAPELLAEA---HVVRLELHVIGVHGGGQR 145
           + D +R   G Q     QQ        +  G P+ L E    +   +  H    H GG  
Sbjct: 120 QRDGRRHHDGSQYGGFHQQSDSHYHRGSHHGRPQYLGENLSHYSSGVPHHGEASHHGGSY 179

Query: 146 QHRGQRP--------DGQHSVGA---EAQRDAPPQRVHQHDVAVHCDGGEREHR-HIDGD 193
              G  P        +  H  G    E+Q    P R   H   VH  G  R H  H  G 
Sbjct: 180 LPHGPNPYSESFHHSEASHLSGLQHDESQHHQVPHRGWPHHHQVHHHGRSRHHEAHQHGK 239

Query: 194 RLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEVRHVVQPAHPRDHQ 253
                + ++  ++         +G  +R     H    QG     E  H   P H + H 
Sbjct: 240 SPHHGETISPHSS---------VGSYQRGISDYHSEYHQGDHHPSEYHHGDHPHHTQHHY 290

Query: 254 HQ---QAVAHQPHDHHDA 268
           HQ       HQ  DHH A
Sbjct: 291 HQTHRHRDYHQHQDHHGA 308


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 42/170 (24%), Positives = 59/170 (34%), Gaps = 35/170 (20%)

Query: 136 VIGVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHCDGGEREHRHI----- 190
           V   HGG  R HRG   +      AE +   P  R H H      +    EH H      
Sbjct: 123 VFAEHGGQARGHRGHGSEDTED-SAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHG 181

Query: 191 ----DGD------RLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEV 240
               DG+        +EE++  +A+ E              +   AH H G G   DE+V
Sbjct: 182 HRGHDGEDDEGEEEEEEEEEEEEASTE--------------YGHQAHRHRGHGSEEDEDV 227

Query: 241 ---RHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHDQPLQLMHQLQALEG 287
               H   P+H   HQ  +       D  D  +  D  ++  HQ    +G
Sbjct: 228 SDGHHHHGPSH--RHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQG 275



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 62/261 (23%), Positives = 85/261 (32%), Gaps = 59/261 (22%)

Query: 61  QQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELALALLGA 120
           ++ EDV    +DG HHH    + +G        EDD   +   D      V +       
Sbjct: 222 EEDEDV----SDGHHHHGPSHRHQGHE------EDDDDDDDDDDDDDDDDVSI------- 264

Query: 121 PELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHC 180
            E   +AH  R + H I         H  + P  +H    E   D         D  V  
Sbjct: 265 -EYRHQAH--RHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDDND---------DDDVST 312

Query: 181 DGGEREHRHIDGDRLQEEDQVAQAAAEHPAAWLEGIGQRER-----------HAGGAHEH 229
           + G + HRH   D  +EE +       H        G R+            H G  H H
Sbjct: 313 EYGHQAHRH--QDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTERWHQGPQHVH 370

Query: 230 VGQGQVADEEVRHVVQPAH------PRDHQ------HQQAVAHQPHDHHDAVEQHDQPLQ 277
            G     +EE    VQ  H      PR H+        +     PH HH     H  P +
Sbjct: 371 HGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHH-----HRVPRE 425

Query: 278 LMHQLQALEGRDGWSVRASHR 298
              ++ A  G    S R SH+
Sbjct: 426 EDEEVSAELGHQAPSHRQSHQ 446


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 53/223 (23%), Positives = 84/223 (37%), Gaps = 27/223 (12%)

Query: 41   AEQLHQPKGVRVDGVGVEVPQQ---------VEDVQRQPADGEHHHDHHQQAEGAPAPSA 91
            AE+  QP+   V+ + VEV  Q          EDV+   A+GE      +    +    A
Sbjct: 1966 AEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEA 2025

Query: 92   VP--EDDQQREQVGDQQQPPG-VELALALLGAPELLAEAHVVRLELHVIGVHGGGQRQHR 148
             P  E ++ +E  G+ Q+  G  +     + APE   EA     E+         Q    
Sbjct: 2026 QPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEV---------QEAEG 2076

Query: 149  GQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHCDGGEREHRHIDGDRLQEEDQVAQAAAEH 208
               P+ +     EA+ +A P+   +   A   +G  ++   I+    + E Q      E 
Sbjct: 2077 EAHPESEDVDAQEAEGEAQPE--SEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEA 2134

