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Search of human proteins with 118918413
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118918413 MICAL C-terminal like [Homo sapiens]
(695 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118918413 MICAL C-terminal like [Homo sapiens] 1382 0.0
gi|209862789 microtubule associated monoxygenase, calponin and L... 205 1e-52
gi|205360947 microtubule associated monoxygenase, calponin and L... 119 9e-27
gi|226530313 microtubule associated monoxygenase, calponin and L... 119 9e-27
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens] 106 8e-23
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 98 3e-20
gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens] 91 5e-18
gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens] 91 5e-18
gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens] 91 5e-18
gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens] 91 5e-18
gi|150378549 tangerin [Homo sapiens] 84 4e-16
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 67 7e-11
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 66 9e-11
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 64 4e-10
gi|148746195 trichohyalin [Homo sapiens] 61 3e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 60 7e-09
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 60 9e-09
gi|171906567 peripheral benzodiazepine receptor-associated prote... 58 3e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 57 6e-08
gi|60460889 Myb protein P42POP [Homo sapiens] 57 6e-08
gi|24308354 hypothetical protein LOC89927 isoform 1 [Homo sapiens] 57 6e-08
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 57 8e-08
gi|150170670 piccolo isoform 2 [Homo sapiens] 57 8e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 57 8e-08
gi|171906559 peripheral benzodiazepine receptor-associated prote... 57 8e-08
gi|195947369 junction-mediating and regulatory protein [Homo sap... 56 1e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 56 1e-07
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 56 1e-07
gi|93102364 SWAP-70 protein [Homo sapiens] 55 2e-07
gi|81295809 pericentrin [Homo sapiens] 55 2e-07
>gi|118918413 MICAL C-terminal like [Homo sapiens]
Length = 695
Score = 1382 bits (3577), Expect = 0.0
Identities = 695/695 (100%), Positives = 695/695 (100%)
Query: 1 MSPPKDPSPSLPLPSSSSHSSSPPSSSSTSVSGNAPDGSSPPQMTASEPLSQVSRGHPSP 60
MSPPKDPSPSLPLPSSSSHSSSPPSSSSTSVSGNAPDGSSPPQMTASEPLSQVSRGHPSP
Sbjct: 1 MSPPKDPSPSLPLPSSSSHSSSPPSSSSTSVSGNAPDGSSPPQMTASEPLSQVSRGHPSP 60
Query: 61 PTPNFRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLSDPAEMTSDECQPAEAP 120
PTPNFRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLSDPAEMTSDECQPAEAP
Sbjct: 61 PTPNFRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLSDPAEMTSDECQPAEAP 120
Query: 121 LGDIGSNHRDPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLVKEKLGLKK 180
LGDIGSNHRDPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLVKEKLGLKK
Sbjct: 121 LGDIGSNHRDPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLVKEKLGLKK 180
Query: 181 LVLTQEQKTMLLDWNDSIPESVHLKAGERISQKSAENGRGGRVLKPVRPLLLPRAAGEPL 240
LVLTQEQKTMLLDWNDSIPESVHLKAGERISQKSAENGRGGRVLKPVRPLLLPRAAGEPL
Sbjct: 181 LVLTQEQKTMLLDWNDSIPESVHLKAGERISQKSAENGRGGRVLKPVRPLLLPRAAGEPL 240
Query: 241 PTQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQES 300
PTQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQES
Sbjct: 241 PTQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQES 300
Query: 301 KTLPAQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRPSKVFPALR 360
KTLPAQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRPSKVFPALR
Sbjct: 301 KTLPAQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRPSKVFPALR 360
Query: 361 SPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDI 420
SPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDI
Sbjct: 361 SPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDI 420
Query: 421 RDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNF 480
RDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNF
Sbjct: 421 RDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNF 480
Query: 481 PLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKR 540
PLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKR
Sbjct: 481 PLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKR 540
Query: 541 LYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKL 600
LYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKL
Sbjct: 541 LYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKL 600
Query: 601 MRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQR 660
MRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQR
Sbjct: 601 MRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQR 660
Query: 661 DKLVDSLEEQRIREKAEDQHFESFVFSRGCQLSRT 695
DKLVDSLEEQRIREKAEDQHFESFVFSRGCQLSRT
Sbjct: 661 DKLVDSLEEQRIREKAEDQHFESFVFSRGCQLSRT 695
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 205 bits (522), Expect = 1e-52
Identities = 162/479 (33%), Positives = 244/479 (50%), Gaps = 50/479 (10%)
Query: 247 QEKMGTPAE---QAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQESKTL 303
QEK TP + + R+ P K RL A LE L + G E+K L
Sbjct: 1540 QEKFFTPPSCWPRPEKPRHPPLAKENGRLPA------LEGTLQPQKRGLPL-VSAEAKEL 1592
Query: 304 PAQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSPPDPALR-THSLPNRPSKVFPALRSP 362
+ K+ + +D R Q + P R S P++ + P +
Sbjct: 1593 AEERMRAREKSVKSQALRDAMARQLSRMQQMELASGAPRPRKASSAPSQGKERRPDSPTR 1652
Query: 363 PCSKIEDVPTLLEKVSLQENF--------PD--------ASKPPKKRISLFSSLRLKDKS 406
P + + PTL + + +E PD +S KKR SLFS R K
Sbjct: 1653 PTLRGSEEPTLKHEATSEEVLSPPSDSGGPDGSFTSSEGSSGKSKKRSSLFSPRRNK--- 1709
Query: 407 FESFLQESRQRKDIRDLFGSPKRKVLPEDSAQAL---EKLLQPFKSTSLRQAAPPPPPPP 463
+E + + + R P +L E +A+ + + +K ++A P
Sbjct: 1710 -----KEKKSKGEGRPP-EKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKA--DDKSCP 1761
Query: 464 PPPPPPPTAGGADSKNFPL-RAQVT-EASSSASSTSSSSADEEFDPQLSLQLKEKKTLRR 521
P T + P+ RA++ S S S S+D+ + +E +T
Sbjct: 1762 STPSSGATVDSGKHRVLPVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRREPRTYTE 1821
Query: 522 R-------KKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRG 574
++++KA ++ KQEELKRL++AQ IQRQL++VEERQR E +GV +EKALRG
Sbjct: 1822 EELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQVEERQRRLEERGVAVEKALRG 1881
Query: 575 EADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKE 634
EA G +D+ +L+QEWFKLV EKN ++RYESEL+I A+ELELED QSRL+Q+LRE+M E
Sbjct: 1882 EAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQELRERMAVE 1941
Query: 635 ESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESFVFSRGCQLS 693
+ K E++L+EE+++ E+++V+EQRD LV LEEQR+RE+ ED+ E+ + S+G L+
Sbjct: 1942 DHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLREREEDKDLEAAMLSKGFSLN 2000
Score = 37.4 bits (85), Expect = 0.047
Identities = 58/242 (23%), Positives = 89/242 (36%), Gaps = 25/242 (10%)
Query: 256 QAQGERNVPPP-KSPLRLIANAIRRS--LEPLLSNSEGGKKAWAKQESKTLPAQACTRSF 312
Q E VP P +SP+R + S L PL S+ K + S +A RS
Sbjct: 1265 QPSTEATVPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKD--RLGSPLAVDEALRRSD 1322
Query: 313 SLRKTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRPSKVFPALRSPPCSKIEDVPT 372
+ + + S G P+P+ T + K + +SP +
Sbjct: 1323 LVEEFWMKSAEIRRSLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLH---- 1378
Query: 373 LLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVL 432
LL+ +S+ + KP + +SL + D+ S +E R+ S L
Sbjct: 1379 LLKPLSIPKRL-GLPKPEGEPLSLPTPRSPSDRELRSAQEERRE-------LSSSSGLGL 1430
Query: 433 PEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSS 492
S+ Q F ++ PP PPPPPPP A LR ++ EA +
Sbjct: 1431 HGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEPA--------TLRRKLREAEPN 1482
Query: 493 AS 494
AS
Sbjct: 1483 AS 1484
Score = 31.2 bits (69), Expect = 3.4
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 13/94 (13%)
Query: 426 SPKRKVLPE----------DSAQALEKLLQPFKS--TSLRQAAPPPPPPPPPPPPPPTAG 473
SP+ ++ PE D+ L+ + P +S +L +A P P P P PP A
Sbjct: 1192 SPEERLFPEPLLPKEKPKADAPSDLKAVHSPIRSQPVTLPEARTPVSPGSPQPQPPVAAS 1251
Query: 474 GADSKNFPLRAQVTEASSSASSTSSSSADEEFDP 507
P+ +Q + S+ A+ S + + F P
Sbjct: 1252 TPPPSPLPICSQ-PQPSTEATVPSPTQSPIRFQP 1284
>gi|205360947 microtubule associated monoxygenase, calponin and LIM
domain containing 1 isoform 1 [Homo sapiens]
Length = 1067
Score = 119 bits (298), Expect = 9e-27
Identities = 81/238 (34%), Positives = 126/238 (52%), Gaps = 20/238 (8%)
Query: 459 PPPPPPPPPPPPTAGGADSKN----------FPLRA-QVTEASSSASSTSSSSADEE--- 504
P P PPP PP + A +++ P+++ Q A S S++EE
Sbjct: 823 PDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEEEED 882
Query: 505 ----FDPQLSLQL--KEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQ 558
D + +LQ K T+ + + + K+EE+KR KAQ IQR+L E+E
Sbjct: 883 VPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAAL 942
Query: 559 RASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELED 618
R E +GV+LE ALR ++ S Q + + + +LV +KN L+ E+EL+I QEL LE+
Sbjct: 943 RELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEE 1002
Query: 619 HQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKA 676
Q +L+Q+LR M +EE+ K D E +V +L+ ++ QRD L+ EE+R+ E A
Sbjct: 1003 KQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSELA 1060
>gi|226530313 microtubule associated monoxygenase, calponin and LIM
domain containing 1 isoform 2 [Homo sapiens]
Length = 981
Score = 119 bits (298), Expect = 9e-27
Identities = 81/238 (34%), Positives = 126/238 (52%), Gaps = 20/238 (8%)
Query: 459 PPPPPPPPPPPPTAGGADSKN----------FPLRA-QVTEASSSASSTSSSSADEE--- 504
P P PPP PP + A +++ P+++ Q A S S++EE
Sbjct: 737 PDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEEEED 796
Query: 505 ----FDPQLSLQL--KEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQ 558
D + +LQ K T+ + + + K+EE+KR KAQ IQR+L E+E
Sbjct: 797 VPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAAL 856
Query: 559 RASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELED 618
R E +GV+LE ALR ++ S Q + + + +LV +KN L+ E+EL+I QEL LE+
Sbjct: 857 RELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEE 916
Query: 619 HQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKA 676
Q +L+Q+LR M +EE+ K D E +V +L+ ++ QRD L+ EE+R+ E A
Sbjct: 917 KQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSELA 974
>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
Length = 904
Score = 106 bits (264), Expect = 8e-23
Identities = 58/151 (38%), Positives = 88/151 (58%), Gaps = 2/151 (1%)
Query: 545 QAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYE 604
+ IQRQL+++E R A E++GV LEK LR A G E L+ +WF L+ EK L+R E
Sbjct: 738 EEIQRQLQDIERRLDALELRGVELEKRLR--AAEGDDAEDSLMVDWFWLIHEKQLLLRQE 795
Query: 605 SELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLV 664
SEL+ ++ LE+ Q +E +LR M K E+ K ++ EQE+ + + + R +V
Sbjct: 796 SELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIV 855
Query: 665 DSLEEQRIREKAEDQHFESFVFSRGCQLSRT 695
DSL+E R+RE+ EDQ + G Q ++
Sbjct: 856 DSLDEDRLREQEEDQMLRDMIEKLGLQRKKS 886
Score = 30.4 bits (67), Expect = 5.8
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 6/44 (13%)
Query: 459 PPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSAD 502
PP P P P P GGA R + + S+SSTS+++ D
Sbjct: 365 PPSAPDPRPATPQGGGAP------RVAAPQTTLSSSSTSAATVD 402
Score = 30.0 bits (66), Expect = 7.5
Identities = 99/417 (23%), Positives = 146/417 (35%), Gaps = 63/417 (15%)
Query: 3 PPKDPS--PSLPLPSSSSHSSSPP---SSSSTSVSGNAPDGSSPP------------QMT 45
PP P P+ P + ++P SSSSTS + P +P Q +
Sbjct: 365 PPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQARNKFFQTS 424
Query: 46 ASEPLSQVSRGHPSP-----------PTPNFRRRAVAQGAPREIPLYLPHHPKPEWAEYC 94
A P + +S P+P NF ++A++ A E P P P A
Sbjct: 425 AVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALS--ALEEAGAPAPGRPSPATAAVP 482
Query: 95 LVSPGEDGLSDPAEMTSDECQPAEAPLGDIGSNHRDPHPIWGKDRSWTGQELSPLAGEDR 154
P + + A + Q + + + S P P+ S + P AG
Sbjct: 483 SSQPKTE--APQASPLAKPLQSSSPRVLGLPSRMEPPAPL--STSSTSQASALPPAGRRN 538
Query: 155 EKGSTGARKEEEGGPVLVKEKLGL-KKLVLTQEQKTMLLDWNDSIPESVHLKAGERISQK 213
S+G + G + + K LTQ+ T L + + P AG R + K
Sbjct: 539 LAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDGP------AGWRANLK 592
Query: 214 SAE-NGRGGRVLKPVRPLLL--PRAAGEPLPTQ---RGAQEKMGTPAEQAQGERNVPP-P 266
+ R LKP P L PRA P G+ TP + R P P
Sbjct: 593 PVDRRSPAERTLKPKEPRALAEPRAGEAPRKVSGSFAGSVHITLTPVRPDRTPRPASPGP 652
Query: 267 KSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQESKTLPAQ-ACTRSFSLRKTNSNKDGDQ 325
P R + RR L + S W + E P Q A +S+ K K Q
Sbjct: 653 SLPARSPSPPRRRRL--AVPASLDVCDNWLRPEP---PGQEARVQSW---KEEEKKPHLQ 704
Query: 326 HSPGRNQSSAFSPPDPALRTHSLPNRPSKVFPALRSPP--CSKIEDVPTLLEKVSLQ 380
PGR S A P P S P ++ P SP +++D+ L+ + L+
Sbjct: 705 GKPGRPLSPANVPALPGETVTS----PVRLHPDYLSPEEIQRQLQDIERRLDALELR 757
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 97.8 bits (242), Expect = 3e-20
Identities = 126/520 (24%), Positives = 218/520 (41%), Gaps = 73/520 (14%)
Query: 208 ERISQKSAENGRGGRVLKPVRPLLLPRAAGEPLPTQRGAQEKMGTPAEQAQGERNVPPPK 267
E+ S NGR + L +P+ G P P++ GTPA P K
Sbjct: 332 EQAGSSSLVNGR-------LHELPVPKPRGTPKPSE-------GTPA----------PRK 367
Query: 268 SP--LRLIANAIRRSLEPLLSNSEGGKKAWAKQE-----SKTLPAQACTRSFSLRKTNSN 320
P + L+ ++ PL +S G + ++ ++ + + T S + N
Sbjct: 368 DPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPF 427
Query: 321 KDGDQHSPGRNQSSAFSPPDPAL-RTHSLPNR-------------PSKVFPALRSPPCSK 366
++ ++ ++ PAL S P +K PA R+P S
Sbjct: 428 EEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSAS- 486
Query: 367 IEDVPTLLEKVSLQENFPDASKP-PKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLF- 424
P L L + P ++ P P + SS + L+ K +
Sbjct: 487 ----PLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAV 542
Query: 425 ---GSPKRKV-LPEDSAQALEKLLQPFKSTSLRQAAPPPPP----PPPPPPPPPTAGGAD 476
G+P V L +S+ A L + + QA+P P P P P +G
Sbjct: 543 HAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATP 602
Query: 477 SKNFPL--RAQVTEASSSASS--TSSSSADEEFD--PQLSLQLKEKKTLRRRKKLEKAMK 530
+ + R+ V SS+ SS + F+ P + KK + K +
Sbjct: 603 TPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAP 662
Query: 531 ----QLVKQE-ELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQ 585
L+K++ + + + I +++ +E R A E +GV LE+ LRG + G +D+
Sbjct: 663 GHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVLLEEKLRGGLNEGREDD-- 720
Query: 586 LLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNE 645
+L +WFKL+ EK+ L+R ESEL+ + ++ LE Q+ +E +LR + K E E+D
Sbjct: 721 MLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAR 780
Query: 646 EQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESFV 685
E+ + EL+ +IEQR+ +++ L+E R RE+ ED+ E+ +
Sbjct: 781 EKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMI 820
>gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens]
Length = 1160
Score = 90.5 bits (223), Expect = 5e-18
Identities = 56/183 (30%), Positives = 99/183 (54%), Gaps = 4/183 (2%)
Query: 504 EFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYK--AQAIQRQLEEVEERQRAS 561
E Q S+Q KK + + + ++ + E L + +K +Q + +L +E Q+
Sbjct: 958 EMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQI 1017
Query: 562 EIQGVRLEKALRGEADSG--TQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDH 619
+ + +EK LR D+G T++E ++QEWF LV +KN L+R ++L ++ +E +LE
Sbjct: 1018 DTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERR 1077
Query: 620 QSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQ 679
L ++LR + E+ QK E EQ + EL+ ++ +RD LV L+ Q + + ED+
Sbjct: 1078 YELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDE 1137
Query: 680 HFE 682
H E
Sbjct: 1138 HLE 1140
>gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens]
Length = 1160
Score = 90.5 bits (223), Expect = 5e-18
Identities = 56/183 (30%), Positives = 99/183 (54%), Gaps = 4/183 (2%)
Query: 504 EFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYK--AQAIQRQLEEVEERQRAS 561
E Q S+Q KK + + + ++ + E L + +K +Q + +L +E Q+
