Guide to the Human Genome
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Search of human proteins with 239753786

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753786 PREDICTED: hypothetical protein LOC100129786 [Homo
sapiens]
         (210 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753786 PREDICTED: hypothetical protein LOC100129786 [Homo ...   434   e-122
gi|169167301 PREDICTED: hypothetical protein LOC100129786 [Homo ...   434   e-122
gi|169166477 PREDICTED: hypothetical protein LOC100129786 [Homo ...   434   e-122
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        59   4e-09
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    53   2e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         53   2e-07
gi|157266334 tubby like protein 1 [Homo sapiens]                       52   3e-07
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          50   1e-06
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]            48   5e-06
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             48   5e-06
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    48   5e-06
gi|150170670 piccolo isoform 2 [Homo sapiens]                          47   9e-06
gi|150378539 piccolo isoform 1 [Homo sapiens]                          47   9e-06
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        47   9e-06
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                        47   9e-06
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        46   2e-05
gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo sa...    46   2e-05
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              46   3e-05
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           45   4e-05
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           45   4e-05
gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]        45   4e-05
gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]        45   4e-05
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti...    45   6e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     44   8e-05
gi|169166609 PREDICTED: similar to ribonucleic acid binding prot...    44   1e-04
gi|113415994 PREDICTED: similar to ribonucleic acid binding prot...    44   1e-04
gi|157785645 SPEG complex locus [Homo sapiens]                         44   1e-04
gi|6857826 RNA-binding protein S1, serine-rich domain [Homo sapi...    44   1e-04
gi|18379334 RNA-binding protein S1, serine-rich domain [Homo sap...    44   1e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   44   1e-04

>gi|239753786 PREDICTED: hypothetical protein LOC100129786 [Homo
           sapiens]
          Length = 210

 Score =  434 bits (1115), Expect = e-122
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 1   MPGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRA 60
           MPGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRA
Sbjct: 1   MPGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRA 60

Query: 61  RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ 120
           RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ
Sbjct: 61  RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ 120

Query: 121 ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR 180
           ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR
Sbjct: 121 ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR 180

Query: 181 TTHLLGVFRVLKTQERKRLEEEVKMSQKVE 210
           TTHLLGVFRVLKTQERKRLEEEVKMSQKVE
Sbjct: 181 TTHLLGVFRVLKTQERKRLEEEVKMSQKVE 210


>gi|169167301 PREDICTED: hypothetical protein LOC100129786 [Homo
           sapiens]
          Length = 210

 Score =  434 bits (1115), Expect = e-122
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 1   MPGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRA 60
           MPGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRA
Sbjct: 1   MPGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRA 60

Query: 61  RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ 120
           RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ
Sbjct: 61  RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ 120

Query: 121 ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR 180
           ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR
Sbjct: 121 ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR 180

Query: 181 TTHLLGVFRVLKTQERKRLEEEVKMSQKVE 210
           TTHLLGVFRVLKTQERKRLEEEVKMSQKVE
Sbjct: 181 TTHLLGVFRVLKTQERKRLEEEVKMSQKVE 210


>gi|169166477 PREDICTED: hypothetical protein LOC100129786 [Homo
           sapiens]
          Length = 210

 Score =  434 bits (1115), Expect = e-122
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 1   MPGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRA 60
           MPGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRA
Sbjct: 1   MPGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRA 60

Query: 61  RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ 120
           RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ
Sbjct: 61  RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ 120

Query: 121 ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR 180
           ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR
Sbjct: 121 ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR 180

Query: 181 TTHLLGVFRVLKTQERKRLEEEVKMSQKVE 210
           TTHLLGVFRVLKTQERKRLEEEVKMSQKVE
Sbjct: 181 TTHLLGVFRVLKTQERKRLEEEVKMSQKVE 210


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 58.5 bits (140), Expect = 4e-09
 Identities = 50/171 (29%), Positives = 60/171 (35%), Gaps = 7/171 (4%)

Query: 11  SPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQ 70
           S    RR R     +    +R P T  +S   S  P  R R     P R R S    PT+
Sbjct: 545 SRNTQRRGRSRSARRGRSHSRSPATRGRS--RSRTPARRGRSRSRTPAR-RRSRSRTPTR 601

Query: 71  SMREPRTPAQSTRE-SWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQ 129
                RTPA+  R  S  P            +R  S SP  R   S R    T  RR R 
Sbjct: 602 RRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARR---SGRSRSRTPARRGRS 658

Query: 130 SPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR 180
             R P R   S    PA+ +   R  T A   R+    P   R   R + R
Sbjct: 659 RSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVR 709



 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 57/199 (28%), Positives = 77/199 (38%), Gaps = 37/199 (18%)

Query: 10   ESPGNPRRARESPGNQPTQSTREPRTPAQ--STRESWKPTHRARESPGNPRRARESPGNQ 67
            E P   R AR    + P   T+  RTP +  S+R S + T +AR S    RR+R +  + 
Sbjct: 1660 EHPPKSRTARRGSRSSPEPKTKS-RTPPRRRSSRSSPELTRKARLS----RRSRSASSSP 1714

Query: 68   PTQSMREPR----------TPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTR 117
             T+S   PR           PA+ +R S +   A   R   T +RG S SP  R  Q +R
Sbjct: 1715 ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774

Query: 118  ------------------ESQETDLRRARQSPRN--PRRARGSPGNRPAQSTREPRKPTN 157
                               SQ T  RR R   R+   RR RG  G       R+    T+
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTS 1834

Query: 158  AEHARAPETDPHEARGSHR 176
            +   R     P  +R   R
Sbjct: 1835 SRRRRGRSRTPPTSRKRSR 1853



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 46/174 (26%), Positives = 62/174 (35%), Gaps = 8/174 (4%)

Query: 7   RARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGN 66
           R R     P R   S    P +     RTP +    S  P  R R     P R R S   
Sbjct: 570 RGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPAR-RRSRTR 628

Query: 67  QPTQSMREPRTPAQSTRESWKPTHAEQARA----PETDQRGASESPGNRPTQSTRESQET 122
            P +     R+PA+ +  S   T A + R+    P    R  S +P  R   S R    T
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARR---SGRSRSRT 685

Query: 123 DLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHR 176
             RR R   R PRR R    +   +     R P     + +     +++R S R
Sbjct: 686 PARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQR 739



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 48/169 (28%), Positives = 70/169 (41%), Gaps = 17/169 (10%)

Query: 2    PGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRAR 61
            P  + ++R S   PRR+R   G+ P    +    P   +     P  +A      PRR+R
Sbjct: 1583 PEVDSKSRLS---PRRSRS--GSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSR 1637

Query: 62   ESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQE 121
                ++     R P     S+ ES  P H  ++R   T +RG+  S    P   T+    
Sbjct: 1638 SGSSSKG----RGPSPEGSSSTES-SPEHPPKSR---TARRGSRSS----PEPKTKSRTP 1685

Query: 122  TDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHE 170
               R +R SP   R+AR S  +R A S+ E R  T   H R+P     E
Sbjct: 1686 PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPE 1734



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 60/227 (26%), Positives = 80/227 (35%), Gaps = 37/227 (16%)

Query: 6    HRARESPGNPRRARESPGNQPTQSTREPRTPAQSTR---ESWKPT------HRARESPGN 56
            HR   S  +P  A +S  ++  +S   PRT   S R    S KP        R+R     
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTR 1783

Query: 57   PRRARESPGNQPTQSMREPRTPAQS--TRE--------SWKPTHAEQARAPETDQRGASE 106
              R R+  G+  + S R  R+ ++S  TR         S  P   E +R     +RG S 
Sbjct: 1784 TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR 1843

Query: 107  SPGNRPTQSTRESQETD-----LRRARQSPRNPRRARG---------SPGNRPAQSTREP 152
            +P   PT   R    T        R+R SP   RR+R          S       S R  
Sbjct: 1844 TP---PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRS 1900

Query: 153  RKPTNAEHARA-PETDPHEARGSHRFIPRTTHLLGVFRVLKTQERKR 198
            R  T+    R+     P   R S    P  T      R   T+ R R
Sbjct: 1901 RSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR 1947



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 40/170 (23%), Positives = 69/170 (40%), Gaps = 15/170 (8%)

Query: 11  SPGNPRRAR-ESPGNQP-TQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQP 68
           SP + RR   ++P ++P T ST+ P +P  +T++   P     +        R SP  + 
Sbjct: 297 SPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPER 356

Query: 69  TQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRAR 128
           + +  EP  P     E    +    A  P       S+ P N P++++         R R
Sbjct: 357 SSTGPEPPAPTPLLAERHGGSPQPLATTP------LSQEPVNPPSEASPT-------RDR 403

Query: 129 QSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFI 178
             P++P +   S  +  +  + +P K +    +      P  A GSHR I
Sbjct: 404 SPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 48/185 (25%), Positives = 70/185 (37%), Gaps = 11/185 (5%)

Query: 2    PGEEHRARESPGNPRRARESPGNQPTQSTREPRTPA--QSTRESWKPTHRARESPGNPRR 59
            P +  R+R SP   RR+R        + +R   +P   + +R     T R   S  +P  
Sbjct: 1860 PWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVS 1919

Query: 60   ARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPG-NRPTQSTRE 118
             R S    P  + R  R+   +TR       +     P T +R  S +P   R    +R 
Sbjct: 1920 RRRSRSRTPPVTRRRSRSRTPTTRR-----RSRSRTPPVTRRRSRSRTPPVTRRRSRSRT 1974

Query: 119  SQETDLR-RARQSP--RNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSH 175
            S  T  R R+R SP  R   R+R SP  R    +R          +R P      +R   
Sbjct: 1975 SPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRT 2034

Query: 176  RFIPR 180
              +PR
Sbjct: 2035 PLLPR 2039



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 43/195 (22%), Positives = 69/195 (35%), Gaps = 43/195 (22%)

Query: 12   PGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRR---ARESPG--- 65
            P  P R R S  + P      PRTP++ +R    P    R+  G P R   +  SPG   
Sbjct: 1411 PRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSP--GLRDGSGTPSRHSLSGSSPGMKD 1468

Query: 66   --NQPTQSMRE----------PRTPAQSTRESWKPTHAEQARAPETDQRGASESPGN--- 110
                P++   E          P+TP   +R    P    +   P+ ++ G+  S      
Sbjct: 1469 IPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528

Query: 111  -------------------RPTQSTRESQETDLR-RARQSPRNPRRARGSPGNRPAQSTR 150
                               +P+ S +E  E+D    ++   R P R R   G+ P   ++
Sbjct: 1529 ARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSK 1588

Query: 151  EPRKPTNAEHARAPE 165
                P  +    +PE
Sbjct: 1589 SRLSPRRSRSGSSPE 1603



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 6/160 (3%)

Query: 7   RARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGN 66
           R R     PRR R    +   +     RTP +  R S   + R  +S  + RR+R +   
Sbjct: 689 RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGR-SGSSSERKNKSRTSQRRSRSNSSP 747

Query: 67  QPTQSMREPRTPAQSTRESWKPTHAEQARAP-ETDQRGASESPGNRPTQSTRESQETDLR 125
           +    M++ R  ++ +R    P    ++R        G+S  P  +     R S+    +
Sbjct: 748 E----MKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQ 803

Query: 126 RARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPE 165
              +S   PRR+R S    P Q ++ P + +++  +  P+
Sbjct: 804 PKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK 843



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 50/180 (27%), Positives = 79/180 (43%), Gaps = 31/180 (17%)

Query: 7   RARESPGNPRRARES-------PGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRR 59
           R R  P +P +  +S       P  QPT+ +R     A S+ ES KP      +PG+ R 
Sbjct: 401 RDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRH----ASSSPESPKPA----PAPGSHRE 452

Query: 60  ARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASES--PGNRPTQSTR 117
              SP ++     R  R  + S   S +     ++R+P T +RG S S  P  R    +R
Sbjct: 453 ISSSPTSKNRSHGRAKRDKSHSHTPSRR---MGRSRSPATAKRGRSRSRTPTKRGHSRSR 509

Query: 118 ESQETDLRRARQ-----SPRNPRRARGS--PGNRPAQSTREPRKPTNAE----HARAPET 166
             Q    R A++     SP+   R+R    PG   +++T+   +  +A     H+R+P T
Sbjct: 510 SPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPAT 569



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 44/196 (22%), Positives = 66/196 (33%), Gaps = 29/196 (14%)

Query: 9   RESPGNPRRARESPGNQPTQSTRE-PRTPAQSTRESWK--PTHRARESPGNPRRARESPG 65
           R     P R   S    P +  R   RTPA+ +  S    P  R R     PRR R    
Sbjct: 646 RSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSR 705

Query: 66  NQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ----- 120
           +   +     RTP +  R         ++R  +   R  S     +   S+R S+     
Sbjct: 706 SLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSP 765

Query: 121 ------ETDLRRA---------RQSPRNPRRARGSPGNRPAQSTREPRK------PTNAE 159
                    LRR+         ++S   PRR+R       A+S   PR+      P   +
Sbjct: 766 RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQ 825

Query: 160 HARAPETDPHEARGSH 175
            ++ P    H +   H
Sbjct: 826 KSKTPSRQSHSSSSPH 841



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 51/163 (31%), Positives = 69/163 (42%), Gaps = 21/163 (12%)

Query: 7    RARESPGNPR-RARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPG 65
            R+R S    R R+R SP ++    +R P    + +R S  PT R R       R+R  P 
Sbjct: 1901 RSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSR-SRTPTTRRRS------RSRTPP- 1952

Query: 66   NQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASE-SPGNRPTQSTRESQETDL 124
               T+     RTP  + R S   T      +P T +R  S  SP  R    +R S  T  
Sbjct: 1953 --VTRRRSRSRTPPVTRRRSRSRT------SPITRRRSRSRTSPVTRRRSRSRTSPVTRR 2004

Query: 125  R-RARQSP--RNPRRARGSPGNRPAQSTREPRKPTNAEHARAP 164
            R R+R SP  R   R+R  P  R    +R P  P     +R+P
Sbjct: 2005 RSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSP 2047



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 37/153 (24%), Positives = 54/153 (35%), Gaps = 6/153 (3%)

Query: 7    RARESPGNPRRARESPGNQPTQSTRE---PRTPAQSTRESWKPTHRARESPGNPRRARES 63
            R R   G   R+     +  T S R     RTP  S + S     R   +P    R+R S
Sbjct: 1813 RRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRS---RSRTSPAPWKRSRSRAS 1869

Query: 64   PGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETD 123
            P        R P    + +R    P    ++R+  +  R  S S  +  ++    S+   
Sbjct: 1870 PATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPP 1929

Query: 124  LRRARQSPRNPRRARGSPGNRPAQSTREPRKPT 156
            + R R   R P   R S    P  + R  R  T
Sbjct: 1930 VTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 39/186 (20%), Positives = 70/186 (37%), Gaps = 35/186 (18%)

Query: 16  RRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQ----- 70
           RRARE+   QP     +P +  + +  S  PT + ++      R R S  + P +     
Sbjct: 155 RRAREA--KQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKS 212

Query: 71  ------------SMREPRTPAQSTRESWK-------------PTHAEQARAPETDQRGAS 105
                         R+ R+P   ++   K             P      R+   D   +S
Sbjct: 213 SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS 272