Query: 209  PAAWLEGIGQRERHAGGAHEHVGQGQVADE--EVRHVVQPAHP 249
            P A  EG  Q E     A +  G+ Q   E  E +   + A P
Sbjct: 2135 PEA--EGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQP 2175



 Score = 36.2 bits (82), Expect = 0.040
 Identities = 57/271 (21%), Positives = 92/271 (33%), Gaps = 24/271 (8%)

Query: 24   PGVDEGVVAGRTHGEPVAEQLHQPKGVRVDGVGVEVPQQVEDVQRQPADGEHHHDHHQQA 83
            PGVDEG       G     +   PK    +G  +   ++ +    + + G    +  Q+ 
Sbjct: 1738 PGVDEGEDG---EGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEG 1794

Query: 84   EGAP------APSAVPEDDQQREQVGDQQQPPGVELALALLGAPELLAEAHVVRLELHVI 137
            EG           +  ED+ Q E      Q PG       + APE   EA      +   
Sbjct: 1795 EGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAP 1854

Query: 138  GVHGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHCDGGEREHRHIDGDRLQE 197
               G  Q      +P+ +     EA+ +A P+     DV    +         +G    E
Sbjct: 1855 EAEGDAQEAEGEAQPESEDVEAPEAEGEAQPE---SEDVETP-EAEWEVQPESEGAEAPE 1910

Query: 198  EDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEVRHVVQPAHPRDHQHQQA 257
             ++ AQ   E   A LE  G+ E  + GA           +E     Q A  +     + 
Sbjct: 1911 AEKEAQPETESVEA-LETEGEDEPESEGAEA---------QEAEEAAQEAEGQTQPESEV 1960

Query: 258  VAHQPHDHHDAVEQHD-QPLQLMHQLQALEG 287
            +  Q  +     E  D + L++  + Q  EG
Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVETQEAEG 1991



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 54/214 (25%), Positives = 78/214 (36%), Gaps = 31/214 (14%)

Query: 39   PVAEQLHQPKGVRVDGVGVEVPQQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQ 98
            P AE+  Q     V     E   + EDV  Q A+GE       ++EG  AP A  E  + 
Sbjct: 2058 PEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGE----AQPESEGVEAPEAEGEAQKA 2113

Query: 99   R-----EQVGD-QQQPPGVELALALLGAPELLAEAHVVRLELHVIGVHGGGQRQHRG--- 149
                  E  G+ Q +  G+E       APE   EA      +      G  Q +  G   
Sbjct: 2114 EGIEAPETEGEAQPESEGIE-------APEAEGEAQPESEGVEAQDAEGEAQPESEGIEA 2166

Query: 150  ------QRPDGQHSVGAEAQRDAPPQRVHQHDVAVHCDG-GEREHRHIDGDRLQEEDQVA 202
                   +P+ +     EA+ +A P+   +   A   +G  + E   ++    +EE Q  
Sbjct: 2167 QEAEEEAQPELEGVEAPEAEGEAQPE--SEGIEAPEAEGEAQPELEGVEAPEAEEEAQPE 2224

Query: 203  QAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVA 236
                E P A  EG  Q E       E  G  QV+
Sbjct: 2225 PEGVETPEA--EGEAQPESEGETQGEKKGSPQVS 2256


>gi|4506885 semenogelin II precursor [Homo sapiens]
          Length = 582

 Score = 36.2 bits (82), Expect = 0.040
 Identities = 35/153 (22%), Positives = 58/153 (37%), Gaps = 31/153 (20%)

Query: 140 HGGGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHCDGGEREHRHIDGDRLQEED 199
           H GG +Q    + +G         RD    + H H + +H  GG+  H    G +   +D
Sbjct: 99  HLGGSQQLLNYKQEG---------RDHDKSKGHFHMIVIHHKGGQAHH----GTQNPSQD 145

Query: 200 Q---------VAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEVRHVVQPAH-- 248
           Q          +Q +      W+ G+ + +  A GA +   QG     +  +V+Q     
Sbjct: 146 QGNSPSGKGLSSQCSNTEKRLWVHGLSKEQASASGAQKGRTQG---GSQSSYVLQTEELV 202