Sbjct: 958 EMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQI 1017
Query: 562 EIQGVRLEKALRGEADSG--TQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDH 619
+ + +EK LR D+G T++E ++QEWF LV +KN L+R ++L ++ +E +LE
Sbjct: 1018 DTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERR 1077
Query: 620 QSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQ 679
L ++LR + E+ QK E EQ + EL+ ++ +RD LV L+ Q + + ED+
Sbjct: 1078 YELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDE 1137
Query: 680 HFE 682
H E
Sbjct: 1138 HLE 1140
>gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]
Length = 1196
Score = 90.5 bits (223), Expect = 5e-18
Identities = 56/183 (30%), Positives = 99/183 (54%), Gaps = 4/183 (2%)
Query: 504 EFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYK--AQAIQRQLEEVEERQRAS 561
E Q S+Q KK + + + ++ + E L + +K +Q + +L +E Q+
Sbjct: 994 EMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQI 1053
Query: 562 EIQGVRLEKALRGEADSG--TQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDH 619
+ + +EK LR D+G T++E ++QEWF LV +KN L+R ++L ++ +E +LE
Sbjct: 1054 DTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERR 1113
Query: 620 QSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQ 679
L ++LR + E+ QK E EQ + EL+ ++ +RD LV L+ Q + + ED+
Sbjct: 1114 YELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDE 1173
Query: 680 HFE 682
H E
Sbjct: 1174 HLE 1176
Score = 32.3 bits (72), Expect = 1.5
Identities = 39/188 (20%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Query: 507 PQLSLQLKEKKTLRRRKKLEKAMKQLVKQEE--LKRLYKAQAIQRQLEEVEERQRASEIQ 564
P + QL +++ RR++L + +QL+ + +K + E+++ER +AS +
Sbjct: 812 PFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDE 871
Query: 565 GVRLEKALRGEADS----GTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQ 620
+E E G DE L+ + +KL+ + + L LE++
Sbjct: 872 NDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKL-----LEVQPQV 926
Query: 621 SRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQH 680
+ +K + E S++D K E ++ TE +Q +R + + K + Q
Sbjct: 927 ANSPSSAAQKAVTESSEQDMKSGTE--DLRTERLQKTTERFRNPVVFSKDSTVRKTQLQS 984
Query: 681 FESFVFSR 688
F ++ +R
Sbjct: 985 FSQYIENR 992
>gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]
Length = 1231
Score = 90.5 bits (223), Expect = 5e-18
Identities = 56/183 (30%), Positives = 99/183 (54%), Gaps = 4/183 (2%)
Query: 504 EFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYK--AQAIQRQLEEVEERQRAS 561
E Q S+Q KK + + + ++ + E L + +K +Q + +L +E Q+
Sbjct: 1029 EMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQI 1088
Query: 562 EIQGVRLEKALRGEADSG--TQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDH 619
+ + +EK LR D+G T++E ++QEWF LV +KN L+R ++L ++ +E +LE
Sbjct: 1089 DTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERR 1148
Query: 620 QSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQ 679
L ++LR + E+ QK E EQ + EL+ ++ +RD LV L+ Q + + ED+
Sbjct: 1149 YELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDE 1208
Query: 680 HFE 682
H E
Sbjct: 1209 HLE 1211
Score = 32.3 bits (72), Expect = 1.5
Identities = 39/188 (20%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Query: 507 PQLSLQLKEKKTLRRRKKLEKAMKQLVKQEE--LKRLYKAQAIQRQLEEVEERQRASEIQ 564
P + QL +++ RR++L + +QL+ + +K + E+++ER +AS +
Sbjct: 847 PFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDE 906
Query: 565 GVRLEKALRGEADS----GTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQ 620
+E E G DE L+ + +KL+ + + L LE++
Sbjct: 907 NDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKL-----LEVQPQV 961
Query: 621 SRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQH 680
+ +K + E S++D K E ++ TE +Q +R + + K + Q
Sbjct: 962 ANSPSSAAQKAVTESSEQDMKSGTE--DLRTERLQKTTERFRNPVVFSKDSTVRKTQLQS 1019
Query: 681 FESFVFSR 688
F ++ +R
Sbjct: 1020 FSQYIENR 1027
>gi|150378549 tangerin [Homo sapiens]
Length = 1523
Score = 84.0 bits (206), Expect = 4e-16
Identities = 71/242 (29%), Positives = 109/242 (45%), Gaps = 41/242 (16%)
Query: 455 AAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLK 514
AA P P P P PPTA ADS+ P SS EE P
Sbjct: 1310 AAEGQAPDPSPAPGPPTA--ADSQQPP---------------GGSSPSEEPPPSPG---- 1348
Query: 515 EKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRG 574
E+ L+R + +Q + +L+ +E+ QR + + +E LR
Sbjct: 1349 EEAGLQRFQDT------------------SQYVCAELQALEQEQRQIDGRAAEVEMQLRS 1390
Query: 575 EADSGTQ--DEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKML 632
+SG E L+QEWF LV +KN L+R + +L ++ +E +LE L ++LR +
Sbjct: 1391 LMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFELLSRELRAMLA 1450
Query: 633 KEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESFVFSRGCQL 692
E+ QK + EQ + EL+ ++ QRD+LV L+ + ED+ E + R +L
Sbjct: 1451 IEDWQKTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLERGLEQRRRKL 1510
Query: 693 SR 694
SR
Sbjct: 1511 SR 1512
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 66.6 bits (161), Expect = 7e-11
Identities = 160/705 (22%), Positives = 269/705 (38%), Gaps = 120/705 (17%)
Query: 8 SPSLPLPSSSSHSSSPPSSSSTSVS--GNAPDGSSPPQMTASEPLSQVSRGHPSP----P 61
+PS P P S + + P + T G S Q A + ++Q+ P P P
Sbjct: 140 APSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQ-NAEQHVTQLMSTEPLPRTLSP 198
Query: 62 TPNFRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLSDP-AEMTSDECQPAEAP 120
TP +QG P P K E VS DP + ++
Sbjct: 199 TPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLR 258
Query: 121 LGDIGSNHRDPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEG------GPVLVKE 174
+ + RD D W + L+P+ D TG+R + + P
Sbjct: 259 IAQVSPGPRDSPAF--PDSPWRERVLAPIL-PDNFSTPTGSRTDSQSVRHSPIAPSSPSP 315
Query: 175 KLGLKKLVLTQEQKTMLLDWNDSIPESVHLKAGERISQKSAEN-GRGGRVLKPVRPLLLP 233
++ +K L +Q ESV +A R+++K+AE GR+ + L
Sbjct: 316 QVLAQKYSLVAKQ------------ESVVRRASRRLAKKTAEEPAASGRI---ICHSYLE 360
Query: 234 RAAGEPLPTQRGAQEKMGTPAEQAQ----GERNVPP-------PKSPLRLIANAIRRSLE 282
R +P + G+++K P E+A+ E VP P + IAN+ +
Sbjct: 361 RLLNVEVPQKVGSEQK--EPPEEAEPVAAAEPEVPENNGNNSWPHNDTE-IANSTPNP-K 416
Query: 283 PLLSNSEGGKKAWAKQESKT-------LPAQACTRSFSLRKTNSNKDGDQHSPGRNQSSA 335
P S+ E + +QE+KT P Q+ R S ++ S D +QH +
Sbjct: 417 PAASSPE--TPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHL----EDEE 470
Query: 336 FSPPDPALRTHSLPNRPSKVFPALRSPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRIS 395
PP +T S P SKV LR T L V + + P+ +
Sbjct: 471 LQPPRS--KTPSSPCPASKVVRPLR-----------TFLHTVQRNQMLMTPTSAPRSVMK 517
Query: 396 LF----SSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVLPEDSAQALE--KLLQPFKS 449
F + LR+ K E E+ +RK+ + +R+ + ED + LE KL + +
Sbjct: 518 SFIKRNTPLRMDPKEKERQRLENLRRKEEAEQL---RRQKVEEDKRRRLEEVKLKREERL 574
Query: 450 TSLRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQL 509
+ QA Q+ E + DE+ +
Sbjct: 575 RKVLQARERVE------------------------QMKEEKKKQIEQKFAQIDEKTEKAK 610
Query: 510 SLQLKEKKTLRRR--KKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVR 567
+L E+K ++ KK+E+ + ++EE +RL Q + + E Q+ E + R
Sbjct: 611 EERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 670
Query: 568 LEKALRGE--ADSGTQDEA-QLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLE 624
L KA + A+ Q+ Q +E + E+ + R E E + QE E + + E
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
Query: 625 QKLREK-----MLKEESQKD--EKDLNEEQEVFTELMQVIEQRDK 662
++L+E+ + KE+ Q++ EK EEQ+ E Q+ E+++K
Sbjct: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAE-RQLQEEQEK 774
Score = 42.0 bits (97), Expect = 0.002
Identities = 69/341 (20%), Positives = 137/341 (40%), Gaps = 43/341 (12%)
Query: 346 HSLPNRPSKVFPALRSP-PCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKD 404
+S P+ +++ + +P P + + P+ ++ + + +PP+ S R K
Sbjct: 399 NSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQ-------SARRK- 450
Query: 405 KSFESFLQESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPP 464
+S++ + E + + + D P R P A K+++P + T L P
Sbjct: 451 RSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPA-SKVVRPLR-TFLHTVQRNQMLMTP 508
Query: 465 PPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKK 524
P +N PLR E +E +L+ KE+ RR+K
Sbjct: 509 TSAPRSVMKSFIKRNTPLRMDPKE--------------KERQRLENLRRKEEAEQLRRQK 554
Query: 525 LEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEA 584
+E+ ++ +++ +LKR + + + + E VE+ + EK + E DE
Sbjct: 555 VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKE---------EKKKQIEQKFAQIDEK 605
Query: 585 QLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLN 644
+ +L EK K ++ + + E+ RL +E+ + + +K
Sbjct: 606 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 665
Query: 645 EEQEVF---TELMQVIEQRDKLVDSLEEQRIREKAEDQHFE 682
EEQE E ++ EQR+ +E+R +E+ E + E
Sbjct: 666 EEQERLRKAAEAKRLAEQRE------QERREQERREQERRE 700
Score = 32.3 bits (72), Expect = 1.5
Identities = 17/67 (25%), Positives = 38/67 (56%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASE 562
E + LQ +EK ++++L++ +++ K+EE +RL + Q + Q ++ +E AS+
Sbjct: 725 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
Query: 563 IQGVRLE 569
V ++
Sbjct: 785 ALNVTVD 791
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 66.2 bits (160), Expect = 9e-11
Identities = 161/708 (22%), Positives = 272/708 (38%), Gaps = 122/708 (17%)
Query: 8 SPSLPLPSSSSHSSSPPSSSSTSVS--GNAPDGSSPPQMTASEPLSQVSRGHPSP----P 61
+PS P P S + + P + T G S Q A + ++Q+ P P P
Sbjct: 140 APSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQ-NAEQHVTQLMSTEPLPRTLSP 198
Query: 62 TPNFRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLSDP-AEMTSDECQPAEAP 120
TP +QG P P K E VS DP + ++
Sbjct: 199 TPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLR 258
Query: 121 LGDIGSNHRDPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEG------GPVLVKE 174
+ + RD D W + L+P+ D TG+R + + P
Sbjct: 259 IAQVSPGPRDSPAF--PDSPWRERVLAPIL-PDNFSTPTGSRTDSQSVRHSPIAPSSPSP 315
Query: 175 KLGLKKLVLTQEQKTMLLDWNDSIPESVHLKAGERISQKSAEN-GRGGRVLKPVRPLLLP 233
++ +K L +Q ESV +A R+++K+AE GR+ + L
Sbjct: 316 QVLAQKYSLVAKQ------------ESVVRRASRRLAKKTAEEPAASGRI---ICHSYLE 360
Query: 234 RAAGEPLPTQRGAQEKMGTPAEQAQ----GERNVPP-------PKSPLRLIANAIRRSLE 282
R +P + G+++K P E+A+ E VP P + IAN+ +
Sbjct: 361 RLLNVEVPQKVGSEQK--EPPEEAEPVAAAEPEVPENNGNNSWPHNDTE-IANSTPNP-K 416
Query: 283 PLLSNSEGGKKAWAKQESKT-------LPAQACTRSFSLRKTNSNKDGDQHSPGRNQSSA 335
P S+ E + +QE+KT P Q+ R S ++ S D +QH +
Sbjct: 417 PAASSPE--TPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHL----EDEE 470
Query: 336 FSPPDPALRTHSLPNRPSKVFPALRSPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRIS 395
PP +T S P SKV LR T L V + + P+ +
Sbjct: 471 LQPPRS--KTPSSPCPASKVVRPLR-----------TFLHTVQRNQMLMTPTSAPRSVMK 517
Query: 396 LF----SSLRLKDKSFESFLQESRQRKDI---RDLFGSPKRKVLPEDSAQALE--KLLQP 446
F + LR+ K SF+++ RQR + ++ +R+ + ED + LE KL +
Sbjct: 518 SFIKRNTPLRMDPKC--SFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE 575
Query: 447 FKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADEEFD 506
+ + QA Q+ E + DE+ +
Sbjct: 576 ERLRKVLQARERVE------------------------QMKEEKKKQIEQKFAQIDEKTE 611
Query: 507 PQLSLQLKEKKTLRRR--KKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQ 564
+L E+K ++ KK+E+ + ++EE +RL Q + + E Q+ E +
Sbjct: 612 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE 671
Query: 565 GVRLEKALRGE--ADSGTQDEA-QLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQS 621
RL KA + A+ Q+ Q +E + E+ + R E E + QE E +
Sbjct: 672 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 731
Query: 622 RLEQKLREK-----MLKEESQKD--EKDLNEEQEVFTELMQVIEQRDK 662
+ E++L+E+ + KE+ Q++ EK EEQ+ E Q+ E+++K
Sbjct: 732 QAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAE-RQLQEEQEK 778
Score = 48.1 bits (113), Expect = 3e-05
Identities = 68/342 (19%), Positives = 131/342 (38%), Gaps = 23/342 (6%)
Query: 352 PSKVFPALRSPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFL 411
P KV + PP E P + + EN + S P S+ K +
Sbjct: 368 PQKVGSEQKEPP---EEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPET 424
Query: 412 QESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPT 471
+ Q++ D P+ P SA+ Q Q PP P +
Sbjct: 425 PSAGQQEAKTDQADGPRE---PPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSS 481
Query: 472 AGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQ 531
A PLR + + + +SA + +K LR K K+
Sbjct: 482 PCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSV---MKSFIKRNTPLRMDPKCSFVEKE 538
Query: 532 LVKQEELKRLYKAQAIQRQLEEVEERQRASEI---QGVRLEKAL--RGEADSGTQDEAQL 586
+ E L+R +A+ ++RQ E ++R+R E+ + RL K L R + +++ +
Sbjct: 539 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 598
Query: 587 LQEWFKLVLEKNKLMRYE---------SELLIMAQELELEDHQSRLEQKLREKMLKEESQ 637
+++ F + EK + + E +E+E Q ++LR +EE +
Sbjct: 599 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 658
Query: 638 KDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQ 679
+ ++ L +++E E ++ + +L + E++R ++ +Q
Sbjct: 659 RHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 700
Score = 32.3 bits (72), Expect = 1.5
Identities = 17/67 (25%), Positives = 38/67 (56%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASE 562
E + LQ +EK ++++L++ +++ K+EE +RL + Q + Q ++ +E AS+
Sbjct: 729 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 788
Query: 563 IQGVRLE 569
V ++
Sbjct: 789 ALNVTVD 795
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 64.3 bits (155), Expect = 4e-10
Identities = 79/340 (23%), Positives = 158/340 (46%), Gaps = 40/340 (11%)
Query: 365 SKIEDVPTLLEKVSLQENFPDASKPP----KKRISLFSSLRLKDKSFESFLQESRQRKDI 420
+ ++ + TL ++V QEN K K++ +L +S K+ E + ++ + I
Sbjct: 276 TSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSE--KEALQEQLDERLQELEKI 333
Query: 421 RDLFGSPKRKVLPE--DSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSK 478
+DL + K K++ + D+ +E+L Q K + + T + +
Sbjct: 334 KDLHMAEKTKLITQLRDAKNLIEQLEQD-KGMVIAETKRQMHE---------TLEMKEEE 383
Query: 479 NFPLRAQVTEASSSASST------SSSSADEEFDPQLSLQLKEKKTLRRRK-KLEKAMKQ 531
LR+++ + ++ S +A EE + LS K ++ R+ K ++++ +K
Sbjct: 384 IAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKT 443
Query: 532 LVKQEELKRLYKAQAIQRQLEEVEE-RQRASEIQGVRLEKALRGEADSGTQDEAQLL--- 587
+ K E +R+ Q + R +EV + +++SE Q +L+K E Q+ + L
Sbjct: 444 IEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTR 503
Query: 588 ----QEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDL 643
QE K+ LEK+ +SE L ++QE E ++ + E +L++K + ES+ +DL
Sbjct: 504 EREFQEQMKVALEKS-----QSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDL 558
Query: 644 NEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFES 683
+E E + +++E L SL+E + + K H E+
Sbjct: 559 QQEAETYR--TRILELESSLEKSLQENKNQSKDLAVHLEA 596
Score = 40.8 bits (94), Expect = 0.004
Identities = 47/216 (21%), Positives = 101/216 (46%), Gaps = 32/216 (14%)
Query: 492 SASSTSSSSADEEFDPQLSLQLKE-KKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQ 550
SA S +EE++ + Q K+ +K ++ K++++ +K+ + +E K + + +
Sbjct: 932 SAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALE 991
Query: 551 LEEVEERQRASEIQGVRLEKALRGEA----DSGTQDEAQLLQEWFKLVLEK-----NKLM 601
L + E++ A ++ + A +A ++ +++ + L E + L K +
Sbjct: 992 LSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKL 1051
Query: 602 RYESELLIMAQELELEDHQ---SRLEQKL------REKM------LKEESQKDEKDLNEE 646
++E L E++L++ + + L+QK+ +E+M LKEE K + LNE
Sbjct: 1052 NQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNEL 1111
Query: 647 QEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFE 682
QE ++Q+ V+SL + + KA + E
Sbjct: 1112 QE-------QLKQKSAHVNSLAQDETKLKAHLEKLE 1140
Score = 37.7 bits (86), Expect = 0.036
Identities = 40/166 (24%), Positives = 77/166 (46%), Gaps = 17/166 (10%)
Query: 490 SSSASSTSSSSADEEFDPQL--SLQLKEKKTLRRRKKLEKAMKQLV-KQEELKRLYKAQA 546
SS+AS S D E + + S L +++ ++R +++E+++ K EL Y Q
Sbjct: 109 SSTASFDPPSDMDSEAEDLVGNSDSLNKEQLIQRLRRMERSLSSYRGKYSELVTAY--QM 166
Query: 547 IQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESE 606
+QR+ ++++ S+ + +R LR E Q + L +E+ + EK++ +
Sbjct: 167 LQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISV--- 223
Query: 607 LLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTE 652
