BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239753110 PREDICTED: doublecortin domain-containing protein ENSP00000382097-like [Homo sapiens] (530 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239753110 PREDICTED: doublecortin domain-containing protein E... 1102 0.0 gi|239747673 PREDICTED: doublecortin domain-containing protein E... 794 0.0 gi|239741542 PREDICTED: doublecortin domain-containing protein E... 670 0.0 gi|117938307 doublecortin domain containing 2 [Homo sapiens] 186 6e-47 gi|150456471 doublecortin domain containing 2B [Homo sapiens] 154 2e-37 gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] 74 3e-13 gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] 74 3e-13 gi|4758128 doublecortin-like kinase 1 [Homo sapiens] 72 1e-12 gi|30181244 doublecortin isoform c [Homo sapiens] 71 2e-12 gi|30181242 doublecortin isoform b [Homo sapiens] 71 2e-12 gi|30181240 doublecortin isoform c [Homo sapiens] 71 2e-12 gi|30181246 doublecortin isoform a [Homo sapiens] 71 2e-12 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 65 2e-10 gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens] 62 2e-09 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 39 0.009 gi|93102424 hypothetical protein LOC23116 [Homo sapiens] 33 0.65 gi|21264332 sialyltransferase 7A [Homo sapiens] 33 0.84 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 33 0.84 gi|20149646 hypothetical protein LOC54964 [Homo sapiens] 32 1.1 gi|239755534 PREDICTED: doublecortin domain containing 5 [Homo s... 32 1.4 gi|239750000 PREDICTED: doublecortin domain containing 5 [Homo s... 32 1.4 gi|239744311 PREDICTED: doublecortin domain containing 5 [Homo s... 32 1.4 gi|193083122 translocase of outer mitochondrial membrane 40 [Hom... 32 1.4 gi|193083120 translocase of outer mitochondrial membrane 40 [Hom... 32 1.4 gi|5174723 translocase of outer mitochondrial membrane 40 [Homo ... 32 1.4 gi|219802034 nuclear factor related to kappaB binding protein is... 32 1.9 gi|23346420 nuclear factor related to kappaB binding protein iso... 32 1.9 gi|7706657 cell division cycle 40 homolog [Homo sapiens] 31 2.5 gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens] 31 3.2 gi|153792060 SERTA domain containing 1 [Homo sapiens] 31 3.2 >gi|239753110 PREDICTED: doublecortin domain-containing protein ENSP00000382097-like [Homo sapiens] Length = 530 Score = 1102 bits (2851), Expect = 0.0 Identities = 530/530 (100%), Positives = 530/530 (100%) Query: 1 MLAASSSSFPELCRHAPHLPGLPVAPSPVSALGWSGPPVGGARAWARLCRRRCPRCRSLS 60 MLAASSSSFPELCRHAPHLPGLPVAPSPVSALGWSGPPVGGARAWARLCRRRCPRCRSLS Sbjct: 1 MLAASSSSFPELCRHAPHLPGLPVAPSPVSALGWSGPPVGGARAWARLCRRRCPRCRSLS 60 Query: 61 APASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQL 120 APASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQL Sbjct: 61 APASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQL 120 Query: 121 TEQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRK 180 TEQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRK Sbjct: 121 TEQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRK 180 Query: 181 LKEIKPVVHCDINVPSKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATI 240 LKEIKPVVHCDINVPSKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATI Sbjct: 181 LKEIKPVVHCDINVPSKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATI 240 Query: 241 GEKVFPLGGVRKLFTMNGHLLGDSKDLQDNHFYVAVGLETFKYFPYWKSPRVPSEVQHVS 300 