Guide to the Human Genome
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Search of human proteins with 239753329

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo
sapiens]
         (351 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo ...   701   0.0  
gi|239741651 PREDICTED: hypothetical protein XP_002342270 [Homo ...   336   2e-92
gi|239758117 PREDICTED: hypothetical protein [Homo sapiens]           305   5e-83
gi|239754599 PREDICTED: hypothetical protein [Homo sapiens]           294   9e-80
gi|239758008 PREDICTED: hypothetical protein XP_002346266 [Homo ...   273   2e-73
gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]           257   1e-68
gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo ...   254   8e-68
gi|239752579 PREDICTED: hypothetical protein XP_002348295 [Homo ...   245   4e-65
gi|239752632 PREDICTED: hypothetical protein XP_002347697 [Homo ...   226   2e-59
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]           127   1e-29
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     57   2e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        57   3e-08
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             56   6e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            55   9e-08
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         54   2e-07
gi|239755739 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo ...    52   1e-06
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          51   1e-06
gi|24475863 H1 histone family, member O, oocyte-specific [Homo s...    51   2e-06
gi|239754674 PREDICTED: hypothetical protein [Homo sapiens]            50   3e-06
gi|239750250 PREDICTED: hypothetical protein [Homo sapiens]            50   3e-06
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           50   3e-06
gi|239753399 PREDICTED: hypothetical protein [Homo sapiens]            49   9e-06
gi|239741865 PREDICTED: hypothetical protein XP_002342328 [Homo ...    49   9e-06
gi|4885381 histone cluster 1, H1b [Homo sapiens]                       49   9e-06
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]     49   9e-06
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]     49   9e-06
gi|239754474 PREDICTED: similar to mucin [Homo sapiens]                48   1e-05
gi|169172209 PREDICTED: hypothetical protein [Homo sapiens]            48   1e-05

>gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo
           sapiens]
          Length = 351

 Score =  701 bits (1810), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MRGLDQMEIRGGPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATL 60
           MRGLDQMEIRGGPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATL
Sbjct: 1   MRGLDQMEIRGGPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATL 60

Query: 61  RSHPITPAPALLLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPY 120
           RSHPITPAPALLLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPY
Sbjct: 61  RSHPITPAPALLLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPY 120

Query: 121 QDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPR 180
           QDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPR
Sbjct: 121 QDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPR 180

Query: 181 RRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQ 240
           RRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQ
Sbjct: 181 RRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQ 240

Query: 241 KAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKA 300
           KAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKA
Sbjct: 241 KAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKA 300

Query: 301 EAGQGQNRRNEVGGQHNLALLECDVIGKVQPKTKKDVSWLDSVQLRTQMLS 351
           EAGQGQNRRNEVGGQHNLALLECDVIGKVQPKTKKDVSWLDSVQLRTQMLS
Sbjct: 301 EAGQGQNRRNEVGGQHNLALLECDVIGKVQPKTKKDVSWLDSVQLRTQMLS 351


>gi|239741651 PREDICTED: hypothetical protein XP_002342270 [Homo
           sapiens]
          Length = 337

 Score =  336 bits (862), Expect = 2e-92
 Identities = 205/351 (58%), Positives = 228/351 (64%), Gaps = 54/351 (15%)

Query: 1   MRGLDQMEIRGGPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATL 60
           MRGLDQM IR GPYLLLGE +GHSALGAQP QAA GDADELLELPALLQRPAGRGPCA+L
Sbjct: 1   MRGLDQMAIREGPYLLLGEVLGHSALGAQPAQAANGDADELLELPALLQRPAGRGPCASL 60

Query: 61  RSHPITPAPALLLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPY 120
           R   +TPA ALLLLSH   AQRRSM+A  A+  SPGR RLGKEP  RESWTRSAP RC  
Sbjct: 61  RDSRVTPATALLLLSHCSRAQRRSMRAAAAQERSPGRRRLGKEPLIRESWTRSAPWRCLS 120

Query: 121 QDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPR 180
           QDA RAGS+VC S PQ                  +RGGGGKK + QKA   GAK  +KP+
Sbjct: 121 QDAGRAGSQVCGSSPQ------------------TRGGGGKKLQRQKATVMGAKSRKKPQ 162

Query: 181 RRGERAAAAGGKKLQKAAAAKSRGGGGKKTA----AAGGKKPRRRRGQKAAKSRGGGDKK 236
             G++AA AG         AKS GGGGKK      AA G+K R      AAKSRGGG KK
Sbjct: 163 HWGQKAATAG---------AKSPGGGGKKPGQEKPAATGEKTR------AAKSRGGGGKK 207

Query: 237 LERQKAALTGVKS------RGDKKPLRGGKKQRERGQNT-----KSRGGGGEKPQKAAAA 285
             R+K A  G K+       G K    GG+K R RGQ       KSRGGGG KPQK AAA
Sbjct: 208 PRREKPAAAGAKNPQKAAAAGAKFREAGGRKPRWRGQKATEAGAKSRGGGGIKPQKPAAA 267

Query: 286 GAKSRGGRGEKPQKAEAGQGQNRRNEVGGQHNLALLECDVIGKVQPKTKKD 336
           GAK  GG+  KP++    +GQ+  N V GQ++LA LECDV GKVQ KT KD
Sbjct: 268 GAKIHGGK--KPRR----RGQSSGNGVEGQNSLAFLECDVEGKVQRKTNKD 312



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 56/148 (37%), Positives = 70/148 (47%), Gaps = 20/148 (13%)

Query: 79  PAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNR 138
           P Q +          +  RG  GK+PRR +     A      Q A+ AG++        R
Sbjct: 183 PGQEKPAATGEKTRAAKSRGGGGKKPRREKPAAAGAKNP---QKAAAAGAKF-------R 232

Query: 139 GGGDKKPRRRGQKA----AKSRGGGGKKPRGQKAAGAGAKKH--RKPRRRGERAAAAGGK 192
             G +KPR RGQKA    AKSRGGGG KP  QK A AGAK H  +KPRRRG+  ++  G 
Sbjct: 233 EAGGRKPRWRGQKATEAGAKSRGGGGIKP--QKPAAAGAKIHGGKKPRRRGQ--SSGNGV 288

Query: 193 KLQKAAAAKSRGGGGKKTAAAGGKKPRR 220
           + Q + A       GK         PRR
Sbjct: 289 EGQNSLAFLECDVEGKVQRKTNKDNPRR 316


>gi|239758117 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 465

 Score =  305 bits (780), Expect = 5e-83
 Identities = 204/374 (54%), Positives = 224/374 (59%), Gaps = 75/374 (20%)

Query: 12  GPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATLRSHPITPAPAL 71
           GPYLLLGE +GHSALGAQ  Q A GDADELLELPALLQ P G  PCA+LR   +TPA AL
Sbjct: 19  GPYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHPTGCDPCASLRDSRVTPATAL 78

Query: 72  LLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVC 131
           LLLSH   AQRRS+QA  A+  S GRG LGKEP  +ESWTRS PRRC  QDA R+GSRVC
Sbjct: 79  LLLSHRGRAQRRSIQAAAAQEQSTGRGCLGKEPPSQESWTRSDPRRCLSQDAVRSGSRVC 138

Query: 132 RSRPQNRGGGDKKPRRRGQKA----AKSRGGGGKKP--RGQKAAGAGAKKHRKPRRRGER 185
           RSRPQ RGGG K+PRR  QKA    AKSRGG GKKP  RGQKAA AGAK       RG  
Sbjct: 139 RSRPQTRGGGGKQPRR--QKAAVAGAKSRGGEGKKPQRRGQKAATAGAKS------RGGG 190

Query: 186 AAAAGGKKL---QKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKA 242
             + GGKK+   QK AA   R GGGK+          RRRGQKA+KS  GG +    QKA
Sbjct: 191 VRSLGGKKMRRGQKGAAGAKRCGGGKQP---------RRRGQKASKS--GGVRCQTPQKA 239

Query: 243 ALTGVKSR---------------------------------GDKKPLRGGKKQRERGQNT 269
           A  GVKSR                                 GDKKPLR  K  R RGQ  
Sbjct: 240 AAQGVKSRKKLRQRGQKAAAAGQEAAAGKTCGGGGEKHRGGGDKKPLR--KNSRWRGQ-- 295

Query: 270 KSRGGGGEKPQKAAAAGAKSRG---------GRGEKPQKAEAGQGQNRRNEVGGQHNLAL 320
           K+   GG+KPQKAAAAG + R           R + P+K    +GQN  N V GQ +LA 
Sbjct: 296 KAAAAGGKKPQKAAAAGGERRKKLRRQKAAVARAKSPKKPR-WRGQNSGNGVEGQRSLAF 354

Query: 321 LECDVIGKVQPKTK 334
           LE DV GKVQ KTK
Sbjct: 355 LEFDVEGKVQRKTK 368


>gi|239754599 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 294

 Score =  294 bits (752), Expect = 9e-80
 Identities = 170/267 (63%), Positives = 182/267 (68%), Gaps = 25/267 (9%)

Query: 1   MRGLDQMEIRGGPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATL 60
           MRG DQMEIRGGPYLLLGE VGHSALGAQP QAA GDADELLEL ALLQ  AGRGPCATL
Sbjct: 1   MRGPDQMEIRGGPYLLLGEVVGHSALGAQPAQAANGDADELLELSALLQPRAGRGPCATL 60

Query: 61  RSHPITPAPALLLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPY 120
               ITPA ALLLLSH L AQ R MQAT A+AGSPG GRLGKEP  RESWT SAPRRCP 
Sbjct: 61  SGRCITPATALLLLSHRLRAQCRPMQATAAEAGSPGLGRLGKEPPSRESWTGSAPRRCPC 120

Query: 121 QDASRAGSRVCRSRPQNRGGGDKKPRRRGQKA--AKSRGGGGKKPRGQKAAGAGAKK--- 175
           QDASRAGS VCRSRPQ+RGGG +KPRR+   A  AKS GGGGKKPR QK A AG K    
Sbjct: 121 QDASRAGSGVCRSRPQSRGGGSRKPRRQKAAAAQAKSLGGGGKKPRRQKCAAAGQKAAAE 180

Query: 176 ------HRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKS 229
                  +KPRR G++A  AG KK QKA             AAAG K PRRRR QKAAK+
Sbjct: 181 ESRRGGGKKPRRGGQKAVGAGAKKPQKA-------------AAAGTKTPRRRR-QKAAKA 226

Query: 230 RGGGDKKLERQKAALTGVKSRGDKKPL 256
              G K    +      + S    +P+
Sbjct: 227 AVWGQKAAAGESLTPNSLASVSFSRPM 253


>gi|239758008 PREDICTED: hypothetical protein XP_002346266 [Homo
           sapiens]
          Length = 316

 Score =  273 bits (698), Expect = 2e-73
 Identities = 166/311 (53%), Positives = 189/311 (60%), Gaps = 43/311 (13%)

Query: 13  PYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATLRSHPITPAPALL 72
           PYLLLGE +GHSALGAQP QAA GDADELLELPALLQ PAG  PCA+LR   +TPA ALL
Sbjct: 20  PYLLLGEVLGHSALGAQPAQAANGDADELLELPALLQLPAGCDPCASLRDSRVTPATALL 79

Query: 73  LLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCR 132
            LSH   AQRRSM A  A+  S GRG LGKEP  RESWTRS PR C  QDASR+GSRVCR
Sbjct: 80  PLSHRGRAQRRSMHAAAAQERSLGRGCLGKEPPNRESWTRSDPRHCISQDASRSGSRVCR 139

Query: 133 SRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGK 192
           SRPQ RGGG KKPRR+   AA ++  GGKKPR          + RKPRRRG+++ AAG K
Sbjct: 140 SRPQTRGGGGKKPRRQKDAAAGAKSRGGKKPR----------RGRKPRRRGQKSTAAGAK 189

Query: 193 ---------KLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSR--GGGDKKLERQK 241
                    + QK AAA ++ G G K +   G+K   R GQ+A      GGG KK   QK
Sbjct: 190 SRGEGGKKPRQQKPAAAGAKSGLGDKKSRRWGRKKPGRWGQEAVAGETCGGGGKK--PQK 247

Query: 242 AALTGVKSRGDKKPLR------------------GGKKQRERGQNTKSRGGGGEKPQKAA 283
           AA  G KS   KKP R                  GG+ Q+      KS G GG+K ++  
Sbjct: 248 AAAPGAKSH--KKPRRQWQKAAAEKVAVAGAESCGGRGQKAAAARAKSGGFGGKKQRRRG 305

Query: 284 AAGAKSRGGRG 294
               KSRGGRG
Sbjct: 306 QRAPKSRGGRG 316



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 67/173 (38%), Positives = 78/173 (45%), Gaps = 51/173 (29%)

Query: 176 HR-KPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKS----- 229
           HR + +RR   AAAA  + L +    K        T +     PR    Q A++S     
Sbjct: 83  HRGRAQRRSMHAAAAQERSLGRGCLGKEPPNRESWTRS----DPRHCISQDASRSGSRVC 138

Query: 230 ------RGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNT-----KSRGGGGEK 278
                 RGGG KK  RQK A  G KSRG KKP R G+K R RGQ +     KSRG GG+K
Sbjct: 139 RSRPQTRGGGGKKPRRQKDAAAGAKSRGGKKP-RRGRKPRRRGQKSTAAGAKSRGEGGKK 197

Query: 279 P--QKAAAAGAKSR---------------------------GGRGEKPQKAEA 302
           P  QK AAAGAKS                            GG G+KPQKA A
Sbjct: 198 PRQQKPAAAGAKSGLGDKKSRRWGRKKPGRWGQEAVAGETCGGGGKKPQKAAA 250



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 31/61 (50%), Positives = 37/61 (60%), Gaps = 13/61 (21%)