Query: 249 PRDHQHQQAVAHQPHDHH----DAVEQHDQPLQ 277
               Q +   +HQ   H+    D  E+H   LQ
Sbjct: 203 VNKQQRETKNSHQNKGHYQNVVDVREEHSSKLQ 235


>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
           subunit [Homo sapiens]
          Length = 2339

 Score = 35.8 bits (81), Expect = 0.052
 Identities = 31/115 (26%), Positives = 42/115 (36%), Gaps = 11/115 (9%)

Query: 143 GQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHCDGGEREHRHIDGDRLQEEDQVA 202
           G+   R +RP    S   EA    PP+   +       +GG R HR    +   E +   
Sbjct: 877 GEPGAREERPRPHRSHSKEAA--GPPEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRR 934

Query: 203 QAAAEHPAAWLEGIG----QRERHAGGAHEHVGQGQVADE-----EVRHVVQPAH 248
             A  H     E  G    +R RH GG      + +  +E       RH  QPAH
Sbjct: 935 HRAHRHQDPSKECAGAKGERRARHRGGPRAGPREAESGEEPARRHRARHKAQPAH 989


>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
          Length = 696

 Score = 35.8 bits (81), Expect = 0.052
 Identities = 58/251 (23%), Positives = 99/251 (39%), Gaps = 45/251 (17%)

Query: 58  EVPQQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQRE----QVGDQQQPPGVEL 113
           +V Q  E V  +  D + +   H++AE    P  + ++ ++RE    QV ++ +    E 
Sbjct: 287 DVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEE 346

Query: 114 ALALLGAPELLAEAH--------------------VVRLELHVIG-VHGGGQRQHRGQRP 152
            +  +G  E L E H                       LE H    V+   +   + Q P
Sbjct: 347 EMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSP 406

Query: 153 DGQHSVGAEAQRDA-----PPQRVHQHDVAVHCDGGEREHRHIDGDRLQEEDQVA-QAAA 206
              +    E QR A       Q++ +H  A+H    +R   H+   + Q++ QVA + A 
Sbjct: 407 ---YEEQLEQQRLAVQQVEEAQQLREHQEALH---QQRLQGHLLRQQEQQQQQVAREMAL 460

Query: 207 EHPAAWLEGIGQRER------HAGGAHEHVGQGQVADEEVRHVVQPAHPRDHQHQQAVAH 260
           +  A   EG  Q +       H       + QG  A+++     + A+ RD+QHQ     
Sbjct: 461 QRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQG--AEDQGIQGEEGAYERDNQHQDEAEG 518

Query: 261 QPHDHHDAVEQ 271
            P + H+  EQ
Sbjct: 519 DPGNRHEPREQ 529



 Score = 32.7 bits (73), Expect = 0.44
 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 11/101 (10%)

Query: 3   GYLAGPSDQQFAQLLAEAVVQPGVDEGVVAGRT-HGEPVAEQLHQPKGVRVDGVGVEVPQ 61
           G+L    +QQ  Q+  E  +Q   +  +  GR  H E + +Q H       D +  ++ Q
Sbjct: 441 GHLLRQQEQQQQQVAREMALQRQAE--LEEGRPQHQEQLRQQAHY------DAMDNDIVQ 492

Query: 62  QVEDVQRQPADGEHHHD--HHQQAEGAPAPSAVPEDDQQRE 100
             ED   Q  +G +  D  H  +AEG P     P +   RE
Sbjct: 493 GAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPRE 533



 Score = 28.5 bits (62), Expect = 8.4
 Identities = 31/128 (24%), Positives = 49/128 (38%), Gaps = 7/128 (5%)

Query: 161 EAQRDAPPQRVHQHDVAVHCDGGEREHRHIDGDRLQEEDQVAQA---AAEHPAAWLEGIG 217
           EA+  APP+ + Q       +  + E  H      +E +QV QA     EH  +  E   
Sbjct: 311 EAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEE--- 367

Query: 218 QRERHAGGAHEHVGQGQVADEEVRHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHDQPLQ 277
            ++R     HE      + +   R  V P+     + Q     Q      AV+Q ++  Q
Sbjct: 368 -QDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQ 426