Query: 106 ESPGNRPTQSTRESQETDLRRARQSPRNPRRARG-SPGNRPAQSTREPRKPTNAEHARAP 164
           ++  +R   +  ++  T L     SP + RR  G +P + P   T   ++P++ E A   
Sbjct: 273 DTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEP--GTTSTQRPSSPETATKQ 330

Query: 165 ETDPHE 170
            + P+E
Sbjct: 331 PSSPYE 336



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 35/144 (24%), Positives = 63/144 (43%), Gaps = 12/144 (8%)

Query: 11   SPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQ 70
            S  +   +  S  +  + S+    + + S+    KP  +A   P +P++    PG + ++
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKP--PPGERRSR 2676

Query: 71   SMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQS 130
            S   PR P  S R+S   +++   R   + Q    +   +   + +R  Q  D R    S
Sbjct: 2677 S---PRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSR----S 2729

Query: 131  PRNPRRARGSPGNRPA--QSTREP 152
            P + RR R +P  RP   +S+R P
Sbjct: 2730 PSHKRR-RETPSPRPMRHRSSRSP 2752



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 37/170 (21%), Positives = 67/170 (39%), Gaps = 9/170 (5%)

Query: 11   SPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQ 70
            +P      RE    +PT + R+ R+ + S+  S   +  +  S  +   +  S  +  + 
Sbjct: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642

Query: 71   SMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQE---TDLRRA 127
            S                P  A   + P  ++R  S SP  +P  S R+S+    + + R 
Sbjct: 2643 SSSSSSPSPAKPGPQALPKPASPKKPPPGERR--SRSP-RKPIDSLRDSRSLSYSPVERR 2699

Query: 128  RQSPR-NPRRARGSPGNRPAQSTR--EPRKPTNAEHARAPETDPHEARGS 174
            R SP+ +PR  + S   R ++  +  + R P++      P   P   R S
Sbjct: 2700 RPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749



 Score = 35.8 bits (81), Expect = 0.027
 Identities = 40/163 (24%), Positives = 54/163 (33%), Gaps = 18/163 (11%)

Query: 17  RARESPG---NQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMR 73
           R+ + PG   ++ TQ     R+  +    S  P  R R     P R   S    P +   
Sbjct: 535 RSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRS 594

Query: 74  EPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRN 133
             RTP +    S         R P    R  S +P  R  +S   S      R+R   R 
Sbjct: 595 RSRTPTRRRSRS---------RTPARRGRSRSRTPARR--RSRTRSPVRRRSRSRSPARR 643

Query: 134 PRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHR 176
             R+R     R  +S    R  T A   R+    P    G  R
Sbjct: 644 SGRSRSRTPARRGRS----RSRTPARRGRSRSRTPARRSGRSR 682



 Score = 34.7 bits (78), Expect = 0.060
 Identities = 40/179 (22%), Positives = 72/179 (40%), Gaps = 23/179 (12%)

Query: 12   PGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARES-PGNPRRARE---SPGNQ 67
            P   RR+  S  +  + S+    + + S+      +     S P  P  A +   SP   
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585

Query: 68   PTQSMREPR----TPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETD 123
            P +++RE R    TPA+  R S   + +  + +  +    +S S  +  + S+  S  + 
Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645

Query: 124  LR---------RARQSPRNPRRARGSPGNRPAQSTREPRKPTNA-EHARAPETDPHEAR 172
                       +A   P +P++    PG R    +R PRKP ++   +R+    P E R
Sbjct: 2646 SSSPSPAKPGPQALPKPASPKKP--PPGER---RSRSPRKPIDSLRDSRSLSYSPVERR 2699



 Score = 34.3 bits (77), Expect = 0.079
 Identities = 32/141 (22%), Positives = 65/141 (46%), Gaps = 13/141 (9%)

Query: 36  PAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTPAQSTRESWKPT-HAEQA 94
           P +  RE+ +P   A E P      RES       S R P TP Q  ++  K      ++
Sbjct: 153 PQRRAREAKQP---APEPPKPYSLVRES------SSSRSP-TPKQKKKKKKKDRGRRSES 202

Query: 95  RAPETDQRGASESPGNR-PTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPR 153
            +P  +++ +S+   +R  ++S +    +   ++++  ++ +R R S    PA  +R   
Sbjct: 203 SSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKR-SRSTTPAPKSRRAH 261

Query: 154 KPTNAEHARAPETDPHEARGS 174
           + T+A+ A + +T    +R +
Sbjct: 262 RSTSADSASSSDTSRSRSRSA 282



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 42/183 (22%), Positives = 69/183 (37%), Gaps = 15/183 (8%)

Query: 3   GEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARE 62
           G      +S   PRR+R S    P Q +   +TP++ +  S  P H   +S   PR+   
Sbjct: 800 GSSQPKAKSRTPPRRSRSSSSPPPKQKS---KTPSRQSHSSSSP-HPKVKSGTPPRQGSI 855

Query: 63  SPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQET 122
           +      QS+    TP + +     P    ++R P       S  P  + +   R+S   
Sbjct: 856 TSPQANEQSV----TPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSR 911

Query: 123 DLRRARQSPRNPRRARGSPGNR--PAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR 180
                  SP+   +A  SP  R     S+  P + T+    R   +    +    R +PR
Sbjct: 912 S-----SSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPR 966

Query: 181 TTH 183
            +H
Sbjct: 967 YSH 969



 Score = 32.3 bits (72), Expect = 0.30
 Identities = 35/172 (20%), Positives = 60/172 (34%), Gaps = 19/172 (11%)

Query: 1    MPGEEHRARESPGNPRRARE----SPGNQPTQSTREPRTPAQSTRE-SWKPTHRARESPG 55
            + G     ++ P  P R R     SP  +    T  PR+ + S+ E + K     RE  G
Sbjct: 1459 LSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSG 1518

Query: 56   N------------PRRARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAP--ETDQ 101
            +            P   R   G+     ++   +P + +     P    + R P  +  +
Sbjct: 1519 SESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSR 1578

Query: 102  RGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPR 153
             G+S    ++   S R S+       +  PR   RA+    + P      PR
Sbjct: 1579 SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR 1630



 Score = 31.6 bits (70), Expect = 0.51
 Identities = 37/148 (25%), Positives = 56/148 (37%), Gaps = 11/148 (7%)

Query: 7    RARESPGNPRRARES--PGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESP 64
            R+R SP   RR+R    P  +    +R P  P + +R       R R     PR AR   
Sbjct: 2007 RSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTAR--- 2063

Query: 65   GNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDL 124
            G +        R+P    R S   + ++++R+  T     + S    P  +   S+ +  
Sbjct: 2064 GKRSL-----TRSPPAIRRRSASGSSSDRSRS-ATPPATRNHSGSRTPPVALNSSRMSCF 2117

Query: 125  RRARQSPRNPRRARGSPGNRPAQSTREP 152
             R   SP    R R      P  S+R P
Sbjct: 2118 SRPSMSPTPLDRCRSPGMLEPLGSSRTP 2145



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 35/168 (20%), Positives = 63/168 (37%), Gaps = 18/168 (10%)

Query: 7    RARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGN 66
            R+R  P  P ++R +    P+ S+R  + P+QS          A++ P +P  +  S  +
Sbjct: 2406 RSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP------AQDQPRSPVPSAFSDQS 2459

Query: 67   Q-------PTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRES 119
            +       P    +   + A +T  S    H      P     G   S    P  ST   
Sbjct: 2460 RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAP---GVPHSDVGEPPASTGAQ 2516

Query: 120  QETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETD 167
            Q + L  A   P   RR+  S  +  + S+      +++  + +  +D
Sbjct: 2517 QPSAL--AALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 4/164 (2%)

Query: 4   EEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARES 63
           E  R RE   N ++ RE    +  +  R+ +T  Q  RE  +   + RE   +  R R++
Sbjct: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171

Query: 64  PGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETD 123
             N+  Q  RE     Q  RE  +    E        +RG            T   ++TD
Sbjct: 172 ERNR--QKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTD 229

Query: 124 LRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETD 167
             R RQ  R   R R     R   S RE  +    E  R  + D
Sbjct: 230 RERDRQ--RKTEREREKQAERERASERETERDKERERERDRDRD 271



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 41/187 (21%), Positives = 68/187 (36%), Gaps = 14/187 (7%)

Query: 4   EEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARES 63
           +  R RE   + +R R     +  +  RE +T  +  R+  K  +R +E      R  E 
Sbjct: 78  KRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGER 137

Query: 64  PGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQET- 122
             ++ T   RE      + +E  + T  E+ R  E +++   E   NR  +  RE Q   
Sbjct: 138 GRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREK 197

Query: 123 -------------DLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPH 169
                        +  R R++     R R +   R  Q   E  +   AE  RA E +  
Sbjct: 198 ENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257

Query: 170 EARGSHR 176
             +   R
Sbjct: 258 RDKERER 264



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 49/225 (21%), Positives = 86/225 (38%), Gaps = 34/225 (15%)

Query: 8   ARESPGN---PRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESP 64
           +R  PG+   PRR      ++        R   +      +     RE+     R RE  
Sbjct: 27  SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86

Query: 65  GN----------QPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGA----SESPGN 110
            +          +  +  RE +T  +  R+  K  + ++ R  ET++ G      ++ G 
Sbjct: 87  RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQ 146

Query: 111 RPTQSTRESQ-----ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPE 165
           R  +  R+++     +TD  R RQ+ RN ++ R    NR  Q  RE  +    E+     
Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNR--QERRERERQREKEN---KT 201

Query: 166 TDPHEARGSHRFIPRTTHLLGVFRVLKTQERKRLEEEVKMSQKVE 210
            D H  RG  R   R T         +T+ +++ + E    +K E
Sbjct: 202 EDRHSERGRERERERETE-------TETERKRQTDRERDRQRKTE 239



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 37/146 (25%), Positives = 53/146 (36%), Gaps = 2/146 (1%)

Query: 7   RARESPGNPRRARESPGNQPTQSTRE-PRTPAQSTRESWKPTHRARESPGNPRRARESPG 65
           R RE      RA E    +  +  RE  R   +  R+  +     R+      R RE+  
Sbjct: 240 REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETER 299

Query: 66  NQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLR 125
            +  Q  RE        RE  +    E+ R  ET++    E    R  Q T   +E + +
Sbjct: 300 KRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQ-TEMDRERNRQ 358

Query: 126 RARQSPRNPRRARGSPGNRPAQSTRE 151
             R+  R   R R     R  QS RE
Sbjct: 359 TGREGRRQAERERERERERDRQSARE 384



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 14/155 (9%)

Query: 9   RESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQP 68
           RE      R RE    +  QS RE R   +  R+  +   R R++  +    RE+   + 
Sbjct: 361 REGRRQAERERERERERDRQSARE-REERERDRDRDRQKERERQTEKDRDGQRETEKQRE 419

Query: 69  TQSMREPRTPAQSTRESWKPTHAEQARAPETD-----QRGASESPGNRPTQSTRE----- 118
            +  RE     +  RE  K    E+ R  +TD     QR  S    N P ++ R      
Sbjct: 420 REKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQS 479

Query: 119 --SQETDLRRARQSPRNPRRARGS-PGNRPAQSTR 150
             ++ T   R + SP +P+ A    P  RPA+++R
Sbjct: 480 DPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASR 514


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 64/237 (27%), Positives = 86/237 (36%), Gaps = 51/237 (21%)

Query: 20  ESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPR-RARESPGNQPTQSMREPRTP 78
           E P     ++    R    S   S  P+ R R+   +PR R R SP   PT+  R P +P
Sbjct: 505 ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP-SP 563

Query: 79  AQSTRESWKPTHAEQARAPETDQRGASE-------------SPGNRPTQSTRESQETDLR 125
           A   R    PT   + R P    R  S              SP   P + T        R
Sbjct: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKR 623

Query: 126 RARQSPRNPRRARGSP-----------------------GNRPAQSTREPRKP-TNAEHA 161
           RA  SP   RR   SP                       G+ P++STRE R P  N  H+
Sbjct: 624 RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHS 683

Query: 162 -----RAPETD---PHEARGSHRFIPR----TTHLLGVFRVLKTQERKRLEEEVKMS 206
                RAP+T    P   RG+     R    +     + RV +T E K++++    S
Sbjct: 684 PSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740



 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 57/222 (25%), Positives = 83/222 (37%), Gaps = 61/222 (27%)

Query: 2   PGEEHRARESPGNPRRARESPGNQPTQSTREPRT---PAQSTRESWKPTHRARESPGNPR 58
           P    R R +P  P R R +P   P + +  PR    P Q       P  R   SP  P 
Sbjct: 563 PAPPPRRRRTPTPPPR-RRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPP 621

Query: 59  RARESP-----------------------------------GNQPTQSMREPRTPAQSTR 83
           + R SP                                   G+ P++S RE R+P  + R
Sbjct: 622 KRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKR 681

Query: 84  ESWKPTHAEQARAPETD------QRGASESPGNR--PTQSTRESQETD--------LRRA 127
            S  P    + RAP+T       +RGAS SP  R  P+ STR  +            + A
Sbjct: 682 HSPSP----RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737

Query: 128 RQSPRNPRRARG--SPGNRPAQSTREPRKPTNAEHARAPETD 167
             SP++ RR     S    P  + ++P  P +   +++P T+
Sbjct: 738 SPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTN 779



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 47/175 (26%), Positives = 78/175 (44%), Gaps = 21/175 (12%)

Query: 7   RARESPGNPRRA-----RESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRAR 61
           + R SP   RR+     +   G+ P++STRE R+P  + R S  P  RA ++  +P   R
Sbjct: 642 KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701

Query: 62  ESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGN-RPTQSTRESQ 120
               + P    +  ++P+ STR   + +   +   P+  ++ AS SP + R   S+R   
Sbjct: 702 RGASSSP----QRRQSPSPSTRPIRRVSRTPE---PKKIKKAASPSPQSVRRVSSSRSVS 754

Query: 121 ETDLRRARQSPRNPRRARGSPGNRPAQSTR-EPRKPTNAEHARAPETDPHEARGS 174
            +    A++ P  P     SP    + ST   P  P   + A++P   P   R S
Sbjct: 755 GSPEPAAKKPPAPP-----SPVQSQSPSTNWSPAVP--VKKAKSPTPSPSPPRNS 802



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 54/203 (26%), Positives = 68/203 (33%), Gaps = 31/203 (15%)

Query: 2   PGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPT-HRA---RESPG-- 55
           P   HR       P + R SP  Q +  TR+ R      R S K T H+    RESP   
Sbjct: 395 PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPA 454

Query: 56  -NPRRA---------------------RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQ 93
             PR+                      R     Q  QS  +  + + S  E  K +H + 
Sbjct: 455 PKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKN 514

Query: 94  ARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPR 153
                  +   S S    P +  +E+     RR   SP  P R R SP   PA   R  R
Sbjct: 515 GEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP-PPTRRRRSPS--PAPPPRRRR 571

Query: 154 KPTNAEHARAPETDPHEARGSHR 176
            PT     R P   P     S R
Sbjct: 572 TPTPPPRRRTPSPPPRRRSPSPR 594



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 38/172 (22%), Positives = 67/172 (38%), Gaps = 21/172 (12%)