Query: 258 GGKKQRERGQNTKSRGGGGEKP--QKAAAAGAKSRGG----RGEKP----QKAEAGQGQN 307
           G +  R R Q   +RGGGG+KP  QK AAAGAKSRGG    RG KP    QK+ A   ++
Sbjct: 134 GSRVCRSRPQ---TRGGGGKKPRRQKDAAAGAKSRGGKKPRRGRKPRRRGQKSTAAGAKS 190

Query: 308 R 308
           R
Sbjct: 191 R 191


>gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 235

 Score =  257 bits (657), Expect = 1e-68
 Identities = 148/223 (66%), Positives = 161/223 (72%), Gaps = 28/223 (12%)

Query: 12  GPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATLRSHPITPAPAL 71
           GPYLLLGE VGHSALGAQP QAA    DE+LELPALLQRPAGR PCA+ R   ITPA AL
Sbjct: 16  GPYLLLGEVVGHSALGAQPAQAA----DEVLELPALLQRPAGRRPCASHRGRRITPATAL 71

Query: 72  LLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVC 131
           LLLSH   A+RRSMQA  AKAGSPGR R+GK P  RESWTRSAP+RCP QDA RAGSRVC
Sbjct: 72  LLLSHRGRAERRSMQAAAAKAGSPGRRRVGKGPPSRESWTRSAPQRCPSQDAGRAGSRVC 131

Query: 132 RSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGA-----KKHRKPRRRGERA 186
           RSRPQ+RGG     ++     AK RG GGK+PR QK A AGA     K H+KPRRRG++A
Sbjct: 132 RSRPQSRGG-----QKAAASGAKRRGVGGKEPRRQKPAAAGAKSRGGKSHKKPRRRGQKA 186

Query: 187 AAA-----GGKKLQKAAA--AKSRGGGGKKTAAAGGKKPRRRR 222
           A A     GG K QKAAA  AK+RGGG       GGKKPRR R
Sbjct: 187 APAKNSGGGGNKPQKAAAAGAKNRGGG-------GGKKPRRGR 222



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 63/196 (32%), Positives = 82/196 (41%), Gaps = 50/196 (25%)

Query: 160 GKKP----RGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGG 215
           G++P    RG++   A A      R R ER +        +AAAAK+ G  G++    G 
Sbjct: 53  GRRPCASHRGRRITPATALLLLSHRGRAERRS-------MQAAAAKA-GSPGRRRVGKG- 103

Query: 216 KKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGG 275
             P R    ++A  R         Q A   G +    +   RGG+K    G   K RG G
Sbjct: 104 -PPSRESWTRSAPQR------CPSQDAGRAGSRVCRSRPQSRGGQKAAASG--AKRRGVG 154

Query: 276 GEKP--QKAAAAGAKSRGGR---------------------GEKPQKAEAGQGQNRRNEV 312
           G++P  QK AAAGAKSRGG+                     G KPQKA A   +NR    
Sbjct: 155 GKEPRRQKPAAAGAKSRGGKSHKKPRRRGQKAAPAKNSGGGGNKPQKAAAAGAKNRGGGG 214

Query: 313 G-----GQHNLALLEC 323
           G     G+  L LL C
Sbjct: 215 GKKPRRGRRLLGLLPC 230


>gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo
           sapiens]
          Length = 321

 Score =  254 bits (649), Expect = 8e-68
 Identities = 169/314 (53%), Positives = 188/314 (59%), Gaps = 46/314 (14%)

Query: 12  GPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATLRSHPITPAPAL 71
           G YLLLGE +GHSALGAQ  Q A GDADELLELPALLQ  AG  PCA+LR   +TPA AL
Sbjct: 19  GLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAGCDPCASLRDSCVTPATAL 78

Query: 72  LLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVC 131
           LLLSH    QRRSMQA  A+  S GRG LGKEP + ES TRS PRRC  QDASR+GSRVC
Sbjct: 79  LLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVC 138

Query: 132 RSRPQNRGGGDKKP--------------------------RRRGQKA----AKSRGGGGK 161
           RSRPQ RGGG KKP                          RRRGQKA    AKS GGGGK
Sbjct: 139 RSRPQTRGGGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGK 198

Query: 162 KPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRR 221
           KP+  +A GA  +  +K RRRG++AAAAGG+K    A  K R  G K      G+K  RR
Sbjct: 199 KPQKARAVGARRRGWKKLRRRGKKAAAAGGEK----AGKKLRQQGEK------GRKKPRR 248

Query: 222 RGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQK 281
           RGQKAA + G   KK  RQKAA    KS   KKP R        G   +SR     + QK
Sbjct: 249 RGQKAAAAGGERCKKPRRQKAAAVSAKS--PKKPRRRVLNSARLG--AESRKNPQRRGQK 304

Query: 282 AAAAGAKSRGGRGE 295
           + A  AKSR G G+
Sbjct: 305 SMA--AKSRVGSGK 316



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 55/137 (40%), Positives = 68/137 (49%), Gaps = 21/137 (15%)

Query: 180 RRRGERAAAAGGKKLQKAAAAK-------SRGGGGKKTAAAGGKKPRRRRGQKAAKSRGG 232
           +RR  +AAAA  + L +    K       S   G ++  +    +   R  +   ++RGG
Sbjct: 88  QRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGG 147

Query: 233 GDKKLER-QKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRG 291
           G KK  R QKAA  G KSRG     RGGKK R RGQ             KAAAAGAKS G
Sbjct: 148 GGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQ-------------KAAAAGAKSCG 194

Query: 292 GRGEKPQKAEAGQGQNR 308
           G G+KPQKA A   + R
Sbjct: 195 GGGKKPQKARAVGARRR 211



 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 66/180 (36%), Positives = 87/180 (48%), Gaps = 38/180 (21%)

Query: 146 RRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGG 205
           RR  Q AA      G+   G++     +     PRR   + A+  G ++ ++   ++RGG
Sbjct: 89  RRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRP-QTRGG 147

Query: 206 GGKKTAAAGGKKPRRRRGQKAA----KSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKK 261
           GGKK           RRGQKAA    KSRGG             GV+SRG KK  R G+K
Sbjct: 148 GGKKP----------RRGQKAATAGAKSRGG-------------GVRSRGGKKIRRRGQK 184

Query: 262 QRERGQNTKSRGGGGEKPQKAAAAGAKSRG-----GRGEKPQKA---EAGQGQNRRNEVG 313
               G   KS GGGG+KPQKA A GA+ RG      RG+K   A   +AG+   ++ E G
Sbjct: 185 AAAAG--AKSCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKG 242


>gi|239752579 PREDICTED: hypothetical protein XP_002348295 [Homo
           sapiens]
          Length = 240

 Score =  245 bits (626), Expect = 4e-65
 Identities = 155/253 (61%), Positives = 165/253 (65%), Gaps = 35/253 (13%)

Query: 12  GPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATLRSHPITPAPAL 71
           GPYLLLGE +GHSALGAQP QAA GDADELLELPALLQ PAG  PCA+LR   +TPA AL
Sbjct: 19  GPYLLLGEVLGHSALGAQPAQAANGDADELLELPALLQLPAGCDPCASLRDSRVTPATAL 78

Query: 72  LLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVC 131
           L LSH   AQRRSM A  A+  S GRG LGKEP  RESWTRS PR C  QDASR+GSRVC
Sbjct: 79  LPLSHRGRAQRRSMHAAAAQERSLGRGCLGKEPPNRESWTRSDPRHCISQDASRSGSRVC 138

Query: 132 RSRPQNRGGGDKKPRRRGQKAA--KSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAA 189
           RSRPQ RG G KK R+RG+KAA  K+  G  KKP  QKAA  GAK       RG R    
Sbjct: 139 RSRPQTRGSGGKKLRQRGEKAAAVKTCSGRSKKPGRQKAAVMGAKS------RGGR---- 188

Query: 190 GGKKLQKAAA--AKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGV 247
            GKK QKAAA  AKS  GGGKK     GKKP RR                  QKAA+TG 
Sbjct: 189 -GKKPQKAAAAGAKSCNGGGKK-LGRWGKKPGRR-----------------GQKAAVTGA 229

Query: 248 KSRGDKKPLRGGK 260
           KSR  KKP R G+
Sbjct: 230 KSR--KKPQRRGQ 240



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 44/118 (37%), Positives = 58/118 (49%), Gaps = 16/118 (13%)

Query: 192 KKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRG--GGDKKLERQKAALTGVKS 249
           ++   AAAA+ R  G        GK+P  R     +  R     D      +   +  ++
Sbjct: 89  RRSMHAAAAQERSLG----RGCLGKEPPNRESWTRSDPRHCISQDASRSGSRVCRSRPQT 144

Query: 250 RGDKKPLRGGKKQRERGQNT---KSRGGGGEKP--QKAAAAGAKSRGGRGEKPQKAEA 302
           RG      GGKK R+RG+     K+  G  +KP  QKAA  GAKSRGGRG+KPQKA A
Sbjct: 145 RGS-----GGKKLRQRGEKAAAVKTCSGRSKKPGRQKAAVMGAKSRGGRGKKPQKAAA 197


>gi|239752632 PREDICTED: hypothetical protein XP_002347697 [Homo
           sapiens]
          Length = 231

 Score =  226 bits (576), Expect = 2e-59
 Identities = 141/224 (62%), Positives = 150/224 (66%), Gaps = 30/224 (13%)

Query: 12  GPYLLLGEAVGHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATLRSHPITPAPAL 71
           G YLLLGE +GHSALGAQ  Q A GDADELLELPALLQ  AG  PCA+LR   +TPA AL
Sbjct: 19  GLYLLLGEVLGHSALGAQHAQPANGDADELLELPALLQHLAGCDPCASLRDSCVTPATAL 78

Query: 72  LLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVC 131
           LLLSH    QRRSMQA  A+  S GRG LGKEP + ES TRS PRRC  QDASR+GSRVC
Sbjct: 79  LLLSHRGQVQRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVC 138

Query: 132 RSRPQNRGGGDKKPRRRGQKA----AKSRGG-----GGKK--PRGQKAAGAGAKKHRKPR 180
           RSRPQ RGGG KKP RRGQKA    AKSRGG     GGKK   RGQKAA AGAK      
Sbjct: 139 RSRPQTRGGGGKKP-RRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAK------ 191

Query: 181 RRGERAAAAGGKKLQKAAAAKSRGGG-------GKKTAAAGGKK 217
                +   GGKK QKA A  +R  G       GKK AAAGG+K
Sbjct: 192 -----SCGGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEK 230



 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 56/142 (39%), Positives = 73/142 (51%), Gaps = 15/142 (10%)

Query: 180 RRRGERAAAAGGKKLQKAAAAK-------SRGGGGKKTAAAGGKKPRRRRGQKAAKSRGG 232
           +RR  +AAAA  + L +    K       S   G ++  +    +   R  +   ++RGG
Sbjct: 88  QRRSMQAAAAQEQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSRPQTRGG 147

Query: 233 GDKKLER-QKAALTGVKSRGDKKPLRGGKKQRERGQNT-----KSRGGGGEKPQKAAAAG 286
           G KK  R QKAA  G KSRG     RGGKK R RGQ       KS GGGG+KPQKA A G
Sbjct: 148 GGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAVG 207

Query: 287 AKSRGGR--GEKPQKAEAGQGQ 306
           A+ RG +    + +KA A  G+
Sbjct: 208 ARRRGWKKLRRRGKKAAAAGGE 229


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score =  127 bits (320), Expect = 1e-29
 Identities = 107/264 (40%), Positives = 136/264 (51%), Gaps = 52/264 (19%)

Query: 83  RSMQATVAKAGSPGRG-RLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGG 141
           R  +A+ A A S G G + G    +R    R  PR   +Q+  R   +   ++P  RGGG
Sbjct: 369 RRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPR---WQNPRRRAQKAPAAKP--RGGG 423

Query: 142 DKKPRRRGQKAAKSRG-----GGGKKPR------GQKAAGAGAKKHRKPRRRGERAAAAG 190
            KKPRRRG KAAKSRG     GGGKKPR       QKAA AGA+     ++  ++A+AAG
Sbjct: 424 SKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAG 483

Query: 191 ------------GKKLQKAAAAKSRGGGGKKTAAA----GGKKPRRRRGQKA-AKSRGGG 233
                       GK L +    K+   G K TAA     G K+PRR++   A AKSR GG
Sbjct: 484 TKSRGGGLKSHSGKNLWR-RGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGG 542

Query: 234 DKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQK--AAAAGAKSRG 291
            K  +RQKA   G  S G      GG KQ        SRGGGG KP++    AA AK+RG
Sbjct: 543 SKSRQRQKAVAAGATSHGG-----GGNKQ--------SRGGGGNKPRQWGQTAAAAKTRG 589

Query: 292 GRGEKP--QKAEAGQGQNRRNEVG 313
           G  ++P  QKA AG  ++R  + G
Sbjct: 590 GGDKQPGWQKAAAGVTKSRSGDGG 613



 Score =  124 bits (312), Expect = 1e-28
 Identities = 115/309 (37%), Positives = 146/309 (47%), Gaps = 80/309 (25%)

Query: 90  AKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRG 149
           A AG+   G  G++PRRR             Q A+  GS+  R R Q       K R  G
Sbjct: 109 AAAGTKSLGGRGRKPRRRG------------QKAAATGSKKPRWRAQKSAAAGSKNRGAG 156

Query: 150 -QKAAKSRG---GGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAA----AK 201
            QKAA + G    GG+KP+   AAGA ++  +KPRRRG ++     KK ++  A     K
Sbjct: 157 AQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGK 216

Query: 202 SRGG------------GGKKTAAAGGKKPR--RRRGQKAA--------KSRGGGDKKLER 239
           +RGG            GG K+   GGKKP+  RRRGQKAA        KSRGGGDKKL R
Sbjct: 217 TRGGRRKKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRR 276