Query: 278 LMHQLQAL 285
           L    +AL
Sbjct: 427 LREHQEAL 434


>gi|239752979 PREDICTED: hypothetical protein XP_002345320 [Homo
           sapiens]
          Length = 243

 Score = 35.0 bits (79), Expect = 0.089
 Identities = 37/125 (29%), Positives = 47/125 (37%), Gaps = 14/125 (11%)

Query: 152 PDGQHSVGAEAQRDA--PPQRVHQHDVAVH--CDGGEREHRHIDGDRLQEEDQVAQ-AAA 206
           P  Q S GA +   A   P+R    +VAVH  C  G+      DG   ++ED+     A 
Sbjct: 118 PSSQPSCGAASTFGAVDSPERDLDPEVAVHSNCQQGQ------DGALGEDEDRTGNHEAG 171

Query: 207 EHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEVRHVVQPA---HPRDHQHQQAVAHQPH 263
                W       E    G H H+   Q  DE    + Q     H  DHQH      Q  
Sbjct: 172 VEVGLWPNVDEDGEGDDQGTHGHISHRQRHDEAEGGIPQRLVHLHRPDHQHVPGHRDQGD 231

Query: 264 DHHDA 268
           +H DA
Sbjct: 232 EHLDA 236


>gi|239747560 PREDICTED: hypothetical protein XP_002347649 [Homo
           sapiens]
          Length = 284

 Score = 35.0 bits (79), Expect = 0.089
 Identities = 37/125 (29%), Positives = 47/125 (37%), Gaps = 14/125 (11%)

Query: 152 PDGQHSVGAEAQRDA--PPQRVHQHDVAVH--CDGGEREHRHIDGDRLQEEDQVAQ-AAA 206
           P  Q S GA +   A   P+R    +VAVH  C  G+      DG   ++ED+     A 
Sbjct: 159 PSSQPSCGAASTFGAVDSPERDLDPEVAVHSNCQQGQ------DGALGEDEDRTGNHEAG 212

Query: 207 EHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEVRHVVQPA---HPRDHQHQQAVAHQPH 263
                W       E    G H H+   Q  DE    + Q     H  DHQH      Q  
Sbjct: 213 VEVGLWPNVDEDGEGDDQGTHGHISHRQRHDEAEGGIPQRLVHLHRPDHQHVPGHRDQGD 272

Query: 264 DHHDA 268
           +H DA
Sbjct: 273 EHLDA 277


>gi|239741434 PREDICTED: hypothetical protein XP_002342199 [Homo
           sapiens]
          Length = 284

 Score = 35.0 bits (79), Expect = 0.089
 Identities = 37/125 (29%), Positives = 47/125 (37%), Gaps = 14/125 (11%)

Query: 152 PDGQHSVGAEAQRDA--PPQRVHQHDVAVH--CDGGEREHRHIDGDRLQEEDQVAQ-AAA 206
           P  Q S GA +   A   P+R    +VAVH  C  G+      DG   ++ED+     A 
Sbjct: 159 PSSQPSCGAASTFGAVDSPERDLDPEVAVHSNCQQGQ------DGALGEDEDRTGNHEAG 212

Query: 207 EHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEVRHVVQPA---HPRDHQHQQAVAHQPH 263
                W       E    G H H+   Q  DE    + Q     H  DHQH      Q  
Sbjct: 213 VEVGLWPNVDEDGEGDDQGTHGHISHRQRHDEAEGGIPQRLVHLHRPDHQHVPGHRDQGD 272

Query: 264 DHHDA 268
           +H DA
Sbjct: 273 EHLDA 277


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 5/41 (12%)

Query: 74  EHHHDHHQQAEGAPA-----PSAVPEDDQQREQVGDQQQPP 109
           +HHH HHQQ + APA     P   P+          QQQPP
Sbjct: 737 KHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPP 777


>gi|4501879 acrosomal vesicle protein 1 isoform a precursor [Homo
           sapiens]
          Length = 265

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 10/96 (10%)

Query: 74  EHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQ---QQPPGVELALALLGAPELLAEAHVV 130
           EH    H ++E A    A  E  +    VG+Q   +QP G  L+      P    E+   
Sbjct: 82  EHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGE---QPLSELESGEQ 138

Query: 131 RLELHVIGVHGGGQR----QHRGQRPDGQHSVGAEA 162
             +    G HG G++    Q  G++P G+H+ G +A
Sbjct: 139 PSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQA 174