L+ S L+Q+LR + + K L + EVFT+
Sbjct: 224 ---------LQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTK 260
Score = 35.0 bits (79), Expect = 0.23
Identities = 39/184 (21%), Positives = 82/184 (44%), Gaps = 40/184 (21%)
Query: 523 KKLEKAMKQLVKQEEL------KRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEA 576
++ EKA+K + Q EL K L + QA LE + ++ E+Q + +
Sbjct: 748 QRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE-ADIKRSEGELQQASAKLDVFQSY 806
Query: 577 DSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQEL---------------------- 614
S T ++ + +E +L + KL+ E+E +++ +++
Sbjct: 807 QSATHEQTKAYEE--QLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQ 864
Query: 615 ----ELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQ 670
+LE S +EQK+ K L + + +D N+EQE + Q++ +++ ++ + E
Sbjct: 865 DLMQQLEKQNSEMEQKV--KSLTQVYESKLEDGNKEQE---QTKQILVEKENMILQMREG 919
Query: 671 RIRE 674
+ +E
Sbjct: 920 QKKE 923
Score = 34.7 bits (78), Expect = 0.31
Identities = 37/189 (19%), Positives = 87/189 (46%), Gaps = 17/189 (8%)
Query: 506 DPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQ-----LEEVEERQRA 560
D Q +LQ KE +K+++ LV+Q+E+ R+ + + L++++ R +
Sbjct: 1837 DVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKP 1896
Query: 561 SEIQGVRLEKALRGEADSG---TQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELEL- 616
+E+ E+ + + EAQ FKL + + + E++ + ++L +
Sbjct: 1897 TELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRML 1956
Query: 617 -EDHQSRLE-------QKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLE 668
++HQ LE Q+ EK+ +E+ + K + +++ E + Q+++ ++
Sbjct: 1957 RKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTI 2016
Query: 669 EQRIREKAE 677
++ I + E
Sbjct: 2017 KETINKAQE 2025
Score = 33.9 bits (76), Expect = 0.52
Identities = 43/228 (18%), Positives = 103/228 (45%), Gaps = 19/228 (8%)
Query: 477 SKNFPLRAQVTEASSSASSTSSSSADEEFDPQLS--LQLKEKKTLR--RRKKLEKAMKQL 532
+K F E S S+ + E Q + ++L++ T + + L + +K
Sbjct: 1492 NKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNY 1551
Query: 533 VKQEELKR---LYKAQAIQRQLEEVEERQRASEIQGVRLEK---ALRGEADSGTQDEAQL 586
+Q++++ + K Q Q EE + R + +E + + LE +++ E ++ ++
Sbjct: 1552 NQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKE---- 1607
Query: 587 LQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKL---REKMLKEESQKDEKDL 643
L+ V K + ++ + L +L + + + EQK+ ++++L + +K+E+
Sbjct: 1608 LEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYK 1667
Query: 644 NEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESFVFSRGCQ 691
+ +EL +++R++ V LEE+ + E E+ + R +
Sbjct: 1668 KGTESHLSELNTKLQEREREVHILEEK--LKSVESSQSETLIVPRSAK 1713
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 61.2 bits (147), Expect = 3e-09
Identities = 49/173 (28%), Positives = 87/173 (50%), Gaps = 7/173 (4%)
Query: 511 LQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEK 570
L+ E++ LRR ++ E+ +Q +++E+ R + + + Q EE E+Q E Q R E+
Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337
Query: 571 ALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREK 630
LR E + + + + QE + + + +R E E Q+L E R +Q RE+
Sbjct: 338 QLRREQEERREQQLRREQEEER----REQQLRREQEEERREQQLRREQQLRREQQLRREQ 393
Query: 631 MLKEESQ-KDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFE 682
L+ E Q + E+ L EQ++ E Q + + +L EE+R +K E + E
Sbjct: 394 QLRREQQLRREQQLRREQQLRRE--QQLRREQQLRREQEEERHEQKHEQERRE 444
Score = 58.2 bits (139), Expect = 3e-08
Identities = 52/180 (28%), Positives = 96/180 (53%), Gaps = 9/180 (5%)
Query: 506 DPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQG 565
+P+ + + +K R ++L++ +QL+++E KR + Q +RQ + +E Q+ E Q
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKR--RRQEWERQYRKKDELQQEEE-QL 1033
Query: 566 VRLEKALR--GEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRL 623
+R E+ R E + ++E +L QE +L+ E+ + R + + Q + E+ Q
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE---LERQYRKEEELQQEE 1090
Query: 624 EQKLREKMLKEESQKDEKDLNEEQEVFTELMQVI-EQRDKLVDSLEEQRIREKAEDQHFE 682
EQ LRE+ K Q+ E+ EE+E+ E Q++ E+R+K E++ RE+ E Q E
Sbjct: 1091 EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150
Score = 57.8 bits (138), Expect = 3e-08
Identities = 55/193 (28%), Positives = 96/193 (49%), Gaps = 17/193 (8%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKLEKAMK----------QLVKQEELKRLYKAQAIQRQL 551
+EE + L+E++ RRR++ E+ + QL+++E KR + Q +RQ
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR--RLQERERQY 1050
Query: 552 EEVEERQRASE-IQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIM 610
E EE Q+ E + G E R E + + E +L QE +L+ E+ + R +
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110
Query: 611 AQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVI-EQRDKLVDSLEE 669
+E EL+ + +L ++ REK ++E E+ EE+EV E Q++ E+ +K E
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQEL---ERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Query: 670 QRIREKAEDQHFE 682
++ RE+ E Q E
Sbjct: 1168 RQYREEEELQQEE 1180
Score = 56.6 bits (135), Expect = 8e-08
Identities = 56/195 (28%), Positives = 90/195 (46%), Gaps = 24/195 (12%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQE-ELKRLYKAQAIQRQLEEVEERQRA 560
D F + L+ +E+K +RR + + KQL+++E E KR + Q R+ E E+ +
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKR--RRQETDRKFREEEQLLQE 1347
Query: 561 SEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRY---ESELLIMAQELELE 617
E Q +R R E D ++E QE + LE+ + +R E + L Q+L +
Sbjct: 1348 REEQPLR-----RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQ 1402
Query: 618 DHQSRLEQKLREKMLKEESQ-----KDEKDLNEEQEV--------FTELMQVIEQRDKLV 664
+ + +L Q K +EE Q +D K EEQ+V F E Q + Q
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK 1462
Query: 665 DSLEEQRIREKAEDQ 679
EEQ ++E+ E Q
Sbjct: 1463 FREEEQLLQEREEQQ 1477
Score = 56.2 bits (134), Expect = 1e-07
Identities = 56/190 (29%), Positives = 94/190 (49%), Gaps = 35/190 (18%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEER----- 557
+E + +L +L+ ++ LRR + E+ +QL+K+EE KRL + + QR E EER
Sbjct: 522 QEEEERLQQRLRSEQQLRREQ--EERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 558 --------QRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLI 609
QR Q RLE+ L+ E + E + + +L R E E
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEER----------REQRLKREEPEEER 629
Query: 610 MAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEE 669
Q L+ E+ + R +Q+LR +E+ ++ E+ L E+E + +EQR K + EE
Sbjct: 630 RQQLLKSEEQEERRQQQLR----REQQERREQRLKREEEE-----ERLEQRLKR-EHEEE 679
Query: 670 QRIREKAEDQ 679
+R +E AE++
Sbjct: 680 RREQELAEEE 689
Score = 55.8 bits (133), Expect = 1e-07
Identities = 49/183 (26%), Positives = 92/183 (50%), Gaps = 13/183 (7%)
Query: 504 EFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEI 563
E + QL Q +++ + R + + +QL+++ E ++L++ + ++ LEE + +R
Sbjct: 1599 EDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQER- 1657
Query: 564 QGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMR--YESELLIMAQELE---LED 618
E+ LR + D ++E QLLQE + L + + R E E + QE E L++
Sbjct: 1658 -----EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQE 1712
Query: 619 HQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAED 678
Q Q+L K +EE + E + +EQ E + I + ++L EEQ++R + D
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETE--QEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 679 QHF 681
+ F
Sbjct: 1771 RKF 1773
Score = 53.9 bits (128), Expect = 5e-07
Identities = 50/181 (27%), Positives = 96/181 (53%), Gaps = 19/181 (10%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVK-QEELKRLYKAQAIQRQLEEVEERQRA 560
+E+ + L+E++ RRR++ E+ ++ K Q++ ++L + +R+ +E E++ R
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Query: 561 SEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQ 620
E E+ LR E E + QEW + +K++L + E +L L E +
Sbjct: 993 EEELQQEEEQLLREER------EKRRRQEWERQYRKKDELQQEEEQL------LREEREK 1040
Query: 621 SRLEQKLREKMLKEESQKDEKD-LNEEQEVFTELMQVIEQRDKLVDSL---EEQRIREKA 676
RL+++ R+ +EE Q++E+ L EE+E T Q +E++ + + L EEQ +RE+
Sbjct: 1041 RRLQERERQYREEEELQQEEEQLLGEERE--TRRRQELERQYRKEEELQQEEEQLLREEP 1098
Query: 677 E 677
E
Sbjct: 1099 E 1099
Score = 53.9 bits (128), Expect = 5e-07
Identities = 46/170 (27%), Positives = 84/170 (49%), Gaps = 14/170 (8%)
Query: 514 KEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALR 573
+E+ + R++ ++ + ++E+L+R + +A +R + EE+Q E R EK R
Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE---EREEKRRR 1331
Query: 574 GEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLK 633
E D ++E QLLQE E+ L R E + +EL HQ + + L E+
Sbjct: 1332 QETDRKFREEEQLLQE-----REEQPLRRQERDRKFREEELR---HQEQGRKFLEEEQRL 1383
Query: 634 EESQKDEKDLNEEQEVFTE--LMQVIEQRDKLVDSLEEQRIREKAEDQHF 681
+++ K L EEQ++ + Q+ + RD+ EEQ++ + D+ F
Sbjct: 1384 RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE-EEQQLSRQERDRKF 1432
Score = 53.1 bits (126), Expect = 8e-07
Identities = 53/211 (25%), Positives = 99/211 (46%), Gaps = 21/211 (9%)
Query: 483 RAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLV-------KQ 535
RA+ S F+P+ QL+E+ RRR+K ++ ++L KQ
Sbjct: 100 RARCDGKESLLQDRRQEEDQRRFEPR-DRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQ 158
Query: 536 EELK---RLYKAQAIQRQLEEVEERQ--RASEIQGVRLEKALRGEADSGTQDEAQL---- 586
E L+ R + + + RQ +E +ER+ RA E Q ++ +G DE QL
Sbjct: 159 ERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ----LQSCKGHETEEFPDEEQLRRRE 214
Query: 587 LQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEE 646
L E + E+ + R E + + +E E E + + E+ L+EE + +++L EE
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274
Query: 647 QEVFTELMQVIEQRDKLVDSLEEQRIREKAE 677
+E +L + +R++ + ++QR+R + +
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQ 305
Score = 53.1 bits (126), Expect = 8e-07
Identities = 46/191 (24%), Positives = 94/191 (49%), Gaps = 15/191 (7%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEEL-----KRLYKAQAIQRQLEEVEER 557
++ + QL + +EK+ L+ R++ + ++L ++EE + + Q ++RQ + EE
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 558 QRASE-IQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELEL 616
Q+ E + EK R E + ++E +L QE +L+ E+ + R + + Q E
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE---LERQYREE 1143
Query: 617 EDHQSRLEQKLREKMLKEESQ------KDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQ 670
E+ Q EQ LRE+ K Q ++E++L +E+E Q ++++ EE+
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
Query: 671 RIREKAEDQHF 681
++ + Q +
Sbjct: 1204 ELQRQKRKQRY 1214
Score = 52.8 bits (125), Expect = 1e-06
Identities = 48/169 (28%), Positives = 91/169 (53%), Gaps = 16/169 (9%)
Query: 511 LQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEK 570
L+L+E++ RR++ E+ +QL +++E +R Q ++RQ EE +QR Q +R E+
Sbjct: 489 LKLEEEE---RREQQERREQQLRREQEERR---EQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 571 ALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRL----EQK 626
R E ++E +L QE + +L R + E + E E Q RL E++
Sbjct: 543 EERREQLLKREEEKRLEQE-----RREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Query: 627 LREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREK 675
L +++ +EE ++ E++ EQ + E + E+R +L+ S E++ R++
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEE-ERRQQLLKSEEQEERRQQ 645
Score = 52.8 bits (125), Expect = 1e-06
Identities = 50/194 (25%), Positives = 96/194 (49%), Gaps = 17/194 (8%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEE------ 556
+E + +L + +EK+ + +++ + +QL ++EE +L + + +R+ +E E
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEE--QLLREEREKRRRQERERQYRKDK 964
Query: 557 --RQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVL-EKNKLMRYESELLIMAQE 613
+Q+ ++ G EK R E + ++E +L QE +L+ E+ K R E E Q
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE----RQY 1020
Query: 614 LELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVI--EQRDKLVDSLEEQR 671
+ ++ Q EQ LRE+ K Q+ E+ EE+E+ E Q++ E+ + LE Q
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 672 IREKAEDQHFESFV 685
+E+ Q E +
Sbjct: 1081 RKEEELQQEEEQLL 1094
Score = 52.0 bits (123), Expect = 2e-06
Identities = 48/190 (25%), Positives = 99/190 (52%), Gaps = 13/190 (6%)
Query: 502 DEEFDPQLSLQLKEKKT---LRRRKKLEKAMKQLVKQEELKR---LYKAQAIQRQLEEVE 555
+E + QL + +E++ LRR ++ E+ +QL ++++L+R L + Q ++R+ +
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR 403
Query: 556 ERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELE 615
E+Q E Q +R E+ LR E + E + ++ + + +L R + E L+
Sbjct: 404 EQQLRRE-QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE---RRDWLK 459
Query: 616 LEDHQSRLEQKLREKMLK--EESQKDEKDLNEEQEVFTELMQVIEQR-DKLVDSLEEQRI 672
E+ R EQ+ R++ LK +E ++ E+ L E+E E + EQ+ + + EQR+
Sbjct: 460 REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRL 519
Query: 673 REKAEDQHFE 682
+ + E++ +
Sbjct: 520 KRQEEEERLQ 529
Score = 52.0 bits (123), Expect = 2e-06
Identities = 44/183 (24%), Positives = 92/183 (50%), Gaps = 9/183 (4%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQR--QLEEVEER-QR 559
E + +L + +E++ +R++ + +Q ++++LKR + + +R +LEE E R Q+
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500
Query: 560 ASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDH 619
Q +R E+ R E Q+E + LQ+ + + +L R + E ++L +
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLR---SEQQLRREQEE---RREQLLKREE 554
Query: 620 QSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQ 679
+ RLEQ+ RE+ LK E ++ L + +E + EQ ++L L+ + + +++
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEE 614
Query: 680 HFE 682
E
Sbjct: 615 RRE 617
Score = 51.2 bits (121), Expect = 3e-06
Identities = 52/187 (27%), Positives = 90/187 (48%), Gaps = 21/187 (11%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMK------QLVKQEELKRLYKAQAIQRQLEE--- 553
EEF + L+ +E LRR+ + EK + ++ ++EE K K + + R+ EE
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261
Query: 554 VEERQRASEIQ--GVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMA 611
EE QR E+Q +L K R E Q+E Q Q L + + +R + E
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQR-----LRREQQLRRKQEEERRE 316
Query: 612 QELELEDHQSRLEQ---KLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLE 668
Q+ E + Q R EQ + +++ +E+ ++ E+ L EQE Q+ +R++ + E
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQL--RREQEEERRE 374
Query: 669 EQRIREK 675
+Q RE+
Sbjct: 375 QQLRREQ 381
Score = 51.2 bits (121), Expect = 3e-06
Identities = 47/205 (22%), Positives = 101/205 (49%), Gaps = 25/205 (12%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLY-----KAQAIQRQLEEVEE 556
+ + + Q +L+ ++ LRR+++ E+ +Q ++E+ +R + Q ++R+ EE E
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Query: 557 RQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESEL-----LIMA 611
+Q E + R E+ LR E + +++ QL +E L + + +R E +L L
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQ-QLRREQ---QLRREQQLRREQQLRREQQLRRE 404
Query: 612 QELELEDHQSRLEQKLREKMLKEESQKD-----------EKDLNEEQEVFTELMQVIEQR 660
Q+L E R +Q RE+ L+ E +++ E+ L EQE + ++ E+
Sbjct: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464
Query: 661 DKLVDSLEEQRIREKAEDQHFESFV 685
++ +Q+++ E++ E ++
Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWL 489
Score = 50.8 bits (120), Expect = 4e-06
Identities = 44/168 (26%), Positives = 89/168 (52%), Gaps = 8/168 (4%)
Query: 514 KEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALR 573
++++ R+R++ EK ++ L ++E+L+R +AQ +Q + + ++E Q Q R ++ R
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875
Query: 574 GEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELL-IMAQELELEDHQSRLEQKLREKML 632
+ + + L + K L++ +R E +LL +EL+ E+ + R Q+ +
Sbjct: 876 WQLEEERKRRRHTL--YAKPALQEQ--LRKEQQLLQEEEEELQREEREKRRRQEQERQYR 931
Query: 633 KEE--SQKDEKDLNEEQEVFTELMQVIEQR-DKLVDSLEEQRIREKAE 677
+EE Q++E+ L EE+E + + R DK + EEQ + E+ E
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE 979
Score = 49.7 bits (117), Expect = 9e-06
Identities = 49/202 (24%), Positives = 100/202 (49%), Gaps = 28/202 (13%)
Query: 504 EFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKA----------QAIQRQLEE 553
E +PQL Q +E++ R + + +QL+++ E ++L + Q ++RQ E