Query: 10  ESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTH-------RARESPGNPRRARE 62
           + P   + +++    + T+     R+ ++S   S  P+H       R+R    +PRR R 
Sbjct: 257 KEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRR-RP 315

Query: 63  SPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQET 122
           SP  +P+   R P       R    P    ++R+P   +R +S S     + S+      
Sbjct: 316 SPRRRPSPRRRTP------PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSS---- 365

Query: 123 DLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGS 174
              R+R  P+ P +   SP  +  + +     P        P T P + R S
Sbjct: 366 ---RSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHS 414



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 44/177 (24%), Positives = 63/177 (35%), Gaps = 20/177 (11%)

Query: 2   PGEEHRARESPGNPRRARESPGNQPTQSTREP---RTPAQSTRESWKPTHRARESPGN-- 56
           P   HR+R    +PRR R SP  +P+   R P     P    R S  P  R R S  +  
Sbjct: 298 PRRRHRSRSRSYSPRR-RPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLS 356

Query: 57  -------PRRARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPG 109
                    R+R  P   P ++   PR   + +  +  P    +   P T       SP 
Sbjct: 357 GSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPT 416

Query: 110 NRPTQSTRESQETDLRRARQSP-RNPRRARGSPGNRPAQSTREPRKPTNAEHARAPE 165
            + +  TR+S      R   SP R   +     G    +S     KP   E + + E
Sbjct: 417 PQQSNRTRKS------RVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEE 467



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 46/186 (24%), Positives = 68/186 (36%), Gaps = 28/186 (15%)

Query: 4   EEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRE---SWKPTHRARE---SPGNP 57
           E+  +RE     R  R      P  S R   +P +  R+   S  P HR +    SP   
Sbjct: 158 EKESSREKRERSRSPRRRKSRSP--SPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPE 215

Query: 58  RRARESPGNQPTQSMREPRTP-AQSTRESWK-----PTHAEQARAPETDQRGASESPGNR 111
           ++ +     +P+  ++EP    A ST +  K     P    +  +PE + +   E    R
Sbjct: 216 KKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTR 275

Query: 112 PTQSTRESQETDLRRARQSPRNPR------------RARGSPGNRPAQSTREP--RKPTN 157
           P   +R    +  R    S   PR            R R SP  RP+   R P  R P  
Sbjct: 276 PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPP 335

Query: 158 AEHARA 163
             H R+
Sbjct: 336 PRHRRS 341



 Score = 35.8 bits (81), Expect = 0.027
 Identities = 43/189 (22%), Positives = 63/189 (33%), Gaps = 25/189 (13%)

Query: 4   EEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARES 63
           E+   + +  +  + R     Q  QS+ +  + + S  E  K +H      G  RR   S
Sbjct: 467 EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526

Query: 64  PGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETD 123
               P+   R+  T  +  R           R+P         SP   P    R +    
Sbjct: 527 RSASPSPRKRQKETSPRGRRR----------RSPSPPPTRRRRSPSPAPPPRRRRTPTPP 576

Query: 124 LRRARQSPRNPRRA------------RGSPGNRPAQSTREPRKPTNAEHARAPETDPHEA 171
            RR   SP   RR+            R SP   P + T  P  P      RA  + P + 
Sbjct: 577 PRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK---RRASPSPPPKR 633

Query: 172 RGSHRFIPR 180
           R SH   P+
Sbjct: 634 RVSHSPPPK 642



 Score = 27.3 bits (59), Expect = 9.6
 Identities = 15/57 (26%), Positives = 25/57 (43%)

Query: 114 QSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHE 170
           +S+RE +E      R+  R+P   R S   R  +     R P +   +R+P   P +
Sbjct: 160 ESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEK 216



 Score = 27.3 bits (59), Expect = 9.6
 Identities = 33/159 (20%), Positives = 57/159 (35%), Gaps = 37/159 (23%)

Query: 8   ARESPGNPRRARESPGNQP----TQSTREPRTPAQSTRESWKPTHRARESPGNPRRARES 63
           +R   G+P  A + P   P    +QS     +PA   +++  PT     SP  PR + + 
Sbjct: 750 SRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPT----PSPSPPRNSDQE 805

Query: 64  PGNQPTQSMREPR---------------------------TPAQSTRESWKPTHAEQARA 96
            G +  +  ++ +                           TPA     +      E   A
Sbjct: 806 GGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAA 865

Query: 97  PETDQRGASESPGNRP--TQSTRESQETDLRRARQSPRN 133
           PE  +   SE+  N     +  RE     +R+A+ SP++
Sbjct: 866 PEPKKETESEAEDNLDDLEKHLREKALRSMRKAQVSPQS 904


>gi|157266334 tubby like protein 1 [Homo sapiens]
          Length = 542

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 54/201 (26%), Positives = 74/201 (36%), Gaps = 42/201 (20%)

Query: 11  SPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPR--RARESPGNQP 68
           SP  PRR ++ P   P Q  R+ RT A    ES  PT      PG  R  R RE P   P
Sbjct: 24  SPEAPRRPKQRPA--PAQRLRKKRTEAP---ESPCPTGSKPRKPGAGRTGRPREEPSPDP 78

Query: 69  TQS----------MREPRTPAQSTRESWKPTHA-------EQARAPETDQRGASESPGNR 111
            Q+          +R+P    +  RE++    A       E+    E D+   +E    +
Sbjct: 79  AQARAPQTVYARFLRDPEAKKRDPRETFLVARAPDAEDEEEEEEEDEEDEEEEAEEKKEK 138

Query: 112 ----PTQSTRESQETDLRRARQSPRNPRRARGSPGNRP--------------AQSTREPR 153
               P +  RE    DL+  R   + PR   GSP   P                  R+ +
Sbjct: 139 ILLPPKKPLREKSSADLKERRAKAQGPRGDLGSPDPPPKPLRVRNKEAPAGEGTKMRKTK 198

Query: 154 KPTNAEHARAPETDPHEARGS 174
           K  + E  + P   P  AR S
Sbjct: 199 KKGSGEADKDPSGSPASARKS 219


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 46/165 (27%), Positives = 71/165 (43%), Gaps = 17/165 (10%)

Query: 14  NPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMR 73
           +P +AR+      ++S  + R  +Q    S +  HR   SP   R+ R+S  +   +  R
Sbjct: 466 SPNKARD---RSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHR 522

Query: 74  EPRTPAQSTRESWKPTHAEQARAPETDQ-RGASESPGNRPT--QSTRESQETDLRRARQS 130
             R+P+       K     Q+R+P  ++ R  S SP       QS   S+E D RR R S
Sbjct: 523 RSRSPS-------KERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWR-S 574

Query: 131 P---RNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEAR 172
           P   R  R++R S   R    +R P K +     RA   +   +R
Sbjct: 575 PSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSR 619



 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 18/162 (11%)

Query: 5   EHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESP 64
           +HR   SP   R+ R+S  +   +  R  R+P++  +       R   SP   R   +S 
Sbjct: 496 DHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQ------RRQSRSPNKERDRSQSR 549

Query: 65  GNQPTQSMREPRTPA-QSTRESWKPTHAEQAR-----APETDQRGASESPG-----NRPT 113
                +  R+ R+P+ +  R  W+    E+ R     + E      S SP      +RP 
Sbjct: 550 SPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609

Query: 114 QSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKP 155
            S++E   +  R   +   + +    S  + P+QST  PR P
Sbjct: 610 ASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST-VPRSP 650



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 41/174 (23%), Positives = 71/174 (40%), Gaps = 17/174 (9%)

Query: 5   EHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESP 64
           + R     G+P + R+   ++     R+ R    S++E     HR   SP   R+ R+S 
Sbjct: 481 KERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER---DHRRSRSPSKERQRRQSR 537

Query: 65  GNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQ---RGASESPGNRPTQSTRESQE 121
                +   + R+P++            Q+R+P  ++   R  S S      QS   S+E
Sbjct: 538 SPNKERDRSQSRSPSEEREH-------RQSRSPSKERDRRRWRSPSKERERRQSRSSSEE 590

Query: 122 TDLRRARQSPRNP--RRARGSPGNRPAQSTREPRKPTNAEHAR--APETDPHEA 171
            D  R+R   +     R R S   +    +R P K  N   +R  + E+DP ++
Sbjct: 591 RDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQS 644



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 34/133 (25%), Positives = 55/133 (41%), Gaps = 12/133 (9%)

Query: 19  RESPGNQPTQSTR---EPRTPAQ-STRESWKPTHRARESPGNPRRARESPGNQPTQ---- 70
           + +P N+P+  +R   + RTP++ ST        +A +   + RR   S G  P +    
Sbjct: 71  KRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSR 130

Query: 71  -SMREPR---TPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRR 126
            S R P    TP +      +P  A + R P + Q+G+      RP  S RE  ++  R 
Sbjct: 131 SSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRN 190

Query: 127 ARQSPRNPRRARG 139
             +    P    G
Sbjct: 191 LSKKSYRPPGGSG 203



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 42/175 (24%), Positives = 70/175 (40%), Gaps = 23/175 (13%)

Query: 12  PGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQS 71
           P  P   + +    P +S   P  PA S      P+        + +RA   P N+P+  
Sbjct: 26  PKPPASLKSTKSATPNRSL-VPTKPATSRNSVMSPSSSKSTKSTSTKRA---PSNRPSSR 81

Query: 72  MR---EPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRAR 128
            R   + RTP++ + ++ + + A +A      QR  + S G  P +          R +R
Sbjct: 82  SRVRSKARTPSRVSTDT-RTSKASKASDVRCHQRRGTHSRGRTPGR----------RGSR 130

Query: 129 QSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPRTTH 183
            S R+P RA     + P +      +P  A   R P +    +RG     PRT++
Sbjct: 131 SSKRSPSRA-----STPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSN 180



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 32/163 (19%), Positives = 64/163 (39%), Gaps = 5/163 (3%)

Query: 17  RARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPR 76
           R  +S  +   +S  + RTP +    +W        S  + R + +   ++ + S R+  
Sbjct: 328 RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKES 387

Query: 77  TPAQSTRESWKPTHAEQARAPETDQRGASESP----GNRPTQSTRESQETDLRRARQSPR 132
             +QS   + +  H+      +   R  S SP        ++S  ++++    R+    R
Sbjct: 388 GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447

Query: 133 NPRRARGSPGNRPAQSTREPRKPTNAEHARAPETD-PHEARGS 174
           +  R+R     R    +R P K  +   +R+P  +  H   GS
Sbjct: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGS 490



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 44/179 (24%), Positives = 70/179 (39%), Gaps = 16/179 (8%)

Query: 5   EHRARESPGNP--RRARESPGNQPTQS-TREPRTPAQSTRESWKPTHRARESPGNPRRAR 61
           +HR   SP     R    SP  Q   S +R P      +R       R R    +P +AR
Sbjct: 376 DHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKAR 435

Query: 62  E-----SPGNQPTQSMREPRTPAQSTRESWKPTHAE---QARAPETDQRGA---SESPGN 110
           +     SP     +S       A+    S  P  A    ++R+P  ++  +   S S   
Sbjct: 436 DCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKER 495

Query: 111 RPTQSTRESQETDLRRARQSP--RNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETD 167
              +S   S+E   R++R S   R+ RR+R     R  + +R P K  +   +R+P  +
Sbjct: 496 DHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEE 554



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 39/177 (22%), Positives = 69/177 (38%), Gaps = 14/177 (7%)

Query: 5   EHRARESPGNPRRARESPGNQPTQSTREPRTPAQS-----TRESWKPTHRARESPGNPRR 59
           +H    SP   R    S      +     R+P ++     +R  +K   R+R    +P +
Sbjct: 400 DHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSR--SPNK 457

Query: 60  ARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPT--QSTR 117
           AR+   +  ++S  + R  ++S   S +  H++     +      S SP       QS  
Sbjct: 458 ARD---HSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRS 514

Query: 118 ESQETDLRRAR--QSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEAR 172
            S+E D RR+R     R  R++R     R    +R P +      +R+P  +    R
Sbjct: 515 SSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRR 571



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 33/170 (19%), Positives = 69/170 (40%), Gaps = 7/170 (4%)

Query: 7   RARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGN 66
           R R    +P +AR+   ++     R+ R+ ++S  ++   +     +    R    SP  
Sbjct: 423 RDRSRSRSPNKARDCSRSRSPYKARD-RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSK 481

Query: 67  QPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRR 126
           +   S     +  +  R S  P+   Q R      R +S+   +R ++S  + ++    R
Sbjct: 482 ERDHSQLGSPSKERDHRRSRSPSKERQCR----QSRSSSKERDHRRSRSPSKERQRRQSR 537

Query: 127 ARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAP--ETDPHEARGS 174
           +    R+  ++R     R  + +R P K  +    R+P  E +  ++R S
Sbjct: 538 SPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSS 587



 Score = 36.6 bits (83), Expect = 0.016
 Identities = 35/150 (23%), Positives = 51/150 (34%), Gaps = 15/150 (10%)

Query: 2   PGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRAR 61
           P +E   R+S  +      S    P + +   R P  S++E      R     GN  ++R
Sbjct: 575 PSKERERRQSRSSSEERDHSRSRSPNKQSGYSR-PRASSKEKAHSRSRTPSKEGNHSQSR 633

Query: 62  ESPGNQPTQSMREPRTPAQSTRESWK--PTHAEQARAPETDQRGASESPGNRPTQSTRES 119
            S           PR+P       WK  PT         T  + +S SP   P+     S
Sbjct: 634 TSSKESDPSQSTVPRSP------DWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLS 687

Query: 120 QETDLRRARQSPRNPRRARGSPGNRPAQST 149
           Q+     A  S          PG R + S+
Sbjct: 688 QDDSQADATTSKAT------LPGERSSSSS 711



 Score = 35.8 bits (81), Expect = 0.027
 Identities = 36/177 (20%), Positives = 70/177 (39%), Gaps = 18/177 (10%)

Query: 18  ARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRT 77
           ++E   N    S+R+ ++  Q    S + ++   E     +   ++      QS  + R+
Sbjct: 227 SKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRS 286

Query: 78  PAQSTRESWKPTHA---------EQARAPETDQRGA-------SESPGNRPTQSTRESQE 121
           P +S   S K TH+           +RA    ++G        S+S  +   +S  +S+ 
Sbjct: 287 PRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRT 346

Query: 122 TDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTN--AEHARAPETDPHEARGSHR 176
               R+    RNP + R    +R +   R+ R  ++   E  R+    P++ R   R
Sbjct: 347 PRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSR 403



 Score = 33.9 bits (76), Expect = 0.10
 Identities = 33/143 (23%), Positives = 56/143 (39%), Gaps = 6/143 (4%)

Query: 37  AQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARA 96
           +Q  R S   +H   +S    R  R    +  +++  + R+ + S   S +  H   +  
Sbjct: 324 SQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSP 383

Query: 97  PETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTRE---PR 153
            +   R  S SP  +   S   S+  +  R R   R+P +AR    +R     R+    R
Sbjct: 384 RKESGRSQSGSPNKQRDHS--RSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSR 441