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 57/272 (20%), Positives = 85/272 (31%), Gaps = 44/272 (16%)

Query: 34   RTHGEPVAEQLHQPKGVRVDGV-------GVEVPQQVEDVQRQPADGEHHHDHHQQAEGA 86
            R+H E  A   H  +  R  G        G +     E  Q + + GE H  HHQQ+   
Sbjct: 2283 RSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHE--QARSSAGERHGSHHQQS--- 2337

Query: 87   PAPSAVPEDDQQREQVGDQQQPPGVELA--LALLGAPELLAEAHVVRLELHVIGVHG-GG 143
                    D  +   +G  Q    V  +      G+    +E H    +   +  HG  G
Sbjct: 2338 -------ADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAG 2390

Query: 144  QRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHCDG------GEREHRHIDGDRLQE 197
              Q   Q      S G   +  +   +V  H+ +    G      G R+  H    R   
Sbjct: 2391 PHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSS 2450

Query: 198  EDQVAQAAAE----HP--------AAWLEGIGQRERHAGGAHEHVGQGQVADEEVRHVVQ 245
                +Q   +    HP         +  E +  R  H+G  H H      +D    H   
Sbjct: 2451 RHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGS 2510

Query: 246  PAHPR----DHQHQQAVAHQPHDHHDAVEQHD 273
             +  R    D Q      H    HH+A  + D
Sbjct: 2511 RSASRQTRNDEQSGDGSRHSGSRHHEASSRAD 2542



 Score = 32.0 bits (71), Expect = 0.76
 Identities = 48/234 (20%), Positives = 72/234 (30%), Gaps = 39/234 (16%)

Query: 67   QRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELALALLGAPELLAE 126
            Q + + GE H   HQQ+  +   S +P   Q    V D +            G+    +E
Sbjct: 3293 QARSSPGERHGSRHQQSADSSRHSGIPR-GQASSAVRDSRH-------WGSSGSQASDSE 3344

Query: 127  AHVVRLELHVIGVHG-GGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHCDG--- 182
             H    +   +  HG  G  Q   Q      S G   +  +   +V  H+ +    G   
Sbjct: 3345 GHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTR 3404

Query: 183  ---GEREHRHIDGDRLQEEDQVAQAAAE----HPAAWLEG--------IGQRERHAGGAH 227
               G R+  H +  R       +Q   +    HP +   G           R  H+G  H
Sbjct: 3405 TSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHH 3464

Query: 228  EH--------VGQGQVADEEVRHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHD 273
             H          +GQ          +     D Q      H    HH+A  Q D
Sbjct: 3465 SHTTSQGRSDASRGQSGSRSASRQTR----NDEQSGDGSRHSWSHHHEASTQAD 3514



 Score = 32.0 bits (71), Expect = 0.76
 Identities = 47/232 (20%), Positives = 73/232 (31%), Gaps = 35/232 (15%)

Query: 67   QRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQPPGVELA--LALLGAPELL 124
            Q + + GE H  HHQQ+           D  +   +G  Q    V  +      G+    
Sbjct: 3617 QARSSAGERHGSHHQQS----------ADSSRHSGIGHGQASSAVRDSGHRGSSGSQASD 3666

Query: 125  AEAHVVRLELHVIGVHG-GGQRQHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHCDG- 182
            +E H    +   +  HG  G  Q   Q      S G   +  +   +V  H+ +    G 
Sbjct: 3667 SEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGR 3726

Query: 183  ---------GEREHRHIDGDRLQEEDQVAQAAAEHP--------AAWLEGIGQRERHAGG 225
                     G R  +  D  R     +       HP         ++ E    R  H+G 
Sbjct: 3727 AGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGS 3786

Query: 226  AHEH-VGQGQVADEEVRHVVQPAHPRDHQHQQA---VAHQPHDHHDAVEQHD 273
             H H   QG+      +   + A       +Q+     H    HH+A  Q D
Sbjct: 3787 HHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQAD 3838



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 57/270 (21%), Positives = 84/270 (31%), Gaps = 40/270 (14%)