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706
Query: 554 VEERQRASEIQGVRLEKALRGEADSGTQDEAQLL--QEWFKLVLEKNKLMRYESELLIMA 611
+ Q +++ LE+ R E + E + L QE ++ +LE+ +L E +
Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766
Query: 612 QELELEDHQSRLEQKLREKMLKEE--SQKDEKDLNEEQEVFTELMQV---IEQRD----- 661
QE D + R E++LR++ +++ SQ+ ++ EE+++ E + +QRD
Sbjct: 1767 QE---RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRW 1823
Query: 662 ---KLVDSLEEQRIREKAEDQH 680
+L +EQR+R++ + Q+
Sbjct: 1824 EEEQLQLEEQEQRLRQERDRQY 1845
Score = 49.3 bits (116), Expect = 1e-05
Identities = 43/187 (22%), Positives = 89/187 (47%), Gaps = 13/187 (6%)
Query: 506 DPQLSLQLKEKKTLRRRKKLEKAMKQLVKQE-------ELKRLYKAQAIQRQLEEVEERQ 558
+P+ + + ++ R ++L++ +QL+++E EL+R Y+ + +Q EE R+
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE 1156
Query: 559 RASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELED 618
+ + LE+ R E + ++E L +E K E+ + R E EL ++ D
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRD 1216
Query: 619 HQSRLEQKLREKMLKEESQKDEKDL--NEEQEVFTEL----MQVIEQRDKLVDSLEEQRI 672
R + K + + KE + +D K E E F +L ++ + + L L EQ+
Sbjct: 1217 EDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 673 REKAEDQ 679
R++ +++
Sbjct: 1277 RDREQER 1283
Score = 49.3 bits (116), Expect = 1e-05
Identities = 52/200 (26%), Positives = 97/200 (48%), Gaps = 31/200 (15%)
Query: 504 EFDPQLSLQLKEKKTLRRRKKL--EKAMKQLVKQEELKRLYKAQAIQRQL-------EEV 554
E + +L Q +E+K L+ ++L ++ +QL + + K + Q + RQ EE
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437
Query: 555 EERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQEL 614
+ R++ E + + E+ LR E ++E QLLQE E+ +L R E + + +E
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE-----REEQQLHRQERDRKFLEEEQ 1492
Query: 615 ELEDHQSRLEQKLRE----------KMLKEE-----SQKDEKDLNEEQEVFTELMQVIEQ 659
+L + ++K RE K L+EE Q+ K L EEQ++ + +
Sbjct: 1493 QLRRQER--DRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550
Query: 660 RDKLVDSLEEQRIREKAEDQ 679
+D+ EE+++R++ E+Q
Sbjct: 1551 QDRDRKFREEEQLRQEREEQ 1570
Score = 48.9 bits (115), Expect = 2e-05
Identities = 46/177 (25%), Positives = 92/177 (51%), Gaps = 10/177 (5%)
Query: 507 PQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASE-IQG 565
P L QL++++ L L++ ++L ++E KR + Q +RQ E E+ Q+ E +
Sbjct: 893 PALQEQLRKEQQL-----LQEEEEELQREEREKR--RRQEQERQYREEEQLQQEEEQLLR 945
Query: 566 VRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQ 625
EK R E + + + +L Q+ +L+ E+ + R + +E EL+ + +L +
Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR 1005
Query: 626 KLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFE 682
+ REK ++E ++ + +E Q+ +L++ E+R+K E++ RE+ E Q E
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLR--EEREKRRLQERERQYREEEELQQEE 1060
Score = 48.9 bits (115), Expect = 2e-05
Identities = 49/206 (23%), Positives = 94/206 (45%), Gaps = 37/206 (17%)
Query: 513 LKEKKTLRRRKKLEKAMKQLVKQEELKR--LYKAQAIQRQLEEVEERQRASEIQGVRLEK 570
L+E++ LRR+++ K +Q ++ +E +R L + Q + RQ + + Q +++ +
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQ 1547
Query: 571 ALRGEADSGTQDEAQLLQEWF-----------KLVLEKNKLMRYESELLIMAQELEL--E 617
R + D ++E QL QE K LE+ K+ R E E M E +L +
Sbjct: 1548 QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607
Query: 618 DHQSRLEQKLREKMLKEES-------------QKDEKDLNE---------EQEVFTELMQ 655
+ Q +L Q+ K ++E ++D K L E EQ++ + +
Sbjct: 1608 EGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDR 1667
Query: 656 VIEQRDKLVDSLEEQRIREKAEDQHF 681
+ ++L+ EEQ++R + D+ F
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKF 1693
Score = 48.5 bits (114), Expect = 2e-05
Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 17/159 (10%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKLEKAMK----------QLVKQEELKRLYKAQAIQRQL 551
+EE + L E++ RRR++LE+ + QL+++E KR + Q +RQ
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR--RRQERERQC 1110
Query: 552 EEVEERQRASE-IQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIM 610
E EE Q+ E + EK R E + ++E ++ QE +L+ E+ + R +
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 611 AQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEV 649
+E EL+ + EQ LRE+ K Q+ E+ EE+E+
Sbjct: 1171 REEEELQQEE---EQLLREEQEKRR-QERERQYREEEEL 1205
Score = 48.1 bits (113), Expect = 3e-05
Identities = 42/175 (24%), Positives = 86/175 (49%), Gaps = 10/175 (5%)
Query: 512 QLKEKKTLRRRKKLEKAMKQLVKQEELKRLY---KAQAIQRQLEEVEERQRASEIQGVRL 568
Q + K+ L+R ++ E+ + L +EE +R + Q ++R+ EE E++ + + RL
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
Query: 569 EKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLR 628
++ LR E + E + Q +L++ + R E E Q L+ E + R + R
Sbjct: 529 QQRLRSEQQLRREQEERREQ-----LLKREEEKRLEQER--REQRLKREQEERRDQLLKR 581
Query: 629 EKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFES 683
E+ +++ K E++ EQ + E ++ +EQ ++ L+ + E+ Q +S
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636
Score = 47.8 bits (112), Expect = 3e-05
Identities = 43/189 (22%), Positives = 90/189 (47%), Gaps = 26/189 (13%)
Query: 512 QLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKA 571
Q + ++ RR++ E+ +QL +++E +R + Q ++R+ EE Q+ Q +R E+
Sbjct: 331 QEERREQQLRREQEERREQQLRREQEEER--REQQLRREQEEERREQQLRREQQLRREQQ 388
Query: 572 LRGEADSGTQDEAQLLQEWFK-LVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREK 630
LR E + + + Q+ + L + + +R E +L +E E E H+ + EQ+ RE+
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL---RREQEEERHEQKHEQERREQ 445
Query: 631 MLKEESQ--------------------KDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQ 670
LK E + K + ++E+E +++ E+ + EQ
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ 505
Query: 671 RIREKAEDQ 679
++R + E++
Sbjct: 506 QLRREQEER 514
Score = 47.0 bits (110), Expect = 6e-05
Identities = 46/182 (25%), Positives = 88/182 (48%), Gaps = 20/182 (10%)
Query: 511 LQLKEKKTLRRRKKLEKAMKQLVKQEELKR--LYKAQAIQRQLEEVEERQRASEIQGVRL 568
LQ +E++ LRR+++ K ++ ++ +E R L + Q ++RQ E + + +++
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 569 EKALRGEADSGTQDEAQLLQEWF---KLVLEKNKLMRYESELLIMAQELELEDHQSRL-- 623
E+ LR + D ++E Q L K E+ ++ R E E + +E +L + R
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
Query: 624 --EQKL--REKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQ 679
EQ L RE+ ++D K L EEQ++ ++RD+ EQ +R + ++
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRR------QERDR---KFREQELRSQEPER 1515
Query: 680 HF 681
F
Sbjct: 1516 KF 1517
Score = 46.2 bits (108), Expect = 1e-04
Identities = 46/169 (27%), Positives = 84/169 (49%), Gaps = 26/169 (15%)
Query: 512 QLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKA 571
+ +++ LRRR+ LE K ++++ +R + + Q + EE E R+R E
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE-EEKEWRKR---------ETV 252
Query: 572 LRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYE-SELLIMAQELELEDHQSRLEQKLREK 630
LR E + ++E Q +E L E+ +L + E EL QE E + + R EQ+LR K
Sbjct: 253 LRKEEEKLQEEEPQRQRE---LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 631 MLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQ 679
+EE ++ +++ E+QE R + + EQ++R + E++
Sbjct: 310 Q-EEERREQQEERREQQE-----------RREQQEERREQQLRREQEER 346
Score = 43.1 bits (100), Expect = 9e-04
Identities = 38/165 (23%), Positives = 80/165 (48%), Gaps = 10/165 (6%)
Query: 508 QLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVR 567
+L + + ++ L+R + E+ +QL+K EE + + Q ++R+ +E E++ E + R
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEE-RRQQQLRREQQERREQRLKREEEEER 667
Query: 568 LEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKL 627
LE+ L+ E + +++ +L E+ + R + I + +LE + K+
Sbjct: 668 LEQRLKREHEEERREQ--------ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKV 719
Query: 628 REKMLKEESQKDEKDLNEE-QEVFTELMQVIEQRDKLVDSLEEQR 671
+ K+E Q+ ++ E+ + +EL E+R EEQR
Sbjct: 720 YSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Score = 41.6 bits (96), Expect = 0.003
Identities = 50/178 (28%), Positives = 84/178 (47%), Gaps = 21/178 (11%)
Query: 515 EKKTLRRRKKLEKAMKQLVKQEE--LKRLYKAQAIQRQLEEVEE--------RQRASEIQ 564
E+K+ R R++L A L +Q E L+ + Q QR L E EE R+R E+Q
Sbjct: 774 EEKSERGRQRLS-ARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ 832
Query: 565 GVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLE 624
+ E+ L+ ++ AQ LQE + E + R + + +LE+ + R
Sbjct: 833 FLEEEEQLQ------RRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRR 886
Query: 625 QKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFE 682
L K +E + E+ L +E+E EL + E+R+K +E++ RE+ + Q E
Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEE--EELQR--EEREKRRRQEQERQYREEEQLQQEE 940
Score = 41.2 bits (95), Expect = 0.003
Identities = 46/196 (23%), Positives = 95/196 (48%), Gaps = 23/196 (11%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELK--RLY---KAQAIQRQLEEVEE 556
+E + +L+ + +E+ R + ++ K QL + + + ++Y + Q QR+ +E EE
Sbjct: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Query: 557 --RQRASEIQGVRLEKALRGEA------DSGTQDEAQLLQEWFKLVLEKNKLMRYESELL 608
R+R SE+Q E+A R + D Q +A+ E + L +R + E
Sbjct: 738 KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE-- 795
Query: 609 IMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQV-----IEQRDKL 663
++L E+ Q R ++ L E+ KE+ ++ ++ +E + E Q+ +Q +
Sbjct: 796 ---RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE 852
Query: 664 VDSLEEQRIREKAEDQ 679
D L+E + R ++++Q
Sbjct: 853 EDGLQEDQERRRSQEQ 868
Score = 40.8 bits (94), Expect = 0.004
Identities = 48/193 (24%), Positives = 92/193 (47%), Gaps = 21/193 (10%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASE 562
EE + + QL+ ++ RR ++L++ ++ ++ LKR ++ + +++L E E+ Q
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER 696
Query: 563 IQGVRLEK---ALRGEAD---SGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELEL 616
I+ R+ K L EAD S + + + ++ K R ESEL QE E
Sbjct: 697 IKS-RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL--QWQEEER 753
Query: 617 EDHQSRLEQKLR----EKMLKEESQKDEKDLN--------EEQEVFTELMQVIEQRDKLV 664
Q + E++ R + +E+S++ + L+ E+++ E Q EQR
Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813
Query: 665 DSLEEQRIREKAE 677
+ +EQR R++ E
Sbjct: 814 EEEKEQRRRQRRE 826
Score = 35.4 bits (80), Expect = 0.18
Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 26/139 (18%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASE 562
E + QL Q ++K + ++ +Q ++ ++ Y+ + Q QLEE E+R R
Sbjct: 1782 EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQER 1841
Query: 563 IQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSR 622
++ R E TQ++++ R E EL QE E + Q R
Sbjct: 1842 ------DRQYRAEEQFATQEKSR----------------REEQELW---QEEEQKRRQER 1876
Query: 623 LEQKLREKMLKEESQKDEK 641
E+KLRE+ ++ + +++++
Sbjct: 1877 -ERKLREEHIRRQQKEEQR 1894
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 60.1 bits (144), Expect = 7e-09
Identities = 122/574 (21%), Positives = 199/574 (34%), Gaps = 93/574 (16%)
Query: 2 SPPKDPSPS-------LPLPSSSSHSSSPPSS---SSTSVSGNAPDGSS---------PP 42
SP + PSP +P P S SP SS S+SG++ SS PP
Sbjct: 316 SPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPP 375
Query: 43 QMTASEPLSQVSRGHPSPPTPNFRRRAVAQGAPREIPLYLPHHPKPEWAEYCL-----VS 97
+ T+S P + R PS P R R P P H P P+ + VS
Sbjct: 376 KRTSSPP-RKTRRLSPSASPPRRRHRPSPPATP---PPKTRHSPTPQQSNRTRKSRVSVS 431
Query: 98 PGEDGLSDPAEMTSDECQPAEAPLGDIGSNHRDPHPIWGKDRSWTGQELSPLAGEDREKG 157
PG ++T + G+ R+ SP K
Sbjct: 432 PGRTS----GKVTKHK-----------GTEKRE----------------SPSPAPKPRKV 460
Query: 158 STGARKEEEGGPVLVKEKLGLKKLVLTQEQKTMLLDWNDSIPESVHLKAGERISQKSAEN 217
+E++GG + + + ++ Q Q++ + S E ER + +N
Sbjct: 461 ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED------ERPKRSHVKN 514
Query: 218 GRGGRVLKPVRPLLLPRAAGEPLPTQRGAQ-----EKMGTPAEQAQGERNVPPPKSPLRL 272
G GR R P + P P +R + + +P+ R P P P R
Sbjct: 515 GEVGR-----RRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRR 569
Query: 273 IANAIRRSLEPLLSNSEGGKKAWAKQESKTLPAQACTRSFSLRKTNSNKDGDQHSPGRNQ 332
RR+ P + S + R +S + P + +
Sbjct: 570 -----RRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR 624
Query: 333 SSAFSPPDPALRTHSLPNRPSKVFPALRSPPCSKIEDVPTLLEKVSLQENFPDASK---- 388
+S PP + P + S RSP S + + + + P +K
Sbjct: 625 ASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684
Query: 389 PPKKRISLFSSLRLKDKSFESFLQESRQR-----KDIRDLFGSPKRKVLPEDSAQALEKL 443
P+ R SS + S + RQ + IR + +P+ K + + ++ + + +
Sbjct: 685 SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSV 744
Query: 444 LQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADE 503
+ S S+ +P P PP PP P + S N+ V +A S T S S
Sbjct: 745 RRVSSSRSV-SGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAK---SPTPSPSPPR 800
Query: 504 EFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEE 537
D + + K+KK ++ KK +K K ++E
Sbjct: 801 NSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKE 834
Score = 40.4 bits (93), Expect = 0.006
Identities = 45/196 (22%), Positives = 75/196 (38%), Gaps = 10/196 (5%)
Query: 375 EKVSLQENFPDASKPPKKRISLFSSLRLKDKSFE-----SFLQESRQRKDIRDLFGSPKR 429
EK S +E + S+ P++R S S R + S + R R R +P++
Sbjct: 158 EKESSREK-RERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEK 216
Query: 430 KV----LPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQ 485
K LPE S + E +Q STS P P P P P P P K
Sbjct: 217 KEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRP 276
Query: 486 VTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQ 545
+ + S + S + S + P+ + + + RR+ + ++ +R+
Sbjct: 277 RSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPP 336
Query: 546 AIQRQLEEVEERQRAS 561
+R V R+R+S
Sbjct: 337 RHRRSRSPVRRRRRSS 352
Score = 40.4 bits (93), Expect = 0.006
Identities = 54/211 (25%), Positives = 84/211 (39%), Gaps = 17/211 (8%)
Query: 297 KQESKTLPAQACTRSFSLRKTNS-----NKDGDQHSPG-RNQSSAFSP-PDPALRTHSLP 349
K+E P + +RS S R+ +S K SP R +S + SP P+ +T LP
Sbjct: 165 KRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELP 224
Query: 350 NRPSKVFPALRSPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFES 409
KV + P + +L KV E P+ +P ++ +S + K+K
Sbjct: 225 EPSVKV----KEPSVQEATSTSDIL-KVPKPEPIPEPKEPSPEK----NSKKEKEKEKTR 275
Query: 410 FLQESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPP 469
SR + R SP P ++ + P + S R+ P PP PP
Sbjct: 276 PRSRSRSKSRSRTRSRSPSH-TRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP 334
Query: 470 PTAGGADSKNFPLRAQVTEASSSASSTSSSS 500
P R + + + S +SS+SSSS
Sbjct: 335 PPRHRRSRSPVRRRRRSSASLSGSSSSSSSS 365
Score = 30.8 bits (68), Expect = 4.4
Identities = 33/160 (20%), Positives = 68/160 (42%), Gaps = 17/160 (10%)
Query: 497 SSSSADEEFD---PQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQL-- 551
+S+ D F +L QLK + L ++ + K +++K KR+ + + +
Sbjct: 9 TSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVI 68
Query: 552 ----EEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESEL 607
++E + S++ + L L G+ E W L+ + + S
Sbjct: 69 EFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGEL-----WPLLLSAQENIAGIPSAF 123
Query: 608 LIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQ 647
L + +E E Q ++EQ+ M K++ KD++D E++
Sbjct: 124 LELKKE---EIKQRQIEQEKLASMKKQDEDKDKRDKEEKE 160
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 59.7 bits (143), Expect = 9e-09
Identities = 88/415 (21%), Positives = 149/415 (35%), Gaps = 74/415 (17%)
Query: 233 PRAAGEPLPTQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGK 292
P A G P P +R + E+ ER KS L A RSL+ S +
Sbjct: 394 PNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSAL-----ARERSLKKRQSLPASPR 448
Query: 293 KAWAKQESKTLPAQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRP 352
+ + L ++ R S + SPG + PP P T S R
Sbjct: 449 ARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRV 508
Query: 353 SKVFPALRSPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQ 412
+ A SP + ED + S N +++ P
Sbjct: 509 RRKEEAKESPSAAGPEDKSQSKRRAS---NEKESAAP----------------------- 542
Query: 413 ESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPP-PPPPPT 471
SP P + +K P ++ + PP P PP P P
Sbjct: 543 ------------ASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPM 590