Query: 154 KPTNAEHARAPETDPHEARGSHR 176
            P  A   R+    P++AR   R
Sbjct: 442 SPYKARD-RSRSRSPNKARDHSR 463


>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 290

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 37/152 (24%), Positives = 62/152 (40%), Gaps = 3/152 (1%)

Query: 4   EEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARES 63
           E+ + RE   +  R RE   ++  +  R+        RE+   T R R+     ++ RE+
Sbjct: 128 EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET--ETERERDREREKQKERET 185

Query: 64  PGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRE-SQET 122
             ++  Q   E     Q+ RE  +    +  R  ETD+ G  E+   R  Q  R+  +E 
Sbjct: 186 ERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKER 245

Query: 123 DLRRARQSPRNPRRARGSPGNRPAQSTREPRK 154
           D  R R+  R   R +     R  +   E R+
Sbjct: 246 DRERDRKEERKKERKKERKKERKEKKKEEKRR 277



 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 45/174 (25%), Positives = 66/174 (37%), Gaps = 27/174 (15%)

Query: 5   EHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESP 64
           E R +E   N  R RE    + T+  R+     Q  RE  +   R RE   +  + RE  
Sbjct: 101 ERRRKEKETNRNRDRE----KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQ 156

Query: 65  GNQPTQSMREPRTPAQSTRESWKPTH------------AEQARAPETDQRGASESPGNRP 112
             +     RE  T  +  RE  K                E+ R  +TD+    E    R 
Sbjct: 157 TEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDR----ERDRQRK 212

Query: 113 TQSTRE-------SQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAE 159
           TQ+ R+        +ETD RR RQ  R+  + R    +R  +  +E +K    E
Sbjct: 213 TQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKE 266



 Score = 33.9 bits (76), Expect = 0.10
 Identities = 35/155 (22%), Positives = 59/155 (38%), Gaps = 21/155 (13%)

Query: 4   EEHRARESPGNPRRARESPGNQPTQSTREP--RTPAQSTRESWKPTHRARESPGNPRRA- 60
           E  R RE     +  ++  G + T++ RE       Q  RE+ +   R R++     R  
Sbjct: 144 ERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQT 203

Query: 61  -RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRES 119
            RE    + TQ+ R+  T  +  R              ETD+R   +   +R  +  R  
Sbjct: 204 DRERDRQRKTQTERQRETDREGER--------------ETDRRRERQRDRDRGKERDR-- 247

Query: 120 QETDLRRARQSPRNPRRARGSPGNRPAQSTREPRK 154
            E D +  R+  R   R +     +  +  RE +K
Sbjct: 248 -ERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 42/148 (28%), Positives = 60/148 (40%), Gaps = 11/148 (7%)

Query: 11   SPGNPRRARESPGNQPTQSTREPRTPAQS-TRESWKPTHRARESPGNPRRARESPGNQPT 69
            SP +P  +  SP   PT  +  P +P+ S T  S+ PT  +  SP +P  +  SP   PT
Sbjct: 1679 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS-YSPTSPSYSPTSPSYSPT 1737

Query: 70   QSMREPRTPAQS-TRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRAR 128
                 P +P  S T  ++ PT    +    T    +  SP   PT     S         
Sbjct: 1738 SPSYSPTSPNYSPTSPNYTPTSPSYS---PTSPSYSPTSPNYTPT-----SPNYSPTSPS 1789

Query: 129  QSPRNPRRARGSPGNRPAQSTREPRKPT 156
             SP +P  +  SP   P+     P+ PT
Sbjct: 1790 YSPTSPSYSPTSPSYSPSSPRYTPQSPT 1817



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 44/175 (25%), Positives = 67/175 (38%), Gaps = 17/175 (9%)

Query: 11   SPGNPRRARESPGNQPTQSTREPRTPAQS-TRESWKPTHRARESPGNPRRARESPGNQPT 69
            SP +P     SP   PT  +  P +P+ S T  S+ P+   R +P +P     SP   P+
Sbjct: 1770 SPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPS-SPRYTPQSPTYTPSSPSYSPS 1828

Query: 70   QSMREPRTPAQS-TRESWKPTHAE----QARAPETDQRGASESPGNRPTQSTRESQETDL 124
                 P +P  + T  S+ P+  E      +   T  + +  SP   PT  T        
Sbjct: 1829 SPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSP----- 1883

Query: 125  RRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHA-----RAPETDPHEARGS 174
               + SP +P  +  SP   P      P  PT +  +      +P   P   +GS
Sbjct: 1884 TTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGS 1938



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 37/146 (25%), Positives = 55/146 (37%), Gaps = 6/146 (4%)

Query: 11   SPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQ 70
            +P +P  +  SP   PT     P +P+ S           + SP +P+ +  SP   PT 
Sbjct: 1819 TPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTS 1878

Query: 71   SMREPRTPAQS-TRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQ 129
                P TP  S T  ++ PT         T  + +  SP   PT  + +   T    +  
Sbjct: 1879 PTYSPTTPKYSPTSPTYSPTSPVYT---PTSPKYSPTSPTYSPT--SPKYSPTSPTYSPT 1933

Query: 130  SPRNPRRARGSPGNRPAQSTREPRKP 155
            SP+    +  SPG  P   T     P
Sbjct: 1934 SPKGSTYSPTSPGYSPTSPTYSLTSP 1959



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 36/150 (24%), Positives = 54/150 (36%), Gaps = 6/150 (4%)

Query: 11   SPGNPRRARESPGNQPTQSTREPRTPAQ--STRESWKPTHRARESPGNPRRARESPGNQP 68
            SPG       +PG+  +     P  P+   +   S+ PT  A E         +SP   P
Sbjct: 1558 SPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSP 1617

Query: 69   TQSMREPRTPAQS-TRESWKPTHAEQA-RAPETDQRGASESPGNRPTQSTRESQETDLRR 126
            T     P +P+ S T  ++ PT    +  +P       S SP +     T  S       
Sbjct: 1618 TSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP--TS 1675

Query: 127  ARQSPRNPRRARGSPGNRPAQSTREPRKPT 156
               SP +P  +  SP   P   +  P  P+
Sbjct: 1676 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1705



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 2/91 (2%)

Query: 11   SPGNPRRARESPGNQPTQSTREPRTPAQS-TRESWKPTHRARESPGNPRRARESPGNQPT 69
            SP +P  +  +P   PT  T  P +P  + T   + PT     SP +P+ +  SP   PT
Sbjct: 1875 SPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTY-SPTSPKYSPTSPTYSPT 1933

Query: 70   QSMREPRTPAQSTRESWKPTHAEQARAPETD 100
                   +P         PT++  + A   D
Sbjct: 1934 SPKGSTYSPTSPGYSPTSPTYSLTSPAISPD 1964


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 35/154 (22%), Positives = 54/154 (35%), Gaps = 2/154 (1%)

Query: 12  PGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQS 71
           PG P R     GNQ   +   P  P +   +    +HR    PG P R     GNQ    
Sbjct: 96  PGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGP 155

Query: 72  MREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSP 131
              P  P     +  +   +  AR+P    +G  +  GN+P       +      A  +P
Sbjct: 156 PPHPGKPEGPPPQ--EGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNP 213

Query: 132 RNPRRARGSPGNRPAQSTREPRKPTNAEHARAPE 165
           + P+         P    +  R P  A+  + P+
Sbjct: 214 QQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPPQ 247



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 46/167 (27%), Positives = 62/167 (37%), Gaps = 24/167 (14%)

Query: 4   EEHRARESPGNPRRARESPGNQ-----PTQSTREPRTPAQSTRESWKPTHRARESPGNPR 58
           +  R    PG P+      GNQ     P     E R P    +    P H     PG P 
Sbjct: 46  QPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPH-----PGKPE 100

Query: 59  RARESPGNQ----PTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQ 114
           R     GNQ    P    +  R P Q   +S +P      +      +G ++S G  P  
Sbjct: 101 RPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPP-PPPGKPERPPPQGGNQSQGPPPHP 159

Query: 115 STRES---QETDLRRARQSPRNPRRARGSP---GNRPAQSTREPRKP 155
              E    QE +  R+ +SP  P + +G P   GN+P Q    P KP
Sbjct: 160 GKPEGPPPQEGNKSRSARSP--PGKPQGPPQQEGNKP-QGPPPPGKP 203



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 31/119 (26%), Positives = 42/119 (35%), Gaps = 6/119 (5%)

Query: 4   EEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARES 63
           + HR    PG P R     GNQ       P  P     +    +  AR  PG P+   + 
Sbjct: 130 QSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQ 189

Query: 64  PGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESP--GNRPTQSTRESQ 120
            GN+P Q    P  P         P   +Q +AP   +      P  G RP +  +  Q
Sbjct: 190 EGNKP-QGPPPPGKPQGPPPAGGNP---QQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQ 244



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 28/113 (24%), Positives = 41/113 (36%), Gaps = 13/113 (11%)

Query: 55  GNPRRARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQ 114
           G P   R   GNQP +    P  P     +   P    Q++ P          P  RP Q
Sbjct: 34  GKPEGRRPQGGNQPQRPPPPPGKP-----QGPPPQGGNQSQGPPPPPG----KPEGRPPQ 84

Query: 115 STRESQETDL---RRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAP 164
              +SQ       +  R  P+   +++G+P   P +  R P +  N  H   P
Sbjct: 85  GGNQSQGPPPHPGKPERPPPQGGNQSQGTP-PPPGKPERPPPQGGNQSHRPPP 136


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 47/197 (23%), Positives = 73/197 (37%), Gaps = 35/197 (17%)

Query: 3   GEEHRARESPGNPRRARESPG------------NQPTQSTREPRTPAQ-----STRESWK 45
           G E  + E PG P+   + PG              PTQ    P+  AQ     S  ++  
Sbjct: 377 GSEKPSSEQPG-PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435

Query: 46  PTHRARESPGNPRRARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGAS 105
           PT    + PG        PG  P Q     +T AQ T  +  P+       P   Q G +
Sbjct: 436 PTKTPVQQPG--------PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487

Query: 106 ESPGNRPTQSTRESQETDLRR--------ARQSPRNPRRARGSPGNRPAQSTREPRKPTN 157
           + P  +P  +   SQ+    +        A+ SP+ P   +  P  +P  +    ++P+ 
Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK-PPSQQPGSAKPSAQQPSP 546

Query: 158 AEHARAPETDPHEARGS 174
           A+ +    T P    GS
Sbjct: 547 AKPSAQQSTKPVSQTGS 563



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 30/140 (21%), Positives = 49/140 (35%), Gaps = 15/140 (10%)

Query: 2   PGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRAR 61
           PG+    +  P  P      P   P Q     + P Q    +  P+    + PG+ +   
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS----QQPGSTKPPP 511

Query: 62  ESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQE 121
           + PG         P  P+     S KP   +   A  + Q+ +   P  +  QST+   +
Sbjct: 512 QQPG---------PAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ--QSTKPVSQ 560

Query: 122 TDLRRARQSPRNPRRARGSP 141
           T   +  Q P     A+  P
Sbjct: 561 TGSGKPLQPPTVSPSAKQPP 580



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 28/171 (16%), Positives = 58/171 (33%), Gaps = 19/171 (11%)

Query: 9   RESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQP 68
           ++ P  P   ++ PG  P Q    P++ +    E      + +  P    +  + P   P
Sbjct: 212 QQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE------KIKSQPPGTGKPIQGPTQTP 265

Query: 69  TQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRAR 128
                +      ++R   K     +  + +      S+ P  +PT     +Q+    +++
Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQ 325

Query: 129 QSPRNP--------RRARGSPGN-----RPAQSTREPRKPTNAEHARAPET 166
             P  P        +     PG      +P  +T+ P +P       A +T
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQT 376



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 2   PGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARE-SPGNPRRA 60
           PG    + + PG+ +   + PG+    S ++P     S ++S KP  +     P  P   
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGS-AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTV 572

Query: 61  RESPGNQPTQSMREPRTPAQSTRE 84
             S    P+Q + +   P  +T E
Sbjct: 573 SPSAKQPPSQGLPKTICPLCNTTE 596



 Score = 27.3 bits (59), Expect = 9.6
 Identities = 34/159 (21%), Positives = 58/159 (36%), Gaps = 10/159 (6%)

Query: 1   MPGEEHRAR---ESPGNPRRARESPGNQPTQS-TREPRTPA---QSTRESWKPTHRARES 53
           +P E+ +A    + P  P+  + +     + S T +P  P+   QS  E  K T   +  
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE-KTTPPLKTD 798

Query: 54  PGNPRRARESPGNQ--PTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNR 111
              P ++    G +  P  S   PR  + S   S     +E     + D     E P   
Sbjct: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKA 858

Query: 112 PTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTR 150
            T+ + +     + +   +P  PR   G     P QS +
Sbjct: 859 QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPK 897


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 47/197 (23%), Positives = 73/197 (37%), Gaps = 35/197 (17%)

Query: 3   GEEHRARESPGNPRRARESPG------------NQPTQSTREPRTPAQ-----STRESWK 45
           G E  + E PG P+   + PG              PTQ    P+  AQ     S  ++  
Sbjct: 377 GSEKPSSEQPG-PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435

Query: 46  PTHRARESPGNPRRARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGAS 105
           PT    + PG        PG  P Q     +T AQ T  +  P+       P   Q G +
Sbjct: 436 PTKTPVQQPG--------PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487

Query: 106 ESPGNRPTQSTRESQETDLRR--------ARQSPRNPRRARGSPGNRPAQSTREPRKPTN 157
           + P  +P  +   SQ+    +        A+ SP+ P   +  P  +P  +    ++P+ 
Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK-PPSQQPGSAKPSAQQPSP 546

Query: 158 AEHARAPETDPHEARGS 174
           A+ +    T P    GS
Sbjct: 547 AKPSAQQSTKPVSQTGS 563



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 30/140 (21%), Positives = 49/140 (35%), Gaps = 15/140 (10%)

Query: 2   PGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRAR 61
           PG+    +  P  P      P   P Q     + P Q    +  P+    + PG+ +   
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS----QQPGSTKPPP 511

Query: 62  ESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQE 121
           + PG         P  P+     S KP   +   A  + Q+ +   P  +  QST+   +
Sbjct: 512 QQPG---------PAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ--QSTKPVSQ 560

Query: 122 TDLRRARQSPRNPRRARGSP 141
           T   +  Q P     A+  P
Sbjct: 561 TGSGKPLQPPTVSPSAKQPP 580



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 28/171 (16%), Positives = 58/171 (33%), Gaps = 19/171 (11%)

Query: 9   RESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQP 68
           ++ P  P   ++ PG  P Q    P++ +    E      + +  P    +  + P   P
Sbjct: 212 QQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE------KIKSQPPGTGKPIQGPTQTP 265

Query: 69  TQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRAR 128
                +      ++R   K     +  + +      S+ P  +PT     +Q+    +++
Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQ 325

Query: 129 QSPRNP--------RRARGSPGN-----RPAQSTREPRKPTNAEHARAPET 166
             P  P        +     PG      +P  +T+ P +P       A +T
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQT 376



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 2   PGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARE-SPGNPRRA 60
           PG    + + PG+ +   + PG+    S ++P     S ++S KP  +     P  P   
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGS-AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTV 572