GEKVFPLGGVRKLFTMNGHLLGDSKDLQDNHFYVAVGLETFKYFPYWKSPRVPSEVQHVS Sbjct: 241 GEKVFPLGGVRKLFTMNGHLLGDSKDLQDNHFYVAVGLETFKYFPYWKSPRVPSEVQHVS 300 Query: 301 GVKSYLFHSLTEHSPRRQAPSPFYRTSERPETTQLTWRARDPVLVDSKGKEPCKYDGIPP 360 GVKSYLFHSLTEHSPRRQAPSPFYRTSERPETTQLTWRARDPVLVDSKGKEPCKYDGIPP Sbjct: 301 GVKSYLFHSLTEHSPRRQAPSPFYRTSERPETTQLTWRARDPVLVDSKGKEPCKYDGIPP 360 Query: 361 KTQDSVYYAKEEKKKTLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQ 420 KTQDSVYYAKEEKKKTLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQ Sbjct: 361 KTQDSVYYAKEEKKKTLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQ 420 Query: 421 SWTGWVAASEWAKPGELARAWLAAWPHSAPGPCCLLGRLLALRQGDWHTHGHREGAYIRV 480 SWTGWVAASEWAKPGELARAWLAAWPHSAPGPCCLLGRLLALRQGDWHTHGHREGAYIRV Sbjct: 421 SWTGWVAASEWAKPGELARAWLAAWPHSAPGPCCLLGRLLALRQGDWHTHGHREGAYIRV 480 Query: 481 VRTFQAISEGRTEGLACGNCNGSKRDRISGWKLWGVAGCQREGDSLVVVA 530 VRTFQAISEGRTEGLACGNCNGSKRDRISGWKLWGVAGCQREGDSLVVVA Sbjct: 481 VRTFQAISEGRTEGLACGNCNGSKRDRISGWKLWGVAGCQREGDSLVVVA 530 >gi|239747673 PREDICTED: doublecortin domain-containing protein ENSP00000382097-like [Homo sapiens] Length = 714 Score = 794 bits (2050), Expect = 0.0 Identities = 393/461 (85%), Positives = 396/461 (85%), Gaps = 53/461 (11%) Query: 16 APHLPGLPVAPSPVSALGWSGPPVGGARAWARLCRRRCPRCRSLSAPASEERGAAMGTRG 75 +P P PSP A GWSGPPVGGARAWARLCRRRCPRCRSLSAPASEERGAAMGTRG Sbjct: 122 SPSSPRPVPVPSPSCASGWSGPPVGGARAWARLCRRRCPRCRSLSAPASEERGAAMGTRG 181 Query: 76 PSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFT 135 PSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFT Sbjct: 182 PSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFT 241 Query: 136 PTRGHRVLGLDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVHCDINVP 195 PTRGHRVLGLDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVHCDINVP Sbjct: 242 PTRGHRVLGLDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVHCDINVP 301 Query: 196 SKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKVFPLGGVRKLFT 255 SKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKVFPLGGVRKLFT Sbjct: 302 SKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKVFPLGGVRKLFT 361 Query: 256 MNGHLLGDSKDLQDNHFYVAVGLETFKYFPYWKSPRVPSEVQHVSGVKSYLFHSLTEHSP 315 MNGHLLGDSKDLQDNHFYVAVGLETFKYFPYWKSPRV S+ Sbjct: 362 MNGHLLGDSKDLQDNHFYVAVGLETFKYFPYWKSPRVDSK-------------------- 401 Query: 316 RRQAPSPFYRTSERPETTQLTWRARDPVLVDSKGKEPCKYDGIPPKTQDSVYYAKEEKKK 375 GKEPCKYDGIPPKTQDSVYYAKEEKKK Sbjct: 402 ---------------------------------GKEPCKYDGIPPKTQDSVYYAKEEKKK 428 Query: 376 TLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQSWTGWVAASEWAKPG 435 TLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQSWTGWVAASEWAKPG Sbjct: 429 TLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQSWTGWVAASEWAKPG 488 Query: 436 ELARAWLAAWPHSAPGPCCLLGRLLALRQGDWHTHGHREGA 476 ELARAWLAAWPHSAPGPCCLLGRLLALRQGDWHTHGHRE + Sbjct: 489 ELARAWLAAWPHSAPGPCCLLGRLLALRQGDWHTHGHREAS 529 >gi|239741542 PREDICTED: doublecortin domain-containing protein ENSP00000382097-like [Homo sapiens] Length = 510 Score = 670 bits (1729), Expect = 0.0 Identities = 339/406 (83%), Positives = 342/406 (84%), Gaps = 53/406 (13%) Query: 16 APHLPGLPVAPSPVSALGWSGPPVGGARAWARLCRRRCPRCRSLSAPASEERGAAMGTRG 75 +P P PSP A GWSGPPVGGARAWARLCRRRCPRCRSLSAPASEERGAAMGTRG Sbjct: 122 SPSSPRPVPVPSPSCASGWSGPPVGGARAWARLCRRRCPRCRSLSAPASEERGAAMGTRG 181 Query: 76 PSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFT 135 PSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFT Sbjct: 182 PSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFT 241 Query: 136 PTRGHRVLGLDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVHCDINVP 195 PTRGHRVLGLDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVHCDINVP Sbjct: 242 PTRGHRVLGLDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVHCDINVP 301 Query: 196 SKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKVFPLGGVRKLFT 255 SKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKVFPLGGVRKLFT Sbjct: 302 SKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKVFPLGGVRKLFT 361 Query: 256 MNGHLLGDSKDLQDNHFYVAVGLETFKYFPYWKSPRVPSEVQHVSGVKSYLFHSLTEHSP 315 MNGHLLGDSKDLQDNHFYVAVGLETFKYFPYWKSPRV S+ Sbjct: 362 MNGHLLGDSKDLQDNHFYVAVGLETFKYFPYWKSPRVDSK-------------------- 401 Query: 316 RRQAPSPFYRTSERPETTQLTWRARDPVLVDSKGKEPCKYDGIPPKTQDSVYYAKEEKKK 375 GKEPCKYDGIPPKTQDSVYYAKEEKKK Sbjct: 402 ---------------------------------GKEPCKYDGIPPKTQDSVYYAKEEKKK 428 Query: 376 TLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQS 421 TLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQ+ Sbjct: 429 TLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQA 474 >gi|117938307 doublecortin domain containing 2 [Homo sapiens] Length = 476 Score = 186 bits (471), Expect = 6e-47 Identities = 116/357 (32%), Positives = 192/357 (53%), Gaps = 26/357 (7%) Query: 72 GTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFG-V 130 G+ S+ + K+++VYRNGDPFY G++ V+ ++ ++FE L+++T V PFG V Sbjct: 3 GSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFGAV 62 Query: 131 RRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDYIHI--VPRKPAKIRKLKEIKPVV 188 R ++TP GHR+ LD +Q+GG YVA G+E FK+L+Y+ I + ++P ++ E+KPV+ Sbjct: 63 RNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVN-TEVKPVI 121 Query: 189 HCDINVPSKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKV-FPL 247 H INV ++++ + I + NG L P ++++IP+ +L+ WD VL + EK+ Sbjct: 122 HSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLRS 181 Query: 248 GGVRKLFTMNGHLLGDSKDLQDNHFYVAVGLETFKYFPYWKSPRVPSEVQHVSGVKSYLF 307 G V +L+T+ G L+ +L++ FYVAVG + FK PY LF Sbjct: 182 GAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPY----------------SELLF 225 Query: 308 HSLTEHSPRRQAPS--PFYRTSERPETTQLTWRARDPV-LVDSKGKEPCKYDGIPPK-TQ 363 T P Q S P S + + + ++ V D+ +P K G Sbjct: 226 DKSTMRRPFGQKASSLPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNS 285 Query: 364 DSVYYAKEEKKKTLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQ 420 + + K+ K ++ + EG ++KA ET+GA +V+E+ + Q+EVPVDQ Sbjct: 286 EKLTKLKQNVKLKNSQETIPNSDEG-IFKAGAERSETRGAAEVQEDEDTQVEVPVDQ 341 >gi|150456471 doublecortin domain containing 2B [Homo sapiens] Length = 349 Score = 154 bits (389), Expect = 2e-37 Identities = 126/350 (36%), Positives = 166/350 (47%), Gaps = 53/350 (15%) Query: 85 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLG 144 AK +VVYRNGDPF+ G + V+++RR T EA L ++T V P VR L+TP GH V Sbjct: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTN 67 Query: 145 LDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVH--CDINVPSKWQTYH 202 L L+ G+YVAAG ERF +L Y+ + P + PV CD + Q Sbjct: 68 LADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIGR--QLPA 125 Query: 203 RISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLL 261 +I+VF NG L PP + + + + DW+ VL + EKV G V KL T+ G L Sbjct: 126 GAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTLEGLPL 185 Query: 262 