Query: 472 AGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQ 531
AG D R + T + + + E + + LQ + K +R +Q
Sbjct: 591 AGTTD------REEATRLLAEKRRQAREQRERE-EQERRLQAERDKRMRE--------EQ 635
Query: 532 LVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWF 591
L ++ E + +A+A +R+ +E E+ +A + + RL+K + EA++ +++EA+
Sbjct: 636 LAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQ-KEEAEARSREEAE------ 688
Query: 592 KLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEE 646
R E E QE E ++ + RLE+ ++ E S+ +K ++E
Sbjct: 689 --------RQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKE 735
Score = 48.9 bits (115), Expect = 2e-05
Identities = 162/754 (21%), Positives = 251/754 (33%), Gaps = 132/754 (17%)
Query: 8 SPSLPLPSSSSHSSSPPSSSSTSVSGNAPDGSSPPQMTASEPLSQVSRGHPSPPTPNFRR 67
+P P PS S PP S V PD +PP M + Q+ SP
Sbjct: 21 TPPEPRPSPEGDPSPPPPPMSALVPDTPPD--TPPAMKNATSSKQLPLEPESPS------ 72
Query: 68 RAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLS---DPAEMTSDECQPAEAPLGDI 124
Q PR P P+ E SP + S P M + +P
Sbjct: 73 ---GQVGPRPAP------PQEE-------SPSSEAKSRGPTPPAMGPRDARPPRR----- 111
Query: 125 GSNHRDPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLVKEKLGLKKLVLT 184
S+ P + D T QE+ AGE + R+EE + K+ + L+K
Sbjct: 112 -SSQPSPTAVPASDSPPTKQEVKK-AGERHKLAKE--RREERAKYLAAKKAVWLEKEEKA 167
Query: 185 QEQKTMLLDWNDSIPESVHLKAGERISQKSAENGRGGRVLKPVRPLLLPRAAGEPLPTQR 244
+ + L E LKA +R + + K + R+ + R
Sbjct: 168 KALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIR 227
Query: 245 GAQEKMG------TPAEQAQGER----NVPPPKSPLRLIANAIRRSLEPLLSNSEGGKK- 293
+ +P + G R V PK +I + +S L ++ +
Sbjct: 228 QQRWSWAGALHHSSPGHKTSGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSL 287
Query: 294 ---AWAKQ-----ESKTLPAQACTRSFSLRKTNSNKDGDQHSPGRNQS------SAFSPP 339
AW + TL A +RS N G PGR + S P
Sbjct: 288 QLSAWESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQGRGCDPGRGPTWGRAGASLARGP 347
Query: 340 DPALRTHSLPNRPSKVFPALRSP--PCSKIEDVPTLL---EKVSLQENFPDASKPPKKRI 394
P RTH P A SP PCS V E+ ++ S P +R
Sbjct: 348 QPD-RTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERGERRKPNAGGSPAPVRRR 406
Query: 395 SLFSSLRLKDKSFE--------SFLQESRQRKDIRDLFGSPKRKVLPEDSAQAL--EKLL 444
S ++ K+K + S L R K + L SP+ ++ +++ K
Sbjct: 407 PEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKAR 466
Query: 445 QPFKSTSLRQAAPPPPPP------PPPPPPP--------------------PTAGGADSK 478
STS + A P P P PP PP P P+A G + K
Sbjct: 467 PSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDK 526
Query: 479 NFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKL------------- 525
+ R E S+A ++ + S P + KE+
Sbjct: 527 SQSKRRASNEKESAAPASPAPSPAPS--PTPAPPQKEQPPAETPTDAAVLTSPPAPAPPV 584
Query: 526 --EKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDE 583
K M +EE RL + +RQ E ER+ E+ L+ E D ++E
Sbjct: 585 TPSKPMAGTTDREEATRLLAEK--RRQAREQREREEQ--------ERRLQAERDKRMREE 634
Query: 584 AQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDL 643
+ + E R E E AQ + E Q RL+++ E + + + + L
Sbjct: 635 QLAREAEARAEREAEARRREEQEAREKAQAEQEE--QERLQKQKEEAEARSREEAERQRL 692
Query: 644 NEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAE 677
E+ + + E+R +L + ++ R E +E
Sbjct: 693 EREKHFQQQEQERQERRKRLEEIMKRTRKSEVSE 726
>gi|171906567 peripheral benzodiazepine receptor-associated protein
1 isoform b [Homo sapiens]
Length = 1797
Score = 57.8 bits (138), Expect = 3e-08
Identities = 113/466 (24%), Positives = 192/466 (41%), Gaps = 34/466 (7%)
Query: 239 PLPTQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQ 298
P P GA E P + P S IA+ +L+ SE K
Sbjct: 8 PRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEESSKPKGDG 67
Query: 299 ESKTLP------AQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRP 352
S+ + A+AC S + ++S + P + AF A S +RP
Sbjct: 68 SSRPVGGTDPEGAEACLPSLGQQASSSGPACQR--PEDEEVEAFLK---AKLNMSFGDRP 122
Query: 353 S----KVFPALRSPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISL-FSSLRLKDKSF 407
+ + LR C+ +++ +L K S E + +K L + RL++++
Sbjct: 123 NLELLRALGELRQR-CAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERAR 181
Query: 408 ESFLQESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPP 467
+ LQE+ R + L +S + + +L + + R+ P PP PP P
Sbjct: 182 K--LQETNLRVEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPA 239
Query: 468 PPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEK 527
AG A + P A E + + E+ QL +L +K+ + E
Sbjct: 240 LQARAG-APAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEA 298
Query: 528 AMKQLVKQEELKRLYKAQAIQRQLEEVEERQ--RASEIQGVRLEKA-LRGEADSGTQDEA 584
KQ +E +L +AQ +L E R RA+E + V E A LRG+ TQ+
Sbjct: 299 RKKQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERD 358
Query: 585 QLLQ--EWFKLVLEK-NKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEK 641
L+ + + LE +++++ E+ Q+LE+E Q+RL LREK +EE ++ ++
Sbjct: 359 SALRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARL--SLREK--QEEVRRLQQ 414
Query: 642 DLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESFVFS 687
E Q +Q++E +DS+ + R+RE E ++ FS
Sbjct: 415 AQAEAQREHEGAVQLLE---STLDSM-QARVRELEEQCRSQTEQFS 456
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 57.0 bits (136), Expect = 6e-08
Identities = 50/189 (26%), Positives = 97/189 (51%), Gaps = 22/189 (11%)
Query: 507 PQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGV 566
PQ+ +++ R+ ++L + K++ KQEE K + +L E E + R E +
Sbjct: 225 PQVQTNTLQEEMWRQEEELREQEKKIRKQEE-----KMWRQEERLREQEGKMREQEEKMR 279
Query: 567 RLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQEL-ELEDHQSRLEQ 625
R EK LR E + +++ + L+E KL ++ ++ E ++ +++ E E+ R E+
Sbjct: 280 RQEKRLR-EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
Query: 626 KL--REKMLKEESQK----------DEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIR 673
+L +EK ++E+ QK ++ L E++E E ++ EQ +K+ EE+RIR
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKM---QEEERIR 395
Query: 674 EKAEDQHFE 682
E+ + E
Sbjct: 396 EREKKMREE 404
Score = 57.0 bits (136), Expect = 6e-08
Identities = 49/186 (26%), Positives = 97/186 (52%), Gaps = 21/186 (11%)
Query: 514 KEKKTLRRRKKLEKAMKQLVKQE-ELKRLYKAQAIQRQLEEVEERQRASE---------- 562
+E+K R+ K+L + K+L +QE EL+ K + + Q++E EE+ E
Sbjct: 274 QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM 333
Query: 563 -IQGVRL---EKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELED 618
Q RL EK +R E + +D+ + + E + + EK + MR + ++ ++++ E+
Sbjct: 334 WRQEERLWEQEKQMR-EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEE 392
Query: 619 HQSRLEQKLRE-----KMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIR 673
E+K+RE + +E+ QK E+++ E++E + ++ EQ++KL + + Q
Sbjct: 393 RIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE 452
Query: 674 EKAEDQ 679
EK +Q
Sbjct: 453 EKIWEQ 458
Score = 55.8 bits (133), Expect = 1e-07
Identities = 46/186 (24%), Positives = 102/186 (54%), Gaps = 16/186 (8%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLY--KAQAIQRQLEEVEERQR 559
+E + + L+ +EKK ++ +K+ + ++L +QE R K + +++L E E+ R
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR 293
Query: 560 ASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMR-----YESELLIMAQEL 614
E + +R +K LR + + + E ++ ++ K+ ++ K+ R +E E + QE
Sbjct: 294 EQE-KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 352
Query: 615 ELEDHQSRL---EQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQR 671
++ D + R+ +++LRE KEE ++++ + E++E E ++ E+ K+ + EE+
Sbjct: 353 KMRDQEERMWEQDERLRE---KEERMREQEKMWEQEEKMQEEERIREREKKMRE--EEET 407
Query: 672 IREKAE 677
+RE+ E
Sbjct: 408 MREQEE 413
Score = 53.1 bits (126), Expect = 8e-07
Identities = 36/179 (20%), Positives = 95/179 (53%), Gaps = 6/179 (3%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRAS 561
+E Q + +E+K +K E+ K ++E+++ + + ++++ E EE R
Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
Query: 562 EIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQS 621
E + E+ +R + + + E ++ ++ K+ ++ K+ E E + QE + + +
Sbjct: 580 EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE 639
Query: 622 RLEQKLREKMLKEES---QKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAE 677
+++++ EKM ++E +++EK +E+++ + ++ EQ +K+ +E+++RE+ E
Sbjct: 640 KMQEQ-EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG--QEEKMREQEE 695
Score = 52.8 bits (125), Expect = 1e-06
Identities = 49/188 (26%), Positives = 94/188 (50%), Gaps = 25/188 (13%)
Query: 515 EKKTLRRRKKL-----EKAMKQLVKQEELKRLYKAQAI--QRQLEEVEERQRASEIQGVR 567
+KK ++KL EK+ QL +E ++L +A+ + Q Q ++E E +
Sbjct: 186 KKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245
Query: 568 LEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKL 627
EK +R + + + E +L ++ K+ ++ K+ R E L +EL ++ + R ++KL
Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKL 305
Query: 628 R----------EKMLKEES---QKDEKDLNEEQEVFTELMQVIEQRDKLVDSLE-----E 669
R EKM ++E +++EK +E+ ++ + Q+ EQ K+ D E +
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365
Query: 670 QRIREKAE 677
+R+REK E
Sbjct: 366 ERLREKEE 373
Score = 50.8 bits (120), Expect = 4e-06
Identities = 40/174 (22%), Positives = 98/174 (56%), Gaps = 13/174 (7%)
Query: 514 KEKKTLRRRKKLEKAMKQLVKQEE-LKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKAL 572
++ + LR +++ + K++ +QEE ++ K Q +++ + EE+ R E R EK +
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRER-EKKM 569
Query: 573 RGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRL-EQKLREKM 631
R E + + E ++ ++ K+ ++ K+ +E E + QE ++ + + ++ EQ+ +KM
Sbjct: 570 REEEEMMREQEEKMQEQEEKMREQEEKM--WEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
Query: 632 LKEES---QKDEKDLNEEQEVFTELMQVIEQRDKLVDSLE-----EQRIREKAE 677
++E +++EK +E++++ + ++ EQ +K+ + E E+++RE+ E
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Score = 50.1 bits (118), Expect = 7e-06
Identities = 38/183 (20%), Positives = 101/183 (55%), Gaps = 18/183 (9%)
Query: 512 QLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRL--- 568
+++E++ +R R+K + +++++++E K + + ++ Q E++ E++ + Q ++
Sbjct: 555 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 614
Query: 569 -EKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRL---E 624
EK E + Q++ +++ E + + E+ + M +E E + QE ++ + + ++ E
Sbjct: 615 EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM-WEQEEKMREQEEKMREQEEKMQGQE 673
Query: 625 QKLREKMLKEESQKD------EKDLNEEQEVFTELMQVIEQRDKLVDSLE----EQRIRE 674
+K+RE+ K + Q++ EK +E++++ + ++ Q +K+ E E+RIR+
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD 733
Query: 675 KAE 677
+ E
Sbjct: 734 QKE 736
Score = 48.1 bits (113), Expect = 3e-05
Identities = 37/182 (20%), Positives = 92/182 (50%), Gaps = 17/182 (9%)
Query: 512 QLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKA 571
+++E++ +R R+K + ++ ++++E K + + + Q E+ ++QR E + E+
Sbjct: 387 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446
Query: 572 LRGEADSGTQDEAQLLQEWFKLVLEKNKLMR-----------YESELLIMAQELELEDHQ 620
E + ++ + +++ ++ ++ K+ R +E E + QE ++ D +
Sbjct: 447 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
Query: 621 SRL---EQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAE 677
R+ +++LRE KEE +++K + +++E E + EQ K D E+ R E+
Sbjct: 507 ERMWEQDERLRE---KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 678 DQ 679
++
Sbjct: 564 ER 565
Score = 47.4 bits (111), Expect = 5e-05
Identities = 41/184 (22%), Positives = 93/184 (50%), Gaps = 5/184 (2%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASE 562
EE + Q ++K+ L ++K+++ +++ +QEE R + Q + +E+ R E
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485
Query: 563 IQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSR 622
Q E+ +R + + D+ + + E + + EK + MR + ++ +++ E
Sbjct: 486 DQMWEQEEKMRDQ-EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQE 544
Query: 623 LEQKL---REKMLKEESQKD-EKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAED 678
E+K EKM +EE ++ EK + EE+E+ E + ++++++ + EE+ ++ +
Sbjct: 545 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM 604
Query: 679 QHFE 682
Q E
Sbjct: 605 QEQE 608
Score = 46.6 bits (109), Expect = 8e-05
Identities = 38/188 (20%), Positives = 95/188 (50%), Gaps = 12/188 (6%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASE 562
E+ Q +Q +E+K + +K+ + +++++ R K + + Q+ E EE+ R E
Sbjct: 440 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
Query: 563 IQGVRLEKALRGEADSGTQDEAQLLQEWFKL------VLEKNKLMRYESELLIMAQELEL 616
Q + ++ E D +++ + ++E K+ + E+ K E + +++
Sbjct: 500 -QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE 558
Query: 617 EDHQSRLEQKLREK--MLKEESQK---DEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQR 671
E+ E+K+RE+ M++E+ +K E+ + E++E E + ++++++ + EE+
Sbjct: 559 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 618
Query: 672 IREKAEDQ 679
++ ED+
Sbjct: 619 WEQEEEDK 626
Score = 46.6 bits (109), Expect = 8e-05
Identities = 44/177 (24%), Positives = 91/177 (51%), Gaps = 29/177 (16%)
Query: 515 EKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQ---------LEEVEERQRAS---- 561
++K + R++K+ + Q+ +QEE R + + ++ L E EER R
Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530
Query: 562 -EIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQ 620
+ + +R EK + E + T D+ + ++E ++ E+ K MR E E++ E E+
Sbjct: 531 QQEEKMREEKKTQ-EQEKKTWDQEEKMREEERM-REREKKMREEEEMM-----REQEEKM 583
Query: 621 SRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAE 677
E+K+RE+ +E+ + E+ + E++E ++ EQ +K+ + EE +++E+ E
Sbjct: 584 QEQEEKMREQ--EEKMWEQEEKMQEQEE------KMWEQEEKMWEQEEEDKMQEQEE 632
Score = 45.4 bits (106), Expect = 2e-04
Identities = 44/188 (23%), Positives = 96/188 (51%), Gaps = 21/188 (11%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQR--QLEEVEERQR 559
++ ++ + ++ +E+K R+ ++L + KQ+ +QE+ R + + ++ +L E EER R
Sbjct: 317 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 376
Query: 560 ASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELL-----IMAQEL 614
E + EK E + ++E K + E+ + MR + E + M ++
Sbjct: 377 EQEKMWEQEEK----------MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426
Query: 615 ELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIRE 674
E E Q RL ++ + +E+ Q+ E+ + E++E + ++ Q K+ ++++RE
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM---WRQEKMRE 483
Query: 675 KAEDQHFE 682
+ EDQ +E
Sbjct: 484 Q-EDQMWE 490
Score = 39.7 bits (91), Expect = 0.010
Identities = 36/169 (21%), Positives = 88/169 (52%), Gaps = 9/169 (5%)
Query: 511 LQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEK 570
+Q +E+K + +K+ + +++ +QEE ++++ + + EE ++ Q E+ + EK
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEE--KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEK 640
Query: 571 ALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSR-LEQKLR- 628
E Q+E QE K+ ++ K+ E ++ ++++ ++ + R E+K+R
Sbjct: 641 MQEQEEKMWEQEEKMREQE-EKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRG 699
Query: 629 --EKMLKEESQK--DEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIR 673
EKM +E + E+ + ++E+ + ++ +Q++K+ + L E R
Sbjct: 700 QEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
Score = 38.1 bits (87), Expect = 0.028
Identities = 27/157 (17%), Positives = 84/157 (53%), Gaps = 6/157 (3%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLY----KAQAIQRQLEEVEER 557
++ ++ + +Q +E+K + +K+ + ++ QE+ + ++ K Q + ++ E EE+
Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Query: 558 QRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELE 617
R E + E+ ++G+ + + E ++ + K+ ++ K+ E ++ +++ +
Sbjct: 655 MREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQ 714
Query: 618 DHQSRLEQKLREK--MLKEESQKDEKDLNEEQEVFTE 652
+ + ++++REK ++++ +K ++ L E +E +E
Sbjct: 715 EEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSE 751
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 57.0 bits (136), Expect = 6e-08
Identities = 52/198 (26%), Positives = 80/198 (40%), Gaps = 27/198 (13%)
Query: 290 GGKKAWAKQESKTLPAQACTRSFSL---RKTNSNKDGDQHSPGRNQSSAFSPPDPALRTH 346
G ++ A S+ P AC + + L R+ + D HS + S P+P R
Sbjct: 132 GAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSS-----PEPWARPS 186