Query: 34   RTHGEPVAEQLHQPKGVRVDGV-------GVEVPQQVEDVQRQPADGEHHHDHHQQAEGA 86
            R+H E  A   H     R  G        G +     E  +  P  GE H   HQQ+  +
Sbjct: 986  RSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSP--GERHGSRHQQSADS 1043

Query: 87   PAPSAVPEDDQQREQVGDQQQPPGVELALALLGAPELLAEAHVVRLELHVIGVHG-GGQR 145
               S +P     R Q     +  G        G+    +E H    +   +  HG  G  
Sbjct: 1044 SRHSGIP-----RRQASSAVRDSG---HWGSSGSQASDSEGHSEESDTQSVSGHGQDGPH 1095

Query: 146  QHRGQRPDGQHSVGAEAQRDAPPQRVHQHDVAVHCDG------GEREHRHIDGDRLQEED 199
            Q   Q      S G   +  +   +V  H+ +    G      G R+  H +  R     
Sbjct: 1096 QQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRH 1155

Query: 200  QVAQAAAE----HPAAWLEG--------IGQRERHAGGAHEH-VGQGQVADEEVRHVVQP 246
              +Q   +    HP +   G           R  H+G  H H   QG+      +   + 
Sbjct: 1156 SASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRS 1215

Query: 247  AH---PRDHQHQQAVAHQPHDHHDAVEQHD 273
            A     +D Q      H    HH+A    D
Sbjct: 1216 ASRQTRKDKQSGDGSRHSGSRHHEAASWAD 1245



 Score = 28.9 bits (63), Expect = 6.4
 Identities = 53/274 (19%), Positives = 78/274 (28%), Gaps = 48/274 (17%)

Query: 34   RTHGEPVAEQLHQPKGVRVDGV-------GVEVPQQVEDVQRQPADGEHHHDHHQQAEGA 86
            R+H E  A   H  +  R  G        G +     E  +  P  GE H   HQQ+  +
Sbjct: 1634 RSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSP--GERHGSRHQQSADS 1691

Query: 87   PAPSAVPEDDQQREQVGDQQQPPGVELALALLGAPELLAEAHVVRLELHVIGVHGGGQRQ 146
               S      Q    VGD              G+    +E H    +   +  HG     
Sbjct: 1692 STDSGTGR-RQDSSVVGDSGN-------RGSSGSQASDSEGHSEESDTQSVSAHGQAGPH 1743

Query: 147  HRGQRPDGQHSVGAEAQRDAP---PQRVHQHDVAVH-----CDGGEREHRH---IDGDRL 195
             +  +   +   G  + R          H+   + H       GG +  RH    D  R 
Sbjct: 1744 QQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRH 1803

Query: 196  QEEDQVAQAAAEHP--------AAWLEGIGQRERHAGGAHEH--------VGQGQVADEE 239
                +       HP         +  E       H+G  H H        V +GQ     
Sbjct: 1804 SASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRS 1863

Query: 240  VRHVVQPAHPRDHQHQQAVAHQPHDHHDAVEQHD 273
            V    +     + Q      H    HH+A  + D
Sbjct: 1864 VSRQTR----NEKQSGDGSRHSGSRHHEASSRAD 1893


>gi|93141033 PAX interacting protein 1 [Homo sapiens]
          Length = 1069

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 194 RLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHEHVGQGQVADEEVRHVVQPAHPRDHQ 253
           +LQ++ Q   +   +P        Q+++    AH H    Q + ++++   Q  HP    
Sbjct: 426 QLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPH----QFSQQQLQFPQQQLHPPQQL 481

Query: 254 HQQAVAHQPHDHHDAVEQHDQPLQLMHQLQ 283
           H+     QP     A++Q    LQ  HQLQ
Sbjct: 482 HRPQQQLQPFQQQHALQQQFHQLQ-QHQLQ 510



 Score = 28.5 bits (62), Expect = 8.4
 Identities = 24/112 (21%), Positives = 37/112 (33%), Gaps = 30/112 (26%)

Query: 61  QQVEDVQRQPADGEHHHDHHQQAEGAPAPSAVPEDDQQREQVGDQQQP------------ 108
           QQ + +Q+Q     H     QQ +   AP         + QV  QQ P            
Sbjct: 527 QQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSP 586