Query: 61  RESPGNQPTQSMREPRTPAQSTRE 84
             S    P+Q + +   P  +T E
Sbjct: 573 SPSAKQPPSQGLPKTICPLCNTTE 596



 Score = 27.3 bits (59), Expect = 9.6
 Identities = 34/159 (21%), Positives = 58/159 (36%), Gaps = 10/159 (6%)

Query: 1   MPGEEHRAR---ESPGNPRRARESPGNQPTQS-TREPRTPA---QSTRESWKPTHRARES 53
           +P E+ +A    + P  P+  + +     + S T +P  P+   QS  E  K T   +  
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE-KTTPPLKTD 798

Query: 54  PGNPRRARESPGNQ--PTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNR 111
              P ++    G +  P  S   PR  + S   S     +E     + D     E P   
Sbjct: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKA 858

Query: 112 PTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTR 150
            T+ + +     + +   +P  PR   G     P QS +
Sbjct: 859 QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPK 897


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 42/168 (25%), Positives = 57/168 (33%), Gaps = 21/168 (12%)

Query: 10  ESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPT 69
           E P  P         +PT  T EP TP + T  S +      E P  P      P  +PT
Sbjct: 638 EKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPT 697

Query: 70  QSMRE-----------PRTPAQSTRESWKPTH-----AEQARAPETDQRGASESPGNRPT 113
            SM E           P  P   T +   PT       E+   P       +E P   P 
Sbjct: 698 ISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPE 757

Query: 114 QSTRESQETDLRRAR-----QSPRNPRRARGSPGNRPAQSTREPRKPT 156
           + T  +++  +   +     + P  P      P  +P  ST EP  PT
Sbjct: 758 KPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPT 805



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 43/159 (27%), Positives = 59/159 (37%), Gaps = 13/159 (8%)

Query: 10  ESPGNPRRARESPGNQPTQSTREPRTPAQS--------TRESWKPTHRARESPGNPRRAR 61
           E P  P+     P  +PT ST +P  P++         T  S KPT    E P  P    
Sbjct: 582 EKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPT-ILTEKPTIPSEKP 640

Query: 62  ESPGNQPTQSMREPRTPAQ--STRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRES 119
             P  +PT S  +P  P +  +T      T  E+   P       +E P     + T   
Sbjct: 641 TIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISM 700

Query: 120 QETDLRRARQ--SPRNPRRARGSPGNRPAQSTREPRKPT 156
           +ET +   +   SP  P      P     +ST  P KPT
Sbjct: 701 EETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPT 739



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 42/154 (27%), Positives = 61/154 (39%), Gaps = 10/154 (6%)

Query: 10  ESPGNPRRARESPGNQPTQSTREPRTPAQS-TRESWKPTHRARESPGNPRRARESPGNQP 68
           E P  P      P  +PT  T +P  P++  T  S KPT  + E P  P     +P  + 
Sbjct: 610 EKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTI-STEKPTVPTEEPTTPTEET 668

Query: 69  TQSMREPRTPAQS----TRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDL 124
           T SM EP  P +     T +   PT        ET    ++E P   P + T  +++  +
Sbjct: 669 TTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETII--STEKPTISPEKPTIPTEKPTI 726

Query: 125 --RRARQSPRNPRRARGSPGNRPAQSTREPRKPT 156
              ++  SP  P      P     + T  P KPT
Sbjct: 727 PTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPT 760



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 38/147 (25%), Positives = 53/147 (36%), Gaps = 21/147 (14%)

Query: 10  ESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPT 69
           E P  P      P  +PT S  +P TP +    S +      E P  P      P  +PT
Sbjct: 736 EKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPT 795

Query: 70  QSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQ 129
            S  EP TP + T  S      E+   P        E P     ++T   +ET +   + 
Sbjct: 796 ISTEEPTTPTEETTIS-----TEKPSIP-------MEKPTLPTEETTTSVEETTISTEKL 843

Query: 130 SPRNPRRARGSPGNRPAQSTREPRKPT 156
           +          P  +P  ST +P  PT
Sbjct: 844 T---------IPMEKPTISTEKPTIPT 861



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 35/134 (26%), Positives = 47/134 (35%), Gaps = 22/134 (16%)

Query: 10  ESPGNPRRARESPGNQPTQSTRE-----------PRTPAQSTRESWKPTHRARESPGNPR 58
           E P  P      P  +PT S  E           P  P   T +   PT ++  SP  P 
Sbjct: 680 EKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPT 739

Query: 59  RARESPG---NQPTQSMREPRTPAQS--------TRESWKPTHAEQARAPETDQRGASES 107
              E P     +PT S  +P TP +         T  + KPT   +     T++   S  
Sbjct: 740 TPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTE 799

Query: 108 PGNRPTQSTRESQE 121
               PT+ T  S E
Sbjct: 800 EPTTPTEETTISTE 813



 Score = 32.7 bits (73), Expect = 0.23
 Identities = 39/153 (25%), Positives = 53/153 (34%), Gaps = 14/153 (9%)

Query: 11   SPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQ 70
            SP  P  + E    +PT  T +P  P + T  S +      E P         P  +PT 
Sbjct: 909  SPEKPTISTE----KPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTI 964

Query: 71   SMREPRTPAQS-TRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQ 129
            S  +P  P +  T  + KPT   +     T++  A   P   PT        T L     
Sbjct: 965  STEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPT-------ATGLAALVM 1017

Query: 130  SPRNPRRARGSP--GNRPAQSTREPRKPTNAEH 160
            SP  P     S   G      +   R P NA +
Sbjct: 1018 SPHAPSTPMTSVILGTTTTSRSSTERCPPNARY 1050



 Score = 32.0 bits (71), Expect = 0.39
 Identities = 40/158 (25%), Positives = 60/158 (37%), Gaps = 23/158 (14%)

Query: 11  SPGNPRRARESPG--NQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQP 68
           SP +     E+ G    PT ST++P    +      KP+    E P  P+     P  +P
Sbjct: 546 SPVSSTGPSETTGLTENPTISTKKPTVSIE------KPSVTT-EKPTVPKEKPTIPTEKP 598

Query: 69  TQSMREPRTPAQS--------TRESWKPT-HAEQARAPETDQRGASESP---GNRPTQST 116
           T S  +P  P++         T  S KPT   E+   P       SE P     +PT  T
Sbjct: 599 TISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPT 658

Query: 117 RE--SQETDLRRARQSPRNPRRARGSPGNRPAQSTREP 152
            E  +   +   + + P  P      P  +P+  T +P
Sbjct: 659 EEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKP 696



 Score = 27.3 bits (59), Expect = 9.6
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 23/157 (14%)

Query: 22  PGNQPTQSTREPRT------------------PAQSTRESWKPTHRARESPGN---PRRA 60
           P  +PT  T E  T                  P  ST +   PT +   SP     P   
Sbjct: 818 PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEK 877

Query: 61  RESPGNQPTQSMREPRTPAQS-TRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRES 119
              P  +PT  + E     +  T  + KPT + +     T++          PT+ T  S
Sbjct: 878 LTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIS 937

Query: 120 QETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPT 156
            E  L    + P         P  +P  ST +P  PT
Sbjct: 938 TE-KLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPT 973


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 42/168 (25%), Positives = 57/168 (33%), Gaps = 21/168 (12%)

Query: 10  ESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPT 69
           E P  P         +PT  T EP TP + T  S +      E P  P      P  +PT
Sbjct: 638 EKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPT 697

Query: 70  QSMRE-----------PRTPAQSTRESWKPTH-----AEQARAPETDQRGASESPGNRPT 113
            SM E           P  P   T +   PT       E+   P       +E P   P 
Sbjct: 698 ISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPE 757

Query: 114 QSTRESQETDLRRAR-----QSPRNPRRARGSPGNRPAQSTREPRKPT 156
           + T  +++  +   +     + P  P      P  +P  ST EP  PT
Sbjct: 758 KPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPT 805



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 43/159 (27%), Positives = 59/159 (37%), Gaps = 13/159 (8%)

Query: 10  ESPGNPRRARESPGNQPTQSTREPRTPAQS--------TRESWKPTHRARESPGNPRRAR 61
           E P  P+     P  +PT ST +P  P++         T  S KPT    E P  P    
Sbjct: 582 EKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPT-ILTEKPTIPSEKP 640

Query: 62  ESPGNQPTQSMREPRTPAQ--STRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRES 119
             P  +PT S  +P  P +  +T      T  E+   P       +E P     + T   
Sbjct: 641 TIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISM 700

Query: 120 QETDLRRARQ--SPRNPRRARGSPGNRPAQSTREPRKPT 156
           +ET +   +   SP  P      P     +ST  P KPT
Sbjct: 701 EETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPT 739



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 42/154 (27%), Positives = 61/154 (39%), Gaps = 10/154 (6%)

Query: 10  ESPGNPRRARESPGNQPTQSTREPRTPAQS-TRESWKPTHRARESPGNPRRARESPGNQP 68
           E P  P      P  +PT  T +P  P++  T  S KPT  + E P  P     +P  + 
Sbjct: 610 EKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTI-STEKPTVPTEEPTTPTEET 668

Query: 69  TQSMREPRTPAQS----TRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDL 124
           T SM EP  P +     T +   PT        ET    ++E P   P + T  +++  +
Sbjct: 669 TTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETII--STEKPTISPEKPTIPTEKPTI 726

Query: 125 --RRARQSPRNPRRARGSPGNRPAQSTREPRKPT 156
              ++  SP  P      P     + T  P KPT
Sbjct: 727 PTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPT 760



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 38/147 (25%), Positives = 53/147 (36%), Gaps = 21/147 (14%)

Query: 10  ESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPT 69
           E P  P      P  +PT S  +P TP +    S +      E P  P      P  +PT
Sbjct: 736 EKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPT 795

Query: 70  QSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQ 129
            S  EP TP + T  S      E+   P        E P     ++T   +ET +   + 
Sbjct: 796 ISTEEPTTPTEETTIS-----TEKPSIP-------MEKPTLPTEETTTSVEETTISTEKL 843

Query: 130 SPRNPRRARGSPGNRPAQSTREPRKPT 156
           +          P  +P  ST +P  PT
Sbjct: 844 T---------IPMEKPTISTEKPTIPT 861



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 35/134 (26%), Positives = 47/134 (35%), Gaps = 22/134 (16%)

Query: 10  ESPGNPRRARESPGNQPTQSTRE-----------PRTPAQSTRESWKPTHRARESPGNPR 58
           E P  P      P  +PT S  E           P  P   T +   PT ++  SP  P 
Sbjct: 680 EKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPT 739

Query: 59  RARESPG---NQPTQSMREPRTPAQS--------TRESWKPTHAEQARAPETDQRGASES 107
              E P     +PT S  +P TP +         T  + KPT   +     T++   S  
Sbjct: 740 TPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTE 799

Query: 108 PGNRPTQSTRESQE 121
               PT+ T  S E
Sbjct: 800 EPTTPTEETTISTE 813



 Score = 32.7 bits (73), Expect = 0.23
 Identities = 39/153 (25%), Positives = 53/153 (34%), Gaps = 14/153 (9%)

Query: 11   SPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQ 70
            SP  P  + E    +PT  T +P  P + T  S +      E P         P  +PT 
Sbjct: 909  SPEKPTISTE----KPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTI 964

Query: 71   SMREPRTPAQS-TRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQ 129
            S  +P  P +  T  + KPT   +     T++  A   P   PT        T L     
Sbjct: 965  STEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPT-------ATGLAALVM 1017

Query: 130  SPRNPRRARGSP--GNRPAQSTREPRKPTNAEH 160
            SP  P     S   G      +   R P NA +
Sbjct: 1018 SPHAPSTPMTSVILGTTTTSRSSTERCPPNARY 1050



 Score = 32.0 bits (71), Expect = 0.39
 Identities = 40/158 (25%), Positives = 60/158 (37%), Gaps = 23/158 (14%)

Query: 11  SPGNPRRARESPG--NQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQP 68
           SP +     E+ G    PT ST++P    +      KP+    E P  P+     P  +P
Sbjct: 546 SPVSSTGPSETTGLTENPTISTKKPTVSIE------KPSVTT-EKPTVPKEKPTIPTEKP 598

Query: 69  TQSMREPRTPAQS--------TRESWKPT-HAEQARAPETDQRGASESP---GNRPTQST 116
           T S  +P  P++         T  S KPT   E+   P       SE P     +PT  T
Sbjct: 599 TISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPT 658

Query: 117 RE--SQETDLRRARQSPRNPRRARGSPGNRPAQSTREP 152
            E  +   +   + + P  P      P  +P+  T +P
Sbjct: 659 EEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKP 696



 Score = 27.3 bits (59), Expect = 9.6
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 23/157 (14%)

Query: 22  PGNQPTQSTREPRT------------------PAQSTRESWKPTHRARESPGN---PRRA 60
           P  +PT  T E  T                  P  ST +   PT +   SP     P   
Sbjct: 818 PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEK 877

Query: 61  RESPGNQPTQSMREPRTPAQS-TRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRES 119
              P  +PT  + E     +  T  + KPT + +     T++          PT+ T  S
Sbjct: 878 LTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIS 937

Query: 120 QETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPT 156
            E  L    + P         P  +P  ST +P  PT
Sbjct: 938 TE-KLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPT 973


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 41/165 (24%), Positives = 72/165 (43%), Gaps = 8/165 (4%)

Query: 21   SPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRA-RESPGNQPTQSMREPRTPA 79
            +P  +P+ ST +P TP  +++ +   T+R+  S   P      +P  QP+ S  +P TP 
Sbjct: 1411 APKLEPSTSTDQPVTPEPTSQATRGRTNRS--SVKTPETVVPTAPELQPSTSTDQPVTPE 1468

Query: 80   QSTRESWKPTHAEQARAPETDQRGASE----SPGNRPTQSTRESQETDLRRARQSPRNPR 135
             +++ +   T     + PET    A E    +  ++P  S   S+ T  R+ R S + P 
Sbjct: 1469 PTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPE 1528

Query: 136  R-ARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIP 179
                 +P  +P+ ST +P  P     A    T+    +     +P
Sbjct: 1529 TVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVP 1573



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 6/137 (4%)

Query: 21   SPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTPAQ 80
            +P   P+ ST +P TP  +++ +   T+R+      P     +P  QP+ S  +P T   
Sbjct: 1124 APEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEP-VVPTAPELQPSTSTDQPVTSEP 1182

Query: 81   STRESWKPTHAEQARAPETDQRGASE----SPGNRPTQSTRESQETDLRRARQSPRNPRR 136
            +++ +         + PET    A E    +  +RP  S   SQ T  R+ R S + P  
Sbjct: 1183 TSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEP 1242

Query: 137  -ARGSPGNRPAQSTREP 152
                +P  +P+ ST +P
Sbjct: 1243 VVPTAPELQPSTSTDQP 1259



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 40/176 (22%), Positives = 66/176 (37%), Gaps = 20/176 (11%)

Query: 21   SPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARE-------SPGNQPTQSMR 73
            +P  QP+ ST +P T         +PT++A     N    +        +P  +P+ S  
Sbjct: 1247 APELQPSTSTDQPVTS--------EPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTD 1298