Query: 347 SLPNRPSKVFPALR-SPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFS------- 398
P P R SPP S ++ P L +++L P PP ++ +
Sbjct: 187 CTPQEGGCPRPKERESPPPSALQ--PVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPP 244
Query: 399 -------SLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTS 451
+L D S + + IR+L G+ ++ + ++AL LL T
Sbjct: 245 PPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAK--LSEALSALLPLLPGTP 302
Query: 452 LRQAAPPPPPPPPPPPPP 469
+ PP PPPPPPPPPP
Sbjct: 303 VDSLPPPLPPPPPPPPPP 320
Score = 45.1 bits (105), Expect = 2e-04
Identities = 21/40 (52%), Positives = 24/40 (60%)
Query: 452 LRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASS 491
L Q AP PP PPPPP PPPT +D LRAQ A++
Sbjct: 233 LAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANA 272
Score = 41.6 bits (96), Expect = 0.003
Identities = 34/105 (32%), Positives = 44/105 (41%), Gaps = 19/105 (18%)
Query: 427 PKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQV 486
PK + P SA LQP + L A PPPP PP PPPPP A A S P
Sbjct: 197 PKERESPPPSA------LQPVQLPRL--ALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPR 248
Query: 487 TEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQ 531
+ SAS DP L +++T ++L ++Q
Sbjct: 249 PPPTLSAS-----------DPSLDFLRAQQETANAIRELAGTLRQ 282
>gi|24308354 hypothetical protein LOC89927 isoform 1 [Homo sapiens]
Length = 204
Score = 57.0 bits (136), Expect = 6e-08
Identities = 38/141 (26%), Positives = 72/141 (51%), Gaps = 5/141 (3%)
Query: 550 QLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNK-----LMRYE 604
+ E+ R A E + E+ R + D + E ++ E +L + K + L+R E
Sbjct: 12 EAEKPLRRYGAVEETAWKTERLGRNQLDIISMAETTMMPEEIELEMAKIQRLREVLVRRE 71
Query: 605 SELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLV 664
SEL M +++L L+Q+L+ + E +K + E E+ ++ +++++RD LV
Sbjct: 72 SELRFMMDDIQLCKDIMDLKQELQNLVAIPEKEKTKLQKQREDELIQKIHKLVQKRDFLV 131
Query: 665 DSLEEQRIREKAEDQHFESFV 685
D E +R+RE+ ED+ F+
Sbjct: 132 DDAEVERLREQEEDKEMADFL 152
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 56.6 bits (135), Expect = 8e-08
Identities = 126/529 (23%), Positives = 196/529 (37%), Gaps = 103/529 (19%)
Query: 234 RAAGEPLP-----------TQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLE 282
R +G+P P TQ G+ E P + + +P RL+ N
Sbjct: 1117 RGSGKPRPKSEGFELYNNSTQNGSPESPQLPWAEYSEPKKLPGDD---RLMKNRADHRSS 1173
Query: 283 PLLSN---SEGGKKAWA------------------------KQESKTLPAQACTRSFSLR 315
P ++N S GGK A+A + E+ +P Q TR +
Sbjct: 1174 PNVANQPPSPGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTF 1233
Query: 316 KTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRPSKVFPALRSPPCSKIEDVPTLLE 375
++K D+ +P +NQ + P + T S N S + ED LE
Sbjct: 1234 P--ASKSQDRMAPPQNQWPNYEEK-PHMHTDS--NHSSIAIQRVTRSQEELREDKAYQLE 1288
Query: 376 KVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFGS-PKRKVLPE 434
+ ++ D I+ SSL S E S+ L S P R P
Sbjct: 1289 RHRIEAAM-DRKSDSDMWINQSSSLDSSTSSQEHLNHSSKSVTPASTLTKSGPGRWKTPA 1347
Query: 435 DSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGAD--SKNFPL-------RAQ 485
+ QP ++ PPPPPPPP AG D S + PL +
Sbjct: 1348 AIPATPVAVSQPIRTDL---------PPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIG 1398
Query: 486 VTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQE--------- 536
+ A +A+ + + + +L+E++ R+R++ E+ + Q+ Q
Sbjct: 1399 LPSAQVAAAERRKREEHQRWYEKEKARLEEERE-RKRREQERKLGQMRTQSLNPAPFSPL 1457
Query: 537 --ELKRLYKAQAIQRQLEEV------EERQRASEIQGVRLEKALRGEADSGTQDEAQLLQ 588
+ + K +QR E V +++ R E + ++ + E SG +
Sbjct: 1458 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1517
Query: 589 EWFKLVLEKNKLMRYESELLIMAQELELE-DHQSRLEQKLR--------EKMLKEESQKD 639
K LEK + M L QEL+ + D + +LR +K L+E QKD
Sbjct: 1518 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1577
Query: 640 EKDLNEE-QEVFTEL-MQVIEQRDKLVD-------SLEEQRIREKAEDQ 679
E D EE +V T L MQ +E + D LEE R RE AED+
Sbjct: 1578 EDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKRE-AEDR 1625
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 56.6 bits (135), Expect = 8e-08
Identities = 129/598 (21%), Positives = 215/598 (35%), Gaps = 74/598 (12%)
Query: 3 PPKDPSPSLPLPSSSSHSSSPPSSS--STSVSGNAPDGSSPPQMTASEPLSQVSRGHP-S 59
PP+ P P+ P P S+ PPS S S P + P +++P+SQ G P
Sbjct: 510 PPQQPGPAKPSPQQPG-STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ 568
Query: 60 PPTPN-FRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLSDPAEMTSDECQPAE 118
PPT + ++ +QG P+ I P E L P + + T ECQ
Sbjct: 569 PPTVSPSAKQPPSQGLPKTI------CPLCNTTELLLHVPEKANFN-----TCTECQTTV 617
Query: 119 APLGDIGSNHRDPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLVKEKLGL 178
L N PH K+ ++ G D + + + + PV +
Sbjct: 618 CSLCGFNPN---PHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSK 674
Query: 179 KKLVLTQEQKTMLLDWNDSIPESVHLKAGE------RISQKSAENGRGGRVLKPVRPLLL 232
Q Q+T D+ P+ KA E + Q + + +P L
Sbjct: 675 SS---PQPQQTS--PKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSL 729
Query: 233 PRAAGEPLPTQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGK 292
+ A P+ Q+K A A + P P + ++ + +P + +S
Sbjct: 730 SKPAPPKEPSVPSEQDK----APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS---- 781
Query: 293 KAWAKQESKTLPAQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSP---PDPA----LRT 345
K ++ E KT P KT+S K P + S F P PA + +
Sbjct: 782 KVQSQAEEKTTPP---------LKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS 832
Query: 346 HSLPNRPSKVFPALRSPPCSKIEDVPTLLEKVSLQENFPDAS-------KPPKKRISLFS 398
H P+ SK + P K E+ K+S + PDA PP R +
Sbjct: 833 HPGPSSESK--GQKQVDPVQKKEEPKKAQTKMSPK---PDAKPMPKGSPTPPGPRPTAGQ 887
Query: 399 SLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPP 458
++ +S + Q R ++ + +PK + P + + L F ++ QA+
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQ--PTTPQETVTGKLFGFGASIFSQASNL 945
Query: 459 PPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKT 518
P P + GA K P +Q + ST + P S+ +K++
Sbjct: 946 ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPP----APAKSIPVKKETK 1001
Query: 519 LRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEA 576
+KLE +Q + + K I+ E Q+A + +LEK+ + E+
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKA--VLPTKLEKSPKPES 1057
Score = 49.7 bits (117), Expect = 9e-06
Identities = 36/95 (37%), Positives = 45/95 (47%), Gaps = 9/95 (9%)
Query: 376 KVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVLPED 435
K SL E D PP I+L +L F S +++ + GSP LP
Sbjct: 2332 KSSLSETVFD--HPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPA- 2388
Query: 436 SAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPP 470
K F+S+SL +A PPPPPPPPPPPPP
Sbjct: 2389 ------KPRPFFRSSSLDISAQPPPPPPPPPPPPP 2417
Score = 42.4 bits (98), Expect = 0.001
Identities = 150/732 (20%), Positives = 258/732 (35%), Gaps = 130/732 (17%)
Query: 4 PKDPSPSL---PLPSSSSHSSSPPSSSSTSVSGNAP---DGSSPPQMTASEPLSQVSRGH 57
P P P L P+ ++S+ S S P TS +A D S P+ PL + H
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 58 PSPPTPNFRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLSDPAEMTSDECQPA 117
SP A A+ P L P PK P D A + D+ +
Sbjct: 714 GSPS-------AKAKQPPEADSLSKPAPPK---------EPSVPSEQDKAPVADDKPKQP 757
Query: 118 EA--PLGDIGSNHR---DPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLV 172
+ P D+ S+ P K +S ++ +P D K S + P
Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS------QSFPPTGE 811
Query: 173 KEKLGLKKLVLTQEQKTMLLDWNDSIPESVHLKAGERISQKSAENGRGGRVLKPVRPLLL 232
K K + + ++ ES K + + QK E + + P +P
Sbjct: 812 KVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV-QKKEEPKKAQTKMSP-KPDAK 869
Query: 233 PRAAGEPLPTQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGK 292
P G P P P + + VP P+ + + R SL L +
Sbjct: 870 PMPKGSPTP-----------PGPRPTAGQTVPTPQQSPKPQEQSRRFSLN--LGSITDAP 916
Query: 293 KAWAKQESKTLPAQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRP 352
K+ +T+ + S+ SN PG + S P ++ P++P
Sbjct: 917 KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG---PGAPMKQAPAPSQP 973
Query: 353 SKVFPALRSPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQ 412
P + PP S + P P S P KK ++ +L+ K+ ++
Sbjct: 974 ----PTSQGPPKSTGQAPPA-----------PAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
Query: 413 ESRQR-------KDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPP 465
+ + KD + L P++ VLP LEK +P + L + PP
Sbjct: 1019 KRTETEKKPPPIKDSKSLTAEPQKAVLPTK----LEKSPKPESTCPLCKTELNIGSKDPP 1074
Query: 466 -------------------PPPPPTA---------------GG--ADSKNFPLRAQVTEA 489
P P T G D + P +A
Sbjct: 1075 NFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKA 1134
Query: 490 SSSASSTSSSSADEEFDPQLSLQLKEKKTLR--RRKKLEKAMKQLVKQEELKRLYKAQAI 547
S T SSS PQ+ L K+++ ++ K + + +K+ + E++ +
Sbjct: 1135 SPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTD-- 1192
Query: 548 QRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESEL 607
Q+Q E E+ +AS +Q EK E +E ++ E K +LE+ K + +L
Sbjct: 1193 QKQEESKLEKDKASALQ----EKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKL 1248
Query: 608 LIMAQELELEDHQSRL--------EQKLREKMLKEESQKDEKDLNEEQEVFTELMQVI-E 658
L A+ E+ + L E+KL ++ + Q+ ++ + + + + Q + +
Sbjct: 1249 LPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPK 1308
Query: 659 QRDKLVDSLEEQ 670
+ DK +++EQ
Sbjct: 1309 EDDKTTKTIKEQ 1320
Score = 40.0 bits (92), Expect = 0.007
Identities = 64/284 (22%), Positives = 100/284 (35%), Gaps = 24/284 (8%)
Query: 196 DSIPESVHLKAGERISQKSAENGRGGRVLKPVR-PLLLPRAAGEPLPTQRGAQEKMGTPA 254
D P+S+ + E+I KS G G KP++ P P+ LP QR A A
Sbjct: 233 DGTPKSISSQQPEKI--KSQPPGTG----KPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
Query: 255 EQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAW--AKQESKTLPAQACTRSF 312
+ +GE P SP S P+ + G A ++S+ PA+ +
Sbjct: 287 DIVRGESVKPSLPSP----------SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPS 336
Query: 313 SLRKTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRPSKVFPALRSPPCSKIEDVPT 372
L K + + G P + + P P + P+ P + P
Sbjct: 337 GLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG 396
Query: 373 LLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVL 432
+ + + Q P +KPP +++ L + +S + K G K
Sbjct: 397 VGKTPAQQ---PGPAKPPTQQVGTPKPLA-QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452
Query: 433 PEDSAQALEKLLQPFKSTS-LRQAAPPPPPPPPPPPPPPTAGGA 475
+ + P K S L A PPP P P PPP G+
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS 496
Score = 38.9 bits (89), Expect = 0.016
Identities = 135/663 (20%), Positives = 231/663 (34%), Gaps = 117/663 (17%)
Query: 2 SPPKDPSPSLPLPSSSSHSSSPPSSSSTSVSGNAPDGSSPPQMTASEPLSQVSRGHPSPP 61
SP KD +P L + PP ++ G+ P A +P S P+PP
Sbjct: 683 SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS-------PSAKAKQPPEADSLSKPAPP 735
Query: 62 ----TPNFRRRA-VAQGAPREIPLYLPHHP---------KPEWAEYCLVSPGEDGLSDPA 107
P+ + +A VA P++ + P KP+ + S E+ + P
Sbjct: 736 KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Query: 108 EMTSDECQPAEAPLGDIGS---NHRDPHPIW--------GKDRSWTGQ-ELSPLAGEDRE 155
+ S + + P G+ S + P P G GQ ++ P+ ++
Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP 855
Query: 156 KGST-------GARKEEEGGPVLVKEKLGLKKLVLTQEQK----------TMLLDWNDSI 198
K + A+ +G P + + V T +Q ++ L
Sbjct: 856 KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA 915
Query: 199 PESVHLKAGERISQKSAENGRGGRVLKPVRPLLLPRAAGEPLPTQRGAQEKMGTPAEQAQ 258
P+S E ++ K G G + L+ AG+P P +Q G P +QA
Sbjct: 916 PKSQPTTPQETVTGKLF--GFGASIFSQASNLI--STAGQPGPH---SQSGPGAPMKQAP 968
Query: 259 GERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQESKTLPAQACTRSFSLRKTN 318
P + P + A +K++P + T++ + K
Sbjct: 969 APSQPPTSQGPPKSTGQA-------------------PPAPAKSIPVKKETKAPAAEKLE 1009
Query: 319 SNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRPSKVFPALRSPPCSKIEDVPTLLEKVS 378
+ +P ++ P P + SL P K +PT LEK
Sbjct: 1010 PKAE---QAPTVKRTETEKKPPPIKDSKSLTAEPQKAV-------------LPTKLEKSP 1053
Query: 379 LQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFG-SPKRKVLPEDSA 437
P+++ P K + L + K +F + + + +L G +P +
Sbjct: 1054 K----PESTCPLCK-----TELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 438 QALEKLLQPFKSTSL---RQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSAS 494
L Q S L R+ P P P P P PT + P + ++ +
Sbjct: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
Query: 495 STSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELK-RLYKAQAIQRQLEE 553
T + E K K+TL +K+ + KQEE K KA A+Q +
Sbjct: 1165 KTEAEKVILE---------KVKETL-SMEKIPPMVTTDQKQEESKLEKDKASALQEKKPL 1214
Query: 554 VEERQRASEIQGVRL-EKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQ 612
EE++ E + +R EK E T ++ +LL E E+ K +S++ I +
Sbjct: 1215 PEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEE 1274
Query: 613 ELE 615
+LE
Sbjct: 1275 KLE 1277
Score = 37.0 bits (84), Expect = 0.062
Identities = 135/592 (22%), Positives = 228/592 (38%), Gaps = 112/592 (18%)
Query: 137 KDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLVKEKLGLKKLVLTQEQKTMLLDWND 196
KD++ QE PL E + + EE P+L ++K T E K +L +
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKK-------PTPEDKKLLPEAKT 1254
Query: 197 SIPESVH---LKAGERISQKSAENGRGGRVL-KPVRPLLLPRAAGEPLPTQRGAQEKMGT 252
S PE LK+ +I+++ E GRV K V+ P+ E LP+ G + +
Sbjct: 1255 SAPEEQKHDLLKSQVQIAEEKLE----GRVAPKTVQEGKQPQTKMEGLPS--GTPQSL-- 1306
Query: 253 PAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQESK--TLPAQACTR 310
P E + + + P A +EP GK+ K++ K T +Q
Sbjct: 1307 PKEDDKTTKTIKEQPQP---PCTAKPDQVEP-------GKEKTEKEDDKSDTSSSQQPKS 1356
Query: 311 SFSLRKTNSNKDGDQHSPGRNQSSAFSPPDPALR--------THSLPNRPSKVFPALRSP 362
L T + DG S G S + L+ S P+ PS + L S
Sbjct: 1357 PQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDL-AKLEST 1415
Query: 363 PCSKIEDVPTLL------EKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQ 416
S +E + L +K E P+ K +K SL +L + E ++ES++
Sbjct: 1416 VLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITIS--EEEIKESQE 1473
Query: 417 RKDIRDLFGSPKRKVLP-----EDSAQALEKLL---QPFKSTSLRQAAPPPPPPPPPPPP 468
+ +D F ++ +P ++ ++ ++ + +P+ S+ +++ P P
Sbjct: 1474 ER--KDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPY--DSVEESSESENSPVPQRKR 1529
Query: 469 PPTAGGADSKNFP-------------LRAQVTEASSSASSTSSSSADEEFDPQLSLQLKE 515
+ G + S + +R Q+ E SA +S S D+EF + QLKE
Sbjct: 1530 RTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIE--MSADEDASGSEDDEF---IRNQLKE 1584
Query: 516 -KKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRG 574
+ +KK E K + + +RL R+ ++ I E A R
Sbjct: 1585 ISSSTESQKKEETKGKGKITAGKHRRL--------------TRKSSTSID----EDAGRR 1626
Query: 575 EADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQS-RLEQKLREKMLK 633
+ DEA E +L + K ESE L++ L ++ L + +K
Sbjct: 1627 HSWHDEDDEA--FDESPELKYRETK--SQESEELVVTGGGGLRRFKTIELNSTIADKYSA 1682
Query: 634 EESQKDEK-DLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESF 684
E SQK +EE E+ + + L DS E++ E + H SF
Sbjct: 1683 ESSQKKTSLYFDEEPEL---------EMESLTDSPEDRSRGEGSSSLHASSF 1725
Score = 33.1 bits (74), Expect = 0.89
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 12/106 (11%)
Query: 581 QDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLE--------QKLREKML 632
+ + QL E L LEK K R+ EL QE++ Q ++ Q +++ +L
Sbjct: 3209 KQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLL 3268
Query: 633 KEESQKDEKDLNEEQEVFTE----LMQVIEQRDKLVDSLEEQRIRE 674
++ ++ + QE + L Q+ + + +L LEEQ+IR+
Sbjct: 3269 FQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQ 3314
Score = 30.4 bits (67), Expect = 5.8
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 5/82 (6%)
Query: 494 SSTSSSSADEEFDPQLSLQLKEKKTLRRRKK-----LEKAMKQLVKQEELKRLYKAQAIQ 548
S TS SS DE+ D S + E K R+ + L ++ ++EEL+ + Q
Sbjct: 1730 SPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQ 1789
Query: 549 RQLEEVEERQRASEIQGVRLEK 570
+ E+E++QR S + + +K
Sbjct: 1790 EKQREIEQQQRKSSSKKSKKDK 1811
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 56.6 bits (135), Expect = 8e-08
Identities = 129/598 (21%), Positives = 215/598 (35%), Gaps = 74/598 (12%)
Query: 3 PPKDPSPSLPLPSSSSHSSSPPSSS--STSVSGNAPDGSSPPQMTASEPLSQVSRGHP-S 59
PP+ P P+ P P S+ PPS S S P + P +++P+SQ G P
Sbjct: 510 PPQQPGPAKPSPQQPG-STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ 568