Query: 109 ---------PGVEL---------ALALLGAPELLAEAHVVRLELHVIGVHGG 142
                    P VE+           A+   PE +++  ++     +I  HGG
Sbjct: 587 QQHQLFGHDPAVEIPEEGFLLGCVFAIADYPEQMSDKQLLATWKRIIQAHGG 638


>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
          Length = 446

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 23/97 (23%), Positives = 38/97 (39%), Gaps = 12/97 (12%)

Query: 15  QLLAEAVVQPGVDEGVVAGRTHGEPVAEQLHQPKGVRVDGVGVEVPQQVEDVQRQPA--- 71
           +LL+E+  +P V+E       H +   +  +QP+  +    G        ++   P    
Sbjct: 141 RLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHSDSDSGAELGPHPGGGA 200

Query: 72  ---------DGEHHHDHHQQAEGAPAPSAVPEDDQQR 99
                    DG HH DH  Q  G P P   P+ + Q+
Sbjct: 201 VYKAEAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQ 237


>gi|118766339 thyroid transcription factor 1 isoform 1 [Homo
           sapiens]
          Length = 401

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 34/124 (27%), Positives = 43/124 (34%), Gaps = 15/124 (12%)

Query: 42  EQLHQPKGVRVDGVGVEVPQQVEDVQRQP---ADGEHHHDHHQQAEGAPAPSAVPEDDQQ 98
           +QL Q  G    G G   PQQ +  Q+ P   A      D      GAPAP A       
Sbjct: 257 QQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGAPAPGAASLQGHA 316

Query: 99  REQVGDQQQPPGVELALALLGAPELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSV 158
           ++Q   Q Q      A   +G+                +G H G Q    GQ PD  H  
Sbjct: 317 QQQAQHQAQAAQAAAAAISVGSGGA------------GLGAHPGHQPGSAGQSPDLAHHA 364

Query: 159 GAEA 162
            + A
Sbjct: 365 ASPA 368


>gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]
          Length = 371

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 34/124 (27%), Positives = 43/124 (34%), Gaps = 15/124 (12%)

Query: 42  EQLHQPKGVRVDGVGVEVPQQVEDVQRQP---ADGEHHHDHHQQAEGAPAPSAVPEDDQQ 98
           +QL Q  G    G G   PQQ +  Q+ P   A      D      GAPAP A       
Sbjct: 227 QQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGAPAPGAASLQGHA 286

Query: 99  REQVGDQQQPPGVELALALLGAPELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQHSV 158
           ++Q   Q Q      A   +G+                +G H G Q    GQ PD  H  
Sbjct: 287 QQQAQHQAQAAQAAAAAISVGSGGA------------GLGAHPGHQPGSAGQSPDLAHHA 334

Query: 159 GAEA 162
            + A
Sbjct: 335 ASPA 338


>gi|239755420 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 171

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 22/117 (18%)

Query: 154 GQHSVGAEAQRDA------PPQRVHQHDVAVHCDGGEREHRHIDGDRLQEEDQVAQAAAE 207
           G   VG + QR+A      P ++VH   V     GGE +        LQ    +++AA  
Sbjct: 65  GVPHVGVDGQREAAETSAAPLRQVHDGLVLELAAGGEIQ-------LLQGRAAISEAAQR 117

Query: 208 HPAAWLEGIGQRERHAGGAHEHVGQG------QVADEEVRHVVQPAHPRDHQHQQAV 258
            P   +  +  RER A  A   +GQ       Q+     RH  Q   PR H+HQ  V
Sbjct: 118 QP---VHPVTVRERQALQAWAALGQSPKRPATQLPAAAQRHTPQLRIPRQHRHQVLV 171


>gi|239749896 PREDICTED: hypothetical protein XP_002347199 isoform 2
           [Homo sapiens]
          Length = 171

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 22/117 (18%)

Query: 154 GQHSVGAEAQRDA------PPQRVHQHDVAVHCDGGEREHRHIDGDRLQEEDQVAQAAAE 207
           G   VG + QR+A      P ++VH   V     GGE +        LQ    +++AA  
Sbjct: 65  GVPHVGVDGQREAAETSAAPLRQVHDGLVLELAAGGEIQ-------LLQGRAAISEAAQR 117