Query: 74   EPRTPAQSTRESWKPTHAEQARAPETDQRGASE----SPGNRPTQSTRESQETDLRRARQ 129
             P TP  ++R +   T+    + PET    A E    +  ++P      S+ T  R    
Sbjct: 1299 RPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMS 1358

Query: 130  SPRNPRRARG-SPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPRTTHL 184
            S +NP      +P   P+ ST +P  P     A     +    +     +P    L
Sbjct: 1359 SVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKL 1414



 Score = 36.6 bits (83), Expect = 0.016
 Identities = 32/145 (22%), Positives = 58/145 (40%), Gaps = 6/145 (4%)

Query: 21   SPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTPAQ 80
            +P  QP+ S  +  TP  ++R +   T+R+      P     +P   PT S  +P TP  
Sbjct: 1575 APELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPV-VPTAPEPHPTTSTDQPVTPKL 1633

Query: 81   STRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARGS 140
            ++R + + T+    + P+  +  AS+     PT      Q        Q  ++      +
Sbjct: 1634 TSRATRRKTNRSSVKTPKPVEPAASDLEPFTPT-----DQSVTPEAIAQGGQSKTLRSST 1688

Query: 141  PGNRPAQSTREPRKPTNAEHARAPE 165
                P  +T E + P   +   +PE
Sbjct: 1689 VRAMPVPTTPEFQSPVTTDQPISPE 1713



 Score = 33.1 bits (74), Expect = 0.18
 Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 8/114 (7%)

Query: 29   STREPRTPAQSTRESW--KPTHRARESPG-NPRRARES-PGNQPTQSMREPRTPAQSTRE 84
            S   P  P  S  E +  KP  R R+S    P  A  + P   P+ S  +P TP  +++ 
Sbjct: 1086 SQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQA 1145

Query: 85   SWKPTHAEQARAPETDQRGASE----SPGNRPTQSTRESQETDLRRARQSPRNP 134
            +   T+    + PE     A E    +  ++P  S   SQ T  R++R S + P
Sbjct: 1146 TRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTP 1199


>gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo
           sapiens]
          Length = 685

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 47/194 (24%), Positives = 72/194 (37%), Gaps = 22/194 (11%)

Query: 1   MPGEEHRA---RESPGNPRRARESP----GNQPTQSTREPRTPAQSTRESWKPT--HRAR 51
           MPGE  +A     S  + R   + P      +P  ST  P  P  S   + K    H+A+
Sbjct: 283 MPGERIKAGSGNSSQPSLREGHDKPVFNGAGKPHSSTSSPSVPKTSASRTQKSAVEHKAK 342

Query: 52  ESPGNPRRARESPGNQPTQSMREP--RTPAQSTRESWKPTHAEQAR-----APETDQRGA 104
           +S  +P  +R  P   P    + P  R P  S+  +        AR      P   ++  
Sbjct: 343 KSLSHPSHSRPGPMVTPHNKAKSPGVRQPGSSSSSAPGQPSTGVARPTVSSGPVPRRQNG 402

Query: 105 SESPGNRPTQSTRESQETDLRRARQS------PRNPRRARGSPGNRPAQSTREPRKPTNA 158
           S S G   + S  +    D   +R++      P  P  + G PG   + S    R   ++
Sbjct: 403 SSSSGPERSISGSKKPTNDSNPSRRTVSGTCGPGQPASSSGGPGRPISGSVSSARPLGSS 462

Query: 159 EHARAPETDPHEAR 172
                P + PHE R
Sbjct: 463 RGPGRPVSSPHELR 476


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 48/187 (25%), Positives = 67/187 (35%), Gaps = 13/187 (6%)

Query: 3    GEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARE 62
            G   R   SP    R+  SP  +  +S+ E R  + S R    P+ R+  SP    R   
Sbjct: 1640 GPSQRRHHSPSE--RSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPS--ERRHR 1695

Query: 63   SPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQET 122
            SP  +  +   E R  + S R    P         E      SE   + P++    S   
Sbjct: 1696 SPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPS- 1754

Query: 123  DLRRARQSPRNPRRARGSPGNRPAQSTREPR--KPTNAEHARAPETDPH--EARGSHRFI 178
               R+  SP    R+  SP  R  +S  E R   P+   H    E   H    R  H  +
Sbjct: 1755 --ERSHCSP--SERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPL 1810

Query: 179  PRTTHLL 185
             R+ H L
Sbjct: 1811 ERSRHSL 1817



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 43/176 (24%), Positives = 66/176 (37%), Gaps = 13/176 (7%)

Query: 7    RARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGN 66
            R+  SP   +R   SP  +   S  E    + S R    P+ R   SP        S  +
Sbjct: 1604 RSWRSPS--QRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERS 1661

Query: 67   QPTQSMREPRTPAQ------STRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ 120
              + S R  R+P+Q      S R    P+        +   RG SE   + P   ++ S 
Sbjct: 1662 HRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSP---SKRSH 1718

Query: 121  ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHR 176
             +  RR+ +SP    R+  SP  R   S  E R  + +E +    ++      S R
Sbjct: 1719 RSPARRSHRSP--SERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSER 1772



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 45/183 (24%), Positives = 67/183 (36%), Gaps = 10/183 (5%)

Query: 3    GEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARE 62
            G   R R +P    R   SP  +  +S+ E R  + S R    P+ +   SP    R+  
Sbjct: 1552 GPSERTRHNPS--WRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPS--ERSWR 1607

Query: 63   SPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRE-SQE 121
            SP  +       P     S  E  +  H+   R+     +    SP  R  +S  E S  
Sbjct: 1608 SPSQR--NHCSPPERSCHSLSE--RGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHR 1663

Query: 122  TDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHE-ARGSHRFIPR 180
            +   R  +SP        S  +  + S R  R P+   H    E   H  ++ SHR   R
Sbjct: 1664 SSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPAR 1723

Query: 181  TTH 183
             +H
Sbjct: 1724 RSH 1726



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 43/182 (23%), Positives = 63/182 (34%), Gaps = 7/182 (3%)

Query: 7    RARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGN 66
            R   SP        S     + S R  R+P++ +  S   + R   SP        S  +
Sbjct: 1628 RGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRS--SSERRHRSPSQRSHRGPSERS 1685

Query: 67   QPTQSMREPRTPAQSTRE--SWKPTHAEQARAPETDQRGASESPGNRPTQSTRE-SQETD 123
              + S R  R+P+Q +    S +  H+   R+  +  R +  SP  R   S  E S  + 
Sbjct: 1686 HCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSP 1745

Query: 124  LRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPH--EARGSHRFIPRT 181
              R   SP        S  +  + S R  R P+   H    E   H    R  H    R 
Sbjct: 1746 SERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERR 1805

Query: 182  TH 183
             H
Sbjct: 1806 RH 1807



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 42/165 (25%), Positives = 60/165 (36%), Gaps = 12/165 (7%)

Query: 7    RARESPGNPR------RARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRA 60
            R+  SP   R      R+  SP  +   S  E R  + S R    P+ ++  SP    R+
Sbjct: 1740 RSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSE--RS 1797

Query: 61   RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ 120
              SP  +   S  E    +   R    P+     R+ E   R  SE    R    + +S 
Sbjct: 1798 HHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISE----RSHSPSEKSH 1853

Query: 121  ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPE 165
             + L R+R SP   R    S     + S R  R P+     R  E
Sbjct: 1854 LSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSE 1898



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 42/175 (24%), Positives = 68/175 (38%), Gaps = 38/175 (21%)

Query: 17   RARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSM--RE 74
            R+  SP  +  +S  E R  + S +    P+ R+  SP    R R SP  +   S+  R 
Sbjct: 1764 RSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSE--RRRHSPLERSRHSLLERS 1821

Query: 75   PRTPAQS-TRESWKPTHA------------------EQARAPETDQRGASES-------- 107
             R+P++  +  S++ +H                   E++R   +++RG S S        
Sbjct: 1822 HRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPS 1881

Query: 108  -------PGNRPTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKP 155
                    G R  +++  S  +   R R SP   R  R S  N  + S R  R P
Sbjct: 1882 ERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSP 1936



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 41/166 (24%), Positives = 56/166 (33%), Gaps = 19/166 (11%)

Query: 27   TQSTREP-RTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTPAQSTRES 85
            T S  +P RT  + +    K      E+     +   +PG +     R    P    + +
Sbjct: 1468 TASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRV--QARGRILPGSPVKRT 1525

Query: 86   W------KPTHAEQARAP---ETDQRGASESPGNRPT-----QSTRESQETDLRRARQSP 131
            W      K TH E        E   RG SE   + P+       +  SQ + L R   SP
Sbjct: 1526 WHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSP 1585

Query: 132  RNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPH--EARGSH 175
                    S  N  + S R  R P+   H   PE   H    RG H
Sbjct: 1586 SQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLH 1631



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 8/137 (5%)

Query: 17   RARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPR 76
            R+  SP  + +  + E R+  + +  S  P+ ++  SP    R+R SP  +   S     
Sbjct: 1820 RSHRSPSERRSHRSFE-RSHRRISERSHSPSEKSHLSP--LERSRCSPSERRGHSSSGKT 1876

Query: 77   TPAQSTRESWKPTHAEQARAPETDQRGASE----SPGN-RPTQSTRESQETDLRRARQSP 131
              + S R    P+   Q R  E   R + E    SP   RP + +  +  +   R+R+SP
Sbjct: 1877 CHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSP 1936

Query: 132  RNPRRARGSPGNRPAQS 148
                     PG RP+ S
Sbjct: 1937 LKEGLKYSFPGERPSHS 1953



 Score = 30.8 bits (68), Expect = 0.87
 Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 6/72 (8%)

Query: 7    RARESPGNPRRARESPGNQPTQSTREPRTPAQ------STRESWKPTHRARESPGNPRRA 60
            R+  SP   R+ R S  +  +   R   +P++      S R    P+ R+R SP      
Sbjct: 1883 RSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLK 1942

Query: 61   RESPGNQPTQSM 72
               PG +P+ S+
Sbjct: 1943 YSFPGERPSHSL 1954


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 10/162 (6%)

Query: 5    EHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESP 64
            +HR++ S    R+   S  N+ T   R  RTP++ +R       R   S G  R    SP
Sbjct: 1896 KHRSK-SRERKRKRSSSRDNRKTVRARS-RTPSRRSRSHTPSRRRRSRSVGRRRSFSISP 1953

Query: 65   GNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDL 124
              +     R  RTP++ +R     T + ++R P   +R  + S  +R     R S+    
Sbjct: 1954 SRRSRTPSRRSRTPSRRSR-----TPSRRSRTP--SRRSRTPSRRSRTPSRRRRSRSVVR 2006

Query: 125  RRARQ-SPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPE 165
            RR+   SP   RR+R     R ++S    ++  ++E  R+P+
Sbjct: 2007 RRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 48/211 (22%), Positives = 87/211 (41%), Gaps = 20/211 (9%)

Query: 3    GEEHRARESPGNPRRAR-ESPGNQPTQSTREPRTPAQSTRESWKPTHRA--RESPGNPRR 59
            GE+ + R+S    R  R +S  ++  + T E R+ A+  R S   +HR+  R    + RR
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARK-RSSKSKSHRSQTRSRSRSRRR 1870

Query: 60   ARESPGNQPTQSMRE--PRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTR 117
             R S     ++  R        +S +   K    ++ R+   D R    +    P++ +R
Sbjct: 1871 RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSR 1930

Query: 118  ESQETDLRRARQSPR------NPRRARGSPGNR---PAQSTREP--RKPTNAEHARAP-- 164
                +  RR+R   R      +P R   +P  R   P++ +R P  R  T +  +R P  
Sbjct: 1931 SHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990

Query: 165  -ETDPHEARGSHRFIPRTTHLLGVFRVLKTQ 194
                P   R S   + R +  +   R+ +++
Sbjct: 1991 RSRTPSRRRRSRSVVRRRSFSISPVRLRRSR 2021


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 10/162 (6%)

Query: 5    EHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESP 64
            +HR++ S    R+   S  N+ T   R  RTP++ +R       R   S G  R    SP
Sbjct: 1896 KHRSK-SRERKRKRSSSRDNRKTVRARS-RTPSRRSRSHTPSRRRRSRSVGRRRSFSISP 1953

Query: 65   GNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDL 124
              +     R  RTP++ +R     T + ++R P   +R  + S  +R     R S+    
Sbjct: 1954 SRRSRTPSRRSRTPSRRSR-----TPSRRSRTP--SRRSRTPSRRSRTPSRRRRSRSVVR 2006

Query: 125  RRARQ-SPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPE 165
            RR+   SP   RR+R     R ++S    ++  ++E  R+P+
Sbjct: 2007 RRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 48/211 (22%), Positives = 87/211 (41%), Gaps = 20/211 (9%)

Query: 3    GEEHRARESPGNPRRAR-ESPGNQPTQSTREPRTPAQSTRESWKPTHRA--RESPGNPRR 59
            GE+ + R+S    R  R +S  ++  + T E R+ A+  R S   +HR+  R    + RR
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARK-RSSKSKSHRSQTRSRSRSRRR 1870

Query: 60   ARESPGNQPTQSMRE--PRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTR 117
             R S     ++  R        +S +   K    ++ R+   D R    +    P++ +R
Sbjct: 1871 RRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSR 1930

Query: 118  ESQETDLRRARQSPR------NPRRARGSPGNR---PAQSTREP--RKPTNAEHARAP-- 164
                +  RR+R   R      +P R   +P  R   P++ +R P  R  T +  +R P  
Sbjct: 1931 SHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990

Query: 165  -ETDPHEARGSHRFIPRTTHLLGVFRVLKTQ 194
                P   R S   + R +  +   R+ +++
Sbjct: 1991 RSRTPSRRRRSRSVVRRRSFSISPVRLRRSR 2021


>gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]
          Length = 410

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)

Query: 73  REPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPR 132
           REPR          +P   +  R P  DQ    + P +RP    R  + +D  R R   R
Sbjct: 8   REPRA---------RPRERDPGRRPHPDQGRTHDRPRDRP-GDPRRKRSSDGNRRRDGDR 57

Query: 133 NPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARG 173
           +P R +   GNR     RE  +    +  R P  D H   G
Sbjct: 58  DPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAG 98



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 46/170 (27%), Positives = 66/170 (38%), Gaps = 16/170 (9%)

Query: 21  SPGNQPTQSTREPRTPAQSTRESWKPTH-RARESPGNPRRARESPGNQPTQSMREPRTPA 79
           S   +P    RE R P +        TH R R+ PG+PRR R S GN+     R+P    
Sbjct: 5   SGAREPRARPRE-RDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63

Query: 80  QSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARG 139
           +      +    E+ R  E D         +R     R  +     + RQS R    ARG
Sbjct: 64  ERDGNRDRNRDRERERERERDPDRGPRRDTHRDA-GPRAGEHGVWEKPRQS-RTRDGARG 121

Query: 140 -------SPGNRPAQSTREPRKPTNAEHA-RAPETDPHEARGSHRFIPRT 181
                   PG  P ++   P+     +   R PE++P     S R++P T
Sbjct: 122 LTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEP----PSERYLPST 167



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 37/151 (24%), Positives = 53/151 (35%), Gaps = 9/151 (5%)