GDSKDLQDNHFYVAVGLETFKYFPYWK----SPRVPSEVQHVSGVKSYLFHSLTEHSPRR 317 K+L H+YVAVG + FK PY + SP +P G KS P R Sbjct: 186 SAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPPGSKS---------RPHR 236 Query: 318 QAPSPFYRTSERPETTQLTWRARDPVLVDSKGKEPCKYDGIPPKTQDSVYYAKEE----- 372 Q R + TQ KEP D I P S +YA+ + Sbjct: 237 QGAQ-----GHRAQVTQ------------PSPKEP---DRIKP----SAFYARPQQTIQP 272 Query: 373 --KKKTLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQ 420 K TL+ P G G VY AP KET GAL+V ++ + Q E P+DQ Sbjct: 273 RSKLPTLSFP---SGVIG-VYGAPHRRKETAGALEVADDEDTQTEEPLDQ 318 >gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] Length = 765 Score = 74.3 bits (181), Expect = 3e-13 Identities = 64/232 (27%), Positives = 105/232 (45%), Gaps = 7/232 (3%) Query: 59 LSAPASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLE 118 + +PA + TR A AK YRNGD ++ G F +S R +F+ALL Sbjct: 45 IPSPAHSAHCSFYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLI 104 Query: 119 QLT----EQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDYI-HIVPR 173 +LT + V++P GVR ++T +V LD L G YV A E F+++DY +I P Sbjct: 105 ELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPN 164 Query: 174 KPAKIRKLKEIKPVVHCDINVPSKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDW 233 I+ + K + + V +G +I++ K + + Sbjct: 165 WSVNIKGGTSRALAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSF 224 Query: 234 DIVLATIGEKV-FPLGGVRKLFTMNGHLLGDSKD-LQDNHFYVAVGLETFKY 283 + VL I E + G V++L T++G + +D D+ ++A G E F+Y Sbjct: 225 EQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRY 276 >gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] Length = 766 Score = 74.3 bits (181), Expect = 3e-13 Identities = 64/232 (27%), Positives = 105/232 (45%), Gaps = 7/232 (3%) Query: 59 LSAPASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLE 118 + +PA + TR A AK YRNGD ++ G F +S R +F+ALL Sbjct: 45 IPSPAHSAHCSFYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLI 104 Query: 119 QLT----EQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDYI-HIVPR 173 +LT + V++P GVR ++T +V LD L G YV A E F+++DY +I P Sbjct: 105 ELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPN 164 Query: 174 KPAKIRKLKEIKPVVHCDINVPSKWQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDW 233 I+ + K + + V +G +I++ K + + Sbjct: 165 WSVNIKGGTSRALAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSF 224 Query: 234 DIVLATIGEKV-FPLGGVRKLFTMNGHLLGDSKD-LQDNHFYVAVGLETFKY 283 + VL I E + G V++L T++G + +D D+ ++A G E F+Y Sbjct: 225 EQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRY 276 >gi|4758128 doublecortin-like kinase 1 [Homo sapiens] Length = 729 Score = 72.4 bits (176), Expect = 1e-12 Identities = 76/314 (24%), Positives = 132/314 (42%), Gaps = 18/314 (5%) Query: 52 RCPRCRSLSAPASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAA 111 R R L +P + TR AK + YRNGD ++ G + +S R Sbjct: 23 RGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFR 82 Query: 112 TFEALLEQLT----EQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDY 167 +FEALL LT + V++P GVR ++T ++ LD L G YV E FK+L+Y Sbjct: 83 SFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEY 142 Query: 168 I-HIVPRKPAKIRKLKEIKPV--VHCDINVPSKWQTYHRISRH--INVFTNGRLFIPPAK 222 ++ P ++ + V + PS+ + R + + +G + Sbjct: 143 TKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVR 202 Query: 223 IIIPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLLGDSKD-LQDNHFYVAVGLET 280 I++ K + ++ VL I + + G V++L+T++G + +D D+ ++A G E Sbjct: 