Query: 208 HPAAWLEGIGQRERHAGGAHEHVGQG------QVADEEVRHVVQPAHPRDHQHQQAV 258
            P   +  +  RER A  A   +GQ       Q+     RH  Q   PR H+HQ  V
Sbjct: 118 QP---VHPVTVRERQALQAWAALGQSPKRPATQLPAAAQRHTPQLRIPRQHRHQVLV 171


>gi|239749894 PREDICTED: hypothetical protein XP_002347198 isoform 1
           [Homo sapiens]
          Length = 171

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 22/117 (18%)

Query: 154 GQHSVGAEAQRDA------PPQRVHQHDVAVHCDGGEREHRHIDGDRLQEEDQVAQAAAE 207
           G   VG + QR+A      P ++VH   V     GGE +        LQ    +++AA  
Sbjct: 65  GVPHVGVDGQREAAETSAAPLRQVHDGLVLELAAGGEIQ-------LLQGRAAISEAAQR 117

Query: 208 HPAAWLEGIGQRERHAGGAHEHVGQG------QVADEEVRHVVQPAHPRDHQHQQAV 258
            P   +  +  RER A  A   +GQ       Q+     RH  Q   PR H+HQ  V
Sbjct: 118 QP---VHPVTVRERQALQAWAALGQSPKRPATQLPAAAQRHTPQLRIPRQHRHQVLV 171


>gi|239744196 PREDICTED: hypothetical protein XP_002343054 [Homo
           sapiens]
          Length = 171

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 22/117 (18%)

Query: 154 GQHSVGAEAQRDA------PPQRVHQHDVAVHCDGGEREHRHIDGDRLQEEDQVAQAAAE 207
           G   VG + QR+A      P ++VH   V     GGE +        LQ    +++AA  
Sbjct: 65  GVPHVGVDGQREAAETSAAPLRQVHDGLVLELAAGGEIQ-------LLQGRAAISEAAQR 117

Query: 208 HPAAWLEGIGQRERHAGGAHEHVGQG------QVADEEVRHVVQPAHPRDHQHQQAV 258
            P   +  +  RER A  A   +GQ       Q+     RH  Q   PR H+HQ  V
Sbjct: 118 QP---VHPVTVRERQALQAWAALGQSPKRPATQLPAAAQRHTPQLRIPRQHRHQVLV 171


>gi|44890059 involucrin [Homo sapiens]
          Length = 585

 Score = 33.1 bits (74), Expect = 0.34
 Identities = 57/253 (22%), Positives = 99/253 (39%), Gaps = 27/253 (10%)

Query: 61  QQVEDVQRQPADGE---HHHDHHQQAEGAPAP------SAVPEDDQQREQVGDQQQPPGV 111
           Q+ E  Q++P + E    H + H++ + A  P           D Q  +Q+ ++++    
Sbjct: 73  QECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQ 132

Query: 112 ELALALLGAPELLAEAHVVRLELHVIGVHGGGQRQHRGQRPDGQ--HSVGAEAQRDAPPQ 169
           +L   L+   E L       LEL        G  +H  Q+ +GQ  H    E Q + P Q
Sbjct: 133 QLDQELVKRDEQLGMKKEQLLEL---PEQQEGHLKHLEQQ-EGQLKHPEQQEGQLELPEQ 188

Query: 170 RVHQHDVAVHCDGGEREHRHIDGD-RLQEEDQVAQAAAEHPAAWLEGIGQRERHAGGAHE 228
           +  Q ++    +G        +G   L E+ +      E     LE   Q+E     + +
Sbjct: 189 QEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQ 248

Query: 229 HVGQGQVADEEVRHVVQPAH-------PRDHQHQQAVAHQPH---DHHDAVE-QHDQPLQ 277
             GQ ++++++   +    H       P +   Q     Q      H D  E Q + P Q
Sbjct: 249 QEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQ 308

Query: 278 LMHQLQALEGRDG 290
            M QL+ LE ++G
Sbjct: 309 QMGQLKHLEQQEG 321


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,282,437
Number of Sequences: 37866
Number of extensions: 836660
Number of successful extensions: 3857
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 122
Number of HSP's that attempted gapping in prelim test: 3398
Number of HSP's gapped (non-prelim): 454
length of query: 321
length of database: 18,247,518
effective HSP length: 102
effective length of query: 219
effective length of database: 14,385,186
effective search space: 3150355734
effective search space used: 3150355734
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.