Query: 3   GEEH-RARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRAR 61
           G  H R R+ PG+PRR R S GN+     R+P    +  R+  +  +R RE     R   
Sbjct: 28  GRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQE--RDGNRDRNRDRE---RERERE 82

Query: 62  ESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQE 121
             P   P +       P       W+     + R      RG +      P  +  E+ E
Sbjct: 83  RDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTR---DGARGLTWDAAAPPGPAPWEAPE 139

Query: 122 TDLRRARQSPRNPRRARGSPGNRPAQSTREP 152
               + +  P   R     P  R   ST  P
Sbjct: 140 PPQPQRKGDPGRRRPESEPPSERYLPSTPRP 170



 Score = 35.8 bits (81), Expect = 0.027
 Identities = 43/151 (28%), Positives = 54/151 (35%), Gaps = 30/151 (19%)

Query: 2   PGEEHRARESPGN--------PRRARESPGNQPTQSTRE-----PRTPAQSTRESWKPTH 48
           PG+  R R S GN        P R +E  GN+     RE      R P +  R   + TH
Sbjct: 38  PGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPR---RDTH 94

Query: 49  RARESPGNPRRARESPGNQPTQSMREPRTPAQS-TRESWKPTHAEQARAPETDQRGASES 107
           R       PR        +P QS    R  A+  T ++  P       APE  Q      
Sbjct: 95  R----DAGPRAGEHGVWEKPRQS--RTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGD 148

Query: 108 PGNRPTQSTRESQETDLRRARQSPRNPRRAR 138
           PG R  +S   S+       R  P  PR  R
Sbjct: 149 PGRRRPESEPPSE-------RYLPSTPRPGR 172


>gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]
          Length = 401

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 10/101 (9%)

Query: 73  REPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPR 132
           REPR          +P   +  R P  DQ    + P +RP    R  + +D  R R   R
Sbjct: 8   REPRA---------RPRERDPGRRPHPDQGRTHDRPRDRP-GDPRRKRSSDGNRRRDGDR 57

Query: 133 NPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARG 173
           +P R +   GNR     RE  +    +  R P  D H   G
Sbjct: 58  DPERDQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAG 98



 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 46/170 (27%), Positives = 66/170 (38%), Gaps = 16/170 (9%)

Query: 21  SPGNQPTQSTREPRTPAQSTRESWKPTH-RARESPGNPRRARESPGNQPTQSMREPRTPA 79
           S   +P    RE R P +        TH R R+ PG+PRR R S GN+     R+P    
Sbjct: 5   SGAREPRARPRE-RDPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQ 63

Query: 80  QSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARG 139
           +      +    E+ R  E D         +R     R  +     + RQS R    ARG
Sbjct: 64  ERDGNRDRNRDRERERERERDPDRGPRRDTHRDA-GPRAGEHGVWEKPRQS-RTRDGARG 121

Query: 140 -------SPGNRPAQSTREPRKPTNAEHA-RAPETDPHEARGSHRFIPRT 181
                   PG  P ++   P+     +   R PE++P     S R++P T
Sbjct: 122 LTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEP----PSERYLPST 167



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 37/151 (24%), Positives = 53/151 (35%), Gaps = 9/151 (5%)

Query: 3   GEEH-RARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRAR 61
           G  H R R+ PG+PRR R S GN+     R+P    +  R+  +  +R RE     R   
Sbjct: 28  GRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPERDQE--RDGNRDRNRDRE---RERERE 82

Query: 62  ESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQE 121
             P   P +       P       W+     + R      RG +      P  +  E+ E
Sbjct: 83  RDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTR---DGARGLTWDAAAPPGPAPWEAPE 139

Query: 122 TDLRRARQSPRNPRRARGSPGNRPAQSTREP 152
               + +  P   R     P  R   ST  P
Sbjct: 140 PPQPQRKGDPGRRRPESEPPSERYLPSTPRP 170



 Score = 35.8 bits (81), Expect = 0.027
 Identities = 43/151 (28%), Positives = 54/151 (35%), Gaps = 30/151 (19%)

Query: 2   PGEEHRARESPGN--------PRRARESPGNQPTQSTRE-----PRTPAQSTRESWKPTH 48
           PG+  R R S GN        P R +E  GN+     RE      R P +  R   + TH
Sbjct: 38  PGDPRRKRSSDGNRRRDGDRDPERDQERDGNRDRNRDRERERERERDPDRGPR---RDTH 94

Query: 49  RARESPGNPRRARESPGNQPTQSMREPRTPAQS-TRESWKPTHAEQARAPETDQRGASES 107
           R       PR        +P QS    R  A+  T ++  P       APE  Q      
Sbjct: 95  R----DAGPRAGEHGVWEKPRQS--RTRDGARGLTWDAAAPPGPAPWEAPEPPQPQRKGD 148

Query: 108 PGNRPTQSTRESQETDLRRARQSPRNPRRAR 138
           PG R  +S   S+       R  P  PR  R
Sbjct: 149 PGRRRPESEPPSE-------RYLPSTPRPGR 172


>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
           [Homo sapiens]
          Length = 213

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 40/164 (24%), Positives = 61/164 (37%), Gaps = 9/164 (5%)

Query: 4   EEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARES 63
           E  R R+   N  R R+    + T    E +   +  R+  + T R R+      R  E+
Sbjct: 45  ERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTET 104

Query: 64  PGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETD 123
              +  Q  RE        RE  K    E+    ETD+    ++   R T   R++++  
Sbjct: 105 DRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTED-- 162

Query: 124 LRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETD 167
               R   R   R R     R    T+E  + T+ E  R  ETD
Sbjct: 163 ----RHRERERERKRERERKR---ETKERERHTDMERERQRETD 199



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/178 (22%), Positives = 62/178 (34%), Gaps = 5/178 (2%)

Query: 32  EPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTPAQSTRESWKPTHA 91
           E +T  + T    +   R RE      R R+      T+     R   Q  RE  +    
Sbjct: 2   ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERD-RQRDRERNRERDR 60

Query: 92  EQARAPETDQRGASESPGNRPTQSTRESQ-ETDLRRARQSPRNPRRARGSPGNRPAQSTR 150
           ++ R  +TD+ G  +    R     RE++ E D  R         R R     R  +  R
Sbjct: 61  DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR 120

Query: 151 EPRKPTNAEHARAPETDPHEARGSHRFIPRTTHLLGVFRVLKTQERKRLEEEVKMSQK 208
           +  +    E  R  +TD    R   R   R        R  KT++R R  E  +  ++
Sbjct: 121 DREREKQKEMGRERQTDRETDRERERQAERERE---TGRERKTEDRHRERERERKRER 175



 Score = 34.3 bits (77), Expect = 0.079
 Identities = 35/137 (25%), Positives = 56/137 (40%), Gaps = 13/137 (9%)

Query: 3   GEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESP-------G 55
           GE  R RE   + +R  E   ++  ++ R   T  +  ++  +   R R+         G
Sbjct: 72  GERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMG 131

Query: 56  NPRRA-RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETD-QRGASESPGNRPT 113
             R+  RE+   +  Q+ RE  T  +   E     H E+ R  + + +R        R T
Sbjct: 132 RERQTDRETDRERERQAERERETGRERKTED---RHRERERERKRERERKRETKERERHT 188

Query: 114 QSTRESQ-ETDLRRARQ 129
              RE Q ETD +R RQ
Sbjct: 189 DMERERQRETDRKRDRQ 205


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 47/183 (25%), Positives = 85/183 (46%), Gaps = 27/183 (14%)

Query: 3   GEEHRARESPGNPRRARESPGNQPTQSTREPRTP----AQSTRESWKPTHRARESPG--- 55
           GEE    E+ G     +  P  +     +E ++P    A+S  E+  P     +SP    
Sbjct: 489 GEEE---EAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK 545

Query: 56  NPRRARESPGNQPTQSMREPRTP----AQSTRESWKPTHA-----EQARAP-ETDQRGAS 105
           +P +A+ SP  +  +S  E ++P    A+S  E   P  A     E+A++P E      +
Sbjct: 546 SPEKAK-SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKA 604

Query: 106 ESPGNRPTQSTRESQETDLRRARQSP---RNPRRARGSPGNRPAQSTREPRKPTNAEHAR 162
           +SP     +S  E+ ++ ++   +SP   ++P +A+ SP    A+S  + + P   E A+
Sbjct: 605 KSPVKEEAKSPAEA-KSPVKEEAKSPAEVKSPEKAK-SPTKEEAKSPEKAKSP-EKEEAK 661

Query: 163 APE 165
           +PE
Sbjct: 662 SPE 664



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 43/216 (19%), Positives = 83/216 (38%), Gaps = 17/216 (7%)

Query: 2   PGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQ--STRESWKPTHRARESPGNPRR 59
           P E     ++    +   +SP    +    E ++PA+  S  ++  PT    +SP   + 
Sbjct: 595 PAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654

Query: 60  ARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPE-----TDQRGASESPGNRPTQ 114
             +     P ++    +  A+S  ++  P  AE A++PE       +   S      P +
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAE-AKSPEKAKSPVKEEAKSPEKAKSPVK 713

Query: 115 STRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGS 174
              +S E      ++  + P +A+ SP    A+S   P K  + E A+  +    EA+  
Sbjct: 714 EEAKSPEKAKSPVKEEAKTPEKAK-SPVKEEAKS---PEKAKSPEKAKTLDVKSPEAK-- 767

Query: 175 HRFIPRTTHLLGVFRVLKTQERKRLEEEVKMSQKVE 210
               P              + +  ++EEVK  +K +
Sbjct: 768 ---TPAKEEARSPADKFPEKAKSPVKEEVKSPEKAK 800



 Score = 37.4 bits (85), Expect = 0.009
 Identities = 33/204 (16%), Positives = 84/204 (41%), Gaps = 6/204 (2%)

Query: 9   RESPGNPRRARESPGNQPTQSTREPRTP----AQSTRESWKPTHRARESPGNPRRARESP 64
           +E   +P +A+ SP  +  +S  + ++P    A+S  ++  P     +SP   +   +  
Sbjct: 643 KEEAKSPEKAK-SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEE 701

Query: 65  GNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDL 124
              P ++    +  A+S  ++  P   E+A+ PE  +    E   +     + E  +T  
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVK-EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD 760

Query: 125 RRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPRTTHL 184
            ++ ++    +    SP ++  +  + P K       +A      +A+   + IP+   +
Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV 820

Query: 185 LGVFRVLKTQERKRLEEEVKMSQK 208
               +  +  +  +++E  K +++
Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEE 844



 Score = 36.2 bits (82), Expect = 0.021
 Identities = 34/194 (17%), Positives = 72/194 (37%), Gaps = 24/194 (12%)

Query: 2   PGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRAR 61
           P +E     +   P +A+ SP  +  +S  + ++P +   ++ +     +E   +P +  
Sbjct: 769 PAKEEARSPADKFPEKAK-SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEE 827

Query: 62  ESPGN-------QPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQ 114
           E P         +  +  + P TP    ++  K   A +  AP+       E    +P +
Sbjct: 828 EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE 887

Query: 115 STRESQETDLRRARQSP----RNPRRARGSPGNRPAQST------------REPRKPTNA 158
           S  E+++ +    ++ P      P +       +P + T            +EP KP   
Sbjct: 888 SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK 947

Query: 159 EHARAPETDPHEAR 172
           + A   + D  E +
Sbjct: 948 KEAAPEKKDTKEEK 961



 Score = 35.0 bits (79), Expect = 0.046
 Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 7/107 (6%)

Query: 58  RRARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTR 117
           + A+E  G +      E    A+   E  K   AE+A +PE + +   +     P ++  
Sbjct: 476 KEAKEEEGKEEEGGEEEE---AEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEA-- 530

Query: 118 ESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAP 164
           +S E +  ++    ++P +A+ SP    A+S  E + P   E A++P
Sbjct: 531 KSPEKEEAKSPAEVKSPEKAK-SPAKEEAKSPPEAKSP-EKEEAKSP 575


>gi|169166609 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 6 [Homo sapiens]
          Length = 305

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 30/145 (20%), Positives = 54/145 (37%), Gaps = 1/145 (0%)

Query: 24  NQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTPAQSTR 83
           N    STR P    +  R   K   R+++       + +  G   T+  R   + + STR
Sbjct: 17  NNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTR 76

Query: 84  ESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARGSPGN 143
                T +  +        G+S S  +  + S+  S+ +    +  SP +P R R     
Sbjct: 77  SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP-SPSRRRHDNRR 135

Query: 144 RPAQSTREPRKPTNAEHARAPETDP 168
           R    ++ P++       R+P   P
Sbjct: 136 RSRSKSKPPKRDEKERKRRSPSPKP 160


>gi|113415994 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 2 [Homo sapiens]
          Length = 305

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 30/145 (20%), Positives = 54/145 (37%), Gaps = 1/145 (0%)

Query: 24  NQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTPAQSTR 83
           N    STR P    +  R   K   R+++       + +  G   T+  R   + + STR
Sbjct: 17  NNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTR 76

Query: 84  ESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARGSPGN 143
                T +  +        G+S S  +  + S+  S+ +    +  SP +P R R     
Sbjct: 77  SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP-SPSRRRHDNRR 135

Query: 144 RPAQSTREPRKPTNAEHARAPETDP 168
           R    ++ P++       R+P   P
Sbjct: 136 RSRSKSKPPKRDEKERKRRSPSPKP 160


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 7/89 (7%)

Query: 19  RESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTP 78
           RE P  QP  ++  PR PAQ       P+  A   P +PR  + SP   P Q    P +P
Sbjct: 281 REEPDLQPQLASEAPRRPAQPP-----PSKSALLPPPSPRVGKRSPPGPPAQPAATPTSP 335

Query: 79  AQSTRESWKP--THAEQARAPETDQRGAS 105
            + T+E   P  T  E+ R  ++   G S
Sbjct: 336 HRRTQEPVLPEDTTTEEKRGKKSKSSGPS 364



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 43/161 (26%), Positives = 57/161 (35%), Gaps = 14/161 (8%)

Query: 12  PGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQS 71
           P +PR  + SP   P Q    P +P + T+E   P     E     +     P    T  
Sbjct: 311 PPSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAE 370

Query: 72  MREPRTPAQ--STRESWKPTHAEQARAPET--------DQRGASESPGNRPTQSTRESQE 121
            R P+TP    S R S         RA           ++R  S    + P    R    
Sbjct: 371 SR-PQTPLSEASGRLSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLR--PW 427

Query: 122 TDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHAR 162
             LR+AR S   P+  RG+P   P  S  E R P +    R
Sbjct: 428 VPLRKAR-SLEQPKSERGAPWGTPGASQEELRAPGSVAERR 467



 Score = 34.7 bits (78), Expect = 0.060
 Identities = 34/131 (25%), Positives = 49/131 (37%), Gaps = 14/131 (10%)

Query: 49   RARESPGNPRRARESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESP 108
            R +ESP     +   P +    S  +P TP  +   +  P+ A Q  AP+  Q  A E P
Sbjct: 2160 RLQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPE-P 2218