Query: 240 Q--KAALTGVKSRG----DKKPL--------------------RGGKKQRERGQN-TKS- 271
           Q   AAL G K RG     +KP                     RGGKK R RGQ  TK+ 
Sbjct: 277 QGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAA 336

Query: 272 -----RGGGGEKPQKAAAAGAKSRGG---RGEKPQKAEAGQGQNRRNEVGGQHNLALLEC 323
                RGGGG+  QKAA  G KSR     RG+KP++ +A     +    G +  L   + 
Sbjct: 337 AAGTKRGGGGQ--QKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKR 394

Query: 324 DVIGKVQPK 332
              G+ +P+
Sbjct: 395 RGDGRKKPR 403



 Score =  121 bits (303), Expect = 1e-27
 Identities = 109/295 (36%), Positives = 139/295 (47%), Gaps = 87/295 (29%)

Query: 92  AGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQK 151
           A +  + R GK+PRRR + +R         +  +   R  +SR     GG +K  RR + 
Sbjct: 178 AAAGAKSRSGKKPRRRGAKSRG-------DEDKKGRQREAKSRFGKTRGGRRKKHRRPKP 230

Query: 152 AA---KSRGGGGKKP-----RGQKAAGAGAKK--------HRKPRRRGERAAAAGGKKLQ 195
           AA   KSR GGGKKP     RGQKAA  G  +         +K RR+G+ AA AG K+  
Sbjct: 231 AAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRG 290

Query: 196 KAAA-----AKSRGGGGKKTAAA-------GGKKPRRRRGQKAAKS------RGGG---- 233
            A A     AK RGG G K+          GGKKPRRR GQKA K+      RGGG    
Sbjct: 291 AATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRR-GQKATKAAAAGTKRGGGGQQK 349

Query: 234 ---------------DKKLERQKAALTGVKSR--GDKKPL-----RGGKKQRERGQN--- 268
                           KK  RQKA+  G KSR  GDKK L     RG  +++ R QN   
Sbjct: 350 AAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRR 409

Query: 269 -------TKSRGGGGEKPQKAAAAGAKSRGGR-----GEKPQKAEAGQGQNRRNE 311
                   K RGGG +KP++     AKSRGG+     G+KP++    +GQ  R +
Sbjct: 410 RAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRR----RGQKARQK 460



 Score =  119 bits (297), Expect = 5e-27
 Identities = 95/245 (38%), Positives = 126/245 (51%), Gaps = 43/245 (17%)

Query: 113 SAPRRCPYQDASRAGSRVCRS-----RPQNRGGGDKKPRRRGQKAA-----------KSR 156
           +A    P   A+ AG ++  S     R Q    G KK R RGQK A           K+ 
Sbjct: 34  AAESAAPALSAAAAGVKILGSGDKKLRRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAA 93

Query: 157 GGGGKKPRG---QKAAGAGAK----KHRKPRRRGERAAAAGGKK----LQKAAAA--KSR 203
           G GG + RG   QKAA AG K    + RKPRRRG++AAA G KK     QK+AAA  K+R
Sbjct: 94  GAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNR 153

Query: 204 GGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQR 263
           G G +K AAA G K +   G+K  K+   G K    +K    G KSRGD+   + G+++ 
Sbjct: 154 GAGAQKAAAAAGVKSQG--GEKPQKAAAAGAKSRSGKKPRRRGAKSRGDED--KKGRQRE 209

Query: 264 ERGQNTKSRGGGGEKPQ--KAAAAGAKSRGGRGEKPQK--------AEAGQGQNRRNEVG 313
            + +  K+RGG  +K +  K AA GAKSR G G+KPQK        A  G+ +  ++  G
Sbjct: 210 AKSRFGKTRGGRRKKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGG 269

Query: 314 GQHNL 318
           G   L
Sbjct: 270 GDKKL 274



 Score =  117 bits (293), Expect = 2e-26
 Identities = 115/310 (37%), Positives = 136/310 (43%), Gaps = 91/310 (29%)

Query: 81  QRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRP--QNR 138
           QRR  Q    KA + G+ R+GK     +   R   +      A R G+     +P  + R
Sbjct: 248 QRRRGQ----KAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGR 303

Query: 139 GG---------------GDKKPRRRGQKAAKSRGGGGKKPRG--QKAAGAGAKKHRKPRR 181
           GG               G KKPRRRGQKA K+   G K+  G  QKAA  G K  +K RR
Sbjct: 304 GGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRR 363

Query: 182 RGERAAAAGGKKLQKAAAAKSRGGGGKK------TAAAGGKKPR----RRRGQKA--AKS 229
           RG++      ++   AA AKSRGGG KK          G KKPR    RRR QKA  AK 
Sbjct: 364 RGKKPR----RQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKP 419

Query: 230 RGGGDKKLERQ--KAALTGVKSRGDKKPLRGGKKQRERGQN------------------- 268
           RGGG KK  R+  KAA    KSRG K    GGKK R RGQ                    
Sbjct: 420 RGGGSKKPRRRGPKAA----KSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQG 475

Query: 269 --------TKSRGGG---------GEKPQKAA-------AAGAKSRGGRGEKPQKAEAGQ 304
                   TKSRGGG           + QKA        AAGAKSRG +  + QK     
Sbjct: 476 RQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAG 535

Query: 305 GQNRRNEVGG 314
            ++R   VGG
Sbjct: 536 AKSR---VGG 542



 Score =  113 bits (283), Expect = 2e-25
 Identities = 125/322 (38%), Positives = 138/322 (42%), Gaps = 110/322 (34%)

Query: 82  RRSMQATVA-----KAGSPGRGRLGKEPRRRESWTRSAPRRC------PYQDASRAG--S 128
           RR  +A  A      AG+  RGR  K+PRR++     A  R         Q A  AG  S
Sbjct: 501 RRGQKAEAAGEKATAAGAKSRGR--KQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATS 558

Query: 129 RVCRSRPQNRGGGDKKPRRRGQKAA--KSRGGG---------------------GKKPRG 165
                  Q+RGGG  KPR+ GQ AA  K+RGGG                     GKK   
Sbjct: 559 HGGGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWR 618

Query: 166 QKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGK-----KTAAAGG----- 215
           QKAAG GAK  +KP RRG++ AAA  K    A  A SRG GGK     K AAAG      
Sbjct: 619 QKAAGTGAKSRKKPWRRGQKDAAAAEKAW--ATGATSRGSGGKQPRWQKPAAAGSESSAA 676

Query: 216 ----------KKPRRRR-------GQKAA----------------KSRGGGDKKLERQKA 242
                     KKPRRRR       GQ AA                KSRGGG  K      
Sbjct: 677 AAVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGG 736

Query: 243 ALT----GVKSRGDKKPLR-----GGKKQRERGQNTKSRGG------GGEKPQKAAAAG- 286
           A +    G KSR  KK        GG  +R RG   KSR G      GG   QKAAAAG 
Sbjct: 737 AKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGG---QKAAAAGG 793

Query: 287 -----AKSRGGRGEKPQKAEAG 303
                 KSRGGRG   QKA AG
Sbjct: 794 KKPPRVKSRGGRG---QKAAAG 812



 Score =  107 bits (267), Expect = 2e-23
 Identities = 120/315 (38%), Positives = 147/315 (46%), Gaps = 73/315 (23%)

Query: 61  RSHPITPAPALLLLSH-SLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCP 119
           R+ P  P  A L  +   L A+  +   + A AG    G   K+ RR+++       R  
Sbjct: 15  RAGPGAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDKKLRRQKAAAGGKKARLR 74

Query: 120 YQDASRAGSRVCR--------SRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGA 171
            Q  + AG    +           +NRGGG++K    G    KS GG G+KPR       
Sbjct: 75  GQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAG---TKSLGGRGRKPR-----RR 126

Query: 172 GAKK----HRKPRRRGERAAAAGGKK----LQKAAAA---KSRGG-GGKKTAAAG----- 214
           G K      +KPR R +++AAAG K      QKAAAA   KS+GG   +K AAAG     
Sbjct: 127 GQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRS 186

Query: 215 GKKPRRR----RG-------QKAAKS-----RGGGDKKLERQKAALTGVKSR--GDKKPL 256
           GKKPRRR    RG       Q+ AKS     RGG  KK  R K A  G KSR  G KKP 
Sbjct: 187 GKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPAAGGAKSRRGGGKKP- 245

Query: 257 RGGKKQRERGQNT---------KSRGGGGEK----PQKAAAAGAKSRGG--RGEKPQKAE 301
              +KQR RGQ           KSRGGG +K     Q AA AGAK RG    GEKP  A 
Sbjct: 246 ---QKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKP--AA 300

Query: 302 AGQGQNRRNEVGGQH 316
            G+G      +GGQ+
Sbjct: 301 KGRGGRGPKSLGGQN 315



 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 72/167 (43%), Positives = 85/167 (50%), Gaps = 37/167 (22%)

Query: 79  PAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTR------SAPRRCPYQDASRAGSRVCR 132
           PA   S  +  A  G     R  K+PRRR + +R      +A    P+Q   R G +   
Sbjct: 666 PAAAGSESSAAAAVGQEAEAR--KKPRRRRAKSRGDGGQNAAVGINPWQ---RRGKKPRL 720

Query: 133 SRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPR-GQKAA------GAGAKKHR---KPRRR 182
            +  +RGGG  K   RG   AKSRG GG K R G+KAA      G GAK+ R      R 
Sbjct: 721 GK--SRGGGGAK--SRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRS 776

Query: 183 GERAAAAGGKKLQKAAAA--------KSRGGGGKKTAAAGGKKPRRR 221
           GE+A  AGG   QKAAAA        KSRGG G+K AAAGGKKP RR
Sbjct: 777 GEKAVTAGG---QKAAAAGGKKPPRVKSRGGRGQK-AAAGGKKPLRR 819



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 71/198 (35%), Positives = 96/198 (48%), Gaps = 39/198 (19%)

Query: 75  SHSLPAQRRSMQATVAK----AGSPGRGRLGKEPRRRE---SWTRSAPRRCPYQDASRAG 127
           S   P +R    A  A+     G+  RG  GK+PR ++   + + S+      Q+A  A 
Sbjct: 628 SRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAE-AR 686

Query: 128 SRVCRSRPQNRGGGDKKP-------RRRGQKA--AKSRGGGGKKPRGQ---KAAGAGAKK 175
            +  R R ++RG G +         +RRG+K    KSRGGGG K RG    K+ G+G  K
Sbjct: 687 KKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAK 746

Query: 176 HRKPRRRGERAAAA-----GGKKLQKAAAAKSRGG-------GGKKTAAAGGKKPRR--R 221
            R     G++AAA+     GG K ++   AKSR G       G K  AAAGGKKP R   
Sbjct: 747 SRS----GKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKA-AAAGGKKPPRVKS 801

Query: 222 RGQKAAKSRGGGDKKLER 239
           RG +  K+  GG K L R
Sbjct: 802 RGGRGQKAAAGGKKPLRR 819


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 58/254 (22%), Positives = 111/254 (43%), Gaps = 30/254 (11%)

Query: 76  HSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRV-CRSR 134
           HS  ++ RS  +  + + S  R R G   R + S +RS  R    ++ SR+ S+   RSR
Sbjct: 200 HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSK-SRSRSQSRSRSKKEKSRSPSKEKSRSR 258

Query: 135 PQNRGGGDKKPRRRGQKAAKSRGGGGK----KPRGQKAAGAGAKKHRKPR----RRGERA 186
             + G    K + + ++  ++    GK     P   K+      + ++ R    +RG  +
Sbjct: 259 SHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVS 318

Query: 187 AAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPR-----RRRGQKAAKSRGGGDKKLERQK 241
                +K  + + ++SR  GG ++ +    K +     R+R ++ ++SR     K ER  
Sbjct: 319 RGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERS- 377

Query: 242 AALTGVKSRGDKKPLRGGKKQRERGQNT-----KSRGGGGEKPQKAAAAGAKSRGGRGEK 296
                 + RG K+  + G  ++++ ++T     +S      K ++ A + +  R GRGE 
Sbjct: 378 ------RKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE- 430

Query: 297 PQKAEAGQGQNRRN 310
                AG  Q  R+
Sbjct: 431 --SENAGTNQETRS 442



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 58/253 (22%), Positives = 105/253 (41%), Gaps = 21/253 (8%)

Query: 81  QRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRV---CRSRPQN 137
           +RRS   + + + S  R R  ++ R R   ++S+  +   +  SR+GSR     RSR Q+
Sbjct: 181 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKS--RSRSRSGSRSRSKSRSRSQS 238

Query: 138 RGGGDK---------KPRRRGQKAAKSRGGGGKKPRG--QKAAGAGAKKHRKPRRRGERA 186
           R    K         K R R   A KSR     +     Q     G  K R P R   ++
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298

Query: 187 AAAGGKKLQKAAAAK----SRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKA 242
            +    + ++    K    SRG   +K+      + R + G ++ +SR     K +R+  
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS-RSRSRSKSKDKRKGR 357

Query: 243 ALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEA 302
             +  +SR   +     ++ R+RG    S+ G  +K +K     ++SR       ++ E 
Sbjct: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREH 417

Query: 303 GQGQNRRNEVGGQ 315
            + ++ + E  G+
Sbjct: 418 AKSESSQREGRGE 430



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 55/231 (23%), Positives = 95/231 (41%), Gaps = 32/231 (13%)

Query: 105 RRRESWTRSAPRRCPYQDASRAG-SRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKP 163
           RRR S++RS   R   +  SR+  SR  RSR  +      K R R +  ++SR     + 
Sbjct: 180 RRRRSYSRS---RSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR--SKSRS 234