Query: 60 PPTPN-FRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLSDPAEMTSDECQPAE 118
PPT + ++ +QG P+ I P E L P + + T ECQ
Sbjct: 569 PPTVSPSAKQPPSQGLPKTI------CPLCNTTELLLHVPEKANFN-----TCTECQTTV 617
Query: 119 APLGDIGSNHRDPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLVKEKLGL 178
L N PH K+ ++ G D + + + + PV +
Sbjct: 618 CSLCGFNPN---PHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSK 674
Query: 179 KKLVLTQEQKTMLLDWNDSIPESVHLKAGE------RISQKSAENGRGGRVLKPVRPLLL 232
Q Q+T D+ P+ KA E + Q + + +P L
Sbjct: 675 SS---PQPQQTS--PKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSL 729
Query: 233 PRAAGEPLPTQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGK 292
+ A P+ Q+K A A + P P + ++ + +P + +S
Sbjct: 730 SKPAPPKEPSVPSEQDK----APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS---- 781
Query: 293 KAWAKQESKTLPAQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSP---PDPA----LRT 345
K ++ E KT P KT+S K P + S F P PA + +
Sbjct: 782 KVQSQAEEKTTPP---------LKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS 832
Query: 346 HSLPNRPSKVFPALRSPPCSKIEDVPTLLEKVSLQENFPDAS-------KPPKKRISLFS 398
H P+ SK + P K E+ K+S + PDA PP R +
Sbjct: 833 HPGPSSESK--GQKQVDPVQKKEEPKKAQTKMSPK---PDAKPMPKGSPTPPGPRPTAGQ 887
Query: 399 SLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPP 458
++ +S + Q R ++ + +PK + P + + L F ++ QA+
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQ--PTTPQETVTGKLFGFGASIFSQASNL 945
Query: 459 PPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKT 518
P P + GA K P +Q + ST + P S+ +K++
Sbjct: 946 ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPP----APAKSIPVKKETK 1001
Query: 519 LRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEA 576
+KLE +Q + + K I+ E Q+A + +LEK+ + E+
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKA--VLPTKLEKSPKPES 1057
Score = 49.7 bits (117), Expect = 9e-06
Identities = 36/95 (37%), Positives = 45/95 (47%), Gaps = 9/95 (9%)
Query: 376 KVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVLPED 435
K SL E D PP I+L +L F S +++ + GSP LP
Sbjct: 2332 KSSLSETVFD--HPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPA- 2388
Query: 436 SAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPP 470
K F+S+SL +A PPPPPPPPPPPPP
Sbjct: 2389 ------KPRPFFRSSSLDISAQPPPPPPPPPPPPP 2417
Score = 42.4 bits (98), Expect = 0.001
Identities = 150/732 (20%), Positives = 258/732 (35%), Gaps = 130/732 (17%)
Query: 4 PKDPSPSL---PLPSSSSHSSSPPSSSSTSVSGNAP---DGSSPPQMTASEPLSQVSRGH 57
P P P L P+ ++S+ S S P TS +A D S P+ PL + H
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 58 PSPPTPNFRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLSDPAEMTSDECQPA 117
SP A A+ P L P PK P D A + D+ +
Sbjct: 714 GSPS-------AKAKQPPEADSLSKPAPPK---------EPSVPSEQDKAPVADDKPKQP 757
Query: 118 EA--PLGDIGSNHR---DPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLV 172
+ P D+ S+ P K +S ++ +P D K S + P
Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS------QSFPPTGE 811
Query: 173 KEKLGLKKLVLTQEQKTMLLDWNDSIPESVHLKAGERISQKSAENGRGGRVLKPVRPLLL 232
K K + + ++ ES K + + QK E + + P +P
Sbjct: 812 KVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV-QKKEEPKKAQTKMSP-KPDAK 869
Query: 233 PRAAGEPLPTQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGK 292
P G P P P + + VP P+ + + R SL L +
Sbjct: 870 PMPKGSPTP-----------PGPRPTAGQTVPTPQQSPKPQEQSRRFSLN--LGSITDAP 916
Query: 293 KAWAKQESKTLPAQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRP 352
K+ +T+ + S+ SN PG + S P ++ P++P
Sbjct: 917 KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG---PGAPMKQAPAPSQP 973
Query: 353 SKVFPALRSPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQ 412
P + PP S + P P S P KK ++ +L+ K+ ++
Sbjct: 974 ----PTSQGPPKSTGQAPPA-----------PAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
Query: 413 ESRQR-------KDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPP 465
+ + KD + L P++ VLP LEK +P + L + PP
Sbjct: 1019 KRTETEKKPPPIKDSKSLTAEPQKAVLPTK----LEKSPKPESTCPLCKTELNIGSKDPP 1074
Query: 466 -------------------PPPPPTA---------------GG--ADSKNFPLRAQVTEA 489
P P T G D + P +A
Sbjct: 1075 NFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKA 1134
Query: 490 SSSASSTSSSSADEEFDPQLSLQLKEKKTLR--RRKKLEKAMKQLVKQEELKRLYKAQAI 547
S T SSS PQ+ L K+++ ++ K + + +K+ + E++ +
Sbjct: 1135 SPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTD-- 1192
Query: 548 QRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESEL 607
Q+Q E E+ +AS +Q EK E +E ++ E K +LE+ K + +L
Sbjct: 1193 QKQEESKLEKDKASALQ----EKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKL 1248
Query: 608 LIMAQELELEDHQSRL--------EQKLREKMLKEESQKDEKDLNEEQEVFTELMQVI-E 658
L A+ E+ + L E+KL ++ + Q+ ++ + + + + Q + +
Sbjct: 1249 LPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPK 1308
Query: 659 QRDKLVDSLEEQ 670
+ DK +++EQ
Sbjct: 1309 EDDKTTKTIKEQ 1320
Score = 40.0 bits (92), Expect = 0.007
Identities = 64/284 (22%), Positives = 100/284 (35%), Gaps = 24/284 (8%)
Query: 196 DSIPESVHLKAGERISQKSAENGRGGRVLKPVR-PLLLPRAAGEPLPTQRGAQEKMGTPA 254
D P+S+ + E+I KS G G KP++ P P+ LP QR A A
Sbjct: 233 DGTPKSISSQQPEKI--KSQPPGTG----KPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
Query: 255 EQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAW--AKQESKTLPAQACTRSF 312
+ +GE P SP S P+ + G A ++S+ PA+ +
Sbjct: 287 DIVRGESVKPSLPSP----------SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPS 336
Query: 313 SLRKTNSNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRPSKVFPALRSPPCSKIEDVPT 372
L K + + G P + + P P + P+ P + P
Sbjct: 337 GLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG 396
Query: 373 LLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVL 432
+ + + Q P +KPP +++ L + +S + K G K
Sbjct: 397 VGKTPAQQ---PGPAKPPTQQVGTPKPLA-QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452
Query: 433 PEDSAQALEKLLQPFKSTS-LRQAAPPPPPPPPPPPPPPTAGGA 475
+ + P K S L A PPP P P PPP G+
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS 496
Score = 38.9 bits (89), Expect = 0.016
Identities = 135/663 (20%), Positives = 231/663 (34%), Gaps = 117/663 (17%)
Query: 2 SPPKDPSPSLPLPSSSSHSSSPPSSSSTSVSGNAPDGSSPPQMTASEPLSQVSRGHPSPP 61
SP KD +P L + PP ++ G+ P A +P S P+PP
Sbjct: 683 SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS-------PSAKAKQPPEADSLSKPAPP 735
Query: 62 ----TPNFRRRA-VAQGAPREIPLYLPHHP---------KPEWAEYCLVSPGEDGLSDPA 107
P+ + +A VA P++ + P KP+ + S E+ + P
Sbjct: 736 KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Query: 108 EMTSDECQPAEAPLGDIGS---NHRDPHPIW--------GKDRSWTGQ-ELSPLAGEDRE 155
+ S + + P G+ S + P P G GQ ++ P+ ++
Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP 855
Query: 156 KGST-------GARKEEEGGPVLVKEKLGLKKLVLTQEQK----------TMLLDWNDSI 198
K + A+ +G P + + V T +Q ++ L
Sbjct: 856 KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA 915
Query: 199 PESVHLKAGERISQKSAENGRGGRVLKPVRPLLLPRAAGEPLPTQRGAQEKMGTPAEQAQ 258
P+S E ++ K G G + L+ AG+P P +Q G P +QA
Sbjct: 916 PKSQPTTPQETVTGKLF--GFGASIFSQASNLI--STAGQPGPH---SQSGPGAPMKQAP 968
Query: 259 GERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQESKTLPAQACTRSFSLRKTN 318
P + P + A +K++P + T++ + K
Sbjct: 969 APSQPPTSQGPPKSTGQA-------------------PPAPAKSIPVKKETKAPAAEKLE 1009
Query: 319 SNKDGDQHSPGRNQSSAFSPPDPALRTHSLPNRPSKVFPALRSPPCSKIEDVPTLLEKVS 378
+ +P ++ P P + SL P K +PT LEK
Sbjct: 1010 PKAE---QAPTVKRTETEKKPPPIKDSKSLTAEPQKAV-------------LPTKLEKSP 1053
Query: 379 LQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFG-SPKRKVLPEDSA 437
P+++ P K + L + K +F + + + +L G +P +
Sbjct: 1054 K----PESTCPLCK-----TELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 438 QALEKLLQPFKSTSL---RQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSAS 494
L Q S L R+ P P P P P PT + P + ++ +
Sbjct: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
Query: 495 STSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELK-RLYKAQAIQRQLEE 553
T + E K K+TL +K+ + KQEE K KA A+Q +
Sbjct: 1165 KTEAEKVILE---------KVKETL-SMEKIPPMVTTDQKQEESKLEKDKASALQEKKPL 1214
Query: 554 VEERQRASEIQGVRL-EKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQ 612
EE++ E + +R EK E T ++ +LL E E+ K +S++ I +
Sbjct: 1215 PEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEE 1274
Query: 613 ELE 615
+LE
Sbjct: 1275 KLE 1277
Score = 37.0 bits (84), Expect = 0.062
Identities = 135/592 (22%), Positives = 228/592 (38%), Gaps = 112/592 (18%)
Query: 137 KDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLVKEKLGLKKLVLTQEQKTMLLDWND 196
KD++ QE PL E + + EE P+L ++K T E K +L +
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKK-------PTPEDKKLLPEAKT 1254
Query: 197 SIPESVH---LKAGERISQKSAENGRGGRVL-KPVRPLLLPRAAGEPLPTQRGAQEKMGT 252
S PE LK+ +I+++ E GRV K V+ P+ E LP+ G + +
Sbjct: 1255 SAPEEQKHDLLKSQVQIAEEKLE----GRVAPKTVQEGKQPQTKMEGLPS--GTPQSL-- 1306
Query: 253 PAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQESK--TLPAQACTR 310
P E + + + P A +EP GK+ K++ K T +Q
Sbjct: 1307 PKEDDKTTKTIKEQPQP---PCTAKPDQVEP-------GKEKTEKEDDKSDTSSSQQPKS 1356
Query: 311 SFSLRKTNSNKDGDQHSPGRNQSSAFSPPDPALR--------THSLPNRPSKVFPALRSP 362
L T + DG S G S + L+ S P+ PS + L S
Sbjct: 1357 PQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDL-AKLEST 1415
Query: 363 PCSKIEDVPTLL------EKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESFLQESRQ 416
S +E + L +K E P+ K +K SL +L + E ++ES++
Sbjct: 1416 VLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITIS--EEEIKESQE 1473
Query: 417 RKDIRDLFGSPKRKVLP-----EDSAQALEKLL---QPFKSTSLRQAAPPPPPPPPPPPP 468
+ +D F ++ +P ++ ++ ++ + +P+ S+ +++ P P
Sbjct: 1474 ER--KDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPY--DSVEESSESENSPVPQRKR 1529
Query: 469 PPTAGGADSKNFP-------------LRAQVTEASSSASSTSSSSADEEFDPQLSLQLKE 515
+ G + S + +R Q+ E SA +S S D+EF + QLKE
Sbjct: 1530 RTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIE--MSADEDASGSEDDEF---IRNQLKE 1584
Query: 516 -KKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRG 574
+ +KK E K + + +RL R+ ++ I E A R
Sbjct: 1585 ISSSTESQKKEETKGKGKITAGKHRRL--------------TRKSSTSID----EDAGRR 1626
Query: 575 EADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQS-RLEQKLREKMLK 633
+ DEA E +L + K ESE L++ L ++ L + +K
Sbjct: 1627 HSWHDEDDEA--FDESPELKYRETK--SQESEELVVTGGGGLRRFKTIELNSTIADKYSA 1682
Query: 634 EESQKDEK-DLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESF 684
E SQK +EE E+ + + L DS E++ E + H SF
Sbjct: 1683 ESSQKKTSLYFDEEPEL---------EMESLTDSPEDRSRGEGSSSLHASSF 1725
Score = 33.1 bits (74), Expect = 0.89
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 12/106 (11%)
Query: 581 QDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLE--------QKLREKML 632
+ + QL E L LEK K R+ EL QE++ Q ++ Q +++ +L
Sbjct: 3209 KQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLL 3268
Query: 633 KEESQKDEKDLNEEQEVFTE----LMQVIEQRDKLVDSLEEQRIRE 674
++ ++ + QE + L Q+ + + +L LEEQ+IR+
Sbjct: 3269 FQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQ 3314
Score = 30.4 bits (67), Expect = 5.8
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 5/82 (6%)
Query: 494 SSTSSSSADEEFDPQLSLQLKEKKTLRRRKK-----LEKAMKQLVKQEELKRLYKAQAIQ 548
S TS SS DE+ D S + E K R+ + L ++ ++EEL+ + Q
Sbjct: 1730 SPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQ 1789
Query: 549 RQLEEVEERQRASEIQGVRLEK 570
+ E+E++QR S + + +K
Sbjct: 1790 EKQREIEQQQRKSSSKKSKKDK 1811
>gi|171906559 peripheral benzodiazepine receptor-associated protein
1 isoform a [Homo sapiens]
Length = 1857
Score = 56.6 bits (135), Expect = 8e-08
Identities = 80/304 (26%), Positives = 135/304 (44%), Gaps = 23/304 (7%)
Query: 398 SSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVLP--------EDSAQALEKLLQPFKS 449
S+L KDK + +E R+ + L G + L +S + + +L +
Sbjct: 222 SALLAKDKQIAALQRECRELQARLTLVGKEGPQWLHVRDFDRLLRESQREVLRLQRQIAL 281
Query: 450 TSLRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQL 509
+ R+ P PP PP P AG A + P A E + + E+ QL
Sbjct: 282 RNQRETLPLPPSWPPGPALQARAG-APAPGAPGEATPQEDADNLPVILGEPEKEQRVQQL 340
Query: 510 SLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQ--RASEIQGVR 567
+L +K+ + E KQ +E +L +AQ +L E R RA+E + V
Sbjct: 341 ESELSKKRKKCESLEQEARKKQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVE 400
Query: 568 LEKA-LRGEADSGTQDEAQLLQ--EWFKLVLEK-NKLMRYESELLIMAQELELEDHQSRL 623
E A LRG+ TQ+ L+ + + LE +++++ E+ Q+LE+E Q+RL
Sbjct: 401 WENAELRGQLLGVTQERDSALRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARL 460
Query: 624 EQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFES 683
LREK +EE ++ ++ E Q +Q++E +DS+ + R+RE E ++
Sbjct: 461 --SLREK--QEEVRRLQQAQAEAQREHEGAVQLLE---STLDSM-QARVRELEEQCRSQT 512
Query: 684 FVFS 687
FS
Sbjct: 513 EQFS 516
>gi|195947369 junction-mediating and regulatory protein [Homo
sapiens]
Length = 988
Score = 56.2 bits (134), Expect = 1e-07
Identities = 66/288 (22%), Positives = 114/288 (39%), Gaps = 29/288 (10%)
Query: 351 RPSKVFPALRSPPCSKIEDVPTLLEKVSLQENFPDASKPPKKRISLFSSLRLKDKSFESF 410
R P L+ C + V + EK + + P + S ++L+D S
Sbjct: 708 RKGAASPVLQEDHCDSLPSVLQVEEKTE-EVGEGRVKRGPSQTTEPQSLVQLEDTSLTQL 766
Query: 411 LQESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPP 470
S + L ++ + + P S L PPPPPPPPPPPPPP
Sbjct: 767 EATSLPLSGVTSELPPTISLPLLNNNLEPCSVTINPLPSP-LPPTPPPPPPPPPPPPPPP 825
Query: 471 TAGGADS------KNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLR--RR 522
DS K+ P R + E S+++ S+ + +S + K +KT +R
Sbjct: 826 LPVAKDSGPETLEKDLP-RKEGNEKRIPKSASAPSAHLFDSSQLVSARKKLRKTAEGLQR 884
Query: 523 KKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEI-----QGVRLEKALRGEAD 577
+++ M +++ + + + QR L + ++ I +GV+L+K
Sbjct: 885 RRVSSPMDEVLASLKRGSFHLKKVEQRTLPPFPDEDDSNNILAQIRKGVKLKKV------ 938
Query: 578 SGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQEL--ELEDHQSRL 623
+ +L+E F L+ + + L R E L +E E ED + L
Sbjct: 939 -----QKDVLRESFTLLPDTDPLTRSIHEALRRIKEASPESEDEEEAL 981
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 55.8 bits (133), Expect = 1e-07
Identities = 50/195 (25%), Positives = 101/195 (51%), Gaps = 18/195 (9%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLY--KAQAIQRQLEEVEERQR 559
+E + + L+ +EKK ++ +K+ + ++L +QE R K +++L E E+ R
Sbjct: 272 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR 331
Query: 560 ASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMR-----YESELLIMAQEL 614
E + +R +K LR + + + E ++ ++ K+ ++ K+ R +E E + QE
Sbjct: 332 EQE-KELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 390
Query: 615 ELEDHQSRL---EQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDS----L 667
++ D + R+ +++LRE KEE ++++ + E+ E E ++ EQ K D
Sbjct: 391 KMRDQEERMWEQDERLRE---KEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Query: 668 EEQRIREKAEDQHFE 682
EE+RIRE+ + E
Sbjct: 448 EEERIREREKKMREE 462
Score = 53.5 bits (127), Expect = 6e-07
Identities = 42/187 (22%), Positives = 97/187 (51%), Gaps = 23/187 (12%)
Query: 514 KEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEV----------EERQRASEI 563
+++K LR +K+L + +Q+ +QEE ++++ + R+ EE +E+Q +
Sbjct: 332 EQEKELREQKELREQEEQMQEQEE--KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389
Query: 564 QGVRLEKALRGEADSGTQDEAQLLQEWFKL------VLEKNKLMRYESELLIMAQELELE 617
Q +R ++ E D +++ + ++E K+ + E+ K+ E + ++++ E
Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE 449
Query: 618 DHQSRLEQKLRE-----KMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRI 672
+ E+K+RE + +E+ QK E+++ E++E + ++ EQ++KL + + Q
Sbjct: 450 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 509
Query: 673 REKAEDQ 679
EK +Q
Sbjct: 510 EEKIWEQ 516
Score = 51.6 bits (122), Expect = 2e-06
Identities = 60/226 (26%), Positives = 108/226 (47%), Gaps = 40/226 (17%)
Query: 492 SASSTSSSSAD---EEFDPQ---LSLQLK---------EKKTLRRRKKL-----EKAMKQ 531
SA ST AD EE + LSL+L +KK ++KL EK+ Q
Sbjct: 186 SAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQ 245
Query: 532 LVKQEELKRLYKAQAI--QRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQE 589
L +E ++L +A+ + Q Q ++E E + EK +R + + + E +L ++