203 ILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEK 262 Query: 281 FKYFPYWKSPRVPSEVQHVSGVKSYLFHSLTEHSPR--RQAPSPFYRTSERPETTQLTWR 338 F+Y + V VKS + + S R ++P P R+ T+ + Sbjct: 263 FRYQDDFLLDESECRV-----VKSTSYTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGT 317 Query: 339 ARDPVLVDSKGKEP 352 + GK P Sbjct: 318 PGSQLSTPRSGKSP 331 >gi|30181244 doublecortin isoform c [Homo sapiens] Length = 360 Score = 71.2 bits (173), Expect = 2e-12 Identities = 59/241 (24%), Positives = 111/241 (46%), Gaps = 9/241 (3%) Query: 52 RCPRCRSLSAPASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAA 111 R R L +P + TR A + AK + YRNGD ++ G + +S R Sbjct: 19 RGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFR 78 Query: 112 TFEALLEQLT----EQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDY 167 +F+ALL LT + +++P GVR ++T ++ +D L+ G YV + FK+++Y Sbjct: 79 SFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEY 138 Query: 168 I-HIVPRKPAKIRKLKEIK-PVVHCDINVPSKWQTYHRI-SRHINVFTNGRLFIPPAKII 224 ++ P ++ +K P N + + + + + +G +++ Sbjct: 139 TKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVL 198 Query: 225 IPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLLGDSKD-LQDNHFYVAVGLETFK 282 + K + ++ VL I E + G V+KL+T++G + D D+ ++A G E F+ Sbjct: 199 LNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 258 Query: 283 Y 283 Y Sbjct: 259 Y 259 >gi|30181242 doublecortin isoform b [Homo sapiens] Length = 365 Score = 71.2 bits (173), Expect = 2e-12 Identities = 59/241 (24%), Positives = 111/241 (46%), Gaps = 9/241 (3%) Query: 52 RCPRCRSLSAPASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAA 111 R R L +P + TR A + AK + YRNGD ++ G + +S R Sbjct: 19 RGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFR 78 Query: 112 TFEALLEQLT----EQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDY 167 +F+ALL LT + +++P GVR ++T ++ +D L+ G YV + FK+++Y Sbjct: 79 SFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEY 138 Query: 168 I-HIVPRKPAKIRKLKEIK-PVVHCDINVPSKWQTYHRI-SRHINVFTNGRLFIPPAKII 224 ++ P ++ +K P N + + + + + +G +++ Sbjct: 139 TKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVL 198 Query: 225 IPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLLGDSKD-LQDNHFYVAVGLETFK 282 + K + ++ VL I E + G V+KL+T++G + D D+ ++A G E F+ Sbjct: 199 LNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 258 Query: 283 Y 283 Y Sbjct: 259 Y 259 >gi|30181240 doublecortin isoform c [Homo sapiens] Length = 360 Score = 71.2 bits (173), Expect = 2e-12 Identities = 59/241 (24%), Positives = 111/241 (46%), Gaps = 9/241 (3%) Query: 52 RCPRCRSLSAPASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAA 111 R R L +P + TR A + AK + YRNGD ++ G + +S R Sbjct: 19 RGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFR 78 Query: 112 TFEALLEQLT----EQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDY 167 +F+ALL LT + +++P GVR ++T ++ +D L+ G YV + FK+++Y Sbjct: 79 SFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEY 138 Query: 168 I-HIVPRKPAKIRKLKEIK-PVVHCDINVPSKWQTYHRI-SRHINVFTNGRLFIPPAKII 224 ++ P ++ +K P N + + + + + +G +++ Sbjct: 139 TKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVL 198 Query: 225 IPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLLGDSKD-LQDNHFYVAVGLETFK 282 + K + ++ VL I E + G V+KL+T++G + D D+ ++A G E F+ Sbjct: 199 LNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 258 Query: 283 Y 283 Y Sbjct: 259 Y 259 >gi|30181246 doublecortin isoform a [Homo sapiens] Length = 441 Score = 71.2 bits (173), Expect = 2e-12 Identities = 59/241 (24%), Positives = 111/241 (46%), Gaps = 9/241 (3%) Query: 52 RCPRCRSLSAPASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAA 111 R R L +P + TR A + AK + YRNGD ++ G + +S R Sbjct: 100 RGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFR 159 Query: 112 TFEALLEQLT----EQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRERFKELDY 167 +F+ALL LT + +++P GVR ++T ++ +D L+ G YV + FK+++Y Sbjct: 160 SFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEY 219 Query: 168 I-HIVPRKPAKIRKLKEIK-PVVHCDINVPSKWQTYHRI-SRHINVFTNGRLFIPPAKII 224 ++ P ++ +K P N + + + + + +G +++ Sbjct: 220 TKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVL 279 Query: 225 IPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLLGDSKD-LQDNHFYVAVGLETFK 282 + K + ++ VL I E + G V+KL+T++G + D D+ ++A G E F+ Sbjct: 280 LNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR 339 Query: 283 Y 283 Y Sbjct: 340 Y 340 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 64.7 bits (156), Expect = 2e-10 Identities = 35/104 (33%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Query: 57 RSLSAPASEERGAAMGTRGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEAL 116 R+ AP+ E R PS TPAK I + GDP + G + + +R TF AL Sbjct: 6 RNAQAPSHRECFLPSVARTPSV-TKVTPAKKITFLKRGDPRFAGVRLAVHQRAFKTFSAL 64 Query: 117 LEQLTEQVDVPFGVRRLFTPTRGHRVLGLDALQAGGKYVAAGRE 160 +++L+++V + FGVR + TP H + L+ L+ GG Y+ + ++ Sbjct: 65 MDELSQRVPLSFGVRSVTTPRGLHSLSALEQLEDGGCYLCSDKK 108 >gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens] Length = 2156 Score = 61.6 bits (148), Expect = 2e-09 Identities = 41/132 (31%), Positives = 65/132 (49%), Gaps = 6/132 (4%) Query: 85 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLG 144 AK I Y++GDP + G + V++ R +F+ALL+ L+ +V +PFGVR + TP H + Sbjct: 35 AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPRGRHSITR 94 Query: 145 LDALQAGGKYVAAGRERFK--ELDYIHIVPRKPAKIRKLKEIKPVVHCDINVPSKWQTYH 202 L+ L+ G Y+ + + + +LD PR R + P + P Sbjct: 95 LEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVAVAAPG----MP 150 Query: 203 RISRHINVFTNG 214 R R + VF NG Sbjct: 151 RPPRSLVVFRNG 162 Score = 56.6 bits (135), Expect = 5e-08 Identities = 40/92 (43%), Positives = 55/92 (59%), Gaps = 5/92 (5%) Query: 77 SAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTP 136 +AP P +++VV+RNGDP + +LSRR +FEA L+ LTE + P V +L+ Sbjct: 145 AAPGMPRPPRSLVVFRNGDP-KTRRAVLLSRRVTQSFEAFLQHLTEVMQRP--VVKLYA- 200 Query: 137 TRGHRVLGLDA-LQAGGKYVAAGRERFKELDY 167 T G RV L A + + G VAAGRE FK +Y Sbjct: 201 TDGRRVPSLQAVILSSGAVVAAGREPFKPGNY 232 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 39.3 bits (90), Expect = 0.009 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Query: 346 DSKGKEPCKYDGIPPKTQDSVYYAKEEKKKTLAEPLVQRGAEGDVYKAPTPSKETQGALD 405 DSK +E K + PK ++ A E+ K++ E ++ D K PTP KE ++ Sbjct: 858 DSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE--AKKEEAEDKKKVPTPEKEAPAKVE 915 Query: 406 VKEEHNVQLEVPVDQSWTGWVAASEWAKPGELARA 440 VKE+ + + V + A E +KP E A Sbjct: 916 VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEA 950 >gi|93102424 hypothetical protein LOC23116 [Homo sapiens] Length = 1720 Score = 33.1 bits (74), Expect = 0.65 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%) Query: 81 DTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPF---GVRRLFTPT 137 + TPA+ +V NG Y G+K + FE +LE+ D+P+ VR L Sbjct: 1369 