Query: 164 RGQKAAGAGAKKHRKPRRRGERAAA-AGGKKLQKA--------------AAAKSRGGGGK 208
           R Q  + +  +K R P +   R+ + + GK   K+                 KSR     
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294

Query: 209 KTAAAGGKKPRRRR---GQKAAKSRGGGDKKLERQKAALTGVK--------SRGDKKPLR 257
           K+ +    + + RR    ++ + SRG   +K  RQ  + +  K        SR   K  R
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354

Query: 258 GGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNR 308
            G+K+      ++SR     +  +   +   S+ G  +K +K +  + Q+R
Sbjct: 355 KGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR 405



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 50/216 (23%), Positives = 94/216 (43%), Gaps = 25/216 (11%)

Query: 94  SPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAA 153
           S  + R   + RR E   R +  R   Q+ S    R  RSR +++GG     R R +  +
Sbjct: 296 SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSL---RQSRSRSRSKGGS----RSRSRSRS 348

Query: 154 KSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAA 213
           KS+     K +G+K +   ++   + R + ER+   G K+  KA ++K +          
Sbjct: 349 KSK----DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK---------- 394

Query: 214 GGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQ-NTKSR 272
             KK    R Q  + SR    K+ E  K+  +  + RG+ +     ++ R R + N+KS+
Sbjct: 395 --KKEDTDRSQSRSPSR-SVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSK 451

Query: 273 GGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNR 308
                + +  + + +K+R     + + A     ++R
Sbjct: 452 PNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSR 487



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 41/179 (22%), Positives = 70/179 (39%), Gaps = 26/179 (14%)

Query: 125 RAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGE 184
           + GSR  RS  ++R     + R R  + ++SR G  K              H K R R  
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSK------------SSHSKSRSRSR 223

Query: 185 RAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAAL 244
             + +  K   +   ++SR    K+ + +  K+  R R   A KSR     + E +    
Sbjct: 224 SGSRSRSKSRSR---SQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNN 280

Query: 245 TGVKSRGDKKPLRGGKKQRERGQNTK-----------SRGGGGEKPQKAAAAGAKSRGG 292
             V     + P R   K + R ++ +           SRG   EK  + + + ++S+GG
Sbjct: 281 DNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGG 339



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 44/192 (22%), Positives = 81/192 (42%), Gaps = 21/192 (10%)

Query: 91  KAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQ 150
           K GS  RGR  +E   R+S +RS          S+ GSR  RSR +++    +K R+R +
Sbjct: 313 KRGSVSRGR-SQEKSLRQSRSRSR---------SKGGSR-SRSRSRSKSKDKRKGRKRSR 361

Query: 151 KAAKSRGGGGKKPRGQKAAG------AGAKKHRKP----RRRGERAAAAGGKKLQKAAAA 200
           + ++SR     K    +  G      AG+ K +K     R +    + +  K+ + A + 
Sbjct: 362 EESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSE 421

Query: 201 KSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGK 260
            S+  G  ++  AG  +  R R +  +KS+     +   +  + +  +SR   +     +
Sbjct: 422 SSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASR 481

Query: 261 KQRERGQNTKSR 272
                   + SR
Sbjct: 482 SPSRSRSRSHSR 493



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 36/154 (23%), Positives = 57/154 (37%), Gaps = 7/154 (4%)

Query: 160 GKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPR 219
           G +  G+K      K   + RR   R+ +    + +   + KSR   G   ++    + R
Sbjct: 162 GTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSR 221

Query: 220 RRRGQKA-AKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEK 278
            R G ++ +KSR     +   +K      KSR   K     +        +KS+    EK
Sbjct: 222 SRSGSRSRSKSRSRSQSRSRSKKE-----KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEK 276

Query: 279 PQKAAAAG-AKSRGGRGEKPQKAEAGQGQNRRNE 311
            Q     G  KSR     K +     + Q RR E
Sbjct: 277 IQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVE 310



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 39/182 (21%), Positives = 67/182 (36%), Gaps = 19/182 (10%)

Query: 149 GQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGK 208
           G+K        G + R   +      + R   R   ++ +  G      + ++SR   G 
Sbjct: 167 GRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGS 226

Query: 209 KTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLR----------G 258
           ++ +    + + R   K  KSR    +K  R ++   G KSR   K             G
Sbjct: 227 RSRSKSRSRSQSRSRSKKEKSRSPSKEK-SRSRSHSAG-KSRSKSKDQAEEKIQNNDNVG 284

Query: 259 GKKQRERGQN---TKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNRRNEVGGQ 315
             K R   ++   +KSR    E+  +    G+ SRG   EK  +    Q ++R    GG 
Sbjct: 285 KPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLR----QSRSRSRSKGGS 340

Query: 316 HN 317
            +
Sbjct: 341 RS 342


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 69/282 (24%), Positives = 116/282 (41%), Gaps = 39/282 (13%)

Query: 30   PVQAAEGDADELLELPALLQRPAGRGPCATLRS-HPITPAPALLLLSHSLPAQRRSMQAT 88
            P ++  G + E+ + P    R A R    +  S  P  PAP       +LP + RS    
Sbjct: 1593 PRRSRSGSSPEVKDKP----RAAPRAQSGSDSSPEPKAPAP------RALPRRSRS---- 1638

Query: 89   VAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRR 148
                GS  +GR G  P    S T S+P   P    +R GSR   S P+ +      PRRR
Sbjct: 1639 ----GSSSKGR-GPSPEGSSS-TESSPEHPPKSRTARRGSR---SSPEPKTKSRTPPRRR 1689

Query: 149  GQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGK 208
              +++       +  R  ++A +  +   +   R  R+ +    +     A KSR    +
Sbjct: 1690 SSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPE----PAEKSRSSRRR 1745

Query: 209  KTAAAGGKKPRRRRGQKAA-KSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQ 267
            ++A++   K   RRG+  + K RG     L+R ++     K+R  ++  R G  Q    +
Sbjct: 1746 RSASSPRTKTTSRRGRSPSPKPRG-----LQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800

Query: 268  NTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNRR 309
              +SR       ++   +G  SR      P + E+ +  +RR
Sbjct: 1801 RQRSRSRSRVTRRRRGGSGYHSR-----SPARQESSRTSSRR 1837



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 55/254 (21%), Positives = 93/254 (36%), Gaps = 24/254 (9%)

Query: 75  SHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSR 134
           SHS    RR  ++        GR R     +R  S +RS     P    SR+  R  RSR
Sbjct: 472 SHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRS-----PQWRRSRSAQRWGRSR 526

Query: 135 PQNRGGGDKKPRRRG-------QKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAA 187
              R G  + P+R G       Q+  +SR     +   +  A  G  + R P RRG   +
Sbjct: 527 SPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS 586

Query: 188 AAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGV 247
               ++  ++     R    +  A  G     R R +  A+ R      + R+  + +  
Sbjct: 587 RTPARRRSRSRTPTRRRSRSRTPARRG-----RSRSRTPARRRSRTRSPVRRRSRSRSPA 641

Query: 248 KSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQN 307
           +  G  +     ++ R R +    RG       ++ +     R GR      A  G+ ++
Sbjct: 642 RRSGRSRSRTPARRGRSRSRTPARRG-------RSRSRTPARRSGRSRSRTPARRGRSRS 694

Query: 308 RRNEVGGQHNLALL 321
           R    G   + +L+
Sbjct: 695 RTPRRGRSRSRSLV 708



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 60/264 (22%), Positives = 101/264 (38%), Gaps = 18/264 (6%)

Query: 50  RPAGRGPCATLRSHPITPAPALLLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRES 109
           R A RG     RSH  +PA      S +   + RS   T A+  S  R      P RR S
Sbjct: 555 RSARRG-----RSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSR-----TPTRRRS 604

Query: 110 WTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAA 169
            +R+  RR   +  + A  R     P  R    + P RR  ++         + R +  A
Sbjct: 605 RSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPA 664

Query: 170 GAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKS 229
             G  + R P RR  R+ +    +  ++ +   R G  +  +     +   R  Q+  +S
Sbjct: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS 724

Query: 230 RGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKS 289
               ++K    K+  +  +SR +  P    + ++ R  + +SR     +  KA +  +  
Sbjct: 725 GSSSERK---NKSRTSQRRSRSNSSP----EMKKSRISSRRSRSLSSPR-SKAKSRLSLR 776

Query: 290 RGGRGEKPQKAEAGQGQNRRNEVG 313
           R   G  P   +  Q   RR+  G
Sbjct: 777 RSLSGSSPCPKQKSQTPPRRSRSG 800



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 49/221 (22%), Positives = 80/221 (36%), Gaps = 16/221 (7%)

Query: 94   SPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAA 153
            SPG   + + P R  S   S+P         R  SR   S   N      +  R G +++
Sbjct: 1463 SPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESS 1522

Query: 154  KSRGGGGKKPRGQKAAGAGA-----KKHRKPRRRGERAAAAGGK-KLQKAAAAKSRGGGG 207
              +    + P GQ++    +     K    P+ R E  ++   K K +     +SR G  
Sbjct: 1523 VDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSS 1582

Query: 208  KKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQ 267
             +  +     PRR        SR G   +++ +  A    +S  D  P    K    R  
Sbjct: 1583 PEVDSKSRLSPRR--------SRSGSSPEVKDKPRAAPRAQSGSDSSP--EPKAPAPRAL 1632

Query: 268  NTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNR 308
              +SR G   K +  +  G+ S     E P K+   +  +R
Sbjct: 1633 PRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSR 1673



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 59/291 (20%), Positives = 110/291 (37%), Gaps = 16/291 (5%)

Query: 22   GHSALGAQPVQAAEGDADELLELPALLQRPAGRGPCATLRSHPITPAPALLLLSHSLPAQ 81
            G S+ G  P        +   E P    R A RG  ++      +  P     S S P  
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPPK-SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPEL 1697

Query: 82   RRSMQAT--VAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVC--RSRPQN 137
             R  + +     A S    R    PR R S + S+P       +SR        R++  +
Sbjct: 1698 TRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS 1757

Query: 138  RGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKA 197
            R G    P+ RG + ++SR    K    ++   +G+ +    RR+  R+ +   ++ +  
Sbjct: 1758 RRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGG 1817

Query: 198  AAAKSRGGGGKKTAAAGGKKPRRR-----RGQKAAKSR-GGGDKKLERQKAALTGVKSRG 251
            +   SR    ++++    ++ R R       +K ++SR      K  R +A+    +   
Sbjct: 1818 SGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR 1877

Query: 252  DKKPLRGGKKQRER-----GQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKP 297
             + PL   ++ R R      + ++SR     +  ++ A+    R  R   P
Sbjct: 1878 SRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTP 1928



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 32/140 (22%), Positives = 53/140 (37%), Gaps = 13/140 (9%)

Query: 174 KKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGG 233
           KK +K + RG R+ ++  ++ +K ++ K      KK  +    K R+ R       R   
Sbjct: 188 KKKKKKKDRGRRSESSSPRRERKKSSKK------KKHRSESESKKRKHRSPTPKSKRKSK 241

Query: 234 DKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGR 293
           DKK +R ++     KSR   +              ++SR         AA     +  GR
Sbjct: 242 DKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSA-------AAKTHTTALAGR 294

Query: 294 GEKPQKAEAGQGQNRRNEVG 313
              P     G+G    +E G
Sbjct: 295 SPSPASGRRGEGDAPFSEPG 314



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 59/295 (20%), Positives = 101/295 (34%), Gaps = 32/295 (10%)

Query: 45  PALLQRPAGRG-PCAT--LRSHPITP-APALLLLSHSLPAQRRSMQATVAKAGSPGRGRL 100
           P L +R  G   P AT  L   P+ P + A      S P     +  + +   SP   + 
Sbjct: 368 PLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQP 427

Query: 101 GKEPRRRESWTRSA-PRRCPYQDASRAGSRVCRSRPQNRGGGDKK-----PRRRGQKAAK 154
            K  R   S   S  P   P      + S   ++R   R   DK       RR G+  + 
Sbjct: 428 TKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSP 487

Query: 155 SRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSR-----GGGGKK 209
           +    G+  R +     G  + R P+ R  R+A   G+        +SR     G    +
Sbjct: 488 ATAKRGRS-RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSR 546

Query: 210 TAAAGGKKPRRRRGQKAAKS--------------RGGGDKKLERQKAALTGVKSRGDKKP 255
                G+    RRG+  ++S              RG    +   ++ + +   +R   + 
Sbjct: 547 NTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRS 606

Query: 256 LRGGKKQRERGQNTKSRGGGGEKP--QKAAAAGAKSRGGRGEKPQKAEAGQGQNR 308
               ++ R R +    R      P  +++ +     R GR      A  G+ ++R
Sbjct: 607 RTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSR 661



 Score = 32.3 bits (72), Expect = 0.65
 Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 5/101 (4%)

Query: 145 PRRRGQKAAKSRG--GGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKS 202
           P+++ +K  K RG       PR ++   +  KKHR      +R   +   K ++ +  K 
Sbjct: 185 PKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKK 244

Query: 203 RGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAA 243
           R      T A    K RR     +A S    D    R ++A
Sbjct: 245 RKRSRSTTPA---PKSRRAHRSTSADSASSSDTSRSRSRSA 282



 Score = 32.3 bits (72), Expect = 0.65
 Identities = 31/170 (18%), Positives = 62/170 (36%), Gaps = 7/170 (4%)

Query: 143 KKPRRRGQKAAKS-----RGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKA 197
           KK + RG+++  S     R    KK + +  + +  +KHR P  + +R +    +K  ++
Sbjct: 191 KKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRS 250

Query: 198 A--AAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKP 255
              A KSR      +A +       R   ++A ++        R  +  +G +  GD   
Sbjct: 251 TTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPF 310

Query: 256 LRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQG 305
              G    +R  + ++       P +      K +      P    +  G
Sbjct: 311 SEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 63/248 (25%), Positives = 97/248 (39%), Gaps = 30/248 (12%)

Query: 61  RSHPITPAPALLLLSHSLPAQRR-SMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCP 119
           +  P T +P      HS  +    S+ +  + + SP R      P+ R+   ++  +R  
Sbjct: 240 KKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSR----LSPKHRDEGRKTGSQRS- 294

Query: 120 YQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKP 179
                 +GSR   S   + G G   P+R G    +S   GG+   G   +         P
Sbjct: 295 ------SGSR---SPSPSGGSGWGSPQRNGGSGQRSGAHGGRP--GSAHSPPDKPSSPSP 343

Query: 180 RRRGERAAAA------GGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGG 233
           R R + AAAA      G +     +A  S+G GG+   AAGG   RRRR ++  +SR   
Sbjct: 344 RVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGR---AAGGAGRRRRRRRRRRRSRSSA 400

Query: 234 DKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGR 293
                R +        RG  + L   +   + G     RG  G  P+  +  G    G R
Sbjct: 401 SAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSG---SGRGAPGPGPEPGSERGHGGHGKR 457

Query: 294 G-EKPQKA 300
             E+P +A
Sbjct: 458 AKERPPRA 465



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 64/253 (25%), Positives = 97/253 (38%), Gaps = 37/253 (14%)

Query: 50  RPAGRGPCATLRSHPITPAPALLLLSHSLPAQRRSMQATVAKA-GSPGRGRLGKEPRRRE 108
           +P+   P    ++    P P         P    S Q    +A G  GR R  +  RRR 
Sbjct: 337 KPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRS 396

Query: 109 SWTRSAPRR--------CPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGG 160
             + SAPRR         P + +SR+ SR   S     G G   P   G +    RG GG
Sbjct: 397 RSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGP---GPEPGSERGHGG 453

Query: 161 KKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGG--GKKTAAAGGKKP 218
               G++A      K R PR R    + + G        A  R GG  GK ++ + G  P
Sbjct: 454 ---HGKRA------KERPPRARPASTSPSPG--------AHGRRGGPEGKSSSRSPGPHP 496

Query: 219 RRRRGQKA-AKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGE 277
           R     ++ +KSR    +K     +     +S   KKPL   K    R +++++      
Sbjct: 497 RSWSSSRSPSKSRSRSAEKRPHSPS-----RSPSPKKPLSRDKDGEGRARHSEAEATRAR 551

Query: 278 KPQKAAAAGAKSR 290
           +  ++ +   K R
Sbjct: 552 RRSRSYSPIRKRR 564



 Score = 36.6 bits (83), Expect = 0.035
 Identities = 45/230 (19%), Positives = 78/230 (33%), Gaps = 22/230 (9%)

Query: 101 GKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNR-----GGGDKKPRRRGQKAAKS 155
           G    R + W+ S+    P +   + G    RSR + R       G   P R+ +K+ K 
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHR-RSRKKRRLESECSCGSSSPLRKKKKSVKK 208

Query: 156 R-----GGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKT 210
                   G ++ R  ++  +  K+  K + +      + G++  + ++  S        
Sbjct: 209 HRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSH 268

Query: 211 AAAGGKKPR-----RRRGQKAAKSRGGGDKKLERQKAALTGVKSR----GDKKPLRGGKK 261
            +      R     R  G+K    R  G +       +  G   R    G +    GG+ 
Sbjct: 269 YSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRP 328

Query: 262 QRERGQNTKSRGGGGEKPQKAAAAGAK--SRGGRGEKPQKAEAGQGQNRR 309
                   K          KAAAA     +RG     P+ A + QG+  R
Sbjct: 329 GSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGR 378



 Score = 32.0 bits (71), Expect = 0.85
 Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 5/99 (5%)

Query: 225 KAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQ---K 281
           K  K + GG ++  R+K  L    S G   PLR  KK  ++ +  +S  G   K +   +
Sbjct: 169 KKKKKKKGGHRR-SRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSR 227

Query: 282 AAAAGAKSRGGRGEKPQKAEAGQGQNRRNEVGGQHNLAL 320
           ++    K +    ++P     G+ ++ R+  G  H+ +L
Sbjct: 228 SSKCKRKEKNKEKKRPHTESPGR-RSHRHSSGSSHSPSL 265


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 49/184 (26%), Positives = 79/184 (42%), Gaps = 17/184 (9%)

Query: 128 SRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAA 187
           S+ C  R   R    KK RR  +K  + R    K+ RG+K      KK RK R RG+   
Sbjct: 26  SKPCTQRESER----KKERREREKRKREREKERKRERGKKE-----KKKRKKRERGKERE 76

Query: 188 AAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGV 247
               +K ++    + R    +K      K+ R++RG++  K      KK ER++      
Sbjct: 77  RK--RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERK------KKKERKERERENK 128

Query: 248 KSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQN 307
           + R  K+  R  KK+R+  +  K RG    K +K      + +  R  K +K E  + + 
Sbjct: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188

Query: 308 RRNE 311
           R  +
Sbjct: 189 RERK 192



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 36/168 (21%), Positives = 79/168 (47%), Gaps = 8/168 (4%)

Query: 105 RRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPR 164
           R++E   R   +R   ++  R   +  + + + R  G ++ R+R ++  + +    K+ R
Sbjct: 36  RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95

Query: 165 GQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQ 224
            +K      KK R+ ++RG R      ++ ++    K R    +K      +K +RR+ +
Sbjct: 96  KRKKE----KKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR----RKKKRRKER 147

Query: 225 KAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSR 272
           K  K RG  ++K +++K      K   ++K  +  ++++ER +  K R
Sbjct: 148 KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKER 195



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 38/173 (21%), Positives = 75/173 (43%), Gaps = 1/173 (0%)

Query: 99  RLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGG 158
           R  +E R+RE        R   +   R      + R + R   +K+ + R +K  + R  
Sbjct: 40  RREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKK 99

Query: 159 GGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKP 218
             KK R +K  G   +K +K R+  ER      ++ +K    K R    K+    G ++ 
Sbjct: 100 E-KKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRER 158

Query: 219 RRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKS 271
           +R++ +K  + +     + ER+K      +    K+  +  +K++ER ++ K+
Sbjct: 159 KRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKT 211



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 36/153 (23%), Positives = 64/153 (41%), Gaps = 11/153 (7%)

Query: 97  RGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSR 156
           RG+  K+ R++    +   R+   ++  R   R    R + +    ++ ++RG++  K +
Sbjct: 58  RGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKK 117

Query: 157 GGGGKKPRGQKAAGAGAKKHR--KPRRRGERAAAAGG------KKLQKAAAAKSRGGGGK 208
               ++ R  K      +K R  K RR+  +     G      KK +K    K R    K
Sbjct: 118 KERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRK 177

Query: 209 KTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQK 241
           +      +K RR R ++  K R    KK ER+K
Sbjct: 178 ERKKERERKERRERKKERKKER---RKKKERKK 207



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 35/139 (25%), Positives = 62/139 (44%), Gaps = 15/139 (10%)

Query: 177 RKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKK 236
           R+  R+ ER      K+ ++    + RG   KK      K+ +R RG++  + R    K+
Sbjct: 32  RESERKKERREREKRKREREKERKRERGKKEKK------KRKKRERGKERERKR----KE 81

Query: 237 LERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEK 296
            E+Q+      + R  KK     KK+RER Q  + R    +K +K      K R  R  K
Sbjct: 82  REKQRKERREKERRKRKKE----KKKRERKQRGR-RERKKKKERKERERENKQRRERKRK 136

Query: 297 PQKAEAGQGQNRRNEVGGQ 315
            ++ +  + + +R +  G+
Sbjct: 137 KRRKKKRRKERKREKERGK 155


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 56/236 (23%), Positives = 90/236 (38%), Gaps = 12/236 (5%)

Query: 34  AEGDADELLELPALLQRPAGRGPCATLRSHPITPAPALLLLSHSLPAQRRSMQATV---- 89
           AE D +  L++   L  PA   P A  R   +     +L        QR    A      
Sbjct: 451 AESDGEGALQVD--LGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPA 508

Query: 90  AKAGSPGRGRLGKEPRR-----RESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGG-GDK 143
           A AG P R +  +E +R       + + S  +  P   AS   S+  RSR +  G     
Sbjct: 509 AAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASS 568

Query: 144 KPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSR 203
             RRR +  ++SR    +     +  G   +   + +RR  R +A+       +++++  
Sbjct: 569 SARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRE 628

Query: 204 GGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGG 259
              GK     G KK ++R   +  K  G G +K        +G  S GD+   R G
Sbjct: 629 RHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRG 684



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 46/200 (23%), Positives = 91/200 (45%), Gaps = 24/200 (12%)

Query: 105 RRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQ-KAAKSRGGGGKKP 163
           +RRE + + +P   P      A +    + P  R    ++ +R G+ K A S   G +  
Sbjct: 489 QRRERYRQRSPSPAP------APAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPA 542

Query: 164 RGQKAAGAGAKKHR-KPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRR 222
               A+   +KKHR + R+ G  A+++  ++ +  + ++S     + T        RRR 
Sbjct: 543 PPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRST-------DRRRG 595

Query: 223 GQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKA 282
           G + ++SR   +K+  R+++A     +          +++R RG++    GGG +K +K 
Sbjct: 596 GSRRSRSR---EKRRRRRRSASPPPATSSSSS----SRRERHRGKHRD--GGGSKKKKKR 646

Query: 283 AAAGAKSRGGRGEKPQKAEA 302
           + +  + R G G +   A A
Sbjct: 647 SRSRGEKRSGDGSEKAPAPA 666



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 82/327 (25%), Positives = 118/327 (36%), Gaps = 59/327 (18%)

Query: 36  GDADELLELPALLQRPAGRGPCATLRSHPITPAPALL--LLSHSLPAQRRSMQA------ 87
           GD  E  + PA    P+G   C    S      P  +  L  H L A +R++        
Sbjct: 656 GDGSE--KAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKS 713

Query: 88  -----TVAKAGSPGRGRL----GKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNR 138
                + A A SP R  L    G     R   +    RR     +S + SR   SR +  
Sbjct: 714 DPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKAL 773

Query: 139 GGGDKKPRRRGQKAAKSRGGGGKKPRGQK-AAGAGAKKHRKPRRRGERAAAAGGK----- 192
            GGD   R R +   + R    KK R  K +A +     + P   G  ++++        
Sbjct: 774 DGGD---RDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRK 830

Query: 193 -KLQKAAAAKSRGGGGKKT----AAAGGK------------------KPRRRRGQKAAKS 229
            KLQ   A   R G    T    AA+ G                   KP  R   + AK+
Sbjct: 831 VKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKA 890

Query: 230 RGGGDKKLERQKAALTGVK----SRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAA 285
             G  K  + +  A  G K    ++G  KP +  KK R  G    S G GG+   K + A
Sbjct: 891 APGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGG---GSGGSGGQVSLKKSKA 947

Query: 286 GAKSRGGRGEKPQKAEAGQGQNRRNEV 312
            + S+   G K  +  +  G+ R  +V
Sbjct: 948 DSCSQAA-GTKGAEETSWSGEERAAKV 973


>gi|239755739 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 51/182 (28%), Positives = 75/182 (41%), Gaps = 44/182 (24%)

Query: 157 GGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGK 216
           G GG++ +G   AG  A K ++P          G  +++ A A   RGGG ++  A G +
Sbjct: 24  GWGGEEVQGLARAGLAAGKGQRP---------PGPGRVRAAQARARRGGGARERPAEGAR 74

Query: 217 KPRRRRGQKAAKSRGGGDKKLE--------------RQKAALTG----------VKSRGD 252
            PR  RG     +R G D +L               R++AA  G           +S G 
Sbjct: 75  GPRAARG----GARAGPDAQLRAARTHRARAQTPQLRREAACAGSFFFRKCRQSPRSHGQ 130

Query: 253 KKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKP------QKAEAGQGQ 306
             P      Q  R Q   ++ GGG +P +   A A + GG+   P       +A AGQG 
Sbjct: 131 PFPQLRSHWQAPR-QGWPAQEGGGRRPSRREEAAALAGGGKRTAPGLRGRGGRAAAGQGG 189

Query: 307 NR 308
           +R
Sbjct: 190 DR 191



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 40/160 (25%), Positives = 66/160 (41%), Gaps = 26/160 (16%)

Query: 129 RVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQ-KAAGAGAKKHRKPRRRGERAA 187
           R  ++R +  GG  ++P    +    +RGG    P  Q +AA     + + P+ R E AA
Sbjct: 53  RAAQARARRGGGARERPAEGARGPRAARGGARAGPDAQLRAARTHRARAQTPQLRRE-AA 111

Query: 188 AAGGKKLQKAAAAKSRGG--------------GGKKTAAAGGKKPRRRRGQKAAKSRGGG 233
            AG    +K   +    G               G      GG++P RR  ++AA   GGG
Sbjct: 112 CAGSFFFRKCRQSPRSHGQPFPQLRSHWQAPRQGWPAQEGGGRRPSRR--EEAAALAGGG 169

Query: 234 DKKLERQKAALTGVKSRGDKKPL-RGGKKQRERGQNTKSR 272
                  K    G++ RG +    +GG +  +R +  +S+
Sbjct: 170 -------KRTAPGLRGRGGRAAAGQGGDRHPDRWRRQRSK 202


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 46/178 (25%), Positives = 81/178 (45%), Gaps = 5/178 (2%)

Query: 143 KKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKH---RKPRRRGERAAAAGGKKLQKAAA 199
           KK RR  +K  + R    K+ RG+K      KK    RK RRR +       K+ +K   
Sbjct: 60  KKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE 119

Query: 200 AKSRGGGGKKTAAAGGKKPRRRRGQK-AAKSRGGGDKKLERQKAALTGVKSRGDKKPLRG 258
            K RG   K+      K+ R+R  +K   + +   +K+ ER++      K  G+K+  R 
Sbjct: 120 KKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERK 179

Query: 259 GKKQRERGQNTKSR-GGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNRRNEVGGQ 315
            K+++ER +  ++R     E+ +K      K R  + E+ ++ +  +  N R +  G+
Sbjct: 180 EKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGK 237



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 48/205 (23%), Positives = 90/205 (43%), Gaps = 14/205 (6%)

Query: 103 EPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKK 162
           E R+     R + R+   ++  +      + R + RG  +KK  R+ ++  +      KK
Sbjct: 46  ETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER------KK 99

Query: 163 PRGQKAAGAGAKKH-RKPRRRGERAAAAG-GKKLQKAAAAKSRGGGGKKTAAAGGKKPRR 220
            R +K    G +K  RK + + ER   +  GK+ ++    K      ++      +K R 
Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERE 159

Query: 221 RRGQKAAKSRGGGDKKLERQ----KAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGG 276
           R+ +K  + +  G+K+ ER+    K      ++R ++K  R  K++RER +  K +    
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERK 219

Query: 277 EKPQKAAAAG--AKSRGGRGEKPQK 299
           ++ QK        K RG R  K +K
Sbjct: 220 KERQKDRQTNWREKERGKRERKERK 244



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 7/112 (6%)

Query: 207 GKKTAAAGGKKPRRRRGQKAA-------KSRGGGDKKLERQKAALTGVKSRGDKKPLRGG 259
           GKK   +  KK RR R ++         + RG  +KK ER+K      K R +K+   G 
Sbjct: 51  GKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGE 110

Query: 260 KKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNRRNE 311
           +K++ + +  K RG   ++ ++      + R  R E+ +K E  + +  R E
Sbjct: 111 EKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 28/136 (20%), Positives = 62/136 (45%)

Query: 174 KKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGG 233
           KK R+  R+ ER      K+ ++    + RG   KK      ++ R++R ++     G  
Sbjct: 52  KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111

Query: 234 DKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGR 293
            +K ++++    G  S+  K+  R  +++RE  +  + +    EK ++      + R   
Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171

Query: 294 GEKPQKAEAGQGQNRR 309
           GEK ++ +  + + R+
Sbjct: 172 GEKEEERKEKERKERK 187


>gi|239743051 PREDICTED: hypothetical protein XP_002342747 [Homo
           sapiens]
          Length = 306

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 54/233 (23%), Positives = 89/233 (38%), Gaps = 26/233 (11%)

Query: 94  SPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAA 153
           SP   + G + R  E+    AP    ++   R   +     PQ R  G    +RRG +++
Sbjct: 56  SPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ-----PQRRPAGGTG-QRRGSRSS 109

Query: 154 KSRGGGGKKPRGQKAAGAGAK-------KHRKPRRRGERAAAAGGKKL----------QK 196
            S    G + R ++AA A A        + RKP++   R AA  G++           Q+
Sbjct: 110 SSADQQGAQDREEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGSGCSPSADQQR 169

Query: 197 AAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGG-GDKKLERQKAALTGVKSRGDKKP 255
           A   +          ++G +  +R+R Q   +  GG G ++  R   +       G ++ 
Sbjct: 170 AQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSRQPAGGTGQRRG 229

Query: 256 LRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNR 308
            R      +  Q  + R     +PQ+  A G   R G    P     G GQ R
Sbjct: 230 SRSSPSADQ--QRAQDREEEAAQPQRRPAGGTGQRRGTAAAPVPTTGGTGQRR 280



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 59/231 (25%), Positives = 87/231 (37%), Gaps = 47/231 (20%)

Query: 103 EPRRRESWTRSAP-RRCPYQDASRAGSRVCRSRPQNR-----GGGDKKPRRRGQKAAKSR 156
           +PR++E  TR    R     D      +    RPQ +      GG  +  RRG  ++ S 
Sbjct: 2   KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQ--RRGSGSSPSA 59

Query: 157 GGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGK 216
              G + R ++AA A A     P  RG R      ++ Q+  A    GG G++       
Sbjct: 60  DQQGAQDREEEAAAAPA-----PTSRGHRTEKRKPQQPQRRPA----GGTGQR------- 103

Query: 217 KPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRER-GQNTKSRGGG 275
             R  R   +A  +G  D+  E + AA     S G +   R  ++ + R    T  R G 
Sbjct: 104 --RGSRSSSSADQQGAQDR--EEEAAAAPAPTSSGHRTEKRKPQQPQCRPAAGTGQRRGS 159

Query: 276 GEKP------------QKAAAAGAKSRGGRGEKPQKAE------AGQGQNR 308
           G  P            +  AA    S G R EK ++ +       G GQ R
Sbjct: 160 GCSPSADQQRAQDREEEATAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRR 210


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 46/178 (25%), Positives = 71/178 (39%), Gaps = 25/178 (14%)

Query: 51  PAGRGPCATLRSHPITPAPALLLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESW 110
           P    P     + P++PAP   L   ++P             G P  G L  +P+   + 
Sbjct: 90  PPALSPAPASPARPVSPAPGRRLSLWAVPP------------GPPLSGGLSPDPKPGGAP 137

Query: 111 TRS------APRRCPYQDASRAGSRVCRSRPQNRGGGDKK----PRRRGQKAAKSRGGGG 160
           T S      +P     +   RAG  +  S   + G G ++    P     K  K+    G
Sbjct: 138 TSSRRPLLSSPSWGGPEPEGRAGGGIPGSSSPHPGTGSRRLKVAPPPPAPKPCKTVTTSG 197

Query: 161 KKPRGQKAAGAGA---KKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGG 215
            K  G K AG+     +   KPR +G +++A  G  +  AA A + GGGG   + +GG
Sbjct: 198 AKAGGGKGAGSRLSWPESEGKPRVKGSKSSAGTGASVSAAATAAAAGGGGSTASTSGG 255



 Score = 28.5 bits (62), Expect = 9.4
 Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 21/71 (29%)

Query: 126 AGSRVCRSRPQNRGGGDKKPRRRGQKA-------------AKSRGGGGK--KPRGQKAAG 170
           AGSR+  S P++ G    KPR +G K+             A + GGGG      G   AG
Sbjct: 206 AGSRL--SWPESEG----KPRVKGSKSSAGTGASVSAAATAAAAGGGGSTASTSGGVGAG 259

Query: 171 AGAKKHRKPRR 181
           AGA+    PR+
Sbjct: 260 AGARGKLSPRK 270


>gi|24475863 H1 histone family, member O, oocyte-specific [Homo
           sapiens]
          Length = 346

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 43/172 (25%), Positives = 71/172 (41%), Gaps = 11/172 (6%)

Query: 145 PRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRG 204
           P    ++A +++G G KKP   K       K +K  +R  +      K       A+ +G
Sbjct: 142 PATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQG 201

Query: 205 GGGKKTAAAGGKK----PRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGK 260
           G  K T A  G+     P+  +  +A  S GG    L R+  A     S+GD +  R  K
Sbjct: 202 GAAKDTRAQSGEARKVPPKPDKAMRAPSSAGG----LSRKAKAKGSRSSQGDAEAYRKTK 257

Query: 261 KQRERGQNTKSR--GGGGEKPQKAAAAGAKS-RGGRGEKPQKAEAGQGQNRR 309
            + +  + T S+   G     +K   A AK+ + G+G   + A   +G   +
Sbjct: 258 AESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSK 309



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 29/241 (12%)

Query: 40  ELLELPALLQRPAGRGPCATLRSHPITPAPALLLLSHSL-PAQRRSMQAT-VAKAGSPGR 97
           ++L    LL++    G    L + P+         S  L P  ++ +Q   +A A +P R
Sbjct: 89  DVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRR 148

Query: 98  G--RLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQ---------NRGGGDKKPR 146
                GK P++        P     + A++  ++V +  P+          +GG  K  R
Sbjct: 149 AGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTR 208

Query: 147 RRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQ------KAAAA 200
            +  +A K      K  R   +AG  ++K +    R  +  A   +K +      K  A+
Sbjct: 209 AQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTAS 268

Query: 201 KSRGGGG---KKTAAAGGKKPRRRRG---QKAAKSRGGGDK----KLERQKAALTGVKSR 250
           K + G     KK   A  K P+  +G   + AA ++G G K     L R+  A  G +  
Sbjct: 269 KVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKA 328

Query: 251 G 251
           G
Sbjct: 329 G 329



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 38/151 (25%), Positives = 58/151 (38%), Gaps = 11/151 (7%)

Query: 97  RGRLGKEPRRRESWTRSAPRRCP--YQDASRAG--SRVCRSRPQNRGGGDKKPRRRGQKA 152
           +G   K+ R +    R  P +     +  S AG  SR  +++      GD +  R+ +  
Sbjct: 200 QGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAE 259

Query: 153 AKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAA 212
           +KS      KP   K     A   +K      +A  AG     KAAA   +G G K   A
Sbjct: 260 SKS-----SKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPA-KGSGSKVVPA 313

Query: 213 AGGKKPRRRRG-QKAAKSRGGGDKKLERQKA 242
              +K    +G +KA         K+  Q+A
Sbjct: 314 HLSRKTEAPKGPRKAGLPIKASSSKVSSQRA 344


>gi|239754674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 480

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 69/263 (26%), Positives = 90/263 (34%), Gaps = 26/263 (9%)

Query: 54  RGPCATLRSHPITPAPALLLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRS 113
           +G CA L   P  P P L         QR  +            G  G  P+ +    + 
Sbjct: 144 KGLCALLLELPPRPPPNLQEGGQRAIFQRPPVYLGNKPTPPRQEGSFGGRPKSQPPLPQE 203

Query: 114 APRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGA 173
                P    +   +RV    P    G  ++PR R + A           R   A G GA
Sbjct: 204 TAAPAPQPGPTAPPARV--REPGRAEGASREPRLRSRAA-----------RPPPAPGPGA 250

Query: 174 KKHRKPRRRGERAAAAGGKKLQKAAAAKS-RGGGGKKTAAAGGKKPRRRRGQKAAKSRGG 232
              R  R R       G    +KAAA ++  GGGG+   A G   P  R  Q A    G 
Sbjct: 251 LS-RASRSRAAGRPGPGFHGGEKAAAPRAPGGGGGRNPGALGRAAPPSRARQDAWGLSGC 309

Query: 233 GDKKLERQKAALTGVKSRGDKKPLRGGKKQRER-GQNTKSRGGGGEKPQKAAAAGAKSRG 291
               L R      G      + P   G  +R R  +  + RGGGGE     A  G  S  
Sbjct: 310 ATVGLRRGDCDRAG----SSQPPATSGNGERCRFCRRRRRRGGGGEGEGTHATHGPASPP 365

Query: 292 GR------GEKPQKAEAGQGQNR 308
           GR      G    +A +G+G  R
Sbjct: 366 GRRHDEEVGAAVLRAGSGEGSRR 388



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 57/234 (24%), Positives = 87/234 (37%), Gaps = 32/234 (13%)

Query: 79  PAQRRSMQATVAKAGSPGRGR-LGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQN 137
           PA +    A  A+   PGR     +EPR R    R  P   P      A SR  RSR   
Sbjct: 207 PAPQPGPTAPPARVREPGRAEGASREPRLRSRAARPPPAPGP-----GALSRASRSRAAG 261

Query: 138 RGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPR-------------RRGE 184
           R G        G+KAA  R  GG   R   A G  A   R  +             RRG+
Sbjct: 262 RPGPGF---HGGEKAAAPRAPGGGGGRNPGALGRAAPPSRARQDAWGLSGCATVGLRRGD 318

Query: 185 ---------RAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDK 235
                     A +  G++ +     + RGGGG+         P    G++  +  G    
Sbjct: 319 CDRAGSSQPPATSGNGERCRFCRRRRRRGGGGEGEGTHATHGPASPPGRRHDEEVGAAVL 378

Query: 236 KLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEK-PQKAAAAGAK 288
           +    + +  G++     + + G  ++   G+N KS      + P+++ A+G K
Sbjct: 379 RAGSGEGSRRGLQLTPPPRRVHGALQRFGGGRNLKSNWMSTTRTPRRSGASGPK 432


>gi|239750250 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 50/182 (27%), Positives = 74/182 (40%), Gaps = 44/182 (24%)

Query: 157 GGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGK 216
           G GG++ +G   AG    K ++P          G  +++ A A   RGGG ++  A G +
Sbjct: 24  GWGGEEVQGLARAGLATGKGQRP---------PGPGRVRAAQARARRGGGARERPAEGAR 74

Query: 217 KPRRRRGQKAAKSRGGGDKKLE--------------RQKAALTG----------VKSRGD 252
            PR  RG     +R G D +L               R++AA  G           +S G 
Sbjct: 75  GPRAARG----GARAGPDAQLRAARTHRARAQTPQLRREAACAGSFFFRKCRQSPRSHGQ 130

Query: 253 KKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKP------QKAEAGQGQ 306
             P      Q  R Q   ++ GGG +P +   A A + GG+   P       +A AGQG 
Sbjct: 131 PFPQLRSHWQAPR-QGWPAQEGGGRRPSRREEAAALAGGGKRTAPGRRGRGGRAAAGQGG 189

Query: 307 NR 308
           +R
Sbjct: 190 DR 191



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 35/142 (24%), Positives = 54/142 (38%), Gaps = 43/142 (30%)

Query: 129 RVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQ------------------KAAG 170
           R  ++R +  GG  ++P    +    +RGG    P  Q                  +AA 
Sbjct: 53  RAAQARARRGGGARERPAEGARGPRAARGGARAGPDAQLRAARTHRARAQTPQLRREAAC 112