Sbjct: 246 LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ 305
Query: 590 WFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLR----------EKMLKEES--- 636
K+ ++ K+ R E L +EL ++ + R +++LR EKM ++E
Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMR 365
Query: 637 QKDEKDLNEEQEVFTELMQVIEQRDKLVDSLE-----EQRIREKAE 677
+++EK +E+ ++ + Q+ EQ K+ D E ++R+REK E
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411
Score = 51.6 bits (122), Expect = 2e-06
Identities = 39/168 (23%), Positives = 89/168 (52%), Gaps = 12/168 (7%)
Query: 514 KEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALR 573
+E+K R+ K+L + K+L +QE+ R Q++L E EE+ + E + E+ +R
Sbjct: 312 QEEKMWRQEKRLREQEKELREQEKELRE------QKELREQEEQMQEQEEKMWEQEEKMR 365
Query: 574 GEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLK 633
+ + + E +L ++ ++ ++ K+ E + + L ++ + R ++K+ E++ K
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK 425
Query: 634 ----EESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAE 677
++ Q+ EK +++E E ++ E+ K+ + EE+ +RE+ E
Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE--EEETMREQEE 471
Score = 51.2 bits (121), Expect = 3e-06
Identities = 45/187 (24%), Positives = 96/187 (51%), Gaps = 12/187 (6%)
Query: 503 EEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASE 562
E+ Q +Q +E+K + +K+ + +++++ R K + + Q+ E EE+ R E
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557
Query: 563 I----QGVRLEKALRGEADSGTQD------EAQLLQEWFKLVLEKNKLMRYESELLIMAQ 612
Q R+EK + E + T D E + ++E K + E+ ++MR + E + +
Sbjct: 558 QKMWDQEERMEKKTQ-EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 616
Query: 613 ELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRI 672
E E + EQ+ + + +E+ + E+ + E++E E ++ EQ++KL + E+ +
Sbjct: 617 EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH-EKMQE 675
Query: 673 REKAEDQ 679
+EK ++Q
Sbjct: 676 QEKMQEQ 682
Score = 50.8 bits (120), Expect = 4e-06
Identities = 44/183 (24%), Positives = 101/183 (55%), Gaps = 19/183 (10%)
Query: 502 DEEFDPQLSLQLKEKKTLRRRKKL----EKAMKQLVKQEELKRLYKAQAIQRQLEEVEER 557
++ ++ + +Q +E+K + +K+ EK +Q E+ ++L++ + +Q Q + E+
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQE 683
Query: 558 QRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELE 617
++ E + ++EK + E + T D+ ++ +E + + E+ K MR E E++ E E
Sbjct: 684 EKIWEQE--KMEKKTQ-EQEKKTWDQEKMREE--ESMREREKKMREEEEMM-----REQE 733
Query: 618 DHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVD---SLEEQRIRE 674
+ E+K++E+ +EE + E+ + E++E E ++ EQ++KL + E+++I E
Sbjct: 734 EKMQEQEEKMQEQ--EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWE 791
Query: 675 KAE 677
+ E
Sbjct: 792 QEE 794
Score = 50.1 bits (118), Expect = 7e-06
Identities = 45/207 (21%), Positives = 100/207 (48%), Gaps = 23/207 (11%)
Query: 485 QVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKA 544
Q+ E D+E + Q +EKKT + +K+ + ++ +++ E K +
Sbjct: 545 QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE--EERMREREKKMREEE 602
Query: 545 QAIQRQLEEVEERQRASEIQGVRL----EKALRGEADSGTQDEAQLLQE---WFKLVLEK 597
+ ++ Q E+++E++ + Q ++ EK E Q+E QE W + L +
Sbjct: 603 EMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662
Query: 598 NKLMRYESELLIMAQELELED----HQSRLEQKL---------REKMLKEESQKD-EKDL 643
K +E E + ++++ ++ Q ++E+K +EKM +EES ++ EK +
Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKM 722
Query: 644 NEEQEVFTELMQVIEQRDKLVDSLEEQ 670
EE+E+ E + ++++++ + EE+
Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEE 749
Score = 49.3 bits (116), Expect = 1e-05
Identities = 38/193 (19%), Positives = 98/193 (50%), Gaps = 22/193 (11%)
Query: 512 QLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKA 571
+++E++ +R R+K + ++ ++++E K + + + Q E+ ++QR E + E+
Sbjct: 445 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 504
Query: 572 LRGEADSGTQDEAQLLQEWFKLVLEKNKLMR-----------YESELLIMAQELELEDHQ 620
E + ++ + +++ ++ ++ K+ R +E E + QE ++ D +
Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564
Query: 621 SRLEQKLR----------EKMLKEESQKD-EKDLNEEQEVFTELMQVIEQRDKLVDSLEE 669
R+E+K + EKM +EE ++ EK + EE+E+ E + ++++++ + EE
Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624
Query: 670 QRIREKAEDQHFE 682
+ ++ + Q E
Sbjct: 625 KMWEQEEKMQEQE 637
Score = 48.5 bits (114), Expect = 2e-05
Identities = 36/175 (20%), Positives = 93/175 (53%), Gaps = 13/175 (7%)
Query: 512 QLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKA 571
+++E++ +R R+K + +++++++E K + + +Q Q E++ E++ + Q EK
Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQE---EKM 640
Query: 572 LRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRL--EQKLRE 629
E Q+E Q+ +L +K KL +E M ++ ++++ + ++ ++K+ +
Sbjct: 641 WEQEEKMWEQEEKMWEQQ--RLPEQKEKLWEHEK----MQEQEKMQEQEEKIWEQEKMEK 694
Query: 630 KMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEE--QRIREKAEDQHFE 682
K ++E + +++ E+E E + + + ++++ EE Q EK ++Q E
Sbjct: 695 KTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Score = 42.4 bits (98), Expect = 0.001
Identities = 35/182 (19%), Positives = 92/182 (50%), Gaps = 18/182 (9%)
Query: 512 QLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKA 571
+++E++++R R+K + +++++++E K + + +Q Q EE+ E++ Q ++ +
Sbjct: 708 KMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ 767
Query: 572 LRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELL-----IMAQELELEDHQSRL--- 623
R E + +QE K+ ++ K+ E ++ + QE ++ + ++
Sbjct: 768 QRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQ 827
Query: 624 -------EQKL---REKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIR 673
E+K+ EKM +E + +EK +E+++ + ++ Q +K+ + E+ R +
Sbjct: 828 EEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQ 887
Query: 674 EK 675
E+
Sbjct: 888 EE 889
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/144 (23%), Positives = 75/144 (52%), Gaps = 11/144 (7%)
Query: 511 LQLKEKKTLRRRKKL----EKAMKQLVKQEELKRLYKAQAIQRQ--LEEVEERQRASEIQ 564
+Q +E++ + +K+ EK +Q E+ ++L++ + +Q Q + E EE+ R E +
Sbjct: 743 MQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802
Query: 565 GVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLE 624
E+ +RG+ + E ++ + K+ ++ K+ E ++ QE ++E+ E
Sbjct: 803 MRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKM--WGQEEKMEEKMQGQE 860
Query: 625 QKLREKMLKEESQKDEKDLNEEQE 648
+K+RE +EE + +++ EQE
Sbjct: 861 EKMRE---QEEKMRGQEEKMREQE 881
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 55.8 bits (133), Expect = 1e-07
Identities = 56/202 (27%), Positives = 93/202 (46%), Gaps = 21/202 (10%)
Query: 390 PKKRISLFSSL-RLKDKSFESFLQESRQRK------DIRDLF---GSPKRK--VLPEDS- 436
P R+S+ S L R DK + LQE +Q++ ++R G+P V P S
Sbjct: 338 PGPRMSMTSILTRNMDKQRQKRLQEQKQQEGYDGGPNLRTKVWQRGTPSSSPYVSPRHSP 397
Query: 437 --AQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSAS 494
+ L K +Q +S L A PPPPPPPPPPPPP++ P + E
Sbjct: 398 WSSPKLPKKVQTVRSRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITR 457
Query: 495 STSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEV 554
+ + +E Q +LQ +KK ++ KK++K ++K E+K ++ ++++E+
Sbjct: 458 NIAEVIKQQE-SAQRALQNGQKK--KKGKKVKKQPNSILK--EIKNSLRS-VQEKKMEDS 511
Query: 555 EERQRASEIQGVRLEKALRGEA 576
L +A+RG +
Sbjct: 512 SRPSTPQRSAHENLMEAIRGSS 533
Score = 33.9 bits (76), Expect = 0.52
Identities = 34/124 (27%), Positives = 63/124 (50%), Gaps = 25/124 (20%)
Query: 536 EELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFK--- 592
EELK L +R+LE++E + G+R +K+L + +GT L+ W K
Sbjct: 28 EELKEL------ERELEDIEPDRNLPV--GLR-QKSLTEKTPTGTFSREALMAYWEKESQ 78
Query: 593 LVLEKNKLM--------RYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLN 644
+LEK +L + ESE +EL + S + +++ + +EESQ++E++ +
Sbjct: 79 KLLEKERLGECGKVAEDKEESE-----EELIFTESNSEVSEEVYTEEEEEESQEEEEEED 133
Query: 645 EEQE 648
++E
Sbjct: 134 SDEE 137
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/180 (29%), Positives = 94/180 (52%), Gaps = 28/180 (15%)
Query: 516 KKTLRRRKKLEKAMKQLVKQEELKRLYKA-----QAIQRQLEEVEER-----QRASEIQG 565
K+ +RRK+L K KQL +QEEL+R K ++ Q++LE V ++ RA+E +
Sbjct: 317 KEARQRRKELRK--KQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEK 374
Query: 566 VRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQ 625
RL+ TQ E LQ F LE+ KL+R + E + + ELE + R+ +
Sbjct: 375 KRLQ----------TQVE---LQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRV-R 420
Query: 626 KLREKMLK-EESQKDEKDLNEEQEVFTELM-QVIEQRDKLVDSLEEQRIREKAEDQHFES 683
+L + LK +E+ +DE+ +++E +L +++E+ LE+ + ++ Q E+
Sbjct: 421 ELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEA 480
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/203 (24%), Positives = 94/203 (46%), Gaps = 22/203 (10%)
Query: 476 DSKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQ 535
+SK L A V + A+S ++ + Q+ LQ + L R K + + M++ V Q
Sbjct: 349 ESKQQELEA-VRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQ 407
Query: 536 EELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDE------AQLLQE 589
+ +LE+ +R R E ++L++AL E + +E A+LL+E
Sbjct: 408 KS-----------SELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEE 456
Query: 590 WF--KLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQ 647
+ LEK L + ++ A++ ELE+ + EQ L+E M E+ ++ E + +
Sbjct: 457 ESSKRAELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAM--EQLEQLELERKQAL 514
Query: 648 EVFTELMQVIEQRDKLVDSLEEQ 670
E + E+ + +E S +++
Sbjct: 515 EQYEEVKKKLEMATNKTKSWKDK 537
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/186 (22%), Positives = 95/186 (51%), Gaps = 30/186 (16%)
Query: 508 QLSLQLKEKKTLRRRKKLEKAMKQLVKQEELK-------------RLYKAQAIQRQLEEV 554
Q + + K+++ RKKLE+A + ++E+ + L + + I++Q+EE
Sbjct: 345 QAANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEE- 403
Query: 555 EERQRASEIQG------------VRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMR 602
+ Q++SE++ ++L++AL E + QDE + +++ +LE+ R
Sbjct: 404 QVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQA-RQDE-ETVRKLQARLLEEESSKR 461
Query: 603 YESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDK 662
E E + Q+ ++ ++ ++ +++LKE++ ++ + E+ E+ E Q +EQ ++
Sbjct: 462 AELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLEQLEL--ERKQALEQYEE 519
Query: 663 LVDSLE 668
+ LE
Sbjct: 520 VKKKLE 525
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 55.5 bits (132), Expect = 2e-07
Identities = 75/308 (24%), Positives = 140/308 (45%), Gaps = 45/308 (14%)
Query: 392 KRISLFSSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTS 451
K+ ++L + S + L+ RQ D + + +R+ E+ Q +++L
Sbjct: 1455 KQAEAVTALEQQVASLDKHLRNQRQFMDEQ----AAEREHEREEFQQEIQRL-----EGQ 1505
Query: 452 LRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSADEEFDPQLSL 511
LRQAA P P P P G + LR ++ E + A S+ D Q+ +
Sbjct: 1506 LRQAAKPQPWGPRDSQQAPLDGEVELLQQKLREKLDEFNELAIQKESA------DRQVLM 1559
Query: 512 QLKEKKTLRR-----RKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGV 566
Q +E K L RKK+ + +++ KQ+ + + +++ E ++++Q +S +
Sbjct: 1560 QEEEIKRLEEMNINIRKKVAQLQEEVEKQKNI-----VKGLEQDKEVLKKQQMSSLLLAS 1614
Query: 567 RLEKALRG----EADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELE--LEDHQ 620
L+ L E SG+ E +Q L + + L+R ESE+L + ++LE D +
Sbjct: 1615 TLQSTLDAGRCPEPPSGSPPEGPEIQ----LEVTQRALLRRESEVLDLKEQLEKMKGDLE 1670
Query: 621 SRLEQKLREKM-LKEESQKDEKDLNEEQEVFTELMQV------IEQRDKLVDSLEEQRIR 673
S+ E+ L + L ++ + L E +E T L + IE+ +++L+E + R
Sbjct: 1671 SKNEEILHLNLKLDMQNSQTAVSLRELEEENTSLKVIYTRSSEIEELKATIENLQENQKR 1730
Query: 674 ---EKAED 678
EKAE+
Sbjct: 1731 LQKEKAEE 1738
Score = 43.9 bits (102), Expect = 5e-04
Identities = 61/259 (23%), Positives = 104/259 (40%), Gaps = 15/259 (5%)
Query: 439 ALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNFPLRAQVTEA---SSSASS 495
A+EK ++ F +TS PPP + +D F R + +A
Sbjct: 2306 AVEKDVEDFITTSFDSQETLSSPPPGLEGKADRSEKSDGSGFGARLSPGSGGPEAQTAGP 2365
Query: 496 TSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVE 555
+ +S F P L +KEK+ R K KA+ Q+V+ E + L ++ + E
Sbjct: 2366 VTPASISGRFQP-LPEAMKEKEV---RPKHVKALLQMVRDESHQILALSEGLAPPSGEPH 2421
Query: 556 ERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELE 615
++ EIQ + L E + D L + + EK + M+ EL +
Sbjct: 2422 PPRKEDEIQDISLHGGKTQEVPTACPDWRGDLLQVVQEAFEKEQEMQ-GVELQPRLSGSD 2480
Query: 616 LEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREK 675
L H S LE+ EK+++E+ EK L E + ++ + L L ++ +
Sbjct: 2481 LGGHSSLLER--LEKIIREQGDLQEKSL--EHLRLPDRSSLLSEIQALRAQLRMTHLQNQ 2536
Query: 676 AEDQHFESFVFS---RGCQ 691
+ QH + + S RG Q
Sbjct: 2537 EKLQHLRTALTSAEARGSQ 2555
Score = 36.6 bits (83), Expect = 0.081
Identities = 48/218 (22%), Positives = 100/218 (45%), Gaps = 24/218 (11%)
Query: 482 LRAQVTEASSSASSTSSSSAD---EEFDPQLSLQLKEKKTLRRRKKLE------KAMKQL 532
L++ + E+ + S S + E + L KE + ++LE +A++
Sbjct: 2609 LKSDLCESRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRALQSQ 2668
Query: 533 VKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGE--ADSGTQDEAQLLQEW 590
+++E+L+ L + + LEE+ Q RL AL+ E A Q E ++
Sbjct: 2669 LEEEQLRHLQRESQSAKALEELRASLETQRAQSSRLCVALKHEQTAKDNLQKELRIEHSR 2728
Query: 591 FKLVLEKNKLMRYESELLIMAQELELEDHQS-RLEQKLR-EKMLKEE--SQKDEKDLNEE 646
+ +L + + S+L + ++L E ++ L + LR E++L E+ + E ++++
Sbjct: 2729 CEALLAQER-----SQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQD 2783
Query: 647 QEVFTELMQVI-EQRDKLVDSLEEQRIREKAEDQHFES 683
+ L+Q + E++ ++VD Q + EK + Q S
Sbjct: 2784 TQAHHALLQKLKEEKSRVVDL---QAMLEKVQQQALHS 2818
Score = 34.3 bits (77), Expect = 0.40
Identities = 48/189 (25%), Positives = 82/189 (43%), Gaps = 17/189 (8%)
Query: 496 TSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAI----QRQL 551
+ S+ A EE L Q + L K E+ K +++E + +A+ + QL
Sbjct: 2681 SQSAKALEELRASLETQRAQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQL 2740
Query: 552 EEVEERQRASEIQGVRLEKALRGEADSGTQ-----DEAQLLQEWFKLVLEKNKLMRYESE 606
E+++ A + + + L +ALR E Q EA + Q+ KL +S
Sbjct: 2741 SELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKEEKSR 2800
Query: 607 LLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIE----QRDK 662
++ + LE Q+ Q+ L+ E+QK + L E+EV L +E Q+ +
Sbjct: 2801 VVDLQAMLEKVQQQALHSQQ----QLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRE 2856
Query: 663 LVDSLEEQR 671
L SLE +R
Sbjct: 2857 LRCSLERER 2865
Score = 30.8 bits (68), Expect = 4.4
Identities = 40/178 (22%), Positives = 79/178 (44%), Gaps = 21/178 (11%)
Query: 516 KKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEE------VEERQRA-SEIQGVRL 568
+K L K+ + MKQ +++E + +QR+ EE +E R++A SE Q +
Sbjct: 728 QKELNNAKQKTELMKQEFQRKETDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIIN 787
Query: 569 EKALRGEADSGTQDE--AQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQK 626
+ LR QD+ AQ+L L ++ +L + E +L D Q
Sbjct: 788 KFELREAEMRQLQDQQAAQILDLERSLTEQQGRLQQLEQDL--------TSDDALHCSQC 839
Query: 627 LREKMLKEESQKDEKDLNEE--QEVFTELMQVIEQRDKLVD--SLEEQRIREKAEDQH 680
RE ++ + + E+ ++ + +E+R ++ + S E+ ++A++QH
Sbjct: 840 GREPPTAQDGELAALHVKEDCALQLMLARSRFLEERKEITEKFSAEQDAFLQEAQEQH 897
Score = 29.6 bits (65), Expect = 9.8
Identities = 23/116 (19%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Query: 521 RRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGT 580
++++LE ++L+ L + +QA+ R + + + + + + L+ + T
Sbjct: 2971 QQRELEAMRQRLLSAARLLTSFTSQAVDRTVNDWTSSNEKAVMSLLHTLEELKSDLSRPT 3030
Query: 581 QDEAQL---LQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLK 633
+ ++ LQ F VL K+ + ++ + ++LEL S+LE+ L+ + K
Sbjct: 3031 SSQKKMAAELQFQFVDVLLKDNVSLTKALSTVTQEKLELSRAVSKLEKLLKHHLQK 3086
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,530,345
Number of Sequences: 37866
Number of extensions: 2210631
Number of successful extensions: 59195
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 914
Number of HSP's successfully gapped in prelim test: 1493
Number of HSP's that attempted gapping in prelim test: 25796
Number of HSP's gapped (non-prelim): 20540
length of query: 695
length of database: 18,247,518
effective HSP length: 109
effective length of query: 586
effective length of database: 14,120,124
effective search space: 8274392664
effective search space used: 8274392664
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.