Query: 109  GNRPTQSTRESQETDLRRARQSPRNP-----------RRARGSPGNRPAQSTREPRKPTN 157
               P ++++ +      +    P  P             A+G P   PA    EP KP  
Sbjct: 2219 RPEPVRASKPAPPPQALQTLALPLTPYAQIIQSLQLSGHAQG-PSQGPAAPPSEP-KPHA 2276

Query: 158  AEHARAPETDP 168
            A  AR     P
Sbjct: 2277 AVFARVASPPP 2287



 Score = 34.3 bits (77), Expect = 0.079
 Identities = 39/190 (20%), Positives = 61/190 (32%), Gaps = 28/190 (14%)

Query: 2    PGEEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRAR 61
            P ++      P   R ++ +P  Q  Q+   P TP     +S + +  A+     P    
Sbjct: 2210 PAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTPYAQIIQSLQLSGHAQGPSQGPAAPP 2269

Query: 62   ESPGNQPTQSMREPRTPAQSTRE-----SWKPTHAEQARAPETDQRGASESPGNRPTQST 116
              P        R    P  +  +        P  AE+AR P    R  S    +     +
Sbjct: 2270 SEPKPHAAVFARVASPPPGAPEKRVPSAGGPPVLAEKARVPTVPPRPGSSLSSSIENLES 2329

Query: 117  RESQETDLRRARQSP---------------RNPRRA--------RGSPGNRPAQSTREPR 153
                E   +R+R+SP               R P R         R SP   P +  R P 
Sbjct: 2330 EAVFEAKFKRSRESPLSLGLRLLSRSRSEERGPFRGAEEEDGIYRPSPAGTPLELVRRPE 2389

Query: 154  KPTNAEHARA 163
            +  + +  RA
Sbjct: 2390 RSRSVQDLRA 2399



 Score = 32.3 bits (72), Expect = 0.30
 Identities = 33/125 (26%), Positives = 42/125 (33%), Gaps = 11/125 (8%)

Query: 61  RESPGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQ 120
           RE P  QP  +   PR PAQ       P  ++ A  P    R    SP   P Q    + 
Sbjct: 281 REEPDLQPQLASEAPRRPAQ-------PPPSKSALLPPPSPRVGKRSPPGPPAQPA--AT 331

Query: 121 ETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFIPR 180
            T   R  Q P  P              +  P     AE    P+T   EA G    + R
Sbjct: 332 PTSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAE--SRPQTPLSEASGRLSALGR 389

Query: 181 TTHLL 185
           +  L+
Sbjct: 390 SPRLV 394



 Score = 32.3 bits (72), Expect = 0.30
 Identities = 36/138 (26%), Positives = 53/138 (38%), Gaps = 22/138 (15%)

Query: 23   GNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTPAQST 82
            G  P  ++ E      +   S  P+   +E+P   R AR  P + PT S+  P  PA  T
Sbjct: 2755 GQGPFSNSSEKVFVRGTQDSSAVPSAAHQEAPVTSRPARARPPDSPT-SLAPPLAPAAPT 2813

Query: 83   RESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNP-RRARGSP 141
              S                   + SP + PT  ++    + L+     P+ P RR RG  
Sbjct: 2814 PPS------------------VTVSPSSPPTPPSQAL--SSLKAVGPPPQTPPRRHRGLQ 2853

Query: 142  GNRPAQSTREPRKPTNAE 159
              RPA+ T      T +E
Sbjct: 2854 AARPAEPTLPSTHVTPSE 2871



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 43/173 (24%), Positives = 59/173 (34%), Gaps = 29/173 (16%)

Query: 7    RARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGN 66
            R +ESP     +   P +    S  +P TP             A  S   P  A + P  
Sbjct: 2160 RLQESPSLSALSEAQPSSPARPSAPKPSTPKS-----------AEPSATTPSDAPQPPAP 2208

Query: 67   QPTQSMR-EPR-TPAQSTRESWKPTHAEQARAPET---------DQRGASESPGNRPTQS 115
            QP Q    EPR  P ++++ +  P   +    P T            G ++ P   P   
Sbjct: 2209 QPAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTPYAQIIQSLQLSGHAQGPSQGPAAP 2268

Query: 116  TRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDP 168
              E +      AR +   P    G+P  R   S   P  P  AE AR P   P
Sbjct: 2269 PSEPKPHAAVFARVASPPP----GAPEKR-VPSAGGP--PVLAEKARVPTVPP 2314



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 24/88 (27%), Positives = 33/88 (37%), Gaps = 9/88 (10%)

Query: 88  PTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQ 147
           P    +   P+   + ASE+P        R +Q    + A   P +PR  + SP   PAQ
Sbjct: 275 PQSGLRREEPDLQPQLASEAP-------RRPAQPPPSKSALLPPPSPRVGKRSPPGPPAQ 327

Query: 148 STREPRKP--TNAEHARAPETDPHEARG 173
               P  P     E     +T   E RG
Sbjct: 328 PAATPTSPHRRTQEPVLPEDTTTEEKRG 355



 Score = 29.3 bits (64), Expect = 2.5
 Identities = 32/153 (20%), Positives = 51/153 (33%), Gaps = 31/153 (20%)

Query: 12  PGNP----RRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPR----RARES 63
           PG P    R +        + +  +P +P+ + +          + PG PR      R  
Sbjct: 530 PGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPG--------DEPGRPRSRGPAGRTE 581

Query: 64  PGNQPTQSMRE----PRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTR-- 117
           PG  P Q +R     P T +++ +E   P     A  PE   +         P Q+ R  
Sbjct: 582 PGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEARTKAPPGRKREPPAQAVRFL 641

Query: 118 ---------ESQETDLRRARQSPRNPRRARGSP 141
                     +    L + R  P   +R R  P
Sbjct: 642 PWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGP 674


>gi|6857826 RNA-binding protein S1, serine-rich domain [Homo
           sapiens]
          Length = 305

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 30/145 (20%), Positives = 54/145 (37%), Gaps = 1/145 (0%)

Query: 24  NQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTPAQSTR 83
           N    STR P    +  R   K   R+++       + +  G   T+  R   + + STR
Sbjct: 17  NNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTR 76

Query: 84  ESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARGSPGN 143
                T +  +        G+S S  +  + S+  S+ +    +  SP +P R R     
Sbjct: 77  SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP-SPSRRRHDNRR 135

Query: 144 RPAQSTREPRKPTNAEHARAPETDP 168
           R    ++ P++       R+P   P
Sbjct: 136 RSRSKSKPPKRDEKERKRRSPSPKP 160


>gi|18379334 RNA-binding protein S1, serine-rich domain [Homo
           sapiens]
          Length = 305

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 30/145 (20%), Positives = 54/145 (37%), Gaps = 1/145 (0%)

Query: 24  NQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMREPRTPAQSTR 83
           N    STR P    +  R   K   R+++       + +  G   T+  R   + + STR
Sbjct: 17  NNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTR 76

Query: 84  ESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARGSPGN 143
                T +  +        G+S S  +  + S+  S+ +    +  SP +P R R     
Sbjct: 77  SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSP-SPSRRRHDNRR 135

Query: 144 RPAQSTREPRKPTNAEHARAPETDP 168
           R    ++ P++       R+P   P
Sbjct: 136 RSRSKSKPPKRDEKERKRRSPSPKP 160


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/183 (20%), Positives = 72/183 (39%), Gaps = 27/183 (14%)

Query: 11  SPGNPRRARESPGNQPTQSTRE-----PRTPAQSTRESWKPTHRARESPGNPRRARESPG 65
           +P  P+    +   +P  +T +     P+ PA +T +   PT     +P  P+    +  
Sbjct: 271 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP 330

Query: 66  NQPTQSMRE-------------PRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRP 112
            +P  + +E             P+ PA +T +   PT  ++  AP T +  +  +P   P
Sbjct: 331 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP-APTTTKEPSPTTP-KEP 388

Query: 113 TQSTRESQETDLRR-----ARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETD 167
             +T +S  T  +       + +P  P+    +    PA +T  P++P      +   T 
Sbjct: 389 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEPAPTTPKKPAPTT 446

Query: 168 PHE 170
           P E
Sbjct: 447 PKE 449



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 41/179 (22%), Positives = 68/179 (37%), Gaps = 27/179 (15%)

Query: 11  SPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQ 70
           +P  P++   +   +P  +T  P+ PA +T +   PT     +P  P+    +   + T 
Sbjct: 435 APTTPKKPAPTTPKEPAPTT--PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 492

Query: 71  SMRE------PRTPAQSTRESWKPTHAEQ---------------ARAPETDQRGASESPG 109
           +  E      P  PA +T E   PT  E+               A AP T +  A  +P 
Sbjct: 493 TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 552

Query: 110 NRPTQSTRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDP 168
                + +E   T  +    +P  P+    +    PA +T  P+KP   E A     +P
Sbjct: 553 EPAPTTPKEPAPTTPKET--APTTPKGTAPTTLKEPAPTT--PKKPAPKELAPTTTKEP 607



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 36/158 (22%), Positives = 60/158 (37%), Gaps = 12/158 (7%)

Query: 11  SPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQ 70
           +P  P+ A  +   +P  +T  P+ PA +T +   PT     +P  P+    +   +P  
Sbjct: 531 APTTPKAAAPNTPKEPAPTT--PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA- 587

Query: 71  SMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQS 130
               P TP +   +   PT  ++  +   D+   +   G  PT     +  T    A   
Sbjct: 588 ----PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA--- 640

Query: 131 PRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDP 168
           P  P+    +    PA +T  P+KP   E A      P
Sbjct: 641 PTTPKGTAPTTLKEPAPTT--PKKPAPKELAPTTTKGP 676



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 39/151 (25%), Positives = 63/151 (41%), Gaps = 13/151 (8%)

Query: 26  PTQSTREPRTP-AQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMRE-----PRTPA 79
           PT       TP A++T +    T     +P  P+    +   +PT +  +     P+ PA
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248

Query: 80  QSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNPRRARG 139
            +T +S   T  E A  P T +  A  +P      +T+E   T  + A  +P+ P  A  
Sbjct: 249 PTTTKSAPTTPKEPA--PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APT 304

Query: 140 SPGNRPAQSTREPRKPTNAEHARAPETDPHE 170
           +P  +PA +T  P++P          T P E
Sbjct: 305 TP-KKPAPTT--PKEPAPTTPKEPTPTTPKE 332



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 41/184 (22%), Positives = 72/184 (39%), Gaps = 18/184 (9%)

Query: 11  SPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRR----------- 59
           +P  P+    +   +P  +T  P+ PA +T +   PT     SP  P+            
Sbjct: 341 APTTPKEPAPTAPKKPAPTT--PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 398

Query: 60  ARESPGNQPTQSM-REPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRE 118
             + P    T+S    P+ P+ +T +   PT  ++  AP T ++ A  +P      + +E
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP-APTTPKKPAPTTPKEPAPTTPKE 457

Query: 119 SQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARAPETDPHEARGSHRFI 178
              T  +  + +P  P+    +     A +T +   PT  E   AP T    A  +   +
Sbjct: 458 PAPTTTK--KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTPEEL 514

Query: 179 PRTT 182
             TT
Sbjct: 515 APTT 518



 Score = 35.0 bits (79), Expect = 0.046
 Identities = 33/148 (22%), Positives = 61/148 (41%), Gaps = 24/148 (16%)

Query: 15  PRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRR-ARESPGNQPTQSMR 73
           P+    +   +PT +T +   PA +T +   PT     +P  P+  A  +P      +++
Sbjct: 596 PKELAPTTTKEPTSTTCDK--PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK 653

Query: 74  EPR--TPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSP 131
           EP   TP +   +   P          T  +G + +  ++P  +T   +ET       +P
Sbjct: 654 EPAPTTPKKPAPKELAP----------TTTKGPTSTTSDKPAPTT--PKET-------AP 694

Query: 132 RNPRRARGSPGNRPAQSTREPRKPTNAE 159
             P+    +   +PA +T E   PT +E
Sbjct: 695 TTPKEPAPTTPKKPAPTTPETPPPTTSE 722



 Score = 33.5 bits (75), Expect = 0.13
 Identities = 36/154 (23%), Positives = 57/154 (37%), Gaps = 24/154 (15%)

Query: 15  PRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARESPGNQPTQSMRE 74
           P+    +    PT +T +   PA +T +   PT     +P  P++        PT     
Sbjct: 665 PKELAPTTTKGPTSTTSDK--PAPTTPKETAPTTPKEPAPTTPKKP------APT----T 712

Query: 75  PRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQETDLRRARQSPRNP 134
           P TP  +T E   PT  ++   P T  +   ES      + T ++ E        SP+ P
Sbjct: 713 PETPPPTTSEVSTPTTTKE---PTTIHKSPDESTPELSAEPTPKALE-------NSPKEP 762

Query: 135 --RRARGSPGNRPAQSTREPRKPTNAEHARAPET 166
                +     +P  +T    K T  +    PET
Sbjct: 763 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 796



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 38/193 (19%), Positives = 70/193 (36%), Gaps = 19/193 (9%)

Query: 4   EEHRARESPGNPRRARESPGNQPTQSTREPRTPAQSTRESWKPTHRARESPGNPRRARES 63
           +++R ++ P       +  G+       +  TP  ST +  K +   + +   P   R S
Sbjct: 70  KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 129

Query: 64  -PGNQPTQSMREPRTPAQSTRESWKPTHAEQARAPETDQRGASESPGNRPTQSTRESQET 122
            P N  T          ++T E+ + T   +    +T   G  ++   + TQS  ++   
Sbjct: 130 LPPNSDTSKETSLTVNKETTVETKETTTTNK----QTSTDGKEKTTSAKETQSIEKTSAK 185

Query: 123 DLRR-----ARQSPRNPRRARGSPGNRPAQST---------REPRKPTNAEHARAPETDP 168
           DL       A+ +P+     +G     P + T           P++PT      AP T  
Sbjct: 186 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 245

Query: 169 HEARGSHRFIPRT 181
             A  + +  P T
Sbjct: 246 EPAPTTTKSAPTT 258



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 37/175 (21%), Positives = 66/175 (37%), Gaps = 23/175 (13%)

Query: 15  PRRARESPGNQPTQSTREPRTPAQSTRESWKP----THRARESPGNPRRARESPGNQPTQ 70
           P  + E        S +EP  P   T  + KP    T + + +  + R   E+    P  
Sbjct: 744 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 803

Query: 71  SMREPRTPAQSTRESWKPTHAEQARAPETDQ---------RGASESPGNRPTQSTRESQE 121
           + +E  T  + T ES       Q  +  T           +  + +P    T+ T  + E
Sbjct: 804 T-KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 862

Query: 122 TDLRRARQSPRNPRRARGSPGN--RPAQSTREPRKPTNAE------HARAPETDP 168
             + +  ++ +   RA  S     +P + T+ P+KPT+ +        R P+T P
Sbjct: 863 I-MNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 916


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.122    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,973,023
Number of Sequences: 37866
Number of extensions: 627290
Number of successful extensions: 6772
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 198
Number of HSP's successfully gapped in prelim test: 937
Number of HSP's that attempted gapping in prelim test: 4141
Number of HSP's gapped (non-prelim): 2632
length of query: 210
length of database: 18,247,518
effective HSP length: 98
effective length of query: 112
effective length of database: 14,536,650
effective search space: 1628104800
effective search space used: 1628104800
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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