Query: 171 AGA--------------------KKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKT 210
           AG+                    + H +  R+G  A   GG++  +   A +  GGGK+T
Sbjct: 113 AGSFFFRKCRQSPRSHGQPFPQLRSHWQAPRQGWPAQEGGGRRPSRREEAAALAGGGKRT 172

Query: 211 AAAGGKKPRRRRGQKAAKSRGG 232
           A       RR RG +AA  +GG
Sbjct: 173 APG-----RRGRGGRAAAGQGG 189


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 5/131 (3%)

Query: 102 KEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGK 161
           K  RR  S +RS+  R   + +S + SR  RSR ++R     + R R     +SR  G K
Sbjct: 197 KSNRRSRSKSRSSHSRSSSRSSSPSSSR-SRSRSRSRSSSSSQSRSRSSSRERSRSRGSK 255

Query: 162 KPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRR 221
                +++    +    PR+R   ++++  ++ +K + ++S   G +K      + P RR
Sbjct: 256 ----SRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERR 311

Query: 222 RGQKAAKSRGG 232
               +  S  G
Sbjct: 312 HRSSSGSSHSG 322



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 29/149 (19%), Positives = 53/149 (35%), Gaps = 22/149 (14%)

Query: 124 SRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRG 183
           SR+ SR   SR  +R       R R +  ++S      + R                   
Sbjct: 202 SRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR--------------- 246

Query: 184 ERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAA 243
           ER+ + G K    + + +      K++ ++    P R R +  ++S   GD+K  R    
Sbjct: 247 ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRR---- 302

Query: 244 LTGVKSRGDKKPLRGGKKQRERGQNTKSR 272
               +SR  ++  R        G  + S+
Sbjct: 303 ---TRSRSPERRHRSSSGSSHSGSRSSSK 328



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 27/131 (20%), Positives = 59/131 (45%), Gaps = 10/131 (7%)

Query: 192 KKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGG-----DKKLERQKAALTG 246
           KK  + + +KSR    + ++ +    P   R +  ++SR         +   R+++   G
Sbjct: 196 KKSNRRSRSKSRSSHSRSSSRSSS--PSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRG 253

Query: 247 VKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQ 306
            KSR   +  RG    R+R  ++ S     E+ +K + + + S G R ++  ++ + + +
Sbjct: 254 SKSRSSSRSHRGSSSPRKRSYSSSS--SSPERNRKRSRSRSSSSGDRKKRRTRSRSPE-R 310

Query: 307 NRRNEVGGQHN 317
             R+  G  H+
Sbjct: 311 RHRSSSGSSHS 321



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 27/132 (20%), Positives = 57/132 (43%), Gaps = 14/132 (10%)

Query: 143 KKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKS 202
           KK  RR +  ++S        R    + + +    + R R  R++++   + + ++  +S
Sbjct: 196 KKSNRRSRSKSRS-----SHSRSSSRSSSPSSSRSRSRSRS-RSSSSSQSRSRSSSRERS 249

Query: 203 RGGGGKKTAAA---GGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGG 259
           R  G K  +++    G    R+R   ++ S    ++K  R +++     S GD+K  R  
Sbjct: 250 RSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSS-----SSGDRKKRRTR 304

Query: 260 KKQRERGQNTKS 271
            +  ER   + S
Sbjct: 305 SRSPERRHRSSS 316



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 8/98 (8%)

Query: 80  AQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRS-----APRRCPYQDASRAGSRVC-RS 133
           ++ RS  ++ +++ S  R R      +  S +RS     +PR+  Y  +S +  R   RS
Sbjct: 229 SRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRS 288

Query: 134 RPQNRGGGDKKPRRRGQKA--AKSRGGGGKKPRGQKAA 169
           R ++   GD+K RR   ++   + R   G    G +++
Sbjct: 289 RSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 17/106 (16%)

Query: 77  SLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQ 136
           S P+  RS   + +++ S  + R      R  S  RS  R       SR+ SR  R    
Sbjct: 218 SSPSSSRSRSRSRSRSSSSSQSR-----SRSSSRERSRSR----GSKSRSSSRSHR---- 264

Query: 137 NRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRR 182
               G   PR+R   ++ S     +K    +++ +G +K R+ R R
Sbjct: 265 ----GSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR 306


>gi|239753399 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 165

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 49/150 (32%), Positives = 63/150 (42%), Gaps = 27/150 (18%)

Query: 111 TRSAPRRCPYQDASRAGSRV-----CRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRG 165
           TR  PR  PY    + GSR+     C S P    G        G +  + RGGG +    
Sbjct: 4   TRQHPRH-PYP---KVGSRIPSNRKCHSPPPPPSGTLTGAECGGGRGRERRGGGTRHTHH 59

Query: 166 QK---------AAGAGAKKHRKPR--RRGERAAAAGGKKLQKAAAAKSRG---GGGKKTA 211
            +         A GA A   RKPR  R G  A AA  +K ++ A A+ RG   GGG +  
Sbjct: 60  AENCFTAFLKVAEGAAAAAPRKPRTGRGGAAATAAVTRKERETAPARDRGGGDGGGARAD 119

Query: 212 AAGGKKPRRRRGQKA----AKSRGGGDKKL 237
              G+ PRRR   +A      S  G  KK+
Sbjct: 120 GLRGRSPRRRPAGRAHARSLPSAPGSPKKI 149


>gi|239741865 PREDICTED: hypothetical protein XP_002342328 [Homo
           sapiens]
          Length = 165

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 49/150 (32%), Positives = 63/150 (42%), Gaps = 27/150 (18%)

Query: 111 TRSAPRRCPYQDASRAGSRV-----CRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRG 165
           TR  PR  PY    + GSR+     C S P    G        G +  + RGGG +    
Sbjct: 4   TRQHPRH-PYP---KVGSRIPSNRKCHSPPPPPSGTLTGAECGGGRGRERRGGGTRHTHH 59

Query: 166 QK---------AAGAGAKKHRKPR--RRGERAAAAGGKKLQKAAAAKSRG---GGGKKTA 211
            +         A GA A   RKPR  R G  A AA  +K ++ A A+ RG   GGG +  
Sbjct: 60  AENCFTAFLKVAEGAAAAAPRKPRTGRGGAAATAAVTRKERETAPARDRGGGDGGGARAD 119

Query: 212 AAGGKKPRRRRGQKA----AKSRGGGDKKL 237
              G+ PRRR   +A      S  G  KK+
Sbjct: 120 GLRGRSPRRRPAGRAHARSLPSAPGSPKKI 149


>gi|4885381 histone cluster 1, H1b [Homo sapiens]
          Length = 226

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 47/200 (23%), Positives = 83/200 (41%), Gaps = 8/200 (4%)

Query: 49  QRPAGRGPCATLRSHPITPAPALLLLSHSLPAQRRSMQ-ATVAKAGSPGRGRLGKEPRRR 107
           ++ AG G      + P  P   L+  + +   +R  +  A + KA + G   + K   R 
Sbjct: 26  KKAAGAGAAKRKATGP--PVSELITKAVAASKERNGLSLAALKKALAAGGYDVEKNNSRI 83

Query: 108 ESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQK 167
           +   +S   +         G+       +    G+ KP+ +   AAK++   G  P+  K
Sbjct: 84  KLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGATPKKAK 143

Query: 168 AAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPR----RRRG 223
            A    K  +K  ++ ++ AAAG KK+ K +  K++     K A     KP+    +   
Sbjct: 144 KAAGAKKAVKKTPKKAKKPAAAGVKKVAK-SPKKAKAAAKPKKATKSPAKPKAVKPKAAK 202

Query: 224 QKAAKSRGGGDKKLERQKAA 243
            KAAK +    K  + +KAA
Sbjct: 203 PKAAKPKAAKPKAAKAKKAA 222



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 43/150 (28%), Positives = 58/150 (38%), Gaps = 22/150 (14%)

Query: 161 KKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRR 220
           KK   +KAAGAGA K +        A      +L   A A S+   G   AA        
Sbjct: 21  KKKATKKAAGAGAAKRK--------ATGPPVSELITKAVAASKERNGLSLAAL------- 65

Query: 221 RRGQKAAKSRGGGD--KKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEK 278
               K A + GG D  K   R K  L  + S+G     +G         N K+  G   K
Sbjct: 66  ----KKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA-K 120

Query: 279 PQKAAAAGAKSRGGRGEKPQKAEAGQGQNR 308
           P+   A  AK++   G  P+KA+   G  +
Sbjct: 121 PKAKKAGAAKAKKPAGATPKKAKKAAGAKK 150



 Score = 32.3 bits (72), Expect = 0.65
 Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 5/80 (6%)

Query: 138 RGGGDKKPRRRGQKAAKSRGGGG-----KKPRGQKAAGAGAKKHRKPRRRGERAAAAGGK 192
           +  G KK  ++  K AK     G     K P+  KAA    K  + P +       A   
Sbjct: 144 KAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAAKP 203

Query: 193 KLQKAAAAKSRGGGGKKTAA 212
           K  K  AAK +    KK AA
Sbjct: 204 KAAKPKAAKPKAAKAKKAAA 223


>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
          Length = 1512

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 51/203 (25%), Positives = 87/203 (42%), Gaps = 34/203 (16%)

Query: 133 SRPQNRGGGDKKPRR---RGQKAAKSR----------GGGGKKPRGQKAAGAGAK---KH 176
           +R + R GG +K RR    GQ+A K R          GGGG       ++G G     ++
Sbjct: 93  ARGKRRAGGRQKRRRGPRAGQEAEKRRVFSLPQPQQDGGGG------ASSGGGVTPLVEY 146

Query: 177 RKPRRRGERAAAAGGKKLQKAA-AAKSRGGGGKKTAAAGGKKPR----RRRGQKAAKSRG 231
                + E+    GG     AA AA   GG G   A++ G + R     RR ++  +S  
Sbjct: 147 EDVSSQSEQGLLLGGASAATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSS 206

Query: 232 GGDKKLERQKAALTGVK-----SRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAG 286
           G  K+  R+     G +     S+   +    G+++ E  ++  S   GG +  K+A+A 
Sbjct: 207 GRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRR--KSASAT 264

Query: 287 AKSRGGRGEKPQKAEAGQGQNRR 309
           + S   R ++  KA   + ++ +
Sbjct: 265 SSSSSSRKDRDSKAHRSRTKSSK 287



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 46/196 (23%), Positives = 75/196 (38%), Gaps = 31/196 (15%)

Query: 127 GSRVCRSRPQNRGGGDKKPRRRGQKAA----KSRGGGGKKPRGQKAAGAGAKKHRKPRRR 182
           GS    S  Q RG G ++  RR ++++    K R    ++  GQ+     +K   +    
Sbjct: 179 GSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHS 238

Query: 183 GERAAAAGGKKLQKAAAAKSRGGGGKK-TAAAGGKKPRRRRGQKAAKSRGGGDK------ 235
           GE  A     ++ K+ ++ S GG  K  +A +     R+ R  KA +SR    K      
Sbjct: 239 GEERA-----EVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAY 293

Query: 236 --------------KLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQK 281
                         K  R++ +L+ +  R D  P+     Q  R + + S  GGG  P  
Sbjct: 294 KEPPKAYREDKTEPKAYRRRRSLSPLGGR-DDSPVSHRASQSLRSRKSPSPAGGGSSPYS 352

Query: 282 AAAAGAKSRGGRGEKP 297
                + S   R   P
Sbjct: 353 RRLPRSPSPYSRRRSP 368



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 61/294 (20%), Positives = 94/294 (31%), Gaps = 55/294 (18%)

Query: 64  PITPAPALLLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDA 123
           P  P P L L +    A   +  A  +   SPG      E +R     R A  R   +  
Sbjct: 52  PPPPPPLLFLAAPGTAAAAAAAAAASSSCFSPGPPL---EVKRLARGKRRAGGRQKRRRG 108

Query: 124 SRAGSRVCRSR------PQNRGGGDKKP---------------------------RRRGQ 150
            RAG    + R      PQ  GGG                                    
Sbjct: 109 PRAGQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAA 168

Query: 151 KAAKSRGGGGKKP---RGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGG 207
            AA   GG G  P    G +  G G++  R+PRR  +R +++G  K +     +  G  G
Sbjct: 169 TAAGGTGGSGGSPASSSGTQRRGEGSE--RRPRR--DRRSSSGRSKERHREHRRRDGQRG 224

Query: 208 KKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQ 267
              A+    +      ++A  ++ G       ++ + +   S    +  R  K  R R +
Sbjct: 225 GSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTK 284

Query: 268 NTKSRGGGGEKPQKA------------AAAGAKSRGGRGEKPQKAEAGQGQNRR 309
           ++K      ++P KA                    GGR + P    A Q    R
Sbjct: 285 SSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSR 338



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 37/153 (24%), Positives = 56/153 (36%), Gaps = 30/153 (19%)

Query: 164 RGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRG 223
           RG++ AG      R+ RRRG RA     K+   +     + GGG                
Sbjct: 94  RGKRRAGG-----RQKRRRGPRAGQEAEKRRVFSLPQPQQDGGG---------------- 132

Query: 224 QKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAA 283
              A S GG    +E +      V S+ ++  L GG             GG G  P  A+
Sbjct: 133 --GASSGGGVTPLVEYE-----DVSSQSEQGLLLGGASAATAATAAGGTGGSGGSP--AS 183

Query: 284 AAGAKSRGGRGEKPQKAEAGQGQNRRNEVGGQH 316
           ++G + RG   E+  + +      R  E   +H
Sbjct: 184 SSGTQRRGEGSERRPRRDRRSSSGRSKERHREH 216


>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
          Length = 1452

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 51/203 (25%), Positives = 87/203 (42%), Gaps = 34/203 (16%)