NVTPARAVVSLINGGQRYYGRKMLFFMMCHPNFEKMLEKYVPSKDLPYIKDSVRNL--QQ 1426 Query: 138 RGHRVLGLDALQAGGK 153 +G + LD A G+ Sbjct: 1427 KGLGEIPLDTPSAKGR 1442 >gi|21264332 sialyltransferase 7A [Homo sapiens] Length = 600 Score = 32.7 bits (73), Expect = 0.84 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 18/124 (14%) Query: 288 KSPRV-PSEVQHVSGVKSYLFHSLTEHSPRRQAPSPFYRTS----ERPETTQLTWRARDP 342 K P+ PS Q +K SL + P+ QAP+ RT+ PE L + + Sbjct: 36 KEPQTKPSRHQRTENIKERSLQSLAK--PKSQAPTRARRTTIYAEPVPENNALNTQTQPK 93 Query: 343 V-LVDSKGKEPCKYDGIPPKTQDSVYYAKE-------EKKKTLAEPLVQRGAEGDVYKAP 394 +GKE + PP+ QD V + + EK+KT+ L RG + + Sbjct: 94 AHTTGDRGKEA---NQAPPEEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASGR 150 Query: 395 TPSK 398 T ++ Sbjct: 151 TEAQ 154 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 32.7 bits (73), Expect = 0.84 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 24/148 (16%) Query: 315 PRRQA-PSPF-YRTSERPETTQLTWRARDP-VLVDSKGKEPCKYDGIPPKTQDSVYYAKE 371 PRR + PSP S+ P T Q +A + L + +E KY + +V+ KE Sbjct: 109 PRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLA----AKKAVWLEKE 164 Query: 372 EKKKTLAEPLVQ--------RGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQSWT 423 EK K L E +Q + + + +A ++ Q KE + ++ V ++W Sbjct: 165 EKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWA 224 Query: 424 GWVAASEWAKPGELARAWLAAWPHSAPG 451 + W+ W A HS+PG Sbjct: 225 E-IRQQRWS--------WAGALHHSSPG 243 >gi|20149646 hypothetical protein LOC54964 [Homo sapiens] Length = 341 Score = 32.3 bits (72), Expect = 1.1 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 429 SEWAKPGELARAWLAAWPHSAPGPCCLLGRLLALRQGDWHTH 470 S+W+ PG W + P + P P L RL+ + G WH H Sbjct: 173 SQWSTPGSTPSRWPSPSPTAMPSPEDL--RLVLMPWGPWHCH 212 >gi|239755534 PREDICTED: doublecortin domain containing 5 [Homo sapiens] Length = 1020 Score = 32.0 bits (71), Expect = 1.4 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 5/51 (9%) Query: 85 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFT 135 A I+ Y+NGD + GK V A TF LL + TEQ+ + +++T Sbjct: 645 AVKIIAYKNGDGYRNGKLIV-----AGTFPMLLTECTEQLGLARAASKVYT 690 >gi|239750000 PREDICTED: doublecortin domain containing 5 [Homo sapiens] Length = 1020 Score = 32.0 bits (71), Expect = 1.4 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 5/51 (9%) Query: 85 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFT 135 A I+ Y+NGD + GK V A TF LL + TEQ+ + +++T Sbjct: 645 AVKIIAYKNGDGYRNGKLIV-----AGTFPMLLTECTEQLGLARAASKVYT 690 >gi|239744311 PREDICTED: doublecortin domain containing 5 [Homo sapiens] Length = 1020 Score = 32.0 bits (71), Expect = 1.4 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 5/51 (9%) Query: 85 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFT 135 A I+ Y+NGD + GK V A TF LL + TEQ+ + +++T Sbjct: 645 AVKIIAYKNGDGYRNGKLIV-----AGTFPMLLTECTEQLGLARAASKVYT 690 >gi|193083122 translocase of outer mitochondrial membrane 40 [Homo sapiens] Length = 361 Score = 32.0 bits (71), Expect = 1.4 Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Query: 1 MLAASSSSFPELCRHAPHLPGLPVAPSPVSALGWSGPPVGGARAWARLCRR---RCPRCR 57 +LAASS AP L GLP P P S G++ PP+GG+ R R P Sbjct: 4 VLAASSPPAGPPPPPAPALVGLP--PPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAA 61 Query: 58 SLSAPASEERGA 69 + SA + E GA Sbjct: 62 TASASGAAEDGA 73 >gi|193083120 translocase of outer mitochondrial membrane 40 [Homo sapiens] Length = 361 Score = 32.0 bits (71), Expect = 1.4 Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Query: 1 MLAASSSSFPELCRHAPHLPGLPVAPSPVSALGWSGPPVGGARAWARLCRR---RCPRCR 57 +LAASS AP L GLP P P S G++ PP+GG+ R R P Sbjct: 4 VLAASSPPAGPPPPPAPALVGLP--PPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAA 61 Query: 58 SLSAPASEERGA 69 + SA + E GA Sbjct: 62 TASASGAAEDGA 73 >gi|5174723 translocase of outer mitochondrial membrane 40 [Homo sapiens] Length = 361 Score = 32.0 bits (71), Expect = 1.4 Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Query: 1 MLAASSSSFPELCRHAPHLPGLPVAPSPVSALGWSGPPVGGARAWARLCRR---RCPRCR 57 +LAASS AP L GLP P P S G++ PP+GG+ R R P Sbjct: 4 VLAASSPPAGPPPPPAPALVGLP--PPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAA 61 Query: 58 SLSAPASEERGA 69 + SA + E GA Sbjct: 62 TASASGAAEDGA 73 >gi|219802034 nuclear factor related to kappaB binding protein isoform 1 [Homo sapiens] Length = 1299 Score = 31.6 bits (70), Expect = 1.9 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 5/55 (9%) Query: 17 PHLPGLPVAPSPVSALGWSGP-----PVGGARAWARLCRRRCPRCRSLSAPASEE 66 P LP +P++P PVSA+ SGP P + + P ++ +PAS + Sbjct: 728 PALPAIPISPPPVSAVNKSGPSTVSEPAKSSSGVLLVSSPTMPHLGTMLSPASSQ 782 >gi|23346420 nuclear factor related to kappaB binding protein isoform 2 [Homo sapiens] Length = 1324 Score = 31.6 bits (70), Expect = 1.9 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 5/55 (9%) Query: 17 PHLPGLPVAPSPVSALGWSGP-----PVGGARAWARLCRRRCPRCRSLSAPASEE 66 P LP +P++P PVSA+ SGP P + + P ++ +PAS + Sbjct: 753 PALPAIPISPPPVSAVNKSGPSTVSEPAKSSSGVLLVSSPTMPHLGTMLSPASSQ 807 >gi|7706657 cell division cycle 40 homolog [Homo sapiens] Length = 579 Score = 31.2 bits (69), Expect = 2.5 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 12/104 (11%) Query: 160 ERFKELDYIHIVPRKPAKIRKLK--EIKPVVHCDINVPSKWQTYHRISRHINVFTNGRLF 217 E KELD I +K K + K E K ++H + ++Y I + + V N R Sbjct: 211 EEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGV--NLRST 268 Query: 218 IPPAKIIIPKFSLSDWDIVLATIGEKVFPLGGVRKLFTMNGHLL 261 +PP K +PK + W + +LF ++GHLL Sbjct: 269 MPPEKCYLPKKQIHVWSGHTKGV--------SAVRLFPLSGHLL 304 >gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens] Length = 589 Score = 30.8 bits (68), Expect = 3.2 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 9/95 (9%) Query: 416 VPVDQSWTGWVAASEWAKPGELARAWLAAWPHSAPGPCCLLGRLLALRQGDWHTHGH--- 472 VP+ S GW A+ + + WL +P S P L + G WH GH Sbjct: 231 VPLGASLQGWGTAAGPSPELGSGQGWLPFYPFSTADPS---AEDLHMASGPWHHPGHIFC 287 Query: 473 REGAYIRVVRTFQAISEGRTEGLACGNCNGSKRDR 507 +E A+ +GR GL G +R R Sbjct: 288 QEEAW---TENLNFTPDGRANGLPRALNQGLQRTR 319 >gi|153792060 SERTA domain containing 1 [Homo sapiens] Length = 236 Score = 30.8 bits (68), Expect = 3.2 Identities = 16/40 (40%), Positives = 21/40 (52%) Query: 3 AASSSSFPELCRHAPHLPGLPVAPSPVSALGWSGPPVGGA 42 AA S+S L H+ GL AP P++ G G +GGA Sbjct: 109 AALSASMASLLEDLSHIEGLSQAPQPLADEGPPGRSIGGA 148 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.436 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,082,999 Number of Sequences: 37866 Number of extensions: 1242252 Number of successful extensions: 4003 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 3924 Number of HSP's gapped (non-prelim): 67 length of query: 530 length of database: 18,247,518 effective HSP length: 107 effective length of query: 423 effective length of database: 14,195,856 effective search space: 6004847088 effective search space used: 6004847088 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.