Query: 133 SRPQNRGGGDKKPRR---RGQKAAKSR----------GGGGKKPRGQKAAGAGAK---KH 176
           +R + R GG +K RR    GQ+A K R          GGGG       ++G G     ++
Sbjct: 93  ARGKRRAGGRQKRRRGPRAGQEAEKRRVFSLPQPQQDGGGG------ASSGGGVTPLVEY 146

Query: 177 RKPRRRGERAAAAGGKKLQKAA-AAKSRGGGGKKTAAAGGKKPR----RRRGQKAAKSRG 231
                + E+    GG     AA AA   GG G   A++ G + R     RR ++  +S  
Sbjct: 147 EDVSSQSEQGLLLGGASAATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSS 206

Query: 232 GGDKKLERQKAALTGVK-----SRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAG 286
           G  K+  R+     G +     S+   +    G+++ E  ++  S   GG +  K+A+A 
Sbjct: 207 GRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRR--KSASAT 264

Query: 287 AKSRGGRGEKPQKAEAGQGQNRR 309
           + S   R ++  KA   + ++ +
Sbjct: 265 SSSSSSRKDRDSKAHRSRTKSSK 287



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 46/196 (23%), Positives = 75/196 (38%), Gaps = 31/196 (15%)

Query: 127 GSRVCRSRPQNRGGGDKKPRRRGQKAA----KSRGGGGKKPRGQKAAGAGAKKHRKPRRR 182
           GS    S  Q RG G ++  RR ++++    K R    ++  GQ+     +K   +    
Sbjct: 179 GSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHS 238

Query: 183 GERAAAAGGKKLQKAAAAKSRGGGGKK-TAAAGGKKPRRRRGQKAAKSRGGGDK------ 235
           GE  A     ++ K+ ++ S GG  K  +A +     R+ R  KA +SR    K      
Sbjct: 239 GEERA-----EVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAY 293

Query: 236 --------------KLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQK 281
                         K  R++ +L+ +  R D  P+     Q  R + + S  GGG  P  
Sbjct: 294 KEPPKAYREDKTEPKAYRRRRSLSPLGGR-DDSPVSHRASQSLRSRKSPSPAGGGSSPYS 352

Query: 282 AAAAGAKSRGGRGEKP 297
                + S   R   P
Sbjct: 353 RRLPRSPSPYSRRRSP 368



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 61/294 (20%), Positives = 94/294 (31%), Gaps = 55/294 (18%)

Query: 64  PITPAPALLLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDA 123
           P  P P L L +    A   +  A  +   SPG      E +R     R A  R   +  
Sbjct: 52  PPPPPPLLFLAAPGTAAAAAAAAAASSSCFSPGPPL---EVKRLARGKRRAGGRQKRRRG 108

Query: 124 SRAGSRVCRSR------PQNRGGGDKKP---------------------------RRRGQ 150
            RAG    + R      PQ  GGG                                    
Sbjct: 109 PRAGQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAA 168

Query: 151 KAAKSRGGGGKKP---RGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGG 207
            AA   GG G  P    G +  G G++  R+PRR  +R +++G  K +     +  G  G
Sbjct: 169 TAAGGTGGSGGSPASSSGTQRRGEGSE--RRPRR--DRRSSSGRSKERHREHRRRDGQRG 224

Query: 208 KKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQ 267
              A+    +      ++A  ++ G       ++ + +   S    +  R  K  R R +
Sbjct: 225 GSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTK 284

Query: 268 NTKSRGGGGEKPQKA------------AAAGAKSRGGRGEKPQKAEAGQGQNRR 309
           ++K      ++P KA                    GGR + P    A Q    R
Sbjct: 285 SSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSR 338



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 37/153 (24%), Positives = 56/153 (36%), Gaps = 30/153 (19%)

Query: 164 RGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRG 223
           RG++ AG      R+ RRRG RA     K+   +     + GGG                
Sbjct: 94  RGKRRAGG-----RQKRRRGPRAGQEAEKRRVFSLPQPQQDGGG---------------- 132

Query: 224 QKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAA 283
              A S GG    +E +      V S+ ++  L GG             GG G  P  A+
Sbjct: 133 --GASSGGGVTPLVEYE-----DVSSQSEQGLLLGGASAATAATAAGGTGGSGGSP--AS 183

Query: 284 AAGAKSRGGRGEKPQKAEAGQGQNRRNEVGGQH 316
           ++G + RG   E+  + +      R  E   +H
Sbjct: 184 SSGTQRRGEGSERRPRRDRRSSSGRSKERHREH 216


>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
          Length = 417

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 62/256 (24%), Positives = 98/256 (38%), Gaps = 36/256 (14%)

Query: 81  QRRSMQATVAKAGS---PGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQN 137
           QRR    T  + GS   P   + G + R  E+    AP    ++   R   +     PQ 
Sbjct: 164 QRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQ-----PQC 218

Query: 138 RGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKA 197
           R  G    +RRG +++ S      + R ++AA A A     P  RG R      ++ Q+ 
Sbjct: 219 RPAGGTG-QRRGSRSSPSADQQRAQDREEEAAAAPA-----PTSRGHRTEKRKPQQPQRR 272

Query: 198 AAA---KSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAAL---------- 244
            A    + RG G   +A   G + R      A      G +  +R++  L          
Sbjct: 273 PAGGTGQRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQ 332

Query: 245 ---TGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEK-----PQKAAAAGAKSRGGRGEK 296
              +G  S  +++  +  +++        S G   EK     PQ+  AAG   R G G  
Sbjct: 333 RRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSS 392

Query: 297 PQKAEAGQGQNRRNEV 312
           P  A+  + Q+R  EV
Sbjct: 393 P-SADQQRAQDREEEV 407



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 61/234 (26%), Positives = 96/234 (41%), Gaps = 26/234 (11%)

Query: 94  SPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRGQKAA 153
           SP   + G + R  E+   +AP     +   R         P + G   +K R+R Q   
Sbjct: 56  SPSADQQGAQDREEEA--AAAPAADQQRAQDREEEAAAAPVPTSSGHRTEK-RKRLQLQC 112

Query: 154 KSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAA 213
           +  GG G++ RG +++ +  ++  + R   E  AAA      +    + R     +   A
Sbjct: 113 QPAGGTGQR-RGSRSSPSADQQRAQDR---EEEAAAAPVPTSRGHRTEKRKRQQPQRRPA 168

Query: 214 GGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLR----------GGKKQR 263
           GG   RR  G   +  + G   + E + AA     SRG +   R          GG  QR
Sbjct: 169 GGTGQRRGSGSSPSADQQGAQDR-EEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQR 227

Query: 264 ERGQNTKS--RGGGGEKPQKAAAAGA-KSRGGRGEK-----PQKAEAGQGQNRR 309
              +++ S  +    ++ ++AAAA A  SRG R EK     PQ+  AG    RR
Sbjct: 228 RGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR 281



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 6/169 (3%)

Query: 144 KPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSR 203
           KP R  Q+      GG  + RG  ++ +  ++  + R   E AAAA     Q+A   +  
Sbjct: 31  KPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDRE--EEAAAAPAADQQRAQDREEE 88

Query: 204 GGGGKKTAAAGGKKPRRRRGQKAAKSRGG-GDKKLERQKAALTGVKSRGDKKPLRGGKKQ 262
                   ++G +  +R+R Q   +  GG G ++  R   +    +++  ++        
Sbjct: 89  AAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVP 148

Query: 263 RERGQNTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNRRNE 311
             RG  T+ R    ++PQ+  A G   R G G  P   + G  Q+R  E
Sbjct: 149 TSRGHRTEKR--KRQQPQRRPAGGTGQRRGSGSSPSADQQG-AQDREEE 194



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 52/221 (23%), Positives = 89/221 (40%), Gaps = 18/221 (8%)

Query: 103 EPRRRESWTRSAP-RRCPYQDASRAGSRVCRSRPQNR-----GGGDKKPRRRGQKAAKSR 156
           +PR++E  TR    R     D      +    RPQ +      GG  +  RRG  ++ S 
Sbjct: 2   KPRQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQ--RRGSGSSPSA 59

Query: 157 GGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAA-----GGKKLQKAAAAKSR----GGGG 207
              G + R ++AA A A   ++ + R E AAAA      G + +K    + +    GG G
Sbjct: 60  DQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTG 119

Query: 208 KKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQ 267
           ++  +       ++R Q   +          R        + +  ++P  GG  QR    
Sbjct: 120 QRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPA-GGTGQRRGSG 178

Query: 268 NTKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNR 308
           ++ S    G + ++  AA A +   RG + +K +  Q Q R
Sbjct: 179 SSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCR 219



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 62/260 (23%), Positives = 94/260 (36%), Gaps = 47/260 (18%)

Query: 28  AQPVQAAEGDADELLELPALLQRPAG-----RG----PCATL-----RSHPITPAPALLL 73
           A PV  + G   E  +     +RPAG     RG    P A       R      APA   
Sbjct: 144 AAPVPTSRGHRTEKRKRQQPQRRPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAPTS 203

Query: 74  LSHSLPAQRRSMQATVAKAGSPGRGRLGK------EPRRRESWTRSAPRRCPYQDASRAG 127
             H    +R+  Q     AG  G+ R  +      + R ++    +A    P     R  
Sbjct: 204 RGHRTE-KRKPQQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTE 262

Query: 128 SRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKK---HRKPRR--- 181
            R  + +PQ R  G    +RRG   + S    G + R ++AA A A     HR  +R   
Sbjct: 263 KRKPQ-QPQRRPAGGTG-QRRGSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRL 320

Query: 182 -------------RGERAAAAGGK-----KLQKAAAAKSRGGGGKKTAAAGGKKPRRRRG 223
                        RG   +++  +     + ++AAAA      G +T     ++P+RR  
Sbjct: 321 QLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPA 380

Query: 224 QKAAKSRGGGDKKLERQKAA 243
               + RG G      Q+ A
Sbjct: 381 AGTGQRRGSGSSPSADQQRA 400


>gi|169172209 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 801

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 67/233 (28%), Positives = 91/233 (39%), Gaps = 36/233 (15%)

Query: 91  KAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQNRGGGDKKPRRRG- 149
           KAG+  R ++  + R R      AP   P       G  +  +R + RG    + R RG 
Sbjct: 10  KAGNEERDQVLADARPRRCCVVEAPGPMP------RGWILPGARSEERGARLAESRGRGV 63

Query: 150 -QKAAKSR--GGGGKKPRGQ-----KAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAK 201
             +A+ SR   GG     G      +  G G  +HR   R GE    AGG    +     
Sbjct: 64  TPRASWSRQPAGGPLSSEGHLLPLVQRDGGGLAEHRG--REGEEGVRAGGGGTGEVRGGG 121

Query: 202 SRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKK 261
           S G      AA  G+      G+ A   RG G   +ER+ A   G +  G +  LR   +
Sbjct: 122 SPGRQPVGRAAVTGEAGAGAAGRGAQSVRGPG---VERRVA--EGAQQFGPRVGLRQHAE 176

Query: 262 QRERGQN-TKSRGGGGEKPQKAAAAGAKSRGGRGEKPQKAEAGQGQNRRNEVG 313
           + ER Q   + RGGGG              GG G +  +   GQGQ R   VG
Sbjct: 177 RVERAQRAAEGRGGGG-------------GGGCGAQAHRRVVGQGQVRWEGVG 216



 Score = 36.2 bits (82), Expect = 0.045
 Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 11/112 (9%)

Query: 138 RGGGDKKPRRRGQKAAKSRGGGGKKPRG-QKAAGAGAKK------HRKPRRRGERAAAAG 190
           RGGG    +  G+ A     G G   RG Q   G G ++       +   R G R  A  
Sbjct: 118 RGGGSPGRQPVGRAAVTGEAGAGAAGRGAQSVRGPGVERRVAEGAQQFGPRVGLRQHAER 177

Query: 191 GKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKAAKSRGGGDKKLERQKA 242
            ++ Q+AA  +  GGGG      G +  RR  GQ   +  G G     R+ A
Sbjct: 178 VERAQRAAEGRGGGGGG----GCGAQAHRRVVGQGQVRWEGVGQAARGRRMA 225



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 11/100 (11%)

Query: 89  VAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQ--NRGGGDKKPR 146
           V   GSPGR  +G+     E+   +A R            RV     Q   R G  +   
Sbjct: 117 VRGGGSPGRQPVGRAAVTGEAGAGAAGRGAQSVRGPGVERRVAEGAQQFGPRVGLRQHAE 176

Query: 147 R--RGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGE 184
           R  R Q+AA+ RGGGG         G GA+ HR+   +G+
Sbjct: 177 RVERAQRAAEGRGGGG-------GGGCGAQAHRRVVGQGQ 209



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 39/158 (24%), Positives = 59/158 (37%), Gaps = 31/158 (19%)

Query: 160 GKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPR 219
           G  PRG    GA +++      RG R A + G+ +   A+   +  GG   ++ G   P 
Sbjct: 35  GPMPRGWILPGARSEE------RGARLAESRGRGVTPRASWSRQPAGGP-LSSEGHLLP- 86

Query: 220 RRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGG--GE 277
                     R GG     R +    GV++ G              G   + RGGG  G 
Sbjct: 87  -------LVQRDGGGLAEHRGREGEEGVRAGG--------------GGTGEVRGGGSPGR 125

Query: 278 KPQKAAAAGAKSRGGRGEKPQKAEAGQGQNRRNEVGGQ 315
           +P   AA   ++  G   +  ++  G G  RR   G Q
Sbjct: 126 QPVGRAAVTGEAGAGAAGRGAQSVRGPGVERRVAEGAQ 163


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,671,796
Number of Sequences: 37866
Number of extensions: 905755
Number of successful extensions: 10079
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 211
Number of HSP's successfully gapped in prelim test: 857
Number of HSP's that attempted gapping in prelim test: 5848
Number of HSP's gapped (non-prelim